{"meta":{"query_hash":"319749754dc4","filters":{"topic":"Receptor Mechanisms and Signaling"},"cohort_total":2202,"direct_labels_cover":2,"predictions_cover":2202,"exported":2202,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/319749754dc4","api":"https://metacan.xera.ac/api/v1/cohort?topic=Receptor+Mechanisms+and+Signaling"},"results":[{"id":"W1002946855","doi":"10.1096/fasebj.29.1_supplement.935.2","title":"Transmembrane Domains IV and V Form an Interface in Human Angiotensin II Type 1 Receptor Homomers","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"G protein-coupled receptor; Homology modeling; Angiotensin II; Transmembrane domain; Computational biology; Receptor; Transmembrane protein; Docking (animal); Chemistry; Biophysics; Biology; Biochemistry; Medicine","score_opus":0.021056925498036963,"score_gpt":0.26610668429546214,"score_spread":0.2450497587974252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1002946855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759036,0.0008089357,0.0008326702,0.00027253196,0.00022514687,0.00007672515,0.0000035902085,0.0000047433477,0.00018530061],"genre_scores_gemma":[0.9984379,0.00016021136,0.00065673323,0.00012215518,0.00026884777,0.0000010254865,0.000013948833,0.000017137769,0.0003220393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999278,0.000086514694,0.0001742406,0.00014227472,0.0001142617,0.0002046845],"domain_scores_gemma":[0.9995656,0.000004256485,0.000060790037,0.0001459806,0.00006775178,0.00015560444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061452604,0.000111312234,0.0001197054,0.000043086162,0.00018158052,0.000046821573,0.00016527696,0.0000888369,0.00006753147],"category_scores_gemma":[0.000016000935,0.000077476696,0.000044407498,0.0000690869,0.000058130623,0.000011181451,0.00004370204,0.00019182822,0.0000024353337],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012663155,0.00002934625,0.00009479297,0.0000017203618,0.00002089972,0.0000042886586,0.0011137811,0.00009000606,0.99671614,0.000045272718,0.0005254585,0.0012316391],"study_design_scores_gemma":[0.0011313272,0.0012640257,0.000076942764,0.000025059542,0.000016119866,0.0002092883,0.0015333347,0.00012060489,0.9888729,0.00054077967,0.0060444996,0.00016511488],"about_ca_topic_score_codex":0.000023954766,"about_ca_topic_score_gemma":0.00006412872,"teacher_disagreement_score":0.00784326,"about_ca_system_score_codex":0.000019992032,"about_ca_system_score_gemma":0.000050692946,"threshold_uncertainty_score":0.3159408},"labels":[],"label_agreement":null},{"id":"W1025561166","doi":"10.1096/fasebj.27.1_supplement.1031.9","title":"The conformation of active receptor‐bound arrestin","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Arrestin; Chemistry; Receptor; Biophysics; Stereochemistry; G protein-coupled receptor; Biology; Biochemistry","score_opus":0.008972854878726639,"score_gpt":0.22352936677983154,"score_spread":0.2145565119011049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1025561166","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955612,0.000358497,0.002304143,0.0003387321,0.00032622088,0.000105814936,0.0000027896394,0.0000019852882,0.0010006136],"genre_scores_gemma":[0.9986263,0.00035452863,0.00018241114,0.000077890305,0.00026291359,0.0000053568274,0.000006636347,0.0000061300675,0.00047785943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994524,0.000077062934,0.000173461,0.000049292677,0.00011959478,0.00012815293],"domain_scores_gemma":[0.99948275,0.000029534698,0.00018076117,0.0001316568,0.00013494719,0.000040360002],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036445414,0.00006197205,0.000057136946,0.000010704581,0.00029757197,0.000052161216,0.00019842082,0.000043665877,0.00024162883],"category_scores_gemma":[0.000069247675,0.000031131778,0.000061757244,0.00003115564,0.000067877576,0.0000076257056,0.00003250991,0.00012512138,0.00002713675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029253657,0.0000052663863,0.00002576382,0.0000012318859,0.00002984458,7.3556635e-8,0.00013873473,0.000052817144,0.98287684,0.00015927342,0.0029581045,0.013722794],"study_design_scores_gemma":[0.00017043599,0.00010229007,0.00018209044,0.000009117081,0.0000066501975,0.000027747346,0.0010022112,0.00012281114,0.99016017,0.0008079064,0.007360861,0.00004773622],"about_ca_topic_score_codex":0.000014925545,"about_ca_topic_score_gemma":0.000002921123,"teacher_disagreement_score":0.013675058,"about_ca_system_score_codex":0.000008060133,"about_ca_system_score_gemma":0.00004733332,"threshold_uncertainty_score":0.26456663},"labels":[],"label_agreement":null},{"id":"W1029327045","doi":"","title":"Facilitatory Interactions Evidenced With the Multifocal ERG","year":2010,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Children's Hospital","funders":"","keywords":"Erg; Ophthalmology; Audiology; Neuroscience; Psychology; Medicine; Retina","score_opus":0.026742670672299823,"score_gpt":0.32831125265483185,"score_spread":0.301568581982532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1029327045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99788857,0.00003147383,0.00012957268,0.00061483384,0.00041600468,0.00018328696,0.000004516745,0.000012233685,0.0007195244],"genre_scores_gemma":[0.99696773,0.0000012669418,0.0020370595,0.00041285044,0.00012852106,0.000053342912,0.0000055737264,0.000010206855,0.00038342096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863774,0.00010432876,0.00014439078,0.0005217858,0.00024688485,0.00034486243],"domain_scores_gemma":[0.9991279,0.00007114481,0.00009374211,0.00029499995,0.00022510235,0.0001871115],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0006353282,0.00016352211,0.00011467579,0.0000536615,0.00054846547,0.000054212338,0.00051701756,0.000088427274,0.00018155227],"category_scores_gemma":[0.0004506084,0.00010221014,0.000046969722,0.00031092222,0.0040960233,0.000026873582,0.0001738925,0.0003514982,0.000034137913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025181136,0.000026016576,0.0020908264,0.0000016686785,0.000011303706,0.000009380457,0.00032961788,0.000028706858,0.9970222,0.00015380824,0.00011134453,0.00018992905],"study_design_scores_gemma":[0.00014202908,0.00051981857,0.0055323443,0.000009296004,0.000007176027,0.00021054318,0.0006383827,0.0002153577,0.9902742,0.00038401462,0.0019032664,0.0001635521],"about_ca_topic_score_codex":0.0000547491,"about_ca_topic_score_gemma":0.000037902944,"teacher_disagreement_score":0.0067479974,"about_ca_system_score_codex":0.000015323554,"about_ca_system_score_gemma":0.00034702529,"threshold_uncertainty_score":0.99861425},"labels":[],"label_agreement":null},{"id":"W1080346916","doi":"10.1021/jacs.5b06557","title":"Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR","year":2015,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Allosteric regulation; Chemistry; Affinities; Allosteric enzyme; Population; Stereochemistry; Biochemistry; Enzyme","score_opus":0.021075398805536313,"score_gpt":0.24913104565594169,"score_spread":0.22805564685040536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1080346916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973948,0.0008956299,0.0013564611,0.00020440684,0.000059740672,0.000052714902,0.0000031417687,0.000001101972,0.000032005802],"genre_scores_gemma":[0.9961195,0.00044395146,0.0032035394,0.00016778854,0.000048804373,6.2920594e-7,6.0332843e-7,0.000009223619,0.00000593923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989472,0.00007499638,0.0003205529,0.00010664592,0.0004083168,0.00014226328],"domain_scores_gemma":[0.9989549,0.000013294745,0.0006201887,0.00009765779,0.0002580091,0.000055967554],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006963102,0.00008661999,0.00022773775,0.000007645586,0.000015868198,0.0000113143715,0.00012636943,0.00004935716,0.0000019323588],"category_scores_gemma":[0.0001320639,0.00006342039,0.0001600102,0.00011457262,0.000087304645,0.0000054261996,0.00007301751,0.00014466484,1.2304993e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006518257,0.000032719407,0.0025918004,0.000005820751,0.00007452401,8.258021e-7,0.00028599543,0.0002746257,0.99583375,0.0000033204135,0.0005062134,0.0003252446],"study_design_scores_gemma":[0.0005521907,0.00012456405,0.0002604664,0.00003803006,0.000015437026,0.000008288074,0.0009454476,0.00005100605,0.99684143,0.00020154777,0.00088307547,0.00007852286],"about_ca_topic_score_codex":0.000013988362,"about_ca_topic_score_gemma":6.2521474e-7,"teacher_disagreement_score":0.0023313342,"about_ca_system_score_codex":0.00014978538,"about_ca_system_score_gemma":0.00008333505,"threshold_uncertainty_score":0.25862083},"labels":[],"label_agreement":null},{"id":"W108772770","doi":"10.71781/27146","title":"Etude des déterminants génétiques des psychoses à début précoce. Génétique de la schizophrénie et hypothèse glutamatergique","year":2011,"lang":"fr","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Génome Québec; Fondation Pierre Deniker pour la Recherche et la Prévention en Santé Mentale; Université Paris Descartes; Université de Montréal; Canadian Institutes of Health Research; Genome Canada","keywords":"Humanities; Biology; Philosophy; Molecular biology","score_opus":0.007073050573482931,"score_gpt":0.21489087250299335,"score_spread":0.20781782192951043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W108772770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9341052,0.04314305,0.0028933755,0.000030450308,0.00067606923,0.0003390478,0.00009526543,0.00006782487,0.018649694],"genre_scores_gemma":[0.93767685,0.02228676,0.017874412,0.00014794368,0.00029001047,0.00006664542,0.0007046452,0.00010510772,0.02084762],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99647796,0.0008452174,0.0005522456,0.0009880621,0.00036631912,0.0007701942],"domain_scores_gemma":[0.9978983,0.00009906582,0.0004898633,0.0005050995,0.00051628205,0.0004914157],"candidate_categories":["metaepi_narrow","sts","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0005798408,0.00075615925,0.0005588514,0.00021237945,0.004039368,0.00018490248,0.0006034839,0.0015113507,0.00013250626],"category_scores_gemma":[0.00017610642,0.0008815285,0.0005301048,0.0001951607,0.00076490804,0.00009541033,0.00024322486,0.0006056042,0.000020070267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013948514,0.00053644844,0.017504273,0.0005423791,0.0006210089,0.0019910198,0.024684578,0.0003713718,0.9349112,0.012742824,0.00013871958,0.0045613167],"study_design_scores_gemma":[0.0010637647,0.00038952826,0.02485661,0.0011837133,0.00031845563,0.0023818663,0.012715047,0.00012832157,0.9439381,0.0033326515,0.008693737,0.0009982063],"about_ca_topic_score_codex":0.016913023,"about_ca_topic_score_gemma":0.008772075,"teacher_disagreement_score":0.02085629,"about_ca_system_score_codex":0.0015031224,"about_ca_system_score_gemma":0.0028579559,"threshold_uncertainty_score":0.9997849},"labels":[],"label_agreement":null},{"id":"W11198567","doi":"10.1096/fasebj.22.1_supplement.831.1","title":"Phosphorylation and hetero‐oligomerization regulate the dopamine D3 receptor/adenylyl cyclase type 5 signaling complex","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"HEK 293 cells; Adenylyl cyclase; Heterotrimeric G protein; G protein-coupled receptor; Cell biology; Phosphorylation; Gs alpha subunit; Dopamine receptor D3; Signal transduction; Dopamine receptor; Chemistry; G protein; Receptor; Biology; Biochemistry","score_opus":0.02229479679780354,"score_gpt":0.23341332847831422,"score_spread":0.21111853168051067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W11198567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924212,0.0012727615,0.0055037886,0.00030992052,0.00028042216,0.00011315985,0.0000042567776,0.0000082532115,0.000086212654],"genre_scores_gemma":[0.9968919,0.0010800546,0.0006173578,0.00024604987,0.00059416675,0.0000023703865,0.000053358093,0.000020536068,0.0004942131],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991088,0.00013879169,0.00022905518,0.00015534507,0.00017842207,0.0001895761],"domain_scores_gemma":[0.99944913,0.000021795087,0.00016527886,0.00018279298,0.000107600456,0.000073372634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038702192,0.00013195068,0.000109457724,0.000026640164,0.00071536034,0.00006720711,0.00016892994,0.0000735904,0.00018509067],"category_scores_gemma":[0.00004601089,0.00007886769,0.00006287474,0.00009773497,0.00010975894,0.000009985916,0.000053468546,0.00017221154,0.000009163451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009199376,0.000010903134,0.00025655155,0.0000022971446,0.000035806766,0.00000308518,0.00017759441,0.0009462239,0.99679667,0.00003447325,0.0005618855,0.0010825044],"study_design_scores_gemma":[0.00039233777,0.00020345864,0.0006381233,0.000015722377,0.000023143357,0.00048853183,0.00016084699,0.001081256,0.9910867,0.0001323937,0.0056407647,0.00013667504],"about_ca_topic_score_codex":0.000006702448,"about_ca_topic_score_gemma":0.0000015288003,"teacher_disagreement_score":0.005709935,"about_ca_system_score_codex":0.0000135524615,"about_ca_system_score_gemma":0.000037305366,"threshold_uncertainty_score":0.5502046},"labels":[],"label_agreement":null},{"id":"W1187139979","doi":"","title":"An Easy and Automated Method for Estimating Receptor Parameters From A–Waves of the ERG","year":2006,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of Calgary","funders":"","keywords":"Erg; Computer science; Physics; Optics; Retina","score_opus":0.025767532540946055,"score_gpt":0.3409433497482726,"score_spread":0.31517581720732657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1187139979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943821,0.000062555315,0.0048955698,0.000051144587,0.00025341252,0.0002511927,0.000038747785,0.000018388302,0.000046930087],"genre_scores_gemma":[0.67819077,4.232492e-7,0.32162628,0.00005945583,0.00005503921,0.000019878386,0.000020132906,0.000008835281,0.00001917408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986009,0.00020529715,0.00024746382,0.00051655935,0.00016064876,0.00026915444],"domain_scores_gemma":[0.9992167,0.00010788976,0.00021622435,0.00021530356,0.0001456927,0.000098217126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006900383,0.00015203335,0.00018449695,0.00004050981,0.00028768403,0.000036797137,0.00036073278,0.000119265635,0.000013861569],"category_scores_gemma":[0.00046381427,0.00011270378,0.00005396974,0.00022582691,0.0015161408,0.000018940835,0.00012674995,0.00006973536,5.6118364e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017084038,0.000030513856,0.0026918561,0.0000054549446,0.0000109203165,5.6213764e-7,0.00009378083,0.00064491224,0.99603736,0.00014987988,0.000023115384,0.00029455737],"study_design_scores_gemma":[0.00018511247,0.0004686121,0.0056618266,0.000021783884,0.000012309912,0.000014568712,0.000097721124,0.049877603,0.93686795,0.006645921,0.0000144741425,0.00013210719],"about_ca_topic_score_codex":0.00042506552,"about_ca_topic_score_gemma":0.000004635781,"teacher_disagreement_score":0.3167307,"about_ca_system_score_codex":0.00001420535,"about_ca_system_score_gemma":0.00014764874,"threshold_uncertainty_score":0.5586284},"labels":[],"label_agreement":null},{"id":"W1193047888","doi":"10.1074/jbc.m115.644450","title":"β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Free fatty acid receptor 1; Arrestin; Heterotrimeric G protein; Signal transduction; G protein-coupled receptor; Cell biology; Agonist; G protein; Receptor; Functional selectivity; Biology; Internal medicine; Endocrinology; Chemistry; Biochemistry; Medicine","score_opus":0.08604263087196068,"score_gpt":0.2849544201652511,"score_spread":0.1989117892932904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1193047888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953645,0.0029220998,0.0006427659,0.0002711376,0.00022007202,0.000084572835,0.000020492966,0.000007308076,0.00046705318],"genre_scores_gemma":[0.9919658,0.0005525791,0.0061703655,0.0002007937,0.0007621462,0.00000785203,0.000047192814,0.000013579292,0.000279697],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989081,0.00006289084,0.00038207194,0.0002413943,0.00018457841,0.00022095484],"domain_scores_gemma":[0.9989647,0.000022821001,0.0002929466,0.00021868538,0.000160815,0.00034000026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000545991,0.00017732316,0.00025808168,0.000014186253,0.000059598944,0.000025261477,0.00027842674,0.00031363172,0.00023056737],"category_scores_gemma":[0.00063182047,0.00012299839,0.00013092218,0.00004444349,0.00009925935,0.000004234905,0.00024208856,0.00018274917,0.000005074234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028055417,0.000052249456,0.0011685133,0.000009656871,0.000039115617,0.000014686832,0.000021730182,0.000006803432,0.9921717,0.0000033036576,0.005024892,0.0012067962],"study_design_scores_gemma":[0.0010137997,0.0005499505,0.00018291225,0.000024580007,0.000012779958,0.000184503,0.0001046181,0.0000057238103,0.9583342,0.00026338696,0.039160747,0.00016278865],"about_ca_topic_score_codex":0.0000014753251,"about_ca_topic_score_gemma":4.374791e-7,"teacher_disagreement_score":0.034135856,"about_ca_system_score_codex":0.0000500155,"about_ca_system_score_gemma":0.00007279483,"threshold_uncertainty_score":0.5015729},"labels":[],"label_agreement":null},{"id":"W1202517771","doi":"10.1016/j.ymeth.2015.08.011","title":"RGS proteins destroy spare receptors: Effects of GPCR-interacting proteins and signal deamplification on measurements of GPCR agonist potency","year":2015,"lang":"en","type":"review","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Functional selectivity; Receptor; Heterotrimeric G protein; Signal transduction; Cell biology; G protein; Agonist; Biology; Ligand (biochemistry); Chemistry; Second messenger system; Biophysics; Biochemistry","score_opus":0.11048013968945261,"score_gpt":0.4064694492782405,"score_spread":0.2959893095887879,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1202517771","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00053180003,0.8721079,0.12373595,0.0000055518303,0.00045462875,0.0027757639,0.000028976721,0.000015581529,0.00034380052],"genre_scores_gemma":[0.0013153227,0.52149206,0.47508058,0.000015209543,0.0005129787,0.00071148516,0.0003936162,0.0001741603,0.0003045794],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99636215,0.0014861553,0.0008316082,0.000661541,0.00036544938,0.00029307115],"domain_scores_gemma":[0.99776936,0.00013330013,0.0011091933,0.0005233831,0.00032697612,0.00013779322],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0023346995,0.00047384907,0.0012520868,0.00013614124,0.00008280338,0.000032967462,0.000321698,0.0004845121,0.000030034673],"category_scores_gemma":[0.0009554256,0.00039500196,0.00033466893,0.00016733631,0.00007104129,0.000007660189,0.00013597101,0.00029289196,0.0000024376527],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038539692,0.000092657276,0.000005157756,0.0067930636,0.0001646719,8.0069736e-7,0.000040171664,0.0000036123486,0.30327597,0.000015742322,0.000040942403,0.68952864],"study_design_scores_gemma":[0.0003217294,0.0011348621,0.0000016961179,0.008167426,0.00036511853,0.000011898308,0.000026777945,0.0000070628644,0.7628033,0.00007555869,0.22669305,0.0003915129],"about_ca_topic_score_codex":0.00005881374,"about_ca_topic_score_gemma":0.000002541963,"teacher_disagreement_score":0.68913716,"about_ca_system_score_codex":0.00006833332,"about_ca_system_score_gemma":0.00029051898,"threshold_uncertainty_score":0.9998502},"labels":[],"label_agreement":null},{"id":"W1206829","doi":"10.1016/b978-0-12-408143-7.00009-8","title":"A Simple Method to Detect Allostery in GPCR Dimers","year":2013,"lang":"en","type":"article","venue":"Methods in cell biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Allosteric regulation; G protein-coupled receptor; Allosteric enzyme; Small molecule; Biology; Receptor; Allosteric modulator; Ligand (biochemistry); Biophysics; Drug discovery; Context (archaeology); Computational biology; Biochemistry","score_opus":0.02287507217559823,"score_gpt":0.364394333196249,"score_spread":0.3415192610206507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1206829","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43117377,0.00047034767,0.5661336,0.000083289764,0.00023185453,0.00039023836,0.0000036362437,0.000009780481,0.0015034612],"genre_scores_gemma":[0.22540562,0.000049859325,0.77315307,0.0008940333,0.00008344101,0.00014951594,0.000024865582,0.000025184245,0.00021441135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973297,0.001249621,0.00036201364,0.0005502363,0.000043331922,0.0004650586],"domain_scores_gemma":[0.99931073,0.00016959375,0.00006450171,0.00031847015,0.000034646557,0.000102074635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016476238,0.00019428614,0.00030925218,0.0001701139,0.000026579115,0.000014717698,0.0002731545,0.0003425566,0.0004247759],"category_scores_gemma":[0.00018920739,0.00017539227,0.00008716015,0.00021327974,0.000029985484,0.000003344787,0.00021298803,0.00017647154,0.00004008553],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024701283,0.000017951947,0.001064694,0.000007513899,0.0000075012354,0.0000015321692,0.000066093424,0.00018871103,0.89342755,0.000020306425,0.00012519186,0.105048254],"study_design_scores_gemma":[0.00036141128,0.0003372886,0.00042406993,0.0000051457278,0.000003644476,0.00000262837,0.00012327175,0.00033195489,0.96001375,0.0032125055,0.034953628,0.00023071759],"about_ca_topic_score_codex":0.0005172709,"about_ca_topic_score_gemma":0.00010012736,"teacher_disagreement_score":0.20701945,"about_ca_system_score_codex":0.000025418763,"about_ca_system_score_gemma":0.000033891076,"threshold_uncertainty_score":0.7152289},"labels":[],"label_agreement":null},{"id":"W12532119","doi":"10.1055/s-0037-1615769","title":"Serotonin 5-HT1 Receptors Potentiate Histamine and Thrombin Stimulated Prostaglandin Synthesis in Endothelial Cells","year":2001,"lang":"en","type":"article","venue":"Thrombosis and Haemostasis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Histamine; Prostaglandin; Endocrinology; Internal medicine; Prostaglandin D2; Agonist; Receptor; Serotonin; Prostaglandin E2 receptor; Thrombin; Chemistry; 5-HT receptor; Histamine receptor; Prostaglandin E; Biology; Medicine; Platelet","score_opus":0.024826977327185834,"score_gpt":0.263661221580971,"score_spread":0.23883424425378516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W12532119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99804467,0.0006183028,0.00025559688,0.0002048133,0.0001516563,0.00040231925,0.000069060625,0.000022313605,0.00023124885],"genre_scores_gemma":[0.99145633,0.0067020655,0.0011507962,0.000121898185,0.00007358206,0.00004584145,0.000056308127,0.000043947417,0.00034925735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984788,0.000104119485,0.0003262255,0.00054852676,0.0001505219,0.00039183488],"domain_scores_gemma":[0.9994504,0.000032267963,0.000100283396,0.00023609886,0.000044127395,0.00013682495],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00032401556,0.00027916406,0.00037591343,0.00010172459,0.0001479431,0.00007477851,0.000113621514,0.00021373083,0.00033625556],"category_scores_gemma":[0.000035720717,0.00025595783,0.000069011694,0.0001540623,0.00010493277,0.0000140808,0.00011826603,0.00011535462,0.0000062325894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016319711,0.00010725572,0.00903157,0.000033053373,0.00008074705,0.00000703469,0.00019838271,0.000033351997,0.9797454,0.000055631426,0.0004249469,0.010119464],"study_design_scores_gemma":[0.0014591697,0.00030123844,0.0063924105,0.00008508063,0.00006533736,0.000019447216,0.00027514165,0.000293728,0.98305947,0.0001151265,0.0075091254,0.00042472812],"about_ca_topic_score_codex":0.0002799172,"about_ca_topic_score_gemma":0.00009964083,"teacher_disagreement_score":0.0096947355,"about_ca_system_score_codex":0.00002476865,"about_ca_system_score_gemma":0.000027334872,"threshold_uncertainty_score":0.9999893},"labels":[],"label_agreement":null},{"id":"W126479704","doi":"","title":"Abstract 10257: Nuclear Angiotensin-II Receptor Gene Expression in Cardiac Fibroblasts: Receptor Subtype-Specific Differential Role of IP-3-Receptor (IP3R) Related and Nitric Oxide Signaling","year":2011,"lang":"en","type":"article","venue":"Circulation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Angiotensin II; Molecular biology; Gene expression; Receptor; Cytosol; Angiotensin II receptor type 1; Biology; Cell nucleus; Gene; Biochemistry","score_opus":0.011042856002946529,"score_gpt":0.19166128410470204,"score_spread":0.18061842810175552,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W126479704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969144,0.0016846266,0.0006289778,0.000007582804,0.00026648495,0.00031176026,0.000031078147,0.00002946998,0.00012564959],"genre_scores_gemma":[0.993859,0.00041435513,0.0050732857,0.000009483776,0.00018576394,0.000009676991,0.0003583059,0.000063878695,0.000026284968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822414,0.00012052086,0.00056609465,0.00055975415,0.00022155362,0.00030791276],"domain_scores_gemma":[0.9991023,0.000019598176,0.00030595824,0.00031917187,0.00013600996,0.00011698964],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027310866,0.00026554058,0.0003482151,0.00016849556,0.00014339211,0.000025565156,0.00014288224,0.00042851284,0.0007775028],"category_scores_gemma":[0.000047300582,0.00027156444,0.00017576473,0.00020436877,0.000064283005,0.000029581364,0.00010690011,0.00017803638,0.000024380857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002170713,0.000090252004,0.0040045585,0.000021113188,0.00004606747,4.765934e-7,0.00047043513,0.0001608633,0.9926212,0.00007176691,0.00014373318,0.0021524762],"study_design_scores_gemma":[0.00055828196,0.00008382285,0.05052929,0.00011323835,0.0000191616,0.0000018717661,0.000255314,0.00016281204,0.94631296,0.00012631253,0.001517961,0.0003189892],"about_ca_topic_score_codex":0.000045239656,"about_ca_topic_score_gemma":0.0000012261839,"teacher_disagreement_score":0.04652473,"about_ca_system_score_codex":0.000045641882,"about_ca_system_score_gemma":0.00003191885,"threshold_uncertainty_score":0.99997365},"labels":[],"label_agreement":null},{"id":"W1266868798","doi":"10.1016/j.ymeth.2015.08.018","title":"In vivo veritas, the next frontier for functionally selective GPCR ligands","year":2015,"lang":"en","type":"review","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"G protein-coupled receptor; In vivo; Computational biology; Receptor; Biology; Drug development; Drug discovery; Ligand (biochemistry); Translation (biology); Cell biology; Neuroscience; Signal transduction; Bioinformatics; Drug; Pharmacology; Biochemistry; Genetics","score_opus":0.10288012501185606,"score_gpt":0.4211176404289086,"score_spread":0.31823751541705253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1266868798","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000044395474,0.90264577,0.09487925,0.0000212457,0.0011134623,0.0006475936,0.000049714534,0.0000057808675,0.0006327706],"genre_scores_gemma":[9.69032e-7,0.9109919,0.08297131,0.0001468292,0.0011589285,0.00048417188,0.00013674368,0.0000632826,0.004045874],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998377,0.00043751308,0.00035557483,0.00045064982,0.000115979194,0.00026324863],"domain_scores_gemma":[0.9991858,0.00012100804,0.00017099507,0.0003251624,0.00013753158,0.00005950439],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023335316,0.00029777404,0.00074324926,0.000063718544,0.000074690026,0.00004413853,0.0003013281,0.0004551413,0.0000837899],"category_scores_gemma":[0.00022761163,0.00019673159,0.00041359293,0.00016053289,0.000032906755,0.000004302167,0.00009448162,0.00022141974,0.0000045345655],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036798738,0.000028207067,3.0897343e-7,0.0006143786,0.0002252337,8.624267e-7,0.00003581451,0.0000046638643,0.006632536,0.0001947218,0.03706825,0.95515823],"study_design_scores_gemma":[0.00019022723,0.00016812225,8.579638e-8,0.0002200081,0.00018358094,0.000011676167,0.000034472316,0.00001810407,0.00892292,0.0006262266,0.9893813,0.00024327872],"about_ca_topic_score_codex":0.000008517503,"about_ca_topic_score_gemma":0.0000057912484,"teacher_disagreement_score":0.9549149,"about_ca_system_score_codex":0.000054705102,"about_ca_system_score_gemma":0.00035202532,"threshold_uncertainty_score":0.8022481},"labels":[],"label_agreement":null},{"id":"W129790567","doi":"10.1007/978-1-60327-317-6_24","title":"A Quantum Dot-Labeled Ligand–Receptor Binding Assay for G Protein-Coupled Receptors Contained in Minimally Purified Membrane Nanopatches","year":2009,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Calgary","funders":"","keywords":"G protein-coupled receptor; Receptor; Biophysics; Chemistry; Streptavidin; Membrane; Ligand (biochemistry); Quantum dot; Membrane protein; Biochemistry; Nanotechnology; Biology; Biotin; Materials science","score_opus":0.01795633180823193,"score_gpt":0.3285931997800127,"score_spread":0.3106368679717808,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W129790567","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.71693873,0.0007716259,0.28004286,0.0003416464,0.0004028488,0.0013755878,0.000017829616,0.00003053589,0.00007836173],"genre_scores_gemma":[0.43179742,0.0001023139,0.56640875,0.00042975665,0.00014523673,0.00045439822,0.00033295027,0.000069186266,0.00026001336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956895,0.001319469,0.0008992375,0.0010628806,0.00013282704,0.0008960619],"domain_scores_gemma":[0.998814,0.00014485657,0.00028542953,0.00048137605,0.0001345815,0.00013977442],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0039383657,0.0004934724,0.00081244175,0.00035847278,0.000092946684,0.000042264994,0.00050003984,0.0008130711,0.000052798037],"category_scores_gemma":[0.0015614534,0.00047277068,0.00027569465,0.00042572463,0.00009735012,0.000008975659,0.00009811479,0.00031105886,0.0000055713226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007672445,0.00016875223,0.00017620198,0.00003443364,0.000059090347,0.000011069881,0.00009867125,0.00003646866,0.99037933,0.002124685,0.000023986468,0.006120076],"study_design_scores_gemma":[0.0028751495,0.0016957897,0.000019890525,0.00007439445,0.000019973688,0.0000068011977,0.00017339733,0.00058660697,0.9880238,0.0025978873,0.0033524998,0.0005737893],"about_ca_topic_score_codex":0.000042497286,"about_ca_topic_score_gemma":0.000034839675,"teacher_disagreement_score":0.2863659,"about_ca_system_score_codex":0.000082772814,"about_ca_system_score_gemma":0.00017171251,"threshold_uncertainty_score":0.99977237},"labels":[],"label_agreement":null},{"id":"W139711520","doi":"10.1007/bf03256212","title":"G-Protein-Coupled Receptors and Asthma Endophenotypes","year":2006,"lang":"en","type":"review","venue":"Molecular Diagnosis & Therapy","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; McGill University and Génome Québec Innovation Centre; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Endophenotype; G protein-coupled receptor; Receptor; Context (archaeology); Biology; Genetics; Neuroscience","score_opus":0.017469556788188127,"score_gpt":0.2723141025581204,"score_spread":0.25484454576993226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W139711520","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00563229,0.991835,0.0007952683,0.000024880106,0.00029103004,0.0011962609,0.000030056086,0.000038354006,0.00015686093],"genre_scores_gemma":[0.0004835006,0.9955445,0.0011686769,0.00017586829,0.00041468698,0.0010666521,0.0005763482,0.00021094036,0.0003588181],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973568,0.000292149,0.0005689418,0.0010065341,0.0002763374,0.00049923745],"domain_scores_gemma":[0.9987438,0.00003596368,0.00032800448,0.00066294475,0.000076642056,0.00015265298],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002845813,0.0007685464,0.0011741514,0.00014256858,0.00014009907,0.0001264123,0.0004177845,0.0007125823,0.00023428568],"category_scores_gemma":[0.000042632677,0.0006596589,0.00068373623,0.0002017651,0.00008737453,0.0000047778003,0.00014345115,0.000276874,0.000028205548],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000183669,0.0001174844,0.000004826974,0.00066725956,0.00040453498,0.00002596121,0.0000121267385,0.0000043279542,0.025048347,0.00022376169,0.001060177,0.9724128],"study_design_scores_gemma":[0.00039969874,0.00035534886,0.0000011482972,0.0009897167,0.0001042299,0.000017028657,0.0000047753415,0.0000019139868,0.03246443,0.000113521666,0.9648367,0.00071148184],"about_ca_topic_score_codex":0.00007549614,"about_ca_topic_score_gemma":0.000008362255,"teacher_disagreement_score":0.9717013,"about_ca_system_score_codex":0.000032620304,"about_ca_system_score_gemma":0.00012667917,"threshold_uncertainty_score":0.99958545},"labels":[],"label_agreement":null},{"id":"W141418178","doi":"10.1016/j.ddmod.2012.07.001","title":"GPCRs in cardiovascular pathologies","year":2012,"lang":"en","type":"article","venue":"Drug Discovery Today Disease Models","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont; University of Alberta","funders":"Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"Medicine; Diabetes mellitus; Blood pressure; Disease; Etiology; Obesity; Intensive care medicine; Cardiology; Internal medicine; Drug; Pharmacology; Endocrinology","score_opus":0.01461548673022922,"score_gpt":0.22476662547608378,"score_spread":0.21015113874585456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W141418178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.957394,0.019311722,0.021776717,0.000047487134,0.00031048356,0.00020592552,0.00006318038,0.000020894626,0.00086955994],"genre_scores_gemma":[0.9979615,0.00051146664,0.0002648213,0.00018659822,0.00028329622,0.00007220456,0.0001578613,0.000032264128,0.0005299779],"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986338,0.000115553295,0.0001975929,0.0003680266,0.00022417531,0.0004608356],"domain_scores_gemma":[0.99920547,0.000008129084,0.000037351077,0.0005282297,0.000024267447,0.0001965637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003797007,0.00020215573,0.00022136344,0.000054715216,0.000057848614,0.00004964363,0.00019138838,0.000079914214,0.000023373952],"category_scores_gemma":[0.000038399477,0.00018255562,0.00034870085,0.00007880281,0.000042526768,0.00005774826,0.00015366457,0.00008292953,0.000011657401],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010406891,0.0017840464,0.06498381,0.0003142747,0.00089591177,0.00015873324,0.0020177583,0.60529816,0.28185034,0.023146741,0.005572024,0.012937518],"study_design_scores_gemma":[0.009780469,0.0004077142,0.05827185,0.0006136072,0.0012473832,0.00005415456,0.0064672856,0.027194308,0.7398972,0.058219984,0.089464955,0.008381099],"about_ca_topic_score_codex":0.000030423049,"about_ca_topic_score_gemma":0.000004014079,"teacher_disagreement_score":0.57810384,"about_ca_system_score_codex":0.000023194692,"about_ca_system_score_gemma":0.0000612566,"threshold_uncertainty_score":0.74444026},"labels":[],"label_agreement":null},{"id":"W145264147","doi":"10.1007/978-94-007-4765-4_13","title":"GPCR and Voltage-Gated Calcium Channels (VGCC) Signaling Complexes","year":2012,"lang":"en","type":"review","venue":"Sub-cellular biochemistry/Subcellular biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"G protein-coupled receptor; Ion channel; Cell biology; Gating; Calcium signaling; Voltage-dependent calcium channel; Chemistry; Signal transduction; Biology; Biophysics; Receptor; Calcium; Biochemistry","score_opus":0.033826122173032575,"score_gpt":0.27142760327692084,"score_spread":0.23760148110388826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W145264147","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.027658815,0.9653353,0.0038360346,0.000016538284,0.00088134914,0.0011526354,0.00056454947,0.0001967561,0.0003580184],"genre_scores_gemma":[0.08219306,0.8887307,0.0008127394,0.000080305035,0.005103726,0.00027360787,0.017313497,0.0007877489,0.004704598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9910964,0.00028315993,0.002115331,0.0032506154,0.0009749951,0.002279535],"domain_scores_gemma":[0.9942563,0.00010036763,0.0014009231,0.002523363,0.00037798902,0.0013410203],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001196591,0.0028036027,0.0031297817,0.00024344506,0.00062765076,0.00043158513,0.0016875801,0.0037599783,0.0004208077],"category_scores_gemma":[0.00022456756,0.0028372207,0.0017921948,0.0006630739,0.0007002455,0.00002451401,0.0013150418,0.0014926199,0.0001358637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004543404,0.0002595562,0.0000040191594,0.012887865,0.00078457897,0.000079751706,0.000029420224,0.000004019448,0.9420813,0.000012911342,0.00092981226,0.042881347],"study_design_scores_gemma":[0.00054152065,0.000084552106,2.5338739e-8,0.0019794076,0.00091411656,0.0002610984,0.00006893656,0.000015213133,0.6269134,0.000016911417,0.36722654,0.0019782472],"about_ca_topic_score_codex":0.0000367901,"about_ca_topic_score_gemma":9.604045e-7,"teacher_disagreement_score":0.36629674,"about_ca_system_score_codex":0.0002573438,"about_ca_system_score_gemma":0.00079741236,"threshold_uncertainty_score":0.99846965},"labels":[],"label_agreement":null},{"id":"W1458428388","doi":"10.1016/j.biopsych.2015.07.026","title":"Regulator of G-Protein Signaling 7 Regulates Reward Behavior by Controlling Opioid Signaling in the Striatum","year":2015,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Regulator; Regulator of G protein signaling; Striatum; Signal transduction; Signaling proteins; Neuroscience; Cell biology; Chemistry; Biology; G protein; Dopamine; GTPase-activating protein; Gene; Biochemistry","score_opus":0.02549434382399065,"score_gpt":0.2567864192095815,"score_spread":0.23129207538559085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1458428388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99238497,0.0054127015,0.00093669543,0.00019602288,0.00041028956,0.00051742734,0.000030942683,0.000018166362,0.00009277123],"genre_scores_gemma":[0.9946226,0.000031509964,0.0044024833,0.0002399585,0.00044313856,0.00006957454,0.00011635207,0.00002027678,0.000054094617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99802655,0.00030302422,0.0005797812,0.00047049776,0.00024892492,0.00037125126],"domain_scores_gemma":[0.9991498,0.000036133417,0.00024523697,0.00035868367,0.00009570407,0.00011441763],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012389846,0.0002473674,0.00034385687,0.000046861413,0.000076960045,0.000033377517,0.00046640605,0.00040130707,0.000041853207],"category_scores_gemma":[0.00016109704,0.00016191136,0.00019324009,0.00017025057,0.00010450993,0.000006351933,0.00007336584,0.0002166521,0.0000040831674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026839797,0.0001671434,0.007551989,0.000010816923,0.000023374949,0.0000015648205,0.00005598239,0.000115930874,0.9900555,0.00066326745,0.0007947061,0.00029133682],"study_design_scores_gemma":[0.0031206263,0.0020400188,0.0010918169,0.00014178954,0.00005411026,0.000014127354,0.0021219174,0.000087078115,0.97900546,0.006590039,0.0050909864,0.00064206205],"about_ca_topic_score_codex":0.000028858705,"about_ca_topic_score_gemma":0.000005068493,"teacher_disagreement_score":0.011050061,"about_ca_system_score_codex":0.000016027085,"about_ca_system_score_gemma":0.00010233598,"threshold_uncertainty_score":0.6602554},"labels":[],"label_agreement":null},{"id":"W1459909004","doi":"10.1167/15.12.30","title":"Regulation of the expression of the cholinergic receptors in the visual cortex following long-term enhancement of visual cortical activity by cholinergic stimulation","year":2015,"lang":"en","type":"article","venue":"Journal of Vision","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Cholinergic; Basal forebrain; Stimulation; Visual cortex; Muscarinic acetylcholine receptor; Neuroscience; Nicotinic agonist; Cholinergic neuron; Psychology; Endocrinology; Receptor; Internal medicine; Medicine","score_opus":0.013865339157990696,"score_gpt":0.3144731003899308,"score_spread":0.3006077612319401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1459909004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99573094,0.00023835855,0.003346584,0.000058770827,0.00044341892,0.00016556565,0.0000014022579,6.8612394e-7,0.000014257723],"genre_scores_gemma":[0.99967873,0.00004621687,0.000104165585,0.000018911875,0.00010733276,0.0000012778364,0.0000065454387,0.000008896675,0.000027936578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99824697,0.00034880862,0.0005815111,0.00011975105,0.00059576565,0.000107206055],"domain_scores_gemma":[0.9987078,0.000042745167,0.0008360083,0.00018901665,0.00018595344,0.00003849659],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010728412,0.00010708214,0.00021632353,0.000042118812,0.00005009623,0.00000943282,0.00024657339,0.00012364674,0.000015736065],"category_scores_gemma":[0.00017663967,0.000053905107,0.00021904788,0.00015915907,0.000050742183,0.000021058646,0.00009026227,0.0001741355,1.1714416e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032251613,0.00030066897,0.008297757,0.000012612535,0.000014204411,2.5025838e-7,0.0001659277,0.0019827778,0.98740643,0.0000035618746,0.00012496836,0.0013683245],"study_design_scores_gemma":[0.0009000701,0.0006978368,0.098523356,0.00021456163,0.000031513522,0.0000037374575,0.000088854875,0.0016261158,0.8978035,0.000027244663,0.000028266339,0.000054965356],"about_ca_topic_score_codex":0.0000069331827,"about_ca_topic_score_gemma":0.0000025348152,"teacher_disagreement_score":0.0902256,"about_ca_system_score_codex":0.000028622128,"about_ca_system_score_gemma":0.00007923192,"threshold_uncertainty_score":0.21981865},"labels":[],"label_agreement":null},{"id":"W1481640451","doi":"10.1002/9780470627327.ch17","title":"Pharmacological Chaperones: Potential for the Treatment of Hereditary Diseases Caused by Mutations in G Protein‐Coupled Receptors","year":2010,"lang":"en","type":"other","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"G protein-coupled receptor; Rhodopsin; Receptor; Biology; Mutation; Genetics; Computational biology; Bioinformatics; Biochemistry; Gene","score_opus":0.009609328660693651,"score_gpt":0.2605307832462265,"score_spread":0.2509214545855329,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1481640451","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7632873,0.070760995,0.0904657,0.0018361399,0.012169225,0.03774665,0.007520503,0.00041516146,0.015798347],"genre_scores_gemma":[0.3435091,0.0046577337,0.0037513908,0.0001901162,0.003507864,0.004783895,0.006224263,0.0006777319,0.6326979],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991806,0.000032579992,0.00019889013,0.00030778264,0.00009662252,0.00018351804],"domain_scores_gemma":[0.9996093,0.000019669244,0.00011788849,0.00016934898,0.000028511382,0.00005526407],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000434289,0.00021608271,0.00023139763,0.000042560405,0.000045516397,0.000009410677,0.00014621286,0.00033589534,0.0033320675],"category_scores_gemma":[0.00001436477,0.00013194158,0.0001693668,0.00004000529,0.00007847559,0.0000010866642,0.000017744884,0.000058525755,0.0000022986637],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000098085045,0.000514662,0.000009263449,0.000024081628,0.0002608697,0.0000019856132,0.000020891928,0.00002745466,0.951923,0.000021210659,0.04407435,0.0030241462],"study_design_scores_gemma":[0.0027897705,0.001680405,0.000011210683,0.00003180926,0.0003133283,0.0000014541913,0.00021506756,0.0007164677,0.4683662,0.000050356113,0.52541846,0.00040544648],"about_ca_topic_score_codex":0.00018062635,"about_ca_topic_score_gemma":0.00018384267,"teacher_disagreement_score":0.61689955,"about_ca_system_score_codex":0.000012287018,"about_ca_system_score_gemma":0.000059729642,"threshold_uncertainty_score":0.99757904},"labels":[],"label_agreement":null},{"id":"W148403806","doi":"10.2310/6620.2008.06054","title":"Type I Allergy to Insulin: Case Report and Review of Localized and Systemic Reactions to Insulin","year":2008,"lang":"en","type":"article","venue":"Dermatitis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Insulin; Allergy; Dermatology; Internal medicine; Immunology","score_opus":0.01460537292871244,"score_gpt":0.2517062795163644,"score_spread":0.23710090658765193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W148403806","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96771777,0.02579456,0.004956473,0.0007660786,0.00013510314,0.00033351,0.00001931811,0.000010364452,0.00026685282],"genre_scores_gemma":[0.9550406,0.040062226,0.0026071134,0.0019755454,0.000049891933,0.000020359863,0.000040032337,0.000012066337,0.00019220513],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99930936,0.00003817757,0.0003020137,0.00018600372,0.00007233714,0.00009210774],"domain_scores_gemma":[0.9994797,0.000007663158,0.0000803262,0.00019701514,0.00012170785,0.00011360314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012029488,0.000085654145,0.0001828736,0.00003318361,0.0000609633,0.0000059117256,0.000037695707,0.00006263863,0.000026580454],"category_scores_gemma":[0.00016089692,0.000082097235,0.00002603951,0.00009729959,0.000018804862,0.00000332927,0.00005761754,0.000033918124,0.000005285719],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008161817,0.00014024532,0.0006041572,0.006567631,0.00035187035,0.017453972,0.0015272736,0.00011678728,0.8635428,0.0004992505,0.08832855,0.020785835],"study_design_scores_gemma":[0.0005914583,0.00042738806,0.00044494774,0.0024492014,0.000034511108,0.21047492,0.00012046214,0.000061288076,0.1742731,0.000034406243,0.6106985,0.00038976342],"about_ca_topic_score_codex":0.00023049834,"about_ca_topic_score_gemma":0.000029593859,"teacher_disagreement_score":0.6892697,"about_ca_system_score_codex":0.0000066354405,"about_ca_system_score_gemma":0.00003970951,"threshold_uncertainty_score":0.3347828},"labels":[],"label_agreement":null},{"id":"W1489894636","doi":"10.1111/bph.13253","title":"β‐Blockers have differential effects on the murine asthma phenotype","year":2015,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of Allergy and Infectious Diseases; University of Central Florida; National Institutes of Health; University of Texas MD Anderson Cancer Center; University of Florida; University of Pennsylvania","keywords":"Nadolol; Carvedilol; Alprenolol; Asthma; Ovalbumin; Bronchoconstriction; Medicine; Phenotype; Propranolol; Immunology; Sensitization; Pharmacology; Internal medicine; Biology; Immune system","score_opus":0.012443600755744083,"score_gpt":0.2603303310921929,"score_spread":0.2478867303364488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1489894636","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944295,0.0012177761,0.0013376713,0.0007632727,0.0018697182,0.000119435535,0.000004390176,0.0000037611553,0.00025446274],"genre_scores_gemma":[0.99606824,0.00023409874,0.00023271362,0.001084537,0.0021117611,0.0000051701772,0.00000600233,0.000018760067,0.00023871237],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999005,0.00023118797,0.00023582108,0.00013718069,0.00018019596,0.00021058065],"domain_scores_gemma":[0.99940413,0.000042663287,0.00018303789,0.000057473084,0.00017969254,0.0001330096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032713008,0.00011039287,0.00017810987,0.000033462267,0.00007560894,0.00003291458,0.00024966424,0.00009629431,0.00036829658],"category_scores_gemma":[0.00010119511,0.000091447364,0.00012589124,0.000035102417,0.000049309212,0.0000039389106,0.00006604232,0.00025459172,0.000009729555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030853724,0.000087519285,0.00002634718,0.00000677764,0.00014077539,0.00019972245,0.000030503985,0.000051490006,0.9009649,0.000041949737,0.08586436,0.012277095],"study_design_scores_gemma":[0.0020213542,0.0012707993,0.00011849663,0.000032678287,0.000047133068,0.00077331054,0.00006036049,0.00005715825,0.9607921,0.00019361891,0.03451546,0.00011749818],"about_ca_topic_score_codex":0.0000112862,"about_ca_topic_score_gemma":0.000005495855,"teacher_disagreement_score":0.05982721,"about_ca_system_score_codex":0.000019561834,"about_ca_system_score_gemma":0.00008103285,"threshold_uncertainty_score":0.40325892},"labels":[],"label_agreement":null},{"id":"W1490490649","doi":"10.1038/npp.2015.196","title":"Effects of β-Arrestin-Biased Dopamine D2 Receptor Ligands on Schizophrenia-Like Behavior in Hypoglutamatergic Mice","year":2015,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Mental Health; University of Toronto; North Carolina Biotechnology Center","keywords":"Dopamine receptor D2; Schizophrenia (object-oriented programming); Phencyclidine; Dopamine; Psychology; Pharmacology; Antipsychotic; Catalepsy; Functional selectivity; Neuroscience; Receptor; Haloperidol; Medicine; Internal medicine; G protein-coupled receptor; Psychiatry; NMDA receptor","score_opus":0.01320912025473398,"score_gpt":0.2709828332571006,"score_spread":0.2577737130023666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1490490649","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99581254,0.0004270049,0.000039557443,0.00009935101,0.002952022,0.00047910077,0.000013038368,0.000025346348,0.00015201689],"genre_scores_gemma":[0.99770606,0.00015729871,0.00043346325,0.00090030115,0.00037215542,0.00012436321,0.000039341056,0.00005542608,0.00021161386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99825865,0.00021439091,0.00040034406,0.00055542146,0.00019227645,0.00037893205],"domain_scores_gemma":[0.99919844,0.00007392665,0.00016943771,0.00024927518,0.00009847633,0.00021042518],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023535907,0.0002758289,0.0003282917,0.00017013955,0.000034231933,0.0000117786485,0.00031901067,0.00022034084,0.000083637635],"category_scores_gemma":[0.00011241658,0.0002692286,0.000103508675,0.00021786711,0.000077146186,0.0000054603684,0.000084306295,0.00024454697,0.000049336195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0023703587,0.00045296855,0.0005391536,0.000035844372,0.00002045647,0.00007706819,0.000037828126,0.000108576845,0.99249715,0.000012557678,0.0021754673,0.001672559],"study_design_scores_gemma":[0.0061137103,0.0021849514,0.0021607836,0.000024084033,0.000042097177,0.000021236576,0.000013908114,0.000053852553,0.9843801,0.000016154765,0.004742682,0.00024643698],"about_ca_topic_score_codex":0.000011689838,"about_ca_topic_score_gemma":0.0000037752152,"teacher_disagreement_score":0.008117059,"about_ca_system_score_codex":0.000021658832,"about_ca_system_score_gemma":0.00007914044,"threshold_uncertainty_score":0.999976},"labels":[],"label_agreement":null},{"id":"W1492554664","doi":"10.1023/a:1007131925048","title":"Modification of β-adrenoceptor signal transduction pathway by genetic manipulation and heart failure","year":2000,"lang":"en","type":"review","venue":"Molecular and Cellular Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Protein kinase C; Protein kinase A; Signal transduction; Adenylyl cyclase; Cell biology; G protein; Biology; Phosphorylation; Endoplasmic reticulum; Phospholamban; Biochemistry","score_opus":0.010832166244056769,"score_gpt":0.22988312874199673,"score_spread":0.21905096249793995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1492554664","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.046773955,0.94511575,0.007538697,0.000011504113,0.000036599715,0.00035620714,0.000112698406,0.000012205738,0.000042380674],"genre_scores_gemma":[0.16985387,0.82349193,0.0017389888,0.000031293173,0.00023936757,0.00008393913,0.0041936,0.00013122287,0.00023578148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981616,0.00010900211,0.00051549514,0.0007415089,0.00020011903,0.00027223545],"domain_scores_gemma":[0.99920356,0.0000070305173,0.00022207276,0.00036430446,0.00004965383,0.00015340302],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013363792,0.0004448396,0.00064097584,0.000056076675,0.00007838805,0.000042388092,0.00014607066,0.0007281736,0.0002129261],"category_scores_gemma":[0.0000069958696,0.00044642307,0.00028447772,0.00010264195,0.0001020331,0.0000042961674,0.000044017364,0.00018544342,0.0000019731485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009634045,0.000035801597,0.0000014052473,0.0023224978,0.000081287355,0.0000017862575,0.000006623511,0.0000041216936,0.89320636,0.000008061914,0.0001549939,0.10416745],"study_design_scores_gemma":[0.00016437436,0.00009108565,1.309086e-7,0.00042803166,0.00019021964,0.00005021742,0.000016227083,0.000011350325,0.79316044,0.000023542609,0.20551091,0.0003534456],"about_ca_topic_score_codex":0.000008345463,"about_ca_topic_score_gemma":2.4456187e-7,"teacher_disagreement_score":0.20535593,"about_ca_system_score_codex":0.000018100794,"about_ca_system_score_gemma":0.000092337235,"threshold_uncertainty_score":0.9997988},"labels":[],"label_agreement":null},{"id":"W1493369865","doi":"10.1111/j.1471-4159.2005.03476.x","title":"Opposing effects of phorbol‐12‐myristate‐13‐acetate, an activator of protein kinase C, on the signaling of structurally related human dopamine D1 and D5 receptors","year":2005,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Neurosciences Foundation; Canadian Psychiatric Research Foundation","keywords":"Protein kinase C; Activator (genetics); Bisindolylmaleimide; Receptor; Second messenger system; Signal transduction; Biology; Cell biology; HEK 293 cells; Dopamine receptor; Agonist; Dopamine; Protein kinase A; Endocrinology; Kinase; Biochemistry","score_opus":0.007536076883480193,"score_gpt":0.23047416528276277,"score_spread":0.22293808839928259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1493369865","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991699,0.0004124202,0.0000469842,0.00006496371,0.00007158659,0.0001600189,0.0000060368766,0.000003168542,0.00006495849],"genre_scores_gemma":[0.99896955,0.00006974352,0.0006815043,0.00002707138,0.00014412921,0.0000020455043,0.000008535652,0.00002924216,0.0000681559],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984823,0.00012274206,0.0007179471,0.0002130982,0.0002886701,0.00017525433],"domain_scores_gemma":[0.998275,0.00006116125,0.0010743542,0.00025434786,0.00022366398,0.000111503985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031646952,0.00021066931,0.0003703316,0.000054602995,0.00008077642,0.000020304658,0.00027915803,0.00015305993,0.00003766033],"category_scores_gemma":[0.00022155588,0.00015561857,0.00015449598,0.00008408403,0.00014127305,0.000017935512,0.00005704454,0.00029415102,7.691568e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002767371,0.00010648054,0.00007803755,0.00022818068,0.0000922492,0.000008938529,0.0001436907,0.00025349407,0.9975878,0.000015966583,0.000026512173,0.0011819294],"study_design_scores_gemma":[0.00083651755,0.0013061825,0.000256006,0.00035284174,0.000050129445,0.000056535453,0.00015582425,0.000034229073,0.9966203,0.00006972759,0.00012448459,0.00013721597],"about_ca_topic_score_codex":0.000004477059,"about_ca_topic_score_gemma":6.783876e-7,"teacher_disagreement_score":0.0011997019,"about_ca_system_score_codex":0.000014887871,"about_ca_system_score_gemma":0.0000764352,"threshold_uncertainty_score":0.6345941},"labels":[],"label_agreement":null},{"id":"W1507690397","doi":"10.1385/1-59259-430-1:121","title":"Green Fluorescent Protein-Tagged β-Arrestin Translocation as a Measure of G Protein-Coupled Receptor Activation","year":2003,"lang":"en","type":"review","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"G protein-coupled receptor; Rhodopsin-like receptors; Arrestin; Cell biology; G protein-coupled receptor kinase; Internalization; Heterotrimeric G protein; Biology; G protein; Chemistry; Receptor; Signal transduction; Biochemistry","score_opus":0.06054694606736133,"score_gpt":0.2950796783727313,"score_spread":0.23453273230536997,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1507690397","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005650384,0.9906412,0.001992131,0.0000038223448,0.0001391843,0.0050304867,0.000030676398,0.000035828845,0.0015616599],"genre_scores_gemma":[0.0020383664,0.9833036,0.0019978937,0.000030882555,0.0007024853,0.0029768196,0.00094032526,0.0002969999,0.0077126143],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972303,0.0004027979,0.0008442706,0.00073230505,0.00043787275,0.0003524915],"domain_scores_gemma":[0.99815273,0.000010539861,0.0007735142,0.00069102773,0.00025535526,0.00011682641],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004748214,0.0005626999,0.0009819301,0.0001138518,0.00012874449,0.00004365649,0.00043125043,0.0006910624,0.00008523507],"category_scores_gemma":[0.000078629455,0.0005047849,0.00047101892,0.000047573823,0.00007449961,0.0000057837838,0.000060760005,0.0003323956,0.0000074013174],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075262054,0.00007309891,1.4948665e-8,0.006528413,0.00027482383,9.946081e-7,0.000082793864,0.000002189024,0.29574215,0.0011739095,0.00006918432,0.69597715],"study_design_scores_gemma":[0.00037623697,0.0002228386,3.175855e-8,0.0060978523,0.00016131124,0.0000028601955,0.00000736141,0.000004843127,0.36383843,0.00005877419,0.6288109,0.00041855633],"about_ca_topic_score_codex":0.00022910403,"about_ca_topic_score_gemma":0.000016818798,"teacher_disagreement_score":0.6955586,"about_ca_system_score_codex":0.000052723706,"about_ca_system_score_gemma":0.00037351568,"threshold_uncertainty_score":0.99974036},"labels":[],"label_agreement":null},{"id":"W1512655005","doi":"10.1046/j.1471-4159.2001.00356.x","title":"Pharmacological and functional characterization of muscarinic receptor subtypes in developing oligodendrocytes","year":2001,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Medical Research Council; Multiple Sclerosis Society of Canada","keywords":"MAPK/ERK pathway; Cell biology; Muscarinic acetylcholine receptor; CREB; Biology; Signal transduction; Oligodendrocyte; Carbachol; Muscarinic acetylcholine receptor M3; Second messenger system; Receptor; Chemistry; Endocrinology; Biochemistry; Myelin; Transcription factor; Central nervous system","score_opus":0.017766605538549016,"score_gpt":0.24931156535432894,"score_spread":0.23154495981577994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1512655005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998514,0.00021472013,0.00094401225,0.000097217315,0.00014405746,0.000027127395,0.0000019014959,0.0000016165777,0.00005537343],"genre_scores_gemma":[0.99768364,0.001578729,0.00033038118,0.00010236062,0.00021471184,0.0000011800953,0.000014225322,0.0000073651154,0.00006741066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993463,0.000025160985,0.00030863463,0.00011679935,0.000106574465,0.000096486925],"domain_scores_gemma":[0.99957144,0.000013857787,0.00022441454,0.000045190052,0.00010025941,0.000044824737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013426288,0.0000814942,0.00013973315,0.000038233386,0.000019698622,0.000008746058,0.00007415095,0.00008950431,0.00016636084],"category_scores_gemma":[0.00006032503,0.000073687115,0.000049866314,0.00006926408,0.000025842808,0.000007700048,0.0000378842,0.000106559615,4.402558e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017227483,0.000032149354,0.0043770852,0.000017998573,0.000018393435,0.000008595694,0.000012443992,0.000017199054,0.99486107,0.0000075229996,0.00003550407,0.00043974945],"study_design_scores_gemma":[0.00043957293,0.00010976069,0.025435304,0.000029692199,0.000010590232,0.00020428353,0.000025695545,0.000020774745,0.9714104,0.000016385562,0.0022233604,0.00007418402],"about_ca_topic_score_codex":3.9890486e-7,"about_ca_topic_score_gemma":2.2906094e-7,"teacher_disagreement_score":0.023450688,"about_ca_system_score_codex":0.000010315027,"about_ca_system_score_gemma":0.000062104904,"threshold_uncertainty_score":0.30048734},"labels":[],"label_agreement":null},{"id":"W1516855418","doi":"10.1002/btpr.1706","title":"Cell‐free protein synthesis and purification of human dopamine D2 receptor long isoform","year":2013,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research","keywords":"Cell-free protein synthesis; Biochemistry; Receptor; Fusion protein; Biology; Dopamine; Chemistry; Protein biosynthesis; Recombinant DNA","score_opus":0.0077772739777715386,"score_gpt":0.21968369557773254,"score_spread":0.211906421599961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1516855418","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960365,0.0018998449,0.0006081821,0.0006490698,0.00004361478,0.0006042854,0.000009205004,0.00004807433,0.00010119814],"genre_scores_gemma":[0.992585,0.00013131055,0.0065805786,0.000010601448,0.000053538322,0.00030025843,0.000029267021,0.000023214381,0.0002862053],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903387,0.00003073819,0.00025000144,0.00035726224,0.000093117465,0.00023503703],"domain_scores_gemma":[0.99916416,0.0000054300845,0.0001792655,0.00051810214,0.00008520584,0.000047816546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015012783,0.0001569289,0.00018360929,0.00009354185,0.00009245504,0.000021277485,0.00033120537,0.0005259458,0.000112041875],"category_scores_gemma":[0.000058720165,0.00014096704,0.000047524452,0.000097001,0.00029760803,0.000007642714,0.00019718609,0.000104367646,0.000010774277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011431911,0.000074350326,0.00069366745,0.00006049883,0.000022540326,4.8451807e-7,0.00001017944,9.536991e-8,0.97532886,0.0007984124,0.00022642038,0.022773052],"study_design_scores_gemma":[0.00024026677,0.00038065022,0.0004929518,0.00003396395,0.000011841608,0.000004800591,0.0000856693,0.000011054084,0.99687773,0.0002526927,0.0014473523,0.00016101531],"about_ca_topic_score_codex":0.000019918883,"about_ca_topic_score_gemma":0.0000039035735,"teacher_disagreement_score":0.022612037,"about_ca_system_score_codex":0.00000870641,"about_ca_system_score_gemma":0.000016685468,"threshold_uncertainty_score":0.57484686},"labels":[],"label_agreement":null},{"id":"W1517177040","doi":"","title":"The succinate receptor GPR91 signals from the Endoplasmic Reticulum","year":2015,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Centre Hospitalier Universitaire Sainte-Justine; McGill University","funders":"","keywords":"Endoplasmic reticulum; Receptor; Cell biology; Chemistry; Biology; Biochemistry","score_opus":0.03558744891525649,"score_gpt":0.3076860769368402,"score_spread":0.2720986280215837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1517177040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952685,0.00061787333,0.00003297987,0.0013693022,0.0008718199,0.00026729523,0.000017507438,0.0000150323785,0.0015396765],"genre_scores_gemma":[0.9977183,0.000029660512,0.00074468204,0.0005568198,0.0003347446,0.000049799397,0.000019703102,0.000018496454,0.0005278475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975454,0.00044502888,0.00029723693,0.0006712525,0.00045737976,0.000583695],"domain_scores_gemma":[0.99843484,0.00022241432,0.00019828712,0.00045092497,0.00036390394,0.00032959916],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.001978114,0.00023607678,0.00018016848,0.000028579832,0.00087569456,0.00015197594,0.001135452,0.00014561591,0.00010317493],"category_scores_gemma":[0.0017513627,0.0001355581,0.0000788464,0.00040960955,0.0035194785,0.000021063095,0.00043681302,0.0002414805,0.000107773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039454953,0.000019950921,0.0025979502,6.4893186e-7,0.000021878495,0.000008944257,0.00032808885,0.000043517277,0.99512696,0.00036709962,0.0012497372,0.00019574242],"study_design_scores_gemma":[0.00025498695,0.0006054368,0.0014466705,0.0000137354455,0.000010502336,0.000053762917,0.0008464489,0.0002204777,0.9826589,0.008174545,0.005513577,0.00020091589],"about_ca_topic_score_codex":0.00018663696,"about_ca_topic_score_gemma":0.000011746365,"teacher_disagreement_score":0.0124680465,"about_ca_system_score_codex":0.00004231087,"about_ca_system_score_gemma":0.000586135,"threshold_uncertainty_score":0.99919236},"labels":[],"label_agreement":null},{"id":"W1517348949","doi":"10.1113/jphysiol.2011.222794","title":"G protein‐coupled receptor signalling in the cardiac nuclear membrane: evidence and possible roles in physiological and pathophysiological function","year":2011,"lang":"en","type":"review","venue":"The Journal of Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":137,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Intracrine; Receptor; Cell biology; Biology; Signal transduction; Nuclear receptor; Nuclear receptor coactivator 1; Second messenger system; Intracellular; Neuroscience; Paracrine signalling; Biochemistry","score_opus":0.04408593974312073,"score_gpt":0.2752950712686328,"score_spread":0.23120913152551206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1517348949","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.375201,0.62430394,0.0000115387675,0.000017817072,0.00008919567,0.00036776846,0.0000027377293,0.0000020856662,0.0000039199513],"genre_scores_gemma":[0.1604496,0.83890903,0.00010174165,0.000070474875,0.00040996177,0.000022831226,0.000008825068,0.000020741189,0.0000067989904],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967544,0.0018474208,0.00065528677,0.00033261874,0.00012128896,0.0002889651],"domain_scores_gemma":[0.9988366,0.0002222927,0.0005821956,0.00024157912,0.00006431205,0.00005305619],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016918898,0.00033365437,0.0011048324,0.000083712686,0.00010134302,0.000022386706,0.00047767136,0.00045629486,0.000042523217],"category_scores_gemma":[0.00017908186,0.00015736054,0.00026426907,0.00014387873,0.00021150649,0.000014556793,0.00019008826,0.0007488667,0.000003230972],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036029224,0.0000627179,0.000001517407,0.000528698,0.00007653738,0.0000025158963,0.0001554918,0.000019135647,0.97562224,0.0001265377,0.000030237956,0.023014063],"study_design_scores_gemma":[0.010487453,0.08135825,0.0118806325,0.099042445,0.008226602,0.0020115138,0.010749786,0.001113163,0.055586677,0.041188467,0.6673137,0.011041305],"about_ca_topic_score_codex":0.000015965414,"about_ca_topic_score_gemma":0.0000027818426,"teacher_disagreement_score":0.9200356,"about_ca_system_score_codex":0.00001650947,"about_ca_system_score_gemma":0.00007495846,"threshold_uncertainty_score":0.64169765},"labels":[],"label_agreement":null},{"id":"W1517379549","doi":"10.1096/fasebj.28.1_supplement.662.9","title":"Probing the structural determinants of the central region of third intracellular loop of human dopamine D1‐class receptor subtypes (662.9)","year":2014,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Ontario Mental Health Foundation","keywords":"Agonist; G protein-coupled receptor; Receptor; Intracellular; Biology; Cell biology; Dopaminergic; Transmembrane domain; Dopamine receptor; Dopamine; Biochemistry; Neuroscience","score_opus":0.011557661879150962,"score_gpt":0.22812500876304054,"score_spread":0.21656734688388957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1517379549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99865377,0.00029631722,0.00040115652,0.00010610414,0.00032731227,0.00014061487,0.0000046802083,0.0000017985371,0.000068250156],"genre_scores_gemma":[0.9993187,0.00006473373,0.00008999772,0.00002637114,0.00030121458,0.0000012989044,0.0000035180374,0.000013991193,0.00018014593],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987476,0.00027365066,0.0004207562,0.00011974447,0.00021821908,0.00022003299],"domain_scores_gemma":[0.9988229,0.0000283539,0.00062373106,0.00035175376,0.00013173126,0.00004148971],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062836276,0.00012881824,0.0002038771,0.000021195101,0.00022335106,0.000017807659,0.00055006036,0.00008699593,0.000041036863],"category_scores_gemma":[0.000081876686,0.000059934784,0.00018657367,0.000070823684,0.00021807382,0.0000063019,0.00010543666,0.00020655229,3.3897027e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000641426,0.000013989347,0.0035950355,0.000022858525,0.000038842114,5.4906e-7,0.00024718922,0.00013379875,0.99385715,0.00019506861,0.00007015074,0.0017612224],"study_design_scores_gemma":[0.00031304773,0.0002761356,0.0012014781,0.0000876585,0.000042321266,0.000086624306,0.00029601651,0.00033015673,0.9968647,0.00027713698,0.00014829276,0.00007647202],"about_ca_topic_score_codex":0.000024640904,"about_ca_topic_score_gemma":0.000016090404,"teacher_disagreement_score":0.0030075065,"about_ca_system_score_codex":0.0000104529945,"about_ca_system_score_gemma":0.000049835347,"threshold_uncertainty_score":0.24440697},"labels":[],"label_agreement":null},{"id":"W1519239048","doi":"10.1016/s0079-6123(03)45012-7","title":"Cholinergic modulation of the cortical microvascular bed","year":2004,"lang":"en","type":"review","venue":"Progress in brain research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Basal forebrain; Neuroscience; Cholinergic; Cholinergic neuron; Acetylcholine; Cerebral cortex; Biology; Anatomy; Endocrinology","score_opus":0.07738002741538352,"score_gpt":0.4226476684996199,"score_spread":0.34526764108423635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1519239048","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0055612386,0.99319315,0.000052727533,0.000059389644,0.00011285265,0.000964925,0.000008380822,0.0000038781172,0.00004347016],"genre_scores_gemma":[0.016575187,0.9821468,0.0004915548,0.00000906522,0.00019996923,0.00022967026,0.0001226816,0.00005415988,0.00017090866],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997143,0.0009158333,0.00049998873,0.00047475638,0.00054976065,0.0004166885],"domain_scores_gemma":[0.99890196,0.00008036795,0.00013274804,0.00065432914,0.0001706934,0.000059900838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021826574,0.00020498254,0.0005385533,0.00015754199,0.00009319645,0.00003288839,0.00067405036,0.00047845067,0.000034556037],"category_scores_gemma":[0.00040268968,0.00013702117,0.00040046728,0.00051053637,0.00031634135,0.000002127733,0.000425434,0.0007046741,0.0000050170825],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027150509,0.00024428344,0.00018862687,0.010376198,0.00016512681,0.000009986956,0.00005621632,0.0000771158,0.0058654193,0.00104837,0.00015770401,0.9817838],"study_design_scores_gemma":[0.0010558233,0.0003623555,0.00019485124,0.016136475,0.00009347605,0.000045314657,0.000037005335,0.00017321503,0.01821639,0.0008321098,0.9622103,0.0006426962],"about_ca_topic_score_codex":0.000011925731,"about_ca_topic_score_gemma":0.000005936374,"teacher_disagreement_score":0.9811411,"about_ca_system_score_codex":0.000068083435,"about_ca_system_score_gemma":0.0004722478,"threshold_uncertainty_score":0.5587561},"labels":[],"label_agreement":null},{"id":"W1528161850","doi":"10.3389/fphar.2015.00131","title":"Comparative analyses of downstream signal transduction targets modulated after activation of the AT1 receptor by two β-arrestin-biased agonists","year":2015,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Arrestin; G protein-coupled receptor; Functional selectivity; Signal transduction; Receptor; G protein; Cell biology; Angiotensin II receptor type 1; Angiotensin II; Chemistry; Gq alpha subunit; Phosphorylation; Effector; Biology; Biochemistry","score_opus":0.02754999804281991,"score_gpt":0.317609123997926,"score_spread":0.2900591259551061,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1528161850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9804424,0.0007806118,0.017247185,0.00007940403,0.0010561957,0.0002689392,0.000047874822,0.0000049541063,0.00007240376],"genre_scores_gemma":[0.9973102,0.000035450892,0.002232442,0.00006789577,0.00009965701,0.000034605353,0.00012543514,0.000010972449,0.00008333547],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988479,0.0002776493,0.00032082602,0.00024276703,0.0001373904,0.00017345275],"domain_scores_gemma":[0.9994571,0.000011243918,0.00021333176,0.00011708476,0.00014316721,0.000058053414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019130863,0.00014209685,0.00028657055,0.0000709607,0.000028639995,0.000003837318,0.00016113077,0.00012728799,0.00018854091],"category_scores_gemma":[0.000015481992,0.000116320465,0.000092626105,0.00019640838,0.00015326016,0.00000924039,0.000029428424,0.0001142955,5.930894e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008938954,0.00013966426,0.0017958079,0.00001065701,0.00014544978,3.694791e-7,0.00028762038,0.0070669274,0.97195524,9.691004e-7,0.017160652,0.00054274447],"study_design_scores_gemma":[0.0015346084,0.00020375254,0.00023117621,0.000012334198,0.00005239784,9.369891e-7,0.0002090147,0.0027358064,0.9927649,0.00006998899,0.0020720395,0.00011302775],"about_ca_topic_score_codex":0.000069288486,"about_ca_topic_score_gemma":0.000004578663,"teacher_disagreement_score":0.020809675,"about_ca_system_score_codex":0.00004129404,"about_ca_system_score_gemma":0.000093699964,"threshold_uncertainty_score":0.4743411},"labels":[],"label_agreement":null},{"id":"W1530043812","doi":"10.1111/j.1471-4159.2006.04364.x","title":"Purification of visual arrestin from squid photoreceptors and characterization of arrestin interaction with rhodopsin and rhodopsin kinase","year":2007,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Arrestin; Rhodopsin; Biology; GTP'; Visual phototransduction; Biochemistry; Cell biology; Protein kinase A; Kinase; Signal transduction; G protein-coupled receptor; Retinal; Enzyme","score_opus":0.008077025814262728,"score_gpt":0.2442432143965001,"score_spread":0.23616618858223737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1530043812","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945724,0.00014605417,0.005034505,0.00002197223,0.00012876013,0.00005600513,0.0000122365045,0.000002243181,0.000025826104],"genre_scores_gemma":[0.9976453,0.00012428177,0.0019120355,0.000019115676,0.00021346741,7.235643e-7,0.000054877957,0.000015303202,0.000014894045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999089,0.000034796034,0.0004476635,0.00016915277,0.00016086009,0.00009851478],"domain_scores_gemma":[0.9988316,0.000040144387,0.00073838443,0.000098495984,0.00020469626,0.00008664147],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025387492,0.00012282262,0.00019540505,0.000052711508,0.000026390253,0.000014964349,0.000075479766,0.0001046988,0.000023036939],"category_scores_gemma":[0.0001253715,0.00010858579,0.00004138486,0.00006924344,0.00006849198,0.000015856658,0.00002608169,0.00012472006,7.5716294e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007104611,0.0000766509,0.0029755898,0.000048626687,0.000027087586,0.0000055933074,0.00007382826,0.000007938406,0.99346775,0.0000016152221,0.000009181222,0.0025957022],"study_design_scores_gemma":[0.0004927001,0.0004508067,0.016996138,0.00012882227,0.000034111818,0.000074859505,0.00017111648,0.00005843587,0.9812604,0.000009393007,0.00022990249,0.00009329139],"about_ca_topic_score_codex":0.000008056413,"about_ca_topic_score_gemma":0.0000014292988,"teacher_disagreement_score":0.014020547,"about_ca_system_score_codex":0.0000086458585,"about_ca_system_score_gemma":0.0000417439,"threshold_uncertainty_score":0.4428},"labels":[],"label_agreement":null},{"id":"W1530059721","doi":"10.1523/jneurosci.21-21-08378.2001","title":"Agonist-Induced Internalization of Serotonin-1A Receptors in the Dorsal Raphe Nucleus (Autoreceptors) But Not Hippocampus (Heteroreceptors)","year":2001,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Medical Research Council; Canadian Institutes of Health Research; Medical Research Council Canada","keywords":"Dorsal raphe nucleus; Neuroscience; Autoreceptor; Internalization; Hippocampus; Agonist; Serotonin; Raphe nuclei; Receptor; Biology; Serotonergic","score_opus":0.02242489883055341,"score_gpt":0.2678999997428844,"score_spread":0.24547510091233102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1530059721","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931232,0.00008714419,0.0044407924,0.00016826148,0.0018309613,0.00022521867,0.0000037388606,0.000004816226,0.00011589224],"genre_scores_gemma":[0.9983307,0.00033552953,0.00035702216,0.00063896785,0.00023615031,0.000007165247,0.0000029343319,0.000021397784,0.00007014622],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99781483,0.00027734652,0.00071391073,0.000303428,0.00057672145,0.000313765],"domain_scores_gemma":[0.9987115,0.000039454426,0.0006805173,0.00028555188,0.00019323225,0.000089727786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010081977,0.00020307077,0.00026955566,0.00017567523,0.00010531421,0.00008294037,0.00091404776,0.00013417941,0.00006482568],"category_scores_gemma":[0.0002967445,0.0001456036,0.00020773409,0.00043537965,0.00014568656,0.000040805797,0.00009428066,0.0002861197,0.0000024017154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002191535,0.000120664365,0.0023332143,0.000007796656,0.000006237856,0.000016989523,0.00026960857,0.000280288,0.99238485,0.0000626392,0.00019340165,0.004105178],"study_design_scores_gemma":[0.0007805037,0.001973033,0.002505438,0.00008767836,0.000015686535,0.00032922125,0.00035566525,0.00038056422,0.9728552,0.00015202348,0.020342551,0.00022239944],"about_ca_topic_score_codex":0.000023286922,"about_ca_topic_score_gemma":0.0000075469047,"teacher_disagreement_score":0.02014915,"about_ca_system_score_codex":0.00003127525,"about_ca_system_score_gemma":0.00012082399,"threshold_uncertainty_score":0.59375423},"labels":[],"label_agreement":null},{"id":"W1532593543","doi":"10.1111/j.1432-1033.2004.04390.x","title":"The role of helix 8 and of the cytosolic C‐termini in the internalization and signal transduction of B<sub>1</sub> and B<sub>2</sub> bradykinin receptors","year":2004,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Internalization; Receptor; Chimera (genetics); G protein-coupled receptor; Bradykinin receptor; Biology; Molecular biology; Signal transduction; Mutant; Serine; Biochemistry; Bradykinin; Cell biology; Phosphorylation; Gene","score_opus":0.0044801046216020055,"score_gpt":0.20091591202121575,"score_spread":0.19643580739961375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1532593543","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955641,0.002309189,0.0017440701,0.00012527296,0.00011295392,0.000119582124,0.00000586098,9.319916e-7,0.000018046354],"genre_scores_gemma":[0.9966588,0.0031242112,0.000047459915,0.000032540618,0.000119733166,0.0000028819552,0.0000024901071,0.000010054186,0.0000018506688],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990956,0.00014713184,0.00034124125,0.00012581181,0.00016501507,0.00012516518],"domain_scores_gemma":[0.9994895,0.000024446877,0.00027261314,0.00010991244,0.00006830406,0.000035225454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005286234,0.0001052236,0.00014078115,0.0000426521,0.00011880665,0.00003103568,0.00014121481,0.00009155129,0.000003052079],"category_scores_gemma":[0.000034570898,0.0000603903,0.0000647609,0.00008835044,0.00016240482,0.000012907417,0.000039492472,0.00014915982,5.9599365e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009758698,0.000025852123,0.0016329122,0.000014639467,0.000027902237,4.47645e-7,0.0009542812,0.000114409435,0.9797586,0.00013800853,0.00000927417,0.017226042],"study_design_scores_gemma":[0.00055221474,0.00030973816,0.0029640228,0.000102565,0.000025121808,0.0001608785,0.00071871805,0.000060102666,0.99289334,0.0019995384,0.00014911885,0.00006466809],"about_ca_topic_score_codex":0.000012448066,"about_ca_topic_score_gemma":0.000044785113,"teacher_disagreement_score":0.017161373,"about_ca_system_score_codex":0.00000784145,"about_ca_system_score_gemma":0.0000494185,"threshold_uncertainty_score":0.24626449},"labels":[],"label_agreement":null},{"id":"W1534600986","doi":"10.3389/fnana.2011.00058","title":"Role of beta-arrestin 2 downstream of dopamine receptors in the basal ganglia","year":2011,"lang":"en","type":"article","venue":"Frontiers in Neuroanatomy","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"G protein-coupled receptor; G protein-coupled receptor kinase; Biology; Dopamine; Arrestin; Dopamine receptor D2; Neuroscience; Dopamine receptor; Signal transduction; Cell biology; Receptor; Dopaminergic; Biochemistry","score_opus":0.009177531190561016,"score_gpt":0.20808807653239805,"score_spread":0.19891054534183703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1534600986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99572355,0.00092388765,0.0006336957,0.0000243962,0.00037932064,0.00018418845,0.0000075904745,0.000003489185,0.0021198923],"genre_scores_gemma":[0.9963082,0.00011239816,0.0033526665,0.000082498686,0.0000399322,0.000014367583,0.00001572075,0.00001640653,0.00005782269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895954,0.00013527194,0.00033207668,0.00023496614,0.00014558776,0.0001925674],"domain_scores_gemma":[0.9994786,0.000011512959,0.00013208225,0.00030830968,0.000038210746,0.000031289936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029701585,0.00012850946,0.0002201097,0.000117639735,0.000014747155,0.0000037181285,0.00035617177,0.0001015254,0.00005467825],"category_scores_gemma":[0.000060862483,0.000100990284,0.00008598316,0.00022002064,0.00008583829,0.000004936529,0.00005406669,0.0001219563,6.657931e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004603489,0.0006120269,0.31692788,0.0000750007,0.00009083285,0.000025084451,0.0019219457,0.0001336118,0.6323137,0.00052794756,0.01169054,0.035221063],"study_design_scores_gemma":[0.0006406507,0.0003157013,0.006616689,0.000025864698,0.000018291985,0.0000021583182,0.0014462827,0.00018274585,0.98411953,0.0013971957,0.005068184,0.00016672577],"about_ca_topic_score_codex":0.00012485134,"about_ca_topic_score_gemma":0.000029312176,"teacher_disagreement_score":0.3518058,"about_ca_system_score_codex":0.0000062440463,"about_ca_system_score_gemma":0.000033346543,"threshold_uncertainty_score":0.41182643},"labels":[],"label_agreement":null},{"id":"W153683884","doi":"10.1096/fasebj.24.1_supplement.904.1","title":"Defining the mechanisms by which palmitoylation regulates the localization and function of RGS4","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Heart and Stroke Foundation; University of Toronto","funders":"","keywords":"Palmitoylation; HEK 293 cells; Heterotrimeric G protein; Cell biology; Transfection; G protein; Biology; Chemistry; Signal transduction; Biochemistry; Cysteine; Receptor; Gene; Enzyme","score_opus":0.004163905492677171,"score_gpt":0.20141493918058337,"score_spread":0.1972510336879062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W153683884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87716377,0.00084012444,0.12095186,0.0004618644,0.00038068352,0.00008551295,0.0000035382054,0.000003228764,0.000109392124],"genre_scores_gemma":[0.99921507,0.0001499844,0.00021054615,0.00014574625,0.00017511992,0.0000026585633,0.000017769364,0.00000953847,0.00007355272],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994252,0.00009876991,0.00015610842,0.00008636265,0.00013302153,0.000100544],"domain_scores_gemma":[0.99951667,0.00003174181,0.00016072913,0.00015633204,0.00010890629,0.000025638266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000814619,0.000073019146,0.000057285026,0.000012007934,0.00043144496,0.000059638554,0.00013517392,0.00007859726,0.000054211305],"category_scores_gemma":[0.00006872236,0.000033756696,0.000036263038,0.000067225206,0.00005269275,0.0000058807577,0.000035934627,0.00019241717,0.0000010923799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002961549,0.0000051062566,0.00013519118,0.0000016788659,0.000023474686,5.6558573e-8,0.00009433597,0.00035245658,0.99175197,0.003879593,0.00038475168,0.0033417593],"study_design_scores_gemma":[0.00016190637,0.00011696926,0.00023829608,0.0000077389805,0.00003539914,0.000052208947,0.0003816213,0.0022693318,0.98952115,0.005842444,0.0013205586,0.00005240185],"about_ca_topic_score_codex":0.00000798059,"about_ca_topic_score_gemma":0.000020389749,"teacher_disagreement_score":0.12205129,"about_ca_system_score_codex":0.000002560089,"about_ca_system_score_gemma":0.00002555962,"threshold_uncertainty_score":0.33183694},"labels":[],"label_agreement":null},{"id":"W153758526","doi":"10.1007/978-94-007-4765-4_2","title":"Role of Chaperones in G Protein Coupled Receptor Signaling Complex Assembly","year":2012,"lang":"en","type":"review","venue":"Sub-cellular biochemistry/Subcellular biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Dalhousie Medical Research Foundation","keywords":"G protein-coupled receptor; Receptor; Signal transduction; Cell biology; Biology; Cell signaling; G protein; Computational biology; Chemistry; Biochemistry","score_opus":0.023463987409372146,"score_gpt":0.2565341746551674,"score_spread":0.23307018724579529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W153758526","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15937589,0.8378766,0.0003479291,0.000008120064,0.00020167946,0.0014049874,0.00032544418,0.000069851056,0.00038949214],"genre_scores_gemma":[0.258323,0.7185842,0.002259622,0.000023444969,0.0021739905,0.0007033375,0.015418698,0.0006825106,0.0018312361],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99179965,0.00034247173,0.0026722075,0.0023892422,0.0010089773,0.0017874566],"domain_scores_gemma":[0.9947125,0.000069043344,0.0018849106,0.002316042,0.00035193306,0.00066561863],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0013673375,0.0021017839,0.0032313373,0.0002957022,0.0002059464,0.00011571132,0.00190949,0.003131381,0.00055820553],"category_scores_gemma":[0.00024366955,0.0021986659,0.0018018549,0.0008553525,0.0004322921,0.000019881914,0.00080606295,0.0011742762,0.00009112145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075694494,0.0005638417,0.000007119547,0.012947864,0.00040403963,0.000017915543,0.00003144954,0.0000059386666,0.9575882,0.0000157364,0.0000838112,0.028258404],"study_design_scores_gemma":[0.0007539825,0.00012033565,1.1564385e-7,0.0040900097,0.00038666435,0.000048907244,0.00015376126,0.000052537383,0.827526,0.0000146743005,0.16503838,0.0018146621],"about_ca_topic_score_codex":0.00005326997,"about_ca_topic_score_gemma":0.0000038612516,"teacher_disagreement_score":0.16495457,"about_ca_system_score_codex":0.00031444503,"about_ca_system_score_gemma":0.0010624229,"threshold_uncertainty_score":0.99917233},"labels":[],"label_agreement":null},{"id":"W1539231406","doi":"10.1016/s0076-6879(02)43124-2","title":"Considerations in the evaluation of inverse agonism and protean agonism at G protein-coupled receptors","year":2002,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"American Society for Pharmacology and Experimental Therapeutics; Heart and Stroke Foundation of Canada","keywords":"Agonism; G protein-coupled receptor; Inverse agonist; Functional selectivity; Receptor; Agonist; Chemistry; Pharmacology; Biology; Biochemistry; Political science","score_opus":0.09479403400188162,"score_gpt":0.39899083466572427,"score_spread":0.30419680066384264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1539231406","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9801417,0.0018065708,0.012930412,0.0007461129,0.00074740226,0.0023433855,0.000008852096,0.000018669512,0.0012569012],"genre_scores_gemma":[0.48731336,0.0001667268,0.5106344,0.0006749631,0.000098805045,0.0008354984,0.0000268302,0.000046313562,0.0002031103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.97836673,0.018137682,0.0012751808,0.001131546,0.00034597423,0.0007428765],"domain_scores_gemma":[0.9968986,0.0014958294,0.00047180435,0.0008575314,0.0001826337,0.00009360902],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.019019311,0.00047951273,0.00086848263,0.0006011952,0.00017639392,0.00002305165,0.00042694242,0.0010552177,0.00083926343],"category_scores_gemma":[0.005901986,0.00042024037,0.0001504094,0.00050352275,0.0006669905,0.000018232138,0.0002636703,0.0008333139,0.0000071230847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001361524,0.00035931682,0.0011351623,0.000034789893,0.0000498644,0.000030866708,0.0019751994,0.00093088363,0.9734712,0.003710806,0.00020010403,0.017965624],"study_design_scores_gemma":[0.0072527933,0.0027833723,0.017545156,0.00014195846,0.00013400152,0.0005463285,0.0015523651,0.007717971,0.87193877,0.085393555,0.0038428267,0.0011509182],"about_ca_topic_score_codex":0.0002264419,"about_ca_topic_score_gemma":0.0016040858,"teacher_disagreement_score":0.49770397,"about_ca_system_score_codex":0.00016914983,"about_ca_system_score_gemma":0.00012817618,"threshold_uncertainty_score":0.99982494},"labels":[],"label_agreement":null},{"id":"W1541640449","doi":"10.1111/bph.12761","title":"Prolonged morphine treatment alters δ opioid receptor post‐internalization trafficking","year":2014,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Internalization; DAMGO; Agonist; Receptor; Opioid receptor; Pharmacology; μ-opioid receptor; Chemistry; Opioid; Cell biology; Endocrinology; Biology; Biochemistry","score_opus":0.0077440339199895515,"score_gpt":0.2546726949725561,"score_spread":0.24692866105256658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1541640449","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9794585,0.0016729841,0.016998066,0.00024550353,0.0014098219,0.00013769015,0.0000099057115,0.000007690861,0.000059808335],"genre_scores_gemma":[0.9946206,0.0014426229,0.0014000606,0.00066561816,0.0016264389,0.0000077824225,0.000043805307,0.000026254418,0.00016680881],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988978,0.00019089832,0.00038605055,0.0001843662,0.0001220992,0.00021879164],"domain_scores_gemma":[0.9992846,0.000016812826,0.0003132506,0.000049688024,0.00023132,0.000104299004],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036435112,0.00013033453,0.0002313939,0.0000635224,0.000081032544,0.000038428658,0.00018063272,0.00010608597,0.0005705106],"category_scores_gemma":[0.000054444117,0.00013524762,0.00016351367,0.000046821733,0.000038109487,0.000010404528,0.000028822946,0.000116129406,0.0000056309677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021778072,0.00012360186,0.000083466024,0.000008944737,0.00014785187,0.000035856996,0.00006420256,0.0005964968,0.9446808,0.000008239844,0.0036951967,0.050337564],"study_design_scores_gemma":[0.0023655782,0.0021779705,0.00010305803,0.00004705036,0.0000810566,0.0012907827,0.00003244872,0.0004310222,0.93179166,0.00002833929,0.061495528,0.00015552537],"about_ca_topic_score_codex":0.000020156738,"about_ca_topic_score_gemma":0.000013828178,"teacher_disagreement_score":0.057800334,"about_ca_system_score_codex":0.000041622847,"about_ca_system_score_gemma":0.000066363966,"threshold_uncertainty_score":0.6246691},"labels":[],"label_agreement":null},{"id":"W1543492257","doi":"10.1074/jbc.m508001200","title":"Homo- and Hetero-oligomerization of β-Arrestins in Living Cells","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Université de Montréal","funders":"Sidaction; Association pour la Recherche sur le Cancer; Ariad Pharmaceuticals","keywords":"G protein-coupled receptor; Cell biology; Arrestin; Förster resonance energy transfer; Receptor; Signal transduction; Biology; Gene isoform; Immunoprecipitation; HEK 293 cells; Chemistry; Biochemistry; Gene","score_opus":0.011466436292572256,"score_gpt":0.2305654195911979,"score_spread":0.21909898329862562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1543492257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99807686,0.0008671683,0.000789946,0.00003172335,0.000036810023,0.000023018523,0.0000026552839,0.0000014033627,0.00017043334],"genre_scores_gemma":[0.9971324,0.0006553199,0.0018828225,0.0000374275,0.0002469323,6.308777e-7,0.0000032166502,0.000004649163,0.00003659981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993654,0.000025864905,0.0003247249,0.000108660344,0.00006844961,0.00010693924],"domain_scores_gemma":[0.99958473,0.000024533398,0.0002163991,0.0000655084,0.000052216164,0.000056629175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022841759,0.000080250786,0.00016606339,0.000018065512,0.0000145208105,0.000007590318,0.0000978845,0.00015244911,0.0000729476],"category_scores_gemma":[0.00013098586,0.00006057331,0.000062909785,0.000043598513,0.00004532162,0.0000039524807,0.000048487913,0.000101548816,3.0337353e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029405666,0.00005330922,0.0035214943,0.000015388121,0.000009050373,0.000002151471,0.00002089734,0.00015597565,0.99434733,0.0000020425493,0.000014816022,0.0018281162],"study_design_scores_gemma":[0.0001944744,0.00015794788,0.001405131,0.00005167415,0.000003984362,0.000037913935,0.000054289205,0.00005927713,0.9971275,0.00002233228,0.00081459276,0.00007093161],"about_ca_topic_score_codex":0.0000010119523,"about_ca_topic_score_gemma":4.7942603e-7,"teacher_disagreement_score":0.0027800985,"about_ca_system_score_codex":0.000008332859,"about_ca_system_score_gemma":0.000020039424,"threshold_uncertainty_score":0.2470108},"labels":[],"label_agreement":null},{"id":"W1546455379","doi":"10.1111/tra.12073","title":"A Novel Assay for Measurement of Membrane‐Protein Surface Expression using a β‐lactamase Reporter","year":2013,"lang":"en","type":"article","venue":"Traffic","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Protein expression; Membrane; Reporter gene; Membrane protein; Surface (topology); Molecular biology; Computational biology; Biochemistry; Gene expression; Gene","score_opus":0.03529654382583925,"score_gpt":0.25034289404852944,"score_spread":0.2150463502226902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1546455379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9290403,0.0001395206,0.07012387,0.00002201659,0.00007571433,0.0005396162,0.000006255627,0.000009421016,0.00004327439],"genre_scores_gemma":[0.973441,0.0000025508468,0.026259614,0.000020203179,0.00006859939,0.000034478566,0.000014600428,0.000022427688,0.00013653787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908346,0.000028824921,0.00026404762,0.0002502837,0.00019166942,0.00018170344],"domain_scores_gemma":[0.99936134,0.000005985161,0.00014813998,0.00022739479,0.00019744104,0.000059713555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044343993,0.000120075485,0.00014993091,0.000018817176,0.00004752288,0.000016520771,0.00008907651,0.000111427056,0.0000899607],"category_scores_gemma":[0.00006416974,0.000102591584,0.0001105568,0.0000351267,0.00001805986,0.000004778565,0.000025208987,0.000034353267,0.0000014879895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041271796,0.00007770882,0.0000038960225,0.000048337057,0.000022994524,2.9662155e-7,0.00003385822,0.003726166,0.9952708,0.0000054159004,0.00016473673,0.0006045517],"study_design_scores_gemma":[0.0005396609,0.00013437787,0.00000741035,0.00006257499,0.00001404163,0.000005288566,0.00005778043,0.0055890367,0.99285203,0.000007518418,0.0006002895,0.00012997378],"about_ca_topic_score_codex":0.000020758313,"about_ca_topic_score_gemma":0.0000034005404,"teacher_disagreement_score":0.04440068,"about_ca_system_score_codex":0.000014092303,"about_ca_system_score_gemma":0.00006173205,"threshold_uncertainty_score":0.41835636},"labels":[],"label_agreement":null},{"id":"W1551542801","doi":"10.1074/jbc.m210319200","title":"Gαq-coupled Receptor Internalization Specifically Induced by Gαq Signaling","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Internalization; Cell biology; Receptor; Signal transduction; Chemistry; Biology; Biochemistry","score_opus":0.021304423464556986,"score_gpt":0.24493327796435987,"score_spread":0.22362885449980288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1551542801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97756886,0.00087858894,0.020439824,0.000049001876,0.000260817,0.00005987796,0.0000066090493,0.000008433758,0.0007279547],"genre_scores_gemma":[0.9964277,0.00034236643,0.0021839815,0.00016945119,0.00053533766,0.0000027346139,0.000050555893,0.000019376312,0.00026847838],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985172,0.00009585615,0.00062354695,0.00027906112,0.00022103556,0.00026326432],"domain_scores_gemma":[0.99890816,0.000031554493,0.0004628527,0.00016462065,0.00024246878,0.0001903424],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00059680466,0.00021303557,0.00030008465,0.000020954105,0.00006678336,0.00004741759,0.00029849567,0.00041465936,0.0014495886],"category_scores_gemma":[0.00055691524,0.0001599853,0.00023778243,0.000096000935,0.000050565854,0.0000074248715,0.000042674164,0.0002956697,0.0000073834008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013246284,0.000101536185,0.00036594082,0.000010699654,0.000059888785,0.000005006213,0.0000112019325,0.000023816363,0.99790907,0.000036656846,0.0010197501,0.00032399388],"study_design_scores_gemma":[0.00056243467,0.0003746808,0.000017430693,0.000036016416,0.000012311482,0.000065674096,0.00010379005,0.000015585903,0.97660846,0.00020287928,0.021792464,0.0002082668],"about_ca_topic_score_codex":0.0000010214983,"about_ca_topic_score_gemma":8.159497e-8,"teacher_disagreement_score":0.02130058,"about_ca_system_score_codex":0.000037749905,"about_ca_system_score_gemma":0.00007075222,"threshold_uncertainty_score":0.9994632},"labels":[],"label_agreement":null},{"id":"W1552407238","doi":"10.1111/j.1460-9568.2005.03904.x","title":"Coupling of 5‐HT1A autoreceptors to inhibition of mitogen‐activated protein kinase activation via Gβγ subunit signaling","year":2005,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; G protein-coupled receptor; Receptor; 5-HT1A receptor; Protein kinase A; Biology; Chemistry; Signal transduction; Kinase; Biochemistry; 5-HT receptor; Serotonin","score_opus":0.016716026962610833,"score_gpt":0.23707196470092665,"score_spread":0.2203559377383158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1552407238","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9522286,0.000027902885,0.047287785,0.00006696167,0.00021062336,0.00012787558,0.0000032220748,0.0000045800434,0.00004246002],"genre_scores_gemma":[0.9969642,0.000009515512,0.00263986,0.00009050361,0.00021663606,7.379368e-7,0.0000026865907,0.000023218057,0.000052641913],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985985,0.000117179974,0.00056429533,0.00021240061,0.00033395103,0.00017363991],"domain_scores_gemma":[0.99874115,0.000012677544,0.00064453034,0.00015325978,0.00032701416,0.000121343546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008290923,0.00012822077,0.00016981919,0.00015894797,0.0000740753,0.000021827735,0.00025158268,0.000031229065,0.00002126588],"category_scores_gemma":[0.0002818382,0.00011753384,0.000100044614,0.00029750788,0.00006609887,0.000032995526,0.00006968306,0.00013349466,0.0000018481919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012381704,0.000061137405,0.000026174448,0.000012647551,0.000004608741,0.0000044622752,0.00012662486,0.015479802,0.9821176,0.000009874606,0.000024232786,0.0020090311],"study_design_scores_gemma":[0.00032980007,0.0009707166,0.00050412316,0.0001400981,0.000007271925,0.00001437602,0.000048487236,0.0006030876,0.99605066,0.0000041745266,0.0012164946,0.000110693],"about_ca_topic_score_codex":0.0000021466271,"about_ca_topic_score_gemma":2.461612e-7,"teacher_disagreement_score":0.04473561,"about_ca_system_score_codex":0.000017625658,"about_ca_system_score_gemma":0.0000652243,"threshold_uncertainty_score":0.47928908},"labels":[],"label_agreement":null},{"id":"W1555310957","doi":"10.1111/bph.12879","title":"Characterizing pharmacological ligands to study the long‐chain fatty acid receptors <scp>GPR</scp>40/<scp>FFA</scp>1 and <scp>GPR</scp>120/<scp>FFA</scp>4","year":2014,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Strategiske Forskningsråd","keywords":"Chemistry; Receptor; Biochemistry","score_opus":0.02596590394241444,"score_gpt":0.3173296596277992,"score_spread":0.29136375568538475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1555310957","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.50000864,0.49174678,0.00069807284,0.00007293627,0.0044196947,0.0024281158,0.00023474061,0.00007570039,0.0003153266],"genre_scores_gemma":[0.080276445,0.90310174,0.0007869606,0.0022314042,0.009266935,0.0005263372,0.0003997726,0.00050711783,0.0029032754],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.986683,0.0030685228,0.0038128858,0.0023503287,0.0013161863,0.0027690677],"domain_scores_gemma":[0.9908904,0.0019147805,0.0038377957,0.0006617213,0.0010124764,0.0016828453],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow","research_integrity"],"category_scores_codex":[0.0056690793,0.002164074,0.004775514,0.0006884344,0.0012531839,0.0008500326,0.003178772,0.0021695234,0.00020707895],"category_scores_gemma":[0.0030840277,0.0019363456,0.0019181918,0.00096398644,0.000592174,0.00011582306,0.0016943573,0.0041867625,0.00010778961],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004132799,0.0015290158,0.00013831945,0.0014669299,0.0049232026,0.0021557866,0.00077212777,0.000026609741,0.7059929,0.000015240006,0.107477844,0.1754607],"study_design_scores_gemma":[0.0035715213,0.0031797416,0.00018168954,0.0018497157,0.0033244272,0.005832758,0.001308022,0.000015679792,0.19263144,0.000043056174,0.78773946,0.00032252722],"about_ca_topic_score_codex":0.00003407998,"about_ca_topic_score_gemma":0.000019962223,"teacher_disagreement_score":0.6802616,"about_ca_system_score_codex":0.0002832298,"about_ca_system_score_gemma":0.00082112546,"threshold_uncertainty_score":0.9991259},"labels":[],"label_agreement":null},{"id":"W155972311","doi":"10.1096/fasebj.27.1_supplement.883.1","title":"Function of the first intracellular loop for human D1 and D5 dopaminergic receptors","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Adenylyl cyclase; Receptor; Internalization; Dopaminergic; Dopamine; Gs alpha subunit; Mutant; Dopamine receptor; Cell biology; Intracellular; G protein; G protein-coupled receptor; Dopamine receptor D2; Dopamine receptor D1; Chemistry; Biology; Endocrinology; Biochemistry; Gene","score_opus":0.00909417133736476,"score_gpt":0.2066402994090119,"score_spread":0.19754612807164715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W155972311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946015,0.00062222156,0.0038224787,0.00033209796,0.00037236506,0.00016863851,0.000002027136,0.0000019699276,0.000076684715],"genre_scores_gemma":[0.9984193,0.000085796935,0.00011544772,0.000111592904,0.00036992025,0.000009658898,0.0000051354323,0.000011259897,0.0008718903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994909,0.000038761882,0.0001661984,0.00009293327,0.000084449166,0.0001267557],"domain_scores_gemma":[0.9995918,0.000011942294,0.00013166813,0.00014440478,0.00008131732,0.000038849226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028392376,0.000080489765,0.000079494406,0.000014903826,0.00031072163,0.00003869076,0.0001544984,0.000062857296,0.00016696591],"category_scores_gemma":[0.000024079682,0.000042926586,0.0000897534,0.00003387825,0.00006169425,0.0000046522573,0.00004593237,0.00010092538,0.0000017747041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001885807,0.000011561778,0.0003282561,0.0000074146733,0.00003268456,8.061559e-8,0.00003456237,0.00007583625,0.9962125,0.00019712954,0.0015305979,0.0015505078],"study_design_scores_gemma":[0.00034678486,0.00031095644,0.00030644223,0.000017904551,0.0000320221,0.00002594956,0.00020103372,0.000100388344,0.99135184,0.001169149,0.0060678674,0.00006967067],"about_ca_topic_score_codex":0.000012021001,"about_ca_topic_score_gemma":0.0000074618474,"teacher_disagreement_score":0.004860679,"about_ca_system_score_codex":0.000005869295,"about_ca_system_score_gemma":0.000015580212,"threshold_uncertainty_score":0.2389851},"labels":[],"label_agreement":null},{"id":"W1561475358","doi":"10.1007/978-0-387-73657-0_152","title":"Structural changes in the binding pocket of the liganded angiotensin II receptor AT1 during activation.","year":2009,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Angiotensin II receptor type 1; Angiotensin II; Chemistry; Receptor; Internal medicine; Medicine; Biochemistry","score_opus":0.016919387971139052,"score_gpt":0.30530852146614973,"score_spread":0.28838913349501066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1561475358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99098396,0.0073009054,0.000005048844,0.0013110074,0.00016904365,0.00014147891,0.0000017319559,0.0000020521638,0.00008474309],"genre_scores_gemma":[0.9983859,0.0007114723,0.00012951737,0.00055542623,0.00017597439,0.0000067500873,0.000017675702,0.0000034854331,0.000013794366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99941784,0.00006279351,0.00015204058,0.00017420553,0.00005238595,0.00014072272],"domain_scores_gemma":[0.9997709,0.000016853786,0.00007519569,0.00011070119,0.0000116315105,0.00001473975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011889728,0.00009700292,0.00014167136,0.00004352654,0.00008025104,0.0000020721682,0.00012561452,0.00007435253,0.000022637914],"category_scores_gemma":[0.00003418331,0.00005067416,0.000021237478,0.000109422384,0.00012312386,0.000006865091,0.000049577204,0.00007368979,7.027232e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061814026,0.000014458158,0.0013853038,0.0000026358357,0.000003147721,2.8811988e-7,0.00075391395,0.0000033431063,0.9948913,0.0002015844,0.00001652759,0.0026657158],"study_design_scores_gemma":[0.00060714956,0.0006790959,0.0018115289,0.000056027944,0.0000018569438,0.000011640546,0.0023097415,0.0000057764632,0.9931975,0.00021470615,0.0010380121,0.00006695213],"about_ca_topic_score_codex":0.000016726824,"about_ca_topic_score_gemma":0.00002111091,"teacher_disagreement_score":0.0074019157,"about_ca_system_score_codex":0.000009776776,"about_ca_system_score_gemma":0.0000060139714,"threshold_uncertainty_score":0.20664324},"labels":[],"label_agreement":null},{"id":"W1563048317","doi":"10.1046/j.1471-4159.2003.01726.x","title":"Squid visual arrestin: cDNA cloning and calcium‐dependent phosphorylation by rhodopsin kinase (SQRK)","year":2003,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada; Javna Agencija za Raziskovalno Dejavnost RS","keywords":"Rhodopsin; Arrestin; Biology; Complementary DNA; Protein kinase A; Phosphorylation; Biochemistry; Calmodulin; Kinase; Squid; Cell biology; Molecular biology; Signal transduction; G protein-coupled receptor; Enzyme; Gene","score_opus":0.008929751989932498,"score_gpt":0.2512359643093659,"score_spread":0.2423062123194334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1563048317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99255,0.0023701568,0.0043053995,0.00004487223,0.0002529274,0.00004454841,0.0000044712665,0.00000449221,0.0004231064],"genre_scores_gemma":[0.99815834,0.0002296964,0.00085021503,0.00014293886,0.00024568112,0.0000014910064,0.000012480821,0.000024701885,0.00033443057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998886,0.00006185374,0.00037530393,0.00023820515,0.00023143305,0.00020721779],"domain_scores_gemma":[0.9992307,0.000022148626,0.00031079858,0.00012850612,0.00013132446,0.00017651473],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031335876,0.00017298735,0.00018445031,0.000025278556,0.00008741604,0.000052318122,0.000120329845,0.00015278548,0.00006875358],"category_scores_gemma":[0.000292701,0.00016592281,0.00009561995,0.00005341986,0.000036941496,0.000009023786,0.000037804104,0.00023165933,0.0000010464474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007640001,0.000057117053,0.00046380123,0.000021588376,0.000023273766,0.00003298754,0.000018755713,0.000059714243,0.9976128,0.000008480125,0.0011147313,0.0005103589],"study_design_scores_gemma":[0.00062639825,0.0002724583,0.0001366489,0.000032438515,0.000026008145,0.0004560006,0.000097985605,0.00004927948,0.9922578,0.0000405847,0.0058381455,0.00016626596],"about_ca_topic_score_codex":0.0000017921416,"about_ca_topic_score_gemma":2.0679671e-7,"teacher_disagreement_score":0.0056083384,"about_ca_system_score_codex":0.000017574323,"about_ca_system_score_gemma":0.000081329315,"threshold_uncertainty_score":0.6766136},"labels":[],"label_agreement":null},{"id":"W1563683377","doi":"10.1046/j.1471-4159.2001.00005.x","title":"The palmitoylation state of the β<sub>2</sub>‐adrenergic receptor regulates the synergistic action of cyclic AMP‐dependent protein kinase and β‐adrenergic receptor kinase involved in its phosphorylation and desensitization","year":2001,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Homologous desensitization; Beta adrenergic receptor kinase; Phosphorylation; Desensitization (medicine); Agonist; Palmitoylation; Protein kinase A; Receptor; Biology; Chemistry; Kinase; Endocrinology; Biochemistry; G protein-coupled receptor; Enzyme","score_opus":0.0115362257552927,"score_gpt":0.22150967131457738,"score_spread":0.20997344555928468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1563683377","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997773,0.0014738706,0.00021240162,0.00016454331,0.00015877394,0.00019809193,0.000006547649,0.0000027104086,0.000010081024],"genre_scores_gemma":[0.99676543,0.0029135945,0.000060430855,0.000019256859,0.00013197835,0.000007387209,0.000016413665,0.000019143576,0.00006638341],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860334,0.00018493367,0.0005681506,0.00019888363,0.00028726604,0.00015741457],"domain_scores_gemma":[0.9985455,0.00007031613,0.0008214466,0.00022522498,0.00027810474,0.000059383983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004789663,0.00016492137,0.00018633535,0.000040948802,0.00014507186,0.000037339745,0.00016367288,0.00011922202,0.000004039549],"category_scores_gemma":[0.00036329502,0.00010323585,0.00008358192,0.00018646561,0.00011360668,0.000020059197,0.00007173686,0.00020323541,1.7662435e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035556112,0.00003903941,0.00046675027,0.00005071509,0.00002635202,0.0000018408655,0.00006403218,0.0021384212,0.9931195,0.0000113633805,0.00002171948,0.0037047185],"study_design_scores_gemma":[0.0004881977,0.00013105896,0.0035414156,0.00013957251,0.000029215766,0.00003036862,0.00013754235,0.00047151445,0.99458784,0.00020276589,0.00013852358,0.00010197089],"about_ca_topic_score_codex":0.000008982268,"about_ca_topic_score_gemma":0.000031807867,"teacher_disagreement_score":0.0036027476,"about_ca_system_score_codex":0.00002991409,"about_ca_system_score_gemma":0.00007276496,"threshold_uncertainty_score":0.42098355},"labels":[],"label_agreement":null},{"id":"W1573211116","doi":"10.1111/j.1742-4658.2011.08083.x","title":"Structure, signaling mechanism and regulation of the natriuretic peptide receptor guanylate cyclase","year":2011,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Adenylyl cyclase; NPR2; Atrial natriuretic peptide; Chemistry; Receptor; NPR1; Transmembrane domain; Natriuretic peptide; Signal transduction; Cell biology; Aldosterone; Biophysics; Internal medicine; Endocrinology; Biochemistry; Biology; Medicine","score_opus":0.020987258386960035,"score_gpt":0.25756513843596407,"score_spread":0.23657788004900404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1573211116","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006169389,0.9911601,0.001253987,0.000005759137,0.0009305405,0.00033327253,0.000057509293,0.000005038317,0.00008441387],"genre_scores_gemma":[0.0062650586,0.9900479,0.002237382,0.000022629307,0.0007856624,0.000005288162,0.000051408548,0.000069982954,0.00051470497],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982185,0.00029197094,0.0006866157,0.00032350988,0.00022444637,0.00025498867],"domain_scores_gemma":[0.9984012,0.000020286145,0.0009824673,0.00033646869,0.0001421603,0.00011739474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004557559,0.0003524408,0.0006742495,0.00010123862,0.00021143803,0.000057789013,0.00038444076,0.00049540057,0.00042965886],"category_scores_gemma":[0.00009177856,0.00022639018,0.00048930716,0.00011915153,0.00006477545,0.0000069726316,0.00016169736,0.0005115547,0.0000029887615],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009445277,0.000060005506,0.0000073924266,0.004829778,0.0010788905,0.000010209949,0.00022737402,0.00004068801,0.49134865,0.0055208527,0.001656947,0.49512476],"study_design_scores_gemma":[0.0004845888,0.0003260748,0.0000043301475,0.006063883,0.0009414863,0.0013966787,0.000038325194,0.000013247309,0.115203775,0.009443331,0.8654069,0.00067741313],"about_ca_topic_score_codex":0.0000036268352,"about_ca_topic_score_gemma":0.0000018967351,"teacher_disagreement_score":0.8637499,"about_ca_system_score_codex":0.000025450885,"about_ca_system_score_gemma":0.00024396447,"threshold_uncertainty_score":0.9231923},"labels":[],"label_agreement":null},{"id":"W1573282092","doi":"10.1046/j.1432-1033.2002.03071.x","title":"The solution structure and activation of visual arrestin studied by small‐angle X‐ray scattering","year":2002,"lang":"en","type":"article","venue":"European Journal of Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Eye Institute","keywords":"Arrestin; Phosphopeptide; Small-angle X-ray scattering; Rhodopsin; Dimer; Crystallography; Chemistry; Dissociation constant; Biophysics; Mutant; Stereochemistry; Phosphorylation; Scattering; Biochemistry; Biology; Signal transduction; Receptor; G protein-coupled receptor; Physics; Retinal; Optics","score_opus":0.010282379393827656,"score_gpt":0.21160284117882044,"score_spread":0.2013204617849928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1573282092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946541,0.0021379744,0.0027962308,0.00012368296,0.000085925705,0.000029876797,0.000004903111,0.0000021251035,0.00016513838],"genre_scores_gemma":[0.9986831,0.00026803225,0.00056418724,0.000030735453,0.00028084032,2.1731461e-7,0.000007311091,0.000014905794,0.00015065912],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993069,0.00007859168,0.00027319428,0.00011685013,0.000108992,0.0001154332],"domain_scores_gemma":[0.9994156,0.000014094577,0.0003195831,0.00010270931,0.00009406292,0.000053944837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029558945,0.00009916845,0.000098417055,0.000013170313,0.00010520781,0.00002738178,0.00013805072,0.000038143156,0.000019062483],"category_scores_gemma":[0.00009550529,0.00007346396,0.000052923424,0.00003775102,0.00006818987,0.000004015718,0.000060613747,0.00011424698,4.1092227e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003527573,0.000020551377,0.00008532625,0.000015313426,0.00004253958,0.0000018748511,0.000039152223,0.000019840234,0.99021226,5.7183394e-7,0.0014461147,0.008081176],"study_design_scores_gemma":[0.00033770665,0.00020076781,0.00020545426,0.000046823243,0.000012242681,0.000030071136,0.00011102883,0.0000646162,0.99718523,0.0000047042768,0.0017220436,0.00007933795],"about_ca_topic_score_codex":6.11182e-7,"about_ca_topic_score_gemma":1.3393826e-7,"teacher_disagreement_score":0.008001839,"about_ca_system_score_codex":0.000008679496,"about_ca_system_score_gemma":0.000009749032,"threshold_uncertainty_score":0.29957733},"labels":[],"label_agreement":null},{"id":"W1577210083","doi":"10.1111/j.1742-4658.2011.08459.x","title":"Ser/ Thr residues at α3/β5 loop of Gαs are important in morphine‐induced adenylyl cyclase sensitization but not mitogen‐activated protein kinase phosphorylation","year":2011,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Tehran University of Medical Sciences and Health Services; University of Tehran","keywords":"Adenylyl cyclase; Protein kinase A; Phosphorylation; Chemistry; Sensitization; Dephosphorylation; Kinase; MAPK/ERK pathway; Molecular biology; Receptor; Opioid; Gs alpha subunit; Internal medicine; Pharmacology; Endocrinology; Biology; Biochemistry; Medicine; Immunology","score_opus":0.023990800183975123,"score_gpt":0.23071383751100433,"score_spread":0.2067230373270292,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1577210083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99843156,0.000311485,0.00061532704,0.00006415307,0.00021666555,0.00025263653,0.000019528637,0.0000078896255,0.00008073101],"genre_scores_gemma":[0.99826044,0.00013620623,0.0007928164,0.00004504274,0.0002130622,0.000008124018,0.00006324554,0.000033590724,0.00044745227],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985702,0.0001188282,0.00054988224,0.0002713145,0.0002337459,0.00025605407],"domain_scores_gemma":[0.9988632,0.000007396358,0.00056770846,0.00021139656,0.00023157419,0.000118723496],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036153945,0.00019539885,0.00022969165,0.000107083,0.00011667898,0.000024716663,0.0001225122,0.00023522889,0.00026880912],"category_scores_gemma":[0.00013830242,0.00017720052,0.00011029177,0.00011097034,0.000026058964,0.000019041148,0.0000617491,0.00020822663,0.0000056961985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007739189,0.00007092506,0.005681631,0.000020057982,0.000040810668,0.00006750037,0.00022870123,0.00007595234,0.9926996,0.000017509896,0.00008122856,0.00024213102],"study_design_scores_gemma":[0.000845768,0.00026125563,0.010089051,0.00012542149,0.00001718928,0.00009514337,0.00016978888,0.00018907314,0.9877466,0.00020931421,0.00004679751,0.00020462746],"about_ca_topic_score_codex":0.00012664076,"about_ca_topic_score_gemma":0.00015008768,"teacher_disagreement_score":0.004953063,"about_ca_system_score_codex":0.000056943805,"about_ca_system_score_gemma":0.0000939892,"threshold_uncertainty_score":0.7226027},"labels":[],"label_agreement":null},{"id":"W1578155053","doi":"10.1002/9781444300918.ch28","title":"Adrenergic Agonists and Antagonists","year":2008,"lang":"en","type":"other","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":328,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; St. Paul's Hospital","funders":"","keywords":"Adrenergic; Adrenergic antagonist; Adrenergic receptor; Pharmacology; Medicine; Internal medicine; Receptor","score_opus":0.006088729870700454,"score_gpt":0.21512768320888656,"score_spread":0.20903895333818612,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1578155053","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0023667908,0.010734783,0.0014664822,0.000028456778,0.00042249777,0.00017704986,0.000037085603,0.00007342617,0.9846934],"genre_scores_gemma":[0.007728882,0.009254199,0.0025975578,0.0002116803,0.000717163,0.000009894311,0.0002752603,0.00030798226,0.9788974],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.999247,0.000017937671,0.000104027844,0.00037095416,0.00008582825,0.00017423114],"domain_scores_gemma":[0.99959856,0.0000015652915,0.00006590608,0.000240356,0.000012046049,0.000081538994],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000031676816,0.00021100264,0.00018138805,0.000049026945,0.000044413395,0.000019344785,0.00010175914,0.00037061475,0.0017077953],"category_scores_gemma":[0.0000054142024,0.0001842276,0.00006250997,0.000025463949,0.000058721973,4.002312e-7,0.00007848362,0.00006162341,0.000030626332],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009209204,0.000018048439,0.000037756643,0.000027212736,0.000074919706,0.000014172745,0.0000060930715,7.100695e-7,0.16005166,0.00038415674,0.8373353,0.0020407573],"study_design_scores_gemma":[0.00019032536,0.000075498036,0.000006790488,0.000020414227,0.0000090836775,0.00005555352,0.000005781918,0.0000038065264,0.07372544,0.000015231919,0.925643,0.00024903382],"about_ca_topic_score_codex":0.00008093813,"about_ca_topic_score_gemma":0.000060695864,"teacher_disagreement_score":0.08830773,"about_ca_system_score_codex":0.0000032265891,"about_ca_system_score_gemma":0.000038925198,"threshold_uncertainty_score":0.99920475},"labels":[],"label_agreement":null},{"id":"W1581533309","doi":"10.1038/79767","title":"Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCR1","year":2000,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":229,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"Cell biology; Exocytosis; Chemotaxis; Chemokine; Granule (geology); Chemistry; Tyrosine kinase; Signal transduction; Biology; Receptor; Secretion; Biochemistry","score_opus":0.003229645076029552,"score_gpt":0.21867966568610156,"score_spread":0.215450020610072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1581533309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917958,0.006208055,0.0010638231,0.0002256257,0.00009797252,0.00010186087,0.000013186926,0.000010084695,0.00048358942],"genre_scores_gemma":[0.9971553,0.0006557463,0.0010130744,0.00017634114,0.00006642736,0.0000058675178,0.00028485068,0.000012836156,0.0006295563],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993943,0.000051505263,0.00014966086,0.00021691198,0.0000623915,0.00012523563],"domain_scores_gemma":[0.9996615,0.000011889191,0.00007330982,0.00018027937,0.00005556262,0.000017469465],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006835146,0.00010082065,0.00011815843,0.00002064477,0.000054963486,0.000006341732,0.00007244083,0.00043987646,0.00026621553],"category_scores_gemma":[0.000054810946,0.000095055875,0.00003291666,0.00006938576,0.000068964095,0.0000073738893,0.00002115535,0.00017053954,0.000002723118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021905251,0.000032757805,0.000053273867,0.0000070110877,0.000021869711,3.0145293e-7,0.000028607536,0.000017123188,0.9831651,0.00049476227,0.0014221256,0.014538029],"study_design_scores_gemma":[0.0005144288,0.00021201001,0.0014653811,0.000015115889,0.000008844031,0.000007799852,0.00001573662,0.00003063363,0.958671,0.0007452574,0.03821846,0.00009536564],"about_ca_topic_score_codex":0.00003607559,"about_ca_topic_score_gemma":0.0000023611778,"teacher_disagreement_score":0.036796335,"about_ca_system_score_codex":0.000006853902,"about_ca_system_score_gemma":0.000016860957,"threshold_uncertainty_score":0.3876266},"labels":[],"label_agreement":null},{"id":"W1583217239","doi":"10.1016/b978-0-12-407865-9.00007-8","title":"Quantification of Receptor Tyrosine Kinase Activation and Transactivation by G-Protein-Coupled Receptors Using Spatial Intensity Distribution Analysis (SpIDA)","year":2013,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université Laval","funders":"","keywords":"Biophysics; Receptor; Chemistry; Förster resonance energy transfer; Receptor tyrosine kinase; Transactivation; Confocal microscopy; Biological system; Fluorescence; Biochemistry; Biology; Cell biology; Physics; Optics","score_opus":0.03091090795334875,"score_gpt":0.35056395692099834,"score_spread":0.31965304896764957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1583217239","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.49740183,0.0001421111,0.501603,0.00010540588,0.00028540526,0.00042436458,0.000016857039,0.0000123544305,0.000008663086],"genre_scores_gemma":[0.5949355,0.000063480475,0.40428677,0.00008469897,0.00005950049,0.000107914275,0.00039620436,0.000031472096,0.000034474215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9926308,0.0042882217,0.0011943813,0.0011218725,0.0001934661,0.00057125086],"domain_scores_gemma":[0.9975854,0.0006750205,0.0007019756,0.0005984895,0.00032218554,0.00011692256],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0045644366,0.00045396242,0.0010650071,0.00063220196,0.00012917747,0.000025967514,0.0002856789,0.0013527622,0.00032302472],"category_scores_gemma":[0.0024022455,0.00047100408,0.00020345664,0.0010870175,0.0003864205,0.000041446565,0.00009736003,0.0006812472,0.0000021727478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005293871,0.00028118727,0.0028842064,0.000033895798,0.00016184092,9.675583e-7,0.00013462857,0.0019737124,0.96348906,0.00023815384,0.000041231597,0.030231744],"study_design_scores_gemma":[0.001004171,0.00071645726,0.021051712,0.000043799893,0.00010531786,0.0000067305623,0.00019257642,0.012879163,0.96189976,0.0014053726,0.00027245283,0.00042248363],"about_ca_topic_score_codex":0.0021404352,"about_ca_topic_score_gemma":0.00018445539,"teacher_disagreement_score":0.09753364,"about_ca_system_score_codex":0.00017888908,"about_ca_system_score_gemma":0.00007002822,"threshold_uncertainty_score":0.9999437},"labels":[],"label_agreement":null},{"id":"W1587053645","doi":"10.1016/s0079-6123(08)00920-5","title":"PTEN-5-HT2C coupling: a new target for treating drug addiction","year":2008,"lang":"en","type":"review","venue":"Progress in brain research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mental Health Research Canada; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Conditioned place preference; Ventral tegmental area; Neuroscience; Dopaminergic; Dopamine; Tensin; Chemistry; Pharmacology; PTEN; Agonist; Psychology; Receptor; Medicine; PI3K/AKT/mTOR pathway; Biochemistry; Signal transduction","score_opus":0.09962640065644672,"score_gpt":0.43482095797138226,"score_spread":0.3351945573149355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1587053645","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010340565,0.9966315,0.00073979114,0.00008219256,0.00019168365,0.0019993922,0.000049435217,0.000023388498,0.00017918836],"genre_scores_gemma":[0.000054321154,0.9872725,0.0057456503,0.000012009751,0.0013072456,0.0013072224,0.0010344626,0.00012990375,0.0031366858],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99680364,0.00028491972,0.0006233674,0.00092260994,0.00050205976,0.00086339813],"domain_scores_gemma":[0.9985678,0.00032773972,0.00019732119,0.0004842918,0.00022432023,0.00019849034],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001761312,0.00038742178,0.00083840796,0.00037638488,0.00028223687,0.0001027169,0.0005765971,0.000584019,0.00008695064],"category_scores_gemma":[0.00062719727,0.00034096898,0.0004232525,0.0004655268,0.00014939204,0.000005876546,0.00026354345,0.0006714264,0.0000145805325],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004744369,0.0000770971,0.000022610087,0.0019355315,0.00010268804,0.000012917172,0.00005696142,0.000009711925,0.00009391356,0.000084331805,0.021088628,0.97646815],"study_design_scores_gemma":[0.00048138393,0.00027323366,8.685925e-7,0.0030347873,0.000020122072,0.000024905537,0.000028879887,0.0004358439,0.00096913206,0.00011669131,0.9942753,0.00033886256],"about_ca_topic_score_codex":0.00003707737,"about_ca_topic_score_gemma":0.000015577878,"teacher_disagreement_score":0.9761293,"about_ca_system_score_codex":0.000111375026,"about_ca_system_score_gemma":0.00088479085,"threshold_uncertainty_score":0.9999042},"labels":[],"label_agreement":null},{"id":"W1593172464","doi":"10.1111/j.1742-4658.2005.04731.x","title":"Methods to monitor the quaternary structure of G protein‐coupled receptors","year":2005,"lang":"en","type":"review","venue":"FEBS Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":207,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Protein quaternary structure; Receptor; G protein-coupled receptor; Computational biology; Förster resonance energy transfer; Immunoprecipitation; Function (biology); Protein structure; Biology; Computer science; Chemistry; Cell biology; Physics; Biochemistry; Gene","score_opus":0.03006379562238031,"score_gpt":0.36665866594780355,"score_spread":0.33659487032542323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1593172464","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00084915606,0.98914975,0.008107411,0.00004093374,0.0011812325,0.0006110784,0.000026224041,0.0000048698544,0.000029316763],"genre_scores_gemma":[0.00015050643,0.94948673,0.04517033,0.000045220826,0.0041343067,0.000023308556,0.00003729211,0.000075561235,0.0008767213],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978148,0.0005723961,0.00072970655,0.00031139542,0.00026198925,0.0003097266],"domain_scores_gemma":[0.9985791,0.000027653614,0.00065980526,0.00041838727,0.00014550232,0.00016956538],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007021969,0.0003785528,0.0008321392,0.00010382932,0.00015572277,0.00007318166,0.0007376147,0.00043706712,0.0005255887],"category_scores_gemma":[0.00013136653,0.00021895689,0.0006248027,0.00015330843,0.00003565585,0.0000038861517,0.00016313756,0.0006036184,0.00000974302],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002112639,0.00001388026,4.1191066e-7,0.00037210947,0.00024042673,0.0000025985785,0.00003569402,0.000020633393,0.077231355,0.000009474265,0.0008431421,0.92120916],"study_design_scores_gemma":[0.000104930376,0.00023740347,2.5643783e-7,0.0015338146,0.00018642939,0.00020961797,0.000029416624,0.000005610091,0.029130032,0.000057293695,0.9682454,0.0002597952],"about_ca_topic_score_codex":0.0000060481675,"about_ca_topic_score_gemma":0.000001957374,"teacher_disagreement_score":0.9674023,"about_ca_system_score_codex":0.000040895276,"about_ca_system_score_gemma":0.00019765332,"threshold_uncertainty_score":0.8928803},"labels":[],"label_agreement":null},{"id":"W1595449036","doi":"10.1038/35067575","title":"Oligomerization of G-protein-coupled transmitter receptors","year":2001,"lang":"en","type":"review","venue":"Nature reviews. Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":658,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Receptor; Biogenesis; G protein-coupled receptor; Signal transduction; Biology; Function (biology); Cell biology; G protein; Neuroscience; Computational biology; Biochemistry; Gene","score_opus":0.02904340345798836,"score_gpt":0.32032435560925815,"score_spread":0.2912809521512698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1595449036","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000047183326,0.99411863,0.0033412115,0.000011346821,0.0009954362,0.0012782895,0.000016783199,0.000012810061,0.00017830745],"genre_scores_gemma":[0.000059860315,0.99776363,0.0006252153,0.00023388826,0.00029299935,0.00010699014,0.00011895606,0.000060307564,0.00073814945],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99720794,0.0002947819,0.0008901377,0.0009036138,0.0003440809,0.00035942724],"domain_scores_gemma":[0.9983808,0.00001381873,0.0007335111,0.00066808757,0.00008662064,0.000117163094],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055843306,0.0005025429,0.0014190936,0.00014272076,0.00008937386,0.000035940717,0.00080335175,0.0008574653,0.000096098614],"category_scores_gemma":[0.0003239949,0.0003709845,0.00077235204,0.0009532052,0.00011863788,0.000009270898,0.00009566452,0.0006147491,0.000014090362],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000036803874,0.000034477867,5.4898874e-7,0.004406643,0.000009922196,0.0000025485597,0.000004416628,0.0000010500768,0.12582389,0.00007808659,0.00015009241,0.86948466],"study_design_scores_gemma":[0.00007073184,0.0001364831,3.982189e-7,0.003998435,0.00014005521,0.00003133724,7.522249e-7,0.0000055992277,0.0048113507,0.000010315623,0.99044925,0.00034530458],"about_ca_topic_score_codex":0.0000022136433,"about_ca_topic_score_gemma":9.657982e-7,"teacher_disagreement_score":0.99029917,"about_ca_system_score_codex":0.000017766808,"about_ca_system_score_gemma":0.00020131371,"threshold_uncertainty_score":0.99987423},"labels":[],"label_agreement":null},{"id":"W1595808099","doi":"10.1111/bph.12040","title":"<scp>GPCR</scp> heterodimers: asymmetries in ligand binding and signalling output offer new targets for drug discovery","year":2012,"lang":"en","type":"letter","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Drug discovery; G protein-coupled receptor; Computational biology; Signalling; Drug; Ligand (biochemistry); Chemistry; Neuroscience; Pharmacology; Receptor; Computer science; Data science; Biology; Cell biology; Biochemistry","score_opus":0.01605394402655183,"score_gpt":0.25790673405951003,"score_spread":0.2418527900329582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1595808099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89916474,0.07623015,0.008157872,0.010698414,0.004876174,0.0006296237,0.00018058662,0.000008932594,0.000053487136],"genre_scores_gemma":[0.7099102,0.030615106,0.00802701,0.17216496,0.06020226,0.00008083255,0.0009468704,0.00050228374,0.017550489],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976341,0.00021053615,0.0007792252,0.000419611,0.00023583641,0.00072068087],"domain_scores_gemma":[0.99865013,0.000255174,0.00070432236,0.00006874419,0.00016024488,0.00016138944],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00087013433,0.00035829545,0.00073817035,0.00030881987,0.000120081364,0.00019610139,0.00034766478,0.00072912656,0.00003160258],"category_scores_gemma":[0.00019182889,0.00040154898,0.00031664866,0.00009556594,0.00008799255,0.000052057294,0.00013602473,0.0011994531,0.0000017656903],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039774863,0.000033542896,0.00009426473,0.00010934537,0.00027042968,0.00025485412,0.00007192633,0.00003046805,0.41967204,8.0716285e-7,0.5772632,0.0021593678],"study_design_scores_gemma":[0.0019026663,0.00028928046,0.00002751013,0.00022876938,0.00022005838,0.00095846446,0.00007028176,0.000011859584,0.49011415,0.000078542675,0.5059031,0.00019525563],"about_ca_topic_score_codex":0.00004529181,"about_ca_topic_score_gemma":0.0000139460435,"teacher_disagreement_score":0.18925457,"about_ca_system_score_codex":0.00004916566,"about_ca_system_score_gemma":0.0002261085,"threshold_uncertainty_score":0.99984366},"labels":[],"label_agreement":null},{"id":"W1596233727","doi":"10.1038/sj.jcbfm.9591524.0611","title":"The D2-agonist radiotracer [<sup>11</sup>C]-(+)-PHNO shows a marked increase in sensitivity to amphetamine challenges when compared to [<sup>11</sup>C]raclopride in the cat brain","year":2005,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Raclopride; Agonist; Amphetamine; Medicine; Neuroscience; Pharmacology; Anesthesia; Dopamine receptor D2; Psychology; Internal medicine; Dopamine; Receptor","score_opus":0.01107702111962881,"score_gpt":0.2370512429264049,"score_spread":0.2259742218067761,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1596233727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9750993,0.005662038,0.00065344595,0.01739601,0.00021842253,0.00073131424,0.000061662,0.000012726222,0.00016508272],"genre_scores_gemma":[0.9824485,0.0007591151,0.009743163,0.004047591,0.0024996258,0.000043804135,0.000029242312,0.000077642915,0.00035132183],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99474305,0.0014957696,0.0013072722,0.0006505353,0.00084281655,0.0009605758],"domain_scores_gemma":[0.997622,0.0003648007,0.0004039552,0.00081935176,0.00030144944,0.0004884165],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005057902,0.0006049911,0.0010203241,0.00030462362,0.00028624502,0.00026532376,0.0009546469,0.0003273829,0.000114802846],"category_scores_gemma":[0.00091212237,0.00041090054,0.00047869046,0.00036926728,0.0001070967,0.000064936976,0.00027732275,0.0006132626,0.000015552358],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0030931644,0.00216406,0.0031580892,0.000107949476,0.0009512163,0.0006781474,0.018245043,0.08484742,0.7769954,0.0009467893,0.020563148,0.088249534],"study_design_scores_gemma":[0.014867986,0.0010684626,0.02116784,0.0004428153,0.00078088476,0.0027463883,0.009014739,0.03082805,0.2066543,0.00068375043,0.7093283,0.0024164987],"about_ca_topic_score_codex":0.00039232126,"about_ca_topic_score_gemma":0.0053763054,"teacher_disagreement_score":0.68876517,"about_ca_system_score_codex":0.0000772019,"about_ca_system_score_gemma":0.00026045283,"threshold_uncertainty_score":0.9998343},"labels":[],"label_agreement":null},{"id":"W1597215001","doi":"10.3317/jraas.2001.015","title":"Enhanced regional AT2-receptor and PKCε expression during cardioprotection induced by AT1-receptor blockade after reperfused myocardial infarction","year":2001,"lang":"en","type":"article","venue":"Journal of the Renin-Angiotensin-Aldosterone System","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chelerythrine; Internal medicine; Endocrinology; Cardioprotection; Angiotensin II receptor type 1; Protein kinase C; Candesartan; Angiotensin II; Chemistry; Rottlerin; Receptor; Medicine; Pharmacology; Ischemia; Kinase; Biochemistry","score_opus":0.007150439724724039,"score_gpt":0.20451791106944942,"score_spread":0.19736747134472538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1597215001","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941084,0.0012974346,0.0016251787,0.0006424409,0.0018663453,0.00040412616,0.000011742707,0.000022456657,0.000021898575],"genre_scores_gemma":[0.99645376,0.00017104864,0.00063478725,0.000071621915,0.0021282446,0.000019745605,0.000012530838,0.00006293392,0.00044533404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973818,0.00041458552,0.0007800129,0.0004572684,0.0005788717,0.0003874298],"domain_scores_gemma":[0.99817663,0.000015639122,0.00080209365,0.00047057006,0.00033907618,0.00019595739],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005803132,0.00036182845,0.0005330126,0.00012514848,0.00030519295,0.000093449926,0.00024801612,0.0004255845,0.000027517757],"category_scores_gemma":[0.00006991369,0.0002653233,0.00047436045,0.0001801838,0.00006105889,0.000040157036,0.0001771523,0.0003955078,0.0000075971566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001302903,0.000026874304,0.00036586163,0.000022022845,0.00022352565,0.0000048137613,0.00018376036,0.00007589161,0.99583995,6.924466e-7,0.0011655326,0.0007881518],"study_design_scores_gemma":[0.0016375493,0.00045039697,0.0025163589,0.0005158712,0.0001022375,0.0010063845,0.00018839254,0.000022090191,0.9872507,0.0000024372246,0.0059897257,0.00031789206],"about_ca_topic_score_codex":0.000041175746,"about_ca_topic_score_gemma":0.0000044700582,"teacher_disagreement_score":0.008589306,"about_ca_system_score_codex":0.00016479651,"about_ca_system_score_gemma":0.000070509726,"threshold_uncertainty_score":0.9999799},"labels":[],"label_agreement":null},{"id":"W1601820621","doi":"10.1046/j.1471-4159.2002.01001.x","title":"Homologous regulation of the heptahelical D1A receptor responsiveness: specific cytoplasmic tail regions mediate dopamine‐induced phosphorylation, desensitization and endocytosis","year":2002,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Homologous desensitization; Phosphorylation; Cell biology; Desensitization (medicine); G protein-coupled receptor; Biology; Receptor; Endocytosis; Adenylyl cyclase; HEK 293 cells; Molecular biology; Signal transduction; Biochemistry","score_opus":0.016095996752640816,"score_gpt":0.2110065551127535,"score_spread":0.1949105583601127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1601820621","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979444,0.0007323712,0.0005809254,0.0003316357,0.00023468673,0.00007949016,0.0000051071356,0.000003978209,0.00008740188],"genre_scores_gemma":[0.99783784,0.0011966162,0.00035327653,0.000060807983,0.000304277,0.0000020595562,0.000008635517,0.000019194906,0.00021727021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885446,0.00011348281,0.00045215266,0.00019721263,0.00024631465,0.00013637432],"domain_scores_gemma":[0.9987475,0.000056135006,0.0005293903,0.0002456148,0.00034164978,0.000079687976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016496776,0.00013812416,0.00019307327,0.00004516012,0.00010778526,0.000020625155,0.0001694999,0.00016333234,0.00006614793],"category_scores_gemma":[0.00030570352,0.00011104873,0.00011457118,0.0001509521,0.00007056601,0.000011360892,0.000057856967,0.00018028385,0.0000010930605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119578544,0.000045789773,0.00021536279,0.000017491713,0.000022401398,0.00000428195,0.00007899472,0.00017575093,0.9976721,0.000013648808,0.0009473381,0.0006872524],"study_design_scores_gemma":[0.00056116265,0.00020280892,0.0023984362,0.000050888764,0.000027088317,0.00038072097,0.00010478342,0.00015430682,0.99326485,0.000056772667,0.0026911478,0.00010701789],"about_ca_topic_score_codex":0.0000010845588,"about_ca_topic_score_gemma":6.7523166e-7,"teacher_disagreement_score":0.0044072433,"about_ca_system_score_codex":0.000021762682,"about_ca_system_score_gemma":0.00003915279,"threshold_uncertainty_score":0.45284358},"labels":[],"label_agreement":null},{"id":"W1603691198","doi":"10.1139/y06-087","title":"Differential effects of losartan and candesartan on vasoconstrictor responses in the ratThis paper is one of a selection of papers published in this Special Issue, entitled The Cellular and Molecular Basis of Cardiovascular Dysfunction, Dhalla 70th Birthday Tribute.","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of Environmental Health Sciences; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Losartan; Candesartan; Angiotensin II; Internal medicine; Thromboxane A2; Endocrinology; Thromboxane; Angiotensin II receptor type 1; Angiotensin receptor; Norepinephrine; Medicine; Vasoconstriction; Pharmacology; Chemistry; Blood pressure; Receptor; Platelet","score_opus":0.004789062088956455,"score_gpt":0.21127740470823725,"score_spread":0.20648834261928078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1603691198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99730617,0.0019243064,0.000046545745,0.00017560791,0.00027628615,0.000191975,0.000015436954,3.172186e-7,0.00006334802],"genre_scores_gemma":[0.9988755,0.00068781135,0.000019732632,0.00016435662,0.00022497025,0.0000029810108,0.0000044741105,0.00000647836,0.00001368077],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872774,0.00046333412,0.00038714544,0.00015373333,0.00009486144,0.00017316651],"domain_scores_gemma":[0.99928445,0.00017438424,0.0002471853,0.00009265496,0.00012298362,0.00007837088],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006441366,0.00011355907,0.00039970267,0.00021563229,0.00004583715,0.0000042320053,0.00010627298,0.00016734231,0.00262649],"category_scores_gemma":[0.00009017263,0.00008083573,0.00011508315,0.00016582948,0.0002683745,0.0000085665815,0.000014739387,0.00018817258,5.6812446e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007480803,0.00005155641,0.0022173603,0.00009144303,0.00040816935,0.000011235778,0.00042802445,0.000022289756,0.99500024,0.000048551192,0.00040587626,0.00056717364],"study_design_scores_gemma":[0.0015237825,0.0011351203,0.006563933,0.00002904003,0.00017654322,0.000011657932,0.0001432078,0.0000070840365,0.98759484,0.0000952856,0.0026527215,0.00006680581],"about_ca_topic_score_codex":0.00076480303,"about_ca_topic_score_gemma":0.0008577351,"teacher_disagreement_score":0.007405421,"about_ca_system_score_codex":0.00001547811,"about_ca_system_score_gemma":0.00018699237,"threshold_uncertainty_score":0.99828523},"labels":[],"label_agreement":null},{"id":"W1611952776","doi":"10.1002/047001153x.g303315","title":"Energy transfer–based approaches to study <scp>G</scp> protein–coupled receptor dimerization and activation","year":2005,"lang":"en","type":"other","venue":"Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"G protein-coupled receptor; Receptor; Energy transfer; G protein; Computational biology; Energy (signal processing); Chemistry; Computer science; Biology; Physics; Biochemistry; Chemical physics","score_opus":0.014474429803095514,"score_gpt":0.19817231153904233,"score_spread":0.1836978817359468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1611952776","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6977975,0.001969451,0.2829784,0.00008074645,0.0003368429,0.0056582885,0.00031110234,0.00006495678,0.010802742],"genre_scores_gemma":[0.13409549,0.020440117,0.77371985,0.0006480353,0.003256865,0.0011646153,0.0028437313,0.0016597479,0.062171567],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980158,0.00006404397,0.0007819596,0.00052677974,0.00025061658,0.00036079134],"domain_scores_gemma":[0.99882,0.00001772717,0.0004130791,0.00045925626,0.00007556166,0.00021435038],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030345266,0.0005399518,0.00053376675,0.00028009288,0.000102934595,0.000074690804,0.00026990473,0.0005611466,0.00004305487],"category_scores_gemma":[0.00006678578,0.00054083864,0.00009337134,0.00011619546,0.000096870564,0.000010397265,0.00016954684,0.00015454968,0.0000034588386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026637356,0.0011973245,0.0008365962,0.0016717893,0.0011618965,0.0000013344156,0.0061899778,0.0013926842,0.82347494,0.00039801752,0.007183216,0.15622588],"study_design_scores_gemma":[0.0027145657,0.0028467877,0.00012205695,0.00024609145,0.00021553329,0.0000034924863,0.0019006163,0.012786881,0.61836296,0.00007170997,0.3597541,0.00097523275],"about_ca_topic_score_codex":0.00005531468,"about_ca_topic_score_gemma":0.000051497445,"teacher_disagreement_score":0.563702,"about_ca_system_score_codex":0.000028325665,"about_ca_system_score_gemma":0.00017085214,"threshold_uncertainty_score":0.9997043},"labels":[],"label_agreement":null},{"id":"W163374637","doi":"10.1007/978-0-387-26575-9_202","title":"Structure Determination of the Human Angiotensin II Receptor Type 1 by the Methionine Proximity Assay","year":2010,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Methionine; Receptor; Angiotensin II; Chemistry; Biochemistry; Amino acid","score_opus":0.01031658802285768,"score_gpt":0.23508976107400187,"score_spread":0.2247731730511442,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W163374637","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5114035,0.00755966,0.020718114,0.007545239,0.013330027,0.008578091,0.001986874,0.00019600622,0.42868248],"genre_scores_gemma":[0.26722392,0.00009129125,0.0054855705,0.00053257257,0.0007989644,0.0000062815775,0.000770912,0.000105356085,0.7249851],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904144,0.000051395447,0.00025008898,0.00030384894,0.00022246374,0.00013079194],"domain_scores_gemma":[0.9988369,0.000013337253,0.0002909986,0.0005604743,0.0002657018,0.000032631375],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028664453,0.00023849793,0.00020343112,0.000020491781,0.0002611841,0.0000177401,0.0003673927,0.000775053,0.0014114119],"category_scores_gemma":[0.000061879065,0.0001277574,0.00018235875,0.00002279622,0.00012962802,0.00000242793,0.0002148741,0.00042756269,0.0000023098473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000081236385,0.000006341814,0.000002564669,0.000007300183,0.000037389316,7.7602515e-8,0.000020470135,4.1896462e-7,0.9873852,0.004522834,0.0052829464,0.0027263085],"study_design_scores_gemma":[0.0000833126,0.00011636929,0.0000036903605,0.000018405253,0.000041954838,0.0000041858266,0.0000037844927,0.000006251991,0.77991396,0.0027056667,0.21695791,0.00014452121],"about_ca_topic_score_codex":0.000014410949,"about_ca_topic_score_gemma":0.00006691971,"teacher_disagreement_score":0.29630265,"about_ca_system_score_codex":0.000010794204,"about_ca_system_score_gemma":0.0000575994,"threshold_uncertainty_score":0.9995014},"labels":[],"label_agreement":null},{"id":"W1635444023","doi":"10.1016/j.ymeth.2015.09.010","title":"Practical guide for calculating and representing biased signaling by GPCR ligands: A stepwise approach","year":2015,"lang":"en","type":"review","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Footprint; Effector; Computer science; Computational biology; Interpretation (philosophy); Signal transduction; Biology; Cell biology","score_opus":0.1827341570600165,"score_gpt":0.49875371966234694,"score_spread":0.31601956260233044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1635444023","genre_codex":"review","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00004000205,0.6394706,0.35952902,0.0000054550214,0.000092399016,0.00063186686,0.00001948854,0.000009888467,0.00020131224],"genre_scores_gemma":[0.000004529655,0.42101464,0.57775193,0.0000218313,0.0002857479,0.00020617731,0.00029989198,0.000073291485,0.00034195924],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970491,0.0007054338,0.0007936681,0.0008771438,0.00015900876,0.0004156527],"domain_scores_gemma":[0.99855465,0.00038817842,0.00041014797,0.00038553195,0.00010529828,0.0001562116],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005709383,0.00039188575,0.001180045,0.000095072566,0.0000881161,0.00009224248,0.00017371326,0.00059665734,0.000006148821],"category_scores_gemma":[0.0021904474,0.00033583512,0.00032172535,0.00015988824,0.000036973597,0.00000630016,0.00015293648,0.0002873767,4.930342e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022532518,0.00006165102,0.000003126461,0.0041849907,0.00015915491,0.000004572887,0.00005467957,0.000017712993,0.058352128,0.000051008847,0.002197009,0.93489146],"study_design_scores_gemma":[0.0004131948,0.00009534461,2.682144e-8,0.0010827278,0.000292708,0.00005019994,0.000113584174,0.0012525588,0.014718897,0.00006346247,0.98147047,0.00044684828],"about_ca_topic_score_codex":0.000018340506,"about_ca_topic_score_gemma":6.990264e-7,"teacher_disagreement_score":0.97927344,"about_ca_system_score_codex":0.000034646586,"about_ca_system_score_gemma":0.00022861442,"threshold_uncertainty_score":0.99990934},"labels":[],"label_agreement":null},{"id":"W164138431","doi":"10.1096/fasebj.27.1_supplement.928.11","title":"Autonomic dysregulation in a genetically modified mouse with reduced expression of the vesicular acetylcholine transporter (VAChT KDHOM)","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Baroreflex; Vesicular acetylcholine transporter; Heart rate; Phenylephrine; Medicine; Internal medicine; Endocrinology; Anesthesia; Blood pressure; Baroreceptor; Acetylcholine; Choline acetyltransferase","score_opus":0.00809305239456106,"score_gpt":0.2022596064103939,"score_spread":0.19416655401583283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W164138431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922477,0.00013453708,0.00703873,0.00023958158,0.00005892946,0.00022014674,0.000002613061,0.0000026678208,0.00005507262],"genre_scores_gemma":[0.9985353,0.0000370008,0.0010277882,0.0000832458,0.00010843078,0.000010798792,0.000007218616,0.000016609214,0.00017365305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991701,0.0001088195,0.00026870015,0.00013468319,0.00015157668,0.00016609281],"domain_scores_gemma":[0.9994654,0.0000062482677,0.00015077676,0.00026446735,0.00006249344,0.000050629675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025160206,0.0001103365,0.000118921474,0.00002672103,0.00008916727,0.000028342298,0.00025036887,0.00008459624,0.000093290444],"category_scores_gemma":[0.0000090237745,0.000055338904,0.00008581419,0.00005544398,0.00005695707,0.000007909554,0.000028043376,0.00016753661,0.0000015070834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084442545,0.000031442487,0.0002456382,0.0000028664742,0.000016728321,6.0476725e-7,0.00014302206,0.0108557595,0.9879665,0.000019279694,0.00004018015,0.0005935469],"study_design_scores_gemma":[0.0006934233,0.000097569864,0.004951569,0.000039480827,0.000016539461,0.000030390884,0.00007895261,0.0014946243,0.9923503,0.00013117141,0.00003229644,0.00008369737],"about_ca_topic_score_codex":0.00001333997,"about_ca_topic_score_gemma":0.000004977943,"teacher_disagreement_score":0.009361136,"about_ca_system_score_codex":0.000014121237,"about_ca_system_score_gemma":0.0000662742,"threshold_uncertainty_score":0.2256655},"labels":[],"label_agreement":null},{"id":"W166419983","doi":"10.15173/m.v1i20.786","title":"Allosteric Modulators: Potential Treatment for Schizophrenia","year":2012,"lang":"en","type":"article","venue":"The Meducator","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":true,"ca_institutions":"McMaster University","funders":"","keywords":"Schizophrenia (object-oriented programming); Presentation (obstetrics); Neuroscience; Psychiatry; Psychology; Allosteric regulation; Mental illness; Medicine; Mental health","score_opus":0.018396735028153605,"score_gpt":0.2707597517543167,"score_spread":0.2523630167261631,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W166419983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993815,0.0014635363,0.0030441014,0.00022026898,0.0010752588,0.00028230547,0.000012208732,0.000009070035,0.000078247474],"genre_scores_gemma":[0.99452984,0.000044754914,0.0020547812,0.00014937496,0.0020608203,0.00011628317,0.000048369497,0.000023490633,0.00097225606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993956,0.000031897744,0.00010138388,0.00014065797,0.00006336168,0.00026708833],"domain_scores_gemma":[0.99957645,0.0000075722724,0.00004107408,0.00025589124,0.000022273221,0.00009672623],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014397423,0.00011770847,0.00009089937,0.000014427797,0.00011534356,0.000017712062,0.00012750695,0.00006130672,0.00009746073],"category_scores_gemma":[0.000016027341,0.000073159725,0.000118606404,0.000028366649,0.000023707938,0.0000029818407,0.000031888754,0.000023827848,0.000023742754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000113856324,0.00010065951,0.00010017949,0.0000043917075,0.000071233306,7.590731e-8,0.00018979651,0.000011557769,0.9923586,0.00032628956,0.0011410437,0.005582295],"study_design_scores_gemma":[0.0006202492,0.00031844171,0.0003116924,0.0000041463654,0.000058296373,0.000015403415,0.00024851362,0.000049696548,0.91943127,0.00017514882,0.07860063,0.00016649844],"about_ca_topic_score_codex":0.000009485962,"about_ca_topic_score_gemma":0.0000012379891,"teacher_disagreement_score":0.07745959,"about_ca_system_score_codex":0.000017864244,"about_ca_system_score_gemma":0.000050172133,"threshold_uncertainty_score":0.29833668},"labels":[],"label_agreement":null},{"id":"W1665648490","doi":"10.3109/10799893.2015.1072977","title":"GPCR Retreat 2014: a good view leads to many discoveries!","year":2015,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University; Western University","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"G protein-coupled receptor; Biology; Signal transduction; Genetics","score_opus":0.014878144362405307,"score_gpt":0.24737431915501806,"score_spread":0.23249617479261275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1665648490","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9517338,0.0029969306,0.043107305,0.0005261655,0.0011772242,0.00012565794,0.0000073592764,0.0000055471323,0.00032001178],"genre_scores_gemma":[0.99365103,0.0015273175,0.0027162617,0.0001263853,0.0010819918,0.0000034484478,0.000011264608,0.000024120427,0.0008581951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989088,0.000085137675,0.00036265154,0.00020124113,0.0002583655,0.00018378434],"domain_scores_gemma":[0.99925315,0.000006677483,0.00015157681,0.0001015587,0.00019678373,0.00029027244],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053874904,0.00016355002,0.00025444705,0.000087016466,0.000066920846,0.00005355842,0.00010920743,0.00012967053,0.00029311108],"category_scores_gemma":[0.000022958651,0.00012951948,0.00014495464,0.00009620842,0.00003756591,0.000027283952,0.000017725217,0.00014229308,0.0000065586346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005493063,0.00006485871,0.00076457753,0.000022860653,0.000070572074,0.000005231786,0.00035408503,0.0002986536,0.9695881,0.00015856083,0.009062988,0.01906018],"study_design_scores_gemma":[0.0010945643,0.0037305283,0.00012704993,0.0000933982,0.00008167458,0.00033066186,0.0007205653,0.000019352992,0.723419,0.00032472087,0.26976147,0.00029700797],"about_ca_topic_score_codex":0.000009261345,"about_ca_topic_score_gemma":0.00000471509,"teacher_disagreement_score":0.2606985,"about_ca_system_score_codex":0.00002795823,"about_ca_system_score_gemma":0.000079514415,"threshold_uncertainty_score":0.5281651},"labels":[],"label_agreement":null},{"id":"W167052040","doi":"10.1016/b978-0-12-381517-0.00001-1","title":"Evolution of Genes for Incretin Hormones and their Receptors","year":2010,"lang":"en","type":"review","venue":"Vitamins and hormones","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Incretin; Hormone; Biology; Receptor; Glucagon-like peptide-1; Peptide hormone; Gene; Functional divergence; Internal medicine; Endocrinology; Genetics; Gene family; Medicine; Genome; Diabetes mellitus; Type 2 diabetes","score_opus":0.015381839914861346,"score_gpt":0.26306027875829024,"score_spread":0.2476784388434289,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W167052040","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014543578,0.98303264,0.0014862962,0.0000054422003,0.00022859524,0.00049844035,0.00015811417,0.000008216107,0.000038662307],"genre_scores_gemma":[0.0047470466,0.99315363,0.0011657464,0.000004418682,0.00038427676,0.00009655545,0.00024046419,0.00005003499,0.00015782274],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99888796,0.00004790577,0.0003753012,0.00042002194,0.00006213563,0.00020667579],"domain_scores_gemma":[0.9992873,0.00005836302,0.00026445612,0.00023214944,0.00007932854,0.00007839196],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025836856,0.00034504122,0.000778625,0.00010448271,0.00011448373,0.000029402143,0.00013236489,0.0005717193,0.0000059176446],"category_scores_gemma":[0.000053500546,0.00024575213,0.00023581198,0.000066930625,0.000114414244,0.000004737212,0.000118527314,0.000114431044,5.1760907e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017122295,0.000019004408,0.000010088484,0.0020721068,0.0000762511,1.4197984e-7,0.00003164315,7.541153e-8,0.10949592,0.00037575938,0.00015906936,0.8877428],"study_design_scores_gemma":[0.00018889343,0.00043990905,0.000011901034,0.00051791285,0.00017545462,0.000021124755,0.00011683309,0.00000861448,0.013138653,0.00014905713,0.98489136,0.00034027817],"about_ca_topic_score_codex":0.000022506865,"about_ca_topic_score_gemma":0.00002218228,"teacher_disagreement_score":0.9847323,"about_ca_system_score_codex":0.000007653266,"about_ca_system_score_gemma":0.00008728983,"threshold_uncertainty_score":0.99999946},"labels":[],"label_agreement":null},{"id":"W1672997779","doi":"10.53846/goediss-64","title":"Die Funktionelle Rolle der Palmitilierung des 5-HT 1A Rezeptor","year":2005,"lang":"de","type":"dissertation","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Ottawa","keywords":"Palmitoylation; Heterotrimeric G protein; Chemistry; G protein-coupled receptor; Receptor; Biochemistry; Cell biology; Biology; G protein; Cysteine; Molecular biology; Enzyme","score_opus":0.009873096747178794,"score_gpt":0.2517841895984619,"score_spread":0.2419110928512831,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1672997779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.872167,0.06615678,0.006953841,0.000101932594,0.0031054989,0.000986284,0.00012044846,0.00008471671,0.05032349],"genre_scores_gemma":[0.83008915,0.016802208,0.0063756485,0.0003966458,0.0033923844,0.00013888303,0.009579403,0.00021936529,0.13300629],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967614,0.00013967733,0.00079137215,0.001131553,0.00038999278,0.00078604696],"domain_scores_gemma":[0.9982802,0.00003155624,0.00034349356,0.0006255236,0.0004058124,0.00031338015],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003352439,0.0007533379,0.0005918949,0.00013440002,0.00060494017,0.00015686492,0.0004146848,0.0013106572,0.0077494048],"category_scores_gemma":[0.00009768503,0.00072925247,0.0005847348,0.00013843362,0.000094711,0.00001236913,0.00010844932,0.00037512646,0.00064338115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039693713,0.00024497855,0.00019738142,0.00022855548,0.00062914815,0.00001336389,0.0005319555,0.00022385303,0.9728517,0.00036158576,0.00401323,0.020307338],"study_design_scores_gemma":[0.0010009267,0.0005237593,0.00026855597,0.00019432821,0.0003189065,0.00000830392,0.0027679794,0.00040725383,0.82843804,0.0002043057,0.16476007,0.0011075438],"about_ca_topic_score_codex":0.0000771123,"about_ca_topic_score_gemma":0.0005290652,"teacher_disagreement_score":0.16074683,"about_ca_system_score_codex":0.00007746123,"about_ca_system_score_gemma":0.00027676095,"threshold_uncertainty_score":0.9999859},"labels":[],"label_agreement":null},{"id":"W167817790","doi":"10.1016/s0079-6123(09)17906-2","title":"NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia","year":2009,"lang":"en","type":"review","venue":"Progress in brain research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse; National Alliance for Research on Schizophrenia and Depression","keywords":"NMDA receptor; Neuroscience; Schizophrenia (object-oriented programming); Phencyclidine; Receptor; Gene knockdown; Glutamate receptor; Phenotype; Biology; Pharmacology; Psychology; Genetics; Psychiatry; Gene","score_opus":0.11730306395370826,"score_gpt":0.42658511953719735,"score_spread":0.3092820555834891,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W167817790","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005353053,0.99253696,0.000029023331,0.00010270074,0.000045197987,0.0012850926,0.00008451876,0.000004507072,0.0005589525],"genre_scores_gemma":[0.00428856,0.99126595,0.0031089557,0.000015899359,0.00010265433,0.00017859829,0.0000370875,0.00006256532,0.0009397322],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961145,0.001268555,0.00073806674,0.0006475168,0.0007302763,0.0005010939],"domain_scores_gemma":[0.9980438,0.00030524217,0.0003961473,0.00087090646,0.00030772577,0.00007620784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022241522,0.0002998221,0.0009337077,0.00027220513,0.00008668457,0.000030324949,0.0012371276,0.0004726348,0.000046804547],"category_scores_gemma":[0.00095652835,0.00020587537,0.0004609291,0.0006568412,0.000473448,0.0000045259426,0.0006337253,0.0006248608,0.000005303155],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001530691,0.00016944876,0.0000125628685,0.0037257907,0.00014919798,0.000004453816,0.00013280139,0.000035970184,0.0065365676,0.00057676993,0.00059069245,0.98791265],"study_design_scores_gemma":[0.0030315563,0.0021973026,0.000046840898,0.044716563,0.00041606292,0.00008911653,0.00051351474,0.0017159183,0.42270347,0.018220736,0.50423497,0.002113931],"about_ca_topic_score_codex":0.000029260793,"about_ca_topic_score_gemma":0.0000093910785,"teacher_disagreement_score":0.9857987,"about_ca_system_score_codex":0.000042047737,"about_ca_system_score_gemma":0.00072223664,"threshold_uncertainty_score":0.8395354},"labels":[],"label_agreement":null},{"id":"W171503647","doi":"10.1016/j.cyto.2013.06.070","title":"67","year":2013,"lang":"en","type":"article","venue":"Cytokine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Armed Forces; University of Toronto; Defence Research and Development Canada; St Joseph's Health Care; St. Michael's Hospital; Western University","funders":"","keywords":"CD14; CD16; DAPI; Receptor; Flow cytometry; Biology; Immune system; Antibody; Immunology; Cell; Molecular biology; CD3; Medicine; Staining; Pathology; Biochemistry","score_opus":0.006263713237981452,"score_gpt":0.209370723920712,"score_spread":0.20310701068273054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W171503647","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98870313,0.00020895073,0.004891134,0.00014173271,0.00014558416,0.000090728325,0.0000024131032,0.000012601287,0.005803751],"genre_scores_gemma":[0.99550986,0.000028186487,0.0012956855,0.0003409621,0.00027693348,0.000017379109,0.000033108714,0.0000107957,0.0024870879],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996336,0.000008916198,0.00006826531,0.0001272949,0.00004592263,0.0001159926],"domain_scores_gemma":[0.9997552,0.0000017258795,0.000017621269,0.00014537093,0.000035283763,0.000044779874],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003810054,0.000058183094,0.00004818839,0.000010976635,0.000029231674,0.000016500324,0.000076737226,0.000053247328,0.0012991689],"category_scores_gemma":[0.000014954118,0.000049488383,0.000035676734,0.000024472722,0.0000121483245,0.0000014288527,0.000036727863,0.000027928912,0.0002293342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000002410617,0.000008129421,0.00018860838,0.0000017343435,0.000006738046,3.8294135e-7,0.0000051573215,0.000006488091,0.98821586,0.0001790235,0.007750273,0.003635175],"study_design_scores_gemma":[0.00014039388,0.000076770826,0.0005344493,0.0000024650496,0.0000021859312,0.0000043749187,0.000016592696,0.00004675065,0.9030903,0.00032502125,0.09568032,0.000080360755],"about_ca_topic_score_codex":0.000014648449,"about_ca_topic_score_gemma":0.0000012467187,"teacher_disagreement_score":0.087930046,"about_ca_system_score_codex":0.0000025482839,"about_ca_system_score_gemma":0.000008843363,"threshold_uncertainty_score":0.99961376},"labels":[],"label_agreement":null},{"id":"W1722738490","doi":"10.1139/y2012-077","title":"Receptors and ionic transporters in nuclear membranes: new targets for therapeutical pharmacological interventions","year":2012,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec","keywords":"Crosstalk; Cytosol; Receptor; Cell biology; Membrane; Cell membrane; Nuclear membrane; Transporter; Chemistry; Biology; G protein-coupled receptor; Biophysics; Biochemistry; Nucleus","score_opus":0.061937425450074045,"score_gpt":0.34292591731237987,"score_spread":0.28098849186230584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1722738490","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007512752,0.9902964,0.0001237001,0.00011890026,0.0015197456,0.00038144845,0.00003600202,0.0000018329531,0.000009179513],"genre_scores_gemma":[0.028286764,0.96991867,0.00020100015,0.00037273884,0.001043046,0.000019579991,0.00006399082,0.000034939676,0.000059244037],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998408,0.00028024378,0.00057993544,0.00027081394,0.00003290341,0.00042807928],"domain_scores_gemma":[0.99898005,0.00007620104,0.000286095,0.0000590657,0.000045045446,0.0005535346],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00037545685,0.0002728257,0.00088886806,0.00021532038,0.00010303958,0.000010016989,0.00020868117,0.00055730407,0.0014196018],"category_scores_gemma":[0.000011839282,0.00022396966,0.00041690035,0.00006814005,0.00020462036,0.000009676347,0.000018872495,0.00044308393,0.0000015814304],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005780779,0.00022268669,0.000028996521,0.011379033,0.0031349396,0.00006793587,0.0006191202,0.000027443035,0.34664282,0.0006818261,0.0062265955,0.6303905],"study_design_scores_gemma":[0.0009935155,0.00064959156,0.0000059149,0.00035604925,0.001233996,0.00016514135,0.000044259305,0.0000051227357,0.0026551827,0.0002757846,0.9933525,0.00026294243],"about_ca_topic_score_codex":0.00004175587,"about_ca_topic_score_gemma":0.00015923682,"teacher_disagreement_score":0.98712593,"about_ca_system_score_codex":0.00003548948,"about_ca_system_score_gemma":0.0005688915,"threshold_uncertainty_score":0.99949324},"labels":[],"label_agreement":null},{"id":"W1727091879","doi":"10.1074/jbc.m108490200","title":"β-Arrestin/AP-2 Interaction in G Protein-coupled Receptor Internalization","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":154,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Arrestin; Endocytic cycle; Clathrin; Endocytosis; G protein-coupled receptor; Internalization; Cell biology; Clathrin adaptor proteins; Dynamin; Biology; Receptor; G protein; Signal transducing adaptor protein; Chemistry; Biochemistry; Signal transduction","score_opus":0.02470335657038491,"score_gpt":0.25204554921094413,"score_spread":0.22734219264055922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1727091879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955951,0.00058012945,0.002995131,0.00008932315,0.00016885488,0.00006811117,0.0000016952946,0.0000050742533,0.00049656205],"genre_scores_gemma":[0.9979257,0.00027350607,0.0008831382,0.00006400926,0.0005232718,0.0000051831644,0.000014956329,0.0000093984845,0.00030080968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990482,0.00004658018,0.00045145096,0.0001740308,0.00012029662,0.00015946687],"domain_scores_gemma":[0.99936676,0.000013270248,0.0003256241,0.00010345939,0.00011192666,0.000078946636],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00026208995,0.00012707234,0.00018480358,0.00002926657,0.000025340683,0.000023752504,0.0001905848,0.00022680647,0.0014685689],"category_scores_gemma":[0.00034372165,0.00009587591,0.00012799859,0.000082100436,0.00003339149,0.000008381542,0.000047103826,0.00023097802,0.000008310462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012396423,0.000101070334,0.0010898524,0.000012867859,0.000017265203,0.0000093908175,0.000019917814,0.00007482525,0.9968687,0.000004770901,0.0003077502,0.0013696002],"study_design_scores_gemma":[0.0005143384,0.0002975173,0.00011023368,0.00009464253,0.000004082802,0.000083344945,0.00007799553,0.00052932126,0.99183935,0.000087925226,0.0062300093,0.00013122415],"about_ca_topic_score_codex":0.0000025220788,"about_ca_topic_score_gemma":5.983461e-7,"teacher_disagreement_score":0.005922259,"about_ca_system_score_codex":0.000037963135,"about_ca_system_score_gemma":0.000013936715,"threshold_uncertainty_score":0.99944425},"labels":[],"label_agreement":null},{"id":"W1727134659","doi":"10.1007/978-3-642-28499-1_6","title":"Basis Function Discovery Using Spectral Clustering and Bisimulation Metrics","year":2012,"lang":"en","type":"book-chapter","venue":"Lecture notes in computer science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Computer science; Cluster analysis; Bisimulation; Adjacency list; Basis (linear algebra); Metric (unit); Spectral clustering; Theoretical computer science; Function (biology); State (computer science); Algorithm; Artificial intelligence; Data mining; Mathematics","score_opus":0.020651039434988232,"score_gpt":0.24438730358824695,"score_spread":0.22373626415325873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1727134659","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.035688315,0.0014408875,0.9617733,0.000011175759,0.00083914556,0.000116014446,0.000003199171,0.000007706698,0.000120287514],"genre_scores_gemma":[0.94587445,0.000121782534,0.052817527,0.00014897774,0.0009158603,7.998548e-7,0.000016034091,0.000024066563,0.000080497564],"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9988287,0.000012267067,0.0001817787,0.0005000212,0.00022575248,0.000251463],"domain_scores_gemma":[0.99952054,0.000029243101,0.00010751301,0.00022947782,0.00005205964,0.00006118805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031904673,0.0002078029,0.00016888398,0.00025032143,0.00011867011,0.0001493416,0.00016020334,0.0002310876,0.000014985587],"category_scores_gemma":[0.000027816382,0.00019330386,0.000056200537,0.00012379342,0.00010716188,0.00002856116,0.0002503019,0.00016691515,9.0790655e-7],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004425748,0.000014728505,0.0006214307,0.000052224128,0.000028751163,0.0000037331681,0.00010132564,0.16461253,0.39979511,0.000470729,0.0000017855697,0.43425336],"study_design_scores_gemma":[0.00052746217,0.000527974,0.00054117624,0.0002916223,0.000086124,0.00007575512,0.000001071682,0.7439848,0.23903148,0.01218822,0.0015664056,0.0011778676],"about_ca_topic_score_codex":0.000011478073,"about_ca_topic_score_gemma":0.00001992761,"teacher_disagreement_score":0.9101861,"about_ca_system_score_codex":0.000059047277,"about_ca_system_score_gemma":0.00006456634,"threshold_uncertainty_score":0.78827024},"labels":[],"label_agreement":null},{"id":"W1727217767","doi":"10.1111/j.1749-6632.2011.06039.x","title":"G protein–coupled receptor modulation with pepducins: moving closer to the clinic","year":2011,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Institute for Research in Immunology and Cancer","funders":"Tufts Medical Center","keywords":"Modulation (music); Chemistry; Biophysics; Physics; Biology; Acoustics","score_opus":0.08988356146925758,"score_gpt":0.3131809409857274,"score_spread":0.22329737951646983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1727217767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99457383,0.0004331986,0.00063359924,0.0035595791,0.00006855609,0.00034611634,0.0000024411795,0.0000042526635,0.0003784518],"genre_scores_gemma":[0.9939601,0.00005333232,0.0041432623,0.00077655696,0.00015460345,0.000008970972,4.990002e-7,0.0000073075294,0.0008954079],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893737,0.00006580755,0.00025252937,0.0002597735,0.00029467142,0.00018984456],"domain_scores_gemma":[0.9994748,0.000013770468,0.00025868,0.00014457841,0.000050358667,0.000057812602],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010018662,0.0001006956,0.0001269893,0.000032510805,0.00016283728,0.000012571418,0.00073809415,0.00009193272,0.000089481706],"category_scores_gemma":[0.00009979503,0.000050502193,0.00008914683,0.00027624497,0.0001969644,0.000011439414,0.00011840106,0.000089719455,0.000005690229],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009385188,0.00002272011,0.0004469203,0.000008169493,0.000025106234,1.1692004e-8,0.00050551526,0.000434188,0.99252766,0.000537949,0.0024739946,0.0029238833],"study_design_scores_gemma":[0.00009471058,0.00041676196,0.0021989732,0.00008437972,0.0000071638,7.1143967e-7,0.00026284362,0.00016285389,0.99150485,0.0014566206,0.0037200353,0.0000900895],"about_ca_topic_score_codex":0.000094566974,"about_ca_topic_score_gemma":0.0000069893463,"teacher_disagreement_score":0.003509663,"about_ca_system_score_codex":0.0000016463418,"about_ca_system_score_gemma":0.00006922255,"threshold_uncertainty_score":0.20594198},"labels":[],"label_agreement":null},{"id":"W1738288880","doi":"10.1111/bph.12705","title":"Identifying ligand‐specific signalling within biased responses: focus on δ opioid receptor ligands","year":2014,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Functional selectivity; G protein-coupled receptor; Opioid receptor; Confounding; Signalling; Opioid; Neuroscience; Computational biology; Analgesic; Focus (optics); Bioinformatics; Receptor; Medicine; Pharmacology; Computer science; Psychology; Biology; Internal medicine","score_opus":0.043054968996004396,"score_gpt":0.33805181361317727,"score_spread":0.29499684461717285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1738288880","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006594303,0.98584557,0.0023501806,0.000031994095,0.0046038185,0.0004322488,0.00006916622,0.000015355616,0.000057384397],"genre_scores_gemma":[0.0044045774,0.9883904,0.0011133383,0.00022784933,0.005182649,0.000033089455,0.00009064277,0.00015202252,0.0004054419],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99574846,0.00079997926,0.001842591,0.0006443632,0.000419854,0.00054476666],"domain_scores_gemma":[0.99690604,0.0002524005,0.0020408344,0.00018033807,0.00034001935,0.00028039346],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0023622403,0.00055616733,0.0019386595,0.0003856981,0.00026899006,0.00020393603,0.0008552153,0.0008028795,0.0004964673],"category_scores_gemma":[0.00021145932,0.0005746674,0.0011408034,0.00023472086,0.00010391755,0.000013491039,0.00014272872,0.0012523789,0.000053966993],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039976457,0.00016562142,3.2385134e-7,0.0015300433,0.00076585263,0.00055376824,0.00004650087,0.000037933274,0.47148776,0.00002422327,0.02465051,0.5003377],"study_design_scores_gemma":[0.0010673826,0.00097463647,1.1886505e-7,0.0074012387,0.00047367215,0.0022963686,0.00002386375,0.000003563926,0.26967925,0.000065789565,0.7175249,0.00048924476],"about_ca_topic_score_codex":0.000005669805,"about_ca_topic_score_gemma":0.0000026649386,"teacher_disagreement_score":0.6928744,"about_ca_system_score_codex":0.000102461236,"about_ca_system_score_gemma":0.00056090526,"threshold_uncertainty_score":0.9996705},"labels":[],"label_agreement":null},{"id":"W1753168678","doi":"10.1515/hmbci-2015-0032","title":"Role of the teneurins, teneurin C-terminal associated peptides (TCAP) in reproduction: clinical perspectives","year":2015,"lang":"en","type":"article","venue":"Hormone Molecular Biology and Clinical Investigation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"University of Toronto","keywords":"Biology; Gene; Multicellular organism; Chordate; Gamete; Genetics; Vertebrate; Cell biology; Bioinformatics; Computational biology","score_opus":0.03178093169877095,"score_gpt":0.33268512809179607,"score_spread":0.3009041963930251,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1753168678","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995779,0.0030634506,0.00016285897,0.00047375355,0.00018572247,0.00019436938,0.000004936226,0.000009317498,0.00012660144],"genre_scores_gemma":[0.99832493,0.00047032326,0.00063537864,0.00023309099,0.00019305342,0.000011633677,0.000040790288,0.000013067437,0.00007772762],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99760413,0.0008670002,0.00069026026,0.0005623383,0.000102493104,0.00017377528],"domain_scores_gemma":[0.99902654,0.000046887468,0.00029396234,0.00034773047,0.00016137709,0.00012350558],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00179348,0.0001441678,0.00027631127,0.000036849437,0.000053011907,0.000010338988,0.00017446988,0.00041263294,0.0000033701012],"category_scores_gemma":[0.0022658487,0.00011045387,0.00016002962,0.00013926961,0.0006243456,0.0000071172317,0.0001592943,0.00027826297,0.0000017742149],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000116619114,0.00019478983,0.28610584,0.0000032433195,0.00007325005,0.0000023281107,0.00011470715,0.000028525088,0.7092398,0.0018266771,0.00014693524,0.0021472762],"study_design_scores_gemma":[0.0027242876,0.0031159294,0.6092558,0.000051094234,0.0001105351,0.00004329837,0.0012997701,0.00046477542,0.34700394,0.03443601,0.0010455585,0.00044899565],"about_ca_topic_score_codex":0.000038137503,"about_ca_topic_score_gemma":0.000027521428,"teacher_disagreement_score":0.36223587,"about_ca_system_score_codex":0.00001203016,"about_ca_system_score_gemma":0.00012492514,"threshold_uncertainty_score":0.4504178},"labels":[],"label_agreement":null},{"id":"W1770207329","doi":"10.1136/bmj.h5411","title":"Paroxetine and Study 329: what we already knew and when","year":2015,"lang":"en","type":"letter","venue":"BMJ","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Chlorine Chemistry Council","funders":"","keywords":"Methyllycaconitine; Mecamylamine; Acetylcholine; Neuroscience; Nicotinic agonist; Nicotinic Antagonist; Chemistry; Inhibitory postsynaptic potential; Glutamate receptor; Biophysics; Depolarization; Postsynaptic potential; Acetylcholine receptor; Biology; Nicotinic acetylcholine receptor; Receptor; Pharmacology; Biochemistry","score_opus":0.029997658718857543,"score_gpt":0.2837314843136191,"score_spread":0.25373382559476154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1770207329","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2624991,0.08623296,0.00040349472,0.643004,0.0025613853,0.0034296992,0.00008808834,0.000067631794,0.0017136341],"genre_scores_gemma":[0.094202794,0.020447863,0.005179628,0.74374723,0.055665538,0.00067311036,0.0028792438,0.0006233824,0.07658123],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99865985,0.000116827745,0.00023954803,0.0005331584,0.00020485539,0.00024574442],"domain_scores_gemma":[0.9993303,0.000011318378,0.00012444374,0.0003671275,0.00007666664,0.000090155496],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037672272,0.00027541726,0.00030616648,0.000039924955,0.000054130545,0.00016669022,0.0001350432,0.00054164656,0.000065430824],"category_scores_gemma":[0.000039625484,0.00023598761,0.00004595368,0.000021207494,0.000041570398,0.000006042383,0.00021446521,0.00032069552,0.000009009044],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024489424,0.000024962786,0.00013940885,0.0000552155,0.00010930297,0.00007275357,0.00019288213,4.3502214e-7,0.009003377,0.0000015014083,0.98445064,0.005925004],"study_design_scores_gemma":[0.00061969814,0.00058022694,0.000018374412,0.00008757135,0.00007652647,0.000053173637,0.00047969338,0.0000060146835,0.0030167538,0.0002418056,0.9944669,0.0003532608],"about_ca_topic_score_codex":0.000039832685,"about_ca_topic_score_gemma":0.00001593252,"teacher_disagreement_score":0.16829629,"about_ca_system_score_codex":0.000007173138,"about_ca_system_score_gemma":0.000055589437,"threshold_uncertainty_score":0.96232957},"labels":[],"label_agreement":null},{"id":"W1776868030","doi":"10.1152/jn.2002.87.5.2612","title":"Role for G Protein Gβγ Isoform Specificity in Synaptic Signal Processing: A Computational Study","year":2002,"lang":"en","type":"article","venue":"Journal of Neurophysiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biophysics; Postsynaptic potential; Filter (signal processing); Biological system; Synapse; Noise (video); Chemistry; Neuroscience; Biology; Computer science; Receptor; Biochemistry; Artificial intelligence","score_opus":0.020106122319824383,"score_gpt":0.24878345802584165,"score_spread":0.22867733570601725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1776868030","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953723,0.00013170062,0.0040113847,0.00005823774,0.000057836496,0.0003236864,0.000002931672,0.0000027606916,0.000039151873],"genre_scores_gemma":[0.997797,0.0000100304815,0.001675341,0.000093301314,0.0003324784,0.000015131009,0.0000036400395,0.00001735258,0.00005571737],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9989815,0.00008823347,0.00041592953,0.00019727524,0.00012266317,0.0001944449],"domain_scores_gemma":[0.9994168,0.000018343273,0.0002615151,0.00007827331,0.00017162893,0.00005344091],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009828513,0.00012287621,0.00024317215,0.000088573135,0.000058295085,0.00001738106,0.00018147193,0.00007500309,0.0000690186],"category_scores_gemma":[0.000042378797,0.00010362208,0.00010432094,0.00008011586,0.00003361354,0.000008164941,0.000037044745,0.00015453287,0.0000030620893],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002880192,0.00051614206,0.000057775356,0.0000141392275,0.000031659325,0.000018154264,0.00010563597,0.01135938,0.98372215,0.000022794567,0.000036377187,0.0038277453],"study_design_scores_gemma":[0.02727963,0.11848915,0.057639334,0.00036324718,0.00028127205,0.0013167863,0.004379217,0.41342962,0.33681583,0.02149483,0.015824348,0.0026867362],"about_ca_topic_score_codex":0.0000015778653,"about_ca_topic_score_gemma":0.000001333105,"teacher_disagreement_score":0.6469064,"about_ca_system_score_codex":0.000014647647,"about_ca_system_score_gemma":0.000038647944,"threshold_uncertainty_score":0.42255855},"labels":[],"label_agreement":null},{"id":"W1778436929","doi":"10.1017/cbo9780511760334.006","title":"Signaling of dopamine receptor homo- and heterooligomers","year":2010,"lang":"en","type":"book-chapter","venue":"Cambridge University Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dopamine; Dopamine receptor; Computer science; Content (measure theory); Internet privacy; World Wide Web; Biology; Neuroscience; Mathematics","score_opus":0.010702316715206592,"score_gpt":0.18636451513974786,"score_spread":0.17566219842454128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1778436929","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.102981545,0.0010012393,0.0033905203,0.000007925245,0.00053541764,0.00049921236,0.00040241584,0.000040737494,0.891141],"genre_scores_gemma":[0.025245799,0.00043372455,0.0010651309,0.000025639561,0.00023134385,5.8922853e-7,0.00016563496,0.00006111385,0.97277105],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99899805,0.00002182816,0.00018893053,0.0004539041,0.00014380694,0.00019348445],"domain_scores_gemma":[0.99912435,0.000014784026,0.0002327089,0.0003582838,0.0001337925,0.00013605662],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009926127,0.0002922463,0.00033525415,0.00009317154,0.00009673553,0.000017140626,0.00025091897,0.00055955467,0.000019798093],"category_scores_gemma":[0.00000924375,0.00033598836,0.00017450462,0.000004379417,0.00022084196,0.0000036424701,0.0002828765,0.00029521537,0.0000020952427],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001211176,0.0000068346717,0.0000021206856,0.00008393939,0.00015104878,0.000010562437,0.000012653076,0.0000025357165,0.97136563,0.025859494,0.00091134367,0.0014727395],"study_design_scores_gemma":[0.00028765333,0.00012347377,5.622425e-7,0.00005864848,0.00006656358,0.0000074636973,0.000015392396,0.0000040038162,0.4652163,0.0000020753857,0.5339834,0.00023445304],"about_ca_topic_score_codex":0.000034696284,"about_ca_topic_score_gemma":0.0000015847945,"teacher_disagreement_score":0.53307205,"about_ca_system_score_codex":0.000015628111,"about_ca_system_score_gemma":0.00005294166,"threshold_uncertainty_score":0.9999092},"labels":[],"label_agreement":null},{"id":"W1781257988","doi":"10.1016/j.bpj.2015.08.001","title":"Molecular Simulations of Solved Co-crystallized X-Ray Structures Identify Action Mechanisms of PDEδ Inhibitors","year":2015,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"In silico; Small molecule; Molecular dynamics; Chemistry; hERG; Subfamily; Mechanism of action; Computational biology; Biophysics; Computational chemistry; Potassium channel; Biology; Biochemistry; Gene","score_opus":0.024761522803776154,"score_gpt":0.3078694817461852,"score_spread":0.2831079589424091,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1781257988","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8975789,0.00004169718,0.10192244,0.000020599802,0.0002926121,0.00008403662,0.000018530864,0.0000047608924,0.000036461268],"genre_scores_gemma":[0.9965482,0.0000122556,0.0030518463,0.000022782719,0.00028381692,0.00000131018,0.00003888894,0.00001910754,0.000021821425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988519,0.00009549202,0.00037080856,0.00016831052,0.00035113157,0.00016236669],"domain_scores_gemma":[0.9990755,0.000010741073,0.00031443336,0.00016394234,0.00028345134,0.00015194961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001777596,0.00013620788,0.00022578097,0.00006671506,0.00005530947,0.000025881965,0.00015046456,0.000140732,0.00004584281],"category_scores_gemma":[0.00007534505,0.000117501346,0.0002087833,0.00009430742,0.00005933062,0.000010950745,0.000044366676,0.00013034075,0.0000013785748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119103766,0.00007547092,0.000015320478,0.000011075108,0.00008074519,0.000002759984,0.00004610318,0.004739826,0.99366575,0.0008671632,0.00009627724,0.00028038255],"study_design_scores_gemma":[0.00078011805,0.00038622785,0.00006675536,0.000016702012,0.000038395996,0.000010139252,0.00017917225,0.00065205584,0.9925867,0.004951743,0.00021070358,0.000121338075],"about_ca_topic_score_codex":0.0000101606765,"about_ca_topic_score_gemma":9.604629e-7,"teacher_disagreement_score":0.0989693,"about_ca_system_score_codex":0.000017031825,"about_ca_system_score_gemma":0.00009657924,"threshold_uncertainty_score":0.47915658},"labels":[],"label_agreement":null},{"id":"W1786056679","doi":"10.1152/ajpgi.2000.279.5.g1059","title":"Human esophageal smooth muscle cells express muscarinic receptor subtypes M<sub>1</sub>through M<sub>5</sub>","year":2000,"lang":"en","type":"article","venue":"American Journal of Physiology-Gastrointestinal and Liver Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St Joseph's Health Centre; Lawson Health Research Institute; Western University","funders":"","keywords":"Muscarinic acetylcholine receptor; Smooth muscle; Receptor; Chemistry; Cell biology; Neuroscience; Biology; Endocrinology; Internal medicine; Medicine","score_opus":0.0065141090048850365,"score_gpt":0.21342373005691956,"score_spread":0.20690962105203453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1786056679","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986857,0.0004825828,0.00028640186,0.000047703714,0.00021819893,0.00015896819,0.00003141199,0.000020815758,0.00006817203],"genre_scores_gemma":[0.9941635,0.0009252182,0.003019382,0.00048123248,0.001247355,0.000012689321,0.000054651002,0.00006444504,0.000031517848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99699956,0.00048472692,0.00075976225,0.0007770434,0.00020821718,0.00077070063],"domain_scores_gemma":[0.9981839,0.00009232814,0.00077069417,0.0004013714,0.000261627,0.0002900738],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002636016,0.0005397088,0.0009034423,0.0001026591,0.00027964186,0.00003072868,0.0005011302,0.00014943031,0.0002805697],"category_scores_gemma":[0.000038201026,0.00047337962,0.000406047,0.00018561343,0.0010528454,0.00004339493,0.0001855974,0.00058132363,0.00005580801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005862302,0.00022780852,0.000053265103,0.00003001438,0.00010702361,0.000020372247,0.0001363343,0.00038525922,0.97853184,0.000055271943,0.0007483242,0.019118235],"study_design_scores_gemma":[0.0010827834,0.007972879,0.02475483,0.00012295748,0.00008997979,0.00029746012,0.00031008178,0.000048020564,0.9627986,0.00064054725,0.0013686741,0.0005131741],"about_ca_topic_score_codex":0.000053671272,"about_ca_topic_score_gemma":0.000006015612,"teacher_disagreement_score":0.024701566,"about_ca_system_score_codex":0.000031110758,"about_ca_system_score_gemma":0.00011165231,"threshold_uncertainty_score":0.9997718},"labels":[],"label_agreement":null},{"id":"W1786514222","doi":"10.1111/bph.12906","title":"Dopamine receptors –<scp>IUPHAR R</scp>eview 13","year":2014,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":521,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Saint Petersburg State University","keywords":"Dopamine; G protein-coupled receptor; Dopamine receptor D3; Dopamine receptor; D2-like receptor; D1-like receptor; Receptor; Neuroscience; Dopamine receptor D2; G protein-coupled receptor kinase; Biology; Pharmacology; Biochemistry","score_opus":0.02010082700795585,"score_gpt":0.3193034891131542,"score_spread":0.29920266210519836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1786514222","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00043207008,0.9930953,0.0007519328,0.000018299557,0.004850121,0.00040992672,0.000045074772,0.00001077868,0.00038654034],"genre_scores_gemma":[0.000075861084,0.9917052,0.00068807154,0.0003705745,0.005275546,0.00003317801,0.00014798646,0.00012820482,0.0015754191],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99605274,0.00091989164,0.0016212695,0.0005107957,0.00030371905,0.00059158483],"domain_scores_gemma":[0.9971134,0.00017683725,0.0018548496,0.00016545528,0.0003769464,0.00031250622],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015169628,0.00052765384,0.0023475913,0.00019513548,0.00013303483,0.00008441188,0.0009100114,0.0007275913,0.000878476],"category_scores_gemma":[0.0003890689,0.00053462817,0.0013235422,0.0002069324,0.00011412811,0.000011120282,0.00020796126,0.0009583463,0.00006944154],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006363352,0.00010034863,4.787787e-7,0.0031489942,0.0006972037,0.00027883376,0.000004920692,0.0000058031474,0.008478063,0.0000059744534,0.14829229,0.83898073],"study_design_scores_gemma":[0.0007551248,0.00054069364,2.2359164e-7,0.004092138,0.0012863103,0.008619137,0.000009237674,0.0000016161922,0.006210063,0.000015177467,0.97824425,0.00022603168],"about_ca_topic_score_codex":0.000007992723,"about_ca_topic_score_gemma":0.000004606221,"teacher_disagreement_score":0.8387547,"about_ca_system_score_codex":0.000062824925,"about_ca_system_score_gemma":0.0004552097,"threshold_uncertainty_score":0.9997105},"labels":[],"label_agreement":null},{"id":"W1789040068","doi":"10.1002/bmc.3121","title":"Pharmacokinetics of dronedarone in rat using a newly developed high‐performance liquid chromatographic assay method","year":2014,"lang":"en","type":"article","venue":"Biomedical Chromatography","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Chromatography; Pharmacokinetics; Dronedarone; Pharmacology","score_opus":0.0125843320577107,"score_gpt":0.2727679982266546,"score_spread":0.2601836661689439,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1789040068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85827804,0.0004461399,0.14057255,0.00004065534,0.00035449816,0.00018939974,0.0000091087895,0.000025703152,0.00008389257],"genre_scores_gemma":[0.93409806,0.0002880083,0.065074444,0.00015570756,0.00021932872,0.000019828414,0.00009354964,0.000043746273,0.000007323928],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99764395,0.00028171184,0.0006596487,0.0005052715,0.00042480306,0.00048463786],"domain_scores_gemma":[0.99906886,0.000044099117,0.00022194446,0.00035393162,0.00009185421,0.00021933483],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011702286,0.00030041466,0.0004589408,0.00048559418,0.00007722361,0.000017666038,0.00036726877,0.0003386157,0.000103495164],"category_scores_gemma":[0.00006943173,0.00027662265,0.00018210836,0.0010802529,0.00024533801,0.000010226776,0.00014597634,0.0001714044,0.0000027714702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012474153,0.00015621577,0.0016415756,0.00012499587,0.00007717577,0.000002817801,0.000033445933,0.00008109443,0.99394035,0.00012103218,0.0001675856,0.003528959],"study_design_scores_gemma":[0.0018044277,0.0008870962,0.00094695785,0.00014649914,0.000045076937,0.000028976183,0.000027993627,0.00595719,0.97834986,0.00007230853,0.011332785,0.0004008377],"about_ca_topic_score_codex":0.00006605008,"about_ca_topic_score_gemma":0.000006932917,"teacher_disagreement_score":0.075820014,"about_ca_system_score_codex":0.000013071897,"about_ca_system_score_gemma":0.000118815675,"threshold_uncertainty_score":0.9999686},"labels":[],"label_agreement":null},{"id":"W180273891","doi":"10.1016/b978-0-12-384921-2.00002-1","title":"Organizational Complexity of β-adrenergic Receptor Signaling Systems","year":2011,"lang":"en","type":"review","venue":"Current topics in membranes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Adrenergic receptor; Business; Receptor; Medicine; Internal medicine","score_opus":0.1019678306615573,"score_gpt":0.3212057026462288,"score_spread":0.21923787198467148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W180273891","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004795109,0.99650925,0.00035781204,0.0000014391617,0.0019415928,0.00036161274,0.00007079951,0.000010022139,0.00026797454],"genre_scores_gemma":[0.00042296693,0.9969977,0.0003404564,0.0000027632918,0.00089636096,0.000038799182,0.0010652022,0.000046836478,0.0001889112],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982137,0.00019752962,0.00076324586,0.0004346959,0.00016603318,0.00022481104],"domain_scores_gemma":[0.9990457,0.00001939118,0.00040032432,0.0003398767,0.00013262976,0.000062031664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028149373,0.00032993173,0.0009374815,0.00013374173,0.000044048145,0.000021052665,0.00041744902,0.0003508463,0.00029510935],"category_scores_gemma":[0.00006933388,0.0002901813,0.0002502866,0.00021447628,0.00009083587,0.0000031534648,0.00013168398,0.00022410894,0.000011113393],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057546742,0.00097516,0.00022774487,0.16785549,0.0007470621,0.0000076790375,0.0003858274,0.0003199986,0.012649872,0.14358725,0.0008630184,0.67232335],"study_design_scores_gemma":[0.00015584884,0.000046097866,5.0037875e-7,0.0044004093,0.000094373754,0.000007898873,0.000016385726,0.0000136126155,0.0041455226,0.000294582,0.9904696,0.00035519415],"about_ca_topic_score_codex":0.0000135339915,"about_ca_topic_score_gemma":0.0000034729405,"teacher_disagreement_score":0.98960656,"about_ca_system_score_codex":0.000027434126,"about_ca_system_score_gemma":0.00020145132,"threshold_uncertainty_score":0.99995506},"labels":[],"label_agreement":null},{"id":"W180462973","doi":"10.1007/978-1-61779-160-4_13","title":"Real-Time BRET Assays to Measure G Protein/Effector Interactions","year":2011,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Effector; Adenylyl cyclase; Förster resonance energy transfer; Ligand (biochemistry); Kinetics; Measure (data warehouse); Protein–protein interaction; Stimulation; Chemistry; Cell biology; Biophysics; Biology; Computational biology; Signal transduction; Receptor; Neuroscience; Biochemistry; Physics; Computer science; Data mining","score_opus":0.03129533463386948,"score_gpt":0.35562707879568495,"score_spread":0.3243317441618155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W180462973","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18106146,0.00010949738,0.8127367,0.000055549204,0.00029829782,0.0005664511,0.000013453587,0.00003067595,0.0051279203],"genre_scores_gemma":[0.07153349,0.00001357367,0.9271763,0.0002676713,0.000115119125,0.0002536269,0.000051099094,0.000052985633,0.0005361586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99721223,0.0013628742,0.0003272177,0.0006082601,0.00007597719,0.0004134482],"domain_scores_gemma":[0.9991406,0.000032858206,0.00008943693,0.0005047089,0.00009447726,0.00013791378],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001364632,0.00024619562,0.00030761247,0.00015842482,0.000054004904,0.000012770985,0.0003312934,0.00030228414,0.00046197698],"category_scores_gemma":[0.000500411,0.00023212838,0.00015223293,0.00021335193,0.000054658758,0.0000033975243,0.0001941837,0.00019524047,0.000065967564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000106396314,0.000060840124,0.0001307571,0.0000069711064,0.000050945757,0.000012312415,0.00008948763,0.000012300203,0.9923625,0.001219225,0.00009164192,0.0058566486],"study_design_scores_gemma":[0.0002783845,0.0005474124,0.0000843848,0.000024636118,0.000013489368,0.000018130992,0.00002199138,0.000064602464,0.9909712,0.0020647214,0.00562799,0.0002830552],"about_ca_topic_score_codex":0.00012609793,"about_ca_topic_score_gemma":0.000018550061,"teacher_disagreement_score":0.11443958,"about_ca_system_score_codex":0.00003088722,"about_ca_system_score_gemma":0.000055276632,"threshold_uncertainty_score":0.9465921},"labels":[],"label_agreement":null},{"id":"W1848707615","doi":"10.1042/bst20150065","title":"Probing the dynamic regulation of peripheral membrane proteins using hydrogen deuterium exchange–MS (HDX–MS)","year":2015,"lang":"en","type":"review","venue":"Biochemical Society Transactions","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Membrane; Hydrogen–deuterium exchange; Chemistry; Peripheral membrane protein; Signalling; Membrane protein; Cell biology; Enzyme; Membrane curvature; Biophysics; Biochemistry; Integral membrane protein; Lipid bilayer; Biology; Mass spectrometry; Chromatography","score_opus":0.031001642915596376,"score_gpt":0.29021585490205054,"score_spread":0.25921421198645417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1848707615","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.005736227,0.9198888,0.072307006,0.00002838345,0.00023675957,0.0015454808,0.0001719311,0.000035625144,0.00004976503],"genre_scores_gemma":[0.008230838,0.9835083,0.005946902,0.000029653007,0.0004789367,0.00032789286,0.0007938045,0.00014088511,0.0005428228],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981069,0.00013409149,0.00057255285,0.0005409112,0.00029625563,0.00034929835],"domain_scores_gemma":[0.9988979,0.000014159405,0.0003437322,0.00047651716,0.00014467392,0.00012302125],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037634218,0.000426424,0.0007257891,0.00002679206,0.00021436077,0.00003665985,0.00035417808,0.0008573,0.00016933077],"category_scores_gemma":[0.000010207688,0.00032182506,0.0012661617,0.0002681612,0.00020645048,0.000009713283,0.00004154571,0.00035294148,0.0000018089487],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014475503,0.0001051968,1.8860328e-7,0.003859849,0.0005955715,2.8171777e-7,0.00027668927,0.00019627406,0.961563,0.0000032846715,0.00019214094,0.03319304],"study_design_scores_gemma":[0.00048696258,0.00015927498,4.434973e-7,0.0021507405,0.0014724315,0.00006979282,0.00015351348,0.0030358094,0.32910493,0.000027131293,0.66244906,0.0008899223],"about_ca_topic_score_codex":0.000051886545,"about_ca_topic_score_gemma":0.000006880177,"teacher_disagreement_score":0.6622569,"about_ca_system_score_codex":0.00016245921,"about_ca_system_score_gemma":0.00031439477,"threshold_uncertainty_score":0.9999234},"labels":[],"label_agreement":null},{"id":"W1850749234","doi":"10.1002/cbin.10541","title":"Evidence of a role for <i>S. cerevisiae</i> α‐arrestin Art1 (Ldb19) in mating projection and zygote formations","year":2015,"lang":"en","type":"article","venue":"Cell Biology International","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Research Council (Canada); University of Saskatchewan","funders":"Medical Research Council; National Research Council Canada","keywords":"Cell biology; Internalization; Biology; Arrestin; Saccharomyces cerevisiae; Zygote; Mating; G protein-coupled receptor; Yeast; Receptor; Genetics; Signal transduction; Embryogenesis; Embryo","score_opus":0.03645451119445582,"score_gpt":0.29942517311538724,"score_spread":0.26297066192093144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1850749234","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97427,0.0010933697,0.022618756,0.00013374943,0.00027835218,0.00023002856,0.000023473569,0.000005505514,0.0013467708],"genre_scores_gemma":[0.993744,0.00009832828,0.0057589067,0.00005806036,0.000110746296,0.00004170077,0.00007698672,0.0000054292827,0.00010584417],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994775,0.000031087806,0.00020336245,0.00015127106,0.0000441253,0.0000926353],"domain_scores_gemma":[0.99964535,0.000030576237,0.00010844938,0.00006587778,0.000121585006,0.000028137338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002989981,0.00006467155,0.00008206646,0.000053008058,0.000021294589,0.0000093172885,0.000093406554,0.00008672073,0.000012958518],"category_scores_gemma":[0.00019652315,0.000060607897,0.000030294712,0.000034015073,0.000030807078,0.000009829602,0.000051100895,0.00004135656,0.0000013568954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008339242,0.000023658087,0.0044571827,0.000022012937,0.000010834819,1.2471297e-7,0.00015806004,0.00018549741,0.9890646,0.0005414201,0.00013859595,0.0053146444],"study_design_scores_gemma":[0.0010772448,0.00053946534,0.0003848211,0.000115352945,0.000010714222,0.000014408075,0.0005199645,0.0145673845,0.970197,0.002707641,0.00969536,0.0001706007],"about_ca_topic_score_codex":0.000022554024,"about_ca_topic_score_gemma":0.000017036884,"teacher_disagreement_score":0.019474003,"about_ca_system_score_codex":0.000012801311,"about_ca_system_score_gemma":0.000046375593,"threshold_uncertainty_score":0.24715184},"labels":[],"label_agreement":null},{"id":"W1861860658","doi":"10.1016/j.febslet.2015.10.022","title":"Molecular heterogeneity of midbrain dopaminergic neurons – Moving toward single cell resolution","year":2015,"lang":"en","type":"review","venue":"FEBS Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Alliance for Research on Schizophrenia and Depression; National Institute of Neurological Disorders and Stroke; Israel National Road Safety Authority; Fonds de Recherche du Québec - Santé; Michael J. Fox Foundation for Parkinson's Research","keywords":"Midbrain; Neuroscience; Neuron; Biology; Dopaminergic; Dopamine; Homogeneous; Cellular neuroscience; Cell type; Striatum; Cell; Central nervous system; Genetics","score_opus":0.04052759095270827,"score_gpt":0.27794871845350644,"score_spread":0.23742112750079816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1861860658","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.024209902,0.96982735,0.0047145374,0.000054272987,0.0005157021,0.0003926829,0.00006783121,0.000018972183,0.00019874268],"genre_scores_gemma":[0.008818988,0.98620766,0.002257275,0.0006659567,0.00055945787,0.00006741105,0.0010824946,0.00019170182,0.00014905215],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979355,0.00030283156,0.000530322,0.0006022655,0.00026104122,0.00036806625],"domain_scores_gemma":[0.99881387,0.000014800958,0.00041764978,0.0005580853,0.00006621948,0.00012936586],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031590962,0.00042107698,0.00082556886,0.00011487534,0.000040688377,0.00003056075,0.00039743577,0.00035261226,0.000013514756],"category_scores_gemma":[0.00004801442,0.00039641475,0.0005895036,0.00014549131,0.00006254671,0.0000041718185,0.00021370978,0.00020449102,0.000009907909],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011360688,0.00006620146,0.0000013779453,0.0027058234,0.00009666115,0.000030067315,0.000017250508,0.00019326193,0.9635614,0.000011135481,0.0027834396,0.030521976],"study_design_scores_gemma":[0.00019410039,0.0001895159,2.7661906e-7,0.00066075096,0.00023459761,0.000027691285,0.000008115632,0.000020611837,0.1436871,0.0000037648495,0.85453427,0.00043918117],"about_ca_topic_score_codex":0.000016549951,"about_ca_topic_score_gemma":0.0000021936714,"teacher_disagreement_score":0.85175085,"about_ca_system_score_codex":0.000057495297,"about_ca_system_score_gemma":0.000114303526,"threshold_uncertainty_score":0.9998488},"labels":[],"label_agreement":null},{"id":"W1863226311","doi":"10.1152/ajpheart.2001.281.6.h2337","title":"Angiotensin receptors: signaling, vascular pathophysiology, and interactions with ceramide","year":2001,"lang":"en","type":"review","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":258,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Angiotensin II; Receptor; Signal transduction; Endocrinology; Angiotensin II receptor type 1; Angiotensin receptor; Second messenger system; Internal medicine; G protein-coupled receptor; Cell biology; Biology; Chemistry; Medicine","score_opus":0.013650728636788638,"score_gpt":0.2634091904455369,"score_spread":0.24975846180874825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1863226311","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.25003493,0.74911803,0.000028064029,0.000027279868,0.000473914,0.00027745654,0.000015700334,0.000013964339,0.000010682199],"genre_scores_gemma":[0.037595026,0.95904106,0.0011192742,0.0004187805,0.0015307943,0.00002559046,0.00011811569,0.00011703775,0.00003431944],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99666506,0.0007971387,0.00088431267,0.0009362968,0.00015923817,0.0005579759],"domain_scores_gemma":[0.9974786,0.0001351783,0.0012912642,0.0005402152,0.00026554352,0.00028917662],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003510353,0.0007274272,0.00266079,0.00027146752,0.00020898653,0.000027787595,0.00030213484,0.000405714,0.000078891615],"category_scores_gemma":[0.000048069465,0.0005400668,0.0007170239,0.00029360832,0.0011274073,0.00002302516,0.00017310864,0.00080681196,0.0000071780123],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011260361,0.00008622244,0.000013840731,0.00038066806,0.0010090563,0.0000019090364,0.000047084308,0.000030930918,0.9426954,0.00002316909,0.00043944613,0.055159695],"study_design_scores_gemma":[0.0006822512,0.0038311854,0.0015948651,0.0017471185,0.0011293814,0.0011715059,0.0003002991,0.000008780997,0.00081680133,0.0004409209,0.9872548,0.0010221034],"about_ca_topic_score_codex":0.000022846543,"about_ca_topic_score_gemma":0.0000030953688,"teacher_disagreement_score":0.98681533,"about_ca_system_score_codex":0.000038886796,"about_ca_system_score_gemma":0.00028119315,"threshold_uncertainty_score":0.9997051},"labels":[],"label_agreement":null},{"id":"W1863660946","doi":"10.1152/ajpheart.2001.281.6.h2410","title":"Isoproterenol-induced cardiac hypertrophy: role of circulatory versus cardiac renin-angiotensin system","year":2001,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Quinapril; Losartan; Internal medicine; Endocrinology; Angiotensin II; Renin–angiotensin system; Medicine; Losartan Potassium; Plasma renin activity; Muscle hypertrophy; Circulatory system; Left ventricular hypertrophy; Angiotensin-converting enzyme; Blood pressure; ACE inhibitor","score_opus":0.0100458069126031,"score_gpt":0.22379900100854927,"score_spread":0.21375319409594618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1863660946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995861,0.0028089825,0.000007077618,0.000030654224,0.0010294162,0.00016598807,0.000012251402,0.000014131942,0.00007051351],"genre_scores_gemma":[0.998152,0.0002553666,0.00028699686,0.000091630805,0.0011269093,0.000008916444,0.000020934938,0.000049190618,0.000008036335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997636,0.00047555566,0.0006477038,0.0005548452,0.00020845157,0.00047741111],"domain_scores_gemma":[0.99814594,0.0000585787,0.0007012828,0.00054653635,0.00032796667,0.00021967635],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034715948,0.00035605987,0.0012220383,0.00014572525,0.00013541241,0.000009715397,0.00026299694,0.00025330303,0.000022628528],"category_scores_gemma":[0.000037286503,0.0003208252,0.0006269379,0.00019069712,0.00046421832,0.000018096389,0.00011230222,0.00031380387,0.0000066250573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006973818,0.000054155673,0.0011116173,0.000016881413,0.00059723866,6.57597e-7,0.00009146189,0.00008794186,0.99595577,0.00014090008,0.000091485475,0.0011545026],"study_design_scores_gemma":[0.0016765759,0.005121747,0.39606944,0.0000932888,0.00034779683,0.0001467514,0.0018847391,0.00009126322,0.5857283,0.0002869556,0.0078028725,0.0007503156],"about_ca_topic_score_codex":0.0000932206,"about_ca_topic_score_gemma":9.65484e-7,"teacher_disagreement_score":0.4102275,"about_ca_system_score_codex":0.000043911896,"about_ca_system_score_gemma":0.00017169295,"threshold_uncertainty_score":0.99992436},"labels":[],"label_agreement":null},{"id":"W188440186","doi":"10.1096/fasebj.21.5.a465-b","title":"Nucleus tractus solitarii (NTS) expression of GAD67 and neurokinin receptors (NK1‐R) in transgenic GAD67‐eGFP mice","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institutes of Health","keywords":"Glutamate decarboxylase; Solitary nucleus; Biology; Molecular biology; Receptor; Chemistry; Nucleus; Endocrinology; Internal medicine; Cell biology; Enzyme; Biochemistry; Medicine","score_opus":0.010022247344380116,"score_gpt":0.23836500437322125,"score_spread":0.22834275702884113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W188440186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953726,0.0009592514,0.0028327366,0.000075294985,0.000316086,0.000102695834,0.0000058388305,0.000003890376,0.00033162584],"genre_scores_gemma":[0.99792665,0.00071909896,0.0008393426,0.00012150124,0.00023467778,0.0000013932887,0.000006376532,0.000022811062,0.00012814702],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987645,0.00013063413,0.0004061679,0.00019760759,0.00018640886,0.00031468156],"domain_scores_gemma":[0.99944717,0.000042528973,0.00017043833,0.00016929377,0.00004690881,0.00012365324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001082799,0.00015242647,0.00017790058,0.00007507263,0.00012497074,0.000026111209,0.00023034819,0.00013805249,0.00015739253],"category_scores_gemma":[0.0000470969,0.000109552275,0.00011101277,0.000083521954,0.0000709406,0.000009667654,0.00004245812,0.00031317145,0.0000020978787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028434207,0.000050034003,0.0006237047,0.000008497239,0.00001622007,0.000009169361,0.0004904844,0.000066010674,0.9947562,0.000017918343,0.00015228504,0.0035251034],"study_design_scores_gemma":[0.0007760368,0.0002766372,0.0016208668,0.00005003443,0.000017485689,0.00013144594,0.00066943746,0.000025745867,0.9944809,0.00013450666,0.0016874794,0.0001294379],"about_ca_topic_score_codex":0.000018466273,"about_ca_topic_score_gemma":0.000022925704,"teacher_disagreement_score":0.0033956657,"about_ca_system_score_codex":0.000014468231,"about_ca_system_score_gemma":0.000046807934,"threshold_uncertainty_score":0.44674122},"labels":[],"label_agreement":null},{"id":"W1886006583","doi":"10.1523/jneurosci.20-23-08861.2000","title":"Brain-Stimulation Reward Thresholds Raised by an Antisense Oligonucleotide for the M5 Muscarinic Receptor Infused near Dopamine Cells","year":2000,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Air Force Office of Scientific Research; National Institute of Neurological Disorders and Stroke; National Institute on Aging","keywords":"Muscarinic acetylcholine receptor; Ventral tegmental area; Stimulation; Dopamine; Tegmentum; Endocrinology; Receptor; Muscarinic acetylcholine receptor M1; Neuroscience; Internal medicine; Chemistry; Biology; Psychology; Medicine; Central nervous system; Midbrain; Dopaminergic","score_opus":0.017031470838385156,"score_gpt":0.26744126222052095,"score_spread":0.2504097913821358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1886006583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925378,0.00013769578,0.005925205,0.0005209585,0.0006208695,0.00019264202,0.000016430877,0.0000060183115,0.00004241006],"genre_scores_gemma":[0.99604857,0.00031738894,0.0014203874,0.0013659276,0.00030029053,0.00000272342,0.000005780305,0.00002134678,0.00051758887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987992,0.000078153374,0.00036400382,0.0002543836,0.00026145787,0.00024280272],"domain_scores_gemma":[0.99917674,0.00007154742,0.00023936137,0.0002590489,0.00012486009,0.00012841252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060389197,0.00013480498,0.00015543333,0.00003088376,0.00026450644,0.00013130017,0.0004177459,0.00007599358,0.00008898613],"category_scores_gemma":[0.00016082019,0.00009604176,0.00014065111,0.0001385534,0.00012420578,0.000031640317,0.000029080187,0.00012598567,0.0000027546746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001705123,0.00005117754,0.0000687547,0.0000034191546,0.0000042791,0.0000023689424,0.00004286381,0.0060793245,0.98569304,0.000003826332,0.0036186976,0.0042617614],"study_design_scores_gemma":[0.0010126571,0.0017510384,0.0011063408,0.000014716785,0.000017436969,0.000058052185,0.000026436514,0.008863318,0.8251037,0.000026123353,0.1618505,0.00016971013],"about_ca_topic_score_codex":0.0000036240522,"about_ca_topic_score_gemma":0.0000011207535,"teacher_disagreement_score":0.16058934,"about_ca_system_score_codex":0.000009660519,"about_ca_system_score_gemma":0.00008216744,"threshold_uncertainty_score":0.39164695},"labels":[],"label_agreement":null},{"id":"W1908136873","doi":"10.1124/mol.59.5.1029","title":"Expression of Multiple Subtypes of Muscarinic Receptors and Cellular Distribution in the Human Heart","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Montreal Heart Institute","funders":"","keywords":"Muscarinic acetylcholine receptor; Gene isoform; Immunostaining; Receptor; Molecular biology; Acetylcholine receptor; Biology; Reverse transcription polymerase chain reaction; Antibody; Confocal microscopy; Messenger RNA; Immunofluorescence; Immunohistochemistry; Cell biology; Gene; Biochemistry; Genetics; Immunology","score_opus":0.011127985554724752,"score_gpt":0.27084216071877154,"score_spread":0.25971417516404677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1908136873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99661106,0.00091043685,0.0020364672,0.00007390801,0.00011073989,0.00018702209,0.0000070863525,0.0000029205921,0.000060373113],"genre_scores_gemma":[0.9994468,0.000114864015,0.00013805044,0.00010399291,0.000042945314,0.000017377077,0.00010989911,0.0000095616515,0.00001648929],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991101,0.00021937599,0.0002264201,0.00019987134,0.0000915191,0.00015272491],"domain_scores_gemma":[0.99967796,0.000020440224,0.00009002467,0.00014273215,0.000039622944,0.000029204182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030310426,0.00009743114,0.00015373954,0.000033947093,0.000038935166,0.0000035007033,0.00013603595,0.00011423304,0.00008371064],"category_scores_gemma":[0.000023626211,0.00007969431,0.00006405712,0.0000912908,0.00008388947,0.0000027352528,0.00006904254,0.000085261345,5.314897e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053776403,0.00008494252,0.005363795,0.000015847008,0.000012057511,0.000005343546,0.0000675641,0.00008646101,0.9937603,0.000058851678,0.0003133722,0.00017773107],"study_design_scores_gemma":[0.000655023,0.0002124641,0.0012570567,0.000009513098,0.000017927694,0.00000739864,0.000091204914,0.000058496174,0.9913563,0.00006949563,0.006188193,0.00007693432],"about_ca_topic_score_codex":0.000037185644,"about_ca_topic_score_gemma":0.0000050728604,"teacher_disagreement_score":0.0058748205,"about_ca_system_score_codex":0.0000056279328,"about_ca_system_score_gemma":0.000015067348,"threshold_uncertainty_score":0.32498398},"labels":[],"label_agreement":null},{"id":"W1914504104","doi":"10.1111/tra.12148","title":"<scp>CNIH4</scp> Interacts with Newly Synthesized <scp>GPCR</scp> and Controls Their Export from the Endoplasmic Reticulum","year":2014,"lang":"en","type":"article","venue":"Traffic","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Endoplasmic reticulum; Cell biology; COPII; Biology; ER retention; Receptor; Transport protein; Signal transduction; Golgi apparatus; Mutant; Secretory pathway; Biochemistry; Gene","score_opus":0.0066823915026743425,"score_gpt":0.19272750395993749,"score_spread":0.18604511245726313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1914504104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99391055,0.0010520557,0.0029810949,0.0000942212,0.0002127318,0.00036841887,0.00002535808,0.000051311265,0.0013042707],"genre_scores_gemma":[0.9970517,0.000242337,0.0008658904,0.00060293666,0.00043485328,0.00004978818,0.0000891819,0.000059205766,0.00060407846],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983022,0.00019295346,0.00030032475,0.00056403456,0.00019180078,0.0004486679],"domain_scores_gemma":[0.9984117,0.0006548381,0.00018654732,0.00050538476,0.000075720294,0.00016581154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040386975,0.00034555604,0.00037179983,0.00003019851,0.00018345792,0.0001345485,0.0003317887,0.00020320238,0.000022132075],"category_scores_gemma":[0.00046544816,0.00021570633,0.00012333842,0.00006976809,0.00013904295,0.000010598676,0.00008050049,0.00021783011,0.000019769448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047396876,0.000079417645,0.0003829901,0.000015101709,0.00023912138,0.000008643699,0.0009480715,0.00055813737,0.98720455,0.0002105084,0.0043551177,0.0059509375],"study_design_scores_gemma":[0.00244441,0.0007028542,0.00082852517,0.00010868204,0.00011414488,0.000062973304,0.0016495509,0.0030579958,0.88925225,0.00015493759,0.10149755,0.00012611208],"about_ca_topic_score_codex":0.000023938825,"about_ca_topic_score_gemma":0.00005348321,"teacher_disagreement_score":0.09795229,"about_ca_system_score_codex":0.0000088682455,"about_ca_system_score_gemma":0.000059611473,"threshold_uncertainty_score":0.8796249},"labels":[],"label_agreement":null},{"id":"W1920584780","doi":"10.1210/me.2015-1091","title":"Minireview: Role of Intracellular Scaffolding Proteins in the Regulation of Endocrine G Protein-Coupled Receptor Signaling","year":2015,"lang":"en","type":"review","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Biology; Heterotrimeric G protein; Scaffold protein; Signal transduction; Cell biology; G protein; Intracellular; Receptor; Cell signaling; Biochemistry","score_opus":0.02184527714937436,"score_gpt":0.2813752224027646,"score_spread":0.25952994525339024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1920584780","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020473009,0.97547734,0.0009376297,0.000021295338,0.00010929841,0.0028012835,0.000026384974,0.000011665707,0.00014207244],"genre_scores_gemma":[0.0345158,0.95957536,0.0039920006,0.000022857756,0.00021477419,0.000858239,0.0006047864,0.0001323533,0.00008383267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99582565,0.0009737415,0.0014563205,0.0007239628,0.00042267985,0.0005976342],"domain_scores_gemma":[0.99758965,0.000041951986,0.0010912819,0.00095742237,0.00024618302,0.00007348656],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000865354,0.0005722771,0.0017999541,0.0003077992,0.000044769087,0.0000171607,0.0008741754,0.00042491822,0.00008849421],"category_scores_gemma":[0.0002624629,0.00044438784,0.0006259692,0.00045680968,0.00014979712,0.000007284998,0.00025772175,0.00037273354,0.000008927792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002966969,0.00011215675,0.000001417797,0.0029255284,0.0001582393,0.000017507558,0.000056931345,0.00004241199,0.840289,0.0014627086,0.000021814858,0.15488264],"study_design_scores_gemma":[0.00038795295,0.00042032282,2.4049362e-7,0.0022428897,0.00022434846,0.00008778948,0.000090590656,0.000023195891,0.5151013,0.0002987169,0.48077205,0.000350603],"about_ca_topic_score_codex":0.00004842591,"about_ca_topic_score_gemma":0.0000057083116,"teacher_disagreement_score":0.48075023,"about_ca_system_score_codex":0.000052138374,"about_ca_system_score_gemma":0.00034259705,"threshold_uncertainty_score":0.9998008},"labels":[],"label_agreement":null},{"id":"W1923836518","doi":"10.1139/cjc-2015-0197","title":"Discovery of potential negative allosteric modulators of mGluR5 from natural products using pharmacophore modeling, molecular docking, and molecular dynamics simulation studies","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Pharmacophore; Chemistry; Allosteric regulation; Docking (animal); Molecular dynamics; Computational biology; Metabotropic glutamate receptor 5; Stereochemistry; Computational chemistry; Biochemistry; Metabotropic glutamate receptor; Receptor; Agonist; Medicine; Biology","score_opus":0.01898553321493234,"score_gpt":0.26635897274464215,"score_spread":0.2473734395297098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1923836518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839853,0.0080704335,0.0075552403,0.000028053835,0.0002369046,0.00006714589,0.000045218057,0.0000010218896,0.000010705725],"genre_scores_gemma":[0.9983189,0.00004475226,0.0014061157,0.000023317167,0.00014110458,4.7673785e-7,0.000033799308,0.000021900209,0.000009596574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899185,0.000036867605,0.00040747633,0.00019557808,0.00019607828,0.00017214684],"domain_scores_gemma":[0.99858385,0.000006500233,0.00039797585,0.00014576067,0.0006888936,0.00017698845],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001501874,0.00016663483,0.00029550272,0.000053712396,0.00003248386,0.000023268145,0.00015207016,0.00010996365,0.000002974354],"category_scores_gemma":[0.00020048881,0.00016214975,0.00009856949,0.0000855896,0.00010216315,0.000024278637,0.000043735035,0.00013373565,2.918677e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054191685,0.000007071772,0.00010145554,0.000046690966,0.0002025374,0.000029302251,0.00025188545,0.2384602,0.7607209,0.0000019724698,0.000005464402,0.000118335505],"study_design_scores_gemma":[0.0005036831,0.00005548936,0.0000050863637,0.000097302545,0.00008599964,0.00002936909,0.0007705342,0.1473935,0.8506397,0.00027838995,0.0000054748857,0.00013548198],"about_ca_topic_score_codex":0.00043152735,"about_ca_topic_score_gemma":0.000044149638,"teacher_disagreement_score":0.0910667,"about_ca_system_score_codex":0.00010323141,"about_ca_system_score_gemma":0.0008121902,"threshold_uncertainty_score":0.6612275},"labels":[],"label_agreement":null},{"id":"W193073533","doi":"10.1016/b978-0-12-394440-5.00006-1","title":"β-Arrestins","year":2013,"lang":"en","type":"review","venue":"Progress in molecular biology and translational science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"GTPase; Rab; Cell biology; Endocytic cycle; GTPase-activating protein; Effector; G protein-coupled receptor; G protein; Arrestin; Biology; Small GTPase; Signal transduction; Receptor; Chemistry; Biochemistry; Endocytosis","score_opus":0.023389547603756448,"score_gpt":0.36300296756376216,"score_spread":0.3396134199600057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W193073533","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007238834,0.9947429,0.003757985,0.000024588842,0.00013080848,0.00040724964,0.000015139215,0.0000070723318,0.00019037495],"genre_scores_gemma":[0.004150473,0.98673934,0.008638812,0.00003099258,0.00007294259,0.00017142363,0.00015925542,0.000019036146,0.000017723829],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99847454,0.000100768004,0.00030198824,0.0006588411,0.00013382813,0.00033003255],"domain_scores_gemma":[0.9995465,0.000018665338,0.00010203949,0.00018784679,0.00005312548,0.000091824244],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044048688,0.00024454118,0.00038798287,0.00016684827,0.00011494686,0.000044421526,0.00035738785,0.00032301372,0.000035766803],"category_scores_gemma":[0.000024909155,0.00019469752,0.00010937975,0.00029864503,0.00079131743,0.000006500173,0.00009260068,0.00018204909,0.00000687967],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000003048917,0.000026646454,0.0004980262,0.00033084146,0.000024224059,0.0000045215406,0.000007931274,0.0000018626525,0.0024152158,0.011073623,0.0000027076765,0.9856114],"study_design_scores_gemma":[0.00042713346,0.00024306918,0.00015412417,0.0013808922,0.00010984366,0.00010828084,0.0000073724814,0.00008800385,0.0032314637,0.0057283584,0.9875801,0.00094133033],"about_ca_topic_score_codex":0.0000029170099,"about_ca_topic_score_gemma":0.00000225084,"teacher_disagreement_score":0.98757744,"about_ca_system_score_codex":0.000006378587,"about_ca_system_score_gemma":0.00027631232,"threshold_uncertainty_score":0.7939535},"labels":[],"label_agreement":null},{"id":"W1935396040","doi":"10.1080/19336950.2015.1018000","title":"The unusual suspects: Regulation of retinal calcium channels by somatostatin","year":2015,"lang":"en","type":"letter","venue":"Channels","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Michael Smith Health Research BC; University of British Columbia; Carleton University","funders":"","keywords":"Somatostatin; Chemistry; Calcium; Biophysics; Cell biology; Neuroscience; Biology","score_opus":0.0201087604344831,"score_gpt":0.2571969478806965,"score_spread":0.23708818744621343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1935396040","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.28205067,0.038717862,0.058868278,0.56697136,0.03275568,0.006644476,0.002943122,0.00034811924,0.010700431],"genre_scores_gemma":[0.61965215,0.0012830561,0.0010032507,0.15431128,0.05707838,0.0005122378,0.023572238,0.00090340973,0.14168397],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99789226,0.0001846326,0.0004722654,0.000506321,0.00046112173,0.0004833953],"domain_scores_gemma":[0.99856585,0.000048714017,0.00043040045,0.0005262734,0.0003489499,0.00007982262],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005461499,0.0003565408,0.0003549444,0.00005423701,0.00015707371,0.00007488108,0.0004539855,0.0008698501,0.00006770964],"category_scores_gemma":[0.00013229376,0.0002752125,0.00018309701,0.00010379952,0.00014442079,0.000004660207,0.00014327027,0.00046467548,0.000015059095],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036493773,0.000010048146,0.0000018031667,0.00004571135,0.000057860223,0.00000482912,0.00009051793,0.000031155567,0.2244703,0.00004731634,0.77497166,0.00023229994],"study_design_scores_gemma":[0.00023736423,0.0002419831,6.559476e-7,0.00005049055,0.000022705231,0.000013062153,0.00008834288,0.00010313842,0.4830837,0.00087176915,0.5150429,0.00024387932],"about_ca_topic_score_codex":0.00002858508,"about_ca_topic_score_gemma":0.000001502529,"teacher_disagreement_score":0.4126601,"about_ca_system_score_codex":0.00003622115,"about_ca_system_score_gemma":0.00014608713,"threshold_uncertainty_score":0.99997},"labels":[],"label_agreement":null},{"id":"W1940077133","doi":"10.1080/1062936x.2015.1088572","title":"Molecular modelling studies on 2-substituted octahydropyrazinopyridoindoles for histamine H<sub>2</sub>receptor antagonism","year":2015,"lang":"en","type":"article","venue":"SAR and QSAR in environmental research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Department of Science and Technology, Ministry of Science and Technology, India; Ottawa Hospital Research Institute","keywords":"Homology modeling; Histamine; Receptor; Antagonism; G protein-coupled receptor; In silico; Chemistry; Histamine receptor; Homology (biology); Binding site; Biochemistry; Pharmacology; Amino acid; Biology; Antagonist; Gene; Enzyme","score_opus":0.07042194872467117,"score_gpt":0.32932544763819865,"score_spread":0.2589034989135275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1940077133","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919898,0.0046730936,0.0025076324,0.00007303756,0.00016007171,0.00046395618,0.00005262141,0.000006847965,0.000072964445],"genre_scores_gemma":[0.9958665,0.002645115,0.0009263567,0.000063576656,0.00015490664,0.000058071106,0.00018626888,0.000038986833,0.000060266764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982462,0.00013000816,0.00024411909,0.0005303686,0.0003995169,0.000449765],"domain_scores_gemma":[0.999471,0.000047184458,0.000041854666,0.0002332534,0.000032584783,0.00017411467],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009945222,0.00019792629,0.00021325448,0.00012704045,0.00014532414,0.0000297919,0.00015087267,0.0001524439,0.000004274236],"category_scores_gemma":[0.00009298175,0.00018546665,0.00006713549,0.000075063865,0.00025515968,0.000009357406,0.00017616335,0.00020771082,0.000017259994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003154843,0.00013162286,0.00012563464,0.000024627121,0.00004216711,0.00000977491,0.00019358045,0.0065324623,0.9899839,0.00024657763,0.00019562658,0.0021985425],"study_design_scores_gemma":[0.0011172462,0.00062908564,0.0000122734755,0.000033703705,0.0000063851935,0.000003837946,0.001083539,0.0046125413,0.9882954,0.00073056587,0.003262634,0.00021278634],"about_ca_topic_score_codex":0.000006951371,"about_ca_topic_score_gemma":0.000003558748,"teacher_disagreement_score":0.0038766768,"about_ca_system_score_codex":0.000118075266,"about_ca_system_score_gemma":0.00004391629,"threshold_uncertainty_score":0.75631106},"labels":[],"label_agreement":null},{"id":"W1940693634","doi":"10.1073/pnas.1508836112","title":"Receptor sequestration in response to β-arrestin-2 phosphorylation by ERK1/2 governs steady-state levels of GPCR cell-surface expression","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Government of Canada; Human Frontier Science Program; National Institutes of Health; Ministry of Education, India; Ministry of Earth Sciences","keywords":"G protein-coupled receptor; Cell biology; G protein-coupled receptor kinase; Biology; Arrestin; Receptor; Signal transduction; Protein kinase A; Kinase; Chemistry; Biochemistry","score_opus":0.04175553390792171,"score_gpt":0.2983438529039576,"score_spread":0.2565883189960359,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1940693634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99867225,0.00013821178,0.00006326233,0.00041273495,0.000026431188,0.00017411556,0.00005272542,0.0000026154414,0.00045764155],"genre_scores_gemma":[0.99443245,0.000014164927,0.0051423125,0.000055741337,0.0000230828,0.0000044483836,9.812853e-7,0.0000046465925,0.00032217696],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99862957,0.000024247998,0.000314828,0.00022293272,0.00069711695,0.00011130383],"domain_scores_gemma":[0.99926716,0.000034754376,0.0003594611,0.000011988069,0.00027881283,0.000047840702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020595344,0.00008203056,0.00010890686,0.000050557854,0.000046548892,0.000012531376,0.00034705736,0.00009312619,0.000009709503],"category_scores_gemma":[0.00059591566,0.000062810715,0.000034270124,0.00031174015,0.000117137635,0.00003627587,0.00008894597,0.00007254637,7.559798e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020845488,0.000028484912,0.0011876817,0.0000144543665,0.0000020195985,1.6535483e-9,0.0002731027,0.0020712223,0.99467885,0.00014553737,0.0013110092,0.00007919483],"study_design_scores_gemma":[0.0002144659,0.00017642094,0.002576376,0.00007126095,0.0000018902748,4.1178956e-7,0.00028702553,0.00030976528,0.9945369,0.0013969886,0.00035717047,0.00007135576],"about_ca_topic_score_codex":0.000011648699,"about_ca_topic_score_gemma":1.3309564e-7,"teacher_disagreement_score":0.00507905,"about_ca_system_score_codex":0.000033341905,"about_ca_system_score_gemma":0.00007973443,"threshold_uncertainty_score":0.25613466},"labels":[],"label_agreement":null},{"id":"W1955145476","doi":"10.1152/ajpheart.2001.281.2.h931","title":"Cardiac-directed overexpression of wild-type α<sub>1B</sub>-adrenergic receptor induces dilated cardiomyopathy","year":2001,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"Canadian Institutes of Health Research","keywords":"Phospholamban; Internal medicine; Dilated cardiomyopathy; Titin; Cardiomyopathy; Heart failure; Endocrinology; Cardiac function curve; Myosin; Receptor; Medicine; Cardiology; Biology; Myocyte; Cell biology; Sarcomere","score_opus":0.00793533970035184,"score_gpt":0.22370748050479372,"score_spread":0.21577214080444188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1955145476","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973943,0.0017598688,0.000005485783,0.000023987814,0.0006364283,0.00011031129,0.000012501911,0.000016705519,0.000040399034],"genre_scores_gemma":[0.99720556,0.001628127,0.00015914394,0.00019602668,0.00070320925,0.0000047692415,0.000056180288,0.00003942544,0.0000075362864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978473,0.0004978483,0.0006087928,0.00044358874,0.00019450158,0.0004079284],"domain_scores_gemma":[0.99826145,0.00005438072,0.0007235288,0.00038617087,0.00037638226,0.00019807726],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003202055,0.00032640112,0.0010083986,0.00014913428,0.00012347332,0.000009533763,0.00025813276,0.00025332253,0.00004595834],"category_scores_gemma":[0.00005234887,0.00027968464,0.00037512157,0.00031522595,0.0005218493,0.000022811493,0.00015875886,0.00030891364,0.000004708655],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00066828105,0.000104423394,0.0007385764,0.000018894272,0.000328772,3.6825173e-7,0.000093527524,0.00025665373,0.9961193,0.00001633935,0.00048274823,0.0011720749],"study_design_scores_gemma":[0.00072115654,0.0023399945,0.10830145,0.00007469772,0.00008174099,0.000066516935,0.0003321793,0.000023505916,0.8852941,0.00022365642,0.0022051549,0.00033588486],"about_ca_topic_score_codex":0.000026585089,"about_ca_topic_score_gemma":5.383895e-7,"teacher_disagreement_score":0.11082528,"about_ca_system_score_codex":0.000022076732,"about_ca_system_score_gemma":0.00015086656,"threshold_uncertainty_score":0.99996555},"labels":[],"label_agreement":null},{"id":"W1959970989","doi":"10.1111/jnc.13366","title":"The effect of phosphorylation on arrestin–rhodopsin interaction in the squid visual system","year":2015,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canada Excellence Research Chairs, Government of Canada; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Arrestin; Rhodopsin; Phosphorylation; Visual phototransduction; Biophysics; Protein kinase A; Serine; Kinase; Chemistry; Biology; Biochemistry; Cell biology; G protein-coupled receptor; Receptor; Retinal","score_opus":0.01214744485426257,"score_gpt":0.2791733921932108,"score_spread":0.26702594733894824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1959970989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985066,0.00027110122,0.00020164969,0.00006293103,0.0004012315,0.000062893996,6.5021715e-7,0.0000015819453,0.0004913704],"genre_scores_gemma":[0.99956477,0.000020891752,0.000020916794,0.000025196518,0.00033066177,0.0000025451852,0.0000028691215,0.000008260679,0.000023864819],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990785,0.00017578053,0.00031783144,0.00009030117,0.00024262052,0.00009493123],"domain_scores_gemma":[0.9992468,0.00012252602,0.00035485977,0.00013515017,0.000100478464,0.00004018034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094811025,0.00009174377,0.00012282524,0.000018936002,0.00003933549,0.00002603667,0.00020803114,0.00006948159,0.0000016021355],"category_scores_gemma":[0.0004042948,0.000050367573,0.00009356201,0.00006341555,0.000022844877,0.000004517887,0.000020877262,0.00019673289,8.590102e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00074684253,0.00002135453,0.00033117677,0.00002698023,0.00001287155,0.000010791337,0.000044858392,0.0006981225,0.9966011,0.0000063069174,0.00049725623,0.0010023179],"study_design_scores_gemma":[0.0005437572,0.0013606135,0.0003142735,0.00008661774,0.00001497983,0.00019064917,0.0005059946,0.0002735243,0.995494,0.000007555012,0.001158689,0.000049311988],"about_ca_topic_score_codex":0.0000021850128,"about_ca_topic_score_gemma":4.849488e-7,"teacher_disagreement_score":0.001339259,"about_ca_system_score_codex":0.000025524985,"about_ca_system_score_gemma":0.000041718147,"threshold_uncertainty_score":0.205393},"labels":[],"label_agreement":null},{"id":"W1963422225","doi":"10.1124/mol.60.6.1243","title":"Agonist-Stimulated and Tonic Internalization of Metabotropic Glutamate Receptor 1a in Human Embryonic Kidney 293 Cells: Agonist-Stimulated Endocytosis Is β-Arrestin1 Isoform-Specific","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"G protein-coupled receptor; Metabotropic glutamate receptor; Cell biology; Internalization; Biology; Metabotropic receptor; HEK 293 cells; Metabotropic glutamate receptor 7; Receptor; Chemistry; Agonist; Biochemistry; Signal transduction","score_opus":0.011441244714994686,"score_gpt":0.2739181877877286,"score_spread":0.2624769430727339,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963422225","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98495173,0.003236394,0.009950853,0.0002311546,0.0008316253,0.0005545811,0.000054617474,0.00003927108,0.00014979736],"genre_scores_gemma":[0.995366,0.0019587923,0.000776059,0.0009660642,0.00013383484,0.000051703784,0.00031399916,0.00008064347,0.0003529318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973406,0.00031042413,0.0007148763,0.0007865187,0.00022193402,0.0006256232],"domain_scores_gemma":[0.9988598,0.000022429082,0.00032883318,0.00036240052,0.00017669624,0.00024980988],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027770104,0.00043350522,0.0005504472,0.00024768902,0.00014549877,0.00004909242,0.00037472244,0.0003634309,0.0015651317],"category_scores_gemma":[0.000027814565,0.00045935655,0.00019468219,0.00034477413,0.00017281681,0.000017999539,0.00023609654,0.00028032056,0.000021607299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040385625,0.00018953126,0.00042567067,0.000065895445,0.00021705758,0.000074024145,0.00009544003,0.0022902424,0.99392825,0.00013368374,0.0014333205,0.000743034],"study_design_scores_gemma":[0.0029721963,0.00065077085,0.000085386084,0.000050541323,0.00011911251,0.000027415263,0.000021153963,0.003575292,0.9496588,0.00012359995,0.04230094,0.00041474984],"about_ca_topic_score_codex":0.000085314954,"about_ca_topic_score_gemma":0.000007224133,"teacher_disagreement_score":0.0442694,"about_ca_system_score_codex":0.000074954325,"about_ca_system_score_gemma":0.000116874086,"threshold_uncertainty_score":0.99978584},"labels":[],"label_agreement":null},{"id":"W1964058127","doi":"10.1016/j.bbalip.2006.02.015","title":"Contribution of lipid mediators to the regulation of phosphatidylcholine synthesis by angiotensin","year":2006,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Heart and Stroke Foundation of Canada","keywords":"Angiotensin II; Phosphatidic acid; Diacylglycerol kinase; Arachidonic acid; Angiotensin II receptor type 1; Chemistry; Biochemistry; Internal medicine; Signal transduction; Endocrinology; Receptor; Protein kinase C; Biology; Enzyme; Phospholipid","score_opus":0.0032293061068591456,"score_gpt":0.2045787677312269,"score_spread":0.20134946162436776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964058127","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953133,0.00094584684,0.0024827856,0.00056118966,0.00013469078,0.00026735634,0.00017408085,0.000007081396,0.00011365603],"genre_scores_gemma":[0.99826795,0.00022307778,0.0007672406,0.00013655768,0.0001589214,0.000013888599,0.00038756058,0.000021344395,0.000023443941],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986015,0.00018280504,0.00048345525,0.00036713012,0.00013976452,0.00022532126],"domain_scores_gemma":[0.99895173,0.000055467866,0.0003768199,0.0003533199,0.00020100207,0.00006163332],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030403511,0.00022075565,0.00038848256,0.0000682728,0.000051980183,0.0000074031436,0.00022079198,0.00026804197,0.000013588925],"category_scores_gemma":[0.00008083337,0.00017162376,0.00019608477,0.00017950874,0.00023817603,0.00000535207,0.00010476273,0.000074482974,7.8809603e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001558497,0.00012331438,0.000038030284,0.000021962553,0.00006842262,7.845055e-8,0.000031162395,0.000027087128,0.9977924,0.0004958622,0.00090067176,0.00034513502],"study_design_scores_gemma":[0.00037625557,0.00045432564,0.00063334126,0.00002510734,0.000079607904,0.000001028447,0.000023587338,0.000057457248,0.9964056,0.0001364721,0.001631061,0.00017612538],"about_ca_topic_score_codex":0.00007757302,"about_ca_topic_score_gemma":0.0000033833114,"teacher_disagreement_score":0.0029546525,"about_ca_system_score_codex":0.000006593918,"about_ca_system_score_gemma":0.000042080912,"threshold_uncertainty_score":0.69986135},"labels":[],"label_agreement":null},{"id":"W1964225232","doi":"10.3389/fendo.2012.00105","title":"BRET biosensors to study GPCR biology, pharmacology, and signal transduction","year":2012,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Compagnia di San Paolo; F. Hoffmann-La Roche","keywords":"G protein-coupled receptor; Signal transduction; Receptor; Biosensor; Cell biology; Biology; Transduction (biophysics); Arrestin; G protein; Chemistry; Computational biology; Biochemistry","score_opus":0.0113249274032447,"score_gpt":0.27560176167942385,"score_spread":0.26427683427617915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964225232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97882503,0.0019803827,0.016208999,0.00021125177,0.0022035479,0.0004334668,0.000011128152,0.00001905544,0.00010715218],"genre_scores_gemma":[0.99292785,0.00023877066,0.0058590434,0.00032408573,0.00045022162,0.00007245935,0.000022804388,0.000020958274,0.000083789826],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850553,0.00022522183,0.00022883629,0.00039451572,0.000049286788,0.00059659104],"domain_scores_gemma":[0.999641,0.000009332572,0.000043955984,0.0001460215,0.000024332174,0.00013536889],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021106905,0.00018453448,0.00024565443,0.00018855679,0.000062058156,0.0000069837056,0.00014558034,0.00015179918,0.00014211623],"category_scores_gemma":[0.000016178514,0.00018298012,0.000044021304,0.0001194876,0.00010245435,0.0000072277567,0.00009126163,0.0001552977,0.0000064791784],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002280945,0.00031300107,0.14878449,0.000005952664,0.000140807,0.0000075887015,0.0007027296,0.00003721756,0.8306467,0.00014846503,0.0030968864,0.01588805],"study_design_scores_gemma":[0.0025964498,0.0018749809,0.013566724,0.000004415425,0.000078143385,0.00011906681,0.0032886597,0.000056829966,0.91982144,0.0004401228,0.057640623,0.0005125507],"about_ca_topic_score_codex":0.000029602359,"about_ca_topic_score_gemma":0.000007852041,"teacher_disagreement_score":0.13521776,"about_ca_system_score_codex":0.00002036288,"about_ca_system_score_gemma":0.000014303292,"threshold_uncertainty_score":0.7461713},"labels":[],"label_agreement":null},{"id":"W1964280588","doi":"10.1016/j.schres.2008.05.014","title":"Reduced prefrontal cortex DARPP-32 mRNA in completed suicide victims with schizophrenia","year":2008,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Prefrontal cortex; Schizophrenia (object-oriented programming); Dopaminergic; Single-nucleotide polymorphism; SNP; Psychology; Internal medicine; Neuroscience; Endocrinology; Biology; Medicine; Dopamine; Psychiatry; Genotype; Genetics; Gene","score_opus":0.04980284247110338,"score_gpt":0.3136668303069855,"score_spread":0.2638639878358821,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964280588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996228,0.00074313115,0.00030113923,0.00014496333,0.0001408254,0.000624531,0.000031136864,0.00004106314,0.0017452345],"genre_scores_gemma":[0.9932564,0.0002265833,0.0047851126,0.000047935155,0.00040912838,0.000106499,0.00024490998,0.00008584254,0.00083760923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962483,0.00039351315,0.00044739596,0.00095584634,0.00092150597,0.001033426],"domain_scores_gemma":[0.99842536,0.000055975383,0.00009229883,0.0007782196,0.00033242445,0.000315708],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00087425817,0.00034706472,0.0003907972,0.00036171547,0.00048804778,0.00007342554,0.0006534283,0.00029386356,0.00032379734],"category_scores_gemma":[0.00014150408,0.0003026575,0.00011455945,0.0006940427,0.00040401827,0.000019382132,0.00032578124,0.00082969235,0.000101316255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0056317756,0.0001490672,0.0014809758,0.000017988712,0.000062811894,0.00014031683,0.00012976288,0.00007471399,0.9891352,0.00026804497,0.0007389472,0.002170363],"study_design_scores_gemma":[0.012006003,0.0029705106,0.08086009,0.00023206515,0.000019990139,0.00052483456,0.00048154022,0.0012076714,0.8954791,0.00071822543,0.0042847153,0.0012152515],"about_ca_topic_score_codex":0.0004293369,"about_ca_topic_score_gemma":0.0007472935,"teacher_disagreement_score":0.09365613,"about_ca_system_score_codex":0.00009511109,"about_ca_system_score_gemma":0.0006458496,"threshold_uncertainty_score":0.99994254},"labels":[],"label_agreement":null},{"id":"W196429121","doi":"10.1007/978-1-59259-919-6_13","title":"The Role of Oligomerization in G Protein-Coupled Receptor Maturation","year":2005,"lang":"en","type":"book-chapter","venue":"Contemporary clinical neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse; Canada Research Chairs","keywords":"G protein-coupled receptor; Receptor; Cell biology; Signal transduction; Cell surface receptor; Rhodopsin-like receptors; Biology; Tyrosine kinase; Receptor tyrosine kinase; Chemistry; Glycoprotein 130; Biochemistry; Agonist; Metabotropic receptor","score_opus":0.031282592264560954,"score_gpt":0.2857767020859048,"score_spread":0.2544941098213438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W196429121","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5123404,0.031856287,0.007494147,0.0029123558,0.009858454,0.011061594,0.00028084675,0.00017586326,0.42402005],"genre_scores_gemma":[0.93430656,0.0015498885,0.00021541154,0.00030751893,0.0005009197,0.000026164918,0.00007821104,0.000043573214,0.06297177],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99810034,0.00008232674,0.0008769962,0.00053311617,0.0002462374,0.00016097864],"domain_scores_gemma":[0.9988272,0.00005641538,0.0005413437,0.0004083787,0.00009498132,0.000071640454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007359973,0.00019629956,0.00027774888,0.00004322485,0.00008956325,0.00003769937,0.0004257726,0.00033415467,0.000026230102],"category_scores_gemma":[0.00040421722,0.00015096698,0.00016250205,0.000050042454,0.00029221285,0.000011688948,0.0001276639,0.00027468597,0.000007853146],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001682533,0.000029246126,0.00007886302,0.000007132242,0.0000040255177,0.0000011122481,0.0000065504555,0.000014025128,0.98585904,0.0054735197,0.00010604388,0.00825217],"study_design_scores_gemma":[0.0005721824,0.00094027485,0.00023859931,0.0001754476,0.0000075197922,0.0000025879801,0.000017445383,0.0014706479,0.17258452,0.0028902136,0.82067436,0.00042617868],"about_ca_topic_score_codex":0.00000410443,"about_ca_topic_score_gemma":0.0000069515017,"teacher_disagreement_score":0.8205683,"about_ca_system_score_codex":0.000008361569,"about_ca_system_score_gemma":0.00024397015,"threshold_uncertainty_score":0.61562544},"labels":[],"label_agreement":null},{"id":"W1964310182","doi":"10.1016/j.bbrc.2005.12.016","title":"Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptor","year":2005,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Calnexin; Receptor; Mannosidase; G protein-coupled receptor; Cell surface receptor; Cell biology; 5-HT5A receptor; Cell; Glycan; Mannose; Biology; Cell membrane; Biochemistry; Chemistry; Glycoprotein; Calreticulin; Endoplasmic reticulum","score_opus":0.03759690873407839,"score_gpt":0.3461157625323881,"score_spread":0.30851885379830973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964310182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960168,0.0016692125,0.00004256771,0.0015003136,0.000008303198,0.0002499169,0.000052441108,0.0000020026007,0.0004584293],"genre_scores_gemma":[0.99855775,0.00052709976,0.0006850931,0.000057307654,0.000053662698,0.000024867226,0.000027176666,0.0000058984488,0.00006115124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984177,0.0006228052,0.00026500467,0.00015606481,0.00035803847,0.00018040086],"domain_scores_gemma":[0.9984801,0.00028537482,0.000081086626,0.0009370723,0.00016614245,0.000050245988],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091825565,0.000080093814,0.00013344748,0.00001606769,0.00013031985,0.000012830922,0.0009789967,0.000107284,0.000016515922],"category_scores_gemma":[0.00019413208,0.00004591186,0.000072217495,0.00016274906,0.00046119431,0.0000042665624,0.00041834475,0.00029047707,0.000002639982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006147827,0.00034030684,0.00015918253,0.000013353279,0.0000049622518,9.232302e-9,0.00013955889,0.0000039855377,0.99745107,0.0008987358,0.0003983283,0.00052904186],"study_design_scores_gemma":[0.00030531725,0.00007878428,0.0005076192,0.00002404495,0.0000038274793,2.5551287e-7,0.00057336036,0.00013273355,0.9937176,0.00027900937,0.0043201316,0.00005728425],"about_ca_topic_score_codex":0.00011710005,"about_ca_topic_score_gemma":0.000015100577,"teacher_disagreement_score":0.003921803,"about_ca_system_score_codex":0.000011619595,"about_ca_system_score_gemma":0.00005549394,"threshold_uncertainty_score":0.18722314},"labels":[],"label_agreement":null},{"id":"W1964332207","doi":"10.1016/j.cellimm.2010.03.006","title":"Fcγ receptors exhibit different phagocytosis potential in human neutrophils","year":2010,"lang":"en","type":"article","venue":"Cellular Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México; Universidad Nacional Autónoma de México; Consejo Nacional de Ciencia y Tecnología","keywords":"Phagocytosis; Biology; Receptor; Cell biology; Immunology; Microbiology; Biochemistry","score_opus":0.005054138749051951,"score_gpt":0.2120538546692069,"score_spread":0.20699971592015495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964332207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99564385,0.00074697915,0.0012832207,0.00010275014,0.0016891976,0.00018032725,0.0000035166463,0.000022420461,0.00032774036],"genre_scores_gemma":[0.9982554,0.00011987624,0.00022810661,0.00007135619,0.00039028746,0.00003255021,0.00017685437,0.00004194989,0.00068366644],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985199,0.00010784579,0.00033322175,0.0004899878,0.00009949634,0.0004495786],"domain_scores_gemma":[0.9992925,0.000006538657,0.00010067639,0.00049446005,0.000036690522,0.000069142254],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00015382897,0.00024558263,0.00026719965,0.000117429234,0.00012715401,0.000028938715,0.00035387866,0.00046320053,0.0009632737],"category_scores_gemma":[0.00002171596,0.00023549313,0.00015849617,0.000080986945,0.00012853257,0.0000047553885,0.00018972078,0.00042083242,0.00003422126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005156745,0.00011495668,0.00053469423,0.000005320983,0.000045526303,0.000014646309,0.000036142636,0.000014453297,0.99704504,0.00082727807,0.000097917175,0.0012124478],"study_design_scores_gemma":[0.0008387325,0.0002960037,0.0007850583,0.0000064070855,0.000013824775,0.000015373646,0.00005002536,0.00002331487,0.98856527,0.00043746835,0.00870601,0.0002625379],"about_ca_topic_score_codex":0.00005798005,"about_ca_topic_score_gemma":0.00006454534,"teacher_disagreement_score":0.008608093,"about_ca_system_score_codex":0.000016884931,"about_ca_system_score_gemma":0.000027218935,"threshold_uncertainty_score":0.99995},"labels":[],"label_agreement":null},{"id":"W1964401525","doi":"10.1016/s0305-0491(00)00199-1","title":"In vivo evidence for the production of sulfated steroids in the frog brain","year":2000,"lang":"en","type":"article","venue":"Comparative Biochemistry and Physiology Part B Biochemistry and Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Centre National de la Recherche Scientifique; Ministère de l'Enseignement Supérieur et de la Recherche; Ministère des Affaires Etrangères; Ministère de l'Education Nationale, de l'Enseignement Supérieur et de la Recherche; Institut National de la Santé et de la Recherche Médicale","keywords":"Diencephalon; Cerebrum; Hypothalamus; Internal medicine; Endocrinology; Biology; Central nervous system; In vivo; Preoptic area; Medicine","score_opus":0.03298748131016026,"score_gpt":0.320723302779842,"score_spread":0.28773582146968174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964401525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913666,0.0068665775,0.00017680254,0.0009722423,0.000087092114,0.00040167358,0.0000372337,0.00000405342,0.000087685854],"genre_scores_gemma":[0.9978575,0.0007114406,0.000118779404,0.0005303735,0.00019610568,0.00016822013,0.00009897904,0.0000091127995,0.00030950367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841785,0.0002156708,0.0003621489,0.0006444568,0.00005989477,0.0003000029],"domain_scores_gemma":[0.99912184,0.00024761487,0.00012457755,0.00039651137,0.00006418507,0.00004527394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050275866,0.0002617843,0.0003259614,0.00002169866,0.00011739298,0.0000134086895,0.00029455265,0.00031203433,0.0000627619],"category_scores_gemma":[0.00019079915,0.0001807045,0.000084555635,0.00014105997,0.0006198926,0.000007845513,0.00007039589,0.00018567297,4.7319713e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005704332,0.00007313592,0.00022389341,0.00007363067,0.0000503275,0.0000010343975,0.00019870728,0.00003955315,0.99736327,0.00008539601,0.0009871223,0.00033347018],"study_design_scores_gemma":[0.000523548,0.00026098383,0.00025521003,0.000064252185,0.000021380543,0.000026680473,0.0003584228,0.00009434367,0.9930715,0.00044243658,0.0046761907,0.00020503307],"about_ca_topic_score_codex":0.000016564816,"about_ca_topic_score_gemma":0.0000057963007,"teacher_disagreement_score":0.006490846,"about_ca_system_score_codex":0.000008789239,"about_ca_system_score_gemma":0.000051807616,"threshold_uncertainty_score":0.73689157},"labels":[],"label_agreement":null},{"id":"W1964497946","doi":"10.1038/sj.bjp.0706398","title":"Role of the PKC/CPI‐17 pathway in enhanced contractile responses of mesenteric arteries from diabetic rats to <i>α</i>‐adrenoceptor stimulation","year":2005,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Protein kinase C; Internal medicine; Mesenteric arteries; Endocrinology; Stimulation; Contraction (grammar); Circulatory system; Coronary arteries; Vasoconstriction; Receptor; Medicine; Chemistry; Phosphorylation; Artery; Biochemistry","score_opus":0.00669066635577419,"score_gpt":0.2554969867512623,"score_spread":0.2488063203954881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964497946","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99673504,0.0018944289,0.0005904405,0.00015086491,0.00035892255,0.00015346032,0.000058753292,0.0000012570667,0.000056851426],"genre_scores_gemma":[0.9984133,0.00020251803,0.0006717026,0.00026277688,0.0003220841,0.0000060085245,0.00000621144,0.000011780523,0.0001036095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882704,0.0002380016,0.00051434006,0.00013142952,0.00013174246,0.0001574365],"domain_scores_gemma":[0.99925005,0.00006266766,0.00039644048,0.000065667395,0.0001720879,0.000053079504],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025554554,0.000091161084,0.00027112782,0.00005640478,0.0000323646,0.00001089118,0.0002082905,0.00008954127,0.0008385064],"category_scores_gemma":[0.00008233303,0.00008807605,0.00011380715,0.000082435145,0.00005569177,0.000013589395,0.00005610756,0.00012540967,0.0000015600925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000567479,0.00013068394,0.00017234156,0.0000050657886,0.000049273163,0.0000046128034,0.00016146174,0.0013876797,0.9825121,0.0000011192383,0.00090760575,0.014100535],"study_design_scores_gemma":[0.0010617564,0.00031344153,0.0036036065,0.00006796677,0.000022215941,0.000038581424,0.0001278123,0.000049513474,0.9905362,0.00003800899,0.0040617557,0.00007914037],"about_ca_topic_score_codex":0.00003178743,"about_ca_topic_score_gemma":0.000053910127,"teacher_disagreement_score":0.014021395,"about_ca_system_score_codex":0.000018886132,"about_ca_system_score_gemma":0.00009879848,"threshold_uncertainty_score":0.9181057},"labels":[],"label_agreement":null},{"id":"W1964875492","doi":"10.1002/syn.20987","title":"Dopamine agonist radioligand binds to both D2High and D2Low receptors, explaining why alterations in D2High are not detected in human brain scans","year":2011,"lang":"en","type":"article","venue":"Synapse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Radioligand; Raclopride; Dopamine receptor D2; Dopamine; Agonist; Receptor; Internal medicine; Chemistry; Endocrinology; Dopamine receptor; Pharmacology; Biology; Biochemistry; Medicine","score_opus":0.018232438803946274,"score_gpt":0.24187189928143157,"score_spread":0.22363946047748529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964875492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976525,0.00016592204,0.0012941625,0.00021667547,0.00014814925,0.0002599448,0.00003047105,0.000015976919,0.00021621106],"genre_scores_gemma":[0.99755126,0.00003654743,0.0013719217,0.00040307984,0.00012974117,0.00006735433,0.00013034996,0.000033346878,0.000276379],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998618,0.00010917822,0.00033445592,0.00047982787,0.000100614285,0.00035793654],"domain_scores_gemma":[0.9994479,0.00001982517,0.00008551871,0.00026444154,0.000038399518,0.00014395434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002889666,0.00021625518,0.00024210216,0.00019191406,0.0001398303,0.000048104037,0.00015918279,0.00018622562,0.0001193251],"category_scores_gemma":[0.000105538486,0.00021892965,0.000041827585,0.00022622489,0.00005185258,0.000012255678,0.00009006301,0.00014915042,0.0000029379903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009955337,0.00006424404,0.0043456773,0.000012571332,0.000017457889,0.000023629858,0.0008671707,0.000041861553,0.9934196,0.00016652312,0.00048514068,0.00045658628],"study_design_scores_gemma":[0.0012088617,0.0005802501,0.008491996,0.00011643712,0.000009615222,0.000024605311,0.00058368547,0.00010015008,0.9858581,0.00009359905,0.0024931934,0.00043952256],"about_ca_topic_score_codex":0.00042619326,"about_ca_topic_score_gemma":0.0025427,"teacher_disagreement_score":0.0075614997,"about_ca_system_score_codex":0.00003157079,"about_ca_system_score_gemma":0.00003753644,"threshold_uncertainty_score":0.89276916},"labels":[],"label_agreement":null},{"id":"W1964939091","doi":"10.1016/j.yjmcc.2007.03.078","title":"Status of β-adrenoceptor signal transduction in heart failure due to volume overload in female rats","year":2007,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Heart failure; Internal medicine; Medicine; Endocrinology; Adenylyl cyclase; Volume overload; Stroke volume; Cardiac function curve; Cardiology; Cardioprotection; Hemodynamics; Adrenergic receptor; Downregulation and upregulation; Receptor; Biology; Myocardial infarction; Gene","score_opus":0.006381741824695387,"score_gpt":0.2238256546051972,"score_spread":0.21744391278050182,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964939091","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93976897,0.0031514901,0.056642942,0.00007566768,0.00017852082,0.0001227972,0.00000479719,0.0000012720758,0.000053522293],"genre_scores_gemma":[0.9970004,0.00009388928,0.0025952496,0.00008591611,0.00017856917,0.0000018088881,0.00001083508,0.000016519394,0.000016828853],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998537,0.00016921684,0.00054515275,0.0002223027,0.00016085082,0.00036545636],"domain_scores_gemma":[0.9994505,0.000012149062,0.00014023541,0.0001265262,0.000110667344,0.00015994474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008997393,0.00014738328,0.00047236876,0.0002347178,0.000018969924,0.000007868514,0.000098945,0.00023465797,0.000075945274],"category_scores_gemma":[0.000042266234,0.00014327162,0.00020079796,0.00015410538,0.000047576592,0.0000074053974,0.000032472544,0.00020861889,9.319002e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030864906,0.000031876883,0.0075073363,0.00001803773,0.000049107934,0.00021530654,0.00014095481,0.0018222837,0.9885864,0.000021855236,0.000094313116,0.0012038503],"study_design_scores_gemma":[0.00079881906,0.0009282281,0.0027528806,0.00003161575,0.00002151414,0.00028775568,0.0005267386,0.000010372274,0.9883006,0.00006744287,0.0061280457,0.00014597758],"about_ca_topic_score_codex":0.00003151517,"about_ca_topic_score_gemma":0.000034625176,"teacher_disagreement_score":0.057231393,"about_ca_system_score_codex":0.000029906214,"about_ca_system_score_gemma":0.00008656828,"threshold_uncertainty_score":0.5842447},"labels":[],"label_agreement":null},{"id":"W1965197125","doi":"10.1074/jbc.m208059200","title":"Insight into the Mechanism of Dopamine D1-like Receptor Activation","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Receptor; Adenylyl cyclase; Cell biology; Dopamine receptor; Dopaminergic; Dopamine receptor D2; Chemistry; G protein-coupled receptor; Potency; Biology; Dopamine; Biochemistry; In vitro; Endocrinology","score_opus":0.015239378069250895,"score_gpt":0.23509075719314068,"score_spread":0.2198513791238898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965197125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98817086,0.0005903227,0.010014354,0.00010417753,0.00017845682,0.000054464585,0.0000016902576,0.0000031342174,0.00088256004],"genre_scores_gemma":[0.9967449,0.0004565472,0.002107878,0.00012571548,0.00026572886,0.0000026673115,0.000012370887,0.000009280107,0.0002749271],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990372,0.00008455539,0.00041829285,0.00015356034,0.000164681,0.00014167985],"domain_scores_gemma":[0.9990809,0.000040098603,0.00042624073,0.00017461523,0.00020570964,0.000072453986],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050347403,0.00013460059,0.00021155375,0.000015250719,0.00006242745,0.000012167682,0.00024547838,0.0002507067,0.00036046712],"category_scores_gemma":[0.00039668844,0.000076538236,0.00017906725,0.00008762267,0.00007584671,0.0000050846243,0.000046602694,0.0001963437,0.0000014864488],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008177334,0.000061574756,0.00007692254,0.000012290567,0.00004628941,7.48635e-7,0.00004690753,0.000015815387,0.9982578,0.00021997957,0.00018853814,0.0009913233],"study_design_scores_gemma":[0.00030678557,0.0003056718,0.000015711366,0.000021226198,0.000009923144,0.000027578284,0.00019472558,0.000003916725,0.9520212,0.00061065383,0.046386775,0.00009582124],"about_ca_topic_score_codex":0.0000018465712,"about_ca_topic_score_gemma":1.5892685e-7,"teacher_disagreement_score":0.046236627,"about_ca_system_score_codex":0.000018415822,"about_ca_system_score_gemma":0.00006545859,"threshold_uncertainty_score":0.39468622},"labels":[],"label_agreement":null},{"id":"W1965789168","doi":"10.1021/bi036268v","title":"Role of the Rab11-Associated Intracellular Pool of Receptors Formed by Constitutive Endocytosis of the β Isoform of the Thromboxane A<sub>2</sub>Receptor (TPβ)","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Endocytosis; Gene isoform; Receptor; Intracellular; Cell biology; Thromboxane receptor; Thromboxane; Thromboxane A2; Chemistry; Biology; Biochemistry; Platelet; Immunology; Gene","score_opus":0.003423674614212373,"score_gpt":0.18246283340068534,"score_spread":0.17903915878647297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965789168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974516,0.0009903099,0.00009425835,0.00010100085,0.00025767603,0.00037238217,0.00033910997,0.0000055399005,0.00038810927],"genre_scores_gemma":[0.9994725,0.00016462491,0.00008833438,0.00003641183,0.000048911734,0.000016123591,0.000058896956,0.000023332354,0.00009087662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983463,0.000074245996,0.000604069,0.00029984835,0.00039126354,0.00028426797],"domain_scores_gemma":[0.99807876,0.00003280376,0.0008878108,0.0006856561,0.0002596882,0.000055258835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026355937,0.0002528539,0.0003834787,0.000015999487,0.00011494991,0.000006091962,0.0007626036,0.00036771086,0.000051976036],"category_scores_gemma":[0.00035888856,0.00015342206,0.00047464127,0.00028082504,0.0006870981,0.00000621718,0.00030316398,0.0001941858,6.603463e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056224162,0.00017974485,0.0005492695,0.00008204713,0.00020765448,4.347426e-8,0.00016114747,0.00004673499,0.99782676,0.00012978585,0.00037935292,0.0003812462],"study_design_scores_gemma":[0.0008126863,0.00010175534,0.00016236446,0.00020920813,0.00008142725,0.0000028725294,0.0005666591,0.000005946638,0.9973701,0.00027375028,0.00024896205,0.00016425815],"about_ca_topic_score_codex":0.00006490316,"about_ca_topic_score_gemma":0.000010038888,"teacher_disagreement_score":0.002020874,"about_ca_system_score_codex":0.00006867694,"about_ca_system_score_gemma":0.00040851106,"threshold_uncertainty_score":0.62563705},"labels":[],"label_agreement":null},{"id":"W1966074674","doi":"10.1016/j.cjca.2013.07.154","title":"Angiotensin II Induced Proteolytic Cleavage of Angiotensin Converting Enzyme 2 Is Mediated Via the Tnf-Alpha Converting Enzyme (TACE/ADAM-17): A Positive Feedback Mechanism in the Renin Angiotensin System","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton","funders":"","keywords":"Renin–angiotensin system; Angiotensin II; Medicine; Enzyme; Angiotensin-converting enzyme; Endocrinology; Angiotensin-converting enzyme 2; Internal medicine; Regulator; Cleavage (geology); Pharmacology; Biochemistry; Biology; Receptor; Disease","score_opus":0.010237039054581945,"score_gpt":0.20322366824280347,"score_spread":0.19298662918822151,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966074674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885795,0.0014868688,0.0035355769,0.004331206,0.00069571135,0.0009712277,0.000040067967,0.000008442588,0.0003514068],"genre_scores_gemma":[0.9970374,0.000020992948,0.00033731374,0.0016691621,0.0007917649,0.000015463384,0.00002729061,0.000051705447,0.000048906655],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99645555,0.00092851295,0.0010859744,0.00041166207,0.000307463,0.00081085897],"domain_scores_gemma":[0.99738663,0.00015464632,0.00082391535,0.0005083522,0.00077560614,0.00035082723],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018128888,0.00038587404,0.0008725695,0.00028327818,0.0003186148,0.00005514971,0.00065092294,0.0005739303,0.00002723102],"category_scores_gemma":[0.000398322,0.0002685453,0.00049015734,0.00036259898,0.0002320397,0.000028435777,0.00008920798,0.0006216052,0.00000991599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008191149,0.000006251078,0.00033706063,0.000011981557,0.0003893401,0.0001666146,0.0015339359,0.00012777129,0.9858712,0.00016921104,0.010338215,0.0009665169],"study_design_scores_gemma":[0.0017247217,0.0014037398,0.0045322613,0.00033268103,0.00021618028,0.0023407787,0.0029288966,0.0016283666,0.9809379,0.00029457413,0.0031033545,0.00055656664],"about_ca_topic_score_codex":0.0044669216,"about_ca_topic_score_gemma":0.00090615527,"teacher_disagreement_score":0.008457908,"about_ca_system_score_codex":0.00016465865,"about_ca_system_score_gemma":0.0007505144,"threshold_uncertainty_score":0.9999767},"labels":[],"label_agreement":null},{"id":"W1966169586","doi":"10.1016/j.mce.2003.11.019","title":"Expression of adenylyl cyclase-4 (AC-4) in Y1 and forskolin-resistant adrenal cells","year":2004,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Forskolin; Adenylyl cyclase; ADCY10; Mutant; Transfection; ADCY9; Biology; Molecular biology; Cyclase; Cell biology; Gene; Signal transduction; Cell culture; Endocrinology; Genetics; Stimulation","score_opus":0.005355998696588486,"score_gpt":0.2075253086793939,"score_spread":0.2021693099828054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966169586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9817658,0.005442979,0.01225271,0.0000519878,0.00008790839,0.00015955488,0.000009808336,0.0000075631315,0.00022166884],"genre_scores_gemma":[0.9972813,0.00040688625,0.002068146,0.000086686225,0.000035743346,0.000015057844,0.000036650374,0.00002370193,0.000045797893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987494,0.00007168623,0.00028892915,0.00042657717,0.000107581596,0.00035587026],"domain_scores_gemma":[0.9995512,0.000007968041,0.00008127654,0.00023434442,0.000032700358,0.000092521484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008932118,0.00019430193,0.00025849184,0.000099780824,0.000048431706,0.000012733583,0.00011871903,0.00016978937,0.000026382866],"category_scores_gemma":[0.00001812216,0.00018682386,0.00007491791,0.000063678046,0.00012083248,0.0000045868574,0.00016476496,0.00012951766,0.0000014874325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011174952,0.000057669462,0.000119165685,0.000037551963,0.000017848997,0.00012819636,0.000059870737,0.00018165412,0.9969563,0.0017653961,0.000009206406,0.0005553955],"study_design_scores_gemma":[0.0013929902,0.00038054047,0.0000741818,0.000038912633,0.000017112845,0.000046299025,0.00011876733,0.000018132116,0.9954098,0.0013657346,0.000945091,0.00019245157],"about_ca_topic_score_codex":0.00006414039,"about_ca_topic_score_gemma":0.000020817715,"teacher_disagreement_score":0.015515511,"about_ca_system_score_codex":0.000009674674,"about_ca_system_score_gemma":0.00003802522,"threshold_uncertainty_score":0.7618456},"labels":[],"label_agreement":null},{"id":"W1966248064","doi":"10.1196/annals.1387.055","title":"Topologic Investigation of the NCKX2 Na<sup>+</sup>/Ca<sup>2+</sup>‐K<sup>+</sup> Exchanger α‐Repeats","year":2007,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Radiochemistry; Isotopes of sodium; Chemistry; Physics; Sodium","score_opus":0.06394562756730258,"score_gpt":0.3098056574707196,"score_spread":0.245860029903417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966248064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98762184,0.0030041817,0.00024959305,0.0077785864,0.000121962716,0.0004066766,0.000028907,0.000014756259,0.00077349367],"genre_scores_gemma":[0.9934888,0.0004929469,0.0012069198,0.003163608,0.00044947895,0.000007835274,0.0000066864786,0.000020879497,0.0011628794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966553,0.00027333057,0.00083545386,0.00066677376,0.0009077325,0.00066140655],"domain_scores_gemma":[0.9984136,0.00013469637,0.0006829196,0.00041434256,0.00015376358,0.00020065061],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029401747,0.0003437896,0.00045243013,0.00014766314,0.00040845686,0.0000396126,0.0019048757,0.00049970194,0.0001702761],"category_scores_gemma":[0.00040230286,0.00021472522,0.00043011646,0.0008219559,0.0014829546,0.00004466668,0.00048403352,0.00033747105,0.000007297349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017149998,0.00010380389,0.005463909,0.00014080082,0.00017876131,7.062002e-7,0.0052894824,0.048769612,0.8998981,0.002933189,0.028519051,0.008531087],"study_design_scores_gemma":[0.00029869375,0.0003631642,0.00082542305,0.00018605302,0.000042177864,0.000009972571,0.0023297782,0.0032014695,0.97735924,0.007267966,0.007835672,0.00028036645],"about_ca_topic_score_codex":0.00022795645,"about_ca_topic_score_gemma":0.000004190792,"teacher_disagreement_score":0.07746117,"about_ca_system_score_codex":0.000013708056,"about_ca_system_score_gemma":0.00020000299,"threshold_uncertainty_score":0.87562406},"labels":[],"label_agreement":null},{"id":"W1966415698","doi":"10.1096/fj.07-9002com","title":"Glucocorticoids regulate innate immunity in a model of multiple sclerosis: reciprocal interactions between the A1 adenosine receptor and β‐arrestin‐1 in monocytoid cells","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials; University of Alberta; University of Calgary","funders":"","keywords":"Neuroinflammation; Experimental autoimmune encephalomyelitis; Proinflammatory cytokine; Cell biology; Biology; Arrestin; Receptor; Neuroscience; Endocrinology; Internal medicine; G protein-coupled receptor; Chemistry; Immunology; Central nervous system; Inflammation; Signal transduction; Medicine","score_opus":0.038190046638098586,"score_gpt":0.2571014013726095,"score_spread":0.21891135473451093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966415698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920034,0.0005667623,0.006926703,0.00017617636,0.00011860235,0.00016198309,0.0000112410335,0.000003041965,0.00003208952],"genre_scores_gemma":[0.9979599,0.00055225205,0.0012122928,0.000053356347,0.00014603409,0.0000054122947,0.00000765103,0.000015749762,0.000047311023],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987814,0.00016644548,0.0004860494,0.0001454684,0.00013144643,0.000289214],"domain_scores_gemma":[0.99933934,0.000089364716,0.00021032104,0.0002183884,0.0000633412,0.00007923185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013970435,0.0001310319,0.0001752695,0.00008815588,0.00015992083,0.000033044234,0.00025494248,0.00009368373,0.000014852059],"category_scores_gemma":[0.00012135563,0.00008455436,0.000067984445,0.00015548673,0.0001079719,0.000012913465,0.0001234629,0.000495506,9.724081e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023333191,0.000042833126,0.0048527103,0.0000048829643,0.000024139263,0.0000012348086,0.00045478984,0.0037102338,0.98593265,0.000006631397,0.00003204724,0.0047044954],"study_design_scores_gemma":[0.0007927426,0.00011710174,0.009151359,0.00011311216,0.000015771653,0.000017874803,0.00058748026,0.005226698,0.98357004,0.00025280128,0.000049020768,0.00010601171],"about_ca_topic_score_codex":0.00010620671,"about_ca_topic_score_gemma":0.00015341202,"teacher_disagreement_score":0.00595654,"about_ca_system_score_codex":0.000038468155,"about_ca_system_score_gemma":0.000059963906,"threshold_uncertainty_score":0.34480268},"labels":[],"label_agreement":null},{"id":"W1967120431","doi":"10.1038/sj.npp.1301145","title":"Role of α1-Adrenoceptors of the Locus Coeruleus in Self-Stimulation of the Medial Forebrain Bundle","year":2006,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Institute of Mental Health; York University","keywords":"Locus coeruleus; Medial forebrain bundle; Agonist; Stimulation; Phenylephrine; Endocrinology; Prazosin; Alpha (finance); Internal medicine; Chemistry; Forebrain; Receptor; Psychology; Neuroscience; Dopamine; Central nervous system; Biology; Dopaminergic; Medicine; Antagonist; Developmental psychology","score_opus":0.0030058265007107754,"score_gpt":0.21969366109978722,"score_spread":0.21668783459907645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967120431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980291,0.00022987604,0.000035402125,0.00007534804,0.0007118924,0.000276267,0.000016222999,0.000003924493,0.00062196306],"genre_scores_gemma":[0.99951714,0.000024889167,0.000109377936,0.00010598606,0.00015661621,0.000009196393,0.0000064333885,0.000016053462,0.000054279284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989007,0.00020926497,0.00037767895,0.00019451148,0.00015772604,0.00016010807],"domain_scores_gemma":[0.99935555,0.000034633413,0.0002780838,0.00022695692,0.00008491446,0.000019834715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017159763,0.00010970478,0.00017343655,0.000042041684,0.000031503205,0.0000019433062,0.00032105445,0.00013885976,0.00010966739],"category_scores_gemma":[0.00003278053,0.00007558922,0.00012788367,0.0001970072,0.00011697804,0.0000027813496,0.00009452892,0.00012237871,6.5163266e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012691272,0.00018100436,0.010000211,0.000014418268,0.000013864242,1.865172e-7,0.000060907387,0.0024994127,0.9863023,0.00017680723,0.00034359505,0.0002803433],"study_design_scores_gemma":[0.0011730485,0.00022257399,0.020718599,0.0000071493128,0.000025664072,0.0000028664958,0.000019221567,0.00041536722,0.9756767,0.000496194,0.0011759729,0.00006660289],"about_ca_topic_score_codex":0.00006613722,"about_ca_topic_score_gemma":0.000037837734,"teacher_disagreement_score":0.010718388,"about_ca_system_score_codex":0.000008525849,"about_ca_system_score_gemma":0.00006239103,"threshold_uncertainty_score":0.3082439},"labels":[],"label_agreement":null},{"id":"W1967942269","doi":"10.1159/000233209","title":"Regulation of the Murine IgE Antibody Response","year":2009,"lang":"en","type":"article","venue":"International Archives of Allergy and Applied Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Immunoglobulin E; Antigen; Immunology; Spleen; Antibody; Adjuvant; Population; Biology; Medicine","score_opus":0.00392124132818657,"score_gpt":0.2235169112099862,"score_spread":0.21959566988179963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1967942269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99310595,0.00016957324,0.0027603868,0.00039407925,0.00009326807,0.000052365038,0.0000052181463,0.0000023780633,0.003416793],"genre_scores_gemma":[0.99865764,0.00020653143,0.0007002681,0.00005899255,0.000036409718,0.0000018072836,0.00003178833,0.000003455229,0.00030308892],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99957806,0.00003274309,0.00015318852,0.00011530768,0.00005691017,0.00006379469],"domain_scores_gemma":[0.9997211,0.000022829587,0.0001026368,0.00012493967,0.000019338779,0.0000091287975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006203696,0.000059271468,0.000078144774,0.000037201324,0.000030107123,0.0000025486172,0.00017143061,0.00004478353,0.000034127657],"category_scores_gemma":[0.000020290085,0.000045582823,0.000045195047,0.000020851212,0.000109287656,0.0000016004271,0.00007743143,0.00004258636,2.901215e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011957197,0.00003706315,0.000030973777,9.453614e-7,0.00009746737,7.900831e-8,0.00007243626,0.00013905593,0.96964806,0.020520382,0.000008496395,0.008249334],"study_design_scores_gemma":[0.00036403842,0.00016222821,0.107437216,0.000010816344,0.000002101185,0.0000054642046,0.000034316567,0.00007227072,0.8810786,0.0064134733,0.0043735825,0.0000459188],"about_ca_topic_score_codex":0.000003948053,"about_ca_topic_score_gemma":0.0000014430275,"teacher_disagreement_score":0.10740624,"about_ca_system_score_codex":0.0000013898083,"about_ca_system_score_gemma":0.0000145122385,"threshold_uncertainty_score":0.18588136},"labels":[],"label_agreement":null},{"id":"W1968124846","doi":"10.1016/j.pnpbp.2012.10.015","title":"Potential translational targets revealed by linking mouse grooming behavioral phenotypes to gene expression using public databases","year":2012,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute on Alcohol Abuse and Alcoholism; Tulane University","keywords":"Phenotype; Expression (computer science); Gene expression; Gene; Psychology; Database; Biology; Genetics; Computer science","score_opus":0.03792744729791131,"score_gpt":0.3349104782822987,"score_spread":0.2969830309843874,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968124846","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98247856,0.010313761,0.0047571547,0.0003860457,0.0015533823,0.00039593058,0.00007652689,0.00002959537,0.000009063159],"genre_scores_gemma":[0.973711,0.00030760866,0.023625059,0.0011279283,0.00085853785,0.0000654809,0.0002702649,0.00002593529,0.000008166988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980076,0.00026334316,0.00037919203,0.00061548065,0.00013005025,0.00060431147],"domain_scores_gemma":[0.9994056,0.000023054537,0.00011907088,0.00015440914,0.000038442737,0.00025942686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036967773,0.0002766967,0.00024645508,0.000098363314,0.00022715352,0.000030462666,0.00021921135,0.00028410423,0.00012557948],"category_scores_gemma":[0.000016956164,0.0002317197,0.00008287538,0.00013614797,0.00012804111,0.000031064323,0.00014992636,0.0002865392,0.0000026015218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004471263,0.00039395594,0.4225062,0.000010777653,0.000013638777,0.0000021361936,0.000019807212,0.000011532456,0.57466453,0.00003476515,0.00030945454,0.0015860607],"study_design_scores_gemma":[0.017904362,0.0037521408,0.34926143,0.00022525694,0.00030092176,0.00040247885,0.00034419313,0.0010946996,0.5870759,0.0008575999,0.03460076,0.0041802446],"about_ca_topic_score_codex":0.000002171083,"about_ca_topic_score_gemma":0.0000018146452,"teacher_disagreement_score":0.07324476,"about_ca_system_score_codex":0.00000790826,"about_ca_system_score_gemma":0.000029617158,"threshold_uncertainty_score":0.94492555},"labels":[],"label_agreement":null},{"id":"W1968136709","doi":"10.1016/j.bpj.2013.11.631","title":"Nature of the M2 Muscarinic Receptor Signaling Complex Revealed by Dual-Color FCS and FRET","year":2014,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Förster resonance energy transfer; G protein-coupled receptor; Biophysics; Receptor; Chemistry; G protein; Green fluorescent protein; Cell biology; Biochemistry; Fluorescence; Biology","score_opus":0.00695449873991924,"score_gpt":0.22920267181226406,"score_spread":0.22224817307234482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968136709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981127,0.00015314463,0.00089764234,0.0003338643,0.0002937313,0.00008321162,0.000021316662,0.0000042004076,0.000100222176],"genre_scores_gemma":[0.9976213,0.000065640146,0.0009826085,0.00038474178,0.00076246157,0.0000022096726,0.000017169641,0.000017889564,0.00014597984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989882,0.00015311965,0.00024935717,0.00020730909,0.00020343938,0.00019856532],"domain_scores_gemma":[0.9993807,0.000030218216,0.00019812796,0.00018620481,0.00009437665,0.000110390996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026980613,0.00014350451,0.00020479287,0.000016393335,0.0001661429,0.00003981582,0.00020063165,0.00020891622,0.00008076186],"category_scores_gemma":[0.00007838208,0.00009532973,0.00016568271,0.00007108783,0.000100411635,0.0000046900946,0.00011338985,0.0003549017,0.000002572195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041290303,0.000040945368,0.00017151517,0.000011502214,0.00004095399,3.4419668e-7,0.000022547516,0.000009601879,0.99360824,0.00026514838,0.0050016697,0.00078625267],"study_design_scores_gemma":[0.00051787554,0.00034588744,0.0007796952,0.000033812234,0.000029956464,0.000029922208,0.00004143079,0.00025487022,0.9794594,0.00026993736,0.01807929,0.0001579245],"about_ca_topic_score_codex":0.000002704297,"about_ca_topic_score_gemma":6.994441e-7,"teacher_disagreement_score":0.01414883,"about_ca_system_score_codex":0.000008653527,"about_ca_system_score_gemma":0.000027560784,"threshold_uncertainty_score":0.38874334},"labels":[],"label_agreement":null},{"id":"W1968231599","doi":"10.1016/j.neuroscience.2005.12.030","title":"Developmental pattern of M1 and M2 muscarinic gene expression and receptor levels in cat carotid body, petrosal and superior cervical ganglion","year":2006,"lang":"en","type":"article","venue":"Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec; Hôpital Saint-François d'Assise; Université Laval","funders":"","keywords":"Superior cervical ganglion; Endocrinology; Internal medicine; CATS; Tyrosine hydroxylase; Muscarinic acetylcholine receptor; Biology; Ganglion; Carotid body; Receptor; Medicine; Dopamine; Anatomy; Stimulation","score_opus":0.010770791269776467,"score_gpt":0.2233715285785112,"score_spread":0.21260073730873474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968231599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991533,0.00012908863,0.00048078538,0.000022268001,0.00009015471,0.000088405126,0.000014108258,0.0000035020232,0.000018373607],"genre_scores_gemma":[0.99862313,0.00009312417,0.0011184531,0.000068980116,0.000036583606,0.000005494735,0.000005942674,0.000008138263,0.00004012122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991785,0.000034108212,0.0001538748,0.00036150863,0.000112257294,0.00015969778],"domain_scores_gemma":[0.999816,0.00000771236,0.000038821003,0.00006556647,0.000016243164,0.000055630317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010895989,0.00009954658,0.00010771242,0.00003942412,0.00006174752,0.00002650043,0.000074285235,0.0000677896,0.000009549556],"category_scores_gemma":[0.000022412327,0.000089816866,0.000013608036,0.000060447088,0.00011608742,0.000010108413,0.00016357645,0.00004485053,1.9355979e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000073575857,0.000016036916,0.08889178,0.000011136924,2.8725532e-7,0.0000016732428,0.0000535052,0.0000028694171,0.9105639,0.0000032125663,0.00000949393,0.00043877994],"study_design_scores_gemma":[0.00026434168,0.000111907466,0.2080559,0.000013922034,0.0000013038334,0.000029480556,0.000041077554,0.00009386641,0.7911938,0.000007181335,0.000103313425,0.000083925515],"about_ca_topic_score_codex":0.000084422434,"about_ca_topic_score_gemma":0.00003293623,"teacher_disagreement_score":0.11937008,"about_ca_system_score_codex":0.000006451962,"about_ca_system_score_gemma":0.00002911588,"threshold_uncertainty_score":0.36626256},"labels":[],"label_agreement":null},{"id":"W1968242163","doi":"10.1016/j.tips.2011.02.001","title":"The major impacts of James Black's drug discoveries on medicine and pharmacology","year":2011,"lang":"en","type":"article","venue":"Trends in Pharmacological Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Innovator; Medicine; Pharmacology; Drug; Drug discovery; Clinical pharmacology; Engineering ethics; Engineering; Bioinformatics; Political science; Law; Biology","score_opus":0.04850701833864808,"score_gpt":0.34730902937318203,"score_spread":0.29880201103453397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968242163","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912963,0.0011734782,0.000010118126,0.0008887268,0.0002783389,0.00006676174,0.0000034205723,0.0000050183467,0.0062778476],"genre_scores_gemma":[0.99804246,0.0010386751,0.0001210058,0.00044320704,0.00010230026,0.000010767563,0.0000017822703,0.0000031246925,0.00023664635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904275,0.00011958842,0.00019460506,0.00025657608,0.0001373668,0.00024913487],"domain_scores_gemma":[0.9996796,0.000089506946,0.00008834293,0.00005660646,0.000016991055,0.000068908],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006566032,0.00011100211,0.00014013152,0.00006043702,0.00015260224,0.000009477123,0.00027951383,0.00004987105,0.0010091651],"category_scores_gemma":[0.000041969855,0.000054958746,0.00003445266,0.00020543823,0.0014682214,0.000006833255,0.000102947226,0.00008455401,0.0000010891348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027334003,0.00008659038,0.0019940406,0.000004463243,0.00002839415,0.0000043269542,0.0006187515,0.000012250461,0.9819492,0.0016401911,0.0051575517,0.008230877],"study_design_scores_gemma":[0.0006791063,0.0013577036,0.0034860033,0.000010579263,0.000025317735,0.0000026783537,0.00087451335,0.00008312875,0.98920023,0.0012462027,0.0029236148,0.00011089498],"about_ca_topic_score_codex":0.000067837005,"about_ca_topic_score_gemma":0.00003144082,"teacher_disagreement_score":0.008119983,"about_ca_system_score_codex":0.0000056565837,"about_ca_system_score_gemma":0.000017317321,"threshold_uncertainty_score":0.99990404},"labels":[],"label_agreement":null},{"id":"W1968312985","doi":"10.1021/bi991938b","title":"Role for the C-Terminus in Agonist-Induced μ Opioid Receptor Phosphorylation and Desensitization","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse","keywords":"DAMGO; Enzyme-linked receptor; Homologous desensitization; Receptor; 5-HT5A receptor; Opioid receptor; Chemistry; Interleukin-21 receptor; Protease-activated receptor 2; Estrogen-related receptor alpha; Phosphorylation; Agonist; Biology; Cell biology; Molecular biology; Biochemistry; Estrogen receptor","score_opus":0.007412767501125018,"score_gpt":0.22565275982268573,"score_spread":0.21823999232156072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968312985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99806863,0.0008155918,0.00040223636,0.00007573598,0.000049223945,0.00027909837,0.000013654777,0.000008325627,0.0002875241],"genre_scores_gemma":[0.997588,0.0002037334,0.0006237579,0.00009555077,0.00024260722,0.00008003981,0.00017834394,0.000016345844,0.0009716607],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993872,0.0000124979215,0.00013721913,0.00025020077,0.000062310246,0.0001505564],"domain_scores_gemma":[0.99970233,0.00001731717,0.00003770222,0.00017018979,0.000034043358,0.000038423594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012821167,0.00010662319,0.00007647422,0.000009536577,0.00009599936,0.000033848326,0.000080880236,0.00015077849,0.000103955615],"category_scores_gemma":[0.000035128556,0.000090915026,0.00004012768,0.000047363254,0.000025662705,0.00000304829,0.000018945764,0.000049132897,0.0000031888326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072940755,0.000014379486,0.00008904447,0.000012685656,0.000007895438,2.8847336e-7,0.00004228754,0.00002255982,0.9653259,0.000009062109,0.00023653527,0.034166437],"study_design_scores_gemma":[0.00034745582,0.00005023211,0.0002131497,0.000015478885,0.00000616473,0.000006873199,0.000104956336,0.0010098576,0.98964924,0.00006228997,0.008410785,0.00012352013],"about_ca_topic_score_codex":0.000018036753,"about_ca_topic_score_gemma":0.0000057204493,"teacher_disagreement_score":0.034042917,"about_ca_system_score_codex":0.000014383343,"about_ca_system_score_gemma":0.000038214017,"threshold_uncertainty_score":0.3707407},"labels":[],"label_agreement":null},{"id":"W1968517606","doi":"10.1016/j.yjmcc.2007.11.019","title":"RGS5, RGS4, and RGS2 expression and aortic contractibility are dynamically co-regulated during aortic banding-induced hypertrophy","year":2008,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; American Heart Association","keywords":"RGS2; Cardiology; Internal medicine; Muscle hypertrophy; Medicine; G protein; Receptor; GTPase-activating protein","score_opus":0.007922806326325662,"score_gpt":0.21496581145479268,"score_spread":0.20704300512846702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968517606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905986,0.0044775438,0.0045446777,0.00005397606,0.00014516851,0.00013221231,0.0000043554674,0.000006207466,0.0000372193],"genre_scores_gemma":[0.9985124,0.0008733975,0.00032978057,0.00006515446,0.00015830269,0.000002795678,0.000011162646,0.000026452035,0.000020546171],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984301,0.00025868422,0.00046708641,0.00037750424,0.00017802854,0.00028859565],"domain_scores_gemma":[0.99907964,0.00002457831,0.00031138433,0.00021641806,0.00013839513,0.00022955723],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033456337,0.0002351163,0.0005668242,0.00008527216,0.00018619237,0.000026172496,0.000098866,0.00030931813,0.000008400748],"category_scores_gemma":[0.000117758136,0.00019750847,0.00018115842,0.000047014215,0.00016586055,0.000013946844,0.000089003675,0.0002650704,4.4121415e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026008592,0.00002453393,0.009949591,0.000033896857,0.00016070991,0.00041142481,0.00004430471,0.000046133722,0.98873925,0.0000063313864,0.000012464,0.00031127635],"study_design_scores_gemma":[0.0016867364,0.0006208879,0.018558359,0.00004869901,0.0001093969,0.0027355435,0.0001021512,0.00014607588,0.9755187,0.000094202165,0.00012097165,0.0002582619],"about_ca_topic_score_codex":0.0000050083286,"about_ca_topic_score_gemma":5.935053e-7,"teacher_disagreement_score":0.013220534,"about_ca_system_score_codex":0.000018560806,"about_ca_system_score_gemma":0.00004505128,"threshold_uncertainty_score":0.8054162},"labels":[],"label_agreement":null},{"id":"W1968584652","doi":"10.1210/en.2007-0313","title":"Angiotensin II Type 2 Receptor Stimulation Increases the Rate of NG108–15 Cell Migration via Actin Depolymerization","year":2008,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Colorado State University","keywords":"Internal medicine; Endocrinology; Pertussis toxin; Angiotensin II; Receptor; Cofilin; Chelerythrine; Biology; Cell biology; Chemistry; Actin cytoskeleton; Signal transduction; G protein; Cell; Cytoskeleton; Biochemistry; Protein kinase C; Medicine","score_opus":0.012042546053108292,"score_gpt":0.22431507287291047,"score_spread":0.2122725268198022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968584652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99161124,0.0007575513,0.006945262,0.00015965405,0.00024705133,0.00013733692,0.0000048923803,0.000014038235,0.00012295801],"genre_scores_gemma":[0.99770015,0.00047490286,0.000944998,0.00014438007,0.00018897826,0.000006621437,0.00023342921,0.000015627778,0.00029090478],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992198,0.00014032377,0.00020100354,0.0002006008,0.00006180463,0.00017652044],"domain_scores_gemma":[0.99952304,0.00002716157,0.00014347212,0.0002057027,0.000072547984,0.000028057366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005113992,0.00010977564,0.000121859564,0.000040584375,0.00017372773,0.000003998983,0.00009844062,0.00009756426,0.00011441551],"category_scores_gemma":[0.000061347164,0.00008855977,0.000056044497,0.000105948304,0.00007082228,0.0000058228284,0.000059634636,0.00006313479,0.000008026601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010214283,0.000047414338,0.001237208,0.0000034915927,0.000018736971,0.0000015171842,0.00008819075,0.00048488675,0.9963722,0.00005273405,0.0006775797,0.0009139024],"study_design_scores_gemma":[0.00028937386,0.0003787109,0.0012355224,0.0000030039557,0.000014398826,0.000029128387,0.000039982497,0.00038003133,0.9923048,0.000031770895,0.0051983115,0.000094991155],"about_ca_topic_score_codex":0.00023815803,"about_ca_topic_score_gemma":0.000028774992,"teacher_disagreement_score":0.0060889022,"about_ca_system_score_codex":0.0000053908097,"about_ca_system_score_gemma":0.00004446174,"threshold_uncertainty_score":0.36113626},"labels":[],"label_agreement":null},{"id":"W1969077273","doi":"10.1021/bi048328i","title":"Light-Driven Activation of β<sub>2</sub>-Adrenergic Receptor Signaling by a Chimeric Rhodopsin Containing the β<sub>2</sub>-Adrenergic Receptor Cytoplasmic Loops","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":167,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; National Institute of General Medical Sciences; University of British Columbia; University of Texas Southwestern Medical Center","keywords":"Rhodopsin; Transducin; Transmembrane domain; G protein-coupled receptor; Receptor; Biophysics; Cytoplasm; Signal transduction; Transmembrane protein; Chemistry; Biology; Cell biology; Biochemistry; Retinal","score_opus":0.006974240511496936,"score_gpt":0.20945569853731882,"score_spread":0.20248145802582188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969077273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99644923,0.0016745628,0.0006774586,0.0002583355,0.00024188653,0.00033213125,0.000057779576,0.000050742976,0.00025786782],"genre_scores_gemma":[0.99641675,0.00069720804,0.0008519127,0.00024520737,0.00087729463,0.00010449984,0.0006151608,0.000107378466,0.000084579464],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967564,0.00017331714,0.0008981589,0.000980056,0.00046199845,0.0007300671],"domain_scores_gemma":[0.998205,0.00007967369,0.000607948,0.00070205453,0.00019713101,0.00020816214],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005253902,0.000598066,0.0005548574,0.00010646091,0.00023131598,0.00007319975,0.00061114744,0.0006295252,0.0000918461],"category_scores_gemma":[0.00016698168,0.00054305047,0.00032439435,0.00045474432,0.00012795228,0.000029405213,0.00019129497,0.0004278361,0.000027958185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039474547,0.00016387476,0.0001717496,0.00006436057,0.000116610616,0.0000015587582,0.00013510276,0.0014413809,0.989033,0.00001727722,0.0016666438,0.0067936867],"study_design_scores_gemma":[0.0011306938,0.00030754315,0.000023520819,0.0002064119,0.00004065184,0.000016226768,0.0003925269,0.00053884316,0.9939893,0.000017527205,0.002694137,0.00064261723],"about_ca_topic_score_codex":0.000021424057,"about_ca_topic_score_gemma":0.000009645327,"teacher_disagreement_score":0.006151069,"about_ca_system_score_codex":0.00016723777,"about_ca_system_score_gemma":0.00025812772,"threshold_uncertainty_score":0.9997021},"labels":[],"label_agreement":null},{"id":"W1969179176","doi":"10.1038/mp.2013.115","title":"Antidepressant-like and anxiolytic-like effects following activation of the μ-δ opioid receptor heteromer in the nucleus accumbens","year":2013,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Nucleus accumbens; Anxiolytic; Pharmacology; Agonist; Chemistry; Antidepressant; Neuroscience; Tail suspension test; Elevated plus maze; Behavioural despair test; Receptor; Medicine; Biology; Biochemistry; Psychiatry; Anxiety","score_opus":0.004041097061723545,"score_gpt":0.214794058114249,"score_spread":0.21075296105252547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969179176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958622,0.0007766221,0.0015448737,0.00026616515,0.0008261342,0.0005407227,0.000003468359,0.000006360129,0.00017348918],"genre_scores_gemma":[0.9970714,0.000045642566,0.0014152203,0.0012625606,0.00007623131,0.000050411007,0.000016507456,0.000027205502,0.000034816505],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988555,0.00017277252,0.00022600255,0.0003129581,0.00020108769,0.00023168384],"domain_scores_gemma":[0.99933374,0.000020424292,0.00010834787,0.00046866506,0.000029521054,0.000039275576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019137003,0.00017516689,0.00015995446,0.00003738463,0.000094199604,0.000049649956,0.0003102729,0.00013122305,0.000021194026],"category_scores_gemma":[0.000036153793,0.00011539101,0.00016722758,0.00014156969,0.000044647084,0.000011688589,0.00011185411,0.00014709357,0.0000043113873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014813614,0.000054409982,0.012093591,0.000039598242,0.00004913174,6.606633e-7,0.000112009315,0.000027052018,0.9856019,0.00012549658,0.00091685855,0.0009644598],"study_design_scores_gemma":[0.0012041256,0.00029071895,0.03179045,0.00019121081,0.00005238515,0.000012478329,0.00043651892,0.00015501259,0.9609793,0.0010739085,0.0034547946,0.00035912977],"about_ca_topic_score_codex":0.0000673738,"about_ca_topic_score_gemma":0.000010276598,"teacher_disagreement_score":0.024622655,"about_ca_system_score_codex":0.000006470718,"about_ca_system_score_gemma":0.000034172088,"threshold_uncertainty_score":0.4705509},"labels":[],"label_agreement":null},{"id":"W1969239442","doi":"10.1023/b:mcbi.0000038236.59905.8b","title":"AT2 receptor and apoptosis during AT1 receptor blockade in reperfused myocardial infarction in the rat","year":2004,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Candesartan; Internal medicine; Angiotensin II; Ejection fraction; Downregulation and upregulation; Medicine; TUNEL assay; Apoptosis; In vivo; Blockade; Angiotensin receptor; Endocrinology; Cardiology; Infarction; Myocardial infarction; Ex vivo; Receptor; Chemistry; Biology; Heart failure; Immunohistochemistry; Biochemistry","score_opus":0.0037100642671866304,"score_gpt":0.19076808510538013,"score_spread":0.1870580208381935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969239442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963648,0.0023852498,0.0003556516,0.00037504002,0.00011082703,0.00023702907,0.0000072059047,0.00001164566,0.00015256756],"genre_scores_gemma":[0.99858975,0.0002822656,0.00047125673,0.00020473091,0.00016957209,0.000052170763,0.00014145907,0.00003179411,0.000056984823],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983905,0.000100144374,0.00030525003,0.00060790253,0.00020257625,0.0003936156],"domain_scores_gemma":[0.9994151,0.000007230913,0.00007395257,0.00036515557,0.000030512872,0.00010806955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037090885,0.00026978718,0.00021310747,0.00006181175,0.00010984772,0.00007002916,0.00017953038,0.000329788,0.000021246748],"category_scores_gemma":[0.000065620516,0.000244976,0.00012180757,0.0001845819,0.00009408606,0.0000076157817,0.00011703797,0.0002563156,0.0000025038435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008748343,0.000057760008,0.0005339892,0.00005235961,0.000028064105,0.00001034847,0.0001386426,0.00006390706,0.99872243,0.000035663255,0.000017203543,0.0002521429],"study_design_scores_gemma":[0.0014414041,0.00008617317,0.0000932218,0.00005959669,0.000016852027,0.000025606432,0.00050569465,0.000004668809,0.99681115,0.00009377988,0.00055724767,0.0003045738],"about_ca_topic_score_codex":0.0000753299,"about_ca_topic_score_gemma":0.000005666036,"teacher_disagreement_score":0.0022249827,"about_ca_system_score_codex":0.000046103098,"about_ca_system_score_gemma":0.000053402837,"threshold_uncertainty_score":0.9989831},"labels":[],"label_agreement":null},{"id":"W1969487465","doi":"10.1016/j.pbb.2006.04.011","title":"Effects of central neurokinin-1 receptor antagonism on cocaine- and opiate-induced locomotor activity and self-administration behaviour in rats","year":2006,"lang":"en","type":"article","venue":"Pharmacology Biochemistry and Behavior","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Self-administration; Tachykinin receptor 1; Opiate; Locomotor activity; Pharmacology; Neuropeptide; Morphine; Addiction; Antagonist; Psychology; Receptor; Substance P; Internal medicine; Medicine; Neuroscience","score_opus":0.006056595901422759,"score_gpt":0.2627024900465151,"score_spread":0.2566458941450923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969487465","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998991,0.0002485982,0.00000880824,0.000062484476,0.00023067827,0.00039735727,0.00003350143,0.0000138023,0.000013782551],"genre_scores_gemma":[0.9991799,0.00023692928,0.0001258653,0.00005628653,0.00018574328,0.00008045412,0.00006415795,0.000017346667,0.000053332573],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988787,0.0000814702,0.00021969026,0.00046594974,0.00008465749,0.0002695134],"domain_scores_gemma":[0.999609,0.000033571843,0.00012221232,0.000093868315,0.00003184219,0.000109519],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011044818,0.00022763132,0.00022901563,0.000039018476,0.000076536984,0.000019854744,0.00007073345,0.0002755658,0.000012800449],"category_scores_gemma":[0.000010372701,0.0002325963,0.000038402053,0.000050761835,0.0000907627,0.000008855431,0.000065931075,0.00017566215,2.6381687e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026308745,0.00077960105,0.008945774,0.0001139743,0.00001430709,0.000028142771,0.000019905137,5.6716294e-7,0.9891295,0.0000064431397,0.00004858608,0.0006501566],"study_design_scores_gemma":[0.0015089524,0.0006997426,0.043173596,0.000016193357,0.000115429655,0.0000311469,0.000014025105,0.00001723208,0.9541676,0.0000041249514,0.000043890184,0.00020805966],"about_ca_topic_score_codex":0.000037435086,"about_ca_topic_score_gemma":0.000004447628,"teacher_disagreement_score":0.034961846,"about_ca_system_score_codex":0.00001606119,"about_ca_system_score_gemma":0.00005512572,"threshold_uncertainty_score":0.9485002},"labels":[],"label_agreement":null},{"id":"W1969556083","doi":"10.1021/jm300215x","title":"Discovery of a Potent and Selective GPR120 Agonist","year":2012,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":162,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"GPR120; Free fatty acid receptor 1; Chemistry; Agonist; Receptor; Pharmacology; Diabetes mellitus; Biochemistry; G protein-coupled receptor; Endocrinology; Medicine","score_opus":0.006733846896537571,"score_gpt":0.2358746493533729,"score_spread":0.22914080245683532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969556083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918156,0.005145803,0.0018218494,0.00007690965,0.00014410878,0.000025562535,0.0000035231772,9.420091e-7,0.00096569874],"genre_scores_gemma":[0.9979482,0.00036046148,0.00049645995,0.00005225947,0.00091654866,6.644333e-7,0.0000041544577,0.000008932493,0.0002123003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992641,0.000018512128,0.00027942384,0.00007959923,0.00020595179,0.00015239224],"domain_scores_gemma":[0.99938065,0.000013703754,0.00028976076,0.00008186328,0.000118026976,0.00011597572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037859305,0.00009545446,0.00019449586,0.0000162694,0.000027739037,0.000007804248,0.000091437934,0.000096040145,0.00001668513],"category_scores_gemma":[0.00011330555,0.0000725136,0.00008821525,0.000037508256,0.000069948226,0.000010025934,0.000037210284,0.00014625698,1.8239243e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013925106,0.00005724979,0.002162019,0.00005954392,0.00007368923,0.0000040699056,0.0000934979,0.0000022954341,0.9958202,0.000010757177,0.0004914791,0.0010859251],"study_design_scores_gemma":[0.00046619654,0.00024461784,0.0010155768,0.000072780706,0.000055165172,0.0004908536,0.00042695043,0.000003202246,0.99568456,0.000046436966,0.0014181063,0.000075532684],"about_ca_topic_score_codex":0.0000031474847,"about_ca_topic_score_gemma":1.6420472e-7,"teacher_disagreement_score":0.006132616,"about_ca_system_score_codex":0.00001480374,"about_ca_system_score_gemma":0.00007984085,"threshold_uncertainty_score":0.2957019},"labels":[],"label_agreement":null},{"id":"W1969959938","doi":"10.1016/s0898-6568(01)00157-7","title":"SH3 ligands in the dopamine D3 receptor","year":2001,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"SH3 domain; GRB2; Signal transducing adaptor protein; Internalization; Receptor; SH2 domain; Cell biology; Biology; G protein-coupled receptor; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Biochemistry","score_opus":0.012932877165506625,"score_gpt":0.22382451564821115,"score_spread":0.21089163848270454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969959938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9704943,0.002812456,0.02486711,0.00014660398,0.00020783451,0.00017151526,0.0000019768702,0.000013367486,0.0012848638],"genre_scores_gemma":[0.9968936,0.00042738573,0.0006488687,0.0003137643,0.00063473324,0.000022236607,0.00010120304,0.000027261525,0.00093094655],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884576,0.000065158114,0.0002515459,0.0003300741,0.00018814545,0.00031930592],"domain_scores_gemma":[0.9995395,0.000023410115,0.00006415801,0.00027539497,0.000041497726,0.000056033357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006198596,0.00016867096,0.00014132244,0.00005114971,0.00010876268,0.000056154287,0.0003462475,0.00014406959,0.00027740723],"category_scores_gemma":[0.000036910442,0.00012934144,0.00010781902,0.00018437975,0.00003049816,0.0000046492746,0.00004927317,0.0001628654,0.00004147979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032885302,0.00004532535,0.00039551008,0.000006243615,0.000012775603,0.000021749616,0.00012553457,0.00039954652,0.9972167,0.00015906847,0.0002910655,0.001293588],"study_design_scores_gemma":[0.0003497935,0.00014803367,0.000023155259,0.00002536484,0.000009191229,0.000013646446,0.0003210032,0.0005365886,0.9392248,0.0001663718,0.05898105,0.00020105166],"about_ca_topic_score_codex":0.000015312073,"about_ca_topic_score_gemma":0.000011107316,"teacher_disagreement_score":0.058689985,"about_ca_system_score_codex":0.000011221171,"about_ca_system_score_gemma":0.000028267626,"threshold_uncertainty_score":0.52743906},"labels":[],"label_agreement":null},{"id":"W1970046535","doi":"10.3109/10799893.2012.759591","title":"G protein-coupled receptor dimers: look like their parents, but act like teenagers!","year":2013,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Receptor; Rhodopsin-like receptors; Effector; Biology; Signal transduction; Function (biology); Cell biology; G protein; Computational biology; Genetics; Metabotropic receptor; Agonist","score_opus":0.008632558071953116,"score_gpt":0.20748965255110857,"score_spread":0.19885709447915545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970046535","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860023,0.0019185451,0.010056004,0.00024070343,0.0013023672,0.00039539058,0.0000071310446,0.000012677279,0.00006483342],"genre_scores_gemma":[0.9937512,0.0016732867,0.0023019423,0.000111760084,0.0011165885,0.000023021452,0.000031818552,0.000044933757,0.0009454168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99831796,0.00013751569,0.0005852315,0.000329706,0.00030122753,0.00032837014],"domain_scores_gemma":[0.9988846,0.00001685595,0.00037912687,0.00016164931,0.00030621243,0.00025156315],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004641429,0.00030016733,0.00036445723,0.00012811007,0.00017203527,0.0001129737,0.00019837405,0.00026904666,0.0017176677],"category_scores_gemma":[0.000018642115,0.00022429318,0.00029813946,0.00012383069,0.000094788236,0.00006478554,0.000025012892,0.00031886552,0.000013145516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022351966,0.000097613425,0.00024162738,0.000033396038,0.00017301981,0.0000013230222,0.0002020466,0.000052831558,0.97635585,0.000008709107,0.0016917197,0.020918343],"study_design_scores_gemma":[0.0012424148,0.001893358,0.00011891948,0.00014506838,0.000067172994,0.00010366142,0.0021038349,0.00015897203,0.94891256,0.00018253355,0.044646997,0.00042451723],"about_ca_topic_score_codex":0.0000426551,"about_ca_topic_score_gemma":0.0000025634467,"teacher_disagreement_score":0.04295528,"about_ca_system_score_codex":0.00003072032,"about_ca_system_score_gemma":0.00008896055,"threshold_uncertainty_score":0.9991949},"labels":[],"label_agreement":null},{"id":"W1970235510","doi":"10.1021/jm0103155","title":"Angiotensin II vs Its Type I Antagonists:  Conformational Requirements for Receptor Binding Assessed from NMR Spectroscopic and Receptor Docking Experiments","year":2002,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"Chemistry; Docking (animal); Stereochemistry; Receptor; Nuclear magnetic resonance spectroscopy; Pharmacology; Biochemistry","score_opus":0.032798085125985574,"score_gpt":0.29050463055950854,"score_spread":0.25770654543352295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970235510","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99480104,0.0030798877,0.00071195164,0.00040891854,0.00059514435,0.00011348384,0.000037262496,0.000005707883,0.00024658118],"genre_scores_gemma":[0.9900269,0.0008593223,0.0061741574,0.00021943955,0.0019038612,0.0000042956804,0.00018606022,0.000026418142,0.0005995321],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986161,0.00002252457,0.00052685,0.00021826116,0.00036499617,0.00025129277],"domain_scores_gemma":[0.9988962,0.000030352561,0.00047793382,0.00012590154,0.000293985,0.00017566654],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00031814398,0.00019367032,0.0002978839,0.000038812002,0.0001848832,0.00004517538,0.00018119128,0.00018381668,0.0012400312],"category_scores_gemma":[0.00022416034,0.00017246997,0.00010038952,0.000064463806,0.00004571248,0.000027612401,0.00006152704,0.00017715522,0.0000054994202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024905722,0.000059905695,0.0002118097,0.000040223225,0.0001262372,0.0000035310559,0.00014968021,0.0000034571074,0.98836195,0.0000052391524,0.010386573,0.00040231537],"study_design_scores_gemma":[0.0017573768,0.00061855733,0.00002642314,0.0002358502,0.00004533344,0.000042867567,0.0003512504,0.0002006459,0.96237373,0.000017116592,0.034156807,0.00017405536],"about_ca_topic_score_codex":0.0000020540665,"about_ca_topic_score_gemma":1.2674057e-7,"teacher_disagreement_score":0.025988253,"about_ca_system_score_codex":0.00006804936,"about_ca_system_score_gemma":0.00007838683,"threshold_uncertainty_score":0.99967295},"labels":[],"label_agreement":null},{"id":"W1970430112","doi":"10.1111/j.1600-0854.2007.00691.x","title":"Distinct Motifs of Neuropeptide Y Receptors Differentially Regulate Trafficking and Desensitization","year":2007,"lang":"en","type":"article","venue":"Traffic","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Internalization; Biology; G protein-coupled receptor; Receptor; Cell biology; Arrestin; Endosome; Adenylyl cyclase; G protein; Signal transducing adaptor protein; Signal transduction; Neuropeptide Y receptor; Molecular biology; Biochemistry; Neuropeptide","score_opus":0.00802433011518175,"score_gpt":0.22127120938352443,"score_spread":0.21324687926834268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970430112","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98729545,0.00013967339,0.012099062,0.000012064278,0.00018060897,0.00009726288,0.0000021776787,0.000020427004,0.00015329591],"genre_scores_gemma":[0.99865973,0.000046233436,0.0009007873,0.000017942795,0.00012326901,7.823489e-7,0.000051157505,0.000024277413,0.00017582996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992118,0.00003703959,0.00022917736,0.00023516982,0.00010523953,0.00018158466],"domain_scores_gemma":[0.99963796,0.000015259444,0.00008930334,0.00013705522,0.000053279105,0.000067117675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024268441,0.00011819634,0.00012872988,0.00004514226,0.000057290563,0.000015398387,0.00006733152,0.00008657631,0.00003080678],"category_scores_gemma":[0.00003930154,0.00011114166,0.000053322496,0.00007451562,0.000053619122,0.0000030929361,0.00003171538,0.00005201536,0.000001180324],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060872164,0.00003114794,0.00030653825,0.000019157178,0.00001922675,0.0000027620124,0.00015000121,0.0012370418,0.9606656,0.0000818687,0.000049837876,0.03737594],"study_design_scores_gemma":[0.00068305776,0.00038421128,0.018681291,0.000052287032,0.00004058877,0.000026915022,0.00014438239,0.0022630673,0.9754639,0.000020910824,0.0019350848,0.00030426678],"about_ca_topic_score_codex":0.0000036013646,"about_ca_topic_score_gemma":0.000034059733,"teacher_disagreement_score":0.03707167,"about_ca_system_score_codex":0.0000050318345,"about_ca_system_score_gemma":0.0000130329045,"threshold_uncertainty_score":0.4532225},"labels":[],"label_agreement":null},{"id":"W1971272118","doi":"10.1016/j.ab.2004.11.036","title":"Analysis of glycoprotein hormone receptor extracellular domain interactions using a solid-phase capture assay","year":2004,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Follicle-stimulating hormone receptor; Receptor; Glycoprotein; Extracellular; Ligand binding assay; Chemistry; Small molecule; Ligand (biochemistry); Hormone receptor; Biophysics; Biochemistry; Biology; Hormone; Follicle-stimulating hormone; Luteinizing hormone","score_opus":0.013307483113115344,"score_gpt":0.3097866370069601,"score_spread":0.2964791538938447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971272118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8912702,0.0009301071,0.10717773,0.000089853966,0.000050455612,0.00010436615,0.00009745731,0.0000137179795,0.00026606597],"genre_scores_gemma":[0.99163085,0.000034777724,0.0071536275,0.000056401397,0.00017476389,0.000009226376,0.0004843209,0.00002619234,0.0004298152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830395,0.00004482951,0.0005012566,0.0005452756,0.0002643645,0.00034029756],"domain_scores_gemma":[0.99887896,0.000017109782,0.00019512938,0.0005279236,0.00016620592,0.00021469824],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031093913,0.00026112684,0.00042854814,0.00013155963,0.00009415609,0.000033446526,0.00024202265,0.00031798682,0.00042359266],"category_scores_gemma":[0.00014499134,0.00025348846,0.0005100951,0.0006250705,0.00013590936,0.000007324402,0.000097611315,0.0002144043,0.00000808113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013319288,0.00030497747,0.000039714178,0.000018539933,0.0010971574,0.000010437746,0.00004462081,0.0014432633,0.9965009,0.00014075903,0.00009693489,0.00016951327],"study_design_scores_gemma":[0.00087820174,0.00012763734,0.000007911884,0.000028552864,0.0006187594,0.000012097209,0.00026991495,0.0030701044,0.99374694,0.00011038125,0.00083596073,0.0002935198],"about_ca_topic_score_codex":0.00010360797,"about_ca_topic_score_gemma":0.000008787675,"teacher_disagreement_score":0.10036063,"about_ca_system_score_codex":0.00007206508,"about_ca_system_score_gemma":0.00013682665,"threshold_uncertainty_score":0.9999917},"labels":[],"label_agreement":null},{"id":"W1971311266","doi":"10.1016/j.bbr.2013.03.026","title":"Dopamine D1 receptors are not critical for opiate reward but can mediate opiate memory retrieval in a state-dependent manner","year":2013,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Occupational Cancer Research Centre; University of Toronto","funders":"National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Opiate; Dopamine; Opiate receptors; Neuroscience; Dopamine receptor D2; Dopamine receptor; Psychology; Dopamine receptor D3; Receptor; Medicine; Internal medicine; Antagonist; (+)-Naloxone","score_opus":0.07182628196636252,"score_gpt":0.3566260263502529,"score_spread":0.2847997443838904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971311266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99200165,0.00023377175,0.00015723018,0.0056374297,0.00048880884,0.0012180089,0.00018382329,0.000025450096,0.00005381178],"genre_scores_gemma":[0.9891731,0.000118056436,0.000737368,0.00032388524,0.00031231996,0.00036214228,0.00025126588,0.000084463274,0.008637357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99602306,0.00050532806,0.00055339554,0.0008467367,0.0008161365,0.0012553412],"domain_scores_gemma":[0.9980653,0.00027433244,0.00008687656,0.000502828,0.00065555883,0.00041512752],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0023849907,0.00030156094,0.00036426075,0.0002559844,0.00023557077,0.00017530334,0.0005457047,0.00034402317,0.00050827576],"category_scores_gemma":[0.0017521931,0.00027356594,0.00016690271,0.00024795166,0.00022509995,0.000021556922,0.00036585904,0.0005876806,0.00005857951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053838396,0.00016709168,0.0033032817,0.0000786387,0.0000268506,0.00005281812,0.00016899627,0.00003560841,0.98772556,0.0000709482,0.004840283,0.0029915513],"study_design_scores_gemma":[0.0022207147,0.0011849774,0.008710299,0.00010615618,0.000013885139,0.00001846326,0.0012217633,0.0002602976,0.9834533,0.0005998006,0.0016148821,0.0005954646],"about_ca_topic_score_codex":0.001828284,"about_ca_topic_score_gemma":0.00071614113,"teacher_disagreement_score":0.008583545,"about_ca_system_score_codex":0.00013507997,"about_ca_system_score_gemma":0.00018941502,"threshold_uncertainty_score":0.9999716},"labels":[],"label_agreement":null},{"id":"W1971412466","doi":"10.1016/j.lfs.2003.09.016","title":"Continued discovery of ligands for G protein-coupled receptors","year":2003,"lang":"en","type":"review","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Receptor; G protein-coupled receptor; Computational biology; Drug discovery; Biology; Pharmacology; Biochemistry","score_opus":0.039102166145696456,"score_gpt":0.318233325530688,"score_spread":0.27913115938499156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971412466","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013722978,0.99513507,0.0016516045,0.0000050608983,0.0006305032,0.0009497785,0.00004075141,0.000005506553,0.00020941261],"genre_scores_gemma":[0.00037475492,0.9948638,0.0017512141,0.00003132448,0.00028151434,0.00019369088,0.000079489255,0.000025589741,0.002398618],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99851817,0.000037976468,0.00047328978,0.0005007664,0.0001953944,0.000274405],"domain_scores_gemma":[0.99917734,0.000026921913,0.00043947206,0.00022042202,0.000067403074,0.00006847203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072404684,0.00025087426,0.0007622358,0.00007467009,0.00012009068,0.000049564995,0.00042457835,0.0002643554,0.00004068714],"category_scores_gemma":[0.00026462585,0.00017825217,0.0004526142,0.00022016474,0.00019187573,0.000007020451,0.000057264733,0.000069067384,0.0000030942397],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000102541584,0.00033551664,0.000026533517,0.024404438,0.00084437104,0.000001821948,0.000121607045,0.00002235939,0.43161258,0.006494078,0.01088199,0.52515215],"study_design_scores_gemma":[0.00013587561,0.00041259333,4.6873712e-8,0.00132313,0.000086344844,0.0000019153954,0.000037320882,0.0000058058777,0.050066043,0.0000913409,0.9475766,0.00026300253],"about_ca_topic_score_codex":0.0000048921975,"about_ca_topic_score_gemma":0.0000019590625,"teacher_disagreement_score":0.93669456,"about_ca_system_score_codex":0.000006892854,"about_ca_system_score_gemma":0.0005425911,"threshold_uncertainty_score":0.7268913},"labels":[],"label_agreement":null},{"id":"W1971562588","doi":"10.1016/j.bmcl.2009.03.010","title":"Discovery of potent and selective DP1 receptor antagonists in the azaindole series","year":2009,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Receptor; Pharmacology; Stereochemistry; Biochemistry; Biology","score_opus":0.004785617523555949,"score_gpt":0.2083990507083683,"score_spread":0.20361343318481237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971562588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942809,0.0007185538,0.0003603303,0.004274686,0.00006257206,0.00011747144,0.000010181052,0.0000056435365,0.00016968418],"genre_scores_gemma":[0.9979012,0.00020759345,0.00018954022,0.001272987,0.000302045,0.0000046896475,0.000051983672,0.000010661609,0.000059272184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990114,0.000045132634,0.00022827908,0.00029335625,0.00019846638,0.00022336518],"domain_scores_gemma":[0.99960536,0.000013702698,0.00009871274,0.00021083362,0.000028706101,0.000042690433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002639391,0.00016779773,0.00018269867,0.000017797287,0.00005566019,0.00002215538,0.00020257654,0.00010622361,0.000015148416],"category_scores_gemma":[0.000063913656,0.0001236329,0.000053019437,0.00011884861,0.00012307349,0.000009571639,0.000032264703,0.00014681794,6.7859133e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010802121,0.000039826555,0.000329511,0.000028963585,0.000018373774,0.00000792532,0.0002513374,0.0000012761687,0.99745685,0.000016713868,0.0010744353,0.0006667902],"study_design_scores_gemma":[0.0004388269,0.00016252632,0.0018283754,0.00004536747,0.000016043517,0.00008220804,0.0007779228,0.000002125715,0.9956795,0.000042298194,0.000783242,0.00014159417],"about_ca_topic_score_codex":0.000014845772,"about_ca_topic_score_gemma":0.0000019764059,"teacher_disagreement_score":0.0036203496,"about_ca_system_score_codex":0.000022856784,"about_ca_system_score_gemma":0.000051059345,"threshold_uncertainty_score":0.5041603},"labels":[],"label_agreement":null},{"id":"W1971808954","doi":"10.1016/j.coph.2009.09.011","title":"Heteromerization of dopamine D2 receptors with dopamine D1 or D5 receptors generates intracellular calcium signaling by different mechanisms","year":2009,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"National Institute on Drug Abuse; Canada Research Chairs","keywords":"Dopamine; Dopamine receptor; Dopamine receptor D2; Receptor; Intracellular; D1-like receptor; D2-like receptor; Calcium in biology; Calcium; Dopamine receptor D3; Chemistry; Cell biology; Neuroscience; Biology; Biochemistry","score_opus":0.051339560548456335,"score_gpt":0.35337356564234984,"score_spread":0.3020340050938935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971808954","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004961785,0.9630265,0.02245555,0.000021093036,0.007970987,0.0014604451,0.00007510033,0.00002429481,0.000004225635],"genre_scores_gemma":[0.0018511917,0.99200356,0.000477613,0.000017172082,0.00081052544,0.00032717266,0.0042758677,0.00011461109,0.00012230163],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99588406,0.00066783535,0.0014533137,0.0010546868,0.00029544832,0.00064465275],"domain_scores_gemma":[0.9984715,0.000075835706,0.00086545007,0.00030554787,0.00011042594,0.00017123939],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041045347,0.0008368916,0.0017951528,0.0004625159,0.000072391646,0.000034179855,0.00048804336,0.0006184676,0.00065679365],"category_scores_gemma":[0.00003336444,0.00063437305,0.0002692256,0.00055149366,0.00011733355,0.0000141143155,0.00014451648,0.00059193926,0.0000049337273],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040370278,0.0010117587,0.00002682819,0.007254373,0.0002509236,0.0000049438913,0.000055023553,0.0004181462,0.39778167,0.000044530192,0.0023499196,0.5903982],"study_design_scores_gemma":[0.0015631358,0.0013236266,3.8802565e-7,0.0037419968,0.0001806049,0.000021039034,0.000023638568,0.00015238569,0.2745813,0.000014338785,0.7176262,0.0007713276],"about_ca_topic_score_codex":0.000009431292,"about_ca_topic_score_gemma":0.0000032851494,"teacher_disagreement_score":0.7152763,"about_ca_system_score_codex":0.00014971558,"about_ca_system_score_gemma":0.00025044993,"threshold_uncertainty_score":0.9996108},"labels":[],"label_agreement":null},{"id":"W1971809862","doi":"10.1002/ddr.10288","title":"Pharmacogenomics and animal models of schizophrenia","year":2003,"lang":"en","type":"article","venue":"Drug Development Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Endophenotype; Schizophrenia (object-oriented programming); Pharmacogenomics; Disease; DISC1; Candidate gene; Neuroscience; Computational biology; Psychology; Genetics; Biology; Bioinformatics; Gene; Medicine; Psychiatry; Cognition; Pathology","score_opus":0.050632138803002325,"score_gpt":0.32206998893742933,"score_spread":0.271437850134427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971809862","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99561846,0.0010954925,0.0009791446,0.000021105643,0.000032729917,0.00013039501,0.0000021418816,0.0000032571597,0.002117277],"genre_scores_gemma":[0.9863931,0.000354099,0.01252315,0.000014209791,0.000029148448,0.000014952882,0.0000139740205,0.000013745938,0.00064362556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900347,0.00010569453,0.00016545123,0.00024021386,0.00022964821,0.0002555509],"domain_scores_gemma":[0.9996173,0.000014201769,0.000026330312,0.00011603765,0.00013989028,0.000086259235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010853509,0.000083023144,0.000094235285,0.00007651142,0.000114166054,0.0000189088,0.00011706884,0.00005363235,0.000067192734],"category_scores_gemma":[0.00003573095,0.00007810549,0.00002165798,0.00009430066,0.000059748483,0.000003733131,0.00010917576,0.00010506245,0.0000048876427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000087764325,0.000029707455,0.00019123248,0.0000203878,0.000029279207,0.0000012807424,0.00021436492,0.000032367934,0.9930466,0.0028494934,0.0003752256,0.003122335],"study_design_scores_gemma":[0.00038207055,0.000039374896,0.000057307767,0.000008355118,0.0000016520532,0.0000040229806,0.00015487825,0.00013266716,0.97950584,0.0005428022,0.019075138,0.0000958857],"about_ca_topic_score_codex":0.0000052516216,"about_ca_topic_score_gemma":0.000003365614,"teacher_disagreement_score":0.018699912,"about_ca_system_score_codex":0.0000132217965,"about_ca_system_score_gemma":0.00024561415,"threshold_uncertainty_score":0.31850493},"labels":[],"label_agreement":null},{"id":"W1971908268","doi":"10.1007/s12031-011-9678-0","title":"Colocalization of Somatostatin Receptors with DARPP-32 in Cortex and Striatum of Rat Brain","year":2011,"lang":"en","type":"article","venue":"Journal of Molecular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Colocalization; Striatum; Somatostatin receptor; Excitotoxicity; Neuroscience; Dopamine; Biology; Somatostatin; Cortex (anatomy); Basal ganglia; Somatostatin receptor 1; Internal medicine; Receptor; Somatostatin receptor 2; Glutamate receptor; Medicine; Central nervous system; Biochemistry","score_opus":0.010914314686778172,"score_gpt":0.22149929084631384,"score_spread":0.21058497615953567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971908268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9701553,0.00016916302,0.02936749,0.000023075472,0.00016142495,0.00007673209,0.0000014240073,8.2206736e-7,0.000044567332],"genre_scores_gemma":[0.9972338,0.00009619562,0.0025301394,0.00011067043,0.000007893653,6.172903e-7,9.102723e-7,0.000007609423,0.000012157582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990819,0.00009098774,0.00035171385,0.00014688463,0.00021636985,0.00011211332],"domain_scores_gemma":[0.99926513,0.000010721268,0.00042961023,0.0001060864,0.00012980118,0.000058647413],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003485925,0.00008316016,0.00017321845,0.00009511138,0.000018130972,0.000007406113,0.00015838289,0.000051914452,0.0000070745796],"category_scores_gemma":[0.00018948308,0.00006700061,0.00003928257,0.00019568262,0.00013234848,0.000011500425,0.000040234678,0.00007126703,3.8113686e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015770293,0.00005525923,0.0033469035,0.000014907257,0.0000036259953,0.000016954906,0.000116104326,0.00018555736,0.99548316,0.00016784656,0.000027962762,0.00042403015],"study_design_scores_gemma":[0.0005401553,0.0018002831,0.0023177844,0.00005499691,0.00000841233,0.000060961953,0.00011003901,0.00018389264,0.994569,0.00010140623,0.00018340664,0.000069654416],"about_ca_topic_score_codex":0.000007966932,"about_ca_topic_score_gemma":0.0000051471557,"teacher_disagreement_score":0.027078504,"about_ca_system_score_codex":0.0000044675144,"about_ca_system_score_gemma":0.000106654086,"threshold_uncertainty_score":0.27322057},"labels":[],"label_agreement":null},{"id":"W1972109266","doi":"10.1203/01.pdr.0000099749.83960.cf","title":"The Role of PKCδ and PKCε in the Neonatal Rat Colon in Response to Hypoxia Challenge","year":2003,"lang":"en","type":"article","venue":"Pediatric Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Protein kinase C; Hypoxia (environmental); Gene isoform; Internal medicine; Endocrinology; Prostaglandin E2; Cytosol; Prostaglandin; Inflammation; Intestinal mucosa; Chemistry; Biology; Kinase; Medicine; Cell biology; Enzyme; Biochemistry","score_opus":0.021297614313546445,"score_gpt":0.3122162601555869,"score_spread":0.29091864584204047,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972109266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98943025,0.009159592,0.000015649053,0.00046620192,0.000036674435,0.00030746343,0.0000023299021,0.0000010133392,0.0005808151],"genre_scores_gemma":[0.9966561,0.0029491782,0.0000699639,0.000020006786,0.00008399283,0.00005749014,0.0000017392663,0.000008161,0.00015336314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980945,0.0009254172,0.00016845202,0.00021071518,0.00029301003,0.0003078955],"domain_scores_gemma":[0.999246,0.0003699747,0.000023043776,0.00024258705,0.000069190464,0.00004918853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0050408742,0.0000676455,0.00008267512,0.00011902484,0.000099588775,0.000028687879,0.00025253277,0.00008715353,0.000010880793],"category_scores_gemma":[0.0009673539,0.000043203,0.000024317558,0.00036752256,0.000047036094,0.0000025912327,0.000098109136,0.00020453884,0.000003837406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020648632,0.000142348,0.011224518,0.000028965977,0.000009221791,0.000024587293,0.002508499,0.00004934664,0.9634616,0.003097145,0.0008466754,0.016542278],"study_design_scores_gemma":[0.0032252423,0.0043243878,0.021784278,0.000025237348,0.0000142381805,0.000039235285,0.015018598,0.00017545269,0.5514817,0.011945327,0.39138523,0.0005810542],"about_ca_topic_score_codex":0.00005259506,"about_ca_topic_score_gemma":0.0001421936,"teacher_disagreement_score":0.41197982,"about_ca_system_score_codex":0.000013037969,"about_ca_system_score_gemma":0.00011288338,"threshold_uncertainty_score":0.17617673},"labels":[],"label_agreement":null},{"id":"W1972506323","doi":"10.1097/aln.0b013e31818d4942","title":"β3-Adrenergic Receptor Subtype Signaling In Senescent Heart","year":2008,"lang":"en","type":"letter","venue":"Anesthesiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"","keywords":"Medicine; Adrenergic receptor; Adrenergic; Alpha-1B adrenergic receptor; Alpha-1D adrenergic receptor; Receptor; Alpha-1A adrenergic receptor; Signal transduction; Internal medicine; Endocrinology; Cell biology; Beta-3 adrenergic receptor; Biology","score_opus":0.015370873927442227,"score_gpt":0.22580936986583047,"score_spread":0.21043849593838826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972506323","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9742625,0.0034503988,0.00003077837,0.020802662,0.0008271976,0.00035603633,0.000014450375,0.000041065876,0.00021493131],"genre_scores_gemma":[0.33374304,0.0032035057,0.0017074889,0.64368963,0.010002792,0.00015005817,0.003678232,0.00029959035,0.0035256706],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971571,0.00041181548,0.000529973,0.0009482086,0.0001985765,0.0007543464],"domain_scores_gemma":[0.99900293,0.00005571094,0.00020030778,0.00057770824,0.00008606374,0.00007729321],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00026005344,0.00050010957,0.0006787122,0.00018587775,0.000098402095,0.000018262219,0.00041409116,0.0021136813,0.0003951304],"category_scores_gemma":[0.000059196624,0.00047857405,0.00027447921,0.00013882236,0.00012237279,0.0000032071962,0.00007740134,0.00092007313,0.0001578628],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007476956,0.00003721976,0.0029886866,0.0000442019,0.00003935971,0.0004043925,0.00004035502,0.00012793385,0.48872283,0.000008859547,0.5073062,0.00020519341],"study_design_scores_gemma":[0.00030955265,0.0004569341,0.00031345864,0.000053679443,0.000013404003,0.00029662086,0.000016312304,0.000005693311,0.16424201,0.000054284417,0.83370733,0.00053068926],"about_ca_topic_score_codex":0.00013401777,"about_ca_topic_score_gemma":0.00001386091,"teacher_disagreement_score":0.64051944,"about_ca_system_score_codex":0.00004658222,"about_ca_system_score_gemma":0.0002311549,"threshold_uncertainty_score":0.9997666},"labels":[],"label_agreement":null},{"id":"W1972599822","doi":"10.1016/j.bbrc.2011.01.050","title":"The role of palmitoylation in directing dopamine D1 receptor internalization through selective endocytic routes","year":2011,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada","keywords":"Internalization; Clathrin; Palmitoylation; Caveolae; Cell biology; Endocytic cycle; Agonist; Receptor; Endosome; Biology; Chemistry; Biochemistry; Endocytosis; Signal transduction; Enzyme","score_opus":0.05432422085544664,"score_gpt":0.3318383749470941,"score_spread":0.2775141540916475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972599822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942616,0.0026582,0.00042418542,0.00010821949,0.000021801667,0.00023153986,0.000009059871,0.0000078609255,0.0022775102],"genre_scores_gemma":[0.9960945,0.001977988,0.0016906537,0.000007626626,0.00006129787,0.000054892058,0.000058935322,0.000009525681,0.000044580127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895996,0.00023753656,0.0002235696,0.00019890476,0.00017257239,0.00020744164],"domain_scores_gemma":[0.99900246,0.00021652775,0.000064762746,0.0004195976,0.000249537,0.000047099253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040003104,0.000084136685,0.00010296646,0.000034312812,0.00020516195,0.000022505956,0.00041255602,0.00008411013,0.000007935229],"category_scores_gemma":[0.0004715657,0.00006142648,0.00004188581,0.00026874547,0.00035740476,0.000009928344,0.0003275471,0.00021888105,0.0000028156721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007029314,0.000121214085,0.0007374444,0.0000060221155,0.000016700906,5.3711283e-8,0.0002768776,2.4301102e-7,0.9871884,0.006763688,0.000028687035,0.004790371],"study_design_scores_gemma":[0.00014715032,0.0001588618,0.0004332888,0.000032745724,0.000004070479,8.0897905e-7,0.0005582078,0.00053042005,0.99010575,0.0056306333,0.0023246077,0.000073476884],"about_ca_topic_score_codex":0.00028396325,"about_ca_topic_score_gemma":0.000033988905,"teacher_disagreement_score":0.0047168937,"about_ca_system_score_codex":0.000024447805,"about_ca_system_score_gemma":0.00004117566,"threshold_uncertainty_score":0.25048992},"labels":[],"label_agreement":null},{"id":"W1972929252","doi":"10.1016/s0169-328x(00)00064-4","title":"The human dopamine D2Longer receptor has a high-affinity state and inhibits adenylyl cyclase","year":2000,"lang":"en","type":"article","venue":"Molecular Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Adenylyl cyclase; Dopamine; Dopamine receptor; Dopamine receptor D2; Dopamine receptor D1; ADCY9; Receptor; D1-like receptor; D2-like receptor; Biochemistry; Endocrinology","score_opus":0.02951354677213657,"score_gpt":0.31367241850409255,"score_spread":0.284158871731956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972929252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942873,0.001470351,0.00023878831,0.0025383392,0.000052726962,0.00041432513,0.000023633558,0.000015591299,0.0009589501],"genre_scores_gemma":[0.9870329,0.00040646343,0.0003869118,0.00032149145,0.00016768015,0.000082340826,0.00009904778,0.000056425397,0.0114467265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971424,0.000656809,0.0002867075,0.00061808043,0.00057318766,0.00072283065],"domain_scores_gemma":[0.99879855,0.0001089102,0.000042751537,0.00060534856,0.00020236723,0.00024205248],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019471245,0.00022716187,0.00017824824,0.00008082553,0.0010053744,0.00034270328,0.0003910326,0.00017579281,0.0007664498],"category_scores_gemma":[0.00031930918,0.0001734876,0.00009045142,0.00024328135,0.00045631552,0.000007259263,0.0002681444,0.00043867546,0.000109408546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012990032,0.0000534848,0.000028068784,0.00001262859,0.00004867291,0.000028717566,0.000083016086,0.000026436112,0.9770674,0.00037780224,0.0070533077,0.015090576],"study_design_scores_gemma":[0.00068263424,0.00055016874,0.00014919123,0.00002198079,0.000004536041,0.000013628113,0.000064671956,0.00003576093,0.8922611,0.0011805507,0.10480689,0.000228893],"about_ca_topic_score_codex":0.00013750122,"about_ca_topic_score_gemma":0.00008363958,"teacher_disagreement_score":0.097753584,"about_ca_system_score_codex":0.000025455469,"about_ca_system_score_gemma":0.00010844358,"threshold_uncertainty_score":0.8392087},"labels":[],"label_agreement":null},{"id":"W1973068164","doi":"10.1016/j.bbamem.2005.02.004","title":"Agonist-induced up-regulation of human somatostatin receptor type 1 is regulated by β-arrestin-1 and requires an essential serine residue in the receptor C-tail","year":2005,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital","funders":"","keywords":"Internalization; Somatostatin receptor; Receptor; Agonist; 5-HT5A receptor; G protein-coupled receptor; Biology; Enzyme-linked receptor; Forskolin; Cell biology; G protein-coupled receptor kinase; Somatostatin; Arrestin; Mutant; Beta adrenergic receptor kinase; Somatostatin receptor 2; Somatostatin receptor 1; Serine; Biochemistry; Phosphorylation; Endocrinology","score_opus":0.014293650051360806,"score_gpt":0.27470185459893526,"score_spread":0.26040820454757446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973068164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972403,0.00016283651,0.000007389488,0.0016596016,0.0001736723,0.00052115665,0.00014494055,0.000036439797,0.00005368459],"genre_scores_gemma":[0.9966237,0.00019700287,0.0005387938,0.00026611876,0.00038829117,0.00003347822,0.0015882112,0.00006243471,0.00030195795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99763036,0.0003119812,0.0006126027,0.00071745506,0.00033563297,0.0003919942],"domain_scores_gemma":[0.9986995,0.000037544978,0.0003743058,0.0006292618,0.00014349182,0.000115916104],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00040399597,0.00039542202,0.00037930682,0.00014064231,0.00020988856,0.000114440445,0.00045673657,0.00032092218,0.00014582844],"category_scores_gemma":[0.00004714321,0.00032666494,0.00011047039,0.0004293486,0.00022598947,0.000051683288,0.00012117941,0.0001636909,0.000008573372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003625287,0.0002297397,0.000010248959,0.00006615212,0.000058002744,3.8448078e-7,0.0008677452,0.0000036520632,0.9945598,0.00012200702,0.002972727,0.0007470022],"study_design_scores_gemma":[0.0008862301,0.00075533753,0.0007530834,0.00006773247,0.000031670646,0.000005777012,0.00032685717,0.00012987,0.9948382,0.00008258978,0.0017180388,0.00040462517],"about_ca_topic_score_codex":0.00018987586,"about_ca_topic_score_gemma":0.00006173528,"teacher_disagreement_score":0.0014432706,"about_ca_system_score_codex":0.000019510288,"about_ca_system_score_gemma":0.00008432801,"threshold_uncertainty_score":0.9999185},"labels":[],"label_agreement":null},{"id":"W1973552252","doi":"10.1074/jbc.m212302200","title":"Agonist-independent Desensitization and Internalization of the Human Platelet-activating Factor Receptor by Coumermycin-Gyrase B-induced Dimerization","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Internalization; G protein-coupled receptor; Cell biology; Receptor; Agonist; Biology; Platelet-activating factor; Chemistry; Protein kinase C; Arrestin; Kinase; Biochemistry; Signal transduction; Endocrinology","score_opus":0.018226678897309286,"score_gpt":0.24831259956762616,"score_spread":0.23008592067031688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973552252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99122787,0.00020617012,0.008249053,0.00001878036,0.00010640547,0.00006494328,0.000010750612,0.0000027465824,0.00011326651],"genre_scores_gemma":[0.99941874,0.00010821917,0.00024566017,0.000040234398,0.00009034776,0.0000010751814,0.00003685617,0.000009849477,0.000049044025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991049,0.000093396666,0.00038905034,0.00015020696,0.00015100083,0.00011140654],"domain_scores_gemma":[0.99909663,0.000018485105,0.000560382,0.000099615485,0.00016256978,0.000062294086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020816036,0.000120954624,0.00017048599,0.000011402433,0.00009011244,0.000021458032,0.000113362665,0.00020738905,0.00011178672],"category_scores_gemma":[0.00033553713,0.000080042126,0.00008632233,0.00006359884,0.000049563132,0.000007672669,0.000037954633,0.00014160907,1.61548e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027975591,0.000040553423,0.002474239,0.000015340449,0.000031013915,6.216256e-7,0.00002528042,0.000015577036,0.996717,0.000029372983,0.0000490912,0.0005739696],"study_design_scores_gemma":[0.00034934285,0.00013985262,0.00036933567,0.000037358892,0.0000048317374,0.000034878874,0.00009912531,0.000015470834,0.99740744,0.000065709275,0.0013812252,0.00009544474],"about_ca_topic_score_codex":0.000002566703,"about_ca_topic_score_gemma":2.067359e-7,"teacher_disagreement_score":0.008190829,"about_ca_system_score_codex":0.000021857724,"about_ca_system_score_gemma":0.00003509918,"threshold_uncertainty_score":0.32640234},"labels":[],"label_agreement":null},{"id":"W1973561132","doi":"10.1111/j.1582-4934.2003.tb00228.x","title":"Attenuation of changes in G<sub>i</sub>‐proteins and adenylyl cyclase in heart failure by an ACE inhibitor, imidapril","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Heart and Stroke Foundation of Canada","keywords":"Adenylyl cyclase; Heart failure; Internal medicine; Ventricle; Pertussis toxin; Cholera toxin; Endocrinology; Cardiac function curve; Myocardial infarction; Medicine; ACE inhibitor; G protein; Receptor; Angiotensin-converting enzyme; Cardiology; Chemistry; Blood pressure","score_opus":0.005580353984095528,"score_gpt":0.21854551575358483,"score_spread":0.2129651617694893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973561132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981331,0.010516904,0.0071822326,0.0007484456,0.00006958034,0.00013469526,0.0000023310852,0.0000010838328,0.000013708758],"genre_scores_gemma":[0.9977721,0.0009953401,0.00090699084,0.00019707573,0.00008667407,0.0000028566915,0.000017466615,0.000016209193,0.00000529856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892676,0.00015840444,0.00036307992,0.00018313913,0.00021129078,0.00015730702],"domain_scores_gemma":[0.99947363,0.000009853889,0.00018793996,0.00011594004,0.0000876108,0.00012501098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007174276,0.00013909876,0.00030090197,0.00014998563,0.000020511374,0.000007226938,0.000055868768,0.00015155556,0.000008592444],"category_scores_gemma":[0.00012934404,0.000118121134,0.00003683081,0.000107964326,0.00007152534,0.000010795174,0.000019887551,0.00016434454,1.1379895e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057608173,0.00005700368,0.0005032041,0.00003586827,0.000014719371,0.000032078835,0.00015035555,0.000023167153,0.99823284,0.000043193577,0.00016952964,0.00068040687],"study_design_scores_gemma":[0.0016757969,0.0010571278,0.00014991862,0.00016944758,0.000023192937,0.00007951989,0.00039632493,0.000032852182,0.99308324,0.000110680536,0.0031107797,0.0001111241],"about_ca_topic_score_codex":0.000014009874,"about_ca_topic_score_gemma":0.000049626546,"teacher_disagreement_score":0.01644107,"about_ca_system_score_codex":0.000010981933,"about_ca_system_score_gemma":0.000042788364,"threshold_uncertainty_score":0.481684},"labels":[],"label_agreement":null},{"id":"W1973700350","doi":"10.1016/j.bbamem.2007.01.024","title":"Erratum to “Conformation of a double-membrane-spanning fragment of a G protein-coupled receptor: Effects of hydrophobic environment and pH” [Biochim. Biophys. Acta 1768 (2007) 1199–1210]","year":2007,"lang":"en","type":"erratum","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Health Sciences Centre","funders":"","keywords":"Chemistry; Fragment (logic); Biophysics; Membrane; Biochemistry; Biology; Computer science","score_opus":0.00700302266352693,"score_gpt":0.22736792504083692,"score_spread":0.22036490237731,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973700350","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99101543,0.0021402892,0.00013068822,0.00021662902,0.0028495064,0.0026945157,0.00036911818,0.00004284799,0.00054095866],"genre_scores_gemma":[0.9872073,0.004316155,0.0013771672,0.00015974222,0.0009042831,0.00020728442,0.0024643063,0.00022362707,0.0031401373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9945871,0.00018347181,0.0018178977,0.0014258398,0.0010569245,0.000928727],"domain_scores_gemma":[0.99580497,0.00007246965,0.0020890073,0.0013698633,0.00026135982,0.00040235443],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0006491846,0.0013146295,0.0018705984,0.00084571866,0.00015939264,0.000060641923,0.0009450844,0.0014593652,0.00008412533],"category_scores_gemma":[0.000061224026,0.0012133993,0.0007004584,0.0006401459,0.00050650147,0.00004701946,0.0006488721,0.0006066768,0.000011954443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001428852,0.0005581001,5.4546166e-7,0.004002141,0.00070338394,0.000003392564,0.0006847006,0.000019296085,0.9855212,0.000027087834,0.0067969984,0.00025432438],"study_design_scores_gemma":[0.0021853596,0.0023916876,0.000056893816,0.0016306551,0.0003066249,0.000008490295,0.00015741553,0.00013175956,0.97835964,0.000021585098,0.013614921,0.0011349645],"about_ca_topic_score_codex":0.00022071466,"about_ca_topic_score_gemma":0.000007451772,"teacher_disagreement_score":0.0071615353,"about_ca_system_score_codex":0.00008348622,"about_ca_system_score_gemma":0.00034348728,"threshold_uncertainty_score":0.99996054},"labels":[],"label_agreement":null},{"id":"W1973704482","doi":"10.1371/journal.pone.0029996","title":"Site-Directed Mutations and the Polymorphic Variant Ala160Thr in the Human Thromboxane Receptor Uncover a Structural Role for Transmembrane Helix 4","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"National Institutes of Health; Manitoba Medical Service Foundation; Manitoba Health Research Council; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; American Heart Association","keywords":"Transmembrane domain; G protein-coupled receptor; Mutant; Helix (gastropod); Biology; Genetics; Receptor; Transmembrane protein; Mutation; Subfamily; Biochemistry; Gene","score_opus":0.02005923753592494,"score_gpt":0.23293552422989933,"score_spread":0.21287628669397438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973704482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968589,0.001519154,0.00023946619,0.00053635123,0.000048480793,0.000616115,0.000059433318,0.00001306493,0.000109040804],"genre_scores_gemma":[0.9974936,0.00007089368,0.0012980526,0.0002975989,0.00031118552,0.00012801621,0.00024226004,0.00002064063,0.00013774062],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990739,0.00014079023,0.00018588189,0.00018736783,0.00014862849,0.0002633881],"domain_scores_gemma":[0.9995747,0.00007097088,0.000058895075,0.00020493334,0.000044345412,0.000046153804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040733913,0.00013467032,0.00018189271,0.000025926292,0.00020601058,0.000039768405,0.00014237418,0.00010084685,0.0001326714],"category_scores_gemma":[0.00005698351,0.0000813752,0.00006661949,0.00008494839,0.00008283623,0.00000973433,0.000023523808,0.000104227394,0.0000030111971],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009236184,0.00013593296,0.00034240205,0.0000237585,0.000108933935,2.1873872e-7,0.0015765076,0.000007398711,0.99630386,0.0012586092,0.00003070862,0.00011929012],"study_design_scores_gemma":[0.003456611,0.00027556604,0.0025286663,0.00005241105,0.00023775827,0.000013228079,0.00072808267,0.0008307958,0.989334,0.0017030159,0.00053798914,0.0003019048],"about_ca_topic_score_codex":0.000087484106,"about_ca_topic_score_gemma":0.00007732751,"teacher_disagreement_score":0.0069699064,"about_ca_system_score_codex":0.000007587156,"about_ca_system_score_gemma":0.000017998342,"threshold_uncertainty_score":0.33183843},"labels":[],"label_agreement":null},{"id":"W1974094353","doi":"10.1016/j.cellsig.2009.09.031","title":"The dopamine D4 receptor activates intracellular platelet-derived growth factor receptor β to stimulate ERK1/2","year":2009,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Platelet-derived growth factor receptor; Downregulation and upregulation; Tunicamycin; Cell biology; Receptor; Biology; G protein-coupled receptor; MAPK/ERK pathway; Signal transduction; Internal medicine; Endocrinology; Growth factor; Biochemistry; Medicine","score_opus":0.01044254744253234,"score_gpt":0.22190257879310632,"score_spread":0.21146003135057398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974094353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9231007,0.0022257974,0.07261707,0.0005640284,0.00061031466,0.0006122855,0.000023964907,0.00008114549,0.0001647039],"genre_scores_gemma":[0.99159217,0.0005266194,0.0049826307,0.00039305355,0.001000951,0.000029989831,0.0002178766,0.00008801796,0.0011686678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971378,0.00016383277,0.00058927847,0.00084783055,0.0004054992,0.00085578754],"domain_scores_gemma":[0.99850625,0.000091721624,0.00021765004,0.0005513171,0.00025787114,0.0003752022],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00052462716,0.00051611115,0.00038555337,0.00009263565,0.00061064627,0.0002462017,0.00070562173,0.00034271722,0.0004452186],"category_scores_gemma":[0.00023421137,0.0004121237,0.00026285442,0.0002693213,0.0000663308,0.00001942645,0.00013218766,0.00035935093,0.00017814993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025614342,0.000062999425,0.00001654116,0.000011696611,0.00009276131,0.000008693605,0.00016180112,0.0009441188,0.986733,0.00016071544,0.0004293594,0.011122146],"study_design_scores_gemma":[0.0005136205,0.00067340164,0.000010755046,0.000052654053,0.000018042587,0.0000037512896,0.00014277274,0.00058381277,0.96178806,0.0002339172,0.03541282,0.00056639215],"about_ca_topic_score_codex":0.000011610051,"about_ca_topic_score_gemma":0.0000028065886,"teacher_disagreement_score":0.0684915,"about_ca_system_score_codex":0.000058817823,"about_ca_system_score_gemma":0.000079205995,"threshold_uncertainty_score":0.99983305},"labels":[],"label_agreement":null},{"id":"W1974926123","doi":"10.1016/j.bmcl.2015.04.008","title":"Discovery of novel small-molecule antagonists for GluK2","year":2015,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chemistry; Glutamate receptor; Receptor; NMDA receptor; Kainate receptor; Neurotransmitter receptor; Docking (animal); Neurotransmitter; Ionotropic effect; Binding site; Small molecule; Pharmacology; Stereochemistry; Neuroscience; Biophysics; Biochemistry; AMPA receptor; Biology","score_opus":0.02898435876292921,"score_gpt":0.25142506348220894,"score_spread":0.22244070471927974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974926123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93780035,0.00047700657,0.060142603,0.0008995163,0.00026769814,0.00017286227,0.000051772535,0.0000140427,0.00017413849],"genre_scores_gemma":[0.9952263,0.000021358588,0.0025800343,0.0007726728,0.0008160529,0.000019034687,0.00025896926,0.000041623192,0.0002639511],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987356,0.000013111245,0.00031454803,0.0003988479,0.00022839691,0.0003094663],"domain_scores_gemma":[0.99921155,0.0000161259,0.00016836233,0.00033753508,0.00011278993,0.00015364686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028705513,0.00021887699,0.00025046573,0.000019014717,0.000044527354,0.000020823969,0.00030493387,0.00016354186,0.000021993877],"category_scores_gemma":[0.00019333912,0.00020197344,0.00013445527,0.00008543355,0.0001220916,0.000005578248,0.00008444112,0.00009510618,0.0000014601399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015149101,0.00007372885,0.00008563786,0.00009700703,0.00006279393,0.0000035572864,0.00004843757,0.0000054228963,0.9958457,0.000017000946,0.003520988,0.00008827714],"study_design_scores_gemma":[0.0016235262,0.00013503795,0.000015844642,0.0000447308,0.000049189348,0.000042791493,0.00023752605,0.00004224348,0.9943636,0.000010145431,0.0032065003,0.0002288632],"about_ca_topic_score_codex":0.000018995088,"about_ca_topic_score_gemma":0.0000014908173,"teacher_disagreement_score":0.05756257,"about_ca_system_score_codex":0.000036595848,"about_ca_system_score_gemma":0.00017733405,"threshold_uncertainty_score":0.8236238},"labels":[],"label_agreement":null},{"id":"W1974968077","doi":"10.1074/jbc.m000157200","title":"Dopamine D5 Receptor Agonist High Affinity and Constitutive Activity Profile Conferred by Carboxyl-terminal Tail Sequence","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Receptor; Agonist; Inverse agonist; Dopamine receptor D1; Biology; Mutant; Dopamine receptor; Affinities; 5-HT5A receptor; Endogenous agonist; Molecular biology; Cell biology; Biochemistry; Gene","score_opus":0.019465510795323424,"score_gpt":0.2502988406322204,"score_spread":0.23083332983689697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974968077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975472,0.00055735937,0.00014606971,0.00011561687,0.0000858112,0.00008256021,0.00015602537,0.000008046321,0.0013012816],"genre_scores_gemma":[0.99721366,0.00077513605,0.00081373536,0.00007717534,0.000347747,0.000005525133,0.000088502195,0.000009052155,0.00066947547],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988693,0.00007538963,0.00033431136,0.0003128138,0.00015039966,0.00025780086],"domain_scores_gemma":[0.9992094,0.00003378965,0.00026878619,0.00014619157,0.00013626849,0.00020556865],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00028009812,0.00022261553,0.0003435558,0.000010207385,0.00011160792,0.000044764864,0.00021345363,0.00034493313,0.0015407372],"category_scores_gemma":[0.00014124963,0.00016605358,0.00012021692,0.000051898434,0.00037670197,0.000010664196,0.00006073176,0.00031610206,0.000004475658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004562203,0.0001080911,0.00029667246,0.000018741453,0.00004806682,0.000028823397,0.000007654947,0.0000032264568,0.9926094,0.000006228868,0.0007367172,0.0056801843],"study_design_scores_gemma":[0.00065639714,0.0005267339,0.00015500173,0.00003151819,0.000018696559,0.00032041784,0.000048497186,0.000012602717,0.9863968,0.000045218934,0.011567255,0.00022085704],"about_ca_topic_score_codex":0.000013041394,"about_ca_topic_score_gemma":4.723065e-7,"teacher_disagreement_score":0.010830537,"about_ca_system_score_codex":0.0000311685,"about_ca_system_score_gemma":0.00012971804,"threshold_uncertainty_score":0.999372},"labels":[],"label_agreement":null},{"id":"W1974971773","doi":"10.1016/j.jaci.2006.11.646","title":"Internalization of CysLT1 Receptor Through the Clathrin Endocytic Pathway","year":2007,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Internalization; Dynamin; Clathrin; Cell biology; Endocytic cycle; Endocytosis; Endosome; Receptor; Transfection; G protein-coupled receptor; Biology; Chemistry; Signal transduction; Intracellular; Cell culture; Biochemistry","score_opus":0.019508644938336806,"score_gpt":0.3052839905307463,"score_spread":0.28577534559240947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1974971773","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93859506,0.005551694,0.05428907,0.00016001952,0.00095796084,0.00004795143,0.0000012825777,0.0000018667259,0.00039508252],"genre_scores_gemma":[0.98842067,0.009529883,0.0012122975,0.00026657188,0.0004073981,4.4742163e-7,0.0000041783187,0.000009947603,0.00014858118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865854,0.00014910116,0.00083430466,0.00011923222,0.00009349087,0.00014532346],"domain_scores_gemma":[0.9989343,0.00013326354,0.00056841725,0.00014799953,0.00017879104,0.000037202924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009602055,0.000091134825,0.000238167,0.000026155834,0.00004777517,0.000007810009,0.00021412708,0.00022602704,0.000107000575],"category_scores_gemma":[0.00026978014,0.000058798338,0.00018561125,0.000046533904,0.0001987483,0.000007585415,0.00008315644,0.0002497001,0.0000018733984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017417201,0.00025549362,0.00083129364,0.000007052236,0.0016091036,0.000014446769,0.00029017535,0.000041316784,0.950492,0.010260227,0.0004490205,0.03400813],"study_design_scores_gemma":[0.0031990737,0.006288863,0.0036309524,0.00011000107,0.000073101066,0.00035095756,0.0013580688,0.000028282084,0.7118174,0.0049874787,0.26790598,0.00024985324],"about_ca_topic_score_codex":0.000008119852,"about_ca_topic_score_gemma":0.000021591786,"teacher_disagreement_score":0.26745698,"about_ca_system_score_codex":0.0000068307118,"about_ca_system_score_gemma":0.000058598926,"threshold_uncertainty_score":0.23977266},"labels":[],"label_agreement":null},{"id":"W197505209","doi":"","title":"The use of integrated behavioral station in chronic behavioral studies","year":2008,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Water maze; Morris water navigation task; Psychology; Neuroscience; Open field; Behavioral analysis; Developmental psychology; Medicine; Cognition; Psychiatry; Hippocampus","score_opus":0.1142399268256768,"score_gpt":0.3416940989875927,"score_spread":0.22745417216191588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W197505209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998302,0.00079661235,0.0006833062,0.000013741281,0.00008152114,0.000102129874,0.000007437132,0.0000044929257,0.000008780208],"genre_scores_gemma":[0.9973502,0.0010085913,0.0008815055,0.000012887859,0.00002316639,0.000014140027,0.00005382379,0.000007575062,0.00064811],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946094,0.000038601014,0.00018337283,0.000120596545,0.00007543089,0.00012104136],"domain_scores_gemma":[0.9997003,0.00000932348,0.000049782677,0.00012595244,0.00009766385,0.00001694335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008029938,0.00007378265,0.0000890026,0.000022051108,0.00006713538,0.000007479901,0.00006650623,0.000054752516,0.000023592775],"category_scores_gemma":[0.000016034091,0.000048144026,0.000040426406,0.00006571859,0.00008162907,0.0000043579676,0.000034364868,0.000049430884,0.0000010743885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035259458,0.000051520146,0.0031157474,0.0000026511736,0.000012439127,0.0000027842827,0.00016645655,0.00022171055,0.9915031,0.00007963494,0.0005876347,0.0042210408],"study_design_scores_gemma":[0.0003827886,0.0007952413,0.0012527175,0.000012397398,0.000010901284,0.0000053759286,0.000805396,0.00020288293,0.98938626,0.0000227886,0.0070104427,0.00011282353],"about_ca_topic_score_codex":0.00037845355,"about_ca_topic_score_gemma":0.0010351863,"teacher_disagreement_score":0.006422808,"about_ca_system_score_codex":0.000035930458,"about_ca_system_score_gemma":0.000084406216,"threshold_uncertainty_score":0.19632564},"labels":[],"label_agreement":null},{"id":"W1975419193","doi":"10.1161/01.res.0000095452.77140.7a","title":"The Janus Faces of iNOS","year":2003,"lang":"en","type":"letter","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Janus; Chemistry; Medicine; Nanotechnology; Materials science","score_opus":0.07498549458582054,"score_gpt":0.3539366299789512,"score_spread":0.27895113539313066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975419193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5095399,0.023833204,0.007996272,0.412954,0.0033703574,0.0043288176,0.00016434271,0.000048399983,0.037764672],"genre_scores_gemma":[0.9083221,0.0017889026,0.00029453708,0.06060198,0.005174478,0.00022582359,0.0013914749,0.00017113432,0.022029549],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980953,0.00043763427,0.00024271559,0.0003001256,0.0005923179,0.00033192936],"domain_scores_gemma":[0.9988476,0.000102918544,0.00010133112,0.00047763728,0.00044103622,0.000029471477],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010751917,0.0001168917,0.0001321034,0.00008252155,0.00024456924,0.00006783411,0.00032781408,0.00056367164,0.00013302434],"category_scores_gemma":[0.00026147033,0.00008761171,0.00010789213,0.00014820497,0.0001558541,0.0000017572738,0.00007528436,0.0006880204,0.000022569335],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000098407645,0.000008433054,0.00028613384,0.000057955906,0.000064438565,0.0000049700516,0.000024356716,0.00014596325,0.211874,0.000103212944,0.7853654,0.0020553214],"study_design_scores_gemma":[0.000111758,0.0000678837,0.00015815585,0.000018155628,0.0000055722635,0.000004058915,0.00005685044,0.00006946753,0.0746069,0.00067861506,0.9241041,0.00011845564],"about_ca_topic_score_codex":0.000035910038,"about_ca_topic_score_gemma":0.0000067958163,"teacher_disagreement_score":0.3987822,"about_ca_system_score_codex":0.000018837702,"about_ca_system_score_gemma":0.00015972136,"threshold_uncertainty_score":0.43475518},"labels":[],"label_agreement":null},{"id":"W1975507912","doi":"10.1073/pnas.1011651107","title":"M <sub>3</sub> -muscarinic receptor promotes insulin release via receptor phosphorylation/arrestin-dependent activation of protein kinase D1","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Wellcome Trust; U.S. Department of Health and Human Services","keywords":"Interleukin-13 receptor; Muscarinic acetylcholine receptor M5; Muscarinic acetylcholine receptor M3; Cell biology; Phosphorylation; Enzyme-linked receptor; G protein-coupled receptor kinase; Arrestin; Biology; G protein-coupled receptor; Insulin receptor; 5-HT5A receptor; Chemistry; Receptor; Endocrinology; Muscarinic acetylcholine receptor; Signal transduction; Insulin-like growth factor 1 receptor; Biochemistry; Insulin; Insulin resistance","score_opus":0.015253281291421743,"score_gpt":0.2504899511059185,"score_spread":0.23523666981449673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975507912","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99864405,0.00007104189,0.00003211776,0.00047163817,0.0000615984,0.0004327567,0.000018745983,0.000007838693,0.00026021985],"genre_scores_gemma":[0.9956042,0.00002866945,0.0040401826,0.0000483319,0.00017277531,0.000035820343,0.0000032436246,0.000010374741,0.000056388864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99816716,0.000014579077,0.00045660243,0.00035513227,0.000841134,0.00016539166],"domain_scores_gemma":[0.9985797,0.0000341564,0.00075232284,0.000024935889,0.0005534398,0.000055438228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012652598,0.00014072622,0.0001666216,0.00010805605,0.0001586215,0.000019728723,0.0005731956,0.00021612032,0.000041087063],"category_scores_gemma":[0.0012233794,0.0001073729,0.00010342814,0.00040517483,0.00039666734,0.000051961775,0.00014956853,0.00023711912,0.0000019915503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008182051,0.00008571399,0.00041987415,0.000054837954,0.00001551887,1.6797425e-9,0.000059830858,0.000042541742,0.9938512,0.0021135032,0.000094984985,0.0031801998],"study_design_scores_gemma":[0.0002384196,0.00015355456,0.0013613175,0.00008964978,0.0000075586017,0.0000014304397,0.000052709445,0.00028433703,0.99205697,0.005476052,0.00015878146,0.00011920479],"about_ca_topic_score_codex":0.000009722489,"about_ca_topic_score_gemma":2.541753e-7,"teacher_disagreement_score":0.0040080645,"about_ca_system_score_codex":0.000016637161,"about_ca_system_score_gemma":0.000093791336,"threshold_uncertainty_score":0.437854},"labels":[],"label_agreement":null},{"id":"W1975574248","doi":"10.1111/j.1460-9568.2006.05085.x","title":"Activation of muscarinic cholinergic receptors inhibits giant neurones in the caudal pontine reticular nucleus","year":2006,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Oxotremorine; Muscarinic acetylcholine receptor; Neuroscience; Muscarinic acetylcholine receptor M2; Carbachol; Excitatory postsynaptic potential; Chemistry; Postsynaptic potential; Endocrinology; Inhibitory postsynaptic potential; Internal medicine; Biology; Receptor; Medicine; Stimulation","score_opus":0.012274973445942597,"score_gpt":0.2226570289484054,"score_spread":0.2103820555024628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975574248","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975778,0.00008721019,0.0011721383,0.00023423471,0.00036468424,0.00006256519,0.0000012667649,0.0000021847336,0.0004979162],"genre_scores_gemma":[0.99898326,0.00007355199,0.0003237191,0.00026588613,0.0002434134,3.1964714e-7,0.0000018249939,0.00001520297,0.00009283265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985013,0.00039767197,0.00045982946,0.00018473786,0.00029136823,0.00016510407],"domain_scores_gemma":[0.99928385,0.000015794658,0.0003889474,0.00018206812,0.0000926357,0.000036723588],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001023,0.000106695494,0.0001248002,0.00008609287,0.00005588115,0.00003490892,0.0004248355,0.000021820944,0.000006012096],"category_scores_gemma":[0.00021114845,0.000074113894,0.00009393408,0.0002568971,0.0000903366,0.000016752017,0.00006383843,0.00016800099,9.4827715e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033304044,0.000060818387,0.00015606015,0.0000038266726,9.249528e-7,0.000034652938,0.00006223393,0.0018127658,0.9969863,0.000044745597,0.0002142621,0.0005900771],"study_design_scores_gemma":[0.000652947,0.0010333891,0.063304774,0.000059596954,0.000009841999,0.00025035924,0.000099158315,0.00034428848,0.9226541,0.000036319056,0.011407983,0.00014724434],"about_ca_topic_score_codex":0.000006967261,"about_ca_topic_score_gemma":0.000001348684,"teacher_disagreement_score":0.07433223,"about_ca_system_score_codex":0.000005528286,"about_ca_system_score_gemma":0.000033695167,"threshold_uncertainty_score":0.30222768},"labels":[],"label_agreement":null},{"id":"W1975807362","doi":"10.1016/s0169-328x(00)00242-4","title":"Identification of four novel human G protein-coupled receptors expressed in the brain","year":2001,"lang":"en","type":"article","venue":"Molecular Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Biology; G protein-coupled receptor; Human brain; Complementary DNA; Thalamus; Putamen; Expressed sequence tag; Peptide sequence; Genetics; Molecular biology; Receptor; Gene; Neuroscience","score_opus":0.05043821609916982,"score_gpt":0.34944807206297746,"score_spread":0.29900985596380764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975807362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97822136,0.00014971226,0.01818466,0.0021410666,0.000037262605,0.0008340832,0.000005254733,0.000006919555,0.00041967412],"genre_scores_gemma":[0.9978603,0.0000143860725,0.00031579856,0.00021217205,0.00008507628,0.00020932798,0.00006634763,0.00003295148,0.0012036456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974107,0.0005949437,0.00040509604,0.0004570485,0.000695292,0.0004369304],"domain_scores_gemma":[0.99883705,0.00007674853,0.000100842895,0.0006848948,0.0002399746,0.000060487448],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0043498836,0.00014343439,0.00015335562,0.00019381061,0.00015765397,0.00007006276,0.0006847922,0.00017975236,0.000087986795],"category_scores_gemma":[0.00091726065,0.000120921664,0.00010918575,0.00053007266,0.00013394713,0.0000065656513,0.0001452047,0.00028867944,0.000008057487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055526492,0.0001331634,0.000069852584,0.000022932227,0.000018072413,0.000014061834,0.00018367427,0.000098511846,0.9964501,0.0015586736,0.00086363516,0.0005317628],"study_design_scores_gemma":[0.0006513498,0.0002469598,0.0002702944,0.000031962067,0.0000022839965,0.0000073463248,0.00038652352,0.0003412866,0.9907867,0.0010585117,0.0060780374,0.00013877646],"about_ca_topic_score_codex":0.00011177301,"about_ca_topic_score_gemma":0.000043231397,"teacher_disagreement_score":0.019638928,"about_ca_system_score_codex":0.000023119506,"about_ca_system_score_gemma":0.00008008866,"threshold_uncertainty_score":0.49310425},"labels":[],"label_agreement":null},{"id":"W1976149002","doi":"10.1038/nsmb1134","title":"Probing the activation-promoted structural rearrangements in preassembled receptor–G protein complexes","year":2006,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":454,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Heterotrimeric G protein; G protein; Conformational change; G beta-gamma complex; G protein-coupled receptor; Protein subunit; Chemistry; Förster resonance energy transfer; Biophysics; Receptor; Transmembrane domain; Protein structure; G alpha subunit; Transmembrane protein; Allosteric regulation; Biochemistry; Biology","score_opus":0.0048185158498758466,"score_gpt":0.2672378185925401,"score_spread":0.26241930274266423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976149002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99601424,0.00067465135,0.0011548277,0.00057107914,0.0002877196,0.0009951928,0.000023852408,0.000031107742,0.00024735363],"genre_scores_gemma":[0.99582213,0.000003880398,0.0023973563,0.0003114247,0.0003035436,0.000077177545,0.00090214587,0.00003954306,0.00014280896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99796486,0.00030684276,0.00038707737,0.00064593117,0.00018851532,0.0005067703],"domain_scores_gemma":[0.9991771,0.000012577913,0.00019893346,0.0004254721,0.0001357552,0.00005014847],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002157158,0.00034812067,0.00027248458,0.00009308042,0.0002031744,0.000056366596,0.00045983752,0.00064789265,0.00010678659],"category_scores_gemma":[0.00009856574,0.00024244521,0.00013685449,0.00026631946,0.00011229062,0.000011345066,0.00015539094,0.00057028345,0.000003085813],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011302914,0.000007983891,0.00071947114,0.000013186325,0.00004613914,0.0000026095333,0.00002613136,0.000150583,0.9909662,0.006812909,0.00013169304,0.0010100676],"study_design_scores_gemma":[0.00080747576,0.00017409676,0.0035122556,0.00003203835,0.000010744427,0.0000149742855,0.000036843994,0.00018460765,0.98416936,0.008759633,0.0019651486,0.00033282719],"about_ca_topic_score_codex":0.00023722205,"about_ca_topic_score_gemma":0.0000927389,"teacher_disagreement_score":0.006796842,"about_ca_system_score_codex":0.000049298684,"about_ca_system_score_gemma":0.00006091465,"threshold_uncertainty_score":0.98866284},"labels":[],"label_agreement":null},{"id":"W1976412816","doi":"10.1016/j.celrep.2013.10.015","title":"Select G-Protein-Coupled Receptors Modulate Agonist-Induced Signaling via a ROCK, LIMK, and β-Arrestin 1 Pathway","year":2013,"lang":"en","type":"article","venue":"Cell Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Jonsson Comprehensive Cancer Center; National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Cancer Institute; California NanoSystems Institute; National Institute of General Medical Sciences; National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Cell biology; Nociceptin receptor; Agonist; Receptor; Rho-associated protein kinase; Chemistry; Arrestin; Biology; Signal transduction; Biochemistry; Opioid; Opioid peptide","score_opus":0.007796368727383045,"score_gpt":0.19763231858871286,"score_spread":0.18983594986132982,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976412816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99258995,0.0005137353,0.0052340445,0.000030344798,0.00033036925,0.0007495922,8.6777396e-7,0.000045220357,0.0005058563],"genre_scores_gemma":[0.9958247,0.000026057562,0.0017450694,0.00008083448,0.00026915438,0.00015859035,0.0000657358,0.000063527936,0.0017663265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980657,0.00006435889,0.00048790994,0.0007213317,0.00020819291,0.00045249006],"domain_scores_gemma":[0.9988408,0.0000123118525,0.00030967285,0.00044194178,0.00015965172,0.00023563732],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033291162,0.0003054254,0.00027044833,0.0000542766,0.00019813316,0.00010743999,0.00010975102,0.00027355363,0.00039291577],"category_scores_gemma":[0.000086020686,0.00028589758,0.00012015027,0.00010939094,0.00002272768,0.000011788218,0.000116178795,0.00017435485,0.000027499756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013994228,0.000038878366,0.00018457812,0.000029765943,0.000024906249,0.00005251285,0.000049302886,0.00019011533,0.9968458,0.000003476807,0.00015309571,0.0024136137],"study_design_scores_gemma":[0.000222359,0.00027409973,0.00004798226,0.000036327136,0.000014094839,0.000108416265,0.00004158585,0.0018753607,0.9939479,0.00039012206,0.0026622629,0.00037945434],"about_ca_topic_score_codex":0.00018547088,"about_ca_topic_score_gemma":0.000006793755,"teacher_disagreement_score":0.0034889753,"about_ca_system_score_codex":0.00002032165,"about_ca_system_score_gemma":0.000102536906,"threshold_uncertainty_score":0.9999593},"labels":[],"label_agreement":null},{"id":"W1976833049","doi":"10.1038/sj.bjp.0703406","title":"Blockade of phencyclidine‐induced effects by a nitric oxide donor","year":2000,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Phencyclidine; Sodium nitroprusside; Pharmacology; Mechanism of action; Schizophrenia (object-oriented programming); Neuroscience; NMDA receptor; Nitric oxide; Psychotomimetic; Psychosis; Medicine; Chemistry; Psychology; Internal medicine; Receptor; Psychiatry; In vitro; Biochemistry","score_opus":0.004743314865965959,"score_gpt":0.24230188930239152,"score_spread":0.23755857443642556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976833049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99297565,0.0059951926,0.0003019261,0.000055737604,0.0002883127,0.000117215626,0.0000126042105,0.0000036344113,0.00024973945],"genre_scores_gemma":[0.99519867,0.0030258347,0.00055488985,0.00030990606,0.00049000554,0.0000052744535,0.000008373053,0.000020840687,0.0003862145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998821,0.00016677474,0.00045796315,0.0001656644,0.00014222748,0.00024632516],"domain_scores_gemma":[0.9993985,0.00003479561,0.00026907393,0.00005403055,0.00012898978,0.000114550814],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029618855,0.00012263852,0.00030379446,0.000055121218,0.000052988362,0.000013763078,0.000251031,0.00015255943,0.0012827814],"category_scores_gemma":[0.00004189198,0.00013789091,0.00018327082,0.00010147908,0.00004022537,0.000007380623,0.000028112514,0.00020855706,0.0000051381053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016014639,0.00016459575,0.00004485742,0.000024034382,0.00014129367,0.000110850786,0.000008220357,0.000040732713,0.9517048,0.0000011458644,0.017345142,0.030254198],"study_design_scores_gemma":[0.001971382,0.00052468485,0.00020102586,0.00004167486,0.00009498911,0.001275216,0.000010949389,0.000017757444,0.9833257,0.000041516003,0.012362996,0.00013207717],"about_ca_topic_score_codex":0.000036941437,"about_ca_topic_score_gemma":0.0000016641179,"teacher_disagreement_score":0.03162095,"about_ca_system_score_codex":0.000013260491,"about_ca_system_score_gemma":0.000074526026,"threshold_uncertainty_score":0.99963015},"labels":[],"label_agreement":null},{"id":"W1976879339","doi":"10.1093/bja/85.6.904","title":"Serotonergic receptor antagonists alter responses to general anaesthetics in rats","year":2000,"lang":"en","type":"article","venue":"British Journal of Anaesthesia","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Serotonergic; Chloral hydrate; Ketanserin; Pharmacology; Chemistry; Pentobarbital; Mianserin; Anesthesia; 5-HT receptor; Hypnotic; Ketamine; Medicine; Serotonin; Receptor; Biochemistry","score_opus":0.007850297271605527,"score_gpt":0.24465223302753974,"score_spread":0.23680193575593422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976879339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975327,0.0015720412,0.00013101826,0.00035813422,0.00011121836,0.00013163539,0.000008163988,0.000004504123,0.00015056737],"genre_scores_gemma":[0.9858006,0.004063431,0.0075417873,0.0009049073,0.00037126092,0.0000060747757,0.000011516626,0.00003829216,0.0012621122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854827,0.00018855373,0.0004993618,0.00023149142,0.00022487594,0.0003074667],"domain_scores_gemma":[0.9993907,0.0000049495634,0.00012441937,0.00016423584,0.00011426732,0.00020140033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005426145,0.00015330633,0.0002654208,0.000105638996,0.00007377214,0.00009519405,0.00028586524,0.00013613516,0.0003911453],"category_scores_gemma":[0.00003820764,0.00017121776,0.00014952105,0.00016083653,0.000037186433,0.000012679846,0.000023092533,0.00017359608,0.00002169115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011179408,0.00020862576,0.002459299,0.000010508626,0.000039735227,0.0011152842,0.00013608826,0.0012796912,0.68268734,0.00004338093,0.008399909,0.3025022],"study_design_scores_gemma":[0.002002425,0.0041497946,0.011451056,0.0004477644,0.000029005754,0.005010085,0.00014757247,0.00007484805,0.68287235,0.00022278418,0.29277092,0.00082137244],"about_ca_topic_score_codex":0.00007382009,"about_ca_topic_score_gemma":0.000050031093,"teacher_disagreement_score":0.3016808,"about_ca_system_score_codex":0.000027978327,"about_ca_system_score_gemma":0.000113907554,"threshold_uncertainty_score":0.69820577},"labels":[],"label_agreement":null},{"id":"W1976924764","doi":"10.1002/immu.200390023","title":"Mechanisms of H4/ICOS costimulation: effects on proximal TCR signals and MAP kinase pathways","year":2002,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"Ministerio de Ciencia y Tecnología; Instituto de Salud Carlos III; Associazione Italiana per la Ricerca sul Cancro; Comunidad de Madrid","keywords":"Biology; T-cell receptor; Cell biology; Signal transduction; Kinase; Immunology; T cell; Immune system","score_opus":0.013268252598994407,"score_gpt":0.20428200245819195,"score_spread":0.19101374985919753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976924764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97658616,0.0036384538,0.01838757,0.0001438166,0.0004262293,0.00013970585,0.0000048248007,0.0000056691374,0.00066755],"genre_scores_gemma":[0.99700946,0.0002397957,0.0022885385,0.00016529727,0.0001649213,9.708111e-7,0.0000045518423,0.000028285785,0.00009817187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986711,0.00044288114,0.00041326595,0.00016975634,0.00012458517,0.00017836984],"domain_scores_gemma":[0.99919254,0.000044879587,0.00038505354,0.00017593581,0.00013713697,0.00006443552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004996245,0.00015261745,0.0002498972,0.0000925007,0.000059894657,0.00001504766,0.00018633352,0.00006974311,0.00014516272],"category_scores_gemma":[0.00011518426,0.00012857006,0.000107298336,0.000045902656,0.000056891713,0.000006902064,0.00007386557,0.00017389866,0.000017563387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019478169,0.00007783618,0.000015970852,0.000020851208,0.00010134811,0.00009929859,0.00008456928,0.00009403856,0.9828631,0.00060079223,0.00022242367,0.015624971],"study_design_scores_gemma":[0.0015530833,0.0060894075,0.00048614983,0.000108839486,0.00003005934,0.000168253,0.000052286265,0.00010371491,0.98857677,0.00037825995,0.0023097778,0.00014340912],"about_ca_topic_score_codex":3.7481513e-7,"about_ca_topic_score_gemma":8.4575305e-8,"teacher_disagreement_score":0.020423286,"about_ca_system_score_codex":0.000008302926,"about_ca_system_score_gemma":0.000013618391,"threshold_uncertainty_score":0.5242935},"labels":[],"label_agreement":null},{"id":"W1977033769","doi":"10.1074/jbc.m314090200","title":"G Protein-coupled Receptor Kinase 2 Regulator of G Protein Signaling Homology Domain Binds to Both Metabotropic Glutamate Receptor 1a and Gαq to Attenuate Signaling","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"G protein-coupled receptor kinase; G protein-coupled receptor; Beta adrenergic receptor kinase; Regulator of G protein signaling; Biology; Metabotropic glutamate receptor 1; Heterotrimeric G protein; 5-HT5A receptor; Metabotropic glutamate receptor; Arrestin; G protein; Enzyme-linked receptor; Cell biology; Interleukin-13 receptor; Biochemistry; Metabotropic receptor; Signal transduction; Receptor; GTPase-activating protein; Agonist; Insulin-like growth factor 1 receptor","score_opus":0.011650088860913463,"score_gpt":0.23301222361211993,"score_spread":0.22136213475120647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977033769","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99191844,0.0009535705,0.0058472785,0.0005580469,0.00013459784,0.0005164746,0.000036457728,0.000014941341,0.000020175032],"genre_scores_gemma":[0.9516483,0.000054017382,0.04725649,0.00018368036,0.0006234481,0.00004461988,0.000022661216,0.00003885883,0.00012790912],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973868,0.0001287884,0.0010432535,0.00057712744,0.00032461932,0.000539412],"domain_scores_gemma":[0.99813634,0.000027547932,0.00066940725,0.00031938337,0.00034274414,0.0005045702],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009366835,0.0004060894,0.00077530293,0.00009270881,0.00012328461,0.00004615803,0.00045917556,0.00051074114,0.00026885953],"category_scores_gemma":[0.00041825417,0.00031229435,0.0003007344,0.00026468222,0.0001439939,0.000013845609,0.00023023458,0.00035082825,0.0000073669794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011215839,0.00014808546,0.00008052627,0.00009084701,0.00013205667,0.000024172385,0.000067110675,0.0004666374,0.99724066,0.000058093716,0.000030332209,0.0005398828],"study_design_scores_gemma":[0.0012905876,0.002326463,0.000037434515,0.0003515596,0.000028333121,0.00006939251,0.00017029356,0.0000031234647,0.992639,0.00057185086,0.0021228702,0.00038910087],"about_ca_topic_score_codex":0.000009552066,"about_ca_topic_score_gemma":6.6298304e-7,"teacher_disagreement_score":0.04140921,"about_ca_system_score_codex":0.00007586337,"about_ca_system_score_gemma":0.00017206519,"threshold_uncertainty_score":0.9999329},"labels":[],"label_agreement":null},{"id":"W1977234970","doi":"10.1074/jbc.m306589200","title":"Palmitoylation of the V2 Vasopressin Receptor Carboxyl Tail Enhances β-Arrestin Recruitment Leading to Efficient Receptor Endocytosis and ERK1/2 Activation","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Palmitoylation; Cell biology; G protein-coupled receptor kinase; G protein-coupled receptor; Arrestin; Protein kinase A; Biology; Endocytosis; Arginine vasopressin receptor 2; Enzyme-linked receptor; Tropomyosin receptor kinase C; Receptor; Chemistry; Biochemistry; Signal transduction; Phosphorylation; Cysteine","score_opus":0.036378002018883505,"score_gpt":0.27255368182457235,"score_spread":0.23617567980568885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977234970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972405,0.0005562028,0.0013975684,0.00012844816,0.00021996572,0.00016900068,0.000006666745,0.000003290157,0.00027838166],"genre_scores_gemma":[0.9968504,0.00019028902,0.0025403034,0.000057644484,0.00022323112,0.000012209088,0.0000071689965,0.000008838869,0.000109955094],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988411,0.000119522396,0.0004356188,0.00022734469,0.00019944008,0.00017695938],"domain_scores_gemma":[0.99906874,0.000058661863,0.00045390514,0.00015499597,0.00015846916,0.0001052473],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048859156,0.00015261715,0.00023483916,0.000020101734,0.00008547671,0.000021444277,0.00017823481,0.0001998249,0.00014354919],"category_scores_gemma":[0.0007748718,0.00009560027,0.00012937246,0.000115136776,0.000064920874,0.000004767402,0.00006152355,0.00016506677,9.710009e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009678074,0.00005495484,0.0010834248,0.00001953362,0.000033088007,2.693394e-7,0.000048930488,0.00030173964,0.99642956,0.000014431842,0.00020315741,0.0017141046],"study_design_scores_gemma":[0.0002784978,0.00023600787,0.00027828812,0.000113907015,0.000013503767,0.000011943291,0.00017514454,0.00000935341,0.9908051,0.000037076657,0.007922942,0.0001182602],"about_ca_topic_score_codex":0.0000017647636,"about_ca_topic_score_gemma":2.0057317e-7,"teacher_disagreement_score":0.0077197845,"about_ca_system_score_codex":0.000042385833,"about_ca_system_score_gemma":0.00006070108,"threshold_uncertainty_score":0.3898466},"labels":[],"label_agreement":null},{"id":"W1977303922","doi":"10.1016/j.lfs.2003.09.009","title":"Regulation of G protein-coupled receptor endocytosis and trafficking by Rab GTPases","year":2003,"lang":"en","type":"review","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":207,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"G protein-coupled receptor; Rab; Cell biology; GTPase; Endosome; Endocytosis; Heterotrimeric G protein; Biology; Rhodopsin-like receptors; G protein-coupled receptor kinase; Intracellular; G protein; Receptor; Signal transduction; Biochemistry","score_opus":0.030983727808075973,"score_gpt":0.29123469363723237,"score_spread":0.2602509658291564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977303922","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004528705,0.99433565,0.00034213485,0.000008827074,0.00014594152,0.00044166527,0.000025085554,0.0000070535266,0.00016494992],"genre_scores_gemma":[0.0018199676,0.99562776,0.0018299244,0.000021548358,0.000103822946,0.000049969243,0.00007655814,0.000017519962,0.00045292114],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985676,0.00012685728,0.0003947213,0.0004823084,0.00022273626,0.00020581363],"domain_scores_gemma":[0.99932104,0.0000269752,0.0003683075,0.00016120826,0.000042276242,0.00008017415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004999712,0.00022314678,0.0005465204,0.0000720468,0.00014391578,0.00003908771,0.00021936302,0.00020986391,0.000103827355],"category_scores_gemma":[0.0001481561,0.00017066277,0.00015622804,0.00021981238,0.0001954568,0.0000067415453,0.000048301063,0.000069644644,0.0000020199868],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010769598,0.00006124865,0.0000061404644,0.003286482,0.00011181626,2.8601016e-7,0.000038918497,0.000013362928,0.44949558,0.00039781007,0.001796944,0.5447806],"study_design_scores_gemma":[0.00011808498,0.00027627434,2.1280131e-7,0.0014468404,0.00007597451,0.000005256965,0.000047916623,0.000025846755,0.05229676,0.000020904938,0.94539833,0.00028761558],"about_ca_topic_score_codex":0.000010025474,"about_ca_topic_score_gemma":0.0000012450847,"teacher_disagreement_score":0.94360137,"about_ca_system_score_codex":0.000007719667,"about_ca_system_score_gemma":0.00021689077,"threshold_uncertainty_score":0.6959425},"labels":[],"label_agreement":null},{"id":"W1977484356","doi":"10.1038/nature12133","title":"Crystal structure of pre-activated arrestin p44","year":2013,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":170,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; University of New Brunswick","funders":"","keywords":"Arrestin; G protein-coupled receptor; Receptor; Cell biology; Chemistry; G protein; Biophysics; Biology; Biochemistry","score_opus":0.003690204550065212,"score_gpt":0.22411622479408724,"score_spread":0.22042602024402203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977484356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99843097,0.00053889916,0.00024275054,0.000057879486,0.00020001963,0.0001336839,0.000023025032,0.000008563556,0.00036423255],"genre_scores_gemma":[0.9977216,0.000010568714,0.001473554,0.0001709574,0.00017619824,0.0000030981012,0.00009243755,0.000014025571,0.0003375468],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946404,0.0000209232,0.0001053448,0.00017528028,0.00010598281,0.00012840581],"domain_scores_gemma":[0.99960285,0.0000048125503,0.00006385342,0.00017775447,0.00010616729,0.00004456097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000025776268,0.000097901066,0.00009755604,0.000019580737,0.000027018195,0.000012488869,0.00012716328,0.0008750365,0.00059709337],"category_scores_gemma":[0.00005857757,0.000078275116,0.000051282983,0.00005897041,0.000020562291,0.0000033220276,0.00004133668,0.00044127664,0.0000022782208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023360286,0.000010459847,0.00017981222,0.000011941024,0.000020757938,2.979027e-7,0.000021170039,0.00004259436,0.9961218,0.00009387616,0.0029142622,0.0005596483],"study_design_scores_gemma":[0.00016967059,0.00008383047,0.0017087853,0.000010749202,0.0000046586024,0.0000044718754,0.000025198146,0.000024845876,0.9913042,0.0004300667,0.0061394367,0.00009403921],"about_ca_topic_score_codex":0.000021065416,"about_ca_topic_score_gemma":0.0000046275163,"teacher_disagreement_score":0.004817572,"about_ca_system_score_codex":0.0000039318193,"about_ca_system_score_gemma":0.000028629727,"threshold_uncertainty_score":0.6749083},"labels":[],"label_agreement":null},{"id":"W1977649999","doi":"10.1074/jbc.m300573200","title":"A β-Arrestin-dependent Scaffold Is Associated with Prolonged MAPK Activation in Pseudopodia during Protease-activated Receptor-2-induced Chemotaxis","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":201,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of General Medical Sciences","keywords":"Pseudopodia; Cell biology; Chemotaxis; Biology; Cytoskeleton; Motility; Arrestin; Signal transduction; Actin cytoskeleton; Receptor; MAPK/ERK pathway; Actin; G protein-coupled receptor; Cell; Biochemistry","score_opus":0.019083813861273797,"score_gpt":0.230322639109515,"score_spread":0.2112388252482412,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1977649999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992148,0.00008036781,0.00008275284,0.000074464115,0.000053348755,0.0002240953,0.0000055473934,0.000011895264,0.00025271156],"genre_scores_gemma":[0.9990245,0.000039401162,0.0005291358,0.0000639204,0.00013953281,0.000020000734,0.000026639293,0.000023253144,0.00013359055],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998351,0.00013343939,0.0005190448,0.00036485936,0.00027541746,0.00035626342],"domain_scores_gemma":[0.99880177,0.000030570707,0.00059574994,0.00018658805,0.00022981456,0.0001555095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054844224,0.0002662063,0.0003672927,0.000043013035,0.00007869913,0.000034194774,0.00021245271,0.00047963,0.00031153168],"category_scores_gemma":[0.00086554914,0.00019404966,0.0001334793,0.0002054066,0.000046077395,0.000014673737,0.000040154795,0.00041980483,0.0000017148565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005878428,0.00024257824,0.0049897213,0.000022880798,0.00009236688,0.000022166494,0.00003639526,0.000018559367,0.9938291,0.0000015381247,0.0000316654,0.00012520699],"study_design_scores_gemma":[0.0017313461,0.0004949755,0.002261816,0.00016427394,0.000011290313,0.00008955093,0.00013938303,0.000003838767,0.9946744,0.000043125525,0.00012107739,0.0002649597],"about_ca_topic_score_codex":0.000003910316,"about_ca_topic_score_gemma":7.970234e-7,"teacher_disagreement_score":0.0027279053,"about_ca_system_score_codex":0.00012233233,"about_ca_system_score_gemma":0.0001526143,"threshold_uncertainty_score":0.79131156},"labels":[],"label_agreement":null},{"id":"W1978062162","doi":"10.1523/jneurosci.2656-12.2013","title":"Peptide Inhibitors Disrupt the Serotonin 5-HT<sub>2C</sub>Receptor Interaction with Phosphatase and Tensin Homolog to Allosterically Modulate Cellular Signaling and Behavior","year":2013,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; Klarman Family Foundation; Foundation for Prader-Willi Research","keywords":"Tensin; Phosphatase; 5-HT receptor; Allosteric regulation; Serotonin; Chemistry; Receptor; Signaling proteins; Cell biology; Signal transduction; Neuroscience; Biochemistry; Biology; Enzyme; PTEN; PI3K/AKT/mTOR pathway","score_opus":0.008902983372053787,"score_gpt":0.22286181286897494,"score_spread":0.21395882949692116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978062162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962844,0.00017254245,0.0026085526,0.00036733775,0.00028953867,0.00026775216,0.0000037606214,0.0000033952388,0.0000026900339],"genre_scores_gemma":[0.99787897,0.00009248877,0.0012099145,0.0006481098,0.00011566649,0.000012398743,0.0000014842552,0.00001529944,0.000025654506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989511,0.00006839039,0.000273437,0.00027462264,0.00022263528,0.00020983403],"domain_scores_gemma":[0.9992762,0.000020664724,0.00022711644,0.00013814347,0.00014548637,0.00019236542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025835173,0.00015009315,0.0001516661,0.000053377844,0.00016277315,0.00017080424,0.00016824297,0.000052804327,0.0000065227177],"category_scores_gemma":[0.000079141384,0.000093883624,0.000045466975,0.00011462119,0.00012575385,0.00004611907,0.0001181887,0.00017628084,0.0000018149667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053726508,0.000037306625,0.00075922225,0.000004590176,0.0000039408146,0.00002123952,0.00008088015,0.0002535332,0.99623466,0.0000020138766,0.00011489609,0.0024339922],"study_design_scores_gemma":[0.00022609282,0.0012374284,0.004435771,0.000043256758,0.00002417924,0.00037996925,0.00014784872,0.00033673586,0.9925443,0.0000091648835,0.0004816163,0.00013363696],"about_ca_topic_score_codex":0.000011397203,"about_ca_topic_score_gemma":0.0000020344346,"teacher_disagreement_score":0.0036903587,"about_ca_system_score_codex":0.00001097104,"about_ca_system_score_gemma":0.000033830573,"threshold_uncertainty_score":0.3828463},"labels":[],"label_agreement":null},{"id":"W1978354740","doi":"10.1021/jp002244b","title":"Probing the Origins of Spectroscopic Responses to Analyte-Induced Conformational Changes in Fluorescently-Labeled Cod III Parvalbumin","year":2000,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Analyte; Chemistry; Fluorescence; Absorbance; Conformational change; Biophysics; Biosensor; Analytical Chemistry (journal); Photochemistry; Chromatography; Stereochemistry; Biochemistry","score_opus":0.011637881803359743,"score_gpt":0.2648098009693465,"score_spread":0.25317191916598675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978354740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990998,0.000061920604,0.000050951,0.00042551916,0.0000211794,0.00012494418,0.000005216031,0.0000016625564,0.00020881474],"genre_scores_gemma":[0.99919426,0.000041405252,0.00005406228,0.000079089165,0.0003870683,0.0000046204354,0.0000057658594,0.000008270419,0.00022546214],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991573,0.00007143855,0.0002818947,0.00008609023,0.00023181191,0.00017148042],"domain_scores_gemma":[0.9994292,0.00005655237,0.00018448645,0.00018054678,0.000090228736,0.000058946473],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042018297,0.00011514347,0.00020299802,0.000018574712,0.00005633344,0.000014224088,0.00032766667,0.00005020517,0.00016418101],"category_scores_gemma":[0.00005175368,0.00006712094,0.00008745788,0.0001306936,0.00004654111,0.0000059525955,0.000035575387,0.00018484466,0.0000035787295],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050595583,0.000072519826,0.000027276827,0.0000155769,0.00003831075,0.0000011923559,0.00042410666,0.00030197826,0.9980067,0.000040824492,0.0000648361,0.0005007467],"study_design_scores_gemma":[0.00052425807,0.00025359253,0.00016079302,0.000060104092,0.000026525333,0.000014720242,0.0002323974,0.00022697255,0.99727273,0.000059676193,0.0010907215,0.00007751219],"about_ca_topic_score_codex":0.000011333864,"about_ca_topic_score_gemma":0.000004481035,"teacher_disagreement_score":0.0010258855,"about_ca_system_score_codex":0.000038007503,"about_ca_system_score_gemma":0.00009799283,"threshold_uncertainty_score":0.27371126},"labels":[],"label_agreement":null},{"id":"W1978542092","doi":"10.1161/01.res.0000109413.57726.91","title":"Agonist-Induced Activation of Matrix Metalloproteinase-7 Promotes Vasoconstriction Through the Epidermal Growth Factor–Receptor Pathway","year":2003,"lang":"en","type":"article","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Vasoconstriction; Angiotensin II; Endocrinology; Internal medicine; Mesenteric arteries; Epidermal growth factor receptor; Epidermal growth factor; Chemistry; Receptor; Biology; Medicine","score_opus":0.06731733643844455,"score_gpt":0.3361278090158582,"score_spread":0.26881047257741364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978542092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784196,0.00017237717,0.01925394,0.00018996763,0.00010586027,0.001032996,0.000009701622,0.000013616698,0.00080191676],"genre_scores_gemma":[0.9987275,0.000032356977,0.00073666446,0.000016892523,0.00012468442,0.00013351625,0.000077805285,0.000022618648,0.00012796752],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979758,0.0006063032,0.00029904305,0.000329561,0.0004935299,0.00029574338],"domain_scores_gemma":[0.99885416,0.00008704625,0.00014009801,0.00030846905,0.0005587727,0.000051448074],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009407529,0.00013109398,0.00013925342,0.00007989544,0.0003384384,0.000057690264,0.00016692423,0.00019241238,0.0002815454],"category_scores_gemma":[0.0007280661,0.00010279087,0.000116558134,0.00037280936,0.00008962927,0.000024749508,0.000043031036,0.0002197877,0.000014192672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015330206,0.000056191995,0.00083830673,0.00002773691,0.00004348482,2.0778813e-7,0.00013997099,0.00016158076,0.9893246,0.007912398,0.000056158246,0.001424029],"study_design_scores_gemma":[0.00027345857,0.00014297594,0.0010755011,0.000017002172,0.000004896099,0.0000030683382,0.0002941809,0.00017259104,0.99366057,0.001652664,0.0025877173,0.00011537659],"about_ca_topic_score_codex":0.000114191185,"about_ca_topic_score_gemma":0.0000034237255,"teacher_disagreement_score":0.020307869,"about_ca_system_score_codex":0.000042362284,"about_ca_system_score_gemma":0.00019988575,"threshold_uncertainty_score":0.419169},"labels":[],"label_agreement":null},{"id":"W1978552193","doi":"10.1139/y06-068","title":"M<sub>3</sub> muscarinic receptor-deficient mice retain bethanechol-mediated intestinal ion transport and are more sensitive to colitis","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Bethanechol; Muscarinic acetylcholine receptor; Endocrinology; Internal medicine; Ussing chamber; Muscarinic acetylcholine receptor M3; Pirenzepine; Muscarinic acetylcholine receptor M1; Agonist; Oxotremorine; Muscarinic acetylcholine receptor M4; Chemistry; Receptor; Acetylcholine; Ileum; Biology; Medicine","score_opus":0.006991678967953723,"score_gpt":0.2241798037150995,"score_spread":0.21718812474714577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978552193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99787855,0.0005269776,0.00017131535,0.00064636,0.00050055236,0.00015266093,0.00008481167,0.0000034355764,0.000035327914],"genre_scores_gemma":[0.99787164,0.00013690509,0.00014644118,0.001171419,0.0005384065,0.000005895884,0.00008639648,0.000017501661,0.000025404861],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987779,0.00017510814,0.000319221,0.00029225217,0.000058527403,0.00037695537],"domain_scores_gemma":[0.99902177,0.00005108014,0.00019931683,0.00006778696,0.00022187683,0.0004381701],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002915117,0.00018425571,0.0003083257,0.00015694834,0.00014580942,0.000008301456,0.00010520306,0.00022861868,0.000095449126],"category_scores_gemma":[0.00003701497,0.00018247055,0.000072969,0.00010229594,0.00021433593,0.000007818997,0.000020530504,0.00027653624,0.0000030421666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023850995,0.000018442177,0.0011654978,0.000024012254,0.00005837238,0.000086372806,0.0001303752,0.00017902577,0.99577457,0.0000292428,0.0019547343,0.0003408401],"study_design_scores_gemma":[0.0007589093,0.00063385663,0.023894021,0.000031754185,0.00006291885,0.00030464618,0.00019301302,0.000031953055,0.96993905,0.00009147192,0.0038589917,0.00019943363],"about_ca_topic_score_codex":0.00046473817,"about_ca_topic_score_gemma":0.0018900757,"teacher_disagreement_score":0.025835544,"about_ca_system_score_codex":0.000036534424,"about_ca_system_score_gemma":0.00028214563,"threshold_uncertainty_score":0.74409336},"labels":[],"label_agreement":null},{"id":"W1978677632","doi":"10.1023/b:mcbi.0000041844.24424.35","title":"Changes in beta-adrenoceptors in heart failure due to myocardial infarction are attenuated by blockade of renin-angiotensin system.","year":2004,"lang":"en","type":"article","venue":"PubMed","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Internal medicine; Heart failure; Enalapril; Inotrope; Medicine; Losartan; ACE inhibitor; Ramipril; Angiotensin-converting enzyme; Cardiology; Endocrinology; Myocardial infarction; Angiotensin II; Receptor; Blood pressure","score_opus":0.008513437789737417,"score_gpt":0.19770066320122473,"score_spread":0.1891872254114873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978677632","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961223,0.00022534425,0.00013875306,0.0026466262,0.00020977238,0.00058459345,0.000034565775,0.000013703474,0.000024345243],"genre_scores_gemma":[0.9988406,0.000009014848,0.00036339712,0.00016769426,0.00018719547,0.00029110364,0.00007571378,0.000023173761,0.00004216024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880254,0.00007306975,0.00027380887,0.00034026484,0.00015756558,0.0003527721],"domain_scores_gemma":[0.9995345,0.0000058406295,0.000095691525,0.00019805784,0.000063668864,0.00010225745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032955737,0.00015645403,0.00031335693,0.00014955229,0.000024954026,0.000014479357,0.00010876891,0.0002207244,0.0000063399066],"category_scores_gemma":[0.000054277996,0.00015728522,0.00008120638,0.0002786489,0.000021532174,0.0000042193647,0.00005563654,0.00010012024,0.0000029452158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095898664,0.000055257828,0.0110531645,0.000019531793,0.0000522832,0.0000057973857,0.000112134076,0.0009947271,0.9837523,0.000016090691,0.002320811,0.0015219856],"study_design_scores_gemma":[0.00081654056,0.00008643852,0.07095417,0.00004631076,0.00001453053,0.00001329059,0.00019235497,0.0000040250666,0.9222537,0.000009879112,0.005409853,0.00019885333],"about_ca_topic_score_codex":0.00040635982,"about_ca_topic_score_gemma":0.0011340921,"teacher_disagreement_score":0.061498564,"about_ca_system_score_codex":0.00007663519,"about_ca_system_score_gemma":0.000024123281,"threshold_uncertainty_score":0.64139056},"labels":[],"label_agreement":null},{"id":"W1978809815","doi":"10.1111/j.1471-4159.2007.04650.x","title":"Differential signaling of dopamine‐D<sub>2</sub>S and ‐D<sub>2</sub>L receptors to inhibit ERK1/2 phosphorylation","year":2007,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Phosphorylation; Agonist; Biology; Protein kinase C; Dopamine receptor; Signal transduction; Kinase; Molecular biology; Cell biology; Chemistry; Biochemistry","score_opus":0.0066655402302303315,"score_gpt":0.21932098676261355,"score_spread":0.21265544653238322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978809815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98337686,0.00038844004,0.015600429,0.000042572716,0.00042096412,0.00010608563,0.0000064657843,0.00000767486,0.00005050809],"genre_scores_gemma":[0.9981713,0.0003024404,0.0005871587,0.00009713605,0.0007538431,0.0000017878647,0.000018701145,0.000044874807,0.000022752916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99804693,0.00003906332,0.0008279283,0.00034421493,0.00040695193,0.00033491437],"domain_scores_gemma":[0.99846053,0.000051612464,0.0006180761,0.00021708167,0.0003500261,0.00030265175],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043238373,0.0002761603,0.00036760763,0.00011479271,0.0000828999,0.000040360635,0.00022225118,0.00025979985,0.000023026863],"category_scores_gemma":[0.00024481912,0.00026972184,0.00021483448,0.0001714285,0.000060590897,0.00001547288,0.0001234464,0.0003114798,0.0000016794072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042865647,0.00008112492,0.00029303064,0.000067126435,0.000060155424,0.000017204102,0.00006260536,0.00013094168,0.9887531,0.0000029144492,0.00028676036,0.009816421],"study_design_scores_gemma":[0.0006753294,0.00047232883,0.00052905723,0.00012312602,0.000057284065,0.00015973931,0.0001278992,0.000021450882,0.99696636,0.000030714167,0.0005826039,0.0002541046],"about_ca_topic_score_codex":0.0000012009466,"about_ca_topic_score_gemma":0.0000014297931,"teacher_disagreement_score":0.01501327,"about_ca_system_score_codex":0.000030156189,"about_ca_system_score_gemma":0.0000785886,"threshold_uncertainty_score":0.9999755},"labels":[],"label_agreement":null},{"id":"W19789852","doi":"10.1023/a:1014845300488","title":"Alterations of cardiac β-adrenoceptor mechanisms due to calcium depletion and repletion","year":2002,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Calcium; Clinical chemistry; Endocrinology; Internal medicine; Chemistry; Medicine; Cell biology; Biology","score_opus":0.007822102565329796,"score_gpt":0.20603234465478795,"score_spread":0.19821024208945814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W19789852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8898463,0.0028886206,0.10645691,0.00015330019,0.000085845364,0.00017955386,0.000035242276,0.000012426521,0.00034175295],"genre_scores_gemma":[0.9951965,0.000053348445,0.0039418875,0.0001764644,0.00009150673,0.000026646834,0.00020451506,0.00002750233,0.00028162825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988807,0.000046786146,0.0002281744,0.00045630714,0.00015741281,0.00023062425],"domain_scores_gemma":[0.99934703,0.000005338106,0.00007041586,0.00031147405,0.000079612175,0.00018614765],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001567197,0.00018761375,0.00019960343,0.000039232804,0.00009147743,0.00003379535,0.000087292836,0.00019442904,0.00010636246],"category_scores_gemma":[0.000045418426,0.00020136636,0.0000945983,0.00008511085,0.000047681573,0.0000037628226,0.00010044849,0.000072788185,0.0000027855026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020455192,0.000029814073,0.000023020586,0.00004531093,0.000036771784,0.000004284029,0.000032201347,0.000007941967,0.9978657,0.00039542888,0.0002868021,0.0012522732],"study_design_scores_gemma":[0.00027756812,0.00016215898,0.0000070027636,0.00002149625,0.000033006814,0.00002065466,0.00008161083,0.00011669998,0.9975613,0.00018047469,0.0013134643,0.00022458809],"about_ca_topic_score_codex":0.000011951787,"about_ca_topic_score_gemma":4.1842955e-7,"teacher_disagreement_score":0.10535015,"about_ca_system_score_codex":0.0000105139725,"about_ca_system_score_gemma":0.000012621332,"threshold_uncertainty_score":0.8211482},"labels":[],"label_agreement":null},{"id":"W1979104282","doi":"10.1097/00004647-200209000-00011","title":"<i>In Vivo</i> Receptor Assay with Multiple Ligand Concentrations: An Equilibrium Approach","year":2002,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; TRIUMF","funders":"","keywords":"Ligand (biochemistry); Raclopride; Chemistry; Receptor; In vivo; Biophysics; Dopamine receptor D2; Biochemistry; Biology","score_opus":0.01054654448379262,"score_gpt":0.21237321464183076,"score_spread":0.20182667015803815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979104282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99030197,0.0051299506,0.0031513313,0.00015429019,0.0005165836,0.00019096419,0.000025696538,0.000007163029,0.0005220656],"genre_scores_gemma":[0.96129006,0.00038795607,0.03573877,0.0003760844,0.0016090804,0.000008422303,0.000016803504,0.00004250254,0.000530313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983149,0.00018160044,0.000535927,0.0002877967,0.00033480386,0.00034495845],"domain_scores_gemma":[0.99899316,0.000018587685,0.00031742832,0.0002539609,0.00019933938,0.00021752529],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004632438,0.00023326807,0.00040440357,0.00009066864,0.000060036575,0.000084482665,0.00029050154,0.00017978404,0.00033585262],"category_scores_gemma":[0.00008216892,0.00017853522,0.00015840847,0.00016492695,0.000053843705,0.00007102816,0.000035004487,0.00025991767,0.0000039837964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013660615,0.0004505354,0.00068155903,0.000011571743,0.0001316474,0.00001127364,0.0002779991,0.00082715007,0.9950338,0.00011069121,0.0018051232,0.0005220143],"study_design_scores_gemma":[0.0035410246,0.00057077495,0.00006373569,0.00002875061,0.000120652236,0.00020102301,0.00020811867,0.0024461993,0.97098285,0.00005073872,0.021498531,0.00028757515],"about_ca_topic_score_codex":0.000007838475,"about_ca_topic_score_gemma":0.000008488114,"teacher_disagreement_score":0.03258744,"about_ca_system_score_codex":0.000008535454,"about_ca_system_score_gemma":0.000061132676,"threshold_uncertainty_score":0.7280455},"labels":[],"label_agreement":null},{"id":"W1979240985","doi":"10.1523/jneurosci.3065-04.2004","title":"Cortical GABA Interneurons in Neurovascular Coupling: Relays for Subcortical Vasoactive Pathways","year":2004,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":576,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Centre National de la Recherche Scientifique","keywords":"Vasoactive intestinal peptide; Biocytin; Neuroscience; Biology; Vasomotor; Cholinergic; Interneuron; Serotonergic; Neuropeptide; Anatomy; Chemistry; Electrophysiology; Endocrinology; Serotonin; Receptor; Inhibitory postsynaptic potential","score_opus":0.02753468753194945,"score_gpt":0.27028523110842917,"score_spread":0.2427505435764797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979240985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9148974,0.000075229,0.084089376,0.00014315486,0.0006228195,0.00014753977,0.0000035636829,0.000003184331,0.000017730983],"genre_scores_gemma":[0.9981869,0.0001308162,0.0011435502,0.000360892,0.00014414062,0.000005900649,8.221247e-7,0.000016384562,0.000010622468],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876446,0.000031696065,0.0003986882,0.00027793364,0.00025068095,0.00027656066],"domain_scores_gemma":[0.99938095,0.000036952933,0.00016379813,0.00015589633,0.00011787892,0.00014455312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041165072,0.00012016723,0.00018499246,0.00008040872,0.00006924231,0.00003956199,0.0003099829,0.00007427666,0.000002864878],"category_scores_gemma":[0.0006090048,0.000103143066,0.00019384363,0.00013576577,0.00010152978,0.000016619748,0.00006773657,0.00026098732,8.5484123e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010932044,0.00012599716,0.00044013892,0.0000045236134,0.0000039550105,0.00006982442,0.00003244659,0.005668202,0.99287236,0.0005610315,0.000012202454,0.00010001552],"study_design_scores_gemma":[0.0022394634,0.0042568385,0.013475221,0.000059252332,0.000044412827,0.0006974553,0.00011132269,0.0043194396,0.97136235,0.0010507813,0.0021079213,0.00027553292],"about_ca_topic_score_codex":0.0000014070717,"about_ca_topic_score_gemma":0.0000027115868,"teacher_disagreement_score":0.083289474,"about_ca_system_score_codex":0.000025733143,"about_ca_system_score_gemma":0.00016938851,"threshold_uncertainty_score":0.42060524},"labels":[],"label_agreement":null},{"id":"W1979400849","doi":"10.1111/dom.12442","title":"<scp>GPR40</scp> agonists for the treatment of type 2 diabetes: life after ‘TAKing’ a hit","year":2015,"lang":"en","type":"review","venue":"Diabetes Obesity and Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Canadian Diabetes Association","keywords":"Free fatty acid receptor 1; Medicine; Type 2 diabetes; Agonist; Clinical trial; Receptor; Diabetes mellitus; Pharmacology; Bioinformatics; Internal medicine; Endocrinology; Biology","score_opus":0.031152300544292563,"score_gpt":0.2842922124606352,"score_spread":0.2531399119163426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979400849","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.059492026,0.9384189,0.000038541257,0.0000063975926,0.00071074674,0.0009880182,0.00028074268,0.000011353663,0.00005326286],"genre_scores_gemma":[0.0021754962,0.99493784,0.00031435658,0.000104820436,0.00093990867,0.00044492458,0.0003679062,0.00006841182,0.0006463184],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982298,0.0001423789,0.00044991696,0.0005301496,0.00017384606,0.00047390864],"domain_scores_gemma":[0.99847466,0.00015941172,0.00043981272,0.00051726494,0.00020559916,0.00020323883],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004353914,0.00050770165,0.0014913543,0.00007496983,0.0001276391,0.00006945914,0.00028365845,0.00048577916,0.000017551316],"category_scores_gemma":[0.0002627526,0.00032219483,0.00063971616,0.0001358803,0.00011191635,0.0000061589435,0.000096870455,0.000105802654,0.0000068197364],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019043431,0.00054775336,0.00041215436,0.006212295,0.002944932,0.000001622592,0.00041419434,0.000003826597,0.0014250621,0.0002574681,0.0025728587,0.9851888],"study_design_scores_gemma":[0.0003970959,0.00035224095,0.00008956397,0.00036763662,0.0018364742,5.366856e-7,0.000021718737,0.0000118686,0.0027246266,0.00008069903,0.9939442,0.00017331346],"about_ca_topic_score_codex":0.0000065589447,"about_ca_topic_score_gemma":0.0000029947855,"teacher_disagreement_score":0.9913714,"about_ca_system_score_codex":0.000017805052,"about_ca_system_score_gemma":0.00023684178,"threshold_uncertainty_score":0.999923},"labels":[],"label_agreement":null},{"id":"W1979425616","doi":"10.1074/jbc.m407965200","title":"Analysis of the Third Transmembrane Domain of the Human Type 1 Angiotensin II Receptor by Cysteine Scanning Mutagenesis","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Mutagenesis; Cysteine; Transmembrane domain; Angiotensin II; Transmembrane protein; Receptor; Domain (mathematical analysis); Chemistry; Cell biology; Biology; Biochemistry; Mutation; Gene; Mathematics","score_opus":0.011850463875744635,"score_gpt":0.23530489203285077,"score_spread":0.22345442815710614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979425616","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99782187,0.0013298758,0.0002653962,0.00028788132,0.00008899551,0.00005484223,0.000032767723,0.000002115372,0.000116269184],"genre_scores_gemma":[0.9990192,0.00011636694,0.00048616863,0.00008156946,0.00012607868,6.880115e-7,0.00002019577,0.000008046191,0.00014170192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988355,0.000070862814,0.00054739433,0.00016906588,0.00021912946,0.0001580202],"domain_scores_gemma":[0.99885464,0.00001500671,0.0005886115,0.0002742706,0.00020753863,0.000059934795],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040794958,0.0001460756,0.0003919893,0.000022519725,0.000120103425,0.000006573001,0.00048065177,0.00026554955,0.000115928706],"category_scores_gemma":[0.000100533674,0.00007438116,0.0006486439,0.00038913143,0.00017953441,0.0000029550058,0.00010042159,0.00017873001,1.2484287e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007467587,0.000087243156,0.0012960484,0.000015817179,0.00045242676,8.8737306e-7,0.000048841976,0.0007425565,0.99702835,0.000008374076,0.00017274705,0.00007202159],"study_design_scores_gemma":[0.00043126193,0.00027911091,0.0009170186,0.000058244455,0.00020638543,0.000015495289,0.00010462755,0.0000033170572,0.99661297,0.00006529699,0.0012112415,0.00009502967],"about_ca_topic_score_codex":0.000009043519,"about_ca_topic_score_gemma":0.0000014220437,"teacher_disagreement_score":0.0012135089,"about_ca_system_score_codex":0.00002213839,"about_ca_system_score_gemma":0.00006579298,"threshold_uncertainty_score":0.30331758},"labels":[],"label_agreement":null},{"id":"W1979581007","doi":"10.1016/j.lfs.2006.08.024","title":"Influence of the antipsychotic drug pipamperone on the expression of the dopamine D4 receptor","year":2006,"lang":"en","type":"article","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research; Vlaamse regering","keywords":"5-HT5A receptor; Dopamine receptor D2; Biology; Dopamine receptor D1; Enzyme-linked receptor; Dopamine receptor; Receptor expression; Interleukin-21 receptor; Dopamine; Dopamine receptor D3; Receptor; Protease-activated receptor 2; Endogenous agonist; 5-HT6 receptor; Cell biology; 5-HT receptor; Serotonin; Biochemistry; Endocrinology","score_opus":0.008560111878063612,"score_gpt":0.22429392746607024,"score_spread":0.21573381558800664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979581007","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980991,0.0002789462,0.00003283749,0.0006813068,0.00020823957,0.00012762299,0.0000054788934,0.000002150874,0.000564315],"genre_scores_gemma":[0.99907154,0.000035328874,0.00012767604,0.00024003968,0.000085335196,0.0000044173366,7.284847e-7,0.0000036882932,0.0004312324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912065,0.00010392981,0.00017831854,0.00018218046,0.00028894178,0.00012597025],"domain_scores_gemma":[0.9994103,0.000038468028,0.00016756679,0.00032152396,0.000044618624,0.000017568054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043256505,0.0000770974,0.00007814409,0.000012602184,0.00022130401,0.000010969193,0.00066016236,0.000037383066,0.000034833392],"category_scores_gemma":[0.0001310104,0.000030803934,0.00007139674,0.00021017299,0.0004273242,0.000004339884,0.00010649693,0.000058135574,0.0000016121382],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009231701,0.000023839293,0.0025813645,0.0000041032554,0.0000017534838,1.1869692e-8,0.000039194016,0.002350101,0.9933859,0.0005774528,0.0009786803,0.0000483752],"study_design_scores_gemma":[0.000073331255,0.00006196404,0.006200423,0.0000635494,0.0000029148994,3.9684082e-7,0.00014049484,0.000026053283,0.99161834,0.0002720996,0.0014930873,0.000047324334],"about_ca_topic_score_codex":0.000049061935,"about_ca_topic_score_gemma":0.000007907921,"teacher_disagreement_score":0.0036190585,"about_ca_system_score_codex":0.0000023104353,"about_ca_system_score_gemma":0.000048786973,"threshold_uncertainty_score":0.17021139},"labels":[],"label_agreement":null},{"id":"W1979670456","doi":"10.1074/jbc.m109.077180","title":"Analysis of Transmembrane Domains 1 and 4 of the Human Angiotensin II AT1 Receptor by Cysteine-scanning Mutagenesis","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Transmembrane domain; Cysteine; Mutant; Receptor; Transmembrane protein; Mutagenesis; Angiotensin II; Chemistry; Biochemistry; Context (archaeology); Molecular biology; Biology; Enzyme; Gene","score_opus":0.010598472327416147,"score_gpt":0.23744655675988938,"score_spread":0.22684808443247323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979670456","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99758846,0.0016869275,0.00035243086,0.00017574157,0.000026071035,0.00004001685,0.000039782975,0.0000018642679,0.00008870101],"genre_scores_gemma":[0.9989431,0.00023173846,0.0005168917,0.00007268822,0.000097112956,4.059367e-7,0.000025197787,0.000005102409,0.00010775218],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989589,0.000051607592,0.00051976426,0.00017107878,0.00015605503,0.00014260519],"domain_scores_gemma":[0.99911064,0.000017257262,0.0004902564,0.00017169687,0.00013253768,0.000077630226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032754647,0.00013757416,0.00043130966,0.000030650095,0.00007967788,0.0000065007043,0.00023623828,0.00023703362,0.000083330095],"category_scores_gemma":[0.000056429093,0.00008391266,0.0004291448,0.00020831419,0.00011913603,0.0000032385167,0.000043932254,0.00012205075,3.1207257e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072319825,0.00007804706,0.0013133516,0.0000119207025,0.0003212415,0.0000013015283,0.000032014847,0.0000853548,0.9972965,0.000004617696,0.00018726662,0.000596076],"study_design_scores_gemma":[0.0003703623,0.0005115515,0.0025410203,0.000032024993,0.0002288973,0.000016958978,0.00007727837,0.000018176996,0.9953508,0.000026204343,0.00072637096,0.000100371304],"about_ca_topic_score_codex":0.0000034578895,"about_ca_topic_score_gemma":4.025261e-7,"teacher_disagreement_score":0.0019457053,"about_ca_system_score_codex":0.00000896841,"about_ca_system_score_gemma":0.00002206917,"threshold_uncertainty_score":0.34218588},"labels":[],"label_agreement":null},{"id":"W1979861016","doi":"10.1016/s0898-6568(03)00056-1","title":"Activation of ERK1/2 by platelet-activating factor receptor is independent of receptor internalisation and G-protein activation","year":2003,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Cell biology; G protein-coupled receptor; G protein-coupled receptor kinase; Phosphorylation; Arrestin; MAPK/ERK pathway; Receptor; Signal transduction; Biology; Chemistry; Biochemistry","score_opus":0.013901815840494047,"score_gpt":0.2192346846310253,"score_spread":0.20533286879053125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979861016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84814316,0.0002344326,0.15115622,0.000017596565,0.00007468894,0.00024862282,0.000018082394,0.000007690645,0.000099523226],"genre_scores_gemma":[0.9954931,0.00005941276,0.0039470145,0.000028587496,0.000070077556,0.000014256237,0.0001470939,0.000035070098,0.0002053514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985962,0.000121178084,0.00046336197,0.00036570715,0.00026697983,0.0001866106],"domain_scores_gemma":[0.9990624,0.000032209577,0.00049904926,0.00017228641,0.00016910699,0.00006490457],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034042093,0.00019770775,0.00023422888,0.00007933364,0.00007468928,0.000024787269,0.00011351685,0.00023820641,0.0004331116],"category_scores_gemma":[0.0001626035,0.00020443714,0.00008447079,0.00011362887,0.00003998072,0.000028402836,0.000035570312,0.00014247728,0.0000016586376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008286875,0.00004726157,0.00013864678,0.000069291724,0.0000648117,8.012072e-8,0.00035308383,0.00007678111,0.9956679,0.00018070554,0.00006562443,0.0032529423],"study_design_scores_gemma":[0.00046214854,0.00020907326,0.0000096134445,0.00015934091,0.000004101252,4.7544714e-7,0.00034906002,0.00020465159,0.9945215,0.00012593258,0.0037553222,0.00019876877],"about_ca_topic_score_codex":0.00004070063,"about_ca_topic_score_gemma":4.0587688e-7,"teacher_disagreement_score":0.14735,"about_ca_system_score_codex":0.000032332257,"about_ca_system_score_gemma":0.00004722822,"threshold_uncertainty_score":0.83367044},"labels":[],"label_agreement":null},{"id":"W1979897535","doi":"10.1016/j.lfs.2003.09.028","title":"Homo- and hetero-oligomerization of G protein-coupled receptors","year":2003,"lang":"en","type":"review","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto; Canada Research Chairs","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"G protein-coupled receptor; Receptor; Rhodopsin-like receptors; Rhodopsin; Biology; Class C GPCR; D2-like receptor; D1-like receptor; Function (biology); Dopamine receptor; Cell biology; Functional selectivity; Neuroscience; Computational biology; Biochemistry; Dopamine receptor D3; Metabotropic receptor; Agonist","score_opus":0.033012998389327024,"score_gpt":0.30094623154444283,"score_spread":0.2679332331551158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979897535","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0023701924,0.996142,0.0005451172,0.0000037655088,0.00027721835,0.00038685958,0.000007393126,0.000004801882,0.0002626438],"genre_scores_gemma":[0.00041588923,0.9975495,0.0015255081,0.000022144897,0.00010290841,0.000036922414,0.000034617897,0.000014732549,0.0002977957],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99882793,0.0000982601,0.00033000697,0.00039972155,0.00017036984,0.0001737055],"domain_scores_gemma":[0.9994359,0.0000095848545,0.0002902751,0.00015240931,0.00003634024,0.00007551231],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038209234,0.0001898455,0.00048103096,0.00008136137,0.00010262422,0.000028547434,0.00021114529,0.00019707762,0.000089604415],"category_scores_gemma":[0.00009592525,0.00014104474,0.00012927111,0.00024137448,0.00019856443,0.0000045040074,0.000059871432,0.000060201746,0.000003743218],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010734909,0.000090027585,0.00003114825,0.00816517,0.00019905044,0.0000011695967,0.00008467226,0.000017530498,0.14709443,0.0013716541,0.00023905134,0.84269536],"study_design_scores_gemma":[0.00007433154,0.00030326692,2.6035804e-7,0.0010595877,0.00005572622,0.0000067221376,0.000032611904,0.000013180424,0.009287044,0.000051939554,0.98885983,0.00025550407],"about_ca_topic_score_codex":0.0000062487516,"about_ca_topic_score_gemma":0.0000010464558,"teacher_disagreement_score":0.98862076,"about_ca_system_score_codex":0.000004117129,"about_ca_system_score_gemma":0.00020894702,"threshold_uncertainty_score":0.5751638},"labels":[],"label_agreement":null},{"id":"W1980133880","doi":"10.1016/j.bpj.2009.12.2257","title":"Conformational Changes in GPCR Surface and Core Probed by [13C]-Methyl NMR Spectroscopy","year":2010,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Chemistry; Transmembrane domain; Extracellular; Nuclear magnetic resonance spectroscopy; Salt bridge; Ligand (biochemistry); Allosteric regulation; Stereochemistry; Transmembrane protein; Conformational change; Biophysics; Receptor; Biochemistry; Biology","score_opus":0.0087997847106634,"score_gpt":0.2517027763381537,"score_spread":0.2429029916274903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980133880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99844056,0.0000665725,0.0007290486,0.0003567272,0.00018402071,0.00008272453,0.000016343623,0.0000043791324,0.00011964709],"genre_scores_gemma":[0.99621147,0.00011744814,0.0028786466,0.00016172102,0.00048102555,0.0000027324093,0.000035998983,0.0000115769,0.00009935209],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993243,0.000022103472,0.00015103967,0.00015202547,0.0001426319,0.00020785758],"domain_scores_gemma":[0.99965096,0.000010075305,0.00008324505,0.00008422474,0.00005120813,0.00012031652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017829782,0.0001173967,0.00012865372,0.00002337932,0.00008042551,0.000063120075,0.00010945193,0.0001193799,0.00010754854],"category_scores_gemma":[0.000024560968,0.00009734567,0.00004246574,0.00004957635,0.00006091636,0.000007943898,0.000043094155,0.00030135573,0.0000058333617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004256958,0.00004410026,0.00038976796,0.000004897312,0.00001122491,0.0000021338922,0.000038635495,0.0000056552267,0.9977661,0.0003404867,0.000833601,0.000520871],"study_design_scores_gemma":[0.00048164,0.0002352733,0.00060490286,0.000008614797,0.000004668198,0.000048437436,0.000044489338,0.0003127157,0.99191874,0.00027072916,0.005934218,0.00013558047],"about_ca_topic_score_codex":0.000006090702,"about_ca_topic_score_gemma":0.00001778404,"teacher_disagreement_score":0.005847326,"about_ca_system_score_codex":0.000007141504,"about_ca_system_score_gemma":0.00004070698,"threshold_uncertainty_score":0.39696413},"labels":[],"label_agreement":null},{"id":"W1980470416","doi":"10.1016/s0736-5748(00)00033-2","title":"Coupling of dopamine receptor subtypes to multiple and diverse G proteins","year":2000,"lang":"en","type":"review","venue":"International Journal of Developmental Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; U.S. Public Health Service; National Parkinson Foundation","keywords":"Dopamine receptor; Receptor; D1-like receptor; Biology; D2-like receptor; Dopamine; Dopaminergic; G protein-coupled receptor; Signal transduction; G protein; Adenylyl cyclase; Dopamine receptor D2; G protein-coupled receptor kinase; Cell biology; Neuroscience; Dopamine receptor D3; Biochemistry","score_opus":0.03160407027539564,"score_gpt":0.3005726401685868,"score_spread":0.2689685698931912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980470416","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21780424,0.77465284,0.0034018504,0.00005388963,0.0031498238,0.0007152921,0.0001369397,0.000007308591,0.00007779967],"genre_scores_gemma":[0.013175062,0.9810552,0.0052550794,0.00005992333,0.00019281612,0.0000057970897,0.000015218118,0.000018998317,0.00022188305],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99874705,0.000017179922,0.0005105469,0.00022962315,0.00037789444,0.00011768531],"domain_scores_gemma":[0.9992679,0.000020052803,0.00039992522,0.000059613216,0.00015361434,0.00009890412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002121379,0.00016069779,0.0003434131,0.00017250823,0.000040486044,0.000039479844,0.0005190735,0.0000727041,0.000039688533],"category_scores_gemma":[0.0001889487,0.00013061117,0.00012150499,0.00010439657,0.000060349816,0.0000126918185,0.00019661609,0.00011104,0.0000032553444],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097437114,0.00009430697,0.00015485974,0.00024098199,0.00007065029,0.000026922151,0.000058056678,0.00011497689,0.37484905,0.0000075596777,0.00015696313,0.6241282],"study_design_scores_gemma":[0.0002158741,0.00026187566,0.000020859992,0.0016063619,0.000022363316,0.00029497643,0.000028003155,0.000015544594,0.052351113,0.0000019041407,0.94499373,0.00018738682],"about_ca_topic_score_codex":0.000003836797,"about_ca_topic_score_gemma":0.0000017016401,"teacher_disagreement_score":0.9448368,"about_ca_system_score_codex":0.000034694374,"about_ca_system_score_gemma":0.00025711817,"threshold_uncertainty_score":0.5326169},"labels":[],"label_agreement":null},{"id":"W1980587229","doi":"10.1124/jpet.112.199190","title":"Interruption of the Ionic Lock in the Bradykinin B2 Receptor Results in Constitutive Internalization and Turns Several Antagonists into Strong Agonists","year":2012,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Internalization; G protein-coupled receptor; Receptor; Rhodopsin; Mutant; G protein; Chemistry; HEK 293 cells; Stereochemistry; Bradykinin; Arrestin; Biophysics; Biochemistry; Biology; Gene","score_opus":0.025824880080460605,"score_gpt":0.3426622114286121,"score_spread":0.3168373313481515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980587229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994727,0.0038633184,0.00028778898,0.0003648329,0.00059575826,0.00011468759,0.000003881302,6.7795065e-7,0.00004205193],"genre_scores_gemma":[0.9984386,0.0006845969,0.00015156192,0.0005406436,0.00016087886,0.0000029843427,0.000004454159,0.000005355863,0.000010900329],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991199,0.00025447173,0.00032903484,0.00008493247,0.00008545379,0.00012622896],"domain_scores_gemma":[0.9996287,0.000024121293,0.00023598035,0.00004948222,0.000035915087,0.000025775003],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004687483,0.00009450051,0.00012932067,0.000044373057,0.0000405408,0.000012240879,0.00012547782,0.00008839788,0.000012638644],"category_scores_gemma":[0.00000817134,0.000060406262,0.00003938753,0.00006527574,0.00016747233,0.000020878619,0.000060152128,0.00017800601,1.4476521e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007259443,0.0001593395,0.0036030416,0.000007409696,0.000057932877,0.000001360155,0.0056716516,0.00009096643,0.98901546,0.00018022697,0.00006962985,0.00041705737],"study_design_scores_gemma":[0.0019349036,0.00044194813,0.0014117326,0.000038138543,0.00002557041,0.00010232368,0.0025043976,0.00018416569,0.9906293,0.000063201835,0.0025850274,0.00007925079],"about_ca_topic_score_codex":0.000010215593,"about_ca_topic_score_gemma":0.000008955208,"teacher_disagreement_score":0.0037116215,"about_ca_system_score_codex":0.000038397182,"about_ca_system_score_gemma":0.000044766846,"threshold_uncertainty_score":0.24632959},"labels":[],"label_agreement":null},{"id":"W1980826200","doi":"10.1089/adt.2009.0232","title":"Comparing Label-Free Biosensors for Pharmacological Screening With Cell-Based Functional Assays","year":2010,"lang":"en","type":"article","venue":"Assay and Drug Development Technologies","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"G protein-coupled receptor; Biosensor; Receptor; Drug discovery; Agonist; Biophysics; Inverse agonist; Chemistry; Biology; Cell biology; Biochemistry","score_opus":0.01937051294922435,"score_gpt":0.2311518415962623,"score_spread":0.21178132864703794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980826200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8905,0.00017557043,0.10796659,0.00044930432,0.00014158012,0.00025637686,0.000005767703,0.00020217383,0.00030263935],"genre_scores_gemma":[0.8412759,0.000017210936,0.15823817,0.00008355502,0.00003620681,0.000100329606,0.000062022926,0.000014855304,0.00017175813],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900186,0.000018266415,0.00017225336,0.00038797085,0.00013529105,0.00028432958],"domain_scores_gemma":[0.99954927,0.00006158603,0.00008045999,0.00018278493,0.00008303002,0.000042867137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041423747,0.00019648601,0.00016314632,0.000076150616,0.00029699784,0.00004518021,0.00022743306,0.0002138377,0.000016563585],"category_scores_gemma":[0.000107494554,0.00014996108,0.000032867752,0.00008247544,0.00012934972,0.0000065498853,0.00017450805,0.0002086064,0.0000015205414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015269032,0.000067605324,0.005294934,0.000020512023,0.000056600555,0.0000024112455,0.000016348304,0.00011693472,0.9820795,0.00038811736,0.0015608516,0.010243509],"study_design_scores_gemma":[0.001423655,0.000106621235,0.00056081486,0.000012740988,0.000019082529,0.0000056771282,0.0002945368,0.00073202257,0.9794348,0.00019568932,0.016938537,0.0002758368],"about_ca_topic_score_codex":0.0000019026616,"about_ca_topic_score_gemma":0.000024286004,"teacher_disagreement_score":0.05027158,"about_ca_system_score_codex":0.000006823138,"about_ca_system_score_gemma":0.000070564325,"threshold_uncertainty_score":0.61152357},"labels":[],"label_agreement":null},{"id":"W1981420707","doi":"10.1021/jm050155n","title":"Radiosynthesis and Evaluation of [<sup>11</sup>C]-(+)-4-Propyl-3,4,4a,5,6,10b-hexahydro-2<i>H</i>-naphtho[1,2-<i>b</i>][1,4]oxazin-9-ol as a Potential Radiotracer for in Vivo Imaging of the Dopamine D2 High-Affinity State with Positron Emission Tomography","year":2005,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":226,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Chemistry; Dopamine receptor D2; Radiosynthesis; Agonist; Radioligand; Biodistribution; Dopamine; Receptor; Dopamine receptor; In vivo; Ligand (biochemistry); Positron emission tomography; Biochemistry; Neuroscience; In vitro; Psychology","score_opus":0.004942876852272141,"score_gpt":0.23369658041006008,"score_spread":0.22875370355778796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981420707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99526566,0.002862943,0.0009934107,0.00045505667,0.00006545591,0.00027402668,0.000022739063,0.0000025804254,0.00005810317],"genre_scores_gemma":[0.99728835,0.00025845194,0.0018858396,0.00005475,0.0004214986,0.000008589862,0.000008497889,0.000027254691,0.000046788988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977908,0.00013555787,0.0007368662,0.00027441722,0.0008016572,0.00026068024],"domain_scores_gemma":[0.9982443,0.000060585848,0.00080381345,0.0002475015,0.0005008212,0.00014300304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017781913,0.00024058484,0.0004499945,0.00008967712,0.00007144479,0.000015638736,0.00027112683,0.00013702946,0.00008569988],"category_scores_gemma":[0.00023473642,0.00016329027,0.0002073794,0.00016109215,0.00015887959,0.000024461222,0.000052770847,0.00024020304,4.885666e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010343676,0.0001433818,0.0029493622,0.00016653069,0.000115210394,0.0000060929906,0.00016094375,0.0038884575,0.9853784,0.0000012788696,0.00016970951,0.005986252],"study_design_scores_gemma":[0.0034037957,0.0003624872,0.0006590364,0.0005019868,0.0003373334,0.00040656538,0.0003891962,0.0031848887,0.99016786,0.00008183322,0.00033164336,0.00017336506],"about_ca_topic_score_codex":0.00003134273,"about_ca_topic_score_gemma":0.0000052886926,"teacher_disagreement_score":0.0058128866,"about_ca_system_score_codex":0.00005735675,"about_ca_system_score_gemma":0.0002967473,"threshold_uncertainty_score":0.6658784},"labels":[],"label_agreement":null},{"id":"W1981568254","doi":"10.1016/j.tips.2007.06.005","title":"The evasive nature of drug efficacy: implications for drug discovery","year":2007,"lang":"en","type":"review","venue":"Trends in Pharmacological Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":351,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Heart and Stroke Foundation of Canada","keywords":"Functional selectivity; Context (archaeology); Drug; Pharmacology; Drug discovery; Intrinsic activity; Receptor; Computational biology; Signalling; Signal transduction; Inverse agonist; G protein-coupled receptor; Neuroscience; Biology; Agonist; Bioinformatics; Cell biology; Genetics","score_opus":0.07803994855292964,"score_gpt":0.4503130536582783,"score_spread":0.3722731051053486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981568254","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001426429,0.99645025,0.00010462857,0.00018316456,0.00046577465,0.00044642217,0.00009297385,0.0000065438894,0.0008238136],"genre_scores_gemma":[0.008646872,0.9893985,0.0003708893,0.00008209854,0.00028376945,0.00017344685,0.00009369657,0.000010732696,0.000940007],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99835724,0.00014396156,0.00045870608,0.00051551743,0.00015538165,0.0003692132],"domain_scores_gemma":[0.99887365,0.0005567774,0.00030066568,0.00016245386,0.000046959514,0.00005947997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013185564,0.00022956908,0.00047620767,0.000103034545,0.0002743889,0.000052989813,0.0009452305,0.0002729291,0.000036455833],"category_scores_gemma":[0.00011589158,0.000118104836,0.00042163226,0.0005719739,0.00041225622,0.000006161302,0.00016588243,0.00029790617,8.428585e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022484153,0.00010028142,0.0000075916955,0.00014556172,0.000058326375,5.275967e-7,0.00001321299,0.000019068328,0.0029449936,0.0022887783,0.004076739,0.9903224],"study_design_scores_gemma":[0.00021771732,0.00012935142,0.00002736662,0.00019285046,0.00013981813,0.0000034760037,0.000029097204,0.0000051638667,0.004845009,0.0004503959,0.9937462,0.00021350339],"about_ca_topic_score_codex":0.0000030800327,"about_ca_topic_score_gemma":0.000019805902,"teacher_disagreement_score":0.9901089,"about_ca_system_score_codex":0.000025392505,"about_ca_system_score_gemma":0.00013184715,"threshold_uncertainty_score":0.48161754},"labels":[],"label_agreement":null},{"id":"W1981638964","doi":"10.1006/gcen.2000.7591","title":"Characterization of [3H]CGP 12177 Binding to β-Adrenergic Receptors in Intact Eel Hepatocytes","year":2001,"lang":"en","type":"article","venue":"General and Comparative Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Ministero dell'Università e della Ricerca","keywords":"Phentolamine; Adenylyl cyclase; Biology; Receptor; Endocrinology; Internal medicine; Adrenergic receptor; Prazosin; Atenolol; Alprenolol; Adrenergic; Stimulation; Intracellular; Propranolol; Biochemistry; Antagonist","score_opus":0.030863099632612367,"score_gpt":0.27276831252264955,"score_spread":0.2419052128900372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981638964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99765116,0.00022897424,0.0012806194,0.000072388684,0.0002209896,0.00016071014,0.000009170514,0.00000766743,0.0003683295],"genre_scores_gemma":[0.9978348,0.00046553332,0.0006054376,0.00012229779,0.00014156074,0.000036700127,0.00013089176,0.000008269579,0.00065450737],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998996,0.00009092318,0.00025546426,0.0003160991,0.000063066065,0.00027840422],"domain_scores_gemma":[0.9996753,0.000008419074,0.000082054044,0.000119474535,0.00004856318,0.00006619503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000558376,0.00015523151,0.00026889812,0.00012255792,0.000050635033,0.0000106223915,0.00010710804,0.00007546835,0.000120095705],"category_scores_gemma":[0.000008953355,0.00014309211,0.00004212096,0.00014114362,0.000044672946,0.000007005531,0.000099376506,0.000072505725,0.000008470268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012481111,0.00003736323,0.014605594,0.0000042114134,0.000022647495,0.0000039883057,0.0001738226,0.00013427188,0.9814293,0.0012857025,0.00004457482,0.0021337627],"study_design_scores_gemma":[0.00044783656,0.00045344047,0.009452577,0.000012565511,0.000005514323,0.000027705972,0.00014569581,0.00021012255,0.97573936,0.00005879681,0.013267946,0.00017841416],"about_ca_topic_score_codex":0.00006815855,"about_ca_topic_score_gemma":0.00007513639,"teacher_disagreement_score":0.0132233715,"about_ca_system_score_codex":0.000012982234,"about_ca_system_score_gemma":0.000021146361,"threshold_uncertainty_score":0.5835127},"labels":[],"label_agreement":null},{"id":"W1981664395","doi":"10.1016/s0014-2999(00)00815-3","title":"Polymorphisms in dopamine receptors: what do they tell us?","year":2000,"lang":"en","type":"review","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":179,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Dopamine receptor; Dopamine; Pharmacogenetics; Receptor; Dopamine receptor D2; Dopamine receptor D3; Schizophrenia (object-oriented programming); Biology; Genetic association; Drug response; Neuroscience; Disease; Genetic linkage; Genetics; Drug; Gene; Pharmacology; Medicine; Genotype; Internal medicine; Single-nucleotide polymorphism; Psychiatry","score_opus":0.023494867262517233,"score_gpt":0.30321765704537373,"score_spread":0.2797227897828565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981664395","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0026514214,0.9928493,0.000040374918,0.000038524722,0.0030691558,0.00025252812,0.0000088325705,0.000005521015,0.0010843388],"genre_scores_gemma":[0.0006887011,0.9949467,0.00029504125,0.0002881236,0.003068272,0.00000435016,0.000046339977,0.00013098483,0.0005314525],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99555093,0.0020502836,0.001348808,0.00041948518,0.00019506678,0.0004354353],"domain_scores_gemma":[0.9984437,0.000050246577,0.0010123953,0.00022518318,0.00008986303,0.00017860896],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015780776,0.00048649753,0.0012444558,0.00035305714,0.000049887134,0.000086551634,0.0008491989,0.00021380506,0.0023888848],"category_scores_gemma":[0.000030410323,0.0003852398,0.0006646708,0.00015751662,0.000068550835,0.000020658505,0.00015446995,0.00079344853,0.00014273355],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011263499,0.00013416946,0.000002655614,0.0003159227,0.00029538252,0.0006706293,0.000047698548,0.000038479324,0.019542897,0.0000030849064,0.0052953702,0.9735411],"study_design_scores_gemma":[0.00082650216,0.00073215633,9.4338446e-7,0.002441271,0.00033005315,0.00083981367,0.00002069204,5.5444735e-7,0.004008026,0.00000510688,0.9904326,0.0003622347],"about_ca_topic_score_codex":0.000001525539,"about_ca_topic_score_gemma":9.4234696e-7,"teacher_disagreement_score":0.9851373,"about_ca_system_score_codex":0.000057326168,"about_ca_system_score_gemma":0.00022956952,"threshold_uncertainty_score":0.9998599},"labels":[],"label_agreement":null},{"id":"W1982187763","doi":"10.1139/o04-113","title":"Regulation of G protein-coupled receptor endocytosis by ARF6 GTP-binding proteins","year":2004,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Internalization; Endocytosis; Cell biology; Endocytic cycle; G protein; G protein-coupled receptor; Receptor; GTPase-activating protein; Intracellular; Biology; GTP-binding protein regulators; Endosome; Signal transduction; Biochemistry","score_opus":0.012816669298156579,"score_gpt":0.25053678942398,"score_spread":0.23772012012582341,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982187763","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01423778,0.9835875,0.00037989882,0.0000070496094,0.00012530893,0.00095279975,0.00031837763,0.000019158415,0.00037213092],"genre_scores_gemma":[0.012684141,0.97888476,0.0012421529,0.000008291318,0.00030990847,0.00028250043,0.004262394,0.000069978545,0.0022558991],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977697,0.00011083868,0.00071114,0.0008940277,0.000110265995,0.00040400907],"domain_scores_gemma":[0.99858886,0.000019552292,0.0007058331,0.00046861343,0.0000788024,0.00013832554],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0002534758,0.0005571551,0.001036589,0.00006118283,0.00011099045,0.000022509863,0.00031851296,0.0013573654,0.00020289289],"category_scores_gemma":[0.00006075996,0.0004886338,0.00037054002,0.00013709544,0.00017985747,0.0000036682907,0.00017527738,0.00025967462,0.000009388006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027215428,0.00006642609,9.350701e-7,0.006926713,0.0000993689,4.6480875e-7,0.0000059431864,3.0953228e-7,0.9436738,0.000032458403,0.000103788465,0.049062606],"study_design_scores_gemma":[0.00026034872,0.00020727153,2.4928198e-8,0.0013011241,0.000094159936,0.000008606958,0.0000109944185,8.752706e-7,0.63010603,0.00002389342,0.36765236,0.00033434],"about_ca_topic_score_codex":0.000017160168,"about_ca_topic_score_gemma":3.8073094e-7,"teacher_disagreement_score":0.36754856,"about_ca_system_score_codex":0.00005417809,"about_ca_system_score_gemma":0.00030816448,"threshold_uncertainty_score":0.9999391},"labels":[],"label_agreement":null},{"id":"W1982511319","doi":"10.1016/j.lfs.2004.11.001","title":"β adrenergic receptor-mediated atrial specific up-regulation of RGS5","year":2004,"lang":"en","type":"article","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Internal medicine; Western blot; Endocrinology; Agonist; Biology; Skeletal muscle; Receptor; Medicine; Biochemistry; Gene","score_opus":0.018721024346710198,"score_gpt":0.2468811807474263,"score_spread":0.2281601564007161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982511319","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99497706,0.001100189,0.0022377823,0.000101337435,0.00093243254,0.000078661345,0.00000793207,0.000009674835,0.00055493746],"genre_scores_gemma":[0.99659574,0.0002107798,0.0024094097,0.000050382587,0.0005499849,0.0000017982792,0.000044897173,0.0000056951485,0.0001313057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911785,0.000030392846,0.00020235592,0.0002581464,0.00022950517,0.00016175299],"domain_scores_gemma":[0.9996382,0.000009971686,0.00010741304,0.0001243488,0.00005171246,0.00006835197],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032505646,0.00008431076,0.000104787105,0.000049220773,0.00010528776,0.000017253838,0.00019840557,0.000085609485,0.0002617237],"category_scores_gemma":[0.00008025858,0.00007017241,0.000089498586,0.00022220377,0.00016446497,0.00000697688,0.000039069353,0.000032357846,0.00001836008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028764513,0.00001076833,0.00019806164,0.000002541446,0.0000075983803,7.9384954e-8,0.000050841976,0.0042162547,0.99283075,0.0016895129,0.00033435065,0.0006304706],"study_design_scores_gemma":[0.00057392224,0.0003232269,0.0003901984,0.000013567135,0.000003824984,0.000001633459,0.000166824,0.0000690376,0.9885405,0.0008938059,0.008894367,0.00012914321],"about_ca_topic_score_codex":0.000025537009,"about_ca_topic_score_gemma":0.000005461724,"teacher_disagreement_score":0.008560017,"about_ca_system_score_codex":0.000006988196,"about_ca_system_score_gemma":0.00013202553,"threshold_uncertainty_score":0.28656912},"labels":[],"label_agreement":null},{"id":"W1982565473","doi":"10.1038/ijosup.2014.2","title":"Peripheral actions of GPCRs in energy homeostasis: view from the Chair","year":2014,"lang":"en","type":"article","venue":"International Journal of Obesity Supplements","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"G protein-coupled receptor; Energy homeostasis; Receptor; Neuroscience; Biology; Drug discovery; Homeostasis; Computational biology; Drug; Energy expenditure; Bioinformatics; Pharmacology; Cell biology; Endocrinology; Biochemistry","score_opus":0.012458639235659623,"score_gpt":0.26792706658786647,"score_spread":0.2554684273522069,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982565473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9835037,0.00045117753,0.0146001745,0.00065361755,0.0006303104,0.00003128055,0.00006114562,8.993058e-7,0.000067710316],"genre_scores_gemma":[0.99781877,0.0005517126,0.0008400893,0.00029496988,0.00038785007,0.0000018365405,0.0000667076,0.000006170692,0.000031918407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915206,0.00007933161,0.00032520609,0.00008692092,0.00027029484,0.00008617375],"domain_scores_gemma":[0.99944377,0.000019036384,0.00023017217,0.0000940257,0.000181062,0.000031915642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025735542,0.00007066255,0.000115635645,0.000043928383,0.000025546122,0.000018762761,0.00036835263,0.000040705243,0.00036842297],"category_scores_gemma":[0.000047583784,0.000053073345,0.000102137776,0.000033481407,0.000016886363,0.000009728497,0.000069553775,0.00006854257,8.401044e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037495414,0.000614849,0.12244988,0.00000837258,0.000892197,0.000013108768,0.0005197968,0.0014141094,0.8108009,0.0019151715,0.007524676,0.053471994],"study_design_scores_gemma":[0.0027133473,0.0005078953,0.038134217,0.00015875779,0.000043352324,0.000035856654,0.00077879644,0.00042864092,0.64506835,0.0021367134,0.30977777,0.00021629555],"about_ca_topic_score_codex":0.00022831163,"about_ca_topic_score_gemma":0.00022954005,"teacher_disagreement_score":0.3022531,"about_ca_system_score_codex":0.000026083171,"about_ca_system_score_gemma":0.000039114584,"threshold_uncertainty_score":0.40339732},"labels":[],"label_agreement":null},{"id":"W1982573687","doi":"10.1016/s0014-2999(02)02224-0","title":"Pharmacological characterization of human NPFF1 and NPFF2 receptors expressed in CHO cells by using NPY Y1 receptor antagonists","year":2002,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":143,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; Douglas College; McGill University","funders":"Centre National de la Recherche Scientifique","keywords":"Receptor; Chinese hamster ovary cell; Neuropeptide Y receptor; G protein-coupled receptor; Biology; Chemistry; Antagonist; Neuropeptide; Endocrinology; Biochemistry; Internal medicine; Medicine","score_opus":0.021816166399377928,"score_gpt":0.2712468386545463,"score_spread":0.24943067225516838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982573687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99707186,0.00045117887,0.001130683,0.00013291526,0.00087975076,0.00016759844,0.00002314147,0.0000045531274,0.00013830443],"genre_scores_gemma":[0.9964993,0.0017931209,0.0006708375,0.00028553326,0.00053177716,0.0000017693676,0.0000249722,0.00003572075,0.00015696087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99792814,0.00075657724,0.0006778041,0.00024637213,0.0001330884,0.00025798817],"domain_scores_gemma":[0.9990864,0.00001769352,0.00058906747,0.000070179194,0.00011121294,0.00012548934],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0006947827,0.00018633375,0.00031567222,0.00012216048,0.000073231386,0.00001858699,0.00024201498,0.000084495616,0.0015058174],"category_scores_gemma":[0.000016468792,0.00017437224,0.00008937858,0.00010433466,0.00011134056,0.000019486837,0.00009026983,0.00024590988,0.000004449347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014487597,0.0002016247,0.000153405,0.00001656202,0.00006505168,0.000030645315,0.0001529566,0.000052308387,0.99137807,0.000001856256,0.0049954737,0.002807169],"study_design_scores_gemma":[0.0019713189,0.00071106973,0.000059478134,0.0000249269,0.000047694524,0.000030369643,0.000034458866,0.00014809631,0.96150106,0.000001775486,0.035306726,0.0001630053],"about_ca_topic_score_codex":0.0000013372633,"about_ca_topic_score_gemma":1.240141e-7,"teacher_disagreement_score":0.030311251,"about_ca_system_score_codex":0.000024939707,"about_ca_system_score_gemma":0.000017032058,"threshold_uncertainty_score":0.99940693},"labels":[],"label_agreement":null},{"id":"W1983501707","doi":"10.1074/jbc.m500078200","title":"The Glucagon-like Peptide-2 Receptor C Terminus Modulates β-Arrestin-2 Association but Is Dispensable for Ligand-induced Desensitization, Endocytosis, and G-protein-dependent Effector Activation","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"G protein-coupled receptor; Internalization; Homologous desensitization; Cell biology; Receptor; Biology; Arrestin; Enzyme-linked receptor; G protein-coupled receptor kinase; G protein; 5-HT5A receptor; Endocytosis; Signal transduction; Glucagon-like peptide 1 receptor; Agonist; Biochemistry","score_opus":0.014262926936432592,"score_gpt":0.24084648636246067,"score_spread":0.2265835594260281,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983501707","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99750555,0.00032031446,0.0011975073,0.0005807032,0.00012310759,0.00021006253,0.000018067689,0.0000074063005,0.00003726704],"genre_scores_gemma":[0.99658924,0.00029805407,0.0011809802,0.00014468789,0.0009806515,0.0000181144,0.00004175539,0.00001471922,0.0007318171],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988807,0.000055565964,0.00040300807,0.00023228611,0.00018200284,0.00024644367],"domain_scores_gemma":[0.99878,0.0001538345,0.0005249587,0.00012823586,0.0003119497,0.00010100052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057941454,0.00017150385,0.00021400179,0.00001304657,0.00022613641,0.0000893482,0.00015427227,0.0002961559,0.000025287365],"category_scores_gemma":[0.00081893284,0.0001114873,0.00013856393,0.000043744,0.000030550844,0.000014365014,0.00005401073,0.00016132926,0.0000020348991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020459504,0.000037571735,0.00052543666,0.00001639747,0.00007341737,7.176241e-7,0.00001678386,0.000022883005,0.99496335,0.00000323232,0.0009278236,0.0032078119],"study_design_scores_gemma":[0.0006527545,0.00027363314,0.00021323361,0.00004116171,0.000020621133,0.000027317685,0.00006599674,0.00016143988,0.99000466,0.000087721804,0.008301786,0.00014966413],"about_ca_topic_score_codex":0.0000031693696,"about_ca_topic_score_gemma":9.287279e-7,"teacher_disagreement_score":0.007373963,"about_ca_system_score_codex":0.00008769044,"about_ca_system_score_gemma":0.0000535195,"threshold_uncertainty_score":0.454632},"labels":[],"label_agreement":null},{"id":"W1983741285","doi":"10.1097/00005344-200036051-00018","title":"Development of a Photolabile Ligand for the Endothelin-A Receptor of Endothelin","year":2000,"lang":"en","type":"article","venue":"Journal of Cardiovascular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Armand Frappier Museum; Institut National de la Recherche Scientifique; Université du Québec à Montréal","funders":"","keywords":"Endothelin receptor; Receptor; Chemistry; Stereochemistry; Guinea pig; Ligand (biochemistry); Antagonist; Peptide; Endothelins; Endothelin 1; Pharmacology; Biochemistry; Internal medicine; Biology; Medicine","score_opus":0.01305886056781518,"score_gpt":0.25997832379150837,"score_spread":0.24691946322369318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983741285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.960425,0.019939762,0.018357577,0.00005215519,0.0006735328,0.00039168223,0.00003482761,0.0000022391853,0.00012318099],"genre_scores_gemma":[0.9766973,0.005375768,0.016475556,0.00012133915,0.00089303247,0.00003797807,0.0000060230327,0.000033517597,0.00035944526],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985856,0.00012787631,0.0006864591,0.00015072947,0.00025601377,0.00019334927],"domain_scores_gemma":[0.9990067,0.00007223255,0.00032472124,0.00019580412,0.00033837973,0.00006216732],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015110187,0.00013822873,0.0004847934,0.00005639956,0.00006633454,0.0000053996605,0.00032146848,0.0001164649,0.0005492937],"category_scores_gemma":[0.00004267293,0.0000967258,0.00094464293,0.00006180968,0.00007416266,0.00000520726,0.00003193666,0.00011648886,0.0000023325858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005246873,0.00007366889,0.0000067759315,0.00004200144,0.003078586,0.0000017749977,0.00019759907,0.002198888,0.9420181,0.0000057938532,0.0005033407,0.051348805],"study_design_scores_gemma":[0.0013894432,0.00020969685,0.0000033460112,0.000011395141,0.00028567793,0.00004169735,0.000071471644,0.000038732367,0.64493924,0.0000100527595,0.3529351,0.00006413154],"about_ca_topic_score_codex":0.000002574101,"about_ca_topic_score_gemma":5.7798286e-7,"teacher_disagreement_score":0.35243177,"about_ca_system_score_codex":0.000015520545,"about_ca_system_score_gemma":0.0002429054,"threshold_uncertainty_score":0.60143805},"labels":[],"label_agreement":null},{"id":"W1983878290","doi":"10.1016/j.neuropharm.2012.10.029","title":"Supra-normal stimulation of dopamine D1 receptors in the prelimbic cortex blocks behavioral expression of both aversive and rewarding associative memories through a cyclic-AMP-dependent signaling pathway","year":2012,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Infralimbic cortex; Stimulation; Dopamine; Neuroscience; Dopamine receptor; Psychology; Aversive Stimulus; Cortex (anatomy); Receptor; Prefrontal cortex; Chemistry; Cognition; Biochemistry","score_opus":0.020980916428964082,"score_gpt":0.2933499365616178,"score_spread":0.2723690201326537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983878290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998132,0.0004539422,0.0005384628,0.000019038083,0.00045820948,0.00030897063,0.000018040542,0.00000575102,0.000065610424],"genre_scores_gemma":[0.9990411,0.00016059818,0.00040294667,0.00008662895,0.00017123514,0.000020840753,0.000037867263,0.000018848827,0.000059966394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984843,0.00043264404,0.00035983414,0.00024482192,0.00019840404,0.00027998994],"domain_scores_gemma":[0.9992697,0.00014405053,0.0003298196,0.00012677089,0.00008452839,0.000045107263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042861426,0.00016245544,0.0002559926,0.000053607153,0.00008176282,0.000007737519,0.00014619196,0.00015877686,0.00010309072],"category_scores_gemma":[0.000084034466,0.00013456917,0.000072181094,0.00009997695,0.0000883168,0.000024523155,0.00013034798,0.00018827527,5.713459e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024910882,0.00017523639,0.012859469,0.000018559911,0.000021799058,0.000002605909,0.0025073565,0.00039936733,0.98335284,0.0000123507125,0.000060158272,0.0003411645],"study_design_scores_gemma":[0.0010143714,0.0005821764,0.0022318722,0.000018196388,0.00006162802,0.000009778883,0.00089038897,0.000035652687,0.994403,0.00001398522,0.00061419705,0.00012473633],"about_ca_topic_score_codex":0.000048847505,"about_ca_topic_score_gemma":0.0000064701967,"teacher_disagreement_score":0.011050193,"about_ca_system_score_codex":0.000019164396,"about_ca_system_score_gemma":0.000033404693,"threshold_uncertainty_score":0.5487572},"labels":[],"label_agreement":null},{"id":"W1983957619","doi":"10.3390/ijms15023003","title":"Recent Progress in Understanding Subtype Specific Regulation of NMDA Receptors by G Protein Coupled Receptors (GPCRs)","year":2014,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; University of Manitoba; Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"G protein-coupled receptor; Rhodopsin-like receptors; Receptor; Biology; Ionotropic effect; Class C GPCR; Neuroscience; NMDA receptor; Long-term depression; Glutamate receptor; Cell biology; Signal transduction; Metabotropic receptor; Metabotropic glutamate receptor; AMPA receptor; Genetics","score_opus":0.04132122269260058,"score_gpt":0.3171401288740678,"score_spread":0.2758189061814672,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983957619","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006633656,0.980814,0.010123737,0.00010432818,0.0018024368,0.00038778078,0.000008460089,0.0000037302482,0.00012186477],"genre_scores_gemma":[0.019153956,0.97833604,0.0020469658,0.000017173592,0.00026739482,0.000012347549,0.00007643685,0.00003313612,0.000056524732],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99691284,0.00030124042,0.0011668768,0.00038877386,0.0009962094,0.00023403496],"domain_scores_gemma":[0.9975626,0.000034746707,0.001755833,0.0001669199,0.00039372634,0.00008617961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017602362,0.00028235425,0.00071357586,0.00044484757,0.00005021868,0.000093395865,0.0009971968,0.00027199523,0.00014850117],"category_scores_gemma":[0.00013543399,0.00023020082,0.00035605681,0.0003817149,0.00024758157,0.000022099643,0.00010800099,0.0002455038,0.0000028261006],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016999879,0.00025594328,0.00011633997,0.00060049084,0.0004786119,0.000020573405,0.00009241288,0.00023476162,0.08964343,0.0027043042,0.0016018993,0.9040812],"study_design_scores_gemma":[0.00050948974,0.0006301097,0.0000023507807,0.005221122,0.00004932124,0.00005120421,0.00009770461,0.00005460814,0.03526405,0.00069843757,0.957034,0.0003876332],"about_ca_topic_score_codex":0.0000031200611,"about_ca_topic_score_gemma":0.000002909345,"teacher_disagreement_score":0.95543206,"about_ca_system_score_codex":0.00020678196,"about_ca_system_score_gemma":0.00040283235,"threshold_uncertainty_score":0.93873173},"labels":[],"label_agreement":null},{"id":"W1984064578","doi":"10.1038/npp.2013.152","title":"Neuroimaging in Psychiatric Pharmacogenetics Research: The Promise and Pitfalls","year":2013,"lang":"en","type":"review","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of General Medical Sciences; National Cancer Institute; University of California, Los Angeles; Memorial Sloan-Kettering Cancer Center; GlaxoSmithKline; Ohio State University; National Institutes of Health; Moffitt Cancer Center; Yale University; National Institute on Drug Abuse; AstraZeneca; Canadian Institutes of Health Research; Centre for Addiction and Mental Health Foundation; National Institute of Mental Health; Pfizer; Ontario Ministry of Research and Innovation; U.S. Department of Veterans Affairs","keywords":"Neuroimaging; Pharmacogenetics; Schizophrenia (object-oriented programming); Psychiatry; Addiction; Psychology; Imaging genetics; Drug response; Major depressive disorder; Drug development; Clinical psychology; Medicine; Neuroscience; Drug; Genotype; Cognition; Genetics; Biology","score_opus":0.10803477890535651,"score_gpt":0.4281949720707171,"score_spread":0.3201601931653606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984064578","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0075905053,0.98774314,0.000013422182,0.00019951953,0.0016769909,0.0021416014,0.000014463162,0.00001700045,0.0006033667],"genre_scores_gemma":[0.00042374383,0.99636656,0.00016069676,0.0006564357,0.001047599,0.0005808199,0.00002954177,0.00014173638,0.00059287687],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99524647,0.0019290643,0.0007019296,0.0010808238,0.0002631858,0.00077850354],"domain_scores_gemma":[0.9987298,0.00018868789,0.00024691405,0.00053726794,0.00010997497,0.0001873191],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009508546,0.00051392417,0.0007604223,0.00037662624,0.00021719628,0.000098624165,0.00083867245,0.00037002374,0.00021933205],"category_scores_gemma":[0.00007333438,0.00037133,0.00023446958,0.0006063004,0.00025563245,0.000005601286,0.00045484406,0.0014098289,0.00008700803],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000527116,0.00014919593,0.000018878964,0.0016977421,0.000106376065,0.000056618825,0.000039459388,0.0000074558106,0.0605729,0.000038050337,0.019751461,0.91750914],"study_design_scores_gemma":[0.00067772646,0.00023495845,0.000011828111,0.00015784174,0.00015834218,0.00016116044,0.000009332123,0.000035064768,0.00026620287,0.000054878376,0.9978892,0.00034342788],"about_ca_topic_score_codex":0.000009793757,"about_ca_topic_score_gemma":0.0000035395367,"teacher_disagreement_score":0.9781378,"about_ca_system_score_codex":0.00002266978,"about_ca_system_score_gemma":0.00021663343,"threshold_uncertainty_score":0.9998739},"labels":[],"label_agreement":null},{"id":"W1984427209","doi":"10.1210/en.2013-1713","title":"Regulation of Hepatic Glucose Production by Gq-Coupled Receptors: Potential New Targets for Treatment of Type 2 Diabetes","year":2013,"lang":"en","type":"letter","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Receptor; Biology; G protein; Gq alpha subunit; Cell biology; Adenylyl cyclase; Phospholipase C; Signal transduction; Intracellular; Rhodopsin-like receptors; Diacylglycerol kinase; HEK 293 cells; Biochemistry; Protein kinase C; Agonist; Metabotropic receptor","score_opus":0.010112453366001257,"score_gpt":0.22751972506070273,"score_spread":0.21740727169470148,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984427209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.955836,0.011160248,0.0033401293,0.02298594,0.0046218196,0.0019036431,0.00008895699,0.000030311468,0.00003295721],"genre_scores_gemma":[0.8526831,0.010582302,0.01754535,0.011187193,0.023345355,0.0009011012,0.03224496,0.00049039617,0.051020212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985734,0.000076152515,0.00041388973,0.00046610626,0.00011347796,0.00035692772],"domain_scores_gemma":[0.9989845,0.000019623283,0.0003959409,0.00036096005,0.00020555356,0.00003342063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000039879847,0.0002672922,0.00048851967,0.00008610486,0.000036264802,0.00000644844,0.00013654916,0.00049184327,0.00028916477],"category_scores_gemma":[0.00007188411,0.00024180063,0.0001885751,0.00005319957,0.00006465729,0.000004605597,0.00003143047,0.000083880564,0.000006229863],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053759202,0.00004870005,0.000024256587,0.00007769404,0.00018793039,4.550425e-7,0.000017821605,0.00003747814,0.72285855,0.000005014037,0.27322882,0.0034595456],"study_design_scores_gemma":[0.0004605563,0.0015437469,0.000009858628,0.000015878626,0.00009421307,0.0000032522762,0.000005396492,0.00010987185,0.7362655,0.00021723668,0.2611227,0.00015183186],"about_ca_topic_score_codex":0.00010597563,"about_ca_topic_score_gemma":0.0000032004887,"teacher_disagreement_score":0.10315286,"about_ca_system_score_codex":0.0000331556,"about_ca_system_score_gemma":0.000087481145,"threshold_uncertainty_score":0.98603433},"labels":[],"label_agreement":null},{"id":"W1984429646","doi":"10.1016/j.tips.2005.01.004","title":"Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation","year":2005,"lang":"en","type":"review","venue":"Trends in Pharmacological Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":436,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Association pour la Recherche sur le Cancer; Styrelsen för Internationellt Utvecklingssamarbete; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"G protein-coupled receptor; Receptor; Function (biology); Biology; Rhodopsin-like receptors; Cell biology; Signal transduction; Computational biology; Biochemistry; Chemistry","score_opus":0.036408777638758785,"score_gpt":0.35638189623709265,"score_spread":0.3199731185983339,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984429646","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12461168,0.8749626,0.000017296197,0.000027652635,0.000060913128,0.00018714869,0.000008594061,0.0000049328182,0.00011913617],"genre_scores_gemma":[0.091845945,0.9068716,0.0010840703,0.000011823824,0.000076962795,0.000042701336,0.000030920764,0.0000066586044,0.000029295834],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987564,0.0001593621,0.00036284435,0.00042135164,0.00011346429,0.0001865981],"domain_scores_gemma":[0.99968266,0.00002806711,0.00018347325,0.000051751846,0.000011232299,0.000042795964],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048232303,0.00017739784,0.00042725276,0.00021032817,0.000055168166,0.000026136135,0.00014968109,0.00020450875,0.00022734837],"category_scores_gemma":[0.00003469048,0.00012605866,0.00006010115,0.00040416553,0.00015455825,0.000010473944,0.00008919064,0.00010568841,5.532518e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000097763295,0.00002607634,0.000014350285,0.00008057636,0.0000074379604,3.6208758e-7,0.000016603184,0.000012546983,0.22899392,0.000020794665,0.0000033237106,0.77081424],"study_design_scores_gemma":[0.0018964518,0.0020726782,0.00040101382,0.0045435196,0.00045382505,0.000035907353,0.00044329648,0.006529107,0.28985003,0.0003476662,0.6910637,0.0023628215],"about_ca_topic_score_codex":0.000014472999,"about_ca_topic_score_gemma":0.0000138909545,"teacher_disagreement_score":0.7684514,"about_ca_system_score_codex":0.000013704783,"about_ca_system_score_gemma":0.000023915045,"threshold_uncertainty_score":0.5140523},"labels":[],"label_agreement":null},{"id":"W1984809490","doi":"10.1016/j.bpj.2008.12.781","title":"Oligomeric Size of the M2 Muscarinic Receptor in the Plasma Membrane of Live Cells as Determined by Quantitative FRET","year":2009,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Förster resonance energy transfer; Oligomer; Fluorescence; Tetramer; Acceptor; Chinese hamster ovary cell; Chemistry; Green fluorescent protein; Yellow fluorescent protein; Biophysics; Receptor; Biology; Biochemistry; Organic chemistry; Physics","score_opus":0.008202416809425486,"score_gpt":0.24442785723463548,"score_spread":0.23622544042521,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984809490","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991969,0.00007978256,0.00007869556,0.00019497225,0.0001663871,0.00011326124,0.000017368615,0.0000013175168,0.0001513441],"genre_scores_gemma":[0.99888957,0.00016391576,0.0005317974,0.0001850417,0.00014146486,0.0000021223634,0.0000034656468,0.000008115693,0.00007452961],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989328,0.0001949386,0.0003142569,0.00014786296,0.0002370798,0.00017309027],"domain_scores_gemma":[0.99933696,0.000090395275,0.00026250377,0.00018869275,0.00007427826,0.000047169815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022727263,0.0001269935,0.0002125787,0.000019910616,0.00005582994,0.000016782227,0.0004007129,0.00009139382,0.00006893973],"category_scores_gemma":[0.00009319444,0.000072421906,0.0002158707,0.00015417319,0.000092405884,0.0000054075913,0.000036164292,0.00019551677,0.0000052294336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014331342,0.00015033469,0.000015585541,0.0000054315324,0.00002577768,0.0000014551572,0.0003327691,0.000028063145,0.99807316,0.00013996624,0.0003251265,0.0007590068],"study_design_scores_gemma":[0.00047485338,0.0010658471,0.00033992738,0.000032397413,0.000018210016,0.0000125333645,0.00043796597,0.00008586657,0.9968869,0.00019552505,0.0003587052,0.00009124281],"about_ca_topic_score_codex":0.000017649065,"about_ca_topic_score_gemma":0.0000020483626,"teacher_disagreement_score":0.0011862444,"about_ca_system_score_codex":0.000008709583,"about_ca_system_score_gemma":0.00005381738,"threshold_uncertainty_score":0.29532796},"labels":[],"label_agreement":null},{"id":"W1984901324","doi":"10.1016/j.cellsig.2009.07.003","title":"A cell surface inactive mutant of the human lutropin receptor (hLHR) attenuates signaling of wild-type or constitutively active receptors via heterodimerization","year":2009,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Cell biology; Mutant; Receptor; HEK 293 cells; Chemistry; Wild type; Signal transduction; Cell; Biology; Biochemistry; Gene","score_opus":0.013038719048472314,"score_gpt":0.23048142404287408,"score_spread":0.21744270499440177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984901324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9541116,0.0005137729,0.044382054,0.000021396134,0.00030681698,0.0004280846,0.000024081892,0.000015013924,0.00019717436],"genre_scores_gemma":[0.9963017,0.000077092955,0.003157692,0.00004563824,0.00012524716,0.0000035634084,0.00009928215,0.00003472476,0.00015504591],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980853,0.00023552658,0.0005737953,0.00048017083,0.00030328182,0.00032188548],"domain_scores_gemma":[0.9985482,0.000045084675,0.0006322271,0.00031725067,0.00037530327,0.000081949314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029190813,0.0003081173,0.0004087884,0.00006247798,0.00022541937,0.00001968288,0.00036543698,0.0002458567,0.00016612033],"category_scores_gemma":[0.00007473901,0.00023775602,0.00021973277,0.0003503189,0.00018623521,0.0000143160105,0.00007900465,0.00021175253,0.0000035773082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028931533,0.00013714591,0.00012151649,0.000039345585,0.00008878897,0.0000015445347,0.00039973098,0.009419392,0.9889191,0.00014747404,0.000019515459,0.00041712998],"study_design_scores_gemma":[0.00052002753,0.0006835997,0.000019633735,0.00016576101,0.000067532426,0.0000025509587,0.0004584588,0.00068910397,0.99669415,0.00014469239,0.00026396394,0.00029053297],"about_ca_topic_score_codex":0.00003040007,"about_ca_topic_score_gemma":0.0000016012608,"teacher_disagreement_score":0.04219011,"about_ca_system_score_codex":0.00004555101,"about_ca_system_score_gemma":0.00015512954,"threshold_uncertainty_score":0.9695409},"labels":[],"label_agreement":null},{"id":"W1985350249","doi":"10.1074/jbc.m109.051839","title":"The Fifth Transmembrane Domain of Angiotensin II Type 1 Receptor Participates in the Formation of the Ligand-binding Pocket and Undergoes a Counterclockwise Rotation upon Receptor Activation","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Transmembrane domain; Receptor; Cysteine; Mutant; Ligand (biochemistry); Receptor–ligand kinetics; Transmembrane protein; Chemistry; Binding site; Angiotensin II; Biophysics; Stereochemistry; Biochemistry; Biology; Enzyme; Gene","score_opus":0.01863396474848375,"score_gpt":0.24884245421659307,"score_spread":0.23020848946810932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985350249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99800426,0.00047216794,0.00019728941,0.0011544699,0.000046798694,0.00009842494,0.0000048120187,0.0000012159679,0.000020570635],"genre_scores_gemma":[0.99898136,0.0005915915,0.00023382157,0.00007996635,0.00008527277,0.0000015434438,0.000014163686,0.0000030957117,0.000009164026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999162,0.000104531944,0.00039385023,0.000085327985,0.0001417097,0.0001125458],"domain_scores_gemma":[0.99927807,0.00007706443,0.00039883083,0.00010118662,0.00012207028,0.000022798575],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000686393,0.00008967184,0.0001460754,0.0000123220225,0.00010454233,0.00001579114,0.00016827688,0.0001419597,0.000013043937],"category_scores_gemma":[0.00018632668,0.000041281884,0.00008790728,0.000109877976,0.00006061117,0.000011812463,0.000018327304,0.00013448745,9.525767e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034505958,0.000047652058,0.00011043766,0.00001253457,0.000012694397,1.3803326e-7,0.0004415453,0.00004683383,0.99781656,0.000018521125,0.00009513259,0.0010528628],"study_design_scores_gemma":[0.00034970106,0.00045383928,0.00061110593,0.00008723052,0.000010143239,0.000011390903,0.0010458537,0.00004127053,0.9960967,0.00047837608,0.00076021283,0.0000541855],"about_ca_topic_score_codex":0.0000016289009,"about_ca_topic_score_gemma":0.0000013473815,"teacher_disagreement_score":0.0017198976,"about_ca_system_score_codex":0.000014765693,"about_ca_system_score_gemma":0.000030317344,"threshold_uncertainty_score":0.16834264},"labels":[],"label_agreement":null},{"id":"W1985428937","doi":"10.1159/000138018","title":"Evidence for an Indirect Component of the Action of Histamine on Canine Portal Vein","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Histamine; Tachyphylaxis; Phentolamine; Tyramine; Endocrinology; Internal medicine; Prazosin; Yohimbine; Methysergide; Metiamide; Chemistry; Histamine H2 receptor; Receptor; Pharmacology; Biology; Medicine; Serotonin; Antagonist","score_opus":0.13765596980576453,"score_gpt":0.3650910649018004,"score_spread":0.22743509509603585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985428937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984217,0.00026557827,0.0004747158,0.000074489464,0.00047235747,0.00020460658,0.000015673566,0.0000029069856,0.00006793315],"genre_scores_gemma":[0.99915445,0.00016817039,0.00017513456,0.00014507119,0.00015579857,0.000021231876,0.000022948667,0.000007972138,0.00014925313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948066,0.00006185917,0.00015420133,0.00013801694,0.0000677951,0.000097448734],"domain_scores_gemma":[0.99964166,0.000026289214,0.0001352873,0.000103921164,0.000065416025,0.000027449127],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012575915,0.000065322245,0.000116494026,0.00002144982,0.000046830235,6.811278e-7,0.00012082637,0.000055611563,0.00010831341],"category_scores_gemma":[0.000027225224,0.0000502028,0.0000644584,0.000036509915,0.00005933685,0.0000025028426,0.000027033948,0.000043247084,3.0836608e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029721102,0.00009957569,0.00038500183,0.000017005332,0.000032041316,5.9135385e-7,0.000044930162,0.0002590124,0.9965774,0.000023551564,0.0016581826,0.0006055438],"study_design_scores_gemma":[0.000434008,0.00086227746,0.0013885237,0.000009335528,0.000024652234,0.000010627121,0.0000148802355,0.00021936517,0.99453753,0.000008366827,0.002440297,0.000050127695],"about_ca_topic_score_codex":0.000036134315,"about_ca_topic_score_gemma":0.00001824916,"teacher_disagreement_score":0.002039814,"about_ca_system_score_codex":0.000010016536,"about_ca_system_score_gemma":0.000056924622,"threshold_uncertainty_score":0.20472108},"labels":[],"label_agreement":null},{"id":"W1985712419","doi":"10.1160/th14-08-0679","title":"Diversity and impact of rare variants in genes encoding the platelet G protein-coupled receptors","year":2015,"lang":"en","type":"article","venue":"Thrombosis and Haemostasis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"University of Bristol; National Institute for Health and Care Research; British Heart Foundation; Wellcome Trust","keywords":"G protein-coupled receptor; Biology; Gene; Genetics; Exome sequencing; Population; Exome; splice; Computational biology; Receptor; Bioinformatics; Mutation; Medicine","score_opus":0.061338268836629316,"score_gpt":0.29344734076514933,"score_spread":0.23210907192852,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985712419","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985063,0.0009863302,0.00011233341,0.00006472859,0.000045613284,0.00020632877,0.000013466992,0.0000037894586,0.00006109356],"genre_scores_gemma":[0.99876916,0.0008374255,0.00029057203,0.000022420194,0.0000364588,0.0000058570213,0.000011029926,0.00000894635,0.000018100354],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993297,0.000058250516,0.0001445665,0.00020578728,0.00010420388,0.00015747875],"domain_scores_gemma":[0.9996414,0.00001120715,0.00007474962,0.00014271228,0.000052407075,0.00007749583],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036344855,0.00011985788,0.0001932638,0.00003467264,0.00025524452,0.00001575324,0.000102268496,0.00009462485,0.00003824928],"category_scores_gemma":[0.00003727528,0.00008183705,0.00005249246,0.000084152234,0.000070897295,0.000008661891,0.00047558476,0.000056984263,3.486284e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002517516,0.00008015945,0.10097881,0.00003924247,0.00023115774,0.0000027864605,0.0042316695,0.00009123283,0.8808108,0.00014831875,0.0003168214,0.01281724],"study_design_scores_gemma":[0.003210193,0.0012359425,0.0841802,0.00012460205,0.00006796977,0.000018026189,0.0033056855,0.00082229485,0.9049935,0.0007870092,0.00070282596,0.00055179413],"about_ca_topic_score_codex":0.00073220354,"about_ca_topic_score_gemma":0.00005405692,"teacher_disagreement_score":0.024182642,"about_ca_system_score_codex":0.0000144641435,"about_ca_system_score_gemma":0.00003491297,"threshold_uncertainty_score":0.33372182},"labels":[],"label_agreement":null},{"id":"W1985825056","doi":"10.1189/jlb.1106681","title":"1α,25-Dihydroxycholecalciferol activates binding of CREB to a CRE site in the<i>CD14</i>promoter and drives promoter activity in a phosphatidylinositol-3 kinase-dependent manner","year":2007,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Infectious Diseases Centre","funders":"Canadian Institutes of Health Research","keywords":"Phosphatidylinositol; Biology; CREB; Kinase; Cell biology; Binding site; Molecular biology; Cancer research; Transcription factor; Gene; Genetics","score_opus":0.011614967238819794,"score_gpt":0.27953454501594344,"score_spread":0.26791957777712366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985825056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966952,0.0005347239,0.001915006,0.00035948068,0.00016495008,0.00025452606,0.0000062235504,0.0000023048306,0.00006754965],"genre_scores_gemma":[0.9983997,0.00014142455,0.0009916902,0.000206912,0.00019645122,0.0000051543047,0.0000045652214,0.000017744369,0.000036371664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984142,0.00021727443,0.0005567259,0.00029154177,0.0001552147,0.0003650313],"domain_scores_gemma":[0.9991903,0.00007532104,0.00036072297,0.00018868582,0.00008591426,0.00009910007],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014051137,0.00020701207,0.00039437404,0.0002723264,0.000043679476,0.000024240619,0.00026626824,0.00027058483,0.000017411301],"category_scores_gemma":[0.00009725119,0.00014495231,0.000116185125,0.00016975413,0.000069028756,0.000019205048,0.00010800022,0.00032066973,0.0000015084586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00074159424,0.00016859123,0.014227966,0.00002036151,0.00003722855,0.000052720112,0.00074236724,0.000027866836,0.9796101,0.00004663032,0.000021449661,0.0043031094],"study_design_scores_gemma":[0.0012771803,0.0013736343,0.0151410615,0.00009397848,0.000015079016,0.00011449895,0.00025187997,0.000023810233,0.9799123,0.00009838275,0.0015303333,0.00016788559],"about_ca_topic_score_codex":0.000052157346,"about_ca_topic_score_gemma":0.000112404676,"teacher_disagreement_score":0.0041352236,"about_ca_system_score_codex":0.0000427064,"about_ca_system_score_gemma":0.000054115237,"threshold_uncertainty_score":0.59109837},"labels":[],"label_agreement":null},{"id":"W1986138054","doi":"10.1016/j.bcp.2007.04.009","title":"Cholesterol as a determinant of cooperativity in the M2 muscarinic cholinergic receptor","year":2007,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Muscarinic acetylcholine receptor; Cooperativity; Chemistry; Receptor; Membrane; Cholesterol; Cooperative binding; Sf9; Sarcolemma; Biophysics; Binding site; Biochemistry; Biology","score_opus":0.011315060013061888,"score_gpt":0.31020976735243233,"score_spread":0.29889470733937046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986138054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979639,0.0005135934,0.00044221152,0.00012920743,0.00031973008,0.00025965337,0.0000068929044,0.000006228014,0.00035855718],"genre_scores_gemma":[0.99791217,0.00012134483,0.0002243011,0.001202277,0.00037197347,0.000028175118,0.000038132916,0.000015067253,0.00008655362],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872595,0.00012509947,0.0003578137,0.0003272973,0.00012930579,0.0003345362],"domain_scores_gemma":[0.9994991,0.000056856923,0.0001025754,0.00020385726,0.000061202285,0.000076424054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007291955,0.00016240963,0.00020326582,0.000051475003,0.000037884765,0.000007567341,0.0003500517,0.00023703347,0.00023361082],"category_scores_gemma":[0.000054771106,0.00012075069,0.000100545185,0.00015157434,0.00013316183,0.000003419986,0.00010522078,0.00020386996,0.000013335031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018437798,0.00018229117,0.00025253987,0.000011186336,0.000018851862,0.000004995686,0.00010316244,0.0000072273274,0.9936486,0.000031892363,0.0047411853,0.00081370544],"study_design_scores_gemma":[0.0009209316,0.00030540721,0.00071461406,0.000007876954,0.000016686598,0.000026899004,0.000084129664,0.000029745072,0.9885314,0.000014725259,0.009209408,0.00013816266],"about_ca_topic_score_codex":0.00002961194,"about_ca_topic_score_gemma":0.000005664753,"teacher_disagreement_score":0.005117171,"about_ca_system_score_codex":0.000016259395,"about_ca_system_score_gemma":0.000053913802,"threshold_uncertainty_score":0.49240702},"labels":[],"label_agreement":null},{"id":"W1986185847","doi":"10.1523/jneurosci.5074-06.2007","title":"Regulation of Akt Signaling by D<sub>2</sub>and D<sub>3</sub>Dopamine Receptors<i>In Vivo</i>","year":2007,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":267,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression","keywords":"Protein kinase B; Dopamine receptor D2; Dopaminergic; Dopamine; Dopamine receptor; Receptor; Biology; Dopamine receptor D3; SCH-23390; Signal transduction; Dopamine receptor D1; Pharmacology; Chemistry; Cell biology; Endocrinology; Internal medicine; Biochemistry; Medicine","score_opus":0.009044440069997182,"score_gpt":0.22855571031390787,"score_spread":0.21951127024391068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986185847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99235594,0.00041791314,0.0066417404,0.000052559608,0.00041641237,0.00007997318,0.0000028254115,0.0000020753344,0.00003054761],"genre_scores_gemma":[0.99893653,0.00044580223,0.00033639357,0.00013721231,0.00011502672,7.127452e-7,0.0000011582887,0.000013719674,0.0000134525735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984437,0.000067559,0.00062244333,0.00026360684,0.00032906217,0.0002736223],"domain_scores_gemma":[0.99918264,0.00004175225,0.00043324564,0.00012359027,0.00010790754,0.000110843204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012456648,0.00013615373,0.00022299186,0.00017685685,0.000048509457,0.000025057418,0.00019763957,0.00010610082,0.0000030589424],"category_scores_gemma":[0.0002210318,0.0001269812,0.00007516307,0.00031711697,0.000099597615,0.000029193483,0.000053345088,0.00017219878,2.6205436e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009806164,0.000060985745,0.0009200618,0.000011423162,0.0000017169472,0.000011452158,0.00003601879,0.00049275835,0.99506223,0.000013200449,0.00009806495,0.0031940383],"study_design_scores_gemma":[0.0004533212,0.00047472175,0.0020004432,0.000070914415,0.0000053470703,0.000074992,0.000041678366,0.00020220385,0.99584055,0.00007213545,0.0006421816,0.000121525714],"about_ca_topic_score_codex":0.0000029772807,"about_ca_topic_score_gemma":0.000009697168,"teacher_disagreement_score":0.0065805693,"about_ca_system_score_codex":0.000023094097,"about_ca_system_score_gemma":0.00005588712,"threshold_uncertainty_score":0.5178143},"labels":[],"label_agreement":null},{"id":"W1986406984","doi":"10.1016/s0531-5131(03)00606-x","title":"Platelet-activating factor receptor: differential regulation and signaling by agonists and inverse agonists","year":2003,"lang":"en","type":"article","venue":"International Congress Series","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Inverse agonist; Receptor; G protein-coupled receptor; Platelet-activating factor receptor; Cell biology; Agonist; Mutant; Signal transduction; Enzyme-linked receptor; Platelet-activating factor; Biology; Chemistry; Pharmacology; Biochemistry; Endocrinology; Antagonist; Gene","score_opus":0.009605832475017926,"score_gpt":0.2331718960924271,"score_spread":0.2235660636174092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986406984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99799645,0.00027380633,0.0006294887,0.000078059216,0.00060188957,0.00008396405,0.00003427665,0.000008737944,0.00029333308],"genre_scores_gemma":[0.9979226,0.00019013985,0.00079654396,0.000037606507,0.00007739637,0.00001047861,0.00013574638,0.000015138407,0.00081436324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992584,0.000048070713,0.00017891268,0.00026321143,0.000121323654,0.00013008798],"domain_scores_gemma":[0.9997177,0.000016694228,0.00008842308,0.00006879319,0.000059907605,0.00004844743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007138336,0.00012962398,0.00011124219,0.000040637355,0.000082262064,0.00010373487,0.000063423795,0.00010082557,0.00022691158],"category_scores_gemma":[0.00008956397,0.00013164543,0.00002364754,0.000025618228,0.00006354411,0.000027510569,0.000044593326,0.00007141246,0.0000010144424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000083527,0.000013591092,0.0020266757,0.000009659773,0.00003305441,0.0000014381122,0.00011735336,0.00001657402,0.99489397,0.0011278372,0.0002218709,0.0014544607],"study_design_scores_gemma":[0.00053120917,0.00006877145,0.000498386,0.000032009626,0.0000014718026,0.000015910571,0.00017135788,0.00013302125,0.9572757,0.00031315038,0.040785227,0.00017382212],"about_ca_topic_score_codex":0.000016066895,"about_ca_topic_score_gemma":0.000021214773,"teacher_disagreement_score":0.040563356,"about_ca_system_score_codex":0.000017023056,"about_ca_system_score_gemma":0.000017488006,"threshold_uncertainty_score":0.5368345},"labels":[],"label_agreement":null},{"id":"W1986655120","doi":"10.1016/j.euroneuro.2004.12.006","title":"Possible association between the gamma-aminobutyric acid type B receptor 1 (GABBR1) gene and schizophrenia","year":2005,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Schizophrenia (object-oriented programming); Association (psychology); Genetics; Psychology; Biology; Psychiatry; Psychotherapist","score_opus":0.012102434740004312,"score_gpt":0.25649810473990187,"score_spread":0.24439566999989756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986655120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945235,0.0012285137,0.00018212889,0.0010797648,0.0009979812,0.00022116872,0.000017699118,0.000067615285,0.0016815771],"genre_scores_gemma":[0.9907605,0.0011092116,0.00096579513,0.001955931,0.003134708,0.0000075181197,0.00005700492,0.000097623044,0.0019117185],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979778,0.00066140096,0.00031613783,0.0004964175,0.00016057702,0.00038766107],"domain_scores_gemma":[0.99923176,0.000045375447,0.0001992239,0.00028013933,0.00010543661,0.00013807595],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000621882,0.00023046507,0.00017952581,0.00005498054,0.00019928507,0.00006302035,0.00034696047,0.00010644627,0.00024631046],"category_scores_gemma":[0.00009842766,0.00018830148,0.0000777495,0.00017023059,0.000060315106,0.000010519191,0.00017712617,0.0002933639,0.00026050865],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015730735,0.000027674012,0.0017573982,0.0000036522215,0.00009364821,0.000004632865,0.000043557116,0.00003409808,0.9695785,0.000011103968,0.014685738,0.013602667],"study_design_scores_gemma":[0.0024662386,0.0007545788,0.036399443,0.000006386803,0.00014261235,0.00003858259,0.000017353983,0.00008959381,0.46933937,0.000015261088,0.49027392,0.00045666596],"about_ca_topic_score_codex":0.0000014120699,"about_ca_topic_score_gemma":9.897235e-7,"teacher_disagreement_score":0.50023913,"about_ca_system_score_codex":0.000025904916,"about_ca_system_score_gemma":0.00003234049,"threshold_uncertainty_score":0.76787114},"labels":[],"label_agreement":null},{"id":"W1987107538","doi":"10.1016/j.euroneuro.2006.07.004","title":"Neurokinin 1 receptor antagonism requires norepinephrine to increase serotonin function","year":2006,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Université de Montréal; McGill University","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute for Health and Care Research","keywords":"Autoreceptor; Serotonin; Locus coeruleus; Receptor; 5-HT receptor; Internal medicine; Endocrinology; Substance P; NK1 receptor antagonist; Chemistry; Dorsal raphe nucleus; 5-HT1A receptor; Antagonism; Tachykinin receptor 1; Biology; Serotonergic; Neuropeptide; Central nervous system; Medicine","score_opus":0.00875921335248425,"score_gpt":0.25142803914242745,"score_spread":0.2426688257899432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987107538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98605007,0.00014162465,0.0021111835,0.0004971599,0.0026064585,0.00049916306,0.000031069092,0.00019605803,0.007867191],"genre_scores_gemma":[0.9860846,0.000086584274,0.00081679935,0.007130441,0.0029877168,0.00004708774,0.00020739704,0.00020656313,0.0024328313],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99722075,0.00069577445,0.00048373808,0.0008881329,0.00018352685,0.000528089],"domain_scores_gemma":[0.9990067,0.000021665508,0.00015683536,0.00045746376,0.00011104414,0.00024629882],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003845257,0.00035054047,0.0002308958,0.00014802792,0.0001518713,0.000055301298,0.00040414772,0.0000860494,0.00048313243],"category_scores_gemma":[0.000058376623,0.0003602335,0.00013853448,0.00025587942,0.000065063134,0.0000104980045,0.0002501328,0.00023328546,0.0004822374],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00087796315,0.00012684663,0.00022517354,0.000008196746,0.000025575304,0.00007399437,0.000010852177,0.00046895666,0.9389645,0.00017866652,0.056335982,0.0027033212],"study_design_scores_gemma":[0.001636402,0.0013931749,0.012334967,0.000007008087,0.000034015437,0.00006494324,0.000008173769,0.00003943772,0.26129606,0.000032399847,0.722728,0.00042536287],"about_ca_topic_score_codex":0.000041835512,"about_ca_topic_score_gemma":0.0000052784862,"teacher_disagreement_score":0.6776684,"about_ca_system_score_codex":0.000020187477,"about_ca_system_score_gemma":0.00003334909,"threshold_uncertainty_score":0.99988496},"labels":[],"label_agreement":null},{"id":"W1987347300","doi":"10.1074/jbc.m114.631119","title":"Angiotensin II Type I and Prostaglandin F2α Receptors Cooperatively Modulate Signaling in Vascular Smooth Muscle Cells","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Jewish General Hospital; Montreal Heart Institute; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Angiotensin II; Receptor; Vascular smooth muscle; Agonist; Chemistry; Vasoconstriction; Endocrinology; Internal medicine; Signal transduction; Prostaglandin; G protein-coupled receptor; Allosteric regulation; Cell biology; Biology; Biochemistry; Medicine; Smooth muscle","score_opus":0.013193782444179443,"score_gpt":0.2221600393593152,"score_spread":0.20896625691513576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987347300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979338,0.0011016779,0.00063945935,0.000052146606,0.00012921121,0.0000649535,0.000002893243,0.000004657217,0.00007122066],"genre_scores_gemma":[0.99673754,0.0005311762,0.0022018484,0.000104499086,0.0003284571,0.0000011929608,0.000018061462,0.000013074203,0.00006416696],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989281,0.000087097804,0.0003811808,0.00025614304,0.00012244833,0.00022501696],"domain_scores_gemma":[0.99934185,0.00002409447,0.00019913922,0.000118560914,0.00019187876,0.00012450175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006413513,0.00017409153,0.00029882294,0.000026713662,0.00007540812,0.000026404474,0.00014395482,0.0002933059,0.000093668605],"category_scores_gemma":[0.00019673088,0.00012496654,0.00010082316,0.000115268296,0.00007369922,0.0000063868056,0.000094621435,0.00022716132,0.0000010137717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009119953,0.000054254346,0.00044068747,0.000011176611,0.000023913411,0.0000059588137,0.000045240085,0.00035015188,0.99740547,0.0000044156204,0.00026026217,0.0013072547],"study_design_scores_gemma":[0.00068601675,0.00066694996,0.0007772561,0.000053108943,0.000010901709,0.000010502649,0.000075439246,0.00016814744,0.98156774,0.00010210917,0.015682524,0.00019932752],"about_ca_topic_score_codex":0.0000030552978,"about_ca_topic_score_gemma":4.455776e-7,"teacher_disagreement_score":0.01583777,"about_ca_system_score_codex":0.000017400296,"about_ca_system_score_gemma":0.000038359285,"threshold_uncertainty_score":0.50959873},"labels":[],"label_agreement":null},{"id":"W1987605547","doi":"10.1016/j.bpj.2009.12.717","title":"Oligomeric Size and Configuration of the M2 Muscarinic and β2 Adrenergic Receptors in Live Cells as Determined by Pixel-Level FRET","year":2010,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Förster resonance energy transfer; Tetramer; Chemistry; Crystallography; Biophysics; Fluorescence; Physics; Optics; Biology","score_opus":0.0062568866661819374,"score_gpt":0.21868289967800467,"score_spread":0.21242601301182273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987605547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99926764,0.00006879555,0.00013676082,0.000058159923,0.00033648874,0.00007097481,0.000008464748,0.0000015607552,0.000051178235],"genre_scores_gemma":[0.9990126,0.0002025592,0.00032099744,0.00007674279,0.00021762941,0.0000026725318,0.00000392266,0.0000102129525,0.00015268703],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932784,0.000058770613,0.0002015263,0.00016508835,0.00010993823,0.00013686367],"domain_scores_gemma":[0.9995938,0.000029367546,0.00013573167,0.00010921229,0.00004580673,0.000086077474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011604266,0.00011175265,0.00014375866,0.00001749329,0.00006597207,0.000032890926,0.00011378328,0.00012278659,0.00006819975],"category_scores_gemma":[0.000050377213,0.00007862052,0.00006342216,0.00005613391,0.00012695053,0.000006746247,0.000056362016,0.00020638363,0.0000014953812],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033967044,0.000034810797,0.00021203882,0.000004580922,0.000012530308,7.3006083e-7,0.00006848126,0.0000017070145,0.99743176,0.00005889515,0.000056742858,0.0020837313],"study_design_scores_gemma":[0.000434097,0.00024013796,0.0019178046,0.000014069918,0.000012623618,0.00002892672,0.00007418445,0.00006571795,0.9963095,0.0001663761,0.00063227856,0.000104260434],"about_ca_topic_score_codex":0.000031770727,"about_ca_topic_score_gemma":0.000015580174,"teacher_disagreement_score":0.001979471,"about_ca_system_score_codex":0.0000044031713,"about_ca_system_score_gemma":0.000039216426,"threshold_uncertainty_score":0.3206052},"labels":[],"label_agreement":null},{"id":"W1987881358","doi":"10.1016/j.pbiomolbio.2009.01.010","title":"Mathematical simulations of ligand-gated and cell-type specific effects on the action potential of human atrium","year":2008,"lang":"en","type":"review","venue":"Progress in Biophysics and Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Division of Chemical, Bioengineering, Environmental, and Transport Systems; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Heritage Medical Research Institute; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada; National Institutes of Health; National Science Foundation","keywords":"Atrium (architecture); Type (biology); Action (physics); Ligand (biochemistry); Biological system; Biophysics; Chemistry; Physics; Biology; Receptor; Medicine; Cardiology; Biochemistry","score_opus":0.02337676290873872,"score_gpt":0.320232090097212,"score_spread":0.2968553271884733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987881358","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2442661,0.75461006,0.00044712066,0.0000075856674,0.00009208797,0.00053085777,0.000021800703,0.0000034725736,0.000020930112],"genre_scores_gemma":[0.4091917,0.5903664,0.00019249631,0.000006322671,0.00006305181,0.000012754905,0.00014235743,0.000021258795,0.0000036617255],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883735,0.00018685586,0.00037741533,0.00035070613,0.00007860204,0.00016909237],"domain_scores_gemma":[0.9992941,0.000051195293,0.00029416324,0.00026093674,0.00006386808,0.000035724206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009361005,0.00025623667,0.00064163364,0.00008365595,0.000060554252,0.000009494153,0.00013482526,0.00037397625,0.0000032464936],"category_scores_gemma":[0.000014637886,0.00017731535,0.00016016791,0.00014143286,0.00024513467,0.0000016641326,0.00011638078,0.000159435,5.6233426e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031754593,0.00016443865,0.000014484749,0.0023946634,0.00013751,0.000007316032,0.00002295064,0.000004410338,0.86239725,0.0043382826,0.000010461784,0.13047646],"study_design_scores_gemma":[0.0006364641,0.0018339106,0.00000912575,0.0015952641,0.00023370875,0.000029407935,0.000015544401,0.00006576868,0.9713381,0.00280271,0.020954093,0.00048592294],"about_ca_topic_score_codex":0.0000016972772,"about_ca_topic_score_gemma":1.9738178e-7,"teacher_disagreement_score":0.1649256,"about_ca_system_score_codex":0.0000056945314,"about_ca_system_score_gemma":0.000034716,"threshold_uncertainty_score":0.723071},"labels":[],"label_agreement":null},{"id":"W1987919585","doi":"10.1139/y99-134","title":"Considerations on pharmacodynamics and pharmacokinetics: Can everything be explained by the extent of drug binding to its receptor?","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pharmacodynamics; Drug; Pharmacokinetics; Pharmacology; Molecular Pharmacology; Biology; Receptor; Medicine; Internal medicine","score_opus":0.011348627699900818,"score_gpt":0.2561481364690696,"score_spread":0.24479950876916878,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987919585","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99472946,0.0012445754,0.00001721921,0.0031184931,0.0005214179,0.00016190246,0.00013364476,0.000001686583,0.00007162682],"genre_scores_gemma":[0.99381137,0.0010035374,0.000112427144,0.0045295223,0.00026627292,0.0000073428473,0.000021641943,0.000014400451,0.00023346463],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989567,0.00021719733,0.00030396966,0.00019508955,0.000060214817,0.00026683346],"domain_scores_gemma":[0.99923706,0.000094422285,0.00014175588,0.00007087575,0.00010969134,0.00034617848],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029983078,0.00015168902,0.00022370745,0.000097608216,0.0002535761,0.000013226914,0.00013491209,0.00009001464,0.0023930052],"category_scores_gemma":[0.000027681259,0.00012289852,0.000055160064,0.00006371465,0.00014510659,0.000007904853,0.000019189076,0.00023420477,0.000001740816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012209723,0.000016602304,0.000032366934,0.000014832263,0.00012004176,0.0000062070408,0.0005530166,0.0008320664,0.9789552,0.00007032141,0.018227113,0.0010501422],"study_design_scores_gemma":[0.0008570387,0.00040769845,0.00004607756,0.000016154252,0.000069164045,0.000084194275,0.00017354723,0.00018766774,0.97473353,0.00009993531,0.023186171,0.00013880178],"about_ca_topic_score_codex":0.00012666942,"about_ca_topic_score_gemma":0.00019730175,"teacher_disagreement_score":0.0049590585,"about_ca_system_score_codex":0.000021550619,"about_ca_system_score_gemma":0.00021663327,"threshold_uncertainty_score":0.99851894},"labels":[],"label_agreement":null},{"id":"W1988051697","doi":"10.1016/j.bpj.2009.12.202","title":"Efficacy As An Intrinsic Property of the M2 Muscarinic Receptor in Its Oligomeric State","year":2010,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; G protein-coupled receptor; Receptor; Muscarinic acetylcholine receptor; G protein; Ligand (biochemistry); Biophysics; Stereochemistry; Biochemistry; Biology","score_opus":0.009905686641952634,"score_gpt":0.24959623520453153,"score_spread":0.2396905485625789,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988051697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99894077,0.00002039639,0.00003173387,0.00010758779,0.00059914397,0.0001308797,0.000003862309,0.0000038075525,0.00016181372],"genre_scores_gemma":[0.9987863,0.000065415465,0.00021626342,0.00008907121,0.0005970343,0.0000038234443,0.0000041444237,0.000018259863,0.0002197224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990153,0.00010259634,0.00026759336,0.0002021234,0.00018834537,0.00022408496],"domain_scores_gemma":[0.99937797,0.000009258382,0.00014592813,0.00024716745,0.000095180745,0.00012452641],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021001117,0.00012866562,0.00016360018,0.000035033732,0.000075757656,0.000033724573,0.0003606616,0.00009932214,0.00012191393],"category_scores_gemma":[0.00009561779,0.000070210095,0.0001426092,0.00015142524,0.00007199908,0.000009342534,0.00010279187,0.00041799736,0.000018478831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010512804,0.00019590688,0.00018792291,0.0000045453803,0.000016666114,0.0000018903595,0.00006293548,0.000018295941,0.9868503,0.00008802255,0.000046654026,0.012421741],"study_design_scores_gemma":[0.00059442664,0.00041686717,0.00492005,0.0000182407,0.0000072716884,0.000030243302,0.000025166177,0.000051791034,0.9900826,0.00009931701,0.0036267405,0.0001272621],"about_ca_topic_score_codex":0.000020214871,"about_ca_topic_score_gemma":0.000011038014,"teacher_disagreement_score":0.012294479,"about_ca_system_score_codex":0.000009169579,"about_ca_system_score_gemma":0.000116802774,"threshold_uncertainty_score":0.28630847},"labels":[],"label_agreement":null},{"id":"W1988261552","doi":"10.1016/s0022-5193(03)00265-0","title":"Equilibrium competition binding assay: inhibition mechanism from a single dose response","year":2003,"lang":"en","type":"article","venue":"Journal of Theoretical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Mechanism (biology); Competition (biology); Chemistry; Biophysics; Biology; Physics; Ecology","score_opus":0.011340706623628271,"score_gpt":0.24837579998875017,"score_spread":0.2370350933651219,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988261552","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9075583,0.00020968563,0.09082951,0.0002982637,0.0005506188,0.000066248605,0.00002283042,0.0000060443417,0.00045848518],"genre_scores_gemma":[0.9938022,0.000036017525,0.005503388,0.00026125184,0.00030652154,0.0000019363779,0.000043055177,0.000018995224,0.000026674063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979682,0.0010127337,0.0004348285,0.0002143249,0.00012088029,0.00024900943],"domain_scores_gemma":[0.9991207,0.00017874593,0.0002637097,0.00016207497,0.00014485742,0.00012992685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016459172,0.00015012655,0.0002561456,0.000093621915,0.000046746714,0.000028981318,0.00012675929,0.00030357292,0.00076054304],"category_scores_gemma":[0.0010458593,0.00012106889,0.0001860568,0.000072870134,0.0001840263,0.000007472711,0.000053415504,0.0001929765,0.000016195778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00081196666,0.00007243237,0.000020851337,0.0000018437631,0.000038692142,0.000011998114,0.000017621314,0.000005210376,0.77986026,0.21891282,0.000050290866,0.00019602742],"study_design_scores_gemma":[0.00070921384,0.0015439709,0.0000075743246,0.00003084081,0.000026541875,0.000119580414,0.00008205056,0.000038844664,0.8384895,0.15695855,0.0018646598,0.00012869568],"about_ca_topic_score_codex":9.579501e-7,"about_ca_topic_score_gemma":3.651626e-7,"teacher_disagreement_score":0.08624384,"about_ca_system_score_codex":0.000035519683,"about_ca_system_score_gemma":0.00006944898,"threshold_uncertainty_score":0.83274126},"labels":[],"label_agreement":null},{"id":"W1988395319","doi":"10.1126/science.288.5463.154","title":"Receptors for Dopamine and Somatostatin: Formation of Hetero-Oligomers with Enhanced Functional Activity","year":2000,"lang":"en","type":"article","venue":"Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":880,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Heterotrimeric G protein; Somatostatin; Somatostatin receptor; D1-like receptor; D2-like receptor; Somatostatin receptor 3; Somatostatin receptor 1; Receptor; Dopamine; Dopamine receptor; G protein-coupled receptor; Crosstalk; Chemistry; Dopamine receptor D2; Neurotransmitter receptor; Cell biology; G protein; Neurotransmitter; Somatostatin receptor 2; Biology; Neuroscience; Biochemistry; Dopamine receptor D1","score_opus":0.008203360131617246,"score_gpt":0.2268458227555155,"score_spread":0.21864246262389828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988395319","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9636939,0.000024063516,0.03594274,0.000019048326,0.000048162023,0.000103242375,0.000005013988,0.0000030660174,0.00016076196],"genre_scores_gemma":[0.9965635,0.000025654164,0.003186248,0.000021715307,0.000022731421,0.00001175954,0.00000871756,0.0000033293868,0.00015633952],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995497,0.0000065422146,0.000066432796,0.00015799323,0.00010916266,0.000110161054],"domain_scores_gemma":[0.9997815,0.000006014652,0.000043102136,0.0000726673,0.00006116029,0.00003556255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015054502,0.000050745177,0.00005403464,0.000024079687,0.000092567,0.000012926308,0.00005298039,0.000021920327,0.000053232416],"category_scores_gemma":[0.000014380426,0.00004006662,0.000014807403,0.00008452639,0.0001370002,0.000018229835,0.000011105861,0.000015547666,6.246858e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009670656,0.000008932486,0.000025539754,0.000009086984,0.0000019076506,1.4411194e-8,0.00004015291,0.0001132793,0.98030233,0.000023005807,0.000011239451,0.019367816],"study_design_scores_gemma":[0.00025115802,0.00033038633,0.00030021163,0.0000077034165,0.0000023489135,0.0000034496215,0.000053709722,0.00046301723,0.9977352,0.000037173624,0.000758679,0.000056945886],"about_ca_topic_score_codex":0.0000026419564,"about_ca_topic_score_gemma":0.000003938876,"teacher_disagreement_score":0.032869607,"about_ca_system_score_codex":0.0000056754893,"about_ca_system_score_gemma":0.00003876358,"threshold_uncertainty_score":0.16338694},"labels":[],"label_agreement":null},{"id":"W1988880726","doi":"10.1021/jm800400k","title":"Novel Ligands Rationally Designed for Characterizing I<sub>2</sub>−Imidazoline Binding Sites Nature and Functions","year":2008,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Imidazoline receptor; Stereochemistry; Morphine; Aryl; Binding site; Pharmacology; Biochemistry; Organic chemistry","score_opus":0.013527197013739722,"score_gpt":0.2377085015485895,"score_spread":0.22418130453484977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988880726","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98006326,0.0011771162,0.018143415,0.00031718396,0.00017714157,0.00006461377,0.000018788578,0.000004237234,0.000034213983],"genre_scores_gemma":[0.9947177,0.0004850171,0.002327212,0.00023375115,0.0019847162,0.0000050634303,0.00010556521,0.000019698058,0.00012123956],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990736,0.0000068260656,0.00035217538,0.0001726815,0.00022452637,0.00017016049],"domain_scores_gemma":[0.99912494,0.000047359514,0.00030962503,0.00008805807,0.00028603745,0.00014398278],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034860376,0.00014745626,0.00021710063,0.00004197477,0.00017750642,0.000017186312,0.00010665931,0.00025332594,0.000017568163],"category_scores_gemma":[0.0002901564,0.00012557891,0.00011945692,0.00006089936,0.000056285244,0.000012169851,0.000026865444,0.00027507555,3.5596622e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000227727,0.00004286912,0.00026715067,0.000052860767,0.000078518766,0.000010383139,0.00003786997,0.000012802014,0.99801254,0.0000033400556,0.00086701266,0.000386909],"study_design_scores_gemma":[0.0011353361,0.00024100079,0.00028395109,0.000086747976,0.000054515473,0.0014772466,0.000117971875,0.00006058788,0.99493676,0.000013429742,0.0014607647,0.00013168006],"about_ca_topic_score_codex":1.8037889e-7,"about_ca_topic_score_gemma":2.647338e-7,"teacher_disagreement_score":0.015816204,"about_ca_system_score_codex":0.000019222934,"about_ca_system_score_gemma":0.00015679185,"threshold_uncertainty_score":0.5120959},"labels":[],"label_agreement":null},{"id":"W1989019042","doi":"10.1016/j.nlm.2014.01.002","title":"Different roles for M1 and M2 receptors within perirhinal cortex in object recognition and discrimination","year":2014,"lang":"en","type":"article","venue":"Neurobiology of Learning and Memory","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Medical Research Council; Wellcome Trust","keywords":"Perirhinal cortex; Pirenzepine; Neuroscience; Psychology; Muscarinic acetylcholine receptor; Recognition memory; Cognitive neuroscience of visual object recognition; Muscarinic acetylcholine receptor M1; Cholinergic; Cognition; Receptor; Object (grammar); Medicine; Internal medicine; Artificial intelligence; Computer science","score_opus":0.011430877718979215,"score_gpt":0.23255175272322867,"score_spread":0.22112087500424946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989019042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987618,0.000288625,0.00062190474,0.00004056312,0.000117771575,0.00011091135,0.0000034202073,0.000005459163,0.000049559163],"genre_scores_gemma":[0.998922,0.00041155372,0.00033771264,0.000037231486,0.000053473123,0.000011878141,0.00009967148,0.000009901956,0.000116584066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993349,0.00014186681,0.00014390086,0.00024981156,0.000024030136,0.000105500396],"domain_scores_gemma":[0.99976176,0.00005078814,0.00008813219,0.000041670944,0.000025808458,0.000031866148],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025151615,0.00009587788,0.0001526382,0.000046899713,0.000064151056,0.000008000811,0.000024119892,0.00011190757,0.000004896285],"category_scores_gemma":[0.00014212208,0.00008274776,0.000021116924,0.00001490063,0.000086092,0.0000035271264,0.00003106468,0.00009568665,1.3101106e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011959646,0.000014754762,0.005041428,0.000052351574,0.000007168339,9.9869446e-8,0.0003216661,0.000013106993,0.97089535,0.000024045987,0.0000062957124,0.023504134],"study_design_scores_gemma":[0.002045339,0.003872031,0.024677517,0.00011448543,0.000050639057,0.0000372828,0.0018978175,0.0010124249,0.9640906,0.00065023225,0.0012216195,0.00033003755],"about_ca_topic_score_codex":0.0000073667115,"about_ca_topic_score_gemma":0.000023847473,"teacher_disagreement_score":0.023174096,"about_ca_system_score_codex":0.0000021208439,"about_ca_system_score_gemma":0.000006595323,"threshold_uncertainty_score":0.33743557},"labels":[],"label_agreement":null},{"id":"W1989265859","doi":"10.1074/jbc.m201261200","title":"Somatostatin, Acting at Receptor Subtype 1, Inhibits Rho Activity, the Assembly of Actin Stress Fibers, and Cell Migration","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Dental and Craniofacial Research; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Cell biology; Somatostatin receptor; Somatostatin receptor 1; Somatostatin receptor 2; Stress fiber; Somatostatin; Receptor; Biology; Chemistry; Signal transduction; Endocrinology; Biochemistry; Focal adhesion","score_opus":0.01963983086127496,"score_gpt":0.23102374464864964,"score_spread":0.21138391378737467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989265859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99824744,0.00087816827,0.00010681057,0.00023525611,0.000057937206,0.000056982648,0.000014879309,0.0000033192503,0.0003991998],"genre_scores_gemma":[0.99804354,0.0008544843,0.00051868975,0.000037228165,0.00023049489,0.0000016194684,0.000011663914,0.000009227504,0.00029302976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991143,0.000074678064,0.00031851427,0.00017467461,0.00015224873,0.00016562239],"domain_scores_gemma":[0.9989888,0.00008847971,0.0005926463,0.00012729494,0.00012059971,0.00008219678],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002823187,0.0001425887,0.00020810991,0.000012206952,0.00009440552,0.000022778078,0.00016169563,0.00023963855,0.00023710965],"category_scores_gemma":[0.00019861535,0.000088860426,0.0001207504,0.00005608269,0.00007403089,0.000008906551,0.00011210666,0.00020572038,0.0000013590126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010805656,0.00007508455,0.0015537136,0.000039260674,0.000027505657,0.0000018310726,0.0000751075,0.0000130978515,0.99540967,7.1349217e-7,0.000769045,0.0019269241],"study_design_scores_gemma":[0.00031576134,0.0002593671,0.00018593567,0.000041827076,0.000012928835,0.000046261906,0.00028129749,0.000055515033,0.9968365,0.000009348985,0.0018473133,0.000107958986],"about_ca_topic_score_codex":0.0000035643457,"about_ca_topic_score_gemma":0.0000019087133,"teacher_disagreement_score":0.0018189651,"about_ca_system_score_codex":0.000018392018,"about_ca_system_score_gemma":0.000017941207,"threshold_uncertainty_score":0.3623623},"labels":[],"label_agreement":null},{"id":"W1989467245","doi":"10.1385/jmn:26:2-3:209","title":"Adenosine A&lt;SUB&gt;2A&lt;/SUB&gt; and Dopamine D&lt;SUB&gt;2&lt;/SUB&gt; Heteromeric Receptor Complexes and Their Function","year":2005,"lang":"en","type":"review","venue":"Journal of Molecular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":229,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Adenosine; Receptor; Chemistry; Dopamine; Adenosine receptor; Molecular biology; Cell biology; Endocrinology; Biology; Biochemistry","score_opus":0.02072874136628386,"score_gpt":0.25809538725172493,"score_spread":0.23736664588544107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989467245","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18494247,0.80299246,0.008996614,0.00014825423,0.0019244312,0.00078351016,0.000114254086,0.000036215733,0.00006180981],"genre_scores_gemma":[0.08773548,0.90928847,0.00076183135,0.0006199274,0.0011299994,0.000035712816,0.00009651316,0.00020847967,0.00012356704],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99335676,0.0007219792,0.0019387575,0.0017104271,0.0011546296,0.0011174211],"domain_scores_gemma":[0.9955652,0.00010935591,0.0021714666,0.00090605655,0.00047740928,0.00077053753],"candidate_categories":["metaepi_narrow"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0013322281,0.001384664,0.0022926934,0.00062472635,0.00052711496,0.0004990506,0.0011916305,0.00074032607,0.000039630395],"category_scores_gemma":[0.00044368612,0.0011155389,0.0009992385,0.0008906697,0.00061994075,0.000107077714,0.00066466245,0.0009869161,0.000014307593],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008864518,0.00015607069,0.000003192068,0.00057883596,0.00010009254,0.00008995293,0.000019708175,0.00005666595,0.8350556,0.000038368646,0.0006614186,0.16315147],"study_design_scores_gemma":[0.00096637453,0.0023969056,0.000056849593,0.0017190517,0.0004921574,0.002088605,0.000013906238,0.00014983393,0.31512213,0.00004306333,0.6757664,0.0011847274],"about_ca_topic_score_codex":0.0000016283641,"about_ca_topic_score_gemma":0.0000065028744,"teacher_disagreement_score":0.675105,"about_ca_system_score_codex":0.00012088026,"about_ca_system_score_gemma":0.00040698965,"threshold_uncertainty_score":0.9998904},"labels":[],"label_agreement":null},{"id":"W1990164146","doi":"10.1080/08990220801943159","title":"Barrels by the sea: Barrels XX meeting report","year":2008,"lang":"en","type":"article","venue":"Somatosensory & Motor Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Weizmann Institute of Science; University of Sheffield; University of Minnesota; University of Calgary; Carnegie Mellon University; University of Edinburgh; Johns Hopkins University; University of Pennsylvania","keywords":"Barrel (horology); Barrel cortex; Neuroscience; Whisker; Function (biology); Psychology; Cognitive science; Biology; Somatosensory system; Engineering; Chemistry; Evolutionary biology; Mechanical engineering","score_opus":0.0487433366121743,"score_gpt":0.3271462608982433,"score_spread":0.278402924286069,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990164146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907395,0.0036642593,0.00020725165,0.00041701822,0.00024890064,0.0005029851,0.00002573883,0.00003866783,0.0041556256],"genre_scores_gemma":[0.9855553,0.00064228894,0.00038549287,0.00015147385,0.0006493181,0.000094643845,0.00008117725,0.00006950511,0.012370783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99666643,0.0005788586,0.0004050515,0.00065639894,0.00089822477,0.0007950607],"domain_scores_gemma":[0.99831396,0.00011823553,0.00009676832,0.00087600684,0.0003634789,0.000231547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021106964,0.00022415456,0.00022026733,0.00007573399,0.0010193225,0.00006917304,0.0005275241,0.00024085656,0.00020181513],"category_scores_gemma":[0.0007556392,0.00016832074,0.0001857348,0.0002274159,0.00036077714,0.000008416686,0.00029092786,0.00047862605,0.000103225684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046280475,0.000044387227,0.0026325374,0.0000150686665,0.000050340124,0.00014309995,0.00009718831,0.000012359887,0.9657748,0.000060730115,0.030540364,0.00058284035],"study_design_scores_gemma":[0.00030015572,0.00017605083,0.0003081472,0.000024097384,0.0000053064896,0.00069440925,0.00024139593,0.0000844982,0.8753248,0.0001649459,0.12246161,0.00021461259],"about_ca_topic_score_codex":0.00013751791,"about_ca_topic_score_gemma":0.000006232549,"teacher_disagreement_score":0.09192124,"about_ca_system_score_codex":0.000035389017,"about_ca_system_score_gemma":0.0002239193,"threshold_uncertainty_score":0.7839908},"labels":[],"label_agreement":null},{"id":"W1990206527","doi":"10.1016/j.neuropharm.2006.07.020","title":"mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082","year":2006,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Internalization; Agonist; Metabotropic glutamate receptor 7; G protein-coupled receptor; Metabotropic glutamate receptor; Allosteric regulation; Cell biology; Neuroscience; Chemistry; Biology; Receptor; Signal transduction; Biochemistry","score_opus":0.007483067908964923,"score_gpt":0.2543356137299127,"score_spread":0.2468525458209478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990206527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907905,0.00010015599,0.006372677,0.0019220166,0.00035677032,0.00022899466,0.0000052047244,0.000011754305,0.00021195655],"genre_scores_gemma":[0.9950493,0.000046128738,0.00006091057,0.0034573285,0.00017492124,0.000040117462,0.000046229277,0.000021825352,0.0011032262],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988886,0.0003730767,0.00019371333,0.00027009528,0.00008234547,0.00019213783],"domain_scores_gemma":[0.9996752,0.00005596623,0.00006712676,0.00013072352,0.00003658241,0.00003437538],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020236838,0.00011479131,0.00009026754,0.000056819033,0.00007178372,0.000028113875,0.00018129036,0.000077827455,0.0001232223],"category_scores_gemma":[0.00006050119,0.00009508023,0.00003680568,0.00013803429,0.000031823656,0.0000046250484,0.0000803462,0.000091593254,0.00001565157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00087857293,0.000045574754,0.00016125667,0.000002620402,0.000006749724,0.000004584707,0.000018521154,0.00073156157,0.9876588,0.000045928322,0.009507365,0.00093844277],"study_design_scores_gemma":[0.00053564174,0.00033262454,0.0011419964,0.0000034237821,0.0000058360833,0.000007305659,0.000014800605,0.00015601398,0.90495145,0.00004745338,0.092703275,0.000100199475],"about_ca_topic_score_codex":0.000055073157,"about_ca_topic_score_gemma":0.000016012787,"teacher_disagreement_score":0.08319591,"about_ca_system_score_codex":0.00002574698,"about_ca_system_score_gemma":0.00003099274,"threshold_uncertainty_score":0.3877259},"labels":[],"label_agreement":null},{"id":"W1990218497","doi":"10.1111/j.1749-6632.2002.tb04760.x","title":"Na<sup>+</sup>/Ca<sup>2+</sup> Exchange in Activated and Nonactivated Human Platelets","year":2002,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Citation; Library science; Gerontology; Medicine; Computer science","score_opus":0.06698814232613101,"score_gpt":0.3035333782050325,"score_spread":0.2365452358789015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990218497","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947877,0.0020522538,0.000015240155,0.002352419,0.000023756082,0.00019298609,0.000011293104,0.000007610385,0.00055677415],"genre_scores_gemma":[0.99768984,0.00061184086,0.00019926805,0.0007173645,0.000115277966,0.0000048052343,0.0000028799154,0.000013023481,0.0006456917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832314,0.000117336895,0.00037752197,0.00044067498,0.00035601453,0.00038531085],"domain_scores_gemma":[0.9994342,0.000041075196,0.00024113258,0.00013595315,0.00003720934,0.0001104765],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065392884,0.00020345185,0.00029163712,0.00012792146,0.00019901957,0.000027432749,0.0006651593,0.00027488798,0.00020939906],"category_scores_gemma":[0.000088571294,0.00014880286,0.00011038103,0.00047386426,0.00040859706,0.000028177257,0.00020351003,0.00021655865,0.0000029347111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036703546,0.00008106859,0.00039809707,0.000029050583,0.000038105038,4.140762e-7,0.0010221278,0.0031379054,0.9836604,0.00015746172,0.006168523,0.005270115],"study_design_scores_gemma":[0.00039470513,0.00024638753,0.0003384212,0.00012813523,0.000007873646,0.000006724182,0.00043779027,0.004120005,0.9876706,0.00086322386,0.005593883,0.00019222221],"about_ca_topic_score_codex":0.00016854417,"about_ca_topic_score_gemma":0.0000022755066,"teacher_disagreement_score":0.005077893,"about_ca_system_score_codex":0.000005529596,"about_ca_system_score_gemma":0.000025422043,"threshold_uncertainty_score":0.6068005},"labels":[],"label_agreement":null},{"id":"W1990264028","doi":"10.1074/jbc.m114.561449","title":"The Molecular Basis of Ligand Interaction at Free Fatty Acid Receptor 4 (FFA4/GPR120)","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research","keywords":"GPR120; Chemistry; Ligand (biochemistry); Fatty acid; Free fatty acid receptor; Biochemistry; Receptor; G protein-coupled receptor; Polyunsaturated fatty acid","score_opus":0.011701140734766394,"score_gpt":0.23632553195629813,"score_spread":0.22462439122153174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990264028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99421835,0.0012219156,0.003311883,0.00025055645,0.00022985894,0.00004167334,0.000008205016,0.0000037343902,0.0007138455],"genre_scores_gemma":[0.9974325,0.00061190594,0.0012894408,0.000092103815,0.000430364,0.0000025957972,0.00001566264,0.000010742542,0.00011472784],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988783,0.000083442,0.00048335863,0.00018286557,0.0001814975,0.00019051324],"domain_scores_gemma":[0.99881643,0.00006469805,0.0005162838,0.00029615592,0.00020048564,0.000105962055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059383246,0.0001522852,0.0002438627,0.000012050917,0.000095532174,0.000021478041,0.00043797705,0.00026834258,0.00014795411],"category_scores_gemma":[0.0007595981,0.000089714245,0.000287314,0.000052869415,0.00011088162,0.000004414557,0.00018157205,0.00020680255,0.0000029164692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026583776,0.000038919625,0.00037624172,0.000014097806,0.000067663175,0.0000017443872,0.0000087833305,0.000018669116,0.9960041,0.000025491256,0.0009504821,0.0022279369],"study_design_scores_gemma":[0.00039038158,0.00039125854,0.00009532711,0.00002963145,0.00001656517,0.00006068153,0.00007324302,0.000015872174,0.97467405,0.00026373673,0.02387917,0.00011007401],"about_ca_topic_score_codex":0.0000010355074,"about_ca_topic_score_gemma":4.9341935e-7,"teacher_disagreement_score":0.022928689,"about_ca_system_score_codex":0.000027626873,"about_ca_system_score_gemma":0.000026683601,"threshold_uncertainty_score":0.36584407},"labels":[],"label_agreement":null},{"id":"W1990461661","doi":"10.1016/j.drudis.2008.09.002","title":"Physiological relevance of GPCR oligomerization and its impact on drug discovery","year":2008,"lang":"en","type":"review","venue":"Drug Discovery Today","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Military College of Canada; AstraZeneca (Canada)","funders":"Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"G protein-coupled receptor; Druggability; Drug discovery; Computational biology; Biology; Receptor; Drug development; Drug; Bioinformatics; Pharmacology; Biochemistry; Gene","score_opus":0.017807354554553574,"score_gpt":0.2962509539751557,"score_spread":0.27844359942060215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990461661","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07118087,0.92730445,0.00017844296,0.000007819907,0.00028482592,0.00046608315,0.00038278507,0.000011693749,0.00018305515],"genre_scores_gemma":[0.053402565,0.9432218,0.00003329817,0.00004379463,0.00036798848,0.00004253801,0.0010904657,0.00006511441,0.0017324347],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978814,0.0002281432,0.0005588823,0.0007553701,0.00023954496,0.00033664418],"domain_scores_gemma":[0.998863,0.00007801224,0.00047824904,0.00044192476,0.000046069923,0.00009276187],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013861102,0.00057106663,0.0012165067,0.00008724163,0.00009445929,0.000061446,0.00029943578,0.0003131693,0.000025180872],"category_scores_gemma":[0.00011090109,0.00038398532,0.0006619695,0.00016240068,0.000085821586,0.000034351822,0.00018684071,0.00024750194,0.000010300542],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00090603065,0.0017222597,0.000055604745,0.019865634,0.0026337046,0.000089654925,0.00053732446,0.0023346108,0.44836083,0.004788608,0.022246597,0.49645913],"study_design_scores_gemma":[0.00090026506,0.0010692694,0.00007327521,0.00938299,0.00043301244,0.00009594492,0.00007277072,0.000065795655,0.10018767,0.00023948801,0.88522995,0.0022495773],"about_ca_topic_score_codex":0.000013060154,"about_ca_topic_score_gemma":0.0000014123161,"teacher_disagreement_score":0.86298335,"about_ca_system_score_codex":0.00003789596,"about_ca_system_score_gemma":0.00018731708,"threshold_uncertainty_score":0.9998612},"labels":[],"label_agreement":null},{"id":"W1990603703","doi":"10.1016/j.cellsig.2006.05.026","title":"Ligand-specific receptor states: Implications for opiate receptor signalling and regulation","year":2006,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Louis-H Lafontaine","funders":"Canadian Institutes of Health Research","keywords":"Opiate; G protein-coupled receptor; Receptor; Ligand (biochemistry); Signalling; μ-opioid receptor; Pharmacology; Medicine; Biology; Bioinformatics; Opioid; Internal medicine; Cell biology","score_opus":0.03714676833424422,"score_gpt":0.28082772451634835,"score_spread":0.24368095618210414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990603703","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00038306337,0.7672327,0.23031235,0.00002222852,0.00035374984,0.0013395231,0.000256877,0.000048457132,0.000051033905],"genre_scores_gemma":[0.00025676982,0.9725089,0.011998827,0.000027616055,0.0017366486,0.00045645007,0.011355402,0.0002483541,0.0014110391],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966015,0.0001622116,0.001127062,0.001285179,0.00019487497,0.000629151],"domain_scores_gemma":[0.9981745,0.0001481697,0.0007146249,0.00050902896,0.0002565275,0.00019716873],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007321716,0.0007532477,0.0011893122,0.00020221343,0.0004515956,0.00023898142,0.00041820612,0.00083066523,0.000080961414],"category_scores_gemma":[0.00003621619,0.0007323508,0.00067013165,0.00024194075,0.000080147525,0.0000149149955,0.00012283433,0.0003012676,0.000028854105],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033941695,0.00006851131,0.0000014804477,0.0037689242,0.0002620481,7.1079495e-7,0.00003580506,0.00056476187,0.7061412,0.001014097,0.0035960227,0.2845125],"study_design_scores_gemma":[0.00031134675,0.00017441706,1.2611366e-7,0.0020566545,0.00026181925,0.0000052700066,0.000016150985,0.00015993044,0.061568867,0.0005510943,0.9340815,0.0008128457],"about_ca_topic_score_codex":0.000006693558,"about_ca_topic_score_gemma":0.0000019047493,"teacher_disagreement_score":0.9304854,"about_ca_system_score_codex":0.00007322451,"about_ca_system_score_gemma":0.00019663245,"threshold_uncertainty_score":0.99951273},"labels":[],"label_agreement":null},{"id":"W1990693523","doi":"10.1196/annals.1304.035","title":"Normalization of Up‐Regulated Cardiac Imidazoline I<sub>1</sub>‐Receptors and Natriuretic Peptides by Chronic Treatment with Moxonidine in Spontaneously Hypertensive Rats","year":2003,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Heart and Stroke Foundation of Canada","keywords":"Moxonidine; Atrial natriuretic peptide; Imidazoline receptor; Internal medicine; Receptor; Endocrinology; Natriuretic peptide; Brain natriuretic peptide; Agonist; Medicine; NPR2; Chemistry; Heart failure","score_opus":0.02020823131271718,"score_gpt":0.2514831209040174,"score_spread":0.23127488959130024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990693523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898344,0.009508486,0.000025276775,0.00033020898,0.000053422675,0.00020317682,0.000009823028,0.0000022358226,0.000032964457],"genre_scores_gemma":[0.99593496,0.0037598126,0.00013050596,0.00006497052,0.000028887549,0.0000030514136,0.000004831789,0.000008037785,0.000064942986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989725,0.00008700772,0.00027925466,0.0002487111,0.00021752012,0.00019501195],"domain_scores_gemma":[0.9995303,0.000025425155,0.00025207788,0.00007615425,0.000061178755,0.000054821354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031791595,0.00014291344,0.00027814793,0.00006288594,0.00006353482,0.0000076074725,0.00017028577,0.0001173227,0.0000052817018],"category_scores_gemma":[0.000040053186,0.0000906601,0.00007676284,0.00030904292,0.00033072382,0.000010312061,0.000028189734,0.000050724746,1.5687395e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057243145,0.00002461293,0.0007385372,0.000014617178,0.00004132077,1.3994763e-7,0.00011231076,0.0016922065,0.99528736,0.0001515861,0.00053513556,0.001344956],"study_design_scores_gemma":[0.00030233015,0.00077421585,0.00023400632,0.000084546686,0.000025168763,0.000010297315,0.000172064,0.00013186938,0.9973155,0.00022792678,0.00061945256,0.00010261658],"about_ca_topic_score_codex":0.00007515618,"about_ca_topic_score_gemma":0.000014639219,"teacher_disagreement_score":0.006100554,"about_ca_system_score_codex":0.000009418624,"about_ca_system_score_gemma":0.00012493666,"threshold_uncertainty_score":0.36970115},"labels":[],"label_agreement":null},{"id":"W1990713809","doi":"10.1002/jps.10381","title":"Disease–drug interaction: Reduced response to propranolol despite increased concentration in the rat with inflammation","year":2003,"lang":"en","type":"article","venue":"Journal of Pharmaceutical Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Propranolol; Sotalol; Atenolol; Pharmacokinetics; Pharmacology; Medicine; Bioavailability; Clearance; Internal medicine; Endocrinology; Drug; Inflammation; Ramipril; Oral administration; Chemistry; Blood pressure","score_opus":0.026159413120745535,"score_gpt":0.33554407045774776,"score_spread":0.3093846573370022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990713809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99586886,0.0001609999,0.0013668269,0.0021869165,0.00014333853,0.0001621963,4.3081306e-7,0.0000013344217,0.00010909384],"genre_scores_gemma":[0.99859494,0.0000310129,0.0008270845,0.00041429108,0.00010936223,0.000005588852,6.21866e-7,0.0000026421028,0.0000144625765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876493,0.00048042336,0.00021572839,0.0001137997,0.00029265706,0.00013248173],"domain_scores_gemma":[0.9995674,0.000060261158,0.000110274574,0.000055162953,0.00009303117,0.000113859736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021225945,0.0000659724,0.00006964475,0.000043963806,0.00009384545,0.00007652652,0.00015824134,0.000020035714,0.00004857119],"category_scores_gemma":[0.00039438705,0.00003657569,0.00003408242,0.0002220914,0.000071309514,0.000026559832,0.000008755134,0.000103031525,0.0000015107012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016099138,0.000033407574,0.0011598269,0.0000033329684,0.000005835134,0.000010667328,0.000175914,0.0009882278,0.9948565,0.00019602418,0.000076588265,0.0008837853],"study_design_scores_gemma":[0.0005934788,0.00047491468,0.0011260292,0.000045266137,0.000016550586,0.00006137944,0.00049767253,0.00032764723,0.98033786,0.000095319054,0.016345413,0.00007847975],"about_ca_topic_score_codex":0.0000014748193,"about_ca_topic_score_gemma":0.0000032197834,"teacher_disagreement_score":0.016268825,"about_ca_system_score_codex":0.000019982705,"about_ca_system_score_gemma":0.00020915273,"threshold_uncertainty_score":0.14915133},"labels":[],"label_agreement":null},{"id":"W1991105330","doi":"10.1124/mol.107.034884","title":"Desensitization of the Dopamine D1 and D2 Receptor Hetero-Oligomer Mediated Calcium Signal by Agonist Occupancy of Either Receptor","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse","keywords":"Agonist; Desensitization (medicine); Homologous desensitization; Dopamine receptor D2; Chemistry; Receptor; Calcium; Endocrinology; Pharmacology; Internal medicine; Biophysics; Biochemistry; Biology; Medicine","score_opus":0.007364896375458016,"score_gpt":0.25985174825544877,"score_spread":0.25248685187999076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991105330","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824043,0.0010905699,0.015258908,0.00016091869,0.000527616,0.00030904444,0.00007990348,0.000009007078,0.00015975296],"genre_scores_gemma":[0.99814445,0.00012381062,0.0006523409,0.0005355502,0.00014468447,0.000010537988,0.00016971887,0.0000368202,0.00018211851],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985761,0.0001958095,0.00040875468,0.00032872692,0.00018618097,0.0003044245],"domain_scores_gemma":[0.9992408,0.000034958528,0.00025623047,0.00019234407,0.00017598402,0.00009968316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038322769,0.00019934052,0.00025894368,0.000058048023,0.00006743244,0.000006725587,0.00019104357,0.0002304306,0.0003528029],"category_scores_gemma":[0.00004195783,0.0001641548,0.00011294552,0.00017363662,0.00022268928,0.000004603532,0.00012608529,0.00012566274,0.00000387297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021654478,0.000087942244,0.0006005301,0.000029758143,0.00012554538,0.000002540779,0.00004455592,0.000024237896,0.9950396,0.000030243975,0.0028713637,0.00092718255],"study_design_scores_gemma":[0.00087394274,0.0002666616,0.00013623087,0.0000116758765,0.0000560323,0.000008613116,0.00003784172,0.000058371195,0.97883874,0.000010580055,0.019537563,0.00016374],"about_ca_topic_score_codex":0.000027505657,"about_ca_topic_score_gemma":0.0000031821332,"teacher_disagreement_score":0.016666198,"about_ca_system_score_codex":0.000016778795,"about_ca_system_score_gemma":0.000050538012,"threshold_uncertainty_score":0.66940385},"labels":[],"label_agreement":null},{"id":"W1991403224","doi":"10.1016/j.ejphar.2006.11.058","title":"Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2","year":2006,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Merck Canada Inc. (Canada); Université de Sherbrooke","funders":"","keywords":"Internalization; G protein-coupled receptor kinase; Receptor; Homologous desensitization; Prostanoid; Prostaglandin E2 receptor; Cell biology; G protein-coupled receptor; Prostaglandin D2; Protease-activated receptor 2; Beta adrenergic receptor kinase; Enzyme-linked receptor; Biology; Chemistry; Signal transduction; Agonist; Biochemistry","score_opus":0.00717175602217421,"score_gpt":0.2288750113376575,"score_spread":0.2217032553154833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991403224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997289,0.0006133889,0.00089198665,0.00018914518,0.00075143325,0.00017275415,0.000006856254,0.000001930717,0.00008349312],"genre_scores_gemma":[0.9987715,0.0000793863,0.00039734054,0.000042364292,0.0005421001,7.22867e-7,0.0000041972385,0.000019363359,0.00014305467],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985459,0.00057085743,0.00047009112,0.00013709691,0.00014384578,0.00013220911],"domain_scores_gemma":[0.99907786,0.000024320228,0.0006502896,0.00008518113,0.00012966045,0.000032671338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053941185,0.000116562675,0.0001818026,0.000039057584,0.00010013348,0.000013646743,0.00018150012,0.000038188115,0.000092584276],"category_scores_gemma":[0.000029130124,0.000070848495,0.00010063125,0.00007295194,0.00015847162,0.000007536007,0.00011289219,0.00015444691,1.8154877e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018675662,0.00003984693,0.0019546715,0.000025283736,0.00004594216,8.605969e-7,0.00015919891,0.0003352461,0.99492943,0.000063802254,0.0008651627,0.0013938096],"study_design_scores_gemma":[0.0013952056,0.00028985663,0.0035645433,0.000052933778,0.000071594775,0.000039481096,0.0000584175,0.00007144418,0.9905216,0.000036900237,0.003819988,0.00007801952],"about_ca_topic_score_codex":0.0000026194384,"about_ca_topic_score_gemma":0.000001820417,"teacher_disagreement_score":0.0044078035,"about_ca_system_score_codex":0.000008688213,"about_ca_system_score_gemma":0.00003888873,"threshold_uncertainty_score":0.28891176},"labels":[],"label_agreement":null},{"id":"W1991791520","doi":"10.1038/ncomms5556","title":"Gαs regulates the post-endocytic sorting of G protein-coupled receptors","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Missouri University of Science and Technology; University of Illinois at Urbana-Champaign; Northwestern University","keywords":"Endosome; G protein-coupled receptor; ESCRT; Endocytic cycle; Cell biology; Internalization; Retromer; Receptor; Transport protein; G protein; Biology; Signal transduction; Endocytosis; Intracellular; Chemistry; Biochemistry","score_opus":0.009231153677581965,"score_gpt":0.25874381348623066,"score_spread":0.2495126598086487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991791520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864031,0.0065484024,0.000870564,0.0028511905,0.00021874039,0.0005565265,0.000008129884,0.000031036165,0.0025123297],"genre_scores_gemma":[0.9939155,0.00012801788,0.0052055637,0.00022821875,0.0000825219,0.00004001119,0.00013612163,0.000016780763,0.00024726],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923444,0.00015593298,0.00022653797,0.00014362654,0.00010550536,0.0001339657],"domain_scores_gemma":[0.9981367,0.00007142802,0.00017574198,0.0013516535,0.00023317388,0.000031308933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042202018,0.000097242875,0.00011029691,0.000026602078,0.00023748529,0.000018128383,0.0008437637,0.00020203607,0.000028400551],"category_scores_gemma":[0.0005166838,0.00007005355,0.00008456692,0.00010663374,0.000107383465,0.000003418377,0.00026342494,0.00032578112,0.000004182913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011243989,0.000027275308,0.00015065157,0.000006967186,0.000029661964,1.9439176e-8,0.00007001008,0.000024286488,0.9847236,0.0132909715,0.00017277837,0.001492512],"study_design_scores_gemma":[0.0002980013,0.00016726514,0.0003614013,0.000042256324,0.000031763448,0.00000550616,0.0002784257,0.0020413413,0.92410266,0.00096221257,0.071525656,0.00018348363],"about_ca_topic_score_codex":0.00001745714,"about_ca_topic_score_gemma":0.00007582364,"teacher_disagreement_score":0.07135288,"about_ca_system_score_codex":0.000008062093,"about_ca_system_score_gemma":0.000041610863,"threshold_uncertainty_score":0.2856701},"labels":[],"label_agreement":null},{"id":"W1992155036","doi":"10.1159/000138493","title":"Pressor Response to β <sub>1</sub> - and β <sub>2</sub> -Blockers in Conscious Rats Treated with Phentolamine","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; British Heart Foundation","keywords":"Phentolamine; Atenolol; Propranolol; Endocrinology; Internal medicine; BETA (programming language); Antagonist; Bolus (digestion); Chemistry; Blockade; Medicine; Blood pressure; Receptor","score_opus":0.009790456524758379,"score_gpt":0.24356386227422144,"score_spread":0.23377340574946306,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992155036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99795914,0.00058812636,0.00019400327,0.00047580112,0.00015920734,0.00053676934,0.000021765733,0.000027489587,0.000037693568],"genre_scores_gemma":[0.9978788,0.0005489131,0.00024951895,0.000899156,0.00014062958,0.00013188935,0.000039064296,0.000040601768,0.00007145886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830043,0.00028006666,0.00026305925,0.000562405,0.00012290002,0.00047111884],"domain_scores_gemma":[0.9993731,0.00006143878,0.00008478791,0.00017383647,0.000085640306,0.00022124402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000269269,0.00026423673,0.0002988928,0.00014438081,0.00012304955,0.000013171936,0.00014303507,0.00018245981,0.000032725595],"category_scores_gemma":[0.00004646651,0.00024373933,0.00004641823,0.00019278137,0.00014987557,0.0000075045186,0.000104731516,0.00015635944,0.000013898651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005193921,0.00012176524,0.001126326,0.000011989404,0.000088292145,0.00020571811,0.00019108283,0.00014846478,0.9883119,0.0000026092857,0.0035129709,0.0010849454],"study_design_scores_gemma":[0.0027133366,0.0010036906,0.0011517059,0.000013332217,0.000045530065,0.00017461948,0.00004046217,0.00014366626,0.9909191,0.000006047256,0.00349264,0.00029585985],"about_ca_topic_score_codex":0.000016524722,"about_ca_topic_score_gemma":0.00004875866,"teacher_disagreement_score":0.0026071945,"about_ca_system_score_codex":0.000033476954,"about_ca_system_score_gemma":0.00011182024,"threshold_uncertainty_score":0.9939401},"labels":[],"label_agreement":null},{"id":"W1992168773","doi":"10.1016/j.bpj.2014.06.016","title":"New Pipelines for Novel Allosteric GPCR Modulators","year":2014,"lang":"en","type":"letter","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Process Research Ortech (Canada); University of Toronto","funders":"","keywords":"G protein-coupled receptor; Allosteric regulation; Computational biology; Receptor; Agonism; Scopus; Chemistry; Drug discovery; Bioinformatics; Biology; Neuroscience; Biochemistry; MEDLINE; Political science","score_opus":0.0205126239354905,"score_gpt":0.25212044144269796,"score_spread":0.23160781750720746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992168773","genre_codex":"methods","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011598639,0.00021933742,0.8638706,0.120014966,0.0035952602,0.0004494966,0.00008639947,0.000028816006,0.00013648825],"genre_scores_gemma":[0.025269339,0.00018965174,0.05297281,0.64680666,0.2595176,0.000046427132,0.0013775121,0.00044796115,0.013372017],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983475,0.0000400834,0.0003920523,0.00045374592,0.0002945661,0.0004720521],"domain_scores_gemma":[0.9990133,0.000025560952,0.0003043047,0.00030348694,0.00016789716,0.00018546918],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00013500024,0.00038650713,0.00041703027,0.00006307891,0.0001363083,0.0001451678,0.00044760652,0.000790921,0.00007716091],"category_scores_gemma":[0.000050283008,0.00031737162,0.0006109584,0.000053034233,0.000032211003,0.000004381535,0.00008214246,0.00068824604,0.000022398415],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024654582,0.000012553509,6.364277e-7,0.000019333414,0.0000651282,0.0000046610376,0.0000029670382,0.000014986655,0.5342597,0.00001445341,0.4643392,0.0012417325],"study_design_scores_gemma":[0.0005886306,0.00041925788,0.0000022315107,0.00004381373,0.00007005107,0.0001241181,0.000002727525,0.0002639502,0.1705077,0.00021276786,0.82737255,0.00039216672],"about_ca_topic_score_codex":0.000005680473,"about_ca_topic_score_gemma":3.5238938e-7,"teacher_disagreement_score":0.81089777,"about_ca_system_score_codex":0.000021884607,"about_ca_system_score_gemma":0.00014730608,"threshold_uncertainty_score":0.9999278},"labels":[],"label_agreement":null},{"id":"W1992276619","doi":"10.1186/1756-6606-4-20","title":"GPCR oligomers in pharmacology and signaling","year":2011,"lang":"en","type":"review","venue":"Molecular Brain","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Institute of Mental Health; University of Toronto; Centre for Addiction and Mental Health","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Internalization; Receptor; Signal transduction; Function (biology); G protein; Effector; Intracellular; Neuroscience; Computational biology; Cell biology; Biology; Chemistry; Biochemistry","score_opus":0.022698781614427014,"score_gpt":0.30789688824976996,"score_spread":0.28519810663534295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992276619","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002349359,0.9953019,0.0011321666,0.000018909417,0.00024310607,0.00047925516,0.000012022613,0.000012377222,0.0004508741],"genre_scores_gemma":[0.00052388536,0.9975344,0.00071536633,0.00044343402,0.00016409777,0.000109147644,0.00017060389,0.000100594356,0.00023845295],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980206,0.00033304095,0.0004469518,0.00069266534,0.000091646216,0.00041510622],"domain_scores_gemma":[0.99937546,0.000027291235,0.00017553092,0.00026940615,0.000024814919,0.00012748278],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042047634,0.00042983904,0.0008247224,0.00019977582,0.000042325817,0.000025205269,0.0002812923,0.0005651301,0.00014476139],"category_scores_gemma":[0.000047157253,0.000414256,0.0002872947,0.00016446672,0.00006765208,0.0000024496892,0.00020511272,0.0003003796,0.000016582679],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016967562,0.00006511434,0.0000039233396,0.0026768656,0.00032369862,0.00017291635,0.00007311525,0.00000894188,0.38893896,0.00040426574,0.00094030326,0.6063749],"study_design_scores_gemma":[0.00032805518,0.00011467421,2.3159765e-7,0.00079271017,0.00016109005,0.00006418157,0.00001431596,0.0000035274088,0.036814686,0.00009225509,0.96110344,0.00051081437],"about_ca_topic_score_codex":0.000014380058,"about_ca_topic_score_gemma":0.0000054424636,"teacher_disagreement_score":0.9601632,"about_ca_system_score_codex":0.000024167022,"about_ca_system_score_gemma":0.00013561455,"threshold_uncertainty_score":0.9998309},"labels":[],"label_agreement":null},{"id":"W1992532480","doi":"10.1159/000137489","title":"Distribution of Muscarinic Receptors in the Digestive Tract Organs","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Medical Research Council Canada; F. Hoffmann-La Roche","keywords":"Muscarinic acetylcholine receptor; Quinuclidinyl Benzilate; Endocrinology; Antrum; Internal medicine; Muscarinic acetylcholine receptor M1; Receptor; Population; Biology; Muscarinic acetylcholine receptor M2; Muscarinic antagonist; Pirenzepine; Antagonist; Stomach; Chemistry; Biochemistry; Medicine","score_opus":0.01842595584123982,"score_gpt":0.28102956596249534,"score_spread":0.26260361012125555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992532480","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981435,0.0002892089,0.0005972489,0.00017894447,0.00034485818,0.00014339137,0.000013300245,0.000004072829,0.00028545872],"genre_scores_gemma":[0.9989732,0.0004242194,0.000043856973,0.00019621951,0.00015564631,0.000021584532,0.000115357594,0.0000071762406,0.000062746294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930775,0.00013735033,0.00016610016,0.00015977035,0.00007049723,0.00015851893],"domain_scores_gemma":[0.9997486,0.0000334419,0.000065766166,0.000090546186,0.000036961,0.000024681873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020307898,0.0000810792,0.000108368906,0.00002027281,0.000052282692,0.0000018122008,0.00016349455,0.00008808071,0.00023135275],"category_scores_gemma":[0.000031500178,0.00006189962,0.000055492324,0.000107369924,0.00008208432,0.0000025268425,0.000029682846,0.00010684973,0.000005408635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065440516,0.00016768435,0.007414398,0.0000050917133,0.000021984335,0.000009536111,0.0003880072,0.00013075508,0.98755974,0.000072179224,0.0034175443,0.0007476339],"study_design_scores_gemma":[0.0006438686,0.00032396946,0.017090566,0.0000030336023,0.000020843667,0.000052262883,0.00018949063,0.00005636315,0.95201886,0.000040384257,0.029453704,0.00010667145],"about_ca_topic_score_codex":0.000026724689,"about_ca_topic_score_gemma":0.0000038783596,"teacher_disagreement_score":0.035540905,"about_ca_system_score_codex":0.000012087221,"about_ca_system_score_gemma":0.00004843013,"threshold_uncertainty_score":0.25331503},"labels":[],"label_agreement":null},{"id":"W1992719972","doi":"10.1097/00001756-200206120-00007","title":"Dopamine D2 receptors internalize in their low-affinity state","year":2002,"lang":"en","type":"article","venue":"Neuroreport","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dopamine receptor D2; Internalization; Sulpiride; Dopamine; Dopamine receptor; Receptor; Chemistry; D2-like receptor; Endocrinology; Internal medicine; Dopamine receptor D1; Biology; Biochemistry; Antagonist; Medicine","score_opus":0.016507277959334717,"score_gpt":0.22497294681555566,"score_spread":0.20846566885622095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992719972","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99557453,0.00019206587,0.0004167794,0.000069856054,0.00057287875,0.000120976525,0.0000049825226,0.000021350212,0.0030265914],"genre_scores_gemma":[0.9962633,0.00024758553,0.00014273086,0.00030626068,0.0001409169,0.000014118573,0.000026988751,0.000030531217,0.002827551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880755,0.00005653173,0.0003570804,0.00039038787,0.00013014414,0.00025827906],"domain_scores_gemma":[0.99940103,0.000009572725,0.00012844648,0.0003339727,0.000042402866,0.00008456217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001965891,0.00017034516,0.00016655518,0.000053948097,0.000032637538,0.000025487563,0.00017218696,0.000083841485,0.00068530615],"category_scores_gemma":[0.000095543306,0.0001496413,0.00009486967,0.00010221254,0.000032608375,0.0000053113918,0.00009512911,0.0001481983,0.000028570123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004226135,0.00014550738,0.011416822,0.000013133585,0.000020307998,0.00015415995,0.00012042622,0.0001559824,0.9751011,0.000011712508,0.0026849152,0.010133634],"study_design_scores_gemma":[0.00041415356,0.0002478031,0.0014097174,0.00002084818,0.0000036282738,0.00009934327,0.0000311917,0.00035239776,0.93521947,0.00010998366,0.061851144,0.00024033824],"about_ca_topic_score_codex":0.000026686606,"about_ca_topic_score_gemma":0.00001895078,"teacher_disagreement_score":0.05916623,"about_ca_system_score_codex":0.000011775748,"about_ca_system_score_gemma":0.00001683138,"threshold_uncertainty_score":0.7503622},"labels":[],"label_agreement":null},{"id":"W1992739435","doi":"10.1159/000094084","title":"Tracing the Evolution and Function of the Trk Superfamily of Receptor Tyrosine Kinases","year":2006,"lang":"en","type":"review","venue":"Brain Behavior and Evolution","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Trk receptor; Receptor tyrosine kinase; Biology; Tropomyosin receptor kinase C; Receptor Protein-Tyrosine Kinases; ROR1; Receptor; Cell biology; Tyrosine kinase; Functional divergence; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Platelet-derived growth factor receptor; Biochemistry; Neurotrophin; Gene; Gene family; Genome","score_opus":0.01894054576994953,"score_gpt":0.26194538512468846,"score_spread":0.24300483935473893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992739435","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.106553584,0.8915741,0.0009071009,0.000014280148,0.00030398986,0.00051920675,0.000094060975,0.000006917035,0.000026795213],"genre_scores_gemma":[0.34049863,0.65806514,0.0001174904,0.000013030822,0.00034815352,0.00010023832,0.00031962647,0.000044521687,0.0004931473],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988252,0.00018701018,0.00040866318,0.00028453802,0.00014905231,0.00014555104],"domain_scores_gemma":[0.9993061,0.00003323319,0.0002970282,0.00026177164,0.00007503885,0.000026866488],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003297333,0.00021530746,0.00040029822,0.0000541601,0.00015733868,0.0000137309435,0.00011584237,0.00030783875,0.000008869832],"category_scores_gemma":[0.000051144027,0.0001305648,0.00022270124,0.0001498111,0.0001550824,0.000006703044,0.000073776035,0.00013143348,3.7160152e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007668383,0.00020077988,0.0014383113,0.0036118047,0.000098687495,3.0609212e-7,0.00005952389,0.00001512725,0.3872426,0.0010307638,0.0036712561,0.6025542],"study_design_scores_gemma":[0.002466768,0.0027657454,0.067194134,0.01331255,0.0075896336,0.00021154019,0.0010907531,0.00010287257,0.04052633,0.00051794125,0.86203873,0.00218298],"about_ca_topic_score_codex":0.00024198338,"about_ca_topic_score_gemma":0.00003504723,"teacher_disagreement_score":0.8583675,"about_ca_system_score_codex":0.000041629708,"about_ca_system_score_gemma":0.00009385104,"threshold_uncertainty_score":0.5324278},"labels":[],"label_agreement":null},{"id":"W1992750772","doi":"10.1097/01.lab.0000029207.92039.2f","title":"Angiotensin II's Antiproliferative Effects Mediated Through AT2-Receptors Depend On Down-Regulation of SM-20","year":2002,"lang":"en","type":"article","venue":"Laboratory Investigation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Deutsche Forschungsgemeinschaft; University of Ottawa; American Society of Nephrology","keywords":"Angiotensin II; Receptor; Molecular biology; Blot; Vascular smooth muscle; Losartan; Biology; Apoptosis; Cell culture; Polyclonal antibodies; Cell biology; Endocrinology; Gene; Antibody; Biochemistry; Immunology","score_opus":0.01168565038475826,"score_gpt":0.2152283146906829,"score_spread":0.20354266430592463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992750772","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99734557,0.00041010708,0.0010535604,0.00024102163,0.0003688675,0.0003055389,0.000040926123,0.000029919816,0.00020447513],"genre_scores_gemma":[0.9963916,0.000038455993,0.0020563386,0.0006768485,0.00024105812,0.000017861465,0.00041850284,0.000028629831,0.00013070353],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876404,0.00018057541,0.00028258923,0.00034441924,0.00024328957,0.00018509319],"domain_scores_gemma":[0.9991635,0.00002832403,0.00021740366,0.0002505031,0.00025464298,0.000085625914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016699305,0.00019935702,0.00019786257,0.000058187896,0.00014355444,0.000018301444,0.000097363416,0.0002504191,0.00016247346],"category_scores_gemma":[0.00021098916,0.00018884841,0.000059876445,0.00029749435,0.00009122916,0.000024146224,0.00003248888,0.00009771945,0.00002842403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026523938,0.000042888914,0.0007360854,0.000020662548,0.00004181871,8.1978743e-7,0.0004547582,0.00042030402,0.9943022,0.00086649234,0.0027814785,0.00030594526],"study_design_scores_gemma":[0.0005238622,0.0005406307,0.0010143355,0.000058289097,0.00002158547,8.4015994e-7,0.000032197793,0.0010575864,0.9920658,0.0004466824,0.00403742,0.00020079772],"about_ca_topic_score_codex":0.000010504817,"about_ca_topic_score_gemma":0.000009449764,"teacher_disagreement_score":0.0022364496,"about_ca_system_score_codex":0.000022651619,"about_ca_system_score_gemma":0.000044175536,"threshold_uncertainty_score":0.7701015},"labels":[],"label_agreement":null},{"id":"W1992950258","doi":"10.1074/jbc.275.18.13727","title":"Export from the Endoplasmic Reticulum Represents the Limiting Step in the Maturation and Cell Surface Expression of the Human δ Opioid Receptor","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":288,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; AstraZeneca (Canada)","funders":"","keywords":"Endoplasmic reticulum; Golgi apparatus; Glycosylation; Receptor; Cell biology; N-linked glycosylation; Secretory pathway; G protein-coupled receptor; Chemistry; Opioid receptor; Glycan; Biochemistry; Biology; Glycoprotein; Opioid","score_opus":0.014154653691806723,"score_gpt":0.23043020479500437,"score_spread":0.21627555110319766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992950258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99799716,0.0009220705,0.000021905993,0.00034559146,0.000058575173,0.00010467238,0.000009123368,0.0000014083021,0.0005394827],"genre_scores_gemma":[0.9986128,0.00059084035,0.00022599238,0.00013719445,0.00029375535,0.0000025329978,0.00001412148,0.000005408236,0.00011731005],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892324,0.00021380708,0.00038818814,0.00016047708,0.00018506157,0.000129218],"domain_scores_gemma":[0.99918896,0.00012378706,0.00033843954,0.00027252996,0.00004932664,0.000026966678],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062640035,0.00011278508,0.00014067053,0.0000028015374,0.0001532123,0.000033027958,0.00048005627,0.00016780116,0.0001933562],"category_scores_gemma":[0.000120245364,0.00004157552,0.00011786864,0.000052696043,0.00012161674,0.0000052346036,0.000089628156,0.0003255165,4.5773172e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006638972,0.000034541314,0.0045538167,0.000005338224,0.000007550975,0.0000012745019,0.00013457747,0.000040765688,0.9943758,0.000001629242,0.0005445674,0.00023370495],"study_design_scores_gemma":[0.0002592747,0.00006648123,0.0040753437,0.00005747901,0.000009768943,0.000024306413,0.0009288493,0.000018183937,0.99214137,0.00010401692,0.0022546393,0.00006028917],"about_ca_topic_score_codex":0.000009661312,"about_ca_topic_score_gemma":8.7830267e-7,"teacher_disagreement_score":0.0022344766,"about_ca_system_score_codex":0.0000067885744,"about_ca_system_score_gemma":0.000021266867,"threshold_uncertainty_score":0.21171148},"labels":[],"label_agreement":null},{"id":"W1992991774","doi":"10.1002/syn.20303","title":"Psychosis pathways converge via D2High dopamine receptors","year":2006,"lang":"en","type":"review","venue":"Synapse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":330,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas College; Douglas Mental Health University Institute; Mount Sinai Hospital; McMaster University; University of Toronto","funders":"National Institute of Mental Health","keywords":"Dopamine receptor D1; Dopamine receptor D2; Dopamine; Internal medicine; Endocrinology; Pharmacology; Dopamine receptor D3; Dopamine receptor; Histamine H3 receptor; Chemistry; Phencyclidine; Receptor; Medicine; Agonist; NMDA receptor","score_opus":0.022933932046066082,"score_gpt":0.2781051202682055,"score_spread":0.2551711882221394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992991774","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000130154,0.99497724,0.0014995232,0.000008857946,0.0015765083,0.0005098935,0.00011524342,0.000042975167,0.0011395894],"genre_scores_gemma":[0.00015930933,0.99264973,0.0005186325,0.00004676365,0.0010686294,0.00015799426,0.002434739,0.0001347276,0.002829455],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976164,0.00017561259,0.00067041744,0.00084131135,0.00021084184,0.0004853879],"domain_scores_gemma":[0.9986596,0.000022926024,0.00037609454,0.00071747426,0.00007377281,0.0001501297],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022994695,0.00062476116,0.0011147594,0.00011474069,0.00010789159,0.00004230758,0.00046490302,0.0008718772,0.00076072547],"category_scores_gemma":[0.00003335655,0.0005240255,0.0007802915,0.0001955822,0.000064229425,0.0000032399507,0.00014408294,0.0002867024,0.00024474345],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025578795,0.00017025512,0.0000042781885,0.0039376705,0.0004725326,0.000030458052,0.000009914778,0.0000019593467,0.008739214,0.00021527156,0.03851243,0.94788045],"study_design_scores_gemma":[0.00017900046,0.00024213578,1.7636638e-7,0.0008419399,0.00023552033,0.000054340348,0.0000039409388,0.0000017814192,0.0040451777,0.000046314195,0.99373317,0.00061648927],"about_ca_topic_score_codex":0.000042075408,"about_ca_topic_score_gemma":0.000012062631,"teacher_disagreement_score":0.95522076,"about_ca_system_score_codex":0.00004396016,"about_ca_system_score_gemma":0.0001071968,"threshold_uncertainty_score":0.9997211},"labels":[],"label_agreement":null},{"id":"W1993077702","doi":"10.1159/000159170","title":"Potentiation of Acetylcholine-lnduced Responses in Freshly Isolated Rabbit Aortic Endothelial Cells","year":2008,"lang":"en","type":"article","venue":"Journal of Vascular Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Acetylcholine; Rabbit (cipher); Long-term potentiation; Lagomorpha; Internal medicine; Medicine; Pharmacology; Chemistry; Endocrinology","score_opus":0.04504034310292156,"score_gpt":0.3280504477519623,"score_spread":0.28301010464904075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993077702","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99618745,0.0011546916,0.0022591876,0.000062149855,0.00013186537,0.00014428579,0.0000056715016,0.000001669878,0.00005304751],"genre_scores_gemma":[0.9963395,0.0022258488,0.00088495016,0.000016750564,0.00021058378,0.0000026186444,0.0000053431677,0.000020320234,0.00029405978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976967,0.0005775154,0.0005607659,0.00017287266,0.0006997711,0.00029236887],"domain_scores_gemma":[0.9987475,0.000054343007,0.00020482572,0.00024526555,0.00064880826,0.0000992145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025259024,0.00010106985,0.0002526749,0.0003726563,0.000079233214,0.000015752004,0.00029038964,0.00016291662,0.00010015958],"category_scores_gemma":[0.00047617266,0.000087349974,0.00024659946,0.00029264067,0.00007567415,0.000012680035,0.00007806535,0.00037535,0.0000065844642],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063025847,0.00013256933,0.00064776436,0.00001712002,0.0000858027,0.000041421037,0.00014086014,0.0003475619,0.99705327,0.000007567699,0.00029788562,0.0005978982],"study_design_scores_gemma":[0.0014492085,0.0007293393,0.0012726597,0.000054016535,0.000011041389,0.00006670076,0.00010648131,0.00027451135,0.9940485,0.000067924215,0.0018333364,0.00008632111],"about_ca_topic_score_codex":0.000045088353,"about_ca_topic_score_gemma":0.000009091105,"teacher_disagreement_score":0.0030048313,"about_ca_system_score_codex":0.00003389627,"about_ca_system_score_gemma":0.00030654148,"threshold_uncertainty_score":0.35620284},"labels":[],"label_agreement":null},{"id":"W1993320226","doi":"10.1016/j.bpj.2013.11.864","title":"Functional Consequences of Cysteine Mutations at the Kainate Receptor Dimer Interface","year":2014,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"","keywords":"Cysteine; Dimer; Chemistry; Kainate receptor; Biophysics; Molecular dynamics; Serine; Hydrogen bond; Amino acid; Receptor; Crystallography; Glutamate receptor; Stereochemistry; Biochemistry; Molecule; Computational chemistry; Biology; AMPA receptor; Organic chemistry; Phosphorylation","score_opus":0.012072100016787069,"score_gpt":0.24460823181286706,"score_spread":0.23253613179608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993320226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97979164,0.00010876695,0.018728599,0.00067502056,0.00038472298,0.000046632482,0.000009472132,0.000003334568,0.00025181496],"genre_scores_gemma":[0.9979227,0.00002474606,0.00037127465,0.00010024112,0.00055577006,0.0000034700686,0.000018714629,0.00000858525,0.0009944509],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993042,0.00010378536,0.00018633746,0.00012420055,0.00015628268,0.0001252468],"domain_scores_gemma":[0.9995379,0.000032275995,0.00013440587,0.00011380744,0.0001199751,0.000061667604],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021024892,0.000086292006,0.00010200603,0.000016251308,0.00017010665,0.000021926688,0.00012711405,0.00005323288,0.000333027],"category_scores_gemma":[0.0000670896,0.00005363435,0.0001198963,0.000050282644,0.00019474291,0.0000039371057,0.000056870427,0.00010539721,0.000036468093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005547524,0.000026537899,0.000033336382,0.0000029914331,0.000042056083,2.4613337e-7,0.000023702993,0.0002664501,0.9964423,0.000658618,0.0016616444,0.000786651],"study_design_scores_gemma":[0.00023368553,0.00033452554,0.00011781704,0.000012422319,0.000015658103,0.000038894217,0.000059555732,0.0001088998,0.98588234,0.00030641,0.012815937,0.00007383843],"about_ca_topic_score_codex":0.0000044936273,"about_ca_topic_score_gemma":0.000001401841,"teacher_disagreement_score":0.018357325,"about_ca_system_score_codex":0.000011531461,"about_ca_system_score_gemma":0.000032070515,"threshold_uncertainty_score":0.36464122},"labels":[],"label_agreement":null},{"id":"W1993460406","doi":"10.1038/ncomms6115","title":"Constitutive phospholipid scramblase activity of a G protein-coupled receptor","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Eye Institute; Weill Cornell Medical College; National Institutes of Health; Brandeis University; University of Toronto; University of Wisconsin-Madison; Velux Stiftung; International Retinal Research Foundation","keywords":"Phospholipid scramblase; Rhodopsin; Flippase; Opsin; Phospholipid; G protein-coupled receptor; Biophysics; Cell biology; Vesicle; Chemistry; Biochemistry; Receptor; Biology; Membrane; Phosphatidylserine; Retinal","score_opus":0.01094410121976561,"score_gpt":0.269610101919921,"score_spread":0.2586660007001554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993460406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9783782,0.0027382553,0.009785146,0.0007317636,0.00024108439,0.00060217554,0.000071790695,0.000032736403,0.0074189],"genre_scores_gemma":[0.9873589,0.00016690831,0.011898937,0.00013459056,0.000068959926,0.000053187352,0.00013459518,0.00001272976,0.00017116849],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931145,0.00012934628,0.00014841622,0.00018179722,0.000101759375,0.00012725263],"domain_scores_gemma":[0.99838865,0.00003899913,0.00013738759,0.0011668173,0.00021195535,0.000056216082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027107116,0.000109631874,0.00014423598,0.000031831565,0.00014751127,0.000012165605,0.0005549612,0.00029104663,0.000056224304],"category_scores_gemma":[0.00033043564,0.00010380597,0.00007935274,0.00010801293,0.00018321992,0.000004801246,0.00023768273,0.0003417482,0.000009883257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004323996,0.000100265504,0.00006389734,0.000007045814,0.00003182989,2.960282e-8,0.000023947017,0.000007031132,0.98430884,0.0131396605,0.00045813835,0.0018161028],"study_design_scores_gemma":[0.00031682313,0.00011919482,0.000090389774,0.000023431696,0.000012611739,0.000001287995,0.000025473635,0.00051291374,0.8926113,0.00015405013,0.10600844,0.00012408696],"about_ca_topic_score_codex":0.00002913722,"about_ca_topic_score_gemma":0.00006087096,"teacher_disagreement_score":0.105550304,"about_ca_system_score_codex":0.000011730733,"about_ca_system_score_gemma":0.00008263672,"threshold_uncertainty_score":0.42330846},"labels":[],"label_agreement":null},{"id":"W1994096904","doi":"10.1139/y06-025","title":"Role of the G<sub>o/i</sub> signaling network in the regulation of neurite outgrowthThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.","year":2006,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health","keywords":"Neurite; Cell biology; Signal transduction; Biology; G protein-coupled receptor; Rap1; Cannabinoid receptor; Receptor; Neuroscience; Biochemistry","score_opus":0.009612854469793083,"score_gpt":0.23852277872017355,"score_spread":0.22890992425038048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994096904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.72729003,0.2706392,0.0000028066427,0.00011702155,0.0007759788,0.00046891067,0.00007987568,5.179869e-7,0.0006256768],"genre_scores_gemma":[0.8396736,0.15941356,0.000029170697,0.000094430754,0.0007146429,0.000007375931,0.000031623622,0.000011575961,0.00002403984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985181,0.0003577286,0.00070210634,0.00016977367,0.00009157016,0.000160721],"domain_scores_gemma":[0.9986771,0.00006009162,0.0009585284,0.00007931314,0.00017715554,0.000047806567],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005272178,0.00015173561,0.0006652114,0.00017257793,0.000035454945,0.000005922587,0.00023698935,0.000306177,0.034015745],"category_scores_gemma":[0.000028280598,0.00011153593,0.00016169931,0.00018421725,0.00020886009,0.0000141298715,0.000027995866,0.00032421306,8.669928e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007374386,0.00002851601,0.00009827653,0.00050727493,0.00018568277,8.1645953e-7,0.00021699654,0.00005951794,0.98585737,0.00004815966,0.0009496847,0.011973982],"study_design_scores_gemma":[0.00054627756,0.00021394638,0.000579226,0.0004975384,0.00019134664,0.000020328027,0.000060662715,0.000025217154,0.9322857,0.0006455159,0.064823076,0.00011116401],"about_ca_topic_score_codex":0.0003489648,"about_ca_topic_score_gemma":0.0016842616,"teacher_disagreement_score":0.112383574,"about_ca_system_score_codex":0.00002262369,"about_ca_system_score_gemma":0.0004774843,"threshold_uncertainty_score":0.96686727},"labels":[],"label_agreement":null},{"id":"W1994190794","doi":"10.1016/j.jaci.2005.12.333","title":"Single and Multiple Doses of Indacaterol, A Novel Once-Daily β2-Agonist, Are Well Tolerated in Patients with Mild Asthma","year":2006,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"ASTER","funders":"","keywords":"Indacaterol; Medicine; B2 receptor; Asthma; Agonist; Anesthesia; Internal medicine; Bronchodilator; Receptor","score_opus":0.012387893482874071,"score_gpt":0.2386062878525457,"score_spread":0.22621839436967162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994190794","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99804586,0.0013804114,0.00026647816,0.00008121838,0.000131704,0.000053692973,0.000005296431,0.0000014393314,0.000033899843],"genre_scores_gemma":[0.9983127,0.0005744261,0.0008786564,0.00007805735,0.000085129024,4.952882e-7,0.000014180379,0.00001072958,0.00004563483],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988525,0.00008109948,0.00065572176,0.00017646512,0.00008032353,0.00015389812],"domain_scores_gemma":[0.9991211,0.000054412078,0.0005087126,0.00009753581,0.00017578663,0.000042432664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020540578,0.00012213562,0.0003497913,0.000054708013,0.00003620853,0.00001344933,0.00009867112,0.00025480217,0.000016615244],"category_scores_gemma":[0.00006447971,0.00009224895,0.000068125075,0.00005112442,0.00017957111,0.000010007064,0.00005923036,0.00020731054,3.1254532e-7],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0059821224,0.001967916,0.47926664,0.000016178241,0.0007725599,0.00001525876,0.00005164313,0.00024608616,0.50780356,0.000060009195,0.00015373246,0.0036643182],"study_design_scores_gemma":[0.011950747,0.008326812,0.88144934,0.00015257894,0.000031771615,0.000036490994,0.00019328995,0.00007672904,0.08932854,0.0000896156,0.008109493,0.0002545873],"about_ca_topic_score_codex":0.0000421929,"about_ca_topic_score_gemma":0.00017217013,"teacher_disagreement_score":0.418475,"about_ca_system_score_codex":0.0000066347197,"about_ca_system_score_gemma":0.000039957275,"threshold_uncertainty_score":0.3761803},"labels":[],"label_agreement":null},{"id":"W1994671614","doi":"10.1016/j.str.2014.03.005","title":"Tracking Allosteric Propagation with HX-MS","year":2014,"lang":"en","type":"letter","venue":"Structure","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Allosteric regulation; Tracking (education); Chemistry; Computational biology; Biophysics; Biochemistry; Biology; Enzyme; Psychology","score_opus":0.007696820527319254,"score_gpt":0.2093259405295236,"score_spread":0.20162912000220434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994671614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60053957,0.0027390614,0.087557085,0.2906278,0.005703593,0.003996613,0.00056723825,0.0003177489,0.007951271],"genre_scores_gemma":[0.56646997,0.000030799445,0.0039861863,0.40510434,0.015648795,0.00003067484,0.005838951,0.00021758239,0.0026727102],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99881357,0.00005906441,0.00015966265,0.0004759879,0.00022089476,0.0002708152],"domain_scores_gemma":[0.9993472,0.0000043661994,0.00016646858,0.0003580116,0.00009088937,0.00003305719],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004912288,0.000299116,0.00022167139,0.000039402905,0.000077640856,0.00006909032,0.00021360393,0.00086616003,0.00025234045],"category_scores_gemma":[0.000011196383,0.00021874944,0.00007967007,0.00005047595,0.000035546724,0.0000026538141,0.000038021677,0.0005648374,0.0000047377885],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030934076,0.0000022292948,0.00002893694,0.0001415625,0.00008979819,0.000028663959,0.000039744846,0.000053477033,0.70349103,0.000011400315,0.29343703,0.0026451573],"study_design_scores_gemma":[0.00021264266,0.00025881483,0.000020119098,0.000057311478,0.00004210551,0.00010197979,0.0000065536988,0.000015927373,0.23433578,0.0001672612,0.764419,0.00036247663],"about_ca_topic_score_codex":0.0000070563524,"about_ca_topic_score_gemma":0.000008993196,"teacher_disagreement_score":0.470982,"about_ca_system_score_codex":0.0000129985965,"about_ca_system_score_gemma":0.000054275904,"threshold_uncertainty_score":0.89203435},"labels":[],"label_agreement":null},{"id":"W1994733893","doi":"10.1097/01.fjc.0000211728.23304.ad","title":"Comparative Study of the Effects of Lacidipine and Enalapril on the Left Ventricular Cardiomyocyte Remodeling in Spontaneously Hypertensive Rats","year":2006,"lang":"en","type":"article","venue":"Journal of Cardiovascular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Lacidipine; Enalapril; Medicine; Contractility; Muscle hypertrophy; Internal medicine; Left ventricular hypertrophy; Spontaneously hypertensive rat; Calcium channel blocker; Lercanidipine; Cardiology; Endocrinology; Angiotensin-converting enzyme; Pharmacology; Blood pressure; Antagonist; Receptor","score_opus":0.008188139540388209,"score_gpt":0.23064341936742486,"score_spread":0.22245527982703664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994733893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851797,0.01349489,0.00031138933,0.00004620773,0.00045994393,0.0004642842,0.0000014506334,9.960539e-7,0.000041113515],"genre_scores_gemma":[0.99909,0.00049946696,0.000046789028,0.00006839067,0.0002685416,0.000004437463,8.1910156e-7,0.000011466658,0.000010043852],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998053,0.0008150452,0.00045878888,0.00017301519,0.00034251634,0.0001576164],"domain_scores_gemma":[0.9990013,0.00011522374,0.00031878796,0.00022377688,0.00030903512,0.00003185456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00088824966,0.00015291593,0.00068442925,0.000082859064,0.00005590219,0.0000060873226,0.00021911667,0.00008457119,0.000005368927],"category_scores_gemma":[0.00006474982,0.00009035115,0.0005222498,0.00011501203,0.00007337761,0.000004715087,0.000084493484,0.00022766765,1.5361915e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029005128,0.0001913645,0.00030652803,0.00003389582,0.0018812928,0.0002767541,0.0002444957,0.06480417,0.9315204,0.000009670482,0.00019517473,0.00024621],"study_design_scores_gemma":[0.002560399,0.0010418865,0.0011133455,0.000058905578,0.00078198634,0.00078967697,0.000465052,0.00029368687,0.99104065,0.000036789865,0.0017126618,0.00010498144],"about_ca_topic_score_codex":0.00004317089,"about_ca_topic_score_gemma":0.000007799316,"teacher_disagreement_score":0.06451048,"about_ca_system_score_codex":0.000023504288,"about_ca_system_score_gemma":0.0000639166,"threshold_uncertainty_score":0.3684413},"labels":[],"label_agreement":null},{"id":"W1994741811","doi":"10.1016/s0924-977x(01)80068-7","title":"Functional genomics of the GPCR family: Identification of novel drug targets for CNS diseases and pain control","year":2001,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AstraZeneca (Canada)","funders":"","keywords":"Identification (biology); Drug; G protein-coupled receptor; Computational biology; Genomics; Biology; Medicine; Bioinformatics; Pharmacology; Genetics; Genome; Gene; Receptor","score_opus":0.012803263923674533,"score_gpt":0.24374379549726743,"score_spread":0.2309405315735929,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994741811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95625645,0.0006407786,0.04149932,0.0002079356,0.00083559105,0.0003533553,0.00010927618,0.000009618704,0.00008769108],"genre_scores_gemma":[0.99796337,0.00024701157,0.00014400219,0.0010193704,0.00028617168,0.000014061579,0.000024336872,0.0000390077,0.00026266076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890924,0.0003028249,0.000315979,0.00026428365,0.00007119385,0.00013648564],"domain_scores_gemma":[0.9993744,0.000059421778,0.00023380092,0.00017685449,0.00010660668,0.000048938422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004381829,0.00010965531,0.00012983047,0.000031016833,0.00006543705,0.000007067877,0.00017568079,0.000028172655,0.00001595391],"category_scores_gemma":[0.000087612585,0.00009120415,0.00010422108,0.00005638524,0.00010445846,0.0000034526245,0.000053418393,0.000055314642,7.6800325e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039221114,0.000120473596,0.0006591434,0.000017996552,0.000048128222,7.377857e-7,0.000022748525,0.0006282836,0.99360466,0.000066594075,0.003152613,0.0012864334],"study_design_scores_gemma":[0.014405841,0.0009934389,0.28193313,0.000025163143,0.0004024336,0.00004263075,0.00017318226,0.007628844,0.53648126,0.00020637401,0.15710217,0.0006055491],"about_ca_topic_score_codex":0.0000012372678,"about_ca_topic_score_gemma":4.2022836e-7,"teacher_disagreement_score":0.4571234,"about_ca_system_score_codex":0.000004222158,"about_ca_system_score_gemma":0.000025082098,"threshold_uncertainty_score":0.37191975},"labels":[],"label_agreement":null},{"id":"W1995084844","doi":"10.1016/j.ddmod.2012.04.001","title":"Models of G-protein-coupled receptor-dependent cardiovascular inflammation","year":2012,"lang":"en","type":"article","venue":"Drug Discovery Today Disease Models","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"","keywords":"Inflammation; G protein-coupled receptor; Neuroscience; Receptor; Biology; Signal transduction; Computational biology; Bioinformatics; Medicine; Immunology; Cell biology; Genetics","score_opus":0.013518372307427558,"score_gpt":0.21334935913955586,"score_spread":0.1998309868321283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995084844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.80157036,0.008204366,0.1889735,0.000031364667,0.00023073182,0.00043582253,0.00010188312,0.00002025355,0.0004317164],"genre_scores_gemma":[0.99706894,0.0004061591,0.00065793755,0.000036498994,0.0005155273,0.00011552599,0.00039288573,0.000055126133,0.00075140246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99805385,0.00013302852,0.00040471356,0.0004279976,0.00053620955,0.00044421526],"domain_scores_gemma":[0.9986723,0.000007785932,0.00014731642,0.00075100356,0.000121011515,0.0003005664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053850457,0.00028277768,0.000330828,0.000069000336,0.000093014896,0.00005056868,0.0002570957,0.00012219019,0.000059107024],"category_scores_gemma":[0.000030717798,0.00026686175,0.00055198657,0.00008721032,0.000048856822,0.00014257363,0.00016989037,0.00009086393,0.000011231398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002716295,0.00015049029,0.000104973566,0.000116768126,0.00035319777,0.0000014583197,0.00024217488,0.3733264,0.61618406,0.008158296,0.0001179379,0.00097261823],"study_design_scores_gemma":[0.001250076,0.00006462591,0.000055631113,0.00012946912,0.00027431364,0.0000018666434,0.0003028202,0.06764757,0.9175569,0.010499977,0.0014058899,0.0008108618],"about_ca_topic_score_codex":0.00006660783,"about_ca_topic_score_gemma":0.0000027642145,"teacher_disagreement_score":0.30567884,"about_ca_system_score_codex":0.00003782835,"about_ca_system_score_gemma":0.0001171628,"threshold_uncertainty_score":0.99997836},"labels":[],"label_agreement":null},{"id":"W1995149758","doi":"10.1016/j.yjmcc.2013.11.017","title":"Angiotensin II induced proteolytic cleavage of myocardial ACE2 is mediated by TACE/ADAM-17: A positive feedback mechanism in the RAS","year":2013,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":333,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; Alberta Innovates; Heart and Stroke Foundation of Canada","keywords":"Angiotensin-converting enzyme 2; Angiotensin II; Internal medicine; Renin–angiotensin system; Endocrinology; Chemistry; Regulator; Cytosol; Reactive oxygen species; Downregulation and upregulation; Enzyme; Endogeny; Biology; Receptor; Medicine; Biochemistry","score_opus":0.005575799692661027,"score_gpt":0.1977754723537206,"score_spread":0.19219967266105956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995149758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9893257,0.0028437357,0.0062728887,0.00068186526,0.00015466473,0.00043825508,0.00001543037,0.0000022668553,0.00026518595],"genre_scores_gemma":[0.998239,0.0002097978,0.00037073312,0.0009122242,0.00016507434,0.000012630942,0.00003156108,0.000025422602,0.000033554865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981132,0.00049373053,0.0005276982,0.0002733781,0.00027620012,0.00031580753],"domain_scores_gemma":[0.99903685,0.00003203093,0.00034130624,0.00025777,0.00022686463,0.00010516502],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007749958,0.00023490706,0.00057034276,0.00010221221,0.000072774,0.000023561612,0.0002744946,0.00038152686,0.000020807693],"category_scores_gemma":[0.00009211956,0.00017211761,0.0003596415,0.00013460328,0.000094346506,0.0000118500575,0.00012073328,0.00032947893,0.0000022360305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009446068,0.000036678,0.000078397665,0.000007837604,0.00028777542,0.000089049216,0.0003183278,0.000013045595,0.99551356,0.00006299383,0.0031373075,0.00036054457],"study_design_scores_gemma":[0.0011783483,0.0014655334,0.00021044836,0.000028294486,0.00010142688,0.0003301176,0.0005706908,0.000036556194,0.9944361,0.0005967612,0.0008522322,0.00019348632],"about_ca_topic_score_codex":0.000042890402,"about_ca_topic_score_gemma":0.0000011819133,"teacher_disagreement_score":0.0089132935,"about_ca_system_score_codex":0.000015974301,"about_ca_system_score_gemma":0.00008571068,"threshold_uncertainty_score":0.7018752},"labels":[],"label_agreement":null},{"id":"W1995156086","doi":"10.1016/j.jaci.2012.12.1354","title":"A Potential Th2 Cell Survival Factor, Amphiregulin Production Is Enhanced Following Neurotransmitter Signaling","year":2013,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Amphiregulin; Neurotransmitter; Neurotransmitter receptor; Cell biology; Chemistry; Neurotransmitter Agents; Epidermal growth factor; Biology; Receptor; Biochemistry","score_opus":0.012765107814238173,"score_gpt":0.26230283299991364,"score_spread":0.24953772518567546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995156086","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98729473,0.0013101113,0.008287878,0.0007324541,0.0022145102,0.00009876215,8.4166646e-7,0.0000050089475,0.00005570107],"genre_scores_gemma":[0.99535936,0.0021106708,0.0009398208,0.0003550715,0.00075480086,0.0000028760603,0.0000037304499,0.000020443262,0.00045322342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983438,0.0002203931,0.00075679563,0.00029135658,0.00014244198,0.00024516106],"domain_scores_gemma":[0.9991537,0.000038475682,0.00036500962,0.00016638503,0.00018310355,0.00009336294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035050567,0.00016799809,0.00034712435,0.00004895369,0.00009813673,0.000039281327,0.00019099125,0.00032506837,0.00029887346],"category_scores_gemma":[0.00008527984,0.00013723176,0.00039268873,0.000046227487,0.00008684795,0.000022962187,0.00006296641,0.00036385487,0.000010466149],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021379378,0.00012292487,0.00024954116,0.0000035361168,0.0006737327,0.0000075518547,0.00007258745,0.00003612563,0.9916963,0.0000067358114,0.0001725902,0.006744593],"study_design_scores_gemma":[0.0019389322,0.0021526867,0.0071395272,0.00003816386,0.00009154777,0.00006351536,0.00030221377,0.00004223431,0.98402375,0.0006005008,0.0033173887,0.0002895426],"about_ca_topic_score_codex":0.00001016084,"about_ca_topic_score_gemma":0.0000030434971,"teacher_disagreement_score":0.00806463,"about_ca_system_score_codex":0.000005546302,"about_ca_system_score_gemma":0.000055969507,"threshold_uncertainty_score":0.5596149},"labels":[],"label_agreement":null},{"id":"W1995183079","doi":"10.1074/jbc.m305952200","title":"Constitutive Activation of the Angiotensin II Type 1 Receptor Alters the Spatial Proximity of Transmembrane 7 to the Ligand-binding Pocket","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Receptor; Ligand (biochemistry); Transmembrane domain; Transmembrane protein; Biophysics; Agonist; Binding site; G protein-coupled receptor; Chemistry; Mutant; Cysteine; Angiotensin II; Stereochemistry; Biochemistry; Biology; Gene; Enzyme","score_opus":0.01932613962643649,"score_gpt":0.23864835260860143,"score_spread":0.21932221298216495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995183079","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997459,0.00018196099,0.001132632,0.0006743687,0.000184937,0.00013590336,0.000012360833,0.0000012531535,0.00021760492],"genre_scores_gemma":[0.9991779,0.000067162924,0.00034412678,0.0001764086,0.00017162546,0.0000014579091,0.0000047452218,0.0000046497044,0.000051954496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999162,0.00010206737,0.00033451573,0.00011972546,0.00015518819,0.00012648357],"domain_scores_gemma":[0.99916434,0.000048188962,0.00035767388,0.00016841768,0.00021753137,0.000043845772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000538308,0.00010737799,0.00018587962,0.0000085748425,0.000121801786,0.0000073342353,0.00028279945,0.00015685085,0.00007865761],"category_scores_gemma":[0.00047762736,0.00004604966,0.00018694426,0.00011957549,0.00016654382,0.00000386681,0.000047805264,0.00019176997,3.1799382e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020720194,0.000045108864,0.0001972592,0.000008515379,0.000058089678,2.792074e-7,0.00009508104,0.00011735374,0.998561,0.000033470395,0.0002873508,0.00038924284],"study_design_scores_gemma":[0.00023666589,0.00029340925,0.00014079556,0.000049045037,0.00001976419,0.000024233439,0.0002349201,0.0000041743674,0.99381375,0.00005660541,0.005063051,0.000063608895],"about_ca_topic_score_codex":0.0000042712177,"about_ca_topic_score_gemma":6.1709164e-7,"teacher_disagreement_score":0.0047757,"about_ca_system_score_codex":0.000014309378,"about_ca_system_score_gemma":0.00010922314,"threshold_uncertainty_score":0.18778506},"labels":[],"label_agreement":null},{"id":"W1995305079","doi":"10.1074/jbc.m507198200","title":"Interactions with PDZ Domain Proteins PIST/GOPC and PDZK1 Regulate Intracellular Sorting of the Somatostatin Receptor Subtype 5","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"","keywords":"PDZ domain; Somatostatin receptor 1; Somatostatin receptor; Cell biology; Golgi apparatus; Receptor; Internalization; Biology; Somatostatin receptor 3; Enzyme-linked receptor; 5-HT5A receptor; Somatostatin receptor 2; Biochemistry","score_opus":0.009184626034548145,"score_gpt":0.22112259110161744,"score_spread":0.2119379650670693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995305079","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971866,0.00058750244,0.0013871643,0.00045460658,0.000047837326,0.00008972269,0.0000071285913,0.0000036006613,0.0002358431],"genre_scores_gemma":[0.9894283,0.00010494506,0.009828099,0.000054414963,0.00032705715,0.0000032673322,0.0000073120195,0.0000106480775,0.0002359767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990302,0.000057928224,0.00044138735,0.00017260655,0.00013496219,0.0001629656],"domain_scores_gemma":[0.9990006,0.000023334154,0.0005914967,0.00016527313,0.00013798827,0.00008127644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003411479,0.0001373551,0.00021209472,0.000012538407,0.00008135641,0.00001869761,0.00019158672,0.00014691171,0.00018058399],"category_scores_gemma":[0.00015159014,0.00007627518,0.00011434364,0.00006714529,0.00014194773,0.000007542706,0.00008026801,0.00024271298,6.7476464e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018010693,0.00006311466,0.0010395935,0.000023583078,0.00005219353,0.0000021871679,0.00004198223,0.000048185724,0.9970248,0.000024202474,0.00010538752,0.0013947053],"study_design_scores_gemma":[0.00039403784,0.00024295147,0.00024957786,0.00008981887,0.000013995847,0.00018885316,0.00024063158,0.000021112819,0.9905602,0.00016661688,0.007724668,0.00010758982],"about_ca_topic_score_codex":0.0000015995198,"about_ca_topic_score_gemma":0.0000016693775,"teacher_disagreement_score":0.008440935,"about_ca_system_score_codex":0.000018462333,"about_ca_system_score_gemma":0.00006222757,"threshold_uncertainty_score":0.31104115},"labels":[],"label_agreement":null},{"id":"W1995371002","doi":"10.1139/y03-071","title":"Mechanism of the negative inotropic effects of α<sub>1</sub>-adrenoceptor agonists on mouse myocardium","year":2003,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"McGill University; Heart and Stroke Foundation of Canada","keywords":"Inotrope; Internal medicine; Beta adrenoceptor; Mechanism (biology); Endocrinology; Adrenergic receptor; Chemistry; Biology; Receptor; Medicine","score_opus":0.004973489894872572,"score_gpt":0.21152514779443535,"score_spread":0.20655165789956278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995371002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99778634,0.00057452486,0.0001274234,0.0000671511,0.0012238543,0.00013924396,0.00001579874,7.846314e-7,0.000064865235],"genre_scores_gemma":[0.9990051,0.0001958202,0.000068980116,0.0005285021,0.00015963557,0.000004009911,0.0000022411689,0.000012646944,0.000023105626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989152,0.00037157346,0.00027150288,0.00015232511,0.00005999876,0.00022941644],"domain_scores_gemma":[0.999167,0.000069363756,0.00032306337,0.00011453499,0.00014715295,0.00017887192],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016110107,0.00014001368,0.00031056962,0.00007978384,0.000098897675,0.0000027756023,0.00018174724,0.00018746301,0.00013030968],"category_scores_gemma":[0.00008790108,0.000105703584,0.00014564583,0.00007022213,0.00024700366,0.000004219965,0.000019151068,0.0002171117,8.6611163e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007628386,0.000024937855,0.00006828013,0.000056215966,0.00019454109,0.0000052019286,0.00011493981,0.00010080764,0.9969822,0.0016369406,0.00057864084,0.0001609692],"study_design_scores_gemma":[0.00088320987,0.00095768645,0.00036321662,0.000018724719,0.000069333655,0.000027822049,0.000034755292,0.000004126913,0.9949461,0.0019475166,0.0006559631,0.00009152827],"about_ca_topic_score_codex":0.000044025463,"about_ca_topic_score_gemma":0.00007043491,"teacher_disagreement_score":0.0020361247,"about_ca_system_score_codex":0.000019251895,"about_ca_system_score_gemma":0.00044026916,"threshold_uncertainty_score":0.4310467},"labels":[],"label_agreement":null},{"id":"W1995535959","doi":"10.1210/en.2003-0597","title":"Identification and Characterization of a Glucagon Receptor from the Goldfish Carassius auratus: Implications for the Evolution of the Ligand Specificity of Glucagon Receptors in Vertebrates","year":2004,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Carassius auratus; Glucagon; Internal medicine; Endocrinology; Receptor; Biology; Glucagon receptor; Ligand (biochemistry); Medicine; Fish <Actinopterygii>; Hormone; Fishery","score_opus":0.01016324842951205,"score_gpt":0.23141000361518074,"score_spread":0.2212467551856687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995535959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914641,0.0008542435,0.0056941584,0.0010075872,0.0003567085,0.000458618,0.0001522798,0.0000032016426,0.000009134233],"genre_scores_gemma":[0.9988631,0.0007090567,0.00009569597,0.00002416034,0.000089618065,0.00006069507,0.000121655845,0.000009511338,0.000026484293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991612,0.00008036708,0.00035506673,0.00020777632,0.000060887745,0.00013469666],"domain_scores_gemma":[0.9991494,0.00007113134,0.0003141088,0.0003337707,0.000118217074,0.00001341745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013767449,0.00009274858,0.00014746236,0.000028882421,0.00008754083,0.000008170391,0.00023447006,0.000095739124,0.0000076726965],"category_scores_gemma":[0.00010688492,0.000057710473,0.00006398944,0.00014777038,0.00017095663,0.00000824347,0.00006266495,0.0000716485,3.469024e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059687154,0.000041108065,0.007007811,0.000010581223,0.00003134904,1.108681e-8,0.00025438104,0.000032083608,0.98796,0.0025194248,0.000031551797,0.0020520454],"study_design_scores_gemma":[0.000380212,0.000086344706,0.09823382,0.000019612524,0.000024842338,0.0000014101075,0.00041810767,0.000035028348,0.8989591,0.0010499649,0.00073940394,0.000052131334],"about_ca_topic_score_codex":0.00045774103,"about_ca_topic_score_gemma":0.0002624292,"teacher_disagreement_score":0.09122601,"about_ca_system_score_codex":0.000034233002,"about_ca_system_score_gemma":0.00006903235,"threshold_uncertainty_score":0.23533648},"labels":[],"label_agreement":null},{"id":"W1995610816","doi":"10.1016/j.bmc.2008.05.066","title":"Selective angiotensin II AT2 receptor agonists: Benzamide structure–activity relationships","year":2008,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Canada Research Chairs; Stiftelsen för Strategisk Forskning","keywords":"Chemistry; Benzamide; Agonist; Receptor; Selectivity; Stereochemistry; Carboxamide; Chemical synthesis; Partial agonist; Substituent; Structure–activity relationship; Functional selectivity; In vitro; Biochemistry","score_opus":0.017494379523683618,"score_gpt":0.2218447784154295,"score_spread":0.20435039889174586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995610816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961957,0.00107623,0.0010490672,0.0003500201,0.00028427134,0.00016396689,0.000051911666,0.000057422712,0.0007714162],"genre_scores_gemma":[0.99505115,0.00016923276,0.001155991,0.00016778921,0.0013507245,0.0000082124125,0.00024232145,0.00005576175,0.0017988357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981378,0.00007914219,0.00031378018,0.00066552043,0.00036475755,0.0004390116],"domain_scores_gemma":[0.9988573,0.000024682708,0.00019388676,0.00047227726,0.00019742709,0.0002543918],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023537877,0.00034349365,0.00031520054,0.00003215112,0.0006760365,0.000014675491,0.00027382214,0.0004985634,0.00074247096],"category_scores_gemma":[0.00041835668,0.00032752965,0.00014540218,0.0002495466,0.00020511846,0.00001010767,0.00014158228,0.00051767175,0.000017075425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011258368,0.000064479194,0.0007936874,0.000022155955,0.00008669503,0.00001048963,0.0001657493,0.000004172649,0.99247676,0.000009378467,0.005925986,0.00032784938],"study_design_scores_gemma":[0.00059033633,0.00019190613,0.0031188808,0.000034662684,0.000037390106,0.00024812738,0.00013709314,0.00002227304,0.98474705,0.00007344895,0.010428675,0.00037016903],"about_ca_topic_score_codex":0.000050521838,"about_ca_topic_score_gemma":0.000009555092,"teacher_disagreement_score":0.0077297366,"about_ca_system_score_codex":0.00011386905,"about_ca_system_score_gemma":0.0003355251,"threshold_uncertainty_score":0.9999177},"labels":[],"label_agreement":null},{"id":"W1995719482","doi":"10.1016/j.cellsig.2015.04.007","title":"Gβ 4 γ 1 as a modulator of M3 muscarinic receptor signalling and novel roles of Gβ 1 subunits in the modulation of cellular signalling","year":2015,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"Signalling; Cell biology; Gq alpha subunit; G protein; HEK 293 cells; G protein-coupled receptor; Signal transduction; Calcium signaling; Hedgehog signaling pathway; Muscarinic acetylcholine receptor; Receptor; Protein subunit; Effector; Biology; Chemistry; Biochemistry; Gene","score_opus":0.026336901804640045,"score_gpt":0.23517500223093177,"score_spread":0.20883810042629172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995719482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84849393,0.0031658665,0.14770758,0.000019872072,0.000110801644,0.0003767406,0.000016981026,0.000008755142,0.00009944692],"genre_scores_gemma":[0.9953173,0.0001523913,0.0040668985,0.000027663997,0.00018940691,0.000017199589,0.00013124327,0.000057526726,0.000040383133],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99724,0.00023182061,0.0010265635,0.00054386933,0.00057881157,0.0003789388],"domain_scores_gemma":[0.9982913,0.00012342006,0.000637652,0.00038580655,0.0004241857,0.0001376311],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019060414,0.000344535,0.00057576224,0.00021017056,0.000074233045,0.000030573217,0.0004747086,0.00034223046,0.00003994296],"category_scores_gemma":[0.00018930047,0.00030733683,0.0002159744,0.00036084504,0.00014127156,0.000026073527,0.00013640716,0.00024696777,0.0000019503645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015735666,0.00015922806,0.00039515432,0.00014019328,0.00008387989,0.000002795924,0.0014505632,0.05093558,0.94527704,0.0007840896,0.000005467122,0.0006086714],"study_design_scores_gemma":[0.0010187863,0.00049443525,0.00003704256,0.0002462459,0.000067131325,0.0000038586963,0.0019363131,0.033358317,0.96143097,0.00097063265,0.00013315868,0.00030309148],"about_ca_topic_score_codex":0.00014520178,"about_ca_topic_score_gemma":0.000018257897,"teacher_disagreement_score":0.14682333,"about_ca_system_score_codex":0.000023461535,"about_ca_system_score_gemma":0.00017344014,"threshold_uncertainty_score":0.9999379},"labels":[],"label_agreement":null},{"id":"W1995781028","doi":"10.1002/pro.285","title":"The importance of valine 114 in ligand binding in β<sub>2</sub>‐adrenergic receptor","year":2009,"lang":"en","type":"article","venue":"Protein Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"U.S. National Library of Medicine; Canadian Institutes of Health Research; Manitoba Medical Service Foundation; Manitoba Health Research Council; University of Pittsburgh; Heart and Stroke Foundation of Canada; National Institutes of Health; National Science Foundation","keywords":"G protein-coupled receptor; Ligand (biochemistry); Chemistry; Receptor; Stereochemistry; Binding site; Amino acid; Agonist; Biochemistry","score_opus":0.008525265996558427,"score_gpt":0.24411492579836624,"score_spread":0.23558965980180782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995781028","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99845904,0.0007362744,0.00018999881,0.00015462724,0.00006836874,0.00023660045,0.0000018834191,0.0000036623833,0.00014956674],"genre_scores_gemma":[0.9988579,0.0001997213,0.00079141394,0.000047641046,0.00004276395,0.000018825245,0.0000031141788,0.000005043229,0.00003353648],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988556,0.000031875417,0.00027577457,0.00031568858,0.00022553588,0.00029553365],"domain_scores_gemma":[0.999535,0.000008976826,0.000113405185,0.00023848371,0.000056682456,0.000047456462],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013190624,0.000093133414,0.00010856419,0.00007937764,0.000098081466,0.000032091502,0.0003747511,0.0000590083,0.0000034736647],"category_scores_gemma":[0.0002208496,0.000069586735,0.000033247954,0.00055115373,0.00015022297,0.000010725492,0.000062945954,0.0000842963,0.0000024504373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025953857,0.000021432877,0.0011264873,0.0000029336643,7.517778e-7,9.944503e-7,0.00003071823,0.00008179515,0.9924948,0.0003242191,0.0000070175624,0.0058828807],"study_design_scores_gemma":[0.00019517643,0.0001714055,0.00093984493,0.000045967943,6.3396175e-7,0.0000013468444,0.000040440864,0.00016331216,0.99753433,0.00059547665,0.00021863701,0.00009342893],"about_ca_topic_score_codex":0.000007859758,"about_ca_topic_score_gemma":0.00005379488,"teacher_disagreement_score":0.0057894518,"about_ca_system_score_codex":0.000024040999,"about_ca_system_score_gemma":0.00012470328,"threshold_uncertainty_score":0.28376648},"labels":[],"label_agreement":null},{"id":"W1996076986","doi":"10.1074/jbc.m109.057174","title":"The Proline-rich N-terminal Domain of G18 Exhibits a Novel G Protein Regulatory Function","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; University of North Carolina at Chapel Hill; Heart and Stroke Foundation of Canada","keywords":"Function (biology); Terminal (telecommunication); Proline; Domain (mathematical analysis); Chemistry; Cell biology; Biochemistry; Biology; Amino acid; Computer science","score_opus":0.010748258386902708,"score_gpt":0.2275665808220806,"score_spread":0.21681832243517787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996076986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974444,0.00035601552,0.0014692398,0.00008627447,0.0001855924,0.000097006545,0.0000050366057,0.0000035961339,0.00035283214],"genre_scores_gemma":[0.9967177,0.000030331914,0.0020512391,0.00003139561,0.0008885622,0.00000691922,0.000007336422,0.000009296088,0.00025721797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998935,0.000030359752,0.0004802814,0.00017128451,0.00019121822,0.0001918435],"domain_scores_gemma":[0.99891055,0.000023466206,0.00050858606,0.00021404511,0.0002485129,0.00009484844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00076166366,0.00013969271,0.00019628945,0.000012461345,0.000092774986,0.000018954315,0.00029129963,0.00033511984,0.00009181979],"category_scores_gemma":[0.00024204848,0.00007932516,0.00018446856,0.00006013671,0.00015967205,0.0000043071664,0.0000737454,0.00036677788,7.769601e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038814693,0.000090503905,0.0002298579,0.000018493856,0.000038835176,0.0000041107396,0.000006651017,0.0000034730242,0.99793285,0.00007749745,0.000121835925,0.0010877333],"study_design_scores_gemma":[0.0004720718,0.00044522673,0.0005303375,0.000024491055,0.000010361166,0.00024306214,0.000068046334,0.0000061898913,0.9884779,0.0005551121,0.009062135,0.00010510558],"about_ca_topic_score_codex":3.989511e-7,"about_ca_topic_score_gemma":5.4775137e-7,"teacher_disagreement_score":0.009455,"about_ca_system_score_codex":0.000008156185,"about_ca_system_score_gemma":0.000095227886,"threshold_uncertainty_score":0.3234786},"labels":[],"label_agreement":null},{"id":"W1996084619","doi":"10.1016/s0165-0173(02)00221-7","title":"Family 1 G protein-coupled receptor function in the CNS Insights from gene knockout mice","year":2003,"lang":"en","type":"review","venue":"Brain Research Reviews","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs","funders":"","keywords":"G protein-coupled receptor; Knockout mouse; Biology; Receptor; Gene knockout; Central nervous system; Gene; Function (biology); Neuroscience; Gene family; Genetics; Cell biology; Genome","score_opus":0.1406976993156428,"score_gpt":0.3859033741374219,"score_spread":0.24520567482177907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996084619","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00050836586,0.99209285,0.00045960737,0.000059445792,0.0002833566,0.005739571,0.00004334772,0.000009424383,0.00080401305],"genre_scores_gemma":[0.000014107745,0.9914491,0.00088113616,0.00038913425,0.00093362597,0.002654423,0.001307482,0.00009933263,0.0022716234],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.98928005,0.0068658045,0.0012007154,0.0011948921,0.00073026854,0.0007282562],"domain_scores_gemma":[0.99766487,0.0002842188,0.00038732478,0.0013168438,0.0001862202,0.00016050936],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005731532,0.0006055956,0.0015379518,0.0002585634,0.0002601997,0.00015776361,0.0011898017,0.00085004116,0.0003627532],"category_scores_gemma":[0.0013272391,0.00037332022,0.0007430268,0.000907474,0.00013485369,0.0000092712335,0.00022939735,0.0013602499,0.00059398846],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035324603,0.0001375667,2.1826537e-7,0.0035558662,0.0001237305,0.000011725361,0.00008382022,3.7505265e-7,0.1725862,0.00020236961,0.035880152,0.78738266],"study_design_scores_gemma":[0.00022973263,0.00026747672,8.641286e-7,0.0043855184,0.000060149992,0.00000459111,0.00006763507,0.000002445862,0.00083038135,0.00014023282,0.9936038,0.0004071725],"about_ca_topic_score_codex":0.00013366224,"about_ca_topic_score_gemma":0.00005634031,"teacher_disagreement_score":0.9577236,"about_ca_system_score_codex":0.00010744527,"about_ca_system_score_gemma":0.00055303087,"threshold_uncertainty_score":0.99987185},"labels":[],"label_agreement":null},{"id":"W1996115435","doi":"10.1074/jbc.m109.012922","title":"Activation Induces Structural Changes in the Liganded Angiotensin II Type 1 Receptor","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Angiotensin II; Mutant; Chemistry; Receptor; Transmembrane domain; Point mutation; Cyanogen bromide; Methionine; Homology modeling; Stereochemistry; Amino acid; Biophysics; Molecular biology; Biochemistry; Peptide sequence; Biology; Enzyme; Gene","score_opus":0.025432302819364226,"score_gpt":0.2645139681977551,"score_spread":0.23908166537839085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996115435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99800605,0.00034670337,0.00002391975,0.0013430236,0.00008550685,0.00004314211,0.0000013830783,0.0000026891798,0.0001475707],"genre_scores_gemma":[0.9980425,0.00017072783,0.0004322124,0.00057065533,0.0007164169,5.4992273e-7,0.000021973608,0.0000033721003,0.000041542924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935097,0.000043710526,0.00021194392,0.0001254324,0.00012360973,0.00014435253],"domain_scores_gemma":[0.99954647,0.00001640817,0.00018993448,0.00010022423,0.000106496926,0.00004048476],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003123562,0.000107550906,0.00015300243,0.000016552369,0.000062350184,0.000019500261,0.0002217432,0.00022930617,0.000091627946],"category_scores_gemma":[0.00016629665,0.000059768656,0.000075258875,0.00010253567,0.000029370916,0.000004518178,0.000025759726,0.00020722591,5.034485e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013646741,0.000028365404,0.00011153948,0.0000017501907,0.000009928986,0.0000028684976,0.0000649853,0.000008233056,0.9968888,0.000008240912,0.0005063128,0.0022324969],"study_design_scores_gemma":[0.00024079515,0.000712447,0.0016979545,0.000020281417,0.0000040090904,0.000052093288,0.000206916,0.000003027214,0.993575,0.0002743975,0.003124281,0.00008879168],"about_ca_topic_score_codex":0.0000010611278,"about_ca_topic_score_gemma":4.229218e-7,"teacher_disagreement_score":0.003313805,"about_ca_system_score_codex":0.000013317086,"about_ca_system_score_gemma":0.000035313213,"threshold_uncertainty_score":0.2437295},"labels":[],"label_agreement":null},{"id":"W1996691586","doi":"10.1016/s0888-7543(03)00173-3","title":"Discovery of a null mutation in a human trace amine receptor gene","year":2003,"lang":"en","type":"article","venue":"Genomics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Biology; Genetics; Gene; G protein-coupled receptor; Null allele; Mutation; Receptor; Allele; Mutant; Population; Signal transduction; Point mutation; Molecular biology","score_opus":0.0089600646827427,"score_gpt":0.22963518554028767,"score_spread":0.22067512085754498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996691586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907032,0.00046146245,0.0082946,0.000008073852,0.00011875252,0.00010590625,0.000014397176,0.0000024030444,0.00029120408],"genre_scores_gemma":[0.99444056,0.00009305948,0.004778554,0.000026974827,0.00005756587,0.00000771272,0.00008314845,0.000015521193,0.0004969064],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994159,0.00003778419,0.00019690458,0.00017547188,0.000049321017,0.0001246482],"domain_scores_gemma":[0.99973094,0.0000040703712,0.0000747043,0.00014523545,0.000023974768,0.000021093394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016294462,0.00008052436,0.00010776235,0.000034483124,0.000023441547,0.000010704112,0.00006950252,0.00008438827,0.000028843313],"category_scores_gemma":[0.000026603655,0.00008437317,0.000050308394,0.000052331863,0.000018439654,0.0000034992702,0.000016108554,0.000041325413,0.000002369105],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019924095,0.000041280713,0.00016167885,0.000008223114,0.000010182852,0.0000013124542,0.00010860287,0.0003718742,0.99836594,0.0005218824,0.000045845234,0.0003432589],"study_design_scores_gemma":[0.00038873713,0.00014124572,0.00010110318,0.000005285415,0.0000046037303,0.000005407962,0.00014014712,0.000027259317,0.995024,0.00028143343,0.003781976,0.00009875071],"about_ca_topic_score_codex":0.000016724256,"about_ca_topic_score_gemma":0.000026486026,"teacher_disagreement_score":0.0037373563,"about_ca_system_score_codex":0.000020601216,"about_ca_system_score_gemma":0.000039846054,"threshold_uncertainty_score":0.3440638},"labels":[],"label_agreement":null},{"id":"W1996774458","doi":"10.1073/pnas.97.7.3684","title":"Detection of β <sub>2</sub> -adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)","year":2000,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":631,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; PerkinElmer Biosignal","funders":"","keywords":"G protein-coupled receptor; Receptor; Förster resonance energy transfer; Agonist; HEK 293 cells; Cell biology; Heterotrimeric G protein; Biophysics; Internalization; Chemistry; G protein; Signal transduction; Bioluminescence; Biochemistry; Biology; Fluorescence","score_opus":0.014529253744786367,"score_gpt":0.2326897283828071,"score_spread":0.21816047463802074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996774458","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9993324,0.00029323922,0.000117616095,0.00002417967,0.000022030032,0.00006238283,0.000005761839,0.000002379992,0.00013996783],"genre_scores_gemma":[0.99896336,0.00040798125,0.0004992977,0.00003837798,0.000060947626,0.0000040343807,3.2297015e-7,0.0000051240595,0.000020548343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989596,0.000012416668,0.00030085162,0.00022653323,0.0003819985,0.00011861388],"domain_scores_gemma":[0.9996808,0.000017994917,0.00014610917,0.0000092604405,0.00012743527,0.000018362105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005115246,0.00008231979,0.00011311338,0.00009038342,0.00008003277,0.000008299758,0.00028172377,0.00011282954,0.000014004629],"category_scores_gemma":[0.00007157877,0.00006666112,0.000059640508,0.0005384677,0.000233029,0.00003224998,0.000030517695,0.000056027267,1.254563e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023300638,0.000023384824,0.00032622457,0.000018931929,0.0000032952248,1.1281017e-9,0.000045133536,0.0009799355,0.9946135,0.0004781786,0.000003458395,0.0034846086],"study_design_scores_gemma":[0.000078331024,0.000069284295,0.001406486,0.00013724386,0.0000040532927,0.0000014729553,0.000036015877,0.0029481356,0.9948062,0.00037409947,0.00006556838,0.000073143914],"about_ca_topic_score_codex":0.00001751818,"about_ca_topic_score_gemma":5.307874e-7,"teacher_disagreement_score":0.0034114646,"about_ca_system_score_codex":0.00001392955,"about_ca_system_score_gemma":0.000026702384,"threshold_uncertainty_score":0.27183616},"labels":[],"label_agreement":null},{"id":"W1996914779","doi":"10.1016/j.cellsig.2011.01.002","title":"Receptor specific crosstalk and modulation of signaling upon heterodimerization between β1-adrenergic receptor and somatostatin receptor-5","year":2011,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Canadian Cancer Society","keywords":"NFAT; Somatostatin receptor; Adenylyl cyclase; Cell biology; Receptor; HEK 293 cells; Chemistry; Signal transduction; Forskolin; Gi alpha subunit; Phosphorylation; Endocrinology; Internal medicine; Biology; G protein; Biochemistry; Transcription factor","score_opus":0.023304210551486283,"score_gpt":0.21224610901032637,"score_spread":0.18894189845884007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996914779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90973365,0.002086479,0.08754681,0.000008272107,0.00020776516,0.00026587083,0.000036442183,0.000028528104,0.00008618179],"genre_scores_gemma":[0.978598,0.0006506185,0.019623185,0.00001553385,0.0003370716,0.000013254359,0.0006132412,0.00007179379,0.000077279765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979761,0.00016233392,0.0006176982,0.0006582428,0.00023954241,0.00034607534],"domain_scores_gemma":[0.9990234,0.000036680467,0.00036195738,0.00025620722,0.00015329526,0.00016848832],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005234801,0.00032481266,0.00037016373,0.00012314317,0.00020851799,0.000064169,0.00015864719,0.0003006619,0.00035261916],"category_scores_gemma":[0.000036986567,0.0003399554,0.000102834696,0.00015498756,0.00011430675,0.000030174988,0.00010622207,0.00014417159,0.000008504039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000964262,0.000033829187,0.0022672305,0.00006882417,0.000064992135,7.6220823e-7,0.0007402033,0.0003053283,0.9925441,0.00019917116,0.000021205467,0.0036578972],"study_design_scores_gemma":[0.0005317812,0.00033169435,0.00019825304,0.00010517736,0.000029944418,0.0000019768609,0.0002938023,0.0006849198,0.9961105,0.00024997603,0.0010775393,0.00038441148],"about_ca_topic_score_codex":0.000025958152,"about_ca_topic_score_gemma":0.0000012964969,"teacher_disagreement_score":0.06886437,"about_ca_system_score_codex":0.000016842785,"about_ca_system_score_gemma":0.0000326767,"threshold_uncertainty_score":0.9999052},"labels":[],"label_agreement":null},{"id":"W1997120391","doi":"10.1111/gbb.12183","title":"<scp>NMDA</scp> receptor‐deficient mice display sexual dimorphism in the onset and severity of behavioural abnormalities","year":2014,"lang":"en","type":"article","venue":"Genes Brain & Behavior","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Stereotypy; Sexual dimorphism; NMDA receptor; Juvenile; Gene knockdown; Schizophrenia (object-oriented programming); Psychology; Neuroscience; Receptor; Internal medicine; Endocrinology; Biology; Medicine; Psychiatry; Genetics; Amphetamine; Gene","score_opus":0.01851829771188844,"score_gpt":0.2417534715393862,"score_spread":0.22323517382749775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997120391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99831504,0.0006645048,0.00026971422,0.00007687135,0.0002352509,0.00027894604,0.00011237686,0.000008952651,0.000038336308],"genre_scores_gemma":[0.99815565,0.000063560896,0.0005982637,0.00025486006,0.00011123858,0.00008138201,0.00019895699,0.000023080112,0.00051303377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851906,0.0002474223,0.00031401796,0.00036624388,0.00022350384,0.0003297287],"domain_scores_gemma":[0.99930096,0.000111417,0.00011936352,0.0003421611,0.00005555975,0.00007056624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007716121,0.00021351312,0.00021658838,0.00005261024,0.00011583288,0.00004140815,0.00028050484,0.0001812922,0.00002487426],"category_scores_gemma":[0.000110479305,0.00017017705,0.000076585275,0.0000896149,0.00014249867,0.000008667116,0.00013466908,0.00013386467,0.0000034636755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013688257,0.00015287098,0.082088895,0.000020075031,0.000008951284,0.0000025263093,0.0013099589,0.000010991586,0.9103752,0.000102889964,0.0011990278,0.0047149733],"study_design_scores_gemma":[0.00095529575,0.0008123888,0.20308906,0.00003112087,0.000083353276,0.00009023377,0.0060828486,0.0000647517,0.764851,0.000029104516,0.023619058,0.00029179227],"about_ca_topic_score_codex":0.0003129427,"about_ca_topic_score_gemma":0.00018626744,"teacher_disagreement_score":0.14552416,"about_ca_system_score_codex":0.000011239001,"about_ca_system_score_gemma":0.000034931716,"threshold_uncertainty_score":0.6939619},"labels":[],"label_agreement":null},{"id":"W1997193622","doi":"10.1159/000137342","title":"Effects of Paired Analogs of Angiotensin II and Angiotensin III on Rat Smooth Muscle","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Angiotensin II; Chemistry; Renin–angiotensin system; Endocrinology; Angiotensin III; Internal medicine; Angiotensin receptor; Angiotensin II receptor type 1; Sarcosine; Angiotensin-converting enzyme; Receptor; Amino acid; Biochemistry; Biology; Glycine; Blood pressure; Medicine","score_opus":0.010622761874038805,"score_gpt":0.24121630383053672,"score_spread":0.23059354195649792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997193622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973904,0.0014780286,0.0003316143,0.00017798503,0.0003385387,0.00019564734,0.00000559785,0.000008154552,0.00007401477],"genre_scores_gemma":[0.9980536,0.00045994273,0.0006495232,0.0005040268,0.00014501017,0.0000062126182,0.00001493617,0.000016521319,0.00015021584],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915594,0.00009656523,0.00020723097,0.00025851774,0.000083943574,0.00019777581],"domain_scores_gemma":[0.9995672,0.00004253777,0.00012027981,0.000115466806,0.00008420837,0.00007028523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011260594,0.00013683789,0.00027248636,0.00006788562,0.000081233055,0.0000013095223,0.000086091895,0.00014232464,0.000053250365],"category_scores_gemma":[0.000026231583,0.0001271555,0.000098507735,0.000078006175,0.00015377258,0.0000025313232,0.00008720585,0.00007026863,9.570822e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016442896,0.00012770086,0.00014651091,0.000021647658,0.000068655005,0.000016471002,0.00011115489,0.000038325485,0.99206877,0.00003598098,0.0056248764,0.001575457],"study_design_scores_gemma":[0.0015183801,0.0010063429,0.0026049488,0.000011244654,0.000053903637,0.000010633044,0.000008890267,0.00009428001,0.9885244,0.00003063051,0.0060174707,0.000118876385],"about_ca_topic_score_codex":0.000029732682,"about_ca_topic_score_gemma":0.0000021166527,"teacher_disagreement_score":0.0035443918,"about_ca_system_score_codex":0.0000058892338,"about_ca_system_score_gemma":0.000037249087,"threshold_uncertainty_score":0.518525},"labels":[],"label_agreement":null},{"id":"W1997319343","doi":"10.1111/j.1471-4159.2004.02536.x","title":"Oligomeric potential of the M<sub>2</sub> muscarinic cholinergic receptor","year":2004,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Heart and Stroke Foundation of Canada","keywords":"Immunoprecipitation; Muscarinic acetylcholine receptor; Receptor; Hemagglutinin (influenza); Chemistry; Population; Dimer; Epitope; Molecular biology; Monomer; Biophysics; Biology; Antibody; Biochemistry; Immunology; Medicine","score_opus":0.004619735928733187,"score_gpt":0.20048771559985948,"score_spread":0.1958679796711263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997319343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979126,0.0004382897,0.0006590172,0.00015149622,0.0006603471,0.000045968973,0.000005534225,0.000002958034,0.0001238108],"genre_scores_gemma":[0.9982936,0.0004176532,0.00029789965,0.00014899754,0.00076414214,0.0000012329305,0.000004382945,0.00002294525,0.000049184997],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886143,0.00003287576,0.00046795898,0.00017036406,0.00028379966,0.00018359128],"domain_scores_gemma":[0.998875,0.0000063949883,0.0005377019,0.00028330932,0.00020033664,0.000097237076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015319748,0.00015188585,0.00020900954,0.000028340299,0.000057600424,0.000015416892,0.00043522633,0.00014332362,0.000023200133],"category_scores_gemma":[0.00011228981,0.00011240705,0.0003737396,0.00012870721,0.000070743175,0.0000058342207,0.00011008159,0.00025849434,0.000001901606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006579666,0.000073421266,0.00004233342,0.000025959858,0.000041472067,0.000007047433,0.000015014133,0.0023321407,0.996715,0.000005890682,0.00025005583,0.00042585528],"study_design_scores_gemma":[0.0007288026,0.00018218052,0.0006162239,0.000049064096,0.000036673377,0.0003026546,0.000045087865,0.0000054037273,0.997082,0.00009734927,0.00074504816,0.00010953311],"about_ca_topic_score_codex":0.0000011933267,"about_ca_topic_score_gemma":2.4378542e-7,"teacher_disagreement_score":0.0023267372,"about_ca_system_score_codex":0.000018186296,"about_ca_system_score_gemma":0.00018247608,"threshold_uncertainty_score":0.45838264},"labels":[],"label_agreement":null},{"id":"W1997565994","doi":"10.1016/j.bbr.2012.10.005","title":"Role of cholinergic-muscarinic receptors in visual discrimination performance of rats: Importance of stimulus load","year":2012,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Stimulus (psychology); Psychology; Neuroscience; Muscarinic acetylcholine receptor; Cholinergic; Cognition; Sensory cue; Visual perception; Water maze; Perception; Cognitive psychology; Receptor; Medicine; Internal medicine","score_opus":0.045986765179492683,"score_gpt":0.3580142835948032,"score_spread":0.3120275184153105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997565994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998524,0.00095225853,0.000013980398,0.000027925473,0.00006782456,0.00020365477,0.000010236517,0.0000022531535,0.00019785856],"genre_scores_gemma":[0.99922115,0.00012245703,0.0002647055,0.000005508545,0.00005719594,0.000019782166,0.000059910424,0.000015404014,0.0002338919],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983976,0.00016255319,0.00042303215,0.00018954235,0.00047951538,0.00034779712],"domain_scores_gemma":[0.99919736,0.000044217715,0.0001451377,0.0002218449,0.00031820423,0.00007320448],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017037586,0.000100958685,0.0001984207,0.00013004275,0.00003072636,0.00000448084,0.00021260082,0.00014058777,0.00011662351],"category_scores_gemma":[0.00022765482,0.000092050395,0.00007479969,0.00026072396,0.00012828487,0.000017497952,0.00013764061,0.00017005393,0.0000013573277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011967943,0.00015970407,0.29009166,0.000037124883,0.0000055198966,1.466005e-7,0.00021196072,0.000033374996,0.70516825,0.00006667745,0.000053141277,0.0040527293],"study_design_scores_gemma":[0.00035350327,0.0005434915,0.10952739,0.00004910365,0.000004662076,0.0000012137707,0.000586174,0.00026414357,0.8884715,0.000014375041,0.00009719244,0.00008727471],"about_ca_topic_score_codex":0.00023258546,"about_ca_topic_score_gemma":0.000064903885,"teacher_disagreement_score":0.1833032,"about_ca_system_score_codex":0.000039173785,"about_ca_system_score_gemma":0.000114377784,"threshold_uncertainty_score":0.37537062},"labels":[],"label_agreement":null},{"id":"W1997574561","doi":"10.1038/nmeth722","title":"Real-time monitoring of ubiquitination in living cells by BRET","year":2004,"lang":"en","type":"article","venue":"Nature Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":144,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"European Molecular Biology Organization","keywords":"Ubiquitin; Cell biology; Proteasome; Biology; G protein-coupled receptor; Förster resonance energy transfer; Regulator; Ubiquitin ligase; HEK 293 cells; F-box protein; Receptor; Chemistry; Signal transduction; Biochemistry; Fluorescence; Gene","score_opus":0.006604563167454333,"score_gpt":0.32166343963880467,"score_spread":0.31505887647135034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997574561","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9515305,0.0011585196,0.045939814,0.00002674555,0.00034111197,0.000098241326,0.000006270625,0.000010131723,0.0008886411],"genre_scores_gemma":[0.70174915,0.00020329915,0.29764628,0.000018465385,0.00014470365,0.0000047046547,0.00001306425,0.000015682232,0.00020464632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992212,0.00015120511,0.00017519167,0.00020624948,0.00010106404,0.00014505595],"domain_scores_gemma":[0.999639,0.000043672302,0.00008151629,0.0001471745,0.00005649805,0.000032151605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008573527,0.00009498636,0.00013675787,0.00004776045,0.000022705943,0.000008975699,0.000114213806,0.00036220168,0.000026806518],"category_scores_gemma":[0.00016079872,0.00009384068,0.000054622556,0.00010877646,0.0000135188475,0.0000037099028,0.00004463485,0.00018870854,0.000001026267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008533061,0.00002472704,0.00012566049,0.000013445264,0.0000076084307,5.412919e-7,0.00008602042,0.00014604343,0.9952153,0.00012171995,0.00005358664,0.0041968315],"study_design_scores_gemma":[0.00016780164,0.00007774855,0.00026354069,0.00006110555,0.0000049039736,0.0000013416196,0.000060538598,0.00002450889,0.9981737,0.00039827457,0.0006706091,0.00009591274],"about_ca_topic_score_codex":0.00002847167,"about_ca_topic_score_gemma":7.926414e-7,"teacher_disagreement_score":0.25170648,"about_ca_system_score_codex":0.000024398725,"about_ca_system_score_gemma":0.000030673924,"threshold_uncertainty_score":0.3826712},"labels":[],"label_agreement":null},{"id":"W1997663619","doi":"10.1158/1535-7163.targ-13-a236","title":"Abstract A236: The orphan G-protein coupled receptor GPR161 is an oncogene in triple negative breast cancer.","year":2013,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Triple-negative breast cancer; Cancer research; Cancer; Biology; Breast cancer; mTORC1; Carcinogenesis; Gene knockdown; PI3K/AKT/mTOR pathway; Cell growth; Oncogene; Signal transduction; Cell biology; Cell culture; Genetics; Cell cycle","score_opus":0.019466022167806518,"score_gpt":0.27534674363905204,"score_spread":0.2558807214712455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997663619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916983,0.0037111216,0.0011352942,0.0019731289,0.0003050995,0.0009349972,0.00012350999,0.000020853613,0.000097650605],"genre_scores_gemma":[0.9929117,0.0012374757,0.00052121293,0.0039056907,0.00030814772,0.0006132414,0.00005405539,0.00008500572,0.00036349354],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813914,0.00013346305,0.0003626043,0.0005588215,0.00030139976,0.00050458673],"domain_scores_gemma":[0.99888945,0.000010171023,0.0001818409,0.0005673179,0.00021815652,0.00013305507],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023463865,0.00034371568,0.00026867774,0.000052384057,0.00015046216,0.000108583205,0.00048578138,0.00025718933,0.002250631],"category_scores_gemma":[0.000007158223,0.00026731176,0.00015062571,0.00024168486,0.000105730585,0.000018337125,0.000077378616,0.00025648385,0.000028195587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011931191,0.0000884843,0.00021404357,0.000012744997,0.00016566574,0.0000029243843,0.00032560286,0.00029444232,0.97810626,0.000039098486,0.00017940458,0.020452028],"study_design_scores_gemma":[0.0011304852,0.00016586565,0.0013928652,0.000054811226,0.00003677218,0.000004026687,0.00035150524,0.0013031305,0.9893768,0.00038369998,0.0053732563,0.00042681408],"about_ca_topic_score_codex":0.003923396,"about_ca_topic_score_gemma":0.000605913,"teacher_disagreement_score":0.020025214,"about_ca_system_score_codex":0.00010353493,"about_ca_system_score_gemma":0.00024825445,"threshold_uncertainty_score":0.9999779},"labels":[],"label_agreement":null},{"id":"W1997772449","doi":"10.1016/j.cellsig.2011.08.008","title":"The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner","year":2011,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Homologous desensitization; Receptor; Sensitization; Desensitization (medicine); Cell biology; Adenylyl cyclase; Forskolin; Biology; Chemistry; Pharmacology; Biochemistry; Neuroscience","score_opus":0.015359871388300719,"score_gpt":0.19085538532813312,"score_spread":0.1754955139398324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997772449","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9803551,0.0032142808,0.01573666,0.000041081028,0.00020379142,0.00027582975,0.0000037596183,0.000011128031,0.00015839412],"genre_scores_gemma":[0.9961452,0.002783308,0.0006730566,0.000019191646,0.00009153141,0.000009601475,0.00013092144,0.000029164381,0.00011805814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872833,0.00013974596,0.00044037995,0.0003093987,0.00014564737,0.00023650724],"domain_scores_gemma":[0.99931556,0.000056566547,0.00021573482,0.0001847865,0.00015511033,0.00007227143],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000626479,0.00020263501,0.00019834696,0.00008533691,0.0001659011,0.000042618074,0.0001038508,0.00018491538,0.00003280577],"category_scores_gemma":[0.000045711302,0.00015983815,0.00004638028,0.00012878956,0.000087154665,0.000021866288,0.00006683467,0.00012788823,0.000003221345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089264424,0.00002237006,0.0005355337,0.000028228693,0.000028707527,0.0000023415491,0.0009305159,0.00020700108,0.9953731,0.00086531945,0.000019994444,0.0018976772],"study_design_scores_gemma":[0.00039381388,0.00015317611,0.00007078437,0.000057706584,0.0000127590765,0.0000075165203,0.001247197,0.0041410923,0.9929207,0.0004486331,0.00034618346,0.00020042976],"about_ca_topic_score_codex":0.000030429408,"about_ca_topic_score_gemma":0.000022053038,"teacher_disagreement_score":0.015790092,"about_ca_system_score_codex":0.000014568172,"about_ca_system_score_gemma":0.000027209035,"threshold_uncertainty_score":0.65180105},"labels":[],"label_agreement":null},{"id":"W1997968915","doi":"10.1016/j.regpep.2009.08.011","title":"The role of G-proteins in the dimerisation of human somatostatin receptor types 2 and 5","year":2009,"lang":"en","type":"article","venue":"Regulatory Peptides","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; McGill University","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"G protein-coupled receptor; Somatostatin receptor; Receptor; Somatostatin receptor 1; Somatostatin; Somatostatin receptor 2; Somatostatin receptor 3; G protein; Agonist; Rhodopsin-like receptors; Cell biology; 5-HT5A receptor; Pertussis toxin; Biology; Chemistry; Biochemistry; Endocrinology; Metabotropic receptor","score_opus":0.0057730935837157216,"score_gpt":0.22806686984825594,"score_spread":0.22229377626454022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997968915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976843,0.0018583746,0.00001909446,0.00005693615,0.000011887022,0.000112982016,0.0000023707657,0.0000019763309,0.0002520793],"genre_scores_gemma":[0.9995586,0.00008366125,0.00023506935,0.000023548797,0.00003819733,0.0000046932805,0.000008821542,0.0000045203615,0.00004283917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951977,0.000056579935,0.0001618052,0.00009434344,0.000089516674,0.000077969424],"domain_scores_gemma":[0.99968463,0.000015144477,0.00009401552,0.00016634291,0.000027638345,0.000012235188],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028697317,0.000058877147,0.00007770795,0.000015949086,0.00006790619,0.0000088868965,0.00009934921,0.000047799535,0.000007773069],"category_scores_gemma":[0.000025225761,0.000036426678,0.00003204528,0.000037994825,0.000071167844,0.000002938592,0.000014006401,0.000033135846,3.422065e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014359791,0.00001616507,0.0011170434,0.0000049185696,0.000006531211,4.3503963e-8,0.00030301572,0.000010521539,0.9883399,0.0036165435,0.000055387016,0.00651557],"study_design_scores_gemma":[0.00011024448,0.00021983944,0.016459703,0.000019184017,0.0000043386535,9.060374e-7,0.001036567,0.000019303981,0.9774104,0.0033265043,0.0013437804,0.000049257553],"about_ca_topic_score_codex":0.000015228286,"about_ca_topic_score_gemma":0.000016102722,"teacher_disagreement_score":0.015342661,"about_ca_system_score_codex":0.0000026992925,"about_ca_system_score_gemma":0.000013695154,"threshold_uncertainty_score":0.14854367},"labels":[],"label_agreement":null},{"id":"W1998670974","doi":"10.1016/s0014-2999(00)00562-8","title":"The dopamine D4 receptor: one decade of research","year":2000,"lang":"en","type":"review","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":422,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Dopamine; Dopaminergic; Dopamine receptor; D1-like receptor; D2-like receptor; Dopamine receptor D3; Dopamine receptor D2; Neuroscience; Biology; Dopamine receptor D1; Receptor; Genetics","score_opus":0.08086551439314325,"score_gpt":0.3977536987459716,"score_spread":0.31688818435282834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998670974","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004142116,0.9955395,0.000090332374,0.0000945779,0.0011092612,0.000247028,0.000017217102,0.0000029821767,0.0024849041],"genre_scores_gemma":[0.00034691216,0.9947901,0.00039134038,0.00004619007,0.00287871,0.00000424326,0.000022155093,0.00008307509,0.0014372957],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9935192,0.004156126,0.0012527617,0.00027110064,0.00037660782,0.00042421988],"domain_scores_gemma":[0.99797153,0.00023477219,0.00097170554,0.00026113537,0.00041825406,0.00014257616],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.005481797,0.00026330128,0.00086294493,0.00021305656,0.000175154,0.00002826214,0.0012024768,0.00014927288,0.000924601],"category_scores_gemma":[0.00014313147,0.00017408925,0.00055570906,0.0002375508,0.00028565107,0.0000037664386,0.00022777822,0.001036304,0.000076687444],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016550891,0.00009907536,1.5854698e-7,0.0006272116,0.0006045004,0.00006442979,0.000020981335,0.000005947032,0.09795107,0.00002393686,0.030587176,0.86985],"study_design_scores_gemma":[0.00043207916,0.0010665217,2.2317187e-7,0.00096375385,0.00028045187,0.00019653121,0.000017223972,4.0853138e-7,0.027707983,0.000007516478,0.9691791,0.00014819935],"about_ca_topic_score_codex":7.1038636e-7,"about_ca_topic_score_gemma":3.2516857e-7,"teacher_disagreement_score":0.93859196,"about_ca_system_score_codex":0.000035608162,"about_ca_system_score_gemma":0.00036542237,"threshold_uncertainty_score":0.9999887},"labels":[],"label_agreement":null},{"id":"W1998852252","doi":"10.1016/j.bpj.2012.11.2259","title":"Water Matters: Role of Water in the Binding Selectivity of β-Blockers to Human β-Adrenergic Receptors","year":2013,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Receptor; Allosteric regulation; Homology modeling; Chemistry; Molecular dynamics; Binding site; Druggability; Adrenergic receptor; Molecular model; Biophysics; Computational biology; Stereochemistry; Computational chemistry; Biochemistry; Biology; Enzyme","score_opus":0.007112640384312244,"score_gpt":0.22522878541454994,"score_spread":0.21811614503023768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998852252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.999243,0.0000073830147,0.000119532284,0.00039474337,0.000080476995,0.0001036271,0.0000014287529,0.0000016807877,0.000048096113],"genre_scores_gemma":[0.99932647,0.0000044752087,0.0002325039,0.00014049273,0.00021858358,0.0000083504765,0.000009600375,0.000011888832,0.00004765343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990725,0.00010425477,0.0002500452,0.00014434331,0.00017193385,0.00025690874],"domain_scores_gemma":[0.9996723,0.000006214176,0.00005635099,0.00013387384,0.00006854427,0.000062720035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025379276,0.00010930828,0.0001642854,0.000064355365,0.000067366986,0.00003004079,0.0002338473,0.00007131634,0.00021828663],"category_scores_gemma":[0.000005439922,0.00005558414,0.00012154249,0.00006584592,0.00003745473,0.000008185198,0.00006587747,0.00012968802,0.000019627874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001937531,0.000082964914,0.00031593608,0.0000054544757,0.00002333171,6.7187506e-7,0.00042267668,0.00004386789,0.9982379,0.00002682801,0.0004171808,0.00040381402],"study_design_scores_gemma":[0.00018265568,0.0003259425,0.00027590242,0.000016855372,0.000007613086,0.000009574302,0.00033171667,0.000015816817,0.9977622,0.0002145128,0.00076520146,0.00009199582],"about_ca_topic_score_codex":0.00007531602,"about_ca_topic_score_gemma":0.000003401018,"teacher_disagreement_score":0.00059978256,"about_ca_system_score_codex":0.000011431928,"about_ca_system_score_gemma":0.000008779805,"threshold_uncertainty_score":0.23900855},"labels":[],"label_agreement":null},{"id":"W1998949716","doi":"10.1124/mol.105.020883","title":"Identification of Various Allosteric Interaction Sites on M1 Muscarinic Receptor Using 125I-Met35-Oxidized Muscarinic Toxin 7","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Allosteric regulation; Cooperativity; Chemistry; Stereochemistry; Ternary complex; Muscarinic acetylcholine receptor; Cooperative binding; Binding site; Dissociation constant; Ternary operation; Receptor; Biochemistry; Enzyme","score_opus":0.014191989057299558,"score_gpt":0.2945049556917786,"score_spread":0.280312966634479,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998949716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877,0.0003553388,0.010084574,0.00007221244,0.0011881599,0.00037336804,0.000017638184,0.000026801048,0.00018190949],"genre_scores_gemma":[0.99752694,0.000054410502,0.0012248704,0.0003616379,0.0003036582,0.00004118578,0.00022512952,0.00005309434,0.00020906677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980114,0.0002723498,0.00062191504,0.0005678072,0.00019430512,0.00033220847],"domain_scores_gemma":[0.9990237,0.000033647764,0.00041077065,0.00031776962,0.00014509623,0.000069028174],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003442696,0.0002618593,0.0003045474,0.00017390793,0.00007872497,0.000029028222,0.00025371285,0.00025845267,0.0004914374],"category_scores_gemma":[0.00004563557,0.0002841409,0.0002300576,0.00019716047,0.000059437603,0.000010906056,0.00012470926,0.00017309458,0.000030066361],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025449696,0.00023053799,0.000063557396,0.00002782392,0.00013116747,0.000009293671,0.000023093276,0.003919115,0.99408525,0.000116265604,0.0007035043,0.00043586802],"study_design_scores_gemma":[0.0011145708,0.0003881957,0.000112692374,0.000013131351,0.000119612625,0.000019781446,0.000023410965,0.0026501995,0.9915467,0.00007802216,0.0036734086,0.00026029683],"about_ca_topic_score_codex":0.000085027576,"about_ca_topic_score_gemma":0.000007513774,"teacher_disagreement_score":0.009826948,"about_ca_system_score_codex":0.00006620962,"about_ca_system_score_gemma":0.000067075496,"threshold_uncertainty_score":0.9999611},"labels":[],"label_agreement":null},{"id":"W1999011552","doi":"10.1016/j.neuron.2009.07.010","title":"Linking Genetically Defined Neurons to Behavior through a Broadly Applicable Silencing Allele","year":2009,"lang":"en","type":"article","venue":"Neuron","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Helen Hay Whitney Foundation; National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institutes of Health; Foundation Fighting Blindness","keywords":"Neuroscience; Serotonergic; Biology; Neurotransmission; Excitatory postsynaptic potential; Neuron; Postsynaptic potential; Gene silencing; Inhibitory postsynaptic potential; Genetics; Gene; Serotonin","score_opus":0.013843534974123944,"score_gpt":0.255506015205285,"score_spread":0.24166248023116105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999011552","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97592014,0.00016628747,0.021611257,0.00028976853,0.0001407125,0.00035337912,0.0000047315652,0.000044461784,0.0014692717],"genre_scores_gemma":[0.98377377,0.00006602876,0.011870682,0.0035877535,0.00031426066,0.00004379424,0.00003731617,0.000035691355,0.0002707033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99862576,0.000039920025,0.00022439742,0.00053420744,0.0001764627,0.00039925106],"domain_scores_gemma":[0.99937916,0.000008852697,0.00004824226,0.00038162485,0.000049046455,0.00013307144],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008100144,0.00019551248,0.00015987044,0.000028457387,0.00012841538,0.000054924625,0.00024891229,0.00013339453,0.000069303846],"category_scores_gemma":[0.000036333873,0.00020034738,0.00009883097,0.000107392465,0.00001409348,0.000004856397,0.00009067146,0.00013604929,0.00004223207],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025873844,0.00006620346,0.00014401817,0.0000035974415,0.0000034004215,0.000009698393,0.000043632914,0.00047432297,0.98604286,0.00023856624,0.0005774992,0.0123703135],"study_design_scores_gemma":[0.00036991673,0.0014373972,0.0026995465,0.000012976322,0.000029678764,0.000028470758,0.000026464691,0.00015260997,0.9423783,0.00022844653,0.05230564,0.0003305978],"about_ca_topic_score_codex":0.000016714912,"about_ca_topic_score_gemma":0.0000075053126,"teacher_disagreement_score":0.05172814,"about_ca_system_score_codex":0.000010465717,"about_ca_system_score_gemma":0.000037361267,"threshold_uncertainty_score":0.8169929},"labels":[],"label_agreement":null},{"id":"W1999097523","doi":"10.1016/j.yexmp.2015.05.002","title":"Betacellulin transgenic mice develop urothelial hyperplasia and show sex-dependent reduction in urinary major urinary protein content","year":2015,"lang":"en","type":"article","venue":"Experimental and Molecular Pathology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Cancer Research Society","keywords":"Urothelium; Epidermal growth factor; Hyperplasia; Stromal cell; Biology; Cell biology; ErbB; Urothelial Cell; Receptor tyrosine kinase; Epidermal growth factor receptor; Genetically modified mouse; Receptor; Transgene; Urinary bladder; Cancer research; Signal transduction; Endocrinology; Internal medicine; Urinary system; Medicine; Biochemistry","score_opus":0.021193147924844204,"score_gpt":0.24442596212393625,"score_spread":0.22323281419909205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999097523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888795,0.008862032,0.0013306027,0.00009904138,0.000172899,0.00047234006,0.000010824765,0.000013167573,0.0001595962],"genre_scores_gemma":[0.99621576,0.000069272115,0.002794391,0.000117710224,0.0000834511,0.00013132305,0.000052235184,0.00003065524,0.00050517346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864906,0.00017419216,0.0002429714,0.00053835707,0.00011934321,0.00027609116],"domain_scores_gemma":[0.9996098,0.000002209608,0.000053261978,0.0001484478,0.000034046898,0.0001522286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023006537,0.0002257495,0.00021592627,0.000065746426,0.000060228285,0.000020012612,0.00009233599,0.00020962105,0.000014738047],"category_scores_gemma":[0.000012233396,0.00022367736,0.000045276385,0.00004810869,0.000110455876,0.000009279262,0.00013421588,0.00012403874,0.0000036730796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003616058,0.00023484172,0.00019646437,0.000011337476,0.000022320655,0.00024931124,0.0005484565,0.0000040755285,0.99781775,0.00012826856,0.000012042023,0.00041350216],"study_design_scores_gemma":[0.0019606345,0.0015347967,0.00009039473,0.0000139044505,0.000010514016,0.0025240711,0.0017806112,0.000018701061,0.9911524,0.0000891906,0.00056134944,0.00026342506],"about_ca_topic_score_codex":0.000029662497,"about_ca_topic_score_gemma":0.0000026499602,"teacher_disagreement_score":0.00879276,"about_ca_system_score_codex":0.000025809686,"about_ca_system_score_gemma":0.000059731105,"threshold_uncertainty_score":0.9121298},"labels":[],"label_agreement":null},{"id":"W1999194056","doi":"10.1152/jn.00342.2012","title":"Multiple components of eIF4F are required for protein synthesis-dependent hippocampal long-term potentiation","year":2012,"lang":"en","type":"article","venue":"Journal of Neurophysiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Anisomycin; Long-term potentiation; Neuroscience; Synaptic plasticity; Metaplasticity; Hippocampal formation; Biology; Protein biosynthesis; Hippocampus; Translation (biology); Messenger RNA; Biochemistry; Receptor","score_opus":0.02630634087655424,"score_gpt":0.254106900080707,"score_spread":0.2278005592041528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999194056","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945469,0.00015130923,0.0045248996,0.000036561632,0.00051622855,0.000203283,0.000015043185,0.0000024129386,0.0000033781616],"genre_scores_gemma":[0.99847966,0.000042241125,0.0007714397,0.00004950516,0.0005751808,0.000011608479,0.00001744407,0.000021909489,0.0000309931],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895877,0.00013736369,0.00042140225,0.00013264373,0.00012726555,0.00022258412],"domain_scores_gemma":[0.99885905,0.000032649223,0.00069158647,0.00015185772,0.0001811569,0.00008373007],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001255261,0.00012202111,0.00028505572,0.00005971021,0.000056584257,0.0000081497765,0.00017973133,0.00010105713,0.00001873213],"category_scores_gemma":[0.00022242274,0.00010225248,0.0002025398,0.000030362378,0.000041621264,0.000012249165,0.00005236054,0.000084882726,0.0000019100203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006187056,0.00019027996,0.0014623437,0.00005069642,0.00007129039,0.0000039734473,0.000017224704,0.00014997991,0.9964462,0.000010793398,0.000015288166,0.0009632156],"study_design_scores_gemma":[0.0006829561,0.0007748089,0.05376404,0.0000488469,0.000042371343,0.000051397168,0.000019622636,0.000067189256,0.944256,0.000055328273,0.00013312054,0.00010433177],"about_ca_topic_score_codex":0.0000018219677,"about_ca_topic_score_gemma":4.4586173e-7,"teacher_disagreement_score":0.052301697,"about_ca_system_score_codex":0.000010572804,"about_ca_system_score_gemma":0.00002597864,"threshold_uncertainty_score":0.41697353},"labels":[],"label_agreement":null},{"id":"W1999247993","doi":"10.1074/jbc.m605437200","title":"Role of Angiotensin II Type 1A Receptor Phosphorylation, Phospholipase D, and Extracellular Calcium in Isoform-specific Protein Kinase C Membrane Translocation Responses","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Robarts Clinical Trials; Western University","funders":"","keywords":"Protein kinase C; Diacylglycerol kinase; Cell biology; Phospholipase C; Phospholipase D; Biology; Angiotensin II; Gq alpha subunit; Extracellular; Signal transduction; G protein; Chemistry; Biochemistry; Receptor","score_opus":0.01408925552554685,"score_gpt":0.22579975541645747,"score_spread":0.21171049989091062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999247993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98347926,0.015901582,0.00031952772,0.00008323885,0.00004008622,0.000114635055,0.000011544683,0.0000038434646,0.000046273566],"genre_scores_gemma":[0.9967183,0.0006823505,0.0021133632,0.00001179273,0.00020475962,0.0000032274495,0.000050286973,0.000011376845,0.00020455326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883795,0.000056019093,0.0005740522,0.00021298538,0.00013949865,0.00017951825],"domain_scores_gemma":[0.99924105,0.000019104828,0.0003166077,0.00013390077,0.00021616157,0.00007317924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047258553,0.00015622585,0.0002681951,0.00003531929,0.000052101346,0.000012053214,0.00012349046,0.00031131378,0.00013385461],"category_scores_gemma":[0.00008218346,0.00012422923,0.00010694626,0.00013162509,0.00009555714,0.000008732259,0.000031874482,0.00016795186,6.130073e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012851278,0.00015758799,0.00042832465,0.000017264854,0.000013058078,0.0000067443443,0.000034808454,0.00006925018,0.99659055,0.000032197888,0.0000861842,0.0012788702],"study_design_scores_gemma":[0.00069433544,0.00040717807,0.00061410776,0.00006333886,0.000006521173,0.000035697445,0.00012702672,0.000023528806,0.9909449,0.00025030112,0.006686528,0.00014650969],"about_ca_topic_score_codex":0.000017643053,"about_ca_topic_score_gemma":0.0000014072208,"teacher_disagreement_score":0.015219232,"about_ca_system_score_codex":0.000022419577,"about_ca_system_score_gemma":0.00006381832,"threshold_uncertainty_score":0.5065921},"labels":[],"label_agreement":null},{"id":"W1999277077","doi":"10.1021/nn900488u","title":"Nanoscale Aggregation of Cellular β<sub>2</sub>-Adrenergic Receptors Measured by Plasmonic Interactions of Functionalized Nanoparticles","year":2009,"lang":"en","type":"article","venue":"ACS Nano","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Microstructural Sciences; Steacie Institute for Molecular Sciences","funders":"Canadian Institutes of Health Research","keywords":"Cardiac myocyte; Biophysics; Receptor; Materials science; Nanoparticle; Silver nanoparticle; Cell membrane; Raman scattering; Cell surface receptor; Adrenergic receptor; Membrane; Nanotechnology; Myocyte; Chemistry; Raman spectroscopy; Cell biology; Biochemistry; Biology; Optics","score_opus":0.008768175856142785,"score_gpt":0.21423035863818474,"score_spread":0.20546218278204195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999277077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996573,0.0012478926,0.0015075695,0.0000548261,0.00033613885,0.00011999276,0.000017876344,0.00001283525,0.0001299028],"genre_scores_gemma":[0.99889904,0.00024031934,0.0003132134,0.000048329523,0.00005880986,0.000010419206,0.00016834807,0.000015460622,0.00024607315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989116,0.00007591508,0.00037176575,0.00025295865,0.00021207692,0.00017565515],"domain_scores_gemma":[0.9992813,0.000016739185,0.00023433345,0.00023577723,0.0001723058,0.00005953384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001725226,0.00014416876,0.00020049715,0.00005932095,0.00006790804,0.000009710835,0.00012792519,0.00013023725,0.00008532099],"category_scores_gemma":[0.000066148044,0.0001408337,0.00013145132,0.00016425888,0.00004695367,0.000011666756,0.000024528754,0.0000586779,0.000005594089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016327189,0.00013172763,0.00006861426,0.00000777489,0.000047984126,2.4821557e-7,0.00003378308,0.00016159406,0.99167126,0.000121412166,0.0012857727,0.006306564],"study_design_scores_gemma":[0.0005445745,0.00043971246,0.00004907053,0.00003536689,0.00003403217,0.000002989052,0.000045688248,0.000041479398,0.99421734,0.00024616232,0.0042045913,0.00013900334],"about_ca_topic_score_codex":0.0000107935,"about_ca_topic_score_gemma":0.000007682788,"teacher_disagreement_score":0.006167561,"about_ca_system_score_codex":0.000018701483,"about_ca_system_score_gemma":0.0000543873,"threshold_uncertainty_score":0.57430315},"labels":[],"label_agreement":null},{"id":"W1999558966","doi":"10.1074/jbc.m300320200","title":"A G Protein-coupled Receptor Kinase Induces XenopusOocyte Maturation","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Heterotrimeric G protein; Germinal vesicle; Cell biology; Biology; G protein-coupled receptor kinase; G protein-coupled receptor; Oocyte; G protein; Signal transduction","score_opus":0.017526433500260893,"score_gpt":0.24096867455679205,"score_spread":0.22344224105653115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999558966","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970086,0.0009547166,0.0011285585,0.000052421958,0.00014336566,0.00008709205,0.0000037252782,0.0000062542713,0.00061521714],"genre_scores_gemma":[0.9953521,0.00015445694,0.003571757,0.000075886455,0.00046840083,0.0000064524916,0.000025613315,0.000011266706,0.0003340896],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895984,0.000071703886,0.0004067351,0.0002017946,0.00015591047,0.0002040214],"domain_scores_gemma":[0.9991755,0.0000123068585,0.00035358215,0.00014215695,0.00018448834,0.00013200213],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045743992,0.00016269767,0.00021907061,0.000016799248,0.00006560958,0.00003374447,0.00018780211,0.00032961168,0.00051690766],"category_scores_gemma":[0.00040664672,0.00011317941,0.00017348399,0.00007420735,0.000051857147,0.000006406524,0.00003016548,0.00022764217,0.0000059721096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019042999,0.00007104415,0.00005339791,0.00001682322,0.00003523842,0.000008152754,0.0000085070615,0.000009739423,0.9990607,0.000037145088,0.0001552903,0.00035355228],"study_design_scores_gemma":[0.00044950237,0.00035337798,0.000027983246,0.00003612041,0.0000084569165,0.00009431299,0.00009240416,0.0000052744513,0.9873413,0.00027107046,0.011164073,0.00015611763],"about_ca_topic_score_codex":6.4892e-7,"about_ca_topic_score_gemma":8.465658e-8,"teacher_disagreement_score":0.011719373,"about_ca_system_score_codex":0.00002331233,"about_ca_system_score_gemma":0.00008932528,"threshold_uncertainty_score":0.56597763},"labels":[],"label_agreement":null},{"id":"W1999659011","doi":"10.1097/01.wcb.0000050042.22945.e5","title":"<i>In Vivo</i> Measurement of Receptor Density and Affinity: Comparison of the Routine Sequential Method with a Nonsequential Method in Studies of Dopamine D <sub>2</sub> Receptors with [ <sup>11</sup> C]Raclopride","year":2003,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; TRIUMF","funders":"","keywords":"Raclopride; In vivo; Receptor; Concordance; Dopamine; Dopamine receptor; Positron emission tomography; Ligand (biochemistry); Nuclear medicine; Chemistry; Neuroscience; Physics; Internal medicine; Biology; Medicine; Biochemistry; Genetics","score_opus":0.018596208644879417,"score_gpt":0.27151065734216157,"score_spread":0.25291444869728213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999659011","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97369796,0.0034531641,0.02214819,0.00008628172,0.00027044414,0.0003139328,0.000014463005,0.0000021404103,0.000013413946],"genre_scores_gemma":[0.90493786,0.00039242028,0.09444337,0.00003861604,0.00013808958,0.000005980515,0.0000017990525,0.000032294447,0.0000095534815],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995984,0.0011950042,0.0013274336,0.00034734976,0.0008155227,0.0003306979],"domain_scores_gemma":[0.9972639,0.0000857777,0.0013590944,0.0003134021,0.00086865167,0.00010918727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035127082,0.00034911715,0.0013587595,0.00020776397,0.0000599536,0.000014671424,0.00026608666,0.00018092296,0.000024419376],"category_scores_gemma":[0.00044433374,0.00022587393,0.00024811696,0.0004256995,0.00019482036,0.000035172277,0.00011010117,0.00036738624,8.476113e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009899215,0.00044785184,0.007488492,0.0001159527,0.0007515143,0.000005161383,0.000779201,0.00555816,0.9827069,0.00013248032,0.000058848593,0.0009654917],"study_design_scores_gemma":[0.0045733433,0.00077069324,0.00033775164,0.00030096632,0.0006375985,0.00012719557,0.0009973195,0.00017512505,0.99131715,0.00008548879,0.00044825525,0.00022911892],"about_ca_topic_score_codex":0.000073087525,"about_ca_topic_score_gemma":0.00033287954,"teacher_disagreement_score":0.07229518,"about_ca_system_score_codex":0.000031078496,"about_ca_system_score_gemma":0.00033162071,"threshold_uncertainty_score":0.9210871},"labels":[],"label_agreement":null},{"id":"W1999762137","doi":"10.1159/000137262","title":"Muscarinic Receptors of the Pancreas: a Correlation between Displacement of ( <sup>3</sup> H)-Quinuclidinyl Benzilate Binding and Amylase Secretion","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Quinuclidinyl Benzilate; Muscarinic acetylcholine receptor; Endocrinology; Internal medicine; Muscarinic antagonist; Amylase; Secretion; Receptor; Antagonist; Chemistry; Cholinergic; Biology; Enzyme; Biochemistry; Medicine","score_opus":0.016272292441968022,"score_gpt":0.25832769895961133,"score_spread":0.24205540651764332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999762137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981102,0.00024143237,0.00087281957,0.00005882217,0.00032541362,0.00025612875,0.000022130926,0.0000056865456,0.00010741112],"genre_scores_gemma":[0.9988799,0.0004977288,0.00016224291,0.000045982637,0.00015783774,0.000014978598,0.00006886968,0.000015071693,0.0001573704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898845,0.00016173495,0.00031791767,0.0002432644,0.00011567774,0.00017297833],"domain_scores_gemma":[0.99947023,0.000041872845,0.00023384964,0.00013880989,0.000057673104,0.000057583704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027660912,0.0001244685,0.00020635416,0.00004993687,0.0001054477,0.0000026117418,0.00010491273,0.00013816697,0.00021360289],"category_scores_gemma":[0.000027476319,0.000101595666,0.00008963159,0.000103809565,0.00012905042,0.000006048257,0.00012643238,0.0001043432,0.0000018653966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000109755114,0.000035133042,0.037275195,0.000029111146,0.00010629461,7.094071e-7,0.00032741204,0.0008292096,0.960026,0.000029479503,0.00045670985,0.00077496853],"study_design_scores_gemma":[0.001126437,0.0003729782,0.0045862123,0.000024623048,0.00014381499,0.000015677266,0.00013675651,0.0018451108,0.98783237,0.00003956335,0.0037332682,0.00014316224],"about_ca_topic_score_codex":0.000028108678,"about_ca_topic_score_gemma":0.0000015729822,"teacher_disagreement_score":0.032688983,"about_ca_system_score_codex":0.000016226102,"about_ca_system_score_gemma":0.000044853496,"threshold_uncertainty_score":0.4142951},"labels":[],"label_agreement":null},{"id":"W1999928356","doi":"10.1016/s0024-3205(01)01038-4","title":"M5 muscarinic receptors are needed for slow activation of dopamine neurons and for rewarding brain stimulation","year":2001,"lang":"en","type":"review","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Ventral tegmental area; Muscarinic acetylcholine receptor M4; Muscarinic acetylcholine receptor; Dopamine; Nucleus accumbens; Muscarinic acetylcholine receptor M1; Nicotinic agonist; Substantia nigra; Neuroscience; Stimulation; Chemistry; Muscarinic acetylcholine receptor M2; Dopamine receptor; Dopaminergic; Receptor; Endocrinology; Biology; Biochemistry","score_opus":0.07808839572915638,"score_gpt":0.35237229497560996,"score_spread":0.2742838992464536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999928356","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010190761,0.9313315,0.055121534,0.00022184307,0.0008905381,0.0020744442,0.00007687481,0.000018994715,0.00007348911],"genre_scores_gemma":[0.003722204,0.9887827,0.005495089,0.00014043937,0.0006782754,0.00017334397,0.000294193,0.000039313578,0.00067441206],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988407,0.000058397498,0.00035157002,0.0004365921,0.00012337427,0.00018935144],"domain_scores_gemma":[0.9990849,0.00020357301,0.00044367887,0.00013209083,0.00007680232,0.000058982587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058490847,0.0001835144,0.0004714858,0.00011057308,0.00017429412,0.000033564986,0.00017648979,0.0001949629,0.000007051395],"category_scores_gemma":[0.00078963,0.00014986472,0.0002038742,0.0002102034,0.000083138664,0.000010546706,0.000049515693,0.000049409104,1.8277038e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035574572,0.000031296797,0.000029029727,0.0033967963,0.000072562456,6.623278e-8,0.000040731353,0.00033944385,0.019550888,0.00013722619,0.0022018275,0.97416455],"study_design_scores_gemma":[0.00029035247,0.0005801986,0.000003199287,0.0012196703,0.0001104668,0.0000026088794,0.00020750792,0.000691087,0.006170528,0.00009304327,0.9903636,0.00026776522],"about_ca_topic_score_codex":0.000012099089,"about_ca_topic_score_gemma":0.0000032814503,"teacher_disagreement_score":0.98816174,"about_ca_system_score_codex":0.000009219721,"about_ca_system_score_gemma":0.00013025838,"threshold_uncertainty_score":0.6111306},"labels":[],"label_agreement":null},{"id":"W2000020160","doi":"10.3389/fendo.2013.00148","title":"How the Prohormone Theory Solved Two Important Controversies in Hormonal and Neural Peptide Biosynthesis","year":2013,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Fondation Jean-Louis Lévesque","keywords":"Proinsulin; Prohormone; Hormone; Amino acid; Biosynthesis; Insulinoma; Peptide Biosynthesis; Peptide; Melanocyte-stimulating hormone; Peptide hormone; Melanocortin; Insulin; Biochemistry; Chemistry; Prohormone convertase; Neuropeptide; Biology; Endocrinology; Gene; Receptor","score_opus":0.018037505760438517,"score_gpt":0.252854511097615,"score_spread":0.23481700533717645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000020160","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022188465,0.9951724,0.0007234964,0.00020021113,0.0005953376,0.0009638993,0.000032202075,0.000009206829,0.00008438982],"genre_scores_gemma":[0.0037307166,0.99380434,0.0011581,0.000105693034,0.00021923412,0.00032761518,0.000072464965,0.000053587668,0.0005282292],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99750507,0.00048895297,0.00053245184,0.0006616464,0.00011523422,0.0006966633],"domain_scores_gemma":[0.9990299,0.00013350675,0.00031572656,0.000423131,0.000029960134,0.00006780931],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003210301,0.00048185696,0.0011942938,0.0002278209,0.00007588368,0.00006731409,0.00046660038,0.0003386143,0.000016672697],"category_scores_gemma":[0.0002553656,0.00032492794,0.00026282298,0.0001213649,0.00035201688,0.000008064351,0.00026661344,0.0004836278,0.0000013519297],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011115997,0.000059939623,0.0005113209,0.00060783676,0.000458812,0.00009710306,0.00007249351,0.0000027584817,0.0027224028,0.0014889293,0.0037280554,0.9901392],"study_design_scores_gemma":[0.0010139885,0.0002717833,0.000034132925,0.00037546313,0.00026530898,0.0002149395,0.0007946265,0.00011597073,0.0010365675,0.0019997596,0.99319583,0.0006816033],"about_ca_topic_score_codex":0.00004350692,"about_ca_topic_score_gemma":0.000045170254,"teacher_disagreement_score":0.9894678,"about_ca_system_score_codex":0.000052055966,"about_ca_system_score_gemma":0.000103993996,"threshold_uncertainty_score":0.99992025},"labels":[],"label_agreement":null},{"id":"W2000124302","doi":"10.1124/mol.105.021246","title":"Agonist-Induced Cell Surface Trafficking of an Intracellularly Sequestered D1 Dopamine Receptor Homo-Oligomer","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Agonist; Receptor; Cell biology; 5-HT5A receptor; Cell membrane; Dopamine receptor D1; Cell; Cell surface receptor; HEK 293 cells; Endoplasmic reticulum; Biology; Chemistry; Biochemistry","score_opus":0.008453528951708353,"score_gpt":0.24897825142111968,"score_spread":0.2405247224694113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000124302","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98997164,0.000993214,0.007137195,0.00009217441,0.00058673095,0.0005003372,0.000030932966,0.00004161512,0.00064615544],"genre_scores_gemma":[0.99296767,0.000039051552,0.0053629656,0.00023906812,0.000391521,0.000035713132,0.0004034524,0.00008368626,0.0004768571],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977282,0.00033626956,0.0005240442,0.0006509094,0.00021928496,0.00054125604],"domain_scores_gemma":[0.9990124,0.0000154463,0.00026591177,0.00037983473,0.00017275299,0.0001536664],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034494748,0.00034644394,0.00038217823,0.00008454961,0.00010061616,0.00003647944,0.0003977879,0.00034856997,0.00053316646],"category_scores_gemma":[0.000009303184,0.00037218718,0.00018881385,0.0001737342,0.000094436386,0.000013417261,0.000113473354,0.0002198939,0.000024806248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014541538,0.00035996898,0.00003530459,0.000040062096,0.00006523545,0.000058917114,0.000035233577,0.0024628544,0.9956007,0.000068896086,0.00051970786,0.0006076876],"study_design_scores_gemma":[0.0015005799,0.00079303636,0.00001931642,0.000008979261,0.00007524441,0.000025333327,0.00004707102,0.0006326513,0.98692167,0.00003497521,0.009545252,0.00039590316],"about_ca_topic_score_codex":0.000093412804,"about_ca_topic_score_gemma":0.000011652734,"teacher_disagreement_score":0.009025544,"about_ca_system_score_codex":0.000033763743,"about_ca_system_score_gemma":0.00011557836,"threshold_uncertainty_score":0.999873},"labels":[],"label_agreement":null},{"id":"W2000284835","doi":"10.1007/s00018-015-1899-x","title":"Kir3 channels undergo arrestin-dependant internalization following delta opioid receptor activation","year":2015,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Internalization; δ-opioid receptor; Dynamin; Cell biology; Endocytic cycle; Receptor; Clathrin; G protein-coupled receptor; Arrestin; Biology; Chemistry; Endocytosis; Neuroscience; Signal transduction; Opioid; Biochemistry","score_opus":0.023515854417257422,"score_gpt":0.2576103751380052,"score_spread":0.2340945207207478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000284835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7181655,0.0013828792,0.2791244,0.00012532872,0.0006619543,0.00013138748,0.0000018490925,0.000016272648,0.0003903855],"genre_scores_gemma":[0.9959875,0.00008882832,0.0029833245,0.0004697256,0.00021548396,0.00001160557,0.0000841794,0.000018965335,0.00014042038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986323,0.00009590869,0.00020794534,0.00046901955,0.00033026366,0.00026452678],"domain_scores_gemma":[0.99940753,0.00000939734,0.000100302954,0.00016385349,0.0000788519,0.00024004935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006138907,0.00017104895,0.00014287276,0.0000770842,0.00018902568,0.000117730386,0.00022730073,0.00011450694,0.000018952665],"category_scores_gemma":[0.00028353895,0.00015428968,0.0000869012,0.00017442777,0.000096429976,0.000024200102,0.00012809815,0.0000600609,0.0000055054675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017483882,0.000018584771,0.00027375724,0.000008320795,0.00002461082,0.00000308338,0.00013638102,0.0005265425,0.9971598,0.00066457124,0.0004578841,0.0007089773],"study_design_scores_gemma":[0.00037172987,0.0002659758,0.0000054725965,0.000042923333,0.000015682295,0.0000035020032,0.000458337,0.0015424656,0.9863019,0.00094929186,0.009809105,0.00023363424],"about_ca_topic_score_codex":0.000045346264,"about_ca_topic_score_gemma":0.0000034915474,"teacher_disagreement_score":0.27782193,"about_ca_system_score_codex":0.000014183787,"about_ca_system_score_gemma":0.00018243115,"threshold_uncertainty_score":0.62917507},"labels":[],"label_agreement":null},{"id":"W2000463520","doi":"10.1021/bi4003869","title":"Efficacy as an Intrinsic Property of the M<sub>2</sub>Muscarinic Receptor in Its Tetrameric State","year":2013,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Muscarinic acetylcholine receptor; Property (philosophy); Chemistry; State (computer science); Crystallography; Thermodynamics; Stereochemistry; Biophysics; Receptor; Chromatography; Biochemistry; Mathematics; Physics; Philosophy; Biology; Epistemology; Algorithm","score_opus":0.007587984473879393,"score_gpt":0.21740047793265183,"score_spread":0.20981249345877243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000463520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99861366,0.00032855792,0.00001313815,0.00007169664,0.00014833192,0.00035126766,0.000011069994,0.000013097029,0.00044917446],"genre_scores_gemma":[0.9987839,0.00016467302,0.00011519865,0.00011846628,0.00013570458,0.000049557566,0.000050003255,0.000031417727,0.00055106776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868613,0.00006696836,0.0003283316,0.0004347586,0.00018127734,0.0003025473],"domain_scores_gemma":[0.9990697,0.000011246582,0.00014891675,0.0005415591,0.00011529613,0.00011330562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015098152,0.00020802332,0.00018975695,0.000026320637,0.00005122572,0.000030533614,0.00041674395,0.00019602718,0.00013919533],"category_scores_gemma":[0.0001639263,0.00013635348,0.00011778527,0.00019402281,0.00009037828,0.00000843477,0.00016887598,0.00017829218,0.000042636097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041625113,0.00013222994,0.00034546602,0.000040332827,0.00002093727,5.51447e-7,0.000047121724,0.00001691941,0.98611176,0.000003457153,0.00040956933,0.012830049],"study_design_scores_gemma":[0.0004781845,0.0001435309,0.0014966072,0.00004933355,0.000006055682,0.0000062606773,0.000086811146,0.0000329679,0.9967665,0.000033649783,0.0006870746,0.0002130163],"about_ca_topic_score_codex":0.00006104405,"about_ca_topic_score_gemma":0.000005382209,"teacher_disagreement_score":0.012617032,"about_ca_system_score_codex":0.000026617497,"about_ca_system_score_gemma":0.00016436967,"threshold_uncertainty_score":0.5560334},"labels":[],"label_agreement":null},{"id":"W2000517447","doi":"10.1016/j.coph.2014.03.002","title":"Ligand bias prevents class equality among beta-blockers","year":2014,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases","keywords":"BETA (programming language); Ligand (biochemistry); Class (philosophy); Chemistry; Computer science; Receptor; Biochemistry; Artificial intelligence","score_opus":0.1329177327090812,"score_gpt":0.43297337221030957,"score_spread":0.3000556395012284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000517447","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008761563,0.97987735,0.0003811831,0.000034074634,0.017655343,0.001017195,0.000068340894,0.000020987303,0.000069390706],"genre_scores_gemma":[0.00041731398,0.9950763,0.000061484636,0.00003363729,0.0025530627,0.00036924996,0.0012701899,0.00007186104,0.00014690074],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962134,0.001031165,0.0010574115,0.0009244323,0.00020432343,0.0005693133],"domain_scores_gemma":[0.9986395,0.00007961573,0.00065791723,0.00037334044,0.000058982914,0.00019060235],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009676431,0.0005766915,0.0013888731,0.0002098165,0.00007964575,0.000030414718,0.00058458495,0.0007136888,0.00024917533],"category_scores_gemma":[0.00004418947,0.00052463263,0.0005825004,0.00021056454,0.00012021403,0.000005621608,0.00034409898,0.00065485394,0.000051408926],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050588296,0.00045599905,0.00023576597,0.024176354,0.00052058033,0.0000018852842,0.00004711536,0.00002354219,0.0016843912,0.00019299763,0.082050115,0.8905607],"study_design_scores_gemma":[0.00064417836,0.00013668356,0.0000035752792,0.00253756,0.00019641298,0.000007367523,0.0000045064944,0.0000276535,0.0019004672,0.000034318095,0.9939907,0.0005165852],"about_ca_topic_score_codex":0.0000070947503,"about_ca_topic_score_gemma":0.0000018827631,"teacher_disagreement_score":0.9119406,"about_ca_system_score_codex":0.000080061465,"about_ca_system_score_gemma":0.00025796957,"threshold_uncertainty_score":0.9997205},"labels":[],"label_agreement":null},{"id":"W2000560379","doi":"10.1074/jbc.m109.056077","title":"Novel Translational Control in Arc-dependent Long Term Potentiation Consolidation in Vivo","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Norges Forskningsråd; Universitetet i Bergen","keywords":"Long-term potentiation; Consolidation (business); Term (time); In vivo; Arc (geometry); Chemistry; Memory consolidation; Cell biology; Biology; Biophysics; Neuroscience; Physics; Biochemistry; Mathematics; Business; Biotechnology; Receptor","score_opus":0.013903141973952517,"score_gpt":0.24759913004395276,"score_spread":0.23369598807000025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000560379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9717001,0.00029720078,0.0275062,0.00022494131,0.000046803685,0.000061795436,0.000008776338,0.0000019932395,0.00015219468],"genre_scores_gemma":[0.9990463,0.00009503674,0.00044580817,0.00015434418,0.00020307198,0.0000014331655,0.000026248425,0.0000034310704,0.000024293557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991174,0.00002985559,0.0004322937,0.0001476211,0.00012953756,0.0001433019],"domain_scores_gemma":[0.99959546,0.000016203081,0.00020392705,0.00006233463,0.00006938333,0.000052707837],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035523603,0.000099797486,0.00017330048,0.00003381154,0.000017388405,0.000015534823,0.000116656476,0.00021863633,0.00015219655],"category_scores_gemma":[0.00007085684,0.00008024056,0.000093056806,0.000053220716,0.000017361504,0.000007675792,0.000007481894,0.00016498873,3.9331755e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021095689,0.00015423514,0.012516951,0.0000047106146,0.000010150975,0.000012092806,0.000009351046,0.0006110859,0.9851421,0.000010210812,0.000007573187,0.0013105599],"study_design_scores_gemma":[0.0019618748,0.00018152122,0.050325226,0.00003501699,0.0000059704294,0.00009730104,0.000018354882,0.0001536379,0.94682413,0.00023831957,0.000048067926,0.00011055471],"about_ca_topic_score_codex":0.0000011525964,"about_ca_topic_score_gemma":0.0000025182646,"teacher_disagreement_score":0.038317967,"about_ca_system_score_codex":0.00002389327,"about_ca_system_score_gemma":0.00004559694,"threshold_uncertainty_score":0.3272115},"labels":[],"label_agreement":null},{"id":"W2000699330","doi":"10.1100/tsw.2007.223","title":"A Novel Dopamine Receptor Signaling Unit in Brain: Heterooligomers of D1 And D2 Dopamine Receptors","year":2007,"lang":"en","type":"review","venue":"The Scientific World JOURNAL","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"Dopamine receptor D2; Receptor; D1-like receptor; Dopamine receptor; Dopamine; D2-like receptor; Signal transduction; Cell biology; Phospholipase C; G protein-coupled receptor; Dopamine receptor D1; Gq alpha subunit; Biology; Chemistry; Neuroscience; Biochemistry","score_opus":0.050757393171287496,"score_gpt":0.31644151853133723,"score_spread":0.2656841253600497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000699330","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008083477,0.9873914,0.00095616333,0.00010108814,0.0027234566,0.0004971659,0.00004724555,0.0000076215238,0.00019234436],"genre_scores_gemma":[0.0016835242,0.98381865,0.002832053,0.000071435745,0.001113319,0.000016423262,0.00019776827,0.00010779541,0.010159039],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99672705,0.00030689652,0.0012421417,0.0006191868,0.0005058322,0.0005988701],"domain_scores_gemma":[0.99802387,0.00016085232,0.00091235305,0.00051022135,0.00019138977,0.00020133253],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.005035715,0.00047224274,0.001003262,0.0008336305,0.00037323788,0.00025124656,0.00076620805,0.00024173141,0.00030720953],"category_scores_gemma":[0.00019394077,0.0003202218,0.0004513285,0.00095097884,0.00044849998,0.000013728044,0.00025853855,0.00078940456,0.000009883764],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008738159,0.00016485417,0.000016588161,0.0016169002,0.00031193907,0.000013074912,0.00017992588,0.00005626253,0.4248637,0.00011656007,0.0012313029,0.5713415],"study_design_scores_gemma":[0.00045380392,0.000122313,0.0000013300264,0.003752014,0.00011856626,0.00026145903,0.00012810393,0.000005722796,0.021618225,0.000026799178,0.9731283,0.0003833204],"about_ca_topic_score_codex":0.0000113615415,"about_ca_topic_score_gemma":0.000064179425,"teacher_disagreement_score":0.97189707,"about_ca_system_score_codex":0.000046616537,"about_ca_system_score_gemma":0.00027895762,"threshold_uncertainty_score":0.99992496},"labels":[],"label_agreement":null},{"id":"W2000933426","doi":"10.1093/cvr/cvs152","title":"Emerging role of G protein-coupled receptors in microvascular myogenic tone","year":2012,"lang":"en","type":"review","venue":"Cardiovascular Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Heart, Lung, and Blood Institute","keywords":"Myogenic contraction; Mechanotransduction; G protein-coupled receptor; Vascular smooth muscle; Receptor; Autoregulation; Cell biology; Biology; Second messenger system; Blood vessel; Internal medicine; Vasoconstriction; Endocrinology; Signal transduction; Neuroscience; Medicine; Blood pressure; Smooth muscle","score_opus":0.056671080251077414,"score_gpt":0.36081662332874,"score_spread":0.30414554307766256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000933426","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022553469,0.9948729,0.00022481156,0.0000024253566,0.00021271557,0.0021168953,0.000010272296,0.000012139147,0.0002924829],"genre_scores_gemma":[0.0014132586,0.9958602,0.00047432104,0.0000017544584,0.000699925,0.00062904565,0.0002973263,0.0001866339,0.0004375214],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9939387,0.0016984035,0.00091798214,0.0010519461,0.0012365475,0.0011564544],"domain_scores_gemma":[0.997256,0.00003865399,0.00018146458,0.0019152496,0.00037869962,0.00022997257],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.007500224,0.0005490655,0.0022513787,0.00065587333,0.00012558783,0.000042490057,0.0009414435,0.00093615864,0.00020168377],"category_scores_gemma":[0.00025614322,0.00050322665,0.0038300927,0.0010182097,0.00017257305,0.000009353242,0.0006697424,0.0009609333,0.000071590934],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019466113,0.000096645505,0.0000038509747,0.006225264,0.0030339472,0.000017014647,0.000056960474,0.000025187139,0.04218301,0.00004730582,0.000037354734,0.948254],"study_design_scores_gemma":[0.0003479635,0.00009757475,5.2322696e-7,0.0024157779,0.00046094946,0.000040999803,0.00011167419,0.000005146647,0.04069458,0.000025141695,0.9553199,0.00047977423],"about_ca_topic_score_codex":0.00017630223,"about_ca_topic_score_gemma":0.000010746161,"teacher_disagreement_score":0.9552825,"about_ca_system_score_codex":0.00014783532,"about_ca_system_score_gemma":0.0005099934,"threshold_uncertainty_score":0.9997419},"labels":[],"label_agreement":null},{"id":"W2001514370","doi":"10.1016/j.neuropharm.2012.07.001","title":"An agonist at glutamate and dopamine D2 receptors, LY404039","year":2012,"lang":"en","type":"letter","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Agonist; Dopamine receptor D2; Endogenous agonist; Glutamate receptor; Chemistry; Neuroscience; Pharmacology; Dopamine; Receptor; D2-like receptor; Dopamine receptor; Dopamine receptor D3; Dopamine receptor D1; Medicine; Psychology; Biochemistry","score_opus":0.012333069922949028,"score_gpt":0.2620676256242602,"score_spread":0.2497345557013112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001514370","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9372034,0.0038076825,0.00010952691,0.04852592,0.008543624,0.0006993066,0.00019545924,0.000109909735,0.00080517126],"genre_scores_gemma":[0.196582,0.00430517,0.00054086297,0.74809957,0.029507954,0.0001642552,0.0041653407,0.00049541536,0.016139414],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972864,0.00044813266,0.00036585252,0.0009298633,0.0001912677,0.00077850977],"domain_scores_gemma":[0.99893963,0.00004274957,0.00023913177,0.00047573427,0.00007815123,0.00022457176],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018946061,0.00053043844,0.00045753788,0.00009795242,0.00023120442,0.00005150143,0.0004075883,0.0011147616,0.0018247428],"category_scores_gemma":[0.00002491387,0.00052080135,0.00013459948,0.00006500104,0.00018940541,0.0000075696225,0.00035024082,0.0008801903,0.00011469322],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070659946,0.000027481638,0.00007822571,0.000046969908,0.000052612766,0.00011648569,0.000012911983,0.0000029423288,0.63348156,0.0000027301896,0.36542213,0.00068527705],"study_design_scores_gemma":[0.00047966378,0.0004776227,0.000034648954,0.0000048773286,0.00010435863,0.00020817902,0.000003097745,0.000015520744,0.25283292,0.0000055402656,0.74543834,0.0003952667],"about_ca_topic_score_codex":0.000010294882,"about_ca_topic_score_gemma":0.000003210842,"teacher_disagreement_score":0.7406214,"about_ca_system_score_codex":0.000036637954,"about_ca_system_score_gemma":0.00005504131,"threshold_uncertainty_score":0.9997243},"labels":[],"label_agreement":null},{"id":"W2001544451","doi":"10.1016/j.cellsig.2006.05.020","title":"The V2 vasopressin receptor stimulates ERK1/2 activity independently of heterotrimeric G protein signalling","year":2006,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Heterotrimeric G protein; G protein-coupled receptor; MAPK/ERK pathway; Cell biology; G protein; HEK 293 cells; Scaffold protein; Signal transduction; Arrestin; Chemistry; Phosphorylation; Gq alpha subunit; Protein kinase A; Receptor; Biology; Biochemistry","score_opus":0.008399316026013966,"score_gpt":0.21227391882561603,"score_spread":0.20387460279960207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001544451","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8800659,0.0038588396,0.11511089,0.000027847002,0.00018863202,0.0004713515,0.000008850294,0.000028437253,0.00023925843],"genre_scores_gemma":[0.9959094,0.00007419945,0.002404215,0.000014071277,0.00048168044,0.000047202757,0.0000654085,0.00006521621,0.0009385894],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978408,0.00020336255,0.0005053757,0.00054060377,0.00040999972,0.00049985416],"domain_scores_gemma":[0.9988834,0.00007125741,0.00038623944,0.00039327223,0.00017681281,0.000088994195],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007262721,0.00033119653,0.00031571378,0.000062442385,0.0003800829,0.00011283297,0.00045961488,0.00026752517,0.00010959979],"category_scores_gemma":[0.000055018347,0.00026052466,0.00027529788,0.00017522462,0.000117338,0.00001447822,0.0001369445,0.0002628181,0.00001391527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013490344,0.00008688363,0.00011810315,0.000037246013,0.00008002442,0.000003400802,0.00002082625,0.0093500605,0.9877151,0.00015740136,0.00006113486,0.0022349025],"study_design_scores_gemma":[0.0004340266,0.00021673246,0.000018429162,0.00008285265,0.000031556017,0.0000018566691,0.000036737103,0.0033829506,0.9922736,0.00054523017,0.0026628885,0.00031312509],"about_ca_topic_score_codex":0.00011503024,"about_ca_topic_score_gemma":0.0000099283625,"teacher_disagreement_score":0.11584352,"about_ca_system_score_codex":0.000025860336,"about_ca_system_score_gemma":0.0000924633,"threshold_uncertainty_score":0.9999847},"labels":[],"label_agreement":null},{"id":"W2001893704","doi":"10.1016/s0166-2236(03)00022-5","title":"Receptor tyrosine kinase transactivation: fine-tuning synaptic transmission","year":2003,"lang":"en","type":"review","venue":"Trends in Neurosciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Transactivation; Autophosphorylation; Receptor tyrosine kinase; Neuroscience; Receptor Protein-Tyrosine Kinases; Cell biology; Biology; Tropomyosin receptor kinase C; Neurotransmission; Protein kinase A; Platelet-derived growth factor receptor; Receptor; Kinase; Transcription factor; Biochemistry; Growth factor","score_opus":0.04945501189271511,"score_gpt":0.3228640070369795,"score_spread":0.27340899514426437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001893704","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003018042,0.9952169,0.0025256183,0.000027407033,0.0011294086,0.00018158073,0.000021078551,0.000018921733,0.0005772714],"genre_scores_gemma":[0.0007387128,0.9954582,0.000980271,0.000045749344,0.00012352518,0.00005076096,0.00012032535,0.00004413492,0.0024383299],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977852,0.00025375962,0.0005095884,0.0008172585,0.00025734998,0.00037685747],"domain_scores_gemma":[0.99934465,0.000030976116,0.00019340988,0.00029810113,0.00002151365,0.00011133026],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034318253,0.00039386892,0.0006344275,0.00032621273,0.00014021357,0.00006689513,0.00043131624,0.00031399442,0.00039907842],"category_scores_gemma":[0.00003639682,0.00031237362,0.000305142,0.00084301195,0.000106145315,0.000010984398,0.00002459811,0.0002752378,0.0000052276787],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000067714473,0.00006192099,0.0000011643959,0.0004207219,0.0000086801365,0.000006998921,0.000016516358,0.000028632585,0.03417588,0.000032443797,0.0001650299,0.96507525],"study_design_scores_gemma":[0.00016958274,0.00029802206,8.107611e-7,0.0011938249,0.00005206337,0.000023219569,0.00000845556,0.000041913685,0.005930778,0.000008294733,0.9918822,0.0003908248],"about_ca_topic_score_codex":0.000004554847,"about_ca_topic_score_gemma":0.000003995185,"teacher_disagreement_score":0.99171716,"about_ca_system_score_codex":0.000022979228,"about_ca_system_score_gemma":0.00012927855,"threshold_uncertainty_score":0.9999328},"labels":[],"label_agreement":null},{"id":"W2001961299","doi":"10.1159/000139346","title":"Inhibition of the Natriuretic Action of the Imidazoline Receptor Agonist Moxonidine by Indometacin in the Rat","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Moxonidine; Agonist; Imidazoline receptor; Indometacin; Endocrinology; Chemistry; Internal medicine; Pharmacology; Medicine; Receptor; Enzyme inhibitor; Biochemistry","score_opus":0.01887022559966214,"score_gpt":0.27315070801425984,"score_spread":0.2542804824145977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001961299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99720913,0.00059546396,0.00012519429,0.0009660197,0.0006631526,0.00031877036,0.000019178055,0.0000023817256,0.00010068831],"genre_scores_gemma":[0.99848616,0.00042291178,0.00003195435,0.0007279399,0.00015492656,0.000031625823,0.000021207154,0.000009406204,0.000113844355],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998967,0.0003274259,0.00026635765,0.0001559292,0.00013848237,0.00014483221],"domain_scores_gemma":[0.9995079,0.000035716694,0.00019732416,0.00018020353,0.0000620135,0.000016812855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032063533,0.000100732024,0.00014046048,0.00002742656,0.00010724998,0.000002845096,0.0002481707,0.00011190437,0.000157958],"category_scores_gemma":[0.000047510905,0.0000544402,0.00011446557,0.00022032027,0.00017724947,0.000003700892,0.00007967822,0.0001759773,0.0000013803513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000098105185,0.0000944855,0.00044628384,0.000012606496,0.000020256371,3.6093857e-7,0.00012768261,0.0001320825,0.9912077,0.00003139394,0.007685079,0.00014396258],"study_design_scores_gemma":[0.00079262245,0.00009826258,0.00022164144,0.0000061846767,0.000027330398,0.000015610853,0.00008558554,0.000054923665,0.9872406,0.000044520046,0.011355214,0.000057492594],"about_ca_topic_score_codex":0.000024126457,"about_ca_topic_score_gemma":0.00001089364,"teacher_disagreement_score":0.003967089,"about_ca_system_score_codex":0.00001548198,"about_ca_system_score_gemma":0.00005995087,"threshold_uncertainty_score":0.22200069},"labels":[],"label_agreement":null},{"id":"W2002155047","doi":"10.1074/jbc.m211338200","title":"TM2-TM7 Interaction in Coupling Movement of Transmembrane Helices to Activation of the Angiotensin II Type-1 Receptor","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute","keywords":"Movement (music); Transmembrane protein; Transmembrane domain; Coupling (piping); Angiotensin II; Chemistry; Receptor; Biophysics; Biology; Materials science; Physics; Biochemistry; Metallurgy; Acoustics","score_opus":0.01957412055819836,"score_gpt":0.2559590699115647,"score_spread":0.23638494935336635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002155047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989268,0.00018060855,0.00047816325,0.00011701653,0.00012470693,0.00006178002,0.000002548932,9.2640835e-7,0.0001074576],"genre_scores_gemma":[0.99886537,0.000121177276,0.00079629896,0.00008272329,0.00008153234,9.533656e-7,0.0000041497046,0.000004672013,0.00004314366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925756,0.000029191597,0.00039566407,0.00010843837,0.00011354992,0.00009558135],"domain_scores_gemma":[0.99937624,0.00001913864,0.00030708298,0.000097416145,0.00016216651,0.000037944686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003306801,0.0000837954,0.00017947752,0.000019438086,0.000024072866,0.0000036803037,0.00012736437,0.00014707856,0.000117654236],"category_scores_gemma":[0.00019449934,0.000053143307,0.000118233176,0.000116618925,0.000026441554,0.0000042993565,0.000026591475,0.00012405997,1.8565993e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020476505,0.00008970437,0.00064624666,0.000017964068,0.000023651644,2.5190505e-7,0.00004551941,0.0014098489,0.9972426,0.0000088048255,0.000050280978,0.00026036185],"study_design_scores_gemma":[0.0002619091,0.00032792336,0.00029566305,0.00010149222,0.0000058442306,0.0000055662863,0.0002331798,0.000022122158,0.9971024,0.000044168864,0.0015394607,0.00006029453],"about_ca_topic_score_codex":0.0000043630466,"about_ca_topic_score_gemma":7.53645e-7,"teacher_disagreement_score":0.0014891798,"about_ca_system_score_codex":0.000021482865,"about_ca_system_score_gemma":0.000040887997,"threshold_uncertainty_score":0.21671212},"labels":[],"label_agreement":null},{"id":"W2002325209","doi":"10.1038/sj.bjp.0705176","title":"Characterization of a fluorescent conjugate of the rabbit angiotensin AT<sub>1</sub> receptor","year":2003,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"","keywords":"Yellow fluorescent protein; Agonist; Bisindolylmaleimide; Fusion protein; Protein kinase C; Molecular biology; Angiotensin II; Receptor; Confocal microscopy; Chemistry; Phospholipase C; Cell biology; Biology; Kinase; Biochemistry; Recombinant DNA","score_opus":0.0063974275897861485,"score_gpt":0.21809033542434497,"score_spread":0.21169290783455882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002325209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99719226,0.0009176196,0.0005442175,0.000116741845,0.0010358668,0.00013537289,0.0000324874,0.0000013877883,0.000024018516],"genre_scores_gemma":[0.9975482,0.0016726669,0.00025266362,0.00024560245,0.00020887879,0.000001889255,0.000013250401,0.000016133457,0.000040718554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880457,0.00027161668,0.0004912774,0.00012241074,0.00014688015,0.00016322146],"domain_scores_gemma":[0.99888796,0.0000121515795,0.0006291886,0.000065681714,0.0003481867,0.000056806995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040516138,0.00009296316,0.0002441254,0.00003672771,0.000058454807,0.0000069222096,0.00016421902,0.00011923486,0.0002206883],"category_scores_gemma":[0.00007537583,0.000087471824,0.00019748016,0.00008537925,0.00009668162,0.0000061608425,0.00005302831,0.00012684359,0.000001362341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013805088,0.00009079036,0.00015090308,0.000016830296,0.000108786175,0.000010918859,0.000025712927,0.000028162662,0.9946903,0.000018048102,0.0023365947,0.0023848922],"study_design_scores_gemma":[0.0010713567,0.00023378969,0.0006877374,0.00006185876,0.00006133254,0.0005324775,0.000011025696,0.000008827744,0.99000233,0.000015989126,0.007232012,0.00008127736],"about_ca_topic_score_codex":0.0000030024169,"about_ca_topic_score_gemma":0.0000033444205,"teacher_disagreement_score":0.0048954175,"about_ca_system_score_codex":0.000020636782,"about_ca_system_score_gemma":0.00010914435,"threshold_uncertainty_score":0.35669976},"labels":[],"label_agreement":null},{"id":"W2002756622","doi":"10.1016/j.bbrc.2011.05.037","title":"JWA regulates chronic morphine dependence via the delta opioid receptor","year":2011,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Natural Science Foundation of China; National Research Foundation; Norges Teknisk-Naturvitenskapelige Universitet","keywords":"Morphine; Chronic pain; Gene knockdown; Opioid; Addiction; Medicine; Mechanism (biology); Ubiquitin; Pharmacology; Receptor; Chemistry; Internal medicine; Apoptosis; Psychiatry; Gene; Biochemistry","score_opus":0.07006084641363625,"score_gpt":0.3255149389461393,"score_spread":0.25545409253250306,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002756622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98953617,0.0063690837,0.00085463026,0.001686254,0.00005697605,0.0004359158,0.00004901999,0.00003007966,0.0009818579],"genre_scores_gemma":[0.9935249,0.0028910504,0.002640494,0.00007514533,0.00024068479,0.000097737175,0.00021119982,0.000017759116,0.0003009995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985887,0.00020583144,0.00019838355,0.0003494748,0.0002838032,0.00037385421],"domain_scores_gemma":[0.99813575,0.00011348747,0.00004371887,0.0012738102,0.00025861576,0.0001746128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051420514,0.00014292666,0.00012505907,0.00003393302,0.00049868156,0.00004688278,0.0011888895,0.00015484242,0.00014906508],"category_scores_gemma":[0.00017562382,0.00009645494,0.00007020099,0.00022625823,0.00094896543,0.000008258802,0.0009941537,0.000406241,0.000053562686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003981712,0.00013027548,0.000024630262,0.000010738159,0.000026809408,2.638128e-7,0.000055477045,1.10859276e-7,0.99034613,0.0027529711,0.00217033,0.0044424655],"study_design_scores_gemma":[0.000154086,0.00028371724,0.00021417317,0.000020789652,0.000009547036,0.0000052717705,0.00006482915,0.0004698065,0.97483474,0.0027793234,0.021013675,0.00015002569],"about_ca_topic_score_codex":0.00021657397,"about_ca_topic_score_gemma":0.000022126624,"teacher_disagreement_score":0.018843345,"about_ca_system_score_codex":0.000024775905,"about_ca_system_score_gemma":0.00008795724,"threshold_uncertainty_score":0.39333186},"labels":[],"label_agreement":null},{"id":"W2002920996","doi":"10.1081/rrs-120014603","title":"METHIONINE PROXIMITY ASSAY, A NOVEL METHOD FOR EXPLORING PEPTIDE LIGAND–RECEPTOR INTERACTION","year":2002,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Benzophenone; Receptor; Chemistry; Peptide; Photoaffinity labeling; Combinatorial chemistry; Moiety; Ligand (biochemistry); Biochemistry; Biophysics; Stereochemistry; Biology; Organic chemistry","score_opus":0.0544042869002628,"score_gpt":0.2847840104363697,"score_spread":0.2303797235361069,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002920996","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.31738564,0.0006500849,0.67997557,0.0003620597,0.0013639372,0.00019598816,0.000009484418,0.000008084768,0.00004910686],"genre_scores_gemma":[0.8201926,0.0023659302,0.17402066,0.00009097365,0.0025838744,0.000047081136,0.000023645234,0.000054455944,0.00062077993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869156,0.000107420725,0.00050904666,0.00026343268,0.00021658077,0.00021198906],"domain_scores_gemma":[0.9990851,0.000060560273,0.00033445458,0.000088675464,0.00029391976,0.00013727725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011436032,0.00019821766,0.000299731,0.00013741673,0.00015574433,0.000058431586,0.00010140721,0.00016057317,0.00033574487],"category_scores_gemma":[0.00008998727,0.00016932325,0.00027999128,0.00010751693,0.000029842511,0.00007654865,0.000012989344,0.00023929146,0.0000011908336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003035359,0.000118053154,0.00002801313,0.000039419796,0.00012432032,3.728211e-7,0.00031487047,0.00045150644,0.9441995,0.00009205974,0.0009953536,0.053332973],"study_design_scores_gemma":[0.0011774643,0.0013922565,0.0000104597375,0.00008318858,0.00008956218,0.00018749402,0.0006315992,0.0020490089,0.90858454,0.00010811027,0.08546968,0.00021667039],"about_ca_topic_score_codex":0.0000061552028,"about_ca_topic_score_gemma":0.0000021938904,"teacher_disagreement_score":0.5059549,"about_ca_system_score_codex":0.00003259956,"about_ca_system_score_gemma":0.000021485626,"threshold_uncertainty_score":0.6904802},"labels":[],"label_agreement":null},{"id":"W2002952888","doi":"10.1002/bip.10359","title":"The NMR‐derived conformation of neuropeptide AF, an orphan G‐protein coupled receptor peptide","year":2003,"lang":"en","type":"article","venue":"Biopolymers","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Peptide; Orphan receptor; Neuropeptide Y receptor; G protein-coupled receptor; Neuropeptide; Receptor; Stereochemistry; Biochemistry; Gene; Transcription factor","score_opus":0.009121691355356822,"score_gpt":0.2238963644246786,"score_spread":0.2147746730693218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002952888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956245,0.0006357781,0.0017730033,0.000045439876,0.00022667497,0.00025602887,0.000010565442,0.000015183598,0.0014128344],"genre_scores_gemma":[0.99762124,0.00019834175,0.00086853723,0.00010703892,0.00008033687,0.000021356924,0.000076295706,0.000025842635,0.0010010052],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989379,0.00013243401,0.0002958905,0.00022010674,0.00016210225,0.00025159016],"domain_scores_gemma":[0.9992696,0.000011088758,0.00018240137,0.00034790148,0.00009016801,0.00009885811],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032939392,0.00015511969,0.00013007768,0.00002878336,0.0001891678,0.00002799284,0.00020497474,0.00010318375,0.00019487111],"category_scores_gemma":[0.000097302436,0.00011815158,0.00009152462,0.000087810804,0.00011855167,0.000010425821,0.000029119312,0.000066200024,0.00001612915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000740552,0.000021993055,0.000025155307,0.0000069315565,0.000025612508,3.199534e-7,0.000065388675,0.00001654895,0.9973352,0.0010253462,0.00020821368,0.0011952249],"study_design_scores_gemma":[0.000397582,0.00032495405,0.000026583511,0.000010263535,0.000008610319,0.0000033207434,0.000711516,0.00013493349,0.97295517,0.00002806486,0.025245566,0.00015341122],"about_ca_topic_score_codex":0.000046532605,"about_ca_topic_score_gemma":0.000015271895,"teacher_disagreement_score":0.025037352,"about_ca_system_score_codex":0.000009247475,"about_ca_system_score_gemma":0.0000783562,"threshold_uncertainty_score":0.48180816},"labels":[],"label_agreement":null},{"id":"W2003135973","doi":"10.1182/blood-2005-07-2903","title":"A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":221,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"National Institute of Allergy and Infectious Diseases; Amgen","keywords":"Cell biology; Immune system; T cell; Dendritic cell; Biology; Antigen-presenting cell; Inflammation; Exocytosis; Chemistry; Immunology; Biochemistry","score_opus":0.004993972683529228,"score_gpt":0.19680095964639097,"score_spread":0.19180698696286175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003135973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99608123,0.0016514063,0.0018926907,0.000027267084,0.00003413657,0.00023026638,0.00004832663,0.000003741054,0.000030955285],"genre_scores_gemma":[0.99641657,0.00016877413,0.0031713108,0.000019107836,0.00009188326,0.000008211203,0.000012857602,0.000018165065,0.000093143404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913967,0.000032967793,0.0003595832,0.00017241371,0.00014129688,0.00015404932],"domain_scores_gemma":[0.99952465,0.000022959408,0.000160754,0.00018503351,0.000046634905,0.0000599497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000237057,0.00011920029,0.00019644563,0.000020223444,0.0000474178,0.0000059719187,0.00016532464,0.00014564172,0.000024370687],"category_scores_gemma":[0.000010307519,0.00009161309,0.000105690175,0.000046874156,0.00005038934,0.0000043709915,0.000052780193,0.000075989396,4.6942526e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011632702,0.00007908364,0.0005907005,0.00009281544,0.000047361278,1.3659381e-7,0.00016576926,0.000012384511,0.9983203,0.0000065621944,0.000022145077,0.0006511456],"study_design_scores_gemma":[0.0011340778,0.000105978645,0.00016459913,0.000091003814,0.000076431854,0.0000021742965,0.000048828646,0.000024820303,0.99711055,0.000017878836,0.0011181511,0.000105495215],"about_ca_topic_score_codex":0.0000073317674,"about_ca_topic_score_gemma":0.0000015467297,"teacher_disagreement_score":0.0014826322,"about_ca_system_score_codex":0.000003429068,"about_ca_system_score_gemma":0.000042377833,"threshold_uncertainty_score":0.37358734},"labels":[],"label_agreement":null},{"id":"W2003437395","doi":"10.1016/j.cellsig.2011.10.018","title":"ßarrestin1-biased agonism at human δ-opioid receptor by peptidic and alkaloid ligands","year":2011,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; Université de Lausanne","keywords":"G protein-coupled receptor; Receptor; Etorphine; Chemistry; Endocytosis; Cell biology; DAMGO; G protein; μ-opioid receptor; Functional selectivity; Enkephalin; Opioid receptor; Biology; Agonist; Biochemistry; Opioid; (+)-Naloxone","score_opus":0.017143936727418676,"score_gpt":0.20652030129187912,"score_spread":0.18937636456446044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003437395","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98430634,0.0046807984,0.009545238,0.0000123663485,0.00023371732,0.00020055972,0.000017816095,0.000043186967,0.00095996103],"genre_scores_gemma":[0.99464786,0.0003444214,0.001803122,0.00014273096,0.0003380022,0.000023792038,0.00041766014,0.000071952454,0.0022104376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983356,0.000053118318,0.00034288928,0.0006333369,0.0001930992,0.00044197083],"domain_scores_gemma":[0.99921864,0.000013778772,0.00014900485,0.0003101714,0.00006755131,0.00024083756],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034305794,0.0003089401,0.00024955353,0.0000579371,0.00038464775,0.00004992263,0.00024837535,0.0002797914,0.0007810752],"category_scores_gemma":[0.00002531803,0.00031240802,0.00013115072,0.000078043464,0.00010157729,0.0000081845255,0.00016540223,0.00016320191,0.00004439319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044375116,0.00005018118,0.0004258019,0.000028148133,0.0000478174,0.000007999993,0.00030381727,0.0000052277987,0.9971568,0.00009103822,0.0014483371,0.00039047183],"study_design_scores_gemma":[0.0005410483,0.00033951987,0.000020462312,0.000042424494,0.000033272307,0.0000072510184,0.00009554439,0.00008266876,0.9852281,0.00023096603,0.012973841,0.00040490032],"about_ca_topic_score_codex":0.000040321404,"about_ca_topic_score_gemma":0.000006027727,"teacher_disagreement_score":0.011928683,"about_ca_system_score_codex":0.000022111732,"about_ca_system_score_gemma":0.000031718828,"threshold_uncertainty_score":0.9999328},"labels":[],"label_agreement":null},{"id":"W2003446134","doi":"10.1074/jbc.275.11.7862","title":"Subtypes of the Somatostatin Receptor Assemble as Functional Homo- and Heterodimers","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":519,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Somatostatin receptor 1; Somatostatin receptor; Internalization; Receptor; 5-HT5A receptor; Somatostatin receptor 2; Enzyme-linked receptor; Cell biology; Agonist; Somatostatin; Förster resonance energy transfer; G protein-coupled receptor; Chinese hamster ovary cell; Biology; Somatostatin receptor 3; Functional selectivity; Chemistry; Biophysics; Biochemistry; Endocrinology; Fluorescence","score_opus":0.011780128443167625,"score_gpt":0.221690587506691,"score_spread":0.20991045906352337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003446134","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981156,0.0008479851,0.00005026093,0.00012447099,0.00008184493,0.000030078192,0.0000071397853,0.000001916497,0.00074071344],"genre_scores_gemma":[0.99817795,0.00048093643,0.00041104475,0.00010742009,0.00019903664,0.0000010480072,0.0000071249024,0.000005608979,0.0006098202],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999318,0.000042046497,0.00027436877,0.00012698298,0.00012483209,0.00011374886],"domain_scores_gemma":[0.9995371,0.000022633221,0.00019127512,0.00010404843,0.00007875128,0.00006619573],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020272844,0.0000967937,0.00015497555,0.000006473915,0.000052608575,0.0000111326235,0.00014366402,0.0001636368,0.0014680781],"category_scores_gemma":[0.0000957508,0.00005594858,0.00013812019,0.000042383843,0.0001005307,0.0000034682512,0.00003844302,0.0001329914,0.000002619059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014795396,0.0000375719,0.0017376512,0.000009957202,0.000037041493,9.814349e-7,0.000009218621,0.000027443959,0.99560905,0.000006535027,0.00058577454,0.0017908356],"study_design_scores_gemma":[0.0002910613,0.00021079482,0.0015600519,0.000021657423,0.0000099002345,0.00012060227,0.00007019825,0.000003922162,0.98863,0.00016953533,0.008838514,0.00007377516],"about_ca_topic_score_codex":0.0000018786233,"about_ca_topic_score_gemma":1.4454818e-7,"teacher_disagreement_score":0.00825274,"about_ca_system_score_codex":0.000006504835,"about_ca_system_score_gemma":0.000047945807,"threshold_uncertainty_score":0.9994447},"labels":[],"label_agreement":null},{"id":"W2003568956","doi":"10.3791/2516","title":"Live-imaging of PKC Translocation in Sf9 Cells and in Aplysia Sensory Neurons","year":2011,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Protein kinase C; Cell biology; Diacylglycerol kinase; Biology; Signal transduction; Kinase; Gene isoform; Chromosomal translocation; Neuroscience; Chemistry; Biochemistry","score_opus":0.0287225432292349,"score_gpt":0.3479474252637028,"score_spread":0.3192248820344679,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003568956","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99680007,0.0016405272,0.0012839533,0.0000066092807,0.0001073091,0.00006623258,0.0000011001725,8.8917983e-7,0.000093306626],"genre_scores_gemma":[0.9972377,0.0004774117,0.0021833042,0.000042074542,0.00002965714,0.0000018434672,0.0000013643404,0.000010809573,0.000015875186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991945,0.000092136164,0.00039332913,0.00010903102,0.00010096136,0.00011001909],"domain_scores_gemma":[0.999638,0.00000601242,0.00019338216,0.000073076495,0.000044227923,0.000045280645],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002417617,0.00008391119,0.00018028666,0.000114353934,0.00001174993,0.0000059046843,0.00007699863,0.000050206432,0.000046283185],"category_scores_gemma":[0.00001235033,0.00007894766,0.00005388865,0.000050710776,0.000024671075,0.000009897431,0.000018453933,0.0000707523,4.870525e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023388382,0.00015185602,0.002673465,0.000008707525,0.000014524743,0.000010794974,0.0020306597,0.00001603929,0.9941564,0.000011881236,0.000009554798,0.0006822146],"study_design_scores_gemma":[0.0013134619,0.00017389862,0.0015116299,0.00005915859,0.0000062491154,0.000014294246,0.0010190681,0.00014620069,0.9955774,0.000040934,0.000065700115,0.000072013725],"about_ca_topic_score_codex":0.000036576483,"about_ca_topic_score_gemma":0.0000038289277,"teacher_disagreement_score":0.0014209729,"about_ca_system_score_codex":0.00000996302,"about_ca_system_score_gemma":0.00002859785,"threshold_uncertainty_score":0.32193923},"labels":[],"label_agreement":null},{"id":"W2003605443","doi":"10.3762/bjoc.9.24","title":"Development of peptidomimetic ligands of Pro-Leu-Gly-NH<sub>2</sub> as allosteric modulators of the dopamine D<sub>2</sub> receptor","year":2013,"lang":"en","type":"article","venue":"Beilstein Journal of Organic Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Peptidomimetic; Chemistry; Allosteric regulation; Bicyclic molecule; Pharmacophore; Stereochemistry; Dopamine; Dopamine receptor; Receptor; Neuroscience; Biochemistry; Peptide; Biology","score_opus":0.005871158631331667,"score_gpt":0.1951298306355269,"score_spread":0.18925867200419524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003605443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99826515,0.00079665805,0.00030481452,0.000059669357,0.00024194305,0.00024349718,0.0000086517175,0.000004900131,0.0000747175],"genre_scores_gemma":[0.9981242,0.00025838948,0.0011992035,0.000025057638,0.00022952397,0.000005434891,0.000015634858,0.000060533224,0.00008206841],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972261,0.0000524456,0.0014659181,0.00031953232,0.00059175125,0.00034424997],"domain_scores_gemma":[0.99695385,0.0000311324,0.0016311299,0.00051924697,0.0006709234,0.0001937377],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00054069835,0.0003509813,0.00064726226,0.00006123414,0.00007499042,0.000020909645,0.0006823411,0.0003192539,0.00028148075],"category_scores_gemma":[0.00025413625,0.00027203694,0.0003704607,0.00028885383,0.00015491682,0.000019614821,0.00028564202,0.0002837886,0.0000067903243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010770169,0.0001936781,0.0003091293,0.000297398,0.00027851068,0.0000018906394,0.00022948692,0.00003012507,0.9948006,0.0000019433207,0.00015146994,0.0035980628],"study_design_scores_gemma":[0.0011302889,0.00026730285,0.00026999673,0.00036143285,0.00008764051,0.000117182906,0.0004223801,0.000015470148,0.9968204,0.000035364792,0.00020059575,0.00027193484],"about_ca_topic_score_codex":0.000001933564,"about_ca_topic_score_gemma":0.0000011692775,"teacher_disagreement_score":0.003326128,"about_ca_system_score_codex":0.000065825385,"about_ca_system_score_gemma":0.0006475738,"threshold_uncertainty_score":0.9999732},"labels":[],"label_agreement":null},{"id":"W2003615351","doi":"10.1016/j.bmc.2004.01.007","title":"Solid phase synthesis of selective caspase-3 peptide inhibitors","year":2004,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Solid-phase synthesis; Peptide; Peptide synthesis; Combinatorial chemistry; Cleavage (geology); Chemical synthesis; Stereochemistry; Biochemistry; In vitro","score_opus":0.007944281794272536,"score_gpt":0.2795464635605887,"score_spread":0.2716021817663162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003615351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99623644,0.00073138985,0.0014266233,0.00013234299,0.00013605421,0.00011406005,0.00003083892,0.000022533697,0.0011696977],"genre_scores_gemma":[0.9983157,0.00011681842,0.0004654833,0.00008167788,0.000713871,0.000016477776,0.00005519688,0.000038394915,0.00019638691],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986098,0.000020540165,0.00037010148,0.00041205052,0.00027331835,0.00031422146],"domain_scores_gemma":[0.99915,0.000019736939,0.00018679402,0.00031999187,0.00014081433,0.00018268937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002176723,0.0002385137,0.00029928004,0.000028053524,0.00007790283,0.00000863966,0.00023240485,0.0002504879,0.00030181996],"category_scores_gemma":[0.0003392335,0.00022162337,0.00013958733,0.00016390116,0.00013416698,0.0000042113747,0.0000728142,0.00016423885,0.000009264858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095389936,0.00017573069,0.000036433226,0.00007416162,0.000086678614,0.000015156144,0.00008738123,0.000010805733,0.9980594,0.000009828392,0.00061470247,0.0007343692],"study_design_scores_gemma":[0.0011750954,0.00026319464,0.000017688953,0.00012025701,0.000073148134,0.00009149463,0.0004941476,0.0000044138915,0.9964894,0.000086103,0.0009560982,0.00022892987],"about_ca_topic_score_codex":0.000047832564,"about_ca_topic_score_gemma":0.000004144238,"teacher_disagreement_score":0.0020792338,"about_ca_system_score_codex":0.000063493746,"about_ca_system_score_gemma":0.00030858276,"threshold_uncertainty_score":0.9037539},"labels":[],"label_agreement":null},{"id":"W2003885057","doi":"10.1016/j.bbagen.2011.03.003","title":"Cleavage-resistant fusion proteins of the M2 muscarinic receptor and Gαi1. Homotropic and heterotropic effects in the binding of ligands","year":2011,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Muscarinic acetylcholine receptor; Cleavage (geology); Fusion protein; Chemistry; Biophysics; Fusion; Cell biology; Receptor; Computational biology; Biology; Biochemistry; Recombinant DNA; Philosophy","score_opus":0.011587892210648711,"score_gpt":0.21374532304372587,"score_spread":0.20215743083307716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003885057","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986823,0.0003223121,0.000019676918,0.00009220162,0.00014428144,0.00063043076,0.000019483485,0.0000067216165,0.000082601175],"genre_scores_gemma":[0.9985947,0.0003627533,0.00071261305,0.0000965363,0.00011291563,0.00004033213,0.00001793154,0.000027196194,0.0000350261],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985824,0.00021709106,0.0003213073,0.00040521155,0.00020147422,0.00027248487],"domain_scores_gemma":[0.9991919,0.000028557295,0.00024375421,0.00044021753,0.000037479822,0.000058134465],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021577039,0.00024771766,0.00029445498,0.00006931825,0.00011044754,0.000025835301,0.00033990396,0.00016945678,0.000005062242],"category_scores_gemma":[0.00004437297,0.00015507797,0.00013384402,0.00020766589,0.00018670413,0.000011186671,0.0002607655,0.00016045987,5.876201e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015899999,0.000112063695,0.0002329559,0.000112851165,0.000042128686,9.588667e-7,0.00074966624,3.66393e-7,0.99791443,0.00022915471,0.000032123215,0.0004142837],"study_design_scores_gemma":[0.00062714797,0.00093073765,0.036409643,0.00011473497,0.000035855715,0.000003464303,0.00008803545,0.000020510955,0.9614276,0.00013828355,0.000027421325,0.00017652659],"about_ca_topic_score_codex":0.00015060512,"about_ca_topic_score_gemma":0.00004758849,"teacher_disagreement_score":0.03648681,"about_ca_system_score_codex":0.000010365212,"about_ca_system_score_gemma":0.000046765235,"threshold_uncertainty_score":0.6323896},"labels":[],"label_agreement":null},{"id":"W2004207754","doi":"10.1074/jbc.m706531200","title":"Phosphatidylcholine Biosynthesis via CTP:Phosphocholine Cytidylyltransferase β2 Facilitates Neurite Outgrowth and Branching","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Canadian Institutes of Health Research","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Heart and Stroke Foundation of Canada","keywords":"Neurite; Cell biology; LY294002; Phosphocholine; Phosphorylation; Chemistry; Protein kinase B; Biology; Biochemistry; Phosphatidylcholine; In vitro; Membrane; Phospholipid","score_opus":0.010953979350065264,"score_gpt":0.23573122351257939,"score_spread":0.22477724416251413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004207754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.971263,0.005260401,0.02296363,0.00012412219,0.00012250511,0.00006619262,0.00002297471,0.000011150487,0.00016604399],"genre_scores_gemma":[0.9950438,0.001081185,0.0029562109,0.00026814293,0.0005291024,0.0000011805721,0.00002590085,0.000017865466,0.00007659818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984033,0.000039567927,0.0006726722,0.00032732173,0.00019178753,0.00036535584],"domain_scores_gemma":[0.99903524,0.0000945376,0.00024982094,0.00017446854,0.00015984091,0.00028606487],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009918642,0.00026610005,0.0003719628,0.000034817782,0.000100546386,0.00003692301,0.00024851292,0.0003458319,0.00016790339],"category_scores_gemma":[0.0003384841,0.0001950343,0.00023186379,0.00009665224,0.00013251591,0.00001141841,0.00006844595,0.00032959244,0.0000018160529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041141253,0.00009144237,0.002436544,0.0000373222,0.000056722925,0.00003798059,0.000038469196,0.000014340465,0.9893912,0.00000454345,0.000039018578,0.00744101],"study_design_scores_gemma":[0.00074643333,0.00032752543,0.0012239729,0.0000347498,0.000025748097,0.00028292756,0.00011322346,0.000023009788,0.99376935,0.00017225955,0.0030362126,0.00024456545],"about_ca_topic_score_codex":0.0000060255998,"about_ca_topic_score_gemma":9.5310156e-7,"teacher_disagreement_score":0.023780834,"about_ca_system_score_codex":0.000018954188,"about_ca_system_score_gemma":0.000031844447,"threshold_uncertainty_score":0.7953268},"labels":[],"label_agreement":null},{"id":"W2004659174","doi":"10.1074/jbc.m109.083139","title":"Modulation of the Human Glucuronosyltransferase UGT1A Pathway by Splice Isoform Polypeptides Is Mediated through Protein-Protein Interactions","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Glucuronidation; Gene isoform; Biochemistry; Immunoprecipitation; Chemistry; Alternative splicing; HEK 293 cells; Heterologous expression; Biology; Biophysics; Enzyme; Recombinant DNA; Gene; Microsome","score_opus":0.016209552064409063,"score_gpt":0.25456155608434033,"score_spread":0.23835200401993129,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004659174","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968789,0.00045322842,0.0016867508,0.0003638699,0.000041179912,0.00013871155,0.000040761606,0.000005310756,0.00039124166],"genre_scores_gemma":[0.9988844,0.00005486932,0.00042369348,0.00017682208,0.0002086201,0.00000392816,0.000041037012,0.0000079835345,0.00019868607],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989158,0.00004624759,0.0005089373,0.00018368199,0.00017103273,0.00017429367],"domain_scores_gemma":[0.9991701,0.000012033309,0.00039702922,0.00019744993,0.00015409013,0.00006929202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018202946,0.00016343652,0.00022063043,0.000010305923,0.000100730096,0.000013261256,0.00029581267,0.00021931565,0.00025046684],"category_scores_gemma":[0.00010656499,0.000101144025,0.00025683705,0.000086409695,0.00007334324,0.000012878033,0.00003349706,0.00026084675,9.604416e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000731935,0.00013381282,0.00011414879,0.000014512203,0.000033871504,0.0000012749744,0.00003494241,0.000010496553,0.9988382,0.000020338242,0.00021067617,0.0005145718],"study_design_scores_gemma":[0.0003657357,0.0003932647,0.00027529418,0.00006943514,0.000009788015,0.00002675358,0.00007474162,0.000010878647,0.994945,0.000868145,0.002836017,0.0001249352],"about_ca_topic_score_codex":0.000006728125,"about_ca_topic_score_gemma":3.4697263e-7,"teacher_disagreement_score":0.0038931498,"about_ca_system_score_codex":0.00002307542,"about_ca_system_score_gemma":0.000044443066,"threshold_uncertainty_score":0.41245335},"labels":[],"label_agreement":null},{"id":"W2004839284","doi":"10.1371/journal.pone.0076481","title":"High-Level Expression, Purification and Characterization of a Constitutively Active Thromboxane A2 Receptor Polymorphic Variant","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"National Institute of General Medical Sciences; National Institutes of Health; Manitoba Medical Service Foundation; Manitoba Health Research Council; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Thromboxane receptor; Receptor; Molecular biology; Chemistry; Biology; Thromboxane A2; Genetics","score_opus":0.02833751327731798,"score_gpt":0.20336867930852837,"score_spread":0.17503116603121038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004839284","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99339527,0.000056262932,0.0058583617,0.00014065769,0.000044819117,0.00032882663,0.000103961465,0.000008839158,0.00006298345],"genre_scores_gemma":[0.9914955,0.00023370548,0.0074701896,0.000052932606,0.00010705363,0.00006002807,0.00035630283,0.000012921548,0.00021135416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992967,0.000046034034,0.0001822746,0.00023553167,0.00012455543,0.0001149088],"domain_scores_gemma":[0.9994446,0.000008333439,0.00015554276,0.00015973703,0.00017483433,0.00005697493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006821382,0.00010322374,0.00016401258,0.000033413828,0.000058528683,0.000018115561,0.000073584815,0.00011978741,0.0003591685],"category_scores_gemma":[0.000050036866,0.000094350944,0.00002171412,0.000050071394,0.0000650655,0.000015254238,0.00004363127,0.000050756877,0.000012877914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035838566,0.00024127358,0.000095124386,0.000027072305,0.00007591085,1.5030703e-7,0.00008534475,3.160041e-7,0.99815106,0.00053785165,0.000020267677,0.00072979595],"study_design_scores_gemma":[0.00028446352,0.00013739866,0.005251102,0.00008626398,0.000026643567,0.0000012349869,0.000044623015,0.000027835642,0.9938593,0.00012311357,0.0000461436,0.00011191283],"about_ca_topic_score_codex":0.000033444237,"about_ca_topic_score_gemma":6.3087043e-7,"teacher_disagreement_score":0.005155978,"about_ca_system_score_codex":0.0000069413977,"about_ca_system_score_gemma":0.00003778396,"threshold_uncertainty_score":0.39326435},"labels":[],"label_agreement":null},{"id":"W2004872546","doi":"10.1182/blood-2004-10-3916","title":"Phosphorylation of RasGRP3 on threonine 133 provides a mechanistic link between PKC and Ras signaling systems in B cells","year":2005,"lang":"en","type":"article","venue":"Blood","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Diacylglycerol kinase; Protein kinase C; Phosphorylation; Cell biology; Biology; Signal transduction; Kinase","score_opus":0.010075031984450929,"score_gpt":0.22022899092923304,"score_spread":0.21015395894478212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004872546","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946397,0.001864868,0.002983428,0.00003498084,0.000059841936,0.00027231695,0.000013851013,0.000008739455,0.0001222527],"genre_scores_gemma":[0.9980116,0.000099465185,0.0013061633,0.000020350853,0.00041380175,0.00001640665,0.000034129258,0.000019640116,0.000078434445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991058,0.00004923193,0.00029023326,0.00026542982,0.00012230444,0.00016701329],"domain_scores_gemma":[0.99960476,0.000031270392,0.0001210263,0.00015030503,0.00004242984,0.000050194412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029632,0.00013311995,0.00020458712,0.000055811415,0.000036739893,0.000021335172,0.000081028964,0.00014608189,0.000014507844],"category_scores_gemma":[0.00003240657,0.00012464111,0.00004142831,0.00006425304,0.000018256118,0.000004108331,0.00003379086,0.00007891985,0.0000029596085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027779262,0.0000553499,0.00084616325,0.000054643126,0.0000347065,0.0000014261008,0.000065271175,0.00083330355,0.99562275,0.0003017739,0.0000069521966,0.0021498697],"study_design_scores_gemma":[0.00097225426,0.00038866108,0.00013222422,0.000106551284,0.000041640124,0.0000022950437,0.000054132568,0.0005748151,0.99691004,0.00013121696,0.00054578227,0.00014040274],"about_ca_topic_score_codex":0.000039875114,"about_ca_topic_score_gemma":0.0000080936,"teacher_disagreement_score":0.0033718874,"about_ca_system_score_codex":0.00000843889,"about_ca_system_score_gemma":0.00003127169,"threshold_uncertainty_score":0.5082717},"labels":[],"label_agreement":null},{"id":"W2004927455","doi":"10.1016/j.bbadis.2014.09.004","title":"Downregulation of G protein-coupled receptor kinase 2 levels enhances cardiac insulin sensitivity and switches on cardioprotective gene expression patterns","year":2014,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Centro Nacional de Investigaciones Cardiovasculares; Novo Nordisk; International Union of Biochemistry and Molecular Biology; European Foundation for the Study of Diabetes; Comunidad de Madrid; Fundación Ramón Areces","keywords":"Beta adrenergic receptor kinase; Downregulation and upregulation; Insulin resistance; Cardioprotection; Internal medicine; Endocrinology; Insulin receptor; Insulin; Cardiac function curve; Biology; Medicine; Heart failure; Receptor; Gene; G protein-coupled receptor; Myocardial infarction; Genetics","score_opus":0.00698252338078053,"score_gpt":0.22058359059321636,"score_spread":0.21360106721243582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004927455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921227,0.00018932419,0.006267158,0.000155764,0.00006362518,0.000744903,0.0004239589,0.000018482202,0.000014052363],"genre_scores_gemma":[0.9976875,0.00008348708,0.0016124405,0.00007432697,0.00014604343,0.00008792912,0.0002488519,0.000051770337,0.000007651852],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997799,0.00043017938,0.00037808268,0.000730652,0.00039606274,0.00026603756],"domain_scores_gemma":[0.9985171,0.000034749188,0.0003878895,0.0006378519,0.00020150661,0.00022092761],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003863956,0.0003715739,0.0004921245,0.00009947915,0.000087789675,0.00002923134,0.00015882937,0.00018513073,0.000008423525],"category_scores_gemma":[0.00019902301,0.0003445367,0.00036048918,0.0001240189,0.00012937635,0.000018045179,0.0001645322,0.000117445576,0.0000014602764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075359165,0.0002156552,0.000023294617,0.00015541512,0.0001554465,0.0000012340324,0.00006823697,0.00007592041,0.9973793,0.000058170113,0.000006258075,0.0011074466],"study_design_scores_gemma":[0.00058729126,0.00054089073,0.0070477864,0.00022633257,0.00010128851,2.851372e-7,0.000040244682,0.00017858483,0.99077797,0.000112269074,0.000014304277,0.00037274216],"about_ca_topic_score_codex":0.000040672836,"about_ca_topic_score_gemma":0.0000011767887,"teacher_disagreement_score":0.007024492,"about_ca_system_score_codex":0.000017770475,"about_ca_system_score_gemma":0.00008614483,"threshold_uncertainty_score":0.99990064},"labels":[],"label_agreement":null},{"id":"W2004962395","doi":"10.1074/jbc.m313310200","title":"Hetero-oligomerization between β2- and β3-Adrenergic Receptors Generates a β-Adrenergic Signaling Unit with Distinct Functional Properties","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Adenylyl cyclase; Agonist; Oligomer; Internalization; Receptor; Biophysics; Chemistry; Gs alpha subunit; Endocytosis; Ligand (biochemistry); Cell biology; Biochemistry; Biology","score_opus":0.03003170848644695,"score_gpt":0.21793151187409604,"score_spread":0.18789980338764908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004962395","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923088,0.0011096119,0.0062680445,0.00006446164,0.00008228553,0.000055014767,0.000007561625,0.000010769772,0.000093462644],"genre_scores_gemma":[0.9969923,0.00024102353,0.0015312865,0.000055481283,0.00095296843,0.000005514022,0.00011443602,0.00001921553,0.00008781386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988025,0.000047139078,0.00042637793,0.0002874396,0.00019969363,0.00023684624],"domain_scores_gemma":[0.999172,0.00001606733,0.00032920783,0.00011205151,0.00020028804,0.0001704225],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002315136,0.00023905734,0.0003048146,0.0000316463,0.00013830987,0.00005680342,0.00015076032,0.00025590035,0.00010769555],"category_scores_gemma":[0.00007889768,0.0001497311,0.000111480476,0.00011077639,0.00015575449,0.00001275589,0.00006443454,0.00020058134,9.0576566e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022060078,0.00004663501,0.0065600285,0.000024543662,0.00009864248,0.000008276142,0.000016284452,0.0032450508,0.989359,0.0000158099,0.000007622386,0.0003974859],"study_design_scores_gemma":[0.0008448865,0.0006814756,0.0010633634,0.00008478722,0.00004063406,0.00017614632,0.000092469025,0.000013190981,0.9959319,0.00017587331,0.00065279723,0.00024247666],"about_ca_topic_score_codex":0.0000039477272,"about_ca_topic_score_gemma":7.0928763e-7,"teacher_disagreement_score":0.00657288,"about_ca_system_score_codex":0.00002558439,"about_ca_system_score_gemma":0.000102116115,"threshold_uncertainty_score":0.6105857},"labels":[],"label_agreement":null},{"id":"W2005034350","doi":"10.1021/tx050040m","title":"Gene Expression Profiling in a Model of <scp>d</scp>-Penicillamine-Induced Autoimmunity in the Brown Norway Rat:  Predictive Value of Early Signs of Danger","year":2005,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Penicillamine; Autoimmunity; Drug; Gene expression; Gene expression profiling; Reverse transcriptase; Biology; Inflammation; Immunology; Pharmacology; Gene; Internal medicine; Polymerase chain reaction; Medicine; Immune system; Genetics","score_opus":0.06353149958084388,"score_gpt":0.3424874876843957,"score_spread":0.2789559881035518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005034350","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982396,0.0002645439,0.00032553033,0.00006506476,0.000021225178,0.00049963844,0.000015489963,0.0000019724025,0.0005669357],"genre_scores_gemma":[0.9974765,0.000072078634,0.0022037385,0.000020541345,0.000047440073,0.00010381528,0.000021716658,0.000015566131,0.000038595677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976349,0.00059108046,0.0005851633,0.00034205566,0.00037962897,0.00046716654],"domain_scores_gemma":[0.99872583,0.00050344854,0.00013652233,0.0003887887,0.00018843079,0.00005695409],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002133616,0.00013670509,0.00035484807,0.00021637339,0.000023880091,0.000004771061,0.00057528773,0.00044329005,0.00001202726],"category_scores_gemma":[0.001422888,0.00010959544,0.00007908086,0.0003790859,0.00025283036,0.000009821831,0.00033681814,0.0006240215,8.0065075e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020585278,0.0004388772,0.0006194561,0.000054069325,0.000010080615,0.0000026295613,0.0010658894,0.0034769208,0.9935523,0.00018022707,0.000027197222,0.00036645838],"study_design_scores_gemma":[0.0008905199,0.00070599123,0.0002987555,0.000075871656,0.0000028458505,0.0000017319826,0.00048083396,0.009778686,0.98722214,0.0004757613,0.000016209964,0.000050655028],"about_ca_topic_score_codex":0.000066706874,"about_ca_topic_score_gemma":0.000024535979,"teacher_disagreement_score":0.0063302037,"about_ca_system_score_codex":0.000070412025,"about_ca_system_score_gemma":0.000290065,"threshold_uncertainty_score":0.44691724},"labels":[],"label_agreement":null},{"id":"W2005193937","doi":"10.1016/j.bbamem.2011.01.012","title":"Structural and functional roles of small group-conserved amino acids present on helix-H7 in the β2-adrenergic receptor","year":2011,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; National Institutes of Health; Manitoba Health Research Council; National Center for Research Resources; National Institute of General Medical Sciences; Heart and Stroke Foundation of Canada","keywords":"G protein-coupled receptor; Transmembrane domain; Alanine; Receptor; Context (archaeology); Conserved sequence; Mutant; Amino acid; Transmembrane protein; Helix (gastropod); Biology; Agonist; Stereochemistry; Chemistry; Biochemistry; Peptide sequence; Gene","score_opus":0.030495827185023004,"score_gpt":0.2253872672312875,"score_spread":0.1948914400462645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005193937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99848086,0.00031940677,0.000015695377,0.00029376044,0.00019844678,0.00030091655,0.00009061026,0.000018039318,0.00028226103],"genre_scores_gemma":[0.99832296,0.00025433177,0.00034728862,0.00024954247,0.00029445894,0.000043042073,0.00032449703,0.000034847926,0.0001290086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819916,0.00022432834,0.00039586128,0.0005851034,0.00025379044,0.00034174247],"domain_scores_gemma":[0.99911934,0.000052877953,0.00021172292,0.0004613706,0.000066206776,0.00008846561],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002638045,0.00035574363,0.00031378624,0.00013851772,0.000110336194,0.000048023314,0.00038800095,0.00023258754,0.00012230557],"category_scores_gemma":[0.000026362946,0.00025217806,0.00018535323,0.00022643789,0.00025595585,0.000014651902,0.00014478678,0.00015620222,0.000007614135],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005661438,0.00017499966,0.000036185782,0.00005564677,0.00008781701,0.0000016405121,0.00040655347,0.0000060395755,0.9974415,0.00057644845,0.00010967455,0.0005374029],"study_design_scores_gemma":[0.0007321128,0.00074105785,0.01053131,0.00004403512,0.000034078443,0.000011163542,0.00031040388,0.00010365075,0.98648244,0.00021053026,0.00048241272,0.000316799],"about_ca_topic_score_codex":0.00012378412,"about_ca_topic_score_gemma":0.000044070108,"teacher_disagreement_score":0.010959002,"about_ca_system_score_codex":0.000010312869,"about_ca_system_score_gemma":0.000044902044,"threshold_uncertainty_score":0.999993},"labels":[],"label_agreement":null},{"id":"W2005579401","doi":"10.1016/j.ejmech.2014.09.083","title":"Fluorinated analogues of marsanidine, a highly α2-AR/imidazoline I1 binding site-selective hypotensive agent. Synthesis and biological activities","year":2014,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Turun Yliopistollinen Keskussairaala; Narodowym Centrum Nauki","keywords":"Indazole; Chemistry; Imidazoline receptor; Methylene; Agonist; Stereochemistry; Selectivity; Chemical synthesis; In vivo; In vitro; Medicinal chemistry; Pharmacology; Receptor; Organic chemistry; Biochemistry","score_opus":0.011846036734406977,"score_gpt":0.21178239043424565,"score_spread":0.19993635369983867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005579401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960566,0.0009012065,0.001721874,0.000088300454,0.0001010299,0.000040832827,0.000017127115,0.0000064728774,0.0010665485],"genre_scores_gemma":[0.9972765,0.00075417396,0.0010645167,0.000061256564,0.000709117,7.736725e-7,0.000022972446,0.000026460244,0.00008426057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985422,0.0002656104,0.000484754,0.00024669763,0.00023729683,0.00022342615],"domain_scores_gemma":[0.9987812,0.0001194283,0.0005267152,0.00014847897,0.0002535191,0.00017063293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010578026,0.00021464592,0.0004088027,0.00006490702,0.0000699777,0.000016088967,0.00021130548,0.000094404684,0.000056593508],"category_scores_gemma":[0.00094753935,0.00016449713,0.00013838665,0.00009687612,0.00017538367,0.000008370616,0.0000950961,0.00026165004,0.0000018791371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003011525,0.00004209496,0.0005206603,0.00005403098,0.00013363958,0.00006872059,0.00008526499,0.00002183461,0.99423397,0.000003550265,0.00049533165,0.004039757],"study_design_scores_gemma":[0.0006386762,0.00087109406,0.0009809149,0.00019854911,0.00008459177,0.0003600194,0.0004129414,0.000040006737,0.9944941,0.00001638124,0.001731335,0.00017139601],"about_ca_topic_score_codex":0.0000025128222,"about_ca_topic_score_gemma":2.593107e-7,"teacher_disagreement_score":0.0038683608,"about_ca_system_score_codex":0.000018500506,"about_ca_system_score_gemma":0.000041621137,"threshold_uncertainty_score":0.67079985},"labels":[],"label_agreement":null},{"id":"W2005596383","doi":"10.1074/jbc.m109.011700","title":"Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Selectivity; Chemistry; Nucleotide; Ligand (biochemistry); Stereochemistry; Biophysics; Biochemistry; Biology; Gene; Receptor","score_opus":0.00966305939525991,"score_gpt":0.24340785767612327,"score_spread":0.23374479828086336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005596383","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981477,0.00019219208,0.00078603526,0.00014639835,0.000054432276,0.000045302128,0.0000035762748,0.0000058963333,0.0006184574],"genre_scores_gemma":[0.9978587,0.00022810805,0.0013944859,0.00012923314,0.0003116503,5.858903e-7,0.000011507967,0.000007249589,0.000058478603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893886,0.00004767328,0.00040008107,0.00022046773,0.0001315515,0.00026135938],"domain_scores_gemma":[0.99942166,0.000024533441,0.00023895118,0.00011966742,0.000069898495,0.00012532022],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035844374,0.00015409004,0.00027481344,0.00003117317,0.000045278317,0.00002468693,0.0002472091,0.00029539366,0.00005070254],"category_scores_gemma":[0.00022795078,0.00011567103,0.00017820882,0.000114486866,0.00004413981,0.0000059311096,0.000042650292,0.00031090502,0.000001900028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012593584,0.00012300067,0.0038975358,0.00000535541,0.00001853176,0.000036131634,0.0000098248565,0.00008828261,0.9943342,0.000008796962,0.00006559029,0.001286772],"study_design_scores_gemma":[0.00046054096,0.00046182712,0.004584971,0.00004063942,0.0000070986325,0.0001222567,0.000038827293,0.000055585726,0.9931042,0.00044478313,0.0005176825,0.00016153915],"about_ca_topic_score_codex":9.238226e-7,"about_ca_topic_score_gemma":0.0000010932773,"teacher_disagreement_score":0.0012299935,"about_ca_system_score_codex":0.000045504097,"about_ca_system_score_gemma":0.000050289393,"threshold_uncertainty_score":0.47169274},"labels":[],"label_agreement":null},{"id":"W2005847898","doi":"10.1074/jbc.m802164200","title":"Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Allosteric regulation; Inhibitory postsynaptic potential; Entropy (arrow of time); Chemistry; Biology; Neuroscience; Biochemistry; Thermodynamics; Physics; Receptor","score_opus":0.01682134595382492,"score_gpt":0.24030037602717547,"score_spread":0.22347903007335054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005847898","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974395,0.001039544,0.0010261819,0.00006448469,0.00011382143,0.00012826115,0.000035280984,0.0000048224206,0.0001481184],"genre_scores_gemma":[0.9985181,0.00060837355,0.00027449286,0.00005920169,0.0002821284,0.000012208686,0.000031815674,0.000011640075,0.00020205746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987654,0.000093698276,0.0005418619,0.00020956948,0.00017265457,0.00021681757],"domain_scores_gemma":[0.99908394,0.000032680295,0.00048259905,0.00013417563,0.00015134114,0.00011525584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018989755,0.0001714368,0.0003565556,0.000033938897,0.000043244378,0.0000075965027,0.00021011657,0.0002103117,0.00033287075],"category_scores_gemma":[0.0001593064,0.00012816364,0.00018525301,0.00007670709,0.00009024485,0.0000090079775,0.00006269433,0.00030327204,0.000001594064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036252954,0.00025528364,0.00202396,0.000021308186,0.00006746073,0.00003541049,0.000050152972,0.00003376296,0.9965307,4.8935397e-7,0.00037278252,0.00024613584],"study_design_scores_gemma":[0.0011344688,0.00036244004,0.00029790573,0.000054604465,0.000010364517,0.00020043655,0.000093171766,0.000015426876,0.9944075,0.000009938009,0.0032722738,0.00014147018],"about_ca_topic_score_codex":0.000010245416,"about_ca_topic_score_gemma":0.0000018378628,"teacher_disagreement_score":0.0028994912,"about_ca_system_score_codex":0.000055040244,"about_ca_system_score_gemma":0.00007378556,"threshold_uncertainty_score":0.5226361},"labels":[],"label_agreement":null},{"id":"W2006228171","doi":"10.1210/me.2007-0041","title":"Differential Regulation of the Human Adrenocorticotropin Receptor [Melanocortin-2 Receptor (MC2R)] by Human MC2R Accessory Protein Isoforms α and β in Isogenic Human Embryonic Kidney 293 Cells","year":2007,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Melanocortin; Biology; Receptor; Gene isoform; Melanocortin receptor; HEK 293 cells; Cell biology; Transfection; ACTH receptor; Molecular biology; Adrenocorticotropic hormone; Cell culture; Endocrinology; Gene; Biochemistry; Hormone; Genetics","score_opus":0.007029098738904112,"score_gpt":0.2422508156325921,"score_spread":0.23522171689368798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006228171","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960655,0.00042654038,0.0019505452,0.000121031866,0.0002527561,0.00091487146,0.000047336493,0.000025636446,0.00019575635],"genre_scores_gemma":[0.99761987,0.000042991687,0.0002983262,0.000144885,0.00013295657,0.000078432415,0.00047474809,0.00007019879,0.0011375649],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971185,0.00023193898,0.00082365656,0.00075054116,0.0002773306,0.0007980768],"domain_scores_gemma":[0.9985805,0.000009692856,0.00047236934,0.0006749976,0.00009586911,0.00016652964],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001913788,0.0003952853,0.0004445765,0.00017618,0.00027421536,0.000035961915,0.00054037804,0.00037849543,0.00047749048],"category_scores_gemma":[0.000057955873,0.00034256995,0.00021898419,0.00020174557,0.00027826958,0.0000144527185,0.00040829187,0.00036475755,0.0000064743567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007740317,0.00014763509,0.0016719564,0.00005845529,0.00007864831,0.0000042665833,0.00005030225,0.000008892832,0.9951222,0.001265927,0.00072052295,0.00079382217],"study_design_scores_gemma":[0.0015179116,0.00045982967,0.0028843787,0.000056965724,0.000035991223,0.000010943685,0.000049227165,0.0000069126754,0.9899045,0.00048148842,0.004220242,0.00037159087],"about_ca_topic_score_codex":0.00013310523,"about_ca_topic_score_gemma":0.00011882337,"teacher_disagreement_score":0.0052176495,"about_ca_system_score_codex":0.000063670275,"about_ca_system_score_gemma":0.00006421534,"threshold_uncertainty_score":0.9999026},"labels":[],"label_agreement":null},{"id":"W2006381228","doi":"10.1016/j.cellsig.2004.05.012","title":"Role of specific protein kinase C isoforms in modulation of β1- and β2-adrenergic receptors","year":2004,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Heart and Stroke Foundation of Canada","keywords":"Gene isoform; Receptor; Adrenergic receptor; Protein kinase C; Cell biology; Protein kinase A; Chemistry; Signal transduction; Kinase; Biology; Biochemistry; Gene","score_opus":0.006759293265543901,"score_gpt":0.18998347797515724,"score_spread":0.18322418470961335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006381228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9766967,0.0027610941,0.02017178,0.000005952751,0.000043954296,0.00020125424,0.0000024428239,0.000004519629,0.00011226325],"genre_scores_gemma":[0.99555796,0.00015941288,0.0041022715,0.0000040697046,0.0000675252,0.000009164937,0.000049333095,0.000019819501,0.000030411398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990892,0.000028480192,0.000336287,0.000253095,0.00012746222,0.00016548732],"domain_scores_gemma":[0.9995979,0.000004390788,0.00014698792,0.00014825222,0.000055585184,0.00004687151],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024842896,0.00012691536,0.00018493483,0.00008731572,0.000030305093,0.000008600187,0.00009485228,0.00013858538,0.00004750413],"category_scores_gemma":[0.000013721235,0.0001232597,0.00006752003,0.00011856705,0.000044694767,0.000007022087,0.00004061407,0.00007083913,9.5200306e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046490793,0.000052213058,0.0002104279,0.00003532048,0.0000107913775,0.0000012696376,0.00015874956,0.014641954,0.98167133,0.00085407734,4.238181e-7,0.0023169233],"study_design_scores_gemma":[0.0005223267,0.00018497481,0.0000948545,0.00010368495,0.000004588057,9.855103e-7,0.0002205992,0.0007621621,0.99520606,0.0026284936,0.0001371505,0.00013413465],"about_ca_topic_score_codex":0.000052626154,"about_ca_topic_score_gemma":0.000008532162,"teacher_disagreement_score":0.018861253,"about_ca_system_score_codex":0.000014288697,"about_ca_system_score_gemma":0.000033210912,"threshold_uncertainty_score":0.50263846},"labels":[],"label_agreement":null},{"id":"W2006470810","doi":"10.1111/jnc.12157","title":"5‐Hydroxytryptamine type 7 receptor neuroprotection against NMDA‐induced excitotoxicity is PDGFβ receptor dependent","year":2013,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Neuroprotection; Receptor; Platelet-derived growth factor receptor; Enzyme-linked receptor; Excitotoxicity; Tropomyosin receptor kinase C; Biology; Interleukin-21 receptor; NMDA receptor; Agonist; Cell biology; Chemistry; Pharmacology; Growth factor; Biochemistry","score_opus":0.01194513049663834,"score_gpt":0.22759429989626553,"score_spread":0.2156491693996272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006470810","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971313,0.00017830542,0.0006556602,0.0002553322,0.0011191671,0.00019139417,0.000007246828,0.000015708436,0.00044588346],"genre_scores_gemma":[0.995142,0.00043279424,0.0009618729,0.0007429389,0.0016147303,0.000010159355,0.000021457314,0.000057767495,0.0010163231],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981263,0.00008420942,0.0006386657,0.00039380378,0.00041634458,0.00034067765],"domain_scores_gemma":[0.9981564,0.000017423428,0.0005880597,0.0003818768,0.000583852,0.00027236599],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022150943,0.00029841208,0.0003093164,0.00006584237,0.000117556156,0.00008898331,0.00042012156,0.0003112212,0.000933566],"category_scores_gemma":[0.00031195104,0.0002738563,0.00024484473,0.0001655198,0.000036112906,0.000026044156,0.00011429991,0.00051869947,0.000074976124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000106204556,0.00010141653,0.00008748635,0.00003465864,0.00005602155,0.0000062278496,0.000026562788,0.000033472894,0.9896106,7.4563087e-7,0.007756644,0.0021799612],"study_design_scores_gemma":[0.0005737297,0.0006515788,0.00023385574,0.000046965815,0.00001225692,0.00010602518,0.00008199336,0.000057579076,0.9881167,0.000025032416,0.009827728,0.00026660136],"about_ca_topic_score_codex":0.000007336214,"about_ca_topic_score_gemma":3.2416295e-7,"teacher_disagreement_score":0.0020710842,"about_ca_system_score_codex":0.000043402066,"about_ca_system_score_gemma":0.00012168194,"threshold_uncertainty_score":0.99997973},"labels":[],"label_agreement":null},{"id":"W2006519541","doi":"10.1016/j.yjmcc.2015.04.026","title":"Interplay between the E2F pathway and β-adrenergic signaling in the pathological hypertrophic response of myocardium","year":2015,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Internal medicine; Endocrinology; Phospholamban; Protein kinase A; Signal transduction; Chemistry; Adrenergic receptor; Receptor; Biology; Phosphorylation; Cell biology; Heart failure; Medicine","score_opus":0.016194900534242634,"score_gpt":0.24220052561613722,"score_spread":0.2260056250818946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006519541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9818771,0.009305955,0.008317283,0.00022796217,0.00011481087,0.00008665664,0.0000039694005,0.0000011857309,0.00006510014],"genre_scores_gemma":[0.99907863,0.00017855866,0.00029388268,0.0001991785,0.00022447966,0.0000031626569,0.000005246555,0.000011201841,0.0000056373974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99766284,0.0013862074,0.00040234247,0.00017686209,0.00018903145,0.0001826933],"domain_scores_gemma":[0.9992998,0.000101155674,0.00019807949,0.00020557581,0.000116778356,0.000078565216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0032600202,0.00014292441,0.00039406135,0.00006591629,0.00004289337,0.00001863443,0.0002440141,0.00019368692,0.0000016798627],"category_scores_gemma":[0.00025083966,0.000078459205,0.00019323439,0.00007603932,0.00017734025,0.0000044485378,0.00010812169,0.00025747382,2.3311755e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003977663,0.00001029845,0.0025592383,0.0000052259415,0.00008870614,0.00028047783,0.00022799417,0.00049143133,0.99525356,0.00009316005,0.000029267034,0.00056287664],"study_design_scores_gemma":[0.0014301648,0.0026368676,0.0025719912,0.00003382288,0.00014525575,0.001925259,0.0018872692,0.000032060914,0.98532265,0.0012871872,0.0025177235,0.00020976565],"about_ca_topic_score_codex":0.0000034285172,"about_ca_topic_score_gemma":2.886238e-7,"teacher_disagreement_score":0.017201575,"about_ca_system_score_codex":0.00000759941,"about_ca_system_score_gemma":0.0000740385,"threshold_uncertainty_score":0.31994733},"labels":[],"label_agreement":null},{"id":"W2006524318","doi":"10.1159/000133267","title":"Localization of the human gene for the type I cyclic GMP-dependent protein kinase to chromosome 10","year":2008,"lang":"en","type":"article","venue":"Cytogenetics and Cell Genetics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"","keywords":"Biology; Molecular biology; Gene; Complementary DNA; Somatic cell; Metaphase; Protein kinase A; genomic DNA; Intron; Chromosome; DNA; Gene mapping; Human genome; Genetics; Kinase; Genome","score_opus":0.01941984448200502,"score_gpt":0.24006255237146704,"score_spread":0.22064270788946203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006524318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98012275,0.0036315413,0.0151173,0.000047356036,0.000157286,0.0008054341,0.000028282713,0.0000044194226,0.00008564664],"genre_scores_gemma":[0.9955729,0.00086840783,0.0015915725,0.00017258768,0.00022400322,0.000052493844,0.000030248486,0.000038060265,0.0014497217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989986,0.00004087644,0.00026279062,0.00029582207,0.00017950982,0.00022242671],"domain_scores_gemma":[0.99912745,0.000010666975,0.00011109511,0.00047573372,0.00019033585,0.000084707935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013097932,0.00016882984,0.00013702351,0.000022681246,0.0003430596,0.000019562054,0.0002976669,0.00013238785,0.000036521837],"category_scores_gemma":[0.000024928178,0.00011701416,0.00008547152,0.00011321847,0.000101081154,0.000001084514,0.00018756182,0.000051001123,0.0000024776257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002442937,0.000043620385,0.00065545767,0.00002449444,0.000022251708,5.9444636e-7,0.000089105764,0.0030300927,0.9952469,0.000045318666,0.0002720308,0.0005456896],"study_design_scores_gemma":[0.00036221847,0.0005100428,0.00027903923,0.000009601565,0.00003799129,0.000008244928,0.000040276365,0.000382811,0.9769741,0.000119658136,0.02111378,0.00016220412],"about_ca_topic_score_codex":0.000006939921,"about_ca_topic_score_gemma":0.000011089978,"teacher_disagreement_score":0.020841748,"about_ca_system_score_codex":0.000008564964,"about_ca_system_score_gemma":0.00006737794,"threshold_uncertainty_score":0.4771699},"labels":[],"label_agreement":null},{"id":"W2006544103","doi":"10.1016/s0169-328x(00)00015-2","title":"Dopamine D-5 receptor modulates hippocampal acetylcholine release","year":2000,"lang":"en","type":"article","venue":"Molecular Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Notre-Dame; Université de Montréal; Douglas Mental Health University Institute; McGill University","funders":"Medical Research Council Canada; McGill University","keywords":"Dopamine; Neuroscience; Biology; D1-like receptor; D2-like receptor; Dopamine receptor; Dopamine receptor D1; Receptor; Acetylcholine; Hippocampal formation; Dopamine receptor D2; Neurotransmitter; Dopaminergic; Pharmacology; Central nervous system; Biochemistry","score_opus":0.02238526902770525,"score_gpt":0.3212108259347592,"score_spread":0.2988255569070539,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006544103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911846,0.0013556352,0.0015942614,0.0016589792,0.00008325086,0.00038724163,0.000023203267,0.000036296406,0.0036765612],"genre_scores_gemma":[0.98302007,0.00035705738,0.0025774096,0.0007134862,0.0004097969,0.000075325355,0.0003423738,0.0000868512,0.012417613],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969202,0.00051983807,0.00030330473,0.00075172813,0.00068171514,0.0008231925],"domain_scores_gemma":[0.99858433,0.00005099942,0.0000348847,0.00077456876,0.000244324,0.00031088715],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014428438,0.00024732694,0.00021290645,0.00013989666,0.00025115296,0.00010285727,0.00051738607,0.00022684588,0.0042653754],"category_scores_gemma":[0.0004199416,0.00024103383,0.00017204689,0.00039871482,0.00017344672,0.000007193179,0.00017576075,0.00042474316,0.0004947639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018588922,0.00009772389,0.000031170337,0.000015533598,0.00004493972,0.00003858184,0.0000290151,0.00049996213,0.95729625,0.000211227,0.0107808,0.030768892],"study_design_scores_gemma":[0.00070050627,0.0004248484,0.000033152548,0.000023223693,0.000004375283,0.00002231245,0.000050752882,0.00049273117,0.83373463,0.00038452577,0.16385186,0.0002770928],"about_ca_topic_score_codex":0.000053398762,"about_ca_topic_score_gemma":0.000006670449,"teacher_disagreement_score":0.15307106,"about_ca_system_score_codex":0.00003565748,"about_ca_system_score_gemma":0.000118093434,"threshold_uncertainty_score":0.99664485},"labels":[],"label_agreement":null},{"id":"W2006753722","doi":"10.1006/jtbi.2002.3036","title":"Construction of the Simplest Model to Explain Complex Receptor Activation Kinetics","year":2002,"lang":"en","type":"article","venue":"Journal of Theoretical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Kinetics; Simple (philosophy); Kinetic energy; Thermodynamics; Ligand (biochemistry); Statistical physics; Applied mathematics; Dimer; Biological system; Mathematics; Chemistry; Physics; Receptor; Classical mechanics; Biology; Biochemistry","score_opus":0.02496987517102433,"score_gpt":0.2613572256731796,"score_spread":0.23638735050215526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006753722","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89505553,0.00003774057,0.102488466,0.0015471573,0.00026645735,0.000091659655,0.000014828936,0.0000019353765,0.0004962091],"genre_scores_gemma":[0.98402274,0.000050241368,0.015310606,0.00037052005,0.0002075027,0.0000013045833,0.000005367908,0.000008935823,0.000022799668],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914855,0.00013288179,0.0003698713,0.00011176287,0.00009721403,0.00013973853],"domain_scores_gemma":[0.999307,0.000041037143,0.00024234403,0.00016015097,0.00017840535,0.000071076065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023059126,0.00009240672,0.00018027148,0.00004305482,0.000039498238,0.0000063046164,0.00023106435,0.00014721465,0.00044764398],"category_scores_gemma":[0.00035490742,0.000059296857,0.00013049306,0.000077428595,0.00029110844,0.0000027451424,0.000074523916,0.00011205124,0.0000026783912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008496326,0.00004246942,0.0000847854,0.0000033529232,0.000023104254,6.6223826e-8,0.000036106856,0.0005655778,0.9046363,0.09124004,0.0008372205,0.0024459818],"study_design_scores_gemma":[0.000308129,0.0007906142,0.00003339771,0.000018461848,0.000015881655,0.000025221982,0.0000724948,0.0017682303,0.97514755,0.017608985,0.0041248156,0.000086239204],"about_ca_topic_score_codex":5.0725873e-7,"about_ca_topic_score_gemma":2.8673344e-7,"teacher_disagreement_score":0.088967174,"about_ca_system_score_codex":0.000014549594,"about_ca_system_score_gemma":0.000015463176,"threshold_uncertainty_score":0.49013877},"labels":[],"label_agreement":null},{"id":"W2006802118","doi":"10.1124/jpet.110.172411","title":"Differential Signaling Defects Associated with the M201V Polymorphism in the Cysteinyl Leukotriene Type 2 Receptor","year":2010,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute for Health and Care Research","keywords":"Receptor; Polymorphism (computer science); B2 receptor; Differential (mechanical device); Medicine; Pharmacology; Immunology; Genetics; Biology; Genotype; Physics; Gene","score_opus":0.01344301049335546,"score_gpt":0.281460076091914,"score_spread":0.26801706559855853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006802118","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99672186,0.0017907912,0.00009378688,0.0004645922,0.0007763779,0.00011661865,0.0000017708218,0.0000021678784,0.000032036478],"genre_scores_gemma":[0.9977178,0.00012501502,0.00007808521,0.0015548341,0.0004575766,0.000004940105,0.000005329127,0.000013810098,0.000042617292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918354,0.00019154539,0.00019557778,0.00011032358,0.00014005696,0.00017896917],"domain_scores_gemma":[0.99957347,0.00006321188,0.00019194628,0.00007202336,0.000063551684,0.000035782512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000373653,0.00013052255,0.00014572222,0.00003404578,0.00014530029,0.000029631505,0.00022395902,0.00013231915,0.00017706527],"category_scores_gemma":[0.000007249402,0.00006856936,0.000059170747,0.00007876346,0.00013097556,0.000008063246,0.000033866017,0.00038698345,8.5345624e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049491524,0.00013906909,0.00020870562,0.000001289798,0.0001482536,0.000007497225,0.00062252954,0.000019330286,0.9978275,0.000047384772,0.00031169248,0.00017183552],"study_design_scores_gemma":[0.0014398411,0.001065046,0.00012256038,0.0000068379736,0.00006883056,0.000086461136,0.0007041384,0.000038920694,0.9919484,0.000021090627,0.004399474,0.00009839993],"about_ca_topic_score_codex":0.0000022264483,"about_ca_topic_score_gemma":0.000004575105,"teacher_disagreement_score":0.0058790976,"about_ca_system_score_codex":0.000012232203,"about_ca_system_score_gemma":0.00006195176,"threshold_uncertainty_score":0.27961773},"labels":[],"label_agreement":null},{"id":"W2006998486","doi":"10.1038/nature08650","title":"Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor","year":2010,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":469,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute of General Medical Sciences; Lundbeckfonden","keywords":"G protein-coupled receptor; Allosteric regulation; Chemistry; Ligand (biochemistry); Biophysics; Inverse agonist; Transmembrane protein; Receptor; Transmembrane domain; Binding site; Extracellular; Agonist; G protein; Salt bridge; Biochemistry; Biology","score_opus":0.0048439446781096615,"score_gpt":0.21073797392908003,"score_spread":0.20589402925097036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006998486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965066,0.0022349244,0.0003621878,0.00011593362,0.00045438166,0.00018332362,0.000010470014,0.0000040025316,0.00012823212],"genre_scores_gemma":[0.99604577,0.000035968227,0.0026787783,0.000017889273,0.00015132711,0.0000021809344,0.000024159179,0.000013634696,0.0010303223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937165,0.00002557856,0.00016892052,0.00017005591,0.00016555305,0.00009823427],"domain_scores_gemma":[0.9993134,0.000006468758,0.00015170687,0.0003614267,0.00014276686,0.000024220213],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021393005,0.00008781059,0.000109533496,0.000012707107,0.00004038007,0.000006159798,0.00020499344,0.00087234314,0.00017420374],"category_scores_gemma":[0.00005328666,0.00006216598,0.00010777495,0.000095955926,0.000048861795,0.0000023299472,0.000046116056,0.00054942234,0.0000016103033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003944519,0.00002129611,0.00011599879,0.000013053822,0.000011846479,6.353344e-8,0.000027551487,0.000043147676,0.99751127,0.0015100323,0.00039581006,0.00031048557],"study_design_scores_gemma":[0.00019775263,0.000045536315,0.00041765065,0.00001842097,0.000004805879,0.0000012837156,0.000019318915,0.000072176925,0.9754399,0.00021007462,0.02350324,0.000069826114],"about_ca_topic_score_codex":0.0000041661892,"about_ca_topic_score_gemma":0.0000058040614,"teacher_disagreement_score":0.02310743,"about_ca_system_score_codex":0.0000028136571,"about_ca_system_score_gemma":0.000032872646,"threshold_uncertainty_score":0.67283094},"labels":[],"label_agreement":null},{"id":"W2007149985","doi":"10.1074/jbc.m403363200","title":"Homodimerization of the β2-Adrenergic Receptor as a Prerequisite for Cell Surface Targeting","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":291,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Receptor; Adrenergic; Adrenergic receptor; β2 adrenergic receptor; Cell; Cell biology; Chemistry; Biology; Medicine; Pharmacology; Internal medicine; Biochemistry; Agonist","score_opus":0.010232215878942392,"score_gpt":0.2281481351275771,"score_spread":0.2179159192486347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007149985","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99287796,0.0010814538,0.005479091,0.000088041525,0.00015054416,0.00009011869,0.000014547379,0.0000029167952,0.00021529847],"genre_scores_gemma":[0.99292755,0.00021239917,0.0062732883,0.00006795944,0.00032022095,0.0000020726607,0.000028972909,0.000010480813,0.00015703267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991312,0.00003080112,0.00039653946,0.00015673443,0.00012471508,0.00015998395],"domain_scores_gemma":[0.9990804,0.000021094438,0.00049981737,0.00013016531,0.00020401922,0.000064496206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003033046,0.00012172678,0.00019416182,0.000006619773,0.00006617885,0.000011821488,0.00027525873,0.00023066084,0.00008792357],"category_scores_gemma":[0.00023320474,0.000074272684,0.00026944847,0.00007053943,0.000061182815,0.0000040446134,0.0000666245,0.00012163803,7.200426e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013059532,0.00007638358,0.00026530123,0.000031138374,0.000024102146,4.8571803e-7,0.00001956767,0.0022810963,0.9969758,0.000021892192,0.00011206551,0.00006156951],"study_design_scores_gemma":[0.00064183533,0.00036455455,0.00003475319,0.000036155066,0.00001526904,0.000016350932,0.00009568684,0.000011316304,0.9964394,0.00045194896,0.0017930878,0.00009963532],"about_ca_topic_score_codex":0.000002025641,"about_ca_topic_score_gemma":7.856186e-8,"teacher_disagreement_score":0.00226978,"about_ca_system_score_codex":0.000018691333,"about_ca_system_score_gemma":0.00010248931,"threshold_uncertainty_score":0.30287522},"labels":[],"label_agreement":null},{"id":"W2007227199","doi":"10.1016/j.mce.2010.12.030","title":"Adrenocorticotropin hormone (ACTH) effects on MAPK phosphorylation in human fasciculata cells and in embryonic kidney 293 cells expressing human melanocortin 2 receptor (MC2R) and MC2R accessory protein (MRAP)β","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Adobe Systems","keywords":"ACTH receptor; Phosphorylation; Melanocortin; MAPK/ERK pathway; Endocrinology; Internal medicine; Adrenocorticotropic hormone; Biology; Cell biology; Melanocortin receptor; Mitogen-activated protein kinase; Chemistry; Hormone; Medicine","score_opus":0.005542203669310933,"score_gpt":0.22485926871899714,"score_spread":0.2193170650496862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007227199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99566823,0.0023751284,0.000695505,0.00008927254,0.00017382464,0.0008354855,0.000015215452,0.000023133498,0.00012420179],"genre_scores_gemma":[0.9982491,0.00024163914,0.00068034464,0.00016102495,0.00009486337,0.0001205438,0.00020951408,0.00006314171,0.00017981199],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99747056,0.00025191196,0.00047263803,0.0009651968,0.00017307582,0.0006666484],"domain_scores_gemma":[0.9990754,0.000019679748,0.00019351613,0.00045098318,0.00003154107,0.0002288393],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020205117,0.00042550697,0.0004544871,0.0002499017,0.00018653923,0.000097649,0.00021228539,0.00040021108,0.000055193832],"category_scores_gemma":[0.000040877676,0.00043852947,0.000078708144,0.00012695414,0.00017179536,0.000022014385,0.00027887878,0.0005709591,0.000003996512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012058113,0.000097809716,0.00046077862,0.00009680348,0.000031033098,0.00012459967,0.00008326708,0.000015073532,0.99569505,0.00054265896,0.00005471109,0.0026776122],"study_design_scores_gemma":[0.0021929825,0.0006256659,0.0006672646,0.00009532806,0.000027585871,0.000018948243,0.00004456068,0.0000930959,0.99380535,0.00048101073,0.0014824786,0.00046571175],"about_ca_topic_score_codex":0.00012220518,"about_ca_topic_score_gemma":0.000057415193,"teacher_disagreement_score":0.0025808832,"about_ca_system_score_codex":0.00002232222,"about_ca_system_score_gemma":0.000041210296,"threshold_uncertainty_score":0.99980664},"labels":[],"label_agreement":null},{"id":"W2007397927","doi":"10.1016/s0166-2236(03)00081-x","title":"D1 and NMDA receptors hook up: expanding on an emerging theme","year":2003,"lang":"en","type":"review","venue":"Trends in Neurosciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Neuroscience; Hook; NMDA receptor; Theme (computing); Psychology; Receptor; Cognitive science; Biology; Medicine; Computer science; Biochemistry","score_opus":0.07996306052532016,"score_gpt":0.3812413401808644,"score_spread":0.30127827965554427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007397927","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009384232,0.9849003,0.00004357163,0.000010305035,0.003747683,0.0001927325,0.000014498947,0.000022257178,0.0016843958],"genre_scores_gemma":[0.0016382736,0.99486864,0.00014318532,0.000061992454,0.0001431782,0.000032127486,0.000040350555,0.000037487098,0.0030347903],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979227,0.0002437266,0.00035448035,0.00089282595,0.0002127028,0.00037354132],"domain_scores_gemma":[0.9993527,0.000024357758,0.00018727979,0.00031028458,0.000010765777,0.000114637056],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041620425,0.00035829982,0.0005374254,0.00033525532,0.0001629643,0.000104490966,0.0003706888,0.00021224338,0.00010014921],"category_scores_gemma":[0.00004989444,0.00027556176,0.00014745978,0.0004451559,0.00011370987,0.000011629444,0.00008644105,0.00022045508,0.0000023234472],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000045301254,0.000039199418,0.000019837878,0.00021448152,0.000006174274,0.000003865673,0.000056759338,0.0000069775397,0.0041248086,0.00012191545,0.00016287263,0.9952386],"study_design_scores_gemma":[0.00014416131,0.00055118644,0.000003369516,0.0008005143,0.000027297983,0.000020075253,0.00009338738,0.000015159626,0.0025897445,0.000033995424,0.9952516,0.00046953597],"about_ca_topic_score_codex":0.0000062430213,"about_ca_topic_score_gemma":0.0000071869595,"teacher_disagreement_score":0.9950887,"about_ca_system_score_codex":0.000015357551,"about_ca_system_score_gemma":0.0000524709,"threshold_uncertainty_score":0.99996966},"labels":[],"label_agreement":null},{"id":"W2007602714","doi":"10.1016/j.bpj.2012.11.284","title":"Probing G Protein-Coupled Receptor Signalling Complex Dynamics and Cellular Outcomes in Living Cells using Bioluminescence Resonance Energy Transfer (BRET)","year":2013,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Signalling; G protein-coupled receptor; Effector; Förster resonance energy transfer; Receptor; Signal transduction; Functional selectivity; Cell biology; Biology; G protein; Computational biology; Signalling pathways; Cell signaling; Second messenger system; Ligand (biochemistry); Chemistry; Biophysics; Biochemistry; Fluorescence; Physics","score_opus":0.011954122754242348,"score_gpt":0.21378989321024364,"score_spread":0.2018357704560013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007602714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90872175,0.00014250002,0.09073839,0.000056276,0.00010769941,0.00020894322,0.0000048668794,0.000008863978,0.00001073779],"genre_scores_gemma":[0.9940965,0.000061023893,0.005247845,0.000075047625,0.00032102986,0.000017141889,0.0000103449165,0.00003927976,0.00013178623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984472,0.00010793427,0.00041940334,0.0003829392,0.00020660454,0.0004359488],"domain_scores_gemma":[0.9994592,0.000025439547,0.00009998618,0.00013958036,0.000109103574,0.00016667251],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020369607,0.0002623173,0.0003218988,0.00007157206,0.0001851077,0.00015814211,0.00021077791,0.00016393073,0.00009500152],"category_scores_gemma":[0.000024885432,0.00022762589,0.00013477316,0.00012758038,0.000083259336,0.0000280431,0.000078840436,0.00023555598,0.0000033824465],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001998831,0.00008766879,0.00026012937,0.000019023406,0.000020961888,0.0000050578337,0.000055595734,0.0001403544,0.99800855,0.0002725447,0.000006188295,0.0011039271],"study_design_scores_gemma":[0.00033598754,0.00017331095,0.00014149566,0.00018269621,0.0000099809,0.000010987786,0.00011332661,0.087885976,0.9106857,0.00006830328,0.000070053684,0.00032213752],"about_ca_topic_score_codex":0.00011904173,"about_ca_topic_score_gemma":0.000014346062,"teacher_disagreement_score":0.08774562,"about_ca_system_score_codex":0.000055016044,"about_ca_system_score_gemma":0.000054986733,"threshold_uncertainty_score":0.9282315},"labels":[],"label_agreement":null},{"id":"W2007857391","doi":"10.1016/j.jcjd.2014.07.187","title":"Beta-Arrestin 2 Recruitment and Biased Agonism at the Free Fatty Acid Receptor GPR40","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Free fatty acid receptor 1; G protein-coupled receptor; Heterotrimeric G protein; Agonist; G protein; Receptor; Signal transduction; Cell biology; Internal medicine; Endocrinology; Chemistry; Biochemistry; Biology; Medicine","score_opus":0.023286599534399727,"score_gpt":0.22635658358169394,"score_spread":0.2030699840472942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007857391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993643,0.0038966958,0.00015456644,0.0014734766,0.000469811,0.0001226144,0.00003652294,0.0000018133235,0.00020148528],"genre_scores_gemma":[0.99758095,0.000046037476,0.0008977067,0.0007803602,0.00045759638,0.000008012168,0.000021311465,0.000020008452,0.0001880321],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990684,0.00012275921,0.00024558083,0.00015461326,0.00011025563,0.0002984158],"domain_scores_gemma":[0.9990067,0.000037775644,0.00017247314,0.00026463097,0.0000977152,0.00042070754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005892429,0.00013427432,0.00017855469,0.000055473924,0.00022029193,0.00006358324,0.0002839911,0.00008817474,0.0002628667],"category_scores_gemma":[0.00027819315,0.00009400295,0.00010564579,0.00004670162,0.00010663749,0.00000514696,0.000041027706,0.00012177828,0.0000065787012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000056242666,0.0000067475085,0.0118023,0.000009890382,0.000101123616,0.0000018466523,0.00009993502,0.000027068612,0.95878285,0.00009240446,0.016921388,0.012148826],"study_design_scores_gemma":[0.0005155146,0.00040350165,0.0031918087,0.000039925835,0.000042446893,0.000006906203,0.00006378232,0.000020144962,0.8030714,0.00033106245,0.19215457,0.00015893982],"about_ca_topic_score_codex":0.00008613233,"about_ca_topic_score_gemma":0.0025141032,"teacher_disagreement_score":0.17523319,"about_ca_system_score_codex":0.000037207275,"about_ca_system_score_gemma":0.00018770892,"threshold_uncertainty_score":0.3833329},"labels":[],"label_agreement":null},{"id":"W2007863280","doi":"10.1111/j.1471-4159.2004.02867.x","title":"Mutagenesis analysis of the serotonin 5‐HT2C receptor and a <i>Caenorhabditis elegans</i> 5‐HT2 homologue: conserved residues of helix 4 and helix 7 contribute to agonist‐dependent activation of 5‐HT2 receptors","year":2004,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Caenorhabditis elegans; Helix (gastropod); Mutagenesis; Serotonin; Biology; Agonist; Genetics; Conserved sequence; Serotonin Antagonists; Receptor; Mutation; Cell biology; 5-HT receptor; Gene; Base sequence; Zoology","score_opus":0.006614040819738328,"score_gpt":0.22225788145896536,"score_spread":0.21564384063922704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007863280","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975249,0.0007284648,0.00088413304,0.00041357006,0.00012447179,0.00017809749,0.00012386782,0.0000029830614,0.000019522768],"genre_scores_gemma":[0.9979426,0.0007778024,0.0009087127,0.00014181065,0.000085276544,0.0000057813572,0.000027179572,0.000020963811,0.00008984908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981684,0.00011745606,0.00084911776,0.00029672144,0.0003660081,0.00020228123],"domain_scores_gemma":[0.99779266,0.00007123802,0.0010907534,0.00033081693,0.0005691703,0.00014533293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043790776,0.00022267892,0.0006170682,0.00013021751,0.000077506724,0.000022227909,0.00031336007,0.00021653644,0.000032286585],"category_scores_gemma":[0.00043511004,0.00018280528,0.00028640663,0.00038586548,0.00015885044,0.000015110522,0.00014973947,0.00018443365,1.2003939e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000399939,0.0000962164,0.003027135,0.000121020785,0.0005305201,0.000004880566,0.00015752991,0.00066797243,0.99456686,0.000008752219,0.00013615873,0.00028301406],"study_design_scores_gemma":[0.0010079365,0.0005524053,0.006690507,0.00017269302,0.0003880666,0.000056919518,0.00029980124,0.000006778153,0.99021155,0.00003907479,0.00042171095,0.00015258834],"about_ca_topic_score_codex":0.00006758122,"about_ca_topic_score_gemma":0.000019087665,"teacher_disagreement_score":0.004355342,"about_ca_system_score_codex":0.00002942769,"about_ca_system_score_gemma":0.0001785391,"threshold_uncertainty_score":0.7454583},"labels":[],"label_agreement":null},{"id":"W2007898452","doi":"10.1016/j.cellsig.2007.05.001","title":"Receptor-coupling properties of the invertebrate visual guanine nucleotide binding protein iGqα","year":2007,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Receptor; G protein-coupled receptor; Biology; Biochemistry; G protein-coupled receptor kinase; 5-HT5A receptor; G protein; Muscarinic acetylcholine receptor M5; Enzyme-linked receptor; Phospholipase C; Cell biology; Molecular biology; Muscarinic acetylcholine receptor M3; Muscarinic acetylcholine receptor","score_opus":0.01424198066346587,"score_gpt":0.21498981066103637,"score_spread":0.2007478299975705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007898452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96619576,0.0011066349,0.03182357,0.000026452797,0.00031060068,0.00039220217,0.000002278068,0.000022595297,0.00011993205],"genre_scores_gemma":[0.99697846,0.000025326979,0.001592018,0.000045041215,0.0003439629,0.000010679762,0.000019977042,0.000058481768,0.00092602125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983466,0.000049280414,0.0004923865,0.0003888101,0.0002997992,0.00042310622],"domain_scores_gemma":[0.99922603,0.000009688661,0.00025706357,0.00027568074,0.00014101816,0.0000905443],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010370867,0.00023721813,0.00022360105,0.000070259244,0.00024264368,0.000040996365,0.00037092008,0.00019037277,0.000088410954],"category_scores_gemma":[0.000092173155,0.00017828844,0.00019731496,0.00021960467,0.00009625606,0.000009894922,0.00017498595,0.00020634165,0.000016280464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006622637,0.000042555163,0.00034926974,0.000051328254,0.00005030302,0.0000020667494,0.000099093886,0.00079424446,0.9980659,0.00018370882,0.000026378593,0.00026894012],"study_design_scores_gemma":[0.00026950028,0.00012364466,0.0000049105342,0.00020284951,0.000019050638,0.0000018150207,0.00032427293,0.0043480354,0.99378467,0.000023341152,0.00065298204,0.0002449179],"about_ca_topic_score_codex":0.000025403426,"about_ca_topic_score_gemma":0.0000127653775,"teacher_disagreement_score":0.030782757,"about_ca_system_score_codex":0.00002560043,"about_ca_system_score_gemma":0.000077689314,"threshold_uncertainty_score":0.72703916},"labels":[],"label_agreement":null},{"id":"W2007913250","doi":"10.1016/j.neures.2006.11.002","title":"Neurokinin-1 and neurokinin-3 receptors in primate substantia nigra","year":2006,"lang":"en","type":"article","venue":"Neuroscience Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Substantia nigra; Pars compacta; Substance P; Neurokinin A; Pars reticulata; Neurokinin B; Postsynaptic potential; Receptor; Excitatory postsynaptic potential; Biology; Inhibitory postsynaptic potential; Tachykinin receptor 1; Chemistry; Cell biology; Dopaminergic; Neuroscience; Neuropeptide; Dopamine; Biochemistry","score_opus":0.040512454404024886,"score_gpt":0.3458898990756299,"score_spread":0.305377444671605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007913250","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99757886,0.0002536374,0.00014648268,0.00023846883,0.00032791367,0.00021282914,0.0000040964233,0.000015025247,0.0012226679],"genre_scores_gemma":[0.99825597,0.00045163036,0.00015748209,0.00014850238,0.00011853681,0.00001887452,0.0000068260642,0.00002533699,0.0008168586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99751264,0.00028177508,0.00023433015,0.0007413258,0.0005358068,0.00069412036],"domain_scores_gemma":[0.99938196,0.00004465456,0.00004033475,0.00031953063,0.000093854025,0.00011968404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001108848,0.00014477521,0.0001330906,0.00025256025,0.00022675064,0.00015205306,0.00037507745,0.00010041195,0.000022726337],"category_scores_gemma":[0.0002597985,0.0001370503,0.000038398794,0.00072370627,0.0003360879,0.0000148679965,0.00025882295,0.00032543985,0.000007306239],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032854135,0.000045242665,0.009939446,0.000007875361,3.6469615e-7,0.000024289326,0.00001734354,0.000067597975,0.98733073,0.0005039985,0.0006457833,0.0013844913],"study_design_scores_gemma":[0.00057111925,0.000730097,0.042441647,0.000020713855,0.0000018849081,0.000050774775,0.00006962144,0.001122801,0.897256,0.000590611,0.056840617,0.0003040741],"about_ca_topic_score_codex":0.00010817929,"about_ca_topic_score_gemma":0.00005568836,"teacher_disagreement_score":0.09007468,"about_ca_system_score_codex":0.000012655162,"about_ca_system_score_gemma":0.00009708384,"threshold_uncertainty_score":0.55887496},"labels":[],"label_agreement":null},{"id":"W2008035364","doi":"10.1074/jbc.m112.395939","title":"Critical Hydrogen Bond Formation for Activation of the Angiotensin II Type 1 Receptor","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Receptor; Angiotensin II receptor type 1; 5-HT5A receptor; Enzyme-linked receptor; Asparagine; Hydrogen bond; Transmembrane domain; Protease-activated receptor 2; Mutant; Angiotensin II; Agonist; Residue (chemistry); Stereochemistry; Biophysics; Biochemistry; Amino acid; Biology; Molecule","score_opus":0.026282120658868216,"score_gpt":0.2697519330439871,"score_spread":0.2434698123851189,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008035364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968127,0.00043384533,0.0021680954,0.0002476864,0.00016836419,0.000058970272,0.00000787968,0.0000017116611,0.00010076954],"genre_scores_gemma":[0.996652,0.000039517352,0.0024886194,0.000092964685,0.0006525251,0.0000015821942,0.000018915913,0.0000054523116,0.000048403595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993979,0.000022636037,0.00027574733,0.000066248664,0.00009445379,0.00014302974],"domain_scores_gemma":[0.99932706,0.000034311604,0.00022607828,0.00009467602,0.00025757213,0.000060279643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031994612,0.000076353615,0.00012857027,0.0000074767263,0.00006871323,0.000005182043,0.00012882109,0.00020087014,0.000061656436],"category_scores_gemma":[0.0006289796,0.000045067307,0.00016840383,0.00004845086,0.00005138358,0.000010941137,0.000052344167,0.00008761921,4.0745175e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013189774,0.000060061826,0.0002553831,0.00001588941,0.000018278572,3.7385117e-8,0.00002327779,0.0000060080333,0.9974798,0.000042095315,0.0016168294,0.0003504503],"study_design_scores_gemma":[0.00018058432,0.00024124184,0.000112110654,0.00002328322,0.000013106895,0.000024540006,0.000067380955,0.000013004836,0.98623455,0.000169649,0.012859845,0.000060720417],"about_ca_topic_score_codex":2.4371568e-7,"about_ca_topic_score_gemma":1.8711296e-8,"teacher_disagreement_score":0.011245257,"about_ca_system_score_codex":0.000014717167,"about_ca_system_score_gemma":0.00002821569,"threshold_uncertainty_score":0.18377914},"labels":[],"label_agreement":null},{"id":"W2008250413","doi":"10.1021/ml500427r","title":"Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT<sub>2</sub> Receptor Ligands","year":2014,"lang":"en","type":"article","venue":"ACS Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Kjell och Märta Beijers Stiftelse; Knut och Alice Wallenbergs Stiftelse; Vetenskapsrådet; Stiftelsen för Strategisk Forskning","keywords":"Imidazole; Agonist; Substituent; Chemistry; Methylene; Stereochemistry; Biphenyl; Antagonist; Receptor; Derivative (finance); G protein-coupled receptor; Partial agonist; Combinatorial chemistry; Pharmacology; Biochemistry; Medicinal chemistry; Medicine; Organic chemistry","score_opus":0.004885806709513032,"score_gpt":0.1982484594449402,"score_spread":0.1933626527354272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008250413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970653,0.00006360314,0.0018361165,0.00060616067,0.00024354388,0.000072559415,0.000020564748,0.0000075922826,0.0000845429],"genre_scores_gemma":[0.9985236,0.000019655003,0.00007991406,0.00047753102,0.00037657467,0.000011113848,0.0003929433,0.000016400447,0.00010229726],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989293,0.000031195206,0.000243096,0.0003449439,0.00022642057,0.00022504422],"domain_scores_gemma":[0.9994776,0.000026979886,0.00013652486,0.0002133003,0.000047985035,0.000097599586],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001885593,0.00018051389,0.00019480498,0.000027539158,0.000068127105,0.000009067653,0.00014288697,0.00014724142,0.00014045888],"category_scores_gemma":[0.00006849613,0.00017385202,0.00008047568,0.00007155859,0.000102474245,0.000010092524,0.00008121335,0.00016245618,0.0000047774815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020390058,0.000020329124,0.0007993062,0.000048313424,0.000024738363,0.0000010195571,0.000055572604,0.000050267234,0.99012405,0.0000014845914,0.007836061,0.00083496585],"study_design_scores_gemma":[0.00084824604,0.000067997564,0.00029910452,0.00005065424,0.000014600538,0.000013386523,0.0000551889,0.00016929339,0.99757713,0.0000063277885,0.000727463,0.00017061143],"about_ca_topic_score_codex":0.000024453737,"about_ca_topic_score_gemma":0.000008227355,"teacher_disagreement_score":0.0074530845,"about_ca_system_score_codex":0.00006570087,"about_ca_system_score_gemma":0.00002859242,"threshold_uncertainty_score":0.70894796},"labels":[],"label_agreement":null},{"id":"W2008535001","doi":"10.1051/medsci/2010262165","title":"Découvertes récentes sur la fonction et la plasticité des voies dopaminergiques du cerveau","year":2010,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"Dopamine; Neuroscience; Dopamine receptor; Dopaminergic; Neurotransmitter; Glutamate receptor; D1-like receptor; Receptor; Biology; Dopamine receptor D1; Central nervous system","score_opus":0.023003767454634474,"score_gpt":0.29868538060704325,"score_spread":0.2756816131524088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008535001","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07662237,0.9013965,0.007149772,0.00021287845,0.001962936,0.0004998617,0.00011815553,0.000068932306,0.011968601],"genre_scores_gemma":[0.05364381,0.9366039,0.0050665597,0.00015612203,0.0011452937,0.000081159094,0.00014836303,0.00007874858,0.0030760434],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961555,0.000836818,0.00077195145,0.0010897875,0.0004655616,0.0006804075],"domain_scores_gemma":[0.9978334,0.0009231588,0.00049991376,0.00032163688,0.00023648492,0.00018546029],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021512837,0.0007651964,0.0009945688,0.00019670508,0.00065107126,0.0005029642,0.00084449723,0.0009281668,0.00040684483],"category_scores_gemma":[0.0010925207,0.0005866684,0.00054857443,0.00041183527,0.0015952666,0.000053301883,0.00032298118,0.00054495456,0.000040951545],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007403202,0.0011312861,0.007074569,0.0057677445,0.00047291353,0.00006460985,0.00034004767,0.00058361574,0.13901155,0.040037654,0.0051083975,0.80033356],"study_design_scores_gemma":[0.00046815583,0.0010223577,0.0002573611,0.0033577255,0.00024634114,0.0002492695,0.00014635157,0.0003314322,0.015559322,0.0013055655,0.97621095,0.0008451419],"about_ca_topic_score_codex":0.0003181864,"about_ca_topic_score_gemma":0.00032187556,"teacher_disagreement_score":0.9711026,"about_ca_system_score_codex":0.00003694017,"about_ca_system_score_gemma":0.0007619221,"threshold_uncertainty_score":0.99965847},"labels":[],"label_agreement":null},{"id":"W2008910889","doi":"10.1016/s0014-2999(00)00442-8","title":"Muscarinic receptor agonists decrease cocaine self-administration rates in drug-naive mice","year":2000,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Petroleum Technology Alliance Canada","keywords":"Pharmacology; Muscarinic acetylcholine receptor M4; Oxotremorine; Muscarinic acetylcholine receptor; Muscarinic acetylcholine receptor M1; Agonist; Chemistry; Muscarinic acetylcholine receptor M2; Partial agonist; Muscarinic agonist; Muscarinic acetylcholine receptor M3; Dopamine receptor D2; Dopamine receptor D3; Internal medicine; Endocrinology; Receptor; Medicine","score_opus":0.008533964588480134,"score_gpt":0.26994639052466823,"score_spread":0.2614124259361881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008910889","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99615234,0.0007882095,0.00015289885,0.00048532875,0.00056626083,0.000108114895,0.0000053284184,0.000007801955,0.0017336935],"genre_scores_gemma":[0.99433196,0.0013957766,0.0018642717,0.0009736212,0.0009331565,0.0000019685378,0.000024592717,0.00003136128,0.00044330055],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980948,0.0007978812,0.00054314145,0.00021298722,0.000111206115,0.00024000133],"domain_scores_gemma":[0.99933016,0.000028661323,0.00026217473,0.000086375854,0.00012047414,0.00017212855],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009894541,0.00016195675,0.00021048659,0.000081957674,0.000058750324,0.000024874462,0.0002699627,0.000047581172,0.0025692058],"category_scores_gemma":[0.00004204097,0.00015326153,0.00011567788,0.0000985522,0.00004381217,0.00001156371,0.000034361543,0.0002346573,0.00008295001],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006540028,0.00020737363,0.00012663522,0.000009991871,0.000085392334,0.00023989017,0.00015808303,0.00015663935,0.9840514,0.0000114132745,0.009695816,0.0046033324],"study_design_scores_gemma":[0.0023657917,0.00093323016,0.00040685738,0.00002264288,0.000054695527,0.00024599236,0.000076868346,0.00006019949,0.82148737,0.000015136191,0.17413971,0.00019149229],"about_ca_topic_score_codex":0.000003144268,"about_ca_topic_score_gemma":0.0000043509053,"teacher_disagreement_score":0.1644439,"about_ca_system_score_codex":0.000029138806,"about_ca_system_score_gemma":0.00017419829,"threshold_uncertainty_score":0.9983426},"labels":[],"label_agreement":null},{"id":"W2008969058","doi":"10.1016/j.schres.2008.08.036","title":"Genetic study of eight AKT1 gene polymorphisms and their interaction with DRD2 gene polymorphisms in tardive dyskinesia","year":2008,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Tardive dyskinesia; Antipsychotic; Dyskinesia; Haplotype; Psychosis; Schizophrenia (object-oriented programming); Genetics; Gene; Medicine; Allele; Biology; Internal medicine; Psychiatry; Disease; Parkinson's disease","score_opus":0.0316118696940288,"score_gpt":0.2821017256406837,"score_spread":0.2504898559466549,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008969058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971386,0.0016220624,0.00040050125,0.000054628406,0.00008871054,0.00059199263,0.000017102304,0.000008554752,0.00007784652],"genre_scores_gemma":[0.99714524,0.00042872992,0.001850657,0.000016912249,0.00023799816,0.00008012468,0.000037080383,0.00004758221,0.0001556828],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99769604,0.00035160544,0.0003673707,0.00064904545,0.00045658275,0.0004793715],"domain_scores_gemma":[0.998971,0.000041551866,0.000099841345,0.00050617213,0.00022953446,0.00015193032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004939406,0.00025649698,0.00032977667,0.00035795936,0.00022018481,0.000030996922,0.00030516714,0.00016259785,0.0000690952],"category_scores_gemma":[0.000038891496,0.00019699456,0.000059364425,0.00043584956,0.00021060959,0.000013760109,0.000255342,0.00034270974,0.0000064401243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017437986,0.00033968696,0.015627524,0.0000071778327,0.000092463146,0.000096976866,0.0008326783,0.00012218833,0.97873586,0.000015077579,0.000051690207,0.0023349004],"study_design_scores_gemma":[0.0030265725,0.0026262559,0.065698735,0.00003163052,0.000011055551,0.0002871457,0.0007197582,0.00014030097,0.92694277,0.00010770106,0.00012486857,0.0002832073],"about_ca_topic_score_codex":0.0005504658,"about_ca_topic_score_gemma":0.00027076234,"teacher_disagreement_score":0.05179307,"about_ca_system_score_codex":0.000035299996,"about_ca_system_score_gemma":0.00018070484,"threshold_uncertainty_score":0.8033205},"labels":[],"label_agreement":null},{"id":"W2009086729","doi":"10.1139/y05-127","title":"G-protein-coupled receptors signalling at the cell nucleus: an emerging paradigmThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell.","year":2006,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":166,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Hôpital Fleurimont; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Intracrine; Cell biology; Biology; Receptor; Rhodopsin-like receptors; Extracellular; Cell signaling; Intracellular; Signal transduction; Neuroscience; Biochemistry; Metabotropic receptor; Agonist; Paracrine signalling","score_opus":0.013407353842192006,"score_gpt":0.2557713682311975,"score_spread":0.2423640143890055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009086729","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.36103043,0.6338957,0.0000102650765,0.00021632416,0.0021633068,0.0011047825,0.000113969385,0.0000039271426,0.0014612951],"genre_scores_gemma":[0.21471973,0.7757349,0.00041299878,0.0008386038,0.0049547423,0.000069319256,0.00019441986,0.00016207159,0.0029131838],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971894,0.0007514593,0.0010763546,0.00040639975,0.00014032284,0.00043606077],"domain_scores_gemma":[0.9978548,0.00008842772,0.0014658191,0.00020210339,0.00017878355,0.0002100144],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008816749,0.0003734818,0.00110101,0.00025640358,0.00022621629,0.000022058834,0.0005464021,0.0005790766,0.061444156],"category_scores_gemma":[0.000022849268,0.00025677425,0.00039665832,0.00032221424,0.00031787093,0.000021704513,0.00006109511,0.00074031093,0.0000045765305],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015410181,0.000088780835,0.000009468562,0.0011011595,0.00021929537,0.0000072924786,0.0006770696,0.00017647671,0.98488545,0.00000687461,0.010093569,0.002580431],"study_design_scores_gemma":[0.0006843641,0.00052955875,0.0000027804263,0.00025699008,0.00046205998,0.000017002269,0.00012689091,0.000031470812,0.44104633,0.000063101754,0.5565286,0.00025081186],"about_ca_topic_score_codex":0.001121277,"about_ca_topic_score_gemma":0.0017491207,"teacher_disagreement_score":0.54643506,"about_ca_system_score_codex":0.00009135346,"about_ca_system_score_gemma":0.00096969894,"threshold_uncertainty_score":0.99998844},"labels":[],"label_agreement":null},{"id":"W2009252637","doi":"10.1074/jbc.m504562200","title":"Dopamine Receptor Oligomerization Visualized in Living Cells","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse","keywords":"Receptor; Dopamine receptor D1; Agonist; Biophysics; Dopamine receptor D2; Cell biology; Dopamine receptor; Chemistry; 5-HT5A receptor; Endogenous agonist; Dopamine; Transmembrane domain; Biochemistry; Biology; Neuroscience","score_opus":0.013259958656398485,"score_gpt":0.26402368239925034,"score_spread":0.25076372374285183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009252637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969139,0.00069291785,0.001793227,0.00007357896,0.00010314833,0.000039037495,0.0000032124567,0.000004503638,0.00037648718],"genre_scores_gemma":[0.9945122,0.0007703888,0.003465269,0.00011253395,0.00087091635,0.000002049617,0.00001534305,0.000010021458,0.00024126944],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990235,0.00005220386,0.0004545257,0.00016695207,0.00011695115,0.00018588526],"domain_scores_gemma":[0.99943304,0.00002967255,0.00026240293,0.00009849927,0.00008559783,0.000090763766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041271208,0.00012731286,0.00021803343,0.000026562124,0.000026108468,0.000017636485,0.00018368156,0.00023650934,0.0006733652],"category_scores_gemma":[0.00022260062,0.00009649651,0.00012495114,0.00008818696,0.000034708668,0.00000617767,0.000056426445,0.00016223744,0.000005749006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000074236545,0.000101873055,0.0006646298,0.000009237382,0.000013982425,0.0000028971951,0.000015996262,0.00016128027,0.99669206,0.0000032451062,0.0001497353,0.0021108328],"study_design_scores_gemma":[0.0003718392,0.00017056991,0.00018328804,0.000045868597,0.000004106446,0.000029008144,0.00006851257,0.0000548766,0.9847311,0.000011687516,0.014202465,0.00012668142],"about_ca_topic_score_codex":8.5589437e-7,"about_ca_topic_score_gemma":3.8913808e-7,"teacher_disagreement_score":0.01405273,"about_ca_system_score_codex":0.000029373714,"about_ca_system_score_gemma":0.000036708407,"threshold_uncertainty_score":0.73728764},"labels":[],"label_agreement":null},{"id":"W2009463518","doi":"10.1002/glia.20506","title":"G protein‐coupled receptor 84, a microglia‐associated protein expressed in neuroinflammatory conditions","year":2007,"lang":"en","type":"article","venue":"Glia","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":133,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Microglia; Proinflammatory cytokine; Tumor necrosis factor alpha; Experimental autoimmune encephalomyelitis; Receptor; Biology; Cell biology; Immunology; Neuroinflammation; Multiple sclerosis; Neuroscience; Inflammation; Biochemistry","score_opus":0.007683864522675148,"score_gpt":0.23252463622168779,"score_spread":0.22484077169901265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009463518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99736816,0.00013586486,0.0010429487,0.00008187721,0.00014771409,0.0007938303,0.00004050638,0.000039829156,0.0003492679],"genre_scores_gemma":[0.9965393,0.000008409037,0.0010483592,0.000106945605,0.0001669784,0.00013059414,0.00022024367,0.000039442355,0.0017397067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985779,0.00007739486,0.0003551015,0.00039387666,0.00015978715,0.00043597678],"domain_scores_gemma":[0.99937063,0.000009742134,0.00013521287,0.00028221306,0.0000913202,0.00011087929],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005008641,0.00019404895,0.00018173961,0.000082767125,0.00009755857,0.00003146734,0.00019063504,0.0002463167,0.000272573],"category_scores_gemma":[0.00017782963,0.00020348019,0.000098916,0.00014968844,0.000048423237,0.000007043521,0.00006621659,0.00017460348,0.000047876565],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009369091,0.00009229357,0.00021454952,0.000014606185,0.000021543983,0.000017026683,0.00005250281,0.000010382235,0.9986263,0.00015676093,0.0005403118,0.00016001098],"study_design_scores_gemma":[0.0009244065,0.00015721237,0.0006307375,0.00006690748,0.000005520892,0.0000020377895,0.00007879518,0.00005656615,0.9884781,0.00021957443,0.009131324,0.00024880446],"about_ca_topic_score_codex":0.000043334367,"about_ca_topic_score_gemma":0.000106783984,"teacher_disagreement_score":0.010148207,"about_ca_system_score_codex":0.0000370302,"about_ca_system_score_gemma":0.00008175673,"threshold_uncertainty_score":0.8297681},"labels":[],"label_agreement":null},{"id":"W2009657275","doi":"10.1371/journal.pone.0044324","title":"Combinatorial Pharmacogenetic Interactions of Bucindolol and β1, α2C Adrenergic Receptor Polymorphisms","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; ARCA Biopharma; U.S. Department of Veterans Affairs","keywords":"Pharmacogenetics; Minor allele frequency; Allele; Genotype; Population; Pharmacology; Internal medicine; Pharmacodynamics; Allele frequency; Polymorphism (computer science); Pharmacokinetics; Endocrinology; Medicine; Biology; Genetics; Gene","score_opus":0.03125469693430898,"score_gpt":0.24496434657178534,"score_spread":0.21370964963747635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009657275","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967974,0.0018953006,0.00016604882,0.0000465393,0.00046858797,0.00013386917,0.000019166258,0.000009510872,0.00046356785],"genre_scores_gemma":[0.99677294,0.00036268396,0.0017077355,0.00007091303,0.0007578609,0.000022246759,0.000050927192,0.000021682281,0.00023298053],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992345,0.00005494827,0.00018839289,0.00017234232,0.00013797765,0.00021185062],"domain_scores_gemma":[0.9995448,0.000014882033,0.000091654285,0.00015866246,0.000065068874,0.00012492543],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012502327,0.00011830011,0.0001719054,0.000041630017,0.000054809847,0.000008952241,0.00008836467,0.00008484303,0.00048092182],"category_scores_gemma":[0.00003636739,0.00011716042,0.00005204369,0.000056125227,0.00004229739,0.0000067810465,0.00007482385,0.000077932615,0.000012172328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007347599,0.0005589869,0.0017308842,0.0000219151,0.0001664318,1.4564016e-7,0.00007338928,0.0000019825186,0.9965355,0.0002539101,0.00015430622,0.0004290975],"study_design_scores_gemma":[0.0006416984,0.00019768668,0.00013958341,0.0000338659,0.000091698144,0.0000031025745,0.00003930653,0.000029382229,0.9974164,0.00006176775,0.0012115994,0.00013390946],"about_ca_topic_score_codex":0.0000119356055,"about_ca_topic_score_gemma":9.853574e-7,"teacher_disagreement_score":0.0015913008,"about_ca_system_score_codex":0.000007825118,"about_ca_system_score_gemma":0.000020495767,"threshold_uncertainty_score":0.5265757},"labels":[],"label_agreement":null},{"id":"W2009659713","doi":"10.1016/j.ejphar.2006.05.009","title":"Receptors involved in moxonidine-stimulated atrial natriuretic peptide release from isolated normotensive rat hearts","year":2006,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôtel-Dieu de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Moxonidine; Imidazoline receptor; Atrial natriuretic peptide; Prazosin; Chemistry; Endocrinology; Internal medicine; Agonist; Brimonidine; Yohimbine; Sympatholytic; Alpha-2 adrenergic receptor; Pharmacology; Receptor; Medicine; Antagonist","score_opus":0.00956171608431502,"score_gpt":0.2400125798972089,"score_spread":0.23045086381289387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009659713","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931284,0.0020245938,0.0016652511,0.00037715738,0.002455247,0.00017231585,0.000008601621,0.0000113758815,0.00015702852],"genre_scores_gemma":[0.9951674,0.00031389628,0.0011734182,0.00051205227,0.0025188408,6.2144807e-7,0.000072313305,0.000055794982,0.00018571694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99730927,0.0009965986,0.00086002355,0.00030847784,0.00017414714,0.00035146935],"domain_scores_gemma":[0.99888307,0.000057771947,0.00048650146,0.00012662541,0.0003080397,0.00013797035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070858287,0.00024473594,0.0003743687,0.00018211424,0.00006912197,0.000026019428,0.00028059154,0.00011717909,0.0005768806],"category_scores_gemma":[0.000111447436,0.0002278827,0.0002737084,0.00018436532,0.00006881205,0.0000130460285,0.00009107629,0.00043568385,0.00003691976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001588341,0.00007719119,0.00038833453,0.000004186717,0.00010765528,0.00068807637,0.000059734964,0.012452489,0.9616319,0.000003170756,0.022583928,0.00041497764],"study_design_scores_gemma":[0.010494191,0.0020687412,0.0006698827,0.000063814936,0.00020661185,0.0001321115,0.00010153326,0.0023496514,0.93150675,0.00010910862,0.05181102,0.00048655554],"about_ca_topic_score_codex":0.000056353892,"about_ca_topic_score_gemma":0.000013338386,"teacher_disagreement_score":0.030125137,"about_ca_system_score_codex":0.00004576004,"about_ca_system_score_gemma":0.00011113115,"threshold_uncertainty_score":0.9292787},"labels":[],"label_agreement":null},{"id":"W2009935784","doi":"10.1074/jbc.m110.182881","title":"CK2 Phosphorylation of an Acidic Ser/Thr Di-isoleucine Motif in the Na+/H+ Exchanger NHE5 Isoform Promotes Association with β-Arrestin2 and Endocytosis","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Hospital for Sick Children; McGill University","funders":"U.S. Public Health Service","keywords":"Internalization; Phosphorylation; G protein-coupled receptor; Endocytic cycle; Biochemistry; Threonine; Kinase; Serine; Cell biology; Endocytosis; Protein subunit; Isoleucine; Casein kinase 2; Chemistry; Signal transducing adaptor protein; Biology; Protein kinase A; Amino acid; Receptor; Leucine; Cyclin-dependent kinase 2; Gene","score_opus":0.023446495467016805,"score_gpt":0.22947583668446997,"score_spread":0.20602934121745317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009935784","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986592,0.0006259583,0.00036373493,0.0000472844,0.000026094567,0.0000773619,0.000005357804,0.0000026238931,0.00019241632],"genre_scores_gemma":[0.9986355,0.00025814548,0.0008808066,0.000037952537,0.00013662483,0.000004640246,0.000018192093,0.000006798295,0.000021358212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991551,0.00006047038,0.00031512877,0.00015398685,0.0001605859,0.00015474639],"domain_scores_gemma":[0.99922895,0.000030474039,0.00044352975,0.00011366256,0.00012694784,0.000056408844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061474653,0.00012340423,0.00020335168,0.000017609806,0.000037239042,0.000013122246,0.00016431765,0.00021757362,0.00007144396],"category_scores_gemma":[0.00016636153,0.00006894518,0.000060844483,0.00007510409,0.00006160659,0.000011952969,0.000032141947,0.00017629549,1.914732e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022716237,0.00012395128,0.05099417,0.00002093154,0.000031593027,0.000007091035,0.00020864555,0.0000052800387,0.94713646,0.0000035888663,0.000010271448,0.0012308529],"study_design_scores_gemma":[0.00051530305,0.0009899616,0.027090976,0.00003788968,0.00001968054,0.00007364655,0.00043998798,0.00003949652,0.9705156,0.00011868108,0.000063765874,0.000094978794],"about_ca_topic_score_codex":0.00001253489,"about_ca_topic_score_gemma":0.0000034566187,"teacher_disagreement_score":0.023903191,"about_ca_system_score_codex":0.00002117336,"about_ca_system_score_gemma":0.000028970655,"threshold_uncertainty_score":0.28115028},"labels":[],"label_agreement":null},{"id":"W2010140924","doi":"10.1016/j.jmb.2012.01.008","title":"Catalytic Activity and Acyl-Chain Selectivity of Diacylglycerol Kinase ɛ Are Modulated by Residues in and near the Lipoxygenase-Like Motif","year":2012,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Diacylglycerol kinase; Biochemistry; Phosphatidic acid; Phosphorylation; Chemistry; Mutant; Gene isoform; Amino acid; Enzyme; Peptide sequence; Protein kinase C; Biology; Gene; Phospholipid","score_opus":0.006429979947964304,"score_gpt":0.24037159630786092,"score_spread":0.23394161635989663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010140924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896697,0.0072294045,0.0026492116,0.00019976654,0.00010249271,0.0001247705,0.000014837884,0.000001940806,0.000007873157],"genre_scores_gemma":[0.9991027,0.00038592858,0.00030376716,0.000104572464,0.000065887645,0.0000029804817,0.0000077920995,0.000016560136,0.000009796219],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882007,0.0003444622,0.00028533125,0.00018697434,0.000095882344,0.00026727415],"domain_scores_gemma":[0.9992187,0.000045309705,0.0003551841,0.0001829179,0.00008823061,0.00010962598],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00076186843,0.00016286774,0.00031595136,0.00006202499,0.00006989425,0.000018638451,0.00013205604,0.00021552313,0.0000037133834],"category_scores_gemma":[0.00018508377,0.000116906565,0.000082022474,0.00009994337,0.00019168535,0.0000118605285,0.00010867917,0.00021278557,2.0856125e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001777272,0.000093496885,0.014136873,0.00001667404,0.00008314462,0.0000061570495,0.00012995409,0.00004957921,0.9828128,0.000015928275,0.00006742935,0.0024102028],"study_design_scores_gemma":[0.0006864364,0.0004983439,0.019789888,0.000023879353,0.000030902316,0.00009983902,0.0000820981,0.00017759956,0.9779268,0.00016865993,0.0003799027,0.0001356355],"about_ca_topic_score_codex":0.00011323317,"about_ca_topic_score_gemma":0.00003377911,"teacher_disagreement_score":0.009433012,"about_ca_system_score_codex":0.000015040811,"about_ca_system_score_gemma":0.000054050262,"threshold_uncertainty_score":0.47673112},"labels":[],"label_agreement":null},{"id":"W2010296719","doi":"10.1002/jnr.22401","title":"Interaction of dopamine D1 receptor with N‐ethylmaleimide‐sensitive factor is important for the membrane localization of the receptor","year":2010,"lang":"en","type":"article","venue":"Journal of Neuroscience Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Science Foundation","keywords":"Dopamine receptor D1; Cell biology; Dopamine; Receptor; Dendritic spine; Chemistry; Neuroscience; Dopamine receptor; Biology; Hippocampal formation; Biochemistry","score_opus":0.045021958398184354,"score_gpt":0.3460147450701846,"score_spread":0.30099278667200025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010296719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9840651,0.00004637683,0.014237513,0.0006070541,0.0007250052,0.00028288798,0.000022091972,9.576468e-7,0.000012985644],"genre_scores_gemma":[0.9986671,0.00033831273,0.0005135117,0.00007098192,0.0001902713,0.000004405274,0.000001239477,0.000012544007,0.00020163658],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845386,0.00013878365,0.0003878623,0.00017366468,0.00064606185,0.00019975178],"domain_scores_gemma":[0.997865,0.00017233039,0.00048343264,0.0002476424,0.0011670797,0.0000645227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014307081,0.00008522736,0.00014636818,0.000088605746,0.00017702757,0.000030737418,0.00041522208,0.00007090122,0.000040461993],"category_scores_gemma":[0.001135684,0.000042505533,0.000116860814,0.00034170225,0.00036619016,0.000021096357,0.00008081229,0.00035105122,2.480041e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032266337,0.000049603783,0.000560839,0.000019791612,0.000010375664,3.6573192e-7,0.00013985869,0.00012354535,0.99702424,0.000021525542,0.00019742422,0.0015297841],"study_design_scores_gemma":[0.0002491572,0.0010876968,0.0005600083,0.000049024293,0.000007737894,0.000033633845,0.00037567315,0.0010414824,0.98840797,0.000011750706,0.008128165,0.00004772901],"about_ca_topic_score_codex":0.00002163901,"about_ca_topic_score_gemma":0.000016596554,"teacher_disagreement_score":0.014601969,"about_ca_system_score_codex":0.0000126980885,"about_ca_system_score_gemma":0.00024188828,"threshold_uncertainty_score":0.17333253},"labels":[],"label_agreement":null},{"id":"W2010450338","doi":"10.1523/jneurosci.4757-04.2005","title":"Pathological Aggression in “Fierce” Mice Corrected by Human Nuclear Receptor 2E1","year":2005,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Children's & Women's Health Centre of British Columbia","funders":"British Columbia Knowledge Development Fund; Canadian Institutes of Health Research; Scottish Rite Charitable Foundation of Canada","keywords":"Gene knockin; Transgene; Genetically modified mouse; Biology; Gene; Aggression; Locus (genetics); Genetics; Pathological; Mutant; clone (Java method); Neuroscience; Psychology; Pathology; Medicine; Developmental psychology","score_opus":0.013488530590732874,"score_gpt":0.26509648991968576,"score_spread":0.2516079593289529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010450338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99859583,0.0002804949,0.0004042426,0.00021781253,0.0003727389,0.000040735635,0.0000025852453,0.0000038176413,0.00008176787],"genre_scores_gemma":[0.99745226,0.0003820299,0.000993616,0.00079380494,0.0001883344,5.2126563e-7,0.0000016424036,0.0000095668875,0.00017822292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901223,0.00009379489,0.00030045962,0.0002007033,0.00020505532,0.00018778126],"domain_scores_gemma":[0.99950635,0.00000828615,0.00023038432,0.0000991572,0.000059596892,0.000096239375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003337803,0.000092665745,0.0001306277,0.000054227086,0.00008746499,0.00003398725,0.00031351327,0.000094648916,0.00006761774],"category_scores_gemma":[0.0001916149,0.00007209584,0.00006695389,0.00012339793,0.000065453794,0.000014162222,0.00006881656,0.00020514448,0.000004019604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003665479,0.000082348575,0.00023432139,0.000001239157,5.248821e-7,0.000012173481,0.0000420178,0.00006219809,0.99303883,0.0000056007293,0.0034990082,0.0029850833],"study_design_scores_gemma":[0.0006196086,0.0012372993,0.002322975,0.0000869653,0.000004226894,0.00023505851,0.000078966266,0.0003405182,0.90855217,0.000023246019,0.08631363,0.00018535342],"about_ca_topic_score_codex":0.0000016905113,"about_ca_topic_score_gemma":0.0000014251885,"teacher_disagreement_score":0.08448668,"about_ca_system_score_codex":0.000016513639,"about_ca_system_score_gemma":0.000025152767,"threshold_uncertainty_score":0.2939983},"labels":[],"label_agreement":null},{"id":"W2010738219","doi":"10.1371/journal.pone.0041354","title":"Differential Regulation of Transcription Factors by Location-Specific EGF Receptor Signaling via a Spatio-Temporal Interplay of ERK Activation","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Internalization; MAPK/ERK pathway; Cell biology; Endocytosis; Endosome; Chinese hamster ovary cell; Epidermal growth factor receptor; Signal transduction; Cell growth; Cell; Chemistry; Transcription factor; Biology; Phosphorylation; Cell culture; Receptor; Intracellular; Biochemistry; Genetics; Gene","score_opus":0.02278670358087217,"score_gpt":0.22038316070962782,"score_spread":0.19759645712875565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010738219","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8744652,0.0001688019,0.12503688,0.000012491683,0.00009138914,0.00018094336,0.000020203972,0.000007954153,0.000016082038],"genre_scores_gemma":[0.99622524,0.000036140216,0.0019888277,0.000005396874,0.00018792255,0.000011751528,0.0014506903,0.000020964315,0.00007306025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990507,0.00006399352,0.00034228794,0.00016693326,0.00023283307,0.00014328705],"domain_scores_gemma":[0.9993559,0.000012987305,0.00025382283,0.00015327444,0.00017268176,0.00005133868],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011376474,0.0001238804,0.00018680589,0.000057397036,0.000040006697,0.000008178683,0.000079236816,0.00014556997,0.0004916835],"category_scores_gemma":[0.000021946096,0.00012211368,0.00006837022,0.00009396714,0.000030018728,0.000022552802,0.000013874593,0.000059250833,0.0000021202711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001476378,0.0005748722,0.0040786206,0.000077189055,0.00009711884,3.5198895e-9,0.00038455575,0.000023585902,0.99405426,0.00005794052,0.00008014222,0.0004240856],"study_design_scores_gemma":[0.00027058375,0.0001956217,0.0011867635,0.00010854278,0.000034146702,8.182237e-8,0.00009586337,0.0001890125,0.9976354,0.000029552415,0.00013401815,0.00012038219],"about_ca_topic_score_codex":0.000026874084,"about_ca_topic_score_gemma":0.0000021683531,"teacher_disagreement_score":0.12304805,"about_ca_system_score_codex":0.000022221799,"about_ca_system_score_gemma":0.000014231999,"threshold_uncertainty_score":0.538359},"labels":[],"label_agreement":null},{"id":"W2010782393","doi":"10.1074/jbc.m804671200","title":"The Third Intracellular Loop Stabilizes the Inactive State of the Neuropeptide Y1 Receptor","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Alberta","funders":"Canadian Institutes of Health Research; Sächsisches Staatsministerium für Wissenschaft und Kunst; Deutsche Forschungsgemeinschaft","keywords":"Receptor; G protein-coupled receptor; G protein; Agonist; Cell biology; Biology; Biophysics; Signal transduction; Transmembrane domain; Chemistry; Biochemistry","score_opus":0.01662270605433485,"score_gpt":0.22095712766379758,"score_spread":0.20433442160946272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010782393","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967293,0.0020203043,0.00015154842,0.00046181862,0.00020470444,0.000094159805,0.000009884302,0.000002939754,0.0003253402],"genre_scores_gemma":[0.99617577,0.0026608815,0.0001153099,0.00012270737,0.0003130153,0.00000317118,0.0000028495795,0.000010373288,0.0005959219],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870384,0.00019274784,0.00048479615,0.00016638843,0.00023344756,0.00021881204],"domain_scores_gemma":[0.99863386,0.00014049455,0.0005723945,0.0003264593,0.00025814614,0.00006862735],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006319848,0.00015812808,0.00021103803,0.00000558624,0.0002812862,0.000019404599,0.0007169254,0.00013031416,0.00006146285],"category_scores_gemma":[0.000635874,0.00006112875,0.00029662094,0.00009563086,0.0004951064,0.0000046441405,0.00018775268,0.00042371085,0.0000016716632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021178901,0.00004760094,0.0005142819,0.0000061798837,0.00006118704,0.0000044848166,0.00005446122,0.000082476196,0.9972546,0.000006926834,0.0009386879,0.00081732473],"study_design_scores_gemma":[0.00021848721,0.00024761577,0.0005190048,0.000016393778,0.000011466031,0.00011973384,0.00027388902,0.000009099634,0.9776565,0.00015272267,0.020687342,0.00008777337],"about_ca_topic_score_codex":0.0000026326502,"about_ca_topic_score_gemma":6.343385e-7,"teacher_disagreement_score":0.019748654,"about_ca_system_score_codex":0.000019210354,"about_ca_system_score_gemma":0.00010727635,"threshold_uncertainty_score":0.24927579},"labels":[],"label_agreement":null},{"id":"W2010982041","doi":"10.1155/2011/356137","title":"New Considerations for Spectral Classification of Boolean Switching Functions","year":2011,"lang":"en","type":"article","venue":"VLSI design","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; University of Lethbridge","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Boolean function; Computer science; Algorithm; Theoretical computer science; Data mining","score_opus":0.09276390712383112,"score_gpt":0.26126488100447043,"score_spread":0.1685009738806393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010982041","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.038946047,0.000063224,0.959642,0.000038354618,0.00015632036,0.00022470231,0.000005465587,0.000010844647,0.0009130201],"genre_scores_gemma":[0.8529257,0.000008406325,0.14628386,0.000036733498,0.00015449028,0.000018425399,0.000017048853,0.000012156094,0.00054317433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994967,0.000030103,0.00015863289,0.00015966345,0.00004641938,0.00010845521],"domain_scores_gemma":[0.999644,0.000025087274,0.000070785965,0.00015228213,0.000059761238,0.00004810946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000162391,0.000070781156,0.00007641219,0.000032069875,0.00008233502,0.00001066126,0.0000504676,0.000070101836,0.00020575267],"category_scores_gemma":[0.000074757816,0.000069068505,0.00006809127,0.000033027118,0.000010734911,0.000004068805,0.000008609544,0.00003182481,0.00000500563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030238007,0.000021016833,0.00004852829,0.0000037979878,0.00002566365,1.2917609e-7,0.00011928697,0.000051706334,0.9883043,0.006093401,0.0034406474,0.0018612971],"study_design_scores_gemma":[0.00027148495,0.00030957864,0.00028257977,0.0000057066127,0.00002646015,0.0000041000803,0.00015833467,0.0004622248,0.99129325,0.006036896,0.0010560355,0.000093368995],"about_ca_topic_score_codex":0.000020433969,"about_ca_topic_score_gemma":0.0000104183155,"teacher_disagreement_score":0.8139796,"about_ca_system_score_codex":0.0000051797538,"about_ca_system_score_gemma":0.00009262761,"threshold_uncertainty_score":0.2816532},"labels":[],"label_agreement":null},{"id":"W2010992068","doi":"10.1021/jp909971f","title":"Molecular Dynamics Simulations Reveal Fundamental Role of Water As Factor Determining Affinity of Binding of β-Blocker Nebivolol to β<sub>2</sub>-Adrenergic Receptor","year":2010,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"China Scholarship Council","keywords":"Nebivolol; BETA (programming language); Chemistry; Adrenergic receptor; Binding site; Receptor; Stereochemistry; Biophysics; Biochemistry; Biology; Endocrinology","score_opus":0.005259478784089711,"score_gpt":0.23189942289572096,"score_spread":0.22663994411163124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010992068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9994982,0.000020050691,0.00020852045,0.000021907452,0.00006124395,0.000070061986,0.00006088084,0.000002046713,0.000057076668],"genre_scores_gemma":[0.99938476,0.0000042021597,0.0003328445,0.00001101404,0.000203365,0.0000010652597,0.000025866257,0.000021545351,0.00001532221],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998909,0.00004404254,0.0004560871,0.00012959767,0.00027263755,0.00018866737],"domain_scores_gemma":[0.9989636,0.00004666,0.00040604617,0.0002469088,0.00022537934,0.00011142156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018651287,0.00016049296,0.00031540086,0.000029742669,0.000047415375,0.000007757769,0.0003177537,0.00012363626,0.00005269157],"category_scores_gemma":[0.00009077779,0.000111358095,0.00023874667,0.00007820555,0.00009226877,0.000008613392,0.00013174901,0.00025401713,0.0000013511301],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017808059,0.00012950125,0.00018679583,0.000036048656,0.00008749223,7.91535e-7,0.00032226878,0.0020641226,0.99644244,0.000009735875,0.000003674779,0.0005390754],"study_design_scores_gemma":[0.00030619305,0.00037860608,0.00004313481,0.000046444187,0.000060010356,0.0000145492595,0.00024752718,0.00092987466,0.9977117,0.00011536904,0.000025655523,0.00012089524],"about_ca_topic_score_codex":0.0000054782904,"about_ca_topic_score_gemma":0.0000017391859,"teacher_disagreement_score":0.0012693283,"about_ca_system_score_codex":0.000021090344,"about_ca_system_score_gemma":0.000081425016,"threshold_uncertainty_score":0.45410514},"labels":[],"label_agreement":null},{"id":"W2011287700","doi":"10.1371/journal.pone.0067608","title":"MOR Is Not Enough: Identification of Novel mu-Opioid Receptor Interacting Proteins Using Traditional and Modified Membrane Yeast Two-Hybrid Screens","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Pennsylvania State University; University of Pennsylvania; National Institute on Drug Abuse; Penn State College of Medicine; Pennsylvania Department of Health; Heart and Stroke Foundation of Canada","keywords":"μ-opioid receptor; Opioid; Opioid receptor; Receptor; Agonist; DAMGO; G protein-coupled receptor; HEK 293 cells; Cell biology; Pharmacology; δ-opioid receptor; Chemistry; Signal transduction; Biology; Neuroscience; Biochemistry","score_opus":0.07685732176008357,"score_gpt":0.2473048464644789,"score_spread":0.17044752470439534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011287700","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98664427,0.00005570395,0.012462807,0.00011074491,0.000055566663,0.0004303238,0.00015465947,0.000009127683,0.00007679181],"genre_scores_gemma":[0.97927254,0.00003038946,0.019949792,0.000082070066,0.00025522753,0.00004419313,0.00017474606,0.000024177538,0.00016688816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899167,0.000027294243,0.0003170531,0.000296606,0.00020938455,0.00015801608],"domain_scores_gemma":[0.9993522,0.000014475053,0.00020491195,0.00018468377,0.00017658206,0.00006711253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014637136,0.000128751,0.00017649795,0.000048589234,0.00008358959,0.00004496739,0.00010110243,0.00006489407,0.0002431415],"category_scores_gemma":[0.00007989958,0.00013337696,0.000053406777,0.00004735941,0.000042689368,0.000020731593,0.00003781507,0.00008860354,0.0000069510606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039160084,0.00042752112,0.00003158031,0.00007563563,0.00011513741,1.5304771e-7,0.00010007842,0.000061668776,0.99877316,0.00009291173,0.000019523612,0.00026345375],"study_design_scores_gemma":[0.00050335017,0.00009406229,0.00009174755,0.00011187246,0.000040946838,0.0000046311193,0.0000717727,0.015762089,0.9831242,0.000032671727,0.000017999319,0.00014467092],"about_ca_topic_score_codex":0.00012947126,"about_ca_topic_score_gemma":0.000002290406,"teacher_disagreement_score":0.01570042,"about_ca_system_score_codex":0.000013404751,"about_ca_system_score_gemma":0.00003201944,"threshold_uncertainty_score":0.5438955},"labels":[],"label_agreement":null},{"id":"W2011324850","doi":"10.1038/sj.tpj.6500309","title":"Distinct proteomic profiles of amphetamine self-administration transitional states","year":2005,"lang":"en","type":"article","venue":"The Pharmacogenomics Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute on Drug Abuse; Wake Forest School of Medicine; National Institutes of Health; Wake Forest University","keywords":"Amphetamine; Abstinence; Self-administration; Nucleus accumbens; Hippocampus; Neuroscience; Psychology; Addiction; Pharmacology; Medicine; Dopamine; Psychiatry","score_opus":0.009455035968104946,"score_gpt":0.25624451627512296,"score_spread":0.246789480307018,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011324850","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98819244,0.0003492645,0.010417091,0.00060264295,0.00010855013,0.00018525847,0.000043664764,0.0000058000437,0.00009527443],"genre_scores_gemma":[0.9945261,0.00043891987,0.0037519068,0.00011440442,0.000988029,0.000009751016,0.00006490892,0.000016723478,0.00008929125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992269,0.00007391177,0.00029615956,0.000116265706,0.00012873336,0.00015800013],"domain_scores_gemma":[0.99955565,0.000009318451,0.00018388053,0.00009148766,0.000093223956,0.00006642134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042987915,0.000111839334,0.00010114284,0.00002423133,0.00016857541,0.000030677595,0.00018695211,0.00004092231,0.0002270733],"category_scores_gemma":[0.000006387995,0.00008082172,0.000106875465,0.000033105225,0.000045468598,0.000007133875,0.000021948501,0.00012916821,0.0000061379387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017785729,0.000085092084,0.00009798487,0.0000084008425,0.00008125717,0.0000014329445,0.00012671901,0.000830891,0.99537575,0.000061080325,0.00026955284,0.002884001],"study_design_scores_gemma":[0.0006084716,0.0001652824,0.00015139217,0.0000066953803,0.000053016338,0.0002543478,0.00004617142,0.002183535,0.98877275,0.00025383726,0.0073943543,0.000110120076],"about_ca_topic_score_codex":9.544559e-7,"about_ca_topic_score_gemma":0.0000019094816,"teacher_disagreement_score":0.0071248016,"about_ca_system_score_codex":0.000024641242,"about_ca_system_score_gemma":0.00012381504,"threshold_uncertainty_score":0.32958144},"labels":[],"label_agreement":null},{"id":"W2011421397","doi":"10.1371/journal.pone.0077027","title":"Reactive Oxygen Species Are Required for 5-HT-Induced Transactivation of Neuronal Platelet-Derived Growth Factor and TrkB Receptors, but Not for ERK1/2 Activation","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"University of Waterloo","keywords":"Transactivation; Platelet-derived growth factor receptor; Phosphorylation; Cell biology; Tropomyosin receptor kinase B; NADPH oxidase; Receptor tyrosine kinase; Biology; Apocynin; Tyrosine phosphorylation; Signal transduction; Receptor; Reactive oxygen species; Chemistry; Biochemistry; Growth factor; Transcription factor; Neurotrophic factors","score_opus":0.05159574571061893,"score_gpt":0.22282401516052713,"score_spread":0.1712282694499082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011421397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870192,0.00001562009,0.011254633,0.0003203588,0.00005537797,0.0011702529,0.00013082814,0.000013653102,0.000020121122],"genre_scores_gemma":[0.9941597,0.00004094732,0.0047223214,0.00008350288,0.000211142,0.00024697042,0.00030082455,0.000036590533,0.00019799905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902165,0.000032255364,0.00025170378,0.0003387474,0.00015735821,0.00019825844],"domain_scores_gemma":[0.9991446,0.00007649867,0.00023728653,0.00013299723,0.00034654964,0.000062068466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007932383,0.00016940181,0.00026152984,0.000051562933,0.00009695075,0.000027016991,0.000087805645,0.00018652408,0.00005670473],"category_scores_gemma":[0.00021219318,0.00016459974,0.00008278695,0.000045345252,0.000028538621,0.00003203436,0.00001559252,0.00006378774,6.5959733e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004742623,0.00015880917,0.000055018692,0.000114848954,0.0001831087,3.470211e-8,0.00014768858,0.0000010706459,0.99769723,0.000052099596,0.000055176966,0.0010606366],"study_design_scores_gemma":[0.0010159169,0.0007214937,0.0029914493,0.000056391313,0.00003580305,2.8955517e-7,0.00022927536,0.00016035361,0.99427384,0.0002468751,0.00008287296,0.00018545074],"about_ca_topic_score_codex":0.000024802996,"about_ca_topic_score_gemma":0.0000032237474,"teacher_disagreement_score":0.007140547,"about_ca_system_score_codex":0.000021343627,"about_ca_system_score_gemma":0.00003321612,"threshold_uncertainty_score":0.6712183},"labels":[],"label_agreement":null},{"id":"W2011958502","doi":"10.1081/rrs-200035217","title":"Chimeric G Proteins Extend the Range of Insect Cell-Based Functional Assays for Human G Protein-Coupled Receptors","year":2004,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Killam Trusts","keywords":"G protein-coupled receptor; G protein; Sf9; Receptor; Biology; Gq alpha subunit; Cell biology; Gs alpha subunit; Fusion protein; Aequorin; Agonist; Rhodopsin-like receptors; Signal transduction; Biochemistry; Intracellular; Metabotropic receptor; Recombinant DNA; Spodoptera","score_opus":0.017073946622472743,"score_gpt":0.22873971908688012,"score_spread":0.21166577246440738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011958502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8078587,0.0007809916,0.19005194,0.00020172344,0.0004915046,0.0005790524,0.000008500531,0.0000048936013,0.000022688708],"genre_scores_gemma":[0.9949232,0.000103632585,0.0039790175,0.00003485387,0.0007450215,0.000046004392,0.000024425384,0.000030450377,0.00011342679],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986229,0.000095595475,0.0005454761,0.00022445247,0.00030889062,0.00020269968],"domain_scores_gemma":[0.9989806,0.000020179386,0.00048180643,0.0001183379,0.00030636415,0.000092704555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080370146,0.00020404927,0.00028665006,0.00011247561,0.0002498078,0.00002997786,0.00013759773,0.00016739042,0.00023716183],"category_scores_gemma":[0.00002663646,0.00014313895,0.00033373717,0.0001405986,0.00011590347,0.000021021193,0.0000086414775,0.00020410778,3.5218656e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006092824,0.00016933115,0.000074992284,0.000076536686,0.00007753971,4.959995e-7,0.000112167414,0.002673133,0.99413013,0.00011658275,0.00008454296,0.0018752828],"study_design_scores_gemma":[0.0026158849,0.0028097446,0.00018515755,0.00008868029,0.000084187275,0.000028408074,0.00022809772,0.000058982336,0.99013644,0.000796125,0.0027814717,0.00018681477],"about_ca_topic_score_codex":0.000024337322,"about_ca_topic_score_gemma":0.0000073471324,"teacher_disagreement_score":0.18706447,"about_ca_system_score_codex":0.00003129893,"about_ca_system_score_gemma":0.00016224527,"threshold_uncertainty_score":0.58370376},"labels":[],"label_agreement":null},{"id":"W2011964198","doi":"10.1089/adt.2007.062","title":"Emerging Concepts of Guanine Nucleotide-Binding Protein-Coupled Receptor (GPCR) Function and Implications for High Throughput Screening","year":2007,"lang":"en","type":"review","venue":"Assay and Drug Development Technologies","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"PerkinElmer Biosignal","funders":"","keywords":"G protein-coupled receptor; Guanine; Function (biology); Computational biology; Throughput; Nucleotide; Biology; Receptor; Chemistry; Genetics; Computer science; Gene","score_opus":0.03043812253801149,"score_gpt":0.30858742315241827,"score_spread":0.2781493006144068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011964198","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010955215,0.9156648,0.071278356,0.00011048936,0.00015433195,0.0015867394,0.00004317332,0.00016599997,0.000040891424],"genre_scores_gemma":[0.0142274415,0.9054596,0.0786969,0.000010567982,0.00006779123,0.0005031117,0.0006134494,0.000064880245,0.00035627143],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982563,0.000034919423,0.00064663147,0.0006213492,0.00010895348,0.00033183835],"domain_scores_gemma":[0.9989956,0.00008208135,0.0004896364,0.0002752054,0.000120078075,0.000037383787],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007543482,0.00038873468,0.00073848123,0.00020381832,0.00029964725,0.000038825354,0.00022281281,0.00051551475,0.000008858935],"category_scores_gemma":[0.00021220246,0.0003338451,0.00011444485,0.00020841742,0.00013540468,0.000012601067,0.00030582972,0.00018860669,0.0000010723492],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001703903,0.000018025015,0.000025217649,0.0015606269,0.00021607698,1.9089077e-7,0.00002823944,4.491875e-7,0.043362115,0.0029489072,0.00015770795,0.9516654],"study_design_scores_gemma":[0.0005032186,0.00016773975,0.000014082607,0.003148431,0.00020715923,0.000008217027,0.00072813564,0.000003882968,0.1047299,0.0008420102,0.88893116,0.00071607437],"about_ca_topic_score_codex":0.000005027949,"about_ca_topic_score_gemma":0.0000050038566,"teacher_disagreement_score":0.9509493,"about_ca_system_score_codex":0.000026739073,"about_ca_system_score_gemma":0.00011174951,"threshold_uncertainty_score":0.99991137},"labels":[],"label_agreement":null},{"id":"W2011982625","doi":"10.1371/journal.pone.0087709","title":"Distribution of VGLUT3 in Highly Collateralized Axons from the Rat Dorsal Raphe Nucleus as Revealed by Single-Neuron Reconstructions","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Dorsal raphe nucleus; Biotinylated dextran amine; Neuroscience; Axon; Serotonergic cell groups; Raphe nuclei; Anatomy; Nucleus; Biology; Chemistry; Serotonergic; Serotonin","score_opus":0.015422182722739054,"score_gpt":0.19817819579327323,"score_spread":0.18275601307053418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011982625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981441,0.0001876261,0.0005889057,0.00034758713,0.000119233635,0.00020838206,0.00018113849,0.000011329836,0.00021173368],"genre_scores_gemma":[0.99807304,0.000108493645,0.00083832024,0.000113434384,0.00009931243,0.000018492134,0.00055768224,0.000015444472,0.00017574943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902743,0.00017586915,0.00026336196,0.00024115972,0.00013046831,0.00016168272],"domain_scores_gemma":[0.99946237,0.000048179314,0.00011782183,0.00026855065,0.000064203516,0.0000388897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015586302,0.00011367467,0.00019406389,0.000015766891,0.00007694945,0.000023104843,0.00014491742,0.00012368645,0.00010580465],"category_scores_gemma":[0.00016279306,0.000093974515,0.000063574545,0.00009827859,0.00006469226,0.0000046914015,0.00004615704,0.000091184535,0.0000070492747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009529224,0.00022357529,0.0014225967,0.0000066228054,0.00005569635,3.009732e-7,0.000029216404,0.0000061878723,0.99690783,0.00011389858,0.00074175955,0.00039702136],"study_design_scores_gemma":[0.00082567945,0.00027109467,0.00064061006,0.00006567146,0.000052743864,0.0000016112039,0.000040294846,0.00014270496,0.9938833,0.0004677276,0.003483002,0.00012557731],"about_ca_topic_score_codex":0.00020682276,"about_ca_topic_score_gemma":0.0000519259,"teacher_disagreement_score":0.0030245495,"about_ca_system_score_codex":0.000015967384,"about_ca_system_score_gemma":0.000022760501,"threshold_uncertainty_score":0.38321695},"labels":[],"label_agreement":null},{"id":"W2012175267","doi":"10.1016/s0895-7061(03)00330-3","title":"Cardiovascular effects of human ?new pressor protein? (NPP) and coagulation $beta;-FXIIa: its potentiation by the ace inhibitor captopril and by 24hr nephrectomy","year":2003,"lang":"en","type":"article","venue":"American Journal of Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Heart and Stroke Foundation; University of Toronto","funders":"","keywords":"Captopril; Internal medicine; Medicine; Endocrinology; Nephrectomy; Long-term potentiation; Blood pressure; ACE inhibitor; Bradykinin; Kidney; Pharmacology; Angiotensin-converting enzyme; Receptor","score_opus":0.006075014127746434,"score_gpt":0.1952205337462904,"score_spread":0.18914551961854395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012175267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9803525,0.01623191,0.0029680629,0.00013624734,0.00007325809,0.00022629026,0.0000016809445,0.0000022388203,0.0000077651175],"genre_scores_gemma":[0.99865323,0.00052998157,0.000559519,0.00008947424,0.00008318898,0.0000028626341,0.000006946739,0.00001663792,0.000058184854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902314,0.00020131358,0.0002510189,0.00017123952,0.0002273061,0.00012598865],"domain_scores_gemma":[0.9992756,0.000020090847,0.00032094275,0.00013262594,0.0001641867,0.00008653137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032179093,0.00012789966,0.0002986212,0.000031840944,0.00009884356,0.000021122247,0.00006457971,0.00006481255,0.0000029274643],"category_scores_gemma":[0.000084801635,0.000089188055,0.0001129349,0.00006904987,0.000075582386,0.000016864684,0.000026542257,0.00009972216,1.5521938e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003920474,0.000024829202,0.00011846924,0.000019845136,0.0001579793,0.0000025641862,0.000049983682,0.000022414572,0.9923452,0.00001568241,0.0008696582,0.0063341693],"study_design_scores_gemma":[0.0008907772,0.0008835264,0.0003411691,0.00005960056,0.00015260304,0.0001251458,0.00010666333,0.00002469021,0.9922253,0.000037208236,0.0050418735,0.000111433976],"about_ca_topic_score_codex":0.00004904794,"about_ca_topic_score_gemma":0.0000010122103,"teacher_disagreement_score":0.018300656,"about_ca_system_score_codex":0.0000073500487,"about_ca_system_score_gemma":0.00003063484,"threshold_uncertainty_score":0.36369833},"labels":[],"label_agreement":null},{"id":"W2012295104","doi":"10.1016/j.bbr.2012.05.037","title":"Social defeat interacts with Disc1 mutations in the mouse to affect behavior","year":2012,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital; Centre for Addiction and Mental Health","funders":"","keywords":"Affect (linguistics); DISC1; Social defeat; Psychology; Neuroscience; Agonistic behaviour; Genetics; Biology; Developmental psychology; Communication; Gene; Aggression","score_opus":0.10722414407768818,"score_gpt":0.41510910369239507,"score_spread":0.30788495961470685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012295104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977471,0.000048388938,0.000126651,0.001225903,0.000033462005,0.0006041872,0.000014298817,0.0000066484304,0.00019335246],"genre_scores_gemma":[0.9979247,0.0000017674874,0.0002805491,0.00019891196,0.00018818327,0.000373056,0.0001349116,0.000023871255,0.0008740744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982926,0.00040318616,0.00012687413,0.00022073135,0.00039724068,0.00055936526],"domain_scores_gemma":[0.9994856,0.00007345215,0.000021439877,0.0002129283,0.00008764498,0.00011891417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012278501,0.00011581037,0.00009543881,0.00010535011,0.0002489504,0.00008486516,0.00030013244,0.000093064606,0.00007681],"category_scores_gemma":[0.00012441918,0.00007612502,0.000057304023,0.0002606535,0.000075191594,0.0000120232535,0.00011971764,0.0002896086,0.000029091369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010298692,0.00029662577,0.066487044,0.000005275492,0.000008800625,0.000013483032,0.0025133418,0.000004497387,0.924215,0.0003302168,0.0038098092,0.0022129042],"study_design_scores_gemma":[0.00089005596,0.0011439702,0.3287058,0.000023420143,0.000026552694,0.000056346973,0.005797595,0.0000043904806,0.6592173,0.000026137788,0.003709202,0.00039923913],"about_ca_topic_score_codex":0.00020110182,"about_ca_topic_score_gemma":0.00035427356,"teacher_disagreement_score":0.2649977,"about_ca_system_score_codex":0.0000356611,"about_ca_system_score_gemma":0.000043278233,"threshold_uncertainty_score":0.31042883},"labels":[],"label_agreement":null},{"id":"W2012378217","doi":"10.1124/mol.106.029900","title":"Evidence for Direct Regulation of Myocardial Na+/H+ Exchanger Isoform 1 Phosphorylation and Activity by 90-kDa Ribosomal S6 Kinase (RSK): Effects of the Novel and Specific RSK Inhibitor fmk on Responses to α1-Adrenergic Stimulation","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"National Institute of General Medical Sciences; Medical Center, University of Rochester; University of Alberta","keywords":"Ribosomal s6 kinase; MAPK/ERK pathway; Phosphorylation; Kinase; Extracellular; Protein kinase A; Stimulation; Cell biology; Biology; Molecular biology; Myocyte; Biochemistry; Chemistry; Endocrinology; Protein kinase B","score_opus":0.014271902319565863,"score_gpt":0.2697783123206749,"score_spread":0.255506410001109,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012378217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9747176,0.0015892399,0.022299135,0.00013085641,0.0003513426,0.0008470693,0.000042218548,0.0000066046755,0.0000159356],"genre_scores_gemma":[0.9988507,0.000083866864,0.00055843504,0.00012888577,0.00016938182,0.00007893727,0.000034569424,0.00002253263,0.00007271386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989152,0.00016072621,0.00021524301,0.0003691594,0.00015689223,0.00018277981],"domain_scores_gemma":[0.9993541,0.00015695472,0.00017847358,0.00015865857,0.0001020606,0.00004975217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002660551,0.00017181794,0.00021576644,0.00006695114,0.0000900999,0.0000115536395,0.00007960328,0.0001605836,0.000009299187],"category_scores_gemma":[0.00009457165,0.00015189225,0.000091379276,0.000110920075,0.00007894969,0.000014460763,0.000078733035,0.00005952803,2.1139793e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001630618,0.00009029207,0.00026885676,0.00006349812,0.00003768786,6.97902e-7,0.000027257252,0.0016353843,0.9930866,0.00007170204,0.00049194554,0.0025954624],"study_design_scores_gemma":[0.0013563336,0.00071247714,0.012462518,0.000051519204,0.00007221772,0.000002287097,0.0000033644703,0.0010902669,0.98320264,0.00004592996,0.000852349,0.0001480924],"about_ca_topic_score_codex":0.00003133041,"about_ca_topic_score_gemma":0.0000029126936,"teacher_disagreement_score":0.024133079,"about_ca_system_score_codex":0.00002913032,"about_ca_system_score_gemma":0.000032070806,"threshold_uncertainty_score":0.6193986},"labels":[],"label_agreement":null},{"id":"W2012584489","doi":"10.1371/journal.pone.0065767","title":"Inverse Agonist and Pharmacochaperone Properties of MK-0524 on the Prostanoid DP1 Receptor","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Agonist; Prostanoid; Chemistry; Inverse agonist; Receptor; Pharmacology; Internal medicine; Endocrinology; Medicine","score_opus":0.03871260309841963,"score_gpt":0.2004962577442515,"score_spread":0.1617836546458319,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012584489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976122,0.0007253856,0.000015209807,0.00068149035,0.00003327701,0.00042705503,0.000007458458,0.000008672021,0.0004892545],"genre_scores_gemma":[0.9968745,0.00050602626,0.00053222425,0.00041203128,0.000121851044,0.000079020334,0.0000102706545,0.000018671926,0.0014453692],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932015,0.000045456516,0.00014406808,0.00019339229,0.000151619,0.0001453199],"domain_scores_gemma":[0.99959695,0.000007236129,0.000064675754,0.00018603104,0.000092477836,0.000052632528],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011209719,0.000112542846,0.00012820418,0.00001601268,0.000085902335,0.000028321021,0.00011050887,0.00006477268,0.00039982385],"category_scores_gemma":[0.000052057425,0.000072879055,0.00003262789,0.000035516467,0.00010212615,0.000004576126,0.00006693297,0.00007703869,0.000038291248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053509604,0.0002213362,0.00007734472,0.00006294135,0.00009374463,1.2055078e-7,0.00011402911,9.674768e-7,0.99818116,0.00012671654,0.0007265381,0.00034159765],"study_design_scores_gemma":[0.00022809311,0.00029981005,0.000016319531,0.00008605907,0.00002415999,4.4381653e-7,0.00016638316,0.00011929216,0.99824196,0.00004682746,0.0006675245,0.00010313567],"about_ca_topic_score_codex":0.000024241232,"about_ca_topic_score_gemma":0.0000023646635,"teacher_disagreement_score":0.0009561148,"about_ca_system_score_codex":0.00000602159,"about_ca_system_score_gemma":0.000022374601,"threshold_uncertainty_score":0.43777907},"labels":[],"label_agreement":null},{"id":"W2012602467","doi":"10.1016/s0006-8993(00)02591-9","title":"Neuronal Fos-like immunoreactivity in ouabain-induced hypertension","year":2000,"lang":"en","type":"article","venue":"Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Medical Research Council","keywords":"Ouabain; Locus Ceruleus; Endocrinology; Internal medicine; Blood pressure; Saline; Medicine; Chemistry; Dopamine; Sodium","score_opus":0.06490612438915397,"score_gpt":0.3394308562898504,"score_spread":0.2745247319006965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012602467","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953222,0.00015167597,0.000022099432,0.000593989,0.000067813766,0.00020150638,0.0000032196408,0.000008786134,0.0036287014],"genre_scores_gemma":[0.9964658,0.00010263087,0.00011958312,0.00032478909,0.000160431,0.00002568166,0.000036140296,0.00002417147,0.0027407734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982252,0.00037127326,0.00015488907,0.000415762,0.00036036162,0.00047248552],"domain_scores_gemma":[0.999378,0.00008484114,0.000015729962,0.00034450402,0.00008715161,0.000089766036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012516013,0.00011259656,0.000126065,0.000100473044,0.00012778076,0.00003825865,0.00023397467,0.00016206362,0.0006170158],"category_scores_gemma":[0.00019550727,0.00010469874,0.00006664466,0.00021281581,0.000050296632,0.0000057303187,0.00010976958,0.00034773513,0.00008291929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001507873,0.000091413895,0.0001533562,0.000004596173,0.000006954794,0.000020683516,0.000028901608,0.00002165903,0.9589751,0.000051235,0.0022490984,0.03824623],"study_design_scores_gemma":[0.0011817594,0.00073156034,0.013718568,0.000030875104,0.0000019392403,0.000039193306,0.00013132936,0.0007061439,0.89495856,0.0005005763,0.08770789,0.0002915854],"about_ca_topic_score_codex":0.00023556592,"about_ca_topic_score_gemma":0.000059267077,"teacher_disagreement_score":0.08545879,"about_ca_system_score_codex":0.000023585162,"about_ca_system_score_gemma":0.00010660744,"threshold_uncertainty_score":0.675589},"labels":[],"label_agreement":null},{"id":"W2012740651","doi":"10.1016/s0924-977x(00)80206-0","title":"The SSRI/5-HT2A antagonist YM992 produces inverse effects compared to SSRIs on the firing activity of noradrenergic neurons","year":2000,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Antagonist; Inverse; Pharmacology; Medicine; Internal medicine; Chemistry; Mathematics; Receptor","score_opus":0.01323793952856207,"score_gpt":0.26145923853171366,"score_spread":0.2482212990031516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012740651","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99185073,0.00012333671,0.000041780477,0.0015653186,0.0011042719,0.00054652523,0.000010552532,0.00004640912,0.0047110873],"genre_scores_gemma":[0.9947269,0.00036281865,0.00004106731,0.0030881206,0.00048201595,0.000029883442,0.0000064960172,0.000086381544,0.0011763346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971138,0.001352812,0.00029409834,0.000610031,0.00018622002,0.00044303323],"domain_scores_gemma":[0.99884564,0.00017983266,0.00014125755,0.0006339949,0.00005729358,0.00014200379],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049804867,0.00028417818,0.00021987627,0.000043938224,0.00039708283,0.00005293251,0.0007373193,0.000045590332,0.00012532166],"category_scores_gemma":[0.00010122696,0.00018781848,0.00014530741,0.00022158939,0.0001870852,0.0000055390205,0.00015552777,0.00030070628,0.00010322054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007333551,0.00012544582,0.000042347812,0.0000109824405,0.00005302925,0.00003189958,0.00008447464,0.0013506861,0.96832913,0.000036499703,0.01239153,0.016810628],"study_design_scores_gemma":[0.00096032117,0.0010846893,0.0051759765,0.000017094755,0.000041232004,0.000018773433,0.000018228098,0.00022994154,0.8087955,0.000013499699,0.18337275,0.00027198746],"about_ca_topic_score_codex":0.000007940839,"about_ca_topic_score_gemma":0.000009257155,"teacher_disagreement_score":0.17098123,"about_ca_system_score_codex":0.000010033876,"about_ca_system_score_gemma":0.000031205796,"threshold_uncertainty_score":0.76590157},"labels":[],"label_agreement":null},{"id":"W2013053016","doi":"10.1016/s0006-2952(01)00726-2","title":"Apparent capacity of cardiac muscarinic receptors for different radiolabeled antagonists","year":2001,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Muscarinic acetylcholine receptor; Radioligand; Chemistry; Tropane; Receptor; Radioligand Assay; Parasympatholytic; Stereochemistry; Biochemistry","score_opus":0.020494192634561776,"score_gpt":0.2816878181530302,"score_spread":0.2611936255184684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013053016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946169,0.0016144594,0.0014608839,0.000107991975,0.0015567235,0.00047347578,0.000058681017,0.000018521234,0.0000923209],"genre_scores_gemma":[0.99675083,0.0008607241,0.00088139594,0.00016481274,0.0007552685,0.00012827959,0.00023837305,0.000029104356,0.00019121997],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986061,0.000080440375,0.00035716518,0.00045215763,0.000115253155,0.00038891874],"domain_scores_gemma":[0.99934024,0.000042935208,0.0001400508,0.00020481419,0.000114232644,0.00015771497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001719698,0.00022815674,0.0003792761,0.000042669115,0.00006360204,0.000006849802,0.00024729187,0.00027640737,0.00031465234],"category_scores_gemma":[0.00004611179,0.00020788671,0.00028950805,0.00007658713,0.00012792378,0.0000024953188,0.000101675694,0.00011389227,0.0000027716335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036052696,0.0001591339,0.0005417338,0.000034125085,0.0001684264,3.8153462e-7,0.00002019671,0.000005031453,0.9493863,0.000040656727,0.04869956,0.00058391126],"study_design_scores_gemma":[0.0008546571,0.000347318,0.00009102761,0.0000066587495,0.000080297046,0.0000049373884,0.000018651546,0.00007081684,0.9234647,0.000076019955,0.07477063,0.00021428226],"about_ca_topic_score_codex":0.000010606969,"about_ca_topic_score_gemma":5.391562e-7,"teacher_disagreement_score":0.026071066,"about_ca_system_score_codex":0.00002866706,"about_ca_system_score_gemma":0.000040833896,"threshold_uncertainty_score":0.84773743},"labels":[],"label_agreement":null},{"id":"W2013087295","doi":"10.1021/bi701436w","title":"Trafficking of Preassembled Opioid μ−δ Heterooligomer−Gz Signaling Complexes to the Plasma Membrane:  Coregulation by Agonists","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Opioid; Chemistry; Membrane; Plasma; Biochemistry; Physics; Receptor","score_opus":0.008591033828127302,"score_gpt":0.24261225331629244,"score_spread":0.23402121948816512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013087295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99046713,0.0003399352,0.008397213,0.000045697074,0.00014260782,0.00021175115,0.00003814988,0.000020521335,0.00033701558],"genre_scores_gemma":[0.9976856,0.000018356213,0.0012016385,0.00010562547,0.00032109534,0.000012104534,0.0002768305,0.0000306463,0.00034809715],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861026,0.000026630485,0.00038579412,0.00038510995,0.00025895203,0.0003332823],"domain_scores_gemma":[0.9991848,0.00003556235,0.00017514716,0.00036341354,0.00011149166,0.00012961055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046100264,0.00021227538,0.00019750082,0.00003098168,0.0001401352,0.000038180577,0.00032503175,0.00020414933,0.000064857675],"category_scores_gemma":[0.000067236615,0.00018016616,0.0001281652,0.00014316801,0.00005489071,0.0000038256935,0.00008673102,0.000090238784,0.000005180963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013427096,0.000044689717,0.000122045734,0.000055036515,0.00004664062,9.2388774e-7,0.000087012864,0.00046235888,0.9959354,0.000016961547,0.0011604773,0.0019342103],"study_design_scores_gemma":[0.00032635062,0.00009226158,0.00008916827,0.000046506335,0.000017310222,0.000012685829,0.00016779001,0.00021423062,0.99312377,0.000008689094,0.0056831534,0.00021810098],"about_ca_topic_score_codex":0.000017510238,"about_ca_topic_score_gemma":0.000007598945,"teacher_disagreement_score":0.007218497,"about_ca_system_score_codex":0.000023909663,"about_ca_system_score_gemma":0.000050616625,"threshold_uncertainty_score":0.73469627},"labels":[],"label_agreement":null},{"id":"W2013479335","doi":"10.1159/000079102","title":"Linkage of M5 Muscarinic and α7-Nicotinic Receptor Genes on 15q13 to Schizophrenia","year":2004,"lang":"en","type":"article","venue":"Neuropsychobiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Schizophrenia (object-oriented programming); Genetics; Nicotinic agonist; Psychosis; Psychology; Biology; Neuroscience; Receptor; Psychiatry","score_opus":0.009326011254928547,"score_gpt":0.24669648135182207,"score_spread":0.23737047009689352,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013479335","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973986,0.00052765943,0.00037079075,0.0002724793,0.0007749549,0.00021878208,0.000023070626,0.00001807494,0.00039557953],"genre_scores_gemma":[0.99588627,0.0005448171,0.0019488524,0.0010594117,0.0003229743,0.000016739375,0.000038792343,0.00003531159,0.00014680722],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871325,0.00007163844,0.00029461968,0.00057068554,0.000071394206,0.00027838524],"domain_scores_gemma":[0.99928856,0.000022872986,0.00010076287,0.00040324082,0.000056923425,0.00012761787],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013949777,0.00020447146,0.00024896066,0.000082294486,0.000057182966,0.000010317571,0.00022488473,0.00022337059,0.00008802595],"category_scores_gemma":[0.000074998316,0.0001843722,0.00009355644,0.00010863261,0.000076989556,0.0000022848562,0.00011013697,0.00013838714,0.000060050977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028771584,0.00006382272,0.00030177887,0.000010218056,0.000026635884,0.0000014663136,0.00003300124,0.0000890277,0.99222285,0.0007505081,0.00017463636,0.0060383566],"study_design_scores_gemma":[0.0014695851,0.0035925738,0.0029574358,0.00003326406,0.000014993193,0.000025077188,0.000027347087,0.0000024180633,0.96262443,0.00030573952,0.028675605,0.00027151295],"about_ca_topic_score_codex":0.0000142851,"about_ca_topic_score_gemma":0.000013252615,"teacher_disagreement_score":0.029598383,"about_ca_system_score_codex":0.000006714186,"about_ca_system_score_gemma":0.000042861855,"threshold_uncertainty_score":0.751848},"labels":[],"label_agreement":null},{"id":"W2013550035","doi":"10.1016/j.ejphar.2009.12.022","title":"Characterization of C-terminal tail determinants involved in CRTH2 receptor trafficking: Identification of a recycling motif","year":2009,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Internalization; Receptor; 5-HT5A receptor; Enzyme-linked receptor; Insulin-like growth factor 2 receptor; Protease-activated receptor 2; Agonist; Biology; HEK 293 cells; Mutant; Cell biology; Biochemistry; Molecular biology; Insulin-like growth factor 1 receptor; Gene","score_opus":0.01687388142506826,"score_gpt":0.2783855655944997,"score_spread":0.26151168416943144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013550035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960661,0.00012623018,0.0029675763,0.000070934395,0.0006395984,0.00009368884,0.000005231,0.0000022096358,0.00002846521],"genre_scores_gemma":[0.9986627,0.0002937323,0.0005140354,0.00008071391,0.00038229153,5.2995625e-7,0.00001541628,0.000015316158,0.000035228197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99816734,0.00044330148,0.00097631407,0.00014956115,0.00011892375,0.00014458095],"domain_scores_gemma":[0.9985353,0.000012028821,0.0011154524,0.00008524515,0.00020379885,0.000048210968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011502925,0.0001093019,0.0002550299,0.00016952673,0.00002305584,0.0000076595215,0.00023658728,0.00005296681,0.00006839266],"category_scores_gemma":[0.00006424439,0.000106896216,0.00010495199,0.000113785805,0.000039686434,0.000015876183,0.000024832803,0.00013242822,0.0000017808634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031058394,0.00014931806,0.0005875955,0.00002114348,0.000021556685,0.000027056429,0.00024659187,0.0001407357,0.9826652,0.0000030894232,0.00005723635,0.0157699],"study_design_scores_gemma":[0.0010220604,0.0008324239,0.0076324195,0.000064498585,0.00003047754,0.000032426444,0.00005915532,0.00021129622,0.98932874,0.000005208449,0.0006941813,0.00008711367],"about_ca_topic_score_codex":4.1456266e-7,"about_ca_topic_score_gemma":5.056016e-7,"teacher_disagreement_score":0.015682789,"about_ca_system_score_codex":0.000013301686,"about_ca_system_score_gemma":0.000051426774,"threshold_uncertainty_score":0.4359101},"labels":[],"label_agreement":null},{"id":"W2013708918","doi":"10.1139/cjpp-2012-0399","title":"Elevated dopamine D2 receptor in prefrontal cortex of CUMS rats is associated with downregulated cAMP-independent signaling pathway","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"University of Science and Technology of China","keywords":"CREB; Dopaminergic; Endocrinology; Prefrontal cortex; Internal medicine; Dopamine; Dopamine receptor D2; Chronic stress; Dopamine receptor; Receptor; Psychology; Neuroscience; Medicine; Chemistry; Transcription factor; Biochemistry","score_opus":0.00693458934969586,"score_gpt":0.21530990873938163,"score_spread":0.2083753193896858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013708918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99860024,0.00065372424,0.000033198627,0.00011728901,0.0003243047,0.00020567124,0.000037259626,0.0000020241537,0.000026312984],"genre_scores_gemma":[0.999151,0.000060315095,0.000092863374,0.00036368673,0.00013152898,0.000008833955,0.00006601483,0.00001837,0.00010741563],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864584,0.00022289794,0.00044517897,0.0002339127,0.00007705643,0.00037512157],"domain_scores_gemma":[0.9988903,0.00003690254,0.00038825232,0.00008496172,0.00029957297,0.0003000008],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00026314237,0.00018674119,0.00040725947,0.00016570624,0.0000722219,0.00000886299,0.0001754572,0.00028681755,0.0033513072],"category_scores_gemma":[0.000026192853,0.00015483829,0.000069410205,0.00012497888,0.00017924071,0.000015805323,0.000021123118,0.00028038077,0.0000033132305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001829654,0.00004581867,0.0012333952,0.000016246735,0.0002505615,0.00002487131,0.00019733689,0.00020154378,0.9969219,0.000008693933,0.00068988977,0.00022675724],"study_design_scores_gemma":[0.0016155214,0.0011079614,0.005652329,0.000042626492,0.000039437466,0.000049731523,0.00012735381,0.00010725804,0.99049807,0.00010728498,0.00047786153,0.0001745551],"about_ca_topic_score_codex":0.0007148499,"about_ca_topic_score_gemma":0.001258657,"teacher_disagreement_score":0.0064238403,"about_ca_system_score_codex":0.000047120517,"about_ca_system_score_gemma":0.000531112,"threshold_uncertainty_score":0.9975598},"labels":[],"label_agreement":null},{"id":"W2013857696","doi":"10.1074/jbc.m003657200","title":"beta sub2 -Adrenergic receptor internalization, endosomal sorting and plasma membrane recycling are regulated by Rab GTPases","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Rab; Internalization; Endosome; GTPase; Cell biology; Adrenergic receptor; BETA (programming language); Chemistry; Receptor; Biology; Intracellular; Biochemistry; Computer science","score_opus":0.01097610945579352,"score_gpt":0.22207233568115425,"score_spread":0.21109622622536073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013857696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969629,0.0021698747,0.00024470402,0.0000973439,0.00008773732,0.000046924673,0.000016602833,0.000012021197,0.00036190747],"genre_scores_gemma":[0.9952453,0.0024239474,0.0008082347,0.00011116224,0.000490407,0.0000023157304,0.00009887908,0.00001844592,0.0008013256],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856925,0.00007049106,0.000639811,0.00030351616,0.00016198315,0.00025492036],"domain_scores_gemma":[0.9990155,0.000035830624,0.00050112035,0.00013652038,0.0001347076,0.00017633555],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00030874924,0.00021659443,0.00033842304,0.000018616154,0.000101121506,0.000049224884,0.00022976576,0.0003011321,0.001538006],"category_scores_gemma":[0.00018634318,0.00016414135,0.0001592727,0.00007770937,0.00009263598,0.000010374142,0.000055576587,0.00022458173,0.0000022393738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029378236,0.000061105406,0.0020092942,0.000022674678,0.00007157826,0.00001383325,0.000010194598,0.0001101451,0.9935543,0.0000026671842,0.0005426795,0.0033077744],"study_design_scores_gemma":[0.00077664596,0.00021121354,0.00009150537,0.000106405016,0.000022160813,0.00026033496,0.00007875262,0.00010617641,0.9911722,0.000041608146,0.0069260816,0.0002069253],"about_ca_topic_score_codex":0.0000028332688,"about_ca_topic_score_gemma":3.4034795e-7,"teacher_disagreement_score":0.006383402,"about_ca_system_score_codex":0.000018064142,"about_ca_system_score_gemma":0.00002915098,"threshold_uncertainty_score":0.99937475},"labels":[],"label_agreement":null},{"id":"W2013989605","doi":"10.1210/me.2004-0080","title":"Functional Rescue of the Constitutively Internalized V2 Vasopressin Receptor Mutant R137H by the Pharmacological Chaperone Action of SR49059","year":2004,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Biology; Endocytosis; Arginine vasopressin receptor 2; Receptor; Cell biology; Vasopressin receptor; Nephrogenic diabetes insipidus; Vasopressin; Intracellular; Mutant; G protein-coupled receptor; Endocrinology; Antagonist; Signal transduction; Biochemistry; Gene","score_opus":0.021109450963737845,"score_gpt":0.26762632965778343,"score_spread":0.2465168786940456,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013989605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97266346,0.0010313751,0.024396213,0.0006628403,0.00060650887,0.0002750797,0.000044422126,0.000010211156,0.00030988688],"genre_scores_gemma":[0.9987708,0.000209976,0.00034776668,0.00037850003,0.00007277986,0.000039107577,0.000033719964,0.000014670166,0.00013270102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986837,0.00020407306,0.0003278044,0.00031104116,0.0001989802,0.00027442034],"domain_scores_gemma":[0.99936,0.000019172716,0.00019065288,0.00027364073,0.000114965434,0.000041569685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012518704,0.00017039718,0.00021838438,0.000030773503,0.000100608275,0.000007454908,0.0003566822,0.00014121474,0.0002674789],"category_scores_gemma":[0.00009096307,0.000106666055,0.0001976411,0.00009745992,0.0004916938,0.0000044162744,0.00021142859,0.00020730121,0.0000051196803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025436148,0.000114073504,0.000054991826,0.000008983125,0.000190574,0.0000043188447,0.000031095187,0.0006498149,0.9932222,0.0042887726,0.0003168643,0.0008639625],"study_design_scores_gemma":[0.0014058574,0.00027738715,0.00010385118,0.000019494464,0.000055153578,0.00008659323,0.00008738361,0.0000127229705,0.9881634,0.00038131903,0.009297311,0.00010954293],"about_ca_topic_score_codex":0.00007376325,"about_ca_topic_score_gemma":0.0000082140195,"teacher_disagreement_score":0.026107315,"about_ca_system_score_codex":0.000028675382,"about_ca_system_score_gemma":0.00010145917,"threshold_uncertainty_score":0.43497154},"labels":[],"label_agreement":null},{"id":"W2014145818","doi":"10.1016/j.coph.2004.08.001","title":"Pharmacological chaperone action on G-protein-coupled receptors","year":2004,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Endoplasmic reticulum; Receptor; Chaperone (clinical); Protein folding; G protein-coupled receptor; Cell biology; Biology; ER retention; Chemistry; Biochemistry; Medicine; Gene; Mutant","score_opus":0.13337228800870765,"score_gpt":0.4377558151867876,"score_spread":0.3043835271780799,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014145818","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00059910846,0.9692935,0.00025835016,0.000040419716,0.02800107,0.0016831567,0.000029913124,0.000043303266,0.000051227726],"genre_scores_gemma":[0.00027019516,0.9938901,0.00007679768,0.000045350615,0.0035762985,0.00097321055,0.00096244307,0.00008563587,0.00011993676],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967244,0.0004861867,0.00083234493,0.0010831483,0.00023551361,0.00063838105],"domain_scores_gemma":[0.9990085,0.000044367625,0.00045231672,0.0002402954,0.00005973127,0.00019480988],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041257602,0.0006832356,0.0011148347,0.00032210725,0.00011332959,0.000024828605,0.00050011644,0.0008042327,0.0020705003],"category_scores_gemma":[0.00003915126,0.000598907,0.00049008516,0.0003125684,0.00010087863,0.000007087345,0.00020546165,0.0010262865,0.00020032436],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026095612,0.0010323101,8.7981306e-7,0.011120368,0.00033015764,0.0000058090104,0.000027574111,0.00015236592,0.037201546,0.00027985655,0.0071987873,0.94238937],"study_design_scores_gemma":[0.0013105655,0.00060405035,2.7934473e-7,0.0041142134,0.00015281746,0.000017049953,0.000007563757,0.00002512047,0.0056288503,0.000039904877,0.9875045,0.00059512275],"about_ca_topic_score_codex":0.000003618459,"about_ca_topic_score_gemma":4.3885828e-7,"teacher_disagreement_score":0.9803057,"about_ca_system_score_codex":0.0002961543,"about_ca_system_score_gemma":0.00040839426,"threshold_uncertainty_score":0.99964625},"labels":[],"label_agreement":null},{"id":"W2014168983","doi":"10.1096/fj.01-0272fje","title":"Elimination of vascular fibrointimal hyperplasia bysomatostatin receptor 1.4 selective agonist","year":2002,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital","funders":"Academy of Finland; Helsingin ja Uudenmaan Sairaanhoitopiiri","keywords":"Restenosis; Octreotide; Somatostatin; Somatostatin receptor; Intimal hyperplasia; Medicine; Receptor; Agonist; Progenitor cell; Internal medicine; Neointimal hyperplasia; Endocrinology; Hyperplasia; In vitro; Chemistry; Biology; Stent; Smooth muscle; Stem cell; Cell biology; Biochemistry","score_opus":0.009560314268017222,"score_gpt":0.21563451287826735,"score_spread":0.20607419861025011,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014168983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918986,0.00079331914,0.0060162386,0.00016972482,0.00019359704,0.00009605341,0.000013373448,0.0000048696825,0.00081422157],"genre_scores_gemma":[0.9963955,0.0003617947,0.0024928849,0.000060643713,0.00027077968,0.0000031885625,0.000018170087,0.000017777686,0.0003792416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911505,0.00012838694,0.00023514738,0.00013629183,0.00020256416,0.00018258691],"domain_scores_gemma":[0.9994326,0.000017753928,0.00018139501,0.00015879079,0.00014888284,0.000060527098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035273103,0.00011198641,0.00012349614,0.00003694835,0.00020957246,0.000037931135,0.00018734757,0.00007516344,0.00055836514],"category_scores_gemma":[0.00007966492,0.00008035353,0.00014816417,0.00008615851,0.000057008776,0.0000067559986,0.00003424037,0.0001575784,0.000023269118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032497985,0.00003881064,0.00013500106,0.000005630613,0.00007052236,0.0000013101454,0.00021967517,0.00016888604,0.9933298,0.000106322375,0.002773287,0.003118217],"study_design_scores_gemma":[0.00038051172,0.00035804813,0.00015948644,0.0000202583,0.000027457376,0.00015103888,0.00029042063,0.00068470044,0.9950907,0.00010523992,0.002627482,0.00010461654],"about_ca_topic_score_codex":0.0000040774985,"about_ca_topic_score_gemma":0.0000011195673,"teacher_disagreement_score":0.0044969167,"about_ca_system_score_codex":0.000016037615,"about_ca_system_score_gemma":0.000027768365,"threshold_uncertainty_score":0.6113706},"labels":[],"label_agreement":null},{"id":"W2014433838","doi":"10.1051/medsci/200622121017","title":"L’essai de proximité aux méthionines : une approche pour glaner les structures des récepteurs","year":2006,"lang":"fr","type":"article","venue":"médecine/sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Chemistry","score_opus":0.02811733405874187,"score_gpt":0.28056256318091305,"score_spread":0.25244522912217116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014433838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9408614,0.024652818,0.020886997,0.0024908353,0.0006576726,0.00027007711,0.00009913708,0.000043924912,0.010037107],"genre_scores_gemma":[0.924332,0.0005874704,0.05602742,0.0003280235,0.0018626082,0.000037603353,0.00012823645,0.000045292018,0.01665134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99736625,0.00021181638,0.0004138228,0.0007949384,0.00037376952,0.0008393937],"domain_scores_gemma":[0.9991503,0.00007487048,0.00019627243,0.0002483679,0.00019503415,0.00013516565],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007316915,0.00041024876,0.00030808646,0.00009912912,0.00092900055,0.00024281828,0.00061109336,0.000408038,0.0013461098],"category_scores_gemma":[0.00020526834,0.00033699104,0.00016750253,0.0005547213,0.0013607772,0.00002406206,0.00015280393,0.000202294,0.000019151903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044325225,0.00033862426,0.0153149245,0.00016003192,0.00006500267,0.000018541252,0.00020700786,0.00545232,0.8455653,0.07484717,0.030744934,0.027241776],"study_design_scores_gemma":[0.0013875806,0.0012487376,0.007799565,0.0002249442,0.00011634369,0.0002541961,0.0025837088,0.0018356949,0.6966388,0.16321471,0.123614065,0.0010816382],"about_ca_topic_score_codex":0.001440515,"about_ca_topic_score_gemma":0.00034259816,"teacher_disagreement_score":0.14892653,"about_ca_system_score_codex":0.000037968723,"about_ca_system_score_gemma":0.00046558667,"threshold_uncertainty_score":0.9999082},"labels":[],"label_agreement":null},{"id":"W2014443512","doi":"10.1152/ajpheart.00317.2009","title":"Chronic central versus systemic blockade of AT<sub>1</sub> receptors and cardiac dysfunction in rats post-myocardial infarction","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Losartan; Preload; Medicine; Internal medicine; Blockade; Myocardial infarction; Ejection fraction; Angiotensin II; Endocrinology; Blood pressure; Cardiology; Receptor; Heart failure; Hemodynamics","score_opus":0.005071888851566718,"score_gpt":0.20848074113260365,"score_spread":0.20340885228103692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014443512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964373,0.0024565745,0.0000043913747,0.00006016385,0.0008985741,0.00012590576,0.000006383462,0.0000049711625,0.0000057253005],"genre_scores_gemma":[0.9978478,0.0011310509,0.00003348023,0.000090853515,0.00084815256,0.0000035982005,0.000027178374,0.000015795917,0.0000020883463],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9983711,0.00033694928,0.00046325204,0.00036803036,0.00011273728,0.0003479216],"domain_scores_gemma":[0.99907875,0.000040775227,0.00043268543,0.00018855692,0.00013034255,0.00012887144],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024223757,0.0002197408,0.0006528594,0.00012776109,0.00007939079,0.0000053767412,0.00009025957,0.00018018649,0.0000089073355],"category_scores_gemma":[0.000035064826,0.00020481754,0.00020695644,0.00012755112,0.0003225527,0.000017986638,0.000049018345,0.00022777496,0.0000012428396],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009087667,0.000033343847,0.0009998895,0.000021386335,0.00015020168,1.7720124e-7,0.000101850674,0.00048438172,0.99408555,0.00002234598,0.000054117165,0.0031379606],"study_design_scores_gemma":[0.0012462583,0.004675628,0.5250315,0.000046459703,0.00007043629,0.000057404133,0.00031727104,0.00003062376,0.46783727,0.00008764404,0.00037190053,0.00022759227],"about_ca_topic_score_codex":0.000014936168,"about_ca_topic_score_gemma":0.0000030751896,"teacher_disagreement_score":0.52624834,"about_ca_system_score_codex":0.000079610705,"about_ca_system_score_gemma":0.00012820393,"threshold_uncertainty_score":0.83522165},"labels":[],"label_agreement":null},{"id":"W2014697956","doi":"10.1021/bi011746s","title":"Cooperativity and Oligomeric Status of Cardiac Muscarinic Cholinergic Receptors","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Muscarinic acetylcholine receptor; Chemistry; Digitonin; Receptor; Radioligand; Cooperativity; Cholinergic; Biophysics; Muscarinic acetylcholine receptor M2; Stereochemistry; Internal medicine; Endocrinology; Biochemistry; Biology; Enzyme","score_opus":0.011227637379326381,"score_gpt":0.22292958495730897,"score_spread":0.21170194757798258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014697956","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905628,0.006864181,0.000051399235,0.00001571553,0.00018527808,0.00007371692,0.00003120443,0.000011348681,0.0022043558],"genre_scores_gemma":[0.9933825,0.0040087905,0.0005802862,0.00003358788,0.00021924525,0.000010799244,0.000064720785,0.000019676329,0.0016803661],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990485,0.00003069793,0.00019765897,0.0003335429,0.00011259809,0.00027705918],"domain_scores_gemma":[0.9994045,0.000009225417,0.00008386513,0.00028783843,0.000065836386,0.0001487459],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000090668706,0.00016167648,0.00020239793,0.00001955843,0.000051791965,0.000014875143,0.00009731714,0.00017368166,0.00026574335],"category_scores_gemma":[0.00007235864,0.0001568632,0.00009075662,0.00009462051,0.000094691735,0.0000029729238,0.00008705143,0.000081081016,0.000004483825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001129639,0.000038752005,0.0013543533,0.000037745864,0.00003897327,3.572077e-7,0.00003440873,0.000008979934,0.99142003,0.000011175523,0.0013728649,0.0056710425],"study_design_scores_gemma":[0.00020659978,0.00009272932,0.0002201119,0.000012301639,0.000014118372,0.0000038281723,0.00007239596,0.000105790794,0.9830114,0.0000049555524,0.01607126,0.00018447146],"about_ca_topic_score_codex":0.000023305674,"about_ca_topic_score_gemma":7.036815e-7,"teacher_disagreement_score":0.014698395,"about_ca_system_score_codex":0.000012209031,"about_ca_system_score_gemma":0.000028021197,"threshold_uncertainty_score":0.6396696},"labels":[],"label_agreement":null},{"id":"W2014716705","doi":"10.1074/jbc.m410312200","title":"Constitutive Protease-activated Receptor-2-mediated Migration of MDA MB-231 Breast Cancer Cells Requires Both β-Arrestin-1 and -2","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Autocrine signalling; Cell biology; Cell migration; Biology; Gene silencing; Small interfering RNA; Cell culture; Molecular biology; Chemistry; Cancer research; Cell; Receptor; Biochemistry; Transfection","score_opus":0.014234003391295942,"score_gpt":0.24212954846487258,"score_spread":0.22789554507357665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014716705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99805474,0.0008847285,0.00047911468,0.00016755222,0.00009952687,0.000106556705,0.00010647897,0.000005839818,0.00009543183],"genre_scores_gemma":[0.99741715,0.0010835193,0.0010687173,0.00006252296,0.00028829862,0.0000059979566,0.000039397502,0.000008617575,0.00002579289],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990038,0.000040653635,0.00042979457,0.00021087533,0.0001391726,0.00017567597],"domain_scores_gemma":[0.99901277,0.000024887677,0.00049488415,0.00009956461,0.00022873927,0.00013917603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002079061,0.00016880943,0.00027837633,0.000019539373,0.000051722225,0.000015633676,0.00013553369,0.00029126756,0.00018635945],"category_scores_gemma":[0.00014581761,0.000119590986,0.0001073792,0.00007890096,0.00022932762,0.000009675314,0.00004831986,0.00018961726,6.9299995e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004045767,0.000094954514,0.0011241019,0.000035323235,0.00007064396,0.0000076218753,0.000024416366,0.0001002598,0.9975616,0.0000073357837,0.00015296502,0.00041623338],"study_design_scores_gemma":[0.0008085094,0.00028635774,0.0005444521,0.00013610668,0.000015833535,0.000098160446,0.00011827967,0.000004698506,0.9968912,0.00008573445,0.0008618464,0.00014882341],"about_ca_topic_score_codex":0.000044169683,"about_ca_topic_score_gemma":0.0000018703369,"teacher_disagreement_score":0.0007088813,"about_ca_system_score_codex":0.00003616365,"about_ca_system_score_gemma":0.00019629869,"threshold_uncertainty_score":0.4876779},"labels":[],"label_agreement":null},{"id":"W2015137255","doi":"10.1074/jbc.m113.473660","title":"Role of SAP97 Protein in the Regulation of Corticotropin-releasing Factor Receptor 1 Endocytosis and Extracellular Signal-regulated Kinase 1/2 Signaling","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"PDZ domain; Biology; Cell biology; HEK 293 cells; Small hairpin RNA; Gene knockdown; Internalization; Scaffold protein; Fluorescence recovery after photobleaching; Endocytosis; Receptor; Signal transduction; Biophysics; Cell culture; Biochemistry","score_opus":0.013766211564181712,"score_gpt":0.21894053659170223,"score_spread":0.20517432502752053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015137255","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964805,0.0028762883,0.00036067163,0.00004393841,0.000015300628,0.00019028156,0.000006821605,0.0000021681756,0.000023996217],"genre_scores_gemma":[0.9979087,0.00023220525,0.0016964405,0.000009783599,0.00010303252,0.0000065778995,0.000014560954,0.000009040681,0.00001963867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986484,0.0001227741,0.000685061,0.00017505321,0.00019512985,0.0001735525],"domain_scores_gemma":[0.99889165,0.00005205167,0.0006463761,0.00014024077,0.00020353738,0.00006613976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014109368,0.00015151736,0.00031296382,0.00003063943,0.000034310684,0.000019073834,0.00020221235,0.00024537763,0.00037994955],"category_scores_gemma":[0.00016970115,0.000096624215,0.00014071242,0.00009914704,0.000114296025,0.000011040358,0.000044339224,0.000185641,4.3992722e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012361213,0.00009256457,0.0009673503,0.00005033368,0.000033710956,0.0000011250445,0.000067111694,0.00006441788,0.99500275,0.000012047313,0.000008190707,0.0035767835],"study_design_scores_gemma":[0.00041445592,0.00037070867,0.0029994,0.00012905792,0.000012575809,0.000022858185,0.00042717034,0.0001319709,0.9949137,0.0003398062,0.00012787385,0.000110397814],"about_ca_topic_score_codex":0.0000117737345,"about_ca_topic_score_gemma":1.5938234e-7,"teacher_disagreement_score":0.0034663856,"about_ca_system_score_codex":0.000014897147,"about_ca_system_score_gemma":0.000038946746,"threshold_uncertainty_score":0.4160181},"labels":[],"label_agreement":null},{"id":"W2015176102","doi":"10.1038/sj.tpj.6500208","title":"The human dopamine D4 receptor repeat sequences modulate expression","year":2003,"lang":"en","type":"article","venue":"The Pharmacogenomics Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":217,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Canada Research Chairs","keywords":"Biology; Genetics; Reporter gene; Untranslated region; Luciferase; Exon; Gene; Gene expression; Molecular biology; Messenger RNA; Transfection","score_opus":0.018364017202876757,"score_gpt":0.2789006033863533,"score_spread":0.2605365861834765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015176102","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917329,0.003595843,0.0023507297,0.00032177326,0.0008806747,0.00013517213,0.00000597796,0.0000075423127,0.0009694029],"genre_scores_gemma":[0.99280304,0.0037480863,0.0005829163,0.00022725099,0.00086414604,0.000008208882,0.000008918786,0.000030417725,0.0017269988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870026,0.00029496726,0.00031116587,0.00019802837,0.00017029658,0.00032526965],"domain_scores_gemma":[0.9992819,0.000024656041,0.00021557527,0.00027016507,0.00008811746,0.00011958188],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0013102373,0.00016458624,0.00010812809,0.000020372003,0.0013171277,0.00015227227,0.0004761992,0.00006344988,0.00024516412],"category_scores_gemma":[0.000045181423,0.000089925066,0.00014363845,0.000050653267,0.00009123928,0.0000070827664,0.000074597476,0.00028977485,0.000015282038],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037675964,0.000014638608,0.000045879187,0.0000014688243,0.000054333745,0.0000034676905,0.000055907123,0.0005598337,0.995393,0.00027693648,0.0014043915,0.0021524872],"study_design_scores_gemma":[0.00035518123,0.00006612501,0.0000048236643,0.00000791666,0.00001962554,0.00021007433,0.0001239808,0.00006755425,0.8335567,0.0010845918,0.16437976,0.00012366699],"about_ca_topic_score_codex":0.0000026961825,"about_ca_topic_score_gemma":0.0000017698807,"teacher_disagreement_score":0.16297537,"about_ca_system_score_codex":0.000032817406,"about_ca_system_score_gemma":0.000060420345,"threshold_uncertainty_score":0.999983},"labels":[],"label_agreement":null},{"id":"W2015370039","doi":"10.1016/j.cellsig.2009.02.008","title":"G protein-coupled receptors stimulation and the control of cell migration","year":2009,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":193,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"G protein-coupled receptor; Cell biology; Heterotrimeric G protein; Cell migration; Biology; Signal transduction; Actin cytoskeleton; G protein; G protein-coupled receptor kinase; Chemotaxis; Receptor; Cytoskeleton; Cell; Biochemistry","score_opus":0.013396493632366143,"score_gpt":0.2378908653372297,"score_spread":0.22449437170486355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015370039","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017793502,0.9000593,0.096696384,0.000007482296,0.000099805555,0.0012967448,0.000005606511,0.000008409579,0.000046947647],"genre_scores_gemma":[0.0469733,0.9510862,0.0008783405,0.00001789638,0.00033054478,0.0000715937,0.00029150155,0.000048869064,0.00030172084],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982779,0.00029765867,0.0006312022,0.00040322397,0.00019017246,0.00019986248],"domain_scores_gemma":[0.9989102,0.00006300529,0.0005978432,0.00027175777,0.00010187526,0.00005530777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007702331,0.00033489944,0.0008558444,0.00006771067,0.00010898325,0.0000441052,0.00020842027,0.0003977259,0.0000381518],"category_scores_gemma":[0.000051707706,0.00022775696,0.00040298473,0.00010511677,0.00007651987,0.0000040576047,0.000033717715,0.00019916912,0.0000035093133],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012483144,0.000051123607,6.975606e-7,0.0030373542,0.00018598267,0.000001836716,0.00007196394,0.0005555134,0.8137264,0.00033569004,0.000020536902,0.18188804],"study_design_scores_gemma":[0.0036748843,0.0006502223,1.4261907e-7,0.00523322,0.0018027672,0.000008422315,0.0000582109,0.012296971,0.37667352,0.0004906489,0.59801775,0.0010932651],"about_ca_topic_score_codex":0.000009948798,"about_ca_topic_score_gemma":0.0000015883868,"teacher_disagreement_score":0.5979972,"about_ca_system_score_codex":0.000013452106,"about_ca_system_score_gemma":0.00009837689,"threshold_uncertainty_score":0.92876595},"labels":[],"label_agreement":null},{"id":"W2015551920","doi":"10.1097/00004647-200002000-00011","title":"Muscarinic—but Not Nicotinic—Acetylcholine Receptors Mediate a Nitric Oxide-Dependent Dilation in Brain Cortical Arterioles: A Possible Role for the M5 Receptor Subtype","year":2000,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Muscarinic acetylcholine receptor; Neuroscience; Muscarinic acetylcholine receptor M4; Acetylcholine; Nicotinic agonist; Acetylcholine receptor; Muscarinic acetylcholine receptor M3; Medicine; Muscarinic acetylcholine receptor M1; Receptor; Muscarinic acetylcholine receptor M2; Nitric oxide; Psychology; Pharmacology; Internal medicine","score_opus":0.008548222618881909,"score_gpt":0.23526340647582217,"score_spread":0.22671518385694026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015551920","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921682,0.0045237294,0.0013065896,0.0006503462,0.0008017543,0.0004373298,0.000046782992,0.000011139654,0.00005413067],"genre_scores_gemma":[0.9883318,0.0028606674,0.0049771117,0.0007845423,0.0020071592,0.00003641448,0.00005319431,0.00006914232,0.0008799724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99712074,0.00030278196,0.0011699019,0.0003965113,0.0004817966,0.0005282628],"domain_scores_gemma":[0.9984825,0.00018454136,0.0004931297,0.00035835,0.00025299232,0.00022843691],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017259789,0.00033013723,0.00059946673,0.00016280959,0.00014482198,0.00010635413,0.0005083632,0.00032330232,0.00075039803],"category_scores_gemma":[0.00051172083,0.00023899162,0.00048178816,0.00026267985,0.000067264984,0.000043886543,0.00006831753,0.0005359065,0.000020110418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013660501,0.0003336568,0.00086547143,0.000018813924,0.00031439186,0.0000040957934,0.00027511662,0.0011713636,0.96850944,0.00008249022,0.0010520151,0.026007103],"study_design_scores_gemma":[0.010535206,0.0009652207,0.014061434,0.00012457915,0.00065813016,0.00018984785,0.0006687,0.0028103604,0.9130782,0.00048349786,0.055634815,0.00079000153],"about_ca_topic_score_codex":0.00003043369,"about_ca_topic_score_gemma":0.000046160214,"teacher_disagreement_score":0.055431224,"about_ca_system_score_codex":0.000024965417,"about_ca_system_score_gemma":0.00022457835,"threshold_uncertainty_score":0.9745795},"labels":[],"label_agreement":null},{"id":"W2015558821","doi":"10.1051/medsci/2010268-9734","title":"Sélectivité fonctionnelle des ligands des récepteurs opiacés","year":2010,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Chemistry","score_opus":0.05425955489463237,"score_gpt":0.3197339843992767,"score_spread":0.26547442950464434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015558821","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.06846204,0.91097903,0.008469296,0.00008176719,0.0029244807,0.00051303336,0.000040158247,0.000037569585,0.008492606],"genre_scores_gemma":[0.025878945,0.95506036,0.010485588,0.00013907025,0.0021639343,0.00010159971,0.00007457683,0.000089858266,0.006006078],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960528,0.00022003124,0.00076778827,0.0014279761,0.0004875213,0.0010438812],"domain_scores_gemma":[0.99839836,0.0001532573,0.00043759437,0.00049982656,0.00020859843,0.00030236333],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015227965,0.0008079582,0.0010694026,0.00022978074,0.0019475835,0.00035315764,0.00108162,0.0009951519,0.0016614316],"category_scores_gemma":[0.00040209075,0.0006558688,0.00075642293,0.00091541855,0.0026035134,0.000034741966,0.00034605488,0.00059158274,0.00019215864],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017300737,0.00033029827,0.0014316472,0.0017700795,0.00016215778,0.0000097892225,0.00016125676,0.000121542405,0.12459999,0.0038513234,0.0010129625,0.86653167],"study_design_scores_gemma":[0.00054272776,0.0020628087,0.00011873753,0.0025759563,0.00032677368,0.00027047403,0.00031959513,0.00009669213,0.08167107,0.0060318806,0.9048226,0.0011607123],"about_ca_topic_score_codex":0.00011867429,"about_ca_topic_score_gemma":0.00017230795,"teacher_disagreement_score":0.9038096,"about_ca_system_score_codex":0.00007455187,"about_ca_system_score_gemma":0.00073672,"threshold_uncertainty_score":0.99958926},"labels":[],"label_agreement":null},{"id":"W2016472471","doi":"10.1038/jcbfm.2008.110","title":"Evaluation of the Novel 5-HT <sub>4</sub> Receptor PET Ligand [ <sup>11</sup> C]SB207145 in the Göttingen Minipig","year":2008,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Electrical, Communications and Cyber Systems; McGill University","keywords":"Radioligand; Binding potential; Receptor; Striatum; In vivo; Ligand (biochemistry); Radioligand Assay; 5-HT receptor; Positron emission tomography; Human brain; Chemistry; Binding site; Biophysics; Biology; Serotonin; Endocrinology; Neuroscience; Biochemistry","score_opus":0.018930273468534528,"score_gpt":0.23504789800057177,"score_spread":0.21611762453203726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016472471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950836,0.003304015,0.00021014683,0.00036625125,0.0005501071,0.00030753628,0.000021675014,0.0000027319606,0.00015395405],"genre_scores_gemma":[0.9956412,0.0005235566,0.0020815306,0.00029518455,0.0013707993,0.000010921156,0.000011358159,0.000031055977,0.000034410936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968222,0.00053083006,0.0008434502,0.00025572823,0.0012260485,0.00032174223],"domain_scores_gemma":[0.9980707,0.000048005993,0.0006753109,0.00041229764,0.0007048261,0.00008885572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0034780777,0.0002531999,0.00043711747,0.00010966412,0.00015981503,0.000034562272,0.0006561493,0.00016952683,0.000061792845],"category_scores_gemma":[0.00053570815,0.00015377508,0.00043943708,0.0002902886,0.000100390724,0.000027755255,0.00009974367,0.0003525948,0.0000035875657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059695092,0.0002690916,0.0006849059,0.000011003092,0.00019740575,0.000004104163,0.0009412388,0.0024186221,0.9917762,0.000054242148,0.0009797359,0.002603707],"study_design_scores_gemma":[0.0030284422,0.00017712204,0.0045795813,0.00006313756,0.00057433057,0.00045118784,0.00042316603,0.001117934,0.98511904,0.00016955516,0.004098088,0.00019843958],"about_ca_topic_score_codex":0.0000114508,"about_ca_topic_score_gemma":0.00001796135,"teacher_disagreement_score":0.0066572325,"about_ca_system_score_codex":0.000017152362,"about_ca_system_score_gemma":0.00039954035,"threshold_uncertainty_score":0.62707657},"labels":[],"label_agreement":null},{"id":"W2016844184","doi":"10.1016/j.cellsig.2009.09.023","title":"Structural determinants underlying constitutive dimerization of unoccupied human follitropin receptors","year":2009,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Alanine; Receptor; G protein-coupled receptor; Glycan; Chemistry; Residue (chemistry); Extracellular; Context (archaeology); Glycoprotein; Cell biology; Biophysics; Glycosylation; Biochemistry; Stereochemistry; Biology; Amino acid","score_opus":0.02756077361844056,"score_gpt":0.27980855701810203,"score_spread":0.2522477833996615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016844184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8890294,0.0005386845,0.10975898,0.0000058909613,0.00021621496,0.00016674225,0.0000038888984,0.000015684016,0.00026454485],"genre_scores_gemma":[0.99749815,0.00003001486,0.002060694,0.000043281103,0.00012139437,0.0000029029661,0.00013121034,0.000017942806,0.00009443045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882585,0.00006559143,0.0003607303,0.0003342571,0.00016164652,0.00025195233],"domain_scores_gemma":[0.9994297,0.000009224159,0.00020686438,0.00018621508,0.00009516642,0.000072850904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001506536,0.00018972384,0.00022950135,0.00006419636,0.00018838889,0.000027265603,0.00017760824,0.00016005432,0.000077879304],"category_scores_gemma":[0.000029592724,0.00018820053,0.00012808302,0.00011010996,0.00007155616,0.000009324473,0.000030014091,0.000091404305,0.000002284448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030809,0.000014732063,0.00051895337,0.000012902357,0.000027174745,0.00000318163,0.00009286464,0.0011844679,0.9939546,0.0010218722,0.0000069891557,0.0031314248],"study_design_scores_gemma":[0.0003750443,0.00029783865,0.00013580361,0.000060383038,0.000026758507,0.0000028078089,0.000107915075,0.0013592337,0.9961613,0.0011139939,0.00013050572,0.00022842608],"about_ca_topic_score_codex":0.000011031316,"about_ca_topic_score_gemma":0.0000031493196,"teacher_disagreement_score":0.108468756,"about_ca_system_score_codex":0.000016689013,"about_ca_system_score_gemma":0.00005001058,"threshold_uncertainty_score":0.7674595},"labels":[],"label_agreement":null},{"id":"W2016877626","doi":"10.1016/j.cell.2012.09.003","title":"Restructuring G-Protein- Coupled Receptor Activation","year":2012,"lang":"en","type":"review","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":261,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canada Research Chairs","keywords":"Rhodopsin; G protein-coupled receptor; Biology; Receptor; Signal transduction; Computational biology; Cell biology; Homology modeling; Structural biology; Genetics; Biochemistry; Retinal","score_opus":0.03084454737060662,"score_gpt":0.2713114264055719,"score_spread":0.24046687903496525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016877626","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012059022,0.996241,0.00073551654,0.0000021142682,0.00044189394,0.000470793,0.000010182428,0.000017449254,0.00087516743],"genre_scores_gemma":[0.0005342389,0.99304765,0.0012835632,0.000015958605,0.0013197156,0.00007583218,0.00070815097,0.000085706124,0.0029291832],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988283,0.00008033315,0.0003032146,0.00037568813,0.00012191763,0.0002905601],"domain_scores_gemma":[0.99919325,0.000009347212,0.00026667753,0.00039447195,0.000037613667,0.00009862446],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016886169,0.00031026054,0.0004848584,0.000051585732,0.00007762335,0.00003154159,0.00023272226,0.000510936,0.00047685351],"category_scores_gemma":[0.00001994238,0.00026606166,0.0002782812,0.00007292754,0.000017867693,0.0000033125173,0.00010364508,0.00020648439,0.00012744417],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009276575,0.0000280378,1.753798e-7,0.0047555487,0.00006414501,4.3459488e-7,0.000012689259,0.0000014863397,0.60040504,0.00003486675,0.00045409202,0.39423424],"study_design_scores_gemma":[0.0000732125,0.000034579563,5.9559202e-8,0.00067089644,0.00007455022,0.0000016649137,0.0000045249144,8.3164235e-7,0.20225786,0.000008865108,0.79661894,0.00025399998],"about_ca_topic_score_codex":0.0000057104025,"about_ca_topic_score_gemma":3.7141405e-7,"teacher_disagreement_score":0.7961649,"about_ca_system_score_codex":0.00003401689,"about_ca_system_score_gemma":0.000102143764,"threshold_uncertainty_score":0.99997914},"labels":[],"label_agreement":null},{"id":"W2016903201","doi":"10.1038/npp.2014.295","title":"Involvement of Cholinergic System in Hyperactivity in Dopamine-Deficient Mice","year":2014,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Novartis Pharma; Astellas Foundation for Research on Metabolic Disorders; Astellas Pharma; H. Lundbeck A/S; Smoking Research Foundation; Shionogi; Ono Pharmaceutical; Eisai; Valeant Pharmaceuticals International; Sunovion; Pfizer; Teva Pharmaceutical Industries; Ministry of Health, Labour and Welfare; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Dopaminergic; Clozapine; Dopamine; Psychosis; Haloperidol; Antipsychotic; Acetylcholine; Choline acetyltransferase; Psychology; Internal medicine; Medicine; Endocrinology; Pharmacology; Neuroscience; Schizophrenia (object-oriented programming); Psychiatry","score_opus":0.01032998607590581,"score_gpt":0.2638813632720265,"score_spread":0.2535513771961207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016903201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99739164,0.00015191229,0.00034418935,0.00004626321,0.00080612063,0.0002041864,0.0000035579264,0.000008143118,0.0010439886],"genre_scores_gemma":[0.9992133,0.00007495765,0.00014910476,0.0003149376,0.00013704615,0.00003547926,0.000009745883,0.00001907171,0.000046397854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986517,0.00027560315,0.00034794008,0.00037472905,0.000101965445,0.00024809287],"domain_scores_gemma":[0.9995728,0.000031536667,0.000118945085,0.00018413433,0.000040772495,0.000051787254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040455864,0.00013779136,0.00022605588,0.00013229706,0.000017906481,0.00000449435,0.00017974114,0.0001037767,0.000033537777],"category_scores_gemma":[0.000030262201,0.00013767493,0.000055269404,0.00017019294,0.00003195908,0.0000032068556,0.00006618394,0.00015105774,0.000006748113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019012304,0.00020416622,0.003386289,0.000045516113,0.000006339932,0.000008326323,0.0000285216,0.0029456567,0.9918693,0.00009417859,0.00008853185,0.0011330596],"study_design_scores_gemma":[0.004437839,0.0007494223,0.013116509,0.00003782663,0.00001531899,0.0000244854,0.00014106785,0.0060523576,0.96685994,0.000015139255,0.008269463,0.00028061858],"about_ca_topic_score_codex":0.00005324569,"about_ca_topic_score_gemma":0.00003961686,"teacher_disagreement_score":0.025009338,"about_ca_system_score_codex":0.000024537567,"about_ca_system_score_gemma":0.000024535482,"threshold_uncertainty_score":0.56142205},"labels":[],"label_agreement":null},{"id":"W2016940132","doi":"10.1021/bi6026105","title":"Recovery of Oligomers and Cooperativity When Monomers of the M<sub>2</sub>Muscarinic Cholinergic Receptor Are Reconstituted into Phospholipid Vesicles","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cooperativity; Tetramer; Chemistry; Digitonin; Muscarinic acetylcholine receptor; Vesicle; Receptor; Biophysics; Agonist; Oxotremorine; Cooperative binding; Monomer; Muscarinic acetylcholine receptor M2; Phospholipid; Biochemistry; Binding site; Stereochemistry; Membrane; Biology; Enzyme","score_opus":0.006262227567756163,"score_gpt":0.20650463996665747,"score_spread":0.2002424123989013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016940132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972875,0.0016513083,0.00027826932,0.00004656622,0.00028195544,0.0001337665,0.00004174334,0.000008208114,0.00027064426],"genre_scores_gemma":[0.99831647,0.0005991494,0.00069973175,0.00006950218,0.00015877432,0.00000654246,0.000042600856,0.000020442007,0.00008679121],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988146,0.000034560893,0.00040208173,0.00037849645,0.00014298016,0.00022728957],"domain_scores_gemma":[0.99899316,0.000026822296,0.00032728366,0.00042034558,0.00013056763,0.00010182776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039353198,0.00020446835,0.00026517638,0.00003076228,0.00008241587,0.000012627961,0.00023504658,0.00026945022,0.000024997618],"category_scores_gemma":[0.00016045744,0.00017331513,0.00014907437,0.00013205608,0.00028164318,0.000007417854,0.00015727061,0.0001293871,0.0000010361895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013554537,0.000050722494,0.0013752203,0.00010207003,0.000072817544,4.7064276e-7,0.00006733659,0.000033922526,0.99262244,0.000009794856,0.00044743405,0.005082228],"study_design_scores_gemma":[0.0003984742,0.0000686664,0.00072098814,0.00008916513,0.000021945676,0.0000063417338,0.00030393183,0.000012120525,0.99756885,0.000038517086,0.00057487906,0.000196121],"about_ca_topic_score_codex":0.000031547777,"about_ca_topic_score_gemma":0.00001467328,"teacher_disagreement_score":0.0049464116,"about_ca_system_score_codex":0.000027475679,"about_ca_system_score_gemma":0.00012335411,"threshold_uncertainty_score":0.70675856},"labels":[],"label_agreement":null},{"id":"W2017113903","doi":"10.1194/jlr.m500500-jlr200","title":"Targeting the signaling pathway of acylation stimulating protein","year":2005,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; McGill University Health Centre","funders":"","keywords":"Wortmannin; Protein kinase B; Phospholipase C; MAPK/ERK pathway; Pertussis toxin; Phosphorylation; Chemistry; PI3K/AKT/mTOR pathway; LY294002; Kinase; Protein kinase A; Phosphatidylinositol; Signal transduction; Internal medicine; G protein; Cell biology; Endocrinology; Molecular biology; Biology; Biochemistry; Medicine","score_opus":0.04235915507887184,"score_gpt":0.33738031827116766,"score_spread":0.2950211631922958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017113903","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99060917,0.0007129041,0.007817362,0.00040579183,0.000076418626,0.00015292833,0.0000011775013,0.000001471536,0.00022275775],"genre_scores_gemma":[0.99149305,0.000029979758,0.0062531885,0.000016119027,0.0020307999,0.000002757311,0.0000022257097,0.0000135380415,0.00015832378],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835426,0.00031086616,0.000462317,0.00010302281,0.00054773473,0.00022182653],"domain_scores_gemma":[0.99877834,0.000083534986,0.00027986386,0.00012461067,0.00067754305,0.000056088782],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004427104,0.00006959906,0.00012720993,0.00008820028,0.00016495741,0.000034052344,0.0002590213,0.00008161111,0.000097549],"category_scores_gemma":[0.00070005737,0.000044946068,0.00010225396,0.00014294595,0.000051961986,0.000010802088,0.000084414205,0.00034738163,0.0000022941852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007472683,0.000029195071,0.00015889002,0.000015288657,0.00002443578,9.552662e-7,0.00016861632,0.012295187,0.9803893,0.000081852064,0.00017667915,0.006584873],"study_design_scores_gemma":[0.00026526122,0.00041578076,0.000021001644,0.000077788274,0.0000029177459,0.000007878609,0.00042060408,0.0022312375,0.9892502,0.0001053408,0.0071504638,0.00005152215],"about_ca_topic_score_codex":0.000003554115,"about_ca_topic_score_gemma":8.270834e-7,"teacher_disagreement_score":0.01006395,"about_ca_system_score_codex":0.00002031895,"about_ca_system_score_gemma":0.00014838697,"threshold_uncertainty_score":0.18328474},"labels":[],"label_agreement":null},{"id":"W2017145496","doi":"10.1042/bj20080867","title":"Rab11 regulates the recycling of the β2-adrenergic receptor through a direct interaction","year":2008,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"HEK 293 cells; Endosome; Receptor; Internalization; Cell biology; Agonist; Intracellular; Immunoprecipitation; Wild type; Biology; Mutant; Molecular biology; Chemistry; Biochemistry","score_opus":0.01801370421725908,"score_gpt":0.2420255593286459,"score_spread":0.2240118551113868,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017145496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99588406,0.0017286086,0.0005023401,0.00036779686,0.0007202088,0.00007855743,0.0000043600444,0.000006062896,0.0007080232],"genre_scores_gemma":[0.9964807,0.0010433741,0.0010120275,0.000185799,0.0008497554,0.000004168969,0.000009629192,0.00001770541,0.0003968307],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894506,0.00012144837,0.0003338895,0.00018801542,0.00021480383,0.00019677244],"domain_scores_gemma":[0.9992766,0.000033424873,0.00025270594,0.0002704167,0.00011360367,0.000053267715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026084916,0.00013649154,0.00015014391,0.000015372765,0.00028474518,0.000022027121,0.00034998756,0.000146647,0.00012418308],"category_scores_gemma":[0.0001911214,0.000074082534,0.0002742499,0.00011356637,0.00014243345,0.0000073209253,0.000107982654,0.0002637624,0.000003400088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008013675,0.000032099677,0.00017859862,0.0000036548481,0.000050129926,9.012614e-7,0.00010950053,0.000051173796,0.9905408,0.00003342077,0.008522128,0.00039744526],"study_design_scores_gemma":[0.00023448167,0.000072202696,0.00011176807,0.000055127563,0.000017533406,0.00029408102,0.000115023664,0.000027188618,0.9820198,0.00020717512,0.016742734,0.00010292977],"about_ca_topic_score_codex":0.000012462646,"about_ca_topic_score_gemma":8.926309e-7,"teacher_disagreement_score":0.008521057,"about_ca_system_score_codex":0.00002121273,"about_ca_system_score_gemma":0.00006594112,"threshold_uncertainty_score":0.3020998},"labels":[],"label_agreement":null},{"id":"W2017154349","doi":"10.1159/000124634","title":"Association of Diurnal Variations in Hypothalamic but Not Cortical Opiate ([ <sup>3</sup> H]-Naloxone)-Binding Sites with the Ability of Naloxone to Induce LH Release in the Prepubertal Female Rat","year":2008,"lang":"en","type":"article","venue":"Neuroendocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Medical Research Council","keywords":"Endocrinology; Internal medicine; Morning; Opiate; (+)-Naloxone; Diurnal temperature variation; Hypothalamus; Antagonist; Chemistry; Receptor; Biology; Medicine","score_opus":0.01913221486211006,"score_gpt":0.23795137345824424,"score_spread":0.21881915859613418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017154349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980352,0.00003684712,0.0003887011,0.0010286351,0.000053584725,0.00035211098,0.000018598543,0.0000049488594,0.00008137961],"genre_scores_gemma":[0.99912214,0.00009816983,0.00031788903,0.00022714121,0.000054787768,0.00004590975,0.000021082185,0.000013897042,0.00009895872],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981391,0.0005163037,0.0004257778,0.00033459754,0.00023428758,0.00034997732],"domain_scores_gemma":[0.9990435,0.00027930288,0.0002026952,0.00033043354,0.000103693405,0.00004036828],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015315379,0.00015052827,0.00026322153,0.00009394723,0.000101672595,0.000009496655,0.0002854441,0.00008399187,0.000024396104],"category_scores_gemma":[0.0005874491,0.00010376977,0.000076034274,0.0002337859,0.00010145504,0.000010148724,0.00009473351,0.0003355007,0.0000025187844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022741633,0.00018554654,0.09134791,0.00001167214,0.000031563308,0.000036836187,0.0005774457,0.0012976913,0.9058349,0.0003284697,0.00002443352,0.00009607994],"study_design_scores_gemma":[0.001297742,0.00086500996,0.25778124,0.000017035516,0.00004006906,0.0002653792,0.00048228138,0.0008512996,0.73801494,0.000056731966,0.00016041822,0.00016786341],"about_ca_topic_score_codex":0.00012382028,"about_ca_topic_score_gemma":0.00017517997,"teacher_disagreement_score":0.16781999,"about_ca_system_score_codex":0.000035339424,"about_ca_system_score_gemma":0.0000917528,"threshold_uncertainty_score":0.42316085},"labels":[],"label_agreement":null},{"id":"W2017260313","doi":"10.1016/j.bbamcr.2010.12.015","title":"Somatostatin receptor-3 mediated intracellular signaling and apoptosis is regulated by its cytoplasmic terminal","year":2010,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Transfection; Cell biology; Agonist; HEK 293 cells; Biology; Molecular biology; Signal transduction; Adenylyl cyclase; Apoptosis; Receptor; Cell culture; Biochemistry","score_opus":0.013510426693927725,"score_gpt":0.27756006296596814,"score_spread":0.2640496362720404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017260313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99681133,0.00048042077,0.00025839667,0.00096141256,0.00018025454,0.0006604367,0.00017957274,0.00005514007,0.0004130096],"genre_scores_gemma":[0.9947881,0.0006520185,0.0022221354,0.00035458474,0.0001844494,0.000076903234,0.0009012244,0.00015635762,0.00066421693],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9954287,0.0005503192,0.000575392,0.0013670038,0.00096866954,0.0011099555],"domain_scores_gemma":[0.9978313,0.00012968942,0.00022415278,0.0008457201,0.00044245512,0.00052670133],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011841485,0.0005623045,0.00044875903,0.00026684586,0.00040967186,0.0003098946,0.0007570392,0.0006913908,0.00030247826],"category_scores_gemma":[0.00020971269,0.00056059635,0.00022350358,0.0005592418,0.00038787688,0.000028615825,0.00052190217,0.0011526153,0.00009887165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017564326,0.00021912056,0.0000031430966,0.00008627725,0.00010861072,0.000009782763,0.00023451587,0.0000020311388,0.99433005,0.000068775174,0.004303811,0.00045824167],"study_design_scores_gemma":[0.00086526485,0.00053816923,0.0000071089135,0.000047988702,0.000033808246,0.000010262201,0.00016487851,0.00049051596,0.99100775,0.00010943337,0.0060875765,0.0006372582],"about_ca_topic_score_codex":0.0000397648,"about_ca_topic_score_gemma":0.000002317079,"teacher_disagreement_score":0.003322312,"about_ca_system_score_codex":0.000031395535,"about_ca_system_score_gemma":0.00026791327,"threshold_uncertainty_score":0.9996846},"labels":[],"label_agreement":null},{"id":"W2017566024","doi":"10.1074/jbc.m406921200","title":"C5L2 Is a Functional Receptor for Acylation-stimulating Protein","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":179,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Concordia University","funders":"","keywords":"Acylation; Chemistry; Biochemistry","score_opus":0.02984778295475205,"score_gpt":0.2639736915988155,"score_spread":0.23412590864406346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017566024","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9756572,0.0004438685,0.022941392,0.0004800434,0.00008390512,0.00011519693,0.000018525672,0.000005962117,0.00025390598],"genre_scores_gemma":[0.9768871,0.000023459452,0.019919917,0.00024854418,0.0022380664,0.0000116073115,0.000048076185,0.000011079992,0.0006121204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908966,0.000018111987,0.00039960063,0.00018487147,0.00013066137,0.00017708789],"domain_scores_gemma":[0.9992461,0.000028735061,0.0002922683,0.00009786964,0.00023880905,0.0000962233],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003233461,0.00012872668,0.00017408932,0.0000133882195,0.000081242964,0.000021789596,0.00014014276,0.00024750052,0.00089565176],"category_scores_gemma":[0.0002864711,0.000095206764,0.00023368798,0.00004118787,0.000033999157,0.0000065005893,0.00003687728,0.00013633881,0.0000046274113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022442828,0.000052360025,0.00020010868,0.0000138324,0.000040950446,3.9334714e-7,0.000009894604,0.00024525056,0.9943649,0.000015510182,0.0019500563,0.0028823004],"study_design_scores_gemma":[0.00059857505,0.00030243577,0.000047015623,0.000024439141,0.000008199935,0.00002526674,0.000036152473,0.00023397763,0.9473816,0.00017406898,0.051042363,0.00012588233],"about_ca_topic_score_codex":1.872726e-7,"about_ca_topic_score_gemma":6.7570305e-8,"teacher_disagreement_score":0.049092308,"about_ca_system_score_codex":0.000024810723,"about_ca_system_score_gemma":0.000062677704,"threshold_uncertainty_score":0.9806759},"labels":[],"label_agreement":null},{"id":"W2017631478","doi":"10.1016/j.tips.2008.10.009","title":"Recent methodological advances in the discovery of GPCR-associated protein complexes","year":2008,"lang":"en","type":"review","venue":"Trends in Pharmacological Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute; University of Toronto","funders":"Servier; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; European Genomic Institute for Diabetes","keywords":"G protein-coupled receptor; Drug discovery; Neuroscience; Computational biology; Psychology; Data science; Cognitive science; Medicine; Bioinformatics; Biology; Computer science; Receptor; Internal medicine","score_opus":0.2418730811449664,"score_gpt":0.46760138806402873,"score_spread":0.22572830691906234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017631478","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0065328986,0.99199814,0.00003019561,0.00006316876,0.00020017939,0.00040624966,0.000019605965,0.0000064649203,0.0007431182],"genre_scores_gemma":[0.0038926315,0.9950742,0.00054559176,0.000088258144,0.00008624003,0.00017944344,0.00006522892,0.000007052159,0.00006131973],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99586594,0.0020472917,0.000688221,0.00061721815,0.00036353292,0.00041777844],"domain_scores_gemma":[0.99906665,0.00034157067,0.00039739354,0.00013034901,0.000025250163,0.00003880118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021146585,0.00030769114,0.000971418,0.00016327831,0.00010982862,0.00005226898,0.0010244048,0.00031993826,0.00022739547],"category_scores_gemma":[0.00028798977,0.00015338628,0.00030435098,0.0012000581,0.0005962941,0.000027885055,0.00018659745,0.00036575843,0.0000012474445],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022287131,0.0003045615,0.000013033542,0.000092767485,0.000020809524,0.000016115293,0.000027647833,0.000040397794,0.0043244674,0.00020010088,0.00014348727,0.9947943],"study_design_scores_gemma":[0.00039931192,0.0010461481,0.000046425434,0.001036364,0.00006305037,0.000023307071,0.00015753694,0.000015814616,0.004008262,0.0005513167,0.9922187,0.0004337721],"about_ca_topic_score_codex":0.000008592157,"about_ca_topic_score_gemma":0.000028287706,"teacher_disagreement_score":0.99436057,"about_ca_system_score_codex":0.000036623056,"about_ca_system_score_gemma":0.00009816084,"threshold_uncertainty_score":0.6254911},"labels":[],"label_agreement":null},{"id":"W2017697164","doi":"10.1152/ajpcell.00337.2013","title":"Enhanced expression of G<sub>q</sub>α and PLC-β1 proteins contributes to vascular smooth muscle cell hypertrophy in SHR: role of endogenous angiotensin II and endothelin-1","year":2014,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Vascular smooth muscle; Internal medicine; Endocrinology; Endothelin 1; Angiotensin II; Muscle hypertrophy; Endothelin receptor; Losartan; Receptor; Endogeny; Gq alpha subunit; Signal transduction; Chemistry; Biology; G protein; Medicine; Cell biology","score_opus":0.003425764156158879,"score_gpt":0.1792703958613122,"score_spread":0.1758446317051533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017697164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99726605,0.0014420545,0.000908658,0.000028113582,0.00006723447,0.00024315163,0.000015094047,0.0000033800536,0.000026256253],"genre_scores_gemma":[0.99674857,0.0006430302,0.0022489342,0.00017072425,0.00013615852,0.000011036593,0.000010074075,0.000029381494,0.00000209733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815863,0.00036346607,0.0006138667,0.00040492543,0.00010988795,0.00034919404],"domain_scores_gemma":[0.9985323,0.00008658641,0.0007433077,0.0002917741,0.00022165693,0.00012437672],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002977628,0.0002567618,0.0009176276,0.00016166491,0.00006629909,0.0000041616236,0.0002250244,0.00014912129,0.0000059830304],"category_scores_gemma":[0.000083550505,0.00021438819,0.00018205964,0.00013736803,0.00037408352,0.000009359554,0.00020700594,0.0001880567,6.6286606e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055284257,0.00023617827,0.000028248169,0.000038421436,0.000042080625,6.921439e-7,0.0002845367,0.00061847357,0.9936557,0.0000131329625,0.000009841062,0.0045198547],"study_design_scores_gemma":[0.001442352,0.005006683,0.002361086,0.000059108697,0.000034866094,0.0000047078984,0.0003915441,0.00005583876,0.98960626,0.0005409997,0.00030366317,0.00019286275],"about_ca_topic_score_codex":0.000051295912,"about_ca_topic_score_gemma":0.000003624553,"teacher_disagreement_score":0.004770505,"about_ca_system_score_codex":0.000011236062,"about_ca_system_score_gemma":0.0000628597,"threshold_uncertainty_score":0.87424964},"labels":[],"label_agreement":null},{"id":"W2017920342","doi":"10.1139/y08-048","title":"Nonpeptidic antagonists of ET<sub>A</sub>and ET<sub>B</sub>receptors reverse the ET-1-induced sustained increase of cytosolic and nuclear calcium in human aortic vascular smooth muscle cellsThis article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin.","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Pertussis toxin; Protein kinase C; Chemistry; Calcium; Vascular smooth muscle; Endocrinology; Internal medicine; Receptor; G protein; Biochemistry; Biology; Signal transduction; Medicine","score_opus":0.01079865586363939,"score_gpt":0.24016946546302245,"score_spread":0.22937080959938305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017920342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991795,0.00014921826,0.0000019302288,0.00030539505,0.00009583184,0.0002056708,0.000018400402,5.018548e-7,0.00004358052],"genre_scores_gemma":[0.99846625,0.0008545308,0.000016698017,0.0005277414,0.00011196692,0.0000038060437,0.000005686267,0.000011954712,0.0000013463508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99832606,0.00063179305,0.00055256224,0.0001786774,0.00009090708,0.00021999028],"domain_scores_gemma":[0.9991892,0.000077237004,0.0004145085,0.00010202706,0.000114517585,0.000102482474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081452675,0.00013290536,0.00042291064,0.00022104206,0.000053845146,0.000003103806,0.0001350131,0.0001710682,0.00020142036],"category_scores_gemma":[0.000069213194,0.00010622995,0.000081793565,0.00017297128,0.00034307258,0.000020230864,0.000027144446,0.00028712876,9.4640576e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041815752,0.00014243755,0.0015019953,0.000077340075,0.00007454228,0.0000075569615,0.0028739676,0.0000677086,0.99417216,0.000060214585,0.0002449461,0.0003590041],"study_design_scores_gemma":[0.0019185727,0.0011323303,0.018670436,0.00004328168,0.000047602225,0.0000109847715,0.00070359255,0.00004269371,0.97695035,0.0001435926,0.00025194485,0.00008464454],"about_ca_topic_score_codex":0.0019892124,"about_ca_topic_score_gemma":0.003964282,"teacher_disagreement_score":0.017221807,"about_ca_system_score_codex":0.00002492721,"about_ca_system_score_gemma":0.00031810056,"threshold_uncertainty_score":0.43319318},"labels":[],"label_agreement":null},{"id":"W2018053021","doi":"10.1016/j.bcp.2004.11.020","title":"β-Adrenergic receptor modulation of the LPS-mediated depression in CYP1A activity in astrocytes","year":2005,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Downregulation and upregulation; Clenbuterol; Receptor; Endocrinology; Internal medicine; Agonist; Stimulation; Forskolin; Adrenergic receptor; Chemistry; Biology; Medicine; Biochemistry","score_opus":0.008505864615669911,"score_gpt":0.260578643136595,"score_spread":0.2520727785209251,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018053021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986491,0.000547396,0.00014729104,0.00019706757,0.00019903065,0.00017691699,0.000008879716,0.00000580024,0.0000684833],"genre_scores_gemma":[0.99904275,0.00008829498,0.00038732195,0.00014498793,0.00021474308,0.000028384353,0.00003720242,0.000011999007,0.00004431919],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990414,0.00012470038,0.00023765097,0.0002787494,0.00009863944,0.00021885437],"domain_scores_gemma":[0.9996572,0.00002727319,0.000105092906,0.00013326172,0.00003119078,0.000045940305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016347053,0.00012176666,0.00015652843,0.000052856074,0.000021376136,0.000003020475,0.00019267622,0.00023483878,0.00021637659],"category_scores_gemma":[0.000053270385,0.00009762469,0.00006734494,0.00015782224,0.00006165801,0.0000054603834,0.00012631026,0.00015773278,0.0000038374824],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022576403,0.00014627888,0.0027583214,0.000007890003,0.000008938014,2.8770052e-7,0.000017475555,0.0011242523,0.9928019,0.0000037522263,0.0021323492,0.00077280053],"study_design_scores_gemma":[0.00099404,0.000042762054,0.006082047,0.000013397517,0.0000053765752,0.000001211324,0.0000070057963,0.0023932955,0.9887999,0.00000858527,0.0015520506,0.00010032264],"about_ca_topic_score_codex":0.000020123212,"about_ca_topic_score_gemma":0.000008216739,"teacher_disagreement_score":0.004001985,"about_ca_system_score_codex":0.0000435129,"about_ca_system_score_gemma":0.000045000572,"threshold_uncertainty_score":0.39810193},"labels":[],"label_agreement":null},{"id":"W2018151046","doi":"10.1139/y04-039","title":"An indomethacin-sensitive contraction induced by β-antagonists in guinea pig airways","year":2004,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pindolol; Bronchoconstriction; Atenolol; Antagonist; Propranolol; Agonist; Contraction (grammar); Internal medicine; Chemistry; Endocrinology; Pharmacology; Population; Receptor antagonist; Receptor; Medicine; Asthma","score_opus":0.009461338370850069,"score_gpt":0.2676903420580257,"score_spread":0.25822900368717566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018151046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99821913,0.00042470175,0.00027776932,0.0003132854,0.0006098215,0.00008728186,0.000021449627,0.0000014823298,0.00004506041],"genre_scores_gemma":[0.9982821,0.00015050925,0.00012818133,0.0010220534,0.00035239366,0.000003032502,0.000038390604,0.000011306997,0.0000120546265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999062,0.00018128379,0.00025446844,0.00018744754,0.000036381673,0.00027839176],"domain_scores_gemma":[0.99933434,0.000018832134,0.00015959296,0.00006446376,0.00010589332,0.00031687669],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027098652,0.0001265258,0.000235003,0.00013913265,0.00009390864,0.000008804692,0.00011188766,0.0002429298,0.00020161422],"category_scores_gemma":[0.000022045178,0.00012254086,0.00004818166,0.000066387474,0.00010765459,0.000014598156,0.000008496133,0.00028979298,0.0000018192744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018323101,0.000035228455,0.00013664993,0.0000059305976,0.00004917253,0.000030737392,0.00013633717,0.00024265563,0.99821496,0.00007715362,0.0003114075,0.00057652575],"study_design_scores_gemma":[0.001876315,0.0010896744,0.00084208045,0.000005847205,0.000019557876,0.00010374763,0.00012011963,0.000010171352,0.99266773,0.0004677891,0.0026696504,0.00012728259],"about_ca_topic_score_codex":0.0008921372,"about_ca_topic_score_gemma":0.0015512616,"teacher_disagreement_score":0.005547206,"about_ca_system_score_codex":0.000046834866,"about_ca_system_score_gemma":0.0004546624,"threshold_uncertainty_score":0.49970716},"labels":[],"label_agreement":null},{"id":"W201847332","doi":"10.1016/b978-0-12-394440-5.00004-8","title":"Arrestins","year":2013,"lang":"en","type":"review","venue":"Progress in molecular biology and translational science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Cell biology; Function (biology); Biology; Desensitization (medicine); Scaffold protein; Intracellular; Receptor; Computational biology; Signal transduction; Biochemistry","score_opus":0.023402607408312223,"score_gpt":0.3624054372226567,"score_spread":0.3390028298143445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W201847332","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00071947434,0.994541,0.0039732475,0.000024266144,0.00013019865,0.00039920898,0.000014662986,0.000006844939,0.00019111829],"genre_scores_gemma":[0.004127267,0.9865386,0.008868604,0.000030410667,0.000073831005,0.00016892553,0.00015672472,0.000018475721,0.00001718343],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99850106,0.0000989106,0.0002968772,0.00064875314,0.0001307029,0.00032371422],"domain_scores_gemma":[0.99955463,0.0000183057,0.00010119131,0.00018449906,0.000051387917,0.00009000758],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043092508,0.00024019837,0.00038192683,0.00016339854,0.000111495945,0.00004337928,0.0003480303,0.00031542373,0.00003259188],"category_scores_gemma":[0.000024514797,0.00019103964,0.00010745162,0.00029057823,0.0007799482,0.0000062524878,0.00008741585,0.00017983526,0.0000066011294],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000029934304,0.000026348418,0.00048513027,0.00032708998,0.000024102595,0.0000044725107,0.000007744706,0.000001967132,0.0025064603,0.011076061,0.000002506733,0.98553514],"study_design_scores_gemma":[0.00042610068,0.00024137838,0.00015453328,0.0014186843,0.000110076864,0.00010779276,0.0000074022428,0.00008815544,0.0034490717,0.0061172056,0.9869309,0.00094868004],"about_ca_topic_score_codex":0.000002714704,"about_ca_topic_score_gemma":0.0000021781032,"teacher_disagreement_score":0.9869284,"about_ca_system_score_codex":0.0000061572055,"about_ca_system_score_gemma":0.00026925074,"threshold_uncertainty_score":0.779037},"labels":[],"label_agreement":null},{"id":"W2018626017","doi":"10.1016/j.bmc.2014.06.011","title":"Synthesis and evaluation of the novel 2-[18F]fluoro-3-propoxy-triazole-pyridine-substituted losartan for imaging AT1 receptors","year":2014,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Ottawa","funders":"Ontario Partnership for Innovation and Commercialization; Canadian Institutes of Health Research; University of Ottawa; Heart and Stroke Foundation of Canada","keywords":"Chemistry; Losartan; Tetrazole; Biodistribution; Azide; Candesartan; Triazole; Angiotensin II receptor type 1; Angiotensin II; Angiotensin receptor; Kidney; Receptor; Pharmacology; Positron emission tomography; Stereochemistry; Internal medicine; Biochemistry; Nuclear medicine; In vitro; Organic chemistry","score_opus":0.016197112099302677,"score_gpt":0.2499799654572016,"score_spread":0.23378285335789895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018626017","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993993,0.0010304133,0.0035402244,0.00039016735,0.00038085703,0.00033606053,0.000023115015,0.000013301944,0.00029289778],"genre_scores_gemma":[0.9985297,0.000049673963,0.0005466514,0.000077610894,0.00060701213,0.000042929107,0.000050468505,0.00003179338,0.000064210166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985425,0.00005499928,0.00033745408,0.0004105395,0.0004087161,0.0002457859],"domain_scores_gemma":[0.9989131,0.00006339688,0.00023131285,0.0003932421,0.00029713896,0.000101816186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012865294,0.00021239402,0.00023985826,0.00001558604,0.00013905785,0.000016324186,0.00027184933,0.00014293645,0.00017494822],"category_scores_gemma":[0.0013704882,0.00016080729,0.000112710826,0.00011126151,0.00016217044,0.0000059406075,0.00009130953,0.00010340093,9.3067854e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000083553874,0.000032665164,0.00032133446,0.00009433872,0.000045755816,8.489015e-8,0.000030903506,0.0000089134755,0.9946763,0.000032564098,0.00037098114,0.0043026395],"study_design_scores_gemma":[0.0010125679,0.00004869861,0.00020072637,0.000115745854,0.00022777241,0.000020915846,0.00021529703,0.0022083197,0.9923138,0.00008651359,0.0033627334,0.00018690462],"about_ca_topic_score_codex":0.000014470338,"about_ca_topic_score_gemma":0.0000029601283,"teacher_disagreement_score":0.004536688,"about_ca_system_score_codex":0.000040117968,"about_ca_system_score_gemma":0.00017073732,"threshold_uncertainty_score":0.65575314},"labels":[],"label_agreement":null},{"id":"W2019074781","doi":"10.1038/nrd913","title":"G-Protein-coupled receptor oligomerization and its potential for drug discovery","year":2002,"lang":"en","type":"review","venue":"Nature Reviews Drug Discovery","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":588,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Drug discovery; Computational biology; Receptor; Drug design; Drug development; Drug; Biology; Chemistry; Pharmacology; Bioinformatics; Biochemistry","score_opus":0.01484033711655092,"score_gpt":0.2833211184961046,"score_spread":0.26848078137955367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019074781","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00035511886,0.990734,0.0025627778,0.00004687138,0.0012958491,0.004408791,0.00051048194,0.000023464318,0.000062655316],"genre_scores_gemma":[0.00018025476,0.98047,0.0007283944,0.00015151096,0.0021387849,0.00089567585,0.003589397,0.00019170389,0.011654259],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961599,0.00036627278,0.0011808042,0.001381672,0.00032791297,0.0005834329],"domain_scores_gemma":[0.9979902,0.000046401172,0.0009887585,0.0006905652,0.00011825625,0.00016582909],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007582341,0.0010087861,0.0023511318,0.00015813462,0.00023054006,0.0003743556,0.00055102777,0.0011934758,0.000076949415],"category_scores_gemma":[0.0003375149,0.00076467695,0.0014819069,0.0002860584,0.00005230348,0.00007967885,0.00026631742,0.0007797408,0.00003470286],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011133827,0.00025538704,4.3197988e-7,0.06374841,0.00078972033,0.000008325115,0.00005410318,0.0000107360465,0.05587025,0.0019108073,0.019360617,0.8578799],"study_design_scores_gemma":[0.00035801964,0.00006927492,6.533364e-8,0.008253274,0.00066518714,0.000020097883,0.000010186687,0.0000415749,0.0027550957,0.000038258586,0.98688704,0.0009019384],"about_ca_topic_score_codex":0.0000033199315,"about_ca_topic_score_gemma":0.0000044632748,"teacher_disagreement_score":0.96752644,"about_ca_system_score_codex":0.000067219786,"about_ca_system_score_gemma":0.00018096322,"threshold_uncertainty_score":0.9994804},"labels":[],"label_agreement":null},{"id":"W2019167264","doi":"10.1523/jneurosci.4653-03.2004","title":"Magnitude of Dopamine Release in Medial Prefrontal Cortex Predicts Accuracy of Memory on a Delayed Response Task","year":2004,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Prefrontal cortex; Recall; Neuroscience; Psychology; Dopamine; Task (project management); Cognition; Working memory; Cognitive psychology","score_opus":0.011522975963329019,"score_gpt":0.25839761660526794,"score_spread":0.24687464064193892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019167264","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982571,0.00013221145,0.0010768982,0.00007257197,0.00033768534,0.0000882777,0.000011742756,0.0000013013672,0.00002220261],"genre_scores_gemma":[0.9990673,0.00015182258,0.0005355379,0.0001275922,0.00007437082,0.00000104366,0.0000010226984,0.000008173035,0.000033129098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873674,0.00010254512,0.00047113345,0.00016952101,0.00036858284,0.00015145687],"domain_scores_gemma":[0.9990973,0.00004892796,0.0004757239,0.0001579485,0.00012257414,0.00009756182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005615751,0.00009594585,0.00018795484,0.00012391932,0.000023325823,0.0000076097804,0.0003039141,0.00006222715,0.000005917908],"category_scores_gemma":[0.0014897904,0.00007884565,0.00008739955,0.0001497152,0.000116699324,0.000015117508,0.000057680012,0.00014301714,2.979571e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026867606,0.00019317094,0.000092118535,0.000008133126,0.0000029275993,0.000058233996,0.00008290538,0.0027540133,0.99351543,0.0000052140313,0.000015463076,0.0005856247],"study_design_scores_gemma":[0.0015053918,0.0044824216,0.020586392,0.00007768096,0.000009334174,0.00013186553,0.000052860785,0.00010310754,0.97277373,0.000034811765,0.00016953789,0.00007288808],"about_ca_topic_score_codex":0.000011677446,"about_ca_topic_score_gemma":0.0000075696685,"teacher_disagreement_score":0.020741725,"about_ca_system_score_codex":0.000020109845,"about_ca_system_score_gemma":0.00030717588,"threshold_uncertainty_score":0.32152325},"labels":[],"label_agreement":null},{"id":"W2019654400","doi":"10.1016/s0014-5793(00)01315-6","title":"Distinct function of the cytoplasmic tail in human D1‐like receptor ligand binding and coupling","year":2000,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Biophysics; Cytoplasm; Coupling (piping); Function (biology); Chemistry; Ligand (biochemistry); Receptor; Cell biology; Biology; Biochemistry; Materials science","score_opus":0.006629962450594818,"score_gpt":0.2035820205887992,"score_spread":0.19695205813820438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019654400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991886,0.000101540216,0.0001696625,0.00018332974,0.0001614545,0.00009795603,0.000005470984,0.0000048511192,0.000087142325],"genre_scores_gemma":[0.9991633,0.00002986008,0.00006822008,0.00031289257,0.00010340184,0.0000060737475,0.000025050054,0.000013051039,0.00027813105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994012,0.00002032915,0.00015822954,0.000197353,0.00008034499,0.00014250816],"domain_scores_gemma":[0.9997627,0.000006993144,0.000055649747,0.00014081011,0.000009326024,0.000024507226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013842045,0.00009352315,0.00009736133,0.000027681164,0.00009622721,0.000017583749,0.000086666136,0.00006922062,0.00010069732],"category_scores_gemma":[0.000008003617,0.00007512369,0.000046156354,0.00007030928,0.000046639474,0.000004030149,0.00003125141,0.00008146529,0.0000030716758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032205717,0.000009421803,0.0075847846,0.000010884944,0.000010777307,4.1151085e-7,0.000043746215,0.00023809665,0.99094385,0.00001006621,0.00042347072,0.0006922687],"study_design_scores_gemma":[0.00052190485,0.00009959038,0.0056284596,0.00006378668,0.00001415479,0.000003101795,0.00006529486,0.00013501645,0.98688644,0.000018991765,0.0064086127,0.00015464144],"about_ca_topic_score_codex":0.000026474589,"about_ca_topic_score_gemma":0.000025307609,"teacher_disagreement_score":0.005985142,"about_ca_system_score_codex":0.000011620837,"about_ca_system_score_gemma":0.00000857623,"threshold_uncertainty_score":0.30634552},"labels":[],"label_agreement":null},{"id":"W2019734528","doi":"10.1371/journal.pone.0043766","title":"Engineering of an Artificial Light-Modulated Potassium Channel","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Indian Council for Cultural Relations; University of Toronto; Agence Nationale de la Recherche","keywords":"Rhodopsin; Opsin; G protein-coupled receptor; Retinal; Biophysics; Biology; Cell biology; Ligand-gated ion channel; Voltage clamp; Potassium channel; Receptor; Xenopus; Chemistry; Biochemistry; Ion channel; Membrane potential","score_opus":0.02538128326773719,"score_gpt":0.20939909784949062,"score_spread":0.18401781458175342,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019734528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985141,0.00020771775,0.00093978836,0.000024900177,0.00009310165,0.00007553198,0.0000061148394,0.000014023512,0.00012473477],"genre_scores_gemma":[0.9971255,0.000010866145,0.0021556655,0.000020647876,0.0005361963,0.0000071922946,0.00004986115,0.000019802514,0.00007424544],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994161,0.00001529927,0.00013576855,0.00012282954,0.00010983107,0.0002001667],"domain_scores_gemma":[0.99964696,0.000002404649,0.000043392236,0.00017173139,0.00004678994,0.00008869961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012567929,0.000083840096,0.00011928643,0.000029670331,0.000023352628,0.0000065882696,0.00007836936,0.00010271426,0.00006975348],"category_scores_gemma":[0.000029824385,0.00008338206,0.000036755955,0.000046867233,0.000006664379,0.000005345615,0.000031161395,0.00004691299,0.000009207313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018033994,0.00043779577,0.00004460899,0.00002248662,0.00006761358,2.5898316e-7,0.00007334315,0.000072376206,0.9990518,0.00008261695,0.000009792969,0.00011925372],"study_design_scores_gemma":[0.00008455558,0.00013115769,0.00011179727,0.00001979914,0.000027612397,8.9640264e-7,0.00002429011,0.0013837352,0.9979914,0.000023893086,0.000095099946,0.00010578104],"about_ca_topic_score_codex":0.0000043220352,"about_ca_topic_score_gemma":8.379375e-7,"teacher_disagreement_score":0.0013885642,"about_ca_system_score_codex":0.0000044422877,"about_ca_system_score_gemma":0.000008857722,"threshold_uncertainty_score":0.34002215},"labels":[],"label_agreement":null},{"id":"W2020060900","doi":"10.1016/j.mce.2003.10.066","title":"Forskolin-resistant Y1 adrenal cell mutants are deficient in adenylyl cyclase type 4","year":2003,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; University of Toronto","funders":"","keywords":"Forskolin; Adenylyl cyclase; ADCY10; Mutant; ADCY9; Cell culture; Transfection; Biology; Molecular biology; Activator (genetics); Gene isoform; Internal medicine; Endocrinology; Cell biology; Signal transduction; Chemistry; Gene; Biochemistry; Genetics; Medicine","score_opus":0.007836127791083211,"score_gpt":0.21283532308741443,"score_spread":0.2049991952963312,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020060900","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9838369,0.00906628,0.0048847925,0.000035183915,0.00025248574,0.00020331336,0.000009969822,0.000013902521,0.001697186],"genre_scores_gemma":[0.998294,0.0002673839,0.0007379709,0.00023757714,0.000035454923,0.000019460234,0.00005080463,0.000038970134,0.0003184048],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814695,0.00018158203,0.00030633973,0.00059550075,0.00014630698,0.0006233068],"domain_scores_gemma":[0.99934465,0.00000985721,0.000096388416,0.00035116996,0.00006169836,0.00013625385],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014050119,0.00026894102,0.00027538862,0.000116429066,0.000087630186,0.00002774586,0.00016051526,0.00020177456,0.00011834888],"category_scores_gemma":[0.00006255468,0.00026858834,0.00010308232,0.00014744062,0.00007831563,0.0000037303278,0.00009759029,0.00019256101,0.000018050965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095331125,0.00011038903,0.0007586098,0.000025085037,0.000023464581,0.00050469226,0.00002976132,0.00016227852,0.9957722,0.0022068252,0.000054824697,0.00025656927],"study_design_scores_gemma":[0.0010773191,0.00035446638,0.00009896789,0.000014258738,0.00002461957,0.000100273974,0.00022298646,0.00005722395,0.9847605,0.0004598393,0.012517669,0.00031183477],"about_ca_topic_score_codex":0.000023613811,"about_ca_topic_score_gemma":0.000030959967,"teacher_disagreement_score":0.014457087,"about_ca_system_score_codex":0.000019624062,"about_ca_system_score_gemma":0.00006650884,"threshold_uncertainty_score":0.99997663},"labels":[],"label_agreement":null},{"id":"W2020098668","doi":"10.1016/j.brainres.2004.06.073","title":"Regulators of G-protein signaling 4: modulation of 5-HT1A-mediated neurotransmitter release in vivo","year":2004,"lang":"en","type":"article","venue":"Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Microdialysis; Autoreceptor; Dorsal raphe nucleus; G protein-coupled receptor; Biology; Receptor; Serotonin; In vivo; G protein; Signal transduction; Neurotransmitter; Pharmacology; 5-HT receptor; Internal medicine; Cell biology; Endocrinology; Serotonergic; Extracellular; Biochemistry; Medicine","score_opus":0.02784603759737219,"score_gpt":0.3057188365440035,"score_spread":0.2778727989466313,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020098668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99692875,0.00016572724,0.0021510622,0.0002804971,0.000021687509,0.0003235508,0.000009693422,0.00000415673,0.00011485698],"genre_scores_gemma":[0.9987924,0.000020979136,0.0009186929,0.000035128356,0.00005152275,0.000019017862,0.000020742491,0.000020890571,0.000120595076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985519,0.00020768693,0.00031902458,0.00026885854,0.00038419696,0.00026834855],"domain_scores_gemma":[0.999386,0.000045796718,0.00006537505,0.00025598326,0.00018230232,0.0000645471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010443596,0.00009011054,0.00014845384,0.00020104405,0.000034910405,0.0000078278745,0.00017556357,0.00014955614,0.000097109194],"category_scores_gemma":[0.0003595676,0.00008894869,0.00006897943,0.0003454498,0.000097069504,0.000005189219,0.00005443729,0.0001602412,0.0000021819515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012732252,0.00006616985,0.00038688863,0.00006842801,0.000009345301,0.0000043272353,0.00012437439,0.004413627,0.99391305,0.0003743759,0.00003060264,0.00048147675],"study_design_scores_gemma":[0.00076071225,0.00029358847,0.00091762916,0.00010929645,0.0000011386475,0.0000010510748,0.0000767009,0.00040463518,0.99584836,0.0011911863,0.00031296434,0.00008274662],"about_ca_topic_score_codex":0.00016849683,"about_ca_topic_score_gemma":0.000024551091,"teacher_disagreement_score":0.0040089916,"about_ca_system_score_codex":0.000018307448,"about_ca_system_score_gemma":0.00012317149,"threshold_uncertainty_score":0.36272225},"labels":[],"label_agreement":null},{"id":"W2020275122","doi":"10.1038/nature10798","title":"Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human","year":2012,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":659,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Japan Science and Technology Agency; Medical Research Council; Council for Science and Technology Policy; Oulun Yliopisto; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Agence Nationale de la Recherche; European Commission","keywords":"GPR120; Endocrinology; Adipose tissue; Internal medicine; Lipogenesis; Biology; Receptor; Insulin receptor; Adipogenesis; Free fatty acid receptor 1; Nutrient sensing; Energy homeostasis; Insulin resistance; Glucose homeostasis; Insulin; Obesity; Cell biology; Signal transduction; Medicine; G protein-coupled receptor","score_opus":0.006691838515754685,"score_gpt":0.24622647111847046,"score_spread":0.23953463260271576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020275122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99883056,0.00050892093,0.00015394586,0.000036597736,0.00013398951,0.00007851464,0.0000052651367,0.000003973861,0.00024825995],"genre_scores_gemma":[0.9983673,0.000019679195,0.00054196024,0.00022786,0.00026305392,0.0000024890228,0.000019701914,0.000008434306,0.0005495224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995836,0.000022655053,0.00008165975,0.00012289875,0.00006330211,0.00012586181],"domain_scores_gemma":[0.9997881,0.0000028521085,0.000027100683,0.00010466715,0.000024062629,0.00005322499],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013791652,0.00006747236,0.000084231164,0.000031826952,0.00002571937,0.0000047804897,0.000041698626,0.00048348904,0.000029051836],"category_scores_gemma":[0.000024885612,0.00006076946,0.000024581312,0.00004543967,0.000009713413,0.0000031440482,0.000036028483,0.00023886134,0.0000015082578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021455387,0.000034051718,0.029792538,0.000012014533,0.0000043738532,1.5927128e-7,0.000055681503,0.0000071499117,0.9691149,0.00021017401,0.0005806265,0.00016690054],"study_design_scores_gemma":[0.00020552355,0.0001190695,0.022580717,0.000008210194,0.000003843451,0.00000216102,0.000040102903,0.0000021827989,0.9681867,0.000010626092,0.008759132,0.00008178263],"about_ca_topic_score_codex":0.000012238292,"about_ca_topic_score_gemma":0.000022482827,"teacher_disagreement_score":0.008178505,"about_ca_system_score_codex":0.000006669574,"about_ca_system_score_gemma":0.0000059055897,"threshold_uncertainty_score":0.37291104},"labels":[],"label_agreement":null},{"id":"W2020348358","doi":"10.1016/j.cellsig.2008.08.013","title":"Membrane signalling complexes: Implications for development of functionally selective ligands modulating heptahelical receptor signalling","year":2008,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Louis-H Lafontaine; Université de Montréal","funders":"","keywords":"Signalling; G protein-coupled receptor; Functional selectivity; Receptor; Cell biology; Effector; Signal transduction; Biology; Chemistry; Biochemistry","score_opus":0.057074324978881395,"score_gpt":0.2986460385664156,"score_spread":0.24157171358753418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020348358","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0016998481,0.5834723,0.4129623,0.000007592413,0.00024298868,0.0013829794,0.00011724808,0.00005254074,0.00006218826],"genre_scores_gemma":[0.011423977,0.8986921,0.08073604,0.00004237693,0.0017185494,0.000847595,0.005827958,0.00039972694,0.00031171378],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9946271,0.00016939663,0.002320744,0.001522108,0.00048070095,0.00087990967],"domain_scores_gemma":[0.99663305,0.0003851649,0.0014000285,0.00048749472,0.0007991599,0.00029511403],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00085444306,0.0010530058,0.002140358,0.0003456393,0.00085860403,0.00008186403,0.00079634105,0.0010032896,0.00009946184],"category_scores_gemma":[0.00018025932,0.0010497342,0.0014604676,0.0005084708,0.00012223542,0.000018650246,0.00021470735,0.0005658671,0.000018546809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005851416,0.00015481179,0.0000020798843,0.0034677372,0.000964483,0.0000013683473,0.00016821038,0.0032270714,0.8869809,0.00022337482,0.00013205112,0.1046194],"study_design_scores_gemma":[0.0005359368,0.000285906,3.0490497e-7,0.0038881418,0.00043767763,0.000028432974,0.00005154997,0.0007870951,0.6283976,0.00010754586,0.36423045,0.0012493627],"about_ca_topic_score_codex":0.0000048776737,"about_ca_topic_score_gemma":0.0000040252457,"teacher_disagreement_score":0.3640984,"about_ca_system_score_codex":0.00017592464,"about_ca_system_score_gemma":0.0013660139,"threshold_uncertainty_score":0.9991953},"labels":[],"label_agreement":null},{"id":"W2020695556","doi":"10.1124/mol.104.009068","title":"Identification of a Potent and Selective Synthetic Agonist at the CRTH2 Receptor","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"TransCanada (Canada)","funders":"","keywords":"Agonist; Identification (biology); Receptor; Computational biology; Chemistry; Pharmacology; Biology; Biochemistry","score_opus":0.005190862373438755,"score_gpt":0.2524764625936925,"score_spread":0.24728560022025375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020695556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896169,0.0019326806,0.006387542,0.0011978827,0.00017290754,0.0003956616,0.000015520518,0.000008208235,0.00027272356],"genre_scores_gemma":[0.99813855,0.00021829126,0.00025298892,0.0005819829,0.00011995861,0.000082710954,0.000026474092,0.000019103925,0.0005599485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990318,0.00015611503,0.00023052238,0.00029831255,0.00009868938,0.0001845748],"domain_scores_gemma":[0.9995429,0.000014831042,0.00013239427,0.00017184237,0.00008591941,0.000052114647],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002536264,0.000121155994,0.0001221745,0.000030633055,0.00012188851,0.000011473295,0.00014102814,0.00009985348,0.00017672729],"category_scores_gemma":[0.000025389438,0.00009873888,0.00007447978,0.000066544104,0.00014010924,0.0000027587319,0.00012182521,0.00007888337,0.000017620358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081466875,0.000047511065,0.00002382916,0.000008822893,0.000081442966,0.000001266071,0.000068741094,0.00034105137,0.9921567,0.000114887276,0.0017044004,0.0053699226],"study_design_scores_gemma":[0.00037449077,0.0001319534,0.000052026735,0.0000030817187,0.000052375373,0.000024624162,0.000028533126,0.00034404494,0.9703827,0.00003883573,0.028463893,0.00010344871],"about_ca_topic_score_codex":0.000005121982,"about_ca_topic_score_gemma":0.0000052446694,"teacher_disagreement_score":0.026759492,"about_ca_system_score_codex":0.00002668894,"about_ca_system_score_gemma":0.000033115706,"threshold_uncertainty_score":0.40264547},"labels":[],"label_agreement":null},{"id":"W2020762809","doi":"10.1016/j.neuropharm.2009.07.010","title":"The relation between open-field and emergence tests in a hyperactive mouse model","year":2009,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital Saint-Luc","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Open field; Cohort; Correlation; Association (psychology); Medicine; Psychology; Developmental psychology; Audiology; Physiology; Biology; Internal medicine; Mathematics","score_opus":0.02195592767381327,"score_gpt":0.32297160357309546,"score_spread":0.3010156758992822,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020762809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99756336,0.00015741131,0.00065908337,0.0008292693,0.00008771639,0.00019629403,0.0000023664468,0.000004867034,0.0004996246],"genre_scores_gemma":[0.9975022,0.00056946714,0.00026585083,0.0012362337,0.00007856148,0.000012933551,0.000004417416,0.000007853234,0.00032249457],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993331,0.0000917504,0.00013806477,0.00023284642,0.00004535483,0.00015888536],"domain_scores_gemma":[0.9997171,0.00006203587,0.000048545488,0.0001030081,0.000026771168,0.000042503292],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013986492,0.00008179269,0.000086214146,0.000020084473,0.00010862018,0.000022800341,0.00018675782,0.00007994417,0.000014225512],"category_scores_gemma":[0.00008780095,0.000066440516,0.000017265706,0.000050688202,0.00001865983,0.000007756595,0.00009580322,0.00014227,0.0000022380405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000090978574,0.000018314828,0.0007431907,6.951294e-7,0.000005325887,0.0000023222558,0.000028617336,0.0005512812,0.99210584,0.00017486082,0.00034034057,0.005938204],"study_design_scores_gemma":[0.0007915763,0.0007224696,0.009360369,0.0000025014047,0.00001496946,0.0000053509903,0.000024196499,0.005037916,0.98063505,0.0008776074,0.0023770374,0.00015096106],"about_ca_topic_score_codex":0.000008793236,"about_ca_topic_score_gemma":0.00000833209,"teacher_disagreement_score":0.0114708245,"about_ca_system_score_codex":0.0000045018674,"about_ca_system_score_gemma":0.000027547134,"threshold_uncertainty_score":0.27093658},"labels":[],"label_agreement":null},{"id":"W2021057279","doi":"10.1016/s0014-5793(01)02513-3","title":"Primary sequence requirements for <i>S</i>‐acylation of β<sub>2</sub>‐adrenergic receptor peptides","year":2001,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Medical Research Council","keywords":"Palmitoylation; Acylation; Chemistry; Cysteine; Sequence (biology); Biochemistry; In vivo; Peptide sequence; Receptor; Stereochemistry; Biology; Enzyme; Gene; Genetics","score_opus":0.021978990366996073,"score_gpt":0.2474564926546918,"score_spread":0.22547750228769572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021057279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98377806,0.0001483266,0.015089691,0.00031003257,0.00025742754,0.00023069869,0.000023806318,0.000013393482,0.00014857287],"genre_scores_gemma":[0.9932045,0.0002037092,0.0040203216,0.0016851967,0.00031910988,0.000042348678,0.00042997065,0.00002783937,0.00006703829],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990451,0.000032727577,0.00025099207,0.00029252077,0.00014908244,0.00022960462],"domain_scores_gemma":[0.99950117,0.000013219733,0.00014927419,0.00021649587,0.00006929913,0.000050560444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018976018,0.00013892648,0.00014652837,0.000042335385,0.00006733786,0.000015455375,0.00014560879,0.00009176153,0.000018281917],"category_scores_gemma":[0.00003214208,0.0001401342,0.00011866488,0.00007615523,0.00004415927,0.000010456897,0.000040318093,0.000042801847,0.000005338902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012719654,0.000022163034,0.00049826916,0.000031367937,0.00003284409,8.984998e-7,0.000023825995,0.00028507275,0.9924789,0.000039521496,0.002855384,0.0036045245],"study_design_scores_gemma":[0.00043636252,0.0001937522,0.0002008404,0.000032012296,0.000015298747,0.0000039682063,0.000015174682,0.00004326553,0.9895237,0.00006462311,0.009307203,0.00016377891],"about_ca_topic_score_codex":0.000006753877,"about_ca_topic_score_gemma":0.0000031281027,"teacher_disagreement_score":0.011069369,"about_ca_system_score_codex":0.000028395723,"about_ca_system_score_gemma":0.00003064202,"threshold_uncertainty_score":0.57145065},"labels":[],"label_agreement":null},{"id":"W2022108999","doi":"10.1016/j.psychres.2003.12.002","title":"Alpha 2A adrenergic receptor gene and suicide","year":2004,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Louis-H Lafontaine; Université de Montréal; McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Allele; Genetics; Locus (genetics); Gene; Biology; Adrenergic receptor; Genotype; Receptor","score_opus":0.036320427550297144,"score_gpt":0.34181502745054465,"score_spread":0.3054945999002475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022108999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900697,0.005946776,0.001007337,0.0011482072,0.00044265174,0.00017483304,0.000011377369,0.000015050502,0.0011841034],"genre_scores_gemma":[0.9853596,0.0012657255,0.01109,0.0002003289,0.0009418852,0.00003524608,0.000075651784,0.00003796473,0.0009935823],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99849176,0.00009657726,0.0001726879,0.00046044064,0.00031348786,0.0004650657],"domain_scores_gemma":[0.9993091,0.000010221372,0.000029384648,0.00033712274,0.00012372062,0.0001904331],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068958895,0.00013349832,0.00011990009,0.000092068265,0.00023385051,0.000058539972,0.0002269474,0.00016653756,0.00021015941],"category_scores_gemma":[0.000051994528,0.00012294904,0.00006348431,0.00018154821,0.00010514046,0.000004438166,0.00015461091,0.0002208626,0.00006354015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000087668726,0.00007414,0.0040211314,0.000019734724,0.000036566587,0.0000017705188,0.00003144648,0.000052575902,0.988804,0.0029081712,0.0023850054,0.0015777814],"study_design_scores_gemma":[0.0018765436,0.0012498038,0.002681524,0.00006413513,0.000012807849,0.000051977004,0.00036097583,0.000022265694,0.9491955,0.01079947,0.033231717,0.00045329015],"about_ca_topic_score_codex":0.000116377225,"about_ca_topic_score_gemma":0.00007910583,"teacher_disagreement_score":0.03960852,"about_ca_system_score_codex":0.000018364504,"about_ca_system_score_gemma":0.00019966821,"threshold_uncertainty_score":0.5013717},"labels":[],"label_agreement":null},{"id":"W2022116685","doi":"10.1021/jm100679e","title":"Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators","year":2010,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Eli Lilly and Company","keywords":"Chemistry; Allosteric regulation; AMPA receptor; Ion channel; Ligand efficiency; Drug discovery; Small molecule; Allosteric modulator; Ligand (biochemistry); Lead compound; Tolerability; Combinatorial chemistry; Stereochemistry; Computational biology; Biophysics; Receptor; Biochemistry; Pharmacology; Glutamate receptor","score_opus":0.007205475420284099,"score_gpt":0.22822599176542957,"score_spread":0.22102051634514547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022116685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83849347,0.0002181019,0.1608807,0.00006077586,0.00015598451,0.00011361762,0.000026062842,0.0000011793943,0.000050096143],"genre_scores_gemma":[0.98377216,0.00008624453,0.015552108,0.000017689352,0.00038960832,0.000002613246,0.00008642261,0.000018463517,0.00007466745],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887425,0.000018923642,0.000543641,0.00014738276,0.00029399016,0.000121795456],"domain_scores_gemma":[0.9982602,0.000024986746,0.000992708,0.00013476177,0.0005100799,0.00007725134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003106927,0.00014978541,0.000358604,0.00006739086,0.000022901982,0.000008278198,0.00015679083,0.00018941985,0.000028295291],"category_scores_gemma":[0.00012087052,0.00011207791,0.00019249151,0.00011845361,0.0001160965,0.00002302387,0.000018595132,0.00017069686,1.5681689e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014615526,0.00009584501,0.00007057691,0.0001881735,0.00015258347,8.638769e-7,0.00020763816,0.0022683984,0.99525046,0.000009167287,0.00008523763,0.00020949317],"study_design_scores_gemma":[0.0012723494,0.001282152,0.000041064926,0.00032093612,0.000094338044,0.000047412326,0.00065048155,0.0008449779,0.9952268,0.000057995978,0.000057507474,0.000104009545],"about_ca_topic_score_codex":0.000012957861,"about_ca_topic_score_gemma":0.0000029251337,"teacher_disagreement_score":0.14532858,"about_ca_system_score_codex":0.000011806636,"about_ca_system_score_gemma":0.00020990877,"threshold_uncertainty_score":0.45704046},"labels":[],"label_agreement":null},{"id":"W2022224915","doi":"10.1177/108705710000500504","title":"Impact of a Red-Shifted Dye Label for High Throughput Fluorescence Polarization Assays of G Protein–Coupled Receptors","year":2000,"lang":"en","type":"article","venue":"SLAS DISCOVERY","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BioPhage Pharma (Canada)","funders":"","keywords":"Fluorescein; Tartrazine; Fluorescence anisotropy; Fluorescence; BODIPY; G protein-coupled receptor; Chemistry; High-throughput screening; Receptor; Biophysics; Chromatography; Biochemistry; Membrane; Biology; Optics","score_opus":0.00952652462042239,"score_gpt":0.25691187755015593,"score_spread":0.24738535292973354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022224915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98768026,0.00018316586,0.011245035,0.000020206948,0.00009692906,0.0005154646,0.00012886297,0.000008947292,0.00012111836],"genre_scores_gemma":[0.9938323,0.00007940812,0.00449873,0.000011388565,0.000109258894,0.000036860827,0.0003831634,0.000030266183,0.0010186336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989397,0.000047145164,0.0003292767,0.00030017865,0.00015961661,0.00022408957],"domain_scores_gemma":[0.99934965,0.000013454344,0.00018384779,0.00029152833,0.00011835766,0.00004315441],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001762656,0.000167944,0.00024336897,0.00003870308,0.000052150313,0.000021168915,0.00016908147,0.00017781761,0.00025465392],"category_scores_gemma":[0.00008908535,0.00014291138,0.00017947235,0.00014181719,0.000061605766,0.000023635823,0.000032830496,0.0000570681,0.0000016707294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004537909,0.00013980156,0.0010601272,0.000045103327,0.000104427854,2.289055e-7,0.000036057292,0.0001337078,0.9950283,0.0008657377,0.0001335408,0.0019991894],"study_design_scores_gemma":[0.001048337,0.0013073925,0.0016781868,0.00007912769,0.000031810527,0.0000010645791,0.000022718754,0.0006051407,0.993511,0.0013747384,0.00014225501,0.00019821823],"about_ca_topic_score_codex":0.00021651993,"about_ca_topic_score_gemma":0.000009181303,"teacher_disagreement_score":0.006746305,"about_ca_system_score_codex":0.000022492555,"about_ca_system_score_gemma":0.00013965149,"threshold_uncertainty_score":0.58277565},"labels":[],"label_agreement":null},{"id":"W2022232781","doi":"10.1016/j.bpj.2012.11.181","title":"Functional Comparison of Monomers and Tetramers of the M2 Muscarinic Receptor","year":2013,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Monomer; Phospholipid; Agonist; Muscarinic acetylcholine receptor; IC50; Vesicle; Stereochemistry; Binding site; Oxotremorine; Allosteric regulation; Membrane; Biophysics; Receptor; Biochemistry; In vitro; Biology; Organic chemistry","score_opus":0.013829165027613447,"score_gpt":0.23790473437873555,"score_spread":0.2240755693511221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022232781","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99867845,0.00009382064,0.00070217723,0.00011385017,0.00024629617,0.000059438906,0.0000034428222,0.0000010991741,0.00010143278],"genre_scores_gemma":[0.999185,0.00003758289,0.0004591491,0.00003220071,0.00020035813,0.0000019971305,0.0000029202731,0.0000065752515,0.00007417879],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99942464,0.000038109007,0.00020893056,0.0000976711,0.0001306721,0.000099974175],"domain_scores_gemma":[0.9995864,0.000012076717,0.00016178633,0.000097171906,0.00008104815,0.00006152621],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000064178625,0.00007185661,0.00013319646,0.0000170021,0.000056302528,0.000012798045,0.00010523565,0.00005973193,0.00017540948],"category_scores_gemma":[0.000021728256,0.00004710824,0.00012280479,0.000049868937,0.00011200957,0.0000044160565,0.000052292824,0.00011465172,0.0000034983764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018980669,0.00005316512,0.002089326,0.000005641015,0.000041231953,2.6404367e-8,0.000031324373,0.00004076614,0.99231285,0.00009792016,0.0010804511,0.004228294],"study_design_scores_gemma":[0.00024678546,0.00024223857,0.013823703,0.000014067261,0.000014640713,0.0000049167584,0.00026697174,0.00018943202,0.9841558,0.000089438625,0.00088399963,0.000068039866],"about_ca_topic_score_codex":0.000011969751,"about_ca_topic_score_gemma":3.8277398e-7,"teacher_disagreement_score":0.011734377,"about_ca_system_score_codex":0.0000050193357,"about_ca_system_score_gemma":0.00002888326,"threshold_uncertainty_score":0.19210182},"labels":[],"label_agreement":null},{"id":"W2022367181","doi":"10.1021/ja0753703","title":"Understanding cAMP-Dependent Allostery by NMR Spectroscopy:  Comparative Analysis of the EPAC1 cAMP-Binding Domain in Its Apo and cAMP-Bound States","year":2007,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Serbian Academy of Sciences and Arts; Heart and Stroke Foundation of Canada","keywords":"Chemistry; Allosteric regulation; Nuclear magnetic resonance spectroscopy; Biophysics; Biochemistry; Stereochemistry; Enzyme","score_opus":0.022260395889622593,"score_gpt":0.28190213340777065,"score_spread":0.25964173751814806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022367181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99452245,0.00042068993,0.0045778416,0.0002522884,0.0000636282,0.00009066051,0.000027173419,0.0000014255697,0.000043852397],"genre_scores_gemma":[0.99841255,0.0002623126,0.0009835514,0.00022682917,0.00006842226,8.032225e-7,0.0000068265035,0.0000100926745,0.000028600994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986454,0.00009550633,0.00045813023,0.00019145249,0.00033037935,0.0002791135],"domain_scores_gemma":[0.9988175,0.000096476964,0.0007703899,0.0001645113,0.00006413185,0.00008699008],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00075215515,0.0001600038,0.00045402985,0.000036653837,0.00010359584,0.000032092,0.00030808692,0.00007839323,0.000017129649],"category_scores_gemma":[0.00003491401,0.00009860902,0.00044730378,0.00046281167,0.00030223496,0.000008957244,0.00015816302,0.0003094712,1.4552919e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088966015,0.000045876302,0.00707757,0.0000065268623,0.0006487478,8.686851e-7,0.0013355108,0.00019191999,0.9900136,0.000015552212,0.00056063454,0.000014250685],"study_design_scores_gemma":[0.0003808599,0.00010189393,0.00069214724,0.00003309018,0.00019184561,0.00001255196,0.01021015,0.00017753213,0.987739,0.00019577921,0.00013673959,0.00012836988],"about_ca_topic_score_codex":0.00004217208,"about_ca_topic_score_gemma":0.00003983226,"teacher_disagreement_score":0.00887464,"about_ca_system_score_codex":0.00024081195,"about_ca_system_score_gemma":0.000057510624,"threshold_uncertainty_score":0.4021159},"labels":[],"label_agreement":null},{"id":"W2022549388","doi":"10.1016/j.cellsig.2009.11.004","title":"Serotonin 4 receptor (5-HT4R) internalization is isoform-specific: Effects of 5-HT and RS67333 on isoforms A and B","year":2009,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Internalization; Gene isoform; Cell biology; Biology; Receptor; HEK 293 cells; Serotonin; G protein-coupled receptor; Endocytic cycle; Endocytosis; Signal transduction; Biochemistry","score_opus":0.005230271928080682,"score_gpt":0.2026126590388084,"score_spread":0.19738238711072773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022549388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9121033,0.0031264117,0.08409273,0.00005442082,0.00012055104,0.0002768965,0.0000056887156,0.000012739878,0.00020726644],"genre_scores_gemma":[0.99582475,0.0015352706,0.0018712953,0.00028182237,0.0001589023,0.0000069477387,0.00005498948,0.000022924802,0.00024309156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998912,0.000036932455,0.00029473015,0.0003877174,0.00015108002,0.00021757046],"domain_scores_gemma":[0.9994982,0.00002263706,0.00014805261,0.00017602372,0.000060887545,0.00009420469],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021635738,0.00020018737,0.00021314395,0.00006899108,0.00008613044,0.00004294209,0.00010729659,0.00016983713,0.000041231306],"category_scores_gemma":[0.000027517046,0.00017681217,0.000072277595,0.000072450624,0.000040599305,0.000009724576,0.00004229747,0.000100061225,0.0000041984927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013738363,0.00004276194,0.000077089295,0.00005731188,0.000027043241,0.000002534828,0.00028424172,0.00004926197,0.9896829,0.0005679031,0.00015509655,0.008916488],"study_design_scores_gemma":[0.00070491567,0.0011071297,0.000057327645,0.00017803526,0.000014286335,0.0000038399053,0.00005668511,0.0006879496,0.9911092,0.0004844695,0.005390273,0.00020589825],"about_ca_topic_score_codex":0.00000387839,"about_ca_topic_score_gemma":3.5545153e-7,"teacher_disagreement_score":0.08372146,"about_ca_system_score_codex":0.000010239738,"about_ca_system_score_gemma":0.000013075796,"threshold_uncertainty_score":0.72101915},"labels":[],"label_agreement":null},{"id":"W2022946791","doi":"10.1074/jbc.m114.618819","title":"Development and Characterization of Pepducins as Gs-biased Allosteric Agonists*","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; National Heart, Lung, and Blood Institute; National Institute of Environmental Health Sciences; Canadian Institutes of Health Research","keywords":"Allosteric regulation; Characterization (materials science); Chemistry; Economics; Nanotechnology; Biochemistry; Receptor; Materials science","score_opus":0.01564643145743214,"score_gpt":0.2321576558510961,"score_spread":0.21651122439366396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022946791","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978236,0.00010388732,0.0017051336,0.00003734806,0.000055063298,0.00002823755,0.0000023686441,0.0000022700146,0.00024211433],"genre_scores_gemma":[0.99719304,0.00014245324,0.002204939,0.0000971258,0.00020659168,0.000001121116,0.000041498573,0.000006104479,0.00010709985],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927574,0.000028220496,0.00035349774,0.0001357063,0.00009750558,0.00010930746],"domain_scores_gemma":[0.9993885,0.000011255876,0.00032822284,0.00008542113,0.00010099103,0.000085613516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028302922,0.00010307778,0.00019909209,0.000012564559,0.000034166394,0.000012471423,0.00011483498,0.00016400199,0.00008805899],"category_scores_gemma":[0.000113533,0.00007456206,0.00006759718,0.000031768155,0.000045956633,0.0000031373472,0.000054087417,0.00008047754,9.3039057e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008090705,0.00004128155,0.0005961318,0.000025217187,0.000025972506,0.000001862999,0.000024754048,0.0000012068232,0.9955172,0.000011283175,0.000006216617,0.0036679902],"study_design_scores_gemma":[0.00029943863,0.00025900404,0.0019387295,0.000027711776,0.000007443089,0.00007860739,0.000032377982,0.00000754251,0.98123944,0.00003044024,0.015985714,0.000093564995],"about_ca_topic_score_codex":3.527791e-7,"about_ca_topic_score_gemma":6.458323e-8,"teacher_disagreement_score":0.015979499,"about_ca_system_score_codex":0.000008018677,"about_ca_system_score_gemma":0.00004526693,"threshold_uncertainty_score":0.3040552},"labels":[],"label_agreement":null},{"id":"W2023105352","doi":"10.1097/01.hjh.0000379699.52889.7c","title":"BLOCKADE OF TACHYKININ NK-3 RECEPTOR REVERSES HYPERTENSION THROUGH A DOPAMINERGIC MECHANISM IN THE VENTRAL TEGMENTAL AREA OF SPONTANEOUSLY HYPERTENSIVE RATS: PP.29.161","year":2010,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Ventral tegmental area; Internal medicine; Endocrinology; Medicine; Raclopride; Agonist; Dopamine; Dopaminergic; Mean arterial pressure; Receptor; Heart rate; Blood pressure","score_opus":0.018767632168355235,"score_gpt":0.22370258065564244,"score_spread":0.20493494848728722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023105352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968197,0.0013477632,0.00012960883,0.0004049796,0.0009850181,0.00023176511,0.00001730922,0.0000038894377,0.00005999611],"genre_scores_gemma":[0.99312866,0.0012601162,0.0045601553,0.0005748787,0.00037305502,0.0000031792033,0.000027532633,0.000034524215,0.00003791577],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977536,0.0001766813,0.0009182624,0.0002940958,0.0005404551,0.00031691004],"domain_scores_gemma":[0.998089,0.00009255853,0.00076261465,0.00039265628,0.0005607626,0.000102370206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006787566,0.00028501096,0.0006815104,0.00011115567,0.000080994476,0.000016962189,0.00042037456,0.00030330513,0.00009970952],"category_scores_gemma":[0.0004073031,0.00018510969,0.00036632144,0.00018966779,0.00011217516,0.000027344495,0.00009394651,0.00049204094,0.0000022310705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006218858,0.00034119675,0.00007052003,0.000026789907,0.000075683616,0.00043190652,0.00026458208,0.000060370985,0.9955778,0.00011714134,0.0019838316,0.00042828763],"study_design_scores_gemma":[0.0016244332,0.0017446445,0.00014025661,0.00023262555,0.00013019686,0.0069000633,0.00234787,0.00018732916,0.9830191,0.00030353505,0.0031397394,0.00023017438],"about_ca_topic_score_codex":0.00008363352,"about_ca_topic_score_gemma":0.000033087803,"teacher_disagreement_score":0.012558672,"about_ca_system_score_codex":0.00001890314,"about_ca_system_score_gemma":0.00014781985,"threshold_uncertainty_score":0.7548554},"labels":[],"label_agreement":null},{"id":"W2023243427","doi":"10.1074/jbc.m202723200","title":"Threonine 308 within a Putative Casein Kinase 2 Site of the Cytoplasmic Tail of Leukotriene B4 Receptor (BLT1) Is Crucial for Ligand-induced, G-protein-coupled Receptor-specific Kinase 6-mediated Desensitization","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Desensitization (medicine); Receptor; Casein kinase 2; Homologous desensitization; Chemistry; Threonine; Ligand (biochemistry); Protein kinase A; G protein-coupled receptor kinase; Leukotriene receptor; Protein kinase C; Kinase; Biochemistry; G protein-coupled receptor; Cell biology; Biology; Mitogen-activated protein kinase kinase; Phosphorylation; Antagonist; Serine","score_opus":0.027746886873746553,"score_gpt":0.23537148604567154,"score_spread":0.207624599171925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023243427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99646467,0.0011483941,0.0013554764,0.000249871,0.00025073122,0.0003113021,0.00018495036,0.000006541542,0.000028073846],"genre_scores_gemma":[0.9962049,0.00046424178,0.0023339598,0.000081764796,0.0006612814,0.0000129057125,0.00010003752,0.000025304495,0.000115567454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99802005,0.000096592856,0.0009632635,0.00034509503,0.00029253372,0.00028247506],"domain_scores_gemma":[0.9975342,0.0000771837,0.0012860094,0.00026308882,0.0006960081,0.00014347266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005275764,0.00028431133,0.00053737964,0.00004030248,0.00011307394,0.000019956082,0.00029898592,0.00049763476,0.0003129959],"category_scores_gemma":[0.00062770874,0.00018974554,0.00041401395,0.00025184045,0.00017593749,0.0000126751265,0.00009268189,0.00029331754,0.0000028282896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00075820717,0.00017991992,0.0001733545,0.000056798635,0.00009018397,0.000006077223,0.00018553942,0.00009241118,0.9974665,0.000010985221,0.0004979451,0.00048210096],"study_design_scores_gemma":[0.001585698,0.00091890444,0.000041047377,0.00010492406,0.00003040443,0.0000424453,0.0003639776,0.00041006878,0.9950972,0.0000834679,0.0010996651,0.00022217397],"about_ca_topic_score_codex":0.000005078371,"about_ca_topic_score_gemma":7.8892634e-7,"teacher_disagreement_score":0.0023692537,"about_ca_system_score_codex":0.000056999488,"about_ca_system_score_gemma":0.00009983462,"threshold_uncertainty_score":0.77375984},"labels":[],"label_agreement":null},{"id":"W2023407489","doi":"10.1074/jbc.m114.568816","title":"Concomitant Action of Structural Elements and Receptor Phosphorylation Determines Arrestin-3 Interaction with the Free Fatty Acid Receptor FFA4","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Canadian Institutes of Health Research; Strategiske Forskningsråd","keywords":"Arrestin; GPR120; Phosphorylation; Receptor; Biochemistry; Free fatty acid receptor 1; G protein-coupled receptor; Mutagenesis; Free fatty acid receptor; Fatty acid; Chemistry; Biology; Agonist; Cell biology; Mutant; Gene; Polyunsaturated fatty acid","score_opus":0.01793904630163027,"score_gpt":0.2555902149515173,"score_spread":0.23765116864988703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023407489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99720716,0.00025584907,0.0021108624,0.00013034233,0.00016693425,0.000060449795,0.000008471082,0.000003274627,0.00005665927],"genre_scores_gemma":[0.99638045,0.00012700677,0.002958672,0.000040979652,0.0004366902,0.000002583302,0.000024400693,0.000007393917,0.000021838574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991823,0.00006458186,0.00034600074,0.0001546906,0.00013394622,0.00011850829],"domain_scores_gemma":[0.99899244,0.00004469025,0.0005906151,0.0001416633,0.00016835162,0.000062218984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031998838,0.00013310862,0.00019221572,0.000011304448,0.00006755529,0.000020754436,0.00017396774,0.00015196252,0.000118471726],"category_scores_gemma":[0.00025616458,0.000071831295,0.00007627233,0.000039736682,0.00009732764,0.000010699285,0.00005543805,0.0001693305,3.6920525e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048685854,0.000014122894,0.004074142,0.000017766262,0.000043301185,3.275356e-7,0.00001989132,0.000014379269,0.9898459,0.0000036203007,0.0002011061,0.0052786027],"study_design_scores_gemma":[0.000583023,0.0006346143,0.001527571,0.000038945673,0.0000188728,0.000050831673,0.00023396476,0.000081961014,0.9942716,0.00006571908,0.0023932129,0.00009972133],"about_ca_topic_score_codex":0.0000019945503,"about_ca_topic_score_gemma":0.0000014047811,"teacher_disagreement_score":0.0051788813,"about_ca_system_score_codex":0.000017301121,"about_ca_system_score_gemma":0.000020384712,"threshold_uncertainty_score":0.29291952},"labels":[],"label_agreement":null},{"id":"W2023437958","doi":"10.1046/j.0953-816x.2001.01583.x","title":"Effect of the selective noradrenergic reuptake inhibitor reboxetine on the firing activity of noradrenaline and serotonin neurons","year":2001,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Reboxetine; Chemistry; Agonist; Locus coeruleus; Reuptake; Reuptake inhibitor; Dorsal raphe nucleus; Serotonin; Pharmacology; Endocrinology; Internal medicine; Medicine; Serotonergic; Receptor; Central nervous system","score_opus":0.012238922395825991,"score_gpt":0.23471881715660162,"score_spread":0.22247989476077562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023437958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987648,0.00008108611,0.00029626067,0.00027674038,0.0002511434,0.00011342111,0.0000030486242,0.0000016841269,0.00021178849],"genre_scores_gemma":[0.99952114,0.000099251156,0.000037125526,0.00013277058,0.00012311905,5.4286454e-7,1.3228343e-7,0.000013846893,0.000072077564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829394,0.0008690094,0.00026330343,0.00018377221,0.0002510372,0.00013894367],"domain_scores_gemma":[0.9990601,0.00008337734,0.00045694687,0.00023180319,0.00011205571,0.000055748405],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001277943,0.000121399375,0.00016012005,0.000038519014,0.00012268224,0.000018934368,0.00039282942,0.000017915605,0.0000031873697],"category_scores_gemma":[0.00070439465,0.00006434411,0.000099043835,0.00026597234,0.00018402548,0.0000088898905,0.00014125406,0.0002117002,2.2904702e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022709131,0.000030240035,0.0005639178,0.000007476135,0.000003909059,0.000013457574,0.000031478616,0.0006399249,0.9963217,0.0000096507865,0.00004879244,0.0021023632],"study_design_scores_gemma":[0.00033993827,0.002823715,0.015000496,0.00006293547,0.0000140968305,0.0001542328,0.000005399972,0.00017172228,0.98056376,0.000003561641,0.00080202223,0.000058095815],"about_ca_topic_score_codex":0.000001343032,"about_ca_topic_score_gemma":8.139503e-7,"teacher_disagreement_score":0.015757915,"about_ca_system_score_codex":0.000004740124,"about_ca_system_score_gemma":0.00003585738,"threshold_uncertainty_score":0.26238766},"labels":[],"label_agreement":null},{"id":"W2023575959","doi":"10.1016/s0895-7061(01)01753-8","title":"ACE2 - a novel candidate gene for hypertension","year":2001,"lang":"en","type":"article","venue":"American Journal of Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Internal medicine; Endocrinology; Medicine; Blood pressure; Angiotensin-converting enzyme 2; Gene expression; Spontaneously hypertensive rat; Candidate gene; Blot; Gene; Angiotensin II; Biology; Genetics","score_opus":0.020739739965028495,"score_gpt":0.2386949797439695,"score_spread":0.217955239778941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023575959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9505351,0.0007494853,0.047812283,0.00044323583,0.0003328812,0.00009745652,0.0000052159567,0.0000045392962,0.000019796063],"genre_scores_gemma":[0.9791725,0.0009904914,0.017989086,0.0011894215,0.0005200935,0.0000028566308,0.00001827737,0.000031719246,0.00008551353],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990281,0.000030186764,0.0003264918,0.00019885077,0.00017464947,0.00024171673],"domain_scores_gemma":[0.99892527,0.000023823935,0.00032963193,0.00017417826,0.00040791064,0.00013920739],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027787298,0.00014812178,0.00032568784,0.000077325545,0.00009532557,0.000017696286,0.00015646378,0.00006104231,0.00001574231],"category_scores_gemma":[0.00010681757,0.00011246758,0.00020321016,0.00010972277,0.000065080174,0.000009701259,0.000040579525,0.0000879432,0.000002132255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053288403,0.00007410856,0.00009037497,0.0000022617457,0.00005812916,0.000031283926,0.000015724132,0.00013091251,0.97849506,0.000010226644,0.0010265537,0.019532502],"study_design_scores_gemma":[0.0028368894,0.004882882,0.00049106573,0.00007331646,0.00013988459,0.005801979,0.00048422642,0.0008739703,0.9117235,0.00009815206,0.07220311,0.0003910199],"about_ca_topic_score_codex":0.00003388126,"about_ca_topic_score_gemma":0.0000040605787,"teacher_disagreement_score":0.07117656,"about_ca_system_score_codex":0.000013769165,"about_ca_system_score_gemma":0.00007499503,"threshold_uncertainty_score":0.45862946},"labels":[],"label_agreement":null},{"id":"W2023614504","doi":"10.1016/s0003-2697(03)00354-3","title":"A functional assay for G-protein-coupled receptors using stably transformed insect tissue culture cell lines","year":2003,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Killam Trusts; University of Toronto; University of Pennsylvania","keywords":"G protein-coupled receptor; Sf9; Receptor; Biology; Agonist; HEK 293 cells; Cell biology; Cell culture; Heterotrimeric G protein; Aequorin; G protein; Biochemistry; Spodoptera; Recombinant DNA; Intracellular; Gene","score_opus":0.02053506250318589,"score_gpt":0.25638882676306235,"score_spread":0.23585376425987647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023614504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8840332,0.00086838356,0.11302818,0.000060593586,0.00022808378,0.000377933,0.000053202933,0.000027105769,0.0013233364],"genre_scores_gemma":[0.9843929,0.000044596312,0.007928515,0.00014358095,0.0004894164,0.000045666693,0.00041277453,0.00004568282,0.006496884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983579,0.000042545398,0.00034486473,0.00058666954,0.00022536947,0.0004426702],"domain_scores_gemma":[0.9991843,0.000020142472,0.00009024113,0.00028050388,0.00021465433,0.00021015538],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003418867,0.0003044834,0.0002662496,0.000032440093,0.00017264562,0.000052135634,0.00015432721,0.00047543333,0.0005459325],"category_scores_gemma":[0.00028461165,0.0002743089,0.0002567931,0.00016320785,0.00007561723,0.0000068411136,0.000023720635,0.00016591308,0.000007947555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011048164,0.000092507275,0.000028205606,0.000087664695,0.00007199186,0.0000015855807,0.000013039932,0.00007095206,0.997504,0.00014352828,0.0016973974,0.00017866229],"study_design_scores_gemma":[0.000830368,0.00019775113,0.000001496649,0.000023294742,0.00006742798,0.000012213386,0.00012376724,0.0012259446,0.9752209,0.00018524984,0.02174009,0.0003714735],"about_ca_topic_score_codex":0.000008495756,"about_ca_topic_score_gemma":0.0000023965958,"teacher_disagreement_score":0.10509966,"about_ca_system_score_codex":0.000044018903,"about_ca_system_score_gemma":0.00022073611,"threshold_uncertainty_score":0.9999709},"labels":[],"label_agreement":null},{"id":"W2023649595","doi":"10.1038/nmeth743","title":"Real-time monitoring of receptor and G-protein interactions in living cells","year":2005,"lang":"en","type":"article","venue":"Nature Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":417,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; Université de Montréal","funders":"","keywords":"G protein-coupled receptor; Receptor; Förster resonance energy transfer; G protein; Agonist; Protein subunit; Signal transduction; Cell biology; HEK 293 cells; Chemistry; Biophysics; Bioluminescence; Biology; Biochemistry; Fluorescence; Gene","score_opus":0.011282536160841392,"score_gpt":0.3418913524541902,"score_spread":0.3306088162933488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023649595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99170285,0.0010408252,0.005997901,0.00004301359,0.0002580134,0.00010293389,0.0000031767363,0.000007854438,0.0008434302],"genre_scores_gemma":[0.53150916,0.00017528847,0.46714166,0.000010225177,0.0002830603,0.0000071818617,0.0000026413209,0.000012440547,0.00085833366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923176,0.00019238198,0.00017575973,0.00020810662,0.00006291757,0.00012907153],"domain_scores_gemma":[0.9996343,0.000063829895,0.000070597765,0.00014854316,0.000042551696,0.000040162606],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064444845,0.00009522504,0.00013932792,0.00006298691,0.000028139937,0.000010702228,0.000081479455,0.00019147394,0.000104556995],"category_scores_gemma":[0.00016959549,0.0000911713,0.00004583426,0.00008253651,0.000016769282,0.000005802232,0.000063620406,0.00024359665,0.0000019928975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014268228,0.000019590438,0.0002667676,0.0000105250565,0.000010659089,1.6437107e-7,0.000083903185,0.000027277358,0.9736034,0.000034743964,0.000057428577,0.025871228],"study_design_scores_gemma":[0.00009103753,0.00004131179,0.00036235695,0.000080317746,0.0000045636652,0.0000015387086,0.00006178212,0.000104079525,0.99022615,0.000040363444,0.008894934,0.000091557384],"about_ca_topic_score_codex":0.000017970156,"about_ca_topic_score_gemma":0.0000032691778,"teacher_disagreement_score":0.46114376,"about_ca_system_score_codex":0.000014930416,"about_ca_system_score_gemma":0.00001686956,"threshold_uncertainty_score":0.37178576},"labels":[],"label_agreement":null},{"id":"W2023845267","doi":"10.1038/npp.2013.148","title":"Heteromeric Dopamine Receptor Signaling Complexes: Emerging Neurobiology and Disease Relevance","year":2013,"lang":"en","type":"review","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":163,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"Homomeric; Neuroscience; Dopamine; Dopamine receptor; Receptor; Disease; Pharmacology; Biology; Medicine; Internal medicine","score_opus":0.027621760259142265,"score_gpt":0.32444596650607055,"score_spread":0.2968242062469283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2023845267","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010850917,0.9846424,0.00026128066,0.00008845834,0.002776731,0.0011536402,0.00009915818,0.000063499356,0.000063908745],"genre_scores_gemma":[0.00040418355,0.9950499,0.0005805755,0.001035353,0.001213699,0.00037838315,0.00046263397,0.00020472099,0.0006705464],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959621,0.0008078899,0.00085696543,0.0015009013,0.00014144868,0.00073073414],"domain_scores_gemma":[0.99811023,0.00015362092,0.0005468847,0.0005427397,0.00009479346,0.00055170996],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018955914,0.0008305824,0.0014016746,0.00021039495,0.00020277001,0.000058945225,0.0005618612,0.0004123653,0.0008817037],"category_scores_gemma":[0.00015495063,0.00074877765,0.00042320899,0.00024458993,0.00021978187,0.000009895718,0.0003546805,0.00061929825,0.0001708047],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010897558,0.000099741614,0.00000430372,0.0028247372,0.00023407742,0.00003907905,0.000009717947,0.000018066094,0.49760616,0.00002724517,0.008064449,0.49096346],"study_design_scores_gemma":[0.0005446841,0.0004160029,0.0000018614586,0.0004054966,0.00034783152,0.00008489294,0.000004445734,0.000017756971,0.00075482286,0.000021135722,0.9967375,0.0006635846],"about_ca_topic_score_codex":0.0000034969653,"about_ca_topic_score_gemma":3.607465e-7,"teacher_disagreement_score":0.98867303,"about_ca_system_score_codex":0.000022866618,"about_ca_system_score_gemma":0.00014387985,"threshold_uncertainty_score":0.99949634},"labels":[],"label_agreement":null},{"id":"W2024008511","doi":"10.1021/bi025533u","title":"Activation-Induced Subcellular Redistribution of Gα<sub>s</sub> Is Dependent upon Its Unique N-Terminus","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; Centre for Addiction and Mental Health","funders":"National Institute of General Medical Sciences","keywords":"Palmitoylation; Cytoplasm; Heterotrimeric G protein; Cell biology; N-terminus; Mutant; Subcellular localization; G alpha subunit; Cell fractionation; G protein; Membrane; Chemistry; C-terminus; Protein subunit; Biology; Biochemistry; Peptide sequence; Signal transduction; Cysteine; Amino acid","score_opus":0.015194253289550931,"score_gpt":0.21902181628771314,"score_spread":0.2038275629981622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024008511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965702,0.00046568373,0.001899644,0.000074364754,0.00011497843,0.00014642942,0.000068890644,0.000019694471,0.00064009725],"genre_scores_gemma":[0.99876165,0.00014554533,0.00009586942,0.0000676867,0.00026514172,0.000020024938,0.00032936092,0.000026974802,0.0002877196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99868953,0.000033354747,0.00032607093,0.0004427973,0.00023944747,0.00026876808],"domain_scores_gemma":[0.99907124,0.000009560075,0.00020782991,0.00041490322,0.00018344606,0.00011303051],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014943785,0.00022116149,0.00018514492,0.000029872577,0.00008015634,0.000020934653,0.00021706213,0.00041077114,0.00015836967],"category_scores_gemma":[0.000091682225,0.00023780864,0.00014038621,0.00010925949,0.000024855253,0.0000069028933,0.000083244544,0.00012971931,0.000014229961],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030450386,0.000086340944,0.000023055909,0.000062500025,0.000039404727,0.00000640547,0.000025990328,0.0000036570104,0.99723494,0.00002340439,0.0011201669,0.0013436645],"study_design_scores_gemma":[0.0003769244,0.00010850483,0.000012836878,0.000045952977,0.000017733548,0.000025800928,0.000040382554,0.00028302483,0.99836737,0.000030652496,0.00043756902,0.00025326948],"about_ca_topic_score_codex":0.0000048073043,"about_ca_topic_score_gemma":4.9265356e-7,"teacher_disagreement_score":0.0021914593,"about_ca_system_score_codex":0.000046613994,"about_ca_system_score_gemma":0.000053021056,"threshold_uncertainty_score":0.9697555},"labels":[],"label_agreement":null},{"id":"W2024017898","doi":"10.1016/j.neuropharm.2005.10.004","title":"ERβ mediates the estradiol increase of D2 receptors in rat striatum and nucleus accumbens","year":2005,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; Université Laval","keywords":"Quinpirole; Internal medicine; Endocrinology; Agonist; Nucleus accumbens; Chemistry; Spiperone; Receptor; Estrogen receptor; Striatum; Ovariectomized rat; Estrogen; Biology; Dopamine; Medicine","score_opus":0.009953349514449332,"score_gpt":0.25766748984363796,"score_spread":0.24771414032918862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024017898","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980961,0.00065997796,0.000017660634,0.0004061614,0.00043825817,0.00019099728,0.000008761275,0.000007542716,0.00017452994],"genre_scores_gemma":[0.9972482,0.001293385,0.0002011149,0.0007492689,0.0003596322,0.00001568782,0.000011798859,0.00001965545,0.00010129512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896663,0.00021443605,0.00024880888,0.00026605657,0.00007700781,0.0002270453],"domain_scores_gemma":[0.9995667,0.00008375084,0.00009430795,0.00014582198,0.0000322894,0.00007714882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021600632,0.00013355394,0.00017141177,0.00004720775,0.000047557205,0.000009386328,0.00019121295,0.00011574243,0.00023611476],"category_scores_gemma":[0.000107224754,0.000104272134,0.00004863335,0.000086577915,0.000108268134,0.000004954923,0.00010314828,0.00016986988,0.0000048783477],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001391762,0.000051912808,0.0015656061,0.00000723894,0.000017919474,0.000007108992,0.00005839614,0.00016848561,0.99079883,0.00006290622,0.0016472293,0.005475194],"study_design_scores_gemma":[0.0012459678,0.00032750418,0.0011082423,0.0000043832024,0.000029038962,0.000025702686,0.00005961544,0.00045140725,0.93978125,0.000031871557,0.056799363,0.00013567382],"about_ca_topic_score_codex":0.000028247461,"about_ca_topic_score_gemma":0.000021670285,"teacher_disagreement_score":0.055152133,"about_ca_system_score_codex":0.000008218805,"about_ca_system_score_gemma":0.00004860895,"threshold_uncertainty_score":0.42520943},"labels":[],"label_agreement":null},{"id":"W2024483556","doi":"10.1007/s00210-006-0060-7","title":"β-Adrenoceptor mediated responses in rat pulmonary artery: putative role of TASK-1 related K channels","year":2006,"lang":"en","type":"article","venue":"Naunyn-Schmiedeberg s Archives of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Pulmonary artery; Task (project management); Internal medicine; Cardiology; Medicine; Biology; Economics","score_opus":0.005289926324118036,"score_gpt":0.24537570757845648,"score_spread":0.24008578125433844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024483556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99343455,0.0025521659,0.0002905868,0.00019610226,0.00043279317,0.00040646672,0.00008772981,0.000019382813,0.0025802457],"genre_scores_gemma":[0.9973124,0.00032165067,0.0008481132,0.00010007407,0.00018515758,0.000058408208,0.00036576326,0.000041855434,0.00076656486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976316,0.0004978323,0.00075061654,0.00049951766,0.00017071856,0.00044971812],"domain_scores_gemma":[0.99900806,0.00027508143,0.00037461633,0.0001845241,0.00007698815,0.00008070472],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029978412,0.0002851449,0.0004916875,0.00034452253,0.000056583576,0.000006470091,0.00033472216,0.00024116911,0.0004529517],"category_scores_gemma":[0.000072907365,0.0002828076,0.00018701733,0.0002504299,0.0002963906,0.000011206167,0.00015650682,0.00023658734,0.000006781288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001667776,0.00034796484,0.00072961824,0.000034795823,0.00012236944,0.000025092917,0.00034840853,0.001199883,0.99321556,0.00026235692,0.0004845046,0.0015616396],"study_design_scores_gemma":[0.00155852,0.00056016387,0.0006889227,0.000029443476,0.00004077706,0.000019543513,0.00017784256,0.0017872845,0.9880532,0.0023421026,0.004484258,0.0002579256],"about_ca_topic_score_codex":0.00010332844,"about_ca_topic_score_gemma":0.000020838577,"teacher_disagreement_score":0.005162374,"about_ca_system_score_codex":0.000015672491,"about_ca_system_score_gemma":0.00017082997,"threshold_uncertainty_score":0.9999624},"labels":[],"label_agreement":null},{"id":"W2024489182","doi":"10.1016/j.devbrainres.2005.03.002","title":"Ontogeny of respiratory sensitivity and tolerance to the mu-opioid agonist fentanyl in rat","year":2005,"lang":"en","type":"article","venue":"Developmental Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Children's Hospital; McGill University Health Centre","funders":"","keywords":"Fentanyl; Respiratory system; ED50; Respiratory minute volume; Ventilation (architecture); Biology; Anesthesia; Plethysmograph; Tidal volume; Opioid; Drug tolerance; Ontogeny; Agonist; Respiration; Internal medicine; Endocrinology; Medicine; Pharmacology; Receptor; Anatomy","score_opus":0.03608323446448391,"score_gpt":0.3222618969924099,"score_spread":0.286178662527926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024489182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974153,0.00044889204,0.00015962623,0.0009437175,0.000061532905,0.00030502022,0.0000088097995,0.0000029734274,0.0006541353],"genre_scores_gemma":[0.9962204,0.00004127756,0.0020893558,0.0009671911,0.00013022403,0.000029869114,0.000011299874,0.000012327293,0.0004980671],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863595,0.00025478838,0.00020193945,0.00030332897,0.0002932394,0.0003107395],"domain_scores_gemma":[0.99955314,0.00007210317,0.000024463103,0.00016196375,0.00010315474,0.00008519022],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021251386,0.00009642675,0.00011401619,0.00007826946,0.00014659089,0.000030231959,0.00014625964,0.000076378004,0.000038620467],"category_scores_gemma":[0.00025062164,0.000079128935,0.000025991612,0.00019541648,0.000102517355,0.000005151254,0.00026271338,0.0001567976,0.000015260177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008019864,0.000030418123,0.003394468,0.000010754585,0.0000074290037,0.000005576833,0.00048668092,0.000029478726,0.97495663,0.000065747074,0.003848997,0.01708364],"study_design_scores_gemma":[0.00027856426,0.00009330831,0.00796643,0.000024468214,5.015072e-7,0.0000066513817,0.00059191557,0.00004139128,0.8778662,0.000012492025,0.11301642,0.00010166781],"about_ca_topic_score_codex":0.000063410196,"about_ca_topic_score_gemma":0.0016682902,"teacher_disagreement_score":0.10916743,"about_ca_system_score_codex":0.000058993406,"about_ca_system_score_gemma":0.00016835023,"threshold_uncertainty_score":0.32267845},"labels":[],"label_agreement":null},{"id":"W2024635398","doi":"10.1016/s0165-5728(02)00259-x","title":"Murine tumor necrosis factor-α sensitizes plasma corticosterone activity and the manifestation of shock: modulation by histamine","year":2002,"lang":"en","type":"article","venue":"Journal of Neuroimmunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Cimetidine; Histamine; Diphenhydramine; Sensitization; Endocrinology; Internal medicine; Corticosterone; Medicine; Tumor necrosis factor alpha; Dexamethasone; Mepyramine; Immunology; Antagonist; Receptor; Hormone","score_opus":0.011187285524808459,"score_gpt":0.20816387782221962,"score_spread":0.19697659229741116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024635398","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978261,0.0005935149,0.00094955997,0.00033594703,0.00018421955,0.00007804495,0.000008646126,0.0000021303388,0.000021848446],"genre_scores_gemma":[0.9989086,0.0006991775,0.00013028587,0.00006247392,0.00004602416,9.752388e-7,0.000003930559,0.000011024287,0.00013751481],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992267,0.00014583989,0.00030655062,0.00011222408,0.00009992939,0.00010876746],"domain_scores_gemma":[0.99922156,0.00005674738,0.00046217346,0.00012222887,0.0001124377,0.000024872192],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000115715215,0.00009835145,0.00021924858,0.000043029257,0.000050743558,0.000013013061,0.000081293714,0.00006208965,0.00004152318],"category_scores_gemma":[0.000099488665,0.000071246155,0.000067263885,0.0000374987,0.00011423239,0.00001089562,0.000043460816,0.00012621035,5.692017e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043908635,0.00005199011,0.00014677469,0.000007800121,0.000050300616,0.000006495498,0.00007669853,0.000051087995,0.99309283,0.000019572652,0.00010541228,0.0059519345],"study_design_scores_gemma":[0.0037788628,0.0017136947,0.04660977,0.000020398955,0.00005916651,0.0008897468,0.00007448201,0.0052843303,0.9404314,0.00008121755,0.00091062795,0.0001462794],"about_ca_topic_score_codex":0.000013038954,"about_ca_topic_score_gemma":0.00000262723,"teacher_disagreement_score":0.052661423,"about_ca_system_score_codex":0.00000965306,"about_ca_system_score_gemma":0.000008359947,"threshold_uncertainty_score":0.2905334},"labels":[],"label_agreement":null},{"id":"W2024744248","doi":"10.1016/j.jveb.2009.10.024","title":"Validation of a cognitive test battery for cats","year":2010,"lang":"en","type":"article","venue":"Journal of Veterinary Behavior","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Thornhill Medical (Canada)","funders":"","keywords":"Fructosamine; Medicine; Diabetes mellitus; Internal medicine; Gastroenterology; Glycation; Reference range; Endocrinology","score_opus":0.028011991471347825,"score_gpt":0.3169591032134605,"score_spread":0.2889471117421127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024744248","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963135,0.000040475818,0.0030261034,0.000015381658,0.0004287217,0.000121785626,0.00003629614,0.0000011547112,0.000016587803],"genre_scores_gemma":[0.9966191,0.000012621067,0.0029638915,0.000021686637,0.00028370172,0.000012418282,0.000022998158,0.000012481911,0.000051092287],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994708,0.000015236825,0.00025927785,0.000081889666,0.000086495544,0.000086352],"domain_scores_gemma":[0.9993092,0.00003860267,0.00026675456,0.00007481531,0.0002640455,0.000046627083],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020957296,0.00007155375,0.00012346008,0.000043853543,0.000028205544,0.000009803061,0.00009216308,0.00008618406,0.00006825236],"category_scores_gemma":[0.00013393094,0.00006302531,0.00012539946,0.000023106764,0.000025548794,0.0000069435773,0.000023872752,0.00008618446,6.048089e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001506167,0.00017288068,0.0022738199,0.000011108971,0.000013493067,0.00000992455,0.000037192767,0.0000010995615,0.99424917,0.0000017844467,0.00007470812,0.0030042185],"study_design_scores_gemma":[0.00057883095,0.003948235,0.0035827667,0.000036356974,0.00007126282,0.00037590353,0.00007086652,0.0000024319809,0.9906405,0.000011734537,0.0006068898,0.000074221636],"about_ca_topic_score_codex":0.0000011640927,"about_ca_topic_score_gemma":3.543928e-7,"teacher_disagreement_score":0.0037753545,"about_ca_system_score_codex":0.0000032598314,"about_ca_system_score_gemma":0.000044644756,"threshold_uncertainty_score":0.25700974},"labels":[],"label_agreement":null},{"id":"W2024925929","doi":"10.1111/j.1600-0854.2007.00692.x","title":"RACK1 Regulates the Cell Surface Expression of the G Protein‐Coupled Receptor for Thromboxane A<sub>2</sub>","year":2007,"lang":"en","type":"article","venue":"Traffic","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Hôpital Fleurimont; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cell biology; G protein-coupled receptor; Receptor; Biology; HEK 293 cells; Protease-activated receptor 2; 5-HT5A receptor; Protease-activated receptor; Cell surface receptor; Thromboxane receptor; Endoplasmic reticulum; Prostaglandin E2 receptor; Signal transduction; Biochemistry; Thromboxane A2; Thrombin; Agonist; Platelet","score_opus":0.007645962068838153,"score_gpt":0.21635333241376162,"score_spread":0.20870737034492345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024925929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99537426,0.0005837027,0.0028476366,0.00010670702,0.00022069942,0.0007992714,0.000009754627,0.000014408988,0.00004357535],"genre_scores_gemma":[0.99764144,0.00004028742,0.0017344014,0.000042640208,0.00016631774,0.000019287918,0.00002662072,0.000029491262,0.00029951535],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902385,0.000052031384,0.00025045642,0.00025217593,0.0001583921,0.000263088],"domain_scores_gemma":[0.99926347,0.00004160829,0.00016370729,0.00039797663,0.000090682894,0.000042585212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059302984,0.00014859332,0.00014647479,0.000011294343,0.000166312,0.000014948946,0.00030065823,0.00015997622,0.00002787148],"category_scores_gemma":[0.00004263133,0.00008518611,0.00016873647,0.00008749825,0.000078633835,0.000003226916,0.00006390725,0.00008973988,0.000003627811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001166983,0.00004536219,0.000005363948,0.000032975764,0.000011540739,9.3492524e-8,0.000121921235,0.0015087278,0.9964409,0.000025601088,0.0007248902,0.00096595],"study_design_scores_gemma":[0.00044043557,0.00016926344,0.000050119696,0.000039187784,0.00001443495,0.0000010413801,0.00017984063,0.0002451286,0.99689627,0.000042479747,0.0017990937,0.00012272576],"about_ca_topic_score_codex":0.0000018663806,"about_ca_topic_score_gemma":0.0000073017786,"teacher_disagreement_score":0.0022671942,"about_ca_system_score_codex":0.00000865288,"about_ca_system_score_gemma":0.000042432166,"threshold_uncertainty_score":0.34737888},"labels":[],"label_agreement":null},{"id":"W2025051882","doi":"10.1017/s1461145708008845","title":"Enhanced α1 adrenergic sensitivity in sensorimotor gating deficits in neonatal ventral hippocampus-lesioned rats","year":2008,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Prazosin; Prepulse inhibition; Internal medicine; Endocrinology; Agonist; Medicine; Oxidopamine; Hippocampus; Neuroscience; Antagonist; Receptor; Psychology; Schizophrenia (object-oriented programming); Dopamine; Dopaminergic","score_opus":0.014530919354829685,"score_gpt":0.27930762997531544,"score_spread":0.26477671062048574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025051882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964104,0.00027114802,0.00063666975,0.00042834703,0.0020800382,0.00009635269,0.000004020838,0.0000032323878,0.000069784386],"genre_scores_gemma":[0.9976075,0.0005306688,0.00025326372,0.0008556514,0.0006930877,0.0000035850076,0.0000055425317,0.000016915292,0.000033781544],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985557,0.00028944254,0.00047460705,0.00019496794,0.0002652459,0.00022002123],"domain_scores_gemma":[0.9992872,0.000087730594,0.00029332633,0.0000891955,0.00018309208,0.000059444552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044351202,0.00013731817,0.00018855101,0.00014168005,0.00004848236,0.000011691907,0.00032877453,0.00008172503,0.00006489449],"category_scores_gemma":[0.00009790565,0.000111844914,0.0001135216,0.000103529936,0.000063908796,0.00001264288,0.000078490586,0.0003342157,0.000004825582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011469284,0.0000782322,0.0008815075,0.0000018284844,0.000041715233,0.0008736307,0.00018129572,0.0047204993,0.99002546,0.00001740634,0.000110059824,0.0019214405],"study_design_scores_gemma":[0.0029703195,0.0003006832,0.015203363,0.000036556932,0.000011041784,0.002194559,0.000092854294,0.0007521002,0.97764766,0.00016596516,0.0004642555,0.00016062091],"about_ca_topic_score_codex":0.000012471103,"about_ca_topic_score_gemma":0.000026954975,"teacher_disagreement_score":0.014321856,"about_ca_system_score_codex":0.000042313255,"about_ca_system_score_gemma":0.00010531273,"threshold_uncertainty_score":0.45609033},"labels":[],"label_agreement":null},{"id":"W2025139420","doi":"10.1016/j.pharmthera.2009.04.001","title":"Pharmacological profiles of alpha 2 adrenergic receptor agonists identified using genetically altered mice and isobolographic analysis","year":2009,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute on Drug Abuse","keywords":"Alpha-2 adrenergic receptor; Alpha (finance); Pharmacology; Agonist; Adrenergic receptor; Receptor; β2 adrenergic receptor; Alpha-1B adrenergic receptor; Alpha-1A adrenergic receptor; Adrenergic; Biology; Chemistry; Endocrinology; Medicine; Beta-3 adrenergic receptor; Genetics","score_opus":0.06747052672864942,"score_gpt":0.3774997249217617,"score_spread":0.31002919819311225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025139420","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.036823645,0.9602215,0.0011392966,0.000029689454,0.0007318398,0.0008536809,0.00014336847,0.000028850289,0.000028092129],"genre_scores_gemma":[0.007693316,0.98730975,0.0029183174,0.000708436,0.0006268254,0.00007974203,0.0005092445,0.00007601486,0.000078352525],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960953,0.00087789516,0.0011058055,0.001052885,0.0002399514,0.0006281517],"domain_scores_gemma":[0.9983321,0.000097206714,0.00082539825,0.00033413016,0.00020608696,0.00020510012],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050758093,0.00074532465,0.0020438202,0.00045891732,0.0001721488,0.00004547483,0.00063403434,0.00097639865,0.00043506303],"category_scores_gemma":[0.000006773996,0.000643383,0.0010163797,0.00074675045,0.0004026215,0.000007122517,0.0002406759,0.00048391847,0.000004698004],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012992312,0.0002827249,0.000019636032,0.00081300654,0.012454312,0.000009056283,0.000024770854,0.00006652898,0.8338554,0.000022295417,0.00018651389,0.15213582],"study_design_scores_gemma":[0.001383769,0.0009536429,0.000017694998,0.0003682257,0.07389789,0.000086125634,0.00002404617,0.00082824065,0.20775141,0.000066784676,0.7132139,0.0014082434],"about_ca_topic_score_codex":0.000006537226,"about_ca_topic_score_gemma":0.0000022374911,"teacher_disagreement_score":0.7130274,"about_ca_system_score_codex":0.00003566547,"about_ca_system_score_gemma":0.00024276553,"threshold_uncertainty_score":0.9996017},"labels":[],"label_agreement":null},{"id":"W2025449906","doi":"10.1016/j.bpj.2012.11.3517","title":"Role of Post-M4 in the Gating of GLIC and ELIC","year":2013,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Allosteric regulation; Gating; Transmembrane domain; Chemistry; Biophysics; Mutation; Ion channel; Alanine; Biochemistry; Receptor; Biology; Amino acid; Gene","score_opus":0.005086450094266871,"score_gpt":0.21750890008719803,"score_spread":0.21242244999293117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025449906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.999477,0.0002155038,0.00006434817,0.000082114166,0.00001694127,0.000047958612,0.0000013306612,4.876426e-7,0.00009426899],"genre_scores_gemma":[0.999472,0.00004639138,0.0002737489,0.000059236492,0.00013809947,0.0000018994788,0.000001531041,0.0000039938386,0.000003072213],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995761,0.000043876655,0.00014641491,0.00006257651,0.000085521926,0.00008553392],"domain_scores_gemma":[0.9997487,0.000012206607,0.00008395903,0.00006692126,0.000060918563,0.000027310607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110519766,0.00004864668,0.00008420815,0.000016398613,0.000024392866,0.000013304839,0.0000966368,0.000037808855,0.000019527135],"category_scores_gemma":[0.000025622287,0.000030614978,0.00004890614,0.00003836775,0.00003445215,0.0000034151146,0.00002715088,0.0000762206,0.0000010008362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000768822,0.00003145992,0.0003573766,0.0000039327383,0.000008878,2.7848174e-7,0.000121174446,0.000004008953,0.9939848,0.0001777377,0.00001111042,0.005291547],"study_design_scores_gemma":[0.00016706354,0.0002775666,0.009892047,0.000017043896,0.000005855625,0.000020600055,0.00065214303,0.00016049905,0.9883147,0.00038514662,0.00006340117,0.000043933513],"about_ca_topic_score_codex":0.000030564926,"about_ca_topic_score_gemma":0.0000013514968,"teacher_disagreement_score":0.009534671,"about_ca_system_score_codex":0.0000014406208,"about_ca_system_score_gemma":0.000013083137,"threshold_uncertainty_score":0.12484425},"labels":[],"label_agreement":null},{"id":"W2025810459","doi":"10.1074/jbc.m407310200","title":"Agonist-dependent Dissociation of Human Somatostatin Receptor 2 Dimers","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"","keywords":"G protein-coupled receptor; Agonist; Förster resonance energy transfer; Receptor; Fluorescence recovery after photobleaching; Chemistry; Biophysics; Inverse agonist; Somatostatin receptor; HEK 293 cells; Cell biology; Photobleaching; Signal transduction; Biology; Biochemistry; Fluorescence","score_opus":0.014855009032513744,"score_gpt":0.2603232458763705,"score_spread":0.24546823684385677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025810459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998161,0.00037499057,0.0008960137,0.000086925684,0.00009609438,0.000041425083,0.000015684214,0.0000039200936,0.00032394245],"genre_scores_gemma":[0.99809575,0.00017208418,0.0012443375,0.000039716484,0.00028782358,0.0000015400045,0.000052568586,0.000009008748,0.000097146316],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900013,0.000031600375,0.00048192916,0.00014790178,0.00018002072,0.0001583899],"domain_scores_gemma":[0.99906844,0.000012463889,0.00055947097,0.00011057893,0.0001547205,0.00009430514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031176332,0.00012287687,0.0002354257,0.000014298541,0.000057519737,0.000012455199,0.00020098938,0.00024197891,0.00020393715],"category_scores_gemma":[0.000165749,0.00009169559,0.0002027337,0.00004632333,0.00006869814,0.0000041665166,0.000049972,0.00015248233,0.0000017194125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065576874,0.00010925025,0.000834942,0.000017504339,0.000053733584,0.000003474772,0.00003338774,0.00006389734,0.99835503,0.000044502216,0.000098906276,0.00031980316],"study_design_scores_gemma":[0.00065320695,0.00046614348,0.00030856582,0.000032351698,0.000013063111,0.000026093958,0.00024085464,5.2096067e-7,0.997018,0.00064387324,0.000485893,0.00011147943],"about_ca_topic_score_codex":0.000003817749,"about_ca_topic_score_gemma":3.7774328e-7,"teacher_disagreement_score":0.0013370678,"about_ca_system_score_codex":0.000039529714,"about_ca_system_score_gemma":0.000068319234,"threshold_uncertainty_score":0.37392375},"labels":[],"label_agreement":null},{"id":"W2025902121","doi":"10.1016/j.bmcl.2011.02.067","title":"The discovery and synthesis of potent zwitterionic inhibitors of renin","year":2011,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; hERG; Carboxylic acid; Drug discovery; CYP3A4; Renin inhibitor; Aryl; Renin–angiotensin system; Chemical synthesis; Combinatorial chemistry; Stereochemistry; In vitro; Enzyme; Biochemistry; Organic chemistry; Cytochrome P450","score_opus":0.008114779498595107,"score_gpt":0.1864860764926026,"score_spread":0.1783712969940075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025902121","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99780375,0.0010710744,0.00039451974,0.00038364762,0.000104854094,0.000062346335,0.000007099696,0.000004142875,0.0001685895],"genre_scores_gemma":[0.9991646,0.0003332903,0.00017684884,0.000091841226,0.0001496065,0.0000063004168,0.00000668047,0.000016008891,0.000054847693],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991045,0.000026856836,0.0003003991,0.00022178558,0.00017219642,0.00017425795],"domain_scores_gemma":[0.999418,0.00002589626,0.00018999947,0.00026984653,0.000035412988,0.000060819642],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002499845,0.00013702628,0.00017432019,0.000012326159,0.000059139362,0.000007360156,0.00019672558,0.00009176184,0.000033275355],"category_scores_gemma":[0.000115187024,0.00009576233,0.0000768134,0.000057610483,0.0002742927,0.000004241133,0.000088808614,0.000077640965,4.4943832e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007600833,0.000023549224,0.0005112069,0.000052762138,0.00005874024,0.0000023348532,0.000081422826,1.6240463e-7,0.9973327,0.000009310276,0.00028314526,0.0015686402],"study_design_scores_gemma":[0.00020067288,0.000057545538,0.00070728007,0.00007244742,0.000043999196,0.000023394983,0.0003064049,0.0000018021597,0.9981074,0.0000169868,0.0003602741,0.00010183464],"about_ca_topic_score_codex":0.000037130954,"about_ca_topic_score_gemma":0.0000012529684,"teacher_disagreement_score":0.0014668056,"about_ca_system_score_codex":0.000010191402,"about_ca_system_score_gemma":0.00004172468,"threshold_uncertainty_score":0.39050743},"labels":[],"label_agreement":null},{"id":"W2025932643","doi":"10.1074/jbc.m312407200","title":"RGS2 Binds Directly and Selectively to the M1 Muscarinic Acetylcholine Receptor Third Intracellular Loop to Modulate Gq/11α Signaling","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"RGS2; Heterotrimeric G protein; G protein; Regulator of G protein signaling; G protein-coupled receptor; Cell biology; GTPase-activating protein; Gq alpha subunit; Biology; Muscarinic acetylcholine receptor; GTPase; GTP-binding protein regulators; Chemistry; Signal transduction; Receptor; Biochemistry","score_opus":0.014370688447130514,"score_gpt":0.2408991204480991,"score_spread":0.2265284320009686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025932643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906427,0.0013289789,0.0064065233,0.0011624078,0.00016519992,0.00015739382,0.000013144219,0.000011832888,0.00011181455],"genre_scores_gemma":[0.99342024,0.00035258834,0.0043258374,0.0006667118,0.00097582367,0.000008794315,0.000014130333,0.000021700338,0.00021419265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840575,0.00006728408,0.00052259077,0.00040628124,0.0002222465,0.00037585894],"domain_scores_gemma":[0.99889714,0.000037716072,0.00024928525,0.00022596984,0.00024746876,0.00034241463],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079424307,0.000269395,0.00036027,0.000036138365,0.00014786962,0.0000671187,0.00042673474,0.00034427355,0.00009387158],"category_scores_gemma":[0.00043868707,0.00016959962,0.00019857255,0.00021368172,0.00006634069,0.000007906784,0.00020817634,0.0004151716,0.000009808741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002697991,0.000069143956,0.00012420227,0.000011682594,0.00008523321,0.000010974336,0.00007802907,0.0024871042,0.9948287,0.000008989285,0.00026129239,0.0017648347],"study_design_scores_gemma":[0.0005614144,0.00069721177,0.0001428935,0.0000602094,0.000024298457,0.00014749725,0.00014285505,0.00001521046,0.98793405,0.0001431066,0.009880519,0.00025075133],"about_ca_topic_score_codex":0.000006105705,"about_ca_topic_score_gemma":0.0000012515114,"teacher_disagreement_score":0.009619227,"about_ca_system_score_codex":0.00005629031,"about_ca_system_score_gemma":0.00009230729,"threshold_uncertainty_score":0.6916072},"labels":[],"label_agreement":null},{"id":"W2026103519","doi":"10.1152/ajpregu.00138.2012","title":"Restoration of renal function by a novel prostaglandin EP<sub>4</sub>receptor-derived peptide in models of acute renal failure","year":2012,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Theratechnologies (Canada); Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Renal function; Function (biology); Peptide; Internal medicine; Peptide receptor; Receptor; Medicine; Urology; Endocrinology; Chemistry; Biology; Biochemistry; Cell biology","score_opus":0.015512323784093618,"score_gpt":0.2489575183108738,"score_spread":0.23344519452678017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026103519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871931,0.0005001893,0.011832047,0.000031839965,0.00012394541,0.00020837008,0.00008204547,0.0000035596427,0.000024874813],"genre_scores_gemma":[0.9979587,0.00015446835,0.0014092607,0.00006471249,0.00021423452,0.00002199961,0.00014667971,0.00001793646,0.000011971395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978438,0.0004865689,0.00078937295,0.0003481517,0.00018313568,0.00034894983],"domain_scores_gemma":[0.9976889,0.00007170003,0.0014346736,0.00021106133,0.00046380045,0.00012989902],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003398896,0.0003518162,0.0010379008,0.000181497,0.00006789013,0.000006145676,0.00019284166,0.00016512987,0.000019188552],"category_scores_gemma":[0.000022487624,0.00026883173,0.00022183232,0.00023798524,0.00088042085,0.00007273081,0.00007482127,0.0003375854,9.874783e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025827195,0.00030869967,0.00026131203,0.000013463784,0.0005508981,1.473033e-7,0.0011721912,0.0010657301,0.9919599,0.0009937368,0.0007830996,0.00030807056],"study_design_scores_gemma":[0.0011478126,0.004585034,0.013492463,0.00009089953,0.00008382791,0.0000129708405,0.002251288,0.00031779177,0.9769117,0.0006824537,0.0001742318,0.00024949678],"about_ca_topic_score_codex":0.000031524,"about_ca_topic_score_gemma":0.000019880066,"teacher_disagreement_score":0.015048202,"about_ca_system_score_codex":0.000042224034,"about_ca_system_score_gemma":0.00013022388,"threshold_uncertainty_score":0.9999764},"labels":[],"label_agreement":null},{"id":"W2026192050","doi":"10.1139/y02-031","title":"NMR studies of CCK-8/CCK<sub>1</sub>complex support membrane-associated pathway for ligand-receptor interaction","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Receptor; Peptide; G protein-coupled receptor; Ligand (biochemistry); Chemistry; Biophysics; Cholecystokinin receptor; Membrane; Cholecystokinin; Stereochemistry; Biochemistry; Biology","score_opus":0.0369208274173958,"score_gpt":0.2854416528098209,"score_spread":0.24852082539242512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026192050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967995,0.0013308101,0.00005382099,0.00031549658,0.0012233641,0.0001472592,0.000086266955,0.0000023627213,0.0000410611],"genre_scores_gemma":[0.99751693,0.0011129315,0.000094179864,0.0006524272,0.00048045424,0.000010867116,0.0000512125,0.000017138242,0.000063860214],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988799,0.00014421652,0.00041802664,0.00019559714,0.000047441587,0.00031479407],"domain_scores_gemma":[0.998886,0.00008345748,0.00039618797,0.00006889449,0.00033659756,0.00022889434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002921921,0.00016353512,0.00041339383,0.00013178794,0.0001500513,0.00000590167,0.00014152058,0.00020973227,0.0006709191],"category_scores_gemma":[0.000088005596,0.0001503402,0.00015897509,0.00006357848,0.00019206494,0.0000120801715,0.000020700325,0.00017122505,0.000003360695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013198855,0.000043107022,0.00007538798,0.000058749043,0.000497556,0.000005866849,0.00028096462,0.00008564137,0.9825293,0.00003155565,0.014885172,0.0013747277],"study_design_scores_gemma":[0.0011927881,0.0012940131,0.00011901003,0.000017260323,0.00008715355,0.000042950618,0.00019037018,0.00008816633,0.9816447,0.00019971142,0.0149827385,0.00014112222],"about_ca_topic_score_codex":0.00002626616,"about_ca_topic_score_gemma":0.00033555776,"teacher_disagreement_score":0.001250906,"about_ca_system_score_codex":0.000034954854,"about_ca_system_score_gemma":0.00016708973,"threshold_uncertainty_score":0.73460937},"labels":[],"label_agreement":null},{"id":"W2026195537","doi":"10.1002/prp2.4","title":"Green fluorescent protein fused to peptide agonists of two dissimilar G protein‐coupled receptors: novel ligands of the bradykinin B<sub>2</sub> (rhodopsin family) receptor and parathyroid hormone <scp>PTH</scp><sub>1</sub> (secretin family) receptor","year":2013,"lang":"en","type":"article","venue":"Pharmacology Research & Perspectives","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; Université Laval","funders":"","keywords":"Internalization; G protein-coupled receptor; Receptor; Green fluorescent protein; Fusion protein; Parathyroid hormone; Agonist; HEK 293 cells; Parathyroid hormone receptor; Biology; Transfection; Cell biology; Biochemistry; Chemistry; Recombinant DNA; Hormone receptor; Calcium","score_opus":0.02483807847311671,"score_gpt":0.3022254399397686,"score_spread":0.2773873614666519,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026195537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885151,0.0040333923,0.00043169237,0.0011607229,0.00023088606,0.005303935,0.00014705611,0.000049730726,0.00012750027],"genre_scores_gemma":[0.9936574,0.0017264934,0.0015836922,0.00016935144,0.0006916504,0.0016497703,0.00007265355,0.00015269387,0.00029630182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99376184,0.0011100381,0.0009923255,0.0015745121,0.0010928347,0.0014684382],"domain_scores_gemma":[0.9962222,0.00026332063,0.0005072338,0.00080660614,0.0015454945,0.0006551597],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0022326515,0.00072340824,0.00092192536,0.00042762756,0.0005421241,0.00011012355,0.0011496651,0.00050573895,0.00006151753],"category_scores_gemma":[0.0009889798,0.00060624955,0.00036593032,0.0010086538,0.0013095348,0.000063984946,0.00106133,0.0010909293,0.00004697767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005783817,0.00074596866,0.00015333777,0.000109396075,0.00041340914,0.0000030074523,0.0023361095,0.000030366675,0.9825621,0.00013765022,0.01187547,0.0010547558],"study_design_scores_gemma":[0.0029087767,0.00204129,0.0019323133,0.00015702973,0.000057946483,0.000005719738,0.004080104,0.00022723676,0.9863073,0.00016863043,0.0017274286,0.0003861969],"about_ca_topic_score_codex":0.00026602665,"about_ca_topic_score_gemma":0.000033935292,"teacher_disagreement_score":0.010148041,"about_ca_system_score_codex":0.0002043546,"about_ca_system_score_gemma":0.0005768381,"threshold_uncertainty_score":0.9996389},"labels":[],"label_agreement":null},{"id":"W2026439530","doi":"10.1016/j.tips.2007.02.008","title":"Phosphorylation-independent attenuation of GPCR signalling","year":2007,"lang":"en","type":"review","venue":"Trends in Pharmacological Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"Phosphorylation; Signalling; Attenuation; G protein-coupled receptor; Neuroscience; Psychology; Cell biology; Computational biology; Signal transduction; Chemistry; Biology; Physics","score_opus":0.13538201865720867,"score_gpt":0.4274491928778931,"score_spread":0.29206717422068446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026439530","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022872866,0.9944014,0.0006989234,0.00000724798,0.0003394756,0.0001867381,0.000010903341,0.000008605376,0.0020594017],"genre_scores_gemma":[0.021177584,0.9774213,0.00083760504,0.000032204956,0.00020482094,0.000029912451,0.00008023468,0.000010550647,0.00020582808],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980849,0.00014864736,0.00060026126,0.0005161825,0.00034256518,0.0003074449],"domain_scores_gemma":[0.99938744,0.00007759842,0.0003446322,0.00008292257,0.000038799946,0.00006859694],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014208085,0.00023217835,0.00055528467,0.00024709606,0.000082271974,0.000021162246,0.0004501951,0.0003349093,0.0010417119],"category_scores_gemma":[0.00003559842,0.00016360712,0.00026198325,0.0006932779,0.00016669428,0.000005391549,0.00010957187,0.0002023187,0.00000648672],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010015722,0.00007503449,0.000023937075,0.00013963874,0.000030837447,0.0000041461212,0.00001049982,0.0002316802,0.011156066,0.00011559545,0.000104473555,0.9880981],"study_design_scores_gemma":[0.0006046805,0.000946774,0.00004727167,0.0012071825,0.00035122305,0.000015965217,0.00005656347,0.0003373518,0.051015217,0.00026386764,0.9442896,0.0008642665],"about_ca_topic_score_codex":0.000011665004,"about_ca_topic_score_gemma":0.0000074063437,"teacher_disagreement_score":0.9872338,"about_ca_system_score_codex":0.000035368525,"about_ca_system_score_gemma":0.00009134784,"threshold_uncertainty_score":0.9998715},"labels":[],"label_agreement":null},{"id":"W2026743859","doi":"10.1038/sj.mp.4001897","title":"Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine","year":2006,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":207,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Fluoxetine; Antidepressant; Monoaminergic; Pharmacology; Imipramine; Sleep deprivation; Reuptake inhibitor; Medicine; Reuptake; Phenelzine; Serotonin reuptake inhibitor; Serotonin; Psychology; Serotonin transporter; Citalopram; Internal medicine; Circadian rhythm; Hippocampus; Biology; Monoamine oxidase","score_opus":0.00789604278476836,"score_gpt":0.2099183518437126,"score_spread":0.20202230905894425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026743859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9265791,0.02436933,0.046707254,0.0013649258,0.00040114395,0.00035035494,0.0000058567625,0.000019624626,0.00020237191],"genre_scores_gemma":[0.9965526,0.0007474328,0.0014766542,0.0005320459,0.00036495263,0.00006190887,0.00016204677,0.000038911014,0.00006348875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988705,0.000070487884,0.00018295298,0.00042178636,0.0001899811,0.00026429107],"domain_scores_gemma":[0.99952394,0.0000073861893,0.00008421889,0.00030016946,0.000041700725,0.000042585445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119987366,0.0002203473,0.00014524345,0.000042460408,0.00022457204,0.000058171743,0.00015389301,0.000108931024,0.000017377697],"category_scores_gemma":[0.0000037326831,0.00016798475,0.00015275805,0.00009363351,0.000046362984,0.0000057064663,0.000026476906,0.000093563605,0.000002061375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008740529,0.00007403047,0.006842752,0.0000043382047,0.00013376497,0.000009136108,0.000016694687,0.00004431904,0.98585474,0.0035668507,0.0004834186,0.002882524],"study_design_scores_gemma":[0.0028628623,0.00059767975,0.025957491,0.00003584903,0.00008504417,0.0000951585,0.00008476169,0.00015227517,0.94555587,0.008045714,0.016012417,0.00051488174],"about_ca_topic_score_codex":0.00003278343,"about_ca_topic_score_gemma":0.000039285755,"teacher_disagreement_score":0.06997342,"about_ca_system_score_codex":0.000009927737,"about_ca_system_score_gemma":0.000024781142,"threshold_uncertainty_score":0.68502194},"labels":[],"label_agreement":null},{"id":"W2026782203","doi":"10.1159/000159223","title":"Multiple Mechanisms of Activating Ca <sup>2+</sup> Entry in Freshly Isolated Rabbit Aortic Endothelial Cells","year":2008,"lang":"en","type":"article","venue":"Journal of Vascular Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cyclopiazonic acid; Thapsigargin; Endoplasmic reticulum; Intracellular; Dantrolene; Channel blocker; Muscarinic acetylcholine receptor; Acetylcholine; Chemistry; Receptor; Endocrinology; Internal medicine; Biophysics; Cell biology; Biology; Biochemistry; Calcium; Medicine","score_opus":0.027775159391092395,"score_gpt":0.28874059663630625,"score_spread":0.26096543724521387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026782203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839804,0.00066852116,0.0148892505,0.000032997785,0.0000909899,0.0002133563,0.000010036308,0.000002667415,0.000111758796],"genre_scores_gemma":[0.995052,0.0009358112,0.0034919987,0.000024385628,0.00024090722,0.0000055319147,0.000007836077,0.00003557619,0.00020596513],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971827,0.00048070797,0.00069031335,0.0002569496,0.00090055505,0.00048871915],"domain_scores_gemma":[0.9986354,0.000107811866,0.00024312838,0.0003078799,0.00054233184,0.0001634635],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002160959,0.00016289187,0.00037798486,0.00033572371,0.00013406087,0.000022601223,0.00042380713,0.00023030529,0.0002281838],"category_scores_gemma":[0.00055985706,0.00014247204,0.00032829127,0.00031271577,0.00008701259,0.000017508113,0.00015448888,0.00062744255,0.000011602712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030056917,0.00019029224,0.00033610858,0.00003627363,0.00014266866,0.00007781458,0.00043534904,0.004826792,0.9926312,0.000017097424,0.00028620972,0.0007196426],"study_design_scores_gemma":[0.0019586566,0.0008474781,0.00007360737,0.00010896966,0.00001021421,0.00008054556,0.0006047281,0.0071763853,0.9870489,0.00023804649,0.0017133204,0.00013912501],"about_ca_topic_score_codex":0.00013258863,"about_ca_topic_score_gemma":0.000007345869,"teacher_disagreement_score":0.011397252,"about_ca_system_score_codex":0.000056950998,"about_ca_system_score_gemma":0.0003150451,"threshold_uncertainty_score":0.5809841},"labels":[],"label_agreement":null},{"id":"W2026851494","doi":"10.1016/s0021-9673(99)00906-1","title":"Simultaneous separation of angiotensin and endothelin peptide families by high-performance liquid chromatography: application to the specific radioimmunoassay measurement of angiotensin II or endothelin-1 from tissue","year":2000,"lang":"en","type":"article","venue":"Journal of Chromatography A","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Heart and Stroke Foundation of Canada","keywords":"Angiotensin II; Chemistry; Radioimmunoassay; High-performance liquid chromatography; Angiotensin III; Chromatography; Endothelin receptor; Ventricle; Renin–angiotensin system; Peptide hormone; Endothelin 1; Internal medicine; Peptide; Angiotensin 1; Endothelins; Endocrinology; Angiotensin II receptor type 1; Biochemistry; Receptor; Blood pressure; Biology; Medicine","score_opus":0.006444969819176595,"score_gpt":0.21863113321961672,"score_spread":0.21218616340044014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026851494","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9826909,0.008511717,0.008066146,0.0001598341,0.000097274264,0.00033867144,0.00010252452,0.000007084437,0.00002586519],"genre_scores_gemma":[0.98947936,0.005496392,0.004626501,0.00009069968,0.0002148294,0.000007576842,0.000026134274,0.000027876084,0.000030606618],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99818856,0.0001067471,0.00078160584,0.00024859695,0.00046993015,0.0002045629],"domain_scores_gemma":[0.9986067,0.000045959314,0.00052645814,0.00035058512,0.00038205113,0.0000882349],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052661996,0.00023237169,0.0004328912,0.00017051541,0.00012862521,0.0000230658,0.0002639359,0.00013918556,0.0000681902],"category_scores_gemma":[0.00002823663,0.0001627599,0.00020533266,0.0002824787,0.00011521335,0.000017934282,0.000033205935,0.00011379614,0.0000016802865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010777316,0.000111208035,0.0000910894,0.000017095374,0.00024267985,0.0000027971603,0.00030467354,0.0014353427,0.98291236,0.0000067374667,0.00097342074,0.012824868],"study_design_scores_gemma":[0.00077888905,0.0021053862,0.00033702503,0.00013231045,0.00007550522,0.000068706315,0.00011469924,0.00024531863,0.95962983,0.000019547379,0.036315564,0.00017721248],"about_ca_topic_score_codex":0.00009878392,"about_ca_topic_score_gemma":0.000019059422,"teacher_disagreement_score":0.035342146,"about_ca_system_score_codex":0.000013592867,"about_ca_system_score_gemma":0.00005758371,"threshold_uncertainty_score":0.6637156},"labels":[],"label_agreement":null},{"id":"W2026954352","doi":"10.1139/y03-020","title":"Activation of sarcolemma and nuclear membranes ET-1 receptors regulates transcellular calcium levels in heart and vascular smooth muscle cells","year":2003,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Sarcolemma; Cytosol; Receptor; Vascular smooth muscle; Cell biology; Chemistry; Biology; Biophysics; Myocyte; Endocrinology; Biochemistry","score_opus":0.014718764628729493,"score_gpt":0.24128964009983142,"score_spread":0.22657087547110194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026954352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978366,0.0015775948,0.000035993402,0.00021596315,0.0002141476,0.00008831845,0.000006100158,8.0039615e-7,0.000024519257],"genre_scores_gemma":[0.9987417,0.0005203558,0.0002732935,0.0003833064,0.000053373235,0.0000012916151,0.00000329292,0.000012022851,0.000011393291],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999104,0.00027680918,0.00023164078,0.00016660575,0.00003403477,0.00018690656],"domain_scores_gemma":[0.99957633,0.000033209046,0.00010446741,0.00005297492,0.000056492285,0.0001765085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003656969,0.00011101535,0.00024766263,0.00011481469,0.00006436127,0.000005873961,0.00005520381,0.00017551679,0.00035996336],"category_scores_gemma":[0.000017206617,0.00010607376,0.00004795652,0.000053119675,0.00018187199,0.000011720377,0.000007755351,0.0001517936,1.8692614e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034522367,0.000014268426,0.00015882477,0.00005619729,0.000046120844,0.00000247071,0.00034688655,0.00013506779,0.998662,0.00016677842,0.00014885828,0.00022798221],"study_design_scores_gemma":[0.0008737796,0.00031801616,0.0035153923,0.00001796271,0.000028254097,0.000012814961,0.00016277115,0.000032401826,0.9678214,0.00039152263,0.026719522,0.0001061366],"about_ca_topic_score_codex":0.00021553025,"about_ca_topic_score_gemma":0.00013905858,"teacher_disagreement_score":0.030840596,"about_ca_system_score_codex":0.000008980161,"about_ca_system_score_gemma":0.00014889808,"threshold_uncertainty_score":0.43255624},"labels":[],"label_agreement":null},{"id":"W2027056512","doi":"10.1080/10799890801941889","title":"G Protein-Coupled Receptors in and on the Cell Nucleus: A New Signaling Paradigm?","year":2008,"lang":"en","type":"review","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Endosome; Endoplasmic reticulum; Golgi apparatus; Nucleus; Cell biology; Biology; Receptor; Signal transduction; Neuroscience; Cell signaling; Genetics","score_opus":0.02411345829378884,"score_gpt":0.2533908441657804,"score_spread":0.22927738587199156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027056512","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.040366273,0.957176,0.0010148272,0.00011816545,0.0006058545,0.00067201245,0.000004997153,0.0000054491834,0.00003639525],"genre_scores_gemma":[0.004892775,0.9931575,0.0005487263,0.00003264411,0.0009764739,0.000015896601,0.000014825958,0.00006593225,0.00029522303],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977002,0.00032713063,0.0009479443,0.00040899028,0.00031861025,0.00029712723],"domain_scores_gemma":[0.99880034,0.00008037436,0.0006907229,0.00016334454,0.00006418132,0.00020101223],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006354225,0.00047034406,0.0009966916,0.0002445311,0.00015497612,0.000074535,0.00022140615,0.0004703268,0.00023459984],"category_scores_gemma":[0.00003788173,0.00030507668,0.00045947338,0.00026070685,0.000095971416,0.000018295488,0.000023204942,0.0007187011,0.0000023447149],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006050379,0.00026167813,0.000012560424,0.0019038122,0.00042846886,0.00003468896,0.00092078064,0.00015638492,0.051450472,0.00014246165,0.0024342043,0.94164944],"study_design_scores_gemma":[0.0007883528,0.0014758654,7.704741e-7,0.004366936,0.00017148063,0.00033780662,0.0002142077,0.00001012823,0.018233677,0.00014569212,0.9737512,0.0005039086],"about_ca_topic_score_codex":0.000012884966,"about_ca_topic_score_gemma":0.0000017769166,"teacher_disagreement_score":0.971317,"about_ca_system_score_codex":0.00004906769,"about_ca_system_score_gemma":0.00027372324,"threshold_uncertainty_score":0.99994016},"labels":[],"label_agreement":null},{"id":"W2027252687","doi":"10.1074/jbc.m114.593178","title":"Mapping the Putative G Protein-coupled Receptor (GPCR) Docking Site on GPCR Kinase 2","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"G protein-coupled receptor kinase; G protein-coupled receptor; Beta adrenergic receptor kinase; Biology; Protein kinase domain; Arrestin; Receptor; Kinase; Cell biology; Phosphorylation; Allosteric regulation; Rhodopsin-like receptors; Biochemistry; Agonist; Metabotropic receptor","score_opus":0.021812065016419236,"score_gpt":0.23898582979362215,"score_spread":0.2171737647772029,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027252687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940562,0.00035106498,0.00424602,0.00036938643,0.00013717654,0.000119108,0.000006596083,0.000008513095,0.00070591917],"genre_scores_gemma":[0.996934,0.00007376665,0.0011301747,0.00037726553,0.0012229438,0.00000957306,0.00002665501,0.00001536622,0.00021027373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864155,0.00013048916,0.00045202684,0.00027244005,0.0002204461,0.00028304133],"domain_scores_gemma":[0.99890906,0.00007734487,0.00048007656,0.0002197329,0.00018338408,0.00013037736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008849031,0.0002176347,0.00027957413,0.000020957674,0.00015461679,0.00004882609,0.00035772217,0.00027361148,0.00024595472],"category_scores_gemma":[0.00068203034,0.00012317758,0.00026482446,0.00009647413,0.00010087415,0.000004935081,0.00007698377,0.00039964274,0.000011882258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017673471,0.000055428223,0.00013723574,0.00001591219,0.00005067098,0.000005802448,0.000051348004,0.00014904687,0.9971136,0.000027570053,0.00021766526,0.0019989808],"study_design_scores_gemma":[0.00048379053,0.00055841875,0.00011336722,0.0000790313,0.000007958707,0.000040362076,0.00022213905,0.00015816823,0.9809194,0.00033034707,0.01690248,0.00018452686],"about_ca_topic_score_codex":0.0000016300305,"about_ca_topic_score_gemma":1.3636092e-7,"teacher_disagreement_score":0.016684813,"about_ca_system_score_codex":0.000029546492,"about_ca_system_score_gemma":0.000042827498,"threshold_uncertainty_score":0.5023036},"labels":[],"label_agreement":null},{"id":"W2027284421","doi":"10.1016/j.cellsig.2014.05.009","title":"Nodal signals via β-arrestins and RalGTPases to regulate trophoblast invasion","year":2014,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Trophoblast; Cytotrophoblast; Nodal signaling; Placentation; Biology; Cell biology; NODAL; Choriocarcinoma; Cancer research; Placenta; Anatomy; Embryo; Embryogenesis; Genetics","score_opus":0.008134161900420614,"score_gpt":0.2042323923967683,"score_spread":0.19609823049634767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027284421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.68411285,0.0004454644,0.31496778,0.00005077043,0.00013235291,0.00015104917,0.0000024617518,0.000021245962,0.00011603355],"genre_scores_gemma":[0.99232477,0.00004865427,0.0062803663,0.00035957198,0.0005452869,0.000015285734,0.00005537793,0.000050823357,0.00031984036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984801,0.0001088456,0.0002908898,0.0005619301,0.00019188323,0.00036639307],"domain_scores_gemma":[0.9992621,0.000034538723,0.000090750094,0.000275416,0.00008008578,0.00025711764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004361492,0.00024721658,0.00023626097,0.000077150755,0.00019443045,0.0000765522,0.00019375191,0.00016369276,0.00012009261],"category_scores_gemma":[0.00009069609,0.00023784064,0.00009874702,0.00010451574,0.000042964282,0.000006562295,0.0001470862,0.000106434316,0.00003492153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061537605,0.000022515342,0.00009665802,0.000021870832,0.000020370237,0.0000051214015,0.000047526035,0.0026638568,0.9931355,0.00010733256,0.00010884202,0.0037088732],"study_design_scores_gemma":[0.00036773225,0.00044708338,0.00003744391,0.000066757035,0.000021545204,0.000009741931,0.00002487957,0.0045915325,0.9855255,0.00044978663,0.008132974,0.00032503527],"about_ca_topic_score_codex":0.000015673651,"about_ca_topic_score_gemma":0.000005553618,"teacher_disagreement_score":0.30868742,"about_ca_system_score_codex":0.0000102081085,"about_ca_system_score_gemma":0.000024149687,"threshold_uncertainty_score":0.969886},"labels":[],"label_agreement":null},{"id":"W2027326213","doi":"10.1530/jme-15-0081","title":"Go protein subunit Goα and the secretory process of the natriuretic peptide hormones ANF and BNP","year":2015,"lang":"en","type":"article","venue":"Journal of Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Ottawa","funders":"Heart and Stroke Foundation of Canada","keywords":"Internal medicine; Endocrinology; Atrial natriuretic peptide; Immunoprecipitation; Immunocytochemistry; Protein subunit; Chemistry; Gene isoform; Hormone; Brain natriuretic peptide; Granule (geology); Biology; Cell biology; Heart failure; Medicine; Biochemistry; Gene","score_opus":0.008184379309216538,"score_gpt":0.22910483918113522,"score_spread":0.2209204598719187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027326213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867855,0.010921741,0.0008439666,0.0008541995,0.000117812466,0.00021179786,0.0000021394033,0.0000020028713,0.00026085493],"genre_scores_gemma":[0.9988564,0.0003246539,0.00043878137,0.00016125714,0.00009072769,0.000007372929,0.0000010352667,0.000015134066,0.000104602135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887705,0.00025681366,0.00032509604,0.0001448183,0.00019978643,0.00019644997],"domain_scores_gemma":[0.9990794,0.000019788042,0.0003430512,0.00019922025,0.0002777541,0.00008079341],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038869638,0.00013344771,0.0002538485,0.000048347167,0.000056055444,0.000016314696,0.00027149974,0.00009678445,0.0000052629616],"category_scores_gemma":[0.0002850375,0.00007552627,0.000104297855,0.000071110866,0.0003539052,0.000006250179,0.00014496825,0.00022709723,3.4811427e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041227552,0.000026118214,0.00040674486,0.000035063036,0.00012781523,0.000030992454,0.00028598515,0.00007500517,0.99521154,0.0023154174,0.00015554047,0.0009174801],"study_design_scores_gemma":[0.002809447,0.00072121376,0.00026424156,0.000042081923,0.00009298182,0.0013378179,0.0009516887,0.000060241608,0.9844238,0.0044234665,0.004736095,0.00013692092],"about_ca_topic_score_codex":0.000009640917,"about_ca_topic_score_gemma":0.000003998524,"teacher_disagreement_score":0.01207095,"about_ca_system_score_codex":0.000008032519,"about_ca_system_score_gemma":0.00013789408,"threshold_uncertainty_score":0.3079872},"labels":[],"label_agreement":null},{"id":"W2027602369","doi":"10.2174/138945006779025400","title":"Susceptibility Genes for the Side Effect of Antipsychotics on Body Weight and Obesity","year":2006,"lang":"en","type":"review","venue":"Current Drug Targets","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; SNC-Lavalin (Canada)","funders":"","keywords":"Antipsychotic; Obesity; Allele; Phenotype; Medicine; Schizophrenia (object-oriented programming); Genetics; Adverse effect; Gene; Psychiatry; Biology; Internal medicine; Bioinformatics","score_opus":0.020286388191482315,"score_gpt":0.32326645319012365,"score_spread":0.30298006499864133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027602369","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004310746,0.99188006,0.0010787888,0.0000052100677,0.0012118903,0.0012965549,0.00019049269,0.000007503783,0.000018781566],"genre_scores_gemma":[0.0025378887,0.9959913,0.00011612395,0.000004773682,0.0006100298,0.00008154271,0.0005421349,0.000040008046,0.00007623507],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99842757,0.00021190103,0.00042293803,0.0005386263,0.00014129208,0.0002576831],"domain_scores_gemma":[0.9988607,0.00022028397,0.00030340636,0.00049165386,0.000065680106,0.000058235702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062098977,0.00040175268,0.0008492468,0.000040050178,0.00012643657,0.000020889433,0.0002741083,0.00020772078,0.000008230935],"category_scores_gemma":[0.00007284485,0.00023827278,0.00054423406,0.000056465557,0.0000826709,0.0000018131401,0.000089414854,0.00017648062,0.0000022290853],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010599784,0.00019468176,0.00024792997,0.018585138,0.0002568533,6.52226e-7,0.000012396346,0.0000057487664,0.0033117044,0.000110911555,0.0057261367,0.97144186],"study_design_scores_gemma":[0.00028255495,0.00028539344,0.000021406186,0.0011033748,0.00047504774,0.0000021119506,0.0000015618845,0.000030356166,0.01941278,0.000053069107,0.97805816,0.0002741743],"about_ca_topic_score_codex":0.000003535874,"about_ca_topic_score_gemma":0.000008592905,"teacher_disagreement_score":0.97233206,"about_ca_system_score_codex":0.000014702532,"about_ca_system_score_gemma":0.000056137535,"threshold_uncertainty_score":0.9716482},"labels":[],"label_agreement":null},{"id":"W2027660679","doi":"10.1139/y02-045","title":"Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors","year":2002,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":102,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Cell biology; G protein-coupled receptor kinase; G protein-coupled receptor; MAPK7; MAP kinase kinase kinase; ASK1; Mitogen-activated protein kinase; Biology; MAP2K7; c-Raf; Mitogen-activated protein kinase kinase; Receptor tyrosine kinase; Proto-oncogene tyrosine-protein kinase Src; Protein kinase C; MAPK14; Cyclin-dependent kinase 9; Protein kinase A; Kinase; Signal transduction; Cyclin-dependent kinase 2","score_opus":0.018408409902046355,"score_gpt":0.27075146407034945,"score_spread":0.2523430541683031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027660679","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1803442,0.81868285,0.000033151115,0.000029926838,0.0004724113,0.00037711047,0.000048511312,0.0000017632306,0.000010089667],"genre_scores_gemma":[0.1076207,0.8911089,0.00015293401,0.00007228741,0.0005685111,0.000031445663,0.00017417231,0.000046819,0.00022427774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839014,0.00036334433,0.00058714126,0.00029260124,0.0000557239,0.00031105246],"domain_scores_gemma":[0.9985476,0.00004330446,0.000871638,0.000086385815,0.00015471641,0.0002963705],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000242088,0.00030182383,0.00093504286,0.00018805871,0.00012851303,0.000009305636,0.00018379424,0.00054968207,0.0009701749],"category_scores_gemma":[0.00007451738,0.00026102734,0.00017403363,0.00010716548,0.00021775303,0.00001041979,0.00003154803,0.0003937044,8.7707656e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041618143,0.000014722394,0.0000013409625,0.0012823769,0.0003103691,0.0000042093243,0.00003377821,0.000001573071,0.96970224,0.000008227905,0.0028748917,0.025724657],"study_design_scores_gemma":[0.00031288766,0.00039655555,4.0406644e-7,0.0004548452,0.00013853669,0.000027209033,0.000016756057,0.0000029797288,0.5891316,0.000033124972,0.4093088,0.00017631399],"about_ca_topic_score_codex":0.00022071015,"about_ca_topic_score_gemma":0.00002119264,"teacher_disagreement_score":0.40643388,"about_ca_system_score_codex":0.000031635875,"about_ca_system_score_gemma":0.00045568848,"threshold_uncertainty_score":0.9999842},"labels":[],"label_agreement":null},{"id":"W2027689184","doi":"10.1074/jbc.m414071200","title":"Involvement of Actin in Agonist-induced Endocytosis of the G Protein-coupled Receptor for Thromboxane A2","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Sherbrooke","funders":"","keywords":"Endocytosis; Agonist; Actin; Cell biology; Thromboxane A2; Receptor; Chemistry; Receptor-mediated endocytosis; Thromboxane; Internal medicine; Medicine; Biology; Biochemistry; Platelet","score_opus":0.03059700511962465,"score_gpt":0.26546569242246637,"score_spread":0.23486868730284172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027689184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988471,0.00028479888,0.00021171462,0.00023015741,0.000058632024,0.00028169365,0.000014448607,0.0000014815936,0.00006994059],"genre_scores_gemma":[0.99692017,0.00008526057,0.0025514252,0.000047457022,0.00028888645,0.000022287142,0.000009869484,0.000008583824,0.00006606797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99881774,0.000042052347,0.0006426289,0.0001622111,0.00015404023,0.00018134055],"domain_scores_gemma":[0.9988874,0.0000326006,0.0006711541,0.00017995182,0.00017364064,0.0000552047],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004740583,0.0001355718,0.00033201714,0.000016215374,0.000029982577,0.0000059807085,0.00034087506,0.00023717505,0.00014669224],"category_scores_gemma":[0.000287641,0.00008240334,0.00029517183,0.00007661351,0.00006617129,0.000004131814,0.00008276334,0.00016600169,2.2942235e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002902471,0.000196179,0.00039638896,0.00005613483,0.00004828519,3.2869497e-7,0.00002383615,0.000031799093,0.99792755,0.000011505276,0.00006577206,0.00095199066],"study_design_scores_gemma":[0.00092310575,0.0005055904,0.00017981234,0.00009407802,0.000011605992,0.0000068651084,0.0001494476,0.000020533005,0.9959969,0.000077060715,0.0019394435,0.000095555224],"about_ca_topic_score_codex":0.000004413834,"about_ca_topic_score_gemma":0.000002152959,"teacher_disagreement_score":0.0023397107,"about_ca_system_score_codex":0.00003565969,"about_ca_system_score_gemma":0.00010145774,"threshold_uncertainty_score":0.33603108},"labels":[],"label_agreement":null},{"id":"W2028276524","doi":"10.1016/j.mcn.2012.09.006","title":"C-terminal processing of the teneurin proteins: Independent actions of a teneurin C-terminal associated peptide in hippocampal cells","year":2012,"lang":"en","type":"article","venue":"Molecular and Cellular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Biology; Hippocampal formation; Cell biology; Membrane protein; Neuroscience; Genetics; Membrane","score_opus":0.014103426894563401,"score_gpt":0.23657444400093042,"score_spread":0.22247101710636702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028276524","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965765,0.00031001068,0.0025802313,0.000016825028,0.00016510522,0.00026468642,0.000007543346,0.000004198257,0.00007492507],"genre_scores_gemma":[0.99955446,0.000015375115,0.00019386208,0.00007765123,0.000024868901,0.000017828903,0.0000030414249,0.0000159997,0.000096937256],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985945,0.00015107908,0.0002963636,0.00031384005,0.00031257293,0.00033163573],"domain_scores_gemma":[0.9993959,0.0000058068654,0.00021356012,0.0002467267,0.000051643914,0.0000863322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035736914,0.00015765107,0.00017286606,0.000066638466,0.00009789823,0.000022575938,0.0002832741,0.00010083915,0.000005153375],"category_scores_gemma":[0.00008044405,0.00012643874,0.00009944899,0.00025138602,0.00018107762,0.000017439925,0.0001933851,0.00015541966,2.6960643e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016408942,0.00016687377,0.007113872,0.0000387104,0.0000023486186,0.000011171984,0.000093626055,0.00011455524,0.9918794,0.000016320904,0.0000019534145,0.0005447302],"study_design_scores_gemma":[0.00024556083,0.0001594129,0.009603218,0.0000542586,0.000015498126,0.000040829604,0.00006582157,0.00022897957,0.98932797,0.000028768778,0.00009980261,0.0001298628],"about_ca_topic_score_codex":0.000020349731,"about_ca_topic_score_gemma":0.0000054101884,"teacher_disagreement_score":0.0029779607,"about_ca_system_score_codex":0.000010883345,"about_ca_system_score_gemma":0.00008283107,"threshold_uncertainty_score":0.5156022},"labels":[],"label_agreement":null},{"id":"W2028280475","doi":"10.1016/s0006-8993(00)02414-8","title":"The involvement of ventral tegmental area cholinergic muscarinic receptors in classically conditioned fear expression as measured with fear-potentiated startle","year":2000,"lang":"en","type":"article","venue":"Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Ventral tegmental area; Neuroscience; Muscarinic acetylcholine receptor; Psychology; Amygdala; Acetylcholine; Moro reflex; Fear conditioning; Cholinergic; Classical conditioning; Dopamine; Startle response; Reflex; Endocrinology; Internal medicine; Receptor; Medicine; Dopaminergic; Conditioning","score_opus":0.030944451001007782,"score_gpt":0.3054663334503138,"score_spread":0.27452188244930603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028280475","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978036,0.00023311524,0.000040034847,0.00039078487,0.00004924194,0.00040990717,0.000012543238,0.000007339811,0.0010533895],"genre_scores_gemma":[0.9965469,0.0002703493,0.0001565887,0.00006398838,0.00006239527,0.00006578755,0.00019043662,0.000022696719,0.0026208267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99789244,0.00041067525,0.00026936983,0.00034226314,0.00064765615,0.00043761844],"domain_scores_gemma":[0.9992828,0.000063446714,0.000054637818,0.0003130162,0.00015221052,0.0001339145],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012391637,0.00012715298,0.00014228314,0.000071049086,0.00021643421,0.000047700483,0.00027558478,0.0001290589,0.0011170686],"category_scores_gemma":[0.00013231642,0.00008740765,0.000068445996,0.00024404046,0.00019533317,0.000008721655,0.00008179735,0.00026112434,0.000014455667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008059929,0.00016614272,0.00047808758,0.000011078682,0.00003345981,0.0000073173906,0.0001227086,0.00030699818,0.9931167,0.00005210068,0.0024594646,0.0024399436],"study_design_scores_gemma":[0.0017940407,0.0011295903,0.001248255,0.00010434792,0.0000042666115,0.000004332593,0.00089962455,0.00017881983,0.97745407,0.00018023168,0.016848123,0.00015432236],"about_ca_topic_score_codex":0.000109849294,"about_ca_topic_score_gemma":0.00015224102,"teacher_disagreement_score":0.015662659,"about_ca_system_score_codex":0.000048194746,"about_ca_system_score_gemma":0.00020569579,"threshold_uncertainty_score":0.99979603},"labels":[],"label_agreement":null},{"id":"W2028771760","doi":"10.1016/j.ejphar.2007.08.027","title":"Differential desensitization of dopamine D2 receptor isoforms by protein kinase C: The importance of receptor phosphorylation and pseudosubstrate sites","year":2007,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Protein kinase C; Dopamine; Receptor; Dopamine receptor; Phosphorylation; Biology; Dopamine receptor D2; Desensitization (medicine); Cell biology; Internal medicine; Endocrinology; Molecular biology; Chemistry; Biochemistry","score_opus":0.008961262844343404,"score_gpt":0.24512543811320434,"score_spread":0.23616417526886094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028771760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98301464,0.0008107671,0.015605257,0.0001132227,0.00024145606,0.00015085541,0.000010835511,0.000002023244,0.000050941264],"genre_scores_gemma":[0.998124,0.00028892772,0.0010655894,0.000066772925,0.00030332856,6.563772e-7,0.000027960788,0.000020341373,0.00010241319],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988189,0.00021117262,0.00056891644,0.0001255397,0.00012702435,0.0001485005],"domain_scores_gemma":[0.99886113,0.000024316278,0.00074762106,0.000073410105,0.00023333357,0.000060186263],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00092815387,0.00011518187,0.00017706984,0.000047293244,0.000051002546,0.000007734994,0.00013451421,0.000044747077,0.00026922597],"category_scores_gemma":[0.000049938917,0.00008164805,0.00007104674,0.00007661058,0.000110080844,0.000008613687,0.00004330787,0.00012543323,0.0000011552412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053660065,0.000063978616,0.0010377418,0.000020537671,0.00006970955,0.0000044191033,0.00008183201,0.000028144377,0.99305266,0.000017872571,0.0012836998,0.003802815],"study_design_scores_gemma":[0.00091300526,0.0007852467,0.0006455449,0.000019509915,0.000037069814,0.000020535124,0.000093789946,0.000048286776,0.99437463,0.000008898426,0.002972122,0.000081370206],"about_ca_topic_score_codex":0.0000011764731,"about_ca_topic_score_gemma":0.00000116861,"teacher_disagreement_score":0.015109368,"about_ca_system_score_codex":0.000008962815,"about_ca_system_score_gemma":0.000025742209,"threshold_uncertainty_score":0.3329511},"labels":[],"label_agreement":null},{"id":"W2028818820","doi":"10.1007/s00360-005-0029-8","title":"ANG II-induced attenuation of duck salt gland secretion does not depend upon the release of adrenal catecholamines","year":2005,"lang":"en","type":"article","venue":"Journal of Comparative Physiology B","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; Toronto Zoo; University of Toronto","funders":"","keywords":"Endocrinology; Internal medicine; Salt gland; Catecholamine; Mineralocorticoid; Chemistry; Saline; Adrenal gland; Dexamethasone; Angiotensin II; Secretion; Aldosterone; Blood pressure; Secretion rate; Medicine","score_opus":0.02180381239703943,"score_gpt":0.2859923066988789,"score_spread":0.26418849430183944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028818820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985315,0.00024721157,0.0007492228,0.00019491934,0.00014521039,0.00008867068,0.000009170096,0.0000013107226,0.000032772616],"genre_scores_gemma":[0.99881095,0.00008863538,0.00056048133,0.000050629547,0.00043928903,0.000002194943,0.000020141644,0.000006174486,0.000021498128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901384,0.00018098754,0.0004419723,0.00011810211,0.00013701763,0.000108074426],"domain_scores_gemma":[0.998697,0.00004025796,0.0007378971,0.00013359786,0.00035696774,0.000034280867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002951452,0.00011147287,0.00030017103,0.000051405743,0.000071647635,0.0000045714596,0.00016432752,0.000095271804,0.000033340573],"category_scores_gemma":[0.000028959725,0.0000645237,0.0001303787,0.00005779263,0.000052719708,0.000013933692,0.00004212129,0.00014334846,8.6231614e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00057881116,0.00008197294,0.00016089648,0.000008877784,0.00008493202,2.27944e-7,0.00041938917,0.0012878537,0.9968098,0.00007678502,0.00007474357,0.00041570474],"study_design_scores_gemma":[0.0006288772,0.0008189048,0.006823175,0.000028180502,0.0000364356,0.000015726382,0.00026370378,0.00041917976,0.9902702,0.00031588323,0.00030690842,0.00007280181],"about_ca_topic_score_codex":0.00001161004,"about_ca_topic_score_gemma":0.00005163475,"teacher_disagreement_score":0.006662279,"about_ca_system_score_codex":0.000010546688,"about_ca_system_score_gemma":0.00006036207,"threshold_uncertainty_score":0.26312},"labels":[],"label_agreement":null},{"id":"W2029121478","doi":"10.1371/journal.pone.0085193","title":"δ-Opioid Receptor and Somatostatin Receptor-4 Heterodimerization: Possible Implications in Modulation of Pain Associated Signaling","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Somatostatin; Receptor; HEK 293 cells; Opioid; Somatostatin receptor; Signal transduction; μ-opioid receptor; Inhibitory postsynaptic potential; Pharmacology; Opioid receptor; Cell biology; Chemistry; Neuroscience; Medicine; Biology; Internal medicine","score_opus":0.017893121068527574,"score_gpt":0.2149506954045914,"score_spread":0.19705757433606383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029121478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876162,0.000090725734,0.0118480325,0.00011252715,0.000020810776,0.0001929528,0.000020699936,0.000013768097,0.00008429443],"genre_scores_gemma":[0.9896163,0.00008424263,0.009560094,0.000080790116,0.00006276307,0.00002972413,0.00044377774,0.000020245092,0.00010208929],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990008,0.00019727976,0.0002904461,0.00024192595,0.000121654004,0.00014793087],"domain_scores_gemma":[0.99947226,0.00004553097,0.00015867443,0.000162107,0.000113167705,0.00004827158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000541769,0.000103167054,0.00017776953,0.000059502316,0.00005924179,0.00001790573,0.00007480298,0.00012689947,0.00006669653],"category_scores_gemma":[0.00035874915,0.000112425274,0.000029369976,0.00013477229,0.000026096775,0.000007806271,0.000032475964,0.000058271977,0.000002568254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014908806,0.00020197972,0.015292079,0.00003481887,0.000040754003,1.6762124e-8,0.0001065702,0.0001382992,0.982805,0.00018154363,0.000030014004,0.0011540033],"study_design_scores_gemma":[0.00040915108,0.00024872026,0.0037524109,0.00012698032,0.00001408309,1.3311119e-7,0.000040055347,0.0040734275,0.9906737,0.00044219935,0.000071635885,0.00014749773],"about_ca_topic_score_codex":0.000016194028,"about_ca_topic_score_gemma":0.00000957827,"teacher_disagreement_score":0.011539668,"about_ca_system_score_codex":0.000013641393,"about_ca_system_score_gemma":0.000021971973,"threshold_uncertainty_score":0.45845696},"labels":[],"label_agreement":null},{"id":"W2029227703","doi":"10.1016/j.mce.2007.05.006","title":"The growth-promoting effects of angiotensin II in adrenal glomerulosa cells: An interactive tale","year":2007,"lang":"en","type":"review","venue":"Molecular and Cellular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Zona glomerulosa; Angiotensin II; Steroid 11-beta-hydroxylase; Adrenal cortex; Endocrinology; Zona fasciculata; Internal medicine; Angiotensin II receptor type 1; Biology; In vivo; Renin–angiotensin system; Cell biology; Medicine; Steroid","score_opus":0.009813420909936948,"score_gpt":0.2688393590011095,"score_spread":0.2590259380911726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029227703","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0415735,0.95576817,0.0015542562,0.00000898407,0.000391108,0.0005827917,0.000009690252,0.00001086889,0.000100639605],"genre_scores_gemma":[0.05034918,0.948638,0.00041803764,0.000043180404,0.00015285623,0.00005108299,0.00018373826,0.000083938736,0.00007996679],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99731386,0.0004962213,0.0006485518,0.00072123884,0.00016280827,0.0006573487],"domain_scores_gemma":[0.9988572,0.00009824409,0.00035122436,0.00048780628,0.0000921727,0.00011334815],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000306271,0.00048462555,0.00096444093,0.00019413227,0.00015852142,0.000028309374,0.0003925606,0.0004567404,0.00000787544],"category_scores_gemma":[0.00009421135,0.0003777064,0.00040074947,0.00019001386,0.00020075827,0.000006228586,0.00042543752,0.0004656505,0.000002523266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041327585,0.00013192173,0.000002889091,0.0017321052,0.0002855579,0.00041916524,0.000102016,0.0000018628167,0.53786546,0.000528242,0.000018632798,0.4588708],"study_design_scores_gemma":[0.00042916153,0.00076748285,8.7931994e-7,0.0008702439,0.00021937577,0.00017653273,0.000049434027,0.000016555958,0.7968288,0.000119516364,0.20012219,0.0003998001],"about_ca_topic_score_codex":0.000056511777,"about_ca_topic_score_gemma":0.000020234866,"teacher_disagreement_score":0.458471,"about_ca_system_score_codex":0.000025994947,"about_ca_system_score_gemma":0.000089584624,"threshold_uncertainty_score":0.9998675},"labels":[],"label_agreement":null},{"id":"W2029391105","doi":"10.1074/jbc.m005510200","title":"The Glucagon-like Peptide-2 Receptor Mediates Direct Inhibition of Cellular Apoptosis via a cAMP-dependent Protein Kinase-independent Pathway","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"University of Toronto","keywords":"Protein kinase A; ASK1; Cell biology; Apoptosis; Chemistry; Signal transduction; Receptor; Mitogen-activated protein kinase kinase; Kinase; Biology; Biochemistry","score_opus":0.009059550027964691,"score_gpt":0.20668664567506775,"score_spread":0.19762709564710307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029391105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99648225,0.0020486815,0.00042479415,0.00009651635,0.00015248555,0.00016633079,0.000025922722,0.0000084014755,0.00059458916],"genre_scores_gemma":[0.9970078,0.0011167339,0.0004106101,0.00004158376,0.0005513655,0.000019138697,0.000052389572,0.000018959721,0.0007814089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808407,0.0001396474,0.00076262583,0.00030463183,0.00038224747,0.0003267547],"domain_scores_gemma":[0.99874043,0.000049160684,0.0005502098,0.00026722698,0.0002220138,0.0001709436],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000857398,0.00025036454,0.00035929875,0.000019201594,0.00014340597,0.000036752288,0.00035146927,0.00039669307,0.0009282032],"category_scores_gemma":[0.00015805295,0.00015234585,0.00036392207,0.00008907862,0.00013996201,0.000008418433,0.00008210213,0.00031292252,0.000009470882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035410444,0.00015232942,0.00007304624,0.000027723105,0.00008673093,0.000008217967,0.000024676468,0.000031082775,0.9942111,0.0000030409615,0.00020410535,0.004823838],"study_design_scores_gemma":[0.0005150356,0.00053995743,0.000020047104,0.00007541519,0.000019354711,0.000028523924,0.00014367589,0.000008711046,0.9895459,0.000143938,0.008761381,0.00019805292],"about_ca_topic_score_codex":0.0000073215588,"about_ca_topic_score_gemma":0.0000010711242,"teacher_disagreement_score":0.008557275,"about_ca_system_score_codex":0.00004331454,"about_ca_system_score_gemma":0.00009177772,"threshold_uncertainty_score":0.9999851},"labels":[],"label_agreement":null},{"id":"W2029508422","doi":"10.1016/s0014-5793(02)03852-8","title":"Comparison of proto‐oncogenic and mutant forms of the transmembrane region of the Neu receptor in TFE","year":2002,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Transmembrane domain; Chemistry; Transmembrane protein; Mutant; Tyrosine; Mutation; Peptide; Receptor tyrosine kinase; Helix (gastropod); Stereochemistry; Receptor; Biophysics; Biochemistry; Biology; Gene","score_opus":0.017620175238901307,"score_gpt":0.23513055773581146,"score_spread":0.21751038249691015,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029508422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979662,0.0003407765,0.00018952451,0.000977227,0.00007261645,0.00039998515,0.000004834404,0.0000012432598,0.000047636335],"genre_scores_gemma":[0.99957967,0.00006342558,0.00007995393,0.00020939334,0.000021628006,0.000013464291,0.0000016610588,0.000008260829,0.000022560007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993486,0.000055358454,0.00025827976,0.00012566507,0.00010829734,0.00010384029],"domain_scores_gemma":[0.99957955,0.0000082357965,0.00016077505,0.0002182026,0.00001817688,0.000015034234],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009502873,0.00007829997,0.00016164612,0.000018186754,0.000024343855,0.0000026018045,0.00017065002,0.00006900432,0.000018656849],"category_scores_gemma":[0.000014921266,0.00004557159,0.000099239085,0.00008972899,0.000095721305,0.0000026194944,0.000035622725,0.0000734806,1.4860552e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003667928,0.000038173188,0.0042598816,0.000055016288,0.000014286222,1.4590749e-7,0.00037927186,0.00008751044,0.99374634,0.000025152005,0.000155733,0.0012017844],"study_design_scores_gemma":[0.00040240865,0.00010694074,0.0012138521,0.00007210365,0.000010030346,0.0000033388637,0.00009478665,0.00016479268,0.9969732,0.000015250532,0.000887065,0.000056228746],"about_ca_topic_score_codex":0.000018098379,"about_ca_topic_score_gemma":0.000015323873,"teacher_disagreement_score":0.0032268362,"about_ca_system_score_codex":0.0000051480074,"about_ca_system_score_gemma":0.000008164242,"threshold_uncertainty_score":0.18583556},"labels":[],"label_agreement":null},{"id":"W2029649147","doi":"10.1038/npp.2009.117","title":"Ligand functional selectivity advances our understanding of drug mechanisms and drug discovery","year":2009,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; National Institutes of Health; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"Functional selectivity; Agonist; Inverse agonist; Partial agonist; Drug action; Drug discovery; Drug; G protein-coupled receptor; Pharmacology; Receptor; Neuroscience; Biology; Bioinformatics; Genetics","score_opus":0.01382446337881084,"score_gpt":0.2702787971823892,"score_spread":0.25645433380357835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029649147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9667507,0.00088695803,0.030158577,0.0005522783,0.0010291992,0.00016095706,0.0000105185945,0.00001661651,0.00043420854],"genre_scores_gemma":[0.9973276,0.000725701,0.00042654012,0.00082133774,0.00023905793,0.0000061471515,0.000011074301,0.000016153093,0.00042633706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998927,0.00011295727,0.00019668134,0.00041031337,0.00012314711,0.00022989906],"domain_scores_gemma":[0.9996263,0.000021799155,0.00011907311,0.000116796095,0.000041552124,0.00007449118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018777687,0.00016591737,0.00019025289,0.00006553741,0.00011193247,0.000020994927,0.00010260735,0.000071695766,0.000019861518],"category_scores_gemma":[0.000018156989,0.00015919081,0.00007017323,0.00010257787,0.000036153207,0.000020501559,0.000040111263,0.00013704873,0.0000013337916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035379746,0.00007829566,0.00012717686,0.000012044473,0.000026162244,0.000004302818,0.000034147044,0.00016759433,0.9950452,0.0014714955,0.0017291337,0.0009506651],"study_design_scores_gemma":[0.0013487592,0.0004965263,0.00093152723,0.0000088975985,0.00003761918,0.000037225607,0.00022608973,0.00007692439,0.98709786,0.007905656,0.0016211483,0.00021173879],"about_ca_topic_score_codex":0.0000022973436,"about_ca_topic_score_gemma":0.000004814107,"teacher_disagreement_score":0.030576967,"about_ca_system_score_codex":0.000014089661,"about_ca_system_score_gemma":0.000036975813,"threshold_uncertainty_score":0.6491612},"labels":[],"label_agreement":null},{"id":"W2029974064","doi":"10.1242/jcs.03444","title":"Src-dependent phosphorylation of β2-adaptin dissociates the β-arrestin–AP-2 complex","year":2007,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; McGill University; Royal Victoria Hospital","funders":"","keywords":"Internalization; Phosphorylation; Endocytic cycle; Arrestin; Cell biology; Biology; Clathrin; G protein-coupled receptor; Proto-oncogene tyrosine-protein kinase Src; Endocytosis; Receptor; Signal transducing adaptor protein; Tyrosine; Signal transduction; Biochemistry","score_opus":0.014154452415085393,"score_gpt":0.26179341361546116,"score_spread":0.24763896120037576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029974064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98385304,0.00042991806,0.014119512,0.00007428216,0.00025027318,0.00004681936,0.0000010514109,0.000001117901,0.001223977],"genre_scores_gemma":[0.99722075,0.000069845846,0.0023661754,0.0000500409,0.00013952162,1.7343714e-7,6.878854e-7,0.0000041651865,0.00014865867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989803,0.000022664353,0.00031114495,0.00010074574,0.00041215026,0.00017298665],"domain_scores_gemma":[0.99910045,0.00003275408,0.0004302261,0.00011183052,0.00025469626,0.000070062044],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002247297,0.000062952495,0.00009658636,0.00004085496,0.00012967571,0.000027314416,0.00037024028,0.000038282993,0.00005161295],"category_scores_gemma":[0.00012756004,0.000040356004,0.000073593474,0.00015231906,0.00014870934,0.000009293984,0.00005685235,0.000084080864,0.0000012316016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002907815,0.00002948687,0.000649618,0.0000026393684,0.000003884073,0.0000014887229,0.00011096253,0.00023340152,0.99710155,0.00008328273,0.000110045876,0.0016445394],"study_design_scores_gemma":[0.00016540772,0.00019095745,0.005676621,0.000010733631,0.000007893258,0.0000130294675,0.00034723314,0.00014933605,0.99198204,0.00020612808,0.001197792,0.000052827985],"about_ca_topic_score_codex":0.000009475583,"about_ca_topic_score_gemma":0.0000068762706,"teacher_disagreement_score":0.013367683,"about_ca_system_score_codex":0.000019293031,"about_ca_system_score_gemma":0.00011344037,"threshold_uncertainty_score":0.16456701},"labels":[],"label_agreement":null},{"id":"W2030117227","doi":"10.1074/jbc.m110058200","title":"Agonist-induced Internalization of the Platelet-activating Factor Receptor Is Dependent on Arrestins but Independent of G-protein Activation","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Internalization; Arrestin; Cell biology; Agonist; Receptor; G protein-coupled receptor; Biology; Platelet-activating factor; Chemistry; Signal transduction; Biochemistry; Endocrinology","score_opus":0.03898631281976561,"score_gpt":0.24799944594993506,"score_spread":0.20901313313016945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030117227","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99784005,0.00007620028,0.0015376563,0.00007388589,0.00010696384,0.00012273186,0.000018230468,0.0000027635253,0.00022150303],"genre_scores_gemma":[0.99927413,0.000053648517,0.00024914206,0.00005814783,0.00022635014,0.0000037027837,0.000006670574,0.000010492761,0.000117737116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987508,0.000066692744,0.00056463794,0.00018083445,0.00029815536,0.00013885519],"domain_scores_gemma":[0.99848473,0.000030543433,0.0010388113,0.00018430589,0.00020104338,0.0000605518],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018166573,0.0001520087,0.00023691272,0.000021417367,0.00005056599,0.000012881021,0.0003129576,0.00028629694,0.0005566344],"category_scores_gemma":[0.00043045153,0.00009596249,0.00020211044,0.00007488076,0.00004608218,0.0000073344636,0.000080244616,0.0002682141,9.1315536e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015322703,0.000130875,0.00041413467,0.000027994285,0.00005228325,9.233894e-7,0.00004704143,0.000048250353,0.99560314,0.0000075224016,0.00003541311,0.00347922],"study_design_scores_gemma":[0.00042715218,0.00041654205,0.00034127512,0.00017623194,0.0000027287565,0.000012963833,0.00010307819,0.00003966943,0.9978261,0.000050434886,0.00050041045,0.00010338669],"about_ca_topic_score_codex":0.0000058061787,"about_ca_topic_score_gemma":1.8994427e-7,"teacher_disagreement_score":0.0033758332,"about_ca_system_score_codex":0.000041035546,"about_ca_system_score_gemma":0.000032343658,"threshold_uncertainty_score":0.6094756},"labels":[],"label_agreement":null},{"id":"W2030228073","doi":"10.1016/j.bpj.2014.11.2318","title":"Impairment in Acetylcholine Release by Cardiomyocytes Leads to Enhanced Pathological Hypertrophy","year":2015,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Acetylcholine; Vesicular acetylcholine transporter; Internal medicine; Endocrinology; Cholinergic; Muscle hypertrophy; Choline acetyltransferase; Myocyte; Chemistry; Biology; Medicine","score_opus":0.013058434589766233,"score_gpt":0.2542793410062059,"score_spread":0.24122090641643967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030228073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905684,0.0001623386,0.0084668705,0.00034096552,0.00022263937,0.00011085199,0.000010055957,0.000008604122,0.00010924488],"genre_scores_gemma":[0.9965648,0.000070791844,0.0017999292,0.0005367939,0.00083977164,0.000013549773,0.000020462747,0.000018030189,0.00013588773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987705,0.00010743313,0.00025133218,0.00028976475,0.00024686073,0.00033410854],"domain_scores_gemma":[0.9992436,0.0000066546636,0.00005916659,0.0001699969,0.000097797965,0.00042274807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025212346,0.00016909247,0.00022817029,0.000043081523,0.000050845712,0.000048918664,0.00019622591,0.0001252052,0.000022412365],"category_scores_gemma":[0.000097157535,0.00013143539,0.00014508622,0.000120020355,0.000033187003,0.000006132013,0.00010151629,0.00021200154,0.000039688854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002531329,0.00017142072,0.00011953416,0.000001758967,0.00001146195,0.000029582645,0.000046898702,0.00026840498,0.99401546,0.0000149561965,0.0033734636,0.0016939023],"study_design_scores_gemma":[0.0009697793,0.0013938163,0.00013707229,0.000013355586,0.000008203945,0.0000588177,0.00007620452,0.000058560676,0.99046403,0.000051785537,0.0065586925,0.00020969304],"about_ca_topic_score_codex":0.000005868691,"about_ca_topic_score_gemma":6.7554924e-7,"teacher_disagreement_score":0.0066669416,"about_ca_system_score_codex":0.000054230655,"about_ca_system_score_gemma":0.000062342995,"threshold_uncertainty_score":0.53597796},"labels":[],"label_agreement":null},{"id":"W2030240257","doi":"10.1038/sj.jcbfm.9591524.0604","title":"Dopamine D<sub>2/3</sub> receptor binding in aphakia mice measured by microPET","year":2005,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Dopamine; Neuroscience; Dopamine receptor; Receptor; Dopamine receptor D1; Dopamine receptor D2; Medicine; Endocrinology; Internal medicine; Chemistry; Biology","score_opus":0.006050822116153018,"score_gpt":0.20761651885790697,"score_spread":0.20156569674175395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030240257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9854477,0.012403389,0.00074677373,0.00032552602,0.00079277885,0.00014090668,0.000053984593,0.000007847333,0.00008107002],"genre_scores_gemma":[0.98298824,0.0016601229,0.012461931,0.00034326862,0.00223355,0.000005469753,0.00006164185,0.000065306434,0.00018048161],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99765956,0.00020116747,0.00088551256,0.00034312054,0.00042185484,0.0004887604],"domain_scores_gemma":[0.99876255,0.00001768121,0.00050394644,0.0002337312,0.00024450175,0.00023759138],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009917935,0.00032477366,0.0005682981,0.00021367171,0.00008228078,0.00007561936,0.00042435882,0.000267613,0.00013427356],"category_scores_gemma":[0.00014422643,0.0002851202,0.00033105412,0.00024392159,0.000043383454,0.000042310476,0.00008241343,0.00042052136,0.00003268238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015897474,0.00022268068,0.0001623276,0.0000117243135,0.00017992541,0.000009116347,0.000077447265,0.00012964521,0.98307186,0.000012849434,0.0046945354,0.011268916],"study_design_scores_gemma":[0.002694092,0.00017965055,0.000100803285,0.000055958488,0.00012626199,0.0001476128,0.000057024525,0.000044954024,0.9324133,0.000015941689,0.06385504,0.00030941123],"about_ca_topic_score_codex":0.0000070057276,"about_ca_topic_score_gemma":0.000020352052,"teacher_disagreement_score":0.059160497,"about_ca_system_score_codex":0.000027632197,"about_ca_system_score_gemma":0.00011921367,"threshold_uncertainty_score":0.9999601},"labels":[],"label_agreement":null},{"id":"W2030277526","doi":"10.1016/j.abb.2011.05.008","title":"Intracellular regulation of heterotrimeric G-protein signaling modulates vascular smooth muscle cell contraction","year":2011,"lang":"en","type":"review","venue":"Archives of Biochemistry and Biophysics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Heterotrimeric G protein; Cell biology; Vascular smooth muscle; Intracellular; Extracellular; Biology; Receptor; Signal transduction; Contractility; Myocyte; G protein-coupled receptor; G protein; Endocrinology; Biochemistry; Smooth muscle","score_opus":0.012963676855872991,"score_gpt":0.224800951294463,"score_spread":0.21183727443859002,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030277526","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.12617466,0.87018114,0.0029823342,7.826993e-7,0.00005290989,0.0003698105,0.000064354834,0.000008596222,0.00016538773],"genre_scores_gemma":[0.2551502,0.7418096,0.002231405,0.0000019627798,0.000181168,0.000020245467,0.00047764572,0.00004310389,0.00008466865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850285,0.0000856695,0.0005806,0.00050134223,0.00012106642,0.00020848397],"domain_scores_gemma":[0.99866027,0.000029934334,0.0007511709,0.00042991797,0.000049828046,0.00007888787],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011568704,0.00037731134,0.00079629495,0.000057652927,0.000058618683,0.0000128440515,0.00022157578,0.00033947348,0.000015944966],"category_scores_gemma":[0.000017495273,0.00034443382,0.00052002893,0.00010241954,0.00019289613,0.0000066271864,0.00011455466,0.00017321383,8.1140087e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001856722,0.000080047575,4.0150124e-7,0.0050644614,0.000102437145,3.6273488e-7,0.000021833468,0.0000068399154,0.7759675,0.000025991265,0.00000137474,0.2187102],"study_design_scores_gemma":[0.00020561843,0.00017666821,0.000002491311,0.0018690665,0.00028728522,0.0000016458812,0.00002088788,0.000045655597,0.97357804,0.00033643525,0.023139326,0.00033686747],"about_ca_topic_score_codex":0.0000225522,"about_ca_topic_score_gemma":1.154606e-7,"teacher_disagreement_score":0.21837333,"about_ca_system_score_codex":0.0000053416197,"about_ca_system_score_gemma":0.0000846028,"threshold_uncertainty_score":0.99990076},"labels":[],"label_agreement":null},{"id":"W2030600537","doi":"10.1124/jpet.107.131524","title":"A Conservative, Single-Amino Acid Substitution in the Second Cytoplasmic Domain of the Human Serotonin2C Receptor Alters Both Ligand-Dependent and -Independent Receptor Signaling","year":2007,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of General Medical Sciences","keywords":"Receptor; Chemistry; Ligand (biochemistry); Cytoplasm; Serotonin; Substitution (logic); Domain (mathematical analysis); Biophysics; Cell biology; Stereochemistry; Pharmacology; Biochemistry; Biology; Computer science; Mathematics","score_opus":0.02269233207162927,"score_gpt":0.3006041209160847,"score_spread":0.2779117888444554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030600537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99599296,0.0026853704,0.0003738606,0.00017321961,0.0004593257,0.0002536273,0.0000070754245,0.0000017159865,0.00005285465],"genre_scores_gemma":[0.9979739,0.00013548307,0.0004516216,0.0012102245,0.00016584178,0.000005514304,0.0000028322142,0.000012067759,0.00004246898],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987484,0.00023353953,0.00045874214,0.00016461102,0.00018541301,0.00020926051],"domain_scores_gemma":[0.99938834,0.000045856235,0.00038278266,0.00008082472,0.00005424531,0.000047927235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010455486,0.00016288379,0.00021072451,0.000062431216,0.00017040086,0.00002225346,0.00021013877,0.00014747377,0.000080875405],"category_scores_gemma":[0.000003790979,0.00010714631,0.000083824205,0.00007481188,0.00022675385,0.000016886439,0.000064562606,0.0002713526,2.8632587e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004936553,0.00018981165,0.0018920415,0.000013441763,0.00013254509,0.000005754235,0.0019346516,0.000014026137,0.9950264,0.00010563526,0.00006354123,0.00012848196],"study_design_scores_gemma":[0.0019302039,0.00081034563,0.000371714,0.00002601443,0.000035142803,0.00012477099,0.0038002243,0.000006191595,0.9902515,0.00007217039,0.0024551935,0.00011656381],"about_ca_topic_score_codex":0.0000029567955,"about_ca_topic_score_gemma":0.000008352158,"teacher_disagreement_score":0.0047749495,"about_ca_system_score_codex":0.000050387545,"about_ca_system_score_gemma":0.00005229023,"threshold_uncertainty_score":0.43692997},"labels":[],"label_agreement":null},{"id":"W2030906695","doi":"10.1016/j.bpj.2009.12.2845","title":"TARP Modulation of AMPA Receptor Pharmacology: Polyamine Block and Competitive Antagonism","year":2010,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"CNQX; AMPA receptor; Chemistry; Antagonist; Competitive antagonist; Population; Biophysics; Receptor; Pharmacology; Biochemistry; Biology; Glutamate receptor; Medicine","score_opus":0.006621243287114993,"score_gpt":0.24916385418363027,"score_spread":0.24254261089651527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030906695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99825704,0.000032591182,0.00073196914,0.00015859191,0.0006503694,0.00006347412,0.000019311614,0.0000038954036,0.00008273274],"genre_scores_gemma":[0.9963843,0.00009287167,0.0019368419,0.00008356821,0.0014097645,0.0000017599166,0.000018500525,0.000011900293,0.000060460618],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993706,0.00003913898,0.00018001992,0.00015473139,0.00010877344,0.00014674992],"domain_scores_gemma":[0.9995685,0.000011445965,0.00012785586,0.00007456371,0.000103899765,0.0001137171],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001138778,0.00010510158,0.00014341825,0.000031552107,0.00008366661,0.000019139554,0.00009086333,0.00010724265,0.000111912384],"category_scores_gemma":[0.000016751745,0.00008928912,0.000075067364,0.000041509567,0.000105190724,0.0000058157198,0.000048578688,0.00021858246,0.0000035244577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006821605,0.0000751549,0.0001331521,0.000004473508,0.000040423813,0.0000019443753,0.000026595293,0.000010130174,0.99781215,0.00054432475,0.00019373653,0.0010897225],"study_design_scores_gemma":[0.0005182838,0.00031457297,0.0010161984,0.000005636159,0.000018399067,0.000060097333,0.00003701931,0.00028538913,0.99365044,0.00008978401,0.0038981165,0.0001060748],"about_ca_topic_score_codex":0.000003953636,"about_ca_topic_score_gemma":8.605758e-7,"teacher_disagreement_score":0.0041616973,"about_ca_system_score_codex":0.0000041126905,"about_ca_system_score_gemma":0.000030127934,"threshold_uncertainty_score":0.36411044},"labels":[],"label_agreement":null},{"id":"W2031069848","doi":"10.1074/jbc.m113.455337","title":"Defining the Molecular Basis for the First Potent and Selective Orthosteric Agonists of the FFA2 Free Fatty Acid Receptor","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Wellcome Trust; Canadian Institutes of Health Research; Strategiske Forskningsråd","keywords":"Allosteric regulation; G protein-coupled receptor; Ligand (biochemistry); Receptor; Function (biology); Functional selectivity; Chemistry; Biology; Biochemistry; Cell biology","score_opus":0.00935298941352982,"score_gpt":0.21707638783873326,"score_spread":0.20772339842520343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031069848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896848,0.0050719855,0.00302117,0.0017370537,0.00012299324,0.0002208618,0.000022191918,0.0000023904272,0.00011655012],"genre_scores_gemma":[0.997672,0.00036697395,0.0013531958,0.00038283676,0.00015896767,0.000025778321,0.000003878644,0.000009867572,0.000026464582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912,0.00005089119,0.00033498398,0.00016927022,0.00013767781,0.00018716339],"domain_scores_gemma":[0.99893326,0.00012108731,0.0003906948,0.00026789572,0.00023254253,0.000054537533],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037749324,0.0001474254,0.00019741252,0.0000061032165,0.00019926263,0.00003688163,0.00052739406,0.0001872767,0.00006222479],"category_scores_gemma":[0.0006037218,0.00006074056,0.00026721135,0.00007247108,0.00017890488,0.000004314399,0.0002173084,0.00020876901,5.087648e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006914492,0.000024870475,0.0010134389,0.00001763811,0.00010456136,4.2800448e-7,0.00003618321,0.000025377441,0.99625564,0.00003428659,0.0007060405,0.0017124184],"study_design_scores_gemma":[0.00028869897,0.00024438626,0.002496457,0.00003236279,0.000036610123,0.0000575573,0.00026217653,0.000029426716,0.99287635,0.00030679768,0.0032764608,0.00009271189],"about_ca_topic_score_codex":0.000005171332,"about_ca_topic_score_gemma":8.433741e-7,"teacher_disagreement_score":0.007987234,"about_ca_system_score_codex":0.000015486621,"about_ca_system_score_gemma":0.00004824647,"threshold_uncertainty_score":0.24769281},"labels":[],"label_agreement":null},{"id":"W2031075865","doi":"10.1016/j.cellsig.2012.06.011","title":"D2-like dopamine and β-adrenergic receptors form a signaling complex that integrates Gs- and Gi-mediated regulation of adenylyl cyclase","year":2012,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Deafness and Other Communication Disorders; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Heterotrimeric G protein; Adenylyl cyclase; Gs alpha subunit; Receptor; G protein; Cell biology; Signal transduction; G protein-coupled receptor; G beta-gamma complex; Chemistry; cAMP-dependent pathway; Gq alpha subunit; G alpha subunit; Dopamine receptor; Dopamine receptor D2; Biology; Biochemistry; Protein subunit","score_opus":0.01919955797622462,"score_gpt":0.2197272635927378,"score_spread":0.20052770561651317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031075865","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9647382,0.0061360947,0.028587457,0.000018064258,0.00020801838,0.00019761549,0.000009871479,0.000021422306,0.00008329413],"genre_scores_gemma":[0.9943007,0.00041684057,0.0043313336,0.00005179303,0.0002765776,0.0000120255645,0.00041763912,0.00004577014,0.00014730351],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853843,0.000087704655,0.00041484536,0.0003688646,0.00020315571,0.00038699975],"domain_scores_gemma":[0.99919856,0.000062752595,0.00025302946,0.00018581406,0.00009796553,0.00020189394],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057851116,0.00027859805,0.00031675416,0.00010714081,0.00014442278,0.000044166285,0.00011808992,0.00023311606,0.00018071882],"category_scores_gemma":[0.000053029642,0.00025565334,0.00009353696,0.000120741934,0.00009467755,0.000026872904,0.000100408986,0.00013207244,0.0000025484173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006417204,0.00004104901,0.0026983425,0.00006590927,0.00006058725,0.0000011276459,0.000273107,0.00016857286,0.9951893,0.00015936107,0.000036951995,0.0012414831],"study_design_scores_gemma":[0.0005476252,0.00017564779,0.0002904988,0.00008672687,0.00005815384,0.000012554537,0.00052457734,0.0031255907,0.99292034,0.00014554041,0.001803956,0.00030877968],"about_ca_topic_score_codex":0.000031211664,"about_ca_topic_score_gemma":0.000005606945,"teacher_disagreement_score":0.029562555,"about_ca_system_score_codex":0.000015539174,"about_ca_system_score_gemma":0.000024578349,"threshold_uncertainty_score":0.99998957},"labels":[],"label_agreement":null},{"id":"W2031224562","doi":"10.1016/s1046-2023(02)00092-0","title":"Photobleaching fluorescence resonance energy transfer reveals ligand-induced oligomer formation of human somatostatin receptor subtypes","year":2002,"lang":"en","type":"article","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute for Health and Care Research","keywords":"Photobleaching; Förster resonance energy transfer; Fluorescence recovery after photobleaching; G protein-coupled receptor; Biophysics; Receptor; Chemistry; Fluorescence-lifetime imaging microscopy; Fluorescence microscope; Ligand (biochemistry); Somatostatin receptor; Cell biology; Fluorescence; Biology; Biochemistry; Membrane","score_opus":0.03283487197374614,"score_gpt":0.30686071162480316,"score_spread":0.27402583965105703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031224562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84851307,0.0012575672,0.14923501,0.00003222879,0.00013593571,0.00010760609,0.000008850141,0.000017408443,0.0006923369],"genre_scores_gemma":[0.9143869,0.00034401906,0.0845403,0.00010414187,0.00010542853,0.000023298899,0.000029980925,0.000027559943,0.0004383585],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986091,0.00036043813,0.00038129784,0.00027465756,0.00014245372,0.0002320559],"domain_scores_gemma":[0.99946934,0.000033740336,0.000092646136,0.00026710084,0.00007578391,0.00006137043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070994097,0.00015951546,0.00023306481,0.000056915927,0.00011780331,0.000018984307,0.00018004997,0.0001599676,0.00016505794],"category_scores_gemma":[0.00008159899,0.00014959644,0.00010995382,0.000117444324,0.000027669987,0.000013206833,0.000031420623,0.00008998691,0.0000034581888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018487237,0.000031240557,0.000035042893,0.000030469475,0.0000113010365,3.9755923e-7,0.00037522407,0.0000043577606,0.96316636,0.0005600702,0.00029745174,0.03546958],"study_design_scores_gemma":[0.00028076288,0.00020567507,0.000031978474,0.00005727659,0.000010668438,0.000003842331,0.000076955635,0.00048771696,0.9924173,0.00022992896,0.006020591,0.00017731813],"about_ca_topic_score_codex":0.000043985103,"about_ca_topic_score_gemma":0.0000065925033,"teacher_disagreement_score":0.06587386,"about_ca_system_score_codex":0.00001167155,"about_ca_system_score_gemma":0.000009044433,"threshold_uncertainty_score":0.61003655},"labels":[],"label_agreement":null},{"id":"W2031498189","doi":"10.1016/j.bmcl.2010.11.084","title":"Azaindoles as potent CRTH2 receptor antagonists","year":2010,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Pharmacology; Stereochemistry; Pharmacokinetics; Antagonist; Structural isomer; Chemical synthesis; Structure–activity relationship; Receptor; Combinatorial chemistry; In vitro; Biochemistry","score_opus":0.003594928298812503,"score_gpt":0.21358436707803544,"score_spread":0.20998943877922294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031498189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99341476,0.0002758629,0.0006251774,0.003809026,0.000889971,0.00013869551,0.000016583674,0.000049373248,0.00078053266],"genre_scores_gemma":[0.99295855,0.00009013909,0.0009898635,0.0025638628,0.0025300349,0.000014670502,0.00023567503,0.00005934303,0.0005578576],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998156,0.000028284057,0.00032877823,0.0006214141,0.00037763687,0.00048789062],"domain_scores_gemma":[0.9989113,0.000014248121,0.00014326072,0.00054491276,0.00007656259,0.0003097236],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029617152,0.00033141323,0.0002445215,0.000026301574,0.00016445735,0.00004719932,0.00045569267,0.00031795053,0.0020531127],"category_scores_gemma":[0.0001868482,0.0003043464,0.00015128142,0.000109775225,0.00019855796,0.000005739953,0.00012133545,0.00044281606,0.000115319635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006526172,0.00004526117,0.0002494186,0.000037831313,0.000051649047,0.000022789829,0.000044232253,8.479905e-7,0.9898168,0.000017818531,0.008309819,0.00133831],"study_design_scores_gemma":[0.0005885806,0.000063872416,0.000115181276,0.000028221499,0.00002748284,0.0001867964,0.00014829681,0.0000046425926,0.9366311,0.000020189951,0.061841264,0.00034437442],"about_ca_topic_score_codex":0.000029150868,"about_ca_topic_score_gemma":0.0000037146317,"teacher_disagreement_score":0.053531446,"about_ca_system_score_codex":0.00002789045,"about_ca_system_score_gemma":0.00013759416,"threshold_uncertainty_score":0.9999409},"labels":[],"label_agreement":null},{"id":"W2031775832","doi":"10.1007/s12035-015-9152-z","title":"Revisiting the Serotonin Hypothesis: Implications for Major Depressive Disorders","year":2015,"lang":"en","type":"review","venue":"Molecular Neurobiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":245,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Serotonergic; Antidepressant; Major depressive disorder; Serotonin; Serotonin transporter; Animal models of depression; Psychology; Neuroscience; Neurotransmitter; Mood disorders; 5-HT receptor; Neurotransmission; Serotonin Plasma Membrane Transport Proteins; Medicine; Mood; Receptor; Psychiatry; Internal medicine; Central nervous system; Hippocampus; Anxiety","score_opus":0.039422774160968496,"score_gpt":0.31314866235558786,"score_spread":0.27372588819461935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031775832","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010398283,0.9868732,0.009740306,0.00036266743,0.00026694185,0.002159672,0.00020912912,0.00002694567,0.0002571726],"genre_scores_gemma":[0.00014956598,0.994391,0.0011863181,0.00046616598,0.0005487512,0.001978511,0.0008752564,0.0001647322,0.00023966911],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975711,0.0005158341,0.0005184735,0.00084770244,0.00006389206,0.00048298718],"domain_scores_gemma":[0.9982918,0.00014249561,0.00043618484,0.000902959,0.00012741986,0.0000991789],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038124807,0.0004886438,0.0008620198,0.00006800987,0.00022544446,0.0000475074,0.0007997787,0.0005372073,0.000012578125],"category_scores_gemma":[0.00033315786,0.00034307523,0.00072907005,0.00014094623,0.00010622952,0.0000022542015,0.00027162826,0.00025651735,0.000016483335],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018856115,0.000023596896,0.0000037904442,0.0012308167,0.00040652734,0.0000021606534,0.000009317361,0.00003093741,0.028567001,0.0011010754,0.0019083201,0.9666976],"study_design_scores_gemma":[0.00022713248,0.00013735423,0.0000016261423,0.00026080135,0.00047577443,0.00005935436,0.0000060643288,0.000002171253,0.0017922147,0.00069138734,0.99596876,0.00037733308],"about_ca_topic_score_codex":0.0000037507689,"about_ca_topic_score_gemma":0.0000026108464,"teacher_disagreement_score":0.99406046,"about_ca_system_score_codex":0.000022647866,"about_ca_system_score_gemma":0.00023034531,"threshold_uncertainty_score":0.9999021},"labels":[],"label_agreement":null},{"id":"W2031818051","doi":"10.1073/pnas.1320239111","title":"G-protein–coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion","year":2014,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Cancer Institute","keywords":"Biology; Cancer research; G protein-coupled receptor; Breast cancer; Cell growth; Triple-negative breast cancer; Cancer; Regulator; Receptor; Signal transduction; Gene; Cell biology; Genetics","score_opus":0.015544692053544612,"score_gpt":0.25470073943153226,"score_spread":0.23915604737798765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031818051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99831504,0.000097540644,0.00000445727,0.0012702057,0.0000054788165,0.00017066451,0.000014675982,9.360513e-7,0.00012098832],"genre_scores_gemma":[0.9985569,0.00009072105,0.001044332,0.000190221,0.00003987397,0.000012119932,2.3781806e-7,0.0000028483087,0.000062731175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924725,0.0000053930557,0.00018100085,0.00019314112,0.00030098663,0.00007222505],"domain_scores_gemma":[0.9996077,0.000007928465,0.0002169417,0.00000703937,0.00014129674,0.000019138126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005615678,0.000062145795,0.00009547714,0.000053482527,0.000050769097,0.00001252737,0.00014625685,0.00008414947,0.000018775378],"category_scores_gemma":[0.000056473593,0.000042673582,0.000021457416,0.0001281846,0.00017014834,0.00002465959,0.00007924924,0.000050487037,5.900239e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025189123,0.00001766933,0.0055806134,0.00008257593,0.0000031918244,1.9217569e-10,0.0001671333,0.0000036169406,0.9933821,0.00044547569,0.000082486506,0.00020995401],"study_design_scores_gemma":[0.0002347888,0.00006337646,0.0069393367,0.00011014452,0.0000030430617,9.582951e-7,0.00004614686,0.0017783653,0.98808545,0.0026411978,0.000047266047,0.000049917347],"about_ca_topic_score_codex":0.0000146804105,"about_ca_topic_score_gemma":1.3725955e-7,"teacher_disagreement_score":0.0052966345,"about_ca_system_score_codex":0.000004819168,"about_ca_system_score_gemma":0.000019618048,"threshold_uncertainty_score":0.17401783},"labels":[],"label_agreement":null},{"id":"W2032099552","doi":"10.1097/00001756-200105250-00036","title":"Autoreceptor preference of dopamine D2 receptor agonists correlates with preferential coupling to cyclic AMP","year":2001,"lang":"en","type":"article","venue":"Neuroreport","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Wilfrid Laurier University; Université Laval; Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Autoreceptor; Dopamine; Second messenger system; Dopamine receptor D2; Postsynaptic potential; Chemistry; Receptor; Dopamine receptor; Endocrinology; Biology; Internal medicine; Agonist; Neuroscience; Biochemistry","score_opus":0.02357570393316208,"score_gpt":0.24750079528211272,"score_spread":0.22392509134895064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032099552","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870616,0.0000770354,0.011191689,0.000040164454,0.0005099707,0.00032840774,0.000010760178,0.000041879746,0.0007384607],"genre_scores_gemma":[0.9948235,0.000103211925,0.0019469574,0.000080468635,0.00025208836,0.000042223557,0.00018034651,0.000053823052,0.0025173372],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830467,0.000024775209,0.00045259882,0.00058346806,0.00030368727,0.00033081137],"domain_scores_gemma":[0.998866,0.000014060356,0.00026188776,0.00048891344,0.00018777249,0.00018135352],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015901512,0.00025263047,0.00028303196,0.00006670607,0.000082127095,0.000033311655,0.00023620606,0.00014765811,0.00042369438],"category_scores_gemma":[0.000100380545,0.00021436298,0.00009095436,0.00017867757,0.000057995137,0.000008338668,0.00011738151,0.00013872568,0.000028307506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032840762,0.00009513799,0.015820183,0.000017583247,0.00004722041,0.000007851425,0.000043784814,0.0012259504,0.9801787,0.00002631614,0.0005596546,0.0016492014],"study_design_scores_gemma":[0.00047459977,0.0010407916,0.0025958065,0.00005687853,0.00003479414,0.0001050913,0.00002726357,0.00011901262,0.9276979,0.000014526169,0.067494184,0.0003391538],"about_ca_topic_score_codex":0.000031366966,"about_ca_topic_score_gemma":0.000031348183,"teacher_disagreement_score":0.06693453,"about_ca_system_score_codex":0.000013603015,"about_ca_system_score_gemma":0.0001092618,"threshold_uncertainty_score":0.8741469},"labels":[],"label_agreement":null},{"id":"W2032396664","doi":"10.1016/j.ejphar.2007.11.060","title":"Mu-opioid receptor heterooligomer formation with the dopamine D1 receptor as directly visualized in living cells","year":2008,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Canada Research Chairs; University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Dopamine receptor D1; Opioid receptor; Dopamine; Receptor; Dopamine receptor; Chemistry; Cell biology; Dopamine receptor D2; Dopamine receptor D3; 5-HT5A receptor; Opioid; Biophysics; Biology; Biochemistry; Endocrinology","score_opus":0.011553798345119558,"score_gpt":0.2604855309966109,"score_spread":0.24893173265149138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032396664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948019,0.000715314,0.0025305697,0.0003300605,0.0007634605,0.00016298135,0.0000033737879,0.000007573651,0.00068480684],"genre_scores_gemma":[0.9949902,0.0014130459,0.0011933211,0.0009022402,0.0008815604,0.000004378176,0.00000822673,0.000044403125,0.00056259934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99789256,0.0009502053,0.0004934577,0.00018730234,0.0001897874,0.00028665917],"domain_scores_gemma":[0.9991166,0.00005918184,0.0004524792,0.00011280414,0.00016083261,0.000098083015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010552931,0.00018930472,0.00024357728,0.00011461371,0.00013176475,0.000020356905,0.0003323852,0.000048311464,0.00080871437],"category_scores_gemma":[0.00004223594,0.00012685356,0.00011411207,0.00013930861,0.00009077629,0.000023788802,0.000083913335,0.00028822685,0.000069466536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044441162,0.000086466614,0.000072442956,0.0000097993425,0.00006742887,0.00007359522,0.0005851875,0.00020541176,0.9843753,0.0000026480423,0.012878878,0.0011984237],"study_design_scores_gemma":[0.0013643664,0.0012347357,0.0001366261,0.00003972169,0.000026186592,0.00031445725,0.00016303334,0.00003649537,0.86569804,9.1405485e-7,0.13082907,0.00015639103],"about_ca_topic_score_codex":0.0000034237582,"about_ca_topic_score_gemma":0.0000023550783,"teacher_disagreement_score":0.118677296,"about_ca_system_score_codex":0.000032135576,"about_ca_system_score_gemma":0.00006913955,"threshold_uncertainty_score":0.88548553},"labels":[],"label_agreement":null},{"id":"W2033009192","doi":"10.1038/sj.bjp.0704049","title":"Agonist and antagonist activities on human NPFF<sub>2</sub> receptors of the NPY ligands GR231118 and BIBP3226","year":2001,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale","keywords":"Neuropeptide Y receptor; Receptor; Agonist; Antagonist; Chemistry; Nociceptin receptor; Internal medicine; Endocrinology; Endogenous agonist; Neuropeptide; Opioid peptide; Opioid; Biology; Biochemistry; Medicine","score_opus":0.011218026768926111,"score_gpt":0.26652109900660415,"score_spread":0.255303072237678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033009192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99638796,0.0022266863,0.00005158069,0.00024156488,0.00083896273,0.00009558736,0.000010803898,0.000003084056,0.00014374814],"genre_scores_gemma":[0.9904221,0.008530171,0.000042399708,0.00035620347,0.0005186226,0.0000029135772,0.000004316579,0.000020125606,0.00010310426],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990153,0.00011350605,0.00034086703,0.00018361797,0.0001397256,0.00020702134],"domain_scores_gemma":[0.99940187,0.00002906506,0.00032655915,0.000062990366,0.000090667774,0.00008886324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033878573,0.0001355094,0.00025898308,0.00006526276,0.00025116213,0.00004854953,0.00017027352,0.00013310298,0.0000573298],"category_scores_gemma":[0.0000271831,0.00012421075,0.00010957254,0.00008704347,0.00027281692,0.00001161907,0.00009366163,0.00024564395,2.9083643e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015737566,0.00008316095,0.0007856161,0.00001772974,0.00009787546,0.00004950707,0.000043734657,0.000009496674,0.98244494,0.00003434394,0.00448505,0.0117911445],"study_design_scores_gemma":[0.0011877505,0.00076071743,0.0012368702,0.000060552593,0.00006409689,0.001958458,0.00012722227,0.000004873536,0.9869042,0.00012041528,0.00744595,0.00012889711],"about_ca_topic_score_codex":0.000016424712,"about_ca_topic_score_gemma":0.000025461974,"teacher_disagreement_score":0.011662248,"about_ca_system_score_codex":0.000013664116,"about_ca_system_score_gemma":0.000057177003,"threshold_uncertainty_score":0.50651675},"labels":[],"label_agreement":null},{"id":"W2033244960","doi":"10.1038/sj.embor.7400373","title":"Monitoring agonist‐promoted conformational changes of β‐arrestin in living cells by intramolecular BRET","year":2005,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":171,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Javna Agencija za Raziskovalno Dejavnost RS; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"Förster resonance energy transfer; Agonist; G protein-coupled receptor; Biophysics; Receptor; Intramolecular force; Conformational change; Chemistry; BETA (programming language); Biochemistry; Stereochemistry; Cell biology; Fluorescence; Biology","score_opus":0.005979926616310477,"score_gpt":0.2251462197229468,"score_spread":0.21916629310663632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033244960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99620765,0.0007877889,0.0019239549,0.000055732005,0.00024984073,0.00012924682,0.0000056690074,0.000010316941,0.0006297713],"genre_scores_gemma":[0.99739987,0.00008251634,0.0019885541,0.00004068755,0.00021194982,0.000012807972,0.000049645194,0.000015999323,0.00019794924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900955,0.000032142147,0.00036210273,0.00022377452,0.00017557686,0.00019686292],"domain_scores_gemma":[0.99945104,0.000010353073,0.00021558133,0.0002039304,0.00006263549,0.000056433044],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000352345,0.00012098554,0.00014976299,0.00004604613,0.000035708574,0.00001964761,0.00007583129,0.00012297601,0.00008801157],"category_scores_gemma":[0.000072540584,0.00012659401,0.000047883925,0.0000686421,0.000025056086,0.0000064187607,0.000055448505,0.00008037919,0.0000018394247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000054710254,0.00004015823,0.0011235162,0.000017612256,0.0000134514585,0.000016491003,0.00014165169,0.00032202655,0.99480814,0.000011020085,0.00033891236,0.003161574],"study_design_scores_gemma":[0.000090434056,0.00006582725,0.00037357234,0.00007919428,0.000005077081,0.000046521178,0.00006472528,0.00017314858,0.99254304,0.000029684961,0.006393424,0.000135354],"about_ca_topic_score_codex":0.000035406374,"about_ca_topic_score_gemma":0.000010878177,"teacher_disagreement_score":0.0060545113,"about_ca_system_score_codex":0.000017683573,"about_ca_system_score_gemma":0.000049649425,"threshold_uncertainty_score":0.51623535},"labels":[],"label_agreement":null},{"id":"W2033577990","doi":"10.1016/j.cellsig.2010.03.015","title":"RGS2 inhibits β-adrenergic receptor-induced cardiomyocyte hypertrophy","year":2010,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba; Western University","funders":"Canadian Institutes of Health Research","keywords":"RGS2; Internal medicine; Endocrinology; Adenylyl cyclase; Downregulation and upregulation; G protein; Receptor; Forskolin; Gs alpha subunit; Biology; Muscle hypertrophy; Wortmannin; Agonist; Signal transduction; Atrial natriuretic peptide; Protein kinase B; Cell biology; Stimulation; Medicine; GTPase-activating protein","score_opus":0.009117117156187649,"score_gpt":0.20794053778067959,"score_spread":0.19882342062449193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033577990","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98113245,0.0007333918,0.014908849,0.000031911728,0.0012851864,0.00018345907,0.0000060418843,0.00005185471,0.0016668716],"genre_scores_gemma":[0.9930315,0.000068597765,0.0041565564,0.00014916541,0.0017032063,0.0000249095,0.00016389064,0.000080715276,0.00062145235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819374,0.000073506715,0.00033713615,0.0006389259,0.00027590344,0.00048081652],"domain_scores_gemma":[0.9990224,0.000015186981,0.00012035436,0.0004785459,0.0001452426,0.0002182699],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004037095,0.00031449416,0.00027938976,0.00008445575,0.00022621587,0.00008614659,0.0003433126,0.00038901423,0.0004668889],"category_scores_gemma":[0.00005750983,0.00030953198,0.00027852648,0.00015621264,0.00004784706,0.000008631979,0.00012782523,0.0003876021,0.00010390158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034361266,0.000030650117,0.000051741175,0.000012050793,0.00005800676,0.000009178654,0.000037517224,0.000269138,0.9968523,0.0004378339,0.00014654952,0.0020606986],"study_design_scores_gemma":[0.0004104986,0.00016042124,0.000005165495,0.00001732068,0.00002650003,0.00001316057,0.00003812512,0.0003783991,0.9680387,0.00013030546,0.030373864,0.00040755016],"about_ca_topic_score_codex":0.000022782438,"about_ca_topic_score_gemma":0.0000075073267,"teacher_disagreement_score":0.030227315,"about_ca_system_score_codex":0.000012811838,"about_ca_system_score_gemma":0.00009134137,"threshold_uncertainty_score":0.9999357},"labels":[],"label_agreement":null},{"id":"W2033645186","doi":"10.1016/s0091-3057(00)00175-1","title":"Oral Administration of Adrafinil Improves Discrimination Learning in Aged Beagle Dogs","year":2000,"lang":"en","type":"article","venue":"Pharmacology Biochemistry and Behavior","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; The Scarborough Hospital","funders":"","keywords":"Beagle; Vigilance (psychology); Placebo; Facilitation; Audiology; Agonist; Psychology; Medicine; Anesthesia; Internal medicine; Neuroscience","score_opus":0.011931602932243844,"score_gpt":0.29479190639031067,"score_spread":0.28286030345806684,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033645186","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99922013,0.00029321844,0.000019035346,0.000050444116,0.00007593878,0.0001342433,0.000008964698,0.000009785633,0.0001882112],"genre_scores_gemma":[0.9980903,0.0002229111,0.00021914385,0.000046620225,0.00009293758,0.000057662044,0.00020787248,0.000010962929,0.0010515751],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991859,0.000054112432,0.00023675589,0.0002845096,0.000068236055,0.00017045486],"domain_scores_gemma":[0.9997515,0.000008214309,0.000077696015,0.00007566284,0.000029878236,0.000057013578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016900581,0.00012922047,0.0001413018,0.000026074777,0.000060779177,0.000010390439,0.0000837864,0.00018236417,0.00048104816],"category_scores_gemma":[0.00001317184,0.00013246525,0.000046755413,0.000058700545,0.00008809821,0.0000075924972,0.00002856466,0.00014325808,0.000001329309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020243213,0.00021757146,0.0030459433,0.0000372766,0.0000107544865,0.0000074411923,0.000052721134,0.000011302501,0.9814412,0.000001770021,0.00006383175,0.014907729],"study_design_scores_gemma":[0.0008176408,0.00030030095,0.0053379284,0.000010060924,0.00007224662,0.000021014721,0.0000748624,0.000062859785,0.9927278,0.0000075512266,0.00042482273,0.00014292348],"about_ca_topic_score_codex":0.000015488267,"about_ca_topic_score_gemma":0.000008642954,"teacher_disagreement_score":0.014764805,"about_ca_system_score_codex":0.0000092757455,"about_ca_system_score_gemma":0.000049401635,"threshold_uncertainty_score":0.5401776},"labels":[],"label_agreement":null},{"id":"W2033751405","doi":"10.1016/j.jcjd.2014.07.034","title":"Acetylcholine Muscarinic Type 1 Receptor (M1R) Antagonists Modulate Nerve Growth Through a Ca2+/Calmodulin-Dependent Kinase Kinase 2 (CaMKK2) Pathway in Adult Sensory Neurons","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Manitoba Beekeepers' Association","funders":"","keywords":"AMPK; AMP-activated protein kinase; Protein kinase A; Endocrinology; Internal medicine; Mitochondrial biogenesis; Muscarinic acetylcholine receptor; Medicine; Kinase; Cell biology; Receptor; Biology; Mitochondrion","score_opus":0.010772588381605875,"score_gpt":0.21787809347530826,"score_spread":0.20710550509370237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033751405","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969566,0.0009394991,0.000142251,0.00044810207,0.0011043267,0.0001437833,0.00006731222,0.0000054186758,0.00019270748],"genre_scores_gemma":[0.99730873,0.00010713871,0.00086149777,0.00073313946,0.0006851022,0.0000047998797,0.00006219597,0.00006105687,0.0001763407],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978849,0.00024876115,0.00060253154,0.00038917334,0.00020687569,0.0006677475],"domain_scores_gemma":[0.99823445,0.00003574051,0.00029820384,0.0003569128,0.00044269292,0.00063200714],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047107114,0.0003043366,0.00041405222,0.00018576333,0.00013215032,0.0000800339,0.0003924321,0.00025984188,0.00011830833],"category_scores_gemma":[0.0005721919,0.00029116814,0.0002098019,0.00019358621,0.00009444529,0.000026875849,0.000046644855,0.00040778398,0.000016998112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002838582,0.000053575826,0.008281219,0.0000420247,0.0000678763,0.000051582785,0.0001897758,0.00082636706,0.9878562,0.00022136931,0.00066322234,0.0017183659],"study_design_scores_gemma":[0.0017958458,0.0011519621,0.002502434,0.00017936253,0.00004073524,0.000026789341,0.00016210781,0.0004946386,0.9849416,0.00048227582,0.007640024,0.000582214],"about_ca_topic_score_codex":0.0009968102,"about_ca_topic_score_gemma":0.0048801485,"teacher_disagreement_score":0.006976802,"about_ca_system_score_codex":0.00009992447,"about_ca_system_score_gemma":0.0005766834,"threshold_uncertainty_score":0.99995404},"labels":[],"label_agreement":null},{"id":"W2033981208","doi":"10.4161/sysb.28948#.vojbffnf-4g","title":"Succumbing to the Laws of Attraction: Exploring the Sometimes Pathogenic Versatility of Discrete Immune Logic","year":2013,"lang":"en","type":"article","venue":"NSUWorks (Nova Southeastern University)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Attraction; Law; Political science; Philosophy","score_opus":0.030870369588020207,"score_gpt":0.21864437469270284,"score_spread":0.18777400510468265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033981208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98276114,0.00016225991,0.015521227,0.00028174382,0.00023658581,0.00027511554,0.00001651569,0.000007930348,0.00073749543],"genre_scores_gemma":[0.9986687,0.000031443426,0.00036273542,0.000031790398,0.000078528545,0.0000026129233,0.000009054804,0.000011655295,0.0008035191],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912965,0.00011448371,0.00019326428,0.00022402377,0.00014616761,0.00019240852],"domain_scores_gemma":[0.99919397,0.00003547289,0.00014477927,0.00045473577,0.0001223406,0.000048683552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024785346,0.0001255521,0.00016429847,0.00005722624,0.00013099049,0.000018294357,0.00041650177,0.000078777615,0.00016686128],"category_scores_gemma":[0.000029019206,0.00008620855,0.00016959468,0.0002376076,0.000085385036,0.000015868276,0.0002219994,0.00012486278,0.000018855746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019447586,0.000054344233,0.004043252,0.000031587526,0.0001806344,0.0000020818354,0.0014970646,0.0017226054,0.9805511,0.0009806756,0.000029265382,0.010712916],"study_design_scores_gemma":[0.0022353139,0.0011936296,0.032978415,0.00032770613,0.00035772528,0.00002075676,0.062277604,0.0008764514,0.8766392,0.00066416577,0.021383198,0.0010458267],"about_ca_topic_score_codex":0.00020785432,"about_ca_topic_score_gemma":0.00003859632,"teacher_disagreement_score":0.10391189,"about_ca_system_score_codex":0.000010250663,"about_ca_system_score_gemma":0.00002807717,"threshold_uncertainty_score":0.35154825},"labels":[],"label_agreement":null},{"id":"W2034110062","doi":"10.1016/j.jmb.2005.06.048","title":"Conformational Differences Between Arrestin2 and Pre-activated Mutants as Revealed by Hydrogen Exchange Mass Spectrometry","year":2005,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Eye Institute; National Institutes of Health; Cancer Research Society","keywords":"Arrestin; Mutant; Internalization; Chemistry; Receptor; Hydrogen–deuterium exchange; Ligand (biochemistry); G protein-coupled receptor; Biochemistry; Cell biology; Biophysics; Biology; Mass spectrometry","score_opus":0.008481236528564168,"score_gpt":0.2603003410422963,"score_spread":0.25181910451373213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034110062","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9774638,0.002766361,0.019057086,0.00029861715,0.000079717924,0.00009714444,0.00003345913,0.000004602186,0.00019922247],"genre_scores_gemma":[0.99476093,0.00042132149,0.004063257,0.00024754877,0.00034045323,0.000002806521,0.00006668985,0.000014853809,0.00008211968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988726,0.00013342267,0.0004207769,0.00018739155,0.00014654169,0.00023928248],"domain_scores_gemma":[0.9992236,0.000026765616,0.0003787795,0.00011727264,0.00010923262,0.00014433778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032153772,0.00017097141,0.00029709746,0.00010003899,0.000057557572,0.000022295157,0.0001993884,0.00023096429,0.00014019097],"category_scores_gemma":[0.00011756879,0.00014054899,0.00009726337,0.00007671339,0.00007482542,0.000010737762,0.000056745987,0.0001730273,0.0000038046558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008283118,0.000021454429,0.0036229563,0.000008225831,0.00016250114,0.0000060538828,0.00002860783,0.00000679847,0.9929449,0.000065358574,0.00017427868,0.00287605],"study_design_scores_gemma":[0.00075472967,0.00094852044,0.0012365968,0.000020464346,0.00003736358,0.00015810192,0.00002907961,0.000021772827,0.99032205,0.0008091258,0.0054841475,0.0001780434],"about_ca_topic_score_codex":0.000005367102,"about_ca_topic_score_gemma":7.245383e-7,"teacher_disagreement_score":0.017297158,"about_ca_system_score_codex":0.000018213623,"about_ca_system_score_gemma":0.00006229754,"threshold_uncertainty_score":0.5731422},"labels":[],"label_agreement":null},{"id":"W2034382007","doi":"10.2174/138955712800959134","title":"Biased Agonism of the Angiotensin II Type 1 Receptor","year":2012,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Angiotensin II; Signal transduction; Receptor; Functional selectivity; G protein-coupled receptor kinase; Cell biology; G protein; Agonist; Chemistry; Arrestin; Protein kinase A; Biology; Biochemistry; Kinase","score_opus":0.059845700104153195,"score_gpt":0.32093856464832643,"score_spread":0.26109286454417324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034382007","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006461033,0.99712706,0.000012320059,0.000036868976,0.0008616308,0.0006108584,0.00003475272,0.000005725533,0.0006646612],"genre_scores_gemma":[0.00019754391,0.99528956,0.0005529791,0.00011181378,0.0012998133,0.00006210918,0.00030791128,0.00006534885,0.0021129106],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972433,0.0002601678,0.001200688,0.0005383402,0.0003139927,0.00044349715],"domain_scores_gemma":[0.9979199,0.00004030926,0.0008174854,0.0010084136,0.00007027881,0.00014358603],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00121579,0.0005590071,0.0017779984,0.000040687413,0.00008208474,0.0000075208422,0.0008017321,0.0007917645,0.0007729042],"category_scores_gemma":[0.00040064778,0.00035233007,0.0007645933,0.0003893779,0.0001714972,0.0000029558412,0.0003275819,0.00056748476,0.000025405301],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017853614,0.00012284885,0.0000071873214,0.011667037,0.00011177936,0.0000029159194,0.000076229946,2.2257716e-7,0.13149522,0.000003490244,0.010555771,0.84593946],"study_design_scores_gemma":[0.00017216135,0.00006536931,7.2993475e-7,0.011283657,0.00039140583,0.000042911845,0.000020337457,3.937134e-7,0.03596902,0.000003380636,0.951717,0.00033364116],"about_ca_topic_score_codex":0.000009944002,"about_ca_topic_score_gemma":0.0000026519015,"teacher_disagreement_score":0.9411612,"about_ca_system_score_codex":0.00005839467,"about_ca_system_score_gemma":0.00033701892,"threshold_uncertainty_score":0.9998929},"labels":[],"label_agreement":null},{"id":"W2034784902","doi":"10.1210/me.2011-0018","title":"Mechanisms of Melanocortin-2 Receptor (MC2R) Internalization and Recycling in Human Embryonic Kidney (HEK) Cells: Identification of Key Ser/Thr (S/T) Amino Acids","year":2011,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Internalization; Biology; Cell biology; Endosome; Receptor; Melanocortin; HEK 293 cells; Intracellular; G protein-coupled receptor; Biochemistry; Signal transduction","score_opus":0.01229011126259249,"score_gpt":0.23966321955622666,"score_spread":0.22737310829363416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034784902","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8869777,0.00034163398,0.111926734,0.000020793135,0.00021582622,0.000230079,0.00001553454,0.000011517791,0.00026022262],"genre_scores_gemma":[0.9959756,0.00025399672,0.0033528497,0.000085152475,0.00001910947,0.000028635592,0.00012506692,0.000034149693,0.0001254497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829155,0.00017138572,0.0006593756,0.00045049048,0.00012949397,0.0002977045],"domain_scores_gemma":[0.9990083,0.0000071231234,0.00041825924,0.0003704639,0.00011908675,0.00007675613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002329211,0.00019457654,0.00031045274,0.00019249227,0.000037669914,0.00000846229,0.00025694497,0.00019962805,0.00010928517],"category_scores_gemma":[0.000090052396,0.00021202643,0.000096543445,0.00012903185,0.000098855315,0.000009630211,0.00016272243,0.000120560995,0.0000031668476],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006398228,0.00007993749,0.0010826943,0.000065576474,0.00005662397,0.000007741463,0.0002167284,0.000030911277,0.98798007,0.009733258,0.000018829354,0.0006636235],"study_design_scores_gemma":[0.00062806404,0.00039850507,0.00056982733,0.000046681274,0.000027716347,0.000015040396,0.00012667316,0.00010144105,0.99440336,0.003185581,0.00031766767,0.00017946075],"about_ca_topic_score_codex":0.00012590592,"about_ca_topic_score_gemma":0.000020453683,"teacher_disagreement_score":0.10899793,"about_ca_system_score_codex":0.000017501083,"about_ca_system_score_gemma":0.000041106374,"threshold_uncertainty_score":0.8646187},"labels":[],"label_agreement":null},{"id":"W2035290373","doi":"10.1038/nmeth0107-3","title":"BRET analysis of GPCR oligomerization: newer does not mean better","year":2006,"lang":"en","type":"letter","venue":"Nature Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"G protein-coupled receptor; Chemistry; Computational biology; Biophysics; Receptor; Biology; Cell biology; Biochemistry","score_opus":0.00962095491962426,"score_gpt":0.3151144376974683,"score_spread":0.305493482777844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035290373","genre_codex":"methods","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.018086107,0.0062490543,0.8564457,0.10707178,0.0057402514,0.0007615636,0.0013387632,0.00008431324,0.0042224317],"genre_scores_gemma":[0.0074283346,0.00014682536,0.45762038,0.5045655,0.0074950736,0.00003940111,0.011609825,0.0001876719,0.010907038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99750686,0.0005616672,0.00049597287,0.000722265,0.00038136038,0.00033186653],"domain_scores_gemma":[0.9984482,0.00008194086,0.00039419025,0.0007772221,0.00025471902,0.000043741642],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006735432,0.00040310354,0.00078526157,0.0003722123,0.000058400354,0.000040073344,0.0004303695,0.003245668,0.0005316549],"category_scores_gemma":[0.00008602222,0.00030085933,0.000724703,0.0005581092,0.000065789616,0.0000033722458,0.0001146027,0.0013491451,0.0000017232619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015522326,0.000014226524,0.00008234956,0.000065342094,0.0016519796,0.000010692951,0.000023004097,0.000079912126,0.78380626,0.000051545852,0.21054168,0.0036574518],"study_design_scores_gemma":[0.00010020311,0.000034287234,0.000059305203,0.000011484182,0.000918638,0.0000012421641,0.0000031700972,0.000062809166,0.50908303,0.00021871191,0.48923564,0.00027144788],"about_ca_topic_score_codex":0.000038050184,"about_ca_topic_score_gemma":0.000015161682,"teacher_disagreement_score":0.39882535,"about_ca_system_score_codex":0.000017503015,"about_ca_system_score_gemma":0.000052054856,"threshold_uncertainty_score":0.9999443},"labels":[],"label_agreement":null},{"id":"W2035591978","doi":"10.1016/j.bbrc.2003.09.154","title":"Type 1 angiotensin II receptor-associated protein ARAP1 binds and recycles the receptor to the plasma membrane","year":2003,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôtel-Dieu de Montréal; Université de Montréal","funders":"","keywords":"Receptor; Internalization; HEK 293 cells; Immunoprecipitation; Angiotensin II; G protein-coupled receptor; Cell biology; Molecular biology; Blot; Chemistry; Biology; Biochemistry; Gene","score_opus":0.049550763821074664,"score_gpt":0.31975957561759655,"score_spread":0.2702088117965219,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035591978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839005,0.0012289883,0.000019003792,0.01387552,0.000039634015,0.0005306163,0.00003361829,0.000014389773,0.00035775418],"genre_scores_gemma":[0.99582434,0.0012431818,0.0014204305,0.00021601602,0.00011367752,0.00010494887,0.000116535826,0.00001972659,0.0009411343],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981946,0.00057547254,0.0001934723,0.00035434795,0.00030861289,0.0003735355],"domain_scores_gemma":[0.9982943,0.00020549096,0.000043885528,0.00092701335,0.00033613498,0.00019315396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001061998,0.0001550699,0.00014765798,0.00004171576,0.001067551,0.00009527454,0.00065071177,0.00017967289,0.000036215217],"category_scores_gemma":[0.0014689616,0.00009219378,0.000059218153,0.0005204855,0.0005969969,0.0000058457476,0.0006495838,0.00043806172,0.000027686527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057586287,0.00012901518,0.000009975007,0.000004227039,0.00003790002,8.360102e-8,0.000091145615,3.5556914e-7,0.985142,0.0036903068,0.00932792,0.0015095158],"study_design_scores_gemma":[0.00017848553,0.00034750882,0.000050542494,0.000031835778,0.000008193415,0.0000018284848,0.00017832316,0.00007317951,0.7963953,0.00034997123,0.20224905,0.0001357541],"about_ca_topic_score_codex":0.00004905075,"about_ca_topic_score_gemma":0.000019147627,"teacher_disagreement_score":0.19292113,"about_ca_system_score_codex":0.000020708376,"about_ca_system_score_gemma":0.000081023354,"threshold_uncertainty_score":0.82108474},"labels":[],"label_agreement":null},{"id":"W2035962374","doi":"10.1159/000126256","title":"High Concentrations of Dopamine and Epinephrine Protect Dopaminergic D <sub>2</sub> Receptors from Inactivation by Phenoxybenzamine on Primary Cultured Rat Lactotrophs","year":2008,"lang":"en","type":"article","venue":"Neuroendocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Medical Research Council Canada","keywords":"Phenoxybenzamine; Dopaminergic; Endocrinology; Internal medicine; Dopamine; Dopamine receptor D2; Chemistry; Receptor; Epinephrine; Dopamine receptor; Biology; Medicine","score_opus":0.008094132160224848,"score_gpt":0.19469555057873528,"score_spread":0.18660141841851044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035962374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99678975,0.00067106995,0.0013695129,0.00026047163,0.0003658311,0.00038008558,0.000058625734,0.000031569376,0.00007308565],"genre_scores_gemma":[0.9936613,0.0040388512,0.0005803523,0.0003421483,0.00025368613,0.000056860852,0.0008556218,0.00003603804,0.00017517396],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984824,0.00016704392,0.00035853594,0.0005291174,0.00015200645,0.00031088304],"domain_scores_gemma":[0.9992655,0.00004279312,0.000215602,0.00029248398,0.000100135636,0.00008346463],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000015013211,0.0002641236,0.00033891597,0.00006612808,0.00012226675,0.000008984767,0.00013619308,0.00010910401,0.000039083472],"category_scores_gemma":[0.00009547585,0.0002435316,0.00006607177,0.00011741605,0.00016754941,0.000012252768,0.000086225475,0.00019232,0.0000038985268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024950207,0.00012811947,0.00037288893,0.000014251291,0.000042287582,0.000015571522,0.000020315929,0.00008715929,0.99306774,0.0001546235,0.0020393329,0.0038082052],"study_design_scores_gemma":[0.0014754691,0.0012005081,0.001180437,0.000011656765,0.00001880665,0.00006341561,0.00001703584,0.00002515406,0.98767847,0.000045206813,0.0080841435,0.00019970795],"about_ca_topic_score_codex":0.00006182106,"about_ca_topic_score_gemma":0.000007981418,"teacher_disagreement_score":0.0060448106,"about_ca_system_score_codex":0.000022439592,"about_ca_system_score_gemma":0.000041556617,"threshold_uncertainty_score":0.993093},"labels":[],"label_agreement":null},{"id":"W2035967600","doi":"10.1016/j.bbrc.2014.06.099","title":"μ–δ opioid receptor heteromer-specific signaling in the striatum and hippocampus","year":2014,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research; Ontario Mental Health Foundation","keywords":"Pertussis toxin; G protein-coupled receptor; Chemistry; G protein; Agonist; Pharmacology; Receptor; Striatum; Intrinsic activity; Gi alpha subunit; Neuroscience; Biology; Biochemistry; Dopamine","score_opus":0.05228513851364613,"score_gpt":0.32941339556307186,"score_spread":0.27712825704942573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035967600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956599,0.002246304,0.0001532406,0.0014466231,0.000020529584,0.00020525328,0.000010478989,0.0000069994626,0.0002507096],"genre_scores_gemma":[0.99527705,0.0025902854,0.0015920413,0.00012812803,0.00019716592,0.000062012696,0.000113697286,0.000011157692,0.000028475564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847114,0.00047580665,0.00018647325,0.0003188234,0.00024917207,0.0002985681],"domain_scores_gemma":[0.9987095,0.00032525085,0.000030397456,0.0007263274,0.00009528509,0.00011321776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010308196,0.000117162075,0.00013025911,0.000051134455,0.0002868022,0.00009932053,0.0006306824,0.00013047954,0.000012437204],"category_scores_gemma":[0.00022185975,0.00008335166,0.000043398362,0.00021457193,0.00050217565,0.000005994665,0.00042495248,0.00040915594,0.000009280043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027941622,0.0001065232,0.000056794805,0.000010392034,0.0000067725964,1.2018195e-7,0.00007106506,1.8178143e-7,0.9858037,0.0034138272,0.0009565155,0.009546114],"study_design_scores_gemma":[0.0007793586,0.0006454397,0.0007646419,0.00008148276,0.000008207859,0.0000063552616,0.0007296654,0.0005461563,0.861014,0.009993607,0.12508984,0.00034125],"about_ca_topic_score_codex":0.000034089084,"about_ca_topic_score_gemma":0.000004359185,"teacher_disagreement_score":0.12478976,"about_ca_system_score_codex":0.00001042028,"about_ca_system_score_gemma":0.000022507385,"threshold_uncertainty_score":0.3398982},"labels":[],"label_agreement":null},{"id":"W2036009746","doi":"10.1016/j.bmcl.2011.06.106","title":"Synthesis and in vitro evaluation of derivatives of the β1-adrenergic receptor antagonist HX-CH 44","year":2011,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Antagonist; In vitro; Quinazolinone; Isopropyl; Receptor; Adrenergic receptor; Stereochemistry; Adrenergic; Receptor antagonist; Adrenergic antagonist; Chemical synthesis; Medicinal chemistry; Biochemistry","score_opus":0.02200311012076418,"score_gpt":0.23176206868836302,"score_spread":0.20975895856759885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036009746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987305,0.00053331815,0.000076317265,0.00022216018,0.00008971624,0.00012278871,0.00001366209,0.0000028448162,0.00020873429],"genre_scores_gemma":[0.99933547,0.00006621227,0.00033002975,0.00010987027,0.00009977947,0.00001329824,0.000018163166,0.00001540551,0.0000117697555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875665,0.00011122341,0.0003568713,0.00027708113,0.00033898413,0.00015917636],"domain_scores_gemma":[0.99930334,0.000023605724,0.00024400363,0.00029824054,0.00008294358,0.000047852038],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069004024,0.0001507098,0.00022649587,0.000022133785,0.00003744508,0.0000039621987,0.00023323647,0.00011853315,0.00033981405],"category_scores_gemma":[0.0002890546,0.000112775015,0.00006998437,0.00012446863,0.0002273576,0.0000040787377,0.00007778958,0.00009173482,4.227916e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011564851,0.000037530823,0.0011299986,0.00005995516,0.000037949092,4.975277e-7,0.00021881764,0.0000016081169,0.99742204,0.0000020101784,0.000067154506,0.0009067771],"study_design_scores_gemma":[0.0004139086,0.00001921872,0.0021873098,0.000073703144,0.00006114168,0.000008513218,0.0004750089,0.000024465595,0.9965492,0.000014082795,0.00006095773,0.00011251506],"about_ca_topic_score_codex":0.000042372987,"about_ca_topic_score_gemma":0.0000020843975,"teacher_disagreement_score":0.0010573113,"about_ca_system_score_codex":0.000026085145,"about_ca_system_score_gemma":0.000088959176,"threshold_uncertainty_score":0.45988315},"labels":[],"label_agreement":null},{"id":"W2037185437","doi":"10.1074/jbc.m009375200","title":"Role of the Differentially Spliced Carboxyl Terminus in Thromboxane A2 Receptor Trafficking","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Internalization; Dynamin; Receptor; Cell biology; Chemistry; Agonist; Gene isoform; G protein-coupled receptor; GTPgammaS; Biochemistry; Biophysics; Biology; Endocytosis","score_opus":0.01237017755364301,"score_gpt":0.2306155757995963,"score_spread":0.2182453982459533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037185437","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99841946,0.0007119911,0.000062966,0.000060476053,0.00015085406,0.00005785404,0.000004418099,0.0000026878238,0.0005292942],"genre_scores_gemma":[0.99880606,0.00035075526,0.00023163138,0.000041029565,0.00046650853,0.0000017980375,0.000006788055,0.000009123454,0.000086321495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891746,0.000058169393,0.00049185386,0.00017267058,0.00015798633,0.00020183064],"domain_scores_gemma":[0.99926096,0.000021835318,0.00038036343,0.00018216339,0.00008631568,0.0000683848],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000261186,0.00014462523,0.00028686994,0.000016388864,0.000033451313,0.000012000451,0.000396385,0.0002728281,0.00022912672],"category_scores_gemma":[0.00013784881,0.000086346176,0.00024422267,0.00009820625,0.00007824656,0.0000033648064,0.00009713034,0.00024115678,5.4540254e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012289507,0.00010424937,0.004919542,0.000009970819,0.000029068375,0.00000541358,0.000031305477,0.000047181533,0.99293417,0.000004281457,0.00003888283,0.001753063],"study_design_scores_gemma":[0.0004661172,0.00016910784,0.004584553,0.000060874634,0.000011110128,0.000108355925,0.00018901684,0.000016358046,0.9923602,0.00008526544,0.0018358341,0.00011321593],"about_ca_topic_score_codex":0.0000042839683,"about_ca_topic_score_gemma":0.0000025926877,"teacher_disagreement_score":0.0017969514,"about_ca_system_score_codex":0.000021159545,"about_ca_system_score_gemma":0.00005749728,"threshold_uncertainty_score":0.35210946},"labels":[],"label_agreement":null},{"id":"W2037202267","doi":"10.1016/j.pnpbp.2010.03.030","title":"Cocaine and amphetamine regulated transcript (CART) gene in the comorbidity of schizophrenia with alcohol use disorders and nicotine dependence","year":2010,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Cart; Nicotine; Schizophrenia (object-oriented programming); Addiction; Amphetamine; Alcohol dependence; Genetic predisposition; Cocaine and amphetamine regulated transcript; Psychiatry; Psychosis; Genetic association; Psychology; Medicine; Alcohol; Gene; Genetics; Dopamine; Internal medicine; Single-nucleotide polymorphism; Biology; Genotype","score_opus":0.01419681700302243,"score_gpt":0.27196430453945564,"score_spread":0.2577674875364332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037202267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99514073,0.0030050206,0.000028264147,0.0010018349,0.00033782184,0.00045030902,0.000016866741,0.000009291625,0.0000098388555],"genre_scores_gemma":[0.99482596,0.0028378312,0.0016178414,0.0005480584,0.00008380482,0.000046942176,0.000025083977,0.000011341356,0.0000031487832],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99861085,0.00022233879,0.00029161162,0.0005295611,0.00008213159,0.0002635128],"domain_scores_gemma":[0.9995478,0.00007509199,0.0001060378,0.00016952404,0.000027486238,0.000074081785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037261157,0.00022116496,0.0002547879,0.00006116788,0.00007927891,0.000021509612,0.0001882024,0.00027568708,0.000015806983],"category_scores_gemma":[0.000029172634,0.00013640792,0.00003371292,0.00015666407,0.00069208996,0.000011803347,0.00006106884,0.0004425663,1.1506098e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017032359,0.00024504,0.6443357,0.000020246087,0.000022259772,0.0000050341705,0.000030789997,0.0000020771763,0.3496205,0.00022693363,0.000025927455,0.0037622552],"study_design_scores_gemma":[0.0064743934,0.0016262655,0.97614855,0.000021405855,0.000035863737,0.00014721385,0.000060919625,0.00013039766,0.0137392655,0.0006923877,0.0006587066,0.00026462958],"about_ca_topic_score_codex":0.000010658858,"about_ca_topic_score_gemma":0.00027306058,"teacher_disagreement_score":0.33588123,"about_ca_system_score_codex":0.000001192095,"about_ca_system_score_gemma":0.00001936802,"threshold_uncertainty_score":0.55625534},"labels":[],"label_agreement":null},{"id":"W2037343509","doi":"10.1021/bi034491m","title":"Monomers and Oligomers of the M<sub>2</sub> Muscarinic Cholinergic Receptor Purified from <i>Sf</i>9 Cells","year":2003,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Centre for Addiction and Mental Health","keywords":"Receptor; Immunoprecipitation; Sepharose; Chemistry; Sf9; Muscarinic acetylcholine receptor; Chaps; Affinity chromatography; Monomer; Biochemistry; Digitonin; Muscarinic acetylcholine receptor M1; Molecular biology; Chromatography; Recombinant DNA; Biology; Membrane; Enzyme","score_opus":0.005713073942117083,"score_gpt":0.18382305091609955,"score_spread":0.17810997697398245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037343509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968087,0.0018380653,0.00006601535,0.000029050068,0.00032886112,0.00011599933,0.000058395417,0.000009008807,0.00074587937],"genre_scores_gemma":[0.99830973,0.00065262103,0.00043050485,0.00012353252,0.00015298791,0.000013693631,0.000057892812,0.000029149152,0.00022988167],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884605,0.000051262206,0.00027136572,0.00044135825,0.00014583798,0.00024410558],"domain_scores_gemma":[0.9991628,0.000015933416,0.0001626601,0.00049073115,0.000052758965,0.00011514126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014722058,0.00021445245,0.00019352497,0.000016402337,0.000077091376,0.000019665917,0.00023572643,0.00027028614,0.00005665332],"category_scores_gemma":[0.00006182835,0.00017932967,0.00015515086,0.00010248355,0.00012937933,0.0000031979405,0.00009668948,0.00012927706,0.0000044732296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022902961,0.00003218352,0.0002170558,0.000023758672,0.000051939172,3.3745252e-7,0.000026803973,0.00002030776,0.99827725,0.000015277868,0.0008327957,0.00047941305],"study_design_scores_gemma":[0.00042732665,0.00003214511,0.000065078675,0.000022947017,0.000025248606,0.0000027242509,0.00014956397,0.000008545763,0.9949238,0.000044495242,0.0040836995,0.00021444727],"about_ca_topic_score_codex":0.000016341288,"about_ca_topic_score_gemma":0.0000015206843,"teacher_disagreement_score":0.003353446,"about_ca_system_score_codex":0.000014402268,"about_ca_system_score_gemma":0.00008997537,"threshold_uncertainty_score":0.73128515},"labels":[],"label_agreement":null},{"id":"W2037368323","doi":"10.1021/cn200096u","title":"Transformation of Pro-Leu-Gly-NH<sub>2</sub> Peptidomimetic Positive Allosteric Modulators of the Dopamine D<sub>2</sub> Receptor into Negative Modulators","year":2012,"lang":"en","type":"article","venue":"ACS Chemical Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Allosteric regulation; Allosteric modulator; Chemistry; Stereochemistry; Peptidomimetic; Steric effects; Dopamine; Receptor; Biochemistry; Biology; Neuroscience; Peptide","score_opus":0.0086222715302548,"score_gpt":0.21935833874430574,"score_spread":0.21073606721405094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037368323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99707764,0.00008531462,0.0017447413,0.00007615094,0.00042741813,0.000486662,0.00003032454,0.000013279488,0.000058492882],"genre_scores_gemma":[0.99920064,0.000084210675,0.00033449192,0.00018175945,0.000109338034,0.000029780522,0.000022275684,0.000030950156,0.000006538172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979219,0.00012897761,0.000537084,0.00046767225,0.00048323596,0.00046114257],"domain_scores_gemma":[0.998843,0.00004798912,0.00033826043,0.00041808226,0.00017427138,0.00017837941],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033814198,0.00028981396,0.00031366816,0.00006570849,0.0001209123,0.000020590984,0.0005105855,0.00019563742,0.0000037750724],"category_scores_gemma":[0.00033187162,0.00022602019,0.00020217235,0.00050746236,0.00047036362,0.000062679785,0.00022070429,0.00020194383,0.000003206522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000837165,0.00013375471,0.00024268149,0.000044485838,0.00001149883,1.7498327e-7,0.0004199036,0.00010773006,0.9971008,0.00011670488,0.0000209195,0.0017176535],"study_design_scores_gemma":[0.000406088,0.00023133228,0.0007453621,0.000052006482,0.000029376162,0.000010065908,0.000089857356,0.00046594391,0.9975701,0.00011973201,0.000035745965,0.00024441959],"about_ca_topic_score_codex":0.0000071693553,"about_ca_topic_score_gemma":8.175105e-7,"teacher_disagreement_score":0.0021230392,"about_ca_system_score_codex":0.000038584814,"about_ca_system_score_gemma":0.00007143001,"threshold_uncertainty_score":0.92168355},"labels":[],"label_agreement":null},{"id":"W2037380951","doi":"10.1016/j.febslet.2004.09.059","title":"Role of the fourth intracellular loop of D1‐like dopaminergic receptors in conferring subtype‐specific signaling properties","year":2004,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Receptor; Dopamine receptor; Dopaminergic; Intracellular; Cell biology; Dopamine; Biology; Endocrinology; Biochemistry","score_opus":0.010001491365019525,"score_gpt":0.18516497777733104,"score_spread":0.17516348641231153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037380951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99700713,0.001296806,0.00097366935,0.00024611256,0.00023467548,0.0001755175,0.0000024039525,0.0000055903365,0.000058088954],"genre_scores_gemma":[0.9989559,0.00007194076,0.0005802204,0.00020525766,0.00009780993,0.000008935747,0.000009402857,0.000022986886,0.00004756747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989957,0.000059269085,0.00032207445,0.00023687643,0.00016970313,0.00021636863],"domain_scores_gemma":[0.9994899,0.0000061495007,0.00015725306,0.00026803443,0.000046866433,0.000031783617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020288282,0.000144785,0.00019083882,0.00005686114,0.000041430976,0.000012281435,0.00025464973,0.00009355076,0.00003422376],"category_scores_gemma":[0.000017087033,0.00010957334,0.0001156366,0.00012795262,0.00009947987,0.00000600717,0.00007816551,0.000120213925,0.0000019143988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047493755,0.000033113567,0.001029942,0.000026384974,0.000023557515,0.0000013008495,0.00024099549,0.018420866,0.9797538,0.00012146198,0.00003180363,0.00026931782],"study_design_scores_gemma":[0.00044254118,0.00007298149,0.00012293483,0.00011351675,0.000009239267,0.0000032311018,0.00038702018,0.000052424537,0.9970747,0.00005218089,0.0015338382,0.0001353739],"about_ca_topic_score_codex":0.0001052322,"about_ca_topic_score_gemma":0.000025032608,"teacher_disagreement_score":0.018368442,"about_ca_system_score_codex":0.000024454275,"about_ca_system_score_gemma":0.000046399993,"threshold_uncertainty_score":0.4468271},"labels":[],"label_agreement":null},{"id":"W2037404289","doi":"10.1074/jbc.m112.396259","title":"Extracellular Ionic Locks Determine Variation in Constitutive Activity and Ligand Potency between Species Orthologs of the Free Fatty Acid Receptors FFA2 and FFA3","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Wellcome Trust; Canadian Institutes of Health Research; Strategiske Forskningsråd","keywords":"Extracellular; Potency; Receptor; Chemistry; Ligand (biochemistry); Variation (astronomy); Biochemistry; Biology; Cell biology; In vitro","score_opus":0.01989910896039843,"score_gpt":0.22994879908275542,"score_spread":0.210049690122357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037404289","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955086,0.0032382507,0.0009044729,0.0000694953,0.000091801216,0.000062243045,0.000013365223,0.0000015181641,0.00011025091],"genre_scores_gemma":[0.9984878,0.0005756633,0.0006209762,0.000009338264,0.000248376,0.000001166816,0.0000035474206,0.0000041608914,0.000049027436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921757,0.000070811504,0.00030556254,0.00014092696,0.00009953966,0.00016556862],"domain_scores_gemma":[0.9993367,0.00004419687,0.00034317718,0.00013103464,0.00006383142,0.000081043894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048712964,0.00012562633,0.0002490811,0.000016031985,0.00005098352,0.000010252467,0.0001503472,0.00028545916,0.000031172058],"category_scores_gemma":[0.00036159603,0.00007760827,0.00008159369,0.000056950084,0.00022246329,0.00001189682,0.00014565489,0.00022526704,9.511368e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056063156,0.00004114144,0.099122606,0.00001569914,0.00002438992,0.0000015431781,0.000046563593,0.0000022706856,0.89979255,0.000011105864,0.0000072117355,0.00087886705],"study_design_scores_gemma":[0.000386763,0.00012744188,0.11039746,0.000032337564,0.000020534373,0.00005972988,0.000077682074,0.0000020326827,0.88847345,0.00015062114,0.00018461983,0.00008733363],"about_ca_topic_score_codex":0.0000036575686,"about_ca_topic_score_gemma":0.0000010229045,"teacher_disagreement_score":0.01131909,"about_ca_system_score_codex":0.000015800539,"about_ca_system_score_gemma":0.000036331156,"threshold_uncertainty_score":0.31647733},"labels":[],"label_agreement":null},{"id":"W2037525657","doi":"10.1016/j.cellsig.2004.12.001","title":"Dissociation of β-arrestin from internalized bradykinin B2 receptor is necessary for receptor recycling and resensitization","year":2005,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Victoria Hospital; McGill University; Montreal Clinical Research Institute","funders":"","keywords":"Endosome; Internalization; G protein-coupled receptor; Arrestin; Receptor; Cell biology; Agonist; Bradykinin; Chemistry; Enzyme-linked receptor; Biology; Biochemistry","score_opus":0.013098431769535719,"score_gpt":0.24494165182082728,"score_spread":0.23184322005129157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037525657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.792843,0.0015826658,0.20475027,0.00023594966,0.00021764613,0.00023813338,0.00006458627,0.000015968879,0.00005180499],"genre_scores_gemma":[0.96696645,0.00037618936,0.03029423,0.00016312923,0.00093312236,0.000018670504,0.0008028869,0.00004887852,0.00039641498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985936,0.00009843854,0.00046465284,0.0004433318,0.00017559048,0.00022438304],"domain_scores_gemma":[0.99916124,0.00009489331,0.00031585916,0.00017509508,0.00016909046,0.00008383079],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004622843,0.00018752372,0.0002589276,0.000059893533,0.000117081196,0.000045638826,0.0001397643,0.00023247483,0.00017671785],"category_scores_gemma":[0.0001869686,0.00019935942,0.00012655868,0.00008154936,0.000036250065,0.000016513324,0.00005958883,0.00009738472,0.000004518966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017769459,0.000030413166,0.0005672684,0.000027385744,0.00007223448,2.8434627e-7,0.00032408544,0.0003415404,0.9906085,0.00006130176,0.00076361804,0.0070256875],"study_design_scores_gemma":[0.0007568707,0.00012056059,0.00001774305,0.00013178348,0.0000386384,4.3412e-7,0.00022042386,0.00743327,0.98071223,0.00031726927,0.010026795,0.00022394948],"about_ca_topic_score_codex":0.000034795114,"about_ca_topic_score_gemma":0.000007666689,"teacher_disagreement_score":0.17445605,"about_ca_system_score_codex":0.000024172443,"about_ca_system_score_gemma":0.00003561857,"threshold_uncertainty_score":0.8129641},"labels":[],"label_agreement":null},{"id":"W2037851184","doi":"10.1074/jbc.m111811200","title":"Distinct Residues in the Carboxyl Tail Mediate Agonist-induced Desensitization and Internalization of the Human Dopamine D1 Receptor","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Internalization; Desensitization (medicine); Agonist; Dopamine; Endogenous agonist; Receptor; Chemistry; Dopamine receptor D1; Dopamine receptor; Pharmacology; Neuroscience; Cell biology; Endocrinology; Psychology; Medicine; Biology; Biochemistry","score_opus":0.0255368275309994,"score_gpt":0.2453653329964508,"score_spread":0.2198285054654514,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2037851184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99890965,0.00039017218,0.00015681228,0.00017157302,0.000054727894,0.00006839521,0.000004286849,0.0000015649515,0.00024280271],"genre_scores_gemma":[0.99932003,0.00022231451,0.00006899339,0.00005863093,0.00025992954,0.0000023005882,0.000014083968,0.0000054254165,0.00004827103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991685,0.00011440463,0.0003558298,0.000119842625,0.00013787043,0.00010351031],"domain_scores_gemma":[0.99938,0.00003080336,0.00033339753,0.00012483606,0.00009769918,0.000033285618],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037585772,0.0000982957,0.00015146575,0.000012306804,0.000057018464,0.000017954835,0.00021946055,0.0001482039,0.00007148097],"category_scores_gemma":[0.00029839977,0.000050621908,0.000079363046,0.0000790913,0.00008445263,0.0000040131927,0.000058731963,0.00015516911,2.1039443e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002234055,0.000041719122,0.007864324,0.000013518964,0.000012280918,0.0000026809394,0.00006250606,0.0000050773488,0.99138916,0.000015310998,0.000095928444,0.00047514643],"study_design_scores_gemma":[0.00031265352,0.0001705316,0.0047988356,0.000054273816,0.000010252699,0.000047513662,0.00015254809,0.000039316663,0.99368083,0.00014889042,0.0005114809,0.00007286958],"about_ca_topic_score_codex":0.0000061325895,"about_ca_topic_score_gemma":0.000004727614,"teacher_disagreement_score":0.0030654892,"about_ca_system_score_codex":0.000012628086,"about_ca_system_score_gemma":0.000010356777,"threshold_uncertainty_score":0.20643015},"labels":[],"label_agreement":null},{"id":"W2038032704","doi":"10.1016/j.bpj.2010.12.1948","title":"Identification of hPXR Modulators via SAR-Based Virtual Screening","year":2011,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Luciferase; Virtual screening; Computational biology; Pharmacology; Chemistry; Drug discovery; Biochemistry; Biology; Transfection","score_opus":0.01699845859834704,"score_gpt":0.2350207100026277,"score_spread":0.21802225140428066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038032704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6887645,0.000014853719,0.3109992,0.000008021054,0.0001413045,0.00003189474,0.0000026352088,0.0000037910181,0.000033746306],"genre_scores_gemma":[0.99651414,0.0000066947705,0.0029896735,0.000040029256,0.0003766459,0.0000011717251,0.000009201465,0.00001511138,0.00004731039],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991901,0.000048121383,0.00028490738,0.00015632345,0.00017215079,0.00014840196],"domain_scores_gemma":[0.9994396,0.000004604343,0.0002015893,0.00015265086,0.00010836532,0.000093191135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001819165,0.00009962882,0.00012013377,0.00004083884,0.00007603563,0.000016824397,0.00016402117,0.0000872023,0.000067045024],"category_scores_gemma":[0.00002166689,0.000087310196,0.00015637596,0.00006576858,0.00005066356,0.000006318449,0.00002890894,0.000101718295,0.000006007369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007338462,0.000087647335,0.0001770245,0.0000031603674,0.000030507352,0.0000013743905,0.000033513676,0.00023916067,0.9941294,0.0002386354,0.000032009582,0.0049541714],"study_design_scores_gemma":[0.00027071591,0.00034425477,0.0013367087,0.000010649072,0.000017514112,0.0000092805285,0.00003486071,0.0029492434,0.9946549,0.00014124982,0.00012474082,0.00010590594],"about_ca_topic_score_codex":0.000004430294,"about_ca_topic_score_gemma":1.9871656e-7,"teacher_disagreement_score":0.30800954,"about_ca_system_score_codex":0.000006101527,"about_ca_system_score_gemma":0.000027917476,"threshold_uncertainty_score":0.35604063},"labels":[],"label_agreement":null},{"id":"W2038070777","doi":"10.1210/en.2009-0826","title":"Role of Asparagine-Linked Glycosylation in Cell Surface Expression and Function of the Human Adrenocorticotropin Receptor (Melanocortin 2 Receptor) in 293/FRT Cells","year":2009,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Glycosylation; Tunicamycin; N-linked glycosylation; Receptor; Biology; Melanocortin; Chinese hamster ovary cell; Mutant; G protein-coupled receptor; HEK 293 cells; Asparagine; Cell biology; Biochemistry; Molecular biology; Glycoprotein; Endoplasmic reticulum; Gene; Amino acid; Unfolded protein response","score_opus":0.006672473486117554,"score_gpt":0.22089188113638467,"score_spread":0.21421940765026712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038070777","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99821055,0.0007530698,0.00021408134,0.00004892061,0.00014945399,0.00026203354,0.0000051064376,0.000005720769,0.00035108687],"genre_scores_gemma":[0.99873555,0.00020766276,0.0007752465,0.000025019677,0.000046625708,0.000007302809,0.000030205514,0.000011157843,0.00016122818],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987586,0.00015644026,0.00043583108,0.0002922298,0.00009767818,0.0002592011],"domain_scores_gemma":[0.9994309,0.0000142525105,0.00023750038,0.00024508647,0.000041198185,0.000031048177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001026105,0.00013787395,0.00022805223,0.00007256034,0.000036734054,0.000004245689,0.00014035168,0.00015703926,0.00009842286],"category_scores_gemma":[0.000024505714,0.00011698126,0.000054459444,0.000121892015,0.000050168626,0.0000069738403,0.00007093273,0.00015204068,0.000001695725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012764739,0.00009343311,0.010695268,0.0000127485255,0.0000042495244,3.4494627e-7,0.000106058076,0.00075119553,0.9863541,0.00013925174,0.0000636252,0.0016520728],"study_design_scores_gemma":[0.00085997547,0.00042055376,0.031457946,0.000031648095,0.0000056977824,0.0000013986274,0.000108037326,0.00007354221,0.96575296,0.0003412685,0.0008410723,0.00010590563],"about_ca_topic_score_codex":0.00005731671,"about_ca_topic_score_gemma":0.000039729402,"teacher_disagreement_score":0.020762676,"about_ca_system_score_codex":0.000017611781,"about_ca_system_score_gemma":0.000031188054,"threshold_uncertainty_score":0.47703573},"labels":[],"label_agreement":null},{"id":"W2038206601","doi":"10.1210/endo.141.12.7856","title":"Adrenergic Regulation of Mitogen-Activated Protein Kinase in Rat Pinealocytes: Opposing Effects of Protein Kinase A and Protein Kinase G**This work was supported by grants from the Medical Research Council of Canada.","year":2000,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Protein kinase A; Mitogen-activated protein kinase kinase; MAP2K7; Protein kinase C; MAP kinase kinase kinase; Cyclin-dependent kinase 2; ASK1; MAPK/ERK pathway; Protein phosphorylation; Cyclin-dependent kinase 9; cGMP-dependent protein kinase; Protein kinase inhibitor; Biology; Internal medicine; Phosphorylation; Chemistry; Endocrinology; Cell biology; Medicine","score_opus":0.01844234744721657,"score_gpt":0.2454547264643531,"score_spread":0.22701237901713653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038206601","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994505,0.003569001,0.00004394765,0.000266924,0.00006336397,0.0014261968,0.00004408147,0.0000069900007,0.00007448188],"genre_scores_gemma":[0.9986148,0.00010218045,0.00022112163,0.00003021369,0.00005693529,0.00022686803,0.000109857414,0.000028507891,0.0006095338],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967021,0.0008005132,0.00060076074,0.00049096695,0.0008647112,0.00054097146],"domain_scores_gemma":[0.9987045,0.00011776575,0.00021605766,0.0004395101,0.0003894583,0.00013271213],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000712779,0.00023096615,0.00044209062,0.00007264685,0.000098075914,0.000009095737,0.00030775642,0.0002679002,0.00038641854],"category_scores_gemma":[0.0010079177,0.00018849707,0.000058040827,0.00035373386,0.00035408128,0.000008819922,0.00011473834,0.0003248092,5.368293e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010570366,0.00014511705,0.00013267974,0.00012903137,0.00006047272,0.00006725714,0.00020198974,0.000017270184,0.99055547,0.000053785596,0.00042115586,0.0071587674],"study_design_scores_gemma":[0.0020333647,0.00052474963,0.0002691974,0.00049727096,0.000012667779,0.000007790366,0.00007746235,0.00008916929,0.99245596,0.00012258733,0.0037457957,0.0001639936],"about_ca_topic_score_codex":0.08619471,"about_ca_topic_score_gemma":0.02387627,"teacher_disagreement_score":0.062318437,"about_ca_system_score_codex":0.00013907264,"about_ca_system_score_gemma":0.0018473412,"threshold_uncertainty_score":0.99393547},"labels":[],"label_agreement":null},{"id":"W2038465216","doi":"10.1080/10408360591001895","title":"The G protein-coupled receptors: Pharmacogenetics and Disease","year":2005,"lang":"en","type":"review","venue":"Critical Reviews in Clinical Laboratory Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Receptor; Biology; Pharmacogenetics; Pharmacology; Genetics; Gene; Genotype","score_opus":0.12001803448919529,"score_gpt":0.47833276111375267,"score_spread":0.3583147266245574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038465216","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000094506824,0.99749374,0.00008359084,0.0002704549,0.0008114453,0.00114385,0.000030514644,0.000008442079,0.00006348102],"genre_scores_gemma":[0.000034977747,0.9962849,0.0015870497,0.0004940703,0.0011355315,0.0002965441,0.000013850449,0.000029779521,0.00012326745],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9947051,0.0015905095,0.0018247165,0.0010276927,0.00032011486,0.0005319034],"domain_scores_gemma":[0.99755293,0.0009120958,0.00030780365,0.0005094715,0.00012286054,0.0005948387],"candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00763205,0.00042767354,0.0012200896,0.00004961548,0.00037034941,0.00020481936,0.0008506107,0.0003663545,0.00008680326],"category_scores_gemma":[0.017279511,0.0002499133,0.0004322983,0.00045576112,0.0017526691,0.000011622911,0.0002911568,0.0005650479,0.00004901519],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008737491,0.00006766284,0.000016420783,0.0014302499,0.000013500367,0.000004207941,0.0000017160972,2.3037428e-7,0.000040934672,0.001603029,0.0009954323,0.9958179],"study_design_scores_gemma":[0.000090355185,0.00016240044,0.0000013327596,0.0038267227,0.00012596819,0.0000014502739,0.000006557996,0.000023809014,0.000011587033,0.0002974549,0.995115,0.000337373],"about_ca_topic_score_codex":6.1090896e-7,"about_ca_topic_score_gemma":0.00000524341,"teacher_disagreement_score":0.9954805,"about_ca_system_score_codex":0.000019335659,"about_ca_system_score_gemma":0.0010315331,"threshold_uncertainty_score":0.9999953},"labels":[],"label_agreement":null},{"id":"W2038522229","doi":"10.1111/j.1440-1681.2004.04037.x","title":"ARTERIAL STRUCTURAL CHANGES IN HYPERTENSIVE RATS INDUCED BY CAPSAICIN AND SALT LOADING","year":2004,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Capsaicin; Blood pressure; Saline; Medicine; Internal medicine; Artery; Aorta; Perfusion; Endocrinology; Weaning; Anesthesia","score_opus":0.024044817829127527,"score_gpt":0.33994921298683334,"score_spread":0.3159043951577058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038522229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960141,0.0028572003,0.000003738036,0.00028698216,0.0006603425,0.00015010116,0.000008982778,0.000005761389,0.000012800657],"genre_scores_gemma":[0.99649125,0.0006398362,0.00006505804,0.0022808486,0.00044012556,0.00001949055,0.000042744097,0.00000981146,0.000010853796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998995,0.000111870286,0.00021194032,0.0004271872,0.000027077267,0.00022689626],"domain_scores_gemma":[0.9997258,0.000031829837,0.000055995763,0.000055258446,0.000014061902,0.00011703196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009944642,0.00016028945,0.00030054784,0.000022809942,0.0000983849,0.000008948371,0.000052911662,0.00025452988,0.00005782058],"category_scores_gemma":[0.000011263773,0.00013755566,0.000028122573,0.000023979966,0.00030948434,0.000006438929,0.00012520829,0.00016191925,0.0000010012434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054976565,0.000055062403,0.00024998593,0.000005924082,0.00003602031,0.000004183123,0.00013364243,0.000002066051,0.9980863,0.00005106846,0.00017185583,0.0006541404],"study_design_scores_gemma":[0.003008559,0.0011622552,0.0019434431,0.000006176804,0.000013530481,0.000024274585,0.00024261123,0.000032662363,0.99241066,0.0005640388,0.00041618632,0.00017559942],"about_ca_topic_score_codex":0.000042467545,"about_ca_topic_score_gemma":0.00001437282,"teacher_disagreement_score":0.0056756227,"about_ca_system_score_codex":0.000005113825,"about_ca_system_score_gemma":0.000015481448,"threshold_uncertainty_score":0.5609357},"labels":[],"label_agreement":null},{"id":"W2038586219","doi":"10.1155/2014/413921","title":"Association of Immune and Metabolic Receptors<i>C5aR</i>and<i>C5L2</i>with Adiposity in Women","year":2014,"lang":"en","type":"article","venue":"Mediators of Inflammation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Canadian Institutes of Health Research","keywords":"Adipose tissue; Internal medicine; Receptor; Adiponectin; Endocrinology; Waist; Immune system; Medicine; Body mass index; Receptor expression; Overweight; Obesity; Immunology; Insulin resistance","score_opus":0.001796130925731614,"score_gpt":0.17667768550041463,"score_spread":0.17488155457468302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038586219","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99877924,0.0004113275,0.00049562677,0.000060318445,0.00006855773,0.00010532245,0.0000022269228,0.0000035897933,0.000073769246],"genre_scores_gemma":[0.9988141,0.00041715405,0.0006002312,0.000011876098,0.00007471385,0.0000139620515,0.000019507806,0.00000820168,0.00004025581],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926054,0.000081426304,0.00027652187,0.00013007755,0.00013539674,0.00011604311],"domain_scores_gemma":[0.9994761,0.000028299617,0.00027841283,0.00009913334,0.000079601174,0.000038502596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007604229,0.00008235135,0.00019299825,0.000064449734,0.000019758192,0.0000064127944,0.00004833916,0.00011032842,0.000011553863],"category_scores_gemma":[0.00020028671,0.00007213703,0.000020206806,0.00006646066,0.000026567308,0.000010277836,0.000030461117,0.00004853997,3.6787605e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084504085,0.00001282403,0.03223783,0.000045608267,0.00004070782,5.213123e-8,0.0006109817,0.000032492513,0.9584638,0.00028306787,0.00001109592,0.008177069],"study_design_scores_gemma":[0.00074478035,0.00018930242,0.026457936,0.000026969348,0.000017796809,5.299399e-7,0.00008685448,0.000104768886,0.9705094,0.0002565457,0.0015154649,0.00008962868],"about_ca_topic_score_codex":0.000033499357,"about_ca_topic_score_gemma":0.000028202032,"teacher_disagreement_score":0.012045656,"about_ca_system_score_codex":0.000013889968,"about_ca_system_score_gemma":0.0000188493,"threshold_uncertainty_score":0.29416627},"labels":[],"label_agreement":null},{"id":"W2038722042","doi":"10.1016/s0895-7061(03)00482-5","title":"Dose-dependant effects of ace-inhibition on the cardiovascular actions of human ?new pressor protein? (NPP) related to $beta;FXIIA","year":2003,"lang":"en","type":"article","venue":"American Journal of Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heart and Stroke Foundation; University of Toronto","funders":"","keywords":"Blood pressure; Internal medicine; Medicine; Bradykinin; Captopril; Heart rate; Endocrinology; Endogeny; Receptor","score_opus":0.01572952145132456,"score_gpt":0.2344244706141628,"score_spread":0.21869494916283824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038722042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997422,0.00065622147,0.0011862236,0.00022491162,0.00012742732,0.00029498345,0.0000015188441,0.00000310396,0.00008365918],"genre_scores_gemma":[0.9986613,0.000085582666,0.0009978184,0.00011100625,0.000053419873,0.000004520188,0.0000023783089,0.000022430006,0.000061557716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987172,0.00027785145,0.00037793515,0.00016598833,0.00031247723,0.0001485837],"domain_scores_gemma":[0.99892044,0.000033773333,0.00040251244,0.00029603657,0.0002466863,0.00010052223],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044457166,0.00013315164,0.00038604965,0.00007996768,0.00008286731,0.0000070130245,0.00011235635,0.00006219669,0.000018669802],"category_scores_gemma":[0.00020178917,0.0000874782,0.00036793627,0.00016454858,0.00006530387,0.000007158462,0.00002646498,0.0001549163,0.0000018113752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094157935,0.000080592436,0.000011960475,0.000014938255,0.00028561297,0.000013485911,0.000075060685,0.00038425584,0.99612147,0.00027317263,0.00029082378,0.0023544664],"study_design_scores_gemma":[0.0005893409,0.0031861307,0.00015524999,0.00020458654,0.00013471488,0.00010371631,0.00018719058,0.000003537465,0.99291176,0.00012646012,0.0022977071,0.00009960753],"about_ca_topic_score_codex":0.000040487834,"about_ca_topic_score_gemma":0.0000014128489,"teacher_disagreement_score":0.0032097148,"about_ca_system_score_codex":0.000013006349,"about_ca_system_score_gemma":0.00006751066,"threshold_uncertainty_score":0.35672575},"labels":[],"label_agreement":null},{"id":"W2038758551","doi":"10.1111/j.1440-1681.2009.05193.x","title":"p38 MITOGEN‐ACTIVATED PROTEIN KINASE (MAPK) IS ACTIVATED BY NORADRENALINE AND SERVES A CARDIOPROTECTIVE ROLE, WHEREAS ADRENALINE INDUCES p38 MAPK DEPHOSPHORYLATION","year":2009,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Dephosphorylation; MAPK/ERK pathway; p38 mitogen-activated protein kinases; Protein kinase A; Kinase; Programmed cell death; Mitogen-activated protein kinase; Apoptosis; Chemistry; Cell biology; Phosphorylation; Fragmentation (computing); Molecular biology; Biology; Biochemistry; Phosphatase","score_opus":0.01238781286727789,"score_gpt":0.3063453918247989,"score_spread":0.293957578957521,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038758551","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98941666,0.009418153,0.000041537012,0.0002849331,0.00021837941,0.0005127425,0.000052020077,0.000023877017,0.00003171144],"genre_scores_gemma":[0.9970352,0.00056501146,0.00012997654,0.0014480314,0.00040107354,0.00007025628,0.00019351332,0.000019923109,0.00013700021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980621,0.00033682593,0.0004241847,0.0007725832,0.000075609656,0.00032872538],"domain_scores_gemma":[0.99936163,0.000041531002,0.00017657808,0.000131423,0.000060299542,0.00022854788],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002079773,0.0003296422,0.0004837418,0.00003647028,0.00022889632,0.000022164404,0.000104135,0.0005014688,0.00016106332],"category_scores_gemma":[0.000022470076,0.0002850947,0.00010229266,0.0000793577,0.0003580806,0.000023679537,0.00013012512,0.0003296819,0.0000024628541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024203486,0.000308614,0.00010738925,0.000014057661,0.00023916602,0.0000038283183,0.00015556706,0.0000035860467,0.99202996,0.000020342195,0.00078728807,0.0039098593],"study_design_scores_gemma":[0.0028332053,0.0022150085,0.0015156976,0.0000183135,0.000052544376,0.00001871729,0.00018747727,0.00009287928,0.98996437,0.0005545203,0.0022154048,0.00033188792],"about_ca_topic_score_codex":0.00008045988,"about_ca_topic_score_gemma":0.0000017982629,"teacher_disagreement_score":0.008853142,"about_ca_system_score_codex":0.000009242027,"about_ca_system_score_gemma":0.000029141242,"threshold_uncertainty_score":0.9999601},"labels":[],"label_agreement":null},{"id":"W2039009797","doi":"10.1007/s00418-010-0707-9","title":"Striatal interneurons in dissociated cell culture","year":2010,"lang":"en","type":"article","venue":"Histochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Calretinin; Interneuron; Ganglionic eminence; Cholinergic; Parvalbumin; Striatum; Biology; Neuroscience; Cholinergic neuron; Medium spiny neuron; Calbindin; GABAergic; Dopamine; Inhibitory postsynaptic potential; Immunohistochemistry; Immunology","score_opus":0.003452155017546521,"score_gpt":0.2091701977408014,"score_spread":0.20571804272325486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039009797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98944485,0.00048473763,0.00011091178,0.00002303298,0.00024805902,0.00007619205,0.000028776436,0.0000109673665,0.009572496],"genre_scores_gemma":[0.99597454,0.00013396725,0.0002677022,0.000079899,0.0001890294,0.000013836596,0.00029796132,0.00001308677,0.003029969],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991394,0.000027911463,0.00017524701,0.00038765467,0.000034661392,0.00023509632],"domain_scores_gemma":[0.99961567,0.000008174805,0.00007288408,0.00019174803,0.000024528243,0.00008699694],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000097986594,0.00015987181,0.00014670186,0.000018544019,0.00005667499,0.0000115828925,0.00015659498,0.00040945713,0.00018216691],"category_scores_gemma":[0.000031802367,0.00014895001,0.000058103877,0.000041639734,0.000092586495,0.000002234082,0.00009329874,0.0003052988,0.0000051916163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034578006,0.000055035518,0.0012192864,0.000016779932,0.0000040819596,0.0000018436089,0.000053642078,0.0000010718816,0.9978232,0.00004235375,0.00047390704,0.00027424959],"study_design_scores_gemma":[0.0005292206,0.00011652961,0.00007238893,0.0000034823868,0.000006362625,0.00000503881,0.00008263548,0.000014210221,0.9580171,0.00008955953,0.040883828,0.00017962017],"about_ca_topic_score_codex":0.000018953973,"about_ca_topic_score_gemma":0.000021750948,"teacher_disagreement_score":0.040409923,"about_ca_system_score_codex":0.000008213751,"about_ca_system_score_gemma":0.000032832068,"threshold_uncertainty_score":0.60740054},"labels":[],"label_agreement":null},{"id":"W2039087375","doi":"10.1074/jbc.m411456200","title":"G Protein-coupled Receptor Endocytosis in ADP-ribosylation Factor 6-depleted Cells","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"McGill University","keywords":"Internalization; Endocytosis; Cell biology; Endocytic cycle; Receptor; G protein-coupled receptor; Biology; Caveolae; Pinocytosis; Chemistry; Signal transduction; Biochemistry","score_opus":0.017801710570395025,"score_gpt":0.2365757180625,"score_spread":0.21877400749210496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039087375","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99746263,0.0003668634,0.0017082507,0.00010777956,0.0001074852,0.00012470277,0.000012863475,0.000007837721,0.00010157453],"genre_scores_gemma":[0.9965749,0.00019066696,0.0026527254,0.00006668384,0.0004150609,0.0000076369515,0.000029246201,0.00001432538,0.0000487856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876887,0.000039819854,0.0005225775,0.0002421462,0.0001730183,0.0002535448],"domain_scores_gemma":[0.9992381,0.000014663686,0.00034511182,0.00014533795,0.00013030884,0.00012652541],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020849779,0.00018439021,0.0002809466,0.000031807864,0.000037812508,0.000023397928,0.00023582688,0.0003547091,0.00035421446],"category_scores_gemma":[0.00020142239,0.00013691788,0.00019873284,0.00010870463,0.0000452795,0.0000076081215,0.000054593154,0.00027050494,0.000006352166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019881927,0.00011442439,0.0004237965,0.000016027634,0.000026069312,0.000011427376,0.000017110051,0.00014131542,0.9986144,0.0000059374315,0.000023280603,0.00040739286],"study_design_scores_gemma":[0.0011337879,0.0004028029,0.00020829788,0.00005709591,0.0000050538774,0.000025995188,0.000073804345,0.000009692278,0.9964113,0.00022950544,0.0012665541,0.00017609804],"about_ca_topic_score_codex":0.0000059835434,"about_ca_topic_score_gemma":0.0000012416909,"teacher_disagreement_score":0.002203087,"about_ca_system_score_codex":0.00007059744,"about_ca_system_score_gemma":0.00009801402,"threshold_uncertainty_score":0.5583349},"labels":[],"label_agreement":null},{"id":"W2039103666","doi":"10.1038/sj.tpj.6500416","title":"Analysis of a missense variant of the human N-formyl peptide receptor that is associated with agonist-independent β-arrestin association and indices of inflammation","year":2006,"lang":"en","type":"article","venue":"The Pharmacogenomics Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Missense mutation; Agonist; Arrestin; Receptor; Peptide; B2 receptor; Inflammation; Association (psychology); Medicine; Pharmacology; Chemistry; Internal medicine; Endocrinology; G protein-coupled receptor; Mutation; Biochemistry; Psychology; Gene","score_opus":0.011055536814678506,"score_gpt":0.23759589799221723,"score_spread":0.22654036117753873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039103666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99898225,0.00023830372,0.00031891585,0.00012175392,0.000057605812,0.00011254526,0.00007988765,0.0000014512683,0.00008730888],"genre_scores_gemma":[0.9994713,0.00014870244,0.00008377945,0.000027575023,0.0000908558,0.0000016457403,0.000034527773,0.000010501578,0.0001311117],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989367,0.0001604812,0.0003909083,0.00010637078,0.00027556787,0.0001299721],"domain_scores_gemma":[0.9982253,0.000040122042,0.0013889436,0.00012136917,0.00019353973,0.000030724084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010573769,0.00010421955,0.00021850558,0.000077062505,0.00016080664,0.00002510891,0.00018550936,0.00007690412,0.00006526544],"category_scores_gemma":[0.00003630888,0.000064342385,0.00015137446,0.00017228967,0.000051497052,0.000007652905,0.00005000155,0.00013459662,1.1115189e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000686852,0.00003631264,0.017812204,0.0000070038573,0.001403981,0.0000010177737,0.00033577878,0.0021871694,0.97781837,0.000029184825,0.00008971102,0.00021058894],"study_design_scores_gemma":[0.000673574,0.000082119055,0.013653097,0.000027033208,0.0012654107,0.000019111465,0.00016202657,0.00091143243,0.9828223,0.00013884589,0.00015766153,0.000087395034],"about_ca_topic_score_codex":0.0000934231,"about_ca_topic_score_gemma":0.00008590123,"teacher_disagreement_score":0.005003929,"about_ca_system_score_codex":0.00005184841,"about_ca_system_score_gemma":0.00006678713,"threshold_uncertainty_score":0.26238063},"labels":[],"label_agreement":null},{"id":"W2039482493","doi":"10.1073/pnas.0604049104","title":"D1–D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of G <sub>q</sub> /11 in the striatum","year":2006,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":489,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"Dopamine receptor D2; Agonist; Dopamine receptor D1; Dopamine; Dopamine receptor; Chemistry; Partial agonist; Endogenous agonist; D2-like receptor; Receptor; Nucleus accumbens; Dopamine receptor D3; G protein-coupled receptor; Striatum; Pharmacology; Cell biology; Biology; Neuroscience; Biochemistry","score_opus":0.01677328373674317,"score_gpt":0.2644418380162363,"score_spread":0.2476685542794931,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039482493","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99779487,0.000035791974,0.00002525316,0.0016902239,0.000019525005,0.0002610613,0.000009186048,0.0000021074495,0.0001620068],"genre_scores_gemma":[0.99898136,0.000025896667,0.00056662725,0.00028400766,0.00010311161,0.000021295067,0.0000014843637,0.0000042188844,0.000011991468],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989175,0.000016486065,0.0002612554,0.00020039611,0.00047526768,0.00012905043],"domain_scores_gemma":[0.9993101,0.000038426224,0.00040126446,0.000010217209,0.00022253719,0.000017458398],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00095719105,0.00008774643,0.00012849737,0.000109672554,0.000072206836,0.000009634508,0.00044883808,0.00008519715,0.000006645244],"category_scores_gemma":[0.0000996741,0.000052089967,0.00004433161,0.00041497257,0.00021928722,0.000021776441,0.000055823224,0.00008739253,1.5154097e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062569,0.00004516698,0.0016298593,0.00002029634,0.000008679941,3.250644e-9,0.00003867725,0.00069131365,0.99561125,0.0014121283,0.00038490415,0.00009512644],"study_design_scores_gemma":[0.00028439244,0.00018945774,0.0059771403,0.000045612785,0.0000065465842,0.0000017084078,0.0002756028,0.00019230523,0.9921654,0.0006123852,0.00018570447,0.000063732135],"about_ca_topic_score_codex":0.000014350821,"about_ca_topic_score_gemma":0.0000010348979,"teacher_disagreement_score":0.004347281,"about_ca_system_score_codex":0.000016113287,"about_ca_system_score_gemma":0.00003427073,"threshold_uncertainty_score":0.21241671},"labels":[],"label_agreement":null},{"id":"W2039820148","doi":"10.1371/journal.pone.0063612","title":"Early versus Late-Phase Consolidation of Opiate Reward Memories Requires Distinct Molecular and Temporal Mechanisms in the Amygdala-Prefrontal Cortical Pathway","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Neuroscience; Memory consolidation; Opiate; Basolateral amygdala; Amygdala; Prefrontal cortex; Psychology; Medicine; Hippocampus; Internal medicine; Cognition; Receptor","score_opus":0.02594802506397164,"score_gpt":0.24214342714716505,"score_spread":0.2161954020831934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039820148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976201,0.00016369333,0.0015746314,0.00008790082,0.000048098194,0.0003311759,0.000021026639,0.0000076096244,0.00014575642],"genre_scores_gemma":[0.99750805,0.000025294292,0.0021868835,0.00004150187,0.00003945527,0.000048693604,0.000099178666,0.000014747707,0.000036224334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900883,0.00011835199,0.00025173675,0.00023074988,0.00020924678,0.00018110152],"domain_scores_gemma":[0.9995399,0.00002935532,0.00009086512,0.00021425151,0.00007147878,0.000054144544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002106956,0.000126743,0.00018519137,0.000027962898,0.00005306035,0.000040540046,0.0001324305,0.00010909327,0.00006411474],"category_scores_gemma":[0.00012301198,0.00009848967,0.000041104384,0.000053101976,0.00008722183,0.000012304656,0.00007150852,0.00009695912,0.000004549968],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022194558,0.00027203272,0.00030937177,0.000025411468,0.00006685263,0.000005695514,0.00020620102,0.0000015183697,0.99763894,0.0009975196,0.0000062861836,0.00024823126],"study_design_scores_gemma":[0.001373249,0.0013211916,0.0008087267,0.00003907895,0.000041779047,0.0000016697007,0.00026709307,0.00027684844,0.99441904,0.0013019699,0.000013347984,0.00013601828],"about_ca_topic_score_codex":0.00011407938,"about_ca_topic_score_gemma":0.000022497135,"teacher_disagreement_score":0.0032199065,"about_ca_system_score_codex":0.0000075874023,"about_ca_system_score_gemma":0.000028237417,"threshold_uncertainty_score":0.4016292},"labels":[],"label_agreement":null},{"id":"W2039843941","doi":"10.1016/s0006-2952(99)00364-0","title":"Effect of the β-adrenoceptor agonist flerobuterol on serotonin synthesis in the rat brain","year":2000,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Agonist; Internal medicine; Endocrinology; Serotonin; Chemistry; Superior colliculus; Dorsal raphe nucleus; Tryptophan; Serotonin Agonist; Postsynaptic potential; Hypothalamus; 5-HT receptor; Receptor; Biology; Serotonergic; Medicine; Amino acid; Neuroscience; Biochemistry","score_opus":0.005766418970181316,"score_gpt":0.26447703129064803,"score_spread":0.2587106123204667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039843941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969522,0.00028646426,0.00000970929,0.0014991525,0.00026122344,0.0005018107,0.0000145687445,0.000006877583,0.00046803246],"genre_scores_gemma":[0.996391,0.000052539184,0.000027415303,0.002802044,0.00027259253,0.0001717593,0.000014851096,0.000018195726,0.0002495897],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838287,0.00061964575,0.00023867156,0.00032584506,0.00015041346,0.00028257442],"domain_scores_gemma":[0.99933916,0.00024283152,0.00006746046,0.00028726162,0.00001699164,0.00004628427],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00053853926,0.00019383075,0.00021171739,0.000023359125,0.00007602126,0.000011443494,0.00056706544,0.00021108669,0.0018178383],"category_scores_gemma":[0.00009131661,0.000110900226,0.0001732284,0.00012815242,0.00015736012,0.0000019651598,0.00006437559,0.00020745593,0.000022758617],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051654084,0.00008233817,0.000060115057,0.00001987259,0.0000264968,0.0000018905944,0.000028582368,0.000050470677,0.92725164,0.000008972996,0.07020977,0.0017432991],"study_design_scores_gemma":[0.00068776676,0.00048414292,0.00006187603,0.000016374952,0.000031421005,0.000009203558,0.000007996409,0.00004424489,0.9770021,0.0000097045095,0.021530287,0.00011489484],"about_ca_topic_score_codex":0.0000100316265,"about_ca_topic_score_gemma":6.889117e-7,"teacher_disagreement_score":0.049750436,"about_ca_system_score_codex":0.000018230752,"about_ca_system_score_gemma":0.000030277775,"threshold_uncertainty_score":0.99909467},"labels":[],"label_agreement":null},{"id":"W2039865353","doi":"10.1210/me.2001-0220","title":"Dopamine-D2S Receptor Inhibition of Calcium Influx, Adenylyl Cyclase, and Mitogen-Activated Protein Kinase in Pituitary Cells: Distinct Gα and Gβγ Requirements","year":2002,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Biology; MAPK/ERK pathway; Protein kinase A; Gs alpha subunit; Adenylyl cyclase; Cell biology; Forskolin; G protein; Signal transduction; Phosphorylation; Receptor; Molecular biology; Biochemistry","score_opus":0.016614683188698867,"score_gpt":0.2358673199945413,"score_spread":0.21925263680584245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039865353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995855,0.0024353012,0.0008404986,0.000102181,0.00012525391,0.0004439667,0.000030448808,0.000015297483,0.00015208231],"genre_scores_gemma":[0.9984417,0.00022272885,0.00083804905,0.00009121964,0.000047516485,0.000074257594,0.00010717217,0.000033799643,0.00014358916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998368,0.00016162658,0.0003855192,0.000535473,0.00013541227,0.00041393176],"domain_scores_gemma":[0.99942064,0.000010936542,0.00013448906,0.00027125078,0.00006247052,0.00010020409],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008432896,0.0002517585,0.00028646045,0.00013938759,0.00005480734,0.000014835957,0.00009841123,0.0001915443,0.00010719712],"category_scores_gemma":[0.000075566684,0.0002624563,0.000056779096,0.00012510298,0.00015640557,0.000011576923,0.00018557582,0.0001593253,0.000004379435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097522534,0.000098126104,0.00067247957,0.000061556755,0.000041948293,0.000085861735,0.000054079814,0.00000973522,0.99628484,0.00011257773,0.00008932122,0.002391971],"study_design_scores_gemma":[0.001470025,0.0005031107,0.00031254854,0.000051012812,0.000016988137,0.000032497195,0.00006304314,0.000073221774,0.99484664,0.00008669417,0.0022915204,0.00025271048],"about_ca_topic_score_codex":0.000094712064,"about_ca_topic_score_gemma":0.000020315752,"teacher_disagreement_score":0.0025866975,"about_ca_system_score_codex":0.000021586618,"about_ca_system_score_gemma":0.000015728745,"threshold_uncertainty_score":0.9999828},"labels":[],"label_agreement":null},{"id":"W2040026853","doi":"10.1016/j.ejphar.2010.05.018","title":"Specific binding of photoaffinity-labeling peptidomimetics of Pro-Leu-Gly-NH2 to the dopamine D2L receptor: Evidence for the allosteric modulation of the dopamine receptor","year":2010,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Allosteric regulation; Chemistry; Dopamine; Photoaffinity labeling; Dopamine receptor; Dopamine receptor D2; Receptor; Pharmacology; Biophysics; Neuroscience; Biochemistry; Stereochemistry; Biology","score_opus":0.04409459694731991,"score_gpt":0.3034210480750368,"score_spread":0.25932645112771685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040026853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9873142,0.0008399493,0.0074888016,0.0009775641,0.0026847718,0.0006066142,0.000030710078,0.0000026404014,0.00005471805],"genre_scores_gemma":[0.990758,0.0005993372,0.0071171355,0.00014922822,0.0011662612,0.0000070859396,0.000005684055,0.00003991648,0.00015733001],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99776906,0.0005945671,0.0009248736,0.00020977549,0.00026779997,0.00023394772],"domain_scores_gemma":[0.99740475,0.00035817383,0.0012524921,0.00031617557,0.00060131087,0.00006708292],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0031771527,0.0001852585,0.0003173698,0.000088985515,0.00014378871,0.000016097762,0.000923792,0.00006256378,0.00027931243],"category_scores_gemma":[0.00049390044,0.00010471548,0.0002612816,0.00022899146,0.00017193636,0.000014444769,0.00022722597,0.000355163,0.0000041702738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069994916,0.00007811978,0.00012456016,0.000041952095,0.00013637394,8.4651714e-7,0.00025263982,0.0015429116,0.9900233,0.000022284297,0.002403652,0.0046734097],"study_design_scores_gemma":[0.0010106856,0.0010176378,0.0002240456,0.000094205505,0.0001155232,0.000025200097,0.00015946821,0.00035012836,0.96157724,0.000005459108,0.03531194,0.00010849848],"about_ca_topic_score_codex":0.0000021030892,"about_ca_topic_score_gemma":0.0000021059486,"teacher_disagreement_score":0.032908287,"about_ca_system_score_codex":0.000014839682,"about_ca_system_score_gemma":0.0000870262,"threshold_uncertainty_score":0.42701733},"labels":[],"label_agreement":null},{"id":"W2040175983","doi":"10.1136/jim-52-06-32","title":"Endogenous Glucose Production in Type 2 Diabetes: Basal and Postprandial. Role of Diurnal Rhythms","year":2004,"lang":"en","type":"review","venue":"Journal of Investigative Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Postprandial; Internal medicine; Endocrinology; Endogeny; Basal (medicine); Morning; Circadian rhythm; Type 2 diabetes; Diabetes mellitus; Glycemic; Chemistry; Medicine","score_opus":0.043847444988134636,"score_gpt":0.2833091723203734,"score_spread":0.23946172733223875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040175983","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.05540961,0.9437216,0.000012704454,0.00008389862,0.00048246805,0.00024050914,0.0000057387447,0.0000012121302,0.000042261785],"genre_scores_gemma":[0.017778935,0.9803641,0.0005907511,0.000040254254,0.0011479863,0.000004020166,0.000030592146,0.0000310018,0.00001239129],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814993,0.00021888535,0.00095371273,0.00022443336,0.00026724016,0.00018580681],"domain_scores_gemma":[0.9981933,0.000034826648,0.0011703816,0.00014056372,0.00030360848,0.00015732503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00089667673,0.00027475168,0.0012359135,0.0002523611,0.000030223786,0.0000060862876,0.0001441876,0.00021831627,0.000025470927],"category_scores_gemma":[0.0010003477,0.00018297319,0.00014983275,0.00024231743,0.00041112606,0.000008588852,0.000043874326,0.00040664244,5.532049e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016549218,0.000115680006,0.00006420001,0.005503147,0.0005204238,0.00005607015,0.00081263843,0.000033814278,0.75610125,0.000086335276,0.00008423399,0.2364567],"study_design_scores_gemma":[0.0034052532,0.01592346,0.00006405704,0.09227824,0.0014995574,0.0015284205,0.000793718,0.000005199953,0.686231,0.006068474,0.19135326,0.00084930996],"about_ca_topic_score_codex":0.000012950658,"about_ca_topic_score_gemma":0.000003837482,"teacher_disagreement_score":0.2356074,"about_ca_system_score_codex":0.00005556951,"about_ca_system_score_gemma":0.0005400671,"threshold_uncertainty_score":0.746143},"labels":[],"label_agreement":null},{"id":"W2040826145","doi":"10.1210/en.2003-0677","title":"The Constitutively Active N111G-AT1 Receptor for Angiotensin II Maintains a High Affinity Conformation Despite Being Uncoupled from Its Cognate G Protein Gq/11α","year":2003,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Angiotensin II receptor type 1; Receptor; Agonist; Angiotensin II; Chemistry; Mutant; Enzyme-linked receptor; G protein-coupled receptor; Biochemistry; Biophysics; Internal medicine; Molecular biology; Biology; Endocrinology; Medicine","score_opus":0.01092953101265956,"score_gpt":0.231820903875845,"score_spread":0.22089137286318544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040826145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9761604,0.0004049406,0.020254696,0.00042368026,0.00063737785,0.0011544654,0.00020611897,0.000038388167,0.0007199472],"genre_scores_gemma":[0.9936392,0.0001787284,0.0046858666,0.00026483324,0.0001822568,0.0002282655,0.0003154007,0.000026787706,0.00047868938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983645,0.0001849124,0.0003352039,0.00041086154,0.0001145001,0.0005899992],"domain_scores_gemma":[0.999037,0.00010805515,0.00021962177,0.00026530208,0.00028458552,0.00008538621],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022215185,0.00025130706,0.00025755027,0.0000482816,0.0006948273,0.000033592067,0.000210035,0.00020667231,0.000106098654],"category_scores_gemma":[0.00063299923,0.00020657109,0.00013311578,0.00008135305,0.00016874298,0.00001538624,0.00010555207,0.00018748706,0.000023058954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004247749,0.000041000654,0.000018905925,0.000006555498,0.00018831946,0.0000048892907,0.00015917719,0.000050285347,0.9313989,0.0642909,0.00042748926,0.002988795],"study_design_scores_gemma":[0.001426995,0.00046019422,0.000059343405,0.00001696311,0.00003080928,0.000015632822,0.00031917202,0.00011202212,0.87803227,0.0033337828,0.115952015,0.00024082972],"about_ca_topic_score_codex":0.000059310092,"about_ca_topic_score_gemma":0.00007510397,"teacher_disagreement_score":0.11552452,"about_ca_system_score_codex":0.000052449137,"about_ca_system_score_gemma":0.00018646535,"threshold_uncertainty_score":0.8423725},"labels":[],"label_agreement":null},{"id":"W2040896718","doi":"10.1074/jbc.m205035200","title":"G Protein-coupled Receptors Form Stable Complexes with Inwardly Rectifying Potassium Channels and Adenylyl Cyclase","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":202,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Adenylyl cyclase; Immunoprecipitation; Receptor; G protein; G protein-coupled receptor; Cell biology; Effector; Signal transduction; HEK 293 cells; Chemistry; Biophysics; Biology; Gs alpha subunit; Biochemistry; Gene","score_opus":0.023962438762181175,"score_gpt":0.22703881667146233,"score_spread":0.20307637790928115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040896718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966421,0.001588733,0.0009183201,0.00015742048,0.00009508276,0.00012424751,0.0000062288973,0.000010517119,0.0004573512],"genre_scores_gemma":[0.9959226,0.00044899815,0.0023596692,0.00007746814,0.00050959084,0.000009263863,0.000013998452,0.000018274024,0.0006401113],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880356,0.000037262293,0.00038832304,0.00027919025,0.00018165106,0.00030999075],"domain_scores_gemma":[0.9991324,0.00002159613,0.00034793967,0.00014600492,0.00014895918,0.00020311994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030989645,0.00022507521,0.00033143314,0.000025301504,0.00012503078,0.000061262486,0.00019428709,0.00028290568,0.0005310262],"category_scores_gemma":[0.0001367833,0.00014656415,0.00011351339,0.000087352164,0.000115750765,0.000011210517,0.00008138683,0.00029350762,0.0000017745577],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020682522,0.00007767353,0.0004756244,0.000038465405,0.000066050205,0.000020514959,0.00003484984,0.000023718276,0.99778813,0.0000047140843,0.0003907162,0.00087273214],"study_design_scores_gemma":[0.0008114246,0.00090383587,0.000049530656,0.00008781437,0.000018950892,0.00037866467,0.00023799684,0.00014447754,0.9890098,0.000103180384,0.008005925,0.0002483781],"about_ca_topic_score_codex":0.0000037665177,"about_ca_topic_score_gemma":6.539487e-7,"teacher_disagreement_score":0.008778295,"about_ca_system_score_codex":0.000025751247,"about_ca_system_score_gemma":0.000027196662,"threshold_uncertainty_score":0.5976713},"labels":[],"label_agreement":null},{"id":"W2040933491","doi":"10.1016/j.bpj.2012.11.180","title":"Differences in the Allosteric Interaction between Agonists and GMP-PNP in Monomers and Oligomers of the M2 Muscarinic Cholinergic Receptor Fused to GαI1","year":2013,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Allosteric regulation; Oxotremorine; Chemistry; Oligomer; Monomer; Agonist; Biochemistry; Receptor; Biophysics; Diacylglycerol kinase; Stereochemistry; Biology; Signal transduction; Protein kinase C","score_opus":0.016445285690364016,"score_gpt":0.24573143258156965,"score_spread":0.22928614689120563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040933491","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990771,0.00004699785,0.00003452315,0.0005506083,0.000115843046,0.00013905238,0.0000024108472,9.4340646e-7,0.000032531494],"genre_scores_gemma":[0.9994165,0.00014087875,0.00008419618,0.00012822496,0.00019475509,0.000009566376,0.0000023679938,0.0000062955583,0.000017226232],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992723,0.00011742694,0.0002142648,0.00014893795,0.00010371897,0.0001433827],"domain_scores_gemma":[0.9996914,0.000027830465,0.000093632094,0.00010075363,0.000024095845,0.00006227546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014718568,0.00009905687,0.00015156022,0.00004418001,0.000049292536,0.00005749433,0.00016694218,0.00006208096,0.000015245104],"category_scores_gemma":[0.000024163946,0.000056489764,0.000052606854,0.00010963456,0.000054258744,0.00001066138,0.00007657794,0.00017365221,0.0000016709597],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023130624,0.00003056348,0.014087539,0.0000055206865,0.000015082123,3.3627003e-7,0.0003406057,0.000006114394,0.9784281,0.000011497773,0.00003045678,0.007021025],"study_design_scores_gemma":[0.00090907124,0.0006620816,0.7556735,0.00010089948,0.000022554683,0.00002050337,0.0018686312,0.00019472218,0.2395341,0.00016222271,0.00059929397,0.0002524029],"about_ca_topic_score_codex":0.00007903504,"about_ca_topic_score_gemma":0.000011743716,"teacher_disagreement_score":0.74158597,"about_ca_system_score_codex":0.000010977345,"about_ca_system_score_gemma":0.000015037526,"threshold_uncertainty_score":0.23035857},"labels":[],"label_agreement":null},{"id":"W2041007654","doi":"10.1139/o06-207","title":"The ASP receptor C5L2 is regulated by metabolic hormones associated with insulin resistance","year":2007,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University; Université Laval; McGill University Health Centre","funders":"Canada Research Chairs","keywords":"Internal medicine; Endocrinology; Adipocyte; Receptor; Insulin resistance; Insulin; Chemistry; Adipose tissue; Biology; Medicine","score_opus":0.004144485058539492,"score_gpt":0.19965430113387578,"score_spread":0.1955098160753363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041007654","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9640304,0.032881226,0.00035033928,0.00019899053,0.00010231559,0.00012517867,0.00007926255,0.00002277459,0.002209504],"genre_scores_gemma":[0.98698723,0.00289805,0.0002489424,0.00022410083,0.00015974714,0.000013142776,0.00044836698,0.000024888943,0.0089954985],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861455,0.00006179584,0.00027851702,0.0005043706,0.00009588194,0.00044487114],"domain_scores_gemma":[0.9991933,0.000055592303,0.00018613055,0.00032500734,0.00011168358,0.00012830207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005264651,0.00024757886,0.00020645717,0.000014887365,0.00030866152,0.000034628345,0.00022990904,0.0004565033,0.00004482693],"category_scores_gemma":[0.00007879992,0.00017022369,0.000064752385,0.00013287875,0.0002625013,0.0000030758356,0.00007406695,0.00015252354,0.0000036521508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029289737,0.000039650236,0.00017462879,0.000008003822,0.000081947896,0.0000010179793,0.000024079181,1.9978395e-7,0.9909615,0.00006217406,0.006313486,0.002040428],"study_design_scores_gemma":[0.00046863736,0.00012757085,0.00007615109,0.000009692393,0.000019912228,0.0000024937337,0.00010578943,0.000002126298,0.79307604,0.000058761434,0.20584215,0.0002106949],"about_ca_topic_score_codex":0.000008528471,"about_ca_topic_score_gemma":0.000011805054,"teacher_disagreement_score":0.19952868,"about_ca_system_score_codex":0.0000120817285,"about_ca_system_score_gemma":0.00005043492,"threshold_uncertainty_score":0.6941521},"labels":[],"label_agreement":null},{"id":"W2041337283","doi":"10.1021/jm2015099","title":"From the First Selective Non-Peptide AT<sub>2</sub>Receptor Agonist to Structurally Related Antagonists","year":2012,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Agonist; Chemistry; Receptor; Antagonist; Stereochemistry; Chemical synthesis; Competitive antagonist; Structure–activity relationship; In vitro; Biochemistry","score_opus":0.004845431412579254,"score_gpt":0.22149417537961008,"score_spread":0.21664874396703082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041337283","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99602485,0.0012565985,0.0003059949,0.0010955393,0.00077103416,0.000108941946,0.00002898814,0.0000061048336,0.0004019266],"genre_scores_gemma":[0.9946254,0.00015878062,0.00053022424,0.0006067067,0.0037848454,0.0000047520584,0.00006178764,0.00003544497,0.00019208973],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982716,0.000041518866,0.0005562959,0.00024032376,0.00046750295,0.00042277604],"domain_scores_gemma":[0.9985672,0.00006237601,0.0004631168,0.0002752571,0.000240119,0.00039193532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005515042,0.0002643212,0.0003212355,0.000020925396,0.0002411735,0.000032676428,0.0004359704,0.00024595307,0.0002547648],"category_scores_gemma":[0.00025010586,0.00018169056,0.00021840406,0.0001300827,0.000093102084,0.000013616124,0.00013968349,0.00044568596,0.00002299024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031834928,0.000036598136,0.0015853443,0.000017558661,0.00018915968,0.000010648775,0.00055753277,0.000031201314,0.9672497,0.0000012603773,0.02925215,0.00075052155],"study_design_scores_gemma":[0.0007305068,0.00022713216,0.0018036009,0.00012087666,0.00008546051,0.00035679768,0.0004964829,0.000006952896,0.96974015,0.00003338046,0.026180603,0.00021806535],"about_ca_topic_score_codex":0.000016535065,"about_ca_topic_score_gemma":0.0000064793917,"teacher_disagreement_score":0.003071547,"about_ca_system_score_codex":0.00013991274,"about_ca_system_score_gemma":0.00015471582,"threshold_uncertainty_score":0.74091256},"labels":[],"label_agreement":null},{"id":"W2041485880","doi":"10.1016/s0898-6568(02)00121-3","title":"The N-terminal non-RGS domain of human regulator of G-protein signalling 1 contributes to its ability to inhibit pheromone receptor signalling in yeast","year":2003,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Biology; GTPase-activating protein; RGS2; G protein; Cell biology; Mutant; Regulator of G protein signaling; Gene; Signal transduction; Genetics","score_opus":0.0104016494852586,"score_gpt":0.23354028156084633,"score_spread":0.22313863207558773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041485880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9297664,0.0015372413,0.06726542,0.00005299779,0.00014025641,0.0010761465,0.000021715225,0.000015143011,0.0001246804],"genre_scores_gemma":[0.993618,0.000021562591,0.0058011827,0.000048870053,0.00014563662,0.0000936684,0.000036062615,0.00006949154,0.00016553109],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99652004,0.00034233156,0.0012309296,0.0007719256,0.00044567132,0.000689121],"domain_scores_gemma":[0.998396,0.00008720006,0.00038743814,0.00048440005,0.00040249087,0.00024247613],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0026830302,0.00040882285,0.00063214765,0.00017040143,0.00026493543,0.00006316912,0.0005607847,0.00030786594,0.00008906851],"category_scores_gemma":[0.0003045512,0.00037290176,0.0002725358,0.0005141608,0.00010928905,0.000014032442,0.00015356376,0.00026643596,0.000012252487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021594293,0.00012899384,0.00014007409,0.000112312715,0.000060669165,0.0000081890985,0.0003362473,0.0045486763,0.9928499,0.0012799087,0.00002327996,0.0002957907],"study_design_scores_gemma":[0.0007774301,0.00057055557,0.000016925627,0.00046818473,0.000023641449,0.0000020686912,0.00051638496,0.00026627473,0.99554074,0.000787184,0.0006366197,0.000393964],"about_ca_topic_score_codex":0.00003727202,"about_ca_topic_score_gemma":0.000038473292,"teacher_disagreement_score":0.063851595,"about_ca_system_score_codex":0.00007548752,"about_ca_system_score_gemma":0.00015271112,"threshold_uncertainty_score":0.99987227},"labels":[],"label_agreement":null},{"id":"W2041696685","doi":"10.3821/1913-701x(2007)140[410:atotg]2.0.co;2","title":"A tale of two glitazones","year":2007,"lang":"en","type":"article","venue":"Canadian Pharmacists Journal / Revue des Pharmaciens du Canada","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine","score_opus":0.01705682306989073,"score_gpt":0.27007080555698104,"score_spread":0.2530139824870903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041696685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930568,0.00141399,0.0024454633,0.000016399697,0.0014163626,0.00013662122,0.00013979751,0.000005138713,0.0013694539],"genre_scores_gemma":[0.9959961,0.0009849072,0.00074370747,0.00064410036,0.0010469147,0.0000026864723,0.00003318096,0.000038513164,0.0005098895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981993,0.00006117814,0.0004815932,0.00027243135,0.0002585172,0.0007269836],"domain_scores_gemma":[0.9979377,0.000022204087,0.00020862311,0.00019132932,0.00040681864,0.0012333312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079436594,0.00022918063,0.00023073841,0.00018235747,0.00032500687,0.00004530352,0.00041522895,0.00006302202,0.0005804037],"category_scores_gemma":[0.00008750025,0.0002413314,0.00014762473,0.00025129522,0.00011546918,0.00001560113,0.00003702052,0.00024427992,0.0000028387055],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000102711136,0.000025837315,0.00096680684,0.000056740104,0.0001385602,0.0070089423,0.00022268874,0.00060298236,0.9511712,0.000099607474,0.0051937685,0.03441015],"study_design_scores_gemma":[0.0015172674,0.00009720477,0.000012200423,0.00001308357,0.00005727205,0.1307245,0.00002200512,0.00025628513,0.80958396,0.00010213725,0.057180975,0.00043310388],"about_ca_topic_score_codex":0.01331185,"about_ca_topic_score_gemma":0.0982785,"teacher_disagreement_score":0.14158724,"about_ca_system_score_codex":0.00033253903,"about_ca_system_score_gemma":0.0017471382,"threshold_uncertainty_score":0.9932586},"labels":[],"label_agreement":null},{"id":"W2041926119","doi":"10.1139/cjpp-78-3-187","title":"Heterotrimeric G proteins in heart disease","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Heterotrimeric G protein; G protein; G protein-coupled receptor; Biology; G beta-gamma complex; GTPase-activating protein; GTP-binding protein regulators; Cell biology; G protein-coupled receptor kinase; Signal transduction","score_opus":0.008346955708737213,"score_gpt":0.24917491290267527,"score_spread":0.24082795719393804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041926119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99702907,0.0019906992,0.000015196517,0.0005521279,0.00024443457,0.00009264473,0.0000067311703,8.437156e-7,0.000068252695],"genre_scores_gemma":[0.9975368,0.0001716953,0.00012360586,0.0016980811,0.00031549833,0.000006081299,0.000006221563,0.000007730864,0.00013429394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993159,0.00012593169,0.00017650065,0.00013064088,0.000024428093,0.0002265865],"domain_scores_gemma":[0.9995111,0.000008208088,0.000048464593,0.000055651974,0.00003135992,0.00034517483],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00012465284,0.000085714964,0.00015360511,0.000084421954,0.000059260823,0.000004625125,0.00009723545,0.00008491849,0.0038639673],"category_scores_gemma":[0.000008823434,0.00007945358,0.000048871796,0.000052628537,0.000103151564,0.000004966217,0.0000065546606,0.00014258536,0.000006149218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017362175,0.000015859316,0.001058763,0.000010835508,0.000019627461,0.000032256565,0.000033645243,0.00026003257,0.9958904,0.0000142751005,0.0015961666,0.0008945422],"study_design_scores_gemma":[0.0017427172,0.0010138985,0.016535645,0.000022057937,0.00003992111,0.00015834688,0.00002410365,0.00006924686,0.8424884,0.0017068128,0.13593024,0.00026859596],"about_ca_topic_score_codex":0.0001798104,"about_ca_topic_score_gemma":0.00019659263,"teacher_disagreement_score":0.15340196,"about_ca_system_score_codex":0.00001091366,"about_ca_system_score_gemma":0.00034006688,"threshold_uncertainty_score":0.99704665},"labels":[],"label_agreement":null},{"id":"W2041972548","doi":"10.1155/2009/959168","title":"Determinants Present in the Receptor Carboxy Tail Are Responsible for Differences in Subtype-Specific Coupling of<mml:math xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"><mml:mi>β</mml:mi></mml:math>-Adrenergic Receptors to Phosphoinositide 3-Kinase","year":2009,"lang":"lv","type":"article","venue":"International Journal of Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Algorithm; Artificial intelligence; Computer science","score_opus":0.01899853281095093,"score_gpt":0.25732530183622404,"score_spread":0.2383267690252731,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041972548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99518377,0.0022567892,0.0003490865,0.00040165667,0.0015745744,0.00007266017,0.00005739786,0.0000030222707,0.000101065736],"genre_scores_gemma":[0.99553573,0.0024461828,0.00097270607,0.00023198679,0.000661286,0.000026441947,0.000058468715,0.000025017667,0.00004217768],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980556,0.000112195674,0.0008153804,0.00034185493,0.00032136287,0.00035362368],"domain_scores_gemma":[0.9983825,0.00025562197,0.000831887,0.00023247958,0.0001992339,0.00009826667],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00092175644,0.00021412372,0.000258059,0.00018890812,0.00008208042,0.00007544165,0.00075335795,0.0003984279,0.000057802084],"category_scores_gemma":[0.00023396617,0.000199981,0.00029948368,0.00012962654,0.00010476558,0.000024954146,0.00013166913,0.000293988,0.000013806883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027259442,0.00029396047,0.000689931,0.000052892094,0.00011336907,0.00012854359,0.0007219079,0.0015434048,0.8536562,0.13732383,0.0003735551,0.0023764726],"study_design_scores_gemma":[0.00093549397,0.0020501204,0.00041588888,0.00042939294,0.000037786805,0.000077455225,0.0010455938,0.020062665,0.96978885,0.00040562035,0.004519945,0.00023120259],"about_ca_topic_score_codex":0.00007549012,"about_ca_topic_score_gemma":0.00008474783,"teacher_disagreement_score":0.1369182,"about_ca_system_score_codex":0.000025611276,"about_ca_system_score_gemma":0.0002524626,"threshold_uncertainty_score":0.8154988},"labels":[],"label_agreement":null},{"id":"W2042550082","doi":"10.1006/mvre.2000.2263","title":"A New in Vitro Model for Agonist-Induced Communication between Microvascular Endothelial Cells","year":2000,"lang":"en","type":"article","venue":"Microvascular Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Medical Research Council","keywords":"Depolarization; Hyperpolarization (physics); Biophysics; Lucifer yellow; Membrane potential; Matrigel; Chemistry; Adenosine; Endothelial stem cell; Microcirculation; Monolayer; Biology; Gap junction; In vitro; Biochemistry; Internal medicine; Intracellular; Medicine","score_opus":0.05321043510076571,"score_gpt":0.33009084574514375,"score_spread":0.276880410644378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042550082","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9685289,0.0016638295,0.027824335,0.00017053878,0.000030299318,0.0014962375,0.000026529948,0.000017307571,0.00024197556],"genre_scores_gemma":[0.956569,0.0009781413,0.036133677,0.000095388925,0.00041875956,0.00027729737,0.0006455084,0.00010708472,0.0047751507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975998,0.00034665424,0.0003569312,0.0006129683,0.00037244,0.00071123143],"domain_scores_gemma":[0.99856806,0.00004667572,0.00003832561,0.0010136651,0.00016341198,0.00016984862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001990252,0.00021669736,0.00030142625,0.00015597422,0.00025854286,0.000108169814,0.0007258825,0.0003085233,0.00016042392],"category_scores_gemma":[0.00004645721,0.00022657249,0.0003779609,0.00022874233,0.00006256958,0.0000099277395,0.00016405401,0.00036495103,0.000058227248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019536955,0.000056128523,0.0000105264935,0.000024070756,0.000088254965,0.0000013779844,0.00013477371,0.00038639706,0.9491094,0.000018246283,0.0007313448,0.04924413],"study_design_scores_gemma":[0.0018172635,0.00012341989,0.0000071536656,0.000026362926,0.000016994658,0.000003140724,0.000040148578,0.0020252962,0.93928075,0.0004144924,0.056006797,0.00023817024],"about_ca_topic_score_codex":0.00055860134,"about_ca_topic_score_gemma":0.00006971787,"teacher_disagreement_score":0.05527545,"about_ca_system_score_codex":0.000070322865,"about_ca_system_score_gemma":0.00030031128,"threshold_uncertainty_score":0.92393583},"labels":[],"label_agreement":null},{"id":"W2042599603","doi":"10.1074/jbc.m309207200","title":"Structural Determinants Regulating Expression of the High Affinity Leukotriene B4 Receptor","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Leukotriene B4; Receptor; Cell biology; Chemistry; Expression (computer science); Biochemistry; Biology; Computer science; Immunology; Inflammation","score_opus":0.018012555154358408,"score_gpt":0.2446038473463257,"score_spread":0.2265912921919673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042599603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991873,0.00027186735,0.0001787596,0.000048262005,0.00021382808,0.000044957,0.000009339673,0.0000028770753,0.000042843065],"genre_scores_gemma":[0.996855,0.000057488287,0.0025878304,0.000032535565,0.00041138908,9.481693e-7,0.0000060975804,0.000007850762,0.000040814626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989761,0.000046263685,0.00046334902,0.0001619775,0.00018167998,0.0001705919],"domain_scores_gemma":[0.99896693,0.000019462894,0.0005917666,0.0001989249,0.00014502322,0.000077885976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025592837,0.000137372,0.00023811802,0.000009085629,0.00008763595,0.000011173378,0.00035905285,0.00026720695,0.00012661259],"category_scores_gemma":[0.0003599866,0.00007516242,0.00022107427,0.00006610614,0.000106162785,0.000005323903,0.00014842658,0.00020341673,4.0279235e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000119987046,0.000024754796,0.0018964509,0.000015741874,0.000010959477,0.0000015055882,0.000015487463,0.00027726157,0.9970748,0.0000061446635,0.000032173084,0.0005247798],"study_design_scores_gemma":[0.0005771963,0.0001969273,0.0020146251,0.00009947625,0.000008079526,0.00006672058,0.00006868216,0.0000029980736,0.9961763,0.0005247502,0.00016189521,0.00010233056],"about_ca_topic_score_codex":0.0000030567514,"about_ca_topic_score_gemma":2.9867218e-7,"teacher_disagreement_score":0.0024090707,"about_ca_system_score_codex":0.000025931457,"about_ca_system_score_gemma":0.00008060568,"threshold_uncertainty_score":0.30650342},"labels":[],"label_agreement":null},{"id":"W2042625194","doi":"10.1515/revneuro.2007.18.1.37","title":"Insights into the Role of Dopamine Receptor Systems in Learning and Memory","year":2007,"lang":"en","type":"review","venue":"Reviews in the Neurosciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":175,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute on Drug Abuse; Canada Research Chairs","keywords":"Dopamine; Neuroscience; Dopaminergic; Dopamine receptor D3; Dopamine receptor; Dopamine receptor D2; Schizophrenia (object-oriented programming); Cognition; Dopamine hypothesis of schizophrenia; Psychology; D1-like receptor; D2-like receptor; Mechanism (biology); Dopamine receptor D1; Biology; Disease; Medicine; Psychiatry; Internal medicine","score_opus":0.03484841994411931,"score_gpt":0.32141350690746895,"score_spread":0.28656508696334965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042625194","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017008942,0.9966758,0.000018430115,0.0000047010294,0.00055401283,0.0008127156,5.700786e-7,0.000002048427,0.00023083981],"genre_scores_gemma":[0.001190037,0.9983077,0.00003606823,0.000026353455,0.00013310876,0.00008566998,0.000006007108,0.000013370978,0.00020165715],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99721617,0.0012440041,0.0007200617,0.0004162391,0.00021076377,0.00019276363],"domain_scores_gemma":[0.9990646,0.00015719517,0.00044701522,0.00028537287,0.000017425451,0.000028390388],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0024579149,0.00023705472,0.00079167495,0.000114029695,0.00009754533,0.000047446647,0.0006645318,0.0001467725,0.000003344021],"category_scores_gemma":[0.00039321027,0.00010948841,0.00015158493,0.0005135095,0.00018193209,0.000005460687,0.00014255689,0.0003325296,0.0000025748034],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000017579455,0.000019618294,0.000010370738,0.0018014322,0.0000027353224,0.0000011495023,0.00021952704,0.0000071175255,0.013992351,0.00008229472,0.0000129809205,0.9838487],"study_design_scores_gemma":[0.000032780797,0.00011417597,6.1021035e-7,0.0027696008,0.000020736572,0.000013783626,0.00034266833,0.000020823465,0.0006002009,0.000013921414,0.995949,0.00012171315],"about_ca_topic_score_codex":0.00005038053,"about_ca_topic_score_gemma":0.000026879408,"teacher_disagreement_score":0.995936,"about_ca_system_score_codex":0.000010100416,"about_ca_system_score_gemma":0.000058311696,"threshold_uncertainty_score":0.44648075},"labels":[],"label_agreement":null},{"id":"W2042771012","doi":"10.1139/y02-060","title":"Angiotensin II is bound to both receptors AT<sub>1</sub>and AT<sub>2</sub>, parallel to the transmembrane domains and in an extended form","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Angiotensin II; Angiotensin II receptor type 1; Receptor; Chemistry; Stereochemistry; Transmembrane domain; Angiotensin receptor; Biophysics; Biochemistry; Biology","score_opus":0.011431409872570691,"score_gpt":0.23591640491451393,"score_spread":0.22448499504194325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042771012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934002,0.0023418227,0.0000434265,0.0034518517,0.00045784735,0.00025292457,0.00003201778,0.0000024254439,0.000017493725],"genre_scores_gemma":[0.9918328,0.001508803,0.00011214034,0.0060834405,0.0003688424,0.000012063543,0.0000119952265,0.00002353011,0.000046380897],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985138,0.000188505,0.0003359281,0.0003759247,0.00006558436,0.0005202204],"domain_scores_gemma":[0.998877,0.000035493864,0.00011694043,0.00013255124,0.00007247505,0.0007655457],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003027464,0.00023444142,0.00035468306,0.00016962302,0.0004524271,0.00001856919,0.00017866689,0.00026222464,0.00028463418],"category_scores_gemma":[0.000013628622,0.00019395097,0.0000778303,0.00011428818,0.00021522539,0.000016890162,0.00006678513,0.00024728893,0.000004444445],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037588045,0.000026703792,0.00015458664,0.000013383937,0.000087264125,0.000035414505,0.0012755018,0.00011064553,0.98648345,0.000017093484,0.007986395,0.0034336718],"study_design_scores_gemma":[0.0013693065,0.0014800376,0.003635703,0.000015136721,0.00006124299,0.00028582392,0.00008791371,0.000105787025,0.97358173,0.0002810685,0.01882959,0.00026664682],"about_ca_topic_score_codex":0.000080932674,"about_ca_topic_score_gemma":0.008536882,"teacher_disagreement_score":0.012901714,"about_ca_system_score_codex":0.00005937551,"about_ca_system_score_gemma":0.000101941856,"threshold_uncertainty_score":0.7909091},"labels":[],"label_agreement":null},{"id":"W2043108527","doi":"10.1139/y03-007","title":"Angiotensin II AT<sub>1</sub> receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells","year":2003,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Internalization; Cytosol; Receptor; Vascular smooth muscle; Angiotensin II; Biology; Cell biology; Molecular biology; Endocrinology; Internal medicine; Biochemistry; Medicine","score_opus":0.008051814341207308,"score_gpt":0.2206874646442156,"score_spread":0.2126356503030083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043108527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99777836,0.0014930443,0.00031480967,0.00012706981,0.00018584334,0.00007871806,0.000008373654,0.0000015385102,0.000012257172],"genre_scores_gemma":[0.99814916,0.0010583097,0.00016127224,0.00048734073,0.00011207968,0.0000028214477,0.000005619301,0.000017557044,0.000005837237],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990528,0.00023680073,0.00023143596,0.00019937695,0.00003024913,0.0002493099],"domain_scores_gemma":[0.9994929,0.000017485465,0.000108098364,0.00006003848,0.0000659378,0.00025552968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027843658,0.0001264837,0.00021665802,0.00012441228,0.0001991672,0.000009044457,0.000068033005,0.00019592103,0.000175393],"category_scores_gemma":[0.000020128415,0.00012909752,0.00004721551,0.000054238284,0.00015545987,0.000010058545,0.00001637688,0.00013398645,5.24193e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000340366,0.000015254384,0.00022326651,0.000018494173,0.000059452123,0.000010637662,0.00038669037,0.00019390242,0.99804014,0.000105733714,0.00023161391,0.00068075315],"study_design_scores_gemma":[0.0006774478,0.0002237695,0.0019443149,0.000020470556,0.000044084692,0.000048680224,0.000042016203,0.000106264626,0.9902874,0.00030928076,0.00616161,0.00013464152],"about_ca_topic_score_codex":0.00014812216,"about_ca_topic_score_gemma":0.0005769337,"teacher_disagreement_score":0.0077527463,"about_ca_system_score_codex":0.000035210614,"about_ca_system_score_gemma":0.00012007587,"threshold_uncertainty_score":0.5264444},"labels":[],"label_agreement":null},{"id":"W2043371041","doi":"10.3109/10799893.2012.759592","title":"GPCR Retreat 2012: timing is everything","year":2013,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University; Western University","funders":"Canadian Institutes of Health Research; Medical University of South Carolina; Heart and Stroke Foundation of Canada","keywords":"Tribute; G protein-coupled receptor; Attendance; Marketing buzz; Library science; Environmental ethics; Medicine; Art; Art history; Political science; Philosophy; Computer science; World Wide Web; Receptor","score_opus":0.01178277612762373,"score_gpt":0.22613832714096946,"score_spread":0.21435555101334572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043371041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97628653,0.0021861054,0.02012644,0.00039101843,0.0007322854,0.00009659227,0.0000020376133,0.0000048731667,0.00017411944],"genre_scores_gemma":[0.99306613,0.0015430802,0.003401192,0.00014895227,0.0008883582,0.0000025568982,0.000005488868,0.000020558582,0.0009236901],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999072,0.00005616917,0.0003429997,0.0001677776,0.0001907932,0.00017024601],"domain_scores_gemma":[0.9994103,0.00001066795,0.0001899105,0.00007756872,0.00018607371,0.00012551392],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00030162523,0.00013989107,0.00018936425,0.00008338697,0.00011036605,0.0000641203,0.00008498388,0.00014920215,0.0019292318],"category_scores_gemma":[0.0000121404955,0.00011320323,0.00015433041,0.00006906185,0.000036047797,0.000050906332,0.000011426324,0.00017103774,0.000005789942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054367014,0.000025209078,0.00027672554,0.000015167585,0.00006339629,0.0000011657687,0.00025404457,0.000054692686,0.95726055,0.0000146295615,0.005941927,0.036038116],"study_design_scores_gemma":[0.00060099375,0.00085047004,0.00021371507,0.00008189129,0.000055657525,0.00025087025,0.00060274155,0.0001370239,0.95590234,0.00046804998,0.040611267,0.00022496362],"about_ca_topic_score_codex":0.000016881642,"about_ca_topic_score_gemma":8.9469665e-7,"teacher_disagreement_score":0.035813153,"about_ca_system_score_codex":0.000014554131,"about_ca_system_score_gemma":0.00003086921,"threshold_uncertainty_score":0.99898314},"labels":[],"label_agreement":null},{"id":"W2043514526","doi":"10.1016/j.bpj.2014.11.555","title":"Polymer-Based Nanodiscs for Studying Structure and Dynamics of G-Protein-Coupled Receptors","year":2015,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Rhodopsin; Nanodisc; Micelle; G protein-coupled receptor; Chemistry; Polymer; Lipid bilayer; Integral membrane protein; Biophysics; Membrane; Membrane protein; Ligand (biochemistry); Styrene; Copolymer; Aqueous solution; Biochemistry; Organic chemistry; Receptor; Biology","score_opus":0.01541964711999031,"score_gpt":0.24730942287758126,"score_spread":0.23188977575759095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043514526","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97595364,0.00019195542,0.023304295,0.0001235588,0.00024509357,0.00014224436,0.000028076072,0.0000037937198,0.000007329057],"genre_scores_gemma":[0.99507064,0.000006845874,0.0043523167,0.00003972786,0.0004153049,0.0000041129483,0.00003722079,0.000019771129,0.00005408901],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925303,0.000035623274,0.00020380123,0.00016984386,0.00016096672,0.00017672166],"domain_scores_gemma":[0.9994158,0.0000094700035,0.00015200206,0.00010837201,0.00015255052,0.00016179029],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014558,0.00012832507,0.00018155432,0.00003280329,0.00008175111,0.000033240605,0.0001199838,0.000107924694,0.000012593353],"category_scores_gemma":[0.00004688588,0.00010251958,0.00010301103,0.000053378935,0.00005621786,0.0000048103416,0.00003882077,0.00009623187,2.6359425e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018807212,0.00004321732,0.00012011908,0.00001370745,0.000038133752,7.7907816e-7,0.000027473252,0.000056652956,0.99706286,0.00034396467,0.000057352914,0.002047652],"study_design_scores_gemma":[0.0011282004,0.00089825393,0.000023729968,0.00002265685,0.000024950414,0.000010086362,0.00019588269,0.004713029,0.99219227,0.00042374054,0.00022161953,0.00014558401],"about_ca_topic_score_codex":0.000005527652,"about_ca_topic_score_gemma":0.000002754073,"teacher_disagreement_score":0.019116957,"about_ca_system_score_codex":0.000018819872,"about_ca_system_score_gemma":0.00009867975,"threshold_uncertainty_score":0.41806272},"labels":[],"label_agreement":null},{"id":"W2043820906","doi":"10.3389/fnbeh.2015.00062","title":"Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics","year":2015,"lang":"en","type":"article","venue":"Frontiers in Behavioral Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Neurite; Cofilin; CDC42; Cell biology; Neuroscience; Signal transduction; Actin cytoskeleton; Cytoskeleton; Cyclin-dependent kinase 5; Actin remodeling; Biology; Chemistry; Protein kinase C; Cell; Biochemistry","score_opus":0.034187523817640904,"score_gpt":0.2933506924752826,"score_spread":0.2591631686576417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043820906","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97244734,0.00006309335,0.026347576,0.000040688876,0.0008902628,0.0001639143,0.000018711902,0.0000074085724,0.000021014162],"genre_scores_gemma":[0.9898601,0.00007067283,0.009730449,0.0000661038,0.000028300225,0.000008062681,0.00005134887,0.00001221454,0.00017272503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990424,0.000055319637,0.00019633316,0.0003359726,0.00019462458,0.00017533508],"domain_scores_gemma":[0.9995982,0.0000038611843,0.00011933589,0.0001548305,0.000060328257,0.00006344411],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016050135,0.000115289884,0.00012851985,0.00005625576,0.00004966435,0.00003822158,0.00014957601,0.00009412237,0.0000023975945],"category_scores_gemma":[0.00007657748,0.000117237294,0.000026260803,0.00017362538,0.00010692935,0.00005657259,0.00007524362,0.000086368775,2.2392135e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006108452,0.00007922876,0.05471864,0.000005656124,7.8941224e-7,7.993434e-7,0.00015329143,0.00046618734,0.9409334,0.00002657292,0.0003454046,0.0032089103],"study_design_scores_gemma":[0.00073332794,0.0007861115,0.009293722,0.000032969718,0.000010048982,0.0000034850518,0.00059700635,0.0074703344,0.97923285,0.00028330294,0.0013107781,0.00024606052],"about_ca_topic_score_codex":0.000051584957,"about_ca_topic_score_gemma":0.000004514289,"teacher_disagreement_score":0.04542492,"about_ca_system_score_codex":0.00003511317,"about_ca_system_score_gemma":0.000041809715,"threshold_uncertainty_score":0.4780798},"labels":[],"label_agreement":null},{"id":"W2043825921","doi":"10.1038/nm1753","title":"Functional roles for C5a receptors in sepsis","year":2008,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":381,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Blockade; Sepsis; C5a receptor; Receptor; Medicine; Immunology; Biology; Immune system; Internal medicine; Complement system","score_opus":0.012615211901813033,"score_gpt":0.25806186697467876,"score_spread":0.24544665507286573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043825921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9802467,0.0072824773,0.0073394743,0.0020017475,0.0016078006,0.0002759772,0.000008665852,0.000016939217,0.001220205],"genre_scores_gemma":[0.99322593,0.00034726682,0.0012889381,0.0012586998,0.0014468282,0.000030175152,0.00027076848,0.000017558486,0.0021138492],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929965,0.000018610668,0.00014839391,0.00023335789,0.00014201124,0.0001579523],"domain_scores_gemma":[0.9996925,0.000021278423,0.000039251896,0.00012058539,0.00007458906,0.000051773684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018979366,0.00010518871,0.00013955015,0.00006261514,0.000061333914,0.0000016899363,0.000078633915,0.00030206036,0.00029046994],"category_scores_gemma":[0.00019442062,0.000080988066,0.00005370415,0.000093787596,0.000049019392,0.0000018663617,0.000017401717,0.00017958795,0.0000029925732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001954545,0.000035937665,0.0019941586,0.000015099,0.00002945192,0.0000040273753,0.00011129284,0.000057307683,0.89621663,0.00041688798,0.097735405,0.003188359],"study_design_scores_gemma":[0.0020380414,0.0005380465,0.0020498752,0.000050815306,0.0000145369095,0.000031752556,0.000179808,0.00007740363,0.57421136,0.000447033,0.42016327,0.00019804854],"about_ca_topic_score_codex":0.0000071774202,"about_ca_topic_score_gemma":0.000024502879,"teacher_disagreement_score":0.3224279,"about_ca_system_score_codex":0.000012629671,"about_ca_system_score_gemma":0.0000356964,"threshold_uncertainty_score":0.33025974},"labels":[],"label_agreement":null},{"id":"W2043890741","doi":"10.1074/jbc.m203593200","title":"Phosphorylation-independent Regulation of Metabotropic Glutamate Receptor Signaling by G Protein-coupled Receptor Kinase 2","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; Western University","funders":"","keywords":"Metabotropic glutamate receptor 1; Metabotropic glutamate receptor; Beta adrenergic receptor kinase; G protein-coupled receptor kinase; Phosphorylation; Metabotropic glutamate receptor 6; Cell biology; Biology; Biochemistry; G protein-coupled receptor; Metabotropic glutamate receptor 5; Signal transduction; Chemistry; Receptor; Glutamate receptor","score_opus":0.014105044793175845,"score_gpt":0.21694667029660697,"score_spread":0.20284162550343113,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043890741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949925,0.0033952298,0.0011491369,0.00009285059,0.00013875094,0.00013445609,0.000015978465,0.0000053115887,0.000075763244],"genre_scores_gemma":[0.99624455,0.00036171798,0.0026310866,0.000023961938,0.0002851484,0.000007813694,0.00004639101,0.000015031574,0.0003842974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99840194,0.00007431424,0.00077558454,0.00025601557,0.000260295,0.00023182874],"domain_scores_gemma":[0.9988166,0.000023161778,0.00067361904,0.00016969339,0.00020400273,0.0001129155],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00044702913,0.00019239637,0.00036458005,0.00003196544,0.000042381347,0.000018111841,0.00024059015,0.00034776118,0.002411643],"category_scores_gemma":[0.00020200107,0.0001505969,0.00021957634,0.00011430913,0.000061294835,0.0000110644105,0.000047658017,0.00022761279,0.0000060760785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020369604,0.00017533463,0.00047810614,0.000034797402,0.000045370885,0.0000024939645,0.000017401262,0.0001841238,0.9977593,0.0000077656205,0.00040520134,0.0006864106],"study_design_scores_gemma":[0.0007811724,0.00036076512,0.00009296757,0.00007899046,0.000012276584,0.000008881501,0.000057466455,0.00021123106,0.9949629,0.00009449918,0.003165871,0.00017301698],"about_ca_topic_score_codex":0.0000033497424,"about_ca_topic_score_gemma":1.8655325e-7,"teacher_disagreement_score":0.0030335118,"about_ca_system_score_codex":0.00004261437,"about_ca_system_score_gemma":0.00002716066,"threshold_uncertainty_score":0.9985003},"labels":[],"label_agreement":null},{"id":"W2044110727","doi":"10.1073/pnas.0604717103","title":"Ancestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptors","year":2006,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Metabotropic glutamate receptor; Receptor; Biology; Glutamate receptor; Metabotropic receptor; Class C GPCR; Neurotransmission; Rhodopsin-like receptors; Metabotropic glutamate receptor 2; Biochemistry; Cell biology","score_opus":0.023827012590671527,"score_gpt":0.26445102697000744,"score_spread":0.24062401437933592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044110727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99838537,0.00014524549,0.0000041468315,0.00018353092,0.000054045388,0.00017234325,0.000009716461,0.0000018547911,0.0010437494],"genre_scores_gemma":[0.9980729,0.000018859793,0.0016565355,0.000020169642,0.000086748754,0.0000053169692,3.0963056e-7,0.000003299251,0.00013582164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885744,0.0000069828984,0.00034275008,0.00016895028,0.0005195344,0.000104314866],"domain_scores_gemma":[0.99908227,0.00001179281,0.00064933894,0.000011236743,0.00023312532,0.000012261118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073532586,0.00007427084,0.00012387907,0.000057241195,0.00010765898,0.0000075412404,0.0004647149,0.000099057295,0.000008242843],"category_scores_gemma":[0.0001463565,0.000045354594,0.00010568836,0.0003502347,0.0005121711,0.00002230539,0.000077752054,0.000075578035,8.716554e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014739636,0.000016536167,0.003253456,0.000033312925,0.00000840435,3.6461945e-10,0.000017862048,0.000086516986,0.99273795,0.0035152154,0.00008180372,0.00023422916],"study_design_scores_gemma":[0.00011978918,0.00006354037,0.0057112225,0.00010983497,0.000006754745,0.0000029509386,0.0001536131,0.00012998318,0.9857496,0.007853349,0.000048960723,0.000050416977],"about_ca_topic_score_codex":0.000016654933,"about_ca_topic_score_gemma":1.3690475e-7,"teacher_disagreement_score":0.0069883387,"about_ca_system_score_codex":0.000009391963,"about_ca_system_score_gemma":0.00004566427,"threshold_uncertainty_score":0.18871155},"labels":[],"label_agreement":null},{"id":"W2044168459","doi":"10.1242/jcs.085795","title":"WDR36 acts as a scaffold protein tethering a G-protein-coupled receptor, Gαq and phospholipase Cβ in a signalling complex","year":2011,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Biology; Cell biology; Scaffold protein; Immunoprecipitation; G protein-coupled receptor; Gq alpha subunit; Gene knockdown; Colocalization; G protein; HEK 293 cells; Proximity ligation assay; Receptor; Context (archaeology); Phospholipase; Signal transduction; Biochemistry; Gene","score_opus":0.02235000195181441,"score_gpt":0.23784858312416432,"score_spread":0.2154985811723499,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044168459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963449,0.0004150191,0.0021198508,0.000034126435,0.00008185181,0.00020789714,6.658677e-7,0.0000034369907,0.0007922032],"genre_scores_gemma":[0.9836288,0.000070691705,0.015991636,0.000065315515,0.000084108906,0.000005940486,4.5164833e-7,0.000013952719,0.00013907693],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861485,0.000042915988,0.00037831516,0.000277904,0.00034435888,0.00034168683],"domain_scores_gemma":[0.9991629,0.0000076007973,0.0003194713,0.00012877354,0.00016696972,0.00021429607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013428803,0.00014845708,0.00020358802,0.0001320069,0.000121676734,0.00007024561,0.00037025116,0.00008427218,0.00019277129],"category_scores_gemma":[0.000117139716,0.00012446754,0.000070114416,0.000263321,0.00016182222,0.000034935503,0.00011941974,0.00016346095,0.0000044455383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013643621,0.000067914996,0.00006496021,0.000015615286,0.000005234507,0.000019081392,0.00037295427,0.000033638706,0.9984488,0.000068015455,0.000004846387,0.0007624879],"study_design_scores_gemma":[0.00059071754,0.0006300187,0.000116199815,0.00012813167,0.000005021703,0.00003741285,0.0002997227,0.0006270669,0.9965341,0.00031500225,0.00055322866,0.00016338249],"about_ca_topic_score_codex":0.00006851954,"about_ca_topic_score_gemma":0.00001091818,"teacher_disagreement_score":0.013871784,"about_ca_system_score_codex":0.0000323292,"about_ca_system_score_gemma":0.0002525098,"threshold_uncertainty_score":0.5075639},"labels":[],"label_agreement":null},{"id":"W2044200819","doi":"10.1021/ac0709495","title":"Two-Photon Excitation Fluorescence Cross-Correlation Assay for Ligand−Receptor Binding:  Cell Membrane Nanopatches Containing the Human μ-Opioid Receptor","year":2007,"lang":"en","type":"article","venue":"Analytical Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina; University of Calgary","funders":"","keywords":"Chemistry; Receptor; Ligand (biochemistry); Dissociation constant; Opioid receptor; Biophysics; G protein-coupled receptor; Fluorescence; Stereochemistry; Enkephalin; Fluorescence correlation spectroscopy; Cell membrane; Membrane; Biochemistry; Opioid; Molecule","score_opus":0.014265783333198633,"score_gpt":0.2864602967625357,"score_spread":0.2721945134293371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044200819","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9826966,0.00012208898,0.014632331,0.000060414684,0.0002174291,0.00028706912,0.000032925196,0.00003126372,0.0019198774],"genre_scores_gemma":[0.9928208,0.000024142804,0.0016433117,0.000099080105,0.0007510317,0.000036038287,0.0008381441,0.000044735018,0.0037427288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981459,0.00003246086,0.00049258594,0.00055403175,0.00028230445,0.0004927423],"domain_scores_gemma":[0.99887145,0.00017447407,0.00021511795,0.00034139495,0.00023251123,0.00016505549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001306049,0.00027315324,0.00023408148,0.000029517754,0.00040203892,0.00012590342,0.00031312276,0.00033480127,0.00021959595],"category_scores_gemma":[0.00034147463,0.00022866517,0.00022785642,0.00014940636,0.00015045848,0.000015533153,0.00006899734,0.00023508933,0.000025454694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015456192,0.00005646818,0.0015554812,0.000071029965,0.000039446168,9.503871e-7,0.00009932361,0.000046002173,0.9970586,0.00022136373,0.00039137658,0.00030542395],"study_design_scores_gemma":[0.0008501704,0.00013768772,0.000084741514,0.000036195917,0.00004580904,0.000003120999,0.00046376104,0.001162093,0.9926901,0.00010891466,0.004109223,0.00030816876],"about_ca_topic_score_codex":0.000018095185,"about_ca_topic_score_gemma":0.0000042820893,"teacher_disagreement_score":0.01298902,"about_ca_system_score_codex":0.00006154829,"about_ca_system_score_gemma":0.000074264186,"threshold_uncertainty_score":0.9324695},"labels":[],"label_agreement":null},{"id":"W2044570582","doi":"10.1074/jbc.m204163200","title":"β1/β2-Adrenergic Receptor Heterodimerization Regulates β2-Adrenergic Receptor Internalization and ERK Signaling Efficacy","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":213,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; Montreal Heart Institute","funders":"Heart and Stroke Foundation of Canada","keywords":"Internalization; Receptor; Cell biology; G protein-coupled receptor; Signal transduction; MAPK/ERK pathway; Agonist; HEK 293 cells; Phosphorylation; Adenylyl cyclase; Biology; Stimulation; Chemistry; Biochemistry; Endocrinology","score_opus":0.01860360609101906,"score_gpt":0.22570534507398926,"score_spread":0.2071017389829702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044570582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919759,0.0036369823,0.0036326007,0.00012378297,0.0003090929,0.000080937294,0.00001155217,0.000019555484,0.00020960036],"genre_scores_gemma":[0.9932123,0.00262047,0.0022618948,0.00018543303,0.0011310983,0.0000042084066,0.00013582375,0.00003053397,0.0004182761],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981585,0.00012063414,0.00074405456,0.00042072358,0.00024016632,0.00031589402],"domain_scores_gemma":[0.9986155,0.000048055877,0.00062407454,0.00020888042,0.00022801147,0.00027549584],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00037990295,0.0003093934,0.00040187483,0.00005025079,0.00012875689,0.00008373225,0.00029925452,0.0004755032,0.0014869504],"category_scores_gemma":[0.00043151443,0.00023863703,0.00023955472,0.00015017194,0.00012663365,0.000019189216,0.000112859154,0.00026083618,0.000008046563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015076698,0.00011772788,0.0005997629,0.000027204354,0.00008600087,0.000005167578,0.000046618665,0.0005481066,0.9951531,0.000015369416,0.00078197406,0.0024681475],"study_design_scores_gemma":[0.0008129381,0.00047250715,0.000081871876,0.000117934236,0.00003161781,0.00011596964,0.000072107214,0.0003364172,0.99025357,0.000078830606,0.007313315,0.0003129235],"about_ca_topic_score_codex":0.0000021170626,"about_ca_topic_score_gemma":1.5541694e-7,"teacher_disagreement_score":0.0065313405,"about_ca_system_score_codex":0.00003614936,"about_ca_system_score_gemma":0.00002655616,"threshold_uncertainty_score":0.9994258},"labels":[],"label_agreement":null},{"id":"W2044730918","doi":"10.1016/s0014-2999(01)01626-0","title":"Pharmacological characterisation of the goldfish somatostatin sst5 receptor","year":2002,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"University of Alberta","keywords":"Radioligand; Agonist; Receptor; Somatostatin receptor; Somatostatin; GTP'; Biology; Internal medicine; Guanosine; Endocrinology; Somatostatin receptor 2; Radioligand Assay; Molecular biology; Chemistry; Biochemistry; Medicine","score_opus":0.019245011463271885,"score_gpt":0.24982609173238146,"score_spread":0.23058108026910956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044730918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954254,0.00044338428,0.00059691403,0.0007995286,0.0016872181,0.00010591248,0.000009098699,0.000004056691,0.0009284578],"genre_scores_gemma":[0.9966418,0.0004748483,0.000598795,0.0010009079,0.0009244598,0.0000012082593,0.0000033360539,0.000021126094,0.00033350673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982218,0.00081576785,0.00050673675,0.00013201349,0.00015034633,0.00017335021],"domain_scores_gemma":[0.9990492,0.00002376755,0.0006163507,0.00008440463,0.00015693024,0.00006938112],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00066457776,0.000118887394,0.0001793254,0.000042391224,0.000065296554,0.000009937805,0.00038749512,0.000043421187,0.0031158573],"category_scores_gemma":[0.000058917172,0.00008211788,0.00017813097,0.00008186029,0.0000967876,0.000008001585,0.00010003521,0.00020989504,0.000026271531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000087532,0.00010635765,0.00021001126,0.0000067408637,0.000097290766,0.000012670625,0.00013177778,0.000048528567,0.9582984,0.000010683238,0.03671626,0.004273759],"study_design_scores_gemma":[0.0011225151,0.0005611596,0.0008553639,0.0000120330105,0.0000645758,0.00008941973,0.000044382305,0.0000810788,0.9190803,0.0000058778064,0.07799277,0.00009049368],"about_ca_topic_score_codex":2.516302e-7,"about_ca_topic_score_gemma":7.0811595e-8,"teacher_disagreement_score":0.041276507,"about_ca_system_score_codex":0.0000126551895,"about_ca_system_score_gemma":0.000022064694,"threshold_uncertainty_score":0.9977954},"labels":[],"label_agreement":null},{"id":"W2044805801","doi":"10.1096/fj.07-9435com","title":"Ligation of the adhesion‐GPCR EMR2 regulates human neutrophil function","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Thomas Hospital","funders":"Medical Research Council","keywords":"Cell biology; G protein-coupled receptor; Innate immune system; Cell adhesion; Proinflammatory cytokine; Receptor; Inflammation; Adhesion; Biology; Signal transduction; Chemistry; Immunology; Biochemistry","score_opus":0.010887440158102321,"score_gpt":0.23175339279856355,"score_spread":0.22086595264046122,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044805801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959103,0.00033692858,0.002877586,0.00013612022,0.00037044563,0.00006243806,0.0000010596128,0.0000029656553,0.00030219546],"genre_scores_gemma":[0.9987115,0.000043843622,0.000084081425,0.00012512253,0.00059827,6.4330965e-7,0.0000049834457,0.000009668887,0.00042185522],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993524,0.000064066604,0.00021181632,0.00008343851,0.00015619029,0.00013210063],"domain_scores_gemma":[0.9994837,0.000009530237,0.0001922627,0.0001890757,0.00008776224,0.000037648206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007089984,0.000072744326,0.00006580614,0.000021626587,0.0003248748,0.000021518757,0.00018546412,0.00007142398,0.00007816874],"category_scores_gemma":[0.000022680193,0.00003933001,0.000118924814,0.00006474392,0.000048873153,0.0000037657378,0.000043134354,0.00013719073,0.0000020896675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049746755,0.0000129632035,0.00043676497,0.000002292631,0.000022502536,4.772901e-7,0.000046614343,0.00012432298,0.9971458,0.00035328348,0.00029659696,0.0015086855],"study_design_scores_gemma":[0.00019517608,0.00018311854,0.005571458,0.00001979732,0.000024272567,0.00004551534,0.0001466858,0.000014480945,0.9912592,0.0016879871,0.0008002781,0.000051994375],"about_ca_topic_score_codex":0.000005687841,"about_ca_topic_score_gemma":0.0000067304713,"teacher_disagreement_score":0.0058865137,"about_ca_system_score_codex":0.0000096803915,"about_ca_system_score_gemma":0.000024239704,"threshold_uncertainty_score":0.24987072},"labels":[],"label_agreement":null},{"id":"W2044995947","doi":"10.1016/j.nucmedbio.2012.10.013","title":"Analysis of [11C]methyl-candesartan kinetics in the rat kidney for the assessment of angiotensin II type 1 receptor density in vivo with PET","year":2013,"lang":"en","type":"article","venue":"Nuclear Medicine and Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Candesartan; Angiotensin II receptor type 1; Angiotensin II; Receptor; Radioligand; Kidney; Internal medicine; Endocrinology; In vivo; Angiotensin receptor; Medicine; Renin–angiotensin system; Pharmacology; Chemistry; Biology; Blood pressure","score_opus":0.0203521626678525,"score_gpt":0.288667718927988,"score_spread":0.2683155562601355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044995947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969216,0.00020654705,0.00026590182,0.0021946055,0.00006420046,0.00025095633,0.000008445289,0.0000012738548,0.0000864929],"genre_scores_gemma":[0.9972548,0.00032562687,0.0012291808,0.0010531783,0.000058656107,0.000006267501,0.00003957125,0.000006759667,0.000025985793],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993405,0.00009545603,0.00021236834,0.00016737371,0.000057352383,0.00012699825],"domain_scores_gemma":[0.99948937,0.00007980248,0.000100652775,0.00018562016,0.00011406841,0.00003047399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040980888,0.00008984591,0.00027500556,0.000082786995,0.000034990997,0.0000028990028,0.00011852101,0.00008032295,0.00017513493],"category_scores_gemma":[0.000091109134,0.00004277986,0.000043768647,0.0002540224,0.00017717159,0.0000018581281,0.00003954386,0.00007067064,1.1947867e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006961738,0.000039933468,0.00789146,0.000008670426,0.00013953302,3.1891764e-7,0.00029557422,0.000013250522,0.988334,0.00029002188,0.002290253,0.0006273388],"study_design_scores_gemma":[0.012048787,0.043233935,0.21161817,0.0004158562,0.0033489952,0.00006745012,0.022710165,0.023374872,0.4162376,0.0011862222,0.2644339,0.0013240592],"about_ca_topic_score_codex":0.00039967062,"about_ca_topic_score_gemma":0.00025476454,"teacher_disagreement_score":0.57209647,"about_ca_system_score_codex":0.00000490621,"about_ca_system_score_gemma":0.00002544756,"threshold_uncertainty_score":0.19176047},"labels":[],"label_agreement":null},{"id":"W2045436741","doi":"10.1016/j.mce.2006.12.027","title":"Angiotensin II activates p44/42 MAP kinase partly through PKCɛ in H295R cells","year":2007,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Protein kinase C; MAPK/ERK pathway; Angiotensin II; JUNB; Gene knockdown; Molecular biology; Signal transduction; Gene isoform; Cell biology; Biology; Gene expression; Chemistry; Endocrinology; Gene; Biochemistry","score_opus":0.007854601462347547,"score_gpt":0.22779534332195137,"score_spread":0.21994074185960383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045436741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96576524,0.0059133144,0.026672777,0.00024662586,0.00035814175,0.00023598818,0.0000064394912,0.000024856417,0.00077660044],"genre_scores_gemma":[0.9959282,0.00021876056,0.0024274567,0.0006651114,0.00016914634,0.00001324727,0.00009042867,0.00004834794,0.00043928524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978791,0.000105597486,0.00036208783,0.00067803316,0.00014802063,0.00082716544],"domain_scores_gemma":[0.9992972,0.000018041055,0.00009137961,0.00041186513,0.000056298355,0.00012521399],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021547894,0.00031995453,0.00033287387,0.0001152863,0.00014035021,0.000025115343,0.00020044022,0.00029085213,0.00007690544],"category_scores_gemma":[0.000025611966,0.00032497026,0.00014883635,0.0001373172,0.00013382203,0.000008934591,0.00026897763,0.00023908322,0.000014098127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010786933,0.00010459901,0.00021333613,0.000016502343,0.00005353891,0.00058490766,0.000114761795,0.000071281,0.9946977,0.0016324763,0.00027461335,0.0021284395],"study_design_scores_gemma":[0.0008559727,0.00040161185,0.000041959658,0.000015047671,0.000022891263,0.00005367245,0.0002139182,0.000032297237,0.95627016,0.0008852151,0.04085675,0.0003505135],"about_ca_topic_score_codex":0.00009852323,"about_ca_topic_score_gemma":0.00003944031,"teacher_disagreement_score":0.040582135,"about_ca_system_score_codex":0.000019485724,"about_ca_system_score_gemma":0.000035409666,"threshold_uncertainty_score":0.99992025},"labels":[],"label_agreement":null},{"id":"W2045886309","doi":"10.1016/j.bbrc.2008.10.044","title":"Roles of G protein and β-arrestin in dopamine D 2 receptor-mediated ERK activation","year":2008,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Arrestin; MAPK/ERK pathway; Pertussis toxin; Cell biology; G protein; Dopamine; G protein-coupled receptor; Chemistry; Receptor; BETA (programming language); Biology; Phosphorylation; Signal transduction; Biochemistry; Endocrinology","score_opus":0.05433139521299541,"score_gpt":0.3248421358248343,"score_spread":0.2705107406118389,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2045886309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99801725,0.00091052457,0.000047379857,0.0006349696,0.000004007831,0.00021842659,0.000015949145,0.0000056938316,0.00014577812],"genre_scores_gemma":[0.99612415,0.0015667857,0.001927948,0.000014124407,0.000045319866,0.000059058213,0.00018281223,0.000008708621,0.00007109301],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990513,0.00015910185,0.00018941674,0.00022233093,0.0001914187,0.00018647095],"domain_scores_gemma":[0.99918175,0.00012548568,0.000040830208,0.00039707773,0.00015747407,0.000097373995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029041097,0.00008720872,0.00012925167,0.00006918963,0.0001298178,0.000010146042,0.00025795153,0.000119843775,0.000009447117],"category_scores_gemma":[0.0005295099,0.000075828975,0.00002480479,0.00024464133,0.0006245478,0.000006408991,0.00033490764,0.00023232013,0.0000026444586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006524285,0.00017731791,0.00028403834,0.000017817982,0.000007058321,2.1244057e-7,0.000043352775,1.7863108e-7,0.9973121,0.00063299626,0.00013674787,0.0013228831],"study_design_scores_gemma":[0.000303762,0.00019031853,0.0013448477,0.000054799533,0.0000012609769,0.0000015954788,0.00008198303,0.00020443577,0.9945601,0.00026053714,0.0029041735,0.00009214891],"about_ca_topic_score_codex":0.00007829451,"about_ca_topic_score_gemma":0.000008986919,"teacher_disagreement_score":0.0027674255,"about_ca_system_score_codex":0.000010550968,"about_ca_system_score_gemma":0.000055185094,"threshold_uncertainty_score":0.3092216},"labels":[],"label_agreement":null},{"id":"W2046833185","doi":"10.1074/jbc.m303384200","title":"Receptor Trafficking via the Perinuclear Recycling Compartment Accompanied by Cell Division Is Necessary for Permanent Neurotensin Cell Sensitization and Leads to Chronic Mitogen-activated Protein Kinase Activation","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University","funders":"Institut National de la Santé et de la Recherche Médicale; Association pour la Recherche sur le Cancer; Sanofi","keywords":"Cell biology; Receptor; Biology; Neurotensin receptor; Endocytosis; Cell surface receptor; Cell; Protein kinase A; Homologous desensitization; Agonist; Neurotensin; Kinase; Biochemistry; Neuropeptide","score_opus":0.014551919967025642,"score_gpt":0.23721371607405997,"score_spread":0.22266179610703432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046833185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903975,0.00036227715,0.007823034,0.000929115,0.00009793624,0.00035660114,0.0000118035205,0.000007471274,0.0000142679855],"genre_scores_gemma":[0.997921,0.00009723594,0.001157283,0.0002787461,0.00038907587,0.000009522551,0.00007750508,0.000020803647,0.000048836493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989096,0.00005221472,0.00037010995,0.00029130603,0.00015573039,0.00022106894],"domain_scores_gemma":[0.9992555,0.000028455157,0.00031594984,0.00013209693,0.00014770603,0.00012031138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023617395,0.00019613003,0.00022261609,0.000017221115,0.00018248125,0.000056729154,0.0001576579,0.00019805234,0.00003168293],"category_scores_gemma":[0.000052552266,0.00013475903,0.000121785706,0.00006943232,0.00004033031,0.000011084232,0.000073621195,0.00019474792,0.0000011206192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002948438,0.00009416113,0.000026452257,0.000045563975,0.000014725116,0.0000010547757,0.00008572256,0.001330817,0.99681044,5.8213726e-7,0.0003839713,0.0009116818],"study_design_scores_gemma":[0.00095626205,0.00072348135,0.00006834724,0.00007120106,0.000012701376,0.000012577082,0.00011565131,0.00016363384,0.9946715,0.000018061903,0.0030111724,0.00017538197],"about_ca_topic_score_codex":0.0000023272194,"about_ca_topic_score_gemma":1.5093427e-7,"teacher_disagreement_score":0.0075234976,"about_ca_system_score_codex":0.00007807631,"about_ca_system_score_gemma":0.000045199933,"threshold_uncertainty_score":0.5495314},"labels":[],"label_agreement":null},{"id":"W2046934244","doi":"10.1016/s0039-128x(00)00235-x","title":"Correlation between different gene expression assays designed to measure trans-activation potencies of systemic glucocorticoids","year":2001,"lang":"en","type":"article","venue":"Steroids","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Institut National de la Santé et de la Recherche Médicale","keywords":"Betamethasone; Glucocorticoid receptor; Tyrosine aminotransferase; Antiglucocorticoid; Glucocorticoid; Endogeny; Gene expression; Triamcinolone acetonide; Dexamethasone; Endocrinology; Receptor; Chemistry; Internal medicine; Pharmacology; Biology; Gene; Enzyme; Biochemistry; Enzyme inducer; Medicine; Immunology","score_opus":0.019433379143677997,"score_gpt":0.23581965533657998,"score_spread":0.216386276192902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046934244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5691121,0.00009955939,0.43044317,0.000016266418,0.00007904884,0.00018872207,0.000005485024,0.0000089065215,0.000046705656],"genre_scores_gemma":[0.99828535,0.000038466445,0.001168838,0.000026346368,0.00018640942,0.000028178987,0.00010020689,0.000021642129,0.00014457617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892306,0.00010068468,0.00030828387,0.00025899708,0.00023050279,0.00017845698],"domain_scores_gemma":[0.99944955,0.000014655682,0.00011285621,0.00022775204,0.00011247309,0.00008272272],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017885945,0.00015151262,0.00019990624,0.00005978416,0.00006799076,0.000016034202,0.000102884835,0.00016751222,0.000031486834],"category_scores_gemma":[0.000038163736,0.00012997793,0.00008073453,0.00008945926,0.000015230951,0.000007877409,0.000030259593,0.000057253576,0.0000025236584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000111807756,0.000023233057,0.0086944355,0.000019325207,0.000023116607,5.730157e-7,0.00022008386,0.00045137317,0.98625624,0.000007709313,0.000028453107,0.0041636713],"study_design_scores_gemma":[0.00043627623,0.0004171164,0.006274706,0.00013058857,0.00002326053,0.000006085015,0.00016806951,0.000067164125,0.9922148,0.00003698676,0.000076400785,0.0001485745],"about_ca_topic_score_codex":0.000009743364,"about_ca_topic_score_gemma":0.00000239313,"teacher_disagreement_score":0.42927432,"about_ca_system_score_codex":0.00002816145,"about_ca_system_score_gemma":0.00002491243,"threshold_uncertainty_score":0.5300346},"labels":[],"label_agreement":null},{"id":"W2047153354","doi":"10.1002/jmr.1086","title":"Rhodopsin is spatially heterogeneously distributed in rod outer segment disk membranes","year":2011,"lang":"en","type":"article","venue":"Journal of Molecular Recognition","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Rhodopsin; Peripherin; Biophysics; Membrane; Transducin; Lipid bilayer; Crystallography; Biology; Membrane protein; Chemistry; Retinal; Biochemistry","score_opus":0.02391546208176039,"score_gpt":0.23274289987562122,"score_spread":0.20882743779386082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047153354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94475967,0.0005134028,0.05415608,0.000077491226,0.00022888568,0.00011838005,0.000029257817,0.0000035007781,0.00011334583],"genre_scores_gemma":[0.9921689,0.0002467469,0.0069830376,0.00031995142,0.00015144431,0.000005336386,0.00008502497,0.000024727342,0.0000148169065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882084,0.000120627155,0.00046666156,0.00019147541,0.00020633129,0.00019407795],"domain_scores_gemma":[0.99928296,0.000004183341,0.0002909736,0.00013880558,0.0001902163,0.000092873226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031578567,0.0001552876,0.00020506656,0.00009671343,0.000028936474,0.000024203942,0.0001437798,0.000143544,0.00021783888],"category_scores_gemma":[0.000047494203,0.00014089113,0.00020701294,0.000076839024,0.000020353957,0.000011243193,0.000039164832,0.00012589007,0.0000096095855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024838882,0.0001490141,0.00029255234,0.00001927268,0.00008983574,0.0001796853,0.00014669959,0.00005905292,0.986739,0.0000033932054,0.00008378185,0.011989345],"study_design_scores_gemma":[0.00082629407,0.0005637417,0.00026873854,0.00007546061,0.00004562132,0.0002415878,0.00006197022,0.000043032494,0.9963777,0.00075622223,0.00056047656,0.0001791617],"about_ca_topic_score_codex":0.000018434665,"about_ca_topic_score_gemma":0.000011845223,"teacher_disagreement_score":0.04740926,"about_ca_system_score_codex":0.000024957522,"about_ca_system_score_gemma":0.00004691236,"threshold_uncertainty_score":0.5745374},"labels":[],"label_agreement":null},{"id":"W2047689005","doi":"10.1093/database/baq018","title":"The systematic annotation of the three main GPCR families in Reactome","year":2010,"lang":"en","type":"article","venue":"Database","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"National Human Genome Research Institute; Sixth Framework Programme; National Institutes of Health; European Commission","keywords":"G protein-coupled receptor; UniProt; Computational biology; Computer science; Annotation; Database; Biology; Bioinformatics; Receptor; Gene; Genetics","score_opus":0.00734967211467777,"score_gpt":0.22838758613593957,"score_spread":0.2210379140212618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047689005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983777,0.00019124665,0.00070320826,0.000059286565,0.00024205954,0.00023216894,0.00008273004,0.0000022381112,0.00010936396],"genre_scores_gemma":[0.99942344,0.000046076184,0.00027742633,0.000035752364,0.000044233566,0.00002222631,0.000088444314,0.0000064380692,0.000055962817],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994768,0.000053822318,0.0001709313,0.0001056718,0.00009837267,0.00009441397],"domain_scores_gemma":[0.99938565,0.000036174024,0.00008267142,0.00045282676,0.000027326267,0.000015346133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004999685,0.00005839996,0.00007513304,0.000014569296,0.000058609578,0.000012917725,0.00021345586,0.000043541142,0.000008333883],"category_scores_gemma":[0.00025511184,0.000031142517,0.000036214125,0.00006679855,0.00004321517,0.0000033133615,0.00007847276,0.000085708474,0.0000025749373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009405615,0.00001033969,0.00046229266,0.00016970719,0.000006147697,4.1547057e-7,0.000035045934,0.0000044814883,0.9976363,0.001398795,0.0001291093,0.00013793347],"study_design_scores_gemma":[0.00025225434,0.000033162767,0.0019280846,0.00023547644,0.000014122989,0.0000069699217,0.0004614482,0.00040585786,0.99466324,0.00038433186,0.0015203113,0.00009472418],"about_ca_topic_score_codex":0.00006971824,"about_ca_topic_score_gemma":0.0014880089,"teacher_disagreement_score":0.0029730708,"about_ca_system_score_codex":0.0000028304696,"about_ca_system_score_gemma":0.000027189897,"threshold_uncertainty_score":0.1269955},"labels":[],"label_agreement":null},{"id":"W2047816001","doi":"10.1111/j.1582-4934.2008.00308.x","title":"Src promotes delta opioid receptor (DOR) desensitization by interfering with receptor recycling","year":2008,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institut universitaire en santé mentale de Montréal","funders":"","keywords":"Desensitization (medicine); Proto-oncogene tyrosine-protein kinase Src; Homologous desensitization; Internalization; δ-opioid receptor; Receptor; Cell biology; Agonist; Src family kinase; Biology; Pharmacology; Chemistry; Signal transduction; Biochemistry","score_opus":0.007679852269740647,"score_gpt":0.21426185609313447,"score_spread":0.2065820038233938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047816001","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7983125,0.0060854973,0.19485855,0.00029155216,0.00022224935,0.000117872,0.00000271716,0.0000061472906,0.00010294679],"genre_scores_gemma":[0.9900755,0.0021208657,0.0067575956,0.00028750973,0.00045344746,0.0000024339752,0.00009050802,0.000043827786,0.00016825466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986636,0.000091548274,0.00045706797,0.0002451665,0.00032110128,0.00022150954],"domain_scores_gemma":[0.9990088,0.000015348998,0.00031843787,0.00016557686,0.00029162693,0.00020023537],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043027522,0.00021283596,0.0003376885,0.00009812831,0.00011329193,0.000015619396,0.00013195441,0.00013814539,0.00006879511],"category_scores_gemma":[0.0001472502,0.00015625659,0.00007811881,0.0001132514,0.00012751999,0.000013978486,0.000042739808,0.00020188726,0.0000012169011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019531269,0.000034149958,0.00016285028,0.00003058019,0.00009939793,0.000058053356,0.00026907478,0.000026419932,0.99591386,0.000017429811,0.0015496559,0.001643209],"study_design_scores_gemma":[0.0011653278,0.0017748257,0.000010416943,0.00026234784,0.000056910874,0.00042737334,0.00023534593,0.00007628647,0.97634214,0.000029012861,0.019428972,0.0001910492],"about_ca_topic_score_codex":0.00001048404,"about_ca_topic_score_gemma":9.890681e-7,"teacher_disagreement_score":0.19176309,"about_ca_system_score_codex":0.00001778964,"about_ca_system_score_gemma":0.000070052316,"threshold_uncertainty_score":0.6371959},"labels":[],"label_agreement":null},{"id":"W2047844782","doi":"10.1038/sj.cr.7290083","title":"The angiotensin II type 1 receptor and receptor-associated proteins","year":2001,"lang":"en","type":"review","venue":"Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":192,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôtel-Dieu de Montréal; Université de Montréal","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Biology; Heterotrimeric G protein; Angiotensin II; Cell biology; Signal transduction; Enzyme-linked receptor; Angiotensin II receptor type 1; Receptor; 5-HT5A receptor; G protein-coupled receptor; Protease-activated receptor 2; G protein; G protein-coupled receptor kinase; Internalization; Interleukin-21 receptor; Biochemistry","score_opus":0.08945142847484785,"score_gpt":0.3728071851214014,"score_spread":0.28335575664655355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047844782","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00060141773,0.9959055,0.000012595443,0.0000679465,0.0003449118,0.00114571,0.000025910493,0.000015589969,0.0018804007],"genre_scores_gemma":[0.00006346897,0.9608369,0.00020491038,0.000013380068,0.00057067967,0.00010719884,0.0004086052,0.00009507137,0.037699822],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967882,0.00084187713,0.0003977866,0.0006935487,0.00049193157,0.0007866615],"domain_scores_gemma":[0.9983595,0.0001556187,0.00016324203,0.00063828676,0.0004843487,0.0001990148],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023811131,0.00034340358,0.00058659766,0.0001116969,0.0010021513,0.00016383751,0.00056305644,0.0007818787,0.00025841087],"category_scores_gemma":[0.0004497194,0.00023050506,0.00024457902,0.00059846725,0.00022231389,0.0000029889065,0.000643546,0.00082926155,0.00014831836],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004166343,0.000100347126,0.0000012156565,0.000695001,0.00013072201,0.000005112554,0.00003770969,1.9088641e-7,0.039424643,0.00005943972,0.081386104,0.87811786],"study_design_scores_gemma":[0.00013165499,0.0005728087,1.6721847e-7,0.0008218905,0.00003424914,0.000005437971,0.00004057873,0.0000018302483,0.006119834,0.00003093241,0.99197227,0.0002683216],"about_ca_topic_score_codex":0.00003703478,"about_ca_topic_score_gemma":0.000019574363,"teacher_disagreement_score":0.9105862,"about_ca_system_score_codex":0.00008533736,"about_ca_system_score_gemma":0.0005099174,"threshold_uncertainty_score":0.93997234},"labels":[],"label_agreement":null},{"id":"W2047943968","doi":"10.1016/j.pneurobio.2006.07.003","title":"The mysterious trace amines: Protean neuromodulators of synaptic transmission in mammalian brain","year":2006,"lang":"en","type":"review","venue":"Progress in Neurobiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":216,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nova Scotia Department of Agriculture","funders":"","keywords":"Dopamine; Neurotransmitter; Biogenic amine; Neurotransmission; Serotonin; Neuroscience; Reuptake; Neurotransmitter receptor; Chemistry; Catecholamine; Synaptic cleft; Receptor; Postsynaptic potential; Biology; Biochemistry","score_opus":0.016220013962843404,"score_gpt":0.2933137265740127,"score_spread":0.27709371261116933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047943968","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020822048,0.9771889,0.00004758354,0.00006729055,0.00032222798,0.0014977006,0.000019568646,0.000011390974,0.000023308843],"genre_scores_gemma":[0.02497553,0.97384536,0.00017535307,0.000024505647,0.00012642791,0.00043657207,0.00017773778,0.000099183315,0.00013933194],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967158,0.00091349805,0.001040584,0.00072214624,0.00009743273,0.00051058107],"domain_scores_gemma":[0.99883735,0.00011533924,0.00046941778,0.00049531134,0.000031031206,0.0000515324],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003714227,0.00045621267,0.0010449766,0.00017323717,0.000056270375,0.000022482844,0.0006346446,0.00062986417,0.0000067424758],"category_scores_gemma":[0.00006504289,0.00031159585,0.00031123264,0.00027110754,0.00024300594,0.0000030793283,0.000125705,0.000427388,0.0000017785169],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061235725,0.00014166441,0.00025406844,0.0036830695,0.00004569629,0.000050895076,0.000027144319,0.000017308597,0.004681223,0.000059243488,0.000066958324,0.9909115],"study_design_scores_gemma":[0.00049332454,0.00088355783,0.0000850268,0.0023491725,0.00006684381,0.00013527616,0.000010286994,0.000033635482,0.0026607744,0.000046983467,0.99275345,0.00048167768],"about_ca_topic_score_codex":0.00001430604,"about_ca_topic_score_gemma":0.00005068737,"teacher_disagreement_score":0.9926865,"about_ca_system_score_codex":0.000022109954,"about_ca_system_score_gemma":0.00009879259,"threshold_uncertainty_score":0.9999336},"labels":[],"label_agreement":null},{"id":"W2048117036","doi":"10.1111/j.1600-0854.2009.00932.x","title":"Functional Rescue of β<sub>1</sub>‐Adrenoceptor Dimerization and Trafficking by Pharmacological Chaperones","year":2009,"lang":"en","type":"article","venue":"Traffic","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Computational biology","score_opus":0.010057726538319304,"score_gpt":0.22505428100286554,"score_spread":0.21499655446454624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048117036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99633074,0.00096051133,0.0023422996,0.00008242501,0.000116591524,0.00010243749,0.000009279777,0.000020771635,0.000034961617],"genre_scores_gemma":[0.9989071,0.00048173423,0.0001470591,0.00010943649,0.00017466508,0.000004742228,0.00012744659,0.00000978936,0.000038054393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932796,0.000032767708,0.00016130929,0.00023828955,0.00009265984,0.00014702848],"domain_scores_gemma":[0.9997873,0.000007940781,0.00004825975,0.000064997475,0.000033371747,0.00005813648],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000080912825,0.00011687553,0.00012509376,0.00002610388,0.00006714924,0.000011708487,0.000051726573,0.00011602708,0.000072792725],"category_scores_gemma":[0.00001149879,0.00010328557,0.000051117946,0.000057413108,0.000043311215,0.00000456831,0.00001046116,0.00004753382,0.0000022444258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007456766,0.00007856288,0.000010709023,0.000003772142,0.000019115498,3.6440278e-7,0.00004625189,0.0016191262,0.9549933,0.00004094159,0.0005697858,0.042543475],"study_design_scores_gemma":[0.0004967038,0.0006448914,0.0004694687,0.000006006139,0.000020908468,0.0000059509366,0.00003578888,0.0009961119,0.9960573,0.0000072288685,0.0011333711,0.00012628273],"about_ca_topic_score_codex":5.87677e-7,"about_ca_topic_score_gemma":0.0000011179026,"teacher_disagreement_score":0.04241719,"about_ca_system_score_codex":0.0000065488316,"about_ca_system_score_gemma":0.000020601072,"threshold_uncertainty_score":0.42118633},"labels":[],"label_agreement":null},{"id":"W2048508641","doi":"10.1016/j.brainres.2005.12.052","title":"Antiobesity-like effects of the 5-HT2C receptor agonist WAY-161503","year":2006,"lang":"en","type":"article","venue":"Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Agonist; Receptor; Chinese hamster ovary cell; Partial agonist; Pharmacology; Endocrinology; Inositol phosphate; Chemistry; Receptor antagonist; Internal medicine; Biology; Antagonist; Biochemistry; Inositol; Medicine","score_opus":0.014199168999487238,"score_gpt":0.2936132590090106,"score_spread":0.27941409000952333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048508641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99466664,0.0007996886,0.0005089172,0.00060446427,0.00031809564,0.0003852029,0.000009805476,0.000008531937,0.0026986357],"genre_scores_gemma":[0.9885217,0.00005234759,0.0003647514,0.00011830101,0.00035780497,0.000026233973,0.000034525445,0.000023506307,0.01050083],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983094,0.0003928422,0.00018394167,0.0003071385,0.0004269058,0.0003797904],"domain_scores_gemma":[0.9991158,0.00012391667,0.000052805575,0.00046631,0.00018659892,0.000054531898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009880624,0.00010944912,0.00013078902,0.000056010504,0.00025257748,0.000039992734,0.00042104305,0.00015810085,0.00011321636],"category_scores_gemma":[0.0003166509,0.000080490754,0.00013132844,0.00024399233,0.00020443388,0.0000027870858,0.00025364646,0.00020803655,0.000025251198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026731901,0.00006892976,0.00080267474,0.000063075124,0.000014696482,0.0000016217949,0.000017021857,0.000007351275,0.954157,0.0012004754,0.042361062,0.001279377],"study_design_scores_gemma":[0.00031806334,0.00017773637,0.002421589,0.000035875197,0.0000028440402,0.000002320082,0.000032354015,0.000018825374,0.9068295,0.0005458727,0.08952336,0.000091680675],"about_ca_topic_score_codex":0.00021068566,"about_ca_topic_score_gemma":0.000046259975,"teacher_disagreement_score":0.0473275,"about_ca_system_score_codex":0.00001726762,"about_ca_system_score_gemma":0.00009951424,"threshold_uncertainty_score":0.32823178},"labels":[],"label_agreement":null},{"id":"W2049182645","doi":"10.1016/j.neuroscience.2014.11.017","title":"Regulation of c-fos expression by the dopamine D1-D2 receptor heteromer","year":2014,"lang":"en","type":"article","venue":"Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Nucleus accumbens; Dopamine receptor D2; Dopamine; Neuroscience; Chemistry; Dopamine receptor D1; Biology","score_opus":0.009811758695904173,"score_gpt":0.22944035942854105,"score_spread":0.21962860073263687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049182645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9785087,0.00006245433,0.020595308,0.000111265406,0.00036449157,0.000084013016,0.000004618851,0.000006240858,0.00026291638],"genre_scores_gemma":[0.99851406,0.000023972989,0.00033891926,0.0002711184,0.00007806659,0.000006102383,0.00000875022,0.000007341125,0.00075164734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928147,0.00006844343,0.00012296063,0.0002387233,0.00016638146,0.00012204611],"domain_scores_gemma":[0.9995767,0.000012062544,0.000083991705,0.0002589743,0.000033602133,0.00003465269],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021128761,0.00007046326,0.00006351399,0.000013186858,0.0000931231,0.000017095017,0.00022628087,0.00004543278,0.000038320915],"category_scores_gemma":[0.00011908359,0.000046900714,0.000035745645,0.0000774661,0.00008710734,0.000005265764,0.00006659805,0.000041502808,0.0000028417444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008877309,0.0000125544475,0.00013889455,0.0000025592406,3.0169525e-7,1.8572745e-8,0.000010049679,0.00006677847,0.99611884,0.000039589202,0.0016766705,0.001924869],"study_design_scores_gemma":[0.000094994786,0.00017155941,0.0006867689,0.000006518838,0.0000013610985,0.00000178951,0.0000061192677,0.0005700619,0.9522067,0.000030693845,0.046168666,0.000054817327],"about_ca_topic_score_codex":0.00000350464,"about_ca_topic_score_gemma":4.02333e-7,"teacher_disagreement_score":0.044491995,"about_ca_system_score_codex":0.0000023667935,"about_ca_system_score_gemma":0.000008368078,"threshold_uncertainty_score":0.19125555},"labels":[],"label_agreement":null},{"id":"W2049222500","doi":"10.1016/s0168-1656(02)00008-1","title":"Expression of the human μ opioid receptor in a stable Sf9 cell line","year":2002,"lang":"en","type":"article","venue":"Journal of Biotechnology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina","funders":"","keywords":"Sf9; Transfection; Complementary DNA; Heterologous; Spodoptera; Molecular biology; Heterologous expression; Biology; Cell culture; Signal peptide; Receptor; Cell biology; Gene; Peptide sequence; Recombinant DNA; Biochemistry; Genetics","score_opus":0.010710399725515275,"score_gpt":0.22039317634410377,"score_spread":0.2096827766185885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049222500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99674153,0.0017600964,0.00071379397,0.00036878104,0.00020813046,0.0000654483,0.000003254849,0.0000029711996,0.00013600873],"genre_scores_gemma":[0.99722606,0.0006993257,0.0015571379,0.000047590715,0.000098992314,0.0000012092603,0.0000011793737,0.000010466706,0.00035804318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919564,0.00004800879,0.00038259538,0.00011418771,0.00010921896,0.0001503432],"domain_scores_gemma":[0.99932253,0.0000063262846,0.00036292232,0.00023077955,0.000051037943,0.00002639252],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002115706,0.00008712264,0.00018523124,0.00010571322,0.000039222163,0.00000483239,0.0003458631,0.00034846854,0.00021903127],"category_scores_gemma":[0.000049678525,0.000058858142,0.000105617495,0.00013579591,0.00006531171,0.000003737687,0.00011351608,0.0002680233,0.0000017994314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019248691,0.000101404316,0.00025130322,0.000011230361,0.000006030068,0.0000017766396,0.000039182425,0.000048904432,0.99734277,0.000049189424,0.0013141376,0.0008148444],"study_design_scores_gemma":[0.00049804326,0.0005204347,0.000039035294,0.000054232325,0.0000052328605,0.00001752103,0.00010949344,0.000018149267,0.9858902,0.00017621591,0.012608821,0.00006261881],"about_ca_topic_score_codex":0.000005838382,"about_ca_topic_score_gemma":0.0000058232035,"teacher_disagreement_score":0.011452545,"about_ca_system_score_codex":0.000014132958,"about_ca_system_score_gemma":0.000018804221,"threshold_uncertainty_score":0.26877084},"labels":[],"label_agreement":null},{"id":"W2049443318","doi":"10.1021/bi000597v","title":"Photolabeling Identifies Position 172 of the Human AT<sub>1</sub> Receptor as a Ligand Contact Point:  Receptor-Bound Angiotensin II Adopts an Extended Structure","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Receptor; Ligand (biochemistry); Position (finance); Chemistry; Biophysics; Point (geometry); Stereochemistry; Biochemistry; Biology; Mathematics; Geometry; Business","score_opus":0.00546185144743418,"score_gpt":0.22431052389764017,"score_spread":0.21884867245020598,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049443318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980922,0.00085743,0.000009266479,0.00007820479,0.00026824122,0.00024818224,0.0001686173,0.000029718116,0.0002481539],"genre_scores_gemma":[0.99730414,0.00013540538,0.00019649303,0.00019936413,0.00045877162,0.000010877864,0.0007824522,0.000055155706,0.00085736404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981102,0.000078793135,0.00044974772,0.00066313334,0.00032268892,0.00037549133],"domain_scores_gemma":[0.998668,0.000009100681,0.00025500768,0.0007282444,0.00018708529,0.00015254662],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018419816,0.0003545947,0.00029510373,0.000030243102,0.0005700668,0.00007203548,0.00039395233,0.00050215586,0.0007631994],"category_scores_gemma":[0.00004933971,0.00030819667,0.00025350525,0.00014136138,0.00013451795,0.000017171289,0.00016570637,0.00020914144,0.000011361699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017081763,0.000091017835,0.0000531568,0.00004302969,0.00008687417,0.0000020030134,0.0001687023,0.0000110452,0.99683833,0.000015896097,0.0017018102,0.0008173091],"study_design_scores_gemma":[0.0006368736,0.0002727073,0.00022162823,0.00014193488,0.00004793949,0.000053435175,0.00013373992,0.000013045122,0.9971418,0.00016592513,0.0007909411,0.00038004597],"about_ca_topic_score_codex":0.000037077683,"about_ca_topic_score_gemma":0.000015574007,"teacher_disagreement_score":0.0009108691,"about_ca_system_score_codex":0.00006980941,"about_ca_system_score_gemma":0.00010599006,"threshold_uncertainty_score":0.999937},"labels":[],"label_agreement":null},{"id":"W2049646663","doi":"10.1074/jbc.m808113200","title":"The Second Transmembrane Domain of the Human Type 1 Angiotensin II Receptor Participates in the Formation of the Ligand Binding Pocket and Undergoes Integral Pivoting Movement during the Process of Receptor Activation","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Ligand (biochemistry); Transmembrane domain; Receptor; Domain (mathematical analysis); Biophysics; Transmembrane protein; Cell biology; Process (computing); Angiotensin II; Stereochemistry; Biochemistry; Biology; Computer science; Mathematics","score_opus":0.014478667949027116,"score_gpt":0.2496792648083211,"score_spread":0.23520059685929398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049646663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984732,0.00030813308,0.000023694189,0.0009859925,0.000039355888,0.0001290659,0.000005566143,9.30986e-7,0.000034046177],"genre_scores_gemma":[0.999648,0.00010636177,0.000048677517,0.00008303314,0.00007810405,0.000001902651,0.0000035133594,0.000003522588,0.000026893164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903524,0.00011595354,0.00047038964,0.00008864935,0.00016118925,0.00012860703],"domain_scores_gemma":[0.99907404,0.00006739864,0.0005904279,0.00013489753,0.000115905576,0.000017331124],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007843811,0.0001009509,0.00015704904,0.000010024054,0.00022159242,0.000015792122,0.00031230642,0.00011452772,0.00001846528],"category_scores_gemma":[0.00015975592,0.000036479672,0.000114441915,0.00012806275,0.00013454097,0.000010658159,0.000042470492,0.00020841006,1.9068102e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000117222655,0.000044140266,0.0006221431,0.00004075389,0.000022002427,6.062318e-8,0.00061919726,0.000040986357,0.9982081,0.000022630058,0.000022231707,0.00024054022],"study_design_scores_gemma":[0.0002974628,0.00021806387,0.0025305005,0.00014717554,0.000009982233,0.000006258081,0.002665703,0.000013539397,0.99334884,0.00062108476,0.00009240239,0.00004901832],"about_ca_topic_score_codex":0.0000015721488,"about_ca_topic_score_gemma":0.0000035373075,"teacher_disagreement_score":0.004859282,"about_ca_system_score_codex":0.000014899986,"about_ca_system_score_gemma":0.000027825838,"threshold_uncertainty_score":0.17043321},"labels":[],"label_agreement":null},{"id":"W2049774426","doi":"10.1242/dev.099754","title":"The G protein-coupled receptor GPRC5B contributes to neurogenesis in the developing mouse neocortex","year":2013,"lang":"en","type":"article","venue":"Development","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; University of Illinois at Urbana-Champaign; University of Tokyo; University of Washington","keywords":"Biology; Neurogenesis; Neocortex; Progenitor cell; Neural stem cell; Progenitor; Cell biology; Cell fate determination; Receptor; Signalling; Neuroscience; Signal transduction; Stem cell; Genetics; Transcription factor; Gene","score_opus":0.009206276255415653,"score_gpt":0.2177246699190399,"score_spread":0.20851839366362426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049774426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99026865,0.00025081486,0.0057775024,0.0022719551,0.0001368103,0.0012116327,0.0000010638972,0.000011663222,0.00006992862],"genre_scores_gemma":[0.98604417,0.00006773313,0.008751223,0.0023317565,0.00008728394,0.0014978225,0.00003154761,0.00002865454,0.001159787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987464,0.000088348184,0.00031842315,0.0002945868,0.00018010636,0.00037212146],"domain_scores_gemma":[0.99947125,0.00003132192,0.00006156363,0.0002684806,0.00011318052,0.00005419176],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053284236,0.00016961829,0.0001222743,0.000037644277,0.000292857,0.00013901583,0.0004245497,0.000081580256,0.00004353991],"category_scores_gemma":[0.0001248449,0.00010147661,0.000041873893,0.00017817275,0.000022414699,0.000004318974,0.00013647297,0.00008056979,0.00010829578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021069694,0.000018292856,0.00036533416,0.0000054030243,0.000030012356,8.7886764e-7,0.0002307067,0.000016711523,0.986351,0.00041477213,0.0017073643,0.010838444],"study_design_scores_gemma":[0.00023391999,0.0000414507,0.003983907,0.000017738956,0.0000020641085,0.0000017662269,0.00033870476,0.000028175711,0.808091,0.00008220674,0.18699984,0.00017925176],"about_ca_topic_score_codex":0.00003854292,"about_ca_topic_score_gemma":0.00008194671,"teacher_disagreement_score":0.18529247,"about_ca_system_score_codex":0.000041053183,"about_ca_system_score_gemma":0.00017880075,"threshold_uncertainty_score":0.4138096},"labels":[],"label_agreement":null},{"id":"W2049826872","doi":"10.1016/s0014-4835(03)00032-0","title":"Arrestin migrates in photoreceptors in response to light: a study of arrestin localization using an arrestin-GFP fusion protein in transgenic frogs","year":2003,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; National Institutes of Health; Foundation Fighting Blindness; Research to Prevent Blindness","keywords":"Arrestin; Green fluorescent protein; Visual phototransduction; Cell biology; Biology; Xenopus; Transgene; Fusion protein; Biophysics; Retina; Signal transduction; Neuroscience; Biochemistry; Gene; G protein-coupled receptor","score_opus":0.05649548249226295,"score_gpt":0.3874364315883909,"score_spread":0.330940949096128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049826872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99739236,0.00046250012,0.00016158039,0.000018624845,0.000078005454,0.0018404119,0.0000031849297,0.000007097553,0.000036239533],"genre_scores_gemma":[0.99855477,0.0000067056044,0.0010199867,0.00000972932,0.000034143595,0.00027282385,0.000016686325,0.000042648,0.000042490767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9956942,0.0019943903,0.00056322746,0.00066899403,0.00052905455,0.0005500911],"domain_scores_gemma":[0.9992987,0.00004149905,0.00006357738,0.00034244743,0.00008677562,0.00016699688],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025572071,0.00022354245,0.00028214196,0.00061713485,0.00009103852,0.00003731759,0.0002683715,0.00018072105,0.00011124077],"category_scores_gemma":[0.00042403018,0.00022816574,0.00004393499,0.0010370674,0.000058921058,0.000017887702,0.00009524062,0.00027330333,0.0000040061495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020162268,0.0019540142,0.018608633,0.000015126255,0.000005474741,0.000023072427,0.0052871434,0.0029032764,0.9690549,0.000008628442,0.000005946803,0.00011760866],"study_design_scores_gemma":[0.0019216355,0.0023052185,0.0014438321,0.00018083514,0.0000012264601,0.0000012956076,0.012249941,0.0011800749,0.98031104,0.000024533249,0.00015019039,0.00023016338],"about_ca_topic_score_codex":0.001836599,"about_ca_topic_score_gemma":0.0016842235,"teacher_disagreement_score":0.017164802,"about_ca_system_score_codex":0.00018202647,"about_ca_system_score_gemma":0.00021473467,"threshold_uncertainty_score":0.93043286},"labels":[],"label_agreement":null},{"id":"W2050380620","doi":"10.1074/jbc.m101587200","title":"Cytoplasmic Domain of Natriuretic Peptide Receptor C Constitutes Gi Activator Sequences That Inhibit Adenylyl Cyclase Activity","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Adenylyl cyclase; ADCY10; ADCY9; Peptide; Activator (genetics); ADCY6; Chemistry; NPR2; Peptide sequence; Receptor; Biochemistry; Gs alpha subunit; Molecular biology; Natriuretic peptide; Biology; Internal medicine; Medicine","score_opus":0.022065422808183015,"score_gpt":0.24973781217292784,"score_spread":0.22767238936474482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050380620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970354,0.0008299413,0.0010198823,0.0001508507,0.00016654507,0.000079958016,0.000029136854,0.0000081284,0.00068014883],"genre_scores_gemma":[0.9962873,0.0010000309,0.0019814086,0.0000568095,0.00047147513,0.0000035389692,0.00001808611,0.000012099588,0.00016927466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986018,0.00008853592,0.00046742958,0.00029176957,0.00026053682,0.00028996106],"domain_scores_gemma":[0.9987052,0.00007868205,0.00065714645,0.00019782266,0.00016979202,0.0001913423],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039855402,0.0002449684,0.00044293847,0.00003366234,0.00007603099,0.000025782305,0.00034320002,0.00044641507,0.00052401196],"category_scores_gemma":[0.00032915946,0.00017549715,0.00032547303,0.00011225039,0.00031453307,0.000016316626,0.00009897469,0.00035276057,0.0000033008682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051313086,0.00012710308,0.004108297,0.000033679527,0.00008797546,0.000036190482,0.000013733411,0.000023814871,0.9940536,0.000014589176,0.00044856477,0.0005393362],"study_design_scores_gemma":[0.0006324033,0.000411977,0.00020881652,0.000085756044,0.000020206107,0.00044524032,0.00024282023,0.0000034414045,0.9900359,0.00030079926,0.0073979045,0.00021474864],"about_ca_topic_score_codex":0.0000039520887,"about_ca_topic_score_gemma":6.900168e-7,"teacher_disagreement_score":0.00694934,"about_ca_system_score_codex":0.000044154945,"about_ca_system_score_gemma":0.00017120947,"threshold_uncertainty_score":0.7156566},"labels":[],"label_agreement":null},{"id":"W2050507620","doi":"10.1074/jbc.m112.442053","title":"Structure of the Human Angiotensin II Type 1 (AT1) Receptor Bound to Angiotensin II from Multiple Chemoselective Photoprobe Contacts Reveals a Unique Peptide Binding Mode","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Angiotensin II; Angiotensin II receptor type 1; Chemistry; Peptide; Receptor; Renin–angiotensin system; Angiotensin receptor; Stereochemistry; Biochemistry; Combinatorial chemistry; Endocrinology; Biology","score_opus":0.015119964724435565,"score_gpt":0.24492810865783385,"score_spread":0.2298081439333983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2050507620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99885297,0.00024564858,0.000081810074,0.00025941277,0.00016368435,0.0002522694,0.00007716617,0.000007161231,0.000059904236],"genre_scores_gemma":[0.99535596,0.000033035663,0.0033147098,0.0003305979,0.0005075163,0.0000028333488,0.000071115326,0.000022567367,0.00036164865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984798,0.00008531906,0.0005682358,0.00034067844,0.00020812606,0.00031784538],"domain_scores_gemma":[0.998285,0.00004146621,0.0005677772,0.00030716404,0.00060813397,0.00019046779],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001811798,0.00026933893,0.00046953428,0.000026763833,0.00024499182,0.000031874413,0.0004413335,0.0005145175,0.0004262366],"category_scores_gemma":[0.00047351237,0.00017072422,0.0002957895,0.0001766643,0.00009894868,0.000011250879,0.00029830757,0.00038862266,0.000001795563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013509142,0.000069773836,0.0014841759,0.0000073216697,0.00012544192,0.0000021518767,0.00013331481,0.000034614815,0.99398035,0.0000033374783,0.0039300104,0.0000944473],"study_design_scores_gemma":[0.00048797773,0.0005546939,0.0013690224,0.00011047611,0.00002577931,0.00003317999,0.00013286543,0.000014292123,0.9951691,0.0005044885,0.0013717077,0.00022640824],"about_ca_topic_score_codex":0.0001126982,"about_ca_topic_score_gemma":0.0000088366,"teacher_disagreement_score":0.0034969675,"about_ca_system_score_codex":0.00006779941,"about_ca_system_score_gemma":0.00009765311,"threshold_uncertainty_score":0.69619316},"labels":[],"label_agreement":null},{"id":"W2051002842","doi":"10.1016/j.cellsig.2007.07.015","title":"ARF6 regulates angiotensin II type 1 receptor endocytosis by controlling the recruitment of AP-2 and clathrin","year":2007,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal","funders":"","keywords":"Endocytosis; Clathrin; Cell biology; Receptor-mediated endocytosis; Angiotensin II; Receptor; Chemistry; Biology; Biochemistry","score_opus":0.019830612026644757,"score_gpt":0.2381904973264102,"score_spread":0.21835988529976544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051002842","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9493128,0.016078718,0.033742793,0.000094316216,0.0002203548,0.00038726433,0.000007762986,0.000013741815,0.00014225428],"genre_scores_gemma":[0.9952071,0.000691219,0.0032333524,0.00011778388,0.0002469319,0.0000075846087,0.000077254044,0.000033808097,0.00038501763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986886,0.00006584757,0.00038308685,0.0003535307,0.00018015716,0.00032877305],"domain_scores_gemma":[0.99928623,0.00006335041,0.00018137183,0.00024683552,0.00013057055,0.000091632515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009305665,0.00019886768,0.00024368257,0.000041153304,0.0002257605,0.000026716887,0.00016941737,0.00017897366,0.00005789023],"category_scores_gemma":[0.000044484914,0.00015480876,0.00011714626,0.00011298742,0.00008751154,0.0000048646884,0.00009825834,0.00012660539,0.000002617427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001417485,0.000031231826,0.00006502949,0.000010462686,0.00009026219,0.000001848804,0.00015143692,0.00015644873,0.99544704,0.0002780871,0.00032357097,0.003302827],"study_design_scores_gemma":[0.00044803545,0.00033496716,0.0000062747454,0.000042890642,0.000040539042,0.00000397318,0.00020192089,0.00044738242,0.9667456,0.00012273823,0.031425603,0.00018004091],"about_ca_topic_score_codex":0.000022429605,"about_ca_topic_score_gemma":0.0000036602407,"teacher_disagreement_score":0.045894254,"about_ca_system_score_codex":0.000014371508,"about_ca_system_score_gemma":0.00003243632,"threshold_uncertainty_score":0.6312918},"labels":[],"label_agreement":null},{"id":"W2051146451","doi":"10.1016/j.cellsig.2012.09.021","title":"5-HT1A receptors transactivate the platelet-derived growth factor receptor type beta in neuronal cells","year":2012,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Platelet-derived growth factor receptor; Cell biology; Growth factor receptor; Receptor; Biology; Signal transduction; Transactivation; Receptor tyrosine kinase; Tyrosine phosphorylation; Growth factor; Chemistry; Biochemistry; Transcription factor","score_opus":0.016015212604057125,"score_gpt":0.21265615755260453,"score_spread":0.1966409449485474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051146451","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9843923,0.00157672,0.012159061,0.000081259604,0.0012917304,0.0003046483,0.000011254914,0.000025217738,0.00015784196],"genre_scores_gemma":[0.9973066,0.00041422457,0.00091853,0.00018749908,0.00069779827,0.000017341468,0.0000981899,0.0000752178,0.0002845915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980409,0.0002165381,0.00038370947,0.00042827646,0.0002572307,0.0006733557],"domain_scores_gemma":[0.99927753,0.000054303764,0.00012997669,0.0002776415,0.00007935545,0.00018117267],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041852437,0.00032198825,0.00025571388,0.000070680406,0.00017132127,0.00005323745,0.00038727373,0.0002636588,0.0007805699],"category_scores_gemma":[0.00002886498,0.00025742082,0.0001738333,0.00021919855,0.000065490756,0.000020529169,0.00006114174,0.0003556864,0.00006775616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009599896,0.000068768735,0.00038849714,0.000019029316,0.000046139787,0.0000018345321,0.0003787805,0.00028381837,0.9975541,0.00006116976,0.00017586742,0.00092599005],"study_design_scores_gemma":[0.00036971192,0.00014092049,0.000074842144,0.000024327488,0.0000113622655,0.000002185622,0.00015002687,0.000119416676,0.9821538,0.000029642313,0.016590698,0.00033309378],"about_ca_topic_score_codex":0.000023127035,"about_ca_topic_score_gemma":0.000003483644,"teacher_disagreement_score":0.016414829,"about_ca_system_score_codex":0.00003080202,"about_ca_system_score_gemma":0.00005813566,"threshold_uncertainty_score":0.9999878},"labels":[],"label_agreement":null},{"id":"W2051469767","doi":"10.1016/j.molimm.2009.06.007","title":"C5a- and ASP-mediated C5L2 activation, endocytosis and recycling are lost in S323I-C5L2 mutation","year":2009,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université Laval","funders":"Canada Research Chairs","keywords":"Transfection; Receptor; Cell biology; HEK 293 cells; Internalization; Phosphorylation; Endocytosis; Colocalization; Ligand (biochemistry); Biology; Molecular biology; Biochemistry","score_opus":0.005263659245022652,"score_gpt":0.21787876334925105,"score_spread":0.2126151041042284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051469767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915365,0.0027746176,0.0046718507,0.0005663634,0.00007063676,0.0001799279,0.0000042410943,0.000013661568,0.00018221808],"genre_scores_gemma":[0.9977392,0.00056680024,0.0008574092,0.0006102804,0.000034473705,0.000011657659,0.00011918251,0.000018392755,0.000042595013],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989011,0.00011655763,0.00024857852,0.00039689886,0.00007723177,0.00025959563],"domain_scores_gemma":[0.99955857,0.000021821408,0.00011944671,0.00019250905,0.000062575,0.000045099572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015478679,0.0001741805,0.0002022794,0.0001215092,0.00006793899,0.000030505622,0.00008758774,0.00026458985,0.00002683113],"category_scores_gemma":[0.0001944859,0.00018546707,0.00003746085,0.00012420607,0.000057039244,0.000009910309,0.000055942175,0.00015402271,0.000004801773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007985704,0.000034922905,0.0005052892,0.0000061182295,0.000035728688,0.00002567948,0.000075221724,0.000042187057,0.99158233,0.00020898413,0.000018363466,0.007385311],"study_design_scores_gemma":[0.0011146336,0.00039161014,0.012897887,0.000038043538,0.000013605554,0.00006190091,0.00019759945,0.00014820622,0.9827052,0.00078346935,0.0014092929,0.00023854671],"about_ca_topic_score_codex":0.000020092639,"about_ca_topic_score_gemma":0.000009262084,"teacher_disagreement_score":0.012392598,"about_ca_system_score_codex":0.000019134299,"about_ca_system_score_gemma":0.000026080534,"threshold_uncertainty_score":0.7563128},"labels":[],"label_agreement":null},{"id":"W2051478555","doi":"10.1016/j.schres.2009.07.010","title":"Association study of the gamma-aminobutyric acid type a receptor γ2 subunit gene with schizophrenia","year":2009,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Single-nucleotide polymorphism; Schizophrenia (object-oriented programming); Allele; Genetics; Genetic association; Biology; Genotype; Gene; Medicine; Psychiatry","score_opus":0.02738894331386354,"score_gpt":0.2974281229496194,"score_spread":0.27003917963575585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051478555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980216,0.00046020906,0.000049423696,0.00031275212,0.00018110071,0.0006842203,0.000013634011,0.000016616834,0.00026045833],"genre_scores_gemma":[0.9964937,0.00008976174,0.0011644483,0.000034722452,0.0003691601,0.000028129354,0.000035904726,0.00003227993,0.0017519246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969399,0.00060447806,0.00032267906,0.00050620077,0.0010836927,0.00054307753],"domain_scores_gemma":[0.99809396,0.00004297366,0.00017868147,0.00075614976,0.0008053931,0.00012285846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014434551,0.00021227724,0.0002509992,0.00015022386,0.00035419356,0.00007477218,0.00065374695,0.00021897723,0.0001585155],"category_scores_gemma":[0.00037096418,0.00014592653,0.000091199036,0.0009473334,0.00006602775,0.0000107959795,0.00018701954,0.0005129635,0.000035815345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026332582,0.00036619577,0.003563817,0.000007877465,0.00012894762,0.0000024542499,0.00016301865,0.000049323433,0.9882166,0.000105785686,0.0014149805,0.0033477747],"study_design_scores_gemma":[0.0035849363,0.0048514497,0.01516094,0.000038184826,0.00004581809,0.00000604472,0.00050769234,0.00004724692,0.97337395,0.00026303856,0.0018263365,0.00029437983],"about_ca_topic_score_codex":0.000058227623,"about_ca_topic_score_gemma":0.00013858602,"teacher_disagreement_score":0.014842634,"about_ca_system_score_codex":0.00008264424,"about_ca_system_score_gemma":0.00032383,"threshold_uncertainty_score":0.59507114},"labels":[],"label_agreement":null},{"id":"W2051561558","doi":"10.1074/jbc.m111.318659","title":"High Affinity Neurexin Binding to Cell Adhesion G-protein-coupled Receptor CIRL1/Latrophilin-1 Produces an Intercellular Adhesion Complex","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":180,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute of Mental Health; Howard Hughes Medical Institute","keywords":"Adhesion; Neurexin; Cell adhesion; Intracellular; Chemistry; Cell biology; Intercellular adhesion molecule; Receptor; Intercellular Adhesion Molecule-1; Biophysics; Biochemistry; Biology","score_opus":0.03601087867333218,"score_gpt":0.2585903931827268,"score_spread":0.22257951450939462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051561558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99804157,0.0006569412,0.00055121613,0.00012315449,0.0003523139,0.00018665321,0.00001845888,0.000016842601,0.0000528598],"genre_scores_gemma":[0.9891578,0.00017324841,0.008059815,0.00011685364,0.0021621804,0.0000075814387,0.00014278763,0.00002951547,0.0001502323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979778,0.0001550696,0.00066928775,0.00041290806,0.0002890421,0.00049591943],"domain_scores_gemma":[0.9983997,0.000026237838,0.00048255525,0.00033665553,0.00023051018,0.0005243906],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00089447724,0.00032283078,0.00043802228,0.000052911942,0.00014544795,0.000051028135,0.00052384095,0.00043949185,0.0007417902],"category_scores_gemma":[0.00033381538,0.00023322417,0.0002736514,0.00015163881,0.000059441623,0.000023094446,0.00022727392,0.0003953602,0.00002490433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004690471,0.00032868274,0.00058546796,0.00003904181,0.000023316918,0.000007830948,0.000046932204,0.000027930262,0.99775064,0.00000464894,0.0003100041,0.0004064511],"study_design_scores_gemma":[0.0004829231,0.0013855889,0.00032110032,0.00007528201,0.000018191993,0.000048328107,0.00019387914,0.000011187327,0.99440104,0.000035242334,0.0027115375,0.00031567246],"about_ca_topic_score_codex":0.0000041709677,"about_ca_topic_score_gemma":2.1325037e-7,"teacher_disagreement_score":0.008883773,"about_ca_system_score_codex":0.000050382943,"about_ca_system_score_gemma":0.000042019674,"threshold_uncertainty_score":0.95106053},"labels":[],"label_agreement":null},{"id":"W2051702714","doi":"10.1016/j.bbrc.2006.09.090","title":"Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors","year":2006,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Ministry of Health and Welfare","keywords":"Dopamine receptor D2; Dopamine; Dopaminergic; Dopamine receptor; Receptor; Alternative splicing; Stimulation; G protein-coupled receptor; Chromosomal translocation; Biology; G protein-coupled receptor kinase; Cell biology; Gene isoform; Chemistry; Neuroscience; Gene; Biochemistry","score_opus":0.030479790407140144,"score_gpt":0.2802920784775373,"score_spread":0.24981228807039715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051702714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99872404,0.00050925754,0.00013888249,0.00032682973,0.000013217655,0.00020269735,0.00004261396,0.000002553004,0.000039881426],"genre_scores_gemma":[0.9977867,0.001323497,0.00053658424,0.0000050890235,0.000043793858,0.000011885853,0.000121435885,0.00000809341,0.0001629258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914616,0.00016216496,0.00023057258,0.00017338333,0.00017749198,0.00011024709],"domain_scores_gemma":[0.999084,0.00005820667,0.00012088084,0.00032041798,0.00037702627,0.00003948274],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023190008,0.000082449245,0.00014829173,0.000040274295,0.00009867485,0.00001188477,0.00020526533,0.0000801772,0.000003270943],"category_scores_gemma":[0.00018680243,0.000057324236,0.00002863362,0.00017616323,0.0008136127,0.000008966911,0.00036041476,0.0000965954,1.902898e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007008547,0.00012119702,0.00026573,0.00006203284,0.000017620341,1.5439001e-8,0.000046983743,3.7317514e-7,0.99712515,0.0010327203,0.000014517077,0.0012435637],"study_design_scores_gemma":[0.000201099,0.00014811989,0.0036058177,0.00008424174,0.000009925769,9.2148883e-7,0.00006592645,0.0003630983,0.995043,0.0001357761,0.00027967556,0.00006240399],"about_ca_topic_score_codex":0.00020184151,"about_ca_topic_score_gemma":0.000007746136,"teacher_disagreement_score":0.0033400876,"about_ca_system_score_codex":0.0000058299097,"about_ca_system_score_gemma":0.00003168495,"threshold_uncertainty_score":0.299779},"labels":[],"label_agreement":null},{"id":"W2052064677","doi":"10.1016/j.coph.2014.02.006","title":"Muscarinic acetylcholine receptor X-ray structures: potential implications for drug development","year":2014,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Chemistry; National Institute of Diabetes and Digestive and Kidney Diseases; National Science Foundation; National Institutes of Health; Manning Fund; MDC; National Institute of General Medical Sciences; Sanofi","keywords":"Muscarinic acetylcholine receptor; Muscarinic acetylcholine receptor M5; Muscarinic acetylcholine receptor M2; Muscarinic acetylcholine receptor M4; Muscarinic acetylcholine receptor M3; Muscarinic acetylcholine receptor M1; Pharmacology; Allosteric regulation; Acetylcholine; Chemistry; Receptor; Medicine; Biochemistry","score_opus":0.06871933050258146,"score_gpt":0.41938849633047415,"score_spread":0.3506691658278927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052064677","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000075753545,0.9700109,0.009945685,0.00006937469,0.01792609,0.0017580349,0.00017887042,0.000022840422,0.000012465584],"genre_scores_gemma":[0.000071756884,0.9860831,0.0021733046,0.000043226326,0.003886756,0.0016540876,0.005863834,0.00008362807,0.00014028797],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997232,0.0002842674,0.0009837319,0.0008841925,0.000103162114,0.0005126131],"domain_scores_gemma":[0.9988547,0.0000653557,0.00048171543,0.0003257139,0.00012178421,0.00015075583],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047938805,0.00050698314,0.0009933716,0.00021897693,0.00014775337,0.000027910899,0.0006043918,0.00044598963,0.00033871728],"category_scores_gemma":[0.000042377065,0.00046745338,0.00044112522,0.00015830656,0.00005704473,0.000004414918,0.0002499108,0.00040174442,0.000033673397],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034717097,0.00014157713,0.000002387362,0.007351419,0.00019754688,5.379592e-8,0.000033575467,0.000048489474,0.004128343,0.00022865449,0.06566554,0.9221677],"study_design_scores_gemma":[0.0008413729,0.00006112393,0.0000024547192,0.00075511704,0.0001277829,0.000006096625,0.0000039947836,0.000013926833,0.0007147722,0.00004997816,0.99694455,0.00047886002],"about_ca_topic_score_codex":9.699334e-7,"about_ca_topic_score_gemma":7.921303e-7,"teacher_disagreement_score":0.931279,"about_ca_system_score_codex":0.00010155519,"about_ca_system_score_gemma":0.00054768054,"threshold_uncertainty_score":0.99977773},"labels":[],"label_agreement":null},{"id":"W2052102717","doi":"10.1096/fj.14-254037","title":"A peptide targeting an interaction interface disrupts the dopamine D1‐D2 receptor heteromer to block signaling and function <i>in vitro</i> and <i>in vivo:</i> effective selective antagonism","year":2014,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; National Institutes of Health","keywords":"Dopamine receptor D2; 5-HT5A receptor; Dopamine receptor D1; Receptor; G protein-coupled receptor; Nuclear receptor co-repressor 1; Chemistry; Pharmacology; Biology; Biochemistry; Nuclear receptor; Gene","score_opus":0.005415006860134739,"score_gpt":0.23450393765288893,"score_spread":0.2290889307927542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052102717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99111724,0.00031261737,0.007687068,0.00020076976,0.0003246973,0.00029836845,0.000005438351,0.0000060648676,0.0000477181],"genre_scores_gemma":[0.99865395,0.000083540064,0.00035932704,0.0003358485,0.00047039465,0.000023013397,0.000006559758,0.000024631094,0.000042752486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985155,0.0005000758,0.00027080442,0.00030781617,0.0001263454,0.00027944474],"domain_scores_gemma":[0.9994671,0.00009672029,0.00014182288,0.00012777856,0.000063050386,0.0001035746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012820691,0.00019231676,0.00018268007,0.00007377454,0.00026199577,0.0001334004,0.00012795834,0.00008029063,0.0000116587635],"category_scores_gemma":[0.00009660096,0.00012394485,0.000050248804,0.00011244429,0.000045649045,0.000029606812,0.00008647816,0.00040260926,0.0000018124583],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088063325,0.000030405325,0.00031393577,0.000006014844,0.000029293382,0.0000013542045,0.0007111976,0.0013641882,0.99263036,0.0000029013345,0.00006312782,0.0039665764],"study_design_scores_gemma":[0.000634384,0.0007367653,0.00020411548,0.000058224425,0.000021173437,0.00012847294,0.0012660243,0.0013580504,0.9941051,0.00007085187,0.0012517076,0.0001651274],"about_ca_topic_score_codex":0.000044426954,"about_ca_topic_score_gemma":0.000043818043,"teacher_disagreement_score":0.0075366753,"about_ca_system_score_codex":0.000042750566,"about_ca_system_score_gemma":0.000014630992,"threshold_uncertainty_score":0.5054324},"labels":[],"label_agreement":null},{"id":"W2053001938","doi":"10.1371/journal.pone.0042791","title":"Simultaneous Detection of Ca2+ and Diacylglycerol Signaling in Living Cells","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alberta Innovates","keywords":"Diacylglycerol kinase; Second messenger system; Intracellular; Inositol; Phospholipase C; Cell biology; Phospholipase; Phosphoinositide phospholipase C; Fluorescence; Calcium; Biology; Biophysics; Biochemistry; Chemistry; Signal transduction; Protein kinase C; Receptor; Enzyme","score_opus":0.014263951753504358,"score_gpt":0.20211981133532972,"score_spread":0.18785585958182535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053001938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99778354,0.0010660401,0.0009537047,0.000002724518,0.000035661455,0.00009579705,0.0000023013313,0.0000048213587,0.000055402044],"genre_scores_gemma":[0.9984691,0.00012714561,0.0011771632,0.000018961893,0.0001363861,0.000006486132,0.0000025360655,0.000013105413,0.000049078455],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994562,0.000037282047,0.00013678291,0.00012027548,0.00008620637,0.00016322632],"domain_scores_gemma":[0.9997309,0.00004884507,0.0000523974,0.00008856492,0.000029822882,0.00004948636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017822607,0.00007254112,0.000117454285,0.000033692806,0.000024561527,0.0000064538567,0.000039482056,0.0000857254,0.000025904483],"category_scores_gemma":[0.00010167838,0.00007445832,0.000022453232,0.000042225667,0.0000145611375,0.000004073017,0.000039070506,0.000055576063,0.0000019217696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018748788,0.00019432862,0.0025262018,0.000043622,0.00003207224,4.068784e-7,0.00017430537,0.00010187805,0.9959712,0.0000024345668,3.5840057e-7,0.000934466],"study_design_scores_gemma":[0.00011264767,0.00012211404,0.00015840374,0.0000691757,0.000023536844,9.335733e-7,0.00007855032,0.0006894877,0.99863553,0.00000690892,0.000017540271,0.00008517812],"about_ca_topic_score_codex":0.000023886774,"about_ca_topic_score_gemma":0.000010083767,"teacher_disagreement_score":0.0026643458,"about_ca_system_score_codex":0.000007022038,"about_ca_system_score_gemma":0.0000065571926,"threshold_uncertainty_score":0.30363223},"labels":[],"label_agreement":null},{"id":"W2053066866","doi":"10.1016/s0169-328x(99)00343-5","title":"New dopamine receptor, D2Longer, with unique TG splice site, in human brain","year":2000,"lang":"en","type":"article","venue":"Molecular Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dopamine receptor D2; Dopamine receptor D3; Dopamine; Biology; Dopamine receptor; Dopamine receptor D1; Antipsychotic; Receptor; Psychosis; Pharmacology; Neuroscience; Schizophrenia (object-oriented programming); Internal medicine; Psychology; Medicine; Genetics; Psychiatry","score_opus":0.018188377906233913,"score_gpt":0.32075631105487473,"score_spread":0.30256793314864083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053066866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98549825,0.0008222419,0.0041944785,0.0022126825,0.000027231525,0.0005595833,0.000009164607,0.000026881247,0.006649459],"genre_scores_gemma":[0.95607704,0.00018281453,0.0067203534,0.0013732048,0.00033142528,0.00010567067,0.0004269492,0.00015062706,0.034631934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99672866,0.00062034966,0.00031786106,0.0008327422,0.0006526596,0.0008477205],"domain_scores_gemma":[0.99867177,0.000070008304,0.000042266714,0.00075096224,0.00015828136,0.0003067222],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016118578,0.00027855835,0.0002555304,0.00024252468,0.0001838008,0.00008331423,0.0005125309,0.00029854322,0.0024659536],"category_scores_gemma":[0.00016319791,0.00026307954,0.000096531854,0.0007010381,0.00012470021,0.000010218507,0.0001576619,0.00055034505,0.00009736826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019383324,0.00008346276,0.00019653652,0.00001954206,0.000031213294,0.000108633496,0.00012730066,0.00019782047,0.97352093,0.00045220903,0.015032924,0.010035584],"study_design_scores_gemma":[0.0013922836,0.0010452662,0.00022416394,0.00007507401,0.0000034304417,0.000026620955,0.00008601304,0.000054361037,0.8726171,0.0004237892,0.123667,0.0003848631],"about_ca_topic_score_codex":0.00085096783,"about_ca_topic_score_gemma":0.0004096999,"teacher_disagreement_score":0.10863408,"about_ca_system_score_codex":0.000059115766,"about_ca_system_score_gemma":0.00024952553,"threshold_uncertainty_score":0.9999821},"labels":[],"label_agreement":null},{"id":"W2053415823","doi":"10.1080/10799890801941962","title":"Meeting Review: Advances from the GPCR Retreat","year":2008,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University; Western University","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec","keywords":"Attendance; G protein-coupled receptor; Club; Library science; Geography; Medicine; Political science; Computer science","score_opus":0.01135979478171353,"score_gpt":0.22908877096402938,"score_spread":0.21772897618231585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053415823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8113968,0.18119328,0.0056019644,0.00073246204,0.000780827,0.00010763426,0.000006349916,0.000004303454,0.00017637236],"genre_scores_gemma":[0.709542,0.2869235,0.0015896452,0.00031922164,0.0014477923,0.000002233992,0.000014098214,0.000015102554,0.00014639918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909854,0.00010915205,0.00033731584,0.00014215075,0.00019926389,0.00011358683],"domain_scores_gemma":[0.9994699,0.000029066125,0.00022530432,0.00008386319,0.00012680252,0.00006509066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003958187,0.0001155534,0.0001945392,0.000020994099,0.00018252658,0.0000129003065,0.00010799316,0.00007325059,0.00026675884],"category_scores_gemma":[0.000040613668,0.00007224672,0.00015403665,0.000071156115,0.00006649279,0.000018914407,0.000009129861,0.00015135329,9.165325e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017468158,0.000044888377,0.0015217225,0.00004917859,0.00010133306,0.000006399724,0.0002630324,0.000095290394,0.9460487,0.000012589101,0.009460382,0.042221814],"study_design_scores_gemma":[0.00061490416,0.00077669055,0.00030695274,0.0006674786,0.00011650925,0.0004390554,0.00039955662,0.000018581297,0.5619277,0.0002078465,0.4343056,0.0002191712],"about_ca_topic_score_codex":0.000012000651,"about_ca_topic_score_gemma":0.000003296294,"teacher_disagreement_score":0.42484522,"about_ca_system_score_codex":0.000008173232,"about_ca_system_score_gemma":0.000033171065,"threshold_uncertainty_score":0.29461357},"labels":[],"label_agreement":null},{"id":"W2053578474","doi":"10.1139/cjpp-78-1-7","title":"Dopamine D&lt;sub&gt;3&lt;/sub&gt; receptor binding by D&lt;sub&gt;3&lt;/sub&gt; agonist 7-OH-DPAT (7-hydroxy-dipropylaminotetralin) and antipsychotic drugs measured ex vivo by quantitative autoradiography","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Pharmacology; Dopamine receptor D3; Agonist; Chemistry; Antipsychotic; Ex vivo; Dopamine; Dopamine receptor D2; Nucleus accumbens; Receptor; Internal medicine; Medicine; Biochemistry; In vitro; Schizophrenia (object-oriented programming)","score_opus":0.008910308039351573,"score_gpt":0.2378692161303741,"score_spread":0.2289589080910225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053578474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97111994,0.024314597,0.00016137633,0.00067669014,0.0022367209,0.0005389035,0.00075742387,0.000026862766,0.00016750062],"genre_scores_gemma":[0.98456895,0.012126108,0.00036036575,0.0010960446,0.000944487,0.000032560005,0.00042693136,0.00012731078,0.00031724045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.994744,0.00095552724,0.0012240948,0.0012090208,0.0003399567,0.0015274169],"domain_scores_gemma":[0.9967176,0.00018438914,0.00080246385,0.00037775378,0.00041619714,0.0015016012],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010119306,0.0009251574,0.0013174486,0.00061187777,0.00086036243,0.00012425112,0.0006889399,0.00097234,0.0016323683],"category_scores_gemma":[0.000073248426,0.0009108128,0.00047549114,0.00056206953,0.0011679236,0.00009296583,0.00006752551,0.0009194227,0.000041930052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009726247,0.0001601772,0.00014516499,0.00010842614,0.00089644606,0.00008228508,0.0003857783,0.00007485322,0.9451134,0.00009535151,0.048909724,0.0030557322],"study_design_scores_gemma":[0.0035067196,0.0021260006,0.00025507188,0.000091167785,0.00036784838,0.0002482463,0.00009406217,0.00022296332,0.8995063,0.00025140998,0.0923655,0.00096472766],"about_ca_topic_score_codex":0.0001235688,"about_ca_topic_score_gemma":0.0004591365,"teacher_disagreement_score":0.045607157,"about_ca_system_score_codex":0.00013998254,"about_ca_system_score_gemma":0.0006277833,"threshold_uncertainty_score":0.9993343},"labels":[],"label_agreement":null},{"id":"W2053777069","doi":"10.1016/j.bmc.2010.03.064","title":"Selective angiotensin II AT2 receptor agonists with reduced CYP 450 inhibition","year":2010,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Chemistry; Agonist; Stereochemistry; Moiety; Chemical synthesis; Receptor; Structure–activity relationship; Enzyme; Pharmacology; Biochemistry; In vitro","score_opus":0.00460061864108225,"score_gpt":0.2076819094055158,"score_spread":0.20308129076443357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053777069","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969087,0.00024043658,0.00035888856,0.00054748735,0.00032341978,0.00017284795,0.000018883364,0.00005385524,0.0013754579],"genre_scores_gemma":[0.99434304,0.000046018627,0.0016566654,0.00025103803,0.0017309984,0.000017600498,0.00032436094,0.000060381317,0.0015699228],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983285,0.00002455274,0.00027430494,0.00063467846,0.0003223454,0.0004156369],"domain_scores_gemma":[0.99890476,0.000008761195,0.00016409821,0.00042545202,0.00024661465,0.0002502814],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024620586,0.0003174416,0.0002599795,0.000026702623,0.0002548553,0.000027749044,0.00018921339,0.00044564548,0.0008148443],"category_scores_gemma":[0.00015072018,0.00026897015,0.00009506367,0.00020419173,0.00017762453,0.0000074463887,0.0001011324,0.00045587195,0.000019377201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017550049,0.000080452526,0.00006090881,0.000026739588,0.00006539633,0.0000101866535,0.00009496146,4.1452273e-7,0.99470013,0.000011342049,0.004141297,0.0006326902],"study_design_scores_gemma":[0.00081183494,0.00041085877,0.00020647827,0.00006438477,0.000043169995,0.0002141779,0.0001561933,0.000007405104,0.9842727,0.000027456572,0.013428307,0.0003569899],"about_ca_topic_score_codex":0.000029319568,"about_ca_topic_score_gemma":0.000013334928,"teacher_disagreement_score":0.010427367,"about_ca_system_score_codex":0.000041755062,"about_ca_system_score_gemma":0.00029333844,"threshold_uncertainty_score":0.9999763},"labels":[],"label_agreement":null},{"id":"W2053845129","doi":"10.1385/mb:34:1:1","title":"Molecular Characterization of Dopamine D2 Receptor Isoforms Tagged With Green Fluorescent Protein","year":2006,"lang":"en","type":"article","venue":"Molecular Biotechnology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Health Canada","funders":"","keywords":"Green fluorescent protein; Receptor; HEK 293 cells; Cell biology; Transfection; Biology; Gene isoform; Dopamine; Molecular biology; Chemistry; Biochemistry; Endocrinology; Gene","score_opus":0.0025543016646135766,"score_gpt":0.1775962293246496,"score_spread":0.17504192766003604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053845129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8299111,0.00019024538,0.16866982,0.0005147989,0.000049653227,0.0005223595,0.00002213188,0.000061651845,0.0000582159],"genre_scores_gemma":[0.99301046,0.000030378545,0.0057353103,0.000100010184,0.00006277597,0.00008008315,0.0006516989,0.0000724168,0.00025687565],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983281,0.000060550243,0.00039615354,0.00056218955,0.00024300459,0.00041001028],"domain_scores_gemma":[0.9989252,0.0000018640418,0.0002629004,0.0006107646,0.00014276024,0.00005648499],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001416833,0.00030538955,0.00031024008,0.00017989278,0.00006392436,0.000016774808,0.00034022823,0.0005816992,0.000047064794],"category_scores_gemma":[0.000023663391,0.00026531966,0.000118113865,0.00031889233,0.0001868305,0.0000065290665,0.00015067213,0.00017907128,0.0000096454005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013146715,0.000120723715,0.00009014553,0.00003915409,0.000062915424,0.000018655663,0.00000459596,0.00005077613,0.99308735,0.0026677034,0.000012618855,0.0037139219],"study_design_scores_gemma":[0.00074384396,0.000905563,0.00008304631,0.000044457614,0.000023666713,0.000024435614,0.000014432216,0.000086963,0.990019,0.00015843894,0.007566165,0.00032995897],"about_ca_topic_score_codex":0.00010196015,"about_ca_topic_score_gemma":0.000014677702,"teacher_disagreement_score":0.16309933,"about_ca_system_score_codex":0.000024344205,"about_ca_system_score_gemma":0.000061534876,"threshold_uncertainty_score":0.9999799},"labels":[],"label_agreement":null},{"id":"W2053911700","doi":"10.1074/jbc.m707941200","title":"Bioluminescence Resonance Energy Transfer Assays Reveal Ligand-specific Conformational Changes within Preformed Signaling Complexes Containing δ-Opioid Receptors and Heterotrimeric G Proteins","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal; Institut universitaire en santé mentale de Montréal","funders":"National Institute on Drug Abuse","keywords":"Heterotrimeric G protein; Bioluminescence; Chemistry; Förster resonance energy transfer; G protein-coupled receptor; Energy transfer; Receptor; Cell biology; G protein; Biophysics; Ligand (biochemistry); Biochemistry; Biology; Physics; Fluorescence","score_opus":0.028980538751834976,"score_gpt":0.226611963430311,"score_spread":0.19763142467847603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053911700","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914504,0.003819366,0.004323278,0.00006566593,0.0001247829,0.00009954721,0.000016770475,0.000010797507,0.000089356385],"genre_scores_gemma":[0.9944445,0.0022175275,0.002414388,0.0001520728,0.0005782557,0.0000132382165,0.000059189293,0.000014370236,0.000106488296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855286,0.0000616831,0.0005942336,0.00027603479,0.000233788,0.00028140715],"domain_scores_gemma":[0.9991486,0.000038927945,0.00031045015,0.00012110045,0.00021270388,0.00016823062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003910686,0.00024234502,0.00037907914,0.00003388866,0.00019147429,0.000029610528,0.00023208582,0.00029614195,0.00006249697],"category_scores_gemma":[0.000091586975,0.00017581346,0.00013103907,0.000094991585,0.00024224291,0.000016545551,0.000054989992,0.00023849795,5.595819e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003978234,0.000043543827,0.0008226684,0.000026515447,0.00003559629,0.000012461656,0.00013011043,0.00001330838,0.99728525,0.000026769685,0.00012874372,0.0010772386],"study_design_scores_gemma":[0.00070862676,0.00081423024,0.00030606403,0.000108302804,0.0000072050993,0.0005192923,0.00018522725,0.00002359126,0.9877217,0.000050413328,0.009310377,0.00024496042],"about_ca_topic_score_codex":0.000004377658,"about_ca_topic_score_gemma":6.7740444e-7,"teacher_disagreement_score":0.00956351,"about_ca_system_score_codex":0.000028139897,"about_ca_system_score_gemma":0.0000888859,"threshold_uncertainty_score":0.7169465},"labels":[],"label_agreement":null},{"id":"W2053941511","doi":"10.1038/nm.2315","title":"Schizophrenia susceptibility pathway neuregulin 1–ErbB4 suppresses Src upregulation of NMDA receptors","year":2011,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Neuregulin 1; ERBB4; NMDA receptor; ErbB; Long-term potentiation; Neuroscience; Hippocampal formation; Proto-oncogene tyrosine-protein kinase Src; Hippocampus; Neuregulin; Schaffer collateral; Signal transduction; Glutamate receptor; Receptor tyrosine kinase; Receptor; Medicine; Cell biology; Biology; Internal medicine","score_opus":0.01330076220221212,"score_gpt":0.23950645485092284,"score_spread":0.2262056926487107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053941511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933376,0.0021148517,0.0013904977,0.00016936651,0.0011537125,0.00023431036,0.000013181614,0.0000244736,0.0015620322],"genre_scores_gemma":[0.9957123,0.00009436357,0.002592049,0.00014509096,0.00086684414,0.000007338228,0.00018748123,0.000025646626,0.00036891355],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863577,0.00009942514,0.0003582363,0.000415634,0.00027765517,0.00021325354],"domain_scores_gemma":[0.99898976,0.00002231954,0.00018140241,0.00047511377,0.00022748882,0.000103911276],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00042595473,0.00020451067,0.00028194088,0.00006799868,0.00005448677,0.0000036994336,0.00024237939,0.0005074631,0.0012372022],"category_scores_gemma":[0.00034346597,0.00015576016,0.00009444932,0.00015746814,0.00015991963,0.0000066474972,0.00006707573,0.00029478504,0.0000037482826],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033663405,0.000058813454,0.0011780395,0.000043106178,0.00003444349,0.0000011067845,0.0002164881,0.000005722131,0.9895948,0.0005946961,0.0026321646,0.0053039803],"study_design_scores_gemma":[0.0008345176,0.0006232264,0.0035325082,0.00006445913,0.000024592955,0.000004378684,0.00012247649,0.00002064743,0.9829341,0.000791622,0.010890039,0.0001574259],"about_ca_topic_score_codex":0.000046078985,"about_ca_topic_score_gemma":0.000037991504,"teacher_disagreement_score":0.008257873,"about_ca_system_score_codex":0.000010010779,"about_ca_system_score_gemma":0.00005543861,"threshold_uncertainty_score":0.9996758},"labels":[],"label_agreement":null},{"id":"W2053963685","doi":"10.1016/j.bcp.2010.06.004","title":"Temperature dependent photolabeling of the human angiotensin II type 1 receptor reveals insights into its conformational landscape and its activation mechanism","year":2010,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Mechanism (biology); Chemistry; Biophysics; Receptor; Angiotensin II; Stereochemistry; Biology; Biochemistry; Physics","score_opus":0.008696802367561558,"score_gpt":0.25899184175253404,"score_spread":0.2502950393849725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053963685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99808186,0.00062910723,0.000015160633,0.00025790907,0.00067823916,0.00026832774,0.000009750623,0.000009883204,0.000049768925],"genre_scores_gemma":[0.99840605,0.000079912716,0.0002822886,0.0005535189,0.0003828687,0.0000133817675,0.00011535739,0.0000151942195,0.00015140405],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991332,0.000052765397,0.0002513466,0.00025742312,0.00014089044,0.00016434678],"domain_scores_gemma":[0.99936754,0.000016442116,0.00014817883,0.000121620265,0.00026749066,0.00007875722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014757863,0.00015152931,0.00015752917,0.000039231705,0.00021005787,0.000011481439,0.00018908798,0.0003718588,0.0003201149],"category_scores_gemma":[0.00006996529,0.00011556116,0.000054343705,0.00009394103,0.00004283093,0.000010384106,0.00019984636,0.00027258176,0.000003256241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057182973,0.00004132373,0.000013018701,0.000020776512,0.000044657078,2.0237346e-7,0.000117734875,0.0000031945315,0.9916874,0.00084758864,0.007150547,0.000016346714],"study_design_scores_gemma":[0.00056506187,0.00010962671,0.000037796577,0.000013665995,0.000024387762,0.0000073728256,0.000027180082,0.00012938405,0.996323,0.0002688395,0.002354021,0.00013968365],"about_ca_topic_score_codex":0.000002394216,"about_ca_topic_score_gemma":7.8968503e-7,"teacher_disagreement_score":0.0047965264,"about_ca_system_score_codex":0.00000893234,"about_ca_system_score_gemma":0.000057256104,"threshold_uncertainty_score":0.47124475},"labels":[],"label_agreement":null},{"id":"W2054172569","doi":"10.1016/j.bbrc.2014.02.033","title":"CHIP-MYTH: A novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β2-adrenergic receptor","year":2014,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Princess Margaret Cancer Centre; University of Toronto; University Health Network; Mount Sinai Hospital; Lunenfeld-Tanenbaum Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Austrian Science Fund; Ontario Genomics Institute; Cystic Fibrosis Foundation; University Health Network; Canadian Institutes of Health Research; Ontario Genomics","keywords":"Interactome; G protein-coupled receptor; Heterotrimeric G protein; Computational biology; Receptor; Cell biology; Signal transduction; Bioinformatics; Chemistry; Biology; Pharmacology; G protein; Biochemistry; Gene","score_opus":0.07141066383452006,"score_gpt":0.425539785278488,"score_spread":0.35412912144396796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054172569","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8496317,0.00030321124,0.14120027,0.0056128553,0.00015110572,0.0017864858,0.00035677667,0.000011798689,0.0009457532],"genre_scores_gemma":[0.9690768,0.00010646447,0.030132115,0.000045788263,0.0001151238,0.00025644878,0.00009723056,0.000012513007,0.00015748043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987912,0.00028484146,0.00027328683,0.00022873013,0.00023848137,0.00018347072],"domain_scores_gemma":[0.9977646,0.0006408872,0.00014416158,0.0009537383,0.00043355176,0.00006306373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00083765754,0.00010640858,0.00016408741,0.000032424832,0.00041750426,0.000034164932,0.00089569844,0.0000837474,0.000011020535],"category_scores_gemma":[0.00041999915,0.00006325344,0.0001404459,0.00014694477,0.0005150295,0.0000055382025,0.0007598077,0.00034930176,4.479632e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030578474,0.00031795487,0.0000138307205,0.000023048276,0.00006466678,3.1019787e-9,0.00004027789,0.0000056623294,0.9797062,0.018294899,0.00029144163,0.0012114078],"study_design_scores_gemma":[0.00029244254,0.0002278997,0.00021752385,0.000039912728,0.000025542637,0.0000010382358,0.00015580918,0.0055894926,0.982879,0.00089072384,0.009601824,0.000078788464],"about_ca_topic_score_codex":0.0001239397,"about_ca_topic_score_gemma":0.000015052489,"teacher_disagreement_score":0.11944509,"about_ca_system_score_codex":0.000023570894,"about_ca_system_score_gemma":0.00008368551,"threshold_uncertainty_score":0.32111475},"labels":[],"label_agreement":null},{"id":"W2054295839","doi":"10.1016/j.cellsig.2005.05.004","title":"RGS2 interacts with Gs and adenylyl cyclase in living cells","year":2005,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Montreal Heart Institute; Western University","funders":"","keywords":"RGS2; Adenylyl cyclase; Heterotrimeric G protein; Gs alpha subunit; G protein; HEK 293 cells; Green fluorescent protein; Cell biology; Molecular biology; Luciferase; Signal transduction; Chemistry; Biology; Transfection; Receptor; GTPase-activating protein; Biochemistry; Gene","score_opus":0.00497292064144097,"score_gpt":0.1929155418559729,"score_spread":0.18794262121453192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054295839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97065943,0.0018926521,0.026827304,0.000036869107,0.000065447566,0.00012688596,0.0000015144577,0.00001265545,0.00037723355],"genre_scores_gemma":[0.99390054,0.00015499552,0.0050379056,0.00015563512,0.00029312161,0.000009422928,0.00001529741,0.00003534479,0.00039772535],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989345,0.000050349223,0.00021674854,0.00038775883,0.00011799332,0.00029263334],"domain_scores_gemma":[0.9995999,0.000029210436,0.00007035217,0.00015899247,0.000034869634,0.00010668352],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002634965,0.00018310202,0.00016084031,0.00006990964,0.00006698926,0.000062269166,0.00012240387,0.00012303819,0.00012450072],"category_scores_gemma":[0.000019669422,0.00016728515,0.00004411442,0.000073926945,0.000032233103,0.0000113583155,0.000075467484,0.0001557219,0.000012524366],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031114127,0.00003914764,0.00036508686,0.000018051625,0.000016949847,0.000018161365,0.00024317914,0.0029602929,0.99420357,0.00003299924,0.000026419228,0.002045013],"study_design_scores_gemma":[0.00031300893,0.00014874697,0.000036380734,0.00015646654,0.000011759293,0.000011284109,0.00018924449,0.003032946,0.99277073,0.000015989463,0.0030678546,0.00024557262],"about_ca_topic_score_codex":0.000016404936,"about_ca_topic_score_gemma":0.000047253638,"teacher_disagreement_score":0.023241114,"about_ca_system_score_codex":0.000016519498,"about_ca_system_score_gemma":0.000032161133,"threshold_uncertainty_score":0.6821691},"labels":[],"label_agreement":null},{"id":"W2054656938","doi":"10.1074/jbc.m105572200","title":"Different Subtypes of α1-Adrenoceptor Modulate Different K+ Currents via Different Signaling Pathways in Canine Ventricular Myocytes","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Heart And Stroke Foundation Of Quebec; Heart and Stroke Foundation of Canada","keywords":"Myocyte; Signal transduction; Internal medicine; Beta adrenoceptor; Chemistry; Adrenergic receptor; Endocrinology; Cell biology; Pharmacology; Biology; Medicine; Receptor","score_opus":0.01896233339462368,"score_gpt":0.23178838984566788,"score_spread":0.2128260564510442,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054656938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947792,0.0029579524,0.001834582,0.000030487665,0.00023097952,0.00011035483,0.000019192128,0.0000070241454,0.000030206365],"genre_scores_gemma":[0.99807525,0.001182255,0.00010966459,0.000025302272,0.0004690876,0.0000063190173,0.000076729775,0.00002065476,0.00003475912],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99785906,0.00010001966,0.00093828625,0.0003590872,0.0003284336,0.00041513058],"domain_scores_gemma":[0.9987208,0.000045629666,0.00062186125,0.00022861439,0.00016508509,0.00021797897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022833943,0.00037085093,0.00069903064,0.000062430525,0.000050110553,0.000021576581,0.0004108538,0.00036365225,0.000541518],"category_scores_gemma":[0.00012230236,0.00023711855,0.00040914209,0.000109787325,0.00007958805,0.000007007906,0.0001573024,0.0003594539,0.0000010095333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000250732,0.0005214451,0.048994333,0.00005449443,0.000094744355,0.000051762443,0.000022584112,0.0002797676,0.9483874,0.000004040926,0.000023666395,0.0013150646],"study_design_scores_gemma":[0.0011532535,0.0005800394,0.009978363,0.00015147186,0.000035456098,0.00010722198,0.00007090509,0.00024450873,0.9869725,0.00028153273,0.00014518971,0.0002795545],"about_ca_topic_score_codex":0.0000060390857,"about_ca_topic_score_gemma":0.0000018181177,"teacher_disagreement_score":0.039015967,"about_ca_system_score_codex":0.000074383126,"about_ca_system_score_gemma":0.000032255946,"threshold_uncertainty_score":0.9669414},"labels":[],"label_agreement":null},{"id":"W2054922477","doi":"10.1016/j.cellsig.2005.02.008","title":"Oligomerization of the α and β isoforms of the thromboxane A2 receptor: Relevance to receptor signaling and endocytosis","year":2005,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Endocytosis; Gene isoform; Cell biology; Receptor; Signal transduction; Receptor-mediated endocytosis; Thromboxane receptor; Relevance (law); Thromboxane A2; Chemistry; Biology; Biochemistry; Political science","score_opus":0.007895704898155123,"score_gpt":0.2062874810711068,"score_spread":0.19839177617295167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054922477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9818277,0.0018827745,0.015565738,0.00019303347,0.00016177077,0.00029036563,0.000012580576,0.0000060332295,0.000059998143],"genre_scores_gemma":[0.994174,0.00048440468,0.0048515196,0.00012967677,0.00017323362,0.000009455529,0.000008879148,0.000026494869,0.00014235947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988676,0.000076325276,0.00035208938,0.00030006014,0.00020321118,0.00020075806],"domain_scores_gemma":[0.9993004,0.000034819528,0.00022342235,0.00028220666,0.00009498058,0.000064167805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031279773,0.00016289213,0.00020890943,0.000031556694,0.00015913948,0.000019718076,0.00024201749,0.00011783859,0.000056756537],"category_scores_gemma":[0.000105826,0.00010818134,0.00009954649,0.0001711662,0.000101089296,0.000010220056,0.00017915647,0.00010303072,0.0000014459979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026020818,0.000018279965,0.0005028738,0.0000421579,0.000030953535,3.8110226e-8,0.00029787238,0.0016425293,0.99520284,0.00018855542,0.000020952355,0.0020269395],"study_design_scores_gemma":[0.00021633154,0.0001003434,0.00006466462,0.00013025859,0.00002546829,0.0000013092366,0.00014855972,0.0003468978,0.9951325,0.00007552565,0.0036199254,0.00013823574],"about_ca_topic_score_codex":0.00001097116,"about_ca_topic_score_gemma":0.0000048959273,"teacher_disagreement_score":0.0123462705,"about_ca_system_score_codex":0.000010632059,"about_ca_system_score_gemma":0.000038714614,"threshold_uncertainty_score":0.4411507},"labels":[],"label_agreement":null},{"id":"W2055001682","doi":"10.1016/j.schres.2011.06.004","title":"Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: An animal model","year":2011,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Canada Research Chairs; University of Toronto","funders":"","keywords":"Endocrinology; Internal medicine; Raclopride; Ketanserin; Serotonergic; Histaminergic; Insulin; Chemistry; Ritanserin; Antagonist; Pharmacology; Receptor; Serotonin; Medicine; 5-HT receptor","score_opus":0.04403911693280673,"score_gpt":0.306368559421382,"score_spread":0.2623294424885753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055001682","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988807,0.00034610383,0.00014822235,0.000016844519,0.00006420806,0.00037314987,0.00001586452,0.000009867994,0.00014507164],"genre_scores_gemma":[0.995303,0.00064856326,0.0037279238,0.000013745986,0.00009186671,0.000035630994,0.00003382688,0.00003530659,0.00011016541],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981285,0.00027296753,0.00029031237,0.0005784483,0.0003365617,0.00039322855],"domain_scores_gemma":[0.99925834,0.00005035675,0.00006673286,0.00031575238,0.00011793985,0.00019086519],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082971936,0.00019475067,0.00024545728,0.0002841053,0.000098438635,0.00002821705,0.00019190757,0.00029915856,0.0000374799],"category_scores_gemma":[0.000110229776,0.00018036317,0.000042895812,0.00022928035,0.00018890189,0.000015838252,0.00016696812,0.0003721976,0.0000030846866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0076163164,0.00018703545,0.00085600937,0.00010418144,0.000015663696,0.000007681044,0.00020282452,0.000044975244,0.986863,0.0030058844,0.000044036016,0.0010523506],"study_design_scores_gemma":[0.0031025093,0.0038355691,0.0059297103,0.00018951108,0.0000095922915,0.000009735338,0.00014792946,0.014306282,0.971179,0.0008410694,0.00011805529,0.00033100485],"about_ca_topic_score_codex":0.000044871602,"about_ca_topic_score_gemma":0.00004366303,"teacher_disagreement_score":0.01568401,"about_ca_system_score_codex":0.000022235723,"about_ca_system_score_gemma":0.00007231207,"threshold_uncertainty_score":0.7354997},"labels":[],"label_agreement":null},{"id":"W2055027723","doi":"10.1016/s0169-328x(01)00324-2","title":"Identification of functional dopamine receptors in human teratocarcinoma NT2 cells","year":2002,"lang":"en","type":"article","venue":"Molecular Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"National Human Genome Research Institute","keywords":"Biology; Dopamine; Teratocarcinoma; Neuroscience; Receptor; Dopamine receptor; Identification (biology); Cell biology; Cellular differentiation; Biochemistry; Gene","score_opus":0.039713585540009956,"score_gpt":0.30777250190389116,"score_spread":0.2680589163638812,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055027723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99408734,0.0005104481,0.003991638,0.0002524396,0.00010611971,0.00027600076,0.000006047652,0.00000594885,0.0007640234],"genre_scores_gemma":[0.9970602,0.000029967756,0.00014384158,0.000060328715,0.000085763066,0.000048369446,0.000069205016,0.00002693222,0.002475411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99807894,0.00033587168,0.00036246667,0.00041382306,0.00047633878,0.0003325564],"domain_scores_gemma":[0.9992287,0.000030377108,0.000066285436,0.00039188846,0.0002070462,0.00007570206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00123378,0.00011702798,0.00013419644,0.0002533256,0.000095284304,0.000035973128,0.00024195145,0.00014987521,0.0005983192],"category_scores_gemma":[0.00015749295,0.00012384301,0.000085980486,0.0003622875,0.00011107001,0.000005259769,0.00011704388,0.00020688483,0.000029419085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019333555,0.00014677778,0.00025493227,0.000021452293,0.000014878246,0.000009672547,0.000048671445,0.0002428129,0.9945604,0.00051827397,0.003119865,0.0010429072],"study_design_scores_gemma":[0.00041298263,0.0002891846,0.00032114197,0.000014780348,0.0000019097033,0.0000032741623,0.00007858121,0.0005627659,0.99513316,0.000225143,0.0028375082,0.000119559256],"about_ca_topic_score_codex":0.000026190102,"about_ca_topic_score_gemma":0.000010258591,"teacher_disagreement_score":0.0038477962,"about_ca_system_score_codex":0.000030070227,"about_ca_system_score_gemma":0.000026255571,"threshold_uncertainty_score":0.6551176},"labels":[],"label_agreement":null},{"id":"W2055678521","doi":"10.1016/j.ddstr.2008.10.001","title":"Cognitive enhancing drugs for schizophrenia","year":2008,"lang":"en","type":"article","venue":"Drug Discovery Today Therapeutic Strategies","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Foothills Medical Centre","funders":"","keywords":"Schizophrenia (object-oriented programming); Cognition; Psychology; Dopamine; Dopamine hypothesis of schizophrenia; Neuroscience; Medicine; Psychiatry; Dopamine receptor D2","score_opus":0.01668047938715617,"score_gpt":0.26514548155943773,"score_spread":0.24846500217228157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055678521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9369671,0.0018807851,0.057570133,0.00006591849,0.00040170806,0.0005143286,0.000058102443,0.000034935056,0.0025070396],"genre_scores_gemma":[0.9958479,0.00040217832,0.0004798145,0.00033840493,0.00044485964,0.00016011111,0.00016624901,0.000046409463,0.002114063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871874,0.000058056412,0.00025168853,0.00044138377,0.00016312076,0.0003669991],"domain_scores_gemma":[0.9994492,0.0000737176,0.00009970028,0.00021622125,0.000100600046,0.000060551945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018120695,0.00025712725,0.00022223721,0.000045978195,0.0002926512,0.00012779482,0.00018761611,0.00011418252,0.00007456572],"category_scores_gemma":[0.000019662255,0.00022853883,0.0002012371,0.00007757523,0.00012429254,0.00003855138,0.00004439915,0.00009384149,0.0000140489865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006331458,0.00007341842,0.00005834575,0.000031535885,0.00020517404,0.0000031154552,0.0010577125,0.00013164368,0.9882924,0.0062405067,0.00029395582,0.0029790786],"study_design_scores_gemma":[0.0013658067,0.0002601165,0.00014737225,0.000050464187,0.000049057897,0.000018528159,0.007853736,0.00006348891,0.9806434,0.004313136,0.0048019914,0.00043292827],"about_ca_topic_score_codex":0.000020328886,"about_ca_topic_score_gemma":0.000020794976,"teacher_disagreement_score":0.05888086,"about_ca_system_score_codex":0.000012621079,"about_ca_system_score_gemma":0.00026928514,"threshold_uncertainty_score":0.93195426},"labels":[],"label_agreement":null},{"id":"W2055698508","doi":"10.1074/jbc.m109.069443","title":"Oligomeric Size of the M2 Muscarinic Receptor in Live Cells as Determined by Quantitative Fluorescence Resonance Energy Transfer","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Förster resonance energy transfer; Oligomer; Fluorescence; Chemistry; Acceptor; Tetramer; Biophysics; Chinese hamster ovary cell; Green fluorescent protein; Receptor; Crystallography; Biology; Biochemistry","score_opus":0.008923156651459142,"score_gpt":0.2311022402806891,"score_spread":0.22217908362922995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055698508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99848664,0.0008768737,0.00012621655,0.000060724513,0.00022061808,0.00004601263,0.000019687259,0.000001967932,0.00016127269],"genre_scores_gemma":[0.9974976,0.0008309414,0.0012067672,0.00009717653,0.00013960926,0.0000039562838,0.0000046136383,0.000009795578,0.00020954781],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988504,0.00007668804,0.00048797647,0.00022055832,0.00015973549,0.0002046132],"domain_scores_gemma":[0.9992521,0.00010518872,0.00023364813,0.00019247641,0.00013071488,0.00008588176],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028991903,0.00016141067,0.0002855305,0.0000109284365,0.000034173932,0.00000970985,0.00046296537,0.00032850297,0.0003341068],"category_scores_gemma":[0.000391583,0.000100049045,0.00022998954,0.00011203179,0.00019286614,0.0000051352868,0.00006454109,0.0003504418,0.0000012478531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024487058,0.000094209085,0.00039690948,0.000010994284,0.000018269811,0.0000034950049,0.000041252053,0.0000038746575,0.99813,0.00001743033,0.00018234843,0.0008563375],"study_design_scores_gemma":[0.00043399053,0.00037425093,0.0003297871,0.000042058084,0.000007844946,0.000025752684,0.00012060733,0.0000114743,0.9942368,0.00009766421,0.0041897427,0.00012998932],"about_ca_topic_score_codex":0.000017681039,"about_ca_topic_score_gemma":0.0000045169577,"teacher_disagreement_score":0.0040073944,"about_ca_system_score_codex":0.000011841555,"about_ca_system_score_gemma":0.000088190565,"threshold_uncertainty_score":0.40798816},"labels":[],"label_agreement":null},{"id":"W2055762135","doi":"10.1097/00005344-200412000-00005","title":"The Cardiovascular and Renal Effects of the Potent and Highly Selective μ Opioid Agonist [Dmt1]DALDA","year":2004,"lang":"en","type":"article","venue":"Journal of Cardiovascular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"National Institute on Drug Abuse","keywords":"(+)-Naloxone; Agonist; Pharmacology; Chemistry; Kidney; Antagonist; Internal medicine; Endocrinology; Diuresis; Opioid; Receptor; Medicine","score_opus":0.0034154792066221646,"score_gpt":0.20804228394610463,"score_spread":0.20462680473948247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055762135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8578281,0.13472612,0.0056295283,0.00023894181,0.0011686373,0.0003411005,0.0000029799944,0.0000030132285,0.00006161296],"genre_scores_gemma":[0.98378927,0.015069243,0.00032079717,0.00012500185,0.00064210815,0.000011017976,9.64624e-7,0.000021982982,0.000019596937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982967,0.00043225873,0.0003653858,0.00024112509,0.00040348622,0.00026108135],"domain_scores_gemma":[0.9990326,0.00005308247,0.0002273742,0.00029425,0.00028232008,0.00011033168],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001220434,0.00019218215,0.00050590927,0.000044741122,0.0002699201,0.000029305516,0.0002768753,0.00014973417,0.0000015950031],"category_scores_gemma":[0.00008668201,0.00011505719,0.0011990481,0.000110866946,0.00026341912,0.000009529153,0.00016606566,0.00029284146,2.7644393e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016600602,0.000041092448,0.000053277952,0.000077201265,0.010359017,0.000048498907,0.00012519055,0.007897485,0.96915734,0.00009926724,0.00029908234,0.011676557],"study_design_scores_gemma":[0.0028101692,0.0004914864,0.0008138367,0.000036524252,0.0016577851,0.00080531224,0.000049921622,0.00001116825,0.9239758,0.00033485828,0.068875246,0.00013785936],"about_ca_topic_score_codex":0.000024329363,"about_ca_topic_score_gemma":0.00000184328,"teacher_disagreement_score":0.12596123,"about_ca_system_score_codex":0.00003900605,"about_ca_system_score_gemma":0.00019103837,"threshold_uncertainty_score":0.4691896},"labels":[],"label_agreement":null},{"id":"W2055775644","doi":"10.1016/j.gene.2004.07.020","title":"Identification of a novel aminergic-like G protein-coupled receptor in the cnidarian Renilla koellikeri","year":2004,"lang":"en","type":"article","venue":"Gene","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Hôpital Saint-Luc","funders":"","keywords":"Biology; Receptor; Extracellular; Complementary DNA; G protein-coupled receptor; Transmembrane domain; Molecular biology; Amino acid; Cell biology; Biochemistry; Gene","score_opus":0.010258098508852271,"score_gpt":0.22867556194222058,"score_spread":0.21841746343336832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055775644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9687315,0.00022783209,0.030271333,0.00022322414,0.00013675094,0.00032200417,0.000012625744,0.0000049086616,0.00006979912],"genre_scores_gemma":[0.996344,0.00004166624,0.0029804974,0.000087518034,0.00013943664,0.000056975652,0.00008989347,0.000013811239,0.00024623936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991605,0.000028952016,0.00028310713,0.0002345631,0.00013987918,0.00015295176],"domain_scores_gemma":[0.9994601,0.0000034353252,0.0001231505,0.000326821,0.000060197217,0.000026306656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000374463,0.00010116279,0.00010543232,0.000036523063,0.000043887034,0.000018479099,0.00022016265,0.00010552045,0.000026367436],"category_scores_gemma":[0.000035456334,0.000078785815,0.00006514969,0.00013823977,0.00003200266,0.0000029831133,0.00003279087,0.0000569954,0.000006379691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033750377,0.000087290486,0.000010739294,0.000009018215,0.000011027215,6.142295e-7,0.0001409438,0.00075816433,0.9978794,0.0007953452,0.000034226163,0.00023952071],"study_design_scores_gemma":[0.00067830615,0.00012252723,0.00012189134,0.000012855024,0.0000057456487,0.0000052239716,0.00013137747,0.00010378498,0.99688375,0.00019509919,0.0016388698,0.00010058672],"about_ca_topic_score_codex":0.00007990431,"about_ca_topic_score_gemma":0.000044182154,"teacher_disagreement_score":0.02761244,"about_ca_system_score_codex":0.00001345393,"about_ca_system_score_gemma":0.00005360568,"threshold_uncertainty_score":0.32127923},"labels":[],"label_agreement":null},{"id":"W2055953592","doi":"10.1038/ncomms1605","title":"PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades","year":2011,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"Canadian Institutes of Health Research; Austrian Science Fund; National Institute of General Medical Sciences; Universität Innsbruck; Canada Research Chairs","keywords":"Cell biology; Protein kinase A; G protein-coupled receptor; Biology; Receptor; Signal transduction; G protein; Protein subunit; Biochemistry; Chemistry; Kinase","score_opus":0.022918401168091785,"score_gpt":0.24807489214666087,"score_spread":0.22515649097856907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055953592","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98741215,0.008230106,0.00021602567,0.00024939628,0.00026477218,0.00030480314,0.000031773372,0.000060778828,0.0032302113],"genre_scores_gemma":[0.9896538,0.00084733893,0.0076627405,0.0003002219,0.00011278707,0.00010000762,0.00049524906,0.000042138137,0.00078567374],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880385,0.00021012324,0.00028338918,0.0002961935,0.00015163013,0.00025480747],"domain_scores_gemma":[0.9975522,0.00003528326,0.00016780292,0.0018347076,0.00027462692,0.00013537619],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035091233,0.00019727118,0.00017945532,0.000068313486,0.00030583164,0.000025417661,0.0011074345,0.00063038873,0.0002798174],"category_scores_gemma":[0.00020692227,0.00018982183,0.00011092142,0.000165634,0.00022847965,0.00001080736,0.0003836685,0.0005535367,0.000026476182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036738973,0.00008460451,0.0009962433,0.000008018237,0.00009296941,9.359179e-7,0.00018319169,0.0000020671991,0.98980564,0.0063649453,0.0021085332,0.00031613547],"study_design_scores_gemma":[0.00049028493,0.00012914806,0.0043575037,0.0000499861,0.000041557385,0.000006676676,0.0002908224,0.00020961494,0.9375893,0.00037584637,0.056028035,0.00043124316],"about_ca_topic_score_codex":0.00013647293,"about_ca_topic_score_gemma":0.00074657495,"teacher_disagreement_score":0.0539195,"about_ca_system_score_codex":0.000020571148,"about_ca_system_score_gemma":0.00009586011,"threshold_uncertainty_score":0.774071},"labels":[],"label_agreement":null},{"id":"W2056023204","doi":"10.1124/jpet.103.053843","title":"Blockade of G Protein-Coupled Receptors and the Dopamine Transporter by a Transmembrane Domain Peptide: Novel Strategy for Functional Inhibition of Membrane Proteins in Vivo","year":2003,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"In vivo; Transmembrane protein; Transmembrane domain; Transporter; Chemistry; Receptor; Blockade; Pharmacology; Dopamine receptor; Membrane protein; Cell biology; Peptide; Transport protein; Membrane; Biology; Biochemistry","score_opus":0.016707500238070157,"score_gpt":0.2721190272372704,"score_spread":0.2554115269992002,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056023204","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906184,0.0037710345,0.0047805062,0.00015599716,0.00010635304,0.00052847614,0.000019287536,9.187554e-7,0.000019023577],"genre_scores_gemma":[0.9983235,0.0003757221,0.0010075326,0.00012727262,0.00006227935,0.000039057402,0.0000065255895,0.000012327857,0.000045754303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911696,0.00008788149,0.00044684584,0.00012027448,0.00010270078,0.00012536092],"domain_scores_gemma":[0.9995756,0.00002659705,0.00025982523,0.000038483533,0.000065540495,0.000033923614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004938299,0.00012662046,0.00026341886,0.00004630315,0.00004489493,0.000004775962,0.000048743994,0.00011638465,0.00010253804],"category_scores_gemma":[0.0000027531926,0.00009045436,0.000093940675,0.000049070226,0.00021040258,0.000010856615,0.000005277828,0.000111234156,1.5729968e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037829957,0.00035648272,0.000019066712,0.000047310477,0.0001812209,7.7935323e-7,0.00035466795,0.000103042235,0.9948017,0.000262042,0.000016331305,0.00007434899],"study_design_scores_gemma":[0.010929724,0.0012657011,0.00000595288,0.000021846363,0.00006291459,0.000044355802,0.000694415,0.00009941175,0.9853602,0.00013531241,0.0012912672,0.00008890589],"about_ca_topic_score_codex":0.0000035687865,"about_ca_topic_score_gemma":0.000001937956,"teacher_disagreement_score":0.009441519,"about_ca_system_score_codex":0.00000964242,"about_ca_system_score_gemma":0.000055767225,"threshold_uncertainty_score":0.36886218},"labels":[],"label_agreement":null},{"id":"W2056066002","doi":"10.1021/bi0345539","title":"D2 Dopamine Receptor Homodimerization Is Mediated by Multiple Sites of Interaction, Including an Intermolecular Interaction Involving Transmembrane Domain 4","year":2003,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Transmembrane domain; Transmembrane protein; Receptor; Biophysics; Chemistry; Dopamine receptor; Dopamine receptor D2; Biochemistry; Biology","score_opus":0.01398788448926183,"score_gpt":0.25430302157436246,"score_spread":0.24031513708510063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056066002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9878551,0.0007181438,0.010628893,0.00003415282,0.00021351787,0.000145206,0.00006364591,0.000027063677,0.00031428714],"genre_scores_gemma":[0.995361,0.00018233972,0.0024082153,0.00011056282,0.00010978436,0.000021973974,0.0016591216,0.000040601226,0.00010644666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984923,0.000105691804,0.0004493681,0.00050886703,0.00020428035,0.00023950895],"domain_scores_gemma":[0.99906695,0.000027627928,0.0002566597,0.00034142818,0.00018153375,0.00012581272],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025858323,0.0002593828,0.00022967145,0.00005888008,0.000102075646,0.00003873226,0.00018902175,0.0003001378,0.00037823836],"category_scores_gemma":[0.0002484915,0.00027801868,0.0001237191,0.00013008162,0.000050049737,0.000026768053,0.00004167037,0.00016588521,0.0000048567395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010645483,0.00014437866,0.00036735446,0.00007871201,0.00007078578,8.848434e-7,0.00019536834,0.000021617503,0.998227,0.000016846781,0.00048875797,0.00028183547],"study_design_scores_gemma":[0.0006461804,0.00017115491,0.0000055960654,0.0000731271,0.000017941611,0.00001420199,0.0010379513,0.00045542742,0.99215263,0.000019300001,0.0051128445,0.0002936257],"about_ca_topic_score_codex":0.00002368021,"about_ca_topic_score_gemma":0.0000051684183,"teacher_disagreement_score":0.008220677,"about_ca_system_score_codex":0.000044820306,"about_ca_system_score_gemma":0.000054276155,"threshold_uncertainty_score":0.9999672},"labels":[],"label_agreement":null},{"id":"W2056556818","doi":"10.1074/jbc.m406276200","title":"The Role of Subtype-specific Ligand Binding and the C-tail Domain in Dimer Formation of Human Somatostatin Receptors","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Receptor; Förster resonance energy transfer; Agonist; Cell biology; Photobleaching; Biology; G protein; Ligand (biochemistry); Chemistry; Signal transduction; Biophysics; Somatostatin receptor; Biochemistry; Fluorescence","score_opus":0.010318929883461517,"score_gpt":0.22567369712215157,"score_spread":0.21535476723869007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056556818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962091,0.0033187205,0.00013843337,0.00007606626,0.000038824383,0.00006389238,0.0000024041594,9.330039e-7,0.00015163343],"genre_scores_gemma":[0.99830496,0.0013062367,0.00028619647,0.000007239303,0.000073318675,0.0000024066921,0.0000064450296,0.000004257693,0.000008927963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991736,0.000052045143,0.00047090193,0.00008307702,0.00010617424,0.00011422704],"domain_scores_gemma":[0.99928373,0.00006195425,0.00045834255,0.00009323438,0.000070118454,0.000032597778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007198918,0.000084824474,0.00018978294,0.000014450114,0.0000716411,0.000013156785,0.00016498861,0.00013221444,0.00001148932],"category_scores_gemma":[0.00010059635,0.000042194002,0.00009596537,0.00006103176,0.00020536914,0.0000053205426,0.000048476453,0.00014075129,1.7785351e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020413108,0.000025997297,0.00082028634,0.00001010963,0.00001551968,6.5449404e-7,0.0001383038,0.000017558921,0.9978541,0.0002920705,0.000010717761,0.00061052793],"study_design_scores_gemma":[0.0010303848,0.00015126387,0.0001575155,0.00004444791,0.000004636211,0.000026526946,0.0013241583,0.0000023084972,0.9925285,0.0036647848,0.001011999,0.00005346478],"about_ca_topic_score_codex":0.0000032383373,"about_ca_topic_score_gemma":0.0000012487255,"teacher_disagreement_score":0.005325613,"about_ca_system_score_codex":0.000012619921,"about_ca_system_score_gemma":0.000021777885,"threshold_uncertainty_score":0.17206214},"labels":[],"label_agreement":null},{"id":"W2056565695","doi":"10.1016/s0166-4328(03)00116-5","title":"Long-term effects of BIBN-99, a selective muscarinic M2 receptor antagonist, on improving spatial memory performance in aged cognitively impaired rats","year":2003,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Morris water navigation task; Water maze; Antagonist; Muscarinic antagonist; Psychology; Muscarinic acetylcholine receptor; Working memory; Neuroscience; Receptor antagonist; Pharmacology; Medicine; Internal medicine; Receptor; Hippocampus; Cognition","score_opus":0.03518879884253147,"score_gpt":0.31637148069812593,"score_spread":0.2811826818555945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056565695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99822783,0.00020212302,0.00012506437,0.00003256259,0.00018902143,0.0009838047,0.000017412089,0.000012960811,0.00020923874],"genre_scores_gemma":[0.9988697,0.000072716844,0.0001569835,0.000045634042,0.00010760292,0.00014039241,0.000091994014,0.00004716151,0.00046779358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99687535,0.0009079211,0.0003631775,0.00061997946,0.0005169105,0.0007166806],"domain_scores_gemma":[0.9989125,0.00022806122,0.00011885607,0.00031073723,0.0002776921,0.00015215683],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016241618,0.00025105992,0.00030329943,0.00030958955,0.00020858832,0.000046329267,0.00027599934,0.00027160542,0.00008450095],"category_scores_gemma":[0.00067223085,0.00023866516,0.00013472409,0.0004303529,0.00017328399,0.000014386545,0.00012621724,0.00056917407,0.000011996701],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049194123,0.00023871018,0.04103399,0.00011477353,0.00002554328,0.000029564324,0.00020137672,0.0000047460603,0.9404722,0.000007694124,0.00012015895,0.017259328],"study_design_scores_gemma":[0.0014293388,0.0021039932,0.2067528,0.00013450041,0.000008526829,0.000007677469,0.00009366799,0.00002405909,0.78921497,0.0000056614613,0.000012026876,0.0002127937],"about_ca_topic_score_codex":0.00030401177,"about_ca_topic_score_gemma":0.0001597662,"teacher_disagreement_score":0.16571882,"about_ca_system_score_codex":0.000105107305,"about_ca_system_score_gemma":0.0003142158,"threshold_uncertainty_score":0.9732483},"labels":[],"label_agreement":null},{"id":"W2056801079","doi":"10.1016/j.bbagen.2009.01.010","title":"Mammalian diacylglycerol kinases: Molecular interactions and biological functions of selected isoforms","year":2009,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":164,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Cancer Institute","keywords":"Diacylglycerol kinase; Phosphatidic acid; Cell biology; Kinase; Phosphatidylinositol; Biology; Organelle; Biochemistry; Function (biology); Gene isoform; Enzyme; Protein kinase C; Chemistry; Phospholipid; Gene","score_opus":0.023475553717242276,"score_gpt":0.29190654686635503,"score_spread":0.2684309931491128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056801079","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6072999,0.3905044,0.00023352305,0.00006816516,0.0003804663,0.00090327725,0.00033210794,0.00006130252,0.00021684312],"genre_scores_gemma":[0.17651391,0.8180887,0.0009095489,0.00017592222,0.0006272998,0.00014203417,0.0030151606,0.00011576728,0.00041166093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967954,0.00036372046,0.00084498356,0.001134364,0.00025081803,0.000610677],"domain_scores_gemma":[0.99814534,0.000050334253,0.0006442248,0.00070774305,0.0001899856,0.00026236207],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018161852,0.0008691639,0.0014377361,0.0002514434,0.00018582818,0.00009844053,0.00047446747,0.00071692234,0.000060475966],"category_scores_gemma":[0.00010386159,0.0006872646,0.00082299026,0.00061473326,0.00017550259,0.000017949984,0.00027617207,0.00048575512,0.000016510327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072714574,0.00024203157,5.9423803e-7,0.0005713037,0.00041731613,0.0000070784226,0.000025795503,0.000002810054,0.9535385,0.00011165009,0.00070569105,0.04430457],"study_design_scores_gemma":[0.0005920298,0.0017569097,0.000066591805,0.0011583086,0.0008327769,0.000110306755,0.000032349708,0.000019183071,0.7987316,0.000104236635,0.19522187,0.0013737986],"about_ca_topic_score_codex":0.000044769447,"about_ca_topic_score_gemma":0.000012706933,"teacher_disagreement_score":0.430786,"about_ca_system_score_codex":0.000050541697,"about_ca_system_score_gemma":0.00031025198,"threshold_uncertainty_score":0.99955785},"labels":[],"label_agreement":null},{"id":"W2056831317","doi":"10.1139/y01-001","title":"Eicosatetraynoic acid (ETYA), a non-metabolizable analogue of arachidonic acid, blocks the fast-inactivating potassium current of rat pituitary melanotrophs","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Arachidonic acid; Potassium; Endocrinology; Internal medicine; Chemistry; Pituitary gland; Biochemistry; Biology; Medicine; Hormone; Enzyme; Organic chemistry","score_opus":0.008443984722483068,"score_gpt":0.24358319043768187,"score_spread":0.2351392057151988,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056831317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98649967,0.011114396,0.0006370713,0.00019909177,0.0013406244,0.00012173844,0.00002689812,0.0000011599983,0.000059361482],"genre_scores_gemma":[0.9974719,0.0015572483,0.00014300495,0.00024644987,0.0005142544,0.0000051024817,0.000023557192,0.000014369195,0.000024099141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986144,0.00023352337,0.00048592567,0.00020571219,0.00007475142,0.0003857362],"domain_scores_gemma":[0.9988762,0.000042852225,0.00048636348,0.00014659231,0.00020823475,0.00023975289],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034330983,0.00018908175,0.0004454126,0.00014926607,0.00016094839,0.000005612097,0.0003185417,0.00017475674,0.00054748607],"category_scores_gemma":[0.00003444244,0.00014162534,0.0001682719,0.0001519008,0.00029913423,0.000012323523,0.000042829302,0.00038687588,8.1049984e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019471547,0.00004254451,0.0010080506,0.000043757784,0.00021125562,0.000015247907,0.00016130746,0.00043241534,0.9941839,0.000036797723,0.0010060272,0.002663995],"study_design_scores_gemma":[0.0009452249,0.00072326785,0.0013066516,0.000025548989,0.00013838836,0.00015938425,0.00016119094,0.00015065493,0.990106,0.0003414066,0.0058022803,0.00013999637],"about_ca_topic_score_codex":0.0002647251,"about_ca_topic_score_gemma":0.00028689258,"teacher_disagreement_score":0.010972256,"about_ca_system_score_codex":0.000019723839,"about_ca_system_score_gemma":0.0005725037,"threshold_uncertainty_score":0.5994588},"labels":[],"label_agreement":null},{"id":"W2057026557","doi":"10.1016/j.cellsig.2007.05.015","title":"Inverse agonist-induced signaling and down-regulation of the platelet-activating factor receptor","year":2007,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Cell biology; Phosphorylation; Internalization; Signal transduction; Protein kinase C; Platelet-activating factor; Receptor; G protein-coupled receptor; Platelet-activating factor receptor; Biology; Chemistry; Biochemistry; Endocrinology","score_opus":0.016513608546574247,"score_gpt":0.22413362944121712,"score_spread":0.20762002089464288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057026557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9560873,0.00026680404,0.04293908,0.000017720373,0.00023135652,0.0002903367,0.0000049501887,0.000013835178,0.00014861715],"genre_scores_gemma":[0.9962433,0.0000150536625,0.003216636,0.000051696738,0.00029319298,0.000005214756,0.000031547657,0.000034296158,0.00010903642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986719,0.00006878567,0.00039440402,0.0003437151,0.00022734178,0.0002938543],"domain_scores_gemma":[0.9992519,0.000050032057,0.00027622294,0.00022763918,0.00010486388,0.00008932043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055669283,0.00019726774,0.0001858686,0.000053159427,0.00022846094,0.000035204983,0.00018263322,0.00021541165,0.00012036144],"category_scores_gemma":[0.00008378025,0.00016271089,0.00012650609,0.00014234646,0.00005810732,0.000010621384,0.00010037775,0.00016512301,0.0000024958956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004903517,0.000017570428,0.0001982668,0.000030424024,0.00003571595,8.313558e-7,0.00023193874,0.00041959854,0.9936833,0.00010828964,0.000009438956,0.0052156383],"study_design_scores_gemma":[0.00032395992,0.00008947362,0.00015270627,0.00007511459,0.000005429443,0.0000025068098,0.0002848918,0.0006443146,0.9962064,0.00009524193,0.0019187576,0.0002011912],"about_ca_topic_score_codex":0.000020559677,"about_ca_topic_score_gemma":0.000006652948,"teacher_disagreement_score":0.04015603,"about_ca_system_score_codex":0.000021664759,"about_ca_system_score_gemma":0.000048246904,"threshold_uncertainty_score":0.66351575},"labels":[],"label_agreement":null},{"id":"W2057073696","doi":"10.1016/j.cjca.2012.02.007","title":"An “I” on Cardiac Hypertrophic Remodelling: Imidazoline Receptors and Heart Disease","year":2012,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Medicine; Moxonidine; Signal transduction; Cell biology; G protein-coupled receptor; Pharmacology; Agonist; Endocrinology; Internal medicine; Biology","score_opus":0.034053839532571,"score_gpt":0.2726704041056461,"score_spread":0.2386165645730751,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057073696","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014883571,0.99548423,0.00055309146,0.000041391308,0.0020175169,0.00018690205,0.00009009689,0.0000026370171,0.00013578651],"genre_scores_gemma":[0.01897481,0.9740329,0.00022442476,0.000118154036,0.0063420166,0.0000076809365,0.00017273921,0.00007906054,0.000048243583],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99799675,0.0005228512,0.0005349717,0.00034519797,0.00011268776,0.0004875242],"domain_scores_gemma":[0.99753356,0.000029426854,0.000289354,0.00041998381,0.00014520725,0.0015824508],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00062718237,0.00037505882,0.001469293,0.0002759899,0.000115596114,0.00003481269,0.00028538454,0.00053336634,0.000020207333],"category_scores_gemma":[0.00007984934,0.00030730147,0.00066668494,0.00007419579,0.000119284305,0.00000715034,0.000019331348,0.0004406915,0.000007764411],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001833578,0.000016547916,0.00049877324,0.0019682506,0.0015933691,0.00017053241,0.00005782845,0.0024289615,0.0017401173,0.000530178,0.010245186,0.9805669],"study_design_scores_gemma":[0.0001041577,0.00037366498,0.000013806285,0.0004556801,0.0006335854,0.00021483314,0.00000951496,0.000002254595,0.000028440722,0.000052148065,0.99780256,0.00030936778],"about_ca_topic_score_codex":0.000046335837,"about_ca_topic_score_gemma":0.000016979751,"teacher_disagreement_score":0.98755735,"about_ca_system_score_codex":0.00007017216,"about_ca_system_score_gemma":0.0014149969,"threshold_uncertainty_score":0.9999379},"labels":[],"label_agreement":null},{"id":"W2057080045","doi":"10.1021/jm401090a","title":"Novel Carvedilol Analogues That Suppress Store-Overload-Induced Ca<sup>2+</sup>Release","year":2013,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"National Heart, Lung, and Blood Institute","keywords":"Chemistry; Carvedilol; Endoplasmic reticulum; Linker; Ryanodine receptor 2; Calcium; HEK 293 cells; Calcium channel; Bioassay; Pharmacology; Biophysics; Biochemistry; Heart failure; Ryanodine receptor; Internal medicine; Receptor","score_opus":0.015643616830679483,"score_gpt":0.2368225374610673,"score_spread":0.2211789206303878,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057080045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957245,0.0012170597,0.0015946261,0.00033070237,0.00027943845,0.00010631491,0.000017662649,0.000007496433,0.0007222099],"genre_scores_gemma":[0.9958656,0.0001646899,0.0007708374,0.0003765507,0.0022041074,0.000007770147,0.000052229763,0.00003531772,0.00052292796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811697,0.00003413041,0.00053467095,0.00029553843,0.0006303576,0.00038836058],"domain_scores_gemma":[0.99837023,0.000032742646,0.00043428096,0.0003270971,0.00039885717,0.00043677565],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004134429,0.00029255156,0.00042129448,0.00004906322,0.00008779865,0.000051829586,0.0004690843,0.0003259315,0.0010896241],"category_scores_gemma":[0.0002131948,0.00023436794,0.00027482776,0.00007875533,0.000078039855,0.000023815572,0.00009028118,0.00048112962,0.000012853338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010025578,0.00009844116,0.00029340183,0.000072220064,0.00014811977,0.000038320635,0.00015745108,0.00028239048,0.98818904,0.0000015525405,0.009621323,0.000997474],"study_design_scores_gemma":[0.0015343656,0.00039119614,0.00019746278,0.0001483804,0.00009797503,0.00072914484,0.0020096025,0.00068790856,0.9882166,0.000034138473,0.005662477,0.00029076915],"about_ca_topic_score_codex":0.000113963826,"about_ca_topic_score_gemma":0.0000015597483,"teacher_disagreement_score":0.003958846,"about_ca_system_score_codex":0.000056301906,"about_ca_system_score_gemma":0.00021471803,"threshold_uncertainty_score":0.9998235},"labels":[],"label_agreement":null},{"id":"W2057219688","doi":"10.1074/jbc.m110.178277","title":"An Interaction between L-prostaglandin D Synthase and Arrestin Increases PGD2 Production","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; HEK 293 cells; Chemistry; In vitro; Prostaglandin D2; ATP synthase; Wild type; Prostaglandin; Cytoplasm; Molecular biology; Enzyme; Biology; Biochemistry; Receptor; Gene; Mutant","score_opus":0.01940782076959609,"score_gpt":0.27808819660507866,"score_spread":0.2586803758354826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057219688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.999192,0.00012625885,0.00032939075,0.00006231443,0.00018189855,0.000040389594,0.0000064250944,0.0000061175742,0.0000552104],"genre_scores_gemma":[0.9969745,0.00009360043,0.0010423445,0.000021488724,0.0017927155,0.0000018041733,0.00004168078,0.0000070266933,0.00002478964],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999303,0.000037655565,0.00025891923,0.00019575568,0.000084451356,0.00012025436],"domain_scores_gemma":[0.9993692,0.000023601331,0.0002304929,0.00012580426,0.00010250219,0.00014839387],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038731398,0.00011127379,0.0001575693,0.000017506896,0.00005968553,0.00003215036,0.000115664545,0.00021991707,0.000099218625],"category_scores_gemma":[0.000526157,0.00007835772,0.0000618756,0.000035417586,0.00006982355,0.000010779305,0.000034186134,0.00029057064,6.612769e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011832408,0.00006841964,0.02141185,0.000009936467,0.000018628627,0.0000048507372,0.000006220941,0.0000042256124,0.9753383,0.0000018835195,0.00007472134,0.0029426466],"study_design_scores_gemma":[0.00020477115,0.0003605922,0.004388848,0.000017326092,0.000015846186,0.00026621032,0.000091998874,0.0000083755085,0.99271524,0.000118530996,0.0017028785,0.00010938051],"about_ca_topic_score_codex":0.000004727039,"about_ca_topic_score_gemma":0.0000010638598,"teacher_disagreement_score":0.017376948,"about_ca_system_score_codex":0.000006488795,"about_ca_system_score_gemma":0.000027485221,"threshold_uncertainty_score":0.31953353},"labels":[],"label_agreement":null},{"id":"W2057651741","doi":"10.1016/s1734-1140(11)70448-0","title":"Evaluation of constrained amino acids in the design of neurokinin 1 receptor- and bifunctional opioid – neurokinin 1 receptor ligands","year":2011,"lang":"en","type":"article","venue":"Pharmacological Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Bifunctional; Tachykinin receptor 1; Chemistry; Amino acid; Receptor; Opioid receptor; Stereochemistry; Pharmacology; Opioid; Biochemistry; Medicine; Neuropeptide; Substance P","score_opus":0.08977140943843412,"score_gpt":0.3071498800308903,"score_spread":0.21737847059245616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057651741","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99730545,0.0002712027,0.0009759426,0.00004339161,0.000387191,0.0004838104,0.000007763766,0.0000067674387,0.0005184626],"genre_scores_gemma":[0.9981267,0.00021854701,0.001267634,0.00015661787,0.00008858703,0.000079430414,0.00003084229,0.000010053198,0.000021587115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980481,0.00044397556,0.00052668445,0.00035601208,0.00044823097,0.00017698272],"domain_scores_gemma":[0.9991094,0.00008729313,0.0003296054,0.00015757779,0.00025677102,0.000059380814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030367463,0.00015040634,0.0002097637,0.000054278837,0.000041937103,0.000007549123,0.00012378606,0.00013938606,0.00088064285],"category_scores_gemma":[0.00056741387,0.00010568372,0.000072711606,0.00013624031,0.00015879374,0.000007713795,0.000063662745,0.00013453275,8.5996413e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021098497,0.00018053311,0.0031486016,0.000007944803,0.00003996563,0.00001171285,0.00015917534,0.00012136588,0.9927993,0.00004962795,0.00046163955,0.0028091657],"study_design_scores_gemma":[0.00068987417,0.00096395164,0.008948789,0.000011889552,0.000110117515,0.00007472397,0.00011590057,0.0005461709,0.98725057,0.0004991421,0.00065542274,0.00013342466],"about_ca_topic_score_codex":0.000007509824,"about_ca_topic_score_gemma":5.5453785e-7,"teacher_disagreement_score":0.0058001876,"about_ca_system_score_codex":0.000009945963,"about_ca_system_score_gemma":0.00015136685,"threshold_uncertainty_score":0.96424216},"labels":[],"label_agreement":null},{"id":"W2057948342","doi":"10.1016/j.clpt.2004.11.005","title":"Identification of a dysfunctional missense single nucleotide variant of human adenylyl cyclase VI","year":2005,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Adenylyl cyclase; ADCY9; ADCY3; ADCY10; Gs alpha subunit; ADCY6; cAMP-dependent pathway; Missense mutation; Forskolin; Biology; G protein; Molecular biology; Chemistry; Receptor; Internal medicine; Endocrinology; Mutation; Genetics; Gene; Medicine","score_opus":0.0516003922526732,"score_gpt":0.37043372810379693,"score_spread":0.3188333358511237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057948342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99534386,0.00050327316,0.0023105913,0.00067013904,0.00083458703,0.00017171864,0.000022721433,0.000011633243,0.00013147506],"genre_scores_gemma":[0.9945683,0.0002610341,0.00061450794,0.0031441487,0.0009679614,0.000007421987,0.000042369596,0.000024201736,0.0003700905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827164,0.00021524858,0.0008888681,0.00031146634,0.00013026812,0.00018249702],"domain_scores_gemma":[0.9989821,0.000085215055,0.0004203743,0.00023099764,0.00020141453,0.000079909805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005879915,0.00013823331,0.00026521052,0.00004312624,0.00006655494,0.000006375999,0.00020307007,0.00025196638,0.00042705823],"category_scores_gemma":[0.000019670899,0.00013503799,0.00021249408,0.0000710976,0.0002541082,0.0000054039133,0.00006167416,0.00016819178,0.000015367346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024452512,0.00083231577,0.00021877978,0.000014038899,0.00032765185,0.0000027605238,0.000035104305,0.000112428665,0.99407184,0.00005916844,0.001947075,0.0021343175],"study_design_scores_gemma":[0.0011720886,0.00073751126,0.00035174112,0.0000071031295,0.00026941777,0.00001065158,0.000026548036,0.0006235279,0.9775379,0.00011604509,0.019016864,0.00013060698],"about_ca_topic_score_codex":0.0000017807837,"about_ca_topic_score_gemma":0.0000021881117,"teacher_disagreement_score":0.017069789,"about_ca_system_score_codex":0.000013311795,"about_ca_system_score_gemma":0.00006606248,"threshold_uncertainty_score":0.5506689},"labels":[],"label_agreement":null},{"id":"W2057989030","doi":"10.1016/j.tem.2010.08.009","title":"An ATIPical family of angiotensin II AT2 receptor-interacting proteins","year":2010,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Cancer Research; Institut National Du Cancer; Centre National de la Recherche Scientifique; Ligue Contre le Cancer","keywords":"Receptor; Biology; Angiotensin II; Intracellular; Cell biology; Signal transduction; G protein-coupled receptor; Genetics","score_opus":0.030778290663684864,"score_gpt":0.3315525078068407,"score_spread":0.30077421714315583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057989030","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.031266972,0.96697575,0.00008724799,0.000019116942,0.00094540004,0.00024597644,0.000056341836,0.00001750907,0.00038566606],"genre_scores_gemma":[0.0053630993,0.9878199,0.0051626135,0.000036563393,0.000626943,0.00007337336,0.0003964135,0.000061795916,0.00045928106],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99764174,0.00031275686,0.00070736243,0.0007233912,0.00011414205,0.00050060963],"domain_scores_gemma":[0.99887896,0.00002832438,0.00037774758,0.0005395672,0.00006159676,0.00011383501],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002376113,0.00046292803,0.0014558422,0.00038871722,0.00009988602,0.000014320365,0.00034097885,0.0008184124,0.00012189045],"category_scores_gemma":[0.00008463225,0.0003906992,0.00033874132,0.00020109088,0.00017366755,0.000009899228,0.00023867632,0.00078794605,0.0000031197778],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026508345,0.00009785505,0.0000064763635,0.00017865542,0.00009103361,0.000007996329,0.00005682975,6.5937445e-7,0.059689187,0.0008248527,0.00007667415,0.93894327],"study_design_scores_gemma":[0.00042257758,0.00021924567,0.0000687566,0.00040959177,0.0001949615,0.00010170414,0.00002819612,0.0000036786737,0.009102273,0.000036775178,0.9890412,0.0003710456],"about_ca_topic_score_codex":0.00006086799,"about_ca_topic_score_gemma":0.0000405315,"teacher_disagreement_score":0.9889645,"about_ca_system_score_codex":0.000008073334,"about_ca_system_score_gemma":0.00008359302,"threshold_uncertainty_score":0.9998545},"labels":[],"label_agreement":null},{"id":"W2058005021","doi":"10.1139/cjpp-78-4-267","title":"Cardiovascular α&lt;sub&gt;1&lt;/sub&gt;-adrenoceptor subtypes: functions and signaling","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Phospholipase C; Endocrinology; Vasoconstriction; Internal medicine; Biology; Protein kinase C; G protein; Receptor; Adrenergic receptor; Signal transduction; Inotrope; Cell biology; Protein kinase A; Intracellular; Alpha (finance); Kinase; Biochemistry; Medicine","score_opus":0.007404032037804879,"score_gpt":0.21243228796724348,"score_spread":0.2050282559294386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058005021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9829869,0.015497984,0.00017215534,0.00015209339,0.00082456315,0.000113627175,0.000033552744,0.0000045060187,0.00021461492],"genre_scores_gemma":[0.99549156,0.0023279542,0.00010988692,0.00061308994,0.0011958546,0.000007151595,0.000031459334,0.00002536289,0.00019770082],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985922,0.00023595698,0.00033008365,0.00033060563,0.00007686537,0.00043429772],"domain_scores_gemma":[0.999029,0.000035296438,0.00012040157,0.00013692385,0.00014846525,0.0005299191],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00038193198,0.00021973834,0.00040604765,0.00013700448,0.0003213622,0.000020587802,0.00016455818,0.0002980929,0.0035545225],"category_scores_gemma":[0.000019542469,0.00020950075,0.000218073,0.000093927694,0.00026940583,0.000015290854,0.000021938873,0.00027958068,0.000014578891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012252497,0.000015416144,0.0001135379,0.000025505835,0.00056902063,0.000036485028,0.00009056234,0.00076358503,0.98841643,0.000032550524,0.0037184118,0.0060959426],"study_design_scores_gemma":[0.0011176286,0.0006268814,0.0004831464,0.000015860125,0.0002876076,0.0003831042,0.000056921173,0.000054431097,0.85192454,0.00030790357,0.1444667,0.0002752755],"about_ca_topic_score_codex":0.00007643075,"about_ca_topic_score_gemma":0.00022838243,"teacher_disagreement_score":0.14074829,"about_ca_system_score_codex":0.000024693947,"about_ca_system_score_gemma":0.0003847187,"threshold_uncertainty_score":0.99735636},"labels":[],"label_agreement":null},{"id":"W2058107116","doi":"10.3390/ph5050417","title":"Pathophysiology of GPCR Homo- and Heterodimerization: Special Emphasis on Somatostatin Receptors","year":2012,"lang":"en","type":"article","venue":"Pharmaceuticals","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Michael Smith Health Research BC","keywords":"G protein-coupled receptor; Receptor; Intracellular; Extracellular; Rhodopsin-like receptors; Effector; Biology; Drug discovery; Signal transduction; Cell biology; Cell signaling; G protein; Neuroscience; Computational biology; Bioinformatics; Biochemistry; Metabotropic receptor; Agonist","score_opus":0.022941030643886806,"score_gpt":0.3082165183531648,"score_spread":0.285275487709278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058107116","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99655586,0.0010362124,0.0008895012,0.00009942699,0.0006156078,0.00012980109,0.000018656636,0.000008095245,0.00064681197],"genre_scores_gemma":[0.9962235,0.00085535884,0.0009971247,0.00060778117,0.0011631033,0.000011462623,0.000043499724,0.000018328908,0.00007981014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991688,0.00010803859,0.00019812824,0.0001908523,0.000095438576,0.00023874221],"domain_scores_gemma":[0.9996194,0.00002777386,0.00006975824,0.00012805326,0.000034455603,0.000120510005],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017235924,0.00012333078,0.00016106096,0.000031752552,0.00005057364,0.0000073426277,0.00006989817,0.000094623094,0.0004813007],"category_scores_gemma":[0.00004546847,0.0001106145,0.000054906104,0.000055250697,0.00007672042,0.0000051894003,0.000056242247,0.00006190576,0.000017537448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000092424336,0.0000913979,0.0012231148,0.000016822283,0.00003447793,3.487367e-7,0.00012975906,0.000006246587,0.9730196,0.00042581192,0.0007536002,0.024206419],"study_design_scores_gemma":[0.00037923278,0.00018754667,0.00033113733,0.000008210204,0.000022202079,0.0000036905406,0.000045647786,0.000027724638,0.94547725,0.00014605267,0.053243056,0.00012826078],"about_ca_topic_score_codex":0.0000012367221,"about_ca_topic_score_gemma":1.6778627e-7,"teacher_disagreement_score":0.052489456,"about_ca_system_score_codex":0.0000044886924,"about_ca_system_score_gemma":0.000011829345,"threshold_uncertainty_score":0.52699053},"labels":[],"label_agreement":null},{"id":"W2058157760","doi":"10.1139/v10-149","title":"Towards the development of new subtype-specific muscarinic receptor radiopharmaceuticals — Radiosynthesis and ex vivo biodistribution of [<sup>18</sup>F]3-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethylthio)-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,6-tetrahydropyridine","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Ontario Ministry of Research and Innovation; University of North Carolina at Chapel Hill","keywords":"Radiosynthesis; Biodistribution; Chemistry; Muscarinic acetylcholine receptor; In vivo; Ex vivo; Radioligand; Radiochemistry; In vitro; Receptor; Pharmacology; Biochemistry","score_opus":0.025763887140742577,"score_gpt":0.25516736763152487,"score_spread":0.2294034804907823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058157760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99205893,0.0045983787,0.0016884666,0.000433008,0.00039951614,0.00018074246,0.00011207419,0.0000052879764,0.0005236079],"genre_scores_gemma":[0.988822,0.00064052816,0.009470704,0.000059790058,0.00070607546,0.0000040838136,0.000044177887,0.000044690834,0.00020797379],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99747366,0.000109023684,0.001123771,0.00038509682,0.00038034428,0.0005280783],"domain_scores_gemma":[0.99729514,0.00010424097,0.00068513816,0.0004897064,0.0004354696,0.0009903196],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001605461,0.00036456223,0.00059209927,0.00011271395,0.00019263325,0.000056208868,0.00068902725,0.0005206432,0.0018390721],"category_scores_gemma":[0.000604101,0.0003057549,0.00029852364,0.00025528934,0.00042233497,0.000021033276,0.00006602069,0.00069402315,0.0000029135929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011077548,0.000030674742,0.00037088405,0.00010150292,0.00018107425,0.000007023032,0.0005889408,0.000039520168,0.97845614,0.000031164975,0.002871251,0.01721106],"study_design_scores_gemma":[0.00069581746,0.00008274985,0.00023777146,0.000086486594,0.00006236995,0.00013029945,0.000445044,0.000037148315,0.89787203,0.000091008726,0.09998097,0.0002782726],"about_ca_topic_score_codex":0.00019496634,"about_ca_topic_score_gemma":0.0001347745,"teacher_disagreement_score":0.09710973,"about_ca_system_score_codex":0.00009108042,"about_ca_system_score_gemma":0.0029179852,"threshold_uncertainty_score":0.99993944},"labels":[],"label_agreement":null},{"id":"W2058606901","doi":"10.1124/mol.65.4.917","title":"Atrial Natriuretic Peptide-C Receptor-Induced Attenuation of Adenylyl Cyclase Signaling Activates Phosphatidylinositol Turnover in A10 Vascular Smooth Muscle Cells","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Adenylyl cyclase; Phosphatidylinositol; NPR1; Receptor; NPR2; ADCY9; Chemistry; Vascular smooth muscle; Natriuretic peptide; Internal medicine; Cell biology; Endocrinology; Signal transduction; Biochemistry; Smooth muscle; Biology; Medicine; Heart failure","score_opus":0.008586326219733941,"score_gpt":0.2514980224769917,"score_spread":0.24291169625725778,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058606901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99230504,0.0010519976,0.004799292,0.0001339643,0.0009613435,0.00065632665,0.000016637376,0.000022430133,0.00005298217],"genre_scores_gemma":[0.9970463,0.00017074261,0.0018237894,0.0003086066,0.00041399608,0.000040941548,0.00011030152,0.00006807091,0.00001724907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997584,0.00027434522,0.0006200372,0.00067087496,0.0003332375,0.0005175264],"domain_scores_gemma":[0.99904823,0.000040702555,0.00029824954,0.0003022225,0.00016584645,0.00014476776],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045641494,0.00035391186,0.00043391623,0.00018681411,0.000081069105,0.000023677227,0.000339916,0.0004345881,0.00035202331],"category_scores_gemma":[0.00006226909,0.0003815989,0.00039703026,0.00031469678,0.0000774237,0.00001766169,0.0001041725,0.00032379862,0.00002021185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023270558,0.00017258708,0.000061844315,0.000040712697,0.00015509895,0.00003370942,0.00021405285,0.019527534,0.9787225,0.000063734566,0.00010112075,0.0006744156],"study_design_scores_gemma":[0.0046000853,0.00045063955,0.00010883421,0.000042178286,0.00011963277,0.0000024634876,0.00008170187,0.00015064236,0.991536,0.00014596268,0.0023730383,0.0003888074],"about_ca_topic_score_codex":0.00010142196,"about_ca_topic_score_gemma":0.000010138786,"teacher_disagreement_score":0.01937689,"about_ca_system_score_codex":0.00010216268,"about_ca_system_score_gemma":0.00019821689,"threshold_uncertainty_score":0.99986356},"labels":[],"label_agreement":null},{"id":"W2058695766","doi":"10.3109/10799893.2010.506484","title":"Regulation of M<sub>2</sub>, M<sub>3</sub>, and M<sub>4</sub>muscarinic receptor expression in K562 chronic myelogenous leukemic cells by carbachol","year":2010,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Marmara Üniversitesi; University of Manitoba; L'Oreal USA","keywords":"Carbachol; K562 cells; Muscarinic acetylcholine receptor; Chronic myelogenous leukemia; Chemistry; Receptor; Molecular biology; Cell biology; Cancer research; Biology; Cell; Leukemia; Biochemistry; Immunology","score_opus":0.004735482099361811,"score_gpt":0.19742300563077322,"score_spread":0.19268752353141141,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058695766","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913786,0.0027951887,0.003849873,0.000068138535,0.0014842987,0.00036496646,0.00003241509,0.00001253312,0.0000139809445],"genre_scores_gemma":[0.9885299,0.0098153325,0.0004901858,0.000025853957,0.0009635459,0.000013465222,0.00008217842,0.00006794421,0.000011555525],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971245,0.00025523012,0.0011013082,0.00058718905,0.00046978518,0.0004620237],"domain_scores_gemma":[0.99836373,0.000050110346,0.0007687574,0.00025363016,0.00028230168,0.0002814438],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009958826,0.00043993298,0.00062553876,0.0002937629,0.00018966229,0.00006672012,0.00020736012,0.0006924893,0.00005871983],"category_scores_gemma":[0.00003671241,0.00041032067,0.00028694182,0.00025171402,0.00019700428,0.000092628456,0.000045494915,0.00077782717,0.0000022677557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005001656,0.0001320185,0.00017789713,0.00010546206,0.00007417597,0.000002338866,0.00030722562,0.00037827608,0.9296542,0.00000619417,0.0005655369,0.06809655],"study_design_scores_gemma":[0.0018226485,0.0013695811,0.0005606179,0.00022818598,0.00008972717,0.000119036355,0.00021974136,0.00013925508,0.99331504,0.00012586529,0.0015856115,0.00042466],"about_ca_topic_score_codex":0.000012807977,"about_ca_topic_score_gemma":0.000042179046,"teacher_disagreement_score":0.06767189,"about_ca_system_score_codex":0.00011418639,"about_ca_system_score_gemma":0.0002252686,"threshold_uncertainty_score":0.99983484},"labels":[],"label_agreement":null},{"id":"W2058923441","doi":"10.1083/jcb.201304015","title":"A G protein–coupled receptor and the intracellular synthase of its agonist functionally cooperate","year":2014,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Sherbrooke","funders":"Canadian Institutes of Health Research; U.S. Public Health Service","keywords":"G protein-coupled receptor; Biology; Agonist; Cell biology; Receptor; Intracrine; Autocrine signalling; Intracellular; Prostaglandin D2; HEK 293 cells; Signal transduction; Hsp90; Gq alpha subunit; Biochemistry","score_opus":0.006183302986083657,"score_gpt":0.20394930034652803,"score_spread":0.19776599736044437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058923441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98646486,0.0029999693,0.009282941,0.0005821356,0.0002319482,0.00017201959,0.0000045378915,0.0000015154008,0.00026005154],"genre_scores_gemma":[0.99787134,0.0007407556,0.00039486898,0.00016946945,0.00030637567,0.0000036670804,0.000007108947,0.00000991581,0.0004965188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889433,0.00044712622,0.0003468815,0.00009718944,0.00008066629,0.00013378532],"domain_scores_gemma":[0.9990494,0.000092370756,0.00038632046,0.0001571218,0.00026820094,0.000046545785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017846092,0.00010872378,0.00022556451,0.000024367326,0.0001042331,0.000011451585,0.00023251958,0.00011149311,0.00012480156],"category_scores_gemma":[0.00021958706,0.000052922063,0.000085455016,0.000044077624,0.00023536892,0.0000029623748,0.00006335248,0.00015571651,0.0000037766767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009895077,0.00002583958,0.000005659237,0.0000137330735,0.000058085985,2.6890805e-7,0.00006415302,0.00009508132,0.9970682,0.0009858209,0.00008832162,0.00060532714],"study_design_scores_gemma":[0.0012488565,0.00084010354,0.0000054253032,0.000015708076,0.000045297555,0.000030804338,0.000080924205,0.0005591128,0.9800649,0.0003075365,0.016731754,0.000069558875],"about_ca_topic_score_codex":0.0000062965387,"about_ca_topic_score_gemma":0.0000020930272,"teacher_disagreement_score":0.017003285,"about_ca_system_score_codex":0.000004354846,"about_ca_system_score_gemma":0.00006557473,"threshold_uncertainty_score":0.21580991},"labels":[],"label_agreement":null},{"id":"W2059334078","doi":"10.1038/ncb821","title":"β-Arrestins regulate a Ral-GDS–Ral effector pathway that mediates cytoskeletal reorganization","year":2002,"lang":"en","type":"article","venue":"Nature Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":135,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Cell biology; Cytoskeleton; Effector; Cytosol; Immunoprecipitation; Arrestin; Biology; Signal transduction; Chemistry; G protein-coupled receptor; Biochemistry; Cell","score_opus":0.005928945769451441,"score_gpt":0.20619444610835208,"score_spread":0.20026550033890064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059334078","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907613,0.0049661384,0.0011204508,0.00018202097,0.0013403778,0.00025556312,0.000047121615,0.000057830453,0.0012692361],"genre_scores_gemma":[0.995813,0.00041889437,0.0007535523,0.000468679,0.00085296837,0.000013744735,0.00074826676,0.00004430782,0.00088656874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854755,0.00016627491,0.00020134312,0.00054379273,0.00010566676,0.00043534816],"domain_scores_gemma":[0.999296,0.000039670183,0.00013290581,0.00032726023,0.0000827368,0.00012141903],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016658814,0.0002638895,0.00024067143,0.000062713516,0.000116713585,0.000023623186,0.00025645865,0.0010933691,0.0006428537],"category_scores_gemma":[0.00015630132,0.00021852537,0.00012531268,0.00013365896,0.00007967988,0.0000055482196,0.00010984415,0.0003709933,0.000074376745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028242714,0.0000419529,0.0012768657,0.000018825953,0.000025995216,0.000005632628,0.00004365972,0.000023214825,0.99447936,0.00013800822,0.0021019927,0.0018162779],"study_design_scores_gemma":[0.00056904636,0.0003772089,0.00031081284,0.000009376063,0.000016417836,0.000013213096,0.000015760615,0.0002702925,0.9456029,0.00014736906,0.05238713,0.00028050406],"about_ca_topic_score_codex":0.0000063167836,"about_ca_topic_score_gemma":0.00000917901,"teacher_disagreement_score":0.050285134,"about_ca_system_score_codex":0.000018763705,"about_ca_system_score_gemma":0.000026239251,"threshold_uncertainty_score":0.89112055},"labels":[],"label_agreement":null},{"id":"W2059551149","doi":"10.1038/nature09789","title":"Crystal structure of metarhodopsin II","year":2011,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":668,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Transducin; Rhodopsin; Heterotrimeric G protein; Schiff base; Chemistry; Opsin; Retinaldehyde; G protein-coupled receptor; Retinal; Ligand (biochemistry); Stereochemistry; Biophysics; G protein; Crystallography; Receptor; Biochemistry; Biology","score_opus":0.009179170606410218,"score_gpt":0.2289999854418168,"score_spread":0.21982081483540658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059551149","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952595,0.0012867879,0.00042202324,0.000013966905,0.00026178628,0.000056655954,0.00003112592,0.0000057070297,0.0026624233],"genre_scores_gemma":[0.992651,0.000016741964,0.0066033755,0.00017824225,0.0001332833,6.351268e-7,0.00004317779,0.000011162794,0.00036240031],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99953943,0.000019125147,0.0000946034,0.0001547961,0.000087611355,0.00010440745],"domain_scores_gemma":[0.99967664,0.0000015510822,0.000051841504,0.00017394815,0.00006282469,0.000033201657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000048459875,0.00008363544,0.00009565053,0.00002066755,0.000036833455,0.0000026283774,0.00013531663,0.00077037036,0.0006087233],"category_scores_gemma":[0.000027223961,0.00006741163,0.0000708674,0.000047370606,0.000026530237,0.0000016966985,0.000062980725,0.0003400624,6.908274e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034920733,0.000015061561,0.000107863,0.00000692989,0.000032576027,7.0924614e-7,0.00009033522,0.0000021438364,0.9971936,0.0013878592,0.0008469253,0.00028107958],"study_design_scores_gemma":[0.00014088741,0.00015311208,0.00033028537,0.000004555197,0.000012458736,0.0000062456033,0.000034142275,0.0000018580273,0.98381454,0.0009624812,0.014459105,0.00008033857],"about_ca_topic_score_codex":0.0000070122533,"about_ca_topic_score_gemma":0.0000075961466,"teacher_disagreement_score":0.01361218,"about_ca_system_score_codex":0.0000024960668,"about_ca_system_score_gemma":0.000026273696,"threshold_uncertainty_score":0.66650933},"labels":[],"label_agreement":null},{"id":"W2059651953","doi":"10.1007/s002130100777","title":"The adenosine A2A agonist CGS 21680 reverses the reduction in prepulse inhibition of the acoustic startle response induced by phencyclidine, but not by apomorphine and amphetamine","year":2001,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Apomorphine; Prepulse inhibition; Phencyclidine; Amphetamine; CGS-21680; Agonist; Chemistry; Pharmacology; Dopamine agonist; Adenosine; Startle response; Internal medicine; Endocrinology; Adenosine receptor; Dopamine; NMDA receptor; Medicine; Receptor","score_opus":0.00972221753371816,"score_gpt":0.26445452069331254,"score_spread":0.2547323031595944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059651953","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99306774,0.0014281587,0.00012459468,0.004133432,0.000675174,0.00044819675,0.00005040505,0.0000069993444,0.00006529538],"genre_scores_gemma":[0.99568653,0.0022402226,0.00002305784,0.00061875244,0.00016491143,0.00006984168,0.000037200676,0.0000191174,0.0011403882],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985754,0.00040329457,0.00033012038,0.0003137828,0.00013448206,0.00024291122],"domain_scores_gemma":[0.99932253,0.000093852876,0.00019845516,0.00026970226,0.0000687069,0.000046742814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064332463,0.00016212686,0.00015096579,0.000028254028,0.0002445671,0.000021467244,0.00019350061,0.00014474416,0.00008123858],"category_scores_gemma":[0.000107025044,0.00009787114,0.000057227207,0.00018082993,0.00021394106,0.000008366095,0.0000808584,0.00020004854,0.000002195598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025839268,0.000100606245,0.000057773064,0.000007084455,0.000030398303,0.0000012699467,0.00009547363,0.00004168373,0.9765276,0.000005438898,0.019880766,0.0006680229],"study_design_scores_gemma":[0.001585415,0.00032633863,0.00050375814,0.0000133626645,0.00004057097,0.000039757444,0.00029358757,0.000096109696,0.9795525,0.00007947466,0.017348059,0.00012106967],"about_ca_topic_score_codex":0.00008369555,"about_ca_topic_score_gemma":0.000025974692,"teacher_disagreement_score":0.0035146798,"about_ca_system_score_codex":0.000024364826,"about_ca_system_score_gemma":0.000042791788,"threshold_uncertainty_score":0.39910692},"labels":[],"label_agreement":null},{"id":"W2059922747","doi":"10.1016/j.biochi.2008.02.015","title":"Identification of ETA and ETB binding domains using ET-derived photoprobes","year":2008,"lang":"eu","type":"article","venue":"Biochimie","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"","keywords":"Receptor; Stereochemistry; Chemistry; Peptide; Transfection; Residue (chemistry); Binding site; G protein-coupled receptor; Ligand (biochemistry); Biochemistry; Molecular biology; Biology; Gene","score_opus":0.025702032375466845,"score_gpt":0.2664141078218429,"score_spread":0.24071207544637604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059922747","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860306,0.002716795,0.010484722,0.00005939697,0.00030877255,0.00022861749,0.0000590403,0.00000870814,0.000103344144],"genre_scores_gemma":[0.9933871,0.0024510608,0.0036378899,0.00007695981,0.00013343211,0.0000049594396,0.00006232778,0.0000344318,0.00021181669],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986248,0.00009898206,0.0004320753,0.00043278674,0.00016785241,0.00024350361],"domain_scores_gemma":[0.99919814,0.0000146384455,0.00030617186,0.00030163297,0.00009034565,0.000089095876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031476477,0.00021501676,0.00024819476,0.00008721104,0.00020688941,0.00003448984,0.00014294311,0.00026141023,0.000055456552],"category_scores_gemma":[0.000056246114,0.000218809,0.00011800351,0.00010838334,0.00016421096,0.00000993388,0.00012770273,0.000099247954,0.0000031261475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037962862,0.00006186296,0.0004573159,0.000071231094,0.00007946722,0.0000038626154,0.0002621702,0.00012755537,0.9984591,0.00020108931,0.000056585628,0.00018181474],"study_design_scores_gemma":[0.00045986546,0.00012762863,0.00031278387,0.00005659062,0.000055915978,0.000041181414,0.000185903,0.0013937039,0.99674934,0.000054552056,0.0003183082,0.00024420698],"about_ca_topic_score_codex":0.000045687193,"about_ca_topic_score_gemma":0.0000059204963,"teacher_disagreement_score":0.007356519,"about_ca_system_score_codex":0.000013920984,"about_ca_system_score_gemma":0.0001125172,"threshold_uncertainty_score":0.89227724},"labels":[],"label_agreement":null},{"id":"W2059939486","doi":"10.1074/jbc.m800778200","title":"Cholesterol-dependent Separation of the β2-Adrenergic Receptor from Its Partners Determines Signaling Efficacy","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Lipid raft; Signal transduction; Cell biology; Adenylyl cyclase; Receptor; G protein-coupled receptor; Phosphorylation; Cell signaling; Caveolae; Chemistry; Biology; Biophysics; Biochemistry","score_opus":0.03692422484243074,"score_gpt":0.28462058370271687,"score_spread":0.24769635886028613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059939486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984994,0.00075236545,0.00031073103,0.0000489361,0.00020142438,0.000058447436,0.000016817732,0.0000040948735,0.00010777918],"genre_scores_gemma":[0.9982102,0.0003949258,0.00041854603,0.00007809177,0.0006717887,0.000002309099,0.000027725335,0.000010138304,0.00018630423],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987761,0.00007937793,0.00054417097,0.00020716191,0.00022460855,0.00016860946],"domain_scores_gemma":[0.9989251,0.000042760923,0.00056652795,0.00018737178,0.00018432243,0.00009392582],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021510985,0.00016628123,0.00027259288,0.000012314945,0.00008810585,0.000012616418,0.0003657769,0.0002749425,0.00020148965],"category_scores_gemma":[0.0002219281,0.000099801546,0.00028557912,0.00006515711,0.00009339658,0.0000069786324,0.00008917632,0.0001890277,0.000002099234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012215249,0.00007976559,0.001915885,0.000007376872,0.000051595383,0.0000032950998,0.000034133976,0.00051194563,0.9968879,0.0000010480927,0.000163395,0.00022145685],"study_design_scores_gemma":[0.00060593523,0.00017780068,0.0012208462,0.000045479246,0.000019373898,0.00007560494,0.000050134415,0.000023118819,0.996409,0.00001652553,0.0012305604,0.00012562779],"about_ca_topic_score_codex":0.0000024196738,"about_ca_topic_score_gemma":3.4140942e-7,"teacher_disagreement_score":0.0010671654,"about_ca_system_score_codex":0.000016630256,"about_ca_system_score_gemma":0.00007009786,"threshold_uncertainty_score":0.4069789},"labels":[],"label_agreement":null},{"id":"W2060204391","doi":"10.1016/j.bbamem.2007.01.017","title":"Conformation of a double-membrane-spanning fragment of a G protein-coupled receptor: Effects of hydrophobic environment and pH","year":2007,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Biomembranes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Health Sciences Centre","funders":"","keywords":"Chemistry; Circular dichroism; Transmembrane domain; Transmembrane protein; Helix (gastropod); Folding (DSP implementation); Crystallography; Membrane protein; Stereochemistry; Alkyl; Membrane; G protein-coupled receptor; Biophysics; Receptor; Biochemistry; Organic chemistry; Biology","score_opus":0.0058900543157978935,"score_gpt":0.2195638009020112,"score_spread":0.2136737465862133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060204391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99792516,0.00056325644,0.0003944753,0.00005584087,0.000106098545,0.0008292494,0.00003074098,0.000013329005,0.00008186421],"genre_scores_gemma":[0.997837,0.00068607513,0.0010994292,0.000030033541,0.00007834237,0.000031570336,0.00015192115,0.000035691784,0.00004991316],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998161,0.00005675797,0.0007116237,0.00040660618,0.00034561605,0.0003183809],"domain_scores_gemma":[0.9985319,0.00004670263,0.00082824245,0.0004034251,0.000078038065,0.00011168639],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041114623,0.0003212726,0.0005040662,0.00018868524,0.000059479447,0.0000119441065,0.00023484335,0.00024368541,0.000026016973],"category_scores_gemma":[0.00001988307,0.00028929723,0.00019488123,0.00019183432,0.000259638,0.000020209576,0.0001491526,0.00009653608,0.000002338343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078452576,0.00024211362,0.000004119624,0.0009720098,0.000173282,7.61889e-7,0.0005555345,0.000016954275,0.9967806,0.00009842493,0.000007991092,0.0003636944],"study_design_scores_gemma":[0.0019077113,0.0009862693,0.00018168705,0.00023086104,0.00006687779,0.00000356513,0.00015841356,0.00015664322,0.9957726,0.00002089532,0.00022646388,0.00028802626],"about_ca_topic_score_codex":0.000056564066,"about_ca_topic_score_gemma":0.0000013723898,"teacher_disagreement_score":0.0011231855,"about_ca_system_score_codex":0.000016893027,"about_ca_system_score_gemma":0.00005167707,"threshold_uncertainty_score":0.9999559},"labels":[],"label_agreement":null},{"id":"W2060328852","doi":"10.1016/j.lfs.2006.11.025","title":"Regulation and function of the protein inhibitor of nitric oxide synthase (PIN)/dynein light chain 8 (LC8) in a human mast cell line","year":2006,"lang":"en","type":"article","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Dynein; Nitric oxide synthase; Cell biology; Immunoglobulin light chain; ATP synthase; Function (biology); Chemistry; Nitric oxide; Biology; Biochemistry; Immunology; Microtubule; Enzyme; Antibody","score_opus":0.007356891508562373,"score_gpt":0.20856242159286828,"score_spread":0.20120553008430592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060328852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983529,0.0004190233,0.00065222126,0.00007980626,0.000036611862,0.00016809595,0.0000025244576,0.0000021242029,0.00028669462],"genre_scores_gemma":[0.9992817,0.0000055407527,0.000330795,0.000015661279,0.00008253701,0.0000072445705,0.0000038891444,0.0000033440274,0.0002692639],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933565,0.00005080744,0.00020583223,0.00017312517,0.00013939786,0.000095209194],"domain_scores_gemma":[0.9997084,0.000005182246,0.00014058527,0.00009509421,0.000031852982,0.00001887058],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033970148,0.000062662795,0.00008732949,0.000062254636,0.000076664255,0.000008957316,0.00009168701,0.00006004321,0.000011320234],"category_scores_gemma":[0.000032336953,0.000043711632,0.00003255002,0.00025206458,0.000103221,0.000006291248,0.000041839132,0.000032697277,1.7578247e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013678529,0.000036457128,0.0015200602,0.000019938876,0.000001126965,6.606979e-8,0.000013042386,0.000300734,0.9975206,0.00037989483,0.000025769757,0.00016861419],"study_design_scores_gemma":[0.00018677101,0.00016352902,0.005768203,0.000039661416,0.000003763135,3.0415174e-7,0.00009215624,0.00034851625,0.99261147,0.0005993979,0.00013229782,0.00005390931],"about_ca_topic_score_codex":0.00012257052,"about_ca_topic_score_gemma":0.000051265455,"teacher_disagreement_score":0.0049091266,"about_ca_system_score_codex":0.0000033719678,"about_ca_system_score_gemma":0.00003736555,"threshold_uncertainty_score":0.17825086},"labels":[],"label_agreement":null},{"id":"W2061293585","doi":"10.1177/0091270003262951","title":"Rheumatoid Arthritis Does Not Reduce the Pharmacodynamic Response to Valsartan","year":2004,"lang":"en","type":"article","venue":"The Journal of Clinical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Rheumatoid arthritis; Valsartan; Medicine; Pharmacodynamics; Inflammation; Pharmacology; Internal medicine; Arthritis; Pharmacokinetics; Tumor necrosis factor alpha; Endocrinology; Blood pressure","score_opus":0.02884002884328935,"score_gpt":0.38890449552481066,"score_spread":0.3600644666815213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061293585","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97345316,0.0008645671,0.0018555816,0.01954825,0.0039961464,0.00022128645,0.000009166954,0.0000058767237,0.00004597605],"genre_scores_gemma":[0.98218405,0.0075725215,0.00044866116,0.0077529363,0.0018241658,0.0000062070053,0.000001197861,0.000024094987,0.00018616201],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99676025,0.0014035774,0.0010987822,0.00018935281,0.00024351125,0.0003045061],"domain_scores_gemma":[0.9981536,0.0006301705,0.00054194836,0.00023710787,0.00022001883,0.00021710483],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006589528,0.00016605819,0.0003949088,0.000045213877,0.00019607582,0.0000202306,0.0007612038,0.00014489685,0.00031898476],"category_scores_gemma":[0.00069233734,0.00008202962,0.0003070671,0.000102739454,0.00021339908,0.000007927248,0.0001593046,0.0005718,0.000031182648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.007579868,0.00013567788,0.000020904348,0.0000019908584,0.0001829549,0.000020240781,0.00012734829,0.0021529768,0.9809726,0.00002856992,0.004075572,0.0047013247],"study_design_scores_gemma":[0.0035409057,0.0017799345,0.00031741871,0.00003330383,0.000071421506,0.00032325304,0.00018240056,0.000040984967,0.91890377,0.00063764805,0.0740079,0.0001610613],"about_ca_topic_score_codex":0.00000744871,"about_ca_topic_score_gemma":0.0000065724194,"teacher_disagreement_score":0.06993233,"about_ca_system_score_codex":0.000020840756,"about_ca_system_score_gemma":0.00030549124,"threshold_uncertainty_score":0.34926596},"labels":[],"label_agreement":null},{"id":"W2061303359","doi":"10.1139/bcb-78-3-217","title":"Function- and agonist-specific Ca&lt;sup&gt;2+&lt;/sup&gt; signalling: The requirement for and mechanism of spatial and temporal complexity in Ca&lt;sup&gt;2+&lt;/sup&gt; signals","year":2000,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Extracellular; Intracellular; Biology; Cytosol; Cell biology; Agonist; Function (biology); Signal transduction; Biophysics; Biochemistry; Receptor; Enzyme","score_opus":0.024493537073336288,"score_gpt":0.23618485391524938,"score_spread":0.21169131684191309,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061303359","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9828146,0.011113078,0.003499876,0.00023660151,0.00013771786,0.00081986724,0.00048814638,0.0000252365,0.0008648905],"genre_scores_gemma":[0.99272346,0.0034346336,0.001065614,0.00021429773,0.00053387356,0.000115887466,0.0009780525,0.000056544675,0.00087764877],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963811,0.00023169095,0.0009438079,0.001409103,0.00023566799,0.00079861004],"domain_scores_gemma":[0.99848986,0.00013807732,0.00035054924,0.00053604855,0.00017447022,0.00031100932],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009296279,0.0007031072,0.00080651045,0.00008524829,0.00048164366,0.00010672887,0.00034296952,0.00089046283,0.00061124127],"category_scores_gemma":[0.00004805038,0.0005963984,0.00019441746,0.00013988503,0.00079003564,0.00002228843,0.0002614481,0.00028657212,0.0000040472764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008952833,0.00018564993,0.0004531677,0.00024534736,0.00013171388,0.0000066667612,0.00018065023,0.000048627506,0.9923778,0.0009518898,0.00061964185,0.0039035422],"study_design_scores_gemma":[0.0031544392,0.0016710103,0.00016904372,0.000091024325,0.00013983111,0.000060218976,0.0003479861,0.0027498272,0.937452,0.004572452,0.048683625,0.00090851233],"about_ca_topic_score_codex":0.000109237764,"about_ca_topic_score_gemma":0.00007652921,"teacher_disagreement_score":0.054925792,"about_ca_system_score_codex":0.000040720104,"about_ca_system_score_gemma":0.00013649388,"threshold_uncertainty_score":0.99964875},"labels":[],"label_agreement":null},{"id":"W2061767937","doi":"10.1038/mp.2011.109","title":"Pharmacogenetics of antipsychotic-induced weight gain: review and clinical implications","year":2011,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":262,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Risperidone; Antipsychotic; Clozapine; Olanzapine; Pharmacogenetics; Medicine; Weight gain; Schizophrenia (object-oriented programming); Psychiatry; Psychology; Bioinformatics; Internal medicine; Genetics; Biology; Gene; Body weight","score_opus":0.054246188533680705,"score_gpt":0.38644165167864963,"score_spread":0.33219546314496895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061767937","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015817555,0.99556834,0.0017364712,0.000090309666,0.00082784606,0.0009453972,0.00007012322,0.000012916493,0.0005904468],"genre_scores_gemma":[0.00010332571,0.99431384,0.004164983,0.000652375,0.00028602735,0.00006610599,0.00023615734,0.000109791305,0.00006740568],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972142,0.00033939458,0.0012128906,0.00081017445,0.000119352575,0.00030396605],"domain_scores_gemma":[0.9979632,0.000014837118,0.00069554313,0.0009952975,0.00012388104,0.00020725241],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045846475,0.000495007,0.0014177929,0.00008529629,0.00005975001,0.000013329007,0.00051091425,0.00049541274,0.00009770547],"category_scores_gemma":[0.000038695354,0.00043847176,0.0009219684,0.0002091295,0.000085169115,0.000002357081,0.00017014008,0.00033653667,0.000015558602],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021909334,0.0005951939,0.00020254559,0.04455049,0.0020521283,0.0000053702934,0.0000057145153,1.3430456e-7,0.0055113006,0.0032962654,0.009380264,0.9343787],"study_design_scores_gemma":[0.00032464918,0.00030976944,0.000011967988,0.0063256873,0.0037579776,0.00009790397,0.0000017370307,4.7280113e-7,0.0008107792,0.00030510334,0.98746336,0.0005906125],"about_ca_topic_score_codex":0.0000021615565,"about_ca_topic_score_gemma":0.0000013398288,"teacher_disagreement_score":0.9780831,"about_ca_system_score_codex":0.0000063684724,"about_ca_system_score_gemma":0.00032498976,"threshold_uncertainty_score":0.9998067},"labels":[],"label_agreement":null},{"id":"W2061998059","doi":"10.1016/j.bmcl.2009.05.020","title":"Synthesis and activity of quinolinylmethyl P1′ α-sulfone piperidine hydroxamate inhibitors of TACE","year":2009,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Piperidine; Sulfone; Chemistry; Enzyme; Stereochemistry; Enzyme inhibitor; Chemical synthesis; Organic chemistry; In vitro; Biochemistry","score_opus":0.006178394194108985,"score_gpt":0.21309322198977954,"score_spread":0.20691482779567055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061998059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99698156,0.0007336044,0.00093636836,0.0010656479,0.000073316514,0.00008754088,0.000018364108,0.000011832867,0.00009177436],"genre_scores_gemma":[0.9988566,0.0002491798,0.00035618347,0.00018267552,0.0002960914,0.0000033915412,0.000015140608,0.00001890312,0.000021826168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987953,0.000035383662,0.00032292257,0.00035734207,0.00024568036,0.0002434133],"domain_scores_gemma":[0.99924797,0.000028414814,0.00024728358,0.0003060019,0.000049811988,0.00012052623],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027150076,0.00022095957,0.00036273405,0.00003120656,0.000041223757,0.0000063140355,0.00018241694,0.00017830977,0.0000962907],"category_scores_gemma":[0.00016847241,0.00020418083,0.00009666353,0.0001208226,0.00016996036,0.000005998174,0.000058187565,0.0001251979,5.388269e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000111994195,0.000061341816,0.00014134249,0.00012121058,0.00004893333,0.0000045126026,0.00004666821,0.0000035629407,0.996306,0.0000033554768,0.00021760083,0.0029334684],"study_design_scores_gemma":[0.00040232769,0.0001297116,0.00048241124,0.0001079264,0.000059196187,0.000030958105,0.000075668046,0.000019926856,0.9982514,0.0000126275345,0.00024003952,0.000187854],"about_ca_topic_score_codex":0.0000213661,"about_ca_topic_score_gemma":4.1717834e-7,"teacher_disagreement_score":0.0027456144,"about_ca_system_score_codex":0.000017677552,"about_ca_system_score_gemma":0.00004822667,"threshold_uncertainty_score":0.83262527},"labels":[],"label_agreement":null},{"id":"W2062239193","doi":"10.1074/jbc.m308177200","title":"The 5-Hydroxytryptamine(1A) Receptor Is Stably Palmitoylated, and Acylation Is Critical for Communication of Receptor with Gi Protein","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; University of Ottawa","keywords":"Palmitoylation; G protein-coupled receptor; Heterotrimeric G protein; Biochemistry; Receptor; Cell biology; 5-HT7 receptor; 5-HT5A receptor; G protein-coupled receptor kinase; Chemistry; Biology; Cysteine; G protein; 5-HT receptor","score_opus":0.014793253384125947,"score_gpt":0.25580388751383093,"score_spread":0.24101063412970497,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062239193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99271774,0.0018132001,0.0036044803,0.0015444722,0.000031193416,0.0001767331,0.000035463127,0.0000036811612,0.00007304324],"genre_scores_gemma":[0.9870251,0.000855396,0.011673029,0.00009682924,0.0001790911,0.000014489776,0.00003102243,0.000012125577,0.000112932576],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902636,0.00004066386,0.00042657013,0.00017783268,0.00015001875,0.00017856908],"domain_scores_gemma":[0.99888355,0.00007806404,0.00035026783,0.00021168377,0.0003850904,0.00009136253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041727474,0.0001425125,0.0002130567,0.00001101741,0.0001484848,0.000032246524,0.00023441961,0.00026887577,0.00006312396],"category_scores_gemma":[0.00034396167,0.000083271196,0.000109928646,0.000058343263,0.00022900102,0.000009446587,0.000057309557,0.00018390402,5.0150055e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054771145,0.00006061801,0.00014847593,0.000040996736,0.00005271243,3.3070023e-7,0.00004790765,0.000008391402,0.9977887,0.00010774629,0.00027743916,0.0009189176],"study_design_scores_gemma":[0.0008223599,0.0008977422,0.000050129267,0.00010852593,0.000017902574,0.00002630169,0.0002837965,0.000015250516,0.99042016,0.0009218704,0.006314357,0.00012160407],"about_ca_topic_score_codex":0.0000024498797,"about_ca_topic_score_gemma":3.1355873e-7,"teacher_disagreement_score":0.0080685485,"about_ca_system_score_codex":0.000021889982,"about_ca_system_score_gemma":0.000077179226,"threshold_uncertainty_score":0.33957008},"labels":[],"label_agreement":null},{"id":"W2062513329","doi":"10.1016/s0167-0115(02)00201-x","title":"GIP, a G-protein-coupled receptor interacting protein","year":2002,"lang":"en","type":"article","venue":"Regulatory Peptides","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Transmembrane domain; Transmembrane protein; G protein-coupled receptor; Cell biology; Biology; Vesicle-associated membrane protein 8; Cytosol; Chemistry; Amino acid; Receptor; Biochemistry; Membrane protein; Biophysics; Membrane","score_opus":0.015369155970088332,"score_gpt":0.21984515870525811,"score_spread":0.20447600273516978,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062513329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996685,0.00087785034,0.0006939554,0.0001093257,0.000172183,0.00038452205,0.0000048208317,0.00005351361,0.00101879],"genre_scores_gemma":[0.98517853,0.00002107269,0.0038064716,0.00009650754,0.0006095286,0.00008528696,0.00002639206,0.00005582433,0.010120402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985872,0.00006138286,0.00030437147,0.0004757177,0.00020830649,0.0003630463],"domain_scores_gemma":[0.9991742,0.00000952957,0.00015202523,0.00045190027,0.00008124717,0.0001311291],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00025025845,0.00024288315,0.00020364097,0.000057376397,0.00016819879,0.000063091684,0.00022906547,0.00018567215,0.001965507],"category_scores_gemma":[0.00013429792,0.0002326358,0.00017257182,0.000088381414,0.00006239574,0.000012928127,0.00010507107,0.00014644017,0.00019831877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030312656,0.000047106267,0.000062401166,0.000026722864,0.000042410342,0.0000026199034,0.000092492235,0.000032870335,0.9947842,0.00020875476,0.0019271608,0.0027429664],"study_design_scores_gemma":[0.00036883348,0.00020364004,0.00006585534,0.00012870198,0.0000084716885,0.000010810636,0.00013722731,0.00081138196,0.9651365,0.00009198772,0.032700438,0.00033612666],"about_ca_topic_score_codex":0.000013452314,"about_ca_topic_score_gemma":0.000006487197,"teacher_disagreement_score":0.030773275,"about_ca_system_score_codex":0.000031448413,"about_ca_system_score_gemma":0.000021364602,"threshold_uncertainty_score":0.99894685},"labels":[],"label_agreement":null},{"id":"W2062530716","doi":"10.1016/j.bbr.2005.07.030","title":"Impaired response to amphetamine and neuronal degeneration in the nucleus accumbens of autoimmune MRL-lpr mice","year":2005,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Nucleus accumbens; Dopamine; Amphetamine; Dopaminergic; Medicine; Endocrinology; Neuroscience; Lesion; Internal medicine; Psychology; Pathology","score_opus":0.06434362628432001,"score_gpt":0.35467698135894465,"score_spread":0.29033335507462465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062530716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951011,0.0001977045,0.000086909306,0.0042048823,0.000028800487,0.00033292454,0.000016104314,0.000004198143,0.000027357071],"genre_scores_gemma":[0.9981015,0.000022327125,0.0008552678,0.00028407463,0.000080486345,0.000035762627,0.00003876875,0.000015060588,0.00056676636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822176,0.00065347034,0.0002256834,0.00026472108,0.000329332,0.00030504496],"domain_scores_gemma":[0.9993939,0.00013257205,0.00003244573,0.0002573574,0.00011695079,0.00006681922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002370729,0.00009778989,0.000112070426,0.000110115005,0.000112138485,0.00004747996,0.00025976117,0.000096548334,0.00004934918],"category_scores_gemma":[0.0003943348,0.000077121906,0.00004402946,0.00020776514,0.000072426825,0.000007283629,0.00015079082,0.00017247857,0.00000495123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044509166,0.00006482458,0.0014669494,0.0000034660388,0.000003136355,0.0000037341015,0.00037240345,0.00008004267,0.9919947,0.000054562955,0.0009744295,0.004536697],"study_design_scores_gemma":[0.0006755707,0.0009147266,0.15584053,0.000015971793,0.00000448773,0.00002166493,0.0004232666,0.00035503044,0.835631,0.000016326887,0.0059657292,0.00013569366],"about_ca_topic_score_codex":0.00016220927,"about_ca_topic_score_gemma":0.00024399186,"teacher_disagreement_score":0.15636367,"about_ca_system_score_codex":0.000021803267,"about_ca_system_score_gemma":0.000072838186,"threshold_uncertainty_score":0.314494},"labels":[],"label_agreement":null},{"id":"W2062994804","doi":"10.1038/sj.npp.1300467","title":"Reduction in Acetylcholine Release in the Hippocampus of Dopamine D5 Receptor-Deficient Mice","year":2004,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Douglas College","funders":"Canadian Institutes of Health Research; McGill University; Health Research","keywords":"Acetylcholine; Hippocampal formation; Hippocampus; Endocrinology; Agonist; Internal medicine; Receptor; Muscarinic acetylcholine receptor; Cholinergic; Chemistry; Neurotransmission; Biology; Medicine","score_opus":0.010500261186365862,"score_gpt":0.2753299192511128,"score_spread":0.2648296580647469,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062994804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99699384,0.0005637037,0.00021809766,0.0007602207,0.0009597065,0.00030349617,0.000004783185,0.000007065124,0.00018910372],"genre_scores_gemma":[0.99781597,0.0007586359,0.00031399756,0.0007477214,0.0002311976,0.000039045546,0.000026578831,0.000020369802,0.00004647096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864155,0.0002408972,0.00036091372,0.00037071673,0.00012506568,0.00026086372],"domain_scores_gemma":[0.99954987,0.000017570635,0.000119797725,0.00022244031,0.000048612637,0.000041729996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037454074,0.00014504495,0.00016510545,0.0001191588,0.00003261002,0.0000066130087,0.0002699873,0.00012815878,0.00007554527],"category_scores_gemma":[0.000049310005,0.00012246758,0.00006627491,0.00032249038,0.00007365151,0.0000048045217,0.000043116353,0.00025325504,0.000011055776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040138877,0.00032806114,0.00009310585,0.000012181261,0.00000664097,0.000009584893,0.0001900571,0.005182084,0.98841864,0.00004399908,0.0003484751,0.004965762],"study_design_scores_gemma":[0.0054680025,0.00095342036,0.0012146359,0.00002700447,0.000018999039,0.00012287749,0.00039219315,0.00006629957,0.979312,0.00038241327,0.0117989145,0.00024320836],"about_ca_topic_score_codex":0.000056670528,"about_ca_topic_score_gemma":0.000020825324,"teacher_disagreement_score":0.01145044,"about_ca_system_score_codex":0.00002542779,"about_ca_system_score_gemma":0.000053751402,"threshold_uncertainty_score":0.4994083},"labels":[],"label_agreement":null},{"id":"W2063154584","doi":"10.1210/me.2009-0013","title":"Regulation of GPR54 Signaling by GRK2 and β-Arrestin","year":2009,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; Western University; Children’s Health Research Institute; Lawson Health Research Institute","funders":"Medical Research Council; Canadian Institutes of Health Research; Children's Health Research Institute","keywords":"Biology; G protein-coupled receptor; HEK 293 cells; Beta adrenergic receptor kinase; Cell biology; Signal transduction; G protein-coupled receptor kinase; Receptor; Cell signaling; Gq alpha subunit; Biochemistry","score_opus":0.0048477061773161455,"score_gpt":0.22198603212016102,"score_spread":0.21713832594284488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063154584","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986604,0.0019339035,0.010739026,0.00016683205,0.000045088564,0.00009847897,0.0000029109372,0.000007467359,0.000402309],"genre_scores_gemma":[0.99781156,0.00008947686,0.0017749134,0.00019368857,0.000023214649,0.0000044603767,0.000039426937,0.000009793267,0.000053484197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999165,0.00006095814,0.00020500307,0.00027077098,0.00007111368,0.0002271381],"domain_scores_gemma":[0.9996932,0.000007029236,0.00006610216,0.00016580235,0.00003053785,0.00003732592],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000076211894,0.00010867799,0.00015153362,0.00006149101,0.000021140877,0.0000060089073,0.00008597643,0.000097029115,0.000026633636],"category_scores_gemma":[0.000042508254,0.00011542199,0.000039377894,0.00006484936,0.000040611463,0.0000024894982,0.000032873486,0.00006617014,0.0000010253178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003164963,0.000027128997,0.0005238667,0.000004909438,0.000008642175,0.000008719523,0.000015078383,0.00020609294,0.9929593,0.0014055811,0.00008181584,0.004727178],"study_design_scores_gemma":[0.0004578474,0.0002939462,0.0015699571,0.000009971223,0.0000065973113,0.000024646375,0.00001902256,0.00010362674,0.99442613,0.0017593387,0.0012153568,0.00011353827],"about_ca_topic_score_codex":0.000014458579,"about_ca_topic_score_gemma":0.0000024792241,"teacher_disagreement_score":0.011207558,"about_ca_system_score_codex":0.0000054906855,"about_ca_system_score_gemma":0.000014114849,"threshold_uncertainty_score":0.47067723},"labels":[],"label_agreement":null},{"id":"W2063158176","doi":"10.1002/hipo.21001","title":"Sphingomyelinase selectively reduces M1 muscarinic receptors in rat hippocampal membranes","year":2012,"lang":"en","type":"article","venue":"Hippocampus","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"","keywords":"Muscarinic acetylcholine receptor; Neuroscience; Hippocampal formation; Chemistry; Receptor; Hippocampus; Psychology; Biochemistry","score_opus":0.012775774295956098,"score_gpt":0.24986660654290602,"score_spread":0.2370908322469499,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063158176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99302644,0.0036480527,0.00022043756,0.000069787005,0.0015991752,0.00024628302,0.0000035624687,0.00003619958,0.0011500719],"genre_scores_gemma":[0.9965582,0.00038253918,0.0011537537,0.0001955682,0.0009761216,0.000051408148,0.00007199527,0.000051877,0.0005585393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813026,0.00017640844,0.0003521812,0.00046110066,0.00019995397,0.00068010367],"domain_scores_gemma":[0.99926007,0.00003150759,0.00012148508,0.00029921674,0.00006844564,0.00021929051],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006501987,0.0002919844,0.00027249553,0.000119970515,0.000119376804,0.000038554714,0.0002503944,0.0002896116,0.0003189284],"category_scores_gemma":[0.00015383803,0.0002824217,0.00014440948,0.00025419926,0.00006557295,0.000021972848,0.000108476146,0.00022475512,0.00006891963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014751172,0.0001610043,0.007570865,0.00003295473,0.00004245991,0.000004562463,0.0005894297,0.000081971106,0.9649891,0.00012554553,0.0011149582,0.025139626],"study_design_scores_gemma":[0.00079451577,0.00023051738,0.0009154439,0.00004069641,0.000021911166,0.00003962965,0.00060526375,0.000039581046,0.96401167,0.0006239527,0.03217266,0.00050416554],"about_ca_topic_score_codex":0.000044272085,"about_ca_topic_score_gemma":0.000037211812,"teacher_disagreement_score":0.0310577,"about_ca_system_score_codex":0.000047934926,"about_ca_system_score_gemma":0.000094259776,"threshold_uncertainty_score":0.9999628},"labels":[],"label_agreement":null},{"id":"W2063562477","doi":"10.1016/s1043-2760(00)00260-5","title":"Functional Significance of Oligomerization of G-protein-coupled Receptors","year":2000,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"G protein-coupled receptor; Receptor; Cell biology; Function (biology); Rhodopsin-like receptors; Cell surface receptor; Biology; Chemistry; Biochemistry; Agonist","score_opus":0.02720560838121899,"score_gpt":0.2870037120394534,"score_spread":0.2597981036582344,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063562477","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004417193,0.99430674,0.00017115356,0.000004735017,0.0003559871,0.00019160344,0.00004313529,0.000006090419,0.0005033763],"genre_scores_gemma":[0.0035786764,0.99390733,0.00043588819,0.0000071655513,0.00016352438,0.0000885832,0.00042328503,0.000029813587,0.0013657366],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99839467,0.00016952908,0.00064814714,0.0004253035,0.00010259288,0.0002597593],"domain_scores_gemma":[0.9992695,0.000020168583,0.00036636647,0.00026208375,0.000039885846,0.000042015068],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000119974604,0.00028747835,0.001130222,0.0003819647,0.000027434971,0.0000031769498,0.00015750762,0.00036247494,0.00070161186],"category_scores_gemma":[0.00002639401,0.00025398252,0.00023831788,0.00029051112,0.00016438043,0.0000041508365,0.000058497073,0.0001908405,0.0000023937152],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004719762,0.000056603745,0.0000044241315,0.0006439991,0.00013681942,0.0000016106949,0.000017517064,0.0000139143585,0.019535186,0.0016458499,0.0000306222,0.97786623],"study_design_scores_gemma":[0.0005233314,0.0000945261,0.0000470766,0.00040579698,0.0002238433,0.000022072836,0.000011759659,0.0000031926086,0.018162185,0.00011472824,0.9801278,0.00026365716],"about_ca_topic_score_codex":0.000028939849,"about_ca_topic_score_gemma":0.0000068205427,"teacher_disagreement_score":0.98009723,"about_ca_system_score_codex":0.000006080219,"about_ca_system_score_gemma":0.000081598155,"threshold_uncertainty_score":0.99999124},"labels":[],"label_agreement":null},{"id":"W2063693693","doi":"10.1016/j.ejphar.2011.02.030","title":"Separation and reformation of cell surface dopamine receptor oligomers visualized in cells","year":2011,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"Agonist; G protein-coupled receptor; Receptor; Endogenous agonist; Dopamine; Cell biology; Dopamine receptor D2; Dopamine receptor; Chemistry; Ligand (biochemistry); Biophysics; Biology; Dopamine receptor D1; Neuroscience; Biochemistry","score_opus":0.016613025237429344,"score_gpt":0.2827672298162255,"score_spread":0.2661542045787961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063693693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958719,0.0003403996,0.0020182952,0.00001745854,0.000377477,0.00006504616,0.0000025251704,0.0000015021748,0.0013053801],"genre_scores_gemma":[0.9944467,0.0007052583,0.004573043,0.000071153736,0.000100366466,2.5293454e-7,0.0000051191173,0.000012541276,0.00008557467],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989455,0.0003801658,0.00041554528,0.000088334295,0.00006496926,0.00010548666],"domain_scores_gemma":[0.9994307,0.000007955916,0.0003763406,0.000043996894,0.00009275506,0.000048240207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007883446,0.00008015218,0.00014678562,0.00006854342,0.000016855256,0.00000362462,0.0001008901,0.000032399734,0.00022229226],"category_scores_gemma":[0.0000078787425,0.00007046193,0.000043147476,0.000055933142,0.000034048564,0.000011280641,0.000035760306,0.00009005467,0.000004958966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033179467,0.00006325104,0.000093369854,0.000016726382,0.000020055646,0.000008742253,0.00042004028,0.00011555767,0.9979355,0.000005381681,0.0006209126,0.00036870677],"study_design_scores_gemma":[0.0014348921,0.00077910797,0.00021215678,0.00000968969,0.000018475796,0.00001529706,0.00014134342,0.000071876195,0.9934783,0.0000035339338,0.0037664322,0.00006889647],"about_ca_topic_score_codex":0.0000023532532,"about_ca_topic_score_gemma":4.8953336e-7,"teacher_disagreement_score":0.0044571627,"about_ca_system_score_codex":0.000009002609,"about_ca_system_score_gemma":0.000023247843,"threshold_uncertainty_score":0.28733543},"labels":[],"label_agreement":null},{"id":"W2064253637","doi":"10.1074/jbc.m112.406371","title":"Role of Detergents in Conformational Exchange of a G Protein-coupled Receptor","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Chemistry; Ligand (biochemistry); Micelle; Conformational isomerism; Crystallography; Excited state; Kinetics; Monomer; Stereochemistry; Physical chemistry; Receptor; Molecule; Organic chemistry; Polymer; Physics","score_opus":0.01573814979749294,"score_gpt":0.24020709670091347,"score_spread":0.22446894690342054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064253637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976572,0.0017631905,0.00017154639,0.0000095026235,0.000047422065,0.00006467042,0.000011331472,9.986431e-7,0.00027418343],"genre_scores_gemma":[0.99823165,0.00014727388,0.0013290253,0.000013148315,0.0002158389,0.000004116685,0.000020515805,0.000004658244,0.000033790497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908316,0.000028840073,0.0005184483,0.00006964899,0.00013902482,0.0001608589],"domain_scores_gemma":[0.99921477,0.000011805263,0.00047613683,0.00008167715,0.00013420696,0.00008140548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043218248,0.000092514165,0.00022937203,0.000023327742,0.000010518101,0.0000025182346,0.00015722055,0.00019986519,0.0005617578],"category_scores_gemma":[0.00014958484,0.00006723593,0.00013419974,0.00005507309,0.000046194473,0.000007636719,0.000052994073,0.00010532848,9.652558e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001780492,0.00013285333,0.004778584,0.000045760593,0.000025715692,2.6409623e-7,0.000045594898,0.000005928642,0.99412566,0.000011278685,0.000020042584,0.0006302639],"study_design_scores_gemma":[0.00043674812,0.0002165832,0.0012195357,0.00004651008,0.0000044087647,0.000015907795,0.00015635812,0.000017691495,0.99639904,0.0000686125,0.0013444317,0.00007419721],"about_ca_topic_score_codex":0.0000021032408,"about_ca_topic_score_gemma":1.7228805e-7,"teacher_disagreement_score":0.0035590485,"about_ca_system_score_codex":0.000012618439,"about_ca_system_score_gemma":0.00004168159,"threshold_uncertainty_score":0.6150854},"labels":[],"label_agreement":null},{"id":"W2064335603","doi":"10.1152/physiolgenomics.00070.2012","title":"Functional genomics of the rat neuromedin U receptor 1 reveals a naturally occurring deleterious allele","year":2012,"lang":"en","type":"article","venue":"Physiological Genomics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; AstraZeneca (Canada)","funders":"Pharmaron; AstraZeneca","keywords":"Biology; Receptor; Single-nucleotide polymorphism; Functional genomics; Allele; G protein-coupled receptor; Population; Exon; Genetics; Gene; Genomics; Genotype; Genome; Medicine","score_opus":0.02507819393353483,"score_gpt":0.22954889256308977,"score_spread":0.20447069862955494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064335603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976286,0.00069112895,0.0005544688,0.000039881856,0.0007921424,0.00018828962,0.000024766408,0.000010339312,0.000070326525],"genre_scores_gemma":[0.9964642,0.00016689718,0.0015160652,0.00080304826,0.0008122336,0.000015643252,0.00007670493,0.000020687597,0.00012452375],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988824,0.000099927216,0.00028388482,0.0002702863,0.00011507713,0.00034843592],"domain_scores_gemma":[0.9993524,0.000020931971,0.00016848731,0.00029745782,0.00006229955,0.0000984499],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021400172,0.00017845436,0.00020945251,0.000015121881,0.00011868429,0.000013014285,0.0003226193,0.00017493888,0.0001543496],"category_scores_gemma":[0.0000982058,0.00011947058,0.000209145,0.00006588657,0.000086889064,0.0000060649563,0.00031682625,0.00017171308,0.000017356884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007339152,0.00005239362,0.00033954176,0.000009329909,0.000028188866,9.433093e-8,0.000043707314,0.0003038476,0.996473,0.00023217447,0.0020538906,0.00039044043],"study_design_scores_gemma":[0.00035982212,0.00026190933,0.007897582,0.000008229716,0.000020704749,0.000012920102,0.000076431104,0.000104097926,0.9466039,0.00038384038,0.04397241,0.00029818807],"about_ca_topic_score_codex":0.000003009234,"about_ca_topic_score_gemma":5.9689523e-7,"teacher_disagreement_score":0.049869135,"about_ca_system_score_codex":0.00003176336,"about_ca_system_score_gemma":0.000038458584,"threshold_uncertainty_score":0.48718688},"labels":[],"label_agreement":null},{"id":"W2064504949","doi":"10.1016/j.plasmid.2010.07.002","title":"The p1D4-hrGFP II expression vector: A tool for expressing and purifying visual pigments and other G protein-coupled receptors","year":2010,"lang":"en","type":"article","venue":"Plasmid","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Biology; Molecular biology; Rhodopsin; Transfection; Expression vector; Reporter gene; Heterologous; Heterologous expression; Green fluorescent protein; HEK 293 cells; Bovine genome; Cell biology; Receptor; Gene expression; Cell culture; Gene; Recombinant DNA; Biochemistry; Genetics; Genome","score_opus":0.008427065437384335,"score_gpt":0.25123914448233253,"score_spread":0.2428120790449482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064504949","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966193,0.00035815756,0.002069454,0.000057699493,0.00034904078,0.0004670113,0.000007404105,0.00001377458,0.00005818237],"genre_scores_gemma":[0.9942136,0.000039257495,0.0046625524,0.00007270558,0.0002820294,0.00016396437,0.000012628239,0.000033233275,0.0005200759],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991371,0.000027060869,0.00016463267,0.00031715102,0.000107185595,0.00024685054],"domain_scores_gemma":[0.9996195,0.00003637437,0.00008807324,0.00015332867,0.000034796965,0.000067964145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002888459,0.00015274347,0.00011224037,0.000018656305,0.00060538965,0.000109301975,0.00009809052,0.00015616667,0.000044999317],"category_scores_gemma":[0.00012385657,0.000108360124,0.000042956992,0.000022347664,0.00006569172,0.000008878153,0.00013771921,0.000116241434,7.8597395e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012686157,0.00001988605,0.00019284886,0.000018894994,0.000016142383,1.7205777e-7,0.00010998944,0.0000014920898,0.99520206,0.00009360451,0.00014653188,0.0040715407],"study_design_scores_gemma":[0.000572281,0.00019483095,0.000028725424,0.000041012412,0.0000080433165,0.000004112366,0.00007540006,0.00060650695,0.92316675,0.00015455742,0.074987955,0.00015980746],"about_ca_topic_score_codex":0.0000051281195,"about_ca_topic_score_gemma":0.000008156688,"teacher_disagreement_score":0.074841425,"about_ca_system_score_codex":0.0000041713697,"about_ca_system_score_gemma":0.000022938766,"threshold_uncertainty_score":0.4656229},"labels":[],"label_agreement":null},{"id":"W2064968621","doi":"10.1016/j.bmcl.2010.07.127","title":"Identification of a new biaryl scaffold generating potent renin inhibitors","year":2010,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Renin inhibitor; Scaffold; Bioavailability; Combinatorial chemistry; Renin–angiotensin system; Molecular model; Chemical synthesis; Structure–activity relationship; Ring (chemistry); Drug discovery; Stereochemistry; Pharmacology; In vitro; Biochemistry; Organic chemistry","score_opus":0.006813896079529412,"score_gpt":0.21866471488664807,"score_spread":0.21185081880711865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064968621","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99451244,0.00025246583,0.0035986821,0.0009617569,0.0004998532,0.00010345268,0.00000659666,0.00001936287,0.000045417175],"genre_scores_gemma":[0.9963052,0.000029542662,0.0011717135,0.00033965046,0.0017265249,0.0000056762537,0.00009286709,0.00003206808,0.0002967271],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985563,0.000017452086,0.00047137283,0.00040875256,0.00029703,0.00024908167],"domain_scores_gemma":[0.9990845,0.00000818894,0.00026753623,0.00039886637,0.00006858479,0.0001723554],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000336574,0.00019815302,0.00018554874,0.000029218907,0.00007514606,0.000022909415,0.00027275903,0.00020713099,0.0002341569],"category_scores_gemma":[0.0001597665,0.00018960713,0.00010939908,0.00012801915,0.00008913887,0.0000057336224,0.00007202927,0.0002022833,0.0000063897264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023956753,0.000023146926,0.00019899766,0.000031277785,0.000033597385,0.0000037658751,0.000065667824,0.000009171464,0.99394774,0.0000046056343,0.003798258,0.0018598345],"study_design_scores_gemma":[0.00044542103,0.000028249258,0.00009392906,0.000027583032,0.00003438599,0.000053060518,0.00007456718,0.00007350822,0.997534,0.000010175704,0.0014331854,0.0001919553],"about_ca_topic_score_codex":0.00003507493,"about_ca_topic_score_gemma":0.0000037274158,"teacher_disagreement_score":0.0035862592,"about_ca_system_score_codex":0.000016218104,"about_ca_system_score_gemma":0.0001195444,"threshold_uncertainty_score":0.77319545},"labels":[],"label_agreement":null},{"id":"W2065623515","doi":"10.1210/me.2011-1245","title":"Biasing the Prostaglandin F2α Receptor Responses toward EGFR-Dependent Transactivation of MAPK","year":2012,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Medical University of South Carolina","keywords":"Transactivation; Biology; Cell biology; MAPK/ERK pathway; Receptor; Signal transduction; Kinase; Prostaglandin E2 receptor; Endocrinology; Biochemistry; Transcription factor; Agonist","score_opus":0.02215929924194963,"score_gpt":0.2644557821316848,"score_spread":0.24229648288973518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2065623515","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96005744,0.0019535644,0.036613297,0.00039213858,0.00038883084,0.0002855981,0.000018728095,0.000017511786,0.00027288182],"genre_scores_gemma":[0.99767387,0.00026884384,0.0013601815,0.00022980961,0.00014658862,0.00004408895,0.00005763377,0.000031686184,0.00018731134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985315,0.0002793529,0.0002798858,0.00026154617,0.0001764991,0.0004712193],"domain_scores_gemma":[0.99935037,0.00003207287,0.00012983612,0.0003479541,0.00007334627,0.00006641968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026584463,0.00017760221,0.00018986443,0.00007386317,0.00008378506,0.000013714748,0.00022503434,0.00013930889,0.00012394639],"category_scores_gemma":[0.0001099396,0.00013772587,0.00013045958,0.000094363895,0.000093173,0.000007752552,0.000071898874,0.00013954987,0.000011808993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022723364,0.000061396684,0.00074180175,0.000013745479,0.0000755933,0.0000032536755,0.00025936257,0.000037309463,0.9925955,0.001450754,0.000099142104,0.004434917],"study_design_scores_gemma":[0.000442763,0.0002397431,0.0004381844,0.000009879755,0.000025503383,0.000053188778,0.00030138297,0.000007966733,0.9875879,0.00012017573,0.010617465,0.00015584337],"about_ca_topic_score_codex":0.000027108543,"about_ca_topic_score_gemma":0.0000025016207,"teacher_disagreement_score":0.037616406,"about_ca_system_score_codex":0.000021235768,"about_ca_system_score_gemma":0.00004323708,"threshold_uncertainty_score":0.5616298},"labels":[],"label_agreement":null},{"id":"W2066491797","doi":"10.1016/j.brainres.2006.10.049","title":"Immunohistochemical localization of dopamine receptor subtypes (D1R–D5R) in Alzheimer's disease brain","year":2006,"lang":"en","type":"article","venue":"Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Dopaminergic; Dopamine; Neurotransmitter; Biology; Dopamine receptor; Neuroscience; Dopamine receptor D2; Receptor; Internal medicine; Endocrinology; Central nervous system; Medicine","score_opus":0.024273236539851695,"score_gpt":0.32404457346494914,"score_spread":0.29977133692509744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066491797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833282,0.006101039,0.00791687,0.001289081,0.000099017365,0.00046100863,0.000027833248,0.000015222152,0.0007617158],"genre_scores_gemma":[0.9975831,0.00006535735,0.00045191098,0.000089181005,0.00022766492,0.00004259856,0.00045076958,0.00003210855,0.0010573182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99826777,0.00027491568,0.00031690902,0.00037524165,0.00039248742,0.00037270255],"domain_scores_gemma":[0.9992017,0.0001064653,0.000055829787,0.0003353122,0.00020397252,0.00009670743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011016208,0.0001243061,0.00015531896,0.00015732467,0.0000727254,0.000022000633,0.000255088,0.00015171467,0.00023889328],"category_scores_gemma":[0.0005396115,0.0001237217,0.000074714,0.00033645902,0.00017082194,0.0000057197044,0.00014016683,0.00016655716,0.00001631457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026370012,0.00013533882,0.001540711,0.00002287821,0.0000146995035,0.000003634119,0.000018287315,0.00038410872,0.9781945,0.0004936045,0.01677003,0.0021585554],"study_design_scores_gemma":[0.00064595457,0.0001860013,0.00074518274,0.00004789424,0.0000048210204,0.0000014370788,0.000060239472,0.00081264414,0.95208365,0.0006267383,0.04460681,0.00017860635],"about_ca_topic_score_codex":0.0003394466,"about_ca_topic_score_gemma":0.000045256547,"teacher_disagreement_score":0.02783678,"about_ca_system_score_codex":0.00003163536,"about_ca_system_score_gemma":0.00015503891,"threshold_uncertainty_score":0.50452244},"labels":[],"label_agreement":null},{"id":"W2066630799","doi":"10.1155/2012/210324","title":"Dopamine<mml:math xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"><mml:mrow><mml:msub><mml:mtext>D</mml:mtext><mml:mtext>2</mml:mtext></mml:msub></mml:mrow></mml:math>Receptor-Mediated Heterologous Sensitization of AC5 Requires Signalosome Assembly","year":2012,"lang":"lv","type":"article","venue":"Journal of Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Institute of Mental Health; Purdue University","keywords":"Algorithm; Artificial intelligence; Computer science","score_opus":0.016795088583947026,"score_gpt":0.23878468071185296,"score_spread":0.22198959212790595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066630799","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97651905,0.0032518578,0.008458691,0.0005092129,0.0034917193,0.00007602776,0.00017327291,0.00005412873,0.0074660513],"genre_scores_gemma":[0.9897464,0.0028198496,0.0014238526,0.0004412429,0.004222572,0.000085815125,0.00077750057,0.00033224045,0.00015053344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9934141,0.0005467578,0.0020577325,0.00093312137,0.0016128828,0.0014354204],"domain_scores_gemma":[0.995143,0.0003869742,0.0024879768,0.00079680735,0.0004273584,0.00075788813],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002109231,0.0007232365,0.0004854685,0.00043066533,0.0007000821,0.00041035886,0.00082374923,0.0020214291,0.03414686],"category_scores_gemma":[0.00042245764,0.0010511428,0.0014392551,0.0006112539,0.0006347696,0.0005471582,0.0002624883,0.0012096759,0.00033888154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022532784,0.000503469,0.000025804957,0.0007444897,0.0015243406,0.00021753342,0.0012464724,0.0038093764,0.92392564,0.05430272,0.007900244,0.0035466228],"study_design_scores_gemma":[0.0017388597,0.003520168,0.00008871115,0.00074187684,0.0010114225,0.0015708281,0.0010919016,0.022682732,0.9646609,0.00006588591,0.0019382561,0.00088849576],"about_ca_topic_score_codex":0.00021522329,"about_ca_topic_score_gemma":0.00009533077,"teacher_disagreement_score":0.054236833,"about_ca_system_score_codex":0.000031196898,"about_ca_system_score_gemma":0.00072632113,"threshold_uncertainty_score":0.99927413},"labels":[],"label_agreement":null},{"id":"W2066809615","doi":"10.1038/sj.bjp.0705787","title":"Functional M<sub>3</sub> muscarinic acetylcholine receptors in mammalian hearts","year":2004,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Muscarinic acetylcholine receptor; Muscarinic acetylcholine receptor M3; Acetylcholine; Receptor; Muscarinic acetylcholine receptor M2; Muscarinic acetylcholine receptor M4; Cholinergic; Neuroscience; Medicine; Internal medicine; Parasympathetic nervous system; Biology; Autonomic nervous system; Endocrinology; Heart rate; Blood pressure","score_opus":0.024069760725360347,"score_gpt":0.3006591491832798,"score_spread":0.27658938845791947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066809615","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00998352,0.98506385,0.00023690982,0.00004714047,0.004248506,0.00034238538,0.00003497352,0.0000060717443,0.00003663452],"genre_scores_gemma":[0.0027935042,0.99374,0.00026773952,0.00018805228,0.0026054604,0.000029406048,0.00017142293,0.000083128245,0.00012123959],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970711,0.00045074953,0.0012916488,0.0004467618,0.00025913975,0.00048063407],"domain_scores_gemma":[0.9986137,0.000038897935,0.0008428864,0.00010340516,0.00020113288,0.0001999712],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00088823156,0.0003810335,0.0012854849,0.00028336057,0.00008151052,0.00004857932,0.00037714842,0.00069090625,0.0007348186],"category_scores_gemma":[0.000072466515,0.00042782325,0.0008182695,0.00023635887,0.000089224064,0.000012958521,0.00013745151,0.0010656889,0.000028892333],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008346069,0.00025516356,0.0000021396377,0.0015819834,0.00039467105,0.0007353492,0.000009929524,0.00016603325,0.09003557,0.000006320781,0.01933796,0.8873914],"study_design_scores_gemma":[0.001768043,0.00039679834,0.0000056898316,0.0038746942,0.00040948574,0.010174423,0.000011243302,7.577085e-7,0.0430555,0.00003271398,0.93983185,0.0004388004],"about_ca_topic_score_codex":0.000013643728,"about_ca_topic_score_gemma":0.00003222594,"teacher_disagreement_score":0.9204939,"about_ca_system_score_codex":0.00017214124,"about_ca_system_score_gemma":0.0009294187,"threshold_uncertainty_score":0.9998174},"labels":[],"label_agreement":null},{"id":"W2066812847","doi":"10.1073/pnas.0704257104","title":"Quantification of dynamic protein complexes using <i>Renilla</i> luciferase fragment complementation applied to protein kinase A activities <i>in vivo</i>","year":2007,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":188,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Effector; Luciferase; Protein-fragment complementation assay; Protein kinase A; Biology; Signal transduction; Complementation; Receptor; Cell biology; Second messenger system; Kinase; Biochemistry; Transfection; Phenotype; Gene","score_opus":0.032865068843972924,"score_gpt":0.3150130148640943,"score_spread":0.28214794602012133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066812847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99795043,0.000029614592,0.00090282015,0.0001452543,0.0000084634385,0.0006570859,0.000023048677,0.0000025535383,0.00028070164],"genre_scores_gemma":[0.9884395,0.000002113495,0.011414443,0.00006583529,0.000023198274,0.00002567143,0.000001159656,0.0000048566285,0.000023214414],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867564,0.000007543858,0.00038375353,0.00023124894,0.00056091446,0.0001409241],"domain_scores_gemma":[0.9994158,0.00001444878,0.00039858196,0.000012578524,0.00013202961,0.00002656657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013382962,0.00008913091,0.00013062725,0.00014664269,0.00009704358,0.000012489535,0.0002949105,0.000057917252,0.000008452541],"category_scores_gemma":[0.00006684025,0.000072241724,0.000044544533,0.0003734484,0.00019096863,0.000020137517,0.00008058361,0.000055369368,1.02001664e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000759678,0.00005412918,0.00018745838,0.00006346501,0.0000063465186,2.4428637e-9,0.000096996606,0.00043423683,0.9879063,0.010910705,0.00001058151,0.0002538578],"study_design_scores_gemma":[0.00019335547,0.00008001733,0.000931715,0.00009718878,0.0000037910215,7.107651e-7,0.0005863017,0.0005498247,0.9945179,0.002922472,0.000038749877,0.00007793173],"about_ca_topic_score_codex":0.000019747891,"about_ca_topic_score_gemma":0.0000020234709,"teacher_disagreement_score":0.010511623,"about_ca_system_score_codex":0.000032834127,"about_ca_system_score_gemma":0.000030865212,"threshold_uncertainty_score":0.29459321},"labels":[],"label_agreement":null},{"id":"W2066874540","doi":"10.1016/j.neures.2009.09.312","title":"Cloning and characterization of Aplysia 5HT GPCRs involved in the translocation of PKC Apl II","year":2009,"lang":"en","type":"article","venue":"Neuroscience Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"G protein-coupled receptor; Receptor; Biology; Enzyme-linked receptor; 5-HT5A receptor; Prostaglandin E2 receptor; Molecular biology; Chinese hamster ovary cell; Protease-activated receptor 2; Adenylyl cyclase; Biochemistry; Chemistry; Agonist","score_opus":0.05171615877583231,"score_gpt":0.33959245113397873,"score_spread":0.28787629235814644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066874540","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982354,0.000065522494,0.0012001924,0.00029285823,0.000022501177,0.00013702233,0.0000016395106,0.0000011198568,0.00004376643],"genre_scores_gemma":[0.9994816,0.00033091172,0.000059829672,0.00007115794,0.000019154162,0.000004522553,0.000007207422,0.0000025179513,0.000023073684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991238,0.00014403992,0.00013775533,0.00017581928,0.00027373803,0.00014481146],"domain_scores_gemma":[0.9997121,0.0000133461235,0.000039280792,0.00013781723,0.0000756583,0.000021781674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010844319,0.00004115877,0.00006430821,0.00008117885,0.0000913064,0.000015086032,0.00019230918,0.000041466523,0.0000019580839],"category_scores_gemma":[0.00010653884,0.000031292988,0.000016908847,0.00035732464,0.00011414468,0.00000822814,0.000027279104,0.000086265456,7.5411116e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016351923,0.00003593418,0.00030071585,0.000006527617,2.6230526e-7,2.9362252e-7,0.00031963008,0.000012038573,0.99493104,0.0004202994,0.0000022963247,0.003954632],"study_design_scores_gemma":[0.00011055629,0.00045164488,0.013252938,0.0000149617845,6.708961e-7,0.0000012013522,0.00012803946,0.0010683616,0.9846339,0.00015736606,0.00015089939,0.000029466286],"about_ca_topic_score_codex":0.000011978133,"about_ca_topic_score_gemma":0.0000038772864,"teacher_disagreement_score":0.0129522225,"about_ca_system_score_codex":0.0000030082615,"about_ca_system_score_gemma":0.000045305038,"threshold_uncertainty_score":0.1276091},"labels":[],"label_agreement":null},{"id":"W2067132128","doi":"10.1038/sj.jcbfm.9600161","title":"Sequential versus Nonsequential Measurement of Density and Affinity of Dopamine D2 Receptors with [<sup>11</sup>C]Raclopride: 2: Effects of DAT Inhibitors","year":2005,"lang":"en","type":"article","venue":"Journal of Cerebral Blood Flow & Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; TRIUMF","funders":"TRIUMF","keywords":"Raclopride; Dopamine; Dopamine receptor D2; Receptor; Neuroscience; Medicine; Dopamine receptor; Internal medicine; Pharmacology; Endocrinology; Chemistry; Psychology","score_opus":0.009200307018429082,"score_gpt":0.2159423148816201,"score_spread":0.20674200786319102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067132128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934873,0.0029833054,0.0025879508,0.000043092867,0.0006593033,0.00020113807,0.000013534571,0.0000036984347,0.000020675303],"genre_scores_gemma":[0.9867161,0.0004171986,0.011878293,0.000016834407,0.000913911,0.0000020221926,0.00001020111,0.000030472554,0.00001500235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99752086,0.00022594086,0.00091482495,0.00026884655,0.00079517864,0.00027433492],"domain_scores_gemma":[0.99772006,0.000041446438,0.0009956827,0.000279263,0.0007781789,0.00018536093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000938477,0.00028895464,0.00078340934,0.0001568462,0.000056595298,0.000017348297,0.00024355261,0.00020556898,0.000054862096],"category_scores_gemma":[0.00025452,0.00022956602,0.00030213312,0.00015573823,0.00017643766,0.00003927624,0.0001241013,0.0002290784,3.8108462e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014440867,0.0003485929,0.00097535097,0.00015256999,0.0007765977,0.0000075277444,0.0001576455,0.0011380407,0.9908193,0.00004615763,0.00011517725,0.0040189927],"study_design_scores_gemma":[0.006185362,0.0012509783,0.00048047095,0.00016617404,0.0009043695,0.00007554984,0.00007468682,0.00008323444,0.9891877,0.000014918444,0.00136639,0.00021016774],"about_ca_topic_score_codex":0.000046136454,"about_ca_topic_score_gemma":0.000049597456,"teacher_disagreement_score":0.009290342,"about_ca_system_score_codex":0.000018934325,"about_ca_system_score_gemma":0.00024467648,"threshold_uncertainty_score":0.9361431},"labels":[],"label_agreement":null},{"id":"W2067150585","doi":"10.3791/2432","title":"Hyperinsulinemic-Euglycemic Clamp in the Conscious Rat","year":2011,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Genome Canada; Canadian Diabetes Association; Heart and Stroke Foundation of Canada","keywords":"Clamp; Internal medicine; Insulin; Endocrinology; Medicine","score_opus":0.0386584591444005,"score_gpt":0.3739916147911482,"score_spread":0.3353331556467477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067150585","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956481,0.0018766423,0.001021899,0.000019704732,0.00045693916,0.00010295766,9.3134355e-7,0.0000023147347,0.00087051734],"genre_scores_gemma":[0.9963617,0.00031347727,0.0025738177,0.00045013026,0.00020129586,0.0000064700976,0.0000035806556,0.000015347747,0.000074224015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896204,0.00012196125,0.00041479015,0.00012435681,0.00019758921,0.00017923028],"domain_scores_gemma":[0.9994583,0.000009514591,0.00023110099,0.00016822977,0.00007564112,0.00005719949],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042533624,0.00012371225,0.00018525324,0.00006225437,0.000042450858,0.000019359853,0.00032567937,0.00009725025,0.00017881664],"category_scores_gemma":[0.000045884422,0.00008291303,0.00012569767,0.00007358022,0.00003772681,0.000007127907,0.00004225684,0.00012988216,0.0000058860846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046229613,0.00016859175,0.00039448048,0.000002846327,0.00003315298,0.000028548366,0.0014174212,0.0000025010931,0.99632275,0.00011122566,0.0007246922,0.000331474],"study_design_scores_gemma":[0.0018999792,0.0006028194,0.00009000277,0.00002359736,0.000011019764,0.00015480552,0.0014469466,0.000010525351,0.9856094,0.00014932103,0.00988885,0.00011273444],"about_ca_topic_score_codex":0.000011648071,"about_ca_topic_score_gemma":0.0000014897325,"teacher_disagreement_score":0.010713371,"about_ca_system_score_codex":0.0000151635195,"about_ca_system_score_gemma":0.000057445868,"threshold_uncertainty_score":0.33810952},"labels":[],"label_agreement":null},{"id":"W2067166210","doi":"10.1517/17460441.2011.586691","title":"Ligand functional selectivity and quantitative pharmacology at G protein-coupled receptors","year":2011,"lang":"en","type":"article","venue":"Expert Opinion on Drug Discovery","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Functional selectivity; Drug discovery; Terminology; G protein-coupled receptor; Computational biology; Computer science; Neuroscience; Biology; Bioinformatics; Receptor; Genetics","score_opus":0.02961676921387865,"score_gpt":0.2772790397789788,"score_spread":0.24766227056510012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067166210","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993478,0.00201411,0.0020681215,0.00011385237,0.0014078998,0.0003065321,0.000010006035,0.00001905907,0.00058238936],"genre_scores_gemma":[0.99518144,0.0010363488,0.0005563425,0.00038550855,0.0004291629,0.000115571835,0.00009215549,0.00002971986,0.0021737209],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890804,0.00009634613,0.00016339026,0.00047208762,0.00013537526,0.00022478672],"domain_scores_gemma":[0.99962264,0.000022052189,0.00008827296,0.00013614146,0.00004775841,0.000083120525],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016821864,0.00019463494,0.00016026183,0.00004894145,0.0001777607,0.00002359933,0.00008316508,0.0001120503,0.00041138192],"category_scores_gemma":[0.00003068858,0.0001708038,0.00007742096,0.000060962397,0.00008293518,0.000021102072,0.00010697862,0.0000965976,0.000019261977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009590929,0.00013645235,0.00019017557,0.000006481542,0.000069975256,0.0000010357247,0.00041182883,0.000014331944,0.9879781,0.0007138257,0.009188292,0.00033040106],"study_design_scores_gemma":[0.0006835848,0.0005293207,0.00029605822,0.000019456755,0.0000024780368,0.000005824934,0.00019956254,0.00009921126,0.97762805,0.0001277067,0.020173868,0.00023488654],"about_ca_topic_score_codex":0.000050135804,"about_ca_topic_score_gemma":0.000011389339,"teacher_disagreement_score":0.0109855775,"about_ca_system_score_codex":0.000032362077,"about_ca_system_score_gemma":0.00005364935,"threshold_uncertainty_score":0.6965177},"labels":[],"label_agreement":null},{"id":"W2067224374","doi":"10.1016/s0968-0896(99)00266-7","title":"The design and synthesis of a potent angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone angiotensin II","year":2000,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; Stereochemistry; Angiotensin II; Cyclic peptide; Nuclear magnetic resonance spectroscopy; Ring (chemistry); Peptide; Receptor; Biochemistry; Organic chemistry","score_opus":0.0073625397212979515,"score_gpt":0.19866724316701484,"score_spread":0.1913047034457169,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067224374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99258703,0.0036966868,0.0006731898,0.0024977047,0.000084860054,0.00027612402,0.000015579159,0.000008226017,0.00016059807],"genre_scores_gemma":[0.99783874,0.001170215,0.0002441427,0.00022083515,0.00020257622,0.000008844245,0.000012687553,0.000019656864,0.00028231982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869365,0.00009969586,0.00043301756,0.0002354342,0.00028961507,0.00024857745],"domain_scores_gemma":[0.99892735,0.000092322516,0.0003126431,0.00046688927,0.00012883774,0.00007195867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007188112,0.00020091362,0.00024885687,0.000009778287,0.00044327579,0.000012829687,0.00034298093,0.00020568034,0.00006914578],"category_scores_gemma":[0.00022999436,0.00010522313,0.00013077602,0.00013545276,0.00037431362,0.0000060163925,0.00015096398,0.0001718894,0.0000012693177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015067222,0.000031047355,0.000021513299,0.000017988285,0.000091572714,4.4273034e-7,0.00022024823,0.000021251191,0.99098307,0.0000064887217,0.0017821093,0.0066735717],"study_design_scores_gemma":[0.00044760582,0.00013401834,0.0006155944,0.00010332456,0.00009422006,0.000056981626,0.00048598665,0.00036955017,0.99204206,0.000022604116,0.0054985844,0.00012943694],"about_ca_topic_score_codex":0.00004090286,"about_ca_topic_score_gemma":0.000002899418,"teacher_disagreement_score":0.0065441346,"about_ca_system_score_codex":0.000019201905,"about_ca_system_score_gemma":0.00007437774,"threshold_uncertainty_score":0.4290875},"labels":[],"label_agreement":null},{"id":"W2067423390","doi":"10.1159/000138457","title":"Classification of Angiotensin Receptors in Rat Isolated Uterus, Portal Vein, and Aorta with the Novel Competitive Antagonist Sarmesin","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Tachyphylaxis; Endocrinology; Angiotensin II; Internal medicine; Receptor; Uterus; Renin–angiotensin system; Aorta; Antagonist; Angiotensin II receptor type 1; Biology; Chemistry; Medicine; Blood pressure","score_opus":0.015645949018622214,"score_gpt":0.26056574219304596,"score_spread":0.24491979317442375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067423390","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99708915,0.0003500238,0.0012782539,0.00064749963,0.00020411104,0.00020526508,0.000010938182,0.0000056336885,0.00020910613],"genre_scores_gemma":[0.9985618,0.00034465254,0.00044496896,0.00033201696,0.00008953647,0.000011735174,0.00007032324,0.000014002426,0.00013098141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927825,0.00007093387,0.0001778339,0.00024075563,0.00006664024,0.00016557184],"domain_scores_gemma":[0.9996498,0.000020235393,0.0001167685,0.00009661688,0.00007724256,0.000039303395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012621802,0.000116839656,0.0001562843,0.000041206255,0.00008004919,0.000004895021,0.000092148475,0.00009528558,0.000087850196],"category_scores_gemma":[0.0000062296563,0.000086095344,0.000030033774,0.00010297779,0.00022857511,0.0000045756033,0.00003804205,0.000105516156,0.0000010895286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027091528,0.00007877936,0.0027444633,0.0000046155465,0.00004783769,0.000010098376,0.0001593054,0.000024700514,0.9945579,0.00014809877,0.001732096,0.00022115592],"study_design_scores_gemma":[0.0013669139,0.00045795954,0.0060099727,0.000008497317,0.000032762375,0.00013477972,0.0002641383,0.0006032528,0.9730837,0.000004912213,0.017877668,0.00015543803],"about_ca_topic_score_codex":0.00003455925,"about_ca_topic_score_gemma":0.000049015278,"teacher_disagreement_score":0.02147423,"about_ca_system_score_codex":0.000008434222,"about_ca_system_score_gemma":0.00006243025,"threshold_uncertainty_score":0.35108662},"labels":[],"label_agreement":null},{"id":"W2067534797","doi":"10.1074/jbc.m111.267815","title":"Regulation of β2-Adrenergic Receptor Maturation and Anterograde Trafficking by an Interaction with Rab Geranylgeranyltransferase","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Rab; Geranylgeranylation; Cell biology; GTPase; Prenylation; Biology; Endoplasmic reticulum; Transport protein; Biochemistry","score_opus":0.019259695281980134,"score_gpt":0.22875441345654388,"score_spread":0.20949471817456375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067534797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933504,0.00039795993,0.0060503306,0.000016185852,0.000056388046,0.000045081957,0.000006802774,0.000004806755,0.000072046765],"genre_scores_gemma":[0.9968575,0.00031264086,0.0025609531,0.000021643284,0.00015337826,0.0000015920382,0.0000685045,0.000008998453,0.000014786933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992326,0.000050214,0.00034269172,0.00016720846,0.00009940596,0.00010787765],"domain_scores_gemma":[0.99940974,0.000009516433,0.00028249857,0.00008796863,0.00012620613,0.000084056745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020127681,0.00012419611,0.00018942257,0.000019191772,0.000037166992,0.00001650265,0.00009037465,0.0001879718,0.00013895852],"category_scores_gemma":[0.000022617789,0.00008446244,0.0000703294,0.000045360386,0.00006628381,0.000020863074,0.000010187405,0.00012650872,1.2140627e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010838804,0.0001091824,0.0004630432,0.000018795157,0.00003842376,0.0000016030739,0.00009826297,0.000024608456,0.9956812,0.0000043308555,0.000032499272,0.0024441686],"study_design_scores_gemma":[0.00052778504,0.0010782636,0.00079045165,0.000049734004,0.000018075521,0.00012573533,0.00020829236,0.00006249818,0.9967304,0.000030505294,0.00026738425,0.00011089081],"about_ca_topic_score_codex":0.0000031002803,"about_ca_topic_score_gemma":5.305391e-7,"teacher_disagreement_score":0.0035071052,"about_ca_system_score_codex":0.000009033542,"about_ca_system_score_gemma":0.000017281098,"threshold_uncertainty_score":0.34442782},"labels":[],"label_agreement":null},{"id":"W2067576733","doi":"10.1016/j.taap.2008.01.028","title":"Receptor-independent, vacuolar ATPase-mediated cellular uptake of histamine receptor-1 ligands: Possible origin of pharmacological distortions and side effects","year":2008,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"","keywords":"Histamine; Histamine H1 receptor; Pharmacology; Chemistry; Agonist; Capsazepine; Pyrilamine; Bafilomycin; Histamine receptor; Receptor; Histamine H2 receptor; Biochemistry; Biology; Antagonist; TRPV1","score_opus":0.014551086583464884,"score_gpt":0.2553484591546838,"score_spread":0.24079737257121892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067576733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951734,0.0023332431,0.0006424747,0.000092730785,0.00055082556,0.00056521094,0.00007015633,0.000028743098,0.00054322474],"genre_scores_gemma":[0.99526376,0.0024996323,0.0010186041,0.0003413984,0.00023729078,0.00011354774,0.00018789605,0.00003181195,0.00030604593],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981124,0.00013782208,0.0005803831,0.0005926901,0.000142313,0.00043443832],"domain_scores_gemma":[0.9990456,0.00015569174,0.00032162658,0.00016133333,0.000088638044,0.00022708085],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034684382,0.00031805065,0.0006107153,0.00012303771,0.00021117768,0.000004469926,0.00020522531,0.00053806975,0.0005003355],"category_scores_gemma":[0.000041836214,0.00030147485,0.00009889454,0.00016423035,0.0005954722,0.000009057835,0.00018339959,0.00030566464,0.000009441648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071985525,0.00038909004,0.0007098839,0.00008322839,0.0003098885,0.00001559333,0.00012617448,0.000029990473,0.9941728,0.00047883138,0.0019571914,0.001007465],"study_design_scores_gemma":[0.0030748583,0.0010360323,0.0011325611,0.000008484783,0.00019079063,0.0000352469,0.000056069377,0.000044801523,0.98201936,0.00007330088,0.012055413,0.00027309216],"about_ca_topic_score_codex":0.000007685709,"about_ca_topic_score_gemma":0.000003036506,"teacher_disagreement_score":0.012153459,"about_ca_system_score_codex":0.000026469994,"about_ca_system_score_gemma":0.00012440413,"threshold_uncertainty_score":0.99994373},"labels":[],"label_agreement":null},{"id":"W2068050893","doi":"10.1371/journal.pone.0056174","title":"β-Arrestin2 Regulates Lysophosphatidic Acid-Induced Human Breast Tumor Cell Migration and Invasion via Rap1 and IQGAP1","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Lysophosphatidic acid; Invadopodia; Cancer research; Cortactin; Cell migration; IQGAP1; Cancer cell; Biology; Metastasis; RAC1; Breast cancer; Actin cytoskeleton; Cell biology; Cancer; Receptor; Scaffold protein; Internal medicine; Medicine; Cell; Signal transduction; Cytoskeleton","score_opus":0.01594994445218598,"score_gpt":0.19244395168859707,"score_spread":0.1764940072364111,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068050893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99839795,0.0009442211,0.000085341744,0.00012010719,0.000022163576,0.00033902552,0.0000036087597,0.000016405203,0.000071175215],"genre_scores_gemma":[0.9979101,0.00012376894,0.001431167,0.0001051224,0.00012217688,0.00004717097,0.0000694679,0.00002186367,0.00016920874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919516,0.0000356697,0.00016656135,0.0003115254,0.00012267832,0.0001683849],"domain_scores_gemma":[0.9995478,0.000007404673,0.00008360216,0.00017596773,0.00007826686,0.00010699514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009469098,0.0001442178,0.00015146221,0.000031806612,0.00013549847,0.00006165237,0.00006617465,0.00010185805,0.00010464553],"category_scores_gemma":[0.000016703683,0.000132399,0.000025197343,0.000042658274,0.00003132626,0.000011965223,0.00007123117,0.000064397995,0.000010938089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012001951,0.00012534717,0.0026042417,0.000048598074,0.000026707361,9.084843e-7,0.000049853643,3.9192537e-7,0.9961923,0.000010607398,0.00006491864,0.00086416927],"study_design_scores_gemma":[0.00038481716,0.00026839646,0.0047220043,0.00005710139,0.00003420191,0.000009495424,0.00004230289,0.00029585895,0.9936642,0.00034056554,0.000016108372,0.0001649477],"about_ca_topic_score_codex":0.00013580968,"about_ca_topic_score_gemma":0.000027500002,"teacher_disagreement_score":0.0025280542,"about_ca_system_score_codex":0.000005762982,"about_ca_system_score_gemma":0.000012987656,"threshold_uncertainty_score":0.53990746},"labels":[],"label_agreement":null},{"id":"W2068584231","doi":"10.1016/j.yexcr.2005.04.015","title":"The constitutively active N111G-AT1 receptor for angiotensin II modifies the morphology and cytoskeletal organization of HEK-293 cells","year":2005,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Cytoskeleton; HEK 293 cells; Angiotensin II receptor type 1; Receptor; Angiotensin II; Genetics; Cell","score_opus":0.025879485935915394,"score_gpt":0.31643062281517426,"score_spread":0.2905511368792589,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068584231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954206,0.0016406085,0.001227898,0.00037758207,0.00011378758,0.000545061,0.000028139975,0.000004846422,0.00064149685],"genre_scores_gemma":[0.9970693,0.0003294637,0.0010739629,0.000048940758,0.00017189102,0.000040282728,0.00004351708,0.000019748648,0.0012028996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894184,0.00014669611,0.00015996252,0.0002657772,0.00019475319,0.0002909894],"domain_scores_gemma":[0.9993327,0.00010693721,0.000058772996,0.0001950891,0.00025258822,0.000053899592],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046294404,0.00011082453,0.00010910417,0.000031753294,0.0007153178,0.00003476551,0.00020594588,0.000111939444,0.00008055749],"category_scores_gemma":[0.00006901081,0.00007230523,0.000051297317,0.00010444725,0.00055953074,0.000007607324,0.00025732088,0.0001209968,0.000007806874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015329615,0.00007388705,0.00000903557,0.000004136684,0.000024548852,2.6019183e-7,0.00054909114,0.000028586335,0.993621,0.0010411404,0.0034463077,0.0010487309],"study_design_scores_gemma":[0.00042942673,0.0005211909,0.000010036759,0.0000040377795,0.0000035102405,0.0000036642548,0.0019458786,0.0000859887,0.9695691,0.0000402785,0.027305005,0.00008189821],"about_ca_topic_score_codex":0.000027581986,"about_ca_topic_score_gemma":0.0000033042713,"teacher_disagreement_score":0.024051894,"about_ca_system_score_codex":0.00003083525,"about_ca_system_score_gemma":0.00008651814,"threshold_uncertainty_score":0.55017185},"labels":[],"label_agreement":null},{"id":"W2068584519","doi":"10.1016/j.apradiso.2008.12.015","title":"An improved radiosynthesis of the muscarinic M2 radiopharmaceutical, [18F]FP-TZTP","year":2008,"lang":"en","type":"article","venue":"Applied Radiation and Isotopes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Radiosynthesis; Chemistry; Radioligand; Cryptand; Radiochemistry; Muscarinic acetylcholine receptor; Nucleophile; Agonist; Acetylcholine receptor; Nuclear chemistry; Positron emission tomography; Yield (engineering); Receptor; Stereochemistry; Nuclear medicine; Organic chemistry; Biochemistry","score_opus":0.009733170504249372,"score_gpt":0.23428544243863092,"score_spread":0.22455227193438154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068584519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971566,0.0006564286,0.0009904028,0.00008619593,0.00011167111,0.00026032163,0.000007269401,0.000011053376,0.00072004343],"genre_scores_gemma":[0.99771214,0.0010359898,0.00058642746,0.00036556716,0.00015461468,0.000023843591,0.000015211128,0.000015345828,0.0000908927],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993057,0.000044734443,0.00018421444,0.00023402163,0.000091882146,0.00013939796],"domain_scores_gemma":[0.9995496,0.000015419926,0.0000876461,0.00024909156,0.000024718263,0.00007349815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001355174,0.000109094435,0.00013486725,0.000025040878,0.0001592101,0.000013223758,0.00015104206,0.000088136665,0.00006377191],"category_scores_gemma":[0.00001970985,0.00008433872,0.00006406901,0.00007020199,0.00009696654,0.000005333101,0.000034592384,0.0000652496,0.0000018548399],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003995517,0.00003762528,0.00047374112,0.000008158511,0.000029297196,2.0972027e-7,0.00012027378,0.000041675416,0.97968686,0.00044728394,0.00015744817,0.018957464],"study_design_scores_gemma":[0.00057152327,0.00009002312,0.005295595,0.0000031710663,0.000023734407,0.00001126737,0.00008828919,0.00095759623,0.976126,0.00006177491,0.016626704,0.00014430626],"about_ca_topic_score_codex":0.000014862086,"about_ca_topic_score_gemma":0.000002290503,"teacher_disagreement_score":0.01881316,"about_ca_system_score_codex":0.0000061745577,"about_ca_system_score_gemma":0.000040286664,"threshold_uncertainty_score":0.34392333},"labels":[],"label_agreement":null},{"id":"W2068781216","doi":"10.1016/j.pharmthera.2010.04.007","title":"Broad-spectrum amino acid-sensing class C G-protein coupled receptors: Molecular mechanisms, physiological significance and options for drug development","year":2010,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Medical Research Council; National Health and Medical Research Council","keywords":"Receptor; Broad spectrum; Drug development; G protein-coupled receptor; Amino acid; Biology; Computational biology; Cell biology; Biochemistry; Drug; Chemistry; Pharmacology; Combinatorial chemistry","score_opus":0.04237537587820275,"score_gpt":0.328150142341898,"score_spread":0.28577476646369526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068781216","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003542912,0.9468888,0.04524595,0.00017742248,0.0013315554,0.002669306,0.000058493257,0.00006925063,0.000016298123],"genre_scores_gemma":[0.0015345131,0.9633548,0.03146977,0.0012058598,0.00062672485,0.0006450269,0.00063120626,0.0001784172,0.00035366413],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99683315,0.00036984516,0.0007366714,0.0011069215,0.00020508986,0.00074829697],"domain_scores_gemma":[0.99870974,0.000070020615,0.00049433706,0.00037410588,0.00015530491,0.00019650852],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005822004,0.00079561345,0.0012315328,0.0001162046,0.00037741428,0.00006671344,0.00047633072,0.0011222026,0.000104365965],"category_scores_gemma":[0.000012650822,0.0007020744,0.0004192534,0.00014271845,0.00021518265,0.0000068766494,0.00023255074,0.00081154215,0.000013418418],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045785764,0.000098415156,2.7361073e-8,0.0006001482,0.0006636339,0.000004950367,0.000030564966,0.0000049092027,0.8536153,0.00052581733,0.00013742197,0.14427306],"study_design_scores_gemma":[0.00044206146,0.0001730917,8.707238e-8,0.00019184928,0.0007449844,0.00001799173,0.000017228645,0.00012813603,0.35171598,0.0003892063,0.645626,0.00055337575],"about_ca_topic_score_codex":0.0000032318715,"about_ca_topic_score_gemma":0.00000715989,"teacher_disagreement_score":0.6454886,"about_ca_system_score_codex":0.00008182333,"about_ca_system_score_gemma":0.00045985484,"threshold_uncertainty_score":0.999543},"labels":[],"label_agreement":null},{"id":"W2068855429","doi":"10.1074/jbc.m503438200","title":"The Intracellular Trafficking of the G Protein-coupled Receptor TPβ Depends on a Direct Interaction with Rab11","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Intracellular; Chemistry; Cell biology; Biophysics; Biology; Biochemistry","score_opus":0.010661287467438088,"score_gpt":0.2235193429465646,"score_spread":0.2128580554791265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068855429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99799,0.0005555296,0.0003842566,0.00034909975,0.0000932491,0.00010052002,0.0000022286006,0.000003813039,0.0005212745],"genre_scores_gemma":[0.9985249,0.00014709162,0.00045987533,0.000049203645,0.0005449949,0.0000058337287,0.000005179261,0.000010168462,0.00025272268],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902767,0.00007156529,0.00037627722,0.00015819314,0.00019577531,0.00017053998],"domain_scores_gemma":[0.9990552,0.000048408667,0.0005070521,0.00019526487,0.00013630847,0.00005777969],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004869285,0.00014298783,0.00018895234,0.000009261802,0.000119198594,0.00002542722,0.00032961357,0.00017596864,0.00009612279],"category_scores_gemma":[0.00021883039,0.00006201895,0.00019804461,0.000069327805,0.000096324475,0.00000485928,0.000047352718,0.00031346592,0.0000010279947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006185207,0.00007907349,0.00007164017,0.0000079685315,0.000063816915,0.0000015404181,0.000017849745,0.00038001477,0.99445045,0.000009347592,0.00006262023,0.0042371745],"study_design_scores_gemma":[0.00037666052,0.0005069039,0.00003686746,0.00008650967,0.00001332243,0.00005538104,0.00013786965,0.000081413986,0.9794768,0.000010837192,0.019125512,0.00009194046],"about_ca_topic_score_codex":9.628363e-7,"about_ca_topic_score_gemma":0.0000014191935,"teacher_disagreement_score":0.019062892,"about_ca_system_score_codex":0.000030244782,"about_ca_system_score_gemma":0.00005502357,"threshold_uncertainty_score":0.25290596},"labels":[],"label_agreement":null},{"id":"W2068986787","doi":"10.2298/abs070343pt","title":"Effects of SRIH-14 on ACTH cells in male rats","year":2007,"lang":"en","type":"article","venue":"Archives of Biological Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Internal medicine; Endocrinology; Biology; Chemistry; Medicine","score_opus":0.013763264951912876,"score_gpt":0.2575941394999975,"score_spread":0.2438308745480846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068986787","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99448633,0.00019022766,0.0012238855,0.000012971184,0.000067782225,0.000090590016,0.0000029817263,0.0000019691447,0.0039232676],"genre_scores_gemma":[0.99692035,0.0001765107,0.0027692541,0.000057614987,0.000029463981,0.0000017044172,0.000002812934,0.000001553494,0.000040735955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992935,0.000058694633,0.00016066288,0.00021394482,0.000084830805,0.00018838372],"domain_scores_gemma":[0.99961007,0.00020789087,0.000069554684,0.000066249435,0.0000066040507,0.000039629864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003591501,0.000069704445,0.00012171863,0.0000486451,0.00003087043,0.0000032385085,0.00021898173,0.0000579753,0.000023104481],"category_scores_gemma":[0.00008926731,0.000043841555,0.00006008125,0.00009128708,0.00035861152,0.0000016088242,0.00006561792,0.000041944106,0.0000011932223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006557422,0.00007042597,0.002654781,0.000008935131,0.000002745804,0.0000020063674,0.000038922477,0.000028487608,0.9890458,0.00067913946,0.000006703491,0.0073964745],"study_design_scores_gemma":[0.0001296197,0.0013426212,0.011047054,0.00002612051,9.461257e-7,7.648783e-7,0.000048133472,0.000016321868,0.9861131,0.0010154047,0.00019948898,0.0000604726],"about_ca_topic_score_codex":0.000011285753,"about_ca_topic_score_gemma":0.0000057908674,"teacher_disagreement_score":0.0083922725,"about_ca_system_score_codex":0.000001198431,"about_ca_system_score_gemma":0.000013741225,"threshold_uncertainty_score":0.17878067},"labels":[],"label_agreement":null},{"id":"W2069616965","doi":"10.1016/j.bmc.2006.05.019","title":"Short pseudopeptides containing turn scaffolds with high AT2 receptor affinity","year":2006,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Vetenskapsrådet","keywords":"Chemistry; Receptor; Turn (biochemistry); Amino acid; Stereochemistry; Affinities; Amino acid residue; Peptide; Angiotensin II; Combinatorial chemistry; Biochemistry; Peptide sequence","score_opus":0.006088149889649584,"score_gpt":0.20136613492476677,"score_spread":0.19527798503511717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069616965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99549776,0.0009016388,0.0008093339,0.00015311378,0.00017760975,0.00014612645,0.000025201221,0.00006477844,0.0022244307],"genre_scores_gemma":[0.9946818,0.00007397554,0.001396718,0.000161589,0.0018612058,0.00002058913,0.00043294646,0.0000681942,0.0013029823],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980493,0.000034049,0.0003768363,0.00063983194,0.0003982797,0.0005016982],"domain_scores_gemma":[0.9990399,0.0000177285,0.00013177328,0.00045357153,0.00015488069,0.00020216746],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003192565,0.00037382756,0.0003416835,0.000024577783,0.00016909161,0.000045706172,0.0003421741,0.00033625803,0.0008922279],"category_scores_gemma":[0.00005549937,0.00030864234,0.00010005467,0.00016384084,0.0001669144,0.000008193992,0.00010533593,0.0001784807,0.000020758325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019322745,0.000069448135,0.0020174154,0.00004732628,0.0000639555,0.000019632225,0.000019744724,0.000007910345,0.994386,0.000034863322,0.0023550764,0.00078537274],"study_design_scores_gemma":[0.0007480381,0.00032525888,0.001276557,0.0001000109,0.00005975721,0.0001199753,0.00034130068,0.0000063845478,0.9899845,0.000038162852,0.006576665,0.0004234032],"about_ca_topic_score_codex":0.00015517995,"about_ca_topic_score_gemma":0.000019665275,"teacher_disagreement_score":0.0044015413,"about_ca_system_score_codex":0.00006007113,"about_ca_system_score_gemma":0.00017741902,"threshold_uncertainty_score":0.9999366},"labels":[],"label_agreement":null},{"id":"W2069979742","doi":"10.1016/s0165-3806(00)00011-0","title":"Conversion and storage of somatostatin are established before response to secretagogue stimuli in P19 neurons","year":2000,"lang":"en","type":"article","venue":"Developmental Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"","keywords":"Biology; Secretagogue; P19 cell; Cell biology; Neuropeptide; Furin; Somatostatin; Proprotein Convertases; Secretion; Depolarization; NeuroD; Embryonic stem cell; Neuroscience; Cellular differentiation; Endocrinology; Biochemistry; Receptor","score_opus":0.026066422862587663,"score_gpt":0.31224675355272036,"score_spread":0.2861803306901327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069979742","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986499,0.00006722505,0.00007007483,0.0005811759,0.000024252486,0.0003333828,0.000033861263,0.000005298743,0.00023482702],"genre_scores_gemma":[0.9959382,0.000024767518,0.0020273526,0.00022079292,0.00001554261,0.000022116064,0.000069245616,0.000019584464,0.0016624093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841636,0.00035742766,0.00021390492,0.00035992765,0.0003154817,0.00033687273],"domain_scores_gemma":[0.99949473,0.00010902275,0.00002675091,0.00014556746,0.000074938245,0.00014896049],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013206216,0.000112933274,0.00014600763,0.0001899406,0.000099861674,0.00003071446,0.00017531934,0.00010217787,0.000485842],"category_scores_gemma":[0.00037687502,0.00011264979,0.000023952009,0.00029654073,0.00008524956,0.000008406983,0.00018706582,0.00015781172,0.000018470068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012502942,0.000052202347,0.0070382194,0.00003510212,0.000011124323,0.00003681176,0.0012725383,0.0000788754,0.98228484,0.000009441425,0.0021393346,0.0057912045],"study_design_scores_gemma":[0.0024822804,0.0014195242,0.15666516,0.00018741156,0.0000026873283,0.00003804103,0.006024222,0.00052154856,0.7998328,0.000099646175,0.032303978,0.00042268835],"about_ca_topic_score_codex":0.000076478886,"about_ca_topic_score_gemma":0.000085125765,"teacher_disagreement_score":0.18245204,"about_ca_system_score_codex":0.00004296623,"about_ca_system_score_gemma":0.00017466517,"threshold_uncertainty_score":0.53196293},"labels":[],"label_agreement":null},{"id":"W2069999016","doi":"10.1016/j.cellsig.2010.09.002","title":"Cytoplasmic tail of D1 dopaminergic receptor differentially regulates desensitization and phosphorylation by G protein-coupled receptor kinase 2 and 3","year":2010,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor kinase; Homologous desensitization; Beta adrenergic receptor kinase; Desensitization (medicine); Phosphorylation; Receptor; Biology; Dopaminergic; Cell biology; Interleukin-13 receptor; Dopamine receptor; G protein-coupled receptor; Internal medicine; Endocrinology; Dopamine; Signal transduction; Biochemistry; Medicine; Insulin-like growth factor 1 receptor","score_opus":0.003859805296594793,"score_gpt":0.18120849934611724,"score_spread":0.17734869404952244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069999016","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.975022,0.0010576345,0.023343613,0.000034245433,0.0001657142,0.000312897,0.00002152041,0.000017356733,0.000024979146],"genre_scores_gemma":[0.99348086,0.00019793698,0.005104469,0.000013554704,0.00015943508,0.0000145046415,0.00055973354,0.000039053448,0.0004304411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987928,0.000053822405,0.00035039216,0.00043626552,0.00015621271,0.00021046546],"domain_scores_gemma":[0.9993262,0.000021342461,0.00021793952,0.00018642505,0.00013960339,0.00010844165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003117281,0.00021371202,0.000218554,0.000053122167,0.000121702804,0.000052973257,0.00008836861,0.00025193658,0.00009904822],"category_scores_gemma":[0.00007866388,0.00020912854,0.00005666347,0.00007903589,0.000094597475,0.0000119352035,0.0000622374,0.00014401884,0.0000023317928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012512333,0.00003418825,0.0001195228,0.00004952688,0.000030531057,7.363737e-7,0.00006468953,0.000066106724,0.9981266,0.00014271279,0.000056402507,0.0011838201],"study_design_scores_gemma":[0.0006499707,0.00019298952,0.000018805735,0.000047518213,0.000025259244,0.0000027500744,0.000051858115,0.005465501,0.9923587,0.0001306916,0.00081531436,0.00024065873],"about_ca_topic_score_codex":0.000020496482,"about_ca_topic_score_gemma":0.000006997282,"teacher_disagreement_score":0.018458832,"about_ca_system_score_codex":0.000006595549,"about_ca_system_score_gemma":0.000030779516,"threshold_uncertainty_score":0.85280144},"labels":[],"label_agreement":null},{"id":"W2070340855","doi":"10.1089/108076802317373905","title":"Pharmacological and Molecular Biological (RT-PCR) Characterization of Functional TP Prostanoid Receptors in Immortalized Human Non-Pigmented Ciliary Epithelial Cells","year":2002,"lang":"en","type":"article","venue":"Journal of Ocular Pharmacology and Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Receptor; Prostanoid; Agonist; Phospholipase C; Receptor antagonist; Chemistry; Biology; Molecular biology; Antagonist; Endocrinology; Biochemistry","score_opus":0.022702669625970236,"score_gpt":0.2724968236606347,"score_spread":0.24979415403466448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070340855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949777,0.001489972,0.002631353,0.0001331577,0.0004961883,0.0002320135,0.000011505767,0.0000035068313,0.000024561174],"genre_scores_gemma":[0.9941355,0.004769168,0.00023085558,0.00060461817,0.00017221016,0.000007622654,0.000026406427,0.0000148898935,0.00003870709],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986254,0.00025365854,0.0005371614,0.00022589791,0.0001470592,0.00021085293],"domain_scores_gemma":[0.9993375,0.00002030765,0.0003583146,0.0000619687,0.0001312579,0.00009065526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044741287,0.00018991383,0.0003368444,0.00011190939,0.000075685326,0.000012022174,0.00011129372,0.00026531954,0.00040619922],"category_scores_gemma":[0.0000069398334,0.00015409695,0.00011351561,0.000099752535,0.00017346191,0.000014680461,0.00006058553,0.0002590463,8.17328e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045011748,0.00030439437,0.001959916,0.000016640712,0.00030470328,0.00003704089,0.00008551995,0.000031683907,0.99561363,0.000044235647,0.00003625061,0.0011158435],"study_design_scores_gemma":[0.003090624,0.0010608726,0.0016094645,0.000012228963,0.0001428705,0.00006176978,0.000039259896,0.00046767655,0.98984873,0.000115749725,0.0033863182,0.0001644384],"about_ca_topic_score_codex":8.6868505e-7,"about_ca_topic_score_gemma":2.2160282e-7,"teacher_disagreement_score":0.005764927,"about_ca_system_score_codex":0.000015163255,"about_ca_system_score_gemma":0.000024358917,"threshold_uncertainty_score":0.6283891},"labels":[],"label_agreement":null},{"id":"W2070354036","doi":"10.1021/ja404305k","title":"The Role of Ligands on the Equilibria Between Functional States of a G Protein-Coupled Receptor","year":2013,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"College of Family Physicians of Canada; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Chemistry; Transmembrane domain; Enthalpy; Population; G protein-coupled receptor; Stereochemistry; Crystallography; Micelle; Receptor; Biophysics; Biochemistry; Physical chemistry; Thermodynamics; Aqueous solution","score_opus":0.006744814601990088,"score_gpt":0.21180410064933652,"score_spread":0.20505928604734644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070354036","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99758583,0.00023338986,0.0001417918,0.0018189127,0.000049937647,0.00013359304,0.0000072143876,0.0000013840347,0.00002797188],"genre_scores_gemma":[0.99879926,0.00009817342,0.0004977964,0.00018834462,0.00032965266,0.000007816272,0.0000029337675,0.0000117752725,0.000064268104],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904275,0.000051025076,0.00035898737,0.00009395819,0.00029897442,0.00015428632],"domain_scores_gemma":[0.99861825,0.00013699525,0.00077020854,0.0002128704,0.00021301328,0.000048651375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042420713,0.000101765756,0.00021249602,0.00000492487,0.000084742205,0.000017191038,0.0004147578,0.000053704556,0.000058263282],"category_scores_gemma":[0.00013938105,0.000044651166,0.00046680588,0.00011030991,0.00034243683,0.0000043241344,0.00011436592,0.00021101798,0.0000012049841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007103874,0.000028282795,0.00052519963,0.000003575555,0.00018143981,1.0717246e-8,0.00006433538,0.00001273465,0.9953684,0.000045299385,0.0025065064,0.0011931296],"study_design_scores_gemma":[0.00016013203,0.00027054083,0.0003323952,0.000024809078,0.000022143122,0.0000014606422,0.0007221395,0.00014993035,0.9946482,0.0012244917,0.0023874955,0.000056266606],"about_ca_topic_score_codex":0.000023706089,"about_ca_topic_score_gemma":1.3565139e-7,"teacher_disagreement_score":0.0016305681,"about_ca_system_score_codex":0.000018547216,"about_ca_system_score_gemma":0.000071969596,"threshold_uncertainty_score":0.18208218},"labels":[],"label_agreement":null},{"id":"W2070458501","doi":"10.1016/s0163-7258(02)00300-5","title":"Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function","year":2002,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":263,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Palmitoylation; G protein-coupled receptor; Cell biology; G protein; Biology; G protein-coupled receptor kinase; Regulator of G protein signaling; Function (biology); Receptor; Signal transduction; Rhodopsin-like receptors; GTPase-activating protein; Biochemistry","score_opus":0.04084262781151204,"score_gpt":0.3226008424896731,"score_spread":0.28175821467816103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070458501","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0025819317,0.99472237,0.0006017806,0.000020193687,0.0007900715,0.0009943298,0.000033311808,0.00002324581,0.00023279514],"genre_scores_gemma":[0.004333114,0.9933416,0.00035623045,0.000095509065,0.0006530772,0.00024491304,0.00044865595,0.00008230061,0.00044457515],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99784195,0.0003493771,0.0008328611,0.0004906553,0.00016807838,0.00031706452],"domain_scores_gemma":[0.9988594,0.00005006288,0.0006167727,0.0002878095,0.00012419462,0.000061757586],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00030223845,0.00038794056,0.00076608476,0.00024382517,0.00008508781,0.000013419815,0.0002446253,0.0007519351,0.0008342592],"category_scores_gemma":[0.000007516489,0.00037548336,0.00035089217,0.0003197786,0.00006586001,0.000008436192,0.00006109251,0.00041144193,0.000044680095],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005713441,0.00015918697,0.0000080281025,0.0006608929,0.00052464724,6.763342e-7,0.000033583383,0.000062035964,0.6736839,0.000043114822,0.00007105047,0.32469574],"study_design_scores_gemma":[0.0004612348,0.00023057796,0.0000028262552,0.00040476842,0.0008723187,0.000007131717,0.000027757917,0.00038436052,0.024279421,0.00009965922,0.9728906,0.0003393364],"about_ca_topic_score_codex":0.000014900697,"about_ca_topic_score_gemma":0.0000074016966,"teacher_disagreement_score":0.97281957,"about_ca_system_score_codex":0.00007513255,"about_ca_system_score_gemma":0.0001435642,"threshold_uncertainty_score":0.9998697},"labels":[],"label_agreement":null},{"id":"W2070493428","doi":"10.1073/pnas.1312515110","title":"Pepducin targeting the C-X-C chemokine receptor type 4 acts as a biased agonist favoring activation of the inhibitory G protein","year":2013,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Allosteric regulation; Biology; Receptor; Cell biology; Signal transduction; Functional selectivity; Agonist; Chemokine receptor; G protein; Arrestin; Biochemistry; Chemokine","score_opus":0.02358225611089497,"score_gpt":0.2642037970567323,"score_spread":0.24062154094583732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070493428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959771,0.00005968587,0.0000021636688,0.002506048,0.000039503564,0.00034305768,0.0000022645163,0.0000030004508,0.0010671825],"genre_scores_gemma":[0.9987004,0.000011395637,0.0006818363,0.00015681374,0.00017286387,0.00001899076,4.890299e-7,0.00000536673,0.00025184022],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880993,0.000014253153,0.00025795022,0.00018812685,0.00060692756,0.00012281898],"domain_scores_gemma":[0.9990531,0.000029139323,0.0004942846,0.00001740468,0.00038649686,0.000019544783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010032082,0.000085627384,0.00009440225,0.000035686815,0.0002471178,0.000025549656,0.0006210708,0.0000891433,0.000035858724],"category_scores_gemma":[0.001126987,0.000043719065,0.00007421176,0.0003842974,0.0003526891,0.00003490195,0.00017269314,0.00012988632,0.0000010654081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011785628,0.000016743998,0.0002702307,0.00002694602,0.00000962683,2.3121942e-10,0.00009656488,0.0000580691,0.99687773,0.0019249684,0.0005366597,0.00017066054],"study_design_scores_gemma":[0.00008949912,0.00006565414,0.0012596442,0.00009881327,0.000004048803,6.817358e-7,0.00032044688,0.00014415223,0.9947916,0.0025546718,0.0006153495,0.000055389974],"about_ca_topic_score_codex":0.000020670837,"about_ca_topic_score_gemma":4.2920373e-8,"teacher_disagreement_score":0.00272331,"about_ca_system_score_codex":0.00001566958,"about_ca_system_score_gemma":0.00006783766,"threshold_uncertainty_score":0.19006553},"labels":[],"label_agreement":null},{"id":"W2070837896","doi":"10.1021/cb5006323","title":"Identification and Structure–Function Analysis of Subfamily Selective G Protein-Coupled Receptor Kinase Inhibitors","year":2014,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Structural Genomics Consortium; National Heart, Lung, and Blood Institute; Wellcome Trust; Wellcome; American Heart Association","keywords":"G protein-coupled receptor kinase; Beta adrenergic receptor kinase; Kinase; Biochemistry; Transferase; Drug discovery; Biology; Subfamily; G protein-coupled receptor; Chemistry; Receptor; Enzyme; Gene","score_opus":0.004140793464096301,"score_gpt":0.21577927497297653,"score_spread":0.21163848150888023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070837896","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923633,0.00016543748,0.0071415063,0.000030893243,0.00009345591,0.00015006925,0.000021212407,0.000009846011,0.000024333252],"genre_scores_gemma":[0.99864393,0.000021900398,0.0005180704,0.00006044543,0.00014143968,0.000018343437,0.00055340864,0.0000106794505,0.000031785075],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990224,0.00007867822,0.00027707012,0.00039812928,0.00006327637,0.0001604281],"domain_scores_gemma":[0.9994168,0.000023714832,0.00017050513,0.00019858917,0.00013463946,0.000055710578],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019398813,0.0001318956,0.00024431487,0.00009180177,0.00003941739,0.000009212614,0.00009490479,0.00029150627,0.00004042987],"category_scores_gemma":[0.0002169025,0.00011623741,0.00008505552,0.00026094486,0.00010112816,0.0000037967575,0.000057638117,0.000083750754,0.0000015112076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001043158,0.000020201853,0.0010195547,0.00000896135,0.0002475485,2.616223e-8,0.000018380399,0.000008264357,0.9950976,0.00050787575,0.00004124546,0.0029260702],"study_design_scores_gemma":[0.00025489245,0.00021651402,0.0004605624,0.000003656507,0.00015828246,4.54135e-7,0.000018300289,0.00035133478,0.9969661,0.0008497096,0.00059122004,0.00012896079],"about_ca_topic_score_codex":0.000024129533,"about_ca_topic_score_gemma":0.0000062792346,"teacher_disagreement_score":0.006623436,"about_ca_system_score_codex":0.000011629895,"about_ca_system_score_gemma":0.000015951078,"threshold_uncertainty_score":0.4740024},"labels":[],"label_agreement":null},{"id":"W2071109113","doi":"10.1074/jbc.m413653200","title":"Determining the Environment of the Ligand Binding Pocket of the Human Angiotensin II Type I (hAT1) Receptor Using the Methionine Proximity Assay","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Methionine; Chemistry; Receptor; Ligand (biochemistry); Biochemistry; Angiotensin II; Amino acid","score_opus":0.03158797483603505,"score_gpt":0.2622211259495332,"score_spread":0.23063315111349814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071109113","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985163,0.0005676947,0.00010478091,0.0005248325,0.00012028534,0.00010127606,0.000006743592,0.0000013302001,0.000056760637],"genre_scores_gemma":[0.9983931,0.00008476738,0.00088312593,0.0001357076,0.00036166486,8.897714e-7,0.0000029430332,0.0000089199875,0.00012885024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988108,0.00017766231,0.00046548236,0.00014580079,0.00023222297,0.00016800381],"domain_scores_gemma":[0.9987563,0.000057335084,0.0007396552,0.00031581495,0.00009332022,0.00003757819],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010830418,0.00014356102,0.00021827246,0.0000075986186,0.00031094102,0.000013434853,0.00057819445,0.0002145756,0.000086636916],"category_scores_gemma":[0.00026488738,0.000053905413,0.00030081003,0.00008574775,0.0002542018,0.000005272119,0.0003294722,0.00033233105,2.3751372e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002412384,0.00005650113,0.0025321015,0.0000054617676,0.00005897039,1.893673e-7,0.00006177712,0.00017028785,0.99640095,0.0000039386478,0.00013731935,0.0005483636],"study_design_scores_gemma":[0.0002188434,0.00014003628,0.0010066447,0.000052388583,0.000045443878,0.000024559415,0.0001369852,0.00004576198,0.994876,0.000036041125,0.0033397612,0.000077528086],"about_ca_topic_score_codex":0.0000015991276,"about_ca_topic_score_gemma":3.609067e-7,"teacher_disagreement_score":0.0032024416,"about_ca_system_score_codex":0.000030681633,"about_ca_system_score_gemma":0.000057815567,"threshold_uncertainty_score":0.23915382},"labels":[],"label_agreement":null},{"id":"W2071388041","doi":"10.1074/jbc.m114.559294","title":"Coupling of G Proteins to Reconstituted Monomers and Tetramers of the M2 Muscarinic Receptor","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"Oxotremorine; Chemistry; Allosteric regulation; Receptor; Muscarinic acetylcholine receptor; Biophysics; Agonist; Ligand (biochemistry); Vesicle; Monomer; G protein-coupled receptor; Stereochemistry; Membrane; Biochemistry; Biology","score_opus":0.013538474192310558,"score_gpt":0.2263353214977117,"score_spread":0.21279684730540116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071388041","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982048,0.00024453556,0.0010608166,0.00008375805,0.000102515005,0.00007955656,0.0000070272044,0.0000015059854,0.00021543384],"genre_scores_gemma":[0.99754506,0.0001243433,0.002112686,0.000039784958,0.00013606246,0.0000018995926,0.0000026612042,0.0000052749065,0.000032242566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922585,0.000020196461,0.00039966562,0.00013879871,0.00009719276,0.00011831449],"domain_scores_gemma":[0.9992308,0.000030290685,0.0003789476,0.00014578385,0.0001240555,0.000090113936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004082529,0.000099993435,0.00024242455,0.000014682958,0.000031130923,0.0000057756965,0.00022363584,0.00017187592,0.000058484908],"category_scores_gemma":[0.00045629917,0.000060994807,0.00014446884,0.00007077997,0.00013920736,0.0000024549788,0.00008635935,0.00013983416,2.5733533e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008700355,0.000029594232,0.0019476742,0.00002831694,0.000037796926,1.7951321e-7,0.000014220244,0.00020061646,0.9963512,0.000010855773,0.000049505954,0.0012430657],"study_design_scores_gemma":[0.00025839428,0.00034009252,0.0005991903,0.00006858771,0.000012087753,0.000012769674,0.00011446334,0.000038312694,0.99623865,0.000041151972,0.0021974903,0.000078838246],"about_ca_topic_score_codex":0.0000025560526,"about_ca_topic_score_gemma":2.789128e-7,"teacher_disagreement_score":0.0021479845,"about_ca_system_score_codex":0.000008704632,"about_ca_system_score_gemma":0.00004770183,"threshold_uncertainty_score":0.2487296},"labels":[],"label_agreement":null},{"id":"W2071728564","doi":"10.1021/bi0258602","title":"Residues 293 and 294 Are Ligand Contact Points of the Human Angiotensin Type 1 Receptor","year":2002,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Chemistry; Receptor; Transmembrane domain; Mutant; Residue (chemistry); Ligand (biochemistry); Biochemistry; Transmembrane protein; Stereochemistry; Angiotensin II","score_opus":0.014290789604771746,"score_gpt":0.2246798466281463,"score_spread":0.21038905702337454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071728564","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99649274,0.0024301617,0.000006117097,0.00021397755,0.00010626093,0.0000744297,0.000020797113,0.000007780585,0.00064774195],"genre_scores_gemma":[0.9972445,0.00017380831,0.00022710353,0.00012351782,0.00021097623,0.0000021543995,0.000022403003,0.000017538538,0.0019779974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992775,0.00002447122,0.00016928042,0.0002638721,0.000110598136,0.00015432046],"domain_scores_gemma":[0.9993743,0.000007042723,0.0001292126,0.00034010605,0.000089353496,0.000060028728],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000089243855,0.00013543195,0.00014238383,0.000010921936,0.000097238626,0.00001817947,0.00015964438,0.00018941586,0.00014717263],"category_scores_gemma":[0.0000906969,0.00010509538,0.00007706641,0.00006402484,0.00007492499,0.0000021494338,0.000102572936,0.000080026024,0.000003898986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013250774,0.000025332582,0.0029223387,0.000025139758,0.000028230654,9.959579e-7,0.000026719534,2.9586107e-7,0.9857428,0.000014035211,0.011065914,0.00013493231],"study_design_scores_gemma":[0.0002493502,0.000069564034,0.0013943438,0.00006447449,0.000012629491,0.000012022309,0.00007364186,0.000005827703,0.9939226,0.000030346648,0.0040308083,0.0001343929],"about_ca_topic_score_codex":0.000009778237,"about_ca_topic_score_gemma":0.000002963472,"teacher_disagreement_score":0.008179784,"about_ca_system_score_codex":0.000008029741,"about_ca_system_score_gemma":0.000014051042,"threshold_uncertainty_score":0.42856652},"labels":[],"label_agreement":null},{"id":"W2071793091","doi":"10.1038/nm.2263","title":"Uncoupling the dopamine D1-D2 receptor complex exerts antidepressant-like effects","year":2010,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Carleton University; Centre for Addiction and Mental Health","funders":"Centre for Addiction and Mental Health","keywords":"Dopamine; Learned helplessness; Dopamine receptor D2; Antidepressant; Behavioural despair test; Receptor; Neurotransmitter; Dopamine receptor; Neurotransmitter receptor; Dopamine receptor D1; Neuroscience; Psychology; Internal medicine; Endocrinology; Pharmacology; Biology; Medicine; Developmental psychology; Hippocampus","score_opus":0.006160488464611257,"score_gpt":0.25769199944182225,"score_spread":0.251531510977211,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071793091","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849236,0.004276019,0.0020719087,0.001858558,0.0049037524,0.0004159358,0.000007524047,0.000043097163,0.0014996245],"genre_scores_gemma":[0.99214023,0.00023655345,0.0012741372,0.002168794,0.0031335396,0.00001973991,0.00021315538,0.000039118066,0.00077471795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986469,0.000050805593,0.00023296545,0.0004200404,0.0003285331,0.00032072046],"domain_scores_gemma":[0.99897337,0.000095621326,0.00011183404,0.00055827555,0.00013714006,0.00012377137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054428825,0.00024506386,0.00026590962,0.000046828205,0.00019566751,0.00001958172,0.0003917565,0.00046902578,0.00048541956],"category_scores_gemma":[0.00041425257,0.00014312561,0.000085224805,0.00014525541,0.00016662451,0.0000037845434,0.00010718833,0.0008608448,0.000013346211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056677385,0.00002143811,0.00029266905,0.00002820458,0.000037647664,0.000006089604,0.000039414605,0.0000063752063,0.9722019,0.00023391093,0.023010684,0.0040650247],"study_design_scores_gemma":[0.0008917522,0.0002916994,0.0007852869,0.000062968014,0.000039507384,0.000033487784,0.000056732464,0.00014706877,0.6843159,0.00010582751,0.313074,0.00019574456],"about_ca_topic_score_codex":0.000024175071,"about_ca_topic_score_gemma":0.000043424483,"teacher_disagreement_score":0.29006332,"about_ca_system_score_codex":0.0000063763464,"about_ca_system_score_gemma":0.000030633666,"threshold_uncertainty_score":0.5836493},"labels":[],"label_agreement":null},{"id":"W2072338182","doi":"10.1038/sj.npp.1300502","title":"Decreased Amphetamine-Induced Locomotion and Improved Latent Inhibition in Mice Mutant for the M5 Muscarinic Receptor Gene Found in the Human 15q Schizophrenia Region","year":2004,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Nucleus accumbens; Amphetamine; Dopamine; Striatum; Dopamine receptor D2; Dopamine receptor D1; Dopamine receptor; Muscarinic acetylcholine receptor M1; Ventral tegmental area; Endocrinology; Internal medicine; Dopamine receptor D3; Biology; Muscarinic acetylcholine receptor; Receptor; Neuroscience; Medicine; Dopaminergic","score_opus":0.02173122047487711,"score_gpt":0.2840789729223993,"score_spread":0.2623477524475222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072338182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956524,0.00024084037,0.0014217555,0.0009650239,0.00054068153,0.0011504499,0.0000049813793,0.000010817846,0.000013064483],"genre_scores_gemma":[0.99753916,0.00027528903,0.00021974627,0.0012700255,0.0003322795,0.00026454186,0.000054977958,0.000030111963,0.000013886873],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985771,0.00022944892,0.0003356794,0.00047128214,0.00008591942,0.0003005235],"domain_scores_gemma":[0.9994832,0.000059159727,0.000134534,0.0002092389,0.00006088313,0.00005293553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039863365,0.00019810641,0.00016432349,0.000079826976,0.00016175951,0.000034519217,0.0001675986,0.0001711322,0.0000116625],"category_scores_gemma":[0.00004394013,0.00014329303,0.00007477989,0.00018610222,0.000062784246,0.000009125445,0.00004767232,0.00023074188,0.0000019194556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005623029,0.00015027638,0.0000531039,0.000014000997,0.000017011958,0.000012979698,0.00011398309,0.0001956965,0.99694216,0.000098555276,0.00004913207,0.0017907675],"study_design_scores_gemma":[0.013862762,0.0015101256,0.010119087,0.000032716707,0.000067081906,0.00014691215,0.00012652071,0.00063710706,0.9713715,0.0007839023,0.0010081019,0.00033419687],"about_ca_topic_score_codex":0.00009465748,"about_ca_topic_score_gemma":0.0001871374,"teacher_disagreement_score":0.025570704,"about_ca_system_score_codex":0.000035524798,"about_ca_system_score_gemma":0.000048562215,"threshold_uncertainty_score":0.58433205},"labels":[],"label_agreement":null},{"id":"W2072355351","doi":"10.1038/sj.bjp.0704067","title":"Drug‐disease interactions: reduced β‐adrenergic and potassium channel antagonist activities of sotalol in the presence of acute and chronic inflammatory conditions in the rat","year":2001,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"American Association of Pharmaceutical Scientists","keywords":"Sotalol; Pharmacology; Potassium channel blocker; Medicine; Potassium channel; Internal medicine; Endocrinology; Arthritis; Antagonist; Receptor","score_opus":0.008010711529554647,"score_gpt":0.27732642294355775,"score_spread":0.2693157114140031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072355351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99506533,0.0040142536,0.00003507757,0.00048146883,0.00020862221,0.00014067703,0.000028553706,6.904283e-7,0.000025340438],"genre_scores_gemma":[0.99111086,0.008528398,0.0000123601885,0.0001260552,0.00016363543,0.00001691814,0.0000078232615,0.000005502282,0.000028416945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991188,0.0002830232,0.000275479,0.00010021079,0.00008905862,0.00013341795],"domain_scores_gemma":[0.99957204,0.00006574995,0.00022690544,0.000049091595,0.000053543892,0.00003268201],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038137677,0.00007352481,0.00015060825,0.00007130252,0.00006162769,0.000019419398,0.0001598647,0.000038387334,0.000036565765],"category_scores_gemma":[0.000020337115,0.000060767376,0.00005083748,0.000071424016,0.00018860484,0.000022527951,0.00003997769,0.00019595325,5.0263314e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019491966,0.000106241125,0.00019441081,0.000027912263,0.000058493482,0.00019129972,0.00031533535,0.00015246769,0.99724793,0.000037958886,0.0009060195,0.00056700315],"study_design_scores_gemma":[0.0027216107,0.00042974332,0.0074344375,0.00021124248,0.00018029434,0.0045164702,0.0025703884,0.00040143068,0.97970605,0.00044739296,0.0012201602,0.00016076353],"about_ca_topic_score_codex":0.000028435965,"about_ca_topic_score_gemma":0.00008141891,"teacher_disagreement_score":0.017541872,"about_ca_system_score_codex":0.000012125363,"about_ca_system_score_gemma":0.00012311946,"threshold_uncertainty_score":0.24780217},"labels":[],"label_agreement":null},{"id":"W2072363892","doi":"10.1016/j.molimm.2009.08.013","title":"Recombinant C3adesArg/acylation stimulating protein (ASP) is highly bioactive: A critical evaluation of C5L2 binding and 3T3-L1 adipocyte activation","year":2009,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut Universitaire de Cardiologie et de Pneumologie de Québec; McGill University; Université Laval","funders":"Canada Research Chairs","keywords":"Transfection; HEK 293 cells; Recombinant DNA; Receptor; Molecular biology; iC3b; Chinese hamster ovary cell; Biochemistry; Chemistry; Biology; Antibody; Complement system; Immunology; Gene","score_opus":0.017380400525745153,"score_gpt":0.29668968920952216,"score_spread":0.279309288683777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072363892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9755495,0.000970553,0.022294821,0.0004132034,0.00010893937,0.00046270574,0.0000043136642,0.000014751859,0.00018122232],"genre_scores_gemma":[0.99578744,0.00003189961,0.003872888,0.0001089355,0.000035348497,0.00003084077,0.000082015526,0.000021080717,0.000029564737],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839854,0.00030460258,0.00035155177,0.00042425143,0.00025107677,0.00026997156],"domain_scores_gemma":[0.9991784,0.000023506016,0.0001779216,0.00026672814,0.00031172647,0.00004173171],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062011875,0.00019096321,0.00022302677,0.00013697,0.00012272871,0.00002764635,0.00010871955,0.00029439674,0.00005465325],"category_scores_gemma":[0.0004525053,0.00019860247,0.00008029864,0.000145561,0.00008179356,0.000019523144,0.00005663364,0.00014484447,0.000002964389],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013369562,0.000067396766,0.00004138943,0.000012283625,0.00006925117,0.0000013744212,0.00011069115,0.000121413825,0.9735509,0.0013833233,0.000007748326,0.0245005],"study_design_scores_gemma":[0.0009819817,0.0009445624,0.0010583055,0.00007199254,0.000065467,0.0000118976595,0.00008071543,0.0035143036,0.99034184,0.0025773924,0.00014485237,0.00020666585],"about_ca_topic_score_codex":0.000021913831,"about_ca_topic_score_gemma":7.252521e-7,"teacher_disagreement_score":0.024293834,"about_ca_system_score_codex":0.000047966994,"about_ca_system_score_gemma":0.000086343796,"threshold_uncertainty_score":0.8098774},"labels":[],"label_agreement":null},{"id":"W2072375322","doi":"10.1074/jbc.m110.165134","title":"B-Raf Associates with and Activates the NHE1 Isoform of the Na+/H+ Exchanger","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Tufts University School of Medicine; Fondation pour la Recherche Médicale; University of Alberta; Heart and Stroke Foundation of Canada","keywords":"Kinase; Intracellular pH; MAPK/ERK pathway; Intracellular; Protein kinase A; Cytosol; Molecular biology; Chemistry; Cell growth; HEK 293 cells; Phosphorylation; Biology; Biochemistry; Enzyme; Receptor","score_opus":0.02424978022931444,"score_gpt":0.216372127398287,"score_spread":0.19212234716897258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072375322","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982779,0.00081878627,0.000080365775,0.00010021408,0.00004090874,0.000039999748,0.0000041082826,0.0000014943572,0.0006362007],"genre_scores_gemma":[0.99908346,0.0002595653,0.0002890272,0.00009211391,0.00013763223,0.0000017092955,0.0000014260651,0.0000055636083,0.0001294908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999442,0.00003233078,0.00019730222,0.00009875582,0.00010450717,0.00012512719],"domain_scores_gemma":[0.99937123,0.0000270848,0.0003327023,0.00012271309,0.00010374655,0.00004253204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028579406,0.000099728764,0.00015161745,0.0000048947522,0.000063809384,0.000008820786,0.0002429262,0.00015461206,0.000114006056],"category_scores_gemma":[0.00010998567,0.00003889106,0.000105255865,0.000043353728,0.0001580161,0.0000033399292,0.00009024837,0.00016054332,1.6936622e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011726886,0.000036067846,0.008883193,0.000009173349,0.00007118787,0.0000010039491,0.000074507916,6.64054e-7,0.990224,0.000008869812,0.000079595324,0.0004944572],"study_design_scores_gemma":[0.00021925427,0.00026532242,0.0073698354,0.00002647851,0.000018985791,0.00006913026,0.00031924044,0.0000015741373,0.9907053,0.00022036204,0.00071847823,0.00006601628],"about_ca_topic_score_codex":0.0000031198408,"about_ca_topic_score_gemma":4.8513647e-7,"teacher_disagreement_score":0.0015133579,"about_ca_system_score_codex":0.000006585071,"about_ca_system_score_gemma":0.00002812322,"threshold_uncertainty_score":0.15859313},"labels":[],"label_agreement":null},{"id":"W2072497459","doi":"10.1124/mol.61.4.707","title":"Deactivation of Vasodilator Responses by GRK2 Overexpression:<i>A</i> Mechanism or <i>the</i> Mechanism for Hypertension?","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Mechanism (biology); Vasodilation; Medicine; Disease; Ideal (ethics); Statement (logic); Internal medicine; Cardiology; Intensive care medicine; Philosophy; Epistemology","score_opus":0.020732852954499933,"score_gpt":0.265976725882313,"score_spread":0.24524387292781308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072497459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8998301,0.0007087247,0.09647281,0.00105936,0.00068658596,0.0009897614,0.00011166907,0.000031780113,0.000109219865],"genre_scores_gemma":[0.99029577,0.0003706433,0.0026501492,0.0049670655,0.00019875636,0.00024855728,0.00006939308,0.00006239721,0.0011372835],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833935,0.00021796035,0.0003799448,0.00047296012,0.00022086797,0.00036890054],"domain_scores_gemma":[0.99899244,0.000109468536,0.00023730227,0.00032179256,0.00023595794,0.000103063896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029985415,0.00025440587,0.00028772475,0.000055814846,0.00018759423,0.000016189066,0.0003293409,0.00026750675,0.0005779539],"category_scores_gemma":[0.00014545178,0.00017097044,0.00019202051,0.00011954198,0.00006543872,0.000008678162,0.00011911652,0.00012567233,0.0000068384857],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005165815,0.0001429766,0.0000021578633,0.000019764166,0.0001200497,0.000007467935,0.000033570683,0.000015651169,0.9674547,0.0018403563,0.02935084,0.0004959306],"study_design_scores_gemma":[0.0015740308,0.00064329704,9.4899025e-7,0.000014246051,0.000078778045,0.00004324421,0.00004846907,0.00086924335,0.9660775,0.0015555666,0.028860768,0.0002339221],"about_ca_topic_score_codex":0.000007905514,"about_ca_topic_score_gemma":7.479813e-7,"teacher_disagreement_score":0.09382266,"about_ca_system_score_codex":0.000017328,"about_ca_system_score_gemma":0.000043894142,"threshold_uncertainty_score":0.6971972},"labels":[],"label_agreement":null},{"id":"W2072541455","doi":"10.1139/o00-019","title":"Cytosensor techniques for examining signal transduction of neurohormones","year":2000,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Neurohormones; Transduction (biophysics); Signal transduction; Biology; Neuropeptide; G protein-coupled receptor; Hormone; Computational biology; Receptor; Biochemistry","score_opus":0.011010653556432555,"score_gpt":0.22721329588765027,"score_spread":0.21620264233121772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072541455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951212,0.0010805334,0.002127882,0.00002014954,0.000034802277,0.00012992318,0.00003919389,0.000014026019,0.00143232],"genre_scores_gemma":[0.99557453,0.0006149008,0.002470746,0.00004734883,0.00023616971,0.000028475322,0.00014777904,0.000013090453,0.0008669761],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928266,0.000023917215,0.00018891327,0.000310441,0.000029637222,0.00016445032],"domain_scores_gemma":[0.9997146,0.000014833278,0.000059160717,0.00012797277,0.00003796214,0.00004547764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011154982,0.00012873925,0.0001470801,0.000015532401,0.000059834514,0.0000057988855,0.00008254748,0.00024323288,0.00021082215],"category_scores_gemma":[0.000008129532,0.000120816716,0.00006179329,0.000030928462,0.00009214122,0.0000019823249,0.000013582626,0.000046696787,5.368252e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015515936,0.00002969296,0.000063845124,0.00004848399,0.0000122501215,2.2973077e-7,0.0000141912815,0.0000027080414,0.9627271,0.000013977366,0.000069636015,0.03686271],"study_design_scores_gemma":[0.0002545131,0.0005710069,0.000014721549,0.0000071093377,0.000015799167,0.000010491113,0.00004974641,0.000024772571,0.98019594,0.00008827726,0.018632172,0.00013545984],"about_ca_topic_score_codex":0.0000038065332,"about_ca_topic_score_gemma":2.0568636e-7,"teacher_disagreement_score":0.03672725,"about_ca_system_score_codex":0.000002391937,"about_ca_system_score_gemma":0.00001961156,"threshold_uncertainty_score":0.4926763},"labels":[],"label_agreement":null},{"id":"W2072694184","doi":"10.1002/wmts.52","title":"Desensitization and internalization mechanisms of the 5‐HT4 receptors","year":2012,"lang":"en","type":"article","venue":"Wiley Interdisciplinary Reviews Membrane Transport and Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Internalization; Desensitization (medicine); 5-HT4 receptor; Receptor; G protein-coupled receptor; Serotonin; Agonist; 5-HT receptor; Neuroscience; Pharmacology; Antidepressant; Biology; Medicine; Internal medicine; Hippocampus","score_opus":0.014584893488702346,"score_gpt":0.25175011218002935,"score_spread":0.237165218691327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072694184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.81096756,0.011568002,0.17624822,0.000070742535,0.00047620642,0.00044903884,0.0000068685927,0.0000104738165,0.00020291134],"genre_scores_gemma":[0.99212027,0.0062104403,0.0011801968,0.00008684378,0.00015713916,0.000015748417,0.000064697866,0.000024639723,0.00014001151],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886346,0.00010378964,0.00046220174,0.00024144341,0.00012611644,0.00020296602],"domain_scores_gemma":[0.999474,0.000011604178,0.00020013722,0.00017146196,0.000048520335,0.00009426118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062787096,0.00019478785,0.0002945503,0.00004064067,0.00015035286,0.000011375862,0.00012196246,0.00011520042,0.00007774155],"category_scores_gemma":[0.000013476076,0.0001362196,0.00013921277,0.000101130536,0.000074769894,0.00002331045,0.0001004246,0.00009641021,0.0000012463811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005940331,0.000036189966,0.0035131655,0.00024314455,0.000038266426,3.9552984e-7,0.0009184281,0.0000695376,0.9901471,0.00086264586,0.000036148605,0.0040755384],"study_design_scores_gemma":[0.00042938822,0.00022867674,0.00079070235,0.001237454,0.00017202114,0.000058773654,0.00040103664,0.0004920901,0.98943365,0.0010262441,0.0053507998,0.0003791942],"about_ca_topic_score_codex":0.000003896552,"about_ca_topic_score_gemma":0.000009033616,"teacher_disagreement_score":0.18115275,"about_ca_system_score_codex":0.000006809915,"about_ca_system_score_gemma":0.000012071329,"threshold_uncertainty_score":0.55548745},"labels":[],"label_agreement":null},{"id":"W2072735940","doi":"10.1038/nchembio.97","title":"Insights into signaling from the β2-adrenergic receptor structure","year":2008,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Vedecká Grantová Agentúra MŠVVaŠ SR a SAV","keywords":"Rhodopsin; G protein-coupled receptor; Receptor; Signal transduction; Adrenergic receptor; Biology; Protein structure; Cell biology; Biochemistry","score_opus":0.006067680208475991,"score_gpt":0.22572962355005527,"score_spread":0.2196619433415793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072735940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887344,0.009423014,0.00052426883,0.0002929233,0.00071245414,0.00011129035,0.000038831757,0.00002667428,0.0001361387],"genre_scores_gemma":[0.99182886,0.0003050595,0.0028490582,0.002012524,0.001607007,0.000010622987,0.0013001594,0.000027651211,0.00005905246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866116,0.000101093276,0.00024585004,0.0005838546,0.000120268014,0.00028776427],"domain_scores_gemma":[0.9992182,0.00008125425,0.00009810799,0.00039813874,0.000100143334,0.00010411185],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00005461883,0.0002596716,0.00024318066,0.000022401302,0.00019436552,0.000013101787,0.00051372487,0.0013141981,0.00034619556],"category_scores_gemma":[0.00019577907,0.00016468992,0.00015197674,0.0001260737,0.00021018885,0.000003530064,0.00018003541,0.000687334,0.00001552198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068357585,0.000016511887,0.00035281104,0.0000022579645,0.00006178462,0.0000023249763,0.00009997952,0.0000080098025,0.9950035,0.000619959,0.0031506065,0.000613905],"study_design_scores_gemma":[0.00030581214,0.00006835274,0.000041935855,0.000007558946,0.000011812558,0.000009747585,0.000029540673,0.000012974482,0.9099747,0.0032519903,0.08606582,0.00021975326],"about_ca_topic_score_codex":0.000036168454,"about_ca_topic_score_gemma":0.000010124836,"teacher_disagreement_score":0.08502879,"about_ca_system_score_codex":0.000020735957,"about_ca_system_score_gemma":0.00006398903,"threshold_uncertainty_score":0.9999823},"labels":[],"label_agreement":null},{"id":"W2072736827","doi":"10.1016/s0006-2952(01)00742-0","title":"Sequestration and phosphorylation of the prostaglandin E2 EP4 receptor: dependence on the C-terminal tail33Abbreviations: PGE2, prostaglandin E2, GRK, G-protein coupled receptor kinase; PKA, protein kinase A; PKC, protein kinase C; PCR, polymerase chain reaction; DMEM, Dulbecco’s modified Eagle’s medium; PAS, protein A Sepharose; ECL, electrochemiluminescence; BCA, 2-bicinchoninic acid; IR, immunoreactivity; HBSS, Hanks’ buffered salt solution; TBS, Tris-buffered saline; cAMP, cyclic AMP; PMA, phorbol 12-myristate 13 acetate; and β2-AR, β2-adrenergic receptor.","year":2001,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"TransCanada (Canada)","funders":"","keywords":"Prostaglandin E2 receptor; Forskolin; Protein kinase C; Protein kinase A; Homologous desensitization; Phosphorylation; Adenylyl cyclase; Cell biology; Receptor; Chemistry; Biology; Prostaglandin E2; Agonist; Molecular biology; Signal transduction; Biochemistry; Endocrinology","score_opus":0.017407824000611475,"score_gpt":0.25045457643078783,"score_spread":0.23304675243017636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072736827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9831024,0.004303997,0.0007694333,0.0024263796,0.00036873607,0.008546681,0.00033494254,0.00011997652,0.000027478885],"genre_scores_gemma":[0.98953897,0.0010340327,0.0007045047,0.00026164038,0.00061308296,0.0043165907,0.0018129759,0.0001547654,0.0015634253],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99281293,0.0013279758,0.0016642394,0.0019257321,0.00091879617,0.0013503009],"domain_scores_gemma":[0.9962376,0.00015491967,0.001594687,0.001008291,0.0005084433,0.0004960646],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001635247,0.0012340673,0.0010754364,0.00025957305,0.00091818237,0.00018615686,0.00077720213,0.0010772119,0.0003801053],"category_scores_gemma":[0.0007184962,0.00097452244,0.00035032802,0.00074464775,0.0008221986,0.00014081209,0.0003624966,0.001306197,0.000019788198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.006732993,0.00085495337,0.00019079921,0.00025690979,0.0002565191,0.000014898402,0.00026189964,0.000010239411,0.98879766,0.0002095601,0.0016017517,0.00081182807],"study_design_scores_gemma":[0.005423738,0.0013062165,0.00022825004,0.00042986614,0.00019876008,0.000058829643,0.000119303426,0.00085295015,0.98793167,0.00024590493,0.0021258432,0.0010786563],"about_ca_topic_score_codex":0.0007869876,"about_ca_topic_score_gemma":0.00014170942,"teacher_disagreement_score":0.0064366073,"about_ca_system_score_codex":0.00045034915,"about_ca_system_score_gemma":0.0006959856,"threshold_uncertainty_score":0.9992705},"labels":[],"label_agreement":null},{"id":"W2072748745","doi":"10.1074/jbc.m002092200","title":"The Forgotten Serine","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"National Institute of Mental Health","keywords":"Chemistry; Stereochemistry; Partial agonist; Agonist; Adenylyl cyclase; Alprenolol; Serine; Cysteine; Affinities; Pindolol; SCH-23390; Receptor; Biochemistry; Enzyme","score_opus":0.010870191830303886,"score_gpt":0.23236437420596429,"score_spread":0.2214941823756604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072748745","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954404,0.0012636153,0.0001440436,0.0002500298,0.00006720491,0.000024031939,0.0000021815165,0.0000031572863,0.0028052847],"genre_scores_gemma":[0.99481094,0.0017454636,0.00039667558,0.00014761725,0.00072018866,0.0000015142733,0.0000062757017,0.000006363122,0.0021649634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993544,0.000023936758,0.0002620794,0.00010192746,0.00009616099,0.00016148784],"domain_scores_gemma":[0.99958354,0.00002023851,0.000116420735,0.00013053048,0.00007056502,0.00007871665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002965978,0.00008985509,0.000115176095,0.0000033146102,0.00009299395,0.000023934337,0.00027125256,0.00013669912,0.0008671578],"category_scores_gemma":[0.00008156583,0.00004672123,0.00015202005,0.00003443585,0.0000632569,0.0000019191857,0.000031510524,0.00013682242,0.0000061267974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014048336,0.00002063338,0.0002233624,0.0000025208617,0.000028768562,0.000006130998,0.0000028324287,0.000022212109,0.9839726,0.000006847354,0.0012657881,0.014307799],"study_design_scores_gemma":[0.00020866531,0.00019692289,0.00020442298,0.000005924089,0.0000047520516,0.00016144273,0.000032771524,0.0000065165195,0.7690844,0.00025809885,0.22976714,0.00006894446],"about_ca_topic_score_codex":4.3074655e-7,"about_ca_topic_score_gemma":1.2552908e-7,"teacher_disagreement_score":0.22850135,"about_ca_system_score_codex":0.000007087373,"about_ca_system_score_gemma":0.000026707068,"threshold_uncertainty_score":0.949477},"labels":[],"label_agreement":null},{"id":"W2072864645","doi":"10.1039/c2fd20095c","title":"Elastic properties of polyunsaturated phosphatidylethanolamines influence rhodopsin function","year":2012,"lang":"en","type":"article","venue":"Faraday Discussions","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Brock University","funders":"National Institutes of Health","keywords":"Rhodopsin; Polyunsaturated fatty acid; Chemistry; Elasticity (physics); Membrane; Curvature; Monolayer; Biophysics; Phospholipid; Crystallography; Materials science; Biochemistry; Biology; Fatty acid","score_opus":0.012376228474662113,"score_gpt":0.22267500079545607,"score_spread":0.21029877232079397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072864645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936741,0.0024612106,0.0030759082,0.000065553446,0.00042768475,0.00012579151,0.000009667725,0.000016415719,0.00014367673],"genre_scores_gemma":[0.9983032,0.000053170006,0.0003772298,0.00006191828,0.00017168433,0.000017360762,0.000040196264,0.00001783125,0.00095743465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992158,0.000052980282,0.0002027712,0.00015947717,0.00012709819,0.00024187926],"domain_scores_gemma":[0.99953634,0.000005774004,0.0000907066,0.0002055183,0.00007206682,0.00008957359],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011280929,0.0001328713,0.00013197496,0.00003651741,0.000099071265,0.0000113054675,0.000103589926,0.0001096006,0.000082827246],"category_scores_gemma":[0.00010725776,0.00008140565,0.000068799396,0.00011997247,0.000055683504,0.000014896399,0.000057177524,0.00006513867,0.00001201062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054616055,0.00006664732,0.0013366477,0.00001689859,0.00002538859,9.470358e-8,0.00012193926,0.00008774412,0.9968357,0.00026967478,0.00017122565,0.0010134253],"study_design_scores_gemma":[0.00017232617,0.00011799726,0.00765083,0.00006417563,0.000027497766,0.0000040899718,0.0002621421,0.0000395459,0.9861469,0.000024924986,0.0053397124,0.00014980322],"about_ca_topic_score_codex":0.00001828038,"about_ca_topic_score_gemma":0.0000032754406,"teacher_disagreement_score":0.010688744,"about_ca_system_score_codex":0.0000064651063,"about_ca_system_score_gemma":0.000033733904,"threshold_uncertainty_score":0.3319626},"labels":[],"label_agreement":null},{"id":"W2073045947","doi":"10.1111/j.1601-183x.2011.00686.x","title":"VAChT knock-down mice show normal prepulse inhibition but disrupted long-term habituation","year":2011,"lang":"en","type":"article","venue":"Genes Brain & Behavior","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cholinergic; Prepulse inhibition; Habituation; Vesicular acetylcholine transporter; Neuroscience; Acetylcholine; Neurotransmitter; Cholinergic neuron; Mecamylamine; Endocrinology; Chemistry; Choline acetyltransferase; Internal medicine; Nicotinic agonist; Biology; Medicine; Central nervous system","score_opus":0.02228873756648942,"score_gpt":0.252990454925135,"score_spread":0.23070171735864559,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073045947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912942,0.00052933785,0.0071224705,0.000033232816,0.00035439266,0.00043073087,0.000046394238,0.00004111418,0.00014813883],"genre_scores_gemma":[0.9953901,0.000077480676,0.0015905321,0.00018848272,0.0003422825,0.00016259203,0.00079112384,0.000045436343,0.001411933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858713,0.00008448018,0.00031005137,0.00049123866,0.00018351286,0.0003435723],"domain_scores_gemma":[0.99925333,0.000010200522,0.00012328078,0.0003648129,0.00012026427,0.0001281241],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021993315,0.00024040828,0.00016231583,0.00006453712,0.00015249863,0.000042053023,0.00016808794,0.0002611478,0.0007508934],"category_scores_gemma":[0.000038636117,0.00024282836,0.00015071244,0.00008464279,0.00005155631,0.000018617915,0.00012137097,0.000098851204,0.00004752896],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067901376,0.00018170796,0.01687601,0.000014330058,0.000018452203,0.000023091161,0.00021710667,0.00000544536,0.9560427,0.00001855293,0.00016643539,0.026368286],"study_design_scores_gemma":[0.0005072563,0.00026675922,0.06988811,0.000019521556,0.00007363027,0.000054259428,0.000074625124,0.000019966958,0.9283839,0.000010339665,0.00038292486,0.00031871407],"about_ca_topic_score_codex":0.000054789096,"about_ca_topic_score_gemma":0.000086011554,"teacher_disagreement_score":0.0530121,"about_ca_system_score_codex":0.000022909611,"about_ca_system_score_gemma":0.00005169804,"threshold_uncertainty_score":0.9902253},"labels":[],"label_agreement":null},{"id":"W2073439434","doi":"10.1159/000138808","title":"Modulation of Acetylcholine-Stimulated Insulin Release by Glucose and Gastric Inhibitory Polypeptide","year":2008,"lang":"en","type":"article","venue":"Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Medical Council of Canada","funders":"","keywords":"Acetylcholine; Internal medicine; Endocrinology; Gastric inhibitory polypeptide; Muscarinic acetylcholine receptor; Insulin; Cholinergic; Hexamethonium; Atropine; Muscarinic acetylcholine receptor M3; Chemistry; Pancreatic polypeptide; Inhibitory postsynaptic potential; Biology; Receptor; Medicine; Glucagon","score_opus":0.010303973278941407,"score_gpt":0.2482057273811768,"score_spread":0.23790175410223538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073439434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99515694,0.0025373031,0.0018424658,0.000056165314,0.0001817047,0.00013890062,0.00001994525,0.000012023194,0.000054521843],"genre_scores_gemma":[0.9970921,0.0015685548,0.0006090606,0.00026508546,0.00018385059,0.000009262924,0.000099968645,0.000016997717,0.00015512045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922246,0.000073177136,0.00021933731,0.00023886656,0.00007350062,0.00017267907],"domain_scores_gemma":[0.99963576,0.000014406552,0.000101779326,0.00009127741,0.00006745757,0.000089344634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009300465,0.000116604635,0.00015034189,0.000053312127,0.00006358893,0.000002372598,0.00007112055,0.0001305221,0.00012926402],"category_scores_gemma":[0.000026020734,0.00011961572,0.000041707513,0.0000851102,0.00008181737,0.0000049379923,0.0000601572,0.000090446316,0.00000408182],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000235481,0.00007572519,0.00060905924,0.000009625112,0.000034685185,0.000003930979,0.000035822704,0.0007497884,0.9928905,0.0000035409762,0.0039576897,0.0013942001],"study_design_scores_gemma":[0.0014119112,0.00022065251,0.00041765266,0.0000033304682,0.00002128669,0.00003491884,0.00000904297,0.0042059883,0.9892143,0.000013113048,0.0043335655,0.00011421061],"about_ca_topic_score_codex":0.000022705373,"about_ca_topic_score_gemma":5.7237634e-7,"teacher_disagreement_score":0.0036761241,"about_ca_system_score_codex":0.000009421326,"about_ca_system_score_gemma":0.000041590443,"threshold_uncertainty_score":0.48777872},"labels":[],"label_agreement":null},{"id":"W2073570653","doi":"10.1016/j.cellsig.2014.02.021","title":"C5L2 is required for C5a-triggered receptor internalization and ERK signaling","year":2014,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Taipei Veterans General Hospital; Yen Tjing Ling Medical Foundation; National Science Council; Ministry of Education","keywords":"Internalization; MAPK/ERK pathway; Cell biology; Signal transduction; C5a receptor; Receptor; Chemistry; Biology; Immunology; Biochemistry; Complement system","score_opus":0.012697873345349277,"score_gpt":0.2277137690346701,"score_spread":0.21501589568932084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073570653","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.39161953,0.0010326573,0.6066865,0.00004624006,0.00024339263,0.00023014478,0.000008889949,0.000022468397,0.00011020487],"genre_scores_gemma":[0.9828551,0.00013577628,0.01472457,0.00038816172,0.00085086277,0.000039342107,0.00024310351,0.00006821411,0.000694876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847955,0.00008391146,0.0003732394,0.00056111894,0.0001644914,0.0003376824],"domain_scores_gemma":[0.99925286,0.000048675556,0.00017672489,0.00023106925,0.00015746668,0.00013320179],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065176026,0.00024043582,0.00024617653,0.000069738846,0.00020650055,0.0001022333,0.00019544017,0.00022986073,0.00015169363],"category_scores_gemma":[0.00012287931,0.00024433,0.00015214387,0.0000808385,0.000042552772,0.000011070691,0.0000708654,0.00008663736,0.000010648014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008510475,0.000018853669,0.00007441551,0.00006035113,0.000054788354,4.2130793e-7,0.00014549242,0.00030276246,0.9949924,0.00073226704,0.00038777138,0.0031454063],"study_design_scores_gemma":[0.00067804055,0.00028275844,0.000001197329,0.00008341283,0.000037502068,0.000002368153,0.000069649424,0.011075345,0.9491724,0.0013449383,0.036941838,0.0003105596],"about_ca_topic_score_codex":0.0000068752647,"about_ca_topic_score_gemma":0.0000012122116,"teacher_disagreement_score":0.5919619,"about_ca_system_score_codex":0.000015651476,"about_ca_system_score_gemma":0.000029548426,"threshold_uncertainty_score":0.99634886},"labels":[],"label_agreement":null},{"id":"W2073641598","doi":"10.1016/j.regpep.2003.10.009","title":"Capsaicin-sensitive neural pathway mediates atrial natriuretic factor (ANF) release in response to physiological stimuli","year":2003,"lang":"en","type":"article","venue":"Regulatory Peptides","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Distension; Internal medicine; Capsaicin; Endocrinology; Secretion; Atrial Appendage; Atrial natriuretic peptide; Cholinergic; Atrium (architecture); Chemistry; Medicine; Biology; Atrial fibrillation; Receptor","score_opus":0.01901143358069436,"score_gpt":0.2541156934440988,"score_spread":0.23510425986340444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073641598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985109,0.00055081537,0.00012882904,0.00007513028,0.00028931533,0.00032997128,0.000034120647,0.000025181831,0.00005570934],"genre_scores_gemma":[0.9984145,0.000021622624,0.0005193721,0.00028984045,0.00035170125,0.000013348108,0.000031923777,0.00003553674,0.00032214294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979044,0.0005091079,0.00033618123,0.000585887,0.00022691913,0.0004374608],"domain_scores_gemma":[0.9991528,0.00009121502,0.000086422544,0.0003467596,0.0000891461,0.00023369958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047705267,0.00027644815,0.00031418368,0.000103006096,0.000092275885,0.000027460077,0.00015333838,0.00026343088,0.00014178509],"category_scores_gemma":[0.0009805231,0.00024500443,0.000219218,0.00015538004,0.00008855036,0.00000756449,0.00006511097,0.00016990713,0.00003228478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010124268,0.000038323047,0.0004939884,0.000007815233,0.000022072983,0.00003235373,0.00015254064,0.002096022,0.99517477,0.00011799964,0.00037989003,0.00047180365],"study_design_scores_gemma":[0.0011940019,0.0009153429,0.02080408,0.000034258763,0.0000127838175,0.000013960299,0.000310059,0.00017068071,0.9733228,0.00013921004,0.002615092,0.00046770566],"about_ca_topic_score_codex":0.000012080098,"about_ca_topic_score_gemma":0.00001589368,"teacher_disagreement_score":0.021851938,"about_ca_system_score_codex":0.00005386213,"about_ca_system_score_gemma":0.00012809789,"threshold_uncertainty_score":0.999099},"labels":[],"label_agreement":null},{"id":"W2073745171","doi":"10.1016/j.coph.2014.05.006","title":"Editorial overview: Respiratory: GPCR signaling and the lung","year":2014,"lang":"en","type":"editorial","venue":"Current Opinion in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"G protein-coupled receptor; Signal transduction; Neuroscience; Biology; Agonist; Functional selectivity; Computational biology; Receptor; Bioinformatics; Cell biology; Biochemistry","score_opus":0.023918946436128696,"score_gpt":0.35755368198688764,"score_spread":0.33363473555075895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073745171","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00038155745,0.05939726,0.0003079428,0.00008002882,0.93920547,0.0005249205,0.0000576083,0.000014503823,0.00003068388],"genre_scores_gemma":[0.00039679647,0.018592745,0.000019721438,0.00008458135,0.98008645,0.00022626457,0.0004916845,0.000058285543,0.00004348551],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968994,0.0008529343,0.00058957265,0.00076132297,0.00044572065,0.00045104962],"domain_scores_gemma":[0.9986102,0.00041073633,0.00036791305,0.00028898488,0.00020910866,0.00011306039],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001864888,0.00042166864,0.00057119416,0.00011609903,0.00015587588,0.00006367907,0.00049710844,0.0010362475,0.00013290708],"category_scores_gemma":[0.000407401,0.00033345874,0.00017842933,0.000106976695,0.00022927613,0.0000058773503,0.00037735995,0.0011583818,0.000008547419],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004927983,0.000037020676,0.000010513513,0.0003072405,0.000067785695,2.1539753e-7,0.00004172081,0.00004527438,0.014303367,0.000106694584,0.9838983,0.0006890607],"study_design_scores_gemma":[0.0049076327,0.00014737312,6.1966375e-7,0.00016110428,0.00006532469,6.655461e-7,0.000009182814,0.0001594199,0.003249169,0.00016345143,0.99077475,0.00036128686],"about_ca_topic_score_codex":0.000011157221,"about_ca_topic_score_gemma":0.000001385718,"teacher_disagreement_score":0.04088094,"about_ca_system_score_codex":0.00005217726,"about_ca_system_score_gemma":0.0003055608,"threshold_uncertainty_score":0.9999117},"labels":[],"label_agreement":null},{"id":"W2073977861","doi":"10.1210/en.2005-1315","title":"Role of Tyrosine Kinase Receptors in Angiotensin II AT2 Receptor Signaling: Involvement in Neurite Outgrowth and in p42/p44mapk Activation in NG108-15 Cells","year":2006,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Neurite; Nerve growth factor; Endocrinology; Internal medicine; Tropomyosin receptor kinase A; Receptor; Tyrosine kinase; Epidermal growth factor; Angiotensin II; MAPK/ERK pathway; Tyrosine phosphorylation; Cell biology; Low-affinity nerve growth factor receptor; Chemistry; Biology; Phosphorylation; Medicine; Biochemistry; In vitro","score_opus":0.0073677144521455745,"score_gpt":0.21053673097351552,"score_spread":0.20316901652136996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073977861","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99814665,0.0010495373,0.00005568091,0.00019673396,0.00014909984,0.0003030365,0.00000600468,0.0000071255545,0.000086100124],"genre_scores_gemma":[0.99836916,0.0002723913,0.0009395843,0.00008242847,0.00010024605,0.000032361902,0.0001051785,0.000024160947,0.0000744887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982054,0.000170021,0.00057227013,0.00048942876,0.00010635869,0.00045650118],"domain_scores_gemma":[0.99956375,0.000025500141,0.00014065247,0.00019240756,0.00003868498,0.00003898196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021340331,0.00021371781,0.00034546756,0.0004150938,0.00002543596,0.000008665298,0.00012804002,0.00021231815,0.000044868706],"category_scores_gemma":[0.000044321285,0.0002341339,0.00004880297,0.00030824612,0.000067236535,0.0000133014755,0.00014501865,0.00022078774,0.0000016754394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018976783,0.00027804228,0.028300242,0.00001525384,0.000005671583,0.000009137973,0.00019654544,0.0009912213,0.9683137,0.00018121199,0.00009032884,0.0014288753],"study_design_scores_gemma":[0.0016365886,0.00034967138,0.010384569,0.0000675988,0.0000029506773,0.0000023238704,0.0002678719,0.00016391813,0.984403,0.00054264837,0.0019649584,0.00021388245],"about_ca_topic_score_codex":0.0022098485,"about_ca_topic_score_gemma":0.0021856078,"teacher_disagreement_score":0.017915675,"about_ca_system_score_codex":0.0000648845,"about_ca_system_score_gemma":0.00004393973,"threshold_uncertainty_score":0.9547703},"labels":[],"label_agreement":null},{"id":"W2074177825","doi":"10.1016/j.pscychresns.2007.09.002","title":"Automated gray level index measurements reveal only minor cytoarchitectonic changes of Brodmann area 9 in schizophrenia","year":2008,"lang":"en","type":"article","venue":"Psychiatry Research Neuroimaging","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cytoarchitecture; Gray (unit); Schizophrenia (object-oriented programming); Psychology; Neuropil; Anatomy; Neuroscience; Medicine; Nuclear medicine; Central nervous system; Psychiatry","score_opus":0.12147919053501836,"score_gpt":0.34503096008457546,"score_spread":0.22355176954955708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074177825","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99670976,0.00108746,0.00023635649,0.00059336016,0.00034526206,0.00038287207,0.000024857007,0.00004906457,0.00057099626],"genre_scores_gemma":[0.9968141,0.0001619818,0.0022644775,0.00011371308,0.00021377947,0.000031081363,0.000039673356,0.00005547823,0.00030574625],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969225,0.00043665332,0.00039916346,0.0006824752,0.0007979941,0.0007612317],"domain_scores_gemma":[0.9988848,0.000029920286,0.00011967347,0.0005508398,0.00025322687,0.00016154852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011020863,0.00024440032,0.00028640727,0.00050885574,0.00022149709,0.00003120303,0.00053096184,0.00012294731,0.000038103593],"category_scores_gemma":[0.00019330918,0.00024396834,0.000107661406,0.0006098949,0.00021361075,0.000011073394,0.00024499,0.00051110785,0.000008792471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038181667,0.00018841,0.1255805,0.00008657839,0.000037582147,0.000016804483,0.00010718655,0.00013150398,0.8691168,0.00001828402,0.0018842054,0.0024503588],"study_design_scores_gemma":[0.009729774,0.002291613,0.4350834,0.00082341785,0.00003525185,0.0005130785,0.00048851885,0.007806909,0.53762203,0.0010478001,0.002986639,0.0015715908],"about_ca_topic_score_codex":0.00022473403,"about_ca_topic_score_gemma":0.0005561457,"teacher_disagreement_score":0.33149472,"about_ca_system_score_codex":0.000032258424,"about_ca_system_score_gemma":0.0005051233,"threshold_uncertainty_score":0.994874},"labels":[],"label_agreement":null},{"id":"W2074195579","doi":"10.1016/j.ydbio.2011.05.233","title":"The Aplnr GPCR signals independently of Gai/o proteins and cell-non-autonomously in the development of myocardial progenitor cells","year":2011,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; G protein-coupled receptor; Progenitor cell; Cell biology; Progenitor; Cell; Computational biology; Genetics; Signal transduction; Stem cell","score_opus":0.015207855984230082,"score_gpt":0.21932413809086737,"score_spread":0.2041162821066373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074195579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971656,0.00032415878,0.0007250381,0.000009721934,0.00013827386,0.0005715558,0.000009572443,0.0000029237776,0.001053161],"genre_scores_gemma":[0.98991245,0.00006370347,0.009741084,0.000046537127,0.00003565718,0.00010866552,0.000029522203,0.000012208161,0.000050199167],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987324,0.00012780826,0.0004899956,0.00027256671,0.00010949806,0.00026777218],"domain_scores_gemma":[0.9995425,0.000028548831,0.00018814424,0.00014919198,0.000052685453,0.000038958286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071491586,0.00016830569,0.00020518024,0.000047567544,0.00011501101,0.000008934828,0.00034118845,0.00017702638,0.00002418055],"category_scores_gemma":[0.000015926169,0.00010513444,0.00005677655,0.0000840177,0.00015721946,0.000003858827,0.0001816573,0.00009815547,0.000003831468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009064098,0.00007343845,0.004564462,0.000017282744,0.000054597498,0.0000010877264,0.0026189152,5.4224876e-7,0.987628,0.00006914172,0.00002414214,0.004857795],"study_design_scores_gemma":[0.00039455394,0.00023923321,0.0034439727,0.0000099980725,0.0000064073506,0.0000069985335,0.0016785823,0.0000025154945,0.9918313,0.00011324166,0.00213187,0.00014130643],"about_ca_topic_score_codex":0.000033891323,"about_ca_topic_score_gemma":0.000059536826,"teacher_disagreement_score":0.009016045,"about_ca_system_score_codex":0.000017057562,"about_ca_system_score_gemma":0.0002835632,"threshold_uncertainty_score":0.4287258},"labels":[],"label_agreement":null},{"id":"W2074571847","doi":"10.1074/jbc.m700577200","title":"Unraveling G Protein-coupled Receptor Endocytosis Pathways Using Real-time Monitoring of Agonist-promoted Interaction between β-Arrestins and AP-2","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"","keywords":"Endocytosis; Agonist; G protein-coupled receptor; Chemistry; Cell biology; Receptor; Biology; Biochemistry","score_opus":0.04082475389361589,"score_gpt":0.281632119257276,"score_spread":0.2408073653636601,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074571847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961406,0.00029221157,0.0032594092,0.000009856964,0.000106360465,0.00009716232,0.000010416374,0.000008350413,0.00007562828],"genre_scores_gemma":[0.9857423,0.00019361984,0.01301229,0.0000033700137,0.0009912857,0.0000012252785,0.000020980922,0.000016430235,0.000018555085],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856424,0.0000450522,0.00070849876,0.00024221776,0.00017826326,0.0002617339],"domain_scores_gemma":[0.9986959,0.00006322238,0.0007029187,0.00013428304,0.00024166655,0.00016198347],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008148294,0.00019424928,0.00037481563,0.000039551895,0.00008454469,0.00002445179,0.00017275645,0.00033826596,0.00006140506],"category_scores_gemma":[0.00034854814,0.00015409282,0.00016397082,0.00009183531,0.00007733804,0.000010069701,0.00009229375,0.00026437896,6.0950214e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002286099,0.000044123204,0.004071852,0.000042939315,0.00007258023,0.000008365917,0.000028509507,0.000022988599,0.99384356,0.0000010662761,0.0000022334652,0.0016331543],"study_design_scores_gemma":[0.00042758105,0.0003796342,0.0006926093,0.00018703255,0.00003088899,0.000065722124,0.0002511975,0.00007563787,0.99759454,0.00003870076,0.00008973472,0.00016674647],"about_ca_topic_score_codex":0.00000951786,"about_ca_topic_score_gemma":8.567335e-8,"teacher_disagreement_score":0.010398361,"about_ca_system_score_codex":0.000049090333,"about_ca_system_score_gemma":0.00006156392,"threshold_uncertainty_score":0.6283723},"labels":[],"label_agreement":null},{"id":"W2074585362","doi":"10.1111/j.1742-4658.2009.07162.x","title":"Mutagenic probes of the role of Ser209 on the cavity shaping loop of human monoamine oxidase A","year":2009,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Science Foundation","keywords":"Mutant; Monoamine oxidase; Biochemistry; Wild type; Monoamine oxidase A; Enzyme; Monoamine neurotransmitter; Monoamine oxidase B; Chemistry; Phosphorylation; Biology; Gene; Receptor","score_opus":0.015181699629094962,"score_gpt":0.2452857067108475,"score_spread":0.23010400708175255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074585362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985985,0.0006753545,0.00014540889,0.00010690039,0.000042876167,0.00009319515,0.000005495925,0.0000011245277,0.0003311412],"genre_scores_gemma":[0.99957824,0.000040218125,0.00010995728,0.00006837066,0.000101876576,9.814318e-7,0.000001726454,0.000006285127,0.00009232164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992929,0.00008127774,0.00026434555,0.0000886214,0.00015747124,0.00011536406],"domain_scores_gemma":[0.99935734,0.000008933778,0.0002946398,0.00020789236,0.00010088492,0.000030297255],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034239044,0.000082922714,0.00013391217,0.000023210794,0.00009940955,0.000009033877,0.0002570599,0.000061957595,0.00006592056],"category_scores_gemma":[0.000049104157,0.00004611052,0.00016319226,0.000059509715,0.000042692755,0.0000027478454,0.0000387321,0.00013601751,3.0461314e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003515999,0.00007138338,0.00035829566,0.000006122724,0.000030738418,5.0450166e-7,0.00010899218,0.0001224109,0.99694145,0.00043937104,0.000047404024,0.0018381417],"study_design_scores_gemma":[0.0002086548,0.0004952309,0.0018310775,0.00007082873,0.000017491333,0.000017326669,0.00017077758,0.000075220014,0.99551773,0.0013960237,0.00014940639,0.000050210354],"about_ca_topic_score_codex":0.000009551574,"about_ca_topic_score_gemma":0.0000040485,"teacher_disagreement_score":0.0017879313,"about_ca_system_score_codex":0.000006347097,"about_ca_system_score_gemma":0.00003936496,"threshold_uncertainty_score":0.18803324},"labels":[],"label_agreement":null},{"id":"W2074603505","doi":"10.1159/000233053","title":"Bordetella pertussis-Induced Impairment of Relaxation of Rat Trachea to Isoprenaline and Histamine and Its Reversal with Hydrocortisone","year":2009,"lang":"en","type":"article","venue":"International Archives of Allergy and Applied Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Bordetella pertussis; Histamine; Isoprenaline; Carbachol; Contraction (grammar); Internal medicine; Endocrinology; Hydrocortisone; Medicine; Chemistry; Biology; Stimulation; Bacteria","score_opus":0.00456540743616492,"score_gpt":0.20812069728380994,"score_spread":0.203555289847645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074603505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965245,0.0006750144,0.0020161371,0.00025538434,0.000027458278,0.000107695996,0.0000062982344,0.000002024058,0.0003854953],"genre_scores_gemma":[0.99697804,0.0008367813,0.0019880075,0.000041364292,0.000020878051,0.0000053147614,0.000034345365,0.0000051999536,0.00009007994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99945253,0.000014963136,0.00021618622,0.00017666473,0.000062752224,0.0000769088],"domain_scores_gemma":[0.9997095,0.000018600223,0.00014372815,0.00006713284,0.000032846772,0.00002823476],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000042476186,0.00008980135,0.00015904874,0.000067484725,0.000019378205,0.0000026163489,0.00007026337,0.000051641127,0.000010765101],"category_scores_gemma":[0.00001167223,0.00007604514,0.000020156887,0.000022840086,0.00005931264,0.0000034545506,0.00005189599,0.00004399629,5.987349e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012669825,0.00007716671,0.00004291265,0.000008307005,0.00015793466,3.9831153e-7,0.00029096816,0.000060245668,0.9768367,0.0026025332,0.0000034050581,0.018652435],"study_design_scores_gemma":[0.0010113438,0.0018702484,0.008812905,0.00003750856,0.00000948993,0.000015948468,0.000121922596,0.00028919068,0.98685,0.00048508606,0.00040771675,0.00008862893],"about_ca_topic_score_codex":0.000011669522,"about_ca_topic_score_gemma":0.000007416805,"teacher_disagreement_score":0.018563807,"about_ca_system_score_codex":0.000002393699,"about_ca_system_score_gemma":0.000013842924,"threshold_uncertainty_score":0.31010306},"labels":[],"label_agreement":null},{"id":"W2074988439","doi":"10.3109/09537100903137314","title":"The platelet protein kinase C substrate pleckstrin binds directly to SDPR protein","year":2009,"lang":"en","type":"article","venue":"Platelets","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Pleckstrin homology domain; IRS1; Platelet activation; Cell biology; Protein kinase C; Biochemistry; Phosphorylation; Biology; Chemistry; Platelet; Insulin receptor; Endocrinology; Insulin; Immunology","score_opus":0.008459379284593898,"score_gpt":0.23038291512098572,"score_spread":0.22192353583639182,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2074988439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996006,0.00041856917,0.00051879534,0.0007388836,0.00011280657,0.00092013733,0.000013235271,0.000043726646,0.0012278601],"genre_scores_gemma":[0.9958475,0.000031325213,0.00087064254,0.00027180996,0.0002556311,0.000112291695,0.000048238537,0.000029224506,0.0025333262],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838114,0.00007266834,0.00029868013,0.00046556233,0.00023177754,0.0005501551],"domain_scores_gemma":[0.9991907,0.000011016128,0.000091968795,0.0004302614,0.0000784412,0.00019762808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037227236,0.00026075554,0.00018491872,0.000046936093,0.00029534084,0.00013227687,0.00037016268,0.00019176294,0.000060087736],"category_scores_gemma":[0.00009859386,0.00019551981,0.00010446877,0.00017899374,0.00003092997,0.0000064117435,0.000061175444,0.00017863086,0.00008315037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019741211,0.000041174597,0.000006339454,0.0000049644586,0.000022996208,0.000037700647,0.00003073792,0.000054566182,0.9727806,0.0005070259,0.0006171048,0.025699394],"study_design_scores_gemma":[0.00038197995,0.0005969737,0.00011715996,0.000032209133,0.000003184863,0.000015935344,0.000024096173,0.00003648935,0.9250661,0.00041311444,0.073040865,0.00027190652],"about_ca_topic_score_codex":0.000016438444,"about_ca_topic_score_gemma":0.000027845217,"teacher_disagreement_score":0.07242376,"about_ca_system_score_codex":0.000020303625,"about_ca_system_score_gemma":0.00007069193,"threshold_uncertainty_score":0.79730666},"labels":[],"label_agreement":null},{"id":"W2075027558","doi":"10.1177/108705710200700203","title":"Considerations for Using Fluorescence Polarization in the Screening of G Protein-Coupled Receptors","year":2002,"lang":"en","type":"article","venue":"SLAS DISCOVERY","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"PerkinElmer Biosignal","funders":"","keywords":"TRACER; Fluorescence; Fluorescence anisotropy; Computer science; Chemistry; Biological system; Physics; Biology; Optics","score_opus":0.03720925362219081,"score_gpt":0.25607253277936165,"score_spread":0.21886327915717085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075027558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87026,0.00023243787,0.12887746,0.00006921294,0.00007365803,0.00041880776,0.000012359406,0.0000027398105,0.000053318283],"genre_scores_gemma":[0.9861788,0.000010317763,0.01349086,0.000063017724,0.000079438825,0.000026262476,0.000026528372,0.000010120189,0.000114649134],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994202,0.00004597188,0.00017436463,0.0001502805,0.00008772108,0.000121420424],"domain_scores_gemma":[0.9997026,0.00002676234,0.00007702388,0.00013810174,0.000043166998,0.000012397609],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018419548,0.00007359357,0.000082048384,0.000031869728,0.000084364874,0.000038732942,0.00007431568,0.000064567845,0.000039864655],"category_scores_gemma":[0.00017404139,0.00005851668,0.000058031,0.00007628585,0.00003132905,0.000014194985,0.000019068231,0.000042524134,3.6809377e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014500887,0.00003057287,0.0003699469,0.00001162405,0.000009799521,2.7016182e-7,0.0001300745,0.0005635022,0.995509,0.0031200345,0.00004354739,0.00019710202],"study_design_scores_gemma":[0.00051746157,0.0001767041,0.00011909785,0.00006401896,0.000015590493,0.00000474565,0.0005058482,0.027299028,0.96960086,0.0012979095,0.00024343259,0.0001552946],"about_ca_topic_score_codex":0.000031529114,"about_ca_topic_score_gemma":0.000021177553,"teacher_disagreement_score":0.11591879,"about_ca_system_score_codex":0.000005644135,"about_ca_system_score_gemma":0.000021474818,"threshold_uncertainty_score":0.2386241},"labels":[],"label_agreement":null},{"id":"W2075030347","doi":"10.1016/j.ygcen.2006.01.012","title":"Teneurin C-terminal associated peptides: An enigmatic family of neuropeptides with structural similarity to the corticotropin-releasing factor and calcitonin families of peptides","year":2006,"lang":"en","type":"review","venue":"General and Comparative Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Ottawa; Toronto Zoo","funders":"","keywords":"Biology; Gene; Phylogenetic tree; Genetics; Sequence (biology); Phylogenetics; Neuropeptide; Peptide sequence; Calcitonin; Gene family; Structural similarity; Peptide; Evolutionary biology; Computational biology; Genome; Endocrinology; Biochemistry; Receptor","score_opus":0.06104674383188906,"score_gpt":0.32306497819594515,"score_spread":0.2620182343640561,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075030347","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6945247,0.30476004,0.000102355814,0.0000053506446,0.00006387422,0.00037724033,0.00012736711,0.000006901213,0.000032139546],"genre_scores_gemma":[0.46558213,0.53275687,0.0010656734,0.00004698718,0.00015065855,0.00004616654,0.00018884697,0.00003189849,0.00013076384],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99779755,0.00047953118,0.0006320686,0.00054777344,0.00016257894,0.00038048468],"domain_scores_gemma":[0.9989398,0.00006820074,0.00045627911,0.00029073478,0.00015333951,0.00009165355],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000023788662,0.00047684982,0.0013930467,0.00010416738,0.00015350006,0.000035778325,0.00026594196,0.00015231039,0.0000049510318],"category_scores_gemma":[0.000026568336,0.00029253232,0.00014855007,0.00012510332,0.00036101157,0.000009894644,0.0001985709,0.00023738688,4.7824125e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006215163,0.00038261132,0.0039303936,0.0053387736,0.0024857009,0.000098791425,0.0019814621,0.0012572848,0.35088018,0.0019678215,0.0004249009,0.63063055],"study_design_scores_gemma":[0.008181453,0.04114282,0.14426127,0.011016381,0.0066650584,0.0034131017,0.0065466654,0.0030580694,0.23945177,0.00060544343,0.5261454,0.009512586],"about_ca_topic_score_codex":0.00027229948,"about_ca_topic_score_gemma":0.00028391238,"teacher_disagreement_score":0.621118,"about_ca_system_score_codex":0.000014393834,"about_ca_system_score_gemma":0.000101433536,"threshold_uncertainty_score":0.9999527},"labels":[],"label_agreement":null},{"id":"W2075177638","doi":"10.1177/108705710000500308","title":"Fluorescence Polarization Assays for High Throughput Screening of G Protein–Coupled Receptors","year":2000,"lang":"en","type":"article","venue":"SLAS DISCOVERY","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BioPhage Pharma (Canada)","funders":"","keywords":"Fluorescence anisotropy; Tartrazine; High-throughput screening; Fluorescence; Chemistry; Polarization (electrochemistry); Chromatography; Combinatorial chemistry; Analytical Chemistry (journal); Biophysics; Biology; Biochemistry; Optics","score_opus":0.009107803679068133,"score_gpt":0.22953085524209835,"score_spread":0.22042305156303021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075177638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8450697,0.00020945251,0.15384088,0.000041213967,0.0001504269,0.00043482412,0.000040495455,0.000012464239,0.00020050237],"genre_scores_gemma":[0.97931355,0.000059190672,0.016872287,0.000047554822,0.00023626784,0.000045662684,0.00032828838,0.0000301102,0.0030670809],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906135,0.00003459705,0.00023711278,0.00030819638,0.00014503718,0.00021370576],"domain_scores_gemma":[0.99955773,0.000010868457,0.000099043275,0.00022864601,0.00006672719,0.00003700817],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017732548,0.00013930908,0.00015884897,0.000026471042,0.00008656352,0.00003709061,0.00015118484,0.00013963925,0.00023065969],"category_scores_gemma":[0.00005912817,0.00013000051,0.000109475564,0.000086289634,0.000043367636,0.000022504508,0.00003231696,0.00005323193,0.0000036243136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017761046,0.00003878724,0.00026273626,0.00002806855,0.00003805127,2.3012502e-7,0.00002682951,0.00028203428,0.990311,0.0020919302,0.00013190348,0.006610775],"study_design_scores_gemma":[0.00053660234,0.0003551065,0.00018688694,0.00006009106,0.000018015997,0.000001076315,0.00004854478,0.00067472615,0.9946293,0.00092438125,0.002376345,0.00018890521],"about_ca_topic_score_codex":0.0000760806,"about_ca_topic_score_gemma":0.000007258025,"teacher_disagreement_score":0.1369686,"about_ca_system_score_codex":0.00000856501,"about_ca_system_score_gemma":0.000051573206,"threshold_uncertainty_score":0.5301267},"labels":[],"label_agreement":null},{"id":"W2075201303","doi":"10.1007/s00221-013-3818-4","title":"The role of serotonin in memory: interactions with neurotransmitters and downstream signaling","year":2014,"lang":"en","type":"review","venue":"Experimental Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Serotonergic; Neuroscience; Serotonin; Glutamatergic; Neurotransmitter; Cholinergic; Dopaminergic; 5-HT receptor; Dopamine; Neurotransmission; Acetylcholine; Glutamate receptor; Chemistry; Psychology; Receptor; Biology; Central nervous system; Endocrinology; Biochemistry","score_opus":0.03582677309832778,"score_gpt":0.3827120026105805,"score_spread":0.34688522951225276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075201303","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013565332,0.9848542,0.000023651575,0.000040029354,0.00004581292,0.00084120047,0.000007468014,0.000003883986,0.0006184153],"genre_scores_gemma":[0.05984111,0.9386022,0.00024428015,0.000028536893,0.00016290326,0.00057543715,0.00006878296,0.00007697951,0.00039975354],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99808234,0.00059324474,0.00031113654,0.00040842273,0.0002760651,0.00032878638],"domain_scores_gemma":[0.9992159,0.00025666083,0.000094143084,0.00031119664,0.000044626493,0.00007748971],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008733168,0.0002104318,0.00041943384,0.00012669116,0.0001677475,0.00006399685,0.0002985647,0.00012638654,0.00003492489],"category_scores_gemma":[0.000046730827,0.00013600208,0.000115308416,0.00017192055,0.0002270045,0.000004248353,0.00015587102,0.00040722874,0.0000029451683],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011790866,0.0000985993,0.000010696369,0.0007273932,0.000120386874,0.0000062749996,0.00031402192,0.000007939998,0.5972638,0.0001978384,0.00017271041,0.4009624],"study_design_scores_gemma":[0.00022284471,0.00046667337,4.4459776e-7,0.001303253,0.000009055429,0.000025848196,0.0013105619,0.000018539718,0.33989167,0.000013754852,0.65658045,0.00015687452],"about_ca_topic_score_codex":0.00007279279,"about_ca_topic_score_gemma":0.000024028966,"teacher_disagreement_score":0.6564078,"about_ca_system_score_codex":0.000030265643,"about_ca_system_score_gemma":0.00011114458,"threshold_uncertainty_score":0.5546004},"labels":[],"label_agreement":null},{"id":"W2075274873","doi":"10.1016/j.mcn.2014.05.007","title":"N-terminal tagging of the dopamine transporter impairs protein expression and trafficking in vivo","year":2014,"lang":"en","type":"article","venue":"Molecular and Cellular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"Canadian Institutes of Health Research","keywords":"Dopamine transporter; Dopamine Plasma Membrane Transport Proteins; Biology; Dopamine; Striatum; Dopaminergic; Cell biology; Messenger RNA; In vivo; Genetically modified mouse; Extracellular; Transgene; Molecular biology; Endocrinology; Biochemistry; Gene; Genetics","score_opus":0.004856632470476158,"score_gpt":0.19463283029927114,"score_spread":0.18977619782879498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075274873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9806567,0.00019883968,0.018829545,0.000042331285,0.00005469151,0.00014803655,0.0000013934789,0.0000034581055,0.00006500159],"genre_scores_gemma":[0.9994945,0.00001200626,0.00026267784,0.00015895265,0.000014717908,0.00000653007,8.5979747e-7,0.00000986254,0.000039926526],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991505,0.000075437325,0.00015243514,0.00031464628,0.00013854202,0.00016844348],"domain_scores_gemma":[0.9996986,0.000003374284,0.00005955261,0.00017742974,0.00001242383,0.000048632755],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023062751,0.000107054075,0.00010388411,0.00003144682,0.00007453902,0.000021307445,0.00014348998,0.00005283816,0.0000034722561],"category_scores_gemma":[0.00002401493,0.00007955324,0.00004383289,0.000085958694,0.00012362843,0.000006023523,0.00006770472,0.00007141605,3.8276827e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009974,0.00001616106,0.00039021717,0.000021621656,4.7304894e-7,0.000007700777,0.00004930845,0.00010810287,0.99851745,0.00006578025,0.0000013839918,0.0008118522],"study_design_scores_gemma":[0.00023575807,0.00012330605,0.00029234757,0.00005293933,0.0000038799244,0.000017847613,0.000024184843,0.0013861749,0.99703455,0.000037158457,0.0006957403,0.000096118216],"about_ca_topic_score_codex":0.0000059320937,"about_ca_topic_score_gemma":0.0000024944513,"teacher_disagreement_score":0.018837763,"about_ca_system_score_codex":0.0000018636712,"about_ca_system_score_gemma":0.000012952675,"threshold_uncertainty_score":0.32440868},"labels":[],"label_agreement":null},{"id":"W2075435221","doi":"10.1186/1710-1492-6-s2-p20","title":"Molecular and morphological characterization of piecemeal degranulation in human neutrophil azurophilic granules","year":2010,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia; University of Manitoba; University of Calgary","funders":"","keywords":"Azurophilic granule; Degranulation; Granule (geology); Cell biology; Secretory Vesicle; Exocytosis; Vesicle; Biology; Chemistry; Myeloperoxidase; Secretion; Biochemistry; Immunology; Membrane; Inflammation","score_opus":0.010224535168168796,"score_gpt":0.26787882245868133,"score_spread":0.25765428729051254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075435221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986357,0.00022460663,0.00067384995,0.00012106978,0.00017146383,0.00009579059,0.0000035432647,0.000006458605,0.00006748598],"genre_scores_gemma":[0.998678,0.00071905437,0.00024482398,0.000105334344,0.00007563044,0.0000075018406,0.00013325243,0.0000122964475,0.000024054953],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988558,0.00013881797,0.00044265809,0.00034230223,0.000054117696,0.00016626633],"domain_scores_gemma":[0.99956435,0.000023026227,0.00013202136,0.00018281037,0.000049190585,0.000048582242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025287212,0.0001280109,0.00024422174,0.00005139594,0.000052292846,0.000009976058,0.000098939396,0.00040982483,0.00005109519],"category_scores_gemma":[0.00006403935,0.00011736577,0.000064801025,0.00005155236,0.00028358033,0.000006122319,0.000105877334,0.00024397588,8.4588964e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000110795656,0.00009726933,0.0039354805,0.00000307987,0.000044121993,0.000007640562,0.00001288875,0.0000031589511,0.9861358,0.0034079931,0.0000010290443,0.0062407684],"study_design_scores_gemma":[0.0022939318,0.001916298,0.58898807,0.000016027689,0.000013973668,0.00008360208,0.00003487222,0.00021624479,0.4012421,0.0017922453,0.0030880012,0.00031461558],"about_ca_topic_score_codex":0.000029307523,"about_ca_topic_score_gemma":0.000058334113,"teacher_disagreement_score":0.5850526,"about_ca_system_score_codex":0.000001562948,"about_ca_system_score_gemma":0.000013668773,"threshold_uncertainty_score":0.47860372},"labels":[],"label_agreement":null},{"id":"W2075796864","doi":"10.1016/j.ymeth.2015.04.010","title":"Quantifying biased signaling in GPCRs using BRET-based biosensors","year":2015,"lang":"en","type":"article","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; McGill University; Université de Montréal; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Québec Consortium for Drug Discovery","keywords":"G protein-coupled receptor; Functional selectivity; Arrestin; Effector; Receptor; HEK 293 cells; Signal transduction; Computational biology; Cell biology; G protein; Chemistry; Biology; Biochemistry","score_opus":0.2228709900754906,"score_gpt":0.43254784975658955,"score_spread":0.20967685968109895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075796864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.64227307,0.00042518417,0.35679016,0.000023871657,0.00026282124,0.000090234054,0.0000022907725,0.000014183102,0.00011819487],"genre_scores_gemma":[0.5723763,0.0000036064862,0.42728367,0.00015141677,0.00010810483,0.0000043133914,0.000015970938,0.00002578462,0.000030819654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983,0.00058458355,0.00029054598,0.00036668015,0.0001449574,0.0003132116],"domain_scores_gemma":[0.99938047,0.000056126082,0.000094521696,0.00025884772,0.00007965228,0.00013036447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022264428,0.0001730682,0.00022005725,0.00013070271,0.00005557923,0.000037256938,0.00015238693,0.0001855955,0.00003214178],"category_scores_gemma":[0.00040631733,0.00016931273,0.0001009573,0.00023697178,0.0000342232,0.000004322829,0.000050064857,0.00011893164,0.0000033030417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005566145,0.000024838198,0.0009342054,0.000011225349,0.000011015933,0.000006763712,0.000064977416,0.012861468,0.9829598,0.00004442161,0.000027496651,0.0029980966],"study_design_scores_gemma":[0.0006691794,0.000100435784,0.000026267413,0.000037150367,0.0000116830115,0.000005132863,0.0002632645,0.027018247,0.96889514,0.0001451804,0.0025962428,0.00023206593],"about_ca_topic_score_codex":0.000110295194,"about_ca_topic_score_gemma":0.000014417343,"teacher_disagreement_score":0.070493534,"about_ca_system_score_codex":0.00003654921,"about_ca_system_score_gemma":0.00014322261,"threshold_uncertainty_score":0.69043726},"labels":[],"label_agreement":null},{"id":"W2076352139","doi":"10.1038/srep00301","title":"The role of GRK6 in animal models of Parkinson's Disease and L-DOPA treatment","year":2012,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse; National Institutes of Health; Compagnia di San Paolo","keywords":"G protein-coupled receptor kinase; Dopamine; Dopamine receptor; Parkinson's disease; Dopamine receptor D2; Kinase; Haloperidol; Receptor; Pharmacology; Medicine; Disease; Neuroscience; Internal medicine; G protein-coupled receptor; Biology; Cell biology","score_opus":0.01006060165408633,"score_gpt":0.22711711561842504,"score_spread":0.2170565139643387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076352139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993467,0.005794142,0.000043156015,0.000008489355,0.00032118443,0.00011386726,0.0000030591498,0.0000014039169,0.0002477162],"genre_scores_gemma":[0.9994739,0.00010566814,0.0001566864,0.0000013793884,0.00003031588,0.000010926961,0.000014023569,0.000004913961,0.00020216628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930537,0.000023556948,0.0002080527,0.00019727467,0.00011616862,0.000149609],"domain_scores_gemma":[0.9994739,0.000005217832,0.00012540557,0.00028227753,0.000038197242,0.00007500102],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004924111,0.00006263,0.000083199964,0.000024044306,0.00006271519,0.00001712452,0.000042425614,0.000022930188,0.000006568911],"category_scores_gemma":[0.000024227096,0.000041486375,0.000045857953,0.000056004174,0.00009826787,0.000006137606,0.000039839244,0.000014719402,1.5195927e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004124127,0.00007463097,0.019533874,0.000005454706,0.000011305268,0.0000039269244,0.00011366204,0.00008038987,0.97589344,0.00031474727,0.000041521376,0.0038858135],"study_design_scores_gemma":[0.00009105551,0.00008921343,0.0018954116,0.0000098127375,0.000012157796,0.000011629917,0.0001609415,0.00034696926,0.96941775,0.0033172134,0.024586737,0.00006109161],"about_ca_topic_score_codex":0.000022643964,"about_ca_topic_score_gemma":0.000009750606,"teacher_disagreement_score":0.024545215,"about_ca_system_score_codex":0.00000630938,"about_ca_system_score_gemma":0.0000476557,"threshold_uncertainty_score":0.16917652},"labels":[],"label_agreement":null},{"id":"W2076727284","doi":"10.1523/jneurosci.4259-09.2009","title":"The Role of Rhodopsin Glycosylation in Protein Folding, Trafficking, and Light-Sensitive Retinal Degeneration","year":2009,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Foundation Fighting Blindness","keywords":"Rhodopsin; Glycosylation; Biology; Endoplasmic reticulum; Golgi apparatus; Cell biology; Retinal degeneration; Mutant; Retinitis pigmentosa; Biochemistry; Retinal; Gene","score_opus":0.00743997740513008,"score_gpt":0.23388647038663282,"score_spread":0.22644649298150274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076727284","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974327,0.00034257353,0.0018582321,0.00018189933,0.00006664238,0.00006435543,2.8096258e-7,7.324512e-7,0.00005254828],"genre_scores_gemma":[0.99919355,0.000096531105,0.0005813652,0.000043860375,0.000065567714,3.805194e-7,1.8946663e-7,0.0000024046838,0.000016155247],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993985,0.000063007545,0.00021249514,0.000095520125,0.00014271603,0.00008775695],"domain_scores_gemma":[0.99960953,0.00000746722,0.00022044063,0.00005368797,0.00008043031,0.000028426924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044770952,0.000049563638,0.00006859383,0.000037549176,0.00007155949,0.00003063491,0.00008348336,0.00003225676,3.7205723e-7],"category_scores_gemma":[0.00016216589,0.00003474075,0.000029067072,0.00008148211,0.00003015328,0.000011410135,0.000011665989,0.00006710592,3.5070737e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053229,0.000014404202,0.00011722431,7.3851606e-7,4.3760784e-7,0.0000021783862,0.000062546766,0.00021748463,0.9920648,0.0003133769,0.0000039121737,0.007149714],"study_design_scores_gemma":[0.00013495747,0.00078190747,0.004000101,0.000022438806,0.000002102565,0.000049695012,0.00005523714,0.0014041535,0.9925113,0.0003054748,0.00069506175,0.00003757315],"about_ca_topic_score_codex":0.0000012387982,"about_ca_topic_score_gemma":0.0000046176997,"teacher_disagreement_score":0.007112141,"about_ca_system_score_codex":0.0000059048757,"about_ca_system_score_gemma":0.000037671525,"threshold_uncertainty_score":0.14166866},"labels":[],"label_agreement":null},{"id":"W2076790897","doi":"10.1523/jneurosci.3734-11.2012","title":"Differential Association of Receptor-Gβγ Complexes with β-Arrestin2 Determines Recycling Bias and Potential for Tolerance of Delta Opioid Receptor Agonists","year":2012,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Desensitization (medicine); Agonist; δ-opioid receptor; Chemistry; Receptor; Internalization; G protein-coupled receptor; Opioid receptor; Pharmacology; Neuroscience; Biophysics; Biology; Biochemistry","score_opus":0.022389809942669484,"score_gpt":0.262045557307371,"score_spread":0.23965574736470152,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076790897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841918,0.00018684295,0.014561014,0.000043401506,0.0008876434,0.00009860385,0.000025071653,0.0000017059855,0.000003912882],"genre_scores_gemma":[0.99319535,0.00020402101,0.0061315014,0.000034768338,0.0003650325,0.0000019662496,0.0000036243607,0.000010873867,0.000052872183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891955,0.000062812396,0.00040214875,0.00014347956,0.00026957464,0.00020242001],"domain_scores_gemma":[0.99862933,0.00004944676,0.000871117,0.000091258466,0.00027123775,0.00008758719],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003932654,0.000107294494,0.00024052108,0.000052481595,0.00008175918,0.000025537416,0.00016989268,0.00006870381,0.0000063521866],"category_scores_gemma":[0.00037920295,0.000083149826,0.00008736956,0.000080653175,0.000081726306,0.000028742847,0.000042675605,0.00007353787,6.726544e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020783195,0.000059747174,0.0111585995,0.00003450848,0.000008488695,2.438163e-7,0.0000582671,0.00012273263,0.98720795,0.000009655322,0.00011180107,0.0010201748],"study_design_scores_gemma":[0.0006163431,0.0009470138,0.009045796,0.0000811157,0.000029927744,0.000031764248,0.000037028094,0.0004088336,0.9871918,0.000016128464,0.0014861581,0.00010808308],"about_ca_topic_score_codex":0.0000037579387,"about_ca_topic_score_gemma":0.0000017569881,"teacher_disagreement_score":0.009003536,"about_ca_system_score_codex":0.0000104679675,"about_ca_system_score_gemma":0.000052153588,"threshold_uncertainty_score":0.33907515},"labels":[],"label_agreement":null},{"id":"W2076914167","doi":"10.1038/sj.bjp.0705002","title":"Regulation of muscarinic receptor function in developing oligodendrocytes by agonist exposure","year":2003,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada","keywords":"Agonist; Internalization; Muscarinic acetylcholine receptor; Homologous desensitization; Receptor; Carbachol; Chemistry; Endocrinology; Muscarinic acetylcholine receptor M3; Cell biology; Internal medicine; Biology; Biochemistry; Medicine","score_opus":0.008800151758793708,"score_gpt":0.2471248064775721,"score_spread":0.2383246547187784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076914167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98843616,0.005238097,0.0052128513,0.00005317526,0.00084220455,0.0000770467,0.000005885073,0.0000021039555,0.00013249836],"genre_scores_gemma":[0.99617374,0.0018644545,0.0015056158,0.00014947019,0.00015111906,0.0000035781022,0.000019415818,0.00001368232,0.0001189261],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893063,0.00019288767,0.0004748621,0.000135576,0.000107067586,0.0001589969],"domain_scores_gemma":[0.9994169,0.00001655723,0.0003243272,0.000035527482,0.00016517095,0.00004152617],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049071334,0.0000844814,0.00019766529,0.00006494635,0.000042805805,0.000013020212,0.000100623634,0.00013773752,0.0008333251],"category_scores_gemma":[0.000059307902,0.0001034493,0.00008212875,0.000096146985,0.000035091998,0.0000111718455,0.000017621212,0.00013732928,0.0000014829807],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010602618,0.00005525447,0.00041886966,0.000016523212,0.000052473213,0.0000072696944,0.000018134697,0.00015234279,0.9881574,0.00007536882,0.006865809,0.0040745386],"study_design_scores_gemma":[0.0013160674,0.00036563922,0.0010585972,0.000045141707,0.00002539275,0.00032274358,0.00006425851,0.000007975174,0.9649974,0.00011318646,0.03157923,0.00010435006],"about_ca_topic_score_codex":0.000011520981,"about_ca_topic_score_gemma":0.000012758594,"teacher_disagreement_score":0.024713421,"about_ca_system_score_codex":0.00003140074,"about_ca_system_score_gemma":0.00012661115,"threshold_uncertainty_score":0.9124325},"labels":[],"label_agreement":null},{"id":"W2076976482","doi":"10.1016/s0893-133x(00)00155-x","title":"Oligomerization of Dopamine and Serotonin Receptors","year":2000,"lang":"en","type":"review","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Medical Research Council Canada; Centre for Addiction and Mental Health","keywords":"G protein-coupled receptor; Receptor; Agonist; Chemistry; Rhodopsin-like receptors; Transmembrane domain; Endogenous agonist; 5-HT receptor; Dopamine receptor; Biophysics; Serotonin; Neuroscience; Cell biology; Biology; Biochemistry; Metabotropic receptor; Dopamine receptor D1","score_opus":0.019975933377633714,"score_gpt":0.32135658695554326,"score_spread":0.30138065357790955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076976482","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0036992063,0.9940955,0.00010292222,0.000007172729,0.0009807998,0.00057297444,0.000025144123,0.000014695137,0.00050158857],"genre_scores_gemma":[0.00012225921,0.99797916,0.00016901057,0.00010426231,0.00035539205,0.00007968694,0.00020750251,0.000078706245,0.0009039911],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99837434,0.00027716198,0.0004986088,0.00053383684,0.000089639565,0.00022639317],"domain_scores_gemma":[0.9993026,0.000026435415,0.00029511444,0.00023360163,0.000049891067,0.000092354065],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00010923935,0.00032765942,0.0007922166,0.00013232342,0.000042452593,0.000009498615,0.00021312009,0.00037317318,0.0006620166],"category_scores_gemma":[0.000020406545,0.00029859852,0.00016927953,0.00022076447,0.00008958743,0.0000024028136,0.000073917516,0.00020138302,0.000015721069],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048698355,0.000041866886,0.0000014637042,0.0012749134,0.000090688474,0.0000031209895,0.0000057599923,0.0000046573978,0.09507707,0.000008412757,0.0004567652,0.9029866],"study_design_scores_gemma":[0.00035630618,0.00035256284,7.5353e-7,0.0002486167,0.00021519602,0.000060833303,0.0000015364502,0.00000398287,0.0042449366,0.0000032878397,0.9942844,0.00022758392],"about_ca_topic_score_codex":0.000002519404,"about_ca_topic_score_gemma":3.7191538e-7,"teacher_disagreement_score":0.99382764,"about_ca_system_score_codex":0.000006496086,"about_ca_system_score_gemma":0.00009491153,"threshold_uncertainty_score":0.9999466},"labels":[],"label_agreement":null},{"id":"W2076993018","doi":"10.1016/j.cellsig.2006.01.012","title":"RGS2 is upregulated by and attenuates the hypertrophic effect of α1-adrenergic activation in cultured ventricular myocytes","year":2006,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba; Western University","funders":"","keywords":"RGS2; Internal medicine; Pressure overload; Endocrinology; Signal transduction; Biology; Muscle hypertrophy; Cell biology; Protein kinase A; G protein; MAPK/ERK pathway; Downregulation and upregulation; Kinase; GTPase-activating protein; Medicine; Gene; Biochemistry","score_opus":0.0027646455602166266,"score_gpt":0.18028565881094394,"score_spread":0.1775210132507273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076993018","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9878201,0.007106422,0.0047532213,0.00004541382,0.00003846814,0.0001957963,0.0000035976354,0.0000073354745,0.000029675624],"genre_scores_gemma":[0.99928045,0.00009880208,0.00015553947,0.000034170913,0.000100262325,0.000013874267,0.00017436015,0.00001995929,0.00012258773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904513,0.0001141491,0.00023663734,0.00027634445,0.00013893639,0.00018881974],"domain_scores_gemma":[0.99963367,0.000032605774,0.000114726594,0.00014680716,0.000044603625,0.000027568489],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002674686,0.00016742478,0.00018894968,0.0000376944,0.00007987354,0.000027322947,0.00012092372,0.0001565927,0.00002079898],"category_scores_gemma":[0.000020148567,0.000116749885,0.000083237224,0.00013682073,0.000045400695,0.000005846548,0.000038503153,0.0000873007,8.5944856e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004641449,0.000021490181,0.0008467227,0.000026200049,0.00002801197,0.000002481253,0.000027717177,0.0019079518,0.9966797,0.000027268505,0.00013768826,0.000248322],"study_design_scores_gemma":[0.00053923664,0.00015585417,0.00006932717,0.0000482092,0.000028482482,0.0000026446903,0.000019214398,0.0024952285,0.9958844,0.00013264154,0.00048557948,0.00013917247],"about_ca_topic_score_codex":0.00010244916,"about_ca_topic_score_gemma":0.00000169187,"teacher_disagreement_score":0.011460374,"about_ca_system_score_codex":0.000010321507,"about_ca_system_score_gemma":0.0000108143495,"threshold_uncertainty_score":0.47609222},"labels":[],"label_agreement":null},{"id":"W2077401555","doi":"10.1074/jbc.m608846200","title":"Dopamine Receptor-interacting Protein 78 Acts as a Molecular Chaperone for Gγ Subunits before Assembly with Gβ","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire de cardiologie et de pneumologie de Québec; McGill University","funders":"","keywords":"Heterotrimeric G protein; G protein; Chaperone (clinical); Protein subunit; Cell biology; G beta-gamma complex; Gq alpha subunit; Endoplasmic reticulum; G protein-coupled receptor; Signal transduction; Receptor; G alpha subunit; Chemistry; Biology; Intracellular; Biochemistry; Gene","score_opus":0.014009378599803496,"score_gpt":0.26264162432628624,"score_spread":0.24863224572648274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077401555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857865,0.00036325617,0.012736866,0.00014470564,0.00009081764,0.0002183105,0.000007820123,0.000010145761,0.0006415634],"genre_scores_gemma":[0.98970854,0.000028593566,0.0089748325,0.00012797474,0.0007142752,0.000011289391,0.000059881226,0.000028905044,0.0003457188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984772,0.000032137785,0.00052418857,0.0003129254,0.00022637648,0.0004271333],"domain_scores_gemma":[0.99857634,0.000047985934,0.00054835714,0.0001832974,0.00040565603,0.00023834764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008375362,0.00026135318,0.0003407696,0.00003138419,0.00008971923,0.000039296912,0.0003063312,0.000361322,0.00012189027],"category_scores_gemma":[0.0006212682,0.0001756408,0.0002165031,0.000101169266,0.000065307875,0.000011150811,0.00007332698,0.00031456587,0.0000023596747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010941959,0.00011155054,0.00014312533,0.00004183145,0.00010280657,0.00005157544,0.000021737736,0.000013988442,0.9960893,0.000034719582,0.000041328698,0.0022538456],"study_design_scores_gemma":[0.0009411199,0.002364515,0.000043545995,0.00013833448,0.000021335916,0.000340082,0.00031437835,0.000009530811,0.9859828,0.00007558014,0.009537394,0.00023142755],"about_ca_topic_score_codex":0.0000017339286,"about_ca_topic_score_gemma":0.0000012242886,"teacher_disagreement_score":0.010106539,"about_ca_system_score_codex":0.000041034033,"about_ca_system_score_gemma":0.000094902694,"threshold_uncertainty_score":0.7162424},"labels":[],"label_agreement":null},{"id":"W2077612184","doi":"10.1007/s11010-013-1832-2","title":"Prevention of RhoA activation and cofilin-mediated actin polymerization mediates the antihypertrophic effect of adenosine receptor agonists in angiotensin II- and endothelin-1-treated cardiomyocytes","year":2013,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canada Research Chairs","keywords":"RHOA; Angiotensin II; Adenosine; Endothelin receptor; Chemistry; Cofilin; Cell biology; Endothelin 1; Angiotensin receptor; Actin; Receptor; Pharmacology; Internal medicine; Endocrinology; Signal transduction; Biology; Medicine; Cell; Cytoskeleton; Biochemistry; Actin cytoskeleton","score_opus":0.002812688705982108,"score_gpt":0.19091450780607455,"score_spread":0.18810181910009244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077612184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942634,0.004564799,0.0007072185,0.00009251894,0.000021935146,0.0003100954,0.000017357985,0.000005968662,0.000016698812],"genre_scores_gemma":[0.9990208,0.0002953545,0.00017853096,0.000017588807,0.00003462396,0.00002104981,0.00036860566,0.000020584412,0.000042827363],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990212,0.00012449798,0.00026147632,0.00030125424,0.00012536599,0.00016623468],"domain_scores_gemma":[0.9994807,0.000036186364,0.00016240063,0.00018579874,0.00007395662,0.000060956805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019825458,0.00018772078,0.00026657173,0.000046771973,0.00005962835,0.000019248531,0.00006811516,0.00020883801,0.000014793751],"category_scores_gemma":[0.00012229125,0.00014625202,0.00006290805,0.00011133396,0.00013855765,0.000008475951,0.00008341021,0.00008053901,2.2298246e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009042592,0.000029038109,0.0030479084,0.00010393248,0.000063668405,0.0000010178732,0.000034368473,0.0000045192455,0.99486244,0.00000659745,0.0000053191357,0.0017507703],"study_design_scores_gemma":[0.00075120013,0.0003279419,0.0003345663,0.000071731796,0.00003792008,0.0000058852124,0.000085707914,0.00018360234,0.99802536,0.000020782412,0.000016496417,0.00013879649],"about_ca_topic_score_codex":0.000104660154,"about_ca_topic_score_gemma":9.4547136e-7,"teacher_disagreement_score":0.004757427,"about_ca_system_score_codex":0.000007028132,"about_ca_system_score_gemma":0.000023656372,"threshold_uncertainty_score":0.5963984},"labels":[],"label_agreement":null},{"id":"W2077859768","doi":"10.1093/intimm/dxn064","title":"DcR3 as a diagnostic parameter and risk factor for systemic lupus erythematosus","year":2008,"lang":"en","type":"article","venue":"International Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Notre-Dame","funders":"Canadian Institutes of Health Research; Ministero dello Sviluppo Economico; Kidney Foundation of Canada; Heart and Stroke Foundation of Canada","keywords":"Systemic risk; Medicine; Systemic lupus; Risk factor; Dermatology; Immunology; Internal medicine; Economics; Financial crisis; Disease","score_opus":0.011522681707775189,"score_gpt":0.24492591069982653,"score_spread":0.23340322899205135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077859768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98810965,0.002156339,0.008446503,0.000083442304,0.0008485444,0.00018727867,0.00006301589,0.000012284271,0.00009292025],"genre_scores_gemma":[0.9950309,0.0026013881,0.0008964363,0.00009585742,0.00016228735,0.000080616686,0.000051736202,0.000017343978,0.0010634816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993211,0.0000362905,0.00017649448,0.00024603494,0.000067145564,0.00015290844],"domain_scores_gemma":[0.9994662,0.00017076178,0.00009613305,0.00013383302,0.000103326165,0.000029786228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000058402235,0.000113213755,0.00012640613,0.00004465272,0.00008273558,0.000014803412,0.00015249086,0.00013930304,0.00011611839],"category_scores_gemma":[0.00054598413,0.000103240505,0.00007499766,0.000016693273,0.00006962312,0.0000045838297,0.000062615436,0.000067698136,0.00002073574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032532454,0.00007117021,0.01781079,0.000014851168,0.0007170095,0.000035077122,0.00033076396,0.000032781096,0.97330976,0.001456029,0.00059605204,0.005300396],"study_design_scores_gemma":[0.005647391,0.0022255597,0.007823806,0.00011336634,0.00010155012,0.030923884,0.0004291487,0.0007982238,0.86627084,0.00489859,0.079831064,0.0009365764],"about_ca_topic_score_codex":0.00002426224,"about_ca_topic_score_gemma":0.0000039285383,"teacher_disagreement_score":0.107038915,"about_ca_system_score_codex":0.000014303165,"about_ca_system_score_gemma":0.000028196255,"threshold_uncertainty_score":0.42100257},"labels":[],"label_agreement":null},{"id":"W2078110334","doi":"10.1007/s00441-005-0102-3","title":"Cell-type-specific pathways of neurotensin endocytosis","year":2005,"lang":"en","type":"article","venue":"Cell and Tissue Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Endocytosis; Neurotensin; Molecular medicine; Cell biology; Cell type; Cell; Human genetics; Biology; Chemistry; Biochemistry; Receptor; Neuropeptide; Cell cycle","score_opus":0.054677449096618945,"score_gpt":0.3040177464812101,"score_spread":0.24934029738459115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078110334","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9827712,0.0108123105,0.00030718613,0.000078385696,0.00006693061,0.00015392734,0.000004836031,0.0000052746764,0.005799903],"genre_scores_gemma":[0.99211365,0.0038744933,0.0012027496,0.000019756992,0.00026470458,0.0000045909837,0.000017083365,0.000018216151,0.002484733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898046,0.00009633521,0.00014464736,0.0002817898,0.00021302454,0.00028376654],"domain_scores_gemma":[0.9994391,0.000025580443,0.000028945648,0.00023641926,0.00016746031,0.00010249981],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035361538,0.00008978611,0.0001174207,0.000063404055,0.000100441255,0.000024409821,0.00013346574,0.000100653,0.00021727332],"category_scores_gemma":[0.000017421205,0.00008164557,0.000032073993,0.000117922544,0.00008102335,0.0000030072763,0.00013002542,0.00013803755,0.000038514983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003803686,0.0000529746,0.000043293756,0.000025022442,0.0000033486522,0.000004367879,0.00006416906,0.000015295584,0.98488563,0.000111751324,0.0031224638,0.01163362],"study_design_scores_gemma":[0.00021135678,0.0003347584,0.00003351295,0.0000054163625,0.0000017425533,0.000004124646,0.00007359425,0.000032739328,0.8028764,0.00005609675,0.19630119,0.000069067406],"about_ca_topic_score_codex":0.000014214549,"about_ca_topic_score_gemma":0.0000018999295,"teacher_disagreement_score":0.19317873,"about_ca_system_score_codex":0.0000056981635,"about_ca_system_score_gemma":0.00003820696,"threshold_uncertainty_score":0.332941},"labels":[],"label_agreement":null},{"id":"W2078425701","doi":"10.1111/j.1600-0854.2009.00890.x","title":"A Single Conserved Leucine Residue on the First Intracellular Loop Regulates ER Export of G Protein‐Coupled Receptors","year":2009,"lang":"en","type":"article","venue":"Traffic","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research","keywords":"Biology; Cell biology; Intracellular; Leucine; Receptor; Residue (chemistry); Biochemistry; Amino acid","score_opus":0.014952434771304722,"score_gpt":0.21040732598895778,"score_spread":0.19545489121765305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078425701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973836,0.00063166104,0.000112398484,0.0011455677,0.00008816245,0.00041322372,0.0000023565076,0.00002475906,0.00019830193],"genre_scores_gemma":[0.9981695,0.000031962532,0.00029703794,0.00023281798,0.00013170592,0.000017881399,0.00003738,0.000021818885,0.0010599233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894196,0.000050246224,0.00030115657,0.0003068004,0.00016727469,0.00023259062],"domain_scores_gemma":[0.9992929,0.000019742241,0.00014124627,0.00041454725,0.0000776053,0.000053922577],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031557647,0.00018264663,0.00019936498,0.000035776582,0.00010245738,0.000020196672,0.00021144167,0.00015630673,0.00026871933],"category_scores_gemma":[0.00008027398,0.00013067534,0.000116355906,0.00011209044,0.000071351446,0.0000030268754,0.000021033364,0.000105699204,0.000010065645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018267767,0.00016206234,0.00001225797,0.000013001942,0.00003133414,0.0000035267258,0.00007715548,0.00080888043,0.99575543,0.00024554785,0.0011625099,0.0015456064],"study_design_scores_gemma":[0.0004247936,0.0011762931,0.000090123904,0.00007566523,0.000015301055,0.000004555957,0.00009165343,0.00044850018,0.99232024,0.00006885409,0.005117463,0.0001665659],"about_ca_topic_score_codex":0.0000068541226,"about_ca_topic_score_gemma":0.000016493948,"teacher_disagreement_score":0.003954953,"about_ca_system_score_codex":0.000012063209,"about_ca_system_score_gemma":0.00004112539,"threshold_uncertainty_score":0.5328786},"labels":[],"label_agreement":null},{"id":"W2078447869","doi":"10.1210/jcem.86.9.7837","title":"Expression and Regulation of Adenylyl Cyclase Isoforms in the Human Adrenal Gland","year":2001,"lang":"en","type":"article","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Medical Research Council; Université Lille 1 - Sciences et Technologies; Université de Sherbrooke","keywords":"Adenylyl cyclase; ADCY10; ADCY9; ADCY6; Gs alpha subunit; ADCY3; cAMP-dependent pathway; Internal medicine; Endocrinology; Biology; Chemistry; Medicine; Stimulation","score_opus":0.03280493497609495,"score_gpt":0.34387985916370634,"score_spread":0.3110749241876114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078447869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960321,0.0023705948,0.00066561776,0.00050182326,0.00020520027,0.00008524746,0.000001340329,0.0000013096636,0.00013675028],"genre_scores_gemma":[0.9954815,0.0032002323,0.00028177255,0.00026684985,0.00068267283,0.0000014462163,0.0000031700329,0.0000073586757,0.00007498128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981404,0.0005338971,0.00086070044,0.00011297904,0.00017036134,0.00018164232],"domain_scores_gemma":[0.9989314,0.00016263041,0.0005470414,0.00022228436,0.00008954966,0.000047111622],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016755962,0.00010275803,0.0003414362,0.000053743563,0.00007627438,0.000008383,0.0003102747,0.0001287132,0.000048549693],"category_scores_gemma":[0.00025783258,0.00005046474,0.00013929294,0.00006238814,0.00019006485,0.000010080044,0.000073782285,0.00035020913,6.3415507e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064029754,0.00013933567,0.007597835,0.0000055758146,0.00006110978,0.000014219602,0.00019891992,0.00008093578,0.98233163,0.001623553,0.0003362358,0.0069703353],"study_design_scores_gemma":[0.0077002756,0.0014920312,0.3870999,0.00010104357,0.00028419148,0.001810499,0.0009186448,0.00008077841,0.54034495,0.015439615,0.044451516,0.00027654503],"about_ca_topic_score_codex":0.0000134524935,"about_ca_topic_score_gemma":0.000011831209,"teacher_disagreement_score":0.44198668,"about_ca_system_score_codex":0.0000015652794,"about_ca_system_score_gemma":0.000035256722,"threshold_uncertainty_score":0.20578924},"labels":[],"label_agreement":null},{"id":"W2078559904","doi":"10.1021/jm9015747","title":"The Amino-Terminus of Angiotensin II Contacts Several Ectodomains of the Angiotensin II Receptor AT<sub>1</sub>","year":2010,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Angiotensin II; Angiotensin receptor; Angiotensin II receptor type 1; Receptor; Renin–angiotensin system; Stereochemistry; Biochemistry; Internal medicine","score_opus":0.00522934887520749,"score_gpt":0.2105129960860561,"score_spread":0.2052836472108486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078559904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99704826,0.0008462781,0.00006657733,0.000919007,0.00082608085,0.00008741347,0.000015697955,0.0000025866766,0.000188126],"genre_scores_gemma":[0.9976346,0.00018535559,0.00042680753,0.00014832329,0.0011259343,0.0000010204803,0.00000844081,0.000023413648,0.0004461288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822825,0.000058361704,0.00069627573,0.00018870196,0.00053970877,0.00028868168],"domain_scores_gemma":[0.997872,0.00006545262,0.00097501883,0.00042820582,0.00049579446,0.00016354474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079584756,0.00021330838,0.00038535084,0.000023344806,0.00029204844,0.000009544568,0.00050199084,0.0003043835,0.00005857067],"category_scores_gemma":[0.000490383,0.00012580231,0.00041113168,0.000101206926,0.00032746914,0.0000069659764,0.00025276726,0.0005068092,5.3726046e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033118195,0.00006571319,0.00022402543,0.000024714122,0.00012726216,0.000014956213,0.0001387287,0.0000128402935,0.9910856,0.000007306368,0.006506925,0.0014607536],"study_design_scores_gemma":[0.0009802807,0.0004351561,0.00069234625,0.00014235418,0.00008881652,0.0007843313,0.00013367532,0.00002233535,0.9854246,0.000040296803,0.011122942,0.00013289326],"about_ca_topic_score_codex":0.000007107434,"about_ca_topic_score_gemma":0.000014042407,"teacher_disagreement_score":0.005661021,"about_ca_system_score_codex":0.0000336052,"about_ca_system_score_gemma":0.00026465082,"threshold_uncertainty_score":0.513007},"labels":[],"label_agreement":null},{"id":"W2078587170","doi":"10.1021/bi3000287","title":"Heterotropic Cooperativity within and between Protomers of an Oligomeric M<sub>2</sub>Muscarinic Receptor","year":2012,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Aging; Canadian Institutes of Health Research","keywords":"Cooperativity; Muscarinic acetylcholine receptor; Cooperative binding; Chemistry; Receptor; Biochemistry; Binding site","score_opus":0.011433861071381854,"score_gpt":0.2438141074515809,"score_spread":0.23238024638019905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078587170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99863046,0.0005448281,0.00028521087,0.0000095826,0.00011772693,0.00026130755,0.00003485455,0.000015661777,0.0001003597],"genre_scores_gemma":[0.99738395,0.000062794104,0.0017094223,0.000030629657,0.0005157714,0.00005351532,0.00016311843,0.000029308703,0.00005151703],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888,0.000062506944,0.00027312888,0.00033917915,0.00014370229,0.00030147439],"domain_scores_gemma":[0.9992117,0.0000094017005,0.00014996635,0.00033826384,0.00006253185,0.00022810769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025748392,0.00020863069,0.00024568947,0.000025274312,0.000069714486,0.00001931074,0.00014747759,0.0002421803,0.000023849705],"category_scores_gemma":[0.000055479897,0.00019918632,0.00007123195,0.00008900799,0.000118169024,0.000012619886,0.000106691754,0.00011397609,0.0000039110137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031997777,0.00006344836,0.0071469434,0.00008099396,0.000050774703,2.1540643e-7,0.00006351124,0.00000198004,0.9903638,0.000007989782,0.000033754328,0.0021546134],"study_design_scores_gemma":[0.00032781524,0.00021532043,0.0014861764,0.000023913706,0.000020040274,0.000007485458,0.00008058015,0.000012975861,0.9973151,0.000005121028,0.00026757424,0.00023788979],"about_ca_topic_score_codex":0.0000071182994,"about_ca_topic_score_gemma":8.398763e-7,"teacher_disagreement_score":0.0069513293,"about_ca_system_score_codex":0.000014969899,"about_ca_system_score_gemma":0.000057472185,"threshold_uncertainty_score":0.81225824},"labels":[],"label_agreement":null},{"id":"W2078617145","doi":"10.1139/y04-086","title":"Differential participation of protein kinase C and Rho kinase in α<sub>1</sub>-adrenoceptor mediated contraction in rat arteries","year":2004,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Phenylephrine; Protein kinase C; Internal medicine; Rho-associated protein kinase; Endocrinology; Contraction (grammar); Stimulation; Biology; Aorta; Vascular smooth muscle; Muscle contraction; Kinase; Medicine; Cell biology; Smooth muscle","score_opus":0.007977624574565221,"score_gpt":0.2402773201701089,"score_spread":0.23229969559554367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078617145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986314,0.0006729911,0.000070862756,0.00016730286,0.00030535294,0.00013617748,0.000012102196,7.6337386e-7,0.0000030554488],"genre_scores_gemma":[0.9994771,0.00022254243,0.000028795737,0.00010621145,0.00012371576,0.000011067615,0.000022214386,0.0000066647945,0.000001675999],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992092,0.00013473115,0.00029395003,0.00013266245,0.000030552317,0.0001988608],"domain_scores_gemma":[0.9995563,0.000018485793,0.0001653535,0.000037508053,0.000060677106,0.00016169855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012841371,0.000098992954,0.00022294765,0.00014697507,0.000038849823,0.0000047161707,0.000049652896,0.00015634258,0.00015624429],"category_scores_gemma":[0.000038399427,0.000094445306,0.000029937704,0.000056621302,0.0001511723,0.000012578409,0.000009779516,0.0001610205,4.620269e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031789634,0.00004116245,0.00060036284,0.00002970567,0.00002399735,0.000026354413,0.0001684089,0.00015033277,0.9977412,0.000038770668,0.000021638838,0.0008401446],"study_design_scores_gemma":[0.0019911826,0.000546941,0.0066057453,0.000026143896,0.000017750828,0.000016622049,0.000051152623,0.000028468967,0.9899593,0.00051115145,0.00016086608,0.00008470107],"about_ca_topic_score_codex":0.00025717294,"about_ca_topic_score_gemma":0.003807977,"teacher_disagreement_score":0.007781951,"about_ca_system_score_codex":0.000026679929,"about_ca_system_score_gemma":0.00026741187,"threshold_uncertainty_score":0.38513678},"labels":[],"label_agreement":null},{"id":"W2078627263","doi":"10.1074/jbc.c600270200","title":"Direct Assessment of CXCR4 Mutant Conformations Reveals Complex Link between Receptor Structure and Gαi Activation","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Receptor; Mutant; Chemistry; Ligand (biochemistry); Biophysics; Chemokine receptor; Protein structure; Biochemistry; Stereochemistry; Cell biology; Biology; Chemokine","score_opus":0.021624302198774443,"score_gpt":0.27793284609238067,"score_spread":0.25630854389360624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078627263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969245,0.00011840584,0.0020559586,0.00013874283,0.000038379654,0.000060755134,0.00008047184,0.0000035736914,0.0005791961],"genre_scores_gemma":[0.99513865,0.00008955216,0.0037687197,0.000030501697,0.0007024211,0.0000010372974,0.00022479135,0.0000060166876,0.000038318136],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990479,0.000042314496,0.00051868317,0.00012751776,0.00013749188,0.0001261149],"domain_scores_gemma":[0.99906206,0.00004222366,0.00054581027,0.000100798294,0.00018352624,0.0000655861],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024925178,0.0001240423,0.000286186,0.000019221716,0.000054323402,0.00001825092,0.000123542,0.00024662807,0.00020634806],"category_scores_gemma":[0.00008514632,0.000087557026,0.000101219455,0.000054100925,0.00007005238,0.000007442419,0.00004680938,0.00015558994,1.476788e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024098537,0.000016693333,0.0049315696,0.000028765533,0.000041823594,4.8238724e-7,0.0000060459774,0.000040946477,0.9938556,0.00002457424,0.00019829374,0.00083109085],"study_design_scores_gemma":[0.00034321542,0.00020934475,0.013964561,0.000035474503,0.000016797956,0.00001719566,0.00003526103,0.000019097835,0.98100567,0.0002919024,0.003955135,0.00010635761],"about_ca_topic_score_codex":0.0000028948632,"about_ca_topic_score_gemma":1.3271185e-7,"teacher_disagreement_score":0.012849959,"about_ca_system_score_codex":0.000019664198,"about_ca_system_score_gemma":0.000049796574,"threshold_uncertainty_score":0.3570472},"labels":[],"label_agreement":null},{"id":"W2078762484","doi":"10.1371/journal.pone.0080532","title":"β-Arrestin Regulation of Myosin Light Chain Phosphorylation Promotes AT1aR-mediated Cell Contraction and Migration","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Heart, Lung, and Blood Institute; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Center for Advancing Translational Sciences; Howard Hughes Medical Institute","keywords":"Arrestin; Myosin light-chain kinase; Cell biology; Phosphorylation; Motility; Dephosphorylation; Myosin; Biology; G protein-coupled receptor; Signal transduction; Chemistry; Phosphatase","score_opus":0.010441474656068404,"score_gpt":0.1815058556460166,"score_spread":0.1710643809899482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078762484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975778,0.00038491204,0.001278853,0.00020849594,0.000027498547,0.00037185036,0.0000036348094,0.0000115943385,0.0001353571],"genre_scores_gemma":[0.9970736,0.000118252836,0.0021798408,0.000021037047,0.00008870785,0.000031340478,0.00019269687,0.0000120350705,0.0002824945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993974,0.000038589325,0.00018083131,0.00016892373,0.0001221828,0.00009205642],"domain_scores_gemma":[0.9995602,0.000013826992,0.00014139268,0.000103659295,0.00014238631,0.00003853317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001156422,0.00008155216,0.000105040075,0.000031081254,0.000042739084,0.000018840146,0.000030462114,0.00012022909,0.000094733994],"category_scores_gemma":[0.000076278084,0.000079245765,0.00002058794,0.000050246632,0.000016088916,0.000011946198,0.000012890365,0.000041366413,0.000008336796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024823248,0.00017444964,0.0014696175,0.000037907943,0.000021708334,4.578306e-8,0.00007902948,0.000009543695,0.99752927,0.000020520878,0.00007114442,0.0005619166],"study_design_scores_gemma":[0.00028261484,0.0001989282,0.0063107936,0.000041700197,0.000024636964,3.2733007e-7,0.00003396878,0.0051177433,0.9876686,0.00016007235,0.00007289999,0.000087750355],"about_ca_topic_score_codex":0.00006387561,"about_ca_topic_score_gemma":0.000015564097,"teacher_disagreement_score":0.009860728,"about_ca_system_score_codex":0.000007459535,"about_ca_system_score_gemma":0.000014128323,"threshold_uncertainty_score":0.32315484},"labels":[],"label_agreement":null},{"id":"W2078901618","doi":"10.1074/jbc.m401796200","title":"Mutation of Tyrosine in the Conserved NPXXY Sequence Leads to Constitutive Phosphorylation and Internalization, but Not Signaling, of the Human B2 Bradykinin Receptor","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"G protein-coupled receptor; Internalization; Receptor; Phosphorylation; Biology; Molecular biology; Transmembrane domain; Mutant; Transmembrane protein; Bradykinin receptor; Cell biology; Biochemistry; Bradykinin; Gene","score_opus":0.028989774110135542,"score_gpt":0.27447478403708037,"score_spread":0.24548500992694483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078901618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99646515,0.00022851926,0.002902452,0.00019857768,0.000043461674,0.00009091148,0.000017408747,0.0000011293688,0.000052419593],"genre_scores_gemma":[0.999111,0.000049005444,0.0005625474,0.00017750288,0.0000654791,0.000002225759,0.000015304251,0.0000035944527,0.000013361641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991456,0.000068439724,0.00044491026,0.00012063318,0.00013562784,0.00008478683],"domain_scores_gemma":[0.999193,0.000034268855,0.00043239567,0.000096895004,0.0002102628,0.000033177297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045068233,0.000092004804,0.00017068906,0.000015559815,0.000040708364,0.000010485276,0.00021255444,0.00013143937,0.000031438474],"category_scores_gemma":[0.00033941443,0.00005299974,0.0000779555,0.0000968553,0.0001936853,0.000005439874,0.000042793446,0.00012407797,1.5021497e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009550572,0.000044623994,0.0044190953,0.00001737495,0.000014765292,0.000001921722,0.00015309194,0.0005758366,0.99436855,0.00021452778,0.00001434161,0.0000803472],"study_design_scores_gemma":[0.0004969358,0.00024588412,0.0015868187,0.00012882875,0.000010363474,0.00004493993,0.00022981649,0.0000058935916,0.9966882,0.00043236447,0.00006585805,0.00006409608],"about_ca_topic_score_codex":0.000022827,"about_ca_topic_score_gemma":0.0000032456342,"teacher_disagreement_score":0.0028322765,"about_ca_system_score_codex":0.000021190277,"about_ca_system_score_gemma":0.00007116544,"threshold_uncertainty_score":0.21612667},"labels":[],"label_agreement":null},{"id":"W2078969479","doi":"10.1002/1098-2396(200011)38:2<177::aid-syn9>3.0.co;2-s","title":"Receptor-mediated internalization of somatostatin in rat cortical and hippocampal neurons","year":2000,"lang":"en","type":"article","venue":"Synapse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Medical Research Council Canada; Deutsche Forschungsgemeinschaft","keywords":"Internalization; Somatostatin receptor; Receptor; Somatostatin; Agonist; Somatostatin receptor 2; Hippocampal formation; Somatostatin receptor 3; Biology; Somatostatin receptor 1; Neuropeptide; Hippocampus; Neuroscience; Cell biology; Endocrinology; Internal medicine; Biochemistry; Medicine","score_opus":0.005308028116847007,"score_gpt":0.2220013755930799,"score_spread":0.2166933474762329,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078969479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984995,0.00017111439,0.0009781582,0.000032261672,0.000056808112,0.00007611219,0.000008011543,0.0000049770333,0.0001730674],"genre_scores_gemma":[0.9991327,0.0002499516,0.00028549015,0.00006989991,0.00002688923,0.0000049090754,0.00007996625,0.000009757271,0.00014045429],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994225,0.00007122044,0.00017891946,0.00015582044,0.000059508464,0.000112029295],"domain_scores_gemma":[0.9998004,0.000014858723,0.000033415137,0.00008835177,0.000018899938,0.000044105116],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008226382,0.00007111046,0.000096935786,0.000026713587,0.000017148832,0.0000074072464,0.000052730767,0.00007524498,0.0006125025],"category_scores_gemma":[0.00006862846,0.000067572764,0.000022602002,0.000055608583,0.000042712865,0.0000028483062,0.000020708429,0.000055875116,0.000008283155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008823944,0.000034070086,0.0048420397,0.000009773037,0.0000070987176,0.0000028098095,0.00009501065,0.000035391644,0.99188817,0.00012861496,0.00015742701,0.0027113708],"study_design_scores_gemma":[0.001015906,0.00046385627,0.0020828622,0.000046334666,0.000007791208,0.00002135334,0.00012554189,0.0011949475,0.99095756,0.00027073707,0.0036191877,0.00019390194],"about_ca_topic_score_codex":0.00001756135,"about_ca_topic_score_gemma":0.000014496738,"teacher_disagreement_score":0.0034617607,"about_ca_system_score_codex":0.000003804999,"about_ca_system_score_gemma":0.000018628165,"threshold_uncertainty_score":0.67064726},"labels":[],"label_agreement":null},{"id":"W2078992165","doi":"10.1210/en.2012-1139","title":"Single-Transmembrane Domain IGF-II/M6P Receptor: Potential Interaction with G Protein and Its Association with Cholesterol-Rich Membrane Domains","year":2012,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; University of Alberta","keywords":"Biology; 5-HT5A receptor; Receptor; Insulin-like growth factor 2 receptor; Enzyme-linked receptor; G protein-coupled receptor; Cell biology; Biochemistry; Insulin-like growth factor 1 receptor; Molecular biology; Growth factor","score_opus":0.007853043826418639,"score_gpt":0.21748347413765395,"score_spread":0.20963043031123532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078992165","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99548644,0.00044550965,0.0023988322,0.00042040416,0.0002836969,0.00039572536,0.000011176482,0.000037395854,0.0005208509],"genre_scores_gemma":[0.9963888,0.000096402895,0.0018658065,0.00013302633,0.00046301482,0.00007575346,0.000099677425,0.000042550953,0.0008349685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984353,0.00015637175,0.00021905104,0.00038878448,0.00019608634,0.0006044044],"domain_scores_gemma":[0.99940246,0.000013862553,0.00018431693,0.00018500345,0.00009186357,0.00012246112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017193148,0.00024807375,0.0002403991,0.00007623865,0.0001951839,0.000033544544,0.0001080711,0.00020128231,0.00013541729],"category_scores_gemma":[0.00002355544,0.0002006647,0.00004333287,0.000087613684,0.000044210155,0.000035286168,0.00006556382,0.0002232753,0.000013842711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046334902,0.00015162793,0.0009480554,0.000027069524,0.00015378957,0.0000048307024,0.00022849724,0.000031778203,0.996776,0.00027274713,0.0000551702,0.0008871113],"study_design_scores_gemma":[0.0017160095,0.0014555232,0.0003517008,0.000030931875,0.00004855041,0.00024039377,0.00023394669,0.000009460036,0.97663754,0.000017023007,0.01897566,0.00028327826],"about_ca_topic_score_codex":0.000015488753,"about_ca_topic_score_gemma":0.000045775116,"teacher_disagreement_score":0.020138452,"about_ca_system_score_codex":0.00006278077,"about_ca_system_score_gemma":0.000030506275,"threshold_uncertainty_score":0.8182869},"labels":[],"label_agreement":null},{"id":"W2079052124","doi":"10.1038/sj.embor.7400052","title":"Roles of G‐protein‐coupled receptor dimerization","year":2004,"lang":"en","type":"review","venue":"EMBO Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":667,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"Canada Research Chairs","keywords":"G protein-coupled receptor; Internalization; Receptor; Function (biology); Cell biology; Biology; Signalling; Rhodopsin-like receptors; Ligand (biochemistry); G protein; Computational biology; Chemistry; Biochemistry; Agonist","score_opus":0.014877818337329485,"score_gpt":0.2759072113108895,"score_spread":0.26102939297356004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079052124","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00059544196,0.99603945,0.001977439,0.000002542481,0.00043839097,0.0006057884,0.000012945885,0.000017096538,0.00031088464],"genre_scores_gemma":[0.0006839678,0.9951556,0.0014785222,0.0000065225836,0.0003378398,0.00009233334,0.0012507602,0.00007856775,0.0009159011],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981264,0.000065475244,0.0008576013,0.00052889605,0.0002180452,0.00020358372],"domain_scores_gemma":[0.9982366,0.000005116326,0.0010064179,0.0005751342,0.00010211329,0.000074647854],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028943876,0.00032522946,0.0008735874,0.00007431652,0.00004743866,0.000018500865,0.00013808215,0.00049177976,0.00026367503],"category_scores_gemma":[0.00011474248,0.0002777687,0.00047464133,0.00013421915,0.000036468635,0.0000027342492,0.00008855267,0.00012702562,0.0000084397425],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015076647,0.00016168585,0.000004396429,0.013792241,0.00055466767,0.000082813145,0.00004454143,0.000056398723,0.24917737,0.00027376675,0.0003173941,0.73551965],"study_design_scores_gemma":[0.00006658505,0.00012137993,1.9664472e-7,0.0049375603,0.00016209974,0.00010118069,0.0000064438364,8.8979255e-7,0.04140113,0.00010019613,0.9527704,0.00033191504],"about_ca_topic_score_codex":0.000014731347,"about_ca_topic_score_gemma":0.0000021968187,"teacher_disagreement_score":0.952453,"about_ca_system_score_codex":0.000027227483,"about_ca_system_score_gemma":0.000413198,"threshold_uncertainty_score":0.99996746},"labels":[],"label_agreement":null},{"id":"W2079065151","doi":"10.1016/j.bmcl.2013.12.033","title":"Design and synthesis of potential dual NK1/NK3 receptor antagonists","year":2013,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Institut de Recherches Servier; Natural Sciences and Engineering Research Council of Canada; Université de Montréal; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Chemistry; Tachykinin receptor; Peptidomimetic; Receptor; Pharmacology; Stereochemistry; Combinatorial chemistry; Biochemistry; Substance P; Medicine; Peptide","score_opus":0.0060252784238391715,"score_gpt":0.19461269920724664,"score_spread":0.18858742078340746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079065151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98681396,0.000496331,0.010693044,0.0015520928,0.00016639242,0.0001935594,0.000009290459,0.00001763767,0.000057697165],"genre_scores_gemma":[0.9947605,0.0001761486,0.0039329086,0.00040983758,0.00052160816,0.000026174119,0.000040767718,0.000035575955,0.000096440555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986302,0.000056661604,0.00032879133,0.0004196484,0.00025287937,0.00031180962],"domain_scores_gemma":[0.9992792,0.000031822365,0.00015746082,0.00027864333,0.000073712625,0.00017914324],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024831676,0.00023758382,0.0002629019,0.000023677325,0.000078075456,0.000026483485,0.00018910764,0.00019500396,0.0010176209],"category_scores_gemma":[0.00012044909,0.00021456784,0.00007736367,0.000075005366,0.00019842465,0.000007521534,0.00009006206,0.00012382994,0.000016225806],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005031314,0.0000362472,0.00005712742,0.00007734036,0.00007295036,0.0000065862487,0.000034610977,0.000005131106,0.9927183,0.0000014722038,0.005612175,0.001327761],"study_design_scores_gemma":[0.0004261069,0.00007089081,0.00010254361,0.000050995193,0.000049848622,0.00008983577,0.00016036956,0.00005949859,0.9980251,0.000010604653,0.00072409824,0.0002301011],"about_ca_topic_score_codex":0.000032795015,"about_ca_topic_score_gemma":1.3336e-7,"teacher_disagreement_score":0.007946583,"about_ca_system_score_codex":0.000019410083,"about_ca_system_score_gemma":0.00006362318,"threshold_uncertainty_score":0.9998956},"labels":[],"label_agreement":null},{"id":"W2079453546","doi":"10.1016/j.neuint.2005.11.014","title":"Muscarinic acetylcholine receptors mediate oligodendrocyte progenitor survival through Src-like tyrosine kinases and PI3K/Akt pathways","year":2006,"lang":"en","type":"article","venue":"Neurochemistry International","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society","keywords":"Proto-oncogene tyrosine-protein kinase Src; Cell biology; Protein kinase B; Tyrosine kinase; Biology; Receptor tyrosine kinase; Chemistry; Signal transduction","score_opus":0.011629265775337043,"score_gpt":0.23367271152814964,"score_spread":0.2220434457528126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079453546","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99374324,0.00052276737,0.0006689383,0.00016959166,0.0016668191,0.00012649222,0.000102054146,0.00004932262,0.0029507591],"genre_scores_gemma":[0.9933294,0.00037253866,0.0009200829,0.00022202528,0.002251429,0.000036732425,0.0009698852,0.00004911969,0.0018488088],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829805,0.000034997767,0.00036489312,0.0006255795,0.0003679501,0.00030853058],"domain_scores_gemma":[0.9992695,0.000024892106,0.00016169768,0.0002701848,0.00017731881,0.00009639448],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000108222484,0.00029312362,0.00019887155,0.00003070027,0.00010731252,0.000084216095,0.0003456997,0.00020729154,0.0002705414],"category_scores_gemma":[0.00008651799,0.0002993841,0.00012774803,0.000073620635,0.00009424626,0.000017475517,0.0002187375,0.00018214471,0.000011640796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009051581,0.00009297034,0.001051157,0.000021668255,0.000046013876,0.000011237611,0.000021226475,0.000049423146,0.99583596,0.00014042977,0.0022577592,0.00038161429],"study_design_scores_gemma":[0.0008144009,0.000088394656,0.0003745642,0.000020293883,0.000020410025,0.00007444052,0.000048821457,0.000094434,0.9466751,0.000121359095,0.05137351,0.0002942331],"about_ca_topic_score_codex":0.000033595206,"about_ca_topic_score_gemma":0.000012675078,"teacher_disagreement_score":0.04916085,"about_ca_system_score_codex":0.000027462775,"about_ca_system_score_gemma":0.00006363476,"threshold_uncertainty_score":0.9999458},"labels":[],"label_agreement":null},{"id":"W2079889598","doi":"10.1073/pnas.0407444102","title":"β-Arrestins bind and decrease cell-surface abundance of the Na <sup>+</sup> /H <sup>+</sup> exchanger NHE5 isoform","year":2005,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute; McGill University; University of British Columbia","funders":"","keywords":"Clathrin; Endocytosis; Cytoplasm; Signal transducing adaptor protein; Gene isoform; Internalization; Cell biology; Biology; Complementary DNA; PDZ domain; Membrane protein; Fusion protein; Vesicle; cDNA library; Clathrin adaptor proteins; Transport protein; Molecular biology; Immunoprecipitation; Cell membrane; Receptor; Signal transduction; Biochemistry; Cell; Membrane; Recombinant DNA; Gene","score_opus":0.019982016315837584,"score_gpt":0.26170994249760243,"score_spread":0.24172792618176486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2079889598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958913,0.00089736766,0.0000114737395,0.0013272958,0.00001471352,0.00020460242,0.000030182122,0.0000044309854,0.0016186754],"genre_scores_gemma":[0.9953842,0.00018823401,0.0033692874,0.00037846362,0.00014622255,0.000006411748,6.002584e-7,0.000008592885,0.0005179748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99831516,0.000012359039,0.00034151803,0.0003389393,0.00076763425,0.00022437789],"domain_scores_gemma":[0.9991967,0.000048455873,0.00039273474,0.000027618215,0.0002585874,0.00007591331],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010148722,0.00015269702,0.00017142596,0.000056938014,0.00026614315,0.00002838522,0.00078988523,0.00015223189,0.00004440085],"category_scores_gemma":[0.00037727636,0.00009558099,0.00010993644,0.00036007346,0.0006838364,0.000047859994,0.0002751372,0.00015007006,9.607047e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027196269,0.000055770775,0.0023869318,0.00006702703,0.000016282764,4.955999e-9,0.0004211042,0.005032003,0.98912686,0.0015201446,0.00072429096,0.00062240526],"study_design_scores_gemma":[0.0002660145,0.00008446149,0.0014620387,0.000087853216,0.000017257707,0.00000801373,0.0004526792,0.011321663,0.98257613,0.0016874166,0.0019110744,0.0001253889],"about_ca_topic_score_codex":0.000012120721,"about_ca_topic_score_gemma":1.9299114e-7,"teacher_disagreement_score":0.0065506995,"about_ca_system_score_codex":0.000017632123,"about_ca_system_score_gemma":0.000080188795,"threshold_uncertainty_score":0.38976794},"labels":[],"label_agreement":null},{"id":"W2080200155","doi":"10.1007/s12079-012-0175-1","title":"Rescue of internalization-defective platelet-activating factor receptor function by EBP50/NHERF1","year":2012,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Internalization; Cell biology; G protein-coupled receptor; PDZ domain; G protein-coupled receptor kinase; Receptor; Platelet-activating factor receptor; Phosphorylation; Platelet-activating factor; Biology; Chemistry; Signal transduction; Biochemistry; Immunology","score_opus":0.011570219541722944,"score_gpt":0.23882803001082661,"score_spread":0.22725781046910368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080200155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9282274,0.0060355393,0.06519518,0.000018954577,0.00013199137,0.00006480167,0.000004744804,0.0000031454804,0.00031820807],"genre_scores_gemma":[0.99517196,0.001034853,0.0034760125,0.000057231595,0.00012957116,0.0000017387405,0.00002556573,0.000017418737,0.00008563751],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989818,0.00021097399,0.00044795827,0.0000824288,0.00015132914,0.00012553521],"domain_scores_gemma":[0.9988544,0.00006586403,0.0005619165,0.00016963719,0.00026388516,0.00008431668],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006097152,0.000107763,0.00017954297,0.000062212835,0.000100158984,0.000024948498,0.00016074022,0.00010960624,0.00014798154],"category_scores_gemma":[0.0000912977,0.00009664838,0.00008890058,0.000068539404,0.00003307511,0.000035350105,0.000061847735,0.00017647592,8.9184357e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001248966,0.000065483604,0.0008510491,0.000017807735,0.000053883112,4.331763e-8,0.00055654044,0.00008658639,0.99517924,0.00008141323,0.00019831158,0.002784721],"study_design_scores_gemma":[0.00044866314,0.00022536202,0.0001334886,0.000078715326,0.000010958524,0.0000066354974,0.0006408113,0.00008317371,0.9875399,0.0000705289,0.0106580015,0.0001037745],"about_ca_topic_score_codex":0.000011802972,"about_ca_topic_score_gemma":8.0402117e-7,"teacher_disagreement_score":0.06694453,"about_ca_system_score_codex":0.000018760833,"about_ca_system_score_gemma":0.000026586129,"threshold_uncertainty_score":0.39412066},"labels":[],"label_agreement":null},{"id":"W2080410583","doi":"10.1016/j.tem.2013.03.003","title":"The fatty acid receptor FFA1/GPR40 a decade later: how much do we know?","year":2013,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Free fatty acid receptor 1; Glucose homeostasis; Fatty acid; Receptor; Secretion; Homeostasis; Insulin; Free fatty acid receptor; Biology; Endocrinology; Biochemistry; Insulin resistance; Polyunsaturated fatty acid; Agonist","score_opus":0.02819738060210052,"score_gpt":0.30461483411490137,"score_spread":0.27641745351280084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080410583","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00050237274,0.9967968,0.000047807618,0.00045734397,0.0013798953,0.00034545653,0.000056938832,0.000027646412,0.00038575687],"genre_scores_gemma":[0.00035505873,0.9919808,0.0008296764,0.000052700663,0.0007423059,0.00044185042,0.00019604142,0.00007975678,0.0053217937],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9968517,0.00053205056,0.0005868509,0.0009313378,0.00015260567,0.0009454973],"domain_scores_gemma":[0.998653,0.0000743727,0.00032971223,0.00072901865,0.000058830658,0.00015505597],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028276103,0.00070329424,0.0013951208,0.00029864724,0.00025858823,0.000120505254,0.00066456164,0.00084903714,0.00026528127],"category_scores_gemma":[0.000072151786,0.0004563757,0.00045628188,0.000270004,0.00027494866,0.0000111044865,0.00041491448,0.00077456364,0.00004826719],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000143574,0.00002930436,0.0000028947136,0.00023291046,0.00023162247,0.000008580145,0.00005228995,1.0641037e-7,0.0029359455,0.0017606096,0.0034449317,0.99128646],"study_design_scores_gemma":[0.000486209,0.000067566114,0.000006746546,0.00037363952,0.00024661806,0.00013179229,0.000070469156,8.906167e-7,0.0069633652,0.00023973969,0.99092746,0.0004855048],"about_ca_topic_score_codex":0.000010593024,"about_ca_topic_score_gemma":0.000025609985,"teacher_disagreement_score":0.9908009,"about_ca_system_score_codex":0.00001997214,"about_ca_system_score_gemma":0.00007900056,"threshold_uncertainty_score":0.9997888},"labels":[],"label_agreement":null},{"id":"W2080452899","doi":"10.1016/s0014-2999(01)00998-0","title":"Nature of the oligomers formed by muscarinic m2 acetylcholine receptors in Sf9 cells","year":2001,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"National Institute of Mental Health; National Institutes of Health; Medical Research Council Canada","keywords":"Digitonin; Sf9; Muscarinic acetylcholine receptor; Immunoprecipitation; Receptor; Biology; Biochemistry; Epitope; Molecular biology; Chaps; Chemistry; Recombinant DNA; Antigen; Spodoptera; Immunology","score_opus":0.0071734503988946825,"score_gpt":0.25653471419547613,"score_spread":0.24936126379658144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080452899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944689,0.0015891829,0.00027008186,0.00045880003,0.0020497642,0.00009622905,0.0000053151493,0.000002004547,0.0010596681],"genre_scores_gemma":[0.99621904,0.001594719,0.00023568171,0.0009798581,0.00044012102,6.8221823e-7,0.0000044598246,0.000026407404,0.000499008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985018,0.000493397,0.00049458595,0.00014763442,0.00013565288,0.00022697312],"domain_scores_gemma":[0.9992672,0.000020354364,0.00042003687,0.00011709087,0.00010338975,0.00007188322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00083680043,0.00013163853,0.00020786439,0.00007221869,0.000039419083,0.000006205399,0.00047638672,0.00009463985,0.00040684204],"category_scores_gemma":[0.0000395002,0.00009456103,0.00017471923,0.00015740517,0.00007645727,0.0000066900557,0.000111504414,0.00048667888,0.000004427808],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018862927,0.000074896045,0.0003271623,0.000006471632,0.00006293608,0.000019832925,0.000080574595,0.00021377747,0.9670196,0.000004153462,0.029692711,0.0023092278],"study_design_scores_gemma":[0.0013666489,0.00030217142,0.00018835445,0.000016252288,0.000028434939,0.00006027052,0.000085035696,0.000011959864,0.7932753,0.00000677657,0.20457464,0.000084174506],"about_ca_topic_score_codex":0.0000017176131,"about_ca_topic_score_gemma":0.0000021744027,"teacher_disagreement_score":0.17488194,"about_ca_system_score_codex":0.000019800531,"about_ca_system_score_gemma":0.00005965115,"threshold_uncertainty_score":0.4454635},"labels":[],"label_agreement":null},{"id":"W2080599116","doi":"10.1002/psc.875","title":"Temperature‐dependent variations of ligand‐receptor contact points in hAT<sub>1</sub>","year":2007,"lang":"en","type":"article","venue":"Journal of Peptide Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Ligand (biochemistry); Chemistry; Receptor; Labelling; Benzophenone; Mutagenesis; Stereochemistry; Photoaffinity labeling; Biophysics; Mutant; Biochemistry; Biology; Photochemistry","score_opus":0.006794604504308313,"score_gpt":0.24610861653427726,"score_spread":0.23931401202996894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080599116","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945517,0.00019845556,0.004436477,0.00007341714,0.00045994652,0.000068611516,0.000004174627,0.0000014649532,0.00020574655],"genre_scores_gemma":[0.9965979,0.00011102121,0.0029582754,0.00009205186,0.00019443287,5.6512954e-7,0.00000156996,0.00000705647,0.000037161837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860007,0.000030643296,0.000504182,0.00017773168,0.00043669474,0.00025069554],"domain_scores_gemma":[0.99895763,0.000026711878,0.00036442204,0.00014750214,0.00037113487,0.00013262159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0026365772,0.00009819761,0.00017760116,0.00022109684,0.00007501649,0.000037762242,0.00033718772,0.000086855354,0.000021622602],"category_scores_gemma":[0.00035213443,0.00008179172,0.000095964104,0.00031840027,0.00008546349,0.000029246605,0.000058028956,0.00016639564,0.0000031597115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005782052,0.00005926864,0.0010075399,0.0000046113037,0.000009232148,0.000005746847,0.00012167349,0.000091597554,0.99739015,0.00024139245,0.00010342912,0.000907522],"study_design_scores_gemma":[0.0004332922,0.00035199718,0.0054717734,0.000059957256,0.000006164832,0.00003639825,0.00019208516,0.000017092061,0.9930028,0.00014065202,0.00019689293,0.000090909445],"about_ca_topic_score_codex":0.000007971993,"about_ca_topic_score_gemma":0.000031021074,"teacher_disagreement_score":0.0044642333,"about_ca_system_score_codex":0.000048733913,"about_ca_system_score_gemma":0.00032916837,"threshold_uncertainty_score":0.33353692},"labels":[],"label_agreement":null},{"id":"W2080832714","doi":"10.1038/nsb950","title":"Opioid receptor random mutagenesis reveals a mechanism for G protein–coupled receptor activation","year":2003,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"AstraZeneca (Canada)","funders":"National Institute on Drug Abuse; National Institutes of Health; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale","keywords":"G protein-coupled receptor; Rhodopsin; Mutagenesis; Receptor; G protein; Opioid receptor; 5-HT5A receptor; Point mutation; Chemistry; 5-HT7 receptor; Biophysics; Cell biology; Mutant; Biology; Biochemistry; Opioid; Gene","score_opus":0.005147854237649091,"score_gpt":0.2651194816219914,"score_spread":0.2599716273843423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080832714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8673183,0.00078737264,0.12857717,0.00027492808,0.0010068769,0.0017972239,0.00009092856,0.0000488121,0.00009837976],"genre_scores_gemma":[0.9549507,0.00004320322,0.04144482,0.0011464598,0.00040227233,0.00038088288,0.001078445,0.00008601186,0.00046724256],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99740595,0.00034006362,0.00046834716,0.0009560674,0.0001879032,0.000641692],"domain_scores_gemma":[0.9985786,0.000027852304,0.00029281888,0.0005082928,0.00043067933,0.00016172646],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0004194398,0.00048550285,0.00048614873,0.00011283743,0.00025811893,0.0000475989,0.00035946505,0.0013961443,0.00032010433],"category_scores_gemma":[0.0010484147,0.00041714477,0.0003806337,0.000198669,0.00007633946,0.00001128167,0.00007082237,0.0003875423,0.000008535688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043900593,0.000013724382,0.000014339698,0.000034940917,0.00014872594,6.8746243e-7,0.000021732556,0.000012261284,0.9365355,0.061745297,0.00029242015,0.0007413998],"study_design_scores_gemma":[0.0023724157,0.00057999516,0.000007832592,0.0000266348,0.00003594713,0.000011149646,0.000040157676,0.000063266634,0.9616282,0.023892976,0.010830104,0.00051132176],"about_ca_topic_score_codex":0.000010545502,"about_ca_topic_score_gemma":0.0000024494475,"teacher_disagreement_score":0.087632366,"about_ca_system_score_codex":0.000051818166,"about_ca_system_score_gemma":0.0001227565,"threshold_uncertainty_score":0.9999003},"labels":[],"label_agreement":null},{"id":"W2080866754","doi":"10.1016/j.bpj.2008.12.3580","title":"The Effect of Detergent on Human Mu-opioid Receptor (hMOR) Localization as a Function of Pretreatment with Agonist and Antagonist","year":2009,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina","funders":"","keywords":"Receptor; G protein-coupled receptor; G protein; Chemistry; Lipid raft; Etorphine; Adenylyl cyclase; Opioid receptor; Pertussis toxin; Membrane; Membrane protein; Cell membrane; Opioid; Cell biology; (+)-Naloxone; Biochemistry; Biology","score_opus":0.005437090005424511,"score_gpt":0.24140624036077737,"score_spread":0.23596915035535287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080866754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996893,0.00009822708,0.0026860186,0.00003655895,0.00008161386,0.00012549428,0.0000031807965,0.0000025511185,0.000073385425],"genre_scores_gemma":[0.99952203,0.00012478973,0.0000705306,0.000027984343,0.00018731244,0.0000031158145,0.000015981912,0.000007957726,0.000040317194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999334,0.00007841843,0.0001766576,0.00013399996,0.0001645588,0.00011238709],"domain_scores_gemma":[0.9995917,0.000013376363,0.00016385982,0.00011392464,0.000054527827,0.00006258386],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012643356,0.00011439518,0.00013772272,0.00001756696,0.00021253392,0.00003142614,0.000063673644,0.00005368639,0.00001029525],"category_scores_gemma":[0.000012646471,0.000063271356,0.000076090866,0.000045010584,0.00007046467,0.0000034046184,0.000011983118,0.000067060464,9.67025e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000911084,0.000071349445,0.0002683028,0.000009072686,0.000055476277,0.0000010300661,0.000015838756,0.000050966915,0.9892686,0.00027876903,0.00006094177,0.009008546],"study_design_scores_gemma":[0.00066048827,0.017944548,0.001041949,0.000043551914,0.00004504272,0.000011841658,0.000017727381,0.0000517229,0.97932166,0.00007660345,0.0007124138,0.000072474446],"about_ca_topic_score_codex":0.000004405249,"about_ca_topic_score_gemma":0.0000011519481,"teacher_disagreement_score":0.0178732,"about_ca_system_score_codex":0.000014016048,"about_ca_system_score_gemma":0.000018656418,"threshold_uncertainty_score":0.2580131},"labels":[],"label_agreement":null},{"id":"W2080985839","doi":"10.1385/cbb:45:1:85","title":"Detecting and Imaging Protein-Protein Interactions During G Protein-Mediated Signal Transduction In Vivo and In Situ by Using Fluorescence-Based Techniques","year":2006,"lang":"en","type":"review","venue":"Cell Biochemistry and Biophysics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Heterotrimeric G protein; Bimolecular fluorescence complementation; Förster resonance energy transfer; G protein-coupled receptor; G protein; Signal transduction; Cell biology; Effector; Biology; 14-3-3 protein; Protein–protein interaction; Biophysics; Chemistry; Biochemistry; Fluorescence; Gene; Phosphorylation","score_opus":0.008781920664711182,"score_gpt":0.24060662308861847,"score_spread":0.2318247024239073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080985839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.712135,0.2863316,0.0004405755,0.0000054005845,0.000019318657,0.00095189415,0.000059658152,0.000023760616,0.000032748903],"genre_scores_gemma":[0.8863312,0.110289544,0.0021533947,0.000007187522,0.00032354507,0.00030828168,0.00035269122,0.000097495955,0.0001366758],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981663,0.000087012806,0.00049904577,0.00078771944,0.0001154343,0.00034444418],"domain_scores_gemma":[0.9993897,0.000013084208,0.00028040583,0.0001888248,0.00003992119,0.00008805092],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016792519,0.00049254746,0.0005658856,0.00011126598,0.00014158372,0.0000956247,0.00010909703,0.00037702807,0.000008231552],"category_scores_gemma":[0.000015518668,0.0004940438,0.00011025979,0.00022709473,0.00012815809,0.000018828416,0.0000801588,0.0004497315,1.5627047e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003026076,0.000064911444,0.0000060006137,0.005309253,0.00001016255,0.00000854968,0.000008069091,0.000001032446,0.9567035,2.1653464e-7,0.0000016771452,0.037856374],"study_design_scores_gemma":[0.00031811572,0.00004140496,2.954628e-7,0.0050593438,0.000046732108,0.000020419218,0.000036075573,0.000104091734,0.9914846,0.000015382995,0.0023498484,0.0005237023],"about_ca_topic_score_codex":0.00006446162,"about_ca_topic_score_gemma":0.0000054752227,"teacher_disagreement_score":0.17604207,"about_ca_system_score_codex":0.000068523266,"about_ca_system_score_gemma":0.000108380824,"threshold_uncertainty_score":0.9997511},"labels":[],"label_agreement":null},{"id":"W2081392226","doi":"10.1523/jneurosci.2050-12.2012","title":"Stoichiometry of the Human Glycine Receptor Revealed by Direct Subunit Counting","year":2012,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Institut Universitaire en Santé Mentale de Québec","funders":"National Center for Research Resources; National Institute of General Medical Sciences","keywords":"Homomeric; Xenopus; Glycine receptor; Stoichiometry; Protein subunit; Photobleaching; Glycine; Receptor; Biophysics; Chemistry; Biology; Biochemistry; Amino acid; Physics; Fluorescence","score_opus":0.016031643240638015,"score_gpt":0.263911834225316,"score_spread":0.24788019098467798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081392226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997676,0.00066453655,0.0003903489,0.00007685584,0.0008795498,0.000044260236,0.0000058683877,0.0000015166185,0.00026107492],"genre_scores_gemma":[0.99869156,0.000086729,0.00019881061,0.00023703818,0.00025992634,4.3493927e-7,6.939971e-7,0.000009121403,0.00051568955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990139,0.00008772379,0.0003026364,0.00010176156,0.00029974955,0.00019425483],"domain_scores_gemma":[0.99915874,0.000015718146,0.00046225885,0.00016822838,0.00011551802,0.000079528516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00075329636,0.00008204313,0.00014060241,0.000048643367,0.00013212045,0.000017384524,0.0003945944,0.000046108675,0.000022340342],"category_scores_gemma":[0.0003242299,0.000053558582,0.000104547864,0.00026179274,0.00008971133,0.000016117008,0.00008423456,0.00012731526,5.005636e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009202815,0.000046792742,0.010280293,0.0000059235736,0.000003051775,2.2967488e-7,0.000024882544,0.000009714517,0.98757505,0.000015181839,0.0018583172,0.00017137827],"study_design_scores_gemma":[0.00018432806,0.00023774356,0.008626024,0.000027880573,0.000010516326,0.000034716242,0.00003603122,0.000007604619,0.96113294,0.0000066595703,0.029625515,0.00007005268],"about_ca_topic_score_codex":0.0000029920827,"about_ca_topic_score_gemma":3.2953216e-7,"teacher_disagreement_score":0.027767198,"about_ca_system_score_codex":0.000008955896,"about_ca_system_score_gemma":0.00003596105,"threshold_uncertainty_score":0.21840556},"labels":[],"label_agreement":null},{"id":"W2081774969","doi":"10.1016/s0197-0186(02)00073-6","title":"Mechanisms of metabotropic glutamate receptor desensitization: role in the patterning of effector enzyme activation","year":2002,"lang":"en","type":"review","venue":"Neurochemistry International","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Metabotropic glutamate receptor; G protein-coupled receptor; G protein-coupled receptor kinase; Metabotropic glutamate receptor 7; Cell biology; Metabotropic glutamate receptor 6; Biology; Metabotropic glutamate receptor 2; Homologous desensitization; Metabotropic glutamate receptor 1; G protein; Class C GPCR; Metabotropic glutamate receptor 5; Protein kinase C; Neuroscience; Chemistry; Glutamate receptor; Signal transduction; Receptor; Desensitization (medicine); Biochemistry","score_opus":0.018373059439586982,"score_gpt":0.2701489886738134,"score_spread":0.25177592923422637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081774969","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.035699334,0.93684494,0.021290418,0.0001388489,0.0022251173,0.0015835128,0.00063700555,0.0000364273,0.0015443716],"genre_scores_gemma":[0.1348199,0.86036706,0.0009544356,0.00010359641,0.00072278734,0.00013937261,0.0024021307,0.000093552255,0.00039719863],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984017,0.000160314,0.0005855149,0.00035211982,0.00035396105,0.00014635942],"domain_scores_gemma":[0.9988673,0.00007331024,0.00059564516,0.0003035626,0.00013351181,0.000026715303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018687497,0.00026320753,0.0005006967,0.000079099766,0.000025725967,0.000021477326,0.0005256389,0.0002658239,0.00031831407],"category_scores_gemma":[0.00014019081,0.00021172277,0.0002961092,0.0001248118,0.000031515432,0.0000066984235,0.00009236068,0.00021823011,0.000006516138],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017106646,0.00008840724,0.0000044703966,0.0015659591,0.000121863144,0.0000024951858,0.000033165437,0.00004512475,0.9625373,0.00009934741,0.00019164108,0.035293113],"study_design_scores_gemma":[0.00027423276,0.00010387317,0.0000044249296,0.0018568141,0.000101032034,0.000028103808,0.000036874982,0.000092398644,0.7099037,0.000051900268,0.28729904,0.00024757683],"about_ca_topic_score_codex":0.0000051950024,"about_ca_topic_score_gemma":5.1922444e-7,"teacher_disagreement_score":0.28710738,"about_ca_system_score_codex":0.000024463889,"about_ca_system_score_gemma":0.000052816955,"threshold_uncertainty_score":0.8633804},"labels":[],"label_agreement":null},{"id":"W2081833468","doi":"10.1126/scisignal.2002522","title":"Differential β-Arrestin–Dependent Conformational Signaling and Cellular Responses Revealed by Angiotensin Analogs","year":2012,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":165,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; McGill University; Université de Sherbrooke; Université de Montréal; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Arrestin; Angiotensin II; Cell biology; Chemistry; Signal transduction; Renin–angiotensin system; Biophysics; Biology; Biochemistry; Receptor; Endocrinology; G protein-coupled receptor","score_opus":0.01148956477377671,"score_gpt":0.2428143493009762,"score_spread":0.23132478452719948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081833468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9740246,0.0011198055,0.024133772,0.000054894983,0.00036815676,0.00014865282,0.000022700606,0.000020203961,0.000107228676],"genre_scores_gemma":[0.9970618,0.000021713822,0.0020892129,0.00016431155,0.00037682828,0.000007420773,0.00006142597,0.000017222497,0.00020010454],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980668,0.00008952279,0.0003226255,0.00040185504,0.00050816487,0.00061103853],"domain_scores_gemma":[0.9991489,0.00004184712,0.00014641389,0.00021144256,0.00015687998,0.00029451048],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012694155,0.00020544644,0.00017745994,0.00012762017,0.0005161478,0.0001437689,0.00026460414,0.000117545635,0.00019841977],"category_scores_gemma":[0.00020775512,0.00018850385,0.000069521004,0.00020829249,0.00029747243,0.000053589563,0.0001629024,0.00012736199,0.0000093837325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048024707,0.000025449512,0.002064641,0.0000073690708,0.000013233453,0.0000010664486,0.00018860651,0.000073096846,0.99671406,0.00019089464,0.00013109163,0.0005424448],"study_design_scores_gemma":[0.00030843384,0.00009171232,0.00029335462,0.000027387816,0.000019263369,0.000021411537,0.0003029879,0.0004739759,0.99744856,0.000082737606,0.0006610686,0.0002691263],"about_ca_topic_score_codex":0.000016918215,"about_ca_topic_score_gemma":6.4712947e-7,"teacher_disagreement_score":0.023037175,"about_ca_system_score_codex":0.000026497404,"about_ca_system_score_gemma":0.00012580496,"threshold_uncertainty_score":0.7686964},"labels":[],"label_agreement":null},{"id":"W2082448040","doi":"10.1016/j.bmcl.2006.01.084","title":"Ketopiperazine-based renin inhibitors: Optimization of the “C” ring","year":2006,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NAEJA-RGM Pharmaceuticals (Canada)","funders":"","keywords":"Chemistry; Steric effects; Renin–angiotensin system; Stereochemistry; Enzyme inhibitor; Ring (chemistry); Enzyme; Renin inhibitor; Inhibitory postsynaptic potential; CYP3A4; Side chain; Reduction (mathematics); Biological activity; Pharmacology; In vitro; Biochemistry; Internal medicine; Polymer; Organic chemistry; Blood pressure","score_opus":0.004173212106342079,"score_gpt":0.18687605310137348,"score_spread":0.1827028409950314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082448040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98208994,0.00029898717,0.015530474,0.0014252448,0.00021510568,0.00010073059,0.0000060639745,0.00001560859,0.0003178695],"genre_scores_gemma":[0.99739134,0.000006994728,0.001132751,0.0004569484,0.00075982756,0.0000059299864,0.000076122546,0.000023797753,0.00014629323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898547,0.00002853929,0.00028246493,0.0002636585,0.0002449246,0.0001949417],"domain_scores_gemma":[0.9994214,0.000009879648,0.00015816695,0.00031126654,0.000055000703,0.000044273187],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000154121,0.00015791846,0.00013772758,0.000014873539,0.00007516871,0.000011374395,0.0002377019,0.0001265669,0.00017450254],"category_scores_gemma":[0.000059918373,0.00012156393,0.0001057212,0.00013485336,0.000104475555,0.0000028338477,0.00005325169,0.00010884211,0.0000010992303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019676878,0.000023130682,0.0007837675,0.000035761754,0.000011626224,0.0000014650129,0.000007807041,0.0035882064,0.9938219,0.000003777779,0.0016340504,0.00006880203],"study_design_scores_gemma":[0.0004959142,0.000018898003,0.0002044827,0.00006950629,0.000024013416,0.000009672902,0.000021708855,0.0004770044,0.9969719,0.000004387387,0.0015679137,0.0001345877],"about_ca_topic_score_codex":0.00004300498,"about_ca_topic_score_gemma":0.0000021210878,"teacher_disagreement_score":0.015301419,"about_ca_system_score_codex":0.000028895507,"about_ca_system_score_gemma":0.000071764734,"threshold_uncertainty_score":0.4957233},"labels":[],"label_agreement":null},{"id":"W2082581711","doi":"10.1016/j.peptides.2005.03.051","title":"Angiotensin II induced increase in frequency of cytosolic and nuclear calcium waves of heart cells via activation of AT1 and AT2 receptors","year":2005,"lang":"en","type":"article","venue":"Peptides","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Angiotensin II; Internal medicine; Endocrinology; Angiotensin II receptor type 1; Cytosol; Receptor; Protein kinase C; Activator (genetics); Chemistry; Biology; Signal transduction; Medicine; Biochemistry","score_opus":0.011557435693316619,"score_gpt":0.23237113331638273,"score_spread":0.2208136976230661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082581711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9995192,0.00018113051,0.000046817535,0.00006109722,0.000021405262,0.00008900786,0.000005713542,0.0000023721404,0.00007321781],"genre_scores_gemma":[0.99489254,0.00008262138,0.0049055545,0.000036535017,0.000045878198,0.0000012081862,0.000008875581,0.000011737629,0.000015074662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940246,0.000034947,0.00023514865,0.00015778422,0.00006983685,0.00009982624],"domain_scores_gemma":[0.9996661,0.000011467349,0.00011316171,0.00011197455,0.000057048368,0.00004027524],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013831859,0.00008837163,0.00018592557,0.00006159851,0.000024148056,0.0000030914337,0.0000420531,0.00011148084,0.000023637389],"category_scores_gemma":[0.000039939,0.000085122374,0.00003711875,0.00006382647,0.00006194375,0.000008796774,0.000055644152,0.000045993256,2.3356647e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040413688,0.000045029767,0.0014066441,0.000027759885,0.000013506931,1.0506163e-7,0.0003260417,0.000008742123,0.9964793,0.000049912564,0.000040851024,0.001561693],"study_design_scores_gemma":[0.0002715319,0.0002607441,0.0036141898,0.00005018434,0.000007290004,0.0000017827327,0.00012599448,0.0000673872,0.99523365,0.00010213219,0.00018439717,0.000080725964],"about_ca_topic_score_codex":0.00065697037,"about_ca_topic_score_gemma":0.000035333956,"teacher_disagreement_score":0.004858737,"about_ca_system_score_codex":0.000006043702,"about_ca_system_score_gemma":0.00001883859,"threshold_uncertainty_score":0.34711894},"labels":[],"label_agreement":null},{"id":"W2082607173","doi":"10.3389/fnmol.2011.00038","title":"Beyond cAMP: the regulation of Akt and GSK3 by dopamine receptors","year":2011,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression; Compagnia di San Paolo","keywords":"Neuroscience; Dopamine; Receptor; Protein kinase B; Signalling; D1-like receptor; Dopamine receptor D2; Cell biology; Biology; Signal transduction; Chemistry; Medicine; Internal medicine; Dopamine receptor D1","score_opus":0.0070126872773108966,"score_gpt":0.19865570132139698,"score_spread":0.1916430140440861,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082607173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9007021,0.0011553946,0.09658085,0.000046680496,0.0007973071,0.00019436769,0.0000094912675,0.0000055755017,0.0005082196],"genre_scores_gemma":[0.9931569,0.00015341604,0.0062134583,0.00024442383,0.000014284357,0.000008004913,0.000012560227,0.000012546896,0.00018437223],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991101,0.00007590431,0.00017006605,0.00031674388,0.00015207831,0.0001751121],"domain_scores_gemma":[0.9996005,0.0000032781227,0.00008559744,0.00024089897,0.000024239032,0.00004546951],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023957784,0.00010386566,0.00010447268,0.00004542166,0.000059822596,0.00001305024,0.00024237011,0.00006742749,0.000011309452],"category_scores_gemma":[0.00006866487,0.000082946695,0.000028973089,0.00016564512,0.00023646762,0.0000074109894,0.00008341521,0.00006916907,2.571625e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001846064,0.000025068588,0.0016238921,0.000004220034,0.0000020051546,0.0000011685513,0.00007287974,0.00002632803,0.99497885,0.00015385349,0.0016545736,0.0014386799],"study_design_scores_gemma":[0.00016268545,0.00021250396,0.00097068684,0.0000055325936,0.0000053996005,0.0000055076057,0.00008641214,0.0004145119,0.99234366,0.00059145,0.0050950064,0.00010664196],"about_ca_topic_score_codex":0.000015808535,"about_ca_topic_score_gemma":0.0000016452866,"teacher_disagreement_score":0.09245482,"about_ca_system_score_codex":0.0000054209627,"about_ca_system_score_gemma":0.00001986321,"threshold_uncertainty_score":0.33824682},"labels":[],"label_agreement":null},{"id":"W2082662353","doi":"10.1152/ajpcell.00016.2012","title":"Automated region of interest analysis of dynamic Ca<sup>2+</sup> signals in image sequences","year":2012,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Region of interest; Algorithm; Artificial intelligence; Noise (video); Computer science; SIGNAL (programming language); Amplitude; Computer vision; Physics; Pattern recognition (psychology); Image (mathematics); Optics","score_opus":0.012465331037445933,"score_gpt":0.2674489589365498,"score_spread":0.25498362789910384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082662353","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987912,0.00052265904,0.00040269323,0.000034854773,0.00010163459,0.0000840363,0.000021348913,0.0000068548497,0.000034676297],"genre_scores_gemma":[0.9979627,0.00033642238,0.001373163,0.00010627389,0.000113103815,0.0000041589096,0.00006961179,0.000021823469,0.000012754761],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99766445,0.00056308036,0.000940411,0.00029407485,0.00010776383,0.0004302173],"domain_scores_gemma":[0.997639,0.000106996915,0.0015253151,0.00034165184,0.00026839782,0.00011866436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042138816,0.0002555227,0.0011786434,0.00045964506,0.000029075374,0.0000034830612,0.00044114387,0.00015902787,0.000110799156],"category_scores_gemma":[0.00007418424,0.00021115612,0.00048595434,0.00067987584,0.00065806264,0.000022977547,0.00011236477,0.00023007985,0.000002849277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039523386,0.00028996772,0.0003322707,0.000033524462,0.00063851854,0.0000022725471,0.00036852903,0.017376311,0.9800416,0.000012224588,0.0001345546,0.0003749577],"study_design_scores_gemma":[0.0009862,0.0038804633,0.01773455,0.000074626754,0.00047601695,0.00003876307,0.003111217,0.016731977,0.9560918,0.00034820894,0.0001127297,0.0004134549],"about_ca_topic_score_codex":0.00014909609,"about_ca_topic_score_gemma":0.000009502995,"teacher_disagreement_score":0.023949843,"about_ca_system_score_codex":0.0000315387,"about_ca_system_score_gemma":0.00009696622,"threshold_uncertainty_score":0.8610696},"labels":[],"label_agreement":null},{"id":"W2082830168","doi":"10.1007/s002130000671","title":"Infralimbic muscarinic M1 receptors modulate anxiety-like behaviour and spontaneous working memory in mice","year":2001,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; University of Ottawa","keywords":"Anxiogenic; Pirenzepine; Elevated plus maze; Muscarinic acetylcholine receptor; Anxiolytic; Psychology; Muscarinic antagonist; Endocrinology; Working memory; Antagonist; Scopolamine Hydrobromide; Agonist; Infralimbic cortex; Spontaneous alternation; Internal medicine; Muscarinic acetylcholine receptor M1; Muscarinic agonist; Acetylcholine; Pharmacology; Prefrontal cortex; Neuroscience; Medicine; Receptor; Anxiety; Hippocampus; Psychiatry; Cognition","score_opus":0.010173394978047767,"score_gpt":0.26560217839015393,"score_spread":0.2554287834121062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082830168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942768,0.0017230845,0.0001586175,0.00016495047,0.0019913977,0.00028097004,0.0000025883044,0.00002372012,0.0013778546],"genre_scores_gemma":[0.99211204,0.0038841777,0.0005175243,0.0012328055,0.00025814434,0.000049792885,0.000031028492,0.00002876716,0.0018857346],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984376,0.00014265094,0.00032585298,0.0005712796,0.00008798116,0.00043464196],"domain_scores_gemma":[0.99954194,0.000022856084,0.00009249237,0.0001903064,0.00003615545,0.00011623393],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029346874,0.0002312793,0.00023895902,0.00013681063,0.0000823159,0.000021675418,0.00020883515,0.0002984774,0.00036105185],"category_scores_gemma":[0.000013229565,0.00025054658,0.00008007036,0.00018996428,0.000060461913,0.0000054910956,0.000109665125,0.00024570958,0.0000094640345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006286675,0.00012508812,0.017963933,0.0000136624085,0.000058158184,0.0001763406,0.00013832493,0.0002641967,0.9551547,0.000013293175,0.0015755591,0.023888038],"study_design_scores_gemma":[0.026554001,0.0023966474,0.040984463,0.0002953937,0.0005261772,0.0060528195,0.0015170216,0.0028536338,0.5264835,0.0014752052,0.38675234,0.004108805],"about_ca_topic_score_codex":0.000068317,"about_ca_topic_score_gemma":0.00010224419,"teacher_disagreement_score":0.42867124,"about_ca_system_score_codex":0.000030237883,"about_ca_system_score_gemma":0.000037784925,"threshold_uncertainty_score":0.9999947},"labels":[],"label_agreement":null},{"id":"W2082908197","doi":"10.1006/abio.2000.4698","title":"A Reporter Gene Assay for High-Throughput Screening of G-Protein-Coupled Receptors Stably or Transiently Expressed in HEK293 EBNA Cells Grown in Suspension Culture","year":2000,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":111,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada); Biotechnology Research Institute","funders":"","keywords":"HEK 293 cells; Molecular biology; Biology; Forskolin; Reporter gene; Transfection; G protein-coupled receptor; Receptor; Ionomycin; Cell culture; Signal transduction; Cell biology; Biochemistry; Gene expression; Intracellular; Gene","score_opus":0.012380395851367812,"score_gpt":0.2469402600033727,"score_spread":0.23455986415200492,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082908197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99398214,0.00021900567,0.004981297,0.000087127264,0.000049059807,0.00044427678,0.00005392242,0.000011602715,0.00017158629],"genre_scores_gemma":[0.98819536,0.00012924112,0.008466291,0.0000944278,0.00015107692,0.000055863136,0.00038754477,0.00003825085,0.0024819172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976701,0.000059843915,0.0007637201,0.0007696734,0.00026057364,0.00047609443],"domain_scores_gemma":[0.999116,0.00003418673,0.00015009733,0.00044512583,0.00011678087,0.00013782801],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005243479,0.00030508035,0.00048407743,0.000056580546,0.00004604845,0.000025589954,0.00023953736,0.0005038216,0.0007706652],"category_scores_gemma":[0.00014590839,0.00026001947,0.00020498113,0.00027085643,0.000088063134,0.000011075963,0.00004487363,0.0001838863,0.000002020658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009848917,0.00017258158,0.00007449392,0.00009305828,0.00004853966,0.000027169277,0.000058604768,0.00022342292,0.99646384,0.000011480688,0.0004533443,0.0013885847],"study_design_scores_gemma":[0.001670033,0.00028349584,0.000025950922,0.00014322298,0.0000305099,0.0000070672627,0.00014345393,0.0014388487,0.99446297,0.00008969092,0.0013655066,0.00033927202],"about_ca_topic_score_codex":0.00012055975,"about_ca_topic_score_gemma":0.00003569755,"teacher_disagreement_score":0.005786735,"about_ca_system_score_codex":0.00003567379,"about_ca_system_score_gemma":0.00010384115,"threshold_uncertainty_score":0.9999852},"labels":[],"label_agreement":null},{"id":"W2083121683","doi":"10.1016/j.bmc.2007.07.026","title":"Selective angiotensin II AT2 receptor agonists devoid of the imidazole ring system","year":2007,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Vetenskapsrådet","keywords":"Chemistry; Agonist; Neurite; Imidazole; Angiotensin II; Moiety; Losartan; Stereochemistry; Valsartan; Receptor; Angiotensin receptor; Chemical synthesis; In vitro; Biochemistry; Internal medicine","score_opus":0.005499001137608732,"score_gpt":0.2112274319915808,"score_spread":0.20572843085397208,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083121683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949898,0.0012496979,0.001232247,0.00011051604,0.0004191265,0.00015455132,0.0000134819,0.000028187795,0.0018024058],"genre_scores_gemma":[0.9979533,0.000027617112,0.00042699376,0.00008226684,0.00086993596,0.0000036656818,0.00002608752,0.00003692933,0.00057318824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843675,0.000030685303,0.00040666104,0.00039623072,0.00033931495,0.00039038158],"domain_scores_gemma":[0.99895173,0.000018365414,0.0002473112,0.00044096014,0.00019779189,0.00014386671],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057582284,0.00023387952,0.00025911815,0.000019827448,0.00022864153,0.000009205307,0.0003738702,0.00030233033,0.000115538576],"category_scores_gemma":[0.00018540665,0.00017861242,0.00016279213,0.00023327219,0.00013432624,0.0000033429314,0.00021035432,0.00022382423,0.000004861556],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007751531,0.000037213755,0.00031489157,0.00010129677,0.00007034001,0.0000029987168,0.000121212994,0.0000023745645,0.9980439,0.0000235396,0.00073392515,0.00047080137],"study_design_scores_gemma":[0.0003725768,0.000092506976,0.00078698946,0.0002007113,0.000041386313,0.00008367566,0.00075748144,0.000015065895,0.9940584,0.00000527431,0.0033907099,0.00019524296],"about_ca_topic_score_codex":0.0000403897,"about_ca_topic_score_gemma":0.0000064226915,"teacher_disagreement_score":0.003985511,"about_ca_system_score_codex":0.00010332177,"about_ca_system_score_gemma":0.00018364967,"threshold_uncertainty_score":0.7283603},"labels":[],"label_agreement":null},{"id":"W2083172788","doi":"10.1016/j.actpsy.2010.09.003","title":"Visualizing the temporal dynamics of spatial information processing responsible for the Simon effect and its amplification by inhibition of return","year":2010,"lang":"en","type":"article","venue":"Acta Psychologica","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saint Mary's University; Dalhousie University","funders":"","keywords":"Inhibition of return; Task (project management); Dynamics (music); Identity (music); Sorting; Simon effect; Cognitive psychology; Computer science; Psychology; Neuroscience; Cognition; Visual attention; Algorithm; Physics; Economics","score_opus":0.009985934318626865,"score_gpt":0.2860017843219333,"score_spread":0.2760158500033064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083172788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9788518,0.00014955389,0.0200551,0.00038816,0.000086906875,0.0003809762,0.000025774356,0.000004579495,0.000057151556],"genre_scores_gemma":[0.99922997,0.000055181463,0.00037722534,0.00007261633,0.000041104096,0.00003224474,0.0001777427,0.000005071234,0.000008829606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951214,0.00004636127,0.00018853936,0.00010341948,0.000071922346,0.00007759644],"domain_scores_gemma":[0.9994621,0.00006194531,0.00023534287,0.00013688505,0.000090359616,0.000013313221],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00060768076,0.00006861098,0.000075886564,0.000014892612,0.000106485044,0.000021587133,0.00008937581,0.00012421304,0.000007145257],"category_scores_gemma":[0.00018463076,0.000038604798,0.000033547127,0.000041447813,0.000046646688,0.000012740163,0.000022956661,0.00007854454,1.424376e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021896687,0.000012397295,0.0002687923,0.000025660156,0.000006454758,9.31205e-9,0.000065480075,0.0000017304479,0.9816641,0.00013484251,0.00018368564,0.017417857],"study_design_scores_gemma":[0.00032782758,0.00051081186,0.0010783124,0.000014489547,0.000015009841,0.0000017760613,0.00010592207,0.0045990087,0.99065876,0.00020365491,0.0024221528,0.000062287785],"about_ca_topic_score_codex":0.000016574495,"about_ca_topic_score_gemma":0.000022470907,"teacher_disagreement_score":0.020378187,"about_ca_system_score_codex":0.000002560815,"about_ca_system_score_gemma":0.000013671505,"threshold_uncertainty_score":0.1574258},"labels":[],"label_agreement":null},{"id":"W2083342137","doi":"10.1016/s0169-328x(00)00120-0","title":"The splice variant D3nf reduces ligand binding to the D3 dopamine receptor: evidence for heterooligomerization","year":2000,"lang":"en","type":"article","venue":"Molecular Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Canada Research Chairs; University of Toronto","funders":"","keywords":"Biology; splice; Dopamine; Alternative splicing; Receptor; Ligand (biochemistry); Neuroscience; Dopamine receptor; Genetics; Gene; Gene isoform","score_opus":0.061955827492954155,"score_gpt":0.3779842600762683,"score_spread":0.31602843258331414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083342137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9717389,0.0021666915,0.013496929,0.010873329,0.00017680452,0.0011980715,0.000016926557,0.000013913713,0.00031845138],"genre_scores_gemma":[0.9896171,0.0011598523,0.0014107982,0.0007506412,0.00056335697,0.00048216493,0.00007528396,0.000060230315,0.005880557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976241,0.00044438313,0.0002570145,0.0005385244,0.00051130273,0.0006246749],"domain_scores_gemma":[0.9986217,0.0003431524,0.000042922435,0.0006163848,0.00023640631,0.00013941228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0032070447,0.00016289769,0.00012291857,0.00006739454,0.00091785676,0.00022978736,0.0007190926,0.00012277368,0.00008182372],"category_scores_gemma":[0.0012380189,0.000106141924,0.00011285959,0.00041395423,0.00010570023,0.000008757746,0.00016400324,0.00019598109,0.00007235551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022400373,0.000017287082,0.0000029099367,0.000010311508,0.000034232788,0.000002757986,0.00009925449,0.0003517783,0.9676201,0.00018638493,0.007349827,0.02410118],"study_design_scores_gemma":[0.00017589748,0.00043288252,0.000009134327,0.000051642783,0.000004912933,0.000008283426,0.00011961824,0.00027751934,0.81883013,0.00007583019,0.1798857,0.0001284166],"about_ca_topic_score_codex":0.000032567546,"about_ca_topic_score_gemma":0.000018086232,"teacher_disagreement_score":0.17253588,"about_ca_system_score_codex":0.000030281743,"about_ca_system_score_gemma":0.00010867023,"threshold_uncertainty_score":0.7059505},"labels":[],"label_agreement":null},{"id":"W2083748369","doi":"10.1016/s1043-2760(01)00498-2","title":"Receptor signaling and structure: insights from serotonin-1 receptors","year":2001,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Cell biology; Signal transduction; Receptor; G protein-coupled receptor kinase; G protein; Biology; MAPK/ERK pathway; Class C GPCR; Protein kinase A; 5-HT5A receptor; Phosphorylation; Biochemistry; Metabotropic receptor; Agonist","score_opus":0.023491292514329427,"score_gpt":0.2923461768625658,"score_spread":0.2688548843482364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083748369","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017656865,0.98040867,0.00003652047,0.000015173445,0.0012012473,0.00025105444,0.00011497883,0.000025315225,0.00029020204],"genre_scores_gemma":[0.001338333,0.9941783,0.0014910658,0.000071234244,0.00080365036,0.00007934856,0.0011021162,0.000081337945,0.0008546424],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971511,0.00038329477,0.00066198595,0.0011102685,0.0001272724,0.00056610774],"domain_scores_gemma":[0.99902904,0.00006183187,0.00028560925,0.00042706824,0.000032504024,0.00016395304],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008629248,0.0006949933,0.0016190175,0.0004629561,0.00012845288,0.000044332806,0.0002920836,0.0008867972,0.000675119],"category_scores_gemma":[0.000041664,0.00058239023,0.00022288901,0.00031737884,0.00018623532,0.000010967851,0.0002784411,0.0006401344,0.00000791875],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028107546,0.000025593257,0.000020243246,0.00020459025,0.00025435217,0.00002009394,0.00008628355,0.0000015693718,0.005082924,0.0007667481,0.00023718535,0.9932723],"study_design_scores_gemma":[0.00066799315,0.00006417558,0.000021126407,0.0004270116,0.00033505514,0.00008698195,0.000041974665,0.0000013111498,0.0040770336,0.00045302737,0.9932364,0.00058790745],"about_ca_topic_score_codex":0.000082858554,"about_ca_topic_score_gemma":0.00007428199,"teacher_disagreement_score":0.9929992,"about_ca_system_score_codex":0.00001778346,"about_ca_system_score_gemma":0.000061927945,"threshold_uncertainty_score":0.99966276},"labels":[],"label_agreement":null},{"id":"W2084006614","doi":"10.1160/th11-10-0740","title":"Simultaneous measurement of adenosine triphosphate release and aggregation potentiates human platelet aggregation responses for some subjects, including persons with Quebec platelet disorder","year":2012,"lang":"en","type":"article","venue":"Thrombosis and Haemostasis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Platelet; Platelet aggregation; Firefly protocol; Adenosine diphosphate; Luciferase; Adenosine triphosphate; Chemistry; Granule (geology); Epinephrine; Long-term potentiation; Whole blood; Adenosine monophosphate; Ristocetin; Adenosine; Pharmacology; Medicine; Internal medicine; Biochemistry; Biology","score_opus":0.04055096495363581,"score_gpt":0.28608159447503123,"score_spread":0.24553062952139543,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084006614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894525,0.00754901,0.0022752606,0.0001441369,0.000050029954,0.0004320348,0.00007745473,0.000013704141,0.000005897904],"genre_scores_gemma":[0.9968282,0.0013476266,0.0014031557,0.00005580852,0.00009637986,0.000035203226,0.00014055584,0.00003379318,0.000059259208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890757,0.00006308363,0.00025403802,0.00028891035,0.00020426286,0.00028213268],"domain_scores_gemma":[0.99935097,0.000051829942,0.00020265393,0.00015088433,0.0001368172,0.000106851025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040778998,0.0002090792,0.00027474135,0.00006855559,0.00032385843,0.00004490308,0.0000606531,0.00011278169,0.000016633276],"category_scores_gemma":[0.00010807108,0.00017642368,0.000058282592,0.000072339266,0.00009042556,0.000035081364,0.000047964208,0.00005675177,2.8333864e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010822406,0.00020256834,0.004514582,0.00022035392,0.00036763772,0.0000015819719,0.000943299,0.00012276377,0.92718303,0.0004109213,0.0001670125,0.064784035],"study_design_scores_gemma":[0.0018348565,0.000590752,0.0019602233,0.00015313402,0.00013915599,0.000010164013,0.00067526236,0.00023110273,0.99289244,0.00007330358,0.0011552187,0.0002844072],"about_ca_topic_score_codex":0.00053739443,"about_ca_topic_score_gemma":0.0003341476,"teacher_disagreement_score":0.06570941,"about_ca_system_score_codex":0.000029165058,"about_ca_system_score_gemma":0.00003815746,"threshold_uncertainty_score":0.71943486},"labels":[],"label_agreement":null},{"id":"W2084313269","doi":"10.1016/j.cjca.2014.01.017","title":"β-Adrenoceptors as Molecular Targets in the Treatment of Hypertension","year":2014,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Heterotrimeric G protein; G protein-coupled receptor kinase; G protein-coupled receptor; Adenylyl cyclase; Beta adrenergic receptor kinase; G protein; Medicine; cAMP-dependent pathway; Receptor; Signal transduction; Cell biology; Gs alpha subunit; GTPase-activating protein; Pharmacology; Internal medicine; Biology","score_opus":0.025996574642670793,"score_gpt":0.26473008654965785,"score_spread":0.23873351190698705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084313269","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021389779,0.99575317,0.00069219846,0.000026240898,0.00057981216,0.00020235885,0.00001271185,4.7176022e-7,0.00059404183],"genre_scores_gemma":[0.026193947,0.97271514,0.00008115146,0.00006764002,0.0008266178,0.000008753641,0.00005155859,0.000029246823,0.000025969535],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983277,0.00052463234,0.0005863,0.0001901696,0.00009548413,0.00027574552],"domain_scores_gemma":[0.9989605,0.000041861615,0.00039937263,0.00029798734,0.00011872791,0.00018154914],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043066964,0.00025029777,0.0013964374,0.00023397032,0.00003520516,0.000009977107,0.00036396505,0.0004290806,0.000019713607],"category_scores_gemma":[0.00009316136,0.0001543034,0.0008554564,0.00009618938,0.000083486906,0.0000014519716,0.000007910234,0.00016123541,0.000003745459],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003420799,0.000020291098,0.00006148347,0.00078078744,0.0013009099,0.0009792408,0.00020885559,0.0009959656,0.004012243,0.0003380083,0.0045783967,0.9866896],"study_design_scores_gemma":[0.00022079844,0.0012367698,0.0000035760324,0.00038922095,0.0002814203,0.00088770874,0.000038633785,3.4574467e-7,0.00070638076,0.00007127994,0.9960262,0.00013764756],"about_ca_topic_score_codex":0.00023572586,"about_ca_topic_score_gemma":0.00012662231,"teacher_disagreement_score":0.9914478,"about_ca_system_score_codex":0.00006937029,"about_ca_system_score_gemma":0.0011263884,"threshold_uncertainty_score":0.62923104},"labels":[],"label_agreement":null},{"id":"W2084359597","doi":"10.1159/000267472","title":"Localization of M <sub>3</sub> Muscarinic Receptor Subtype and mRNA in the Human Eye","year":2009,"lang":"en","type":"article","venue":"Ophthalmic Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Muscarinic acetylcholine receptor; Trabecular meshwork; In situ hybridization; Ciliary muscle; Corneal epithelium; Biology; Receptor; Messenger RNA; Corneal endothelium; Epithelium; Molecular biology; Glaucoma; Cell biology; Endocrinology; Endothelium; Neuroscience; Genetics; Gene","score_opus":0.0391514735479002,"score_gpt":0.3505390409721969,"score_spread":0.3113875674242967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084359597","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99704456,0.0006607091,0.00012458069,0.000105728395,0.00003145296,0.00020975192,0.0000024971994,0.0000024186586,0.0018182806],"genre_scores_gemma":[0.9991979,0.00045925152,0.000054444292,0.00003721784,0.00009629918,0.000010192884,0.000044158252,0.000009965438,0.00009057954],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873775,0.00027338087,0.00019529232,0.00025537176,0.00028902682,0.00024916616],"domain_scores_gemma":[0.99949425,0.000026050551,0.000044575456,0.00027776064,0.000115290306,0.000042045223],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001321887,0.00008490995,0.00010985621,0.0000926667,0.000112136615,0.000031717103,0.0002341547,0.00012679782,0.00003196917],"category_scores_gemma":[0.00010490378,0.00006605531,0.000037596532,0.00024201699,0.00008636307,0.0000048420047,0.000058733407,0.00018024561,0.000005348566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029222629,0.000055482105,0.0019072152,0.000013178764,0.0000051681736,0.0000033065248,0.00013679262,0.000027898779,0.99237907,0.00052829547,0.00029548004,0.0046188943],"study_design_scores_gemma":[0.00030373267,0.00065376423,0.0044795503,0.000031508276,0.0000023723173,0.000009618897,0.0002633746,0.000116536336,0.9918271,0.001208929,0.0010119575,0.00009157566],"about_ca_topic_score_codex":0.000034675144,"about_ca_topic_score_gemma":0.0000065697914,"teacher_disagreement_score":0.0045273188,"about_ca_system_score_codex":0.000012161348,"about_ca_system_score_gemma":0.00004611596,"threshold_uncertainty_score":0.26936573},"labels":[],"label_agreement":null},{"id":"W2084375425","doi":"10.1016/s0197-0186(00)00010-3","title":"Adrenergic Receptor Protocols","year":2000,"lang":"en","type":"article","venue":"Neurochemistry International","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Neuroscience; Adrenergic; Receptor; Medicine; Biology; Internal medicine","score_opus":0.008675469755044806,"score_gpt":0.2620400228609109,"score_spread":0.2533645531058661,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084375425","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.943633,0.00002526399,0.0002639985,0.00021188485,0.00022818567,0.0006031251,0.000024823463,0.000034167548,0.054975517],"genre_scores_gemma":[0.9574064,0.00006298069,0.0011843535,0.00071926106,0.0014964187,0.0010305896,0.000375984,0.00003622151,0.03768781],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991245,0.000014634179,0.00017393261,0.00032879598,0.00019980616,0.00015833387],"domain_scores_gemma":[0.99959135,0.0000040467216,0.00004469018,0.00021682127,0.00006892293,0.00007417318],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000054570817,0.00012900053,0.00007463844,0.000013854725,0.00004949001,0.000043565862,0.00034083996,0.000102929866,0.012621948],"category_scores_gemma":[0.00003380595,0.00013219185,0.00008738264,0.000037482765,0.000027354186,0.0000041782496,0.00004109874,0.000088430264,0.00010468237],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008067702,0.000047158137,0.00017573198,0.0000047715207,0.000019298734,0.000002396665,0.000005772192,0.00011315669,0.9879589,0.000046243505,0.006691912,0.0048539876],"study_design_scores_gemma":[0.00024987073,0.00004288217,0.00006498853,0.000009263121,0.0000015792158,0.000020415167,0.00000435198,0.00005206337,0.64451724,0.000031258696,0.3549053,0.00010076807],"about_ca_topic_score_codex":0.000001936314,"about_ca_topic_score_gemma":2.9064344e-7,"teacher_disagreement_score":0.3482134,"about_ca_system_score_codex":0.000010605667,"about_ca_system_score_gemma":0.00003584637,"threshold_uncertainty_score":0.98828065},"labels":[],"label_agreement":null},{"id":"W2084468980","doi":"10.1016/j.mce.2005.11.023","title":"Role of metal ions in ligand–receptor interaction: Insights from structural studies","year":2005,"lang":"en","type":"review","venue":"Molecular and Cellular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Chemistry; G protein-coupled receptor; Docking (animal); Biophysics; Agonist; Ligand (biochemistry); Metal ions in aqueous solution; Ternary complex; Homology modeling; Stereochemistry; Metal; Biochemistry; Biology; Enzyme","score_opus":0.021538763525825042,"score_gpt":0.29850819341921825,"score_spread":0.2769694298933932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084468980","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13211367,0.86706823,0.00006763776,0.000007719907,0.0003215191,0.00027940204,0.000033632223,0.0000088845145,0.00009932821],"genre_scores_gemma":[0.098938875,0.8996904,0.00040550448,0.000024259505,0.00024306656,0.00006164057,0.00052066374,0.00004990734,0.00006566529],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99790984,0.00026411653,0.00067492836,0.00067858514,0.00012763719,0.00034489046],"domain_scores_gemma":[0.9991461,0.000036390706,0.0002892913,0.00038736325,0.000065491346,0.00007535045],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000048075835,0.00047274385,0.0013520721,0.0002090503,0.000061798346,0.000016000338,0.00025951487,0.0003861064,0.00007232069],"category_scores_gemma":[0.000041192186,0.0004045896,0.0004117519,0.00012597804,0.0001341342,0.0000069693397,0.00030533705,0.00034620118,0.000008388551],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003058844,0.000055625722,0.0000041105955,0.0005770577,0.0011321674,0.000056628527,0.0003199053,0.00001541263,0.6079911,0.0010790937,0.00002211347,0.38871616],"study_design_scores_gemma":[0.0004045119,0.0001987333,6.9253457e-7,0.00059017836,0.00040865218,0.00006123341,0.0006820471,0.000008977661,0.32963353,0.00040474779,0.66715276,0.0004539089],"about_ca_topic_score_codex":0.000054073746,"about_ca_topic_score_gemma":0.0000472313,"teacher_disagreement_score":0.66713065,"about_ca_system_score_codex":0.000030934123,"about_ca_system_score_gemma":0.00007756396,"threshold_uncertainty_score":0.9998406},"labels":[],"label_agreement":null},{"id":"W2084497444","doi":"10.1210/endo.141.1.7259","title":"Intracellular Dynamics of sst5 Receptors in Transfected COS-7 Cells: Maintenance of Cell Surface Receptors during Ligand-Induced Endocytosis1","year":2000,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Internalization; Receptor; Cell biology; Biology; Cell surface receptor; Somatostatin receptor; Intracellular; G protein-coupled receptor; Cell membrane; Transfection; Cell; Biochemistry; Biophysics","score_opus":0.006174767184352932,"score_gpt":0.20586264001393223,"score_spread":0.1996878728295793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084497444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759823,0.0005065796,0.0003362593,0.000048635306,0.0004415786,0.00029811333,0.000026729074,0.000021388465,0.0007224617],"genre_scores_gemma":[0.9955949,0.002070861,0.0012636809,0.000017272523,0.000053959346,0.000013584929,0.000070423725,0.000047819176,0.0008674881],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978115,0.00019063611,0.00068332435,0.0005281472,0.0001551908,0.00063121086],"domain_scores_gemma":[0.9992345,0.000035123074,0.00015763205,0.0004013108,0.000086891014,0.00008454141],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015042914,0.00029374726,0.0005203738,0.000115518465,0.00004761802,0.0000062836107,0.00035343922,0.00027862052,0.0006533768],"category_scores_gemma":[0.000027965,0.00030679116,0.00021226419,0.00025973696,0.00013069986,0.000008324879,0.0000555961,0.00027636392,0.000015909969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032721917,0.00017427708,0.000830551,0.00008155593,0.000050671355,0.000012887619,0.0001987004,0.0015948641,0.99458593,0.00010208311,0.00004115003,0.002000135],"study_design_scores_gemma":[0.0016180304,0.00039988034,0.00013212176,0.000046603178,0.000021461487,0.000016853131,0.00029124692,0.0002751807,0.99602425,0.000039663526,0.0008566109,0.000278071],"about_ca_topic_score_codex":0.00020987896,"about_ca_topic_score_gemma":0.00014999168,"teacher_disagreement_score":0.0020033442,"about_ca_system_score_codex":0.000055506236,"about_ca_system_score_gemma":0.0000708985,"threshold_uncertainty_score":0.9999384},"labels":[],"label_agreement":null},{"id":"W2084878909","doi":"10.1016/s0091-3057(01)00725-0","title":"Increased drinking in mutant mice with truncated M5 muscarinic receptor genes","year":2002,"lang":"en","type":"article","venue":"Pharmacology Biochemistry and Behavior","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Medical Research Council","keywords":"Pilocarpine; Muscarinic acetylcholine receptor; Muscarinic acetylcholine receptor M1; Mutant; Muscarinic agonist; Agonist; Receptor; Wild type; Muscarinic acetylcholine receptor M3; Muscarinic acetylcholine receptor M2; Muscarinic acetylcholine receptor M4; Internal medicine; Biology; Endocrinology; Chemistry; Pharmacology; Gene; Medicine; Biochemistry; Epilepsy","score_opus":0.013931756190161682,"score_gpt":0.2540161915585682,"score_spread":0.2400844353684065,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084878909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977043,0.0015786416,0.000027780461,0.00007831503,0.00016081127,0.00023595108,0.000018155086,0.000025304631,0.0001706977],"genre_scores_gemma":[0.99777114,0.0006303036,0.00052521616,0.00022109682,0.00023993579,0.00014528845,0.00011434226,0.000029560828,0.0003231126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864745,0.000062009334,0.00025678938,0.0005599484,0.000104274666,0.00036953998],"domain_scores_gemma":[0.9995183,0.000016010872,0.00009848051,0.00016451335,0.000055022843,0.00014766755],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014985306,0.0002585552,0.00022167616,0.0000495281,0.00010698326,0.000023607996,0.00017944584,0.0002683984,0.0009878941],"category_scores_gemma":[0.0000105144345,0.00023676187,0.000055049804,0.00013565851,0.0001304504,0.0000069658627,0.000090959125,0.0002055722,0.000008068493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012721254,0.00028672308,0.009171709,0.00002684202,0.000038703038,0.000041868792,0.000043066306,0.000004474867,0.98700976,0.0000012886138,0.00022441482,0.0030239436],"study_design_scores_gemma":[0.0017122957,0.00020043041,0.0007427905,0.000020358853,0.00012535736,0.00010476701,0.000092357746,0.0000954275,0.9944904,0.0000017444863,0.0020873467,0.00032671346],"about_ca_topic_score_codex":0.000031064217,"about_ca_topic_score_gemma":0.000011183835,"teacher_disagreement_score":0.008428918,"about_ca_system_score_codex":0.000025300915,"about_ca_system_score_gemma":0.000033765373,"threshold_uncertainty_score":0.9999253},"labels":[],"label_agreement":null},{"id":"W2085108751","doi":"10.1016/j.ejphar.2003.08.055","title":"Non-amine-based dopamine transporter (reuptake) inhibitors retain properties of amine-based progenitors","year":2003,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Center for Research Resources; National Institute on Drug Abuse; National Institute of Mental Health","keywords":"Monoamine neurotransmitter; Chemistry; Amine gas treating; Pharmacology; Biogenic amine; Reuptake; Transporter; Dopamine; Dopamine transporter; Biochemistry; Receptor; Biology; Serotonin; Neuroscience; Organic chemistry; Gene","score_opus":0.014580811323488095,"score_gpt":0.23300669168184335,"score_spread":0.21842588035835525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085108751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99101657,0.0010701487,0.006266523,0.00016414686,0.0008719949,0.00023035296,0.000007134832,0.00000723817,0.000365872],"genre_scores_gemma":[0.9966433,0.000045046832,0.0020718204,0.0003916326,0.0006145446,0.0000043002033,0.0000116075935,0.00006348293,0.00015428917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99773896,0.0005770334,0.0008738513,0.00025444792,0.0002351326,0.00032058565],"domain_scores_gemma":[0.99873364,0.000014039129,0.0006000388,0.00015758847,0.0003419017,0.0001527922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012138267,0.00026167068,0.0003738847,0.00016916113,0.000061808605,0.000012353639,0.0003057095,0.000080680285,0.0002472819],"category_scores_gemma":[0.000054672368,0.00021072688,0.0003035738,0.0001401613,0.00014788861,0.000009456599,0.000017444636,0.0002490208,0.0000054080356],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005195843,0.00024393683,0.0007429582,0.000072027884,0.00013442668,0.00014804005,0.000060762366,0.0011354551,0.9948133,0.000002840506,0.0013405539,0.0007860748],"study_design_scores_gemma":[0.003181313,0.0018038806,0.00014067024,0.00006609349,0.00013137536,0.000053215426,0.00006719924,0.00014561464,0.971783,0.00000152436,0.02240776,0.00021834426],"about_ca_topic_score_codex":0.0000012185322,"about_ca_topic_score_gemma":7.6751274e-7,"teacher_disagreement_score":0.02303033,"about_ca_system_score_codex":0.000021144617,"about_ca_system_score_gemma":0.00024101407,"threshold_uncertainty_score":0.85931927},"labels":[],"label_agreement":null},{"id":"W2085367047","doi":"10.1007/bf03019970","title":"Reserpine prevents cvs dysfunction after raised icp in rats","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Anesthesia/Journal canadien d anesthésie","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Queen's University; Canadian Anesthesiologists' Society","keywords":"Reserpine; Medicine; Internal medicine; Pharmacology","score_opus":0.008252482497738982,"score_gpt":0.2191424169759968,"score_spread":0.2108899344782578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085367047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962354,0.0018370249,0.00032391018,0.00059913564,0.0005110952,0.00013654867,0.0000025911918,0.0000024611802,0.0003518463],"genre_scores_gemma":[0.99723756,0.00009386825,0.000521968,0.00015155949,0.0011415955,0.0000026131765,0.000009917156,0.000051715637,0.0007891712],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.99745077,0.00014438611,0.0008918943,0.00025787536,0.0003535954,0.0009014646],"domain_scores_gemma":[0.99727494,0.00002079186,0.00045801283,0.0002317846,0.00040202605,0.0016124323],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0025598083,0.00028766345,0.00038201135,0.0007306117,0.00020695709,0.0001292447,0.00044473907,0.00031065234,0.0004030397],"category_scores_gemma":[0.00017397913,0.00026984935,0.00024815043,0.00033207986,0.000090289635,0.000048678772,0.000010815539,0.000581493,0.0000072654198],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028075634,0.00015624064,0.043252565,0.00007838237,0.00028628984,0.8189597,0.001673584,0.001395473,0.10947149,0.00017954256,0.008872496,0.012866683],"study_design_scores_gemma":[0.0022448085,0.0021871466,0.022744725,0.00034225028,0.000060185044,0.8857955,0.0007858291,0.00001886378,0.031699024,0.0004379962,0.05298596,0.00069775834],"about_ca_topic_score_codex":0.0019251422,"about_ca_topic_score_gemma":0.025957359,"teacher_disagreement_score":0.07777247,"about_ca_system_score_codex":0.0003843562,"about_ca_system_score_gemma":0.0020284671,"threshold_uncertainty_score":0.9999754},"labels":[],"label_agreement":null},{"id":"W2085505560","doi":"10.1016/j.bmc.2006.05.062","title":"2-(4,5-Dihydroimidazol-2-yl)benzimidazoles as highly selective imidazoline I2/adrenergic α2 receptor ligands","year":2006,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Imidazoline receptor; Selectivity; Stereochemistry; Receptor; Chemical synthesis; Medicinal chemistry; Biochemistry; In vitro; Pharmacology; Catalysis","score_opus":0.0037126567071239513,"score_gpt":0.20712816986537208,"score_spread":0.20341551315824813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085505560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885762,0.0043762084,0.00042970935,0.0005009743,0.00046596566,0.00021990224,0.00004599327,0.00013088675,0.0052541806],"genre_scores_gemma":[0.9902659,0.0005832566,0.00036052984,0.00035939628,0.0041163685,0.00004025869,0.0008865006,0.00012502316,0.0032627615],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967162,0.00004345184,0.0007107073,0.0010697623,0.00062324665,0.0008366451],"domain_scores_gemma":[0.9983407,0.00003313558,0.00031881736,0.00067538786,0.00027341128,0.00035849607],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003783691,0.00064426375,0.0005425874,0.000057210884,0.0002668502,0.00006677836,0.0006024136,0.00067173864,0.0013673898],"category_scores_gemma":[0.00016085041,0.0006016706,0.00026596326,0.00039030684,0.00021099512,0.000013342329,0.00019964519,0.00043107633,0.00011601946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018181854,0.00016560948,0.00040864045,0.00007076783,0.00010438073,0.000024589139,0.000038142247,0.000039292976,0.98929113,0.00011420678,0.009021507,0.00053992565],"study_design_scores_gemma":[0.0012927043,0.00022571938,0.00025633821,0.00008846462,0.0000972379,0.00017543582,0.0001728683,0.000058632344,0.9760786,0.00035132252,0.02050888,0.0006937826],"about_ca_topic_score_codex":0.00024396092,"about_ca_topic_score_gemma":0.000024255254,"teacher_disagreement_score":0.013212505,"about_ca_system_score_codex":0.0001254271,"about_ca_system_score_gemma":0.00038460203,"threshold_uncertainty_score":0.99964345},"labels":[],"label_agreement":null},{"id":"W2085646162","doi":"10.3389/fnins.2015.00146","title":"Ancient interaction between the teneurin C-terminal associated peptides (TCAP) and latrophilin ligand-receptor coupling: a role in behavior","year":2015,"lang":"en","type":"review","venue":"Frontiers in Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"G protein-coupled receptor; Biology; Transmembrane protein; Receptor; Cell biology; Neuroscience; Biochemistry","score_opus":0.03499559903915439,"score_gpt":0.306556938763304,"score_spread":0.2715613397241496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085646162","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.30512962,0.69203895,0.00017427362,0.000013943179,0.0017365742,0.0008110275,0.000064039436,0.000012241852,0.00001933517],"genre_scores_gemma":[0.056137886,0.942655,0.00032198572,0.000066272674,0.0002631393,0.00019401546,0.000108008346,0.00005507728,0.00019858166],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99791753,0.00015463743,0.00049919693,0.0007523188,0.00027558632,0.0004007446],"domain_scores_gemma":[0.9992312,0.000023527924,0.0003008587,0.00028750894,0.0000454984,0.00011137287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008367568,0.00032306294,0.0006667113,0.00019355546,0.000103907085,0.00010599852,0.00051178527,0.00028226423,0.0000016793824],"category_scores_gemma":[0.00023020715,0.00024361652,0.00013783267,0.00038365982,0.00016532245,0.000015496567,0.0002393616,0.00046023395,0.0000015681005],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008160046,0.00057504064,0.04058993,0.0010987144,0.000046764097,0.000120009,0.0004243034,0.00030819487,0.07749413,0.0000103344455,0.0036968654,0.8755541],"study_design_scores_gemma":[0.00059843156,0.0006658529,0.0018964246,0.0019430204,0.00021028947,0.00006144883,0.00024618598,0.0009746015,0.0027226785,0.00003304807,0.9897718,0.00087621814],"about_ca_topic_score_codex":0.000018084616,"about_ca_topic_score_gemma":0.000011767833,"teacher_disagreement_score":0.9860749,"about_ca_system_score_codex":0.0001087228,"about_ca_system_score_gemma":0.00019770344,"threshold_uncertainty_score":0.9934394},"labels":[],"label_agreement":null},{"id":"W2085744412","doi":"10.1016/j.automatica.2013.03.020","title":"Lagrangian methods for approximating the viability kernel in high-dimensional systems","year":2013,"lang":"en","type":"article","venue":"Automatica","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":138,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Institute for Computing, Information and Cognitive Systems; Princeton University; National Science Foundation","keywords":"Reachability; Kernel (algebra); Mathematics; Linear system; Mathematical optimization; Kernel method; Connection (principal bundle); Algorithm; Computer science; Applied mathematics; Support vector machine; Discrete mathematics; Artificial intelligence","score_opus":0.011430880203756844,"score_gpt":0.2853689838813966,"score_spread":0.27393810367763977,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085744412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8116809,0.0002451934,0.1860934,0.00033623277,0.00025327128,0.0011452204,0.0000049564105,0.000025241436,0.00021557152],"genre_scores_gemma":[0.849453,0.0000013368249,0.14976093,0.00012776513,0.00008854378,0.0003978689,0.00002555255,0.000015175098,0.00012984428],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9989976,0.00019026693,0.00029776822,0.00021973034,0.00007981599,0.00021481229],"domain_scores_gemma":[0.9993975,0.00014116845,0.00008276036,0.00027172017,0.000065831206,0.000040979365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010366532,0.00010791262,0.00015949337,0.000019176114,0.000086848246,0.000048389258,0.00015735143,0.00010010958,0.00006670355],"category_scores_gemma":[0.0002499457,0.00007112729,0.0000705708,0.000059765167,0.000033856304,0.000004424015,0.000057753346,0.00006004321,0.0000125397155],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000088010565,0.000055244298,0.00014204215,0.000115613184,0.000040620103,1.6375526e-7,0.00013466037,0.00069375336,0.97894216,0.003562417,0.00061672257,0.015687833],"study_design_scores_gemma":[0.0009897652,0.0002527935,0.0025589883,0.00007888993,0.000034180575,0.0000130942435,0.00053737155,0.72246754,0.2564512,0.013081581,0.0031055564,0.00042908298],"about_ca_topic_score_codex":0.00014604008,"about_ca_topic_score_gemma":0.000004099892,"teacher_disagreement_score":0.72249097,"about_ca_system_score_codex":0.000012431316,"about_ca_system_score_gemma":0.00002727295,"threshold_uncertainty_score":0.29004866},"labels":[],"label_agreement":null},{"id":"W2086015992","doi":"10.1074/jbc.m401923200","title":"Dopamine D1 and D2 Receptor Co-activation Generates a Novel Phospholipase C-mediated Calcium Signal","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":455,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Dopamine receptor D2; Cell biology; D1-like receptor; Phospholipase C; Immune receptor; Signal transduction; Pertussis toxin; Agonist; Biology; D2-like receptor; G protein-coupled receptor; Dopamine receptor; Endogenous agonist; G protein; Class C GPCR; Dopamine; Dopamine receptor D1; Metabotropic receptor; Biochemistry; Endocrinology","score_opus":0.024864781566266526,"score_gpt":0.2586281893808948,"score_spread":0.2337634078146283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086015992","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907986,0.00059588894,0.008163691,0.00017066539,0.00007192246,0.000057609475,0.000031980297,0.0000073948736,0.000102281745],"genre_scores_gemma":[0.99534595,0.0003213489,0.0031587817,0.00021450718,0.0007232044,0.000003834379,0.00015112998,0.0000132452005,0.00006800553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989749,0.000020488875,0.00039869806,0.00023758173,0.00015072928,0.00021760642],"domain_scores_gemma":[0.9992114,0.000026767088,0.00030460907,0.00010080974,0.00016936315,0.00018710876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026880187,0.00018852338,0.0002496479,0.00001991805,0.00007151186,0.00003333086,0.00014725102,0.0003214433,0.00026346874],"category_scores_gemma":[0.00020083983,0.00013621523,0.00011812665,0.00007144956,0.000099239274,0.000008377687,0.000048566097,0.00022171035,0.0000028508305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023949395,0.0001338081,0.00026638454,0.000013758239,0.00004792255,0.0000068315253,0.00001249796,0.00010350136,0.99865437,0.0000084020485,0.00016962238,0.0003434129],"study_design_scores_gemma":[0.0012972567,0.0004752716,0.00014948811,0.000033776185,0.000010226972,0.00012981103,0.00008165659,0.000016009084,0.99239135,0.000055360637,0.0051758927,0.00018389411],"about_ca_topic_score_codex":0.000004837194,"about_ca_topic_score_gemma":1.08856206e-7,"teacher_disagreement_score":0.006263008,"about_ca_system_score_codex":0.000036276953,"about_ca_system_score_gemma":0.00009085445,"threshold_uncertainty_score":0.5554696},"labels":[],"label_agreement":null},{"id":"W2086120337","doi":"10.1139/o00-075","title":"New thoughts on the role of the βγ subunit in G protein signal transduction","year":2000,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Heterotrimeric G protein; G protein; Signal transduction; Cell biology; Effector; GTPase-activating protein; Adenylyl cyclase; G protein-coupled receptor; Protein subunit; Biology; G beta-gamma complex; Gs alpha subunit; Receptor; cAMP-dependent pathway; G alpha subunit; GTP-binding protein regulators; Biochemistry; Chemistry","score_opus":0.011454472047360127,"score_gpt":0.23252658187096006,"score_spread":0.22107210982359993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086120337","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.019286647,0.9781506,0.000018688153,0.000026628079,0.00008169307,0.0005041933,0.000044426244,0.000004415645,0.0018827168],"genre_scores_gemma":[0.034217738,0.9624854,0.000051246396,0.000029065386,0.00074377685,0.00007007422,0.00016200703,0.000029470073,0.0022112494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998688,0.00021429597,0.00036068942,0.0004427923,0.000069982954,0.0002242865],"domain_scores_gemma":[0.9993172,0.000027197173,0.00019999487,0.00038751698,0.000016383188,0.0000516808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019155328,0.00030795083,0.00045509005,0.000025642423,0.00007448314,0.000010944274,0.00037475652,0.0006992063,0.0002404588],"category_scores_gemma":[0.000011902671,0.00017079704,0.0002670731,0.00012614552,0.0001121847,0.0000011755003,0.00005856927,0.00031546617,0.0000031591944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034762546,0.00003669256,0.0000018443822,0.00048670973,0.000031415046,3.7143033e-7,0.00001483162,0.000001041346,0.64054155,0.000069577116,0.000066763634,0.35871443],"study_design_scores_gemma":[0.00007520297,0.00007134674,1.1070819e-7,0.00036616396,0.000031648065,0.0000054414,0.00001828661,6.089596e-7,0.51717603,0.00016439473,0.48197612,0.000114632116],"about_ca_topic_score_codex":0.000019005698,"about_ca_topic_score_gemma":0.000003080677,"teacher_disagreement_score":0.48190936,"about_ca_system_score_codex":0.000012144017,"about_ca_system_score_gemma":0.0002090049,"threshold_uncertainty_score":0.6964901},"labels":[],"label_agreement":null},{"id":"W2086399366","doi":"10.1016/j.cellsig.2006.03.003","title":"ARF6 activation by Gαq signaling: Gαq forms molecular complexes with ARNO and ARF6","year":2006,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Fleurimont; Université de Sherbrooke","funders":"","keywords":"Internalization; G protein-coupled receptor; Guanine nucleotide exchange factor; G protein; Receptor; Cell biology; Mutant; Chemistry; Immunoprecipitation; ADP ribosylation factor; Signal transduction; Biology; Biochemistry; Gene","score_opus":0.0048064125497027255,"score_gpt":0.1860582168846788,"score_spread":0.18125180433497606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086399366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.68369794,0.0013610452,0.31413954,0.00003838382,0.0000313704,0.00019773036,0.0000075495077,0.000027850087,0.0004986032],"genre_scores_gemma":[0.99490577,0.000033807017,0.003598408,0.00015981306,0.00020898625,0.000025084142,0.00059189607,0.000071183844,0.00040503743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983189,0.00005653703,0.00032793483,0.0005920398,0.00028137295,0.00042322552],"domain_scores_gemma":[0.9993239,0.000021879783,0.00018172977,0.00024508123,0.00011042552,0.000116951756],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002467988,0.00033049626,0.00026253783,0.00006640482,0.00022048016,0.00012383838,0.00017816808,0.0002112757,0.000068156936],"category_scores_gemma":[0.000010948071,0.00029067436,0.0000979619,0.00012276246,0.00008327771,0.000017278231,0.0000484096,0.00016407057,0.0000048718475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007410217,0.000056519984,0.00025566242,0.000032921627,0.00005835792,0.000010144502,0.00003473966,0.0025809307,0.9955075,0.00087690353,0.0001931023,0.00031915674],"study_design_scores_gemma":[0.0006601206,0.00026495574,0.000013251267,0.00006183842,0.0000390867,0.0000102861495,0.0001265736,0.000859882,0.9914893,0.0009680095,0.0050694467,0.00043722923],"about_ca_topic_score_codex":0.000053179338,"about_ca_topic_score_gemma":0.000004237895,"teacher_disagreement_score":0.31120786,"about_ca_system_score_codex":0.00001992659,"about_ca_system_score_gemma":0.000041050385,"threshold_uncertainty_score":0.9999545},"labels":[],"label_agreement":null},{"id":"W2086779090","doi":"10.1016/j.pnpbp.2013.07.006","title":"Are dopamine D2 receptors out of control in psychosis?","year":2013,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dopamine receptor D2; D2-like receptor; Receptor; Dopamine receptor; Dopamine; Amphetamine; D1-like receptor; Psychosis; Dopamine receptor D3; Pharmacology; Psychology; Neuroscience; Internal medicine; Chemistry; Endocrinology; Biology; Medicine; Psychiatry","score_opus":0.03703615207065289,"score_gpt":0.3509259918823564,"score_spread":0.3138898398117035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086779090","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04008275,0.9534243,0.000021457276,0.00019416002,0.0045073996,0.0016198113,0.000053774213,0.00002089041,0.000075460295],"genre_scores_gemma":[0.015032124,0.98221815,0.00041057265,0.00078429625,0.000606842,0.0007723585,0.00007999888,0.000056667224,0.00003899058],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99586296,0.00080875866,0.0012939174,0.0012625294,0.00013519161,0.00063666794],"domain_scores_gemma":[0.99825585,0.00013235168,0.0010162251,0.00036462667,0.000059963073,0.00017096737],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00052416587,0.00071713206,0.0018802613,0.00030553612,0.0000564363,0.000022148544,0.0006026353,0.0014363022,0.0002559795],"category_scores_gemma":[0.000072196606,0.0005217018,0.00040955862,0.00031347727,0.00044133925,0.000008046517,0.00016063647,0.0009173462,0.000016104043],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010178926,0.0016515335,0.32919255,0.0041647945,0.0003690026,0.00003556521,0.000017181253,0.0000019913755,0.0004526328,0.00011633753,0.005436635,0.6575439],"study_design_scores_gemma":[0.00536295,0.0015139068,0.00896779,0.0024560213,0.0002321023,0.00004764089,0.000039628812,0.000009906822,0.000029630572,0.00035015633,0.97986424,0.001126025],"about_ca_topic_score_codex":0.0000019782308,"about_ca_topic_score_gemma":0.0000136777435,"teacher_disagreement_score":0.9744276,"about_ca_system_score_codex":0.000016227981,"about_ca_system_score_gemma":0.000064594235,"threshold_uncertainty_score":0.99986005},"labels":[],"label_agreement":null},{"id":"W2086807823","doi":"10.1074/jbc.m111.305656","title":"Cys-27 Variant of Human δ-Opioid Receptor Modulates Maturation and Cell Surface Delivery of Phe-27 Variant via Heteromerization","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Biocenter, University of Oulu; Sigrid Juséliuksen Säätiö; Suomen Kulttuurirahasto","keywords":"Endoplasmic reticulum; Cell biology; HEK 293 cells; Receptor; Opioid receptor; Calnexin; G protein-coupled receptor; Biology; Cell; Chaperone (clinical); Chemistry; Agonist; Signal transduction; Biochemistry","score_opus":0.016233751883396607,"score_gpt":0.21213213517531887,"score_spread":0.19589838329192227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086807823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99355876,0.00074244867,0.005304005,0.000008276416,0.0001275831,0.000059654496,0.000017254897,0.000003141142,0.0001788728],"genre_scores_gemma":[0.99329025,0.00063493755,0.0058043995,0.0000151962295,0.00012946031,5.3161455e-7,0.000055308046,0.000010068431,0.00005987977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989276,0.000056113935,0.0005652623,0.00019071961,0.00012185849,0.00013845679],"domain_scores_gemma":[0.99889565,0.000015707557,0.0006550633,0.00013575991,0.00021448953,0.00008334105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027698127,0.00015135604,0.00030198315,0.000017554317,0.00003658975,0.000009099859,0.00016235835,0.00030016937,0.00027422627],"category_scores_gemma":[0.0000378776,0.00011256475,0.0001273801,0.000053858774,0.000086413194,0.000010498729,0.00006770249,0.00012664696,5.848555e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022984507,0.00013588565,0.00052201696,0.00007258568,0.000050804505,0.0000051536076,0.000070461836,0.000039570237,0.9986661,0.000009218632,0.000039988525,0.00015836695],"study_design_scores_gemma":[0.00040415287,0.0006877354,0.0004662183,0.000041792755,0.000026238282,0.0000597921,0.00008257785,0.0000847689,0.9976902,0.00024718908,0.0000805618,0.00012877144],"about_ca_topic_score_codex":0.0000097974225,"about_ca_topic_score_gemma":2.001124e-7,"teacher_disagreement_score":0.0009759011,"about_ca_system_score_codex":0.000010145078,"about_ca_system_score_gemma":0.000028983346,"threshold_uncertainty_score":0.4590257},"labels":[],"label_agreement":null},{"id":"W2086889423","doi":"10.1038/nchembio0309-131","title":"Building a new conceptual framework for receptor heteromers","year":2009,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":392,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute on Drug Abuse; National Institute of Mental Health; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas; Medizinische Universität Graz; National Institutes of Health; U.S. Department of Health and Human Services; Karl-Franzens-Universität Graz; King's College London; Université de Montpellier; Universitat de Barcelona; Centre National de la Recherche Scientifique; University of Toronto; Universidad de Navarra; Karolinska Institutet; University of Glasgow; Institut National de la Santé et de la Recherche Médicale","keywords":"Computational biology; Drug discovery; G protein-coupled receptor; Identification (biology); Signal transduction; Class (philosophy); Transmembrane protein; Data science; Biology; Receptor; Computer science; Bioinformatics; Biochemistry; Artificial intelligence; Ecology","score_opus":0.010400013140719994,"score_gpt":0.2968832559023345,"score_spread":0.2864832427616145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2086889423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8298371,0.0035314974,0.16366045,0.0014719778,0.0009026559,0.0003293964,0.00004391627,0.00004990663,0.00017313108],"genre_scores_gemma":[0.8298156,0.000056288634,0.16512726,0.0030464293,0.0015941302,0.000011546694,0.00024252926,0.0000181359,0.000088030065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988153,0.000025563928,0.00020018658,0.0005056025,0.000062431434,0.00039093726],"domain_scores_gemma":[0.9994181,0.00005956469,0.000077471406,0.0002208551,0.00006323873,0.0001607737],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00010406947,0.00020179397,0.0002323306,0.000028343808,0.00005088795,0.000014386452,0.00028243638,0.0014163106,0.000120493365],"category_scores_gemma":[0.00049834634,0.00017664702,0.00018341515,0.000077460776,0.00007857694,0.0000025672382,0.000045968085,0.00041312378,0.0000059818494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015083337,0.000020703048,0.000015648964,0.0000026238008,0.000028013364,1.7477772e-7,0.00001714798,0.00000163567,0.94203496,0.040230002,0.0049202307,0.012578008],"study_design_scores_gemma":[0.00041945506,0.00041163224,0.0000042826796,0.000012357934,0.00000916551,0.0000043953382,0.000015371941,0.0000046343916,0.8389294,0.025942845,0.13404378,0.00020268207],"about_ca_topic_score_codex":0.0000012163356,"about_ca_topic_score_gemma":1.725503e-7,"teacher_disagreement_score":0.12912355,"about_ca_system_score_codex":0.000018702205,"about_ca_system_score_gemma":0.00004953487,"threshold_uncertainty_score":0.9998801},"labels":[],"label_agreement":null},{"id":"W2087151025","doi":"10.1016/j.cellsig.2006.07.021","title":"Signalling complexes associated with adenylyl cyclase II are assembled during their biosynthesis","year":2006,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Adenylyl cyclase; Heterotrimeric G protein; G protein; Cell biology; Chemistry; Receptor; Gs alpha subunit; Signal transduction; GTPase; Agonist; Biochemistry; Biology","score_opus":0.009146177668617158,"score_gpt":0.1853111438821045,"score_spread":0.17616496621348735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087151025","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96282303,0.001709319,0.034611087,0.00004281089,0.00010032831,0.0002764872,0.000025425234,0.00010372922,0.00030779024],"genre_scores_gemma":[0.9973131,0.00004686313,0.0010432352,0.000052838244,0.00055435114,0.000030247073,0.00027627192,0.00012038118,0.00056272646],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975407,0.00015275135,0.0004939822,0.0007703665,0.000349003,0.0006931785],"domain_scores_gemma":[0.99886566,0.0000659221,0.00038449708,0.0003403733,0.00019613706,0.00014738378],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042668276,0.00048738142,0.0004626157,0.000123848,0.0007434827,0.00013369785,0.00036869082,0.00032156374,0.00017027685],"category_scores_gemma":[0.000057410478,0.00042505097,0.0002551589,0.0002431642,0.000060241124,0.00001568936,0.00013790405,0.00024451085,0.000009961752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009388691,0.00015334442,0.00081289635,0.000031667012,0.00017202618,0.000047979298,0.00004700026,0.010115457,0.98833,0.000070894035,0.00004317848,0.00008168796],"study_design_scores_gemma":[0.0008088862,0.00019830007,0.0002893133,0.00027461565,0.00007634638,0.0000101598125,0.0002323058,0.0020443017,0.99477506,0.00018227751,0.0004801133,0.00062832166],"about_ca_topic_score_codex":0.000038150283,"about_ca_topic_score_gemma":0.00006719263,"teacher_disagreement_score":0.034490064,"about_ca_system_score_codex":0.000055699213,"about_ca_system_score_gemma":0.00006414068,"threshold_uncertainty_score":0.9998201},"labels":[],"label_agreement":null},{"id":"W2087552697","doi":"10.1074/jbc.m610038200","title":"Differential Repression by Freud-1/CC2D1A at a Polymorphic Site in the Dopamine-D2 Receptor Gene","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Biology; Regulation of gene expression; Gene; Repressor; Gene knockdown; Genetics; Chromatin immunoprecipitation; Allele; Nuclear receptor; Transcriptional regulation; Psychological repression; Dopamine receptor D2; Gene expression; Receptor; Transcription factor; Promoter","score_opus":0.012865303105430062,"score_gpt":0.2425550037565769,"score_spread":0.22968970065114686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087552697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99631125,0.0018265627,0.0012494684,0.00014682533,0.00015449898,0.00006560174,0.000017837676,0.0000042673832,0.00022370521],"genre_scores_gemma":[0.99768174,0.00045081857,0.0003589487,0.00021015055,0.00085318775,0.0000025161244,0.00010436689,0.000011351931,0.00032690584],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985377,0.00008228095,0.0005513661,0.0002721675,0.00024296352,0.0003135196],"domain_scores_gemma":[0.9991556,0.000059286704,0.00035161397,0.00023882338,0.00007161999,0.00012306024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007380438,0.0001906317,0.0002498191,0.000021567887,0.00008109491,0.000024211084,0.00039762276,0.0003895831,0.00062058406],"category_scores_gemma":[0.00018555163,0.000108896245,0.00021365807,0.000090857604,0.000078334655,0.000004258977,0.00013469005,0.0003268085,0.000004528585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041755248,0.00012163685,0.0035092658,0.000007343261,0.00002128348,0.000029644325,0.00002726836,0.0000039132124,0.9932346,0.0000010243368,0.0019930017,0.00063348195],"study_design_scores_gemma":[0.00062553264,0.00026217173,0.0010798764,0.000024823401,0.000010153298,0.000210743,0.00008745945,0.0000051735706,0.98852044,0.000025014739,0.008995348,0.00015325705],"about_ca_topic_score_codex":0.000004235517,"about_ca_topic_score_gemma":0.0000012792295,"teacher_disagreement_score":0.0070023458,"about_ca_system_score_codex":0.000038847145,"about_ca_system_score_gemma":0.00002317187,"threshold_uncertainty_score":0.67949605},"labels":[],"label_agreement":null},{"id":"W2087663632","doi":"10.1038/nature13430","title":"Visualization of arrestin recruitment by a G-protein-coupled receptor","year":2014,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":508,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Arrestin; G protein-coupled receptor; Receptor; Rhodopsin; Biophysics; Cell biology; Transmembrane domain; Transmembrane protein; Protein–protein interaction; Chemistry; Biology; Biochemistry","score_opus":0.010173359115439455,"score_gpt":0.2715242537776138,"score_spread":0.26135089466217437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2087663632","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9761326,0.0013595835,0.021154713,0.00012567706,0.00029504282,0.0003636633,0.000014860568,0.00001526792,0.00053862133],"genre_scores_gemma":[0.9964362,0.00004244436,0.0020026257,0.0002633547,0.00018773825,0.00003089727,0.0002852604,0.000017867214,0.00073361024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993512,0.00005059222,0.00014030862,0.00020552894,0.0001349789,0.000117407086],"domain_scores_gemma":[0.99959874,0.0000059920785,0.00009344959,0.00017364333,0.00008563438,0.000042550335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020088156,0.0000960398,0.00010688099,0.000020146175,0.000033179072,0.000008837057,0.000109022985,0.0006669264,0.00014468149],"category_scores_gemma":[0.00014048483,0.00008490534,0.000052230935,0.00006710482,0.000015449543,0.0000017444859,0.000030072239,0.00019762253,0.000005107144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035835757,0.000027812112,0.00006133521,0.000014232959,0.0000133650765,5.670005e-8,0.000013518326,0.000010800441,0.9912095,0.0009546005,0.005888524,0.0017704056],"study_design_scores_gemma":[0.00026756022,0.00020064446,0.000018222934,0.00002213439,0.0000050508183,4.6815526e-7,0.000010387673,0.00024890914,0.8811281,0.00012534004,0.11788136,0.00009185709],"about_ca_topic_score_codex":0.0000052116357,"about_ca_topic_score_gemma":0.0000019168858,"teacher_disagreement_score":0.111992836,"about_ca_system_score_codex":0.000007252085,"about_ca_system_score_gemma":0.000017968565,"threshold_uncertainty_score":0.5143947},"labels":[],"label_agreement":null},{"id":"W2088550661","doi":"10.1016/j.ab.2008.05.047","title":"Capture of an activated receptor complex from the surface of live cells by affinity receptor chromatography","year":2008,"lang":"en","type":"article","venue":"Analytical Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Langley Research Center","keywords":"Receptor; 5-HT5A receptor; Cell biology; Biology; Cell surface receptor; Immune receptor; Affinity chromatography; Biochemistry; Molecular biology; Chemistry","score_opus":0.013807724420946096,"score_gpt":0.23123044385793287,"score_spread":0.21742271943698677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088550661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99810904,0.0004559238,0.00015768279,0.000084107516,0.000058806854,0.00011052196,0.0007600649,0.000013500192,0.00025032664],"genre_scores_gemma":[0.9960866,0.00021997989,0.001869067,0.00011542473,0.00012833944,0.0000027375565,0.0013648466,0.000025300935,0.00018772452],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985172,0.0000922976,0.00039842728,0.00045758914,0.000275074,0.0002594024],"domain_scores_gemma":[0.99874896,0.00007449638,0.00022994586,0.0005929381,0.00018762646,0.00016601902],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014945051,0.00024623613,0.00035211234,0.000012870297,0.000099413206,0.0000106319785,0.0004593365,0.00036719747,0.001208806],"category_scores_gemma":[0.00007569155,0.00019192277,0.00024870975,0.0001753878,0.00040177425,0.000005888824,0.000104342085,0.00019331282,0.000010846362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012292867,0.00021134633,0.00044667083,0.000017447495,0.00017066502,8.221952e-7,0.000079768295,0.000015558027,0.977386,0.000004992641,0.021490641,0.00005317731],"study_design_scores_gemma":[0.00035316788,0.00015288152,0.00010174722,0.00002227771,0.000036383342,0.0000024584328,0.00035126475,0.00013128684,0.9962502,0.000012167783,0.0023649202,0.0002212103],"about_ca_topic_score_codex":0.00029958008,"about_ca_topic_score_gemma":0.0000033825334,"teacher_disagreement_score":0.01912572,"about_ca_system_score_codex":0.000011766824,"about_ca_system_score_gemma":0.00009125656,"threshold_uncertainty_score":0.99970424},"labels":[],"label_agreement":null},{"id":"W2088607363","doi":"10.1038/nchembio0909-608","title":"A division of labor: asymmetric roles for GPCR subunits in receptor dimers","year":2009,"lang":"en","type":"letter","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"G protein-coupled receptor; Receptor; Signal transduction; Cell biology; Biology; Protein subunit; Computational biology; Biochemistry; Gene","score_opus":0.006535424637500172,"score_gpt":0.25990395426474194,"score_spread":0.25336852962724177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088607363","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7745212,0.059652083,0.0017436317,0.15371002,0.0035498359,0.0028177632,0.0026875297,0.000094033414,0.0012239222],"genre_scores_gemma":[0.69462925,0.0018816185,0.007873864,0.26479587,0.0061822566,0.00015017332,0.02369496,0.00017913789,0.0006128936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99800545,0.00010684213,0.00047507713,0.00075722754,0.00014225146,0.0005131614],"domain_scores_gemma":[0.99894166,0.00014883828,0.00026953145,0.00036903302,0.0002123459,0.000058562662],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00025562462,0.00038783462,0.0006388526,0.000254805,0.000025262634,0.000009153797,0.0005169105,0.005996402,0.00003833624],"category_scores_gemma":[0.0006386298,0.0003331666,0.0002882203,0.00033392716,0.00009343802,0.0000023497594,0.00011803413,0.001695759,0.0000031309798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009743493,0.00003826474,0.00010879084,0.00006532307,0.00004894604,0.0000019557724,0.0000067724045,7.6435754e-7,0.81258476,0.000061408486,0.17946538,0.0075202165],"study_design_scores_gemma":[0.0004351314,0.00027981683,0.000010952596,0.000044102726,0.000016364576,0.0000018632389,0.0000038983203,0.0000037732796,0.5691612,0.0004036211,0.42939848,0.00024083353],"about_ca_topic_score_codex":0.000006858762,"about_ca_topic_score_gemma":0.0000029083724,"teacher_disagreement_score":0.2499331,"about_ca_system_score_codex":0.00003743909,"about_ca_system_score_gemma":0.00008515354,"threshold_uncertainty_score":0.999912},"labels":[],"label_agreement":null},{"id":"W2088736807","doi":"10.1159/000127266","title":"Dissociated Adult Rat Subfornical Organ Neurons Maintain Membrane Properties and Angiotensin Responsiveness for up to 6 Days","year":2008,"lang":"en","type":"article","venue":"Neuroendocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Subfornical organ; Tetrodotoxin; Membrane potential; Electrophysiology; Internal medicine; Endocrinology; Angiotensin II; Current clamp; Patch clamp; Reversal potential; Chemistry; Voltage clamp; Sodium channel; Biophysics; Neuroscience; In vivo; Sodium; Medicine; Biology; Receptor","score_opus":0.028949851197017217,"score_gpt":0.24319282749230678,"score_spread":0.21424297629528957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2088736807","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99456584,0.00020461614,0.0009230989,0.0032353224,0.00049579877,0.0004952462,0.000025047128,0.000039744788,0.000015291125],"genre_scores_gemma":[0.9952872,0.0006372619,0.00047331915,0.0020796242,0.00016567779,0.00006907866,0.000049177495,0.000052702653,0.0011859707],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99837136,0.00017737588,0.0002459842,0.0005754046,0.0000943455,0.00053555483],"domain_scores_gemma":[0.9992408,0.000047392703,0.000058464775,0.0002918548,0.00020774084,0.0001537427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000026349897,0.00022182851,0.00028138273,0.000075448384,0.00025353167,0.000017999351,0.0001798576,0.00010186153,0.000019405777],"category_scores_gemma":[0.000614996,0.00020097342,0.00009237464,0.00009647834,0.00013872645,0.000005036002,0.00017972657,0.00012779479,0.000007595862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009718071,0.00002901183,0.0006390335,0.000012972254,0.000026579039,0.000080305384,0.000077467805,0.000031142383,0.9954701,0.0005636219,0.0016573163,0.00044065752],"study_design_scores_gemma":[0.0011305144,0.0012223503,0.0015614093,0.000009970803,0.000023279325,0.0007298338,0.0000984958,0.00010598716,0.96522295,0.000052538395,0.029587278,0.00025539],"about_ca_topic_score_codex":0.000019325858,"about_ca_topic_score_gemma":0.000036523496,"teacher_disagreement_score":0.030247133,"about_ca_system_score_codex":0.000011761183,"about_ca_system_score_gemma":0.00007415154,"threshold_uncertainty_score":0.8195458},"labels":[],"label_agreement":null},{"id":"W2089027834","doi":"10.1160/th13-02-0123","title":"Simultaneous measurement of ATP release and LTA does not potentiate platelet aggregation to epinephrine","year":2013,"lang":"en","type":"letter","venue":"Thrombosis and Haemostasis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; British Heart Foundation; Wellcome Trust","keywords":"Epinephrine; Platelet aggregation; Platelet; Medicine; Pharmacology; Chemistry; Internal medicine","score_opus":0.030067108575297315,"score_gpt":0.2567707959284926,"score_spread":0.2267036873531953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089027834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9268823,0.0014999207,0.0011999193,0.068583764,0.00030510285,0.0008811493,0.00055463944,0.000023545796,0.0000696557],"genre_scores_gemma":[0.8726164,0.008068931,0.0046952404,0.11120347,0.0014454089,0.000088925495,0.00095182966,0.00015564685,0.0007741434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99821687,0.00006979511,0.0004101668,0.00060220435,0.0003837152,0.00031722448],"domain_scores_gemma":[0.99895346,0.00002802787,0.00023872212,0.0003735752,0.00028598018,0.00012024776],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021995384,0.00036204566,0.0005136969,0.00009095543,0.00011057975,0.00006882858,0.00015073697,0.0004987056,0.00016505693],"category_scores_gemma":[0.00010215552,0.00028292468,0.00010993774,0.00006355421,0.00006980928,0.000006638959,0.0001772735,0.00023611056,0.00000682436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009311271,0.000041560066,0.00003367604,0.000402761,0.00046490398,0.000016941996,0.00015111086,0.00004934465,0.8321121,0.00001068255,0.092036664,0.07458716],"study_design_scores_gemma":[0.00052636827,0.00036864885,0.00007393221,0.00020594694,0.00015144351,0.000009219873,0.000039072715,0.00010099234,0.77280027,0.000052709634,0.22522776,0.00044361968],"about_ca_topic_score_codex":0.0002364092,"about_ca_topic_score_gemma":0.000023232393,"teacher_disagreement_score":0.13319108,"about_ca_system_score_codex":0.000019822482,"about_ca_system_score_gemma":0.000034883156,"threshold_uncertainty_score":0.9999623},"labels":[],"label_agreement":null},{"id":"W2089587204","doi":"10.1139/y10-078","title":"The influence of affinity, efficacy, and slope factor on the estimates obtained by the receptorial responsiveness method (RRM): a computer simulation study","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Hungarian Scientific Research Fund","keywords":"Agonist; Chemistry; Receptor; Reliability (semiconductor); Chromatography; Biophysics; Biological system; Biology; Biochemistry; Thermodynamics; Physics","score_opus":0.01339035010257182,"score_gpt":0.30799316367176466,"score_spread":0.2946028135691928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089587204","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977832,0.00016892311,0.00015054044,0.0007242505,0.000932704,0.0002222685,0.000013433926,9.2263616e-7,0.0000037805319],"genre_scores_gemma":[0.99900967,0.00003858311,0.000113704045,0.00039978718,0.0004152691,0.0000050558383,0.0000023920973,0.000007067895,0.000008456051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99883664,0.00059024617,0.0002193979,0.00013490416,0.000052571544,0.00016623901],"domain_scores_gemma":[0.9981784,0.0012189595,0.00020816627,0.000111862304,0.00017568095,0.00010692308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074256933,0.0001099405,0.00016794135,0.00003229366,0.00037579518,0.000019897327,0.00024956095,0.00011346549,0.0000979714],"category_scores_gemma":[0.00021078736,0.000056142213,0.00003661864,0.000050104114,0.00028561533,0.0000056469307,0.000040370116,0.0003192339,3.7217094e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050286955,0.000024409235,0.0002500716,0.0000036093682,0.00011820327,0.000001597327,0.0003661614,0.0035356733,0.9930055,0.000091733215,0.00054979534,0.001550386],"study_design_scores_gemma":[0.0019857187,0.0031366164,0.020461582,0.000010789382,0.00011352324,0.000038886363,0.00030369326,0.0010886852,0.9580851,0.0009117387,0.013681456,0.00018220334],"about_ca_topic_score_codex":0.000094623145,"about_ca_topic_score_gemma":0.00031560412,"teacher_disagreement_score":0.034920383,"about_ca_system_score_codex":0.000005489353,"about_ca_system_score_gemma":0.00020055899,"threshold_uncertainty_score":0.28903508},"labels":[],"label_agreement":null},{"id":"W2089749430","doi":"10.1021/pr801008c","title":"A Carboxy-Terminal Affinity Tag for the Purification and Mass Spectrometric Characterization of Integral Membrane Proteins","year":2009,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Integral membrane protein; Membrane protein; Biochemistry; G protein-coupled receptor; Chemistry; ATP-binding cassette transporter; Peptide; Trypsin; Biology; Membrane; Enzyme; Receptor; Transporter; Gene","score_opus":0.04270834688031386,"score_gpt":0.33502857762186394,"score_spread":0.2923202307415501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089749430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9665461,0.0003575305,0.031540718,0.000698929,0.000040694835,0.0007806967,0.0000072700527,0.0000011749553,0.000026892625],"genre_scores_gemma":[0.99440026,0.00046433913,0.0046292073,0.000009394739,0.00033598382,0.000028964225,0.000007751222,0.0000076178976,0.000116451185],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989513,0.00012750535,0.0002885584,0.00011784744,0.0003361023,0.00017867541],"domain_scores_gemma":[0.99896777,0.00003745351,0.00023077897,0.0001348997,0.00057126913,0.000057822144],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002183998,0.00007047979,0.00014215447,0.00022461878,0.00009883648,0.000043681735,0.0002023582,0.00008432034,0.000015923839],"category_scores_gemma":[0.0004192522,0.000045927216,0.00007620519,0.00027893952,0.00005351824,0.000011593672,0.00002133135,0.00022465418,2.4748203e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031261225,0.000049478465,0.00004874551,0.000039169798,0.000022694989,0.0000013306645,0.00004807411,0.0000023361897,0.9940656,0.00013230892,0.000008239421,0.0052694525],"study_design_scores_gemma":[0.00039065199,0.0021407972,0.0025802043,0.00003696754,0.0000107607975,0.00003427177,0.0000649095,0.00024789773,0.99333066,0.000521201,0.00059183926,0.00004982604],"about_ca_topic_score_codex":0.0000036025733,"about_ca_topic_score_gemma":5.662508e-7,"teacher_disagreement_score":0.027854195,"about_ca_system_score_codex":0.000020913849,"about_ca_system_score_gemma":0.00012524523,"threshold_uncertainty_score":0.18728575},"labels":[],"label_agreement":null},{"id":"W2089948844","doi":"10.1016/j.cardfail.2006.06.142","title":"C-KIT Receptor Maintains Cardiac Function in Aging Mice Post MI","year":2006,"lang":"en","type":"article","venue":"Journal of Cardiac Failure","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; Heart and Stroke Foundation; University of Toronto","funders":"","keywords":"Medicine; Myocardial infarction; Ventricular remodeling; Internal medicine; Cardiology; Cardiac function curve; Progenitor cell; Bone marrow; Heart failure; Receptor; Myocyte; Stem cell; Cell biology; Biology","score_opus":0.0034285118847633077,"score_gpt":0.2025560956841332,"score_spread":0.1991275837993699,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089948844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925392,0.003844938,0.00096970494,0.0004948942,0.0013871737,0.00010062048,0.000022978158,0.000005421176,0.00063505874],"genre_scores_gemma":[0.995065,0.0002475581,0.0019004237,0.00012193629,0.0022521263,0.0000035149192,0.000061151986,0.000029794655,0.00031851395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998755,0.00014434393,0.00040947436,0.0001875848,0.00024586948,0.000257731],"domain_scores_gemma":[0.9992662,0.000017153903,0.00023909927,0.00015325652,0.00024647973,0.00007782176],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000616751,0.00016005684,0.00030653898,0.00012500725,0.00005711165,0.00004820945,0.00013037796,0.0001903953,0.0000673414],"category_scores_gemma":[0.00004471131,0.0001492469,0.00044433464,0.00012982705,0.00002213909,0.000016194546,0.000039018465,0.00024071954,0.000009574627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009036874,0.000024204252,0.0038569712,0.000012187477,0.000087452594,0.00000415143,0.00003211485,0.0003585017,0.9783999,0.00012151143,0.01566501,0.001347674],"study_design_scores_gemma":[0.00053189404,0.00040093766,0.0060543823,0.00007712273,0.00008186162,0.000024386478,0.0008534614,0.000004555822,0.54840505,0.00017650586,0.44310603,0.00028379812],"about_ca_topic_score_codex":0.000051695253,"about_ca_topic_score_gemma":0.000019942416,"teacher_disagreement_score":0.4299948,"about_ca_system_score_codex":0.000051021307,"about_ca_system_score_gemma":0.00010096771,"threshold_uncertainty_score":0.6086112},"labels":[],"label_agreement":null},{"id":"W2090798921","doi":"10.1210/me.2003-0488","title":"Down-Regulation of Inositol 1,4,5-Trisphosphate Receptor in Cells Stably Expressing the Constitutively Active Angiotensin II N111G-AT1 Receptor","year":2004,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Biology; Inositol trisphosphate receptor; Phospholipase C; Gq alpha subunit; Receptor; Angiotensin II; Inositol; Inositol trisphosphate; Inositol phosphate; Cell biology; Intracellular; Extracellular; Purinergic receptor; HEK 293 cells; Signal transduction; G protein; Biochemistry","score_opus":0.0077406267147895865,"score_gpt":0.22688083037439843,"score_spread":0.21914020365960885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090798921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98354274,0.0011759412,0.013299432,0.0005513068,0.0005551529,0.00049471826,0.000050688803,0.000021297214,0.00030870672],"genre_scores_gemma":[0.99326557,0.00018484797,0.0059955195,0.00021508124,0.00008621418,0.000041457053,0.000099325014,0.00003551758,0.000076446755],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979961,0.00021097939,0.00046476276,0.00055999216,0.00020889447,0.00055928726],"domain_scores_gemma":[0.9990143,0.000025896496,0.0002639477,0.00044826174,0.00017298062,0.00007459822],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015620438,0.00029622525,0.00035666607,0.00012735279,0.00017960859,0.000021558328,0.0003270362,0.00025064638,0.000094118936],"category_scores_gemma":[0.00008662289,0.00025660757,0.00017196259,0.00024228237,0.00032055302,0.000015707348,0.00025834105,0.0002458196,0.000014684541],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023769075,0.000107813474,0.0000611537,0.000009635343,0.00008106678,0.000014949417,0.00024306845,0.0030143233,0.98912466,0.0035628702,0.00023845436,0.003304317],"study_design_scores_gemma":[0.0014171916,0.00031912315,0.0002910892,0.000052832485,0.000024793271,0.000021662308,0.00023212013,0.000023578268,0.9848592,0.00046686394,0.012023402,0.00026809605],"about_ca_topic_score_codex":0.00021217561,"about_ca_topic_score_gemma":0.000034182827,"teacher_disagreement_score":0.0117849475,"about_ca_system_score_codex":0.00007291712,"about_ca_system_score_gemma":0.00018751841,"threshold_uncertainty_score":0.9999886},"labels":[],"label_agreement":null},{"id":"W2091082924","doi":"10.1074/jbc.m109.088625","title":"Dopamine D1-D2 Receptor Heteromer-mediated Calcium Release Is Desensitized by D1 Receptor Occupancy with or without Signal Activation","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse","keywords":"Dopamine receptor D2; Chemistry; Agonist; Cell biology; G protein-coupled receptor; Receptor; Dopamine receptor; Dopamine receptor D1; Biophysics; Endogenous agonist; Desensitization (medicine); Biochemistry; Biology","score_opus":0.016817694573742884,"score_gpt":0.2555156626050982,"score_spread":0.23869796803135535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091082924","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968033,0.00014372214,0.0022260507,0.0003111619,0.00018002724,0.00014224807,0.000075772616,0.000020552987,0.00009720905],"genre_scores_gemma":[0.9925647,0.00016710765,0.0047852173,0.00048241395,0.0009316301,0.000010078642,0.0003175723,0.000036492154,0.0007047995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981119,0.00008086176,0.000627399,0.00044455755,0.00033148096,0.00040380406],"domain_scores_gemma":[0.998202,0.00006913406,0.0006529617,0.0002739948,0.00042030396,0.00038156228],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00037818175,0.0003628203,0.0005154056,0.00003400412,0.00011384856,0.00005336468,0.00032731748,0.00064819324,0.0027375822],"category_scores_gemma":[0.00047142993,0.0002217787,0.00021088308,0.00015832602,0.0001749518,0.00001816359,0.000072482624,0.0006912155,0.000013187678],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029881974,0.00019367131,0.001911876,0.000024327708,0.0001154131,0.000011106388,0.00001815987,0.0000018908551,0.98779285,4.999297e-7,0.0061924695,0.0007495614],"study_design_scores_gemma":[0.0018284916,0.0011620956,0.0000616631,0.000060870327,0.00002689172,0.00016642953,0.000106011066,0.000038716073,0.975021,0.000008099489,0.02116438,0.0003553403],"about_ca_topic_score_codex":0.0000062869767,"about_ca_topic_score_gemma":9.87541e-7,"teacher_disagreement_score":0.01497191,"about_ca_system_score_codex":0.000035223537,"about_ca_system_score_gemma":0.0001932888,"threshold_uncertainty_score":0.9981741},"labels":[],"label_agreement":null},{"id":"W2091742123","doi":"10.1074/jbc.m605012200","title":"Seven Transmembrane Receptor Core Signaling Complexes Are Assembled Prior to Plasma Membrane Trafficking","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; Université de Montréal; McGill University","funders":"","keywords":"Cell biology; Endoplasmic reticulum; Receptor; G protein-coupled receptor; Internalization; Signal transduction; Bimolecular fluorescence complementation; Chemistry; Förster resonance energy transfer; Biology; Biochemistry","score_opus":0.02512379270912369,"score_gpt":0.2529492951666412,"score_spread":0.22782550245751754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091742123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963871,0.00045763567,0.0023099238,0.00022098908,0.00017277026,0.00012967069,0.000024207544,0.000020372958,0.00027733165],"genre_scores_gemma":[0.99302787,0.00008064049,0.0051153023,0.00015673628,0.0013155597,0.000005854104,0.000060313185,0.000028767774,0.00020895523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981134,0.000059007918,0.0007590236,0.00037877192,0.00028714453,0.00040266532],"domain_scores_gemma":[0.99878246,0.0000647028,0.0004949933,0.0001896142,0.00023766521,0.0002305684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005079538,0.0003030639,0.00052901654,0.00004347625,0.00013005502,0.00007391399,0.0005254296,0.00040398713,0.00043055508],"category_scores_gemma":[0.00015462097,0.00023166218,0.0003653378,0.0001560617,0.00004857217,0.0000102157765,0.00007768761,0.00031359948,0.000005839053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004436135,0.00013755339,0.00034169527,0.00005278321,0.0000649205,0.000027021415,0.00002546963,0.0025748725,0.99488497,0.000009767689,0.0007016797,0.0007356295],"study_design_scores_gemma":[0.0009036,0.00034851214,0.00016227031,0.00012284271,0.000027751255,0.00015666753,0.0002300282,0.00005236888,0.9882161,0.00006365147,0.009393176,0.00032304018],"about_ca_topic_score_codex":0.000003822427,"about_ca_topic_score_gemma":0.0000022312822,"teacher_disagreement_score":0.008691496,"about_ca_system_score_codex":0.00004032535,"about_ca_system_score_gemma":0.00007664004,"threshold_uncertainty_score":0.94469094},"labels":[],"label_agreement":null},{"id":"W2092116730","doi":"10.3389/fendo.2014.00068","title":"Allosteric and Biased G Protein-Coupled Receptor Signaling Regulation: Potentials for New Therapeutics","year":2014,"lang":"en","type":"review","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University","keywords":"Allosteric regulation; G protein-coupled receptor; Functional selectivity; Signal transduction; Receptor; G protein; Drug discovery; Cell biology; Biology; Cell signaling; Chemistry; Computational biology; Biochemistry","score_opus":0.03345765983320658,"score_gpt":0.29424745941889374,"score_spread":0.26078979958568715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092116730","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00031104928,0.8559425,0.1409265,0.00005021606,0.0011198069,0.0015864549,0.00002282524,0.000019667805,0.000020970792],"genre_scores_gemma":[0.00015608873,0.9461307,0.050269045,0.000111033834,0.00092753913,0.00034376685,0.00060815853,0.00011157683,0.0013421116],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975973,0.00023952643,0.0007116619,0.00077576493,0.00010739189,0.0005683479],"domain_scores_gemma":[0.9989828,0.0000394777,0.00041259153,0.00040611878,0.00006014118,0.000098886834],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024873574,0.00047435216,0.0013681138,0.00023028643,0.000086931075,0.000043749733,0.00031987706,0.00061422004,0.000050849532],"category_scores_gemma":[0.000074401876,0.00043807033,0.00033143425,0.00012522413,0.00008259831,0.000004978279,0.000116441035,0.00021489714,0.000003860575],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011519585,0.00003284569,0.0000072165517,0.0024249945,0.00044142455,0.0000031871855,0.000025986155,0.000018704277,0.039655406,0.00019148788,0.0024269691,0.9546566],"study_design_scores_gemma":[0.0008366147,0.00035853268,4.1695506e-7,0.0008390127,0.00024786292,0.000027841019,0.000022107562,0.00013090878,0.0064224987,0.00058677985,0.99004954,0.00047786592],"about_ca_topic_score_codex":0.000009238831,"about_ca_topic_score_gemma":0.0000035136154,"teacher_disagreement_score":0.9876226,"about_ca_system_score_codex":0.00004357361,"about_ca_system_score_gemma":0.00020650543,"threshold_uncertainty_score":0.9998071},"labels":[],"label_agreement":null},{"id":"W2092247923","doi":"10.1074/jbc.m114.568147","title":"Differential Regulation of Endosomal GPCR/β-Arrestin Complexes and Trafficking by MAPK","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University","keywords":"Arrestin; Endosome; G protein-coupled receptor; Cell biology; Biology; Receptor; Signal transduction; MAPK/ERK pathway; Endocytosis; G protein; Intracellular; Biochemistry","score_opus":0.012278107733249338,"score_gpt":0.2237986811387707,"score_spread":0.21152057340552136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092247923","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939571,0.00038551114,0.005386857,0.00003088643,0.000060119517,0.00002589162,0.0000074314785,0.0000030936064,0.0001431258],"genre_scores_gemma":[0.9985992,0.00006940683,0.0008856746,0.000019822613,0.00034290468,6.220818e-7,0.000032588032,0.0000061657724,0.000043615808],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924403,0.000044956418,0.00033929697,0.00014012841,0.00010911677,0.00012245613],"domain_scores_gemma":[0.9994261,0.000032972697,0.00030929942,0.00008086877,0.000073340816,0.000077399505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016550081,0.000108881395,0.00022162334,0.000010744397,0.000036586374,0.000013347201,0.00012190862,0.00018094567,0.00014944002],"category_scores_gemma":[0.00013738687,0.000078693454,0.000099261095,0.000024370076,0.00007355189,0.0000030296023,0.000047221394,0.00010719425,1.8680615e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000096186806,0.00004144364,0.001507449,0.000021236277,0.00002258891,5.094141e-7,0.000007329556,0.000018170433,0.9960147,0.000022041944,0.00019583691,0.0020524713],"study_design_scores_gemma":[0.00047011458,0.00029021484,0.0021078745,0.000028375318,0.000012304054,0.00004304324,0.000026513213,0.0001100837,0.99501747,0.00017659122,0.0016248456,0.00009257053],"about_ca_topic_score_codex":8.5662623e-7,"about_ca_topic_score_gemma":1.0985494e-7,"teacher_disagreement_score":0.004642116,"about_ca_system_score_codex":0.000005117853,"about_ca_system_score_gemma":0.000011850628,"threshold_uncertainty_score":0.32090262},"labels":[],"label_agreement":null},{"id":"W2092405607","doi":"10.1016/j.bpj.2012.11.171","title":"Functional Assessment of Crystallization-Optimized G Protein-Coupled Receptors using Ion Channel-Coupled Receptors","year":2013,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Ion channel; Receptor; Chemistry; Class C GPCR; Biophysics; Ligand-gated ion channel; Agonist; Ligand (biochemistry); Biochemistry; Biology; Metabotropic receptor","score_opus":0.015797567278164976,"score_gpt":0.25257585192953785,"score_spread":0.23677828465137288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092405607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7763842,0.000031619747,0.22230862,0.00007953248,0.0007846755,0.00034807855,0.0000029038251,0.000011690012,0.000048716745],"genre_scores_gemma":[0.9820922,0.000059252736,0.015989188,0.00005362558,0.0013437857,0.00003524316,0.0000843201,0.000044934946,0.00029747494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819386,0.00012357041,0.0005456957,0.000334698,0.00045860236,0.00034357337],"domain_scores_gemma":[0.9986427,0.000016036574,0.00043238775,0.00020349104,0.0004932831,0.00021209307],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029451423,0.00025684238,0.00033133678,0.000096457705,0.00022835436,0.00009431151,0.00019567048,0.00020524632,0.0016484628],"category_scores_gemma":[0.000062048515,0.0002176801,0.0002916912,0.00019094686,0.000079710095,0.000030216577,0.00008223974,0.00023893043,0.000011930133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008253097,0.0001736266,0.00004186252,0.00001576196,0.00011287865,8.9924845e-7,0.000018491635,0.0055484273,0.99333906,0.000119629076,0.00033400647,0.00021282074],"study_design_scores_gemma":[0.0015271611,0.0005894705,0.00027017528,0.000085548236,0.000047407422,0.000027318529,0.00015901057,0.085809305,0.91047144,0.00029879858,0.00033519778,0.00037915696],"about_ca_topic_score_codex":0.00003431692,"about_ca_topic_score_gemma":6.024054e-7,"teacher_disagreement_score":0.20631944,"about_ca_system_score_codex":0.00006778949,"about_ca_system_score_gemma":0.00019236692,"threshold_uncertainty_score":0.9992642},"labels":[],"label_agreement":null},{"id":"W2092436590","doi":"10.1016/j.bbamcr.2014.01.002","title":"Somatostatin receptor-2 negatively regulates β-adrenergic receptor mediated Ca2+ dependent signaling pathways in H9c2 cells","year":2014,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC; Health Research","keywords":"Somatostatin receptor 2; Agonist; NFAT; Endocrinology; Internal medicine; Signal transduction; Cell biology; Chemistry; Receptor; Inverse agonist; Somatostatin receptor; Protein kinase C; Biology; Calcineurin; Medicine","score_opus":0.021752946442085044,"score_gpt":0.27154712973883216,"score_spread":0.24979418329674713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092436590","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956084,0.00037607516,0.00094837847,0.000366445,0.00025777525,0.0008245245,0.00011090285,0.00006937599,0.001438141],"genre_scores_gemma":[0.9928805,0.0005473964,0.004287357,0.00030212148,0.00029742246,0.00015734026,0.00091227546,0.00020537153,0.00041019876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99246997,0.0020511786,0.00088901405,0.0016861735,0.0013788333,0.0015248146],"domain_scores_gemma":[0.99726266,0.00031979583,0.0003330925,0.0010949147,0.00048435605,0.0005051703],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0024838012,0.00070858654,0.00065774436,0.00050104945,0.00033242317,0.0002700852,0.0011618733,0.0006420214,0.00023528149],"category_scores_gemma":[0.00036535526,0.00070098724,0.00035201423,0.0009418242,0.00033629657,0.000032261552,0.000669662,0.00094736187,0.00021427129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002741299,0.0003762419,0.0000048835886,0.000093047915,0.00008089937,0.000016350828,0.00040790686,0.0002922585,0.99665326,0.00038975448,0.00089426315,0.0005170013],"study_design_scores_gemma":[0.0013985669,0.0008580262,0.000027447493,0.00012793687,0.000017597333,0.0000024884478,0.00042734813,0.00081516965,0.99284726,0.00051058544,0.002160012,0.0008075466],"about_ca_topic_score_codex":0.00019531796,"about_ca_topic_score_gemma":0.000023438719,"teacher_disagreement_score":0.0047926847,"about_ca_system_score_codex":0.00013698002,"about_ca_system_score_gemma":0.00044082286,"threshold_uncertainty_score":0.99954414},"labels":[],"label_agreement":null},{"id":"W2092459005","doi":"10.1371/journal.pone.0085937","title":"Inverse Agonism of SQ 29,548 and Ramatroban on Thromboxane A2 Receptor","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba; Research Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Manitoba Medical Service Foundation; National Heart, Lung, and Blood Institute; Manitoba Health Research Council","keywords":"Inverse agonist; G protein-coupled receptor; Receptor; Pathophysiology; Platelet; Thromboxane; Pharmacology; Internal medicine; Platelet activation; Endocrinology; Agonist; Chemistry; Medicine","score_opus":0.02187039893871683,"score_gpt":0.2091372841577954,"score_spread":0.18726688521907855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092459005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99796915,0.00011559342,0.0003093151,0.00011723506,0.0000608768,0.000118497075,0.000010412255,0.000010930972,0.001287975],"genre_scores_gemma":[0.9934761,0.00024624984,0.005216129,0.00026258206,0.00021318848,0.000008101689,0.000052873635,0.000021350868,0.00050344557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924797,0.000050735653,0.0001564515,0.00024260647,0.00014613147,0.00015608096],"domain_scores_gemma":[0.9995316,0.000014494068,0.00007913321,0.0002450843,0.000053170716,0.000076477794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016914247,0.00011720724,0.00019996036,0.000028727738,0.000045878107,0.000012543157,0.00009772463,0.0001276737,0.00016185197],"category_scores_gemma":[0.00008017947,0.000108647175,0.000046588477,0.00003479378,0.000050815248,0.0000025700954,0.000056770627,0.00007336192,0.000022757602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004267742,0.00021343252,0.00023429778,0.00004914349,0.00008478741,1.8810606e-7,0.00004877413,0.00000517483,0.99767995,0.00055540266,0.0004210953,0.00066510716],"study_design_scores_gemma":[0.00043589986,0.000711717,0.00011444727,0.000069471236,0.000033708962,5.870646e-7,0.000033838365,0.00012419019,0.99604064,0.0002602697,0.0020446945,0.00013053583],"about_ca_topic_score_codex":0.00001119216,"about_ca_topic_score_gemma":0.0000052651253,"teacher_disagreement_score":0.0049068136,"about_ca_system_score_codex":0.0000055878218,"about_ca_system_score_gemma":0.000014788913,"threshold_uncertainty_score":0.4430503},"labels":[],"label_agreement":null},{"id":"W2092665404","doi":"10.1371/journal.pone.0070736","title":"Effects of the Dopamine D2 Allosteric Modulator, PAOPA, on the Expression of GRK2, Arrestin-3, ERK1/2, and on Receptor Internalization","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Internalization; Arrestin; Allosteric modulator; Allosteric regulation; Dopamine receptor D2; Beta adrenergic receptor kinase; Chemistry; Cell biology; Receptor; G protein-coupled receptor; Biology; Biochemistry","score_opus":0.012191849018849767,"score_gpt":0.18772028362524737,"score_spread":0.1755284346063976,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092665404","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987702,0.00024319028,0.00030697277,0.00011874674,0.00007122868,0.0003823412,0.0000032873993,0.0000037821196,0.00010028637],"genre_scores_gemma":[0.99907064,0.00013370698,0.00028758738,0.00014130988,0.000079706195,0.000034149947,0.000007927436,0.000014635136,0.00023031906],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993012,0.00009698231,0.00015976283,0.00016581317,0.00018358596,0.00009267043],"domain_scores_gemma":[0.9994599,0.00005470137,0.0001452037,0.00024374474,0.00006723248,0.000029185034],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000091449234,0.00010175495,0.00012856696,0.00001776277,0.000041114097,0.000008057326,0.00015094328,0.000071582625,0.000072406874],"category_scores_gemma":[0.00016506348,0.000056492507,0.000041807052,0.00004593229,0.00004239557,0.0000033291892,0.0000877619,0.000064740474,0.000004461454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042810294,0.00022324134,0.00063183554,0.0000788995,0.000034433182,7.182024e-8,0.000038268503,0.000014414356,0.9981826,0.00007935815,0.00017603942,0.00049802824],"study_design_scores_gemma":[0.0002442372,0.0004044494,0.001446456,0.00047269423,0.00002021075,2.3971717e-7,0.000012200512,0.00018650801,0.996948,0.00014587214,0.0000548183,0.00006430434],"about_ca_topic_score_codex":0.000012199703,"about_ca_topic_score_gemma":6.7093094e-7,"teacher_disagreement_score":0.0012345902,"about_ca_system_score_codex":0.000004940641,"about_ca_system_score_gemma":0.000007733353,"threshold_uncertainty_score":0.23036976},"labels":[],"label_agreement":null},{"id":"W2092933199","doi":"10.3389/fnbeh.2014.00199","title":"Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression","year":2014,"lang":"en","type":"review","venue":"Frontiers in Behavioral Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":320,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Canadian Institutes of Health Research","keywords":"Neuroscience; 5-HT1A receptor; Serotonin; Prefrontal cortex; Psychology; Serotonergic; Amygdala; 5-HT receptor; Biology; Receptor; Genetics; Cognition","score_opus":0.013729098446254083,"score_gpt":0.2825463848193412,"score_spread":0.2688172863730871,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092933199","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5245638,0.47380897,0.00042884465,8.1376356e-7,0.0005701772,0.00056094397,0.00005010183,0.000006968653,0.000009347393],"genre_scores_gemma":[0.29454836,0.7025099,0.0025934428,0.000022408118,0.00006723292,0.00009971786,0.000074955184,0.000050364662,0.000033670887],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975888,0.00030645062,0.00055827457,0.0009336766,0.00023939354,0.00037339932],"domain_scores_gemma":[0.9992053,0.000016116732,0.00025217517,0.00034028856,0.000034190678,0.00015193914],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036699045,0.00036068386,0.0008362108,0.00015656553,0.00007754427,0.00003953754,0.0003528399,0.00045616753,0.0000061518244],"category_scores_gemma":[0.0001166202,0.00031277537,0.00011794986,0.00016434817,0.00026749645,0.00002259593,0.0003539064,0.0004156365,3.3887164e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007844423,0.00014384276,0.013819181,0.0006460161,0.000002740896,0.0000039730426,0.000094906754,0.0000040379864,0.75065976,0.0000032825337,0.000023376611,0.23452045],"study_design_scores_gemma":[0.008956813,0.011357512,0.10175212,0.047812734,0.0016628576,0.0012165935,0.003097976,0.003889357,0.430824,0.00032845084,0.3781319,0.010969672],"about_ca_topic_score_codex":0.000034608343,"about_ca_topic_score_gemma":0.000005617809,"teacher_disagreement_score":0.37810853,"about_ca_system_score_codex":0.000031614374,"about_ca_system_score_gemma":0.00010061993,"threshold_uncertainty_score":0.9999324},"labels":[],"label_agreement":null},{"id":"W2093246724","doi":"10.1139/o04-128","title":"Inverse agonism: more than reverting constitutively active receptor signaling","year":2004,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Inverse agonist; Receptor; Functional selectivity; Cell biology; G protein-coupled receptor; Transmembrane protein; Signal transduction; Enzyme-linked receptor; Agonism; Biology; Allosteric regulation; Agonist; Pharmacology; Biochemistry; Political science","score_opus":0.020539285592601455,"score_gpt":0.2757625478922022,"score_spread":0.2552232622996008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093246724","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006318572,0.99078137,0.00023604602,0.000012919827,0.00038021887,0.00043548096,0.00040525358,0.00003502457,0.0013950957],"genre_scores_gemma":[0.00302937,0.9911483,0.0013584652,0.0000860653,0.0006991279,0.000084141386,0.002461685,0.00007067073,0.0010621613],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973502,0.00014549337,0.00062134006,0.0012075849,0.00010143886,0.0005739226],"domain_scores_gemma":[0.99863046,0.000049102455,0.00054749916,0.00044189222,0.000090286245,0.00024072891],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00025152607,0.0007453069,0.0011283112,0.00006702634,0.00025043415,0.000042695156,0.0003909888,0.0016066831,0.00013056508],"category_scores_gemma":[0.00010954412,0.0006585225,0.00048322472,0.00013800689,0.00043332423,0.0000054570096,0.00032024793,0.00049196597,0.000025401385],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053872787,0.00006853099,0.0000036050217,0.006004793,0.00027660248,0.000012416159,0.000056194658,0.0000028227118,0.8538161,0.00007902755,0.00023805934,0.13938797],"study_design_scores_gemma":[0.0002907508,0.0001153269,4.8015533e-8,0.0016977285,0.00018912902,0.00004242747,0.00014108304,6.926118e-7,0.44182613,0.00003167363,0.55509657,0.00056843396],"about_ca_topic_score_codex":0.000020916119,"about_ca_topic_score_gemma":9.693742e-7,"teacher_disagreement_score":0.5548585,"about_ca_system_score_codex":0.000084423096,"about_ca_system_score_gemma":0.0007141262,"threshold_uncertainty_score":0.99968946},"labels":[],"label_agreement":null},{"id":"W2093273780","doi":"10.1006/jmcc.2001.1381","title":"β -Adrenergic Stimulation of Rat Cardiac Fibroblasts Promotes Protein Synthesis via the Activation of Phosphatidylinositol 3-kinase","year":2001,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; Université de Montréal","funders":"","keywords":"MAPK/ERK pathway; Endocrinology; Protein kinase A; Internal medicine; Signal transduction; Kinase; Biology; Chemistry; Cell biology; Medicine","score_opus":0.006086452444990823,"score_gpt":0.20348229012280342,"score_spread":0.1973958376778126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093273780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.937047,0.002854752,0.05965714,0.000050876573,0.00012510076,0.00019798128,0.0000023820278,0.0000015846441,0.00006315278],"genre_scores_gemma":[0.9988646,0.00017996013,0.0007311975,0.000013377185,0.00015512384,0.0000076045512,0.000010707908,0.000015654809,0.000021774233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987657,0.00031136125,0.0004401859,0.00015564926,0.00018525655,0.0001418529],"domain_scores_gemma":[0.9989931,0.000035911893,0.0004632245,0.00020245151,0.00025433055,0.00005097905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005013003,0.00014017605,0.00039544248,0.000065016415,0.000048211263,0.000008120677,0.00013548454,0.00017093864,0.000010919938],"category_scores_gemma":[0.000112027024,0.00010155411,0.00029756883,0.00009241145,0.000087903114,0.000008644131,0.000047233,0.000103598744,1.9208393e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021931232,0.000024632636,0.00064991147,0.000033830307,0.00022252477,0.000014586199,0.000037745132,0.0032778776,0.9923706,0.00008718928,0.000018170222,0.0030436355],"study_design_scores_gemma":[0.00030962605,0.0005496663,0.00021165199,0.000059060785,0.00011413207,0.000054123928,0.000076043645,0.00017330471,0.9976812,0.00023207467,0.0004408257,0.00009831176],"about_ca_topic_score_codex":0.000008634417,"about_ca_topic_score_gemma":2.5020543e-7,"teacher_disagreement_score":0.06181757,"about_ca_system_score_codex":0.00000848349,"about_ca_system_score_gemma":0.000054370124,"threshold_uncertainty_score":0.41412565},"labels":[],"label_agreement":null},{"id":"W2093370075","doi":"10.1002/syn.20691","title":"Altered expression and alpha‐1 adrenergic receptor mediated activity of protein kinase C in the prefrontal cortex of rats with neonatal ventral hippocampus lesions","year":2009,"lang":"en","type":"article","venue":"Synapse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Prefrontal cortex; Internal medicine; Endocrinology; Protein kinase C; Hippocampus; Neuroscience; Receptor; Stimulation; Biology; Chemistry; Signal transduction; Medicine; Cell biology","score_opus":0.006737151853630178,"score_gpt":0.2208187663955675,"score_spread":0.2140816145419373,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093370075","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988001,0.0005390658,0.00023525298,0.000041529638,0.000028048129,0.0003025653,0.000029184119,0.0000034555817,0.000020809215],"genre_scores_gemma":[0.9991964,0.000050640887,0.0005884855,0.000016399688,0.000032812164,0.000016492611,0.00007616029,0.000007245808,0.000015365296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992475,0.000113509595,0.000154483,0.00020619773,0.0001294338,0.00014885784],"domain_scores_gemma":[0.99960613,0.000012291985,0.000120585646,0.00018583005,0.00003007618,0.00004511067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012572955,0.00011461385,0.00015532375,0.000029412864,0.00003375591,0.0000056885656,0.00011769926,0.00010132755,0.000025347694],"category_scores_gemma":[0.000030634095,0.000074995514,0.000037865822,0.00006543084,0.00006429035,0.00000718196,0.000029639727,0.00008462207,2.5900712e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054510613,0.000116341325,0.00011140618,0.000014301982,0.000010550943,0.0000052514642,0.00017152216,0.000010856376,0.99555045,0.000023560406,0.000017108918,0.0034235169],"study_design_scores_gemma":[0.0007333971,0.00091757317,0.005441442,0.0000856566,0.000007180354,0.000009803017,0.00014488479,0.000037358022,0.99240386,0.000077731886,0.00004880902,0.00009232434],"about_ca_topic_score_codex":0.000031305466,"about_ca_topic_score_gemma":0.000030783493,"teacher_disagreement_score":0.005330036,"about_ca_system_score_codex":0.000005993969,"about_ca_system_score_gemma":0.000048376016,"threshold_uncertainty_score":0.30582285},"labels":[],"label_agreement":null},{"id":"W2093541495","doi":"10.1002/syn.20673","title":"Glutamate agonists for treating schizophrenia have affinity for dopamine D2<sup>High</sup> and D3 receptors","year":2009,"lang":"en","type":"article","venue":"Synapse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Agonist; Dopamine receptor D2; Receptor; Dissociation constant; Glutamate receptor; Dopamine receptor D3; Dopamine; Chemistry; Dopamine receptor; Pharmacology; Internal medicine; Endocrinology; Biology; Biochemistry; Medicine","score_opus":0.008927393171067718,"score_gpt":0.2459233005529906,"score_spread":0.2369959073819229,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093541495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99201745,0.00049996906,0.0062669087,0.00028110226,0.00012297557,0.0005578515,0.00010185906,0.000030044006,0.000121816236],"genre_scores_gemma":[0.9808404,0.000105947925,0.017372692,0.00013726132,0.00046430586,0.00007764496,0.00037421574,0.000033219145,0.00059430796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998778,0.000036382018,0.00026280808,0.00046826288,0.00008379891,0.000370762],"domain_scores_gemma":[0.99939054,0.00004532635,0.00011176577,0.00023763454,0.00009516226,0.00011959816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024412297,0.00023730534,0.00026022788,0.000044591736,0.00024674166,0.00006605931,0.00013294262,0.00020914187,0.000034022123],"category_scores_gemma":[0.0001969116,0.00021742834,0.00013571224,0.000044338576,0.000043083408,0.0000077812665,0.000041209696,0.00007152091,0.0000023219147],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007519908,0.000076099655,0.000108969296,0.00005461475,0.000072519964,0.0000021773049,0.00010999347,0.00017314313,0.9718361,0.0011631009,0.00088543294,0.024765845],"study_design_scores_gemma":[0.00257905,0.0017404226,0.00015090076,0.00004199008,0.000059539056,0.000021593221,0.0001911622,0.001489222,0.9831442,0.0024785842,0.0076773646,0.00042595956],"about_ca_topic_score_codex":0.000015036697,"about_ca_topic_score_gemma":0.0000131259185,"teacher_disagreement_score":0.024339885,"about_ca_system_score_codex":0.000015791704,"about_ca_system_score_gemma":0.000040480812,"threshold_uncertainty_score":0.88664705},"labels":[],"label_agreement":null},{"id":"W2093593644","doi":"10.1016/s0167-4781(99)00241-9","title":"Cloning and characterization of additional members of the G protein-coupled receptor family","year":2000,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"National Institute of General Medical Sciences","keywords":"Pseudogene; Biology; Complementary DNA; Open reading frame; cDNA library; Genetics; Molecular biology; Subfamily; Sequence analysis; genomic DNA; G protein-coupled receptor; Peptide sequence; Receptor; Gene; Genome","score_opus":0.004209705856648312,"score_gpt":0.19626557596586827,"score_spread":0.19205587010921996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093593644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987851,0.00007187696,0.000031848216,0.00007582143,0.00006596333,0.00023649838,0.00068987964,0.000005818397,0.000037185782],"genre_scores_gemma":[0.9972182,0.00021778575,0.0012505704,0.00008490053,0.00016151297,0.000012255861,0.0009345105,0.00001918722,0.000101064135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909735,0.00006665711,0.00023425069,0.0003032703,0.00016398229,0.00013449414],"domain_scores_gemma":[0.99946326,0.000008896469,0.00020266332,0.00021854017,0.00005466104,0.000051969993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005253595,0.00017362199,0.00018521887,0.00002631983,0.000110754285,0.000017794648,0.00012869429,0.00015864872,0.00036207458],"category_scores_gemma":[0.000011626631,0.00012110959,0.000074224045,0.000079434074,0.00010872019,0.000013139768,0.000086096334,0.000086504355,2.5619397e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001546313,0.000018675282,0.000002591175,0.000031924403,0.000026838718,6.329998e-8,0.00012554787,0.0000039839456,0.99891955,0.00002189089,0.00013977966,0.00055449846],"study_design_scores_gemma":[0.0003005943,0.00012995242,0.0019799122,0.000113554306,0.000017441065,0.000002545097,0.000026367015,0.00006340497,0.99646723,0.00010741227,0.00064953684,0.00014205287],"about_ca_topic_score_codex":0.000007716217,"about_ca_topic_score_gemma":5.277257e-7,"teacher_disagreement_score":0.0024523484,"about_ca_system_score_codex":0.0000035922794,"about_ca_system_score_gemma":0.00003846416,"threshold_uncertainty_score":0.4938706},"labels":[],"label_agreement":null},{"id":"W209384339","doi":"10.71781/4713","title":"Signaling potential gender effect in a spontaneous reporting system : cardiac effects associated with the use of antibiotics","year":2008,"lang":"en","type":"dissertation","venue":"Open MIND","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Antibiotics; Medicine; Psychology; Internal medicine; Pharmacology; Biology; Microbiology","score_opus":0.02454831807521214,"score_gpt":0.2646536343336198,"score_spread":0.2401053162584077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W209384339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99786633,0.0002985294,0.00011730174,0.0000010584204,0.00031656295,0.0010083624,0.000022153194,0.0000013595609,0.0003683621],"genre_scores_gemma":[0.99718094,0.000023783416,0.0006164277,0.0000043683067,0.000082152845,0.0000052484716,0.0011728621,0.00005208772,0.0008621128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99806714,0.00033972057,0.0006191001,0.00045557812,0.00026491252,0.0002535316],"domain_scores_gemma":[0.99805754,0.00009379362,0.0013549773,0.00031230605,0.00013915425,0.000042224663],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079704606,0.0002805174,0.0006080278,0.00005470924,0.000111644105,0.00009627376,0.00026021845,0.00041305815,0.000013931731],"category_scores_gemma":[0.0003314336,0.0001980754,0.00017850021,0.00012278892,0.000022290422,0.000006030736,0.00006293237,0.00022064414,0.0000018284275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044889402,0.000036568486,0.0004932948,0.00017936977,0.0004099819,0.000963291,0.00041760187,0.002610081,0.9918002,7.764868e-7,0.000042575455,0.0025973795],"study_design_scores_gemma":[0.00047708265,0.0004282034,0.00066874677,0.0008835431,0.00026595307,0.000101458696,0.000551997,0.00026381126,0.99588346,3.1577977e-7,0.00016804534,0.0003073629],"about_ca_topic_score_codex":0.00010703992,"about_ca_topic_score_gemma":0.0001346861,"teacher_disagreement_score":0.0040832944,"about_ca_system_score_codex":0.00004248143,"about_ca_system_score_gemma":0.00018458632,"threshold_uncertainty_score":0.80772805},"labels":[],"label_agreement":null},{"id":"W2093916465","doi":"10.1074/jbc.m114.627356","title":"Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; PROTEO; Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Arrestin; Gq alpha subunit; Identification (biology); G protein-coupled receptor; Receptor; Chemistry; Cell biology; Signal transduction; Angiotensin II; G protein; Biology; Biochemistry","score_opus":0.019729777762191675,"score_gpt":0.23222144254352323,"score_spread":0.21249166478133155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093916465","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996517,0.00022505809,0.0026645197,0.00031216492,0.0000471501,0.00015869671,0.00004454798,0.0000019471038,0.000028904613],"genre_scores_gemma":[0.99962145,0.0000046466394,0.00021083801,0.000023992412,0.00005111663,0.0000016179399,0.000032472875,0.000006093549,0.00004776994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990943,0.0001290098,0.00041209042,0.00008983779,0.00017932012,0.00009541866],"domain_scores_gemma":[0.99828273,0.000055400847,0.0008451895,0.00017873455,0.00059512065,0.00004282127],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068905635,0.00009926147,0.00017659031,0.000008713451,0.00012274497,0.000016798094,0.00021352475,0.00013687456,0.00000778224],"category_scores_gemma":[0.00095108344,0.000042521075,0.000096026444,0.00013236591,0.00030617585,0.0000061234527,0.00008645978,0.00013759131,6.0642556e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000113512746,0.000036096408,0.0004683276,0.000006318143,0.000051676954,3.533074e-7,0.00008959315,0.0013331859,0.9976966,0.00011634629,0.000014735697,0.000073283365],"study_design_scores_gemma":[0.00062424666,0.00014536668,0.0003135108,0.000056206478,0.00003884915,0.000018538418,0.0003491598,0.0039424105,0.99402106,0.00024753239,0.00016850699,0.00007461962],"about_ca_topic_score_codex":0.0000053531817,"about_ca_topic_score_gemma":0.000003883702,"teacher_disagreement_score":0.0036755176,"about_ca_system_score_codex":0.000027133516,"about_ca_system_score_gemma":0.0001759968,"threshold_uncertainty_score":0.17339592},"labels":[],"label_agreement":null},{"id":"W2094064816","doi":"10.1002/jcp.22321","title":"Gender differences in β‐adrenoceptor system in cardiac hypertrophy due to arteriovenous fistula","year":2010,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Internal medicine; Endocrinology; Shunt (medical); Epinephrine; Muscle hypertrophy; Biology; Cardiac output; Medicine; Hemodynamics","score_opus":0.008303782176627257,"score_gpt":0.20439117167553794,"score_spread":0.1960873894989107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094064816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970398,0.00041107833,0.0010604414,0.000026460906,0.0012317318,0.00011024276,0.000005089194,0.0000026041353,0.00011255621],"genre_scores_gemma":[0.9982604,0.00002908776,0.00083170657,0.00007236755,0.00074649986,0.0000066263424,0.000008120794,0.000018018649,0.000027190623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877733,0.00015199462,0.0004440202,0.00022662425,0.00012722364,0.00027280915],"domain_scores_gemma":[0.99940956,0.000018549856,0.00018006876,0.00020086455,0.00008347769,0.000107472195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033907648,0.00015847335,0.0004970835,0.00014379185,0.000029412502,0.0000151427275,0.00025350964,0.000206291,0.00007262285],"category_scores_gemma":[0.000037698268,0.00013031175,0.00016796625,0.00009849928,0.000032780943,0.000005322211,0.000062956075,0.00029489264,0.000008452663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011617301,0.000071143244,0.0008414579,0.000024365374,0.000033244138,0.000050814117,0.00014368695,0.0000625663,0.99803454,0.00010320456,0.000059584672,0.0004592154],"study_design_scores_gemma":[0.0007162186,0.00084201194,0.023514915,0.000042958465,0.00001707871,0.00010569667,0.0004373588,0.000076812816,0.9710846,0.00020627219,0.002683213,0.0002728532],"about_ca_topic_score_codex":0.000023046177,"about_ca_topic_score_gemma":0.000016697433,"teacher_disagreement_score":0.026949935,"about_ca_system_score_codex":0.000022043308,"about_ca_system_score_gemma":0.00008156829,"threshold_uncertainty_score":0.5313959},"labels":[],"label_agreement":null},{"id":"W2094145743","doi":"10.1016/j.cellsig.2009.09.020","title":"Role of the extracellular amino terminus and first membrane-spanning helix of dopamine D1 and D5 receptors in shaping ligand selectivity and efficacy","year":2009,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Partial agonist; Functional selectivity; Receptor; Agonist; Chemistry; Intrinsic activity; Allosteric regulation; Transmembrane domain; Ligand (biochemistry); Inverse agonist; Cell biology; Biochemistry; Biology","score_opus":0.009467689215610997,"score_gpt":0.20839258066063102,"score_spread":0.19892489144502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094145743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9821092,0.015522745,0.0020315768,0.00003153299,0.00004068275,0.00022230504,0.0000020591701,0.0000058775636,0.000034046978],"genre_scores_gemma":[0.9986723,0.00055956066,0.0005931241,0.000015220459,0.00006585495,0.0000029551575,0.0000069086873,0.00001914364,0.00006493035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988174,0.0000721357,0.00034651143,0.0003898314,0.00013860699,0.00023551297],"domain_scores_gemma":[0.9994755,0.000053435797,0.0001790644,0.00017387114,0.000047986305,0.00007017995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045490323,0.00019954261,0.0003027185,0.00007224813,0.00013607892,0.000033881497,0.00012464038,0.00016551316,0.0000063570506],"category_scores_gemma":[0.000073018564,0.00017228701,0.00006177642,0.00013361742,0.00012047896,0.000011717754,0.000092073176,0.00015053472,9.7666224e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049245653,0.000047593036,0.0024134002,0.000071934875,0.000020146785,0.0000026472153,0.0005163388,0.0005140321,0.9891091,0.000034193567,9.621724e-7,0.0072204308],"study_design_scores_gemma":[0.00061255647,0.00025361258,0.0009551762,0.00022696417,0.00002915422,0.0000147332075,0.0001902646,0.0031343237,0.9939664,0.00008926106,0.00034120434,0.00018634467],"about_ca_topic_score_codex":0.000035481484,"about_ca_topic_score_gemma":0.000016802409,"teacher_disagreement_score":0.016563129,"about_ca_system_score_codex":0.000008074132,"about_ca_system_score_gemma":0.000028368575,"threshold_uncertainty_score":0.702566},"labels":[],"label_agreement":null},{"id":"W2094255469","doi":"10.1523/jneurosci.1226-13.2013","title":"Opiate Exposure and Withdrawal Induces a Molecular Memory Switch in the Basolateral Amygdala between ERK1/2 and CaMKIIα-Dependent Signaling Substrates","year":2013,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Opiate; Basolateral amygdala; Dopamine; Neuroscience; Psychology; Conditioned place preference; Amygdala; Ventral tegmental area; Chemistry; Receptor; Dopaminergic","score_opus":0.011633763377932696,"score_gpt":0.23403821396294602,"score_spread":0.22240445058501332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094255469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985677,0.0005119677,0.0004084873,0.0002712745,0.0001042776,0.00011360844,0.0000013282012,0.0000015285275,0.000019831563],"genre_scores_gemma":[0.99918365,0.000106395986,0.00024735826,0.00033500444,0.00009757667,0.0000032236512,5.0682786e-7,0.000008190831,0.000018100196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892765,0.0001162792,0.00028664607,0.000215538,0.0002515606,0.0002023387],"domain_scores_gemma":[0.99952596,0.000026644593,0.00017960677,0.00010742628,0.000069898895,0.0000904686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005433417,0.00012390551,0.00015426769,0.00006220261,0.000090763824,0.00019160642,0.00026603637,0.00006897635,0.000004976072],"category_scores_gemma":[0.00006305131,0.00008135702,0.000038621478,0.00009636621,0.00008576435,0.000036799625,0.000066672765,0.00021183715,3.0023804e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000089247715,0.000013417022,0.007625587,0.000006261076,0.000003820614,0.000028840494,0.00021743582,0.0001071794,0.9913282,0.000008054191,0.0000056009026,0.0006467134],"study_design_scores_gemma":[0.0004830681,0.0008080209,0.058686078,0.000041158717,0.000015989599,0.00034781406,0.0005335994,0.00012214144,0.93841845,0.00033894563,0.000045541008,0.00015919433],"about_ca_topic_score_codex":0.00002972231,"about_ca_topic_score_gemma":0.000003758208,"teacher_disagreement_score":0.052909713,"about_ca_system_score_codex":0.000004662976,"about_ca_system_score_gemma":0.000047459966,"threshold_uncertainty_score":0.3317643},"labels":[],"label_agreement":null},{"id":"W2094428711","doi":"10.1038/sj.npp.1300640","title":"Alterations in Behavioral Responses to a Cholinergic Agonist in Post-Pubertal Rats with Neonatal Ventral Hippocampal Lesions: Relationship to Changes in Muscarinic Receptor Levels","year":2004,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research","keywords":"Oxotremorine; Endocrinology; Internal medicine; Muscarinic acetylcholine receptor; Cholinergic; Muscarinic acetylcholine receptor M1; Nucleus accumbens; Chemistry; Neuroscience; Medicine; Psychology; Receptor","score_opus":0.030286399583663515,"score_gpt":0.3272751649049634,"score_spread":0.29698876532129986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094428711","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956357,0.000088086876,0.00011411069,0.0027303873,0.0005777215,0.00074974453,0.000059952374,0.0000151756485,0.000029109291],"genre_scores_gemma":[0.9953216,0.000021632659,0.0015030159,0.0023391605,0.00018424926,0.00031743094,0.00010409013,0.000042178424,0.0001666428],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9980653,0.00028288388,0.00037299498,0.0006369943,0.0001390392,0.0005028245],"domain_scores_gemma":[0.999398,0.000047177487,0.000063444306,0.00022411406,0.0000678484,0.00019944407],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023732784,0.00024436277,0.00023506767,0.0004440308,0.00008126709,0.000033693,0.00023746336,0.00017645398,0.00012480067],"category_scores_gemma":[0.00010150231,0.0002501897,0.000049231116,0.0005685292,0.000044576063,0.000015139685,0.00008253884,0.000352069,0.000031091233],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025838213,0.00028980826,0.009381718,0.0000050498847,0.0000063745388,0.00014698549,0.0007833546,0.0055014924,0.9799963,0.000055539032,0.00006658225,0.0011829671],"study_design_scores_gemma":[0.012067618,0.00740483,0.5057168,0.00015915447,0.000037309826,0.00019234062,0.000757489,0.000047124435,0.4683363,0.00010599066,0.0040106247,0.0011644303],"about_ca_topic_score_codex":0.00014912519,"about_ca_topic_score_gemma":0.009645104,"teacher_disagreement_score":0.51166,"about_ca_system_score_codex":0.00009367548,"about_ca_system_score_gemma":0.00021953405,"threshold_uncertainty_score":0.99999505},"labels":[],"label_agreement":null},{"id":"W2094619489","doi":"10.1038/sj.mp.4001268","title":"Evidence that a single nucleotide polymorphism in the promoter of the G protein receptor kinase 3 gene is associated with bipolar disorder","year":2003,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia; University of Toronto","funders":"National Center for Research Resources; National Institute of Mental Health","keywords":"Genetics; Biology; Single-nucleotide polymorphism; Locus (genetics); Transmission disequilibrium test; Gene; Linkage disequilibrium; Exon; Allele; Untranslated region; Genotype; Messenger RNA","score_opus":0.012890241049589347,"score_gpt":0.2128033178582902,"score_spread":0.19991307680870085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094619489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9880173,0.008121399,0.0017666818,0.0010540697,0.00020889846,0.00071611826,0.000012881088,0.0000068115296,0.00009580452],"genre_scores_gemma":[0.9968059,0.000033601787,0.0018291147,0.0010327871,0.000038766713,0.000062654886,0.000011362258,0.000042643187,0.00014318807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982801,0.0004372513,0.00024098324,0.0003887421,0.000346559,0.0003063277],"domain_scores_gemma":[0.9989974,0.000010294405,0.00023987678,0.00064828154,0.00006075064,0.00004342594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046805615,0.0002242911,0.00017453062,0.000039852057,0.00010514048,0.000034636167,0.00042629632,0.0001412028,0.000078517245],"category_scores_gemma":[0.00013064532,0.00013524585,0.00016030563,0.00031225334,0.00009200993,0.000008045436,0.00005392311,0.00018660778,0.000002696221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041654414,0.00026917717,0.008156561,0.00001795756,0.000057165813,0.0000042520096,0.00015663284,0.000015569096,0.9906768,0.00018084604,0.00017890356,0.00024448716],"study_design_scores_gemma":[0.00056761486,0.00040687638,0.00068440737,0.00029706335,0.0000333805,0.000015829895,0.00016273557,0.000010983876,0.9934958,0.00033257363,0.0037555315,0.00023719705],"about_ca_topic_score_codex":0.000041880656,"about_ca_topic_score_gemma":0.00007790409,"teacher_disagreement_score":0.008788546,"about_ca_system_score_codex":0.000017519093,"about_ca_system_score_gemma":0.0001365024,"threshold_uncertainty_score":0.5515166},"labels":[],"label_agreement":null},{"id":"W2094714066","doi":"10.1177/1087057105275344","title":"High-Throughput Screening of G Protein-Coupled Receptor Antagonists Using a Bioluminescence Resonance Energy Transfer 1-Based β-Arrestin2 Recruitment Assay","year":2005,"lang":"en","type":"article","venue":"SLAS DISCOVERY","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":178,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal","funders":"","keywords":"G protein-coupled receptor; Agonist; Receptor; Bioluminescence; HEK 293 cells; Chemokine receptor; Cell biology; High-throughput screening; Biology; Chemistry; Biochemistry; Chemokine","score_opus":0.028383811510955623,"score_gpt":0.2617637164937525,"score_spread":0.2333799049827969,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094714066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.64526206,0.0013676496,0.3526509,0.00008989188,0.00018017105,0.00033850598,0.000067292225,0.000016806685,0.000026696704],"genre_scores_gemma":[0.9627502,0.000108470456,0.035790823,0.00016892457,0.00046124167,0.00008499891,0.00017724193,0.00005177231,0.00040635612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99810225,0.00012366293,0.0004672357,0.00059696054,0.00029614003,0.00041377492],"domain_scores_gemma":[0.9992237,0.0000212398,0.00013841505,0.00042380244,0.00010435516,0.000088501874],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000335511,0.00029935178,0.00031764322,0.0000615643,0.00012923527,0.000056447676,0.0002559859,0.00020249811,0.00008797837],"category_scores_gemma":[0.000056146884,0.000282027,0.00019438527,0.00017023529,0.00011790618,0.00003108762,0.00006351646,0.000101723694,0.0000023760747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032313485,0.00012352459,0.00020690507,0.0000339179,0.000040471576,0.000002613577,0.00002133914,0.002165128,0.9913417,0.0007701445,0.000078485034,0.0048926263],"study_design_scores_gemma":[0.00091975776,0.00029422587,0.00004509585,0.00023662327,0.000023604694,0.0000033096926,0.00003021426,0.005194065,0.9797235,0.000028681976,0.013151267,0.00034966893],"about_ca_topic_score_codex":0.00032532992,"about_ca_topic_score_gemma":0.00007954185,"teacher_disagreement_score":0.3174881,"about_ca_system_score_codex":0.000047370173,"about_ca_system_score_gemma":0.00020683522,"threshold_uncertainty_score":0.99996316},"labels":[],"label_agreement":null},{"id":"W2094733929","doi":"10.1002/ar.22550","title":"Distribution of Adenylyl Cyclases in the Rat Ovary by Immunofluorescence Microscopy","year":2012,"lang":"en","type":"article","venue":"The Anatomical Record","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Dalhousie University","keywords":"Immunofluorescence; Ovary; Cell biology; Indirect immunofluorescence; Chemistry; Distribution (mathematics); Chinese hamster ovary cell; Biology; Biochemistry; Endocrinology; Receptor; Immunology; Antibody","score_opus":0.008516316727893956,"score_gpt":0.2575790411011762,"score_spread":0.24906272437328222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094733929","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953673,0.0026724518,0.00140175,0.00018176934,0.00018231908,0.000113692455,0.00002497589,0.0000024952883,0.000053232307],"genre_scores_gemma":[0.9989089,0.0005035164,0.000108641056,0.00018604854,0.00010607677,0.000011758414,0.00012199437,0.0000071507393,0.000045957288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999287,0.00012011861,0.0001754711,0.00011297306,0.000092924834,0.00021151466],"domain_scores_gemma":[0.9996045,0.00004164225,0.000060747654,0.00024266551,0.000020618929,0.00002979954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003832109,0.000087287764,0.000098287186,0.000008284582,0.000053598378,0.000012059683,0.0002919122,0.000083462655,0.000039770945],"category_scores_gemma":[0.00007177564,0.000050423925,0.00006794915,0.00007996325,0.00007768743,0.0000050173503,0.00006015137,0.00011238271,0.0000065959307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008280943,0.00005712239,0.0020440137,0.00000363479,0.00000812027,1.7446577e-7,0.000042347183,6.8336914e-7,0.987557,0.0002404185,0.007584528,0.0023791501],"study_design_scores_gemma":[0.00015176731,0.00007056341,0.0012002701,0.000011839933,0.0000084797975,0.000004228428,0.00012404051,0.000026726198,0.96650445,0.00016527809,0.031657152,0.00007517225],"about_ca_topic_score_codex":0.00008755571,"about_ca_topic_score_gemma":0.0000050783906,"teacher_disagreement_score":0.024072625,"about_ca_system_score_codex":0.000011671942,"about_ca_system_score_gemma":0.000017573691,"threshold_uncertainty_score":0.2056228},"labels":[],"label_agreement":null},{"id":"W2094743955","doi":"10.1074/jbc.m110.142257","title":"ANKRD13C Acts as a Molecular Chaperone for G Protein-coupled Receptors","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Cell biology; G protein-coupled receptor; Receptor; Biology; Endoplasmic reticulum; Chaperone (clinical); Endoplasmic-reticulum-associated protein degradation; ER retention; Signal transduction; Biochemistry; Unfolded protein response","score_opus":0.01187077850906636,"score_gpt":0.25113969635816885,"score_spread":0.23926891784910248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094743955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957695,0.00030454228,0.0028179304,0.00019699469,0.00027385147,0.00019194426,0.0000058276355,0.00000844132,0.00043098448],"genre_scores_gemma":[0.9913123,0.00005653333,0.0071865986,0.00017082748,0.0008489505,0.000021781561,0.000032556636,0.000020743366,0.0003496716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998836,0.000022387067,0.0004135359,0.00026968046,0.00016338384,0.00029505783],"domain_scores_gemma":[0.9989496,0.000018438997,0.00034809715,0.00020576325,0.00026512085,0.0002129986],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047579868,0.00020125524,0.00028332518,0.000019319617,0.00006940282,0.000031395168,0.00034881677,0.00048765796,0.0005358987],"category_scores_gemma":[0.0007592732,0.00014536617,0.00031037306,0.00005902174,0.000087312466,0.0000053211324,0.00007069565,0.00034356565,0.0000039226315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029313628,0.00009020238,0.00004302644,0.000021093936,0.000056419118,0.000010796438,0.00000799302,0.0000059234794,0.9984407,0.000092086244,0.00013752622,0.0008011406],"study_design_scores_gemma":[0.0007064172,0.0007471315,0.000014336859,0.00001987216,0.000014801626,0.00014382244,0.00004650793,0.000020882931,0.9684779,0.00070282345,0.028909082,0.00019641574],"about_ca_topic_score_codex":9.455984e-7,"about_ca_topic_score_gemma":2.9221258e-7,"teacher_disagreement_score":0.02996275,"about_ca_system_score_codex":0.000011335163,"about_ca_system_score_gemma":0.00010711952,"threshold_uncertainty_score":0.592786},"labels":[],"label_agreement":null},{"id":"W2094993972","doi":"10.1016/j.pbiomolbio.2003.11.007","title":"Functional genomics as an emerging strategy for the investigation of central mechanisms in experimental hypertension","year":2003,"lang":"en","type":"review","venue":"Progress in Biophysics and Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Functional genomics; Pathogenesis; Biology; Gene expression profiling; Phenotype; Bioinformatics; Candidate gene; Genomics; Gene; Gene expression; Computational biology; Neuroscience; Medicine; Genetics; Genome; Immunology","score_opus":0.04481593392587529,"score_gpt":0.324937753569898,"score_spread":0.2801218196440227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094993972","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.047479212,0.9455202,0.0058203414,0.000010276775,0.00026037847,0.0008735699,0.000027187029,0.000003520373,0.000005311788],"genre_scores_gemma":[0.116755545,0.8786084,0.0028404894,0.00009865112,0.00013054485,0.0004199957,0.0010716215,0.000068502115,0.0000062256995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998527,0.00016969218,0.00041957747,0.00051494833,0.00006920752,0.00029955618],"domain_scores_gemma":[0.9994143,0.00002007707,0.00023118152,0.00022890762,0.000048121485,0.000057367946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023715945,0.00029355387,0.0005337798,0.00008514932,0.000056778106,0.000019553443,0.00016440488,0.00038357798,0.0000044298713],"category_scores_gemma":[0.000009260391,0.00022387916,0.00016914986,0.00011381892,0.00014688505,0.0000048394572,0.000081755396,0.00013504192,2.5936274e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079531135,0.00015795216,0.000032975207,0.0007272946,0.00015339715,0.000005974372,0.00005919827,0.00005035464,0.5525261,0.03868469,0.0000051980846,0.40751734],"study_design_scores_gemma":[0.0027826112,0.0039338614,0.000034557095,0.0014657709,0.0004684415,0.000117130054,0.0006127217,0.0010665981,0.8733918,0.031279076,0.08302723,0.0018201882],"about_ca_topic_score_codex":0.000014655748,"about_ca_topic_score_gemma":0.0000039528754,"teacher_disagreement_score":0.40569717,"about_ca_system_score_codex":0.00002581739,"about_ca_system_score_gemma":0.00016458178,"threshold_uncertainty_score":0.9129527},"labels":[],"label_agreement":null},{"id":"W2095194339","doi":"10.1073/pnas.1117268109","title":"Effect of channel mutations on the uptake and release of the retinal ligand in opsin","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canada Excellence Research Chairs, Government of Canada; Deutsche Forschungsgemeinschaft","keywords":"Rhodopsin; Retinaldehyde; Retinal; Opsin; Ligand (biochemistry); Biophysics; Transmembrane domain; Chemistry; Photoswitch; Biology; Stereochemistry; Receptor; Biochemistry; Photochemistry","score_opus":0.020832651948214046,"score_gpt":0.28448894359275995,"score_spread":0.2636562916445459,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095194339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982778,0.00020031988,6.838999e-7,0.00079773844,0.000015399299,0.00012821247,0.000006258279,4.9119e-7,0.00057312095],"genre_scores_gemma":[0.99976325,0.000028340055,0.00007505395,0.000059775924,0.000037096095,0.000005490337,1.076066e-7,0.0000018360134,0.000029078139],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932384,0.000014494119,0.00017317027,0.000087863395,0.00032387392,0.00007677284],"domain_scores_gemma":[0.99959815,0.00006974035,0.00023622978,0.0000090980975,0.00007324251,0.000013548756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016609574,0.00004954442,0.00007642332,0.000034608616,0.00007723358,0.0000042598417,0.00027376672,0.00005068247,0.0000027583906],"category_scores_gemma":[0.00061965507,0.00002312203,0.00004389928,0.00020503733,0.00036728458,0.000011019018,0.00007208759,0.00006848606,5.804574e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026012402,0.000017166525,0.0023921228,0.00002914169,0.0000049354394,3.7290607e-10,0.00015202389,0.00004574419,0.9905754,0.0065289354,0.00004186753,0.00018666044],"study_design_scores_gemma":[0.00010066539,0.00011963343,0.015464376,0.000070433045,0.0000065085947,0.0000016516225,0.00013985731,0.00015305016,0.9813125,0.0025757013,0.000030770767,0.000024822642],"about_ca_topic_score_codex":0.0000033701567,"about_ca_topic_score_gemma":5.728504e-8,"teacher_disagreement_score":0.013072253,"about_ca_system_score_codex":0.0000035439375,"about_ca_system_score_gemma":0.000013342558,"threshold_uncertainty_score":0.13532753},"labels":[],"label_agreement":null},{"id":"W2095318905","doi":"10.1111/j.1460-9568.2006.04875.x","title":"Disparate cholinergic currents in rat principal trigeminal sensory nucleus neurons mediated by M1 and M2 receptors: a possible mechanism for selective gating of afferent sensory neurotransmission","year":2006,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; National Sleep Foundation","keywords":"Neuroscience; Sensory gating; Sensory system; Gating; Afferent; Mechanism (biology); Cholinergic; Nucleus; Chemistry; Psychology; Physics","score_opus":0.01967342052915802,"score_gpt":0.259958904412636,"score_spread":0.240285483883478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095318905","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940547,0.0001801388,0.00486177,0.000058080073,0.0005169587,0.0002021185,0.000029779954,0.000005878589,0.000090587106],"genre_scores_gemma":[0.99849737,0.00028606705,0.0007310092,0.00009793437,0.00013684141,0.0000019168142,0.0000075986704,0.000034839348,0.00020645602],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979478,0.00044174131,0.0006254836,0.00038903183,0.00027507407,0.00032085428],"domain_scores_gemma":[0.9989922,0.00004768708,0.00050904305,0.00012698944,0.00017618113,0.00014790449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006320618,0.00021085955,0.00025959164,0.00012794248,0.000116442105,0.000046295714,0.00026415286,0.000043000542,0.0000029005691],"category_scores_gemma":[0.00028638254,0.00018009079,0.0001038266,0.00019374328,0.00009808751,0.000025661993,0.00006854946,0.0002414442,4.0538265e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020035442,0.00011775183,0.00031165016,0.000023091268,0.0000026631872,0.000026625758,0.0000627773,0.00054735236,0.9977018,0.00002908364,0.00013712584,0.00083970453],"study_design_scores_gemma":[0.0016060797,0.0018141079,0.0018607406,0.00010833087,0.000019342684,0.00013406675,0.000045343793,0.0056389757,0.98703456,0.000050891504,0.0014677148,0.00021985114],"about_ca_topic_score_codex":0.0000038974613,"about_ca_topic_score_gemma":0.0000014828128,"teacher_disagreement_score":0.010667265,"about_ca_system_score_codex":0.000013375955,"about_ca_system_score_gemma":0.00006280461,"threshold_uncertainty_score":0.73438895},"labels":[],"label_agreement":null},{"id":"W2095664544","doi":"10.1074/jbc.m809150200","title":"Bioluminescence Resonance Energy Transfer Studies Reveal Constitutive Dimerization of the Human Lutropin Receptor and a Lack of Correlation between Receptor Activation and the Propensity for Dimerization","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"HEK 293 cells; Mutant; Receptor; Cell membrane; Dimer; Endoplasmic reticulum; Chemistry; Membrane; Biophysics; Cell biology; Biochemistry; Biology; Gene","score_opus":0.04592384333913631,"score_gpt":0.28123863581574804,"score_spread":0.23531479247661174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2095664544","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857573,0.0009784745,0.012819659,0.00022552749,0.000038315076,0.00015177834,0.0000145583745,0.0000014248219,0.000012957481],"genre_scores_gemma":[0.9988234,0.00054671784,0.00039440073,0.000040203842,0.00013824049,0.0000032838384,0.00002449361,0.0000030834647,0.00002616028],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992657,0.00008482274,0.00036229807,0.00012950525,0.00008637893,0.00007130453],"domain_scores_gemma":[0.9992142,0.00006320052,0.00035569735,0.000074398566,0.00026967592,0.000022839557],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029539195,0.000093182345,0.00025087383,0.000009010567,0.00009823686,0.0000061185615,0.00007781393,0.00013778995,0.00000281283],"category_scores_gemma":[0.00035869467,0.000049507544,0.000072360475,0.00006762943,0.00036371572,0.000007729764,0.00002433397,0.000074718846,9.696455e-9],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034405646,0.000020995865,0.002107004,0.00002386709,0.00003400011,2.255905e-8,0.000066998655,0.000022709506,0.99601036,0.00040685054,0.000025452819,0.0009376727],"study_design_scores_gemma":[0.0007703425,0.00030197416,0.0037778702,0.00011580324,0.000026567735,0.0000024735339,0.00009381051,0.000028668197,0.994349,0.00026680087,0.00020365759,0.00006305524],"about_ca_topic_score_codex":0.000002172541,"about_ca_topic_score_gemma":1.384608e-7,"teacher_disagreement_score":0.01306611,"about_ca_system_score_codex":0.000011526614,"about_ca_system_score_gemma":0.00003160041,"threshold_uncertainty_score":0.2018859},"labels":[],"label_agreement":null},{"id":"W2096089717","doi":"10.1002/anie.201302374","title":"Opsin, a Structural Model for Olfactory Receptors?","year":2013,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"G protein-coupled receptor; Opsin; Receptor; Computational biology; Computer science; Olfactory receptor; Rhodopsin; Olfactory system; Neuroscience; World Wide Web; Cognitive science; Information retrieval; Biology; Psychology; Genetics; Biochemistry","score_opus":0.021213504264174794,"score_gpt":0.2582315899245779,"score_spread":0.2370180856604031,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096089717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6391715,0.00017629057,0.35241076,0.0009014685,0.0038332567,0.00056200963,0.00019629992,0.000050061433,0.0026983651],"genre_scores_gemma":[0.988117,0.000038788046,0.0046653682,0.00043674713,0.0020015314,0.00016181018,0.0018464387,0.000022055472,0.0027102712],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929327,0.0000061432506,0.00015928385,0.00024312353,0.00014764504,0.00015051849],"domain_scores_gemma":[0.999474,0.000010209694,0.00007732974,0.00010996068,0.00026946721,0.00005905747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006542907,0.000118423326,0.00007905522,0.000032650732,0.00006521565,0.000051896248,0.00015537717,0.00012315378,0.0008142166],"category_scores_gemma":[0.000068835834,0.000112510344,0.00010323944,0.000021536558,0.000025303048,0.000023587836,0.000038842794,0.00005514358,0.000016045791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028133663,0.000012253257,0.000045306748,0.000006418374,0.00003803795,9.5698375e-8,0.00004230558,0.00022103866,0.9503748,0.00021025685,0.04804678,0.0009745931],"study_design_scores_gemma":[0.00037938252,0.000049539845,0.0000520879,0.000010447712,0.0000069516996,0.000003767877,0.000041477462,0.010144266,0.974063,0.0031380183,0.011964097,0.00014700925],"about_ca_topic_score_codex":0.000014793321,"about_ca_topic_score_gemma":0.000003982893,"teacher_disagreement_score":0.3489455,"about_ca_system_score_codex":0.000034348486,"about_ca_system_score_gemma":0.000030875755,"threshold_uncertainty_score":0.8915101},"labels":[],"label_agreement":null},{"id":"W2097114625","doi":"10.1002/jemt.20376","title":"FRET and colocalization analyzer—A method to validate measurements of sensitized emission FRET acquired by confocal microscopy and available as an ImageJ Plug‐in","year":2006,"lang":"en","type":"article","venue":"Microscopy Research and Technique","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Förster resonance energy transfer; Colocalization; Fluorophore; Confocal; Confocal microscopy; Fluorescence-lifetime imaging microscopy; Fluorescence; Chemistry; Physics; Optics; Biology; Molecular biology","score_opus":0.026861807312039618,"score_gpt":0.3715885479676801,"score_spread":0.34472674065564046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097114625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9388273,0.0008752394,0.05922279,0.00006004117,0.000013280268,0.00074308313,0.000065921435,0.000014182648,0.00017818378],"genre_scores_gemma":[0.91326016,0.00035595955,0.084893875,0.00010529669,0.000038613856,0.00008828949,0.0003402556,0.00004341938,0.00087410246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811727,0.00038316348,0.00030737184,0.0005682862,0.0002365652,0.00038736933],"domain_scores_gemma":[0.99924445,0.000028522256,0.000063529566,0.00023338517,0.00024248514,0.00018760712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020354944,0.00018040929,0.00027810477,0.00017229152,0.00014838719,0.00010301917,0.000116273106,0.00025877747,0.00004874743],"category_scores_gemma":[0.00005406812,0.00017400419,0.000023019384,0.00021682317,0.00017258001,0.000016197824,0.0001719215,0.00011870116,0.0000010721486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041119807,0.000074281015,0.0031018124,0.000054654494,0.00001207994,0.0000037022635,0.000029648767,0.0000012189456,0.9919412,0.000023791301,0.003998629,0.00034777494],"study_design_scores_gemma":[0.000742433,0.0009155577,0.00007567379,0.00008363799,0.0000068701356,0.000013995054,0.00004531257,0.00012495858,0.99473274,0.00069018576,0.0023947833,0.00017385972],"about_ca_topic_score_codex":0.0012607342,"about_ca_topic_score_gemma":0.00006733933,"teacher_disagreement_score":0.025671085,"about_ca_system_score_codex":0.00002511068,"about_ca_system_score_gemma":0.00008422343,"threshold_uncertainty_score":0.7095685},"labels":[],"label_agreement":null},{"id":"W2097744565","doi":"10.1124/pr.110.002642","title":"The Physiology, Signaling, and Pharmacology of Dopamine Receptors","year":2011,"lang":"en","type":"review","venue":"Pharmacological Reviews","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2721,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Dopamine; Dopamine receptor; D2-like receptor; Neuroscience; Dopamine receptor D3; Dopaminergic; D1-like receptor; Dopamine receptor D2; Signal transduction; Receptor; Biology; G protein-coupled receptor; Neurotransmitter receptor; Pharmacology; Cell biology","score_opus":0.08059251498401646,"score_gpt":0.3710735333519555,"score_spread":0.29048101836793905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097744565","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015705211,0.99686384,0.000084845626,0.000010925146,0.0011986167,0.0014439418,0.00001434908,0.000013360915,0.00021304307],"genre_scores_gemma":[0.000041341893,0.99729913,0.00034238904,0.0001642769,0.00080376846,0.00048687393,0.00008028524,0.000046610283,0.00073531613],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963849,0.0012085558,0.0011606064,0.0006901225,0.000097169584,0.00045863132],"domain_scores_gemma":[0.9982649,0.00021907025,0.00097363617,0.00029131948,0.00007839475,0.00017269824],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013696108,0.0005634901,0.0018500674,0.000049326274,0.00018481213,0.000015413974,0.0006861815,0.00048372895,0.0011855075],"category_scores_gemma":[0.00018367547,0.0002988977,0.0007240326,0.00016367056,0.0004049306,0.0000035061303,0.00043497348,0.00046222514,0.0000451688],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003510125,0.000065348104,3.1622278e-7,0.0021905801,0.00027233062,9.2740777e-7,0.0000056632007,2.0086462e-7,0.09669232,0.000070673836,0.00913699,0.89152956],"study_design_scores_gemma":[0.0002019519,0.0003576299,1.3648324e-7,0.000541155,0.00094342086,0.000016788632,0.0000037784746,0.0000013373066,0.016369741,0.000032909462,0.9812115,0.0003196423],"about_ca_topic_score_codex":0.0000033014867,"about_ca_topic_score_gemma":6.663886e-7,"teacher_disagreement_score":0.9720745,"about_ca_system_score_codex":0.000017458517,"about_ca_system_score_gemma":0.00009015067,"threshold_uncertainty_score":0.9999463},"labels":[],"label_agreement":null},{"id":"W2097986303","doi":"10.1042/bst0321040","title":"Small GTP-binding protein-coupled receptors","year":2004,"lang":"en","type":"review","venue":"Biochemical Society Transactions","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"Heterotrimeric G protein; G protein-coupled receptor; Rhodopsin-like receptors; G protein; GTPase; Rab; Cell biology; GTPase-activating protein; Biology; Ras superfamily; CDC42; Guanine nucleotide exchange factor; GTP-binding protein regulators; Signal transduction; Receptor; Biochemistry; GTP'","score_opus":0.03288815143079686,"score_gpt":0.27244315199052455,"score_spread":0.23955500055972767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2097986303","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00042763154,0.9511638,0.04658943,0.000025643049,0.0004904081,0.0010473297,0.00010686337,0.00008408421,0.00006479835],"genre_scores_gemma":[0.00009436993,0.985698,0.009698232,0.000027566915,0.00047285316,0.0004291606,0.0009581787,0.0001470455,0.002474599],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99760956,0.000059487676,0.00062077504,0.0009118445,0.0002266774,0.0005716726],"domain_scores_gemma":[0.99893296,0.000019922063,0.00023606139,0.00047986835,0.000076406664,0.00025477412],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00021118463,0.0006435158,0.0009081713,0.000041501862,0.00029775035,0.00006895334,0.00043656176,0.0015079918,0.00050634885],"category_scores_gemma":[0.000022183902,0.0005888986,0.0024178245,0.00031599047,0.0001257332,0.0000043727514,0.000035771693,0.00066378317,0.00006175543],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021198683,0.0004022603,1.0396892e-7,0.012695313,0.0016218416,0.0000031082075,0.000096165895,0.000016242613,0.76215595,0.0000541221,0.0013506445,0.22158304],"study_design_scores_gemma":[0.00033342125,0.00010449897,7.645624e-9,0.0033584281,0.0005404446,0.00002552842,0.00005428245,0.0000064051465,0.11076572,0.000020496693,0.8840014,0.0007894169],"about_ca_topic_score_codex":0.000019961879,"about_ca_topic_score_gemma":0.0000020809812,"teacher_disagreement_score":0.88265073,"about_ca_system_score_codex":0.00020735577,"about_ca_system_score_gemma":0.0004963073,"threshold_uncertainty_score":0.9997883},"labels":[],"label_agreement":null},{"id":"W2098505003","doi":"10.1016/j.neuropharm.2005.01.006","title":"M3-like muscarinic receptors mediate Ca2+ influx in rat mesencephalic GABAergic neurones through a protein kinase C-dependent mechanism","year":2005,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Muscarinic acetylcholine receptor; GABAergic; Chemistry; Mechanism (biology); Cell biology; Protein kinase C; Neuroscience; Protein kinase A; Receptor; Pharmacology; Biology; Signal transduction; Kinase; Biochemistry; Physics","score_opus":0.01286444889867267,"score_gpt":0.2651277624206837,"score_spread":0.25226331352201103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2098505003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99593353,0.00085186516,0.00014722435,0.0006132583,0.0015027515,0.0006831225,0.0000069175917,0.000047606845,0.00021370316],"genre_scores_gemma":[0.9943297,0.0010077668,0.00065234466,0.0023075321,0.00052314845,0.00021069935,0.00002220516,0.000071668794,0.0008749381],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99733764,0.00045917663,0.00048773133,0.00086257886,0.00022564034,0.00062722166],"domain_scores_gemma":[0.9992459,0.000040880914,0.0001608415,0.00030689102,0.000066399276,0.00017907743],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028938032,0.0003726746,0.0003489617,0.00012256934,0.00011674102,0.000032517215,0.00035085232,0.000275861,0.0005287389],"category_scores_gemma":[0.0000871498,0.0003693572,0.00010454566,0.00018596604,0.000107335116,0.000024576444,0.0003491718,0.00040125853,0.000061045204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019300813,0.00011456979,0.00006912088,0.000021515028,0.000023014338,0.00012336964,0.00018178548,0.00018035411,0.99635524,0.0003690902,0.00031574155,0.0020532142],"study_design_scores_gemma":[0.0018781698,0.0006147164,0.000076324985,0.000012320042,0.00003107107,0.00008262498,0.000073616844,0.0002856758,0.96815884,0.00028370752,0.028126322,0.00037662376],"about_ca_topic_score_codex":0.00005902541,"about_ca_topic_score_gemma":0.000078898156,"teacher_disagreement_score":0.028196389,"about_ca_system_score_codex":0.000035452715,"about_ca_system_score_gemma":0.00009516493,"threshold_uncertainty_score":0.99987584},"labels":[],"label_agreement":null},{"id":"W2099228763","doi":"10.1074/jbc.m110.166454","title":"Neurotensin Triggers Dopamine D2 Receptor Desensitization through a Protein Kinase C and β-Arrestin1-dependent Mechanism","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Ottawa Hospital; University of Ottawa; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Dopamine receptor D2; Autoreceptor; Internalization; Homologous desensitization; Protein kinase C; Cell biology; Receptor; Neurotensin; Agonist; Chemistry; Biology; Phosphorylation; Neuropeptide; Biochemistry","score_opus":0.031473803322184905,"score_gpt":0.23272477646085638,"score_spread":0.20125097313867146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099228763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99006695,0.0004840542,0.008782017,0.00006751218,0.00012041656,0.00013029866,0.0000072584567,0.000010199063,0.0003313103],"genre_scores_gemma":[0.9895238,0.000280648,0.009555803,0.00010373449,0.0003532429,0.0000046412147,0.000017940587,0.000016843273,0.00014330825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988369,0.00008013648,0.00041838965,0.00028004017,0.00016190678,0.0002226354],"domain_scores_gemma":[0.9991369,0.000014343038,0.00034748088,0.00015226753,0.00020382524,0.00014513166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034474966,0.00019730326,0.0002604135,0.000019390349,0.00007020574,0.000022945738,0.00016037941,0.00029372104,0.00021487259],"category_scores_gemma":[0.0003365972,0.00014408528,0.00012037831,0.00006910601,0.0000861791,0.000009826898,0.00008923995,0.00022124301,0.0000023880775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031964065,0.00008048718,0.00006419261,0.000019138814,0.00003361674,0.00006333331,0.000031236676,0.0000022764161,0.9984815,0.000055878005,0.000058846235,0.000789829],"study_design_scores_gemma":[0.0005985342,0.00063566683,0.00006253629,0.000043426946,0.00001819367,0.0003495419,0.00012647535,0.000013965601,0.9961086,0.0011184207,0.00074214005,0.00018247984],"about_ca_topic_score_codex":0.0000050691096,"about_ca_topic_score_gemma":2.5080868e-7,"teacher_disagreement_score":0.0023729058,"about_ca_system_score_codex":0.000015864436,"about_ca_system_score_gemma":0.000047398156,"threshold_uncertainty_score":0.58756274},"labels":[],"label_agreement":null},{"id":"W2099839597","doi":"10.1021/bi051292p","title":"Purification and Characterization of a Recombinant G-Protein-Coupled Receptor, <i>Saccharomyces cerevisiae</i> Ste2p, Transiently Expressed in HEK293 EBNA1 Cells","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Plant Biotechnology Institute; Biotechnology Research Institute; University of Saskatchewan","funders":"University of Saskatchewan","keywords":"Fusion protein; G protein-coupled receptor; Green fluorescent protein; Saccharomyces cerevisiae; Chemistry; Ligand (biochemistry); Biochemistry; Receptor; HEK 293 cells; Affinity chromatography; Heterologous expression; Ligand binding assay; Endosome; Recombinant DNA; Biophysics; Biology; Yeast","score_opus":0.005761556083602085,"score_gpt":0.20031503574928006,"score_spread":0.194553479665678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099839597","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980928,0.000568941,0.0006818292,0.00015613734,0.00008583606,0.00030021922,0.000032176693,0.000011522582,0.00007056908],"genre_scores_gemma":[0.99671644,0.000654769,0.0015388533,0.00004068973,0.00014260458,0.00005597537,0.00031607194,0.00002486402,0.0005097586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987834,0.000038180184,0.0003985101,0.00043582218,0.00013522322,0.00020885744],"domain_scores_gemma":[0.99935704,0.0000061197065,0.00019655262,0.0002927339,0.00007141521,0.00007615772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021482233,0.00018928718,0.00022120276,0.00003894946,0.00003999644,0.000025576326,0.00015901063,0.0002330868,0.00009395329],"category_scores_gemma":[0.000019231564,0.00019482015,0.00006647254,0.0001019866,0.000045195753,0.00001206727,0.000037059344,0.000085129155,0.0000032161797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000896406,0.000105452076,0.00007116471,0.00012633359,0.000012956095,3.7668246e-7,0.00007658439,0.0000046095547,0.99650204,0.0000121980875,0.0000521864,0.0029464539],"study_design_scores_gemma":[0.0006873751,0.00007889943,0.00010270897,0.00011042739,0.000007868173,0.0000022324189,0.000070563285,0.0002032091,0.99462664,0.000009669843,0.0038872976,0.0002131103],"about_ca_topic_score_codex":0.000010363897,"about_ca_topic_score_gemma":0.0000017277051,"teacher_disagreement_score":0.0038351112,"about_ca_system_score_codex":0.000019328827,"about_ca_system_score_gemma":0.000051464816,"threshold_uncertainty_score":0.7944535},"labels":[],"label_agreement":null},{"id":"W2099860892","doi":"10.1117/1.3484751","title":"Actin cytoskeleton-dependent Rab GTPase-regulated angiotensin type I receptor lysosomal degradation studied by fluorescence lifetime imaging microscopy","year":2010,"lang":"en","type":"article","venue":"Journal of Biomedical Optics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Institutes of Health; Université de Sherbrooke; Georgetown University; Lombardi Comprehensive Cancer Center, Georgetown University; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; W. M. Keck Foundation","keywords":"Förster resonance energy transfer; Angiotensin II; Alexa Fluor; Chemistry; Cell biology; Fluorophore; Biophysics; Green fluorescent protein; Endosome; Fluorescence microscope; LAMP1; Fluorescence; Receptor; Biology; Biochemistry","score_opus":0.005248665445193926,"score_gpt":0.24895838192616257,"score_spread":0.24370971648096865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099860892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905425,0.00049110496,0.0055471906,0.0013081786,0.0019534198,0.00010752914,0.000019727104,0.000010478695,0.000019883133],"genre_scores_gemma":[0.9426971,0.00042442634,0.054647613,0.0002603473,0.0013909276,0.0000012802686,0.00015235726,0.00004882219,0.00037713803],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982453,0.00007134653,0.00060550886,0.0002550138,0.0004945773,0.00032823737],"domain_scores_gemma":[0.9985494,0.000032311535,0.00043274974,0.00021904682,0.0004482825,0.00031820417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006177528,0.00020992367,0.0002933556,0.00009852158,0.00011210643,0.00006445354,0.00031293192,0.00027622175,0.0001559308],"category_scores_gemma":[0.00040403788,0.00017322977,0.00015006047,0.00018385377,0.00016140686,0.000015952899,0.00009583244,0.0004564688,0.0000136165045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020113892,0.00015978495,0.00016609955,0.000007339556,0.00009159501,0.000016738923,0.000027640604,0.0000030030594,0.9783138,0.000012484104,0.0158196,0.005180747],"study_design_scores_gemma":[0.0009778608,0.0005437414,0.0000751661,0.00004471032,0.00005582704,0.00011727546,0.00008304387,0.00047615176,0.97907895,0.000025038982,0.018307867,0.00021435162],"about_ca_topic_score_codex":0.000008224207,"about_ca_topic_score_gemma":0.0000014600262,"teacher_disagreement_score":0.049100425,"about_ca_system_score_codex":0.000029809928,"about_ca_system_score_gemma":0.0002022951,"threshold_uncertainty_score":0.7064105},"labels":[],"label_agreement":null},{"id":"W2099927887","doi":"10.1073/pnas.052713999","title":"Solution NMR spectroscopy of [α- <sup>15</sup> N]lysine-labeled rhodopsin: The single peak observed in both conventional and TROSY-type HSQC spectra is ascribed to Lys-339 in the carboxyl-terminal peptide sequence","year":2002,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Plant Biotechnology Institute","funders":"National Institute of General Medical Sciences","keywords":"Rhodopsin; Chemistry; Nuclear magnetic resonance spectroscopy; Micelle; Spectroscopy; Crystallography; Photoprotein; Stereochemistry; Biochemistry","score_opus":0.07076539575008657,"score_gpt":0.29460676795881735,"score_spread":0.2238413722087308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099927887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99584174,0.00031358833,0.000008583182,0.0030991766,0.000014428415,0.0002414148,0.000012698735,0.0000021125095,0.00046626],"genre_scores_gemma":[0.9973865,0.00007727052,0.0019198768,0.00043075735,0.000080208476,0.0000091792535,0.0000010101738,0.0000047846574,0.00009039467],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984215,0.00003183419,0.00037351937,0.0002953903,0.0006748309,0.00020291816],"domain_scores_gemma":[0.9994656,0.00005283783,0.00026750134,0.000024587203,0.00016466453,0.000024846358],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001426328,0.000120759694,0.00016747978,0.00010036841,0.00013377273,0.00003578432,0.0006303989,0.0000890932,0.000035975347],"category_scores_gemma":[0.00030417775,0.00007401228,0.0000718061,0.00060222385,0.00043798075,0.0000392144,0.00010238736,0.00014963107,4.901864e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036707777,0.00006390629,0.002951838,0.000022175198,0.000009292358,3.1190044e-8,0.00049009133,0.00017710462,0.9940109,0.0018238057,0.0003613965,0.00005275177],"study_design_scores_gemma":[0.00038901373,0.0003242577,0.023183506,0.000104083236,0.000015132044,0.000021095562,0.000625958,0.0062942277,0.9639248,0.0048445114,0.00015345492,0.00011995941],"about_ca_topic_score_codex":0.000030785835,"about_ca_topic_score_gemma":0.0000026619769,"teacher_disagreement_score":0.030086098,"about_ca_system_score_codex":0.00003113943,"about_ca_system_score_gemma":0.00003413891,"threshold_uncertainty_score":0.3018133},"labels":[],"label_agreement":null},{"id":"W2101090893","doi":"10.1517/14728222.2015.1042365","title":"Subcellular G-protein coupled receptor signaling hints at greater therapeutic selectivity","year":2015,"lang":"en","type":"editorial","venue":"Expert Opinion on Therapeutic Targets","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; McGill University; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Receptor; Subcellular localization; Cell biology; Signal transduction; Nucleus; Biology; Extracellular; Rhodopsin-like receptors; Cell surface receptor; Intracrine; Transmembrane protein; Cell; Functional selectivity; Cytoplasm; Biochemistry; Agonist; Paracrine signalling","score_opus":0.02336361581227873,"score_gpt":0.2816742498174154,"score_spread":0.25831063400513665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101090893","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007897659,0.116017565,0.0056083356,0.0003076436,0.8671836,0.002075878,0.00029090594,0.00025396256,0.0003644267],"genre_scores_gemma":[0.10638291,0.0064073936,0.0010584153,0.0011974137,0.8654822,0.0007569482,0.008941497,0.0008757437,0.008897463],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99471444,0.00059241295,0.00068985374,0.0016682775,0.0013666514,0.0009683361],"domain_scores_gemma":[0.997396,0.00010856681,0.0004970885,0.0010886517,0.00056111434,0.00034857442],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010614316,0.0011054069,0.00091446843,0.00016473098,0.0003958434,0.00013442483,0.00077344995,0.0020965163,0.0013366783],"category_scores_gemma":[0.00016571947,0.0009755999,0.00048410805,0.00016247007,0.00012192555,0.000013905464,0.00024451088,0.0008288007,0.00027536636],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009656839,0.00013737177,0.0000038461535,0.000027060765,0.00038842205,0.0000038699286,0.00028636723,0.000032893116,0.6712415,0.000019721176,0.32468292,0.0022102904],"study_design_scores_gemma":[0.0010084447,0.00092235167,5.8607293e-7,0.00009198739,0.000011840141,0.000002144752,0.00003756381,0.000101947146,0.38777202,0.00013227662,0.6091661,0.0007527467],"about_ca_topic_score_codex":0.00006124797,"about_ca_topic_score_gemma":0.0000065066843,"teacher_disagreement_score":0.28448316,"about_ca_system_score_codex":0.0004342368,"about_ca_system_score_gemma":0.00047689132,"threshold_uncertainty_score":0.9995762},"labels":[],"label_agreement":null},{"id":"W2101361999","doi":"10.1210/me.2004-0246","title":"c-Src Regulates Clathrin Adapter Protein 2 Interaction with β-Arrestin and the Angiotensin II Type 1 Receptor during Clathrin- Mediated Internalization","year":2004,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Clathrin; Internalization; Biology; Proto-oncogene tyrosine-protein kinase Src; Arrestin; Signal transducing adaptor protein; Cell biology; Adapter (computing); Receptor; Endocytosis; G protein-coupled receptor; Phosphorylation; Signal transduction; Biochemistry","score_opus":0.005403496396264049,"score_gpt":0.2064112307682178,"score_spread":0.20100773437195374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101361999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986178,0.001051686,0.0108893225,0.0011920996,0.00013260575,0.00042513726,0.0000025916795,0.000038528884,0.00009005733],"genre_scores_gemma":[0.9972813,0.00014187703,0.0017971898,0.00038103896,0.00012339759,0.00003600674,0.00007310703,0.000043337233,0.00012274548],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987224,0.00012009199,0.00024844045,0.00044769753,0.0001306619,0.00033070473],"domain_scores_gemma":[0.9993791,0.0000092613955,0.00013775221,0.000269775,0.00012864027,0.00007544493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008671907,0.00022977988,0.00021544374,0.000059374768,0.00015485482,0.000034468136,0.00015513644,0.0001463571,0.000058192483],"category_scores_gemma":[0.000092569055,0.00016614908,0.00006471653,0.00011799889,0.00018154374,0.000010692635,0.00019117449,0.00019492987,0.000009858877],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011511979,0.000025243631,0.000063540225,0.000011125226,0.00010198655,0.00003469873,0.00022176644,0.001437964,0.99468344,0.0018457662,0.000020210195,0.00040307525],"study_design_scores_gemma":[0.0031474004,0.0006645319,0.00010179384,0.00006528044,0.0000303157,0.00020458444,0.000105221065,0.00016712066,0.9917509,0.00032936034,0.0031972115,0.00023625961],"about_ca_topic_score_codex":0.00008804847,"about_ca_topic_score_gemma":0.000038189177,"teacher_disagreement_score":0.011103329,"about_ca_system_score_codex":0.000024097893,"about_ca_system_score_gemma":0.000038861384,"threshold_uncertainty_score":0.67753625},"labels":[],"label_agreement":null},{"id":"W2101785485","doi":"10.1016/j.clpt.2003.11.313","title":"Drug-disease interaction:effect of rheumatoid arthritis (RA) on the pharmacodynamics (PD) and pharmacokinetics (PK) of AT1 receptor antagonists","year":2004,"lang":"en","type":"article","venue":"Clinical Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Active metabolite; Rheumatoid arthritis; Pharmacokinetics; Pharmacology; Medicine; Losartan; Downregulation and upregulation; Pharmacodynamics; Valsartan; Angiotensin II receptor type 1; Arthritis; Metabolite; Internal medicine; Receptor; Endocrinology; Angiotensin II; Blood pressure; Chemistry","score_opus":0.02375094706231464,"score_gpt":0.3514826693637446,"score_spread":0.32773172230143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101785485","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910415,0.0030332338,0.00043942826,0.0027656911,0.002026677,0.00053118507,0.00008069175,0.000018548131,0.00006307687],"genre_scores_gemma":[0.95139116,0.04154765,0.00023517675,0.006274896,0.00039048513,0.000034418244,0.00004727923,0.000045516408,0.000033412733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976656,0.0005712985,0.000797522,0.00045797485,0.00020290297,0.00030471926],"domain_scores_gemma":[0.99845725,0.00046742638,0.00043325862,0.00029854005,0.00015200232,0.0001915063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00088213006,0.000308713,0.00047213899,0.00005380479,0.00012588002,0.000014514616,0.00034703797,0.00018837514,0.00020480291],"category_scores_gemma":[0.00004711884,0.00023629343,0.00029490495,0.00011779188,0.00060350803,0.000008307126,0.0001475001,0.00045497948,0.000009801336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027341046,0.0004857039,0.0009836934,0.000051806997,0.00069865905,0.0000067800433,0.00007744095,0.0007664743,0.98468274,0.000105791834,0.0024677452,0.006939086],"study_design_scores_gemma":[0.0043141167,0.0014511257,0.00013112045,0.00007908629,0.00020900807,0.0000105543595,0.000045960765,0.00059070234,0.9622561,0.0001352018,0.030530207,0.0002468484],"about_ca_topic_score_codex":0.000004415007,"about_ca_topic_score_gemma":0.0000015976265,"teacher_disagreement_score":0.039650302,"about_ca_system_score_codex":0.000021898391,"about_ca_system_score_gemma":0.00012175526,"threshold_uncertainty_score":0.9635766},"labels":[],"label_agreement":null},{"id":"W2101968602","doi":"10.1093/emboj/21.7.1628","title":"Ligands act as pharmacological chaperones and increase the efficiency of δ opioid receptor maturation","year":2002,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":261,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canada Research Chairs","keywords":"Endoplasmic reticulum; Receptor; Biology; Cell biology; Chaperone (clinical); G protein-coupled receptor; Opioid receptor; Signal transduction; ER retention; Chemical chaperone; Protein folding; Biochemistry; Unfolded protein response; Opioid","score_opus":0.012731393198246663,"score_gpt":0.24606439973503239,"score_spread":0.23333300653678574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2101968602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956798,0.002623029,0.00026061063,0.00067389983,0.00020517684,0.00008085203,0.0000018021079,0.0000029050975,0.00047191457],"genre_scores_gemma":[0.9964762,0.0023938403,0.00008922021,0.00026476744,0.00046191012,0.000002962685,0.0000021930016,0.000006261142,0.00030269971],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99941945,0.00008009358,0.00015817025,0.00009315312,0.00012357936,0.00012556196],"domain_scores_gemma":[0.99967283,0.000025751775,0.000110219014,0.00008802515,0.00004906662,0.000054082277],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042451455,0.0000806994,0.00008183765,0.00001431896,0.00024996666,0.000040806975,0.0001778688,0.000050345156,0.0007203428],"category_scores_gemma":[0.00006429997,0.000038802005,0.00005533806,0.000044793254,0.0000778507,0.0000049378136,0.000052665397,0.00014947933,0.000007519087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000766783,0.0000323874,0.00003982612,0.0000024013987,0.000025440297,0.0000011772422,0.00026609056,0.000015644202,0.99491817,0.00008365378,0.0012309403,0.0033075702],"study_design_scores_gemma":[0.0003862116,0.00042515976,0.00016021809,0.000012154029,0.000034559514,0.0002892537,0.00026370032,0.0005783509,0.9917748,0.0002646669,0.0057266583,0.00008425718],"about_ca_topic_score_codex":0.0000035584724,"about_ca_topic_score_gemma":3.850248e-7,"teacher_disagreement_score":0.0044957176,"about_ca_system_score_codex":0.000004403555,"about_ca_system_score_gemma":0.000015547517,"threshold_uncertainty_score":0.78872484},"labels":[],"label_agreement":null},{"id":"W2102284823","doi":"10.1016/j.bmc.2010.11.020","title":"3-[(Imidazolidin-2-yl)imino]indazole ligands with selectivity for the α2-adrenoceptor compared to the imidazoline I1 receptor","year":2010,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Imidazoline receptor; Selectivity; Indazole; Clonidine; Ligand (biochemistry); Stereochemistry; Adrenergic receptor; Agonist; Receptor; Pharmacology; Endocrinology; Biochemistry","score_opus":0.008582338098737385,"score_gpt":0.23385712604422923,"score_spread":0.22527478794549186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102284823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876274,0.00053990015,0.006424583,0.003610439,0.00071474124,0.0007281531,0.0000844423,0.000050531926,0.00021980175],"genre_scores_gemma":[0.99327415,0.00005897028,0.0008688582,0.0008231617,0.0037593355,0.00017118537,0.00017507741,0.000080715676,0.0007885294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978497,0.000023901464,0.00036527813,0.00070118,0.00043172587,0.00062821375],"domain_scores_gemma":[0.99820405,0.000120939054,0.0001902832,0.00086369424,0.00030843672,0.00031260803],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00073079776,0.00042651064,0.0003485287,0.000023501754,0.0005409342,0.00008008336,0.00087963184,0.0003162412,0.0009531461],"category_scores_gemma":[0.00032973682,0.00024435925,0.00015709635,0.00027676014,0.00020743998,0.0000072871335,0.00017044942,0.00053313456,0.000024724957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004130092,0.00007553885,0.00019890316,0.0000419953,0.00012370359,0.0000012130528,0.00018090381,0.000021198692,0.9842405,0.000016250935,0.013078309,0.0016084734],"study_design_scores_gemma":[0.0009495989,0.00022306503,0.0002538054,0.00003139926,0.000102788996,0.000074207004,0.0004936578,0.0001397619,0.901241,0.0000137449215,0.09613487,0.00034212042],"about_ca_topic_score_codex":0.00003618743,"about_ca_topic_score_gemma":0.000095792326,"teacher_disagreement_score":0.08305656,"about_ca_system_score_codex":0.000037773498,"about_ca_system_score_gemma":0.0003379792,"threshold_uncertainty_score":0.9999601},"labels":[],"label_agreement":null},{"id":"W2102308209","doi":"10.1161/circheartfailure.112.966705","title":"Agonist-Induced Hypertrophy and Diastolic Dysfunction Are Associated With Selective Reduction in Glucose Oxidation","year":2012,"lang":"en","type":"article","venue":"Circulation Heart Failure","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Endocrinology; Internal medicine; Pyruvate dehydrogenase complex; Angiotensin II; Beta oxidation; Muscle hypertrophy; Chemistry; Biology; Medicine; Receptor; Biochemistry; Metabolism; Enzyme","score_opus":0.011780183152925037,"score_gpt":0.21786440908788607,"score_spread":0.20608422593496104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102308209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979691,0.00014870291,0.0012686538,0.0001674872,0.00010465179,0.00029633573,0.0000020313537,0.000018463617,0.000024585817],"genre_scores_gemma":[0.99915284,0.0000068281925,0.0003079548,0.0000467841,0.00022806405,0.000047675476,0.00016992123,0.000019254061,0.000020674393],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992292,0.00009610435,0.00013626942,0.00023143293,0.0001123358,0.00019467477],"domain_scores_gemma":[0.9996275,0.000007814918,0.0000950215,0.000106736436,0.00009694235,0.000066025656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001720898,0.000118135016,0.00011810164,0.00007372159,0.00011101544,0.000025920084,0.0000219467,0.00017427426,0.000014919054],"category_scores_gemma":[0.000062593994,0.00011471529,0.000028610639,0.00018628794,0.00001730922,0.000031182994,0.000011695247,0.00009757065,0.0000036292336],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036542635,0.00004941421,0.04094733,0.0000052512532,0.000018116018,1.6213612e-7,0.00012386969,0.00023005968,0.9578423,0.000033782177,0.00008206448,0.0006310897],"study_design_scores_gemma":[0.00085297856,0.00019740073,0.4058295,0.000053896892,0.000024569064,0.000038699825,0.0004214389,0.00034384153,0.590716,0.000049693812,0.0012128033,0.00025915244],"about_ca_topic_score_codex":0.000030047337,"about_ca_topic_score_gemma":0.000051882413,"teacher_disagreement_score":0.3671263,"about_ca_system_score_codex":0.00005847219,"about_ca_system_score_gemma":0.000027432907,"threshold_uncertainty_score":0.46779534},"labels":[],"label_agreement":null},{"id":"W2102459914","doi":"10.1016/j.cell.2015.04.043","title":"Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling","year":2015,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":679,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institute of Neurological Disorders and Stroke; National Eye Institute","keywords":"Biology; Signal transduction; Process (computing); Receptor; Cell biology; Computational biology; Genetics; Computer science","score_opus":0.009433383656503777,"score_gpt":0.2369940293657141,"score_spread":0.2275606457092103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2102459914","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956994,0.002402497,0.00082132936,0.000023648363,0.00029145108,0.000099040444,0.0000016024891,0.000007746665,0.0006532885],"genre_scores_gemma":[0.99860686,0.000046314282,0.00062436925,0.00005747024,0.00013664635,0.0000080080945,0.00005759839,0.000018250317,0.0004444531],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992659,0.000048835667,0.00018154725,0.00021202776,0.00014750366,0.00014416539],"domain_scores_gemma":[0.99945384,0.0000076355445,0.00010488632,0.00021941337,0.00014028246,0.00007396488],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001303174,0.000121162484,0.000118457174,0.000023062059,0.000065804554,0.000016156495,0.00024822543,0.00010226304,0.00005267253],"category_scores_gemma":[0.000024973342,0.0000806552,0.000063996515,0.000085060456,0.000054969827,0.0000039002293,0.0000599612,0.00007324747,0.0000075194916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030817813,0.0000103015445,0.000035000117,0.000020757543,0.00001181357,4.326724e-7,0.0011492083,0.0018835863,0.99625605,0.000041288786,0.000105757965,0.0004549548],"study_design_scores_gemma":[0.00028157278,0.00015313328,0.000007729293,0.00001026918,0.000010557379,0.0000013350424,0.0010549146,0.001246564,0.99380124,0.00091795385,0.002392161,0.00012258117],"about_ca_topic_score_codex":0.000021233203,"about_ca_topic_score_gemma":0.0000114391105,"teacher_disagreement_score":0.0029074939,"about_ca_system_score_codex":0.000011708325,"about_ca_system_score_gemma":0.00008933253,"threshold_uncertainty_score":0.32890236},"labels":[],"label_agreement":null},{"id":"W2103897720","doi":"10.1124/mol.106.022897","title":"Simultaneous Activation of the δ Opioid Receptor (δOR)/Sensory Neuron-Specific Receptor-4 (SNSR-4) Hetero-Oligomer by the Mixed Bivalent Agonist Bovine Adrenal Medulla Peptide 22 Activates SNSR-4 but Inhibits δOR Signaling","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Drug Abuse","keywords":"Agonist; Receptor; Adenylyl cyclase; Cell biology; Chemistry; Signal transduction; G protein-coupled receptor; Functional selectivity; HEK 293 cells; Biochemistry; Biophysics; Biology","score_opus":0.007928825530473521,"score_gpt":0.2293944132220894,"score_spread":0.22146558769161587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103897720","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992016,0.0016288616,0.0029308477,0.0007611718,0.0014033106,0.0008838849,0.00015101224,0.000042748394,0.00018215312],"genre_scores_gemma":[0.99558616,0.00031855653,0.0004915154,0.0010197646,0.00076414546,0.00010508856,0.0003961936,0.00012159192,0.0011969793],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962838,0.000775856,0.0007850517,0.0008850443,0.0005286959,0.00074151414],"domain_scores_gemma":[0.9982071,0.00019859977,0.00058124564,0.000579649,0.00029052625,0.00014288802],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000401525,0.0005709971,0.0004684524,0.00009976642,0.0004444609,0.00007094026,0.000754614,0.00037903746,0.00072938815],"category_scores_gemma":[0.00009944877,0.00043118795,0.0004138506,0.00030511353,0.0003715739,0.00001806764,0.00034329214,0.00052205735,0.00002585017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052648544,0.00025142016,0.00004680982,0.000040243398,0.00018621836,0.000009028342,0.00005315253,0.005050581,0.97407323,0.000053147534,0.018458923,0.0012507514],"study_design_scores_gemma":[0.0012035134,0.00039854093,0.00001938999,0.000034536813,0.000078285986,0.000028084456,0.00010249802,0.00029355384,0.9055065,0.00004250637,0.09186947,0.00042314644],"about_ca_topic_score_codex":0.00009777343,"about_ca_topic_score_gemma":0.000004907031,"teacher_disagreement_score":0.07341055,"about_ca_system_score_codex":0.00010234959,"about_ca_system_score_gemma":0.00012930854,"threshold_uncertainty_score":0.999814},"labels":[],"label_agreement":null},{"id":"W2104096459","doi":"10.1161/hypertensionaha.111.175208","title":"Agonist-Independent Constitutive Activity of Angiotensin II Receptor Promotes Cardiac Remodeling in Mice","year":2012,"lang":"en","type":"article","venue":"Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital; University of Ottawa","funders":"","keywords":"Angiotensin II; Agonist; Receptor; Renin–angiotensin system; Internal medicine; Ventricular remodeling; Endocrinology; Heart failure; Angiotensin II receptor type 1; Medicine; Pharmacology; Chemistry; Cardiology; Blood pressure","score_opus":0.02037377512888372,"score_gpt":0.23480428818861934,"score_spread":0.21443051305973562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2104096459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966251,0.0013396243,0.0009435935,0.00006555925,0.00048544223,0.00020795099,0.00001383122,0.00000896604,0.00030991],"genre_scores_gemma":[0.99630105,0.0001510351,0.003155048,0.00006274081,0.0001932478,0.000005250493,0.000039917213,0.000017142012,0.000074568045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990273,0.0000880344,0.00019072196,0.0002601257,0.0001509082,0.000282909],"domain_scores_gemma":[0.99949014,0.000013733716,0.000091854075,0.00019627964,0.00012805736,0.000079956924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037890254,0.00014571876,0.0002567694,0.00005112648,0.00008768844,0.000006297666,0.00007521093,0.00019796459,0.000016161708],"category_scores_gemma":[0.00009314531,0.00013173166,0.00011531481,0.00007956491,0.000049879785,0.000011369928,0.00012038815,0.00010988401,0.0000054233146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009310332,0.00012423,0.00068063906,0.000009265862,0.00002273253,8.663913e-7,0.000106580446,0.000045290337,0.99573207,0.000061974235,0.00027603988,0.0028472135],"study_design_scores_gemma":[0.00029276943,0.00013411732,0.000611207,0.000053365904,0.000020074016,0.000011601864,0.00010247316,0.00036164708,0.99489844,0.000016685075,0.0033308007,0.00016680657],"about_ca_topic_score_codex":0.00012495462,"about_ca_topic_score_gemma":0.000007849619,"teacher_disagreement_score":0.0030547609,"about_ca_system_score_codex":0.000022836393,"about_ca_system_score_gemma":0.000058212565,"threshold_uncertainty_score":0.53718615},"labels":[],"label_agreement":null},{"id":"W2105330325","doi":"10.1172/jci16100","title":"The α1A/C- and α1B-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse","year":2003,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":185,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, San Francisco; National Heart, Lung, and Blood Institute; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Heart and Stroke Foundation of Canada; American Heart Association; National Institutes of Health; National Science Foundation","keywords":"Internal medicine; Endocrinology; Muscle hypertrophy; Myocyte; Heart rate; Pressure overload; Cardiac function curve; Receptor; Knockout mouse; Stimulation; Biology; Cardiac myocyte; Genetically modified mouse; Blood pressure; Medicine; Heart failure; Cardiac hypertrophy; Transgene","score_opus":0.08104296557997151,"score_gpt":0.3382082378545646,"score_spread":0.25716527227459307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105330325","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99698305,0.0010607729,0.00034581276,0.0007825888,0.0006006778,0.00018084572,0.0000020483274,0.000001964505,0.000042267457],"genre_scores_gemma":[0.9958785,0.0011823593,0.0014826012,0.00061618217,0.00067502336,0.00001481824,0.000008643733,0.000010768744,0.00013109444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827737,0.00050207315,0.00073664734,0.00016916197,0.00016117771,0.00015356697],"domain_scores_gemma":[0.9987945,0.00027946397,0.00052442413,0.00015747396,0.00015352125,0.0000906078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0027666078,0.000108002234,0.0002646356,0.000020491332,0.00013864307,0.000052518903,0.00017556534,0.00019467206,0.0000040847294],"category_scores_gemma":[0.0014357871,0.000055991375,0.00022579348,0.00007014343,0.0001692543,0.00001027369,0.000019720996,0.00021817349,6.5015166e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009962963,0.0001387087,0.008703489,0.000023386434,0.00015763659,0.0000034214188,0.00017364352,0.00071250164,0.96628004,0.008461929,0.009457502,0.0048914384],"study_design_scores_gemma":[0.008168214,0.005408153,0.018538382,0.00015401925,0.00021552191,0.00005395813,0.002294604,0.00051142025,0.75596416,0.036025494,0.17196724,0.0006988252],"about_ca_topic_score_codex":0.0000022670647,"about_ca_topic_score_gemma":0.0000033530212,"teacher_disagreement_score":0.21031587,"about_ca_system_score_codex":0.000007531282,"about_ca_system_score_gemma":0.000077002995,"threshold_uncertainty_score":0.2283262},"labels":[],"label_agreement":null},{"id":"W2105331656","doi":"10.1002/open.201300040","title":"<i>N</i>‐Aryl Isoleucine Derivatives as Angiotensin II AT<sub>2</sub> Receptor Ligands","year":2014,"lang":"en","type":"article","venue":"ChemistryOpen","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Vetenskapsrådet; Alzheimer Society; Canadian Diabetes Association","keywords":"Aryl; Isoleucine; Chemistry; Angiotensin II; Combinatorial chemistry; Stereochemistry; Receptor; Organic chemistry; Amino acid; Biochemistry","score_opus":0.005915679718221901,"score_gpt":0.21226440501852392,"score_spread":0.20634872530030202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105331656","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941009,0.0004080983,0.00070644607,0.0004115722,0.0001908901,0.00015796912,0.000014823068,0.00003884482,0.0039704363],"genre_scores_gemma":[0.9940777,0.00019106088,0.0005909145,0.00075147906,0.0008610201,0.000029421482,0.0004445829,0.00006174427,0.0029920884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984154,0.000020512645,0.00029774735,0.0006498425,0.00019814567,0.00041834108],"domain_scores_gemma":[0.9989119,0.000017069973,0.00015039204,0.00057507574,0.0001297424,0.00021577349],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025995533,0.0003179984,0.00029662476,0.000022796456,0.00029973878,0.000046948073,0.0003704314,0.0002973186,0.00037999245],"category_scores_gemma":[0.00019919313,0.0003071397,0.00017010163,0.000110048546,0.00009242397,0.000007950794,0.0004946531,0.00013548713,0.0001272758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010166968,0.000045829613,0.00011911689,0.000020447342,0.0000547536,0.0000017714885,0.00006636216,0.000012244337,0.98005235,0.00003108896,0.017487515,0.0020068744],"study_design_scores_gemma":[0.0006329566,0.0002537822,0.0000522452,0.00004319439,0.00001789014,0.000025579368,0.00003529928,0.00003425707,0.90958524,0.00009881661,0.08884155,0.0003792172],"about_ca_topic_score_codex":0.000007579208,"about_ca_topic_score_gemma":0.0000034193122,"teacher_disagreement_score":0.07135403,"about_ca_system_score_codex":0.0000334076,"about_ca_system_score_gemma":0.00006283615,"threshold_uncertainty_score":0.9999381},"labels":[],"label_agreement":null},{"id":"W2105840785","doi":"10.1074/jbc.m306451200","title":"Adenosine A2A-Dopamine D2 Receptor-Receptor Heteromerization","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":427,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"European Commission; European Molecular Biology Laboratory","keywords":"Dopamine receptor D2; Chemistry; Dopamine receptor D1; Receptor; Adenosine; Dopamine; Dopamine receptor; Adenosine receptor; Cell biology; Biology; Endocrinology; Biochemistry; Agonist","score_opus":0.015702547935684024,"score_gpt":0.2378975572866543,"score_spread":0.22219500935097028,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105840785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99266446,0.0014991661,0.004433166,0.000093053,0.00035206278,0.000060216254,0.00001202429,0.000008980682,0.0008768452],"genre_scores_gemma":[0.9938738,0.00074760907,0.0037979488,0.00013629884,0.0007208787,0.0000034923282,0.00009125559,0.000019263192,0.0006094674],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986893,0.00008791753,0.0005206709,0.000254214,0.00018857581,0.0002593031],"domain_scores_gemma":[0.9990231,0.000021613709,0.00039049613,0.00017981876,0.0002070194,0.0001779967],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00039739523,0.00020770135,0.000295157,0.000023575649,0.000068753056,0.000029687737,0.0002397818,0.00032519278,0.0017890984],"category_scores_gemma":[0.0004812114,0.00015353144,0.00022591527,0.000109443885,0.00007524892,0.0000073495103,0.000043472137,0.00022039778,0.000014494206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097241114,0.00010412126,0.00091580313,0.000014433371,0.000049572896,0.0000042291085,0.0000064193177,0.00003043627,0.99676,0.000023715987,0.001343441,0.00065059704],"study_design_scores_gemma":[0.0005199814,0.00044877073,0.000072501956,0.000024778818,0.000010807869,0.000115908486,0.00006419604,0.0000032272364,0.91512376,0.00005922644,0.083370544,0.0001863124],"about_ca_topic_score_codex":4.148486e-7,"about_ca_topic_score_gemma":5.832714e-8,"teacher_disagreement_score":0.0820271,"about_ca_system_score_codex":0.00002805195,"about_ca_system_score_gemma":0.00006053463,"threshold_uncertainty_score":0.9991234},"labels":[],"label_agreement":null},{"id":"W2106099541","doi":"10.1677/joe.0.1740017","title":"Failed export of the adrenocorticotrophin receptor from the endoplasmic reticulum in non-adrenal cells: evidence in support of a requirement for a specific adrenal accessory factor","year":2002,"lang":"en","type":"article","venue":"Journal of Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; University of Toronto; National Institutes of Health; Queen Mary University of London","keywords":"KDEL; Transfection; Endoplasmic reticulum; Green fluorescent protein; Receptor; Melanocortin; ACTH receptor; Biology; Cell biology; Cell culture; Adrenocorticotropic hormone; Molecular biology; Endocrinology; Hormone; Gene; Biochemistry","score_opus":0.049093227459971085,"score_gpt":0.26712313661767556,"score_spread":0.21802990915770448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106099541","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99629194,0.0015641248,0.0006125717,0.00043529438,0.00063256425,0.0003744812,0.000047166075,0.000001260379,0.000040628052],"genre_scores_gemma":[0.9963611,0.0019940862,0.0011787569,0.00010230003,0.00025551065,0.000022604201,0.0000048434667,0.000017872624,0.00006294831],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977445,0.00018375425,0.001175329,0.00025977785,0.00027363695,0.00036301388],"domain_scores_gemma":[0.99826664,0.00016676323,0.0009635053,0.00036116177,0.00018909901,0.000052857296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029906983,0.00018647246,0.00046214665,0.00011125042,0.000034927067,0.000011800743,0.0006752225,0.00012618041,0.00069585815],"category_scores_gemma":[0.00024407038,0.00011848184,0.0002897269,0.000142655,0.00014595724,0.000019193538,0.00014589701,0.00029198988,0.0000018118707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042312694,0.00015397654,0.009082467,0.000020740514,0.00006817444,0.000017153365,0.00033395208,0.00012718418,0.98684555,0.00003025465,0.0018328789,0.0010645505],"study_design_scores_gemma":[0.0016703791,0.00097106496,0.0075110397,0.00016032638,0.000028156732,0.000047878155,0.00024313384,0.00006037195,0.9859999,0.00010008314,0.0030845827,0.00012311977],"about_ca_topic_score_codex":0.000040021896,"about_ca_topic_score_gemma":0.00006909876,"teacher_disagreement_score":0.0015714274,"about_ca_system_score_codex":0.00004366061,"about_ca_system_score_gemma":0.00010740768,"threshold_uncertainty_score":0.76191586},"labels":[],"label_agreement":null},{"id":"W2106429495","doi":"10.1371/journal.pone.0082164","title":"Broad-Scale Phosphoprotein Profiling of Beta Adrenergic Receptor (β-AR) Signaling Reveals Novel Phosphorylation and Dephosphorylation Events","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital","funders":"Canadian Institutes of Health Research; U.S. Public Health Service; National Institutes of Health; Donald E. and Delia B. Baxter Foundation; Lupus Research Alliance; National Institute of Allergy and Infectious Diseases; European Commission; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Dephosphorylation; Phosphorylation; CREB; Signal transduction; Biology; Forskolin; Adenylyl cyclase; Cell biology; Protein kinase B; Activator (genetics); Phosphatase; Receptor; Biochemistry; Transcription factor","score_opus":0.018051500307274364,"score_gpt":0.2066650981026685,"score_spread":0.18861359779539413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106429495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918995,0.0015359758,0.00553033,0.000039616116,0.00005619522,0.000780258,0.000022479728,0.000021763859,0.00011387876],"genre_scores_gemma":[0.9464,0.00022685179,0.052425075,0.00004920906,0.00013726161,0.00011886838,0.00020894126,0.00004364571,0.00039014526],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843884,0.000046267993,0.00046350085,0.000452097,0.00032381574,0.0002754564],"domain_scores_gemma":[0.99903226,0.000019447936,0.0002837354,0.00027832796,0.0002713385,0.00011486193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030665318,0.00021811925,0.00030754154,0.000056030254,0.00010592409,0.000028974831,0.00014146754,0.00023090551,0.00030133966],"category_scores_gemma":[0.00006788998,0.00022171595,0.00008059896,0.00013203804,0.000040314175,0.000023401773,0.00008981644,0.0001137333,0.000015508082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005807295,0.0003085645,0.005968081,0.00009666492,0.000121833385,8.300357e-8,0.00006669724,0.000085220076,0.99200815,0.00008180107,0.000018329618,0.0011865201],"study_design_scores_gemma":[0.00059480785,0.0002543555,0.0011021383,0.00020539209,0.00006335179,8.8990987e-7,0.00008464585,0.00083248015,0.9963495,0.00023971715,0.000018895296,0.00025383965],"about_ca_topic_score_codex":0.00011369796,"about_ca_topic_score_gemma":0.0000040008763,"teacher_disagreement_score":0.046894748,"about_ca_system_score_codex":0.00002175662,"about_ca_system_score_gemma":0.00003818684,"threshold_uncertainty_score":0.9041314},"labels":[],"label_agreement":null},{"id":"W2106506889","doi":"10.1111/bph.12695","title":"Analgesic synergy between opioid and α<sub>2</sub>‐adrenoceptors","year":2014,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Opioid; Analgesic; Pharmacology; Medicine; Agonist; Functional selectivity; Drug; Neuroscience; Receptor; Opioid receptor; Psychology; Internal medicine","score_opus":0.014567323959111424,"score_gpt":0.2932768069154771,"score_spread":0.27870948295636566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106506889","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.022678293,0.9750494,0.0007769278,0.000012946678,0.0011912534,0.0001960699,0.00005195985,0.0000061249684,0.000037045735],"genre_scores_gemma":[0.00612915,0.9893323,0.00018683834,0.000121382654,0.003979709,0.000011829638,0.0001061873,0.00008053803,0.00005204246],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974875,0.0005023269,0.0010141185,0.0004042621,0.00019439885,0.00039739083],"domain_scores_gemma":[0.99833626,0.00008645059,0.001049627,0.00009517254,0.00017641134,0.0002561073],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007551913,0.00037443027,0.0016442594,0.00018290394,0.000119425604,0.00006997383,0.00043232003,0.0006022568,0.00018665739],"category_scores_gemma":[0.00006729395,0.0003945329,0.00058651733,0.00012034432,0.00012113748,0.000007867094,0.00017391384,0.000629969,0.000008221481],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000131285515,0.000025408988,0.000002596473,0.0013577039,0.0007300876,0.00014010904,0.0000053558097,0.0000020143445,0.055245526,0.0000052344035,0.01310201,0.9293708],"study_design_scores_gemma":[0.00058067695,0.00048361754,0.000004190249,0.0017689725,0.0013174108,0.003545216,0.000006033526,9.409262e-7,0.056405496,0.000037348404,0.93545276,0.00039732317],"about_ca_topic_score_codex":0.0000065403033,"about_ca_topic_score_gemma":0.0000035343169,"teacher_disagreement_score":0.9289735,"about_ca_system_score_codex":0.000037276517,"about_ca_system_score_gemma":0.00029193689,"threshold_uncertainty_score":0.99985063},"labels":[],"label_agreement":null},{"id":"W2106743210","doi":"10.1124/mol.115.098897","title":"A Perspective on Studying G-Protein–Coupled Receptor Signaling with Resonance Energy Transfer Biosensors in Living Organisms","year":2015,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute on Drug Abuse","keywords":"G protein-coupled receptor; Förster resonance energy transfer; Biosensor; Cell biology; Biology; In vivo; Computational biology; Signal transduction; Living cell; Receptor; Biochemistry; Biotechnology; Physics; Fluorescence","score_opus":0.02434166380676032,"score_gpt":0.30519863735378294,"score_spread":0.2808569735470226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106743210","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016145932,0.977951,0.0037831531,0.00004239353,0.00038790808,0.0013390144,0.00003471021,0.000048572467,0.00026733792],"genre_scores_gemma":[0.027869418,0.96754766,0.0012563491,0.0005799487,0.0006770926,0.00086336833,0.0001683945,0.00044881654,0.0005889568],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954955,0.0010508943,0.00070674357,0.0015024423,0.00042014552,0.00082428125],"domain_scores_gemma":[0.9987282,0.00006932637,0.00022724239,0.00045960612,0.00027394173,0.00024169344],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007072185,0.00092578173,0.0016199525,0.00038297576,0.00012459746,0.000050952505,0.00058999326,0.00077620463,0.0003540125],"category_scores_gemma":[0.00007407597,0.0008044452,0.00039062108,0.00058388023,0.000120905344,0.000007906349,0.00016228433,0.000696459,0.000026624219],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000309758,0.0003875756,7.9716574e-7,0.0007398651,0.000713495,0.00041863456,0.00034377928,0.00027485617,0.9542206,0.0007750536,0.0002046926,0.041610897],"study_design_scores_gemma":[0.00166234,0.002030307,1.2704524e-7,0.0040434217,0.0005861267,0.00007524248,0.0004106955,0.000057828103,0.3241435,0.000039074308,0.6654305,0.0015208339],"about_ca_topic_score_codex":0.0000837846,"about_ca_topic_score_gemma":0.0000236471,"teacher_disagreement_score":0.6652258,"about_ca_system_score_codex":0.0004316054,"about_ca_system_score_gemma":0.0006909473,"threshold_uncertainty_score":0.99944067},"labels":[],"label_agreement":null},{"id":"W2107519125","doi":"10.1016/s0306-9877(02)00449-8","title":"Mathematical analysis of a pharmacodynamic model without plasma concentrations to extend its applicability","year":2003,"lang":"en","type":"article","venue":"Medical Hypotheses","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Sistema Nacional de Investigadores; Hospital for Sick Children; Instituto Mexicano del Seguro Social","keywords":"Pharmacodynamics; Reversion; Plasma concentration; Potency; Plasma; Chemistry; Therapeutic index; Elimination rate constant; Pharmacokinetics; Internal medicine; Drug; Pharmacology; Physics; Medicine; Biochemistry; Nuclear physics; In vitro","score_opus":0.023911985292172967,"score_gpt":0.3062603808916438,"score_spread":0.28234839559947084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107519125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7487766,0.00006497827,0.24963221,0.00005895853,0.000021992839,0.00015900553,0.000026468868,0.000007935725,0.0012518688],"genre_scores_gemma":[0.9936013,0.000033358072,0.005837237,0.0002103036,0.000025003614,0.000045906418,0.000015474743,0.000011979715,0.00021939685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880403,0.00007653265,0.00029742022,0.00028660754,0.00033530968,0.00020010068],"domain_scores_gemma":[0.99934375,0.00005908317,0.000052685074,0.00022733472,0.000070736314,0.00024641003],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041225922,0.000117183066,0.00027727464,0.0000547073,0.000042899275,0.000008917159,0.00016807506,0.00011972642,0.0012690382],"category_scores_gemma":[0.0008194527,0.00009556581,0.00014686052,0.000225287,0.00007315406,0.0000024022238,0.0000368073,0.00007239133,0.0000107985325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004682334,0.0002887731,0.00050873845,0.00003190689,0.00042001696,0.0000014564919,0.00011221202,0.0058866516,0.9813855,0.009506296,0.0000796772,0.0017319295],"study_design_scores_gemma":[0.00037929896,0.000102629645,0.000058004174,0.000018757532,0.0003301312,0.0000048183706,0.00008470302,0.31310117,0.6831521,0.0012970791,0.0012774948,0.00019385408],"about_ca_topic_score_codex":0.000002020301,"about_ca_topic_score_gemma":0.000010090996,"teacher_disagreement_score":0.30721453,"about_ca_system_score_codex":0.000010082335,"about_ca_system_score_gemma":0.00010658007,"threshold_uncertainty_score":0.9996439},"labels":[],"label_agreement":null},{"id":"W2107819770","doi":"10.1016/j.jmb.2012.05.029","title":"Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin","year":2012,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; National Institute on Drug Abuse; Gordon and Betty Moore Foundation","keywords":"Cytochrome P450; Chemistry; Heme; Biophysics; Dopamine; Ligand (biochemistry); Nuclear magnetic resonance; Biochemistry; Biology; Neuroscience; Enzyme; Receptor","score_opus":0.005729103505361029,"score_gpt":0.25013027598361365,"score_spread":0.24440117247825263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107819770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9426045,0.017104117,0.039776087,0.000075101736,0.00017587391,0.0002091113,0.000032328335,0.0000046660894,0.000018239156],"genre_scores_gemma":[0.9810974,0.00005698417,0.018526973,0.00007588094,0.00017862862,0.0000057301095,0.000022711327,0.000021494474,0.000014222188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889094,0.00016838008,0.0003944393,0.00017768277,0.0000906543,0.00027789728],"domain_scores_gemma":[0.99892455,0.00003450558,0.00035802537,0.00013003682,0.00046052682,0.000092379734],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003597146,0.00015902599,0.00028491655,0.00011461896,0.000044792476,0.0000066316243,0.000112308786,0.00015251763,0.000010771912],"category_scores_gemma":[0.00026528724,0.00013588717,0.00011262858,0.00011520056,0.00008625756,0.0000066595176,0.000032158012,0.000103895494,1.274827e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024540332,0.0000338012,0.0052061174,0.00001871435,0.000031999123,0.0000018785809,0.000019523197,0.00010452038,0.99201316,0.0002832082,0.00008717407,0.0019545055],"study_design_scores_gemma":[0.0012462292,0.0008498438,0.003829571,0.000026645881,0.000055326593,0.00012033865,0.000027961978,0.00045804822,0.9908773,0.00042427145,0.0019367755,0.00014772097],"about_ca_topic_score_codex":0.000011047634,"about_ca_topic_score_gemma":0.0000020522596,"teacher_disagreement_score":0.0384929,"about_ca_system_score_codex":0.000032796543,"about_ca_system_score_gemma":0.00009836958,"threshold_uncertainty_score":0.5541318},"labels":[],"label_agreement":null},{"id":"W2107871391","doi":"10.1002/0471142301.ns0523s34","title":"Monitoring Protein‐Protein Interactions in Living Cells by Bioluminescence Resonance Energy Transfer (<scp>BRET</scp>)","year":2006,"lang":"en","type":"article","venue":"Current Protocols in Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Bioluminescence; Luciferase; Green fluorescent protein; Förster resonance energy transfer; Chemistry; Energy transfer; Biophysics; Protein–protein interaction; G protein-coupled receptor; Cell biology; Receptor; Fluorescence; Biochemistry; Transfection; Biology; Physics","score_opus":0.022524147514465555,"score_gpt":0.29130505265156686,"score_spread":0.2687809051371013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107871391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9606587,0.0006175895,0.024065772,0.000014800469,0.0005179867,0.013934277,0.000017070175,0.00003078557,0.0001430033],"genre_scores_gemma":[0.96626073,0.00004877372,0.00023480451,0.000018962395,0.00018647687,0.032677326,0.000003832136,0.000025787216,0.0005433248],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997773,0.00014206416,0.00044975537,0.0008144401,0.0002765471,0.00054418866],"domain_scores_gemma":[0.99943256,0.000025814596,0.0000865025,0.00032432016,0.00005143698,0.000079371355],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003176267,0.0002523008,0.00018385959,0.00011759558,0.00012373376,0.00011567191,0.0005228696,0.000082300015,0.000004415547],"category_scores_gemma":[0.00015922562,0.0002592127,0.00006921315,0.0005086572,0.00011727947,0.000044561,0.00012610496,0.00027217524,0.000001918282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007712102,0.00024096244,0.0034367999,0.000040679868,2.7037726e-7,0.0000031001225,0.000021836235,0.000080464844,0.99305797,0.0001639014,0.00009102032,0.0028552818],"study_design_scores_gemma":[0.00024693922,0.0001296367,0.0012549742,0.00084310415,7.431922e-7,0.0000025425472,0.000014669402,0.0003530768,0.9516903,0.00006980878,0.04525274,0.00014144728],"about_ca_topic_score_codex":0.000094605646,"about_ca_topic_score_gemma":0.0000357035,"teacher_disagreement_score":0.04516172,"about_ca_system_score_codex":0.00004542776,"about_ca_system_score_gemma":0.00008220116,"threshold_uncertainty_score":0.999986},"labels":[],"label_agreement":null},{"id":"W2108078547","doi":"10.1091/mbc.e06-02-0097","title":"Dynamic Regulation of Mammalian Numb by G Protein-coupled Receptors and Protein Kinase C Activation: Structural Determinants of Numb Association with the Cortical Membrane","year":2006,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"NUMB; Biology; Cell biology; Phosphorylation; Membrane protein; Proto-oncogene tyrosine-protein kinase Src; Vesicle-associated membrane protein 8; Endocytic cycle; G protein-coupled receptor; Biochemistry; Endocytosis; Signal transduction; Receptor; Membrane","score_opus":0.00228079605081479,"score_gpt":0.1993735507288799,"score_spread":0.1970927546780651,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108078547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99692875,0.00012542067,0.0021699623,0.00015201708,0.000036286296,0.000530552,0.000016306316,0.000002886156,0.000037816415],"genre_scores_gemma":[0.9984832,0.00000279813,0.00093822146,0.000013405347,0.000013777185,0.000011883899,0.000063418905,0.000014264437,0.00045905373],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990337,0.00019746339,0.0002743881,0.00020913912,0.00013521448,0.00015007761],"domain_scores_gemma":[0.9991722,0.000013873361,0.00043816568,0.00023912273,0.000117283824,0.000019314415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023739536,0.00013174102,0.00019467976,0.000023906681,0.00006994876,0.0000052621085,0.00016467234,0.00020282349,0.000019647814],"category_scores_gemma":[0.000044937195,0.00008153567,0.00007281856,0.00010174566,0.00016701355,0.0000040963064,0.000057956913,0.00008715357,1.5550994e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012361028,0.000025241823,0.0024015699,0.000042782765,0.000024428478,1.4283516e-7,0.000016536662,0.00008909631,0.9970169,0.000140554,0.000013677216,0.000105480496],"study_design_scores_gemma":[0.00048183702,0.00029356254,0.001693911,0.00002815173,0.000028679819,0.0000017516487,0.000028643528,0.0005616307,0.99642074,0.0002987189,0.00006559299,0.00009676492],"about_ca_topic_score_codex":0.00010467642,"about_ca_topic_score_gemma":0.000024671031,"teacher_disagreement_score":0.001554424,"about_ca_system_score_codex":0.000017566663,"about_ca_system_score_gemma":0.000034508525,"threshold_uncertainty_score":0.3324928},"labels":[],"label_agreement":null},{"id":"W2108611680","doi":"10.1177/1947601912473603","title":"Overexpression of CD99 Increases the Migration and Invasiveness of Human Malignant Glioma Cells","year":2012,"lang":"en","type":"article","venue":"Genes & Cancer","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"CD99; Glioma; Cancer research; Biology; Pathology; Cell biology; Medicine; Stem cell","score_opus":0.014885085665003059,"score_gpt":0.2638853183193993,"score_spread":0.24900023265439625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108611680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98906183,0.010583359,0.00013301153,0.000009607466,0.000077556644,0.00008610783,0.000021841679,0.000001480849,0.000025173174],"genre_scores_gemma":[0.9987346,0.00089577853,0.0000903555,0.00002755289,0.00016396654,0.000017010912,0.00001626319,0.0000079680985,0.000046492045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995523,0.000042127198,0.00012739882,0.000098642086,0.00007825638,0.000101258905],"domain_scores_gemma":[0.9996676,0.000007891836,0.00010754618,0.00013579178,0.000050635772,0.00003052085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011142802,0.00006920459,0.00009188016,0.000015653775,0.000048352613,0.0000042745933,0.00006912498,0.000057438345,0.000062592095],"category_scores_gemma":[0.0000048427805,0.000046077566,0.000037276615,0.000033144795,0.000040165396,0.0000043722675,0.00005784112,0.000016742595,2.158524e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023877252,0.000023988094,0.007989489,0.00003860012,0.000017804852,6.755682e-8,0.000095312316,0.000034077108,0.98990804,0.00007794094,0.00009504648,0.001695737],"study_design_scores_gemma":[0.00013193721,0.00006581545,0.0029014768,0.00005515057,0.000017948536,0.000001684839,0.00012718816,0.0000073574197,0.9950358,0.000033655124,0.0015612919,0.00006064573],"about_ca_topic_score_codex":0.00064084394,"about_ca_topic_score_gemma":0.00007973738,"teacher_disagreement_score":0.009687581,"about_ca_system_score_codex":0.0000035216653,"about_ca_system_score_gemma":0.000022227157,"threshold_uncertainty_score":0.18789887},"labels":[],"label_agreement":null},{"id":"W2108878645","doi":"10.1096/fj.12-213314","title":"Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Strategiske Forskningsråd; Wellcome Trust; Wellcome","keywords":"Chemistry; Selectivity; Variation (astronomy); Ligand (biochemistry); Fatty acid; Receptor; Biochemistry; Combinatorial chemistry; Stereochemistry","score_opus":0.015760707194586002,"score_gpt":0.2332594981541663,"score_spread":0.2174987909595803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2108878645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9802559,0.00021859918,0.018225165,0.00060307037,0.0003792578,0.00011659578,0.00001959697,0.000012415444,0.00016937453],"genre_scores_gemma":[0.9965455,0.00005644156,0.00084311306,0.00030880436,0.0020609382,0.000008466017,0.000024218665,0.00001638701,0.00013612978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989777,0.00014941688,0.00018126401,0.00014459675,0.00021822879,0.00032877713],"domain_scores_gemma":[0.99941725,0.0000884267,0.00012190747,0.00020452256,0.000054110453,0.00011379726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010745854,0.00015438213,0.00012892569,0.000021479487,0.00034198345,0.000048062713,0.00031497848,0.00013263499,0.00033966],"category_scores_gemma":[0.00020092881,0.000084563646,0.00012596586,0.000074981144,0.0000449446,0.000008219474,0.0001107568,0.00037668855,0.000015540758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088123255,0.00003414507,0.0032907508,0.000002005001,0.0000574287,6.6592975e-7,0.00006831171,0.0005213067,0.9944683,0.0000168606,0.0011828806,0.00026925263],"study_design_scores_gemma":[0.00040895227,0.00015233936,0.008305477,0.0000071783425,0.000048995753,0.000024973655,0.000015157447,0.00018787486,0.9882133,0.000019913901,0.0024940337,0.00012180404],"about_ca_topic_score_codex":0.0000010451581,"about_ca_topic_score_gemma":5.729329e-7,"teacher_disagreement_score":0.017382054,"about_ca_system_score_codex":0.000056512854,"about_ca_system_score_gemma":0.00003241341,"threshold_uncertainty_score":0.3719039},"labels":[],"label_agreement":null},{"id":"W2109912409","doi":"10.1073/pnas.042705099","title":"Ligand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells","year":2002,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"National Institute of Neurological Disorders and Stroke; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Somatostatin receptor; Receptor; Ligand (biochemistry); Somatostatin; Chemistry; Somatostatin receptor 1; Somatostatin receptor 3; Förster resonance energy transfer; G protein-coupled receptor; Biophysics; Oligomer; Somatostatin receptor 2; Biology; Biochemistry; Fluorescence; Neuroscience","score_opus":0.03708906273871572,"score_gpt":0.26691287304497713,"score_spread":0.22982381030626142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109912409","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998056,0.00016155883,0.000004579748,0.00053268514,0.000051157956,0.00016629012,0.00000788513,0.0000033596473,0.0010165056],"genre_scores_gemma":[0.9969084,0.00022843,0.0024722628,0.00012468165,0.00007850444,0.000010742396,4.974946e-7,0.00000503119,0.00017144102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988095,0.000008037892,0.00030988414,0.00021886043,0.0004990184,0.00015470844],"domain_scores_gemma":[0.99954987,0.000021942327,0.00025402216,0.00000831284,0.00013008913,0.00003574138],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006507638,0.00009007125,0.00011072813,0.00017335145,0.000111788424,0.000026983216,0.00041166588,0.00010141575,0.00006307937],"category_scores_gemma":[0.00012628149,0.000067505935,0.00004973982,0.00051984284,0.00012569981,0.000047042093,0.00009515813,0.000089261746,0.000009976464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000071210575,0.000021535949,0.00029169378,0.000015415726,0.0000036344418,1.8089622e-9,0.0005747707,0.0000898125,0.995174,0.00080084795,0.00246524,0.0005559405],"study_design_scores_gemma":[0.00011072805,0.0000715474,0.000271048,0.00007868021,0.0000014665837,0.0000017627242,0.00062659767,0.00010174073,0.9966249,0.00064865896,0.0013776427,0.000085220556],"about_ca_topic_score_codex":0.0000023562761,"about_ca_topic_score_gemma":9.2758384e-8,"teacher_disagreement_score":0.0024676833,"about_ca_system_score_codex":0.00002230115,"about_ca_system_score_gemma":0.000006572713,"threshold_uncertainty_score":0.27528122},"labels":[],"label_agreement":null},{"id":"W2110093932","doi":"10.1016/j.parkreldis.2004.02.014","title":"Adenosine A2A-dopamine D2 receptor–receptor heteromers. Targets for neuro-psychiatric disorders","year":2004,"lang":"en","type":"review","venue":"Parkinsonism & Related Disorders","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":141,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Adenosine A2A receptor; Dopamine receptor D2; Neuroscience; Dopamine; G protein-coupled receptor; Receptor; Dopamine receptor D3; Dopamine receptor; Biology; Adenosine receptor; Biochemistry; Agonist","score_opus":0.00969640652882976,"score_gpt":0.2604189090264276,"score_spread":0.25072250249759787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110093932","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015109895,0.9879875,0.0034506286,0.00025148122,0.00393315,0.0031188773,0.00037517684,0.00015879486,0.0005732508],"genre_scores_gemma":[0.0004744436,0.9877441,0.0025890118,0.00013574249,0.00054649,0.0008845803,0.005843413,0.00056608254,0.0012161563],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9939501,0.00034023586,0.0016416837,0.0021648577,0.0004881291,0.0014149661],"domain_scores_gemma":[0.99716216,0.00013277815,0.0010776491,0.001085125,0.00011411209,0.00042818388],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.00048141147,0.0016252497,0.0020436875,0.0004738064,0.0005444623,0.00014185754,0.001098694,0.0018113534,0.00055222877],"category_scores_gemma":[0.00024655528,0.0015537058,0.002169035,0.00076060026,0.00021733747,0.00002304031,0.00025525896,0.00093186443,0.00026407122],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013215245,0.0005398181,0.0000061320393,0.005558727,0.0011591081,0.0000019672043,0.00008206097,0.00023451238,0.000959973,0.00019643526,0.007952221,0.9831769],"study_design_scores_gemma":[0.0020668814,0.0010352695,6.09633e-7,0.0012396589,0.00080095785,0.000016023878,0.0000464889,0.000022197006,0.00022597115,0.0005108784,0.99231064,0.0017243947],"about_ca_topic_score_codex":0.000053313684,"about_ca_topic_score_gemma":0.000033111002,"teacher_disagreement_score":0.98435843,"about_ca_system_score_codex":0.00015632661,"about_ca_system_score_gemma":0.0005352544,"threshold_uncertainty_score":0.9996495},"labels":[],"label_agreement":null},{"id":"W2110783096","doi":"10.1093/bioinformatics/btq264","title":"GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base","year":2010,"lang":"en","type":"article","venue":"Bioinformatics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Institutes of Health; Norwegian Biodiversity Information Centre","keywords":"Oligomer; G protein-coupled receptor; Base (topology); Receptor; Computer science; Computational biology; Chemistry; Biology; Biochemistry; Mathematics; Polymer chemistry","score_opus":0.009851811084422688,"score_gpt":0.23317525974567035,"score_spread":0.22332344866124768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110783096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.980312,0.0002075492,0.011832143,0.00026362317,0.001024304,0.00068118476,0.000027551085,0.000045720404,0.0056059435],"genre_scores_gemma":[0.9667006,0.000060009545,0.027539833,0.00048803067,0.0008644742,0.00010696374,0.00016566766,0.000045032968,0.0040293857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905795,0.00002468814,0.00031645893,0.0001415063,0.00014637595,0.00031302983],"domain_scores_gemma":[0.99913055,0.000014150787,0.0001234543,0.00049654517,0.00011877322,0.00011655917],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004680068,0.00017853222,0.00012815122,0.000033196426,0.0001912156,0.00007151592,0.00033728385,0.00020058232,0.00046079556],"category_scores_gemma":[0.0001423094,0.000118651464,0.00010734956,0.000103553786,0.000084522886,0.0000093817325,0.00012642764,0.00022006953,0.00031324523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017953016,0.000034980836,0.000022511678,0.00003033476,0.000023764116,2.1081503e-7,0.00024108904,0.000003820857,0.9918613,0.0009912571,0.0038726395,0.0029001497],"study_design_scores_gemma":[0.00042770285,0.00014595619,0.000025147061,0.000017689561,0.000013682467,0.000009893862,0.00031765274,0.00899888,0.71156347,0.00007799841,0.27813065,0.00027124965],"about_ca_topic_score_codex":0.0000071279965,"about_ca_topic_score_gemma":0.000025034204,"teacher_disagreement_score":0.28029782,"about_ca_system_score_codex":0.000007971031,"about_ca_system_score_gemma":0.000116162155,"threshold_uncertainty_score":0.50453883},"labels":[],"label_agreement":null},{"id":"W2111689719","doi":"10.1038/emboj.2012.26","title":"A novel evolutionarily conserved domain of cell‐adhesion GPCRs mediates autoproteolysis","year":2012,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":469,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biological and Environmental Research; Basic Energy Sciences; National Center for Research Resources; National Institute of General Medical Sciences; National Institute of Mental Health; Canadian Institutes of Health Research; National Institutes of Health; Life Sciences Research Foundation; U.S. Department of Energy; Howard Hughes Medical Institute","keywords":"Biology; G protein-coupled receptor; Cell adhesion; Cell biology; Domain (mathematical analysis); Computational biology; Cell; Evolutionary biology; Genetics; Signal transduction","score_opus":0.013173888038297233,"score_gpt":0.22798853296653085,"score_spread":0.21481464492823363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111689719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9816419,0.002034602,0.015402396,0.00018954603,0.00031668364,0.00007953118,0.0000064113615,0.000003759116,0.0003251709],"genre_scores_gemma":[0.9915873,0.00014858603,0.007299606,0.00009458935,0.00063640764,0.0000045706183,0.000007773945,0.000013182259,0.00020800564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913424,0.000097157135,0.00024578883,0.00008837213,0.00019515285,0.00023928018],"domain_scores_gemma":[0.99941343,0.000023570688,0.00020493222,0.0001680588,0.0000886683,0.0001013295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008347426,0.00010271571,0.0001281574,0.000032220054,0.00017490912,0.00001620518,0.0002082294,0.000079529396,0.00022697041],"category_scores_gemma":[0.0000509187,0.000066389104,0.00014533002,0.00006361968,0.000059811406,0.0000065131712,0.0000653964,0.00014006991,0.0000077754385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004709,0.00006519064,0.0006071823,0.000005798137,0.00004207164,4.3005525e-7,0.00019738305,0.000040349263,0.99808586,0.00017933342,0.00055904605,0.00017025313],"study_design_scores_gemma":[0.00046391375,0.00011460021,0.0011486136,0.000015234668,0.00003296281,0.00012859315,0.00037697973,0.00005267239,0.9943929,0.0006594444,0.0025133374,0.00010076873],"about_ca_topic_score_codex":0.000013801512,"about_ca_topic_score_gemma":0.0000017248549,"teacher_disagreement_score":0.009945379,"about_ca_system_score_codex":0.000013250091,"about_ca_system_score_gemma":0.000055093635,"threshold_uncertainty_score":0.2707269},"labels":[],"label_agreement":null},{"id":"W2111960652","doi":"10.1016/j.bmc.2010.08.005","title":"Novel imidazoline compounds as partial or full agonists of D2-like dopamine receptors inspired by I2-imidazoline binding sites ligand 2-BFI","year":2010,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Imidazoline receptor; Chemistry; Dopamine; Ligand (biochemistry); Stereochemistry; Dopamine receptor D2; Partial agonist; Receptor; Agonist; Pharmacology; Biochemistry; Internal medicine","score_opus":0.0118793264300184,"score_gpt":0.24942220841030563,"score_spread":0.23754288198028722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111960652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969312,0.00066748634,0.00065314333,0.0002599202,0.00084840396,0.00019498772,0.00012971024,0.00005036616,0.0002647854],"genre_scores_gemma":[0.99390584,0.00024949713,0.0010970432,0.0001816579,0.001742609,0.000016711,0.0013082507,0.000088382636,0.0014099812],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99729335,0.000024208126,0.0007937166,0.0007735733,0.00051584566,0.0005993329],"domain_scores_gemma":[0.9982523,0.000050861807,0.0004402622,0.0006251363,0.00022356382,0.000407931],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00046153073,0.00050855946,0.00059132907,0.00005392087,0.00017555435,0.00004300197,0.0005717266,0.00063041586,0.0013762626],"category_scores_gemma":[0.00042269242,0.0004316669,0.00017588382,0.00029287566,0.00032499258,0.00001227954,0.0002205377,0.00050067704,0.000019505986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005419215,0.0002790956,0.0003812432,0.00014466347,0.0001212832,0.000011109114,0.000063349864,0.0000015262304,0.9948201,0.000007683854,0.0031537497,0.0004742789],"study_design_scores_gemma":[0.001872986,0.00043135483,0.00003238238,0.00008346437,0.00009580558,0.00027017936,0.00021059718,0.00007301053,0.9718213,0.0000072007165,0.02461724,0.00048447732],"about_ca_topic_score_codex":0.0000737335,"about_ca_topic_score_gemma":0.00004224572,"teacher_disagreement_score":0.022998793,"about_ca_system_score_codex":0.000038019618,"about_ca_system_score_gemma":0.0003256618,"threshold_uncertainty_score":0.9998135},"labels":[],"label_agreement":null},{"id":"W2112482916","doi":"10.1124/mol.113.089649","title":"Identification of Novel Functionally Selective κ-Opioid Receptor Scaffolds","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":139,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; National Institute of General Medical Sciences; National Institute on Drug Abuse; Wellcome Trust","keywords":"Arrestin; Functional selectivity; Pharmacology; Dynorphin; G protein-coupled receptor; Dysphoria; Neuroscience; Opioid; Chemistry; Receptor; Medicine; Biology; Opioid peptide; Biochemistry","score_opus":0.00716458064414528,"score_gpt":0.2511987866810394,"score_spread":0.24403420603689413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112482916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93203384,0.00031954327,0.06606002,0.00016900449,0.0006556857,0.0003871529,0.000015960246,0.000015924246,0.00034287153],"genre_scores_gemma":[0.9966106,0.00004817857,0.001707689,0.0005746393,0.00020134012,0.00015298219,0.000109923065,0.00002940146,0.0005652478],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884194,0.000078404046,0.00033104836,0.00036227316,0.00014963362,0.0002367282],"domain_scores_gemma":[0.99921846,0.000011431737,0.00017986454,0.00017538444,0.00033547592,0.000079367586],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018174271,0.00015379976,0.0001614945,0.00007691337,0.000060762974,0.000014964408,0.00019534283,0.00017383171,0.001182897],"category_scores_gemma":[0.000026571577,0.00016022743,0.00011928966,0.00014119357,0.000069582755,0.000007810563,0.00007658522,0.000065431894,0.00006629568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043099983,0.00015241014,0.000053063588,0.000013954782,0.00014032036,6.1244504e-7,0.00003058885,0.00036898736,0.99174327,0.00027852083,0.0063638575,0.00081130833],"study_design_scores_gemma":[0.00071568997,0.00021844618,0.00021748795,0.000003172473,0.000037051206,0.000007578427,0.00003493727,0.0005934703,0.9930725,0.00013516043,0.0048041767,0.00016032449],"about_ca_topic_score_codex":0.000018891687,"about_ca_topic_score_gemma":8.5649583e-7,"teacher_disagreement_score":0.06457676,"about_ca_system_score_codex":0.000021380176,"about_ca_system_score_gemma":0.00008316645,"threshold_uncertainty_score":0.99973017},"labels":[],"label_agreement":null},{"id":"W2112800522","doi":"10.1186/1750-2187-6-9","title":"Heterodimerization of β&lt;sub&gt;2&lt;/sub&gt; adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway","year":2011,"lang":"en","type":"article","venue":"Journal of Molecular Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"Michael Smith Health Research BC","keywords":"NFAT; Adenylyl cyclase; Somatostatin receptor; Cell biology; Receptor; Signal transduction; Biology; Enzyme-linked receptor; Dephosphorylation; Chemistry; Phosphorylation; Biochemistry; Transcription factor; Phosphatase","score_opus":0.013092499669763351,"score_gpt":0.21731315362629447,"score_spread":0.2042206539565311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112800522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9208639,0.0015125092,0.07717294,0.00002476162,0.00015045234,0.00020070643,0.000022739789,0.0000058081177,0.000046155452],"genre_scores_gemma":[0.9814509,0.00031209723,0.017967073,0.00004054526,0.00009720188,0.000008977527,0.000067243775,0.000050816117,0.000005137034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99754065,0.00025659797,0.0012621316,0.00032694952,0.0003452255,0.0002684508],"domain_scores_gemma":[0.9977656,0.000038865444,0.0012807918,0.0002589048,0.0005212159,0.00013461271],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008673572,0.0002570431,0.00047719912,0.0003078656,0.00006533253,0.000021251173,0.00024337592,0.000245591,0.00005561202],"category_scores_gemma":[0.00017179066,0.0002567629,0.00022779584,0.00030366218,0.00007675247,0.000036870526,0.00007349296,0.00017032724,9.491556e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018661542,0.00013273592,0.00074193144,0.000066595734,0.00010487618,0.0000036816896,0.00046067405,0.0060755354,0.9883703,0.00053583074,0.000011631281,0.0033095758],"study_design_scores_gemma":[0.0008520047,0.00057870056,0.000505415,0.00026404802,0.00004707737,0.000023979375,0.00012971593,0.00040605591,0.9963816,0.00048211298,0.00008614573,0.00024313602],"about_ca_topic_score_codex":0.000008550228,"about_ca_topic_score_gemma":0.000003552889,"teacher_disagreement_score":0.06058698,"about_ca_system_score_codex":0.000029599196,"about_ca_system_score_gemma":0.0001608513,"threshold_uncertainty_score":0.99998844},"labels":[],"label_agreement":null},{"id":"W2112827150","doi":"10.1093/emboj/cdg383","title":"Phosphorylation‐independent desensitization of GABAB receptor by GRK4","year":2003,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"Canada Research Chairs; GlaxoSmithKline","keywords":"Homologous desensitization; Desensitization (medicine); GABAB receptor; Agonist; Biology; Receptor; G protein-coupled receptor; G protein-coupled receptor kinase; Cell biology; HEK 293 cells; Metabotropic receptor; Signal transduction; Pharmacology; Biochemistry","score_opus":0.006868949462600933,"score_gpt":0.2171506747505618,"score_spread":0.21028172528796085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112827150","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96291983,0.0009761667,0.03419584,0.000080526566,0.0003805622,0.00007001138,0.0000049672117,0.0000029658668,0.0013691583],"genre_scores_gemma":[0.9976663,0.00032334455,0.000953316,0.00009046819,0.00015005958,0.0000013377564,0.000016619,0.000013260796,0.0007853214],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928766,0.00012493238,0.00019839121,0.00009434147,0.00016670581,0.00012798813],"domain_scores_gemma":[0.9995419,0.000010521452,0.0001506683,0.00012674325,0.000119008786,0.000051184674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053535774,0.00007744301,0.00008243561,0.000017197208,0.00013726851,0.00002466462,0.00010594865,0.00005785274,0.00044745472],"category_scores_gemma":[0.000084310785,0.00005479163,0.00007088191,0.0000527429,0.000028240582,0.0000038215944,0.000014888524,0.00010515601,0.000008500973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024017549,0.000020516703,0.00015871288,0.000001897929,0.00003155968,4.9477944e-7,0.00006110316,0.0003950481,0.9924007,0.0005502641,0.0054012276,0.0009544374],"study_design_scores_gemma":[0.00026629376,0.00009473687,0.000041944237,0.000008585848,0.000011849876,0.000065266955,0.00017099983,0.00005309382,0.9795802,0.0006525078,0.018980153,0.0000743185],"about_ca_topic_score_codex":0.000003700758,"about_ca_topic_score_gemma":0.0000011888078,"teacher_disagreement_score":0.03474647,"about_ca_system_score_codex":0.000012901496,"about_ca_system_score_gemma":0.000051110037,"threshold_uncertainty_score":0.48993155},"labels":[],"label_agreement":null},{"id":"W2112944102","doi":"10.1073/pnas.1018280108","title":"Quantification of receptor tyrosine kinase transactivation through direct dimerization and surface density measurements in single cells","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":90,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Transactivation; G protein-coupled receptor; Cell biology; Tropomyosin receptor kinase B; Receptor tyrosine kinase; Receptor; Biology; Internalization; Signal transduction; Chemistry; Biochemistry; Transcription factor; Gene","score_opus":0.0866895963177143,"score_gpt":0.27694543751984535,"score_spread":0.19025584120213107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112944102","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991068,0.00009264627,0.00015553791,0.00006174008,0.000016825554,0.000110345245,0.0000048077113,0.0000015112964,0.0004497489],"genre_scores_gemma":[0.99581355,0.00005206062,0.0040887203,0.000017959324,0.000009953241,0.0000015752845,6.9725036e-7,0.0000025871966,0.000012902975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992624,0.0000098083765,0.0002036549,0.0001566303,0.00030890087,0.000058626],"domain_scores_gemma":[0.99952835,0.000009232628,0.00026384872,0.0000069611096,0.00018172304,0.000009909878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063954794,0.000052008494,0.000082331695,0.000033323773,0.00004758688,0.0000046268765,0.00013782487,0.00006294149,0.000005975502],"category_scores_gemma":[0.00010388908,0.00004025375,0.000023994293,0.00023016203,0.00016913484,0.000034446028,0.000019630863,0.000031868236,6.823712e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030784675,0.000056912202,0.0051238267,0.000025963536,0.0000051306897,2.0715066e-10,0.0002198784,0.00012263178,0.99368954,0.00059393427,0.000009771401,0.000121632016],"study_design_scores_gemma":[0.000104785955,0.00006474341,0.009952095,0.000042808253,0.000004695339,1.9210128e-7,0.000079682366,0.00012383547,0.988528,0.0010466466,0.000010768844,0.000041725216],"about_ca_topic_score_codex":0.000019791561,"about_ca_topic_score_gemma":2.4685684e-7,"teacher_disagreement_score":0.0051615136,"about_ca_system_score_codex":0.000008119648,"about_ca_system_score_gemma":0.000011520825,"threshold_uncertainty_score":0.16415004},"labels":[],"label_agreement":null},{"id":"W2113881557","doi":"10.1530/rep.0.1210485","title":"Inhibition of basal and stimulated progesterone synthesis by dichlorodiphenyldichloroethylene and methoxychlor in a stable pig granulosa cell line","year":2001,"lang":"en","type":"article","venue":"Reproduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; Medical Research Council Canada","keywords":"Methoxychlor; Cholera toxin; Internal medicine; Endocrinology; Chemistry; Cholesterol side-chain cleavage enzyme; Incubation; Biology; Biochemistry; Cytochrome P450; Metabolism; Medicine","score_opus":0.00951865515018328,"score_gpt":0.22864818791815955,"score_spread":0.21912953276797628,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2113881557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99316037,0.0030146334,0.0032919568,0.0001593364,0.00006851943,0.00024112905,0.000010815181,0.000010338593,0.00004289945],"genre_scores_gemma":[0.9964833,0.001829615,0.0012761758,0.000017134376,0.00010958747,0.000025441252,0.00006002917,0.000018664558,0.00018005389],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889064,0.000081425955,0.00025686176,0.0005114407,0.000101886886,0.00015773822],"domain_scores_gemma":[0.9995428,0.000013330334,0.00010717132,0.00022157781,0.00006641501,0.000048705577],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056933647,0.0001277574,0.00018478505,0.000065827255,0.000043293385,0.00001425604,0.000028670227,0.00012364722,0.000020642043],"category_scores_gemma":[0.00011618052,0.00012519034,0.0000236441,0.00012862263,0.00004975895,0.000014525968,0.000040807685,0.00007158697,4.7013936e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023259307,0.00011019673,0.0014194075,0.000058396658,0.00001211397,0.0000013943518,0.00006955259,0.00012813414,0.9905801,0.000003862352,0.000049521856,0.0073347325],"study_design_scores_gemma":[0.00049663166,0.00028055187,0.00047540604,0.000037725775,0.000023379476,0.000014123001,0.00009012047,0.00027738622,0.9972475,0.00014039378,0.0007875998,0.00012918342],"about_ca_topic_score_codex":0.000106272055,"about_ca_topic_score_gemma":0.000014016179,"teacher_disagreement_score":0.007205549,"about_ca_system_score_codex":0.000010939344,"about_ca_system_score_gemma":0.000014529829,"threshold_uncertainty_score":0.51051146},"labels":[],"label_agreement":null},{"id":"W2114208463","doi":"10.1016/j.neuropharm.2005.11.010","title":"Expression of D2 receptor isoforms in cultured neurons reveals equipotent autoreceptor function","year":2006,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Université de Montréal","funders":"","keywords":"Autoreceptor; Dopamine receptor D2; Neurotransmitter; Cell biology; Receptor; Biology; Gene isoform; Dopamine; Neuroscience; Subcellular localization; Alternative splicing; Neurotransmitter receptor; Biochemistry; Agonist; Gene; Cytoplasm","score_opus":0.008422766295817015,"score_gpt":0.24395267704608578,"score_spread":0.23552991075026877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114208463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963143,0.0003283968,0.0010888407,0.00010254191,0.0013865072,0.00030100442,0.00001848257,0.000024069443,0.0004358515],"genre_scores_gemma":[0.9971403,0.00014416662,0.0007020888,0.00037494896,0.00048485707,0.000046007106,0.000106683154,0.000035559326,0.00096538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984351,0.00019667772,0.0004408749,0.00044015926,0.00014774984,0.00033948035],"domain_scores_gemma":[0.99944,0.000022738255,0.00019188806,0.00019711083,0.00008099582,0.0000672269],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017015281,0.00019900438,0.00024503085,0.000095561954,0.00006157436,0.000009617695,0.00019125307,0.00021071504,0.00061537576],"category_scores_gemma":[0.000045686575,0.00017523933,0.000116374606,0.0001510211,0.00005923152,0.000008603156,0.00011387395,0.00017348344,0.000021040702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034685695,0.000153541,0.00083657773,0.000020354762,0.000007718588,0.0000046965984,0.000015916336,0.0006632713,0.986522,0.00008635234,0.010671138,0.000671552],"study_design_scores_gemma":[0.0010591317,0.0006439104,0.002304154,0.000012444765,0.000016694717,0.0000060362127,0.000017141978,0.000069625254,0.96334976,0.000097103395,0.03225738,0.00016659747],"about_ca_topic_score_codex":0.00002410996,"about_ca_topic_score_gemma":0.000005546615,"teacher_disagreement_score":0.023172246,"about_ca_system_score_codex":0.000020311643,"about_ca_system_score_gemma":0.000038524482,"threshold_uncertainty_score":0.7146053},"labels":[],"label_agreement":null},{"id":"W2114360276","doi":"10.1523/jneurosci.23-19-07415.2003","title":"Freud-1: A Neuronal Calcium-Regulated Repressor of the 5-HT1A Receptor Gene","year":2003,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Repressor; Biology; 5-HT1A receptor; Psychological repression; Cell biology; Molecular biology; Receptor; Gene; Genetics; Transcription factor; 5-HT receptor; Gene expression; Serotonin","score_opus":0.02125201959249982,"score_gpt":0.25455334796647566,"score_spread":0.23330132837397585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114360276","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958373,0.00018013954,0.0024528664,0.00013723913,0.0012006545,0.000064816835,0.0000050837157,0.0000017076006,0.0001202117],"genre_scores_gemma":[0.9981333,0.00007615688,0.0009045877,0.0003857912,0.00009924504,7.621871e-7,3.1004188e-7,0.000010591947,0.0003892518],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872005,0.00016030914,0.00036617013,0.00024006155,0.00033871765,0.00017466601],"domain_scores_gemma":[0.99895287,0.000014020384,0.0004167596,0.0003636974,0.00016914819,0.000083528714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005419921,0.00009878495,0.00014547342,0.000037273407,0.00009080945,0.000021001792,0.0004591991,0.000061908395,0.0000348258],"category_scores_gemma":[0.00060658326,0.000064827975,0.00016895683,0.00020403422,0.00013101178,0.0000089746045,0.000055231612,0.00014057379,6.489064e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024753159,0.00004254724,0.00046872834,0.000002967035,0.0000037760396,0.0000023197538,0.000020921749,0.00054447044,0.99822426,0.0000812204,0.00047313247,0.000110928864],"study_design_scores_gemma":[0.00023681298,0.00032438603,0.0034093417,0.000013646371,0.00000930116,0.0001499335,0.000011053499,0.000060233513,0.98150194,0.00007353128,0.014141721,0.000068087036],"about_ca_topic_score_codex":0.0000015959442,"about_ca_topic_score_gemma":3.316957e-7,"teacher_disagreement_score":0.016722282,"about_ca_system_score_codex":0.000007134361,"about_ca_system_score_gemma":0.00013267143,"threshold_uncertainty_score":0.26436082},"labels":[],"label_agreement":null},{"id":"W2114415045","doi":"10.1152/ajpheart.00798.2003","title":"Alterations of adenylyl cyclase and G proteins in aortocaval shunt-induced heart failure","year":2004,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Merck Canada","keywords":"Adenylyl cyclase; Internal medicine; Heart failure; Endocrinology; Forskolin; G protein; Alpha (finance); Chemistry; Losartan; Medicine; Stimulation; Angiotensin II; Receptor; Surgery","score_opus":0.008020546430381985,"score_gpt":0.23848109729098174,"score_spread":0.23046055086059974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114415045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991042,0.00035015325,0.000029743966,0.0002474942,0.000100089885,0.0001539548,0.000005758607,0.0000035759278,0.000005047113],"genre_scores_gemma":[0.9980058,0.00005692878,0.0012922665,0.00035421696,0.00025014303,0.000009692504,0.0000102049025,0.000018537301,0.0000021860328],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866885,0.00016794917,0.0004572346,0.00033987756,0.00009581756,0.00027024822],"domain_scores_gemma":[0.9992166,0.00002345741,0.00030873984,0.00021109966,0.0001114353,0.00012863899],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020762667,0.00019527347,0.0005697064,0.0001245759,0.000075997414,0.0000076360875,0.00011405459,0.00013528221,0.000018442934],"category_scores_gemma":[0.000037018068,0.0001734597,0.00013338686,0.0001235773,0.00039267432,0.000018292214,0.00006318061,0.00025269712,0.0000011756995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000116970536,0.00009743335,0.00082197133,0.00001985715,0.000060975115,3.7326686e-7,0.00014034419,0.00034970097,0.99805987,0.0001762011,0.000029251041,0.00012705453],"study_design_scores_gemma":[0.0016408192,0.003626238,0.2954307,0.00007873937,0.000037062095,0.00020434862,0.0007696964,0.00002650857,0.69515127,0.0021467605,0.0005788882,0.00030896915],"about_ca_topic_score_codex":0.000052524636,"about_ca_topic_score_gemma":0.000021172014,"teacher_disagreement_score":0.3029086,"about_ca_system_score_codex":0.000016041055,"about_ca_system_score_gemma":0.00016809742,"threshold_uncertainty_score":0.70734817},"labels":[],"label_agreement":null},{"id":"W2114784474","doi":"10.1124/jpet.105.091256","title":"Modulation of Agonist Binding to Human Dopamine Receptor Subtypes by l-Prolyl-l-leucyl-glycinamide and a Peptidomimetic Analog","year":2005,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McMaster University","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Agonist; Receptor; Partial agonist; Chemistry; Endogenous agonist; Radioligand; Inverse agonist; Pharmacology; Biochemistry; Biology; Dopamine receptor D1","score_opus":0.014591356861581075,"score_gpt":0.31221785720880263,"score_spread":0.29762650034722155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2114784474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99443054,0.0045053125,0.0004708399,0.00026494008,0.00017317793,0.00010672773,0.000007924548,0.000002460888,0.000038096685],"genre_scores_gemma":[0.9967904,0.0004805437,0.0018137748,0.00048426984,0.00027242186,0.0000034164532,0.000011014959,0.000015080019,0.00012909074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992145,0.000067461886,0.00032878862,0.00014608586,0.0000956727,0.00014752588],"domain_scores_gemma":[0.99956936,0.000013870544,0.00022238615,0.00005106231,0.000060650305,0.00008268186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023496199,0.0001308672,0.00021204725,0.00008006081,0.00010465232,0.00001515791,0.00008949624,0.00009818944,0.0000984213],"category_scores_gemma":[0.000003215287,0.00011614028,0.00005550368,0.000054601238,0.00008064979,0.000013143228,0.000048641574,0.0000991205,0.000001001902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004216673,0.00013361654,0.00036067504,0.000007637217,0.00014402751,0.0000010224605,0.00024393406,0.000075285105,0.9960375,0.000023867819,0.00055708317,0.0019937155],"study_design_scores_gemma":[0.0012924611,0.001440025,0.00009177001,0.000009918422,0.000055735956,0.000039333772,0.00025989785,0.00016844651,0.9886004,0.000014906823,0.0079085305,0.00011858164],"about_ca_topic_score_codex":0.0000029347214,"about_ca_topic_score_gemma":8.201008e-7,"teacher_disagreement_score":0.0074370755,"about_ca_system_score_codex":0.000028034694,"about_ca_system_score_gemma":0.000022456168,"threshold_uncertainty_score":0.47360635},"labels":[],"label_agreement":null},{"id":"W2115036443","doi":"10.1073/pnas.0305322101","title":"Heterodimerization of V1a and V2 vasopressin receptors determines the interaction with β-arrestin and their trafficking patterns","year":2004,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Kidney Foundation of Canada; Sanofi","keywords":"Internalization; Receptor; Endosome; G protein-coupled receptor; Arrestin; Agonist; Cell biology; Arginine vasopressin receptor 2; Vasopressin receptor; Biology; Intracellular; Chemistry; Biochemistry; Antagonist","score_opus":0.021509366665185617,"score_gpt":0.2642042213472632,"score_spread":0.24269485468207758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115036443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9993005,0.00011968368,0.00009684706,0.00033133058,0.00001523596,0.000078369805,0.000003113987,0.0000016713462,0.00005326958],"genre_scores_gemma":[0.9992279,0.000071179114,0.0006091457,0.000046114532,0.000033922344,0.0000032732214,3.197499e-7,0.000002826332,0.000005356082],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994859,0.0000052607884,0.00013587589,0.00013322145,0.00018356826,0.0000561419],"domain_scores_gemma":[0.9996387,0.00001967752,0.00023568078,0.0000061315195,0.00008786151,0.000011975009],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032010485,0.00005976682,0.00006837397,0.000033494223,0.00009808857,0.000016309414,0.00015123462,0.00004130534,0.0000015655208],"category_scores_gemma":[0.00007235262,0.000029852963,0.000019767629,0.00010032115,0.00027901246,0.000025079049,0.00005061165,0.000046662462,1.15295915e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001625896,0.000009077713,0.004079296,0.000023362358,0.000008522159,7.384615e-10,0.00026610526,0.00040631124,0.9933503,0.00040885672,0.0000033758654,0.0014284921],"study_design_scores_gemma":[0.00011991189,0.00010073445,0.005918985,0.00011502305,0.0000055992546,0.000008922686,0.00055727066,0.00031768857,0.99178004,0.0010088788,0.000026800568,0.000040114606],"about_ca_topic_score_codex":0.000005581419,"about_ca_topic_score_gemma":3.059645e-7,"teacher_disagreement_score":0.0018396898,"about_ca_system_score_codex":0.0000033270148,"about_ca_system_score_gemma":0.000010296078,"threshold_uncertainty_score":0.12173685},"labels":[],"label_agreement":null},{"id":"W2115142635","doi":"10.1111/ejn.12279","title":"Cholinergic control of morphine‐induced locomotion in rostromedial tegmental nucleus versus ventral tegmental area sites","year":2013,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Ventral tegmental area; Nucleus accumbens; Neuroscience; Dopamine; Tyrosine hydroxylase; Biology; Internal medicine; Chemistry; Endocrinology; Dopaminergic; Medicine","score_opus":0.02264943635098771,"score_gpt":0.23519586168575018,"score_spread":0.21254642533476248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115142635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978293,0.00004898439,0.0010438901,0.000077224075,0.0007674048,0.00010717633,0.0000075189596,0.0000026411474,0.000115829534],"genre_scores_gemma":[0.9992681,0.00003275754,0.00031393347,0.0001294691,0.0002189668,8.4326734e-7,0.0000040421696,0.000015479876,0.000016420063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987592,0.00016651303,0.00041703868,0.00018737916,0.00025161117,0.00021823519],"domain_scores_gemma":[0.9993122,0.0000118479575,0.0003144741,0.00011878899,0.0000703977,0.0001722435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000366288,0.00012267353,0.00015851433,0.00008457661,0.00004237447,0.000040387247,0.00032915064,0.000024289402,0.00007207818],"category_scores_gemma":[0.00018842299,0.00010415029,0.00010509127,0.00011389349,0.00008253142,0.00003012472,0.00006240577,0.00014900816,0.0000046151595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001359,0.00010951134,0.0007451331,0.0000026496202,0.000003936928,0.000040884574,0.00003403835,0.00076868123,0.99741334,0.0000039654697,0.00006493899,0.00067700585],"study_design_scores_gemma":[0.0063578603,0.0059383227,0.07709133,0.000055042136,0.00001979442,0.00020114784,0.00019156007,0.002785081,0.9068064,0.000012595276,0.00028418645,0.0002566855],"about_ca_topic_score_codex":0.000003835535,"about_ca_topic_score_gemma":7.8799167e-7,"teacher_disagreement_score":0.09060696,"about_ca_system_score_codex":0.00001787528,"about_ca_system_score_gemma":0.000046628316,"threshold_uncertainty_score":0.42471257},"labels":[],"label_agreement":null},{"id":"W2115310323","doi":"10.1074/jbc.m201731200","title":"Effects of N-Ethylmaleimide on Conformational Equilibria in Purified Cardiac Muscarinic Receptors","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Quinuclidinyl Benzilate; Muscarinic acetylcholine receptor; Chemistry; N-Ethylmaleimide; Carbachol; Dithiothreitol; Agonist; Receptor; Muscarinic acetylcholine receptor M2; Endocrinology; Internal medicine; Biochemistry; Biology","score_opus":0.015959106801944623,"score_gpt":0.227912343017669,"score_spread":0.21195323621572437,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115310323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969442,0.0010740787,0.00005929501,0.000040368835,0.00024258862,0.000069289155,0.0000047186736,0.0000028508018,0.0015626111],"genre_scores_gemma":[0.99849135,0.00066081254,0.00030229756,0.000061655,0.00032266902,0.0000035724386,0.000013325752,0.000007328994,0.00013700326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989127,0.00006601583,0.0005170724,0.00014729433,0.00017684414,0.00018005352],"domain_scores_gemma":[0.99927104,0.00009495,0.00033950515,0.000115981,0.000088609966,0.00008990072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032284565,0.00013967515,0.00031447865,0.000032381642,0.000019073432,0.000008805921,0.00020908169,0.00029198398,0.00032464432],"category_scores_gemma":[0.00038093916,0.00010383628,0.00024369801,0.000074229036,0.00006938842,0.0000056247723,0.00004826483,0.00022702385,0.0000039005586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013376826,0.00010751643,0.0008392787,0.000046372148,0.00004243241,0.0000061682636,0.000023525055,0.000048809165,0.9969104,0.000020709367,0.00046272992,0.0013583191],"study_design_scores_gemma":[0.00064110936,0.00046612404,0.0008370306,0.00006399691,0.000009273649,0.000013796506,0.000046149657,0.000030452276,0.99485177,0.00008240676,0.0028388244,0.000119060125],"about_ca_topic_score_codex":7.489889e-7,"about_ca_topic_score_gemma":4.7354256e-8,"teacher_disagreement_score":0.0023760945,"about_ca_system_score_codex":0.000022384422,"about_ca_system_score_gemma":0.000025474299,"threshold_uncertainty_score":0.42343208},"labels":[],"label_agreement":null},{"id":"W2116106189","doi":"10.1038/sj.emboj.7601929","title":"Prolonged Gq activity triggers fly rhodopsin endocytosis and degradation, and reduces photoreceptor sensitivity","year":2007,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institutes of Health; Indigenous and Northern Affairs Canada","keywords":"Rhodopsin; Arrestin; Biology; Cell biology; Endocytosis; Endocytic cycle; Signal transduction; Visual phototransduction; Effector; Transduction (biophysics); G protein-coupled receptor; Receptor; Retina; Biochemistry; Retinal; Neuroscience","score_opus":0.011700068659614038,"score_gpt":0.24861391095017607,"score_spread":0.23691384229056203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2116106189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934662,0.00066079124,0.005062748,0.00032964634,0.00021439634,0.00012754249,0.0000043508903,0.0000066347775,0.00012767082],"genre_scores_gemma":[0.9976031,0.00045715418,0.0012411287,0.000120023076,0.00041913392,0.0000021187695,0.0000037206469,0.0000138142395,0.00013978126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990789,0.00019576131,0.00015859024,0.00019027785,0.00014316449,0.00023329213],"domain_scores_gemma":[0.9994928,0.000061776744,0.00013803417,0.00010987507,0.00007466067,0.0001228104],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017916791,0.00013254787,0.00013812003,0.000038056107,0.0003674646,0.00008938825,0.0000690172,0.00007857825,0.000030280213],"category_scores_gemma":[0.00011755446,0.00009130231,0.000054314416,0.00005699616,0.00009671486,0.000012579527,0.000049562736,0.0002049729,9.133372e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022178101,0.000019809786,0.0003076555,0.0000033933761,0.00004832872,0.0000064349956,0.00015144344,0.0000030857095,0.9620835,0.000010571071,0.00028323394,0.03686073],"study_design_scores_gemma":[0.00042417168,0.0001649307,0.0022418415,0.000011934117,0.0000290331,0.00057753525,0.00022652632,0.000063684056,0.9942424,0.00012557436,0.0017665133,0.00012581801],"about_ca_topic_score_codex":0.000014079846,"about_ca_topic_score_gemma":0.000019757641,"teacher_disagreement_score":0.036734913,"about_ca_system_score_codex":0.00001568542,"about_ca_system_score_gemma":0.000048306138,"threshold_uncertainty_score":0.37232003},"labels":[],"label_agreement":null},{"id":"W2116265895","doi":"10.1111/j.1476-5381.2011.01552.x","title":"Regulation of GPCR activity, trafficking and localization by GPCR‐interacting proteins","year":2011,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":353,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Cell biology; Biology; GTPase-activating protein; G protein; Rhodopsin-like receptors; GTPase; Signal transduction; Receptor; Biochemistry","score_opus":0.02509186853333753,"score_gpt":0.3139019394436485,"score_spread":0.28881007091031097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2116265895","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0068879975,0.9819707,0.010149705,0.000004956109,0.0005845903,0.00032796134,0.000023604085,0.0000034238371,0.000047008452],"genre_scores_gemma":[0.047812812,0.95112574,0.00041808953,0.000018570992,0.00047188002,0.000008826933,0.00004246845,0.000039989212,0.00006162244],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99848217,0.00033522438,0.0006707798,0.00022472083,0.00011175206,0.00017537578],"domain_scores_gemma":[0.9981881,0.000035615692,0.001459371,0.00005104169,0.00019617632,0.00006971087],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005034068,0.00019191639,0.0007534669,0.00009900483,0.00006965479,0.000028354301,0.00017301276,0.0003286714,0.00020073332],"category_scores_gemma":[0.000067238056,0.00020924534,0.0002436561,0.000077242425,0.00005708871,0.000016696064,0.00007537469,0.0003196052,5.1498205e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037268957,0.000079690835,0.0000010697471,0.0012541938,0.00022378955,0.000014310463,0.000022020728,0.000015292424,0.2547151,0.000003324783,0.002205062,0.74142885],"study_design_scores_gemma":[0.0007393023,0.00056390546,0.000002562437,0.004867694,0.0007311061,0.0032464303,0.000018089615,0.000078017685,0.17640103,0.000016973521,0.81302917,0.00030568754],"about_ca_topic_score_codex":0.000021461505,"about_ca_topic_score_gemma":0.000004565979,"teacher_disagreement_score":0.81082416,"about_ca_system_score_codex":0.000026529398,"about_ca_system_score_gemma":0.00013809101,"threshold_uncertainty_score":0.8532777},"labels":[],"label_agreement":null},{"id":"W2117294811","doi":"10.1074/jbc.m114.615658","title":"GRK2 Targeted Knock-down Results in Spontaneous Hypertension, and Altered Vascular GPCR Signaling","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Beta adrenergic receptor kinase; Signal transduction; Receptor; Medicine; Pharmacology; Biology; Neuroscience; Cell biology; Internal medicine","score_opus":0.02746717275136462,"score_gpt":0.23218664959973884,"score_spread":0.20471947684837422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117294811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996066,0.0032343408,0.00022688218,0.00008759298,0.0001391989,0.00006842859,0.000008698407,0.0000056913946,0.00016317652],"genre_scores_gemma":[0.99691576,0.00045653075,0.0018388182,0.00012989678,0.0005457983,0.0000023876191,0.000038003785,0.000011815448,0.000060964623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986037,0.00008461056,0.0005827042,0.0002884135,0.0001896892,0.0002509087],"domain_scores_gemma":[0.9990488,0.000036400557,0.00026770984,0.00016540459,0.0002300515,0.00025160942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008344847,0.0001853,0.000346625,0.000030493573,0.000036098038,0.000025161324,0.00019605157,0.0003356122,0.000035248213],"category_scores_gemma":[0.0008064681,0.0001320693,0.00013557482,0.00008027583,0.00006525546,0.0000057417624,0.0000958742,0.00026503415,0.0000014357847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000507553,0.0000680973,0.0003601183,0.000010132955,0.000038412232,0.00033206886,0.000024956706,0.00021033463,0.9973513,0.0000014145025,0.0003883839,0.0007072386],"study_design_scores_gemma":[0.0021690363,0.0005352899,0.00031939195,0.00006310039,0.00001842731,0.0021404005,0.00029938662,0.00010350938,0.9854748,0.0002812954,0.008350416,0.00024489805],"about_ca_topic_score_codex":0.000006032689,"about_ca_topic_score_gemma":9.645225e-7,"teacher_disagreement_score":0.011876442,"about_ca_system_score_codex":0.000028388647,"about_ca_system_score_gemma":0.00008321952,"threshold_uncertainty_score":0.53856295},"labels":[],"label_agreement":null},{"id":"W2117445095","doi":"10.1124/mol.107.043893","title":"Conformational Rearrangements and Signaling Cascades Involved in Ligand-Biased Mitogen-Activated Protein Kinase Signaling through the β1-Adrenergic Receptor","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"University of California, Riverside; Javna Agencija za Raziskovalno Dejavnost RS","keywords":"Protein kinase A; Signal transduction; Cell biology; Mitogen-activated protein kinase; Receptor; Chemistry; Signaling proteins; Kinase; Adrenergic receptor; Biology; Biochemistry","score_opus":0.020950013695614784,"score_gpt":0.2639409871703835,"score_spread":0.24299097347476872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117445095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951383,0.001502987,0.0018986147,0.00030796204,0.00028959292,0.0007085284,0.000017925217,0.000021116191,0.00011498064],"genre_scores_gemma":[0.9964368,0.00015159955,0.0012496569,0.0013952355,0.00019651462,0.00018989173,0.00020113222,0.00004105433,0.00013813918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99791324,0.0003860998,0.00050941407,0.00048442188,0.00026257292,0.00044425298],"domain_scores_gemma":[0.9993187,0.00003582854,0.00020759032,0.00021017826,0.000127658,0.00010001718],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004193235,0.00030004024,0.00029230272,0.00008472062,0.00028297197,0.000034485227,0.00026820254,0.00023697813,0.00030998877],"category_scores_gemma":[0.000060467122,0.0002522796,0.000115692754,0.0002123513,0.00017708162,0.000021667238,0.00013515895,0.0002686234,0.000010128995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026650127,0.00006605267,0.00012592955,0.000022275352,0.00012743864,0.000051395895,0.00058809656,0.0013735554,0.99664026,0.00008876764,0.0005051809,0.00014456324],"study_design_scores_gemma":[0.0020685226,0.0001909005,0.000028092083,0.000027530661,0.000028470282,0.000027778113,0.00027969052,0.0003452403,0.9897261,0.0001058718,0.0068754717,0.0002963109],"about_ca_topic_score_codex":0.000079769605,"about_ca_topic_score_gemma":0.0000060934112,"teacher_disagreement_score":0.0069141225,"about_ca_system_score_codex":0.000036317713,"about_ca_system_score_gemma":0.00012242676,"threshold_uncertainty_score":0.99999297},"labels":[],"label_agreement":null},{"id":"W2117701544","doi":"10.1073/pnas.1208881109","title":"β-Arrestin-2 mediates the proinflammatory effects of proteinase-activated receptor-2 in the airway","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Proinflammatory cytokine; Ovalbumin; Receptor; Airway resistance; Cytokine; Immunology; Chemistry; Biology; Inflammation; Cell biology; Endocrinology; Biochemistry; Asthma; Immune system","score_opus":0.018400834410243937,"score_gpt":0.26838151725797127,"score_spread":0.24998068284772734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117701544","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99764013,0.00053734606,0.0000015374848,0.00079124596,0.000033778677,0.0004085716,0.0000023638543,0.0000021225474,0.0005828867],"genre_scores_gemma":[0.9992965,0.000037051846,0.00035163405,0.00009841341,0.00013877069,0.000046393634,2.8404585e-7,0.0000037798768,0.000027180606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884754,0.00002873259,0.00023496605,0.0001291927,0.0006056523,0.00015391213],"domain_scores_gemma":[0.9993931,0.0001084836,0.0003432589,0.000014120331,0.00012201057,0.000019007713],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002148554,0.000081658305,0.0000994989,0.00004592574,0.00011169273,0.00000929886,0.00070533657,0.00008281858,0.000007003764],"category_scores_gemma":[0.0009046267,0.000037969734,0.000059353686,0.00033965465,0.00043559918,0.000027453494,0.000096300195,0.00012412635,4.4400622e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014442827,0.000036492795,0.003141296,0.000065381646,0.0000080917025,1.1792479e-9,0.0003047595,0.000013977733,0.99195355,0.0039704074,0.0002421124,0.0002494956],"study_design_scores_gemma":[0.00010760464,0.000067301225,0.009905294,0.000074440046,0.000005066415,0.0000017854411,0.00026754907,0.000027604581,0.9874604,0.0016527832,0.0003811923,0.00004903079],"about_ca_topic_score_codex":0.000004540632,"about_ca_topic_score_gemma":6.303392e-8,"teacher_disagreement_score":0.006763997,"about_ca_system_score_codex":0.0000075804583,"about_ca_system_score_gemma":0.000031279716,"threshold_uncertainty_score":0.16049834},"labels":[],"label_agreement":null},{"id":"W2118024111","doi":"10.1124/mol.58.2.373","title":"From Agonist To Antagonist: Fab Fragments of an Agonist-Like Monoclonal Anti-β<sub>2</sub>-Adrenoceptor Antibody Behave as Antagonists","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Agonist; Chemistry; Adenylyl cyclase; Monoclonal antibody; Receptor; Partial agonist; Molecular biology; Antibody; Biophysics; Biochemistry; Biology; Immunology","score_opus":0.00650766770309406,"score_gpt":0.2858949982614332,"score_spread":0.27938733055833914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118024111","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940996,0.0005736661,0.0022269513,0.00022472776,0.0011544582,0.00071731757,0.00047796144,0.00005725766,0.0004680642],"genre_scores_gemma":[0.9908852,0.00034750334,0.0025300342,0.0027421014,0.0006680127,0.000083892926,0.0024002613,0.0001379694,0.00020501431],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9961629,0.00034804482,0.00076858024,0.00134003,0.00047965767,0.00090076675],"domain_scores_gemma":[0.99825436,0.000020839578,0.00024803684,0.0007047903,0.00019509932,0.0005768486],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002812841,0.0006328581,0.00069551566,0.000155173,0.0002994448,0.000092283735,0.0008076165,0.0004986156,0.003236547],"category_scores_gemma":[0.000016912205,0.00070612336,0.0003500949,0.00026043755,0.00024299041,0.000023744728,0.00024999186,0.00031956343,0.00023358612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006493303,0.000605687,0.00019994623,0.000022197637,0.0003557869,0.00028841692,0.0001671775,0.00062833086,0.98726577,0.000023315575,0.0014475293,0.008346528],"study_design_scores_gemma":[0.0019149076,0.0013375668,0.00038690533,0.000020413625,0.00019691479,0.00007471335,0.00007798318,0.00022704073,0.97028136,0.000119558965,0.024638835,0.00072380254],"about_ca_topic_score_codex":0.00028996888,"about_ca_topic_score_gemma":0.0000135855635,"teacher_disagreement_score":0.023191307,"about_ca_system_score_codex":0.00006231526,"about_ca_system_score_gemma":0.00027122727,"threshold_uncertainty_score":0.999539},"labels":[],"label_agreement":null},{"id":"W2118169952","doi":"10.1161/01.res.0000176764.38934.86","title":"Heterodimerization of β <sub>1</sub> - and β <sub>2</sub> -Adrenergic Receptor Subtypes Optimizes β-Adrenergic Modulation of Cardiac Contractility","year":2005,"lang":"en","type":"article","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"National Institutes of Health; School of Medicine, Stanford University; Peking University; Heart and Stroke Foundation of Canada","keywords":"Agonist; Contractility; Receptor; Stimulation; Myocyte; Biology; Biophysics; Cell biology; Endocrinology; Population; Internal medicine; Colocalization; Adrenergic receptor; Chemistry; Biochemistry; Medicine","score_opus":0.02356474127199887,"score_gpt":0.28351994635884065,"score_spread":0.2599552050868418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118169952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99489117,0.00094245985,0.0034975172,0.000051637064,0.00011658574,0.00035383587,0.000034307275,0.000012629257,0.00009984467],"genre_scores_gemma":[0.99772435,0.0010818879,0.00046782402,0.000009921581,0.00022725225,0.000028746235,0.00042078225,0.000028555063,0.000010702606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99789655,0.0003953258,0.00047273777,0.00045702298,0.0004878754,0.00029047194],"domain_scores_gemma":[0.9986219,0.00007345478,0.00021475811,0.00035305184,0.0006294613,0.000107404085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010939515,0.00016416021,0.0002881272,0.00018507775,0.00014190104,0.000034984,0.000120205055,0.00026575304,0.00003040228],"category_scores_gemma":[0.00021786989,0.00015784238,0.0001218725,0.00027871827,0.00016993443,0.000035185225,0.00007765056,0.0001476173,0.0000040968057],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017100332,0.00006286314,0.002324966,0.000048531314,0.000054574226,1.1944526e-7,0.0000650478,0.037549578,0.9334155,0.00012355647,0.000033934197,0.026150355],"study_design_scores_gemma":[0.00036849786,0.00013878905,0.025624206,0.000027587068,0.000016611984,0.0000012195593,0.00004787511,0.015093381,0.95830685,0.00011059087,0.000116582465,0.00014783735],"about_ca_topic_score_codex":0.000037859565,"about_ca_topic_score_gemma":0.000014803829,"teacher_disagreement_score":0.026002519,"about_ca_system_score_codex":0.00003689028,"about_ca_system_score_gemma":0.00009670006,"threshold_uncertainty_score":0.6436626},"labels":[],"label_agreement":null},{"id":"W2118388731","doi":"10.1111/j.1471-4159.2005.03001.x","title":"Protection by cholesterol‐extracting cyclodextrins: a role for <i>N</i>‐methyl‐<scp>d</scp>‐aspartate receptor redistribution","year":2005,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Microstructural Sciences; Institute for Biological Sciences; National Research Council Canada","funders":"","keywords":"NMDA receptor; Neuroprotection; Glutamate receptor; Postsynaptic potential; Chemistry; Biochemistry; Postsynaptic density; Receptor; Biophysics; Biology; Pharmacology","score_opus":0.010051507396751997,"score_gpt":0.2394088287625592,"score_spread":0.2293573213658072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118388731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9689982,0.0008856227,0.02910703,0.00021279235,0.00029236695,0.00020990543,0.000054089513,0.000015031978,0.00022496984],"genre_scores_gemma":[0.99445707,0.00020805288,0.0023359696,0.00017731373,0.0018847858,0.00003093416,0.00010103132,0.000044700162,0.0007601653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847996,0.000049819362,0.0005844567,0.0003079899,0.00024950557,0.00032827666],"domain_scores_gemma":[0.99853647,0.000046658657,0.00073151116,0.00019413487,0.00032072078,0.00017050769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004680401,0.00022252115,0.00024014614,0.000037144164,0.00014090254,0.000073644886,0.00025104493,0.000247267,0.0000123713135],"category_scores_gemma":[0.0007346203,0.0002197626,0.0002551635,0.00008560174,0.000028149203,0.000029998726,0.000041395095,0.00033709704,0.0000032557869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008388724,0.000103164966,0.00002214323,0.000038022066,0.000044339085,0.0000011010345,0.00004008486,0.00015197134,0.9845417,0.0000018892205,0.009735056,0.0052365996],"study_design_scores_gemma":[0.00072509487,0.000328087,0.000020991938,0.000038816124,0.000028757146,0.00011273151,0.00014683201,0.00019730018,0.7800264,0.000031271727,0.21826275,0.00008098425],"about_ca_topic_score_codex":0.0000013542383,"about_ca_topic_score_gemma":5.182518e-7,"teacher_disagreement_score":0.2085277,"about_ca_system_score_codex":0.000054154945,"about_ca_system_score_gemma":0.00008162922,"threshold_uncertainty_score":0.89616585},"labels":[],"label_agreement":null},{"id":"W2118693119","doi":"10.1177/0091270006292163","title":"Drug‐Disease Interactions: Losartan Effect Is Not Downregulated by Rheumatoid Arthritis","year":2006,"lang":"en","type":"article","venue":"The Journal of Clinical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Losartan; Rheumatoid arthritis; Active metabolite; Pharmacology; Metabolite; Medicine; Arthritis; Inflammation; Pharmacokinetics; Internal medicine; Endocrinology; Angiotensin II; Chemistry; Receptor","score_opus":0.012671496766233704,"score_gpt":0.3470690022118119,"score_spread":0.3343975054455782,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118693119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901515,0.00414653,0.0006302721,0.0026489373,0.0021259373,0.000152242,0.000020903868,0.00000656199,0.00011711866],"genre_scores_gemma":[0.99066,0.0046005514,0.00008028477,0.002613517,0.0014823306,0.0000040283107,0.000017331446,0.000020290428,0.0005216263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99754125,0.0008479534,0.001034877,0.00017172059,0.00017701424,0.00022716532],"domain_scores_gemma":[0.998476,0.0003929272,0.0006245124,0.00016184073,0.00016488969,0.00017978015],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0018496542,0.00016007297,0.00038620277,0.00003737313,0.00011038632,0.000017713888,0.00031436284,0.00010880664,0.00114642],"category_scores_gemma":[0.00014790035,0.00010812274,0.00035278438,0.00006447473,0.00015012307,0.000009971402,0.00006879133,0.0004242971,0.000028567643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034227697,0.00017101124,0.00041696412,0.000005073185,0.00016420691,0.00001422004,0.00000996844,0.00015160342,0.6756532,0.0000075146986,0.31705645,0.002927019],"study_design_scores_gemma":[0.0033129533,0.0011401488,0.00049956696,0.000039768765,0.00011678573,0.000094308554,0.000015337782,0.00023661944,0.7846802,0.0002717848,0.20942494,0.00016759367],"about_ca_topic_score_codex":0.000015820053,"about_ca_topic_score_gemma":0.000004532245,"teacher_disagreement_score":0.10902698,"about_ca_system_score_codex":0.000010964958,"about_ca_system_score_gemma":0.000093059825,"threshold_uncertainty_score":0.99976665},"labels":[],"label_agreement":null},{"id":"W2118762668","doi":"10.1073/pnas.98.3.1230","title":"Odor-evoked calcium signals in dendrites of rat mitral cells","year":2001,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":144,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Dendritic spike; Odor; Neuroscience; Soma; Calcium; Intracellular; Biophysics; Calcium imaging; Biology; Calcium in biology; Lucifer yellow; Electrophysiology; Chemistry; Cell biology; Excitatory postsynaptic potential; Inhibitory postsynaptic potential; Gap junction","score_opus":0.03796152262059029,"score_gpt":0.29929750604996297,"score_spread":0.2613359834293727,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118762668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978349,0.00032718037,0.00000810722,0.0002614814,0.000023399924,0.000090528854,0.000004462692,0.0000014482268,0.0014484595],"genre_scores_gemma":[0.99840593,0.000082702114,0.0010441085,0.00009050736,0.000058457637,0.0000033959852,2.0783094e-7,0.0000028663428,0.00031183986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899745,0.000006895805,0.00024526817,0.00017566752,0.00044824474,0.00012644952],"domain_scores_gemma":[0.9995457,0.000025781015,0.00024205126,0.0000059244308,0.00015824189,0.00002231564],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007777536,0.0000696085,0.00012238795,0.00008771688,0.000046692825,0.0000074735976,0.0004485288,0.00009299316,0.000023141036],"category_scores_gemma":[0.0001454044,0.000049411035,0.00009323165,0.00033240527,0.00027540597,0.000016447375,0.000080788624,0.00006804606,2.7911554e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001858959,0.000027364964,0.004428571,0.000018647974,0.000007059694,4.8170317e-9,0.000037359623,0.0002462744,0.9936154,0.0012095706,0.00030692658,0.00008425993],"study_design_scores_gemma":[0.0001444226,0.00006585962,0.0026902796,0.00004845516,0.000004335049,0.000002710063,0.00010411359,0.00023906323,0.9917959,0.00453785,0.00031105216,0.000055962893],"about_ca_topic_score_codex":0.0000070769242,"about_ca_topic_score_gemma":2.333493e-7,"teacher_disagreement_score":0.0033282794,"about_ca_system_score_codex":0.000007211356,"about_ca_system_score_gemma":0.000027004606,"threshold_uncertainty_score":0.20149235},"labels":[],"label_agreement":null},{"id":"W2119208694","doi":"10.1002/syn.20627","title":"The neurokinin‐3 (NK<sub>3</sub>) and the neurokinin‐1 (NK<sub>1</sub>) receptors are differentially targeted to mesocortical and mesolimbic projection neurons and to neuronal nuclei in the rat ventral tegmental area","year":2009,"lang":"en","type":"article","venue":"Synapse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Heart, Lung, and Blood Institute","keywords":"Ventral tegmental area; Neuroscience; Nucleus accumbens; Receptor; Chemistry; Tachykinin receptor 1; Cell biology; Biology; Dopaminergic; Dopamine; Neuropeptide; Substance P; Biochemistry","score_opus":0.006912982082050407,"score_gpt":0.21296887443060444,"score_spread":0.20605589234855404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119208694","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99377215,0.00035855258,0.000139787,0.0040764534,0.00045737877,0.00111989,0.000021281086,0.000024842115,0.000029654611],"genre_scores_gemma":[0.9962213,0.00078339217,0.000029036088,0.0025704382,0.00021775496,0.00009677824,0.000027848453,0.00004009421,0.000013362771],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99738973,0.00055148616,0.0004092186,0.0007446669,0.00031588928,0.00058901776],"domain_scores_gemma":[0.9990473,0.00013354841,0.00012780922,0.00038651272,0.000050359773,0.00025449356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041287462,0.00038693473,0.00030755933,0.00007855436,0.00051438407,0.00027616817,0.0003127346,0.00016214012,0.000005542778],"category_scores_gemma":[0.00031323356,0.00023667848,0.00011417643,0.00023097616,0.00023400778,0.00001902621,0.00023492746,0.00040482986,0.0000027892934],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080849795,0.000091077374,0.0007454575,0.000009539522,0.000029365317,0.000021534068,0.00046096882,0.000027857473,0.9901334,0.00023111189,0.00090892235,0.006532291],"study_design_scores_gemma":[0.0030908247,0.0031957494,0.098822385,0.000066339904,0.00015062734,0.00033730475,0.0010086001,0.0009233082,0.88895714,0.000493452,0.0022225522,0.0007317214],"about_ca_topic_score_codex":0.000009547964,"about_ca_topic_score_gemma":0.00009486083,"teacher_disagreement_score":0.10117624,"about_ca_system_score_codex":0.000019427403,"about_ca_system_score_gemma":0.000052351872,"threshold_uncertainty_score":0.96514684},"labels":[],"label_agreement":null},{"id":"W2119220314","doi":"10.1523/jneurosci.1090-09.2009","title":"PSD-95 Is Essential for Hallucinogen and Atypical Antipsychotic Drug Actions at Serotonin Receptors","year":2009,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre","funders":"National Institute on Drug Abuse; Wellcome Trust; National Alliance for Research on Schizophrenia and Depression; National Center for Research Resources; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Mental Health; Case Comprehensive Cancer Center, Case Western Reserve University; University of North Carolina at Chapel Hill; National Institutes of Health; Case Western Reserve University","keywords":"Postsynaptic density; Postsynaptic potential; Serotonergic; Metabotropic receptor; 5-HT receptor; Neuroscience; Receptor; Pharmacology; Cell biology; Metabotropic glutamate receptor; Biology; 5-HT2A receptor; Serotonin; Long-term depression; Metabotropic glutamate receptor 7; AMPA receptor; Chemistry; Glutamate receptor; Biochemistry","score_opus":0.02113409661416144,"score_gpt":0.2934504662243827,"score_spread":0.27231636961022126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119220314","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900961,0.00028388744,0.007576765,0.0011225785,0.0007868006,0.00011052683,0.0000037761436,0.0000027749547,0.000016790806],"genre_scores_gemma":[0.99571747,0.0006680321,0.0019859378,0.00089706905,0.00025972677,0.0000013561345,9.560647e-7,0.0000074168365,0.00046202634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991892,0.000028511833,0.00022236245,0.00021660344,0.00016585818,0.00017745512],"domain_scores_gemma":[0.9995022,0.0000113725255,0.00016747846,0.00010960806,0.000085804066,0.00012355666],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020959158,0.00009350335,0.00012611962,0.000038289534,0.00017781285,0.00004618411,0.00017714837,0.00005530907,0.000019409455],"category_scores_gemma":[0.00007510701,0.00007797017,0.0001038275,0.000079612415,0.00005980595,0.000014297552,0.00003010612,0.00008573297,8.011077e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021427374,0.000038798717,0.0001671334,0.0000032020587,0.000002909484,0.0000024215733,0.00003863797,0.000043573316,0.99458337,0.000032167853,0.003756,0.0011175073],"study_design_scores_gemma":[0.00059383945,0.0009988117,0.004722925,0.000019786794,0.000020711519,0.0003069206,0.00003135083,0.00078528957,0.9429457,0.00030066643,0.049133316,0.00014064214],"about_ca_topic_score_codex":4.0372714e-7,"about_ca_topic_score_gemma":8.762003e-7,"teacher_disagreement_score":0.051637635,"about_ca_system_score_codex":0.000009644166,"about_ca_system_score_gemma":0.000041145726,"threshold_uncertainty_score":0.31795314},"labels":[],"label_agreement":null},{"id":"W2119546274","doi":"10.1111/j.1471-4159.2005.03561.x","title":"An aplysia dopamine<sub>1</sub>‐like receptor: molecular and functional characterization","year":2005,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Dopamine; Aplysia; Agonist; Neurotransmitter; Biology; Dopamine receptor; Endogenous agonist; Receptor; Internal medicine; Dopamine receptor D1; Endocrinology; Stimulation; Inhibitory postsynaptic potential; Cell biology; Neuroscience; Chemistry; Biochemistry; Medicine","score_opus":0.005467552579584036,"score_gpt":0.20558108767517447,"score_spread":0.20011353509559043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119546274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99028766,0.00022955905,0.009044191,0.00013842109,0.00019919104,0.00003854766,0.000008043821,0.0000064732176,0.000047913676],"genre_scores_gemma":[0.99736524,0.0002788544,0.00071501837,0.00040192858,0.0010556136,0.0000020665864,0.000109009205,0.000026524167,0.000045759694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990311,0.000038523434,0.00032922154,0.00022763398,0.00021594274,0.00015754403],"domain_scores_gemma":[0.999197,0.0000061103174,0.00027473224,0.00017244635,0.00018331817,0.0001663789],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015635167,0.00015800563,0.0001571751,0.00004110637,0.000059989612,0.000048885264,0.00012622048,0.00014057655,0.000044622804],"category_scores_gemma":[0.000037830458,0.00015379436,0.00009861878,0.000057487767,0.000033099128,0.00002216653,0.000035222685,0.00017086465,0.0000028994502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009242609,0.00006750358,0.000104427585,0.000013654,0.000030973137,0.000007975073,0.0000114015065,0.00012441477,0.9948405,0.000005926329,0.00022706701,0.0044737333],"study_design_scores_gemma":[0.0004122142,0.00022330551,0.0009371963,0.000015848265,0.00002455436,0.00031177842,0.000022996364,0.0001235644,0.98972166,0.000010195888,0.008044393,0.00015226929],"about_ca_topic_score_codex":1.2054784e-7,"about_ca_topic_score_gemma":1.3276902e-7,"teacher_disagreement_score":0.008329172,"about_ca_system_score_codex":0.000014761088,"about_ca_system_score_gemma":0.000059724796,"threshold_uncertainty_score":0.62715524},"labels":[],"label_agreement":null},{"id":"W2119990334","doi":"10.1530/jme-13-0238","title":"MOLECULAR EVOLUTION OF GPCRS: CRH/CRH receptors","year":2014,"lang":"en","type":"review","venue":"Journal of Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"","keywords":"G protein-coupled receptor; Receptor; Chemistry; Biochemistry","score_opus":0.0146874065669548,"score_gpt":0.2913141738921752,"score_spread":0.2766267673252204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2119990334","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0019831695,0.9542311,0.041687056,0.000019044544,0.0013292747,0.0003122097,0.000013358524,0.0000085491265,0.00041623326],"genre_scores_gemma":[0.006566701,0.9894724,0.0030688928,0.00006366488,0.0004939052,0.00001765065,0.00006464715,0.0001314221,0.000120716024],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99576235,0.0007973232,0.0018326434,0.00053392805,0.0004582012,0.0006155652],"domain_scores_gemma":[0.99611634,0.00004318973,0.0024212266,0.0007222969,0.000496366,0.0002006003],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00054796546,0.00062339887,0.0023396974,0.00054881553,0.000050278508,0.00002225649,0.00094213866,0.00079934206,0.000094867035],"category_scores_gemma":[0.00040049176,0.0005407455,0.0018388348,0.00026457477,0.00016367955,0.000007637686,0.00026804794,0.0006986513,0.00001687572],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014178781,0.00030446943,0.000009067218,0.0057210927,0.0028874222,0.0005499551,0.00003254225,0.00030239066,0.36873108,0.0059384555,0.002337952,0.6130438],"study_design_scores_gemma":[0.00057527615,0.0015158751,3.4558e-7,0.0017614489,0.0008918776,0.0015343048,0.000024294372,0.0000036049219,0.090535596,0.0004076889,0.9022879,0.00046177107],"about_ca_topic_score_codex":0.000008444695,"about_ca_topic_score_gemma":0.0000010711599,"teacher_disagreement_score":0.89994997,"about_ca_system_score_codex":0.00012319996,"about_ca_system_score_gemma":0.0005985532,"threshold_uncertainty_score":0.9997044},"labels":[],"label_agreement":null},{"id":"W2120067804","doi":"10.1210/mend.14.1.0407","title":"TRH-R2 Exhibits Similar Binding and Acute Signaling but Distinct Regulation and Anatomic Distribution Compared with TRH-R1","year":2000,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Internal medicine; Endocrinology; Biology; Thyrotropin-releasing hormone; Receptor; Stimulation; Agonist; Messenger RNA; Hormone; Gene; Biochemistry; Medicine","score_opus":0.006298262935698341,"score_gpt":0.21770848475097468,"score_spread":0.21141022181527633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120067804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.983067,0.00083094026,0.015403436,0.00013075632,0.000050574585,0.0002512785,0.00006938618,0.000036043068,0.00016059187],"genre_scores_gemma":[0.99769217,0.0002263755,0.0010476608,0.00009477879,0.000061584025,0.000025025494,0.0006578729,0.000035829144,0.00015868612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841213,0.0001162209,0.0002625014,0.0006126841,0.0001358428,0.00046061134],"domain_scores_gemma":[0.9994584,0.000015223856,0.00009562783,0.00025371867,0.00005496855,0.0001221178],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0000919687,0.00027903312,0.00029126523,0.000060221653,0.00020497662,0.000055254146,0.00010803605,0.00015447476,0.000112914386],"category_scores_gemma":[0.000016542677,0.0002613733,0.00005789926,0.000102641825,0.000149588,0.000011416185,0.00007330557,0.00014022306,0.0000053576755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025386093,0.000027307338,0.0007554943,0.000016140566,0.00013159022,0.00008181584,0.000033449796,0.00026427925,0.9914533,0.0004216994,0.00004499549,0.006516049],"study_design_scores_gemma":[0.0017719347,0.00048173234,0.0018106184,0.000035101202,0.00013371916,0.0005191796,0.000076229946,0.0014508833,0.9892421,0.00029205016,0.0037493014,0.00043718208],"about_ca_topic_score_codex":0.000024225148,"about_ca_topic_score_gemma":0.000011288854,"teacher_disagreement_score":0.014625194,"about_ca_system_score_codex":0.000024302399,"about_ca_system_score_gemma":0.000030399795,"threshold_uncertainty_score":0.99998385},"labels":[],"label_agreement":null},{"id":"W2120072474","doi":"10.1074/jbc.m411695200","title":"Internalization and Src Activity Regulate the Time Course of ERK Activation by Delta Opioid Receptor Ligands","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"MAPK/ERK pathway; Agonist; Proto-oncogene tyrosine-protein kinase Src; Internalization; Chemistry; Receptor; Stimulation; δ-opioid receptor; Phosphorylation; Kinase; Tyrosine kinase; Cell biology; Biophysics; Pharmacology; Endocrinology; Biochemistry; Biology","score_opus":0.007907122168793263,"score_gpt":0.2336959979973941,"score_spread":0.22578887582860083,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120072474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957159,0.0006707952,0.0031351165,0.00031783202,0.000033494267,0.000042119635,0.000018732886,0.0000027495605,0.0000632397],"genre_scores_gemma":[0.99849266,0.00054153934,0.0002903858,0.00008138744,0.00036068266,0.0000011657496,0.000037834245,0.000006657536,0.00018768967],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993657,0.00003207731,0.00026435687,0.0001288609,0.00010410179,0.00010493286],"domain_scores_gemma":[0.99928397,0.000027019209,0.00039388417,0.000106188774,0.00012922277,0.000059721227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031887862,0.00010885184,0.00016905036,0.000007736498,0.000044905097,0.000016566271,0.00015865623,0.00019949437,0.00014192895],"category_scores_gemma":[0.00010185611,0.000064752174,0.00008971034,0.000042319796,0.00008099796,0.000009282943,0.000055716304,0.00013498096,5.883713e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016801209,0.00006992305,0.0003991887,0.00000994085,0.00004634255,1.7582178e-7,0.000022044254,0.000025632327,0.9930343,0.000002329606,0.0013609377,0.0048611467],"study_design_scores_gemma":[0.00026965066,0.00020039802,0.00022866599,0.000037327438,0.0000117655,0.000021772576,0.000033176566,0.000136874,0.9932074,0.00005000175,0.0057238145,0.00007915924],"about_ca_topic_score_codex":0.0000012540155,"about_ca_topic_score_gemma":1.2667327e-7,"teacher_disagreement_score":0.0047819875,"about_ca_system_score_codex":0.000014673931,"about_ca_system_score_gemma":0.000030281873,"threshold_uncertainty_score":0.2640517},"labels":[],"label_agreement":null},{"id":"W2120224742","doi":"10.1152/ajpheart.00066.2005","title":"Upregulation of β-adrenergic receptors in heart failure due to volume overload","year":2005,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Heart and Stroke Foundation of Canada","keywords":"Internal medicine; Beta adrenergic receptor kinase; Endocrinology; Heart failure; Inotrope; G protein-coupled receptor kinase; Downregulation and upregulation; Adrenergic receptor; Receptor; Ex vivo; Pressure overload; Adrenergic; Volume overload; In vivo; Chemistry; Biology; G protein; Medicine; G protein-coupled receptor","score_opus":0.005382355143400187,"score_gpt":0.22245279906311743,"score_spread":0.21707044391971725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120224742","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99887836,0.00040879683,0.000036775564,0.0003445548,0.00021002123,0.00010212405,0.000004282686,0.000004457612,0.000010598672],"genre_scores_gemma":[0.9962945,0.00004139874,0.0024178086,0.000639774,0.0005434602,0.0000055023565,0.000013917569,0.000022814573,0.000020814385],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99838406,0.00024002772,0.00055614935,0.00037606768,0.00012592433,0.00031775696],"domain_scores_gemma":[0.9990461,0.000027520917,0.00036142737,0.00026470024,0.00014798365,0.00015230381],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029318262,0.00021292818,0.0006825768,0.00017323213,0.000052427324,0.000005545639,0.00017416704,0.00015157126,0.00012635873],"category_scores_gemma":[0.00003818008,0.00019699591,0.00019605887,0.00020980931,0.0002753052,0.000019114068,0.00007400627,0.00019727224,0.000007239249],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018560063,0.000076115095,0.0016867275,0.000011310957,0.000052518873,1.1476223e-7,0.00011840024,0.0038946373,0.9920363,0.000058723203,0.0009632385,0.00091631484],"study_design_scores_gemma":[0.0009322905,0.0026246551,0.62528765,0.00006335949,0.000032910448,0.00011708007,0.00050449657,0.0001974309,0.3436547,0.00047927166,0.025707236,0.00039894358],"about_ca_topic_score_codex":0.000031150226,"about_ca_topic_score_gemma":0.000015433272,"teacher_disagreement_score":0.6483816,"about_ca_system_score_codex":0.000026393238,"about_ca_system_score_gemma":0.000092521885,"threshold_uncertainty_score":0.803326},"labels":[],"label_agreement":null},{"id":"W2120365849","doi":"10.1074/jbc.m202386200","title":"Constitutive Agonist-independent CCR5 Oligomerization and Antibody-mediated Clustering Occurring at Physiological Levels of Receptors","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":204,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Receptor; Agonist; Biophysics; Cell biology; G protein-coupled receptor; Biochemistry; Chemistry; Biology","score_opus":0.03254567076883377,"score_gpt":0.2618837388493296,"score_spread":0.2293380680804958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120365849","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959306,0.0010506824,0.0023665014,0.00002643167,0.00014008318,0.0000593284,0.000029267803,0.0000059873914,0.00039112053],"genre_scores_gemma":[0.9979134,0.0010543074,0.0006560656,0.00006178891,0.00021772263,0.0000013513195,0.000030258718,0.000007647005,0.000057448076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988533,0.000055909684,0.0004915361,0.00024036647,0.00015387789,0.00020497547],"domain_scores_gemma":[0.99913013,0.000038196584,0.00045912067,0.00010860311,0.00013289569,0.00013104151],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022896181,0.00017639111,0.00034366036,0.000022328448,0.00007962487,0.000014428979,0.00016727862,0.00031598902,0.00055929396],"category_scores_gemma":[0.00030778488,0.00012763691,0.00014255414,0.00006914498,0.00021680874,0.0000075070984,0.00017113176,0.00017838345,0.0000019628615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000853264,0.00006651732,0.0024618101,0.000030487752,0.00005650234,0.000009702264,0.000026891887,0.000095508854,0.9964287,0.0000045514794,0.00004592265,0.0006880592],"study_design_scores_gemma":[0.00059828936,0.00038223024,0.001564227,0.000056612073,0.000016181368,0.00014355815,0.00010732714,0.00021229275,0.99558014,0.000028973742,0.0011376396,0.00017250444],"about_ca_topic_score_codex":8.7231945e-7,"about_ca_topic_score_gemma":2.1744201e-7,"teacher_disagreement_score":0.0019828132,"about_ca_system_score_codex":0.000028720318,"about_ca_system_score_gemma":0.00001872307,"threshold_uncertainty_score":0.61238766},"labels":[],"label_agreement":null},{"id":"W2120446433","doi":"10.1016/j.bpj.2015.08.028","title":"Can Specific Protein-Lipid Interactions Stabilize an Active State of the Beta 2 Adrenergic Receptor?","year":2015,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto; Government of Ontario; Canada Foundation for Innovation; Ontario Research Foundation; University of Texas at Austin; National Science Foundation","keywords":"Adrenergic receptor; BETA (programming language); Beta-1 adrenergic receptor; Chemistry; Receptor; Alpha-1B adrenergic receptor; Alpha-1A adrenergic receptor; Adrenergic; Biophysics; Beta-3 adrenergic receptor; Biology; Biochemistry; Computer science","score_opus":0.023072651547406304,"score_gpt":0.25692739577717366,"score_spread":0.23385474422976735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120446433","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980638,0.00002792281,0.0007138267,0.00022457613,0.0006182168,0.00013193877,0.000037498598,0.000004864216,0.00017736774],"genre_scores_gemma":[0.99805605,0.000023621446,0.0005714196,0.00003369659,0.0009880816,0.0000071007084,0.000016883925,0.00001950172,0.0002836698],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894845,0.00017239741,0.00023718172,0.00019905686,0.00024461644,0.0001983158],"domain_scores_gemma":[0.99907404,0.0000061823857,0.00020364615,0.0002661012,0.00023788768,0.0002121491],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015402325,0.00013508117,0.00015274825,0.00002582796,0.00011096658,0.00004216716,0.00028454818,0.00004950091,0.00007439574],"category_scores_gemma":[0.000025615565,0.000090495676,0.00016042551,0.00010306672,0.00008914713,0.000012603886,0.00008625377,0.00023915975,0.000005065364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014949412,0.00013728219,0.000019251469,0.000002229478,0.00003796887,8.0850515e-7,0.00017953872,0.00014629327,0.9946714,0.00014418487,0.0003423029,0.004169264],"study_design_scores_gemma":[0.00034704583,0.00045317708,0.00012622486,0.00002028777,0.000009580188,0.000018134673,0.00030763797,0.00003990204,0.9881806,0.00034353486,0.010032914,0.000120964236],"about_ca_topic_score_codex":0.000014135992,"about_ca_topic_score_gemma":0.000016022945,"teacher_disagreement_score":0.009690611,"about_ca_system_score_codex":0.000043275246,"about_ca_system_score_gemma":0.00015023541,"threshold_uncertainty_score":0.36903065},"labels":[],"label_agreement":null},{"id":"W2120809213","doi":"10.1016/j.pep.2013.04.004","title":"Expression, purification and preliminary characterization of glucagon receptor extracellular domain","year":2013,"lang":"en","type":"article","venue":"Protein Expression and Purification","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Glucagon receptor; Fusion protein; G protein-coupled receptor; Biochemistry; Glucagon; Receptor; Glucose homeostasis; Glucagon-like peptide 1 receptor; Biology; Chemistry; Endocrinology; Agonist; Recombinant DNA; Insulin; Hormone; Gene","score_opus":0.007601106293689376,"score_gpt":0.20901661564727128,"score_spread":0.2014155093535819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120809213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9614956,0.0012121937,0.03601651,0.00020593026,0.000055751178,0.00093092874,0.000009800316,0.00001720301,0.000056089626],"genre_scores_gemma":[0.9847933,0.00045895224,0.013120056,0.000020311776,0.00010342687,0.00039089305,0.0004061886,0.000022381753,0.0006844668],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988688,0.00013352242,0.00032578412,0.00038684398,0.000145991,0.00013902214],"domain_scores_gemma":[0.9992145,0.000008716799,0.00026146785,0.0002886101,0.00013172852,0.00009499717],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002466336,0.00015059764,0.00013305171,0.000059654576,0.00012866211,0.000045876088,0.00009853746,0.00020507678,0.00019606175],"category_scores_gemma":[0.000050673458,0.00013166596,0.0000307437,0.00006240837,0.000058203976,0.00003683522,0.000056335837,0.00007252618,0.000008532924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008281456,0.000059023234,0.00011946797,0.00006829573,0.0000043155273,5.97681e-8,0.00022474074,8.7993567e-7,0.98767406,0.00024406766,0.000106578074,0.011415705],"study_design_scores_gemma":[0.0003013886,0.0001713273,0.0017725317,0.00012060249,0.0000045861607,0.000002175839,0.00017647534,0.00010844062,0.99058497,0.00044407902,0.006158689,0.00015472532],"about_ca_topic_score_codex":0.000006694941,"about_ca_topic_score_gemma":9.4257864e-8,"teacher_disagreement_score":0.023297729,"about_ca_system_score_codex":0.000005285487,"about_ca_system_score_gemma":0.00001731168,"threshold_uncertainty_score":0.5369182},"labels":[],"label_agreement":null},{"id":"W2120931193","doi":"10.1124/jpet.112.198564","title":"Differential Effects of Nicotine Treatment and Ethanol Self-Administration on CYP2A6, CYP2B6 and Nicotine Pharmacokinetics in African Green Monkeys","year":2012,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Nicotine; CYP2A6; CYP2B6; Pharmacology; Bupropion; Pharmacokinetics; Chemistry; Ethanol; Metabolism; In vivo; Drug metabolism; Smoking cessation; Endocrinology; Internal medicine; Biochemistry; Medicine; Biology; Cytochrome P450; CYP3A4","score_opus":0.013016853426464131,"score_gpt":0.30548011060110125,"score_spread":0.2924632571746371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120931193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935828,0.005672243,0.00006231333,0.00013820034,0.00035002126,0.00016307559,0.000003248753,0.0000024385338,0.000025700954],"genre_scores_gemma":[0.99575204,0.0033915632,0.00027611761,0.00022013065,0.0003143882,0.000006364767,0.0000037280654,0.0000136226245,0.000022054366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992245,0.00011750588,0.0002799861,0.00012252122,0.00007831118,0.00017717305],"domain_scores_gemma":[0.9995989,0.000041453182,0.00019675266,0.000043942928,0.000025776177,0.00009314257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083503604,0.00016438629,0.0002376269,0.00006773026,0.00004022859,0.000007872843,0.000051269013,0.00011000611,0.00002581064],"category_scores_gemma":[0.0000018179679,0.00013178584,0.000045548783,0.000034207336,0.00006944276,0.000011347692,0.000036713536,0.0001083083,1.5658887e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080865994,0.00081743445,0.0017897284,0.000027308693,0.00023101312,0.0000027936414,0.00077758706,0.000003532817,0.99280167,0.000026614161,0.000013255441,0.002700385],"study_design_scores_gemma":[0.0035888662,0.004337545,0.00042459878,0.000013618537,0.00015425532,0.00006191737,0.00017066901,0.00012030797,0.99017674,0.000013303908,0.00082408084,0.00011410455],"about_ca_topic_score_codex":0.0000036510328,"about_ca_topic_score_gemma":6.4003274e-7,"teacher_disagreement_score":0.0035201104,"about_ca_system_score_codex":0.000024013476,"about_ca_system_score_gemma":0.000024316754,"threshold_uncertainty_score":0.53740704},"labels":[],"label_agreement":null},{"id":"W2121052402","doi":"10.1160/th13-08-0672","title":"A novel thromboxane A2 receptor N42S variant results in reduced surface expression and platelet dysfunction","year":2014,"lang":"en","type":"article","venue":"Thrombosis and Haemostasis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; British Heart Foundation; Wellcome Trust","keywords":"Thromboxane receptor; Platelet; Thromboxane; Thromboxane A2; Receptor; Endocrinology; Internal medicine; G protein-coupled receptor; Platelet activation; Biology; Receptor expression; Medicine","score_opus":0.030202206906202927,"score_gpt":0.2663011293129143,"score_spread":0.23609892240671135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121052402","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99537295,0.00028168617,0.0029928691,0.0004275665,0.00020344512,0.00020719727,0.000056904024,0.000018392639,0.00043898402],"genre_scores_gemma":[0.9898729,0.0014519305,0.008108282,0.00015321978,0.00013275647,0.000009697216,0.0001488051,0.00002916291,0.000093273855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985878,0.00009020148,0.00032279544,0.00057922374,0.00014082543,0.00027917855],"domain_scores_gemma":[0.99940044,0.000036138503,0.00011875453,0.00027840128,0.000048561855,0.000117683245],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057424314,0.00022066287,0.0003034984,0.000047071386,0.0001500748,0.000061678635,0.00008916227,0.00023688747,0.000059192902],"category_scores_gemma":[0.00009126091,0.0001950914,0.00004534123,0.000100741796,0.00006503005,0.00001474909,0.000116876465,0.00012134099,0.000003840493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002090458,0.00007020163,0.00010653783,0.000021506088,0.000027054837,4.320704e-7,0.00023314418,0.000052126412,0.99112916,0.00016510517,0.0009892487,0.0069964607],"study_design_scores_gemma":[0.0025983786,0.00043069202,0.0027709166,0.00011564884,0.000020532792,0.0000130751305,0.00024330129,0.00043267867,0.9821356,0.00009358646,0.010817093,0.0003284903],"about_ca_topic_score_codex":0.0001654191,"about_ca_topic_score_gemma":0.000037894613,"teacher_disagreement_score":0.009827844,"about_ca_system_score_codex":0.000011372623,"about_ca_system_score_gemma":0.00002126611,"threshold_uncertainty_score":0.79555964},"labels":[],"label_agreement":null},{"id":"W2121058501","doi":"10.1016/s0022-3565(24)38985-2","title":"Pharmacological and Molecular Characterization of Muscarinic Receptor Subtypes in Human Esophageal Smooth Muscle","year":2000,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Methoctramine; Muscarinic acetylcholine receptor; Pirenzepine; Carbachol; Internal medicine; Muscarinic antagonist; Endocrinology; Biology; Receptor; Muscarinic acetylcholine receptor M2; Receptor antagonist; Muscle contraction; Muscarinic acetylcholine receptor M3; Antagonist; Medicine","score_opus":0.013922458831495883,"score_gpt":0.3051446705922567,"score_spread":0.2912222117607608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121058501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967598,0.0028044842,0.000039805465,0.00008129222,0.00016180523,0.000094368916,0.000003891783,0.000002033367,0.000052537256],"genre_scores_gemma":[0.99726754,0.0016705978,0.00019222978,0.0006782957,0.00012986557,0.0000035513517,0.000009132475,0.000011126503,0.000037648497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992248,0.000119888166,0.00031463613,0.00013289803,0.00007659211,0.00013120874],"domain_scores_gemma":[0.99972796,0.000008821696,0.0001465345,0.000035799836,0.000030377378,0.000050497063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019650694,0.00011256561,0.00019374912,0.00005262512,0.000044674827,0.00000831376,0.000085709966,0.00012140303,0.000658647],"category_scores_gemma":[0.000001060969,0.00009996079,0.000051961244,0.000046706027,0.00010513718,0.000011840539,0.000030028925,0.0001288516,4.59893e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003699757,0.00021522124,0.00034637452,0.000006212411,0.00007950041,0.000009927823,0.00021058014,0.00001388894,0.99475884,0.000027907618,0.000016067956,0.003945508],"study_design_scores_gemma":[0.0015758781,0.0009637826,0.0013259114,0.000007089183,0.00004371356,0.00001916525,0.000080510465,0.000059862257,0.9925866,0.00003065677,0.0032143623,0.000092459166],"about_ca_topic_score_codex":0.0000016854187,"about_ca_topic_score_gemma":1.7765045e-7,"teacher_disagreement_score":0.003853049,"about_ca_system_score_codex":0.000012030408,"about_ca_system_score_gemma":0.00002297151,"threshold_uncertainty_score":0.7211722},"labels":[],"label_agreement":null},{"id":"W2121297175","doi":"10.2174/157340906778226409","title":"An Introduction to Molecular Modeling of G-Protein Coupled Receptors","year":2006,"lang":"en","type":"article","venue":"Current Computer - Aided Drug Design","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Rhodopsin; Homology modeling; Metabotropic glutamate receptor; Rhodopsin-like receptors; Computational biology; Class C GPCR; Metabotropic glutamate receptor 1; Biology; Chemistry; Metabotropic receptor; Receptor; Biochemistry; Glutamate receptor; Retinal","score_opus":0.01305446921667927,"score_gpt":0.24446517412461968,"score_spread":0.2314107049079404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121297175","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.39786667,0.00033146195,0.6008316,0.00007347404,0.0005959362,0.00027412394,0.0000018164391,0.0000210042,0.000003868781],"genre_scores_gemma":[0.90733653,0.0000108531485,0.09072101,0.000038301427,0.001644666,0.000033772652,0.0001501675,0.000036414473,0.000028255832],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983855,0.00017582954,0.00038942829,0.000564004,0.00021372459,0.00027153583],"domain_scores_gemma":[0.99914294,0.000005938829,0.000107427,0.0004394018,0.00019417243,0.00011010629],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004250035,0.00022051734,0.00022610619,0.00010746257,0.000067059605,0.000041825937,0.00026888613,0.00008356954,0.000033477783],"category_scores_gemma":[0.000014420112,0.00022592735,0.00010615428,0.0001556957,0.000021450736,0.000011186694,0.000071932605,0.000098950804,0.000007912842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051927767,0.000086362474,0.000004789139,0.000014282276,0.000012092954,5.280104e-7,0.000028206769,0.32463035,0.6681668,0.00048006,0.0013071562,0.005217436],"study_design_scores_gemma":[0.00029598267,0.00025074338,0.0000020126713,0.000028810153,0.000012491077,0.0000017910578,0.000013047014,0.30806527,0.6886915,0.00057646463,0.001826637,0.00023528369],"about_ca_topic_score_codex":0.000028025448,"about_ca_topic_score_gemma":0.0000014970877,"teacher_disagreement_score":0.5101106,"about_ca_system_score_codex":0.000022202215,"about_ca_system_score_gemma":0.000054094297,"threshold_uncertainty_score":0.921305},"labels":[],"label_agreement":null},{"id":"W2121517459","doi":"10.1210/mend.15.2.0598","title":"Human Angiotensin II Type 1 Receptor Isoforms Encoded by Messenger RNA Splice Variants Are Functionally Distinct","year":2001,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; U.S. Public Health Service; Université de Sherbrooke; Brigham Young University","keywords":"Biology; Gene isoform; splice; Messenger RNA; Alternative splicing; Molecular biology; Receptor; Angiotensin II; RNA splicing; RNA; Cell biology; Gene; Genetics","score_opus":0.01056332934119436,"score_gpt":0.23992890112685972,"score_spread":0.22936557178566536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121517459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98823255,0.0016129608,0.0066681807,0.00057978695,0.00061951275,0.000229649,0.000032824748,0.000062425344,0.0019621039],"genre_scores_gemma":[0.99262905,0.00020818826,0.0011281407,0.0009541867,0.00029580673,0.000030043659,0.0005425238,0.00007064048,0.004141435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99792045,0.000109607834,0.00034363937,0.0007215998,0.0002140535,0.0006906264],"domain_scores_gemma":[0.9989184,0.000008738976,0.00017320357,0.0005376123,0.00021116615,0.00015086375],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011290053,0.00034079837,0.00031901072,0.00008186309,0.00032582067,0.000023764223,0.00032231587,0.0002849093,0.0010837404],"category_scores_gemma":[0.00007351681,0.0003279331,0.00017028228,0.00018700592,0.000095778174,0.0000087473145,0.00025909324,0.0002248591,0.00009594599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009800601,0.00012433829,0.0002854384,0.0000057002553,0.00014658453,0.000088851906,0.000020768512,0.000036444588,0.9800352,0.00052220793,0.01785067,0.0007858305],"study_design_scores_gemma":[0.0009083621,0.00072485,0.0007304784,0.000014430184,0.00004642221,0.00020489689,0.00007213485,0.00003482672,0.7950282,0.00028951268,0.20145273,0.00049313245],"about_ca_topic_score_codex":0.00006071679,"about_ca_topic_score_gemma":0.000029837172,"teacher_disagreement_score":0.18500695,"about_ca_system_score_codex":0.000033901735,"about_ca_system_score_gemma":0.000052578256,"threshold_uncertainty_score":0.99991727},"labels":[],"label_agreement":null},{"id":"W2121775582","doi":"10.1139/y02-046","title":"Relevant role of Leu<sup>265</sup>in helix VI of the angiotensin AT<sub>1</sub>receptor in agonist binding and activity","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Chinese hamster ovary cell; Receptor; Mutant; Agonist; Transmembrane domain; Inositol phosphate; Chemistry; Angiotensin II; Binding site; Biochemistry; Stereochemistry; Molecular biology; Biology; Inositol; Gene","score_opus":0.008581956310394089,"score_gpt":0.21540660580238183,"score_spread":0.20682464949198773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121775582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970594,0.0022603283,0.0000038084568,0.00031875726,0.000205777,0.00009528974,0.000029256911,5.468551e-7,0.00002681688],"genre_scores_gemma":[0.9988531,0.0008203197,0.000038093214,0.000144089,0.000111579604,0.0000017000831,0.000003067495,0.00001029693,0.000017789283],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989576,0.00024517108,0.00030216805,0.00017795622,0.000046294655,0.0002708466],"domain_scores_gemma":[0.99940026,0.000048464823,0.00025264802,0.00008606383,0.00006178381,0.00015076759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025589435,0.00012721184,0.0003202546,0.0001432499,0.00008078749,0.0000032630185,0.00013610611,0.00020690745,0.00019467346],"category_scores_gemma":[0.000036222144,0.00010566121,0.000083038416,0.000106679676,0.0002804115,0.000008549441,0.000047982212,0.00024061433,8.581508e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000118475444,0.000029956209,0.0036758664,0.00002432888,0.000052906984,0.000009883067,0.0002783724,0.0003663603,0.99374366,0.000017583507,0.00036793237,0.0013146771],"study_design_scores_gemma":[0.00078553957,0.00029917486,0.0054792454,0.000029672989,0.000024517894,0.00007037999,0.00008585831,0.00046937994,0.9914515,0.00011780476,0.0010888152,0.00009812478],"about_ca_topic_score_codex":0.00028410362,"about_ca_topic_score_gemma":0.001312242,"teacher_disagreement_score":0.002292171,"about_ca_system_score_codex":0.000037200945,"about_ca_system_score_gemma":0.00014630583,"threshold_uncertainty_score":0.4308739},"labels":[],"label_agreement":null},{"id":"W2121872275","doi":"10.1124/jpet.103.055327","title":"Muscarinic Agonist-Mediated Heterologous Desensitization in Isolated Ileum Requires Activation of Both Muscarinic M2 and M3 Receptors","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Muscarinic acetylcholine receptor; Oxotremorine; Muscarinic agonist; Agonist; Endocrinology; Internal medicine; Muscarinic acetylcholine receptor M4; Acetylcholine; Muscarinic acetylcholine receptor M1; Muscarinic acetylcholine receptor M3; Chemistry; Homologous desensitization; Muscarinic acetylcholine receptor M2; Receptor; Desensitization (medicine); Muscarinic acetylcholine receptor M5; Biology; Pharmacology; Medicine","score_opus":0.01496676799672579,"score_gpt":0.2953723548149966,"score_spread":0.28040558681827077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121872275","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99663085,0.001998841,0.00076310075,0.00012319809,0.000362874,0.00010127616,0.0000018919562,0.0000031843967,0.000014797996],"genre_scores_gemma":[0.9975279,0.0014383598,0.00033820895,0.00055517384,0.0001017041,0.0000024964065,0.000014722326,0.000013702188,0.00000775714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919075,0.000085289736,0.00036558145,0.0001375587,0.00007945964,0.00014135533],"domain_scores_gemma":[0.9995541,0.000023144277,0.00027310016,0.000046716727,0.000056694673,0.000046241723],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021092455,0.000121838406,0.00020183314,0.00009275629,0.000050949406,0.000008922714,0.00006513336,0.00017872984,0.000026884676],"category_scores_gemma":[0.000007246285,0.0001111308,0.00004866855,0.00006965674,0.00011111802,0.000017842694,0.000040154227,0.0001439243,2.418831e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007669582,0.00015120736,0.0006487545,0.0000085670545,0.00012272394,0.000004951908,0.00057947065,0.0005168008,0.9965385,0.000021342474,0.000014301516,0.0006263729],"study_design_scores_gemma":[0.0024343054,0.0016163609,0.00037488504,0.00001983078,0.000035867313,0.00006558154,0.00036453758,0.00026406045,0.9942144,0.0001304433,0.00037586546,0.0001038367],"about_ca_topic_score_codex":0.00001254266,"about_ca_topic_score_gemma":0.0000033989104,"teacher_disagreement_score":0.0023241232,"about_ca_system_score_codex":0.00003056778,"about_ca_system_score_gemma":0.000060492657,"threshold_uncertainty_score":0.45317826},"labels":[],"label_agreement":null},{"id":"W2122031040","doi":"10.1016/s0378-5173(00)00430-0","title":"Pharmacokinetics of metoprolol enantiomers following single and multiple administration of racemate in rat","year":2000,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Enantiomer; Pharmacokinetics; Oral administration; Metoprolol; Pharmacology; Chemistry; Stereospecificity; Absorption (acoustics); High-performance liquid chromatography; Dosing; Chromatography; Medicine; Stereochemistry; Internal medicine; Biochemistry","score_opus":0.020596801256865138,"score_gpt":0.32609790700667424,"score_spread":0.3055011057498091,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122031040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976722,0.0008370319,0.00081035803,0.0000824297,0.00042762246,0.000061378436,0.000009509902,9.772223e-7,0.000098514814],"genre_scores_gemma":[0.99689126,0.0010806012,0.0017842493,0.000054771852,0.00011877835,5.042531e-7,0.000008672574,0.000008654711,0.000052480653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990778,0.000045020846,0.00047542856,0.00008299872,0.00023464093,0.000084143656],"domain_scores_gemma":[0.9994341,0.000027571043,0.00028103866,0.000044873468,0.00016878528,0.000043621974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003186497,0.00007865351,0.00015155147,0.00010139131,0.000009866706,0.000010960368,0.00014917915,0.000050923863,0.000091943],"category_scores_gemma":[0.000052706495,0.000073948555,0.00009593599,0.000054906548,0.000031921,0.0000141136015,0.000023574705,0.00008068227,2.9180032e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050236454,0.00013129957,0.0020879642,0.000014287217,0.00013479518,0.000020447073,0.00009801131,0.0012475762,0.98191905,0.000009518606,0.000013434695,0.013821244],"study_design_scores_gemma":[0.0016417776,0.00021760631,0.00010351538,0.000051790335,0.000039793274,0.00006155345,0.00006645844,0.0016177804,0.9917802,0.000043163538,0.00431206,0.00006429887],"about_ca_topic_score_codex":0.0000027952076,"about_ca_topic_score_gemma":0.0000021099786,"teacher_disagreement_score":0.013756946,"about_ca_system_score_codex":0.000012921358,"about_ca_system_score_gemma":0.000046539986,"threshold_uncertainty_score":0.30155346},"labels":[],"label_agreement":null},{"id":"W2122146139","doi":"10.1124/mol.58.1.120","title":"Inhibition of Cell Surface Expression by Mutant Receptors Demonstrates that D2 Dopamine Receptors Exist as Oligomers in the Cell","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Mutant; Receptor; Cell biology; Wild type; 5-HT5A receptor; Biology; Dopamine receptor; G protein-coupled receptor; HEK 293 cells; Cell; Gene; Biochemistry; Chemistry","score_opus":0.0072587969378901844,"score_gpt":0.24378114250998295,"score_spread":0.23652234557209276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122146139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925024,0.0014393922,0.00034498778,0.00014728558,0.00033786893,0.000420563,0.00002086363,0.000013570111,0.0047730654],"genre_scores_gemma":[0.996706,0.0011739419,0.00056556263,0.0006272249,0.000062313586,0.000036922593,0.00023673647,0.000041313302,0.000549951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979378,0.00049955543,0.00038723822,0.0005030603,0.00024530504,0.00042707068],"domain_scores_gemma":[0.99939626,0.000035803343,0.00017058753,0.00025144964,0.000047273836,0.00009860806],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00041559272,0.00029091732,0.00026724656,0.000059028174,0.000090988,0.000020154477,0.00031186233,0.00028085735,0.0024960188],"category_scores_gemma":[0.0000083444975,0.00024397076,0.000143049,0.0001709209,0.00014278645,0.000010603916,0.00005956388,0.0002448732,0.00003523311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017858428,0.00026357142,0.000102997765,0.000029294744,0.00001728975,0.000026814796,0.00017032167,0.00071977405,0.99435985,0.000007184567,0.0035824936,0.0005418296],"study_design_scores_gemma":[0.0011597394,0.0004234448,0.0000052789383,0.000018475272,0.00003428537,0.00001400516,0.00047050466,0.000040773055,0.9827281,0.00004755826,0.014795331,0.00026246437],"about_ca_topic_score_codex":0.000057440386,"about_ca_topic_score_gemma":0.000003095415,"teacher_disagreement_score":0.011631705,"about_ca_system_score_codex":0.000026374446,"about_ca_system_score_gemma":0.000060353475,"threshold_uncertainty_score":0.9984158},"labels":[],"label_agreement":null},{"id":"W2122682542","doi":"10.1038/nchembio.307","title":"Rapid behavior-based identification of neuroactive small molecules in the zebrafish","year":2010,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":540,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Canada's Michael Smith Genome Sciences Centre","funders":"National Institute of General Medical Sciences; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Heart, Lung, and Blood Institute","keywords":"Zebrafish; Neuroactive steroid; Drug discovery; Computational biology; Neuroscience; Small molecule; Biology; Identification (biology); Bioinformatics; Biochemistry; Gene","score_opus":0.007860714173641531,"score_gpt":0.25095645399062505,"score_spread":0.2430957398169835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122682542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998548,0.00022352926,0.0004909469,0.00017270475,0.00022054247,0.00016907619,0.00002295009,0.0000053818053,0.0001468703],"genre_scores_gemma":[0.9982509,0.000010449042,0.00094129593,0.00043297673,0.00012252612,0.000038564773,0.00019015343,0.000009789972,0.0000033220042],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920964,0.00008113025,0.00021677534,0.00028646764,0.00005316138,0.0001528116],"domain_scores_gemma":[0.9994641,0.000047168796,0.000104182865,0.0002832757,0.000074274285,0.000026978103],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002551872,0.00011007657,0.00012193071,0.00003699724,0.000024048813,0.000008310173,0.00028942106,0.00066188327,0.000044323853],"category_scores_gemma":[0.00021264299,0.00007967895,0.00008577906,0.00009753108,0.00011399473,0.000001463075,0.000037686994,0.0005542754,0.0000012447728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042656033,0.00008343839,0.00046632657,0.0000044112508,0.000006224147,0.000006969085,0.000017822304,0.0000011786236,0.9957698,0.0006550264,0.00003462876,0.0029115449],"study_design_scores_gemma":[0.00024753128,0.000096190684,0.00064927305,0.0000013521484,0.000012193623,0.00005038807,0.000034304092,0.000042725685,0.99671197,0.00024607225,0.0018198416,0.000088150824],"about_ca_topic_score_codex":0.000008444228,"about_ca_topic_score_gemma":0.000015482805,"teacher_disagreement_score":0.002823394,"about_ca_system_score_codex":0.0000033302144,"about_ca_system_score_gemma":0.000026771831,"threshold_uncertainty_score":0.510505},"labels":[],"label_agreement":null},{"id":"W2123132081","doi":"10.1139/y10-057","title":"ET<sub>A</sub> receptors are present in human aortic vascular endothelial cells and modulate intracellular calciumThis article is one of a selection of papers published in the two-part special issue entitled 20 Years of Endothelin Research.","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Intracellular; Cytosol; Biology; Vascular smooth muscle; Calcium in biology; Molecular biology; Western blot; Cell biology; Endocrinology; Biochemistry","score_opus":0.013060583489136374,"score_gpt":0.27212092360737644,"score_spread":0.2590603401182401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123132081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990021,0.0001870771,0.0000037057428,0.00018683815,0.0003921722,0.00016294251,0.00002497669,4.1995108e-7,0.000039794017],"genre_scores_gemma":[0.9989323,0.00027425564,0.000040823652,0.0000808724,0.0006377356,0.0000046231185,0.0000045090965,0.000008873061,0.000016030242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998615,0.00048741544,0.00039537522,0.00016583153,0.00010073856,0.00023562273],"domain_scores_gemma":[0.99935615,0.00007075325,0.00022684093,0.00009176943,0.00014140096,0.000113084185],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011131073,0.00008590355,0.0002730492,0.00021658394,0.00004282797,0.0000068388863,0.00015327966,0.0001568461,0.0028473765],"category_scores_gemma":[0.00006608111,0.000077879435,0.00006480609,0.00013184533,0.0003059093,0.000012631179,0.000024914545,0.00042924212,4.6637354e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000114118426,0.00007392647,0.0009116055,0.000033947374,0.000079991536,0.000006127331,0.0007883629,0.00014230475,0.9966516,0.000036985704,0.0005325213,0.0006285343],"study_design_scores_gemma":[0.0010703019,0.00033493582,0.0017348251,0.000015610905,0.00002944469,0.0000068241684,0.00016763521,0.00007634485,0.99326646,0.00042567827,0.002809082,0.00006288243],"about_ca_topic_score_codex":0.0007874446,"about_ca_topic_score_gemma":0.0035662362,"teacher_disagreement_score":0.0033851394,"about_ca_system_score_codex":0.0000123032005,"about_ca_system_score_gemma":0.0001953843,"threshold_uncertainty_score":0.99806416},"labels":[],"label_agreement":null},{"id":"W2123201235","doi":"10.1016/j.biopsych.2014.07.024","title":"Looking Beyond the Role of Glycogen Synthase Kinase-3 Genetic Expression on Electroretinogram Response: What About Lithium?","year":2014,"lang":"en","type":"letter","venue":"Biological Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"Canadian Institutes of Health Research","keywords":"GSK-3; Glycogen synthase; Bipolar disorder; GSK3B; Psychiatry; Medicine; Psychology; Biology; Kinase; Genetics; Mood; Internal medicine; Glycogen","score_opus":0.00906926624433924,"score_gpt":0.2387538297232652,"score_spread":0.22968456347892596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2123201235","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88950896,0.044629753,0.0010003534,0.05929107,0.0030716117,0.0012018173,0.00010515789,0.00008270007,0.0011085621],"genre_scores_gemma":[0.60113335,0.0031758144,0.0041465866,0.3763623,0.012907188,0.00023924425,0.0012296353,0.00019667573,0.00060924323],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99650466,0.00094972923,0.000594869,0.0009576767,0.0003493902,0.00064368173],"domain_scores_gemma":[0.9981172,0.0001885195,0.000478628,0.0010259056,0.00009443461,0.0000953048],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006307572,0.0005592783,0.00050812244,0.00008287896,0.00022197411,0.00010587468,0.00089547917,0.0019591355,0.00020573576],"category_scores_gemma":[0.00016592341,0.0003390578,0.00051495864,0.00011085398,0.00023553288,0.0000043148,0.00019209918,0.0010883817,0.000024910109],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011662085,0.00009560214,0.00038050406,0.000044590786,0.000088769884,0.000009501212,0.000019277877,0.000013113156,0.867832,0.000096923184,0.12538962,0.0048638955],"study_design_scores_gemma":[0.00033342716,0.0023520703,0.00024737424,0.00029720765,0.00005046396,0.000027339256,0.00009173724,0.000011937927,0.29823342,0.0024007242,0.6954261,0.000528216],"about_ca_topic_score_codex":0.000005107579,"about_ca_topic_score_gemma":9.741683e-7,"teacher_disagreement_score":0.5700365,"about_ca_system_score_codex":0.000021406044,"about_ca_system_score_gemma":0.00011726004,"threshold_uncertainty_score":0.9999061},"labels":[],"label_agreement":null},{"id":"W2124732042","doi":"10.1124/mol.110.068486","title":"Different Effects of the Different Natural CC Chemokine Receptor 2b Ligands on β-Arrestin Recruitment, Gαi Signaling, and Receptor Internalization","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Arrestin; CCR2; Agonist; Internalization; G protein-coupled receptor; Receptor; C-C chemokine receptor type 6; Endogenous agonist; Biology; Cell biology; Chemokine receptor; Chemistry; Chemokine; Pharmacology; Biochemistry; Dopamine receptor D1","score_opus":0.006969557832211784,"score_gpt":0.2585647412881634,"score_spread":0.25159518345595167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124732042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99292696,0.00052095327,0.0017544333,0.00037604722,0.0035788098,0.00077289017,0.000010955313,0.00001873912,0.000040221683],"genre_scores_gemma":[0.9978201,0.00016143826,0.0002263455,0.00093220297,0.00036988655,0.00013257547,0.000082380495,0.00004721139,0.00022786444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984635,0.00018652466,0.00032467087,0.00049128203,0.00021574408,0.00031826287],"domain_scores_gemma":[0.9991893,0.000057311627,0.00023814439,0.00030265137,0.00009015942,0.00012243445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015305144,0.0003277729,0.00030661546,0.000066029526,0.00010576616,0.000024152989,0.0003392591,0.00024389735,0.00020828398],"category_scores_gemma":[0.00012087437,0.00022890233,0.0001728154,0.000089422654,0.00013485021,0.0000043936084,0.00024331633,0.00040304303,0.0000037108757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019492245,0.00037289844,0.0005789382,0.00006731394,0.00014558302,0.0000031081695,0.00006213127,0.000007949023,0.99546456,0.0002719041,0.00095387787,0.0018768334],"study_design_scores_gemma":[0.002644549,0.0005176249,0.00029797503,0.000057826706,0.000084582214,0.000006344978,0.000007552289,0.00015454055,0.9896956,0.00008908236,0.0062050545,0.00023928186],"about_ca_topic_score_codex":0.000005214165,"about_ca_topic_score_gemma":0.000004915001,"teacher_disagreement_score":0.0057689543,"about_ca_system_score_codex":0.000022585697,"about_ca_system_score_gemma":0.00002647136,"threshold_uncertainty_score":0.9334366},"labels":[],"label_agreement":null},{"id":"W2124874841","doi":"10.1038/sj.emboj.7600387","title":"Receptor activity‐independent recruitment of βarrestin2 reveals specific signalling modes","year":2004,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":117,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Kidney Foundation of Canada; Ariad Pharmaceuticals","keywords":"Biology; Receptor; Library science; Computer science; Biochemistry","score_opus":0.04851136791761845,"score_gpt":0.2803217556767147,"score_spread":0.23181038775909624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124874841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96268743,0.0012674017,0.034712266,0.00029891456,0.00036662366,0.00021551696,0.000005480783,0.000006187765,0.00044017646],"genre_scores_gemma":[0.9943297,0.0010215362,0.003564458,0.000058772275,0.00075401744,0.000010161955,0.000004612335,0.000023915136,0.00023280933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880725,0.00012474302,0.00030873177,0.00019568867,0.00030155288,0.00026205796],"domain_scores_gemma":[0.99925643,0.000019551813,0.00027444286,0.00023738506,0.000110376575,0.00010182979],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008899156,0.00015506722,0.0001866754,0.000041668263,0.00021116056,0.00005023591,0.00032797738,0.00008698331,0.0001863891],"category_scores_gemma":[0.00003700281,0.00010685914,0.00017117521,0.00007012714,0.00005172032,0.0000074065915,0.00007520858,0.00026377005,0.000012653451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011944041,0.00006373998,0.000025975956,0.000006172216,0.000063942265,0.000004603173,0.00012193003,0.006514983,0.9879164,0.00065130513,0.00025363566,0.0042578545],"study_design_scores_gemma":[0.00055285025,0.00030451288,0.00006065535,0.00008613831,0.000017534703,0.00011867351,0.00024873277,0.000023232293,0.99180216,0.0036364838,0.0030082494,0.0001408093],"about_ca_topic_score_codex":0.0000069477674,"about_ca_topic_score_gemma":0.0000019787126,"teacher_disagreement_score":0.031642284,"about_ca_system_score_codex":0.000047753194,"about_ca_system_score_gemma":0.00009338837,"threshold_uncertainty_score":0.43575892},"labels":[],"label_agreement":null},{"id":"W2125318280","doi":"10.1101/lm.037101.114","title":"Epac activation initiates associative odor preference memories in the rat pup","year":2015,"lang":"en","type":"article","venue":"Learning & Memory","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"CREB; Odor; MAPK/ERK pathway; Chemistry; Phosphorylation; Associative learning; Agonist; Neuroscience; Protein kinase A; Psychology; Internal medicine; Endocrinology; Receptor; Biology; Biochemistry; Transcription factor; Medicine","score_opus":0.047458547688597856,"score_gpt":0.26974168890367406,"score_spread":0.2222831412150762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125318280","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950965,0.0002114665,0.0010578859,0.00023952899,0.00017316134,0.00013182993,0.000001086783,0.000014735191,0.0030738183],"genre_scores_gemma":[0.99817723,0.000039352457,0.00032816487,0.00025178483,0.00022460468,0.000026468855,0.000069243804,0.000013291446,0.00086988474],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989742,0.0003310526,0.00013282965,0.0002015017,0.00018077558,0.00017965326],"domain_scores_gemma":[0.9995856,0.00005888807,0.00010512722,0.00013010089,0.00008355775,0.00003672715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072712766,0.0001088801,0.000108597305,0.00003011992,0.00009285718,0.00004588903,0.00015846215,0.00010051776,0.000034052013],"category_scores_gemma":[0.0007946364,0.00008258213,0.000038904975,0.00010088231,0.000031039795,0.000011147584,0.000051302,0.00022613422,0.000013963297],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009032837,0.000049146394,0.0050119166,0.000012090445,0.000032296266,0.000003980753,0.0073411395,0.0016288612,0.9793616,0.00017389315,0.0012048603,0.005089915],"study_design_scores_gemma":[0.0006225162,0.0003185706,0.0026985102,0.000040202332,0.0000120479845,0.0000040028885,0.011242615,0.00020113101,0.97719526,0.0007217327,0.006715933,0.00022747995],"about_ca_topic_score_codex":0.00003150012,"about_ca_topic_score_gemma":0.000019433674,"teacher_disagreement_score":0.0055110725,"about_ca_system_score_codex":0.000025861345,"about_ca_system_score_gemma":0.000066264176,"threshold_uncertainty_score":0.3367602},"labels":[],"label_agreement":null},{"id":"W2125365369","doi":"10.1189/jlb.0908551","title":"An arrestin-dependent multi-kinase signaling complex mediates MIP-1β/CCL4 signaling and chemotaxis of primary human macrophages","year":2009,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Cancer Institute; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Chemotaxis; Biology; Cell biology; Signal transduction; Arrestin; Kinase; Signaling proteins; Immunology; Receptor; Biochemistry; G protein-coupled receptor","score_opus":0.026642210948554918,"score_gpt":0.29533652888760964,"score_spread":0.26869431793905474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125365369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904732,0.0044419835,0.0046621608,0.00006637854,0.00017957314,0.00011680709,0.000014956582,0.000008324847,0.000036608864],"genre_scores_gemma":[0.984043,0.00040869068,0.01460388,0.00025560072,0.0005835826,0.0000013472552,0.000059062833,0.000023115608,0.000021693015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981016,0.00022195095,0.0008241218,0.00033691234,0.00017764475,0.0003377567],"domain_scores_gemma":[0.99847364,0.00004985404,0.00076636573,0.00022639494,0.0002746788,0.00020904512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00081006536,0.00027021926,0.00058916514,0.0001489996,0.00013084186,0.000030995274,0.00035642626,0.00027669614,0.000074665586],"category_scores_gemma":[0.00009242077,0.00022792058,0.00017765467,0.00007214688,0.00014748717,0.000016679134,0.00006635768,0.0002430435,8.289966e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021999536,0.00015331707,0.0015918047,0.000030906096,0.000087273205,0.000033397533,0.00010358963,0.00024261237,0.9919698,0.000047447127,0.000028280958,0.0054915366],"study_design_scores_gemma":[0.001653113,0.0026690124,0.003275827,0.000055419685,0.000057541536,0.00014743234,0.00015712397,0.000112582464,0.99088943,0.00031974158,0.0004109029,0.00025184374],"about_ca_topic_score_codex":0.000019143486,"about_ca_topic_score_gemma":0.000004710608,"teacher_disagreement_score":0.0099417195,"about_ca_system_score_codex":0.00003612918,"about_ca_system_score_gemma":0.000106915875,"threshold_uncertainty_score":0.9294331},"labels":[],"label_agreement":null},{"id":"W2125514019","doi":"10.1016/j.pupt.2012.06.005","title":"Regulation of GPCR-mediated smooth muscle contraction: Implications for asthma and pulmonary hypertension","year":2012,"lang":"en","type":"review","venue":"Pulmonary Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; University of Manitoba; Research Manitoba","funders":"","keywords":"G protein-coupled receptor; Contraction (grammar); Smooth muscle; Muscle contraction; Receptor; Sensitization; Medicine; Pulmonary hypertension; Cell biology; Biology; Anatomy; Endocrinology; Internal medicine; Immunology","score_opus":0.06925680505595985,"score_gpt":0.3342278462974125,"score_spread":0.26497104124145265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125514019","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009786739,0.99559706,0.0010336894,0.0001649167,0.00066751166,0.0012232381,0.00024099275,0.000022228038,0.00007169784],"genre_scores_gemma":[0.016532166,0.9795056,0.00050145685,0.0003969422,0.00075058546,0.0003249531,0.0017798862,0.00008920192,0.00011923787],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99830604,0.00019921288,0.0005742761,0.00048157174,0.00008685174,0.00035207754],"domain_scores_gemma":[0.9987226,0.0001726922,0.0005146996,0.00028619476,0.00019043453,0.00011337274],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003153718,0.00037884328,0.0007506879,0.00010973848,0.00016360283,0.000010512785,0.00020003169,0.00065619143,0.00007392364],"category_scores_gemma":[0.000004956291,0.00034331242,0.00029714065,0.00012762364,0.00012262324,0.000012127112,0.00008721523,0.00020845568,0.000004035914],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004223993,0.00014809125,0.000009400943,0.0006167254,0.00016885983,6.547557e-7,0.0000043385708,0.0000020874143,0.42707065,0.000018217459,0.00007416425,0.5718446],"study_design_scores_gemma":[0.00025862767,0.00013688192,0.0003256495,0.00014072862,0.0017399522,0.00011301515,0.000011883743,0.00017707492,0.0030794116,0.000091519556,0.99360174,0.00032353634],"about_ca_topic_score_codex":0.000003307896,"about_ca_topic_score_gemma":7.136115e-7,"teacher_disagreement_score":0.99352753,"about_ca_system_score_codex":0.000029810562,"about_ca_system_score_gemma":0.00012222108,"threshold_uncertainty_score":0.9999019},"labels":[],"label_agreement":null},{"id":"W2125616763","doi":"10.1371/journal.pone.0029420","title":"Impedance Responses Reveal β2-Adrenergic Receptor Signaling Pluridimensionality and Allow Classification of Ligands with Distinct Signaling Profiles","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"G protein-coupled receptor; Signal transduction; Receptor; Drug discovery; Agonist; Biology; Cell biology; Bioinformatics; Biochemistry","score_opus":0.03590122430391236,"score_gpt":0.2390170245177418,"score_spread":0.2031158002138294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125616763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99745417,0.001505277,0.00060163985,0.00006860785,0.000035368746,0.00022177986,0.000036592937,0.000018108396,0.000058441714],"genre_scores_gemma":[0.98727417,0.00009084492,0.011792794,0.000037407914,0.0003060598,0.00004067968,0.00013488533,0.000031795524,0.00029136176],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998653,0.0001055497,0.0003174741,0.0003344365,0.00030399585,0.0002855579],"domain_scores_gemma":[0.9991288,0.000068102076,0.00023145071,0.0002494608,0.00018853848,0.00013362839],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006196901,0.00018965986,0.00027259323,0.00004384186,0.00011877094,0.000018197055,0.00010404454,0.00013703614,0.000053953354],"category_scores_gemma":[0.0001565075,0.00015944912,0.00005137446,0.000096677984,0.00009187089,0.000015821297,0.00006158194,0.00010117143,0.0000025160864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051738287,0.0003289112,0.017276771,0.000115728486,0.00013975702,3.9648506e-7,0.00011134847,0.000010191161,0.98110884,0.00021224825,0.00002493182,0.00015347709],"study_design_scores_gemma":[0.0003611731,0.0003544227,0.003934439,0.00024018368,0.000090808826,0.0000033983254,0.00010717819,0.0000928354,0.9944772,0.000037616705,0.000078546065,0.00022220338],"about_ca_topic_score_codex":0.0000092711825,"about_ca_topic_score_gemma":0.0000021821065,"teacher_disagreement_score":0.013368338,"about_ca_system_score_codex":0.000014496834,"about_ca_system_score_gemma":0.00007209341,"threshold_uncertainty_score":0.6502146},"labels":[],"label_agreement":null},{"id":"W2125943096","doi":"10.1007/978-0-387-73657-0_147","title":"Photoprobe Peptides to Map the Interactions of Angiotensin II with its Receptor AT1","year":2009,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Angiotensin II receptor type 1; Angiotensin II; Chemistry; Receptor; Computational biology; Biochemistry; Biology","score_opus":0.016542972186505828,"score_gpt":0.3254640886488008,"score_spread":0.3089211164622949,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125943096","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9813078,0.01599621,0.00030772956,0.0015054062,0.00020418111,0.00019874205,0.0000031317588,0.000004205571,0.00047259155],"genre_scores_gemma":[0.99646,0.0006904908,0.001572774,0.0009479267,0.00017224363,0.000015823685,0.000021537791,0.0000049247005,0.0001142593],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99943453,0.000030256388,0.00015690252,0.00020693472,0.000038311828,0.00013303464],"domain_scores_gemma":[0.99975294,0.000015014045,0.00005348251,0.00010878763,0.000030426076,0.000039336126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008066465,0.00010300938,0.0001525868,0.000039237948,0.00005884008,0.0000018141465,0.00008399274,0.000043635857,0.00005680176],"category_scores_gemma":[0.000018415443,0.000057480083,0.000019484434,0.00007078191,0.00011116686,0.0000067403253,0.000042520714,0.000054956156,9.2884767e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016491833,0.000041862397,0.00014405053,0.0000022714873,0.000007717708,5.254222e-7,0.00041848858,0.000008212273,0.9925258,0.0004919098,0.0002656014,0.005928631],"study_design_scores_gemma":[0.00038879912,0.0037487014,0.000054952365,0.00006056967,0.0000038209105,0.000017233322,0.0015159193,0.0000070178594,0.9259668,0.000101640035,0.068053976,0.000080593054],"about_ca_topic_score_codex":0.00001683441,"about_ca_topic_score_gemma":0.000025185167,"teacher_disagreement_score":0.06778838,"about_ca_system_score_codex":0.000006815887,"about_ca_system_score_gemma":0.000007858158,"threshold_uncertainty_score":0.23439698},"labels":[],"label_agreement":null},{"id":"W2126541892","doi":"10.1016/s0024-3205(01)01012-8","title":"Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells","year":2001,"lang":"en","type":"article","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"G protein-coupled receptor; Receptor; HEK 293 cells; Cell biology; Agonist; Chemistry; Biology; Biophysics; Biochemistry","score_opus":0.011928247018037255,"score_gpt":0.2440828865662129,"score_spread":0.23215463954817567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126541892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977004,0.00017765992,0.0015893212,0.00007908051,0.00004932617,0.000040974854,0.0000013120068,0.0000019919012,0.00035995682],"genre_scores_gemma":[0.998546,0.00015016057,0.0011695998,0.00004787462,0.00005625011,0.0000017349665,0.0000055497167,0.000002006117,0.000020825339],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99955046,0.000017513936,0.00010673864,0.00015622166,0.000080397374,0.000088653454],"domain_scores_gemma":[0.99986434,0.0000047730605,0.000035627196,0.000045707766,0.000013509518,0.000036020774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012055846,0.000044783978,0.000058437323,0.000032226235,0.000030565796,0.000009626358,0.000064697895,0.000048214482,0.000014519767],"category_scores_gemma":[0.000017981094,0.000038791608,0.000015308531,0.00014919543,0.00012921184,0.0000050094145,0.000015902911,0.000019325033,8.130319e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000064902547,0.0000150765945,0.0032390119,0.0000031899788,9.700425e-7,2.1488009e-7,0.000019697032,0.000048329144,0.9957539,0.00038919045,0.000021357017,0.00050260354],"study_design_scores_gemma":[0.00008725441,0.000106727704,0.0013935243,0.0000062424915,0.0000015141738,0.0000015330967,0.00009702176,0.0006150188,0.9973169,0.00011366788,0.00020949866,0.00005107097],"about_ca_topic_score_codex":0.000023211713,"about_ca_topic_score_gemma":0.0000046191303,"teacher_disagreement_score":0.0018454875,"about_ca_system_score_codex":0.0000014386607,"about_ca_system_score_gemma":0.00002865533,"threshold_uncertainty_score":0.15818758},"labels":[],"label_agreement":null},{"id":"W2127148939","doi":"10.1124/jpet.109.156398","title":"Functional Selectivity of Natural and Synthetic Prostaglandin EP4 Receptor Ligands","year":2009,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Receptor; Ligand (biochemistry); G protein-coupled receptor; Selectivity; Stereochemistry; G protein; Biochemistry","score_opus":0.01286929269770961,"score_gpt":0.29160247428253244,"score_spread":0.27873318158482285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127148939","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890724,0.009953517,0.00020267797,0.00024437904,0.00042952292,0.00006469367,0.0000025538645,0.000001918563,0.000028338296],"genre_scores_gemma":[0.99794614,0.000782186,0.00037771664,0.000577008,0.00024182045,0.0000011547329,0.0000029752778,0.000006181801,0.000064840024],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944794,0.000045177665,0.00020211803,0.00010815741,0.00008464806,0.00011196168],"domain_scores_gemma":[0.99968475,0.000015628983,0.0001587389,0.000032644573,0.000063047795,0.000045163444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019247753,0.00010082555,0.00016383795,0.00004167083,0.00006382987,0.000008630108,0.000050241753,0.00008752626,0.00006441503],"category_scores_gemma":[0.0000036062675,0.000080908874,0.000054983913,0.00003484003,0.000078472905,0.000009322843,0.000020301673,0.00012882204,2.3864658e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008908551,0.0001519431,0.00025213612,0.0000046929713,0.000118278214,0.0000015519697,0.00014609148,0.000007285369,0.9958735,0.000054526343,0.00036649228,0.0021326365],"study_design_scores_gemma":[0.001176317,0.0017047868,0.0003562936,0.000007930928,0.000042673928,0.00014293003,0.0001376681,0.0000631545,0.9942403,0.000095604555,0.0019476804,0.000084684776],"about_ca_topic_score_codex":3.8621044e-7,"about_ca_topic_score_gemma":9.163795e-8,"teacher_disagreement_score":0.00917133,"about_ca_system_score_codex":0.000011863979,"about_ca_system_score_gemma":0.00003806235,"threshold_uncertainty_score":0.3299368},"labels":[],"label_agreement":null},{"id":"W2127395827","doi":"10.1016/j.ydbio.2007.04.049","title":"Neural induction in the absence of organizer in salamanders is mediated by MAPK","year":2007,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Heart and Stroke Foundation of Canada; Howard Hughes Medical Institute","keywords":"Biology; Ectoderm; MAPK/ERK pathway; Cell biology; Neural development; Gastrulation; Neural plate; Inducer; Anatomy; Embryo; Neural crest; Embryogenesis; Genetics; Signal transduction","score_opus":0.009677851578473968,"score_gpt":0.23930249237984544,"score_spread":0.22962464080137146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127395827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991313,0.00015507701,0.00022085058,0.00009336325,0.0001155006,0.00009586883,0.000005711238,0.0000024417004,0.00017986659],"genre_scores_gemma":[0.9987842,0.000056804154,0.0003331529,0.0005624774,0.00002060026,0.000004117145,0.00020793478,0.000005895243,0.00002485905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999318,0.000045505752,0.00022366899,0.00017905826,0.000052578875,0.00018117939],"domain_scores_gemma":[0.9998316,0.000018282959,0.00005166376,0.00006372075,0.000016708753,0.0000180246],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037938816,0.00008283869,0.00009319658,0.000054315115,0.00001973828,0.000003011466,0.00013328237,0.00015020375,0.00007012213],"category_scores_gemma":[0.000032334054,0.000062244435,0.000017801305,0.00016498248,0.00005346633,0.0000025369422,0.00003877988,0.00008281541,0.0000053831113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029067201,0.000024001007,0.046483833,0.0000022077245,0.0000058732476,0.0000015492749,0.00039249807,4.7673493e-7,0.9517272,0.000022429169,0.00036924792,0.0009415845],"study_design_scores_gemma":[0.00038354195,0.00008474793,0.029665941,0.0000043481095,7.6652503e-7,0.000013488401,0.0013533311,0.0000052026962,0.96638966,0.000063041945,0.0019368066,0.0000991429],"about_ca_topic_score_codex":0.00006503811,"about_ca_topic_score_gemma":0.00015878904,"teacher_disagreement_score":0.016817894,"about_ca_system_score_codex":0.000018489403,"about_ca_system_score_gemma":0.000028251958,"threshold_uncertainty_score":0.25382543},"labels":[],"label_agreement":null},{"id":"W2128304515","doi":"10.1161/01.res.0000043282.39776.7c","title":"Gα <sub>12/13</sub> Mediates α <sub>1</sub> -Adrenergic Receptor–Induced Cardiac Hypertrophy","year":2002,"lang":"en","type":"article","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Amgen (Canada); University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Pertussis toxin; G protein; Protein kinase A; Cell biology; Heterotrimeric G protein; GTP-binding protein regulators; Kinase; Gq alpha subunit; Gs alpha subunit; Biology; Receptor; Protein subunit; Molecular biology; G alpha subunit; Signal transduction; Biochemistry","score_opus":0.05476263559659067,"score_gpt":0.2829803910912199,"score_spread":0.22821775549462925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128304515","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948063,0.0018800589,0.00030683092,0.00020295322,0.0006094308,0.00046559647,0.00002282079,0.000051731688,0.0016542703],"genre_scores_gemma":[0.9962493,0.0016406819,0.00008589501,0.00008482659,0.0012608862,0.0001216229,0.00034995814,0.00008642219,0.00012040847],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99634635,0.0005421396,0.00044330402,0.0008600951,0.00096261385,0.00084548624],"domain_scores_gemma":[0.9982484,0.00009694134,0.00011237157,0.00069807336,0.0005104986,0.00033369262],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010994318,0.0003077807,0.00033330976,0.00027955178,0.00046879373,0.00015781226,0.0003730637,0.00049284,0.00030126746],"category_scores_gemma":[0.0003724043,0.00031304185,0.00027808742,0.0004971809,0.00013333144,0.00002386284,0.00019198694,0.00045521007,0.0004406315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038409737,0.00007807142,0.00092119013,0.000025892388,0.00007813152,0.000005205782,0.00010203238,0.0008481545,0.9752583,0.0001001323,0.0029645977,0.019579865],"study_design_scores_gemma":[0.0004901448,0.0002528773,0.0020561246,0.000028070575,0.00001693022,0.000005108706,0.000099271514,0.0022716417,0.9915086,0.00020819563,0.0026877816,0.0003752743],"about_ca_topic_score_codex":0.000039460432,"about_ca_topic_score_gemma":0.000018561057,"teacher_disagreement_score":0.01920459,"about_ca_system_score_codex":0.00009359758,"about_ca_system_score_gemma":0.0001018019,"threshold_uncertainty_score":0.99993217},"labels":[],"label_agreement":null},{"id":"W2128670872","doi":"10.1124/mol.110.063859","title":"The Angiotensin II Type 1 Receptor Induces Membrane Blebbing by Coupling to Rho A, Rho Kinase, and Myosin Light Chain Kinase","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"RHOA; Myosin light-chain kinase; Angiotensin II; Cell biology; Rho-associated protein kinase; Kinase; Biology; Myosin; Chemistry; Signal transduction; Receptor; Biochemistry","score_opus":0.005582679800888398,"score_gpt":0.24745049505536265,"score_spread":0.24186781525447426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128670872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99102753,0.0026273825,0.0005357969,0.0035128477,0.0016952064,0.00042252496,0.00001487868,0.00002435897,0.00013945518],"genre_scores_gemma":[0.99479914,0.0003606558,0.0014724705,0.0021289007,0.00045341218,0.00004608679,0.00007017098,0.000063344065,0.0006058033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982438,0.00010339926,0.00029793702,0.00061927934,0.0001737687,0.0005618193],"domain_scores_gemma":[0.9990996,0.00003691712,0.00011124121,0.00031604894,0.00016746573,0.00026871797],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057101273,0.00030273266,0.00025050668,0.0000697524,0.0005325769,0.00007300302,0.00033638437,0.00032854135,0.00024644713],"category_scores_gemma":[0.00009953836,0.0002567971,0.00009046438,0.00020432622,0.00010882738,0.0000071481068,0.00032402793,0.00037680328,0.000022213118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014115078,0.000053922977,0.000010515509,0.0000066244897,0.00010522557,0.000017826516,0.00009621209,0.000086722146,0.98483115,0.00009405497,0.0120084835,0.0025480865],"study_design_scores_gemma":[0.00047223567,0.00031611952,0.0000038658027,0.000007129279,0.000042269647,0.000014797618,0.000045527428,0.00027277874,0.769448,0.000018314491,0.22910501,0.0002539745],"about_ca_topic_score_codex":0.000027937904,"about_ca_topic_score_gemma":0.00001979003,"teacher_disagreement_score":0.21709652,"about_ca_system_score_codex":0.000015824913,"about_ca_system_score_gemma":0.00007912107,"threshold_uncertainty_score":0.99998844},"labels":[],"label_agreement":null},{"id":"W2128768874","doi":"10.1093/nar/gkn728","title":"IUPHAR-DB: the IUPHAR database of G protein-coupled receptors and ion channels","year":2008,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":220,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"Servier; University of Oxford; British Pharmacological Society; Incyte; GlaxoSmithKline","keywords":"Biology; G protein-coupled receptor; Clinical pharmacology; Gene; Receptor; Systems pharmacology; Drug discovery; Computational biology; Pharmacology; Drug; Bioinformatics; Genetics","score_opus":0.047720668756415334,"score_gpt":0.3184688695125029,"score_spread":0.2707482007560876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128768874","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966216,0.0013543199,0.0006375034,0.00024597673,0.00014596304,0.00055140053,0.000017712264,0.000009873985,0.00041565357],"genre_scores_gemma":[0.9956773,0.0013040769,0.0007626021,0.000040247047,0.00038519787,0.00006633504,0.000055821598,0.000033119406,0.0016753194],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99822074,0.00023311411,0.00022869818,0.0003978907,0.00050576957,0.00041379145],"domain_scores_gemma":[0.9990312,0.00003625808,0.000060651942,0.0004905302,0.00025485354,0.00012654353],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012430034,0.00014138699,0.00016673346,0.00008424441,0.0003797895,0.000027855263,0.00037991593,0.0001479629,0.00038777132],"category_scores_gemma":[0.00019537643,0.000101821126,0.00006597234,0.0002343653,0.0003775031,0.000010283032,0.00035337935,0.00028702064,0.00002037922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014370402,0.0000508866,0.00019429708,0.000035546167,0.000030241388,0.0000059193417,0.00020927744,0.0000060403822,0.99567395,0.00031035274,0.0020097387,0.00133002],"study_design_scores_gemma":[0.0004969507,0.00045030587,0.00010722747,0.00004112812,0.000004570947,0.000024356543,0.0002669508,0.00039556075,0.9603295,0.00012038879,0.03762874,0.00013433762],"about_ca_topic_score_codex":0.00008506359,"about_ca_topic_score_gemma":0.0000043619043,"teacher_disagreement_score":0.035619,"about_ca_system_score_codex":0.000014169848,"about_ca_system_score_gemma":0.00010667223,"threshold_uncertainty_score":0.4245824},"labels":[],"label_agreement":null},{"id":"W2128864168","doi":"10.1016/j.yjmcc.2013.05.003","title":"Regulation of cardiac nitric oxide signaling by nuclear β-adrenergic and endothelin receptors","year":2013,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; McGill University; Montreal Heart Institute; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Agonist; Nitric oxide; Intracellular; Endothelin receptor; Internal medicine; Endothelin 1; Chemistry; Nitric oxide synthase; Endocrinology; Signal transduction; Cell biology; Biology; Biochemistry; Medicine","score_opus":0.00370938822475428,"score_gpt":0.17736264778654431,"score_spread":0.17365325956179004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128864168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98343766,0.013249543,0.0029601064,0.000026509973,0.00010184396,0.00010046,0.0000033719148,0.000001772669,0.00011875446],"genre_scores_gemma":[0.9973585,0.001274209,0.0011525501,0.000045561763,0.00009214476,0.0000024632295,0.000012150899,0.000021470967,0.000040959458],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988545,0.00023353194,0.00042271757,0.00018924449,0.00012514359,0.00017487264],"domain_scores_gemma":[0.99940246,0.00001864075,0.00024285834,0.00012362166,0.00012273875,0.000089698944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004474369,0.0001385257,0.00040810692,0.00011258831,0.000029786195,0.000014765737,0.00009156067,0.00019898165,0.000030320267],"category_scores_gemma":[0.000047312995,0.00012456217,0.00017453801,0.00006961206,0.00007232632,0.000009486322,0.000049917868,0.00013015186,8.1764125e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037027818,0.000009976079,0.0011097223,0.000015024331,0.000102450336,0.000006172557,0.000023086679,0.0003409722,0.99635834,0.00008886564,0.0001655488,0.0017427905],"study_design_scores_gemma":[0.00043621566,0.0002611322,0.000519662,0.000021683394,0.00005248261,0.000073969284,0.00021813456,0.00005843028,0.99558425,0.00041552007,0.0022197107,0.00013879173],"about_ca_topic_score_codex":0.000024071074,"about_ca_topic_score_gemma":1.5200828e-7,"teacher_disagreement_score":0.013920852,"about_ca_system_score_codex":0.000009434829,"about_ca_system_score_gemma":0.000024094776,"threshold_uncertainty_score":0.50794977},"labels":[],"label_agreement":null},{"id":"W2128936019","doi":"10.1111/j.1440-1681.2008.05064.x","title":"DOPAMINE D2 RECEPTOR STIMULATION INHIBITS ANGIOTENSIN II‐INDUCED HYPERTROPHY IN CULTURED NEONATAL RAT VENTRICULAR MYOCYTES","year":2008,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University","funders":"National Natural Science Foundation of China","keywords":"Internal medicine; Endocrinology; Angiotensin II; Muscle hypertrophy; Bromocriptine; Protein kinase C; Receptor; Protein kinase A; Myocyte; Biology; Chemistry; Kinase; Medicine; Cell biology; Prolactin; Hormone","score_opus":0.02419137140194514,"score_gpt":0.31430137473139547,"score_spread":0.2901100033294503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2128936019","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99450827,0.004368266,0.000024050101,0.00014639745,0.0007063139,0.00021528354,0.0000056262425,0.000011482378,0.000014337192],"genre_scores_gemma":[0.9970988,0.000743491,0.00034507414,0.00091144646,0.00063423155,0.000023742028,0.00015353545,0.000013838931,0.00007585994],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986095,0.00020969476,0.00036006758,0.00051012693,0.000053926404,0.0002566948],"domain_scores_gemma":[0.9996206,0.0000433877,0.0000828181,0.00008923584,0.000034660396,0.00012927268],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013089576,0.00020081972,0.00033817848,0.000039318256,0.00021777373,0.000004832095,0.00007384238,0.0003324675,0.00012904931],"category_scores_gemma":[0.000025508514,0.00017081542,0.00009089694,0.000067761626,0.0003093944,0.000011708416,0.00018546627,0.00020018913,0.0000059920794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008680094,0.00024526718,0.0014049158,0.000004369584,0.000046671328,0.000021296008,0.00011233794,0.000034500677,0.9955956,0.000019319563,0.0009063775,0.0007413718],"study_design_scores_gemma":[0.0031704698,0.0015351329,0.0028604323,0.000006255367,0.000015686794,0.0000699929,0.00006915468,0.00028268335,0.98712915,0.000060278533,0.0045735403,0.00022723348],"about_ca_topic_score_codex":0.000011377064,"about_ca_topic_score_gemma":0.0000011091375,"teacher_disagreement_score":0.0084664235,"about_ca_system_score_codex":0.000007761404,"about_ca_system_score_gemma":0.000022234173,"threshold_uncertainty_score":0.69656503},"labels":[],"label_agreement":null},{"id":"W2129463886","doi":"10.1210/endo.141.12.7834","title":"Localization of G Protein α-Subunits in the Human Fetal Adrenal Gland<sup>1</sup>","year":2000,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Medical Research Council; Medical Research Council Canada; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; Université de Sherbrooke","keywords":"Fetus; Adrenal gland; Endocrinology; Alpha (finance); Internal medicine; Biology; G alpha subunit; Heterotrimeric G protein; Protein subunit; Cell type; G protein; Cell; Signal transduction; Cell biology; Pregnancy; Medicine; Biochemistry","score_opus":0.01097691394387768,"score_gpt":0.24141783227651348,"score_spread":0.2304409183326358,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129463886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99604213,0.00029572225,0.0010434539,0.00007620101,0.000020082069,0.00020377709,0.0000055588407,0.00000663472,0.0023064425],"genre_scores_gemma":[0.9989123,0.000049514914,0.0001340958,0.00013118309,0.00011838349,0.00003231148,0.00010151608,0.0000105196905,0.00051019806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991197,0.0001507489,0.00020865345,0.00019565811,0.00008860854,0.00023665435],"domain_scores_gemma":[0.99969184,0.000006991642,0.00004398254,0.00020805564,0.000028531696,0.000020592059],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000101343045,0.000101985104,0.00012384284,0.000042760068,0.00006133413,0.000007611206,0.00020514973,0.00009043948,0.00062664115],"category_scores_gemma":[0.000017831837,0.00007849738,0.000049198785,0.00009117009,0.00006757598,0.0000028698105,0.00002963707,0.000100667756,0.000012385663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021037596,0.00033023345,0.004840399,0.000047193236,0.00008235757,0.00005845078,0.0011143889,0.009355392,0.92954355,0.0064735394,0.00066402956,0.04728007],"study_design_scores_gemma":[0.0018532354,0.0009684634,0.00082696805,0.00003302485,0.000018326225,0.00014624199,0.00048884534,0.0015493243,0.91341096,0.0013051385,0.07910342,0.00029607423],"about_ca_topic_score_codex":0.00008414243,"about_ca_topic_score_gemma":0.00003625261,"teacher_disagreement_score":0.078439385,"about_ca_system_score_codex":0.00000519211,"about_ca_system_score_gemma":0.00002183187,"threshold_uncertainty_score":0.68612814},"labels":[],"label_agreement":null},{"id":"W2129920953","doi":"10.1139/cjpp-2014-0507","title":"Profiling of cardiac β-adrenoceptor subtypes in the cardiac left ventricle of rats with metabolic syndrome: Comparison with streptozotocin-induced diabetic rats","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Türkiye Bilimsel ve Teknolojik Araştırma Kurumu","keywords":"Internal medicine; Streptozotocin; Endocrinology; Diabetic cardiomyopathy; Cardiac function curve; Medicine; Ventricle; Agonist; Diabetes mellitus; Cardiomyopathy; Receptor; Heart failure","score_opus":0.01565273955286675,"score_gpt":0.2572119464940241,"score_spread":0.24155920694115737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129920953","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947475,0.0045626643,0.000013082815,0.00006489329,0.00031988957,0.0002446094,0.00002282301,8.3597814e-7,0.000023665081],"genre_scores_gemma":[0.99948716,0.00009057186,0.00018354328,0.000067554516,0.00012866792,0.0000074010763,0.000017013732,0.000012343111,0.0000057467855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987349,0.00041014704,0.0003246847,0.0001661612,0.00009707783,0.0002670181],"domain_scores_gemma":[0.99908876,0.00004851676,0.000318886,0.000116465875,0.00022421301,0.00020314746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005021782,0.00014517742,0.00054945727,0.00011972599,0.000050129285,0.0000053684153,0.00019789442,0.00012451239,0.00006653884],"category_scores_gemma":[0.000018654491,0.00009645078,0.00007350753,0.00013120199,0.00019501906,0.000009930326,0.000015558684,0.00022189555,3.3621106e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025563085,0.00003370257,0.03283076,0.000034145425,0.0002689822,0.00001358596,0.0004996529,0.0003751526,0.96529377,0.000035020534,0.00018758648,0.00017200859],"study_design_scores_gemma":[0.00065395393,0.0017584303,0.008970342,0.000020315234,0.00015778765,0.000041890522,0.0006661603,0.000015428497,0.98701215,0.00004160046,0.00055078353,0.00011113602],"about_ca_topic_score_codex":0.00023453416,"about_ca_topic_score_gemma":0.00020173963,"teacher_disagreement_score":0.02386042,"about_ca_system_score_codex":0.000014075364,"about_ca_system_score_gemma":0.0007729312,"threshold_uncertainty_score":0.39331487},"labels":[],"label_agreement":null},{"id":"W2129987233","doi":"10.1073/pnas.1112422109","title":"Engagement of β-arrestin by transactivated insulin-like growth factor receptor is needed for V2 vasopressin receptor-stimulated ERK1/2 activation","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Centre National de la Recherche Scientifique; Kidney Foundation of Canada","keywords":"Insulin-like growth factor 1 receptor; Cell biology; G protein-coupled receptor; Transactivation; Biology; Receptor; Growth factor receptor; Proto-oncogene tyrosine-protein kinase Src; Insulin-like growth factor; Tyrosine kinase; Growth factor; Arrestin; Chemistry; Internal medicine; Signal transduction; Biochemistry; Transcription factor; Medicine","score_opus":0.04392875683103109,"score_gpt":0.2973099701920613,"score_spread":0.2533812133610302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129987233","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982354,0.00017806777,0.00025613458,0.00062722526,0.000065516215,0.00037025695,0.00011677402,0.000006987269,0.00014365383],"genre_scores_gemma":[0.9951835,0.000054683544,0.0043076025,0.00021428973,0.00010076327,0.000022971071,0.000007703839,0.00001048398,0.00009799431],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998528,0.000017805094,0.0003876498,0.00024872672,0.0006111377,0.00020669191],"domain_scores_gemma":[0.9988819,0.00007729158,0.0005382915,0.000013884436,0.00043575687,0.000052894437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010066342,0.00013802803,0.00017764546,0.00008564795,0.00016018581,0.000014178774,0.00045335555,0.00018355821,0.00008281043],"category_scores_gemma":[0.0004748849,0.000102168786,0.00011003988,0.0003532172,0.00020990179,0.00006518072,0.000053975764,0.00011690687,4.127774e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010488713,0.00009434625,0.0006072752,0.000065419976,0.000044729175,9.8117826e-11,0.00029285904,0.00003126854,0.99436164,0.00045906627,0.0034719731,0.00046653664],"study_design_scores_gemma":[0.00040568682,0.0001314541,0.0008319638,0.0000708132,0.000013307749,2.4167733e-7,0.00019280979,0.0002378921,0.9957267,0.0006039845,0.0016696277,0.00011550051],"about_ca_topic_score_codex":0.000010796101,"about_ca_topic_score_gemma":9.553897e-9,"teacher_disagreement_score":0.0040514683,"about_ca_system_score_codex":0.000023017412,"about_ca_system_score_gemma":0.000037078786,"threshold_uncertainty_score":0.41663224},"labels":[],"label_agreement":null},{"id":"W2130141176","doi":"10.1124/mol.113.087551","title":"Muscarinic Receptors as Model Targets and Antitargets for Structure-Based Ligand Discovery","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Division of Chemistry; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Bayerisch-Kalifornischen Hochschulzentrum; Emory University; National Institutes of Health; National Science Foundation","keywords":"Receptor; G protein-coupled receptor; Muscarinic acetylcholine receptor; Docking (animal); Agonist; Allosteric regulation; Chemistry; Stereochemistry; Muscarinic acetylcholine receptor M2; Muscarinic acetylcholine receptor M3; Drug discovery; Biochemistry","score_opus":0.0064318981385366,"score_gpt":0.25673492907663936,"score_spread":0.25030303093810274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130141176","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9172246,0.0013351901,0.07968146,0.00033647052,0.00055910955,0.0007150626,0.000034272853,0.000018926943,0.0000948965],"genre_scores_gemma":[0.9890988,0.00009246696,0.0072695087,0.002597468,0.00016594569,0.00016242715,0.0001929136,0.0000560207,0.00036448112],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986178,0.00006593407,0.00023283761,0.0005518517,0.00010705281,0.00042446793],"domain_scores_gemma":[0.99943584,0.000019713345,0.00009153919,0.00019028214,0.000111167086,0.00015145213],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011296723,0.00026054063,0.00024047376,0.00006839648,0.00012255709,0.000059184917,0.00018555633,0.00024186951,0.00022911793],"category_scores_gemma":[0.000036782163,0.00024941706,0.00013232288,0.000054431526,0.00008711369,0.000015126348,0.00010315872,0.0001150282,0.0000075382236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009040829,0.000040377727,0.000050992523,0.000031937405,0.00010139248,0.000004608273,0.000020191403,0.0036899499,0.991835,0.00023266967,0.003180785,0.00072166364],"study_design_scores_gemma":[0.0013421911,0.00038101722,0.00001841854,0.000004945589,0.00006253523,0.000009247244,0.000015852389,0.018093523,0.97289175,0.0019373606,0.004941067,0.0003020974],"about_ca_topic_score_codex":0.000021106296,"about_ca_topic_score_gemma":0.0000032062976,"teacher_disagreement_score":0.072411954,"about_ca_system_score_codex":0.00001480467,"about_ca_system_score_gemma":0.000107547654,"threshold_uncertainty_score":0.9999958},"labels":[],"label_agreement":null},{"id":"W2130579948","doi":"10.1016/j.bmcl.2010.11.015","title":"Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases","year":2010,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Antagonist; Chemistry; Pharmacology; Pharmacokinetics; Stereochemistry; Receptor; Biochemistry; Medicine","score_opus":0.00914967195800938,"score_gpt":0.24332913342863416,"score_spread":0.23417946147062477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130579948","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955148,0.0013130839,0.0020811246,0.00042153796,0.0002459154,0.0002556671,0.00012883998,0.0000068358263,0.000032171152],"genre_scores_gemma":[0.9984407,0.00012889036,0.00013011991,0.00025159662,0.0008354662,0.000041763833,0.00006994024,0.000024827841,0.00007673908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902654,0.000016765169,0.0002758324,0.00029800352,0.00017378667,0.00020908167],"domain_scores_gemma":[0.9992127,0.00006996522,0.00019536336,0.0003739553,0.000082453815,0.00006555426],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110596586,0.00018934983,0.00023995257,0.000014780256,0.00008708158,0.000011418626,0.00022684048,0.00011403549,0.00004735909],"category_scores_gemma":[0.00009784538,0.00012821035,0.00019071475,0.00007652245,0.00026724904,0.000004577068,0.000025514188,0.000078765144,4.1066647e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021856038,0.00013552673,0.0008071415,0.00006849054,0.0001526923,0.000001752543,0.00008211388,0.000002086807,0.9970019,0.000011410355,0.00080701127,0.0007112986],"study_design_scores_gemma":[0.00086093793,0.00036008234,0.00057660224,0.000018264442,0.00014452628,0.0000077777795,0.00020261765,0.000009765672,0.9904681,0.000012769152,0.0072067385,0.00013183375],"about_ca_topic_score_codex":0.000023814362,"about_ca_topic_score_gemma":0.0000061148917,"teacher_disagreement_score":0.006533831,"about_ca_system_score_codex":0.000022983644,"about_ca_system_score_gemma":0.00014414667,"threshold_uncertainty_score":0.5228266},"labels":[],"label_agreement":null},{"id":"W2130619870","doi":"10.2174/138955712800959143","title":"Functional Selectivity in GPCR Signaling: Understanding the Full Spectrum of Receptor Conformations","year":2012,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Functional selectivity; Allosteric regulation; Receptor; Ligand (biochemistry); Metabotropic glutamate receptor; Signal transduction; Metabotropic receptor; Chemistry; Rhodopsin-like receptors; Rhodopsin; Biology; Neuroscience; Computational biology; Agonist; Biochemistry","score_opus":0.09623266167367109,"score_gpt":0.31488399433457637,"score_spread":0.21865133266090528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130619870","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004858776,0.9950239,0.0023134507,0.000052846193,0.00034129972,0.0006790033,0.00003280505,0.0000058772284,0.0010649073],"genre_scores_gemma":[0.0052787936,0.99272114,0.00017238104,0.00004082095,0.00085094775,0.00017692718,0.0004612423,0.000040983046,0.00025676482],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99712175,0.00028841515,0.0013598971,0.00043554985,0.00033443113,0.00045996933],"domain_scores_gemma":[0.9984715,0.0001442742,0.00077073526,0.00047151418,0.00003113199,0.00011086472],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0024027668,0.0004790364,0.0014236583,0.00009490536,0.00008032087,0.000015897736,0.00043528224,0.0005310781,0.0010070531],"category_scores_gemma":[0.00028022807,0.00033517124,0.00044015495,0.00044860505,0.0001562618,0.000009697487,0.000113130045,0.00075719436,0.0000183552],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025057592,0.0008539006,0.00017598373,0.077610314,0.00068764423,0.000014913139,0.0010581957,0.000052928703,0.20614757,0.0005128644,0.009410363,0.7032247],"study_design_scores_gemma":[0.00037557937,0.000082362225,0.0000018224993,0.008125523,0.00028028313,0.000079234946,0.0003625385,0.000008699326,0.012232452,0.000089270405,0.97791153,0.00045067625],"about_ca_topic_score_codex":0.000010084461,"about_ca_topic_score_gemma":0.000020679065,"teacher_disagreement_score":0.9685012,"about_ca_system_score_codex":0.00024822756,"about_ca_system_score_gemma":0.00036569114,"threshold_uncertainty_score":0.99991006},"labels":[],"label_agreement":null},{"id":"W2130802269","doi":"10.1515/bc.2003.012","title":"Biochemical Characterization of β2-Adrenergic Receptor Dimers and Oligomers","year":2003,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Receptor; Chemistry; Lysis; Biochemistry; Denaturation (fissile materials); Dimer; Polyacrylamide gel electrophoresis; Gel electrophoresis; Oligomer; In vitro; Cell surface receptor; Biophysics; Biology; Enzyme; Polymer chemistry; Organic chemistry","score_opus":0.01059916666333294,"score_gpt":0.20995985778856766,"score_spread":0.19936069112523472,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130802269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978792,0.00045348052,0.0004616627,0.000015937625,0.00006694793,0.000062293126,0.00002222538,0.000011922792,0.0010263221],"genre_scores_gemma":[0.99798685,0.00054821593,0.0007406156,0.000061007388,0.0000932211,0.000011014113,0.00031705038,0.000011352209,0.0002306661],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991404,0.000036871228,0.00021298917,0.00034237877,0.0000752744,0.00019207838],"domain_scores_gemma":[0.9995852,0.000009992786,0.0000961556,0.0001593134,0.000044967925,0.00010434207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013258854,0.00015362065,0.00017407024,0.000010254321,0.00003894527,0.000008818444,0.00009830353,0.0003196265,0.00037369254],"category_scores_gemma":[0.00013252544,0.00012571971,0.00007511752,0.00006835843,0.00013364435,0.0000022310908,0.00004947994,0.00007393891,0.000002390191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003321112,0.00003605042,0.000966278,0.000020713464,0.00001988355,3.7626285e-7,0.000006123625,7.6294447e-7,0.9984635,0.0001290874,0.000049353068,0.00027462846],"study_design_scores_gemma":[0.0002294877,0.00007926083,0.00030262454,0.000009888288,0.000006377283,0.000008395836,0.000035754427,0.0000040840323,0.9889516,0.000037501668,0.010168879,0.00016612263],"about_ca_topic_score_codex":0.0000011945026,"about_ca_topic_score_gemma":2.7923251e-8,"teacher_disagreement_score":0.010119527,"about_ca_system_score_codex":0.000007179415,"about_ca_system_score_gemma":0.000024253426,"threshold_uncertainty_score":0.51267016},"labels":[],"label_agreement":null},{"id":"W2131236523","doi":"10.1017/s1461145708009012","title":"Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder","year":2008,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Center for Research Resources; National Institutes of Health; National Institute of Mental Health; Eli Lilly and Company","keywords":"Prefrontal cortex; Major depressive disorder; 5-HT1A receptor; Internal medicine; Endocrinology; Psychology; Receptor; Dorsolateral prefrontal cortex; Neuroscience; Biology; 5-HT receptor; Medicine; Serotonin; Amygdala; Cognition","score_opus":0.015482597069599003,"score_gpt":0.26642419969639203,"score_spread":0.25094160262679305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131236523","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99748766,0.0010495341,0.0002947682,0.00048827578,0.00032451178,0.00022431609,0.0000068399395,0.0000010317179,0.00012306904],"genre_scores_gemma":[0.9975447,0.0014417227,0.00024477122,0.0005090686,0.00020658554,0.000014198551,0.0000040098926,0.000012398474,0.000022516633],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99895203,0.00021424273,0.00031752017,0.00014832409,0.00024242968,0.00012546509],"domain_scores_gemma":[0.99939144,0.000057955604,0.00027044816,0.000096115466,0.00014020845,0.000043849395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024069262,0.00010733296,0.00013844417,0.00008895283,0.00003872012,0.000010228075,0.00046656406,0.000047774858,0.00009033162],"category_scores_gemma":[0.000036628364,0.00006234183,0.000049790262,0.0000740011,0.0001274911,0.000010741317,0.00005227225,0.00022939732,7.420448e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024098444,0.00021676069,0.0071575237,0.000002927276,0.00008364423,0.00017660708,0.0005096447,0.0001574114,0.9882622,0.000046700938,0.00034093,0.00063581753],"study_design_scores_gemma":[0.022528812,0.0038885265,0.5106113,0.00011442551,0.00009828755,0.007920443,0.0013678324,0.00024066302,0.4390601,0.0006328632,0.013014526,0.0005222042],"about_ca_topic_score_codex":0.000021354459,"about_ca_topic_score_gemma":0.000032575797,"teacher_disagreement_score":0.5492021,"about_ca_system_score_codex":0.000012716295,"about_ca_system_score_gemma":0.0000909747,"threshold_uncertainty_score":0.2542226},"labels":[],"label_agreement":null},{"id":"W2132127856","doi":"10.1124/mol.105.019844","title":"Molecular Determinants in the Second Intracellular Loop of the 5-Hydroxytryptamine-1A Receptor for G-Protein Coupling","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"National Institute of Mental Health","keywords":"G protein-coupled receptor; Biophysics; G protein; Chemistry; Receptor; Allosteric regulation; Signal transduction; Adenylyl cyclase; Agonist; Protein subunit; Stereochemistry; Cell biology; Biology; Biochemistry","score_opus":0.006943933593932165,"score_gpt":0.24907968578154502,"score_spread":0.24213575218761285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132127856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9871707,0.0013540481,0.009509147,0.00027330517,0.0003878484,0.0011577219,0.000033592285,0.000007537592,0.000106129046],"genre_scores_gemma":[0.9978463,0.000011460207,0.00061727944,0.00068518036,0.00018217128,0.0002567597,0.00003908932,0.000047819958,0.00031393796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982146,0.00020073705,0.00047921084,0.00044695585,0.00020106137,0.00045741157],"domain_scores_gemma":[0.99918836,0.00002880168,0.0002320551,0.00040861525,0.000101215,0.000040927676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058637775,0.00025941356,0.00027574855,0.000063692496,0.00010774612,0.000020172192,0.00066860113,0.00025658074,0.00016855152],"category_scores_gemma":[0.000040578303,0.00019087004,0.00026340486,0.0002006204,0.00013842752,0.00000514424,0.00013576885,0.00021117034,0.0000031659195],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000917289,0.00011889862,0.00015151565,0.000058569596,0.000039206257,0.000019585414,0.000023501923,0.0023755133,0.9959001,0.00043428072,0.0005964858,0.00019062463],"study_design_scores_gemma":[0.0012150697,0.00021466755,0.000036764493,0.000019100005,0.000044121378,0.000014417722,0.00004685007,0.0024754247,0.98359877,0.00038790633,0.011725814,0.00022107351],"about_ca_topic_score_codex":0.000026770585,"about_ca_topic_score_gemma":0.000031206175,"teacher_disagreement_score":0.012301299,"about_ca_system_score_codex":0.00002257309,"about_ca_system_score_gemma":0.00008456166,"threshold_uncertainty_score":0.77834547},"labels":[],"label_agreement":null},{"id":"W2132762811","doi":"10.1210/en.2003-1185","title":"Ligand-Selective Dissociation of Activation and Internalization of the Parathyroid Hormone (PTH) Receptor: Conditional Efficacy of PTH Peptide Fragments","year":2004,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Biological Sciences","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Internalization; Parathyroid hormone receptor; Parathyroid hormone; G protein-coupled receptor; Receptor; Endocytosis; Chemistry; Cell biology; Endocrinology; Biology; Internal medicine; Calcium; Biochemistry; Hormone receptor; Medicine","score_opus":0.007008532488881715,"score_gpt":0.23674476645375903,"score_spread":0.2297362339648773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132762811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98658025,0.00021519681,0.012844144,0.000046180372,0.000060981863,0.00013567197,0.00002001208,0.0000026774487,0.00009485341],"genre_scores_gemma":[0.9992867,0.00019731495,0.0002702925,0.000022388662,0.00004321463,0.0000054375355,0.00012371094,0.0000070982633,0.00004385295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993897,0.000050192208,0.00022457495,0.00013881132,0.000098310964,0.000098409066],"domain_scores_gemma":[0.99946517,0.000019305877,0.0002700382,0.00009691699,0.00013382155,0.000014738322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000050398678,0.00007462326,0.00013257725,0.00003538809,0.000034884473,0.0000022803752,0.000078979065,0.00007396049,0.000009114067],"category_scores_gemma":[0.00011415981,0.00006244517,0.000048102054,0.00007703506,0.00008132383,0.0000061128444,0.000048905964,0.000053912747,5.1854585e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012276635,0.000074445255,0.0026506344,0.000007106277,0.000068113004,6.297357e-8,0.00021436297,0.00048503114,0.99307126,0.003069618,0.00009312402,0.00014345105],"study_design_scores_gemma":[0.0010015849,0.0003504819,0.028376576,0.000017502,0.000014283135,0.0000031206703,0.00008112147,0.00000935147,0.96847,0.001501773,0.00012262752,0.000051586983],"about_ca_topic_score_codex":0.00002899826,"about_ca_topic_score_gemma":0.00000375571,"teacher_disagreement_score":0.025725942,"about_ca_system_score_codex":0.000019771473,"about_ca_system_score_gemma":0.000041987852,"threshold_uncertainty_score":0.254644},"labels":[],"label_agreement":null},{"id":"W2133428384","doi":"10.1016/s0960-894x(01)00778-8","title":"New Generation Dopaminergic Agents. Part 8: Heterocyclic Bioisosteres that Exploit the 7-OH-2-(aminomethyl)chroman D2 Template","year":2002,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Derivative (finance); Stereochemistry; Dopaminergic; Resolution (logic); Bicyclic molecule; Combinatorial chemistry; Chemical synthesis; Dopamine; In vitro; Biochemistry","score_opus":0.05018907009406931,"score_gpt":0.2330683860108327,"score_spread":0.1828793159167634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133428384","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905086,0.0023920187,0.002325725,0.0035971515,0.000569749,0.00019901303,0.000012151488,0.000043565673,0.00035198644],"genre_scores_gemma":[0.9908032,0.0005320713,0.00023445267,0.0028031573,0.0031792994,0.00002461372,0.0002336367,0.00006052512,0.0021290889],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794227,0.000072892995,0.00039489006,0.00066218874,0.00042268232,0.00050505006],"domain_scores_gemma":[0.9988368,0.000020823729,0.00020780924,0.00064793654,0.000032057356,0.00025452868],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020229038,0.00039608096,0.00027278322,0.000033588574,0.00023410338,0.00008475432,0.00052651117,0.00023926355,0.0029247936],"category_scores_gemma":[0.000051047053,0.00030057918,0.00017277167,0.00015230352,0.00011853624,0.000014404862,0.00012967366,0.000255602,0.0000787523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012174056,0.000027371338,0.0001209479,0.000025506704,0.00008326705,0.000019557097,0.00012460313,0.000009289695,0.9377891,0.0000016137529,0.05921031,0.002576293],"study_design_scores_gemma":[0.00064471015,0.00007487564,0.00009100119,0.000036536843,0.00006504577,0.000116473144,0.0001630941,0.000118098316,0.9294367,0.000004044644,0.06890109,0.00034834625],"about_ca_topic_score_codex":0.00003266756,"about_ca_topic_score_gemma":0.0000058533788,"teacher_disagreement_score":0.00969078,"about_ca_system_score_codex":0.000051311596,"about_ca_system_score_gemma":0.000021956472,"threshold_uncertainty_score":0.9999446},"labels":[],"label_agreement":null},{"id":"W2133472934","doi":"10.1124/jpet.109.153460","title":"Rab1 GTPase and Dimerization in the Cell Surface Expression of Angiotensin II Type 2 Receptor","year":2009,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Louisiana State University","keywords":"GTPase; Cell biology; Receptor; Small GTPase; Chemistry; Angiotensin II; Cell; Signal transduction; Biology; Biochemistry","score_opus":0.013856240888936944,"score_gpt":0.2990673503077435,"score_spread":0.28521110941880656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133472934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897475,0.009567941,0.000118141535,0.00028348522,0.00018951937,0.00006423093,0.0000010385569,7.7779e-7,0.000027365058],"genre_scores_gemma":[0.9961636,0.0016505389,0.0010608238,0.0010018602,0.000091896894,2.71816e-7,0.0000031613931,0.0000045173297,0.000023348064],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994999,0.00010141816,0.00018128872,0.00007379055,0.00006419884,0.00007940972],"domain_scores_gemma":[0.9997519,0.000013820075,0.0001350618,0.00003763477,0.00003881004,0.000022740393],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019843745,0.00007292432,0.00010971314,0.000022711609,0.00005547301,0.00000560703,0.00006606307,0.00007803874,0.00003309693],"category_scores_gemma":[0.0000018796792,0.00005053846,0.000028445163,0.00004385806,0.00004302947,0.000007330931,0.000020633637,0.000085659194,1.1987031e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044011147,0.00016532301,0.00008646599,0.0000021601093,0.0000130954095,0.0000018782459,0.00088707986,0.00006225778,0.99760294,0.000010454026,0.0003777152,0.00035051795],"study_design_scores_gemma":[0.00085003756,0.0014686935,0.00007355038,0.00000749367,0.000018664468,0.000022130995,0.00055340293,0.000055836634,0.9938252,0.000028622719,0.003042191,0.000054189437],"about_ca_topic_score_codex":7.902235e-7,"about_ca_topic_score_gemma":7.0701496e-8,"teacher_disagreement_score":0.007917401,"about_ca_system_score_codex":0.0000047409812,"about_ca_system_score_gemma":0.000019082641,"threshold_uncertainty_score":0.20608987},"labels":[],"label_agreement":null},{"id":"W2133487229","doi":"10.1210/me.2013-1085","title":"Minireview: The Effects of Species Ortholog and SNP Variation on Receptors for Free Fatty Acids","year":2013,"lang":"en","type":"review","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Glasgow; Wellcome Trust; Canadian Institutes of Health Research; Strategiske Forskningsråd","keywords":"Biology; Receptor; SNP; Phenotype; GPR120; Single-nucleotide polymorphism; Hormone; G protein-coupled receptor; Gene; Computational biology; Ligand (biochemistry); Hormone receptor; Genetics; Biochemistry; Genotype","score_opus":0.029271135893340877,"score_gpt":0.2949216998889559,"score_spread":0.26565056399561504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133487229","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012490709,0.9900387,0.005652584,0.000060777133,0.00081024575,0.001981483,0.000038023292,0.000012604771,0.00015650655],"genre_scores_gemma":[0.00021992551,0.9964007,0.0015582149,0.00015556952,0.00019873388,0.00075670384,0.00022392054,0.00006908468,0.00041714407],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99790096,0.00040015965,0.00053510565,0.00062393764,0.0001311443,0.00040867104],"domain_scores_gemma":[0.99835753,0.00021511386,0.0004337402,0.0008376137,0.0000981121,0.00005785602],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017364633,0.000457237,0.0010904276,0.000102342165,0.00009184597,0.000023333128,0.0005171512,0.00043933888,0.000038966467],"category_scores_gemma":[0.00067935913,0.00030771334,0.0005038849,0.00009660233,0.00015673213,0.0000028114396,0.00028070182,0.00022190111,0.000008464294],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031589203,0.00008988468,0.000005362359,0.01123699,0.0008099611,0.000016841874,0.00004568087,0.000002009287,0.09378959,0.009714272,0.0029394072,0.8813184],"study_design_scores_gemma":[0.00038348738,0.00088540645,0.000006241632,0.0007899488,0.00047041348,0.00004755821,0.000007233613,0.0000010635152,0.0591781,0.000305634,0.93762714,0.00029775375],"about_ca_topic_score_codex":0.0000059453932,"about_ca_topic_score_gemma":0.0000018042692,"teacher_disagreement_score":0.93468773,"about_ca_system_score_codex":0.000018269158,"about_ca_system_score_gemma":0.00007073457,"threshold_uncertainty_score":0.9999375},"labels":[],"label_agreement":null},{"id":"W2133754427","doi":"10.1371/journal.pone.0140661","title":"Effect of C-Terminal S-Palmitoylation on D2 Dopamine Receptor Trafficking and Stability","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Institutes of Health; Pennsylvania Department of Health","keywords":"Palmitoylation; Dopamine receptor D2; Immunoprecipitation; Cell biology; G protein-coupled receptor; Biology; Chemistry; Biochemistry; Receptor; Cysteine; Gene; Enzyme","score_opus":0.031379255838522226,"score_gpt":0.24491639830187265,"score_spread":0.21353714246335043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2133754427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99916184,0.00018961054,0.00013360936,0.00001804997,0.000058063444,0.00017770748,0.0000072820008,0.000008194853,0.00024565833],"genre_scores_gemma":[0.99883795,0.00002227409,0.0008314796,0.000011010483,0.000196397,0.000009774641,0.0000440638,0.0000111133595,0.000035965935],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992931,0.00010092291,0.00013869957,0.00019983179,0.00016312608,0.00010433898],"domain_scores_gemma":[0.9996224,0.000028899576,0.000064402426,0.00014837601,0.000065940716,0.00006995566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004361902,0.000094231866,0.00016066576,0.000021935195,0.00002408477,0.0000087039225,0.00005161126,0.0000820874,0.000030752035],"category_scores_gemma":[0.00017500913,0.00008124932,0.000030062372,0.000025853778,0.000029904842,0.0000029964733,0.0000285216,0.000052592255,0.0000030752485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003290607,0.00016495776,0.002275001,0.00008068197,0.00003471569,4.3825602e-7,0.000052017724,0.0000071592035,0.9938387,0.000013386811,0.000015787436,0.0031880513],"study_design_scores_gemma":[0.0005509543,0.0027367938,0.00012860294,0.000057247868,0.00003195706,0.0000010003612,0.00002492366,0.00020083104,0.99610204,0.0000074745467,0.00007417016,0.00008401577],"about_ca_topic_score_codex":0.000004008872,"about_ca_topic_score_gemma":0.0000016508012,"teacher_disagreement_score":0.0031040355,"about_ca_system_score_codex":0.000010671944,"about_ca_system_score_gemma":0.000016890994,"threshold_uncertainty_score":0.3313251},"labels":[],"label_agreement":null},{"id":"W2134355136","doi":"10.1007/s00210-003-0742-3","title":"Calcium-dependent, D2 receptor-independent induction of c-fos by haloperidol in dopamine neurons","year":2003,"lang":"en","type":"article","venue":"Naunyn-Schmiedeberg s Archives of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec; Université de Montréal; Université Laval; Cegep Edouard Montpetit","funders":"Canadian Institutes of Health Research","keywords":"Dopamine receptor D2; Dopaminergic; Haloperidol; Ventral tegmental area; Chemistry; SCH-23390; Dopamine receptor; Receptor antagonist; Dopamine; Internal medicine; Endocrinology; Pharmacology; Receptor; Biology; Antagonist; Medicine; Biochemistry","score_opus":0.013341271122585489,"score_gpt":0.27323310898910264,"score_spread":0.25989183786651715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134355136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905599,0.0012757438,0.003138587,0.00013267946,0.0009903283,0.00044453717,0.000059053036,0.000012434895,0.0033867434],"genre_scores_gemma":[0.99642587,0.0007749473,0.0013050754,0.0001505784,0.000141295,0.00005843527,0.00009554818,0.000043003503,0.0010052602],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99766654,0.00046127182,0.0006525585,0.00055766053,0.0002152041,0.00044675794],"domain_scores_gemma":[0.99919635,0.0000707635,0.00030127465,0.00024980944,0.000063749816,0.00011805753],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003252854,0.0002827195,0.00042783396,0.00021585602,0.00006126833,0.0000075262287,0.00033957706,0.00022753574,0.0007793879],"category_scores_gemma":[0.000082390696,0.00028849798,0.00016245974,0.00016776181,0.00017868745,0.00001177921,0.0001244304,0.0003155796,0.000005862268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003686947,0.00037357662,0.0007284151,0.00004797966,0.000099337456,0.000004445621,0.000117449476,0.0004359725,0.9926556,0.00025320772,0.002243244,0.0026720874],"study_design_scores_gemma":[0.002068826,0.00054924376,0.00015149858,0.000017931176,0.000034166245,0.000016886097,0.000110214896,0.00009572752,0.97295666,0.00010534243,0.023646342,0.00024714967],"about_ca_topic_score_codex":0.000093849885,"about_ca_topic_score_gemma":0.00003511395,"teacher_disagreement_score":0.021403098,"about_ca_system_score_codex":0.000020549287,"about_ca_system_score_gemma":0.00014427525,"threshold_uncertainty_score":0.9999567},"labels":[],"label_agreement":null},{"id":"W2134361179","doi":"10.1139/y02-058","title":"Interaction of a non-peptide agonist with angiotensin II AT<sub>1</sub>receptor mutants","year":2002,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Agonist; Angiotensin II; Receptor; Peptide; Mutant; Chemistry; Endocrinology; Internal medicine; Cell biology; Biology; Biochemistry; Medicine; Gene","score_opus":0.009076450415667858,"score_gpt":0.22820274062704773,"score_spread":0.2191262902113799,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134361179","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998301,0.0006547292,0.000078713296,0.00022959035,0.00050907006,0.00007731076,0.000023165403,0.0000012828897,0.00012508183],"genre_scores_gemma":[0.998626,0.0002532439,0.00019668523,0.0003999125,0.00038164522,0.0000024252133,0.000014117545,0.000014919402,0.000111071444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917674,0.000087219036,0.00025771747,0.0001748913,0.000045264216,0.00025814085],"domain_scores_gemma":[0.999202,0.000018893055,0.00027256922,0.00007757945,0.00015774107,0.00027117724],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011278086,0.000140085,0.000264129,0.000113526425,0.00017943689,0.000004576342,0.00011099595,0.0001584822,0.0015350445],"category_scores_gemma":[0.000012174214,0.000120215605,0.000081857324,0.00006774552,0.00021219812,0.00000943253,0.000027137683,0.00018400638,0.000007775902],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023485268,0.00002835058,0.00014726588,0.000015960652,0.0001781138,0.000023753153,0.00016975039,0.00012474105,0.98767525,0.0000048353927,0.010240997,0.0011561485],"study_design_scores_gemma":[0.00081185525,0.0014289181,0.00036873427,0.000020415997,0.000059477286,0.000291307,0.000043002787,0.000120571414,0.9805115,0.00002402917,0.016195182,0.00012500068],"about_ca_topic_score_codex":0.00007662057,"about_ca_topic_score_gemma":0.00051306153,"teacher_disagreement_score":0.007163725,"about_ca_system_score_codex":0.000030913623,"about_ca_system_score_gemma":0.00013895892,"threshold_uncertainty_score":0.99937767},"labels":[],"label_agreement":null},{"id":"W2134454524","doi":"10.1002/jemt.10337","title":"Mechanism of action of ACTH: Beyond cAMP","year":2003,"lang":"en","type":"review","venue":"Microscopy Research and Technique","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Heart And Stroke Foundation Of Quebec; Institut National de la Santé et de la Recherche Médicale","keywords":"Second messenger system; Cyclic adenosine monophosphate; Secretion; Diacylglycerol kinase; Endocrinology; Protein kinase A; Biology; Internal medicine; Adrenal cortex; Cell biology; Protein kinase C; Signal transduction; Chemistry; Kinase; Receptor; Biochemistry; Medicine","score_opus":0.08688133296987088,"score_gpt":0.4298982490938214,"score_spread":0.3430169161239505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134454524","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003729613,0.9884721,0.009186367,0.0000020411858,0.000073653915,0.0011277935,0.000103536004,0.000007696279,0.0006538739],"genre_scores_gemma":[0.0005274351,0.9927621,0.00565594,0.000003841151,0.000052550997,0.00018938098,0.00013316874,0.000049300877,0.00062629726],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827105,0.00028375888,0.0004427251,0.00043187727,0.00023603466,0.00033454192],"domain_scores_gemma":[0.99896544,0.000037964677,0.00023015167,0.0004327098,0.00024014324,0.00009358514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012162348,0.00024348062,0.0007543225,0.0002647657,0.00008076113,0.00001916079,0.00027223353,0.00068007625,0.00008637005],"category_scores_gemma":[0.0000605298,0.00020677684,0.00020178805,0.00025277215,0.00017743332,0.0000033664066,0.00018293287,0.00041443473,0.0000021327537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016906415,0.000052452615,3.9848214e-7,0.004532632,0.000058921218,0.0000012888156,0.0000057128,9.602303e-9,0.90870076,0.0009985656,0.00038648237,0.085245885],"study_design_scores_gemma":[0.00005226682,0.00047264417,1.3750793e-8,0.0009709616,0.000020792788,0.00001693481,0.000010950207,8.466502e-8,0.60696834,0.0008566497,0.39052683,0.0001035007],"about_ca_topic_score_codex":0.000026087704,"about_ca_topic_score_gemma":0.0000045287416,"teacher_disagreement_score":0.39014035,"about_ca_system_score_codex":0.000024621579,"about_ca_system_score_gemma":0.00032002086,"threshold_uncertainty_score":0.8432115},"labels":[],"label_agreement":null},{"id":"W2134817662","doi":"10.1002/elps.200600571","title":"A CE assay for the detection of agonist‐stimulated adenylyl cyclase activity","year":2007,"lang":"en","type":"article","venue":"Electrophoresis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Chemistry; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Science Foundation","keywords":"Adenylyl cyclase; Terbutaline; Forskolin; Chemistry; Agonist; G protein-coupled receptor; Receptor; Antagonist; G protein; Molecular biology; Internal medicine; Biochemistry; Biology; Medicine","score_opus":0.007992952829532309,"score_gpt":0.24646283290779075,"score_spread":0.23846988007825845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2134817662","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6668854,0.000860385,0.3318137,0.00003376649,0.000095510986,0.00020932521,0.0000063541675,0.000008313122,0.000087299544],"genre_scores_gemma":[0.998906,0.00014361794,0.00042717048,0.00004026609,0.00018768605,0.000019470232,0.000011496284,0.000020245345,0.00024402753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992427,0.000039644514,0.00014458863,0.00020856378,0.00010752528,0.00025693397],"domain_scores_gemma":[0.9994629,0.00008802055,0.00009500195,0.00021768887,0.000094944065,0.000041443625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000518745,0.000109929286,0.0001119387,0.000033683355,0.0001454234,0.0000131600755,0.00012490354,0.00013572609,0.000027237245],"category_scores_gemma":[0.00013635262,0.000083249375,0.00013565419,0.00011731856,0.000035848945,0.000002082253,0.00002375146,0.00008018443,0.0000010604067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005989095,0.000031964213,0.000016144231,0.000008034929,0.00006470897,6.197753e-7,0.000015157538,0.00005321517,0.97565377,0.000027644983,0.000109805515,0.023420004],"study_design_scores_gemma":[0.00029770497,0.00047593037,0.0005170418,0.0000034002844,0.00003776544,0.000004333535,0.000023799012,0.0007752607,0.99259293,0.00007946555,0.0050918153,0.00010055668],"about_ca_topic_score_codex":0.000053228683,"about_ca_topic_score_gemma":0.000074764015,"teacher_disagreement_score":0.33202067,"about_ca_system_score_codex":0.00002343345,"about_ca_system_score_gemma":0.000040413794,"threshold_uncertainty_score":0.33948112},"labels":[],"label_agreement":null},{"id":"W2135020482","doi":"10.1124/mol.106.033670","title":"Activation of the Angiotensin II Type 1 Receptor Leads to Movement of the Sixth Transmembrane Domain: Analysis by the Substituted Cysteine Accessibility Method","year":2007,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Transmembrane domain; Cysteine; Angiotensin II; Transmembrane protein; Chemistry; Domain (mathematical analysis); Receptor; Biophysics; Biochemistry; Biology; Mathematics; Mathematical analysis","score_opus":0.009299524320698697,"score_gpt":0.29789726092038243,"score_spread":0.28859773659968374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135020482","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.895349,0.00019593915,0.102114886,0.0014389069,0.00030661278,0.00050709216,0.000026899746,0.000004283723,0.000056334473],"genre_scores_gemma":[0.9960062,0.000011192353,0.0019656373,0.0017679813,0.000058572303,0.000012651021,0.000041180047,0.000015226475,0.000121382254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836355,0.0004230609,0.00039585313,0.0003270629,0.00024826845,0.00024221258],"domain_scores_gemma":[0.99897736,0.000037849728,0.00022809833,0.00047630217,0.0002266686,0.000053742184],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010606997,0.00016412925,0.00025966586,0.000054246888,0.00015011585,0.0000059504514,0.0005295265,0.00015065442,0.00017726318],"category_scores_gemma":[0.000045559314,0.00009300508,0.000304989,0.0008575859,0.000112019035,0.000003946738,0.00018247133,0.00013760904,4.8928416e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028489265,0.00010179119,0.00023225498,0.0000113439655,0.0005013688,3.175613e-7,0.00015488332,0.0029297543,0.9945558,0.00008148616,0.0005624785,0.0005836586],"study_design_scores_gemma":[0.0004895995,0.00016810677,0.00063136104,0.000005532045,0.00031993678,7.906015e-7,0.000045925375,0.00013312827,0.99477,0.00004959086,0.0032828427,0.000103193684],"about_ca_topic_score_codex":0.00008101503,"about_ca_topic_score_gemma":0.000034605775,"teacher_disagreement_score":0.100657135,"about_ca_system_score_codex":0.000030924,"about_ca_system_score_gemma":0.00006703675,"threshold_uncertainty_score":0.3792637},"labels":[],"label_agreement":null},{"id":"W2135333567","doi":"10.1109/isspit.2005.1577208","title":"A new neural network ensemble heuristic for a predictor of the aldose reductase inhibitory activity","year":2006,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Aldose reductase; Artificial neural network; Mechanism (biology); Computer science; Inhibitory postsynaptic potential; Generalization; Artificial intelligence; Heuristic; Set (abstract data type); Machine learning; Chemistry; Mathematics; Enzyme; Neuroscience; Biology; Biochemistry","score_opus":0.007418043643926373,"score_gpt":0.21757196505523532,"score_spread":0.21015392141130895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135333567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9687112,0.00032950463,0.029615266,0.00010796178,0.0004649119,0.00031122143,0.00001649062,0.000010093122,0.00043337842],"genre_scores_gemma":[0.99256575,0.0000051370953,0.0032735432,0.00007032858,0.0011996798,0.000015557254,0.000020172001,0.000016140695,0.0028337121],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993188,0.000037394333,0.00015108842,0.00020411058,0.000090389345,0.0001982203],"domain_scores_gemma":[0.99956363,0.000017053764,0.00008861713,0.00024065124,0.000043982818,0.000046081055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010841706,0.00010673588,0.000114905575,0.0000090245985,0.00007370914,0.000011380002,0.0001269784,0.00009237327,0.000037926384],"category_scores_gemma":[0.00003321566,0.00007536768,0.00014251721,0.00005666759,0.000027789418,0.0000023986686,0.00006513393,0.000049016133,5.39159e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010792977,0.000033140812,0.00013294944,0.000012436389,0.00001395007,2.2871158e-7,0.000006937988,0.0012620268,0.9536199,0.00040420992,0.043366577,0.0010396957],"study_design_scores_gemma":[0.000518884,0.00018711301,0.00033170273,0.000011499432,0.000022706497,0.000004418791,0.000009685703,0.00084136025,0.9900924,0.001287436,0.006588666,0.00010414725],"about_ca_topic_score_codex":0.00012941436,"about_ca_topic_score_gemma":0.00005140572,"teacher_disagreement_score":0.03677791,"about_ca_system_score_codex":0.0000066306525,"about_ca_system_score_gemma":0.00008826832,"threshold_uncertainty_score":0.30734047},"labels":[],"label_agreement":null},{"id":"W2135488334","doi":"10.1124/mol.114.097337","title":"Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity","year":2015,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Functional selectivity; Angiotensin II; MAPK/ERK pathway; Signal transduction; Receptor; Cell biology; Angiotensin II receptor type 1; Protein kinase C; Heterotrimeric G protein; G protein-coupled receptor; Gq alpha subunit; Chemistry; Biology; G protein; Biochemistry","score_opus":0.017882987552740526,"score_gpt":0.2624441196140655,"score_spread":0.24456113206132496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135488334","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98482674,0.00023431052,0.013768195,0.00016214781,0.00061086955,0.00030341046,0.000016150028,0.000014450934,0.00006371821],"genre_scores_gemma":[0.9979908,0.000029368508,0.00084782334,0.00060108374,0.00013283372,0.000042136628,0.00023072121,0.000036858484,0.00008835972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841714,0.00027078006,0.00034295162,0.00043988464,0.0002016015,0.0003276492],"domain_scores_gemma":[0.99926025,0.0000068964478,0.00016951351,0.00018950576,0.00023823795,0.00013557155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039210936,0.00020975243,0.00028484184,0.00013934252,0.00004527319,0.000007985568,0.00015958233,0.00025340167,0.00012905347],"category_scores_gemma":[0.00006148741,0.00023074009,0.00011194976,0.00024683576,0.00006850466,0.000010320435,0.00016322173,0.00014003075,0.00000769752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028214662,0.0001794842,0.0014332575,0.000010614978,0.000055598237,0.00002804466,0.000056862013,0.00032570426,0.9964338,0.000044206798,0.00040441845,0.00074585935],"study_design_scores_gemma":[0.0014456881,0.00046765595,0.00073235645,0.000010121031,0.00002881631,0.000012815849,0.000016057047,0.00064954854,0.9924659,0.00007804391,0.0038674013,0.00022556621],"about_ca_topic_score_codex":0.000022389704,"about_ca_topic_score_gemma":0.000011811899,"teacher_disagreement_score":0.013164068,"about_ca_system_score_codex":0.00004854777,"about_ca_system_score_gemma":0.00019464194,"threshold_uncertainty_score":0.9409308},"labels":[],"label_agreement":null},{"id":"W2135668812","doi":"10.1002/path.2414","title":"Expression of G protein‐coupled receptor kinase 4 is associated with breast cancer tumourigenesis","year":2008,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Ministry of Education, Culture, Sports, Science and Technology; Japan Health Sciences Foundation","keywords":"G protein-coupled receptor kinase; G protein-coupled receptor; Phosphorylation; Kinase; Cell biology; Cancer research; MAPK/ERK pathway; Protein kinase A; Biology; Signal transduction","score_opus":0.011042238097116333,"score_gpt":0.22907233699686017,"score_spread":0.21803009889974384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135668812","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973465,0.0009938988,0.0011912648,0.0002169865,0.00009996329,0.000103454404,0.0000268024,0.000002357365,0.00001873012],"genre_scores_gemma":[0.99834573,0.00054019183,0.0005793132,0.00010606082,0.00017345832,0.0000050357503,0.000004303272,0.000018024628,0.00022789827],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904805,0.00020826994,0.00030002615,0.000103813756,0.00017692207,0.00016291402],"domain_scores_gemma":[0.9989137,0.000017213168,0.0005485433,0.00016364222,0.0003024839,0.000054437565],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045287248,0.000115427305,0.00024233165,0.000041132073,0.000094512536,0.0000026083044,0.00021193089,0.000121306606,0.0002645355],"category_scores_gemma":[0.00004908843,0.00006542821,0.000088784815,0.00007897351,0.00011421881,0.000004391764,0.00004161968,0.00012642516,0.0000011469293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005215168,0.000072190065,0.000846321,0.000005547972,0.000046734487,0.000040292372,0.0002848675,0.000082212384,0.99752796,0.0000027739807,0.0003899933,0.00017957756],"study_design_scores_gemma":[0.00069032045,0.0006594579,0.0021069117,0.00009473913,0.000041916894,0.0008269687,0.00010693416,0.000011783451,0.99518335,0.00002474324,0.00016310399,0.000089780195],"about_ca_topic_score_codex":0.000014635411,"about_ca_topic_score_gemma":0.000005859476,"teacher_disagreement_score":0.0023446325,"about_ca_system_score_codex":0.000014518203,"about_ca_system_score_gemma":0.00012866592,"threshold_uncertainty_score":0.28964785},"labels":[],"label_agreement":null},{"id":"W2135773940","doi":"10.1159/000159079","title":"α-Adrenoceptor Responses of an Isolated Human Artery and Blood Pressure","year":2008,"lang":"en","type":"article","venue":"Journal of Vascular Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Prazosin; Phenylephrine; Yohimbine; Internal medicine; Endocrinology; Blood pressure; Alpha (finance); Norepinephrine; Potency; Clonidine; Adrenergic receptor; Alpha-2 adrenergic receptor; Medicine; Agonist; Receptor; Chemistry; Antagonist; Dopamine; In vitro; Biochemistry","score_opus":0.04315762357968698,"score_gpt":0.33303984555322447,"score_spread":0.28988222197353747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135773940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928076,0.006704249,0.00027749795,0.000024174726,0.000038904916,0.00009097644,0.0000041436256,0.0000019558245,0.0000504735],"genre_scores_gemma":[0.9974182,0.0010417958,0.00092225394,0.000010277656,0.00024713532,0.000001537077,0.0000051310485,0.000018627294,0.0003350324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983162,0.00045001882,0.00033179307,0.00017222067,0.00050977623,0.00021997643],"domain_scores_gemma":[0.99885136,0.000028429531,0.00013255513,0.0002574082,0.0005779587,0.0001522651],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017478021,0.00009255536,0.00021794614,0.0001823448,0.0001733508,0.000021890875,0.00023979512,0.0001415335,0.00013624858],"category_scores_gemma":[0.00017729284,0.000076349184,0.00013796592,0.000113807844,0.00015281171,0.0000129125465,0.00008574776,0.00027738404,7.583016e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025017918,0.00016150465,0.0006409648,0.000026953583,0.00035399423,0.000056287477,0.00016960787,0.000020646352,0.9976939,0.000021386393,0.00023074739,0.0003738455],"study_design_scores_gemma":[0.0012002706,0.0037513396,0.0024393715,0.00004970433,0.00007977803,0.00064091553,0.00017274031,0.0000442281,0.9860669,0.00011607787,0.0053274985,0.00011122225],"about_ca_topic_score_codex":0.000014118989,"about_ca_topic_score_gemma":0.00000276817,"teacher_disagreement_score":0.01162703,"about_ca_system_score_codex":0.0000031611346,"about_ca_system_score_gemma":0.0001256927,"threshold_uncertainty_score":0.31134292},"labels":[],"label_agreement":null},{"id":"W2135796764","doi":"10.1054/npep.2000.0814","title":"Effects of angiotensin II on visual evoked potentials in the superior colliculus of juvenile rats","year":2000,"lang":"en","type":"article","venue":"Neuropeptides","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"Medical Research Council Canada; Université de Sherbrooke","keywords":"Superior colliculus; Midbrain; Losartan; Endocrinology; Internal medicine; Microinjection; Angiotensin II; Receptor; Chemistry; Angiotensin receptor; Angiotensin III; Inferior colliculus; Juvenile; Neuroscience; Central nervous system; Biology; Medicine; Nucleus","score_opus":0.005410010459544282,"score_gpt":0.22603626739535895,"score_spread":0.22062625693581467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135796764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990206,0.00021822155,0.000009378679,0.000046975732,0.000061960665,0.0002280488,0.000004642597,0.0000036717988,0.00040649844],"genre_scores_gemma":[0.99909353,0.000115880044,0.00008895241,0.0002545086,0.00007212402,0.0000080910595,0.000008863239,0.00001576669,0.0003422583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911064,0.00017821667,0.00023300241,0.00019223477,0.00014176637,0.00014412486],"domain_scores_gemma":[0.9996672,0.0000353412,0.000060268485,0.00017461045,0.000038707854,0.000023834775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017189105,0.00010984562,0.00018863873,0.00003334885,0.00004689343,0.000008637329,0.00015670122,0.00006556424,0.00008607667],"category_scores_gemma":[0.000063942476,0.00007792468,0.000101196274,0.00011069754,0.00004969563,0.0000026192117,0.000031935473,0.000059031947,0.0000051729444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012997592,0.00014395812,0.00005440162,0.000017966193,0.0000108307395,0.000011824965,0.000116358206,0.0002217145,0.99590486,0.000025282183,0.00032422857,0.0030385864],"study_design_scores_gemma":[0.00038731168,0.001210285,0.0027320255,0.000040257324,0.000012742017,0.0000053428666,0.000026880465,0.00003965827,0.9925828,0.00001431479,0.0028708235,0.00007753841],"about_ca_topic_score_codex":0.000032084972,"about_ca_topic_score_gemma":0.0000055586534,"teacher_disagreement_score":0.0033220523,"about_ca_system_score_codex":0.00000268054,"about_ca_system_score_gemma":0.000022836779,"threshold_uncertainty_score":0.3177676},"labels":[],"label_agreement":null},{"id":"W2135805417","doi":"10.1124/jpet.103.056705","title":"The Thromboxane Receptor Antagonist PBT-3, a Hepoxilin Stable Analog, Selectively Antagonizes the TPα Isoform in Transfected COS-7 Cells","year":2003,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Heart, Lung, and Blood Institute; National Institute for Health and Care Research","keywords":"Antagonist; Gene isoform; Transfection; Chemistry; Pharmacology; Receptor; Receptor antagonist; Biochemistry; Medicine","score_opus":0.012416436173326079,"score_gpt":0.2890059913899419,"score_spread":0.27658955521661577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135805417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.983582,0.01437219,0.00038109667,0.00037696236,0.0009116243,0.00022542871,0.0000080004675,0.0000035437922,0.00013913194],"genre_scores_gemma":[0.99156517,0.0067613027,0.00033024495,0.0010124716,0.00016813488,0.000010600709,0.0000035173498,0.000020207604,0.00012834895],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858993,0.00035750406,0.0004123851,0.00017420495,0.00013825353,0.0003277084],"domain_scores_gemma":[0.9994784,0.00008336424,0.00019493866,0.00008874976,0.0000938732,0.000060695216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000743192,0.00019155789,0.00023515665,0.00004110786,0.00037351385,0.000049483326,0.00021828587,0.00014105068,0.00012715383],"category_scores_gemma":[0.000007371548,0.00011553501,0.00010836112,0.00013284247,0.00022906819,0.000014541094,0.00002630694,0.00032478978,0.0000014706039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006883491,0.00021058442,0.00016095834,0.0000039830047,0.00024930874,0.0000056629938,0.00057166035,0.000043063672,0.9967675,0.00017196215,0.0006948477,0.0004321147],"study_design_scores_gemma":[0.0017096561,0.0009839028,0.00005486242,0.0000061268756,0.00004939975,0.00009847717,0.0018735155,0.00006299727,0.94307256,0.00009947186,0.05185262,0.00013638598],"about_ca_topic_score_codex":0.000007805416,"about_ca_topic_score_gemma":0.000011242001,"teacher_disagreement_score":0.05369492,"about_ca_system_score_codex":0.000050760966,"about_ca_system_score_gemma":0.00014696289,"threshold_uncertainty_score":0.4711381},"labels":[],"label_agreement":null},{"id":"W2135909282","doi":"10.4049/jimmunol.0901618","title":"Maintenance of Immune Tolerance to a Neo-Self Acetylcholine Receptor Antigen with Aging: Implications for Late-Onset Autoimmunity","year":2010,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institute on Aging","keywords":"Self Tolerance; Autoimmunity; Immunology; Acetylcholine receptor; Immune system; Antigen; Biology; Receptor; Genetics","score_opus":0.008264467614778854,"score_gpt":0.2498633660739959,"score_spread":0.24159889845921703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135909282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812611,0.00096145575,0.015273725,0.0018984885,0.0003100056,0.00023447916,0.000026256314,0.0000056789254,0.000028851318],"genre_scores_gemma":[0.98362684,0.0006651131,0.015227355,0.00017345561,0.00011134326,0.000011356815,0.000012596875,0.000021823911,0.00015011273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904984,0.00008427094,0.00045173086,0.00011159755,0.000065097025,0.00023743704],"domain_scores_gemma":[0.9984446,0.000055103024,0.00047735363,0.00046861114,0.0005108601,0.000043458556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082760386,0.00013178057,0.00027542686,0.00005867626,0.00013725912,0.000009833356,0.00058878114,0.000121363926,0.000031993768],"category_scores_gemma":[0.0001407648,0.000085230786,0.00011540277,0.000120511795,0.000120276105,0.000007726661,0.00008735176,0.00029773335,0.0000021004064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006462362,0.00007043741,0.00034400861,0.000006690536,0.00016320134,1.8494563e-7,0.00031496622,0.00014719763,0.9961003,0.00015173371,0.00028444032,0.0017705907],"study_design_scores_gemma":[0.0010705754,0.001306707,0.011092816,0.000044078308,0.000042436357,0.00023678373,0.00018288745,0.000019950914,0.9539841,0.00021217787,0.031666514,0.0001409895],"about_ca_topic_score_codex":0.000024054418,"about_ca_topic_score_gemma":0.000017643846,"teacher_disagreement_score":0.04211623,"about_ca_system_score_codex":0.000010310756,"about_ca_system_score_gemma":0.0001363095,"threshold_uncertainty_score":0.34756106},"labels":[],"label_agreement":null},{"id":"W2136049881","doi":"10.1152/ajpcell.00190.2002","title":"Diacylglycerol and ceramide formation induced by dopamine D2S receptors via Gβγ-subunits in Balb/c-3T3 cells","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Ceramide; Diacylglycerol kinase; Gq alpha subunit; Biology; Lipid signaling; Phospholipase C; Pertussis toxin; G protein; Cell biology; Protein kinase C; Signal transduction; Second messenger system; Protein kinase A; Receptor; Biochemistry; Molecular biology; Kinase; Apoptosis","score_opus":0.004822824010698073,"score_gpt":0.2066849025323825,"score_spread":0.20186207852168442,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136049881","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980953,0.00044822067,0.0006443525,0.00005391091,0.0004668128,0.00015509163,0.000007637535,0.0000062036115,0.00012250314],"genre_scores_gemma":[0.9975671,0.0007894239,0.0008624315,0.00044009168,0.00019154782,0.000010289012,0.00005070192,0.000037364283,0.00005105059],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99769646,0.0006092063,0.000679722,0.0004045708,0.00012775185,0.00048231674],"domain_scores_gemma":[0.99851215,0.00008239606,0.0008055235,0.00026538712,0.00016052272,0.00017399418],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036670515,0.0003263789,0.00067018025,0.00015849348,0.00008393014,0.000013368113,0.0002674721,0.00020057552,0.00009163797],"category_scores_gemma":[0.000065129,0.0002880585,0.00015110215,0.0002504629,0.00026102545,0.000030402112,0.00007447423,0.00039087853,0.000008580265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029945825,0.00015723551,0.000039618863,0.000019772819,0.00004571208,0.000001245241,0.00012445655,0.00026712051,0.99499345,0.00001514033,0.0006249094,0.0034118583],"study_design_scores_gemma":[0.00134071,0.0030046864,0.0006783523,0.000018936249,0.000023781273,0.000033119166,0.0005096112,0.0000839272,0.9890893,0.00048856286,0.00440941,0.00031960863],"about_ca_topic_score_codex":0.00004709966,"about_ca_topic_score_gemma":0.000006860509,"teacher_disagreement_score":0.005904177,"about_ca_system_score_codex":0.000039557366,"about_ca_system_score_gemma":0.000077386416,"threshold_uncertainty_score":0.99995714},"labels":[],"label_agreement":null},{"id":"W2136657751","doi":"10.1074/jbc.m110312200","title":"Functional Consequences of the Loss of High Affinity Agonist Binding to γ-Aminobutyric Acid Type A Receptors","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Muscimol; Agonist; Homologous desensitization; Receptor; GABAA receptor; Desensitization (medicine); Chemistry; Binding site; Biology; Partial agonist; Endocrinology; Biochemistry; Internal medicine; Medicine","score_opus":0.03609758012068664,"score_gpt":0.23783869996710222,"score_spread":0.20174111984641557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136657751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99850523,0.0005146935,0.00015923886,0.00019571879,0.00034193406,0.000042688836,0.00001843876,0.0000020362509,0.00022004303],"genre_scores_gemma":[0.9985756,0.0002064754,0.0006860279,0.000053975727,0.00023717544,0.0000010745748,0.000007305178,0.000005439438,0.00022689621],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990303,0.000053114978,0.00043271316,0.00014824701,0.00019003436,0.00014557708],"domain_scores_gemma":[0.9990392,0.000033347307,0.00044834244,0.00014935572,0.00024494904,0.00008486181],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002751387,0.00011886249,0.00024713977,0.000018645693,0.000057869034,0.000008384632,0.0002988989,0.00020430089,0.00095628994],"category_scores_gemma":[0.00045030777,0.00007095547,0.0001929763,0.00016497134,0.00021286347,0.0000033040913,0.0000938247,0.00016498206,0.0000028753204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011982058,0.00007208677,0.003020004,0.00001765437,0.00004912906,0.0000022142297,0.000013297572,0.00007075618,0.99550503,0.000018265739,0.0008266149,0.00028509996],"study_design_scores_gemma":[0.00022153163,0.00038197156,0.00066985824,0.000038694907,0.000015210893,0.00008098702,0.00008399135,0.0000018399827,0.9970006,0.0000933767,0.0013237983,0.000088193134],"about_ca_topic_score_codex":0.0000029316495,"about_ca_topic_score_gemma":2.5081312e-7,"teacher_disagreement_score":0.0023501455,"about_ca_system_score_codex":0.000018257511,"about_ca_system_score_gemma":0.000053399046,"threshold_uncertainty_score":0.99995697},"labels":[],"label_agreement":null},{"id":"W2137034059","doi":"10.1002/syn.20499","title":"Dopamine D2<sup>High</sup> receptors on intact cells","year":2008,"lang":"en","type":"article","venue":"Synapse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dopamine receptor D2; Raclopride; Dopamine receptor; Receptor; Dopamine; Endocrinology; Domperidone; Neuroscience; Internal medicine; In vitro; Chemistry; Biology; Cell biology; Medicine; Biochemistry","score_opus":0.00940318387001261,"score_gpt":0.2131691573416434,"score_spread":0.2037659734716308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137034059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970278,0.00017288899,0.0006759974,0.000091923226,0.00037196506,0.00014644084,0.00001582164,0.000029321754,0.0014678183],"genre_scores_gemma":[0.99428743,0.00035087965,0.00083009555,0.00030123643,0.00048713747,0.00001615061,0.00013710535,0.00003905132,0.0035508918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988069,0.00006727699,0.00021437783,0.0004227391,0.00017208038,0.00031664988],"domain_scores_gemma":[0.99935204,0.000016631064,0.00006820371,0.00038528698,0.00005208199,0.00012573632],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011887123,0.00021533655,0.0001887661,0.000055480956,0.0001440933,0.0000150495,0.00020949385,0.00020080367,0.0008185292],"category_scores_gemma":[0.00004591813,0.00019013869,0.00012227347,0.000090980044,0.00006118401,0.0000038993103,0.00007422157,0.00014174037,0.00024892107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010620173,0.00010146773,0.00017655888,0.000009003077,0.000050877607,0.000034777637,0.00008955544,0.0006863784,0.98660934,0.0002014351,0.010460012,0.0014744168],"study_design_scores_gemma":[0.00043543873,0.0006831033,0.000064178945,0.000013946636,0.000008978121,0.000035811867,0.00006927102,0.000069568545,0.95064783,0.000054592732,0.047661204,0.0002560482],"about_ca_topic_score_codex":0.000035126683,"about_ca_topic_score_gemma":0.000002809057,"teacher_disagreement_score":0.037201192,"about_ca_system_score_codex":0.000020821673,"about_ca_system_score_gemma":0.00004657651,"threshold_uncertainty_score":0.89623207},"labels":[],"label_agreement":null},{"id":"W2137092708","doi":"10.1074/jbc.m513380200","title":"Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":466,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Xenon Pharmaceuticals (Canada)","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute","keywords":"Parathyroid hormone; MAPK/ERK pathway; Protein kinase C; Signal transduction; Kinase; Protein kinase A; Chemistry; Receptor; Phosphorylation; Internal medicine; HEK 293 cells; Cell biology; Gq alpha subunit; Parathyroid hormone receptor; Endocrinology; G protein-coupled receptor; Arrestin; Biology; Biochemistry; Calcium; Hormone receptor; Medicine","score_opus":0.018059499897010035,"score_gpt":0.23211453842312435,"score_spread":0.21405503852611432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137092708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911228,0.0009733294,0.007391057,0.000067875575,0.000039529343,0.00017840126,0.000025543583,0.0000090522135,0.00019241674],"genre_scores_gemma":[0.9960888,0.00006322006,0.0026944168,0.00002534591,0.00076505897,0.000014977175,0.00012286316,0.0000138094365,0.00021152155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989469,0.000031607153,0.00042854896,0.0002477415,0.0001325174,0.00021268685],"domain_scores_gemma":[0.99919087,0.000035427125,0.00037280723,0.00011343094,0.0001892389,0.000098201424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003304068,0.0001786684,0.00023464492,0.00001467996,0.00009130672,0.000035709774,0.0001435573,0.0003041619,0.000039711493],"category_scores_gemma":[0.00026648087,0.00012951884,0.0001283185,0.000044303684,0.000060027258,0.0000065622717,0.00005104774,0.00016130571,8.006672e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004559649,0.00008723441,0.00019701882,0.000016691141,0.000026967718,0.000003193638,0.0000037474856,0.000044431712,0.9979152,0.000026130705,0.0006512337,0.0005721867],"study_design_scores_gemma":[0.0009759384,0.0006552043,0.00091790996,0.00002599637,0.000012710104,0.000041164683,0.000028197877,0.00005335632,0.9925302,0.00096531253,0.003611009,0.0001829672],"about_ca_topic_score_codex":0.0000030422618,"about_ca_topic_score_gemma":2.1752079e-7,"teacher_disagreement_score":0.005384966,"about_ca_system_score_codex":0.000023893039,"about_ca_system_score_gemma":0.000046335004,"threshold_uncertainty_score":0.5281625},"labels":[],"label_agreement":null},{"id":"W2137163300","doi":"10.1210/mend.14.12.0565","title":"Receptor/β-Arrestin Complex Formation and the Differential Trafficking and Resensitization ofβ<sub>2</sub>-Adrenergic and Angiotensin II Type 1A Receptors","year":2000,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Internalization; Endocytic cycle; Cell biology; Biology; Receptor; Dynamin; Arrestin; G protein-coupled receptor; Endosome; Endocytosis; Signal transduction; Intracellular; Biochemistry","score_opus":0.00869912186092356,"score_gpt":0.210779337097663,"score_spread":0.20208021523673944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137163300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955051,0.001522374,0.0018677122,0.0005645795,0.00016208876,0.00024066008,0.000004267833,0.00002684811,0.000106396714],"genre_scores_gemma":[0.9963773,0.002301966,0.0006254283,0.00030387004,0.00011571984,0.000010278502,0.0001926381,0.000028200115,0.000044616547],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986812,0.00024196952,0.00024648107,0.00039379636,0.00011299452,0.00032359315],"domain_scores_gemma":[0.9995464,0.000023506027,0.000080476995,0.00020114583,0.00007237186,0.000076095006],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011382195,0.00021177635,0.00023297107,0.0000635124,0.0003073499,0.000051327923,0.000080222926,0.00015268769,0.000054303342],"category_scores_gemma":[0.000043876946,0.00017579646,0.00004935377,0.00009537453,0.00026681155,0.000010464453,0.00012713426,0.00012910609,0.0000031368031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003669354,0.000014557214,0.00002442189,0.000009674934,0.00004313685,0.0000071635586,0.00019870531,0.00019260525,0.9562635,0.00088942697,0.00029604812,0.041693814],"study_design_scores_gemma":[0.0023187466,0.00053232076,0.00042574038,0.000023518121,0.000068965484,0.00034986789,0.00012390906,0.0053172316,0.97897667,0.00036816907,0.011160527,0.00033436497],"about_ca_topic_score_codex":0.00002413834,"about_ca_topic_score_gemma":0.000021490938,"teacher_disagreement_score":0.04135945,"about_ca_system_score_codex":0.000009243033,"about_ca_system_score_gemma":0.000014772708,"threshold_uncertainty_score":0.71687716},"labels":[],"label_agreement":null},{"id":"W2137324425","doi":"10.1080/10799890600923161","title":"Synthesis of an Agonistic, Difluoro-Azido Photolabel of Angiotensin II and Labeling of the AT<sub>1</sub>Receptor: Transmembrane Domains 3, 6, and 7 Form the Ligand-Binding Pocket","year":2006,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Photoaffinity labeling; Transmembrane domain; Radioligand; Agonist; Receptor; Stereochemistry; Transmembrane protein; Nitrene; Combinatorial chemistry; Biophysics; Biochemistry; Biology","score_opus":0.005296678289089595,"score_gpt":0.1957606336278905,"score_spread":0.19046395533880092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137324425","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962454,0.0024800738,0.00065977813,0.00016737077,0.00022911116,0.00016189707,0.00004135239,0.0000022851757,0.000012719849],"genre_scores_gemma":[0.99671006,0.0020616658,0.0009785139,0.000013920872,0.00018838675,0.000002075704,0.0000072293533,0.000021353511,0.000016815931],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985954,0.00012531455,0.0006354588,0.00019652786,0.0002717114,0.0001755927],"domain_scores_gemma":[0.9990295,0.00006651826,0.0005266217,0.00012654693,0.00017798971,0.00007281658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069959287,0.00019096679,0.00040328747,0.00008090167,0.00026725532,0.000019119729,0.00012364726,0.00017397583,0.000020631038],"category_scores_gemma":[0.000023269135,0.00012191498,0.00019181502,0.00012194347,0.000262856,0.000029457418,0.00002811589,0.00015229243,3.222894e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036333085,0.00008993772,0.00027273246,0.000086602195,0.000109091685,4.5789463e-7,0.0003579335,0.00008015219,0.98952645,0.000055057648,0.000037688074,0.009020564],"study_design_scores_gemma":[0.0007347581,0.00073924987,0.00039046624,0.00017540682,0.00020988613,0.0001162478,0.00040903097,0.00008463619,0.99643046,0.0001711379,0.000405971,0.00013274689],"about_ca_topic_score_codex":0.00002780503,"about_ca_topic_score_gemma":0.000024333924,"teacher_disagreement_score":0.008887817,"about_ca_system_score_codex":0.000014554124,"about_ca_system_score_gemma":0.000042654083,"threshold_uncertainty_score":0.49715483},"labels":[],"label_agreement":null},{"id":"W2137400811","doi":"10.1007/978-0-387-73657-0_151","title":"Temperature-induced Ligand Contact Point Variations of the hAT1 Receptor and of the Constitutively Active Mutant N111G-hAT1","year":2009,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Mutant; Chemistry; Receptor; Biochemistry; Gene","score_opus":0.012649025086985843,"score_gpt":0.3004141657976464,"score_spread":0.28776514071066056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137400811","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99156916,0.006896504,0.000039133993,0.0004806054,0.00031205654,0.00023126311,0.000019427356,0.0000015818302,0.00045029545],"genre_scores_gemma":[0.9985066,0.00089663744,0.00009632866,0.00040060809,0.000071148614,0.000007628611,0.000008882175,0.0000031805266,0.000008953809],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999367,0.000076800956,0.00020972863,0.00019102232,0.00004828881,0.00010718755],"domain_scores_gemma":[0.9996406,0.000039694187,0.0001353427,0.0001250123,0.00003281455,0.000026527761],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010073727,0.00010869075,0.0002020822,0.00002296972,0.000066018394,0.0000019713368,0.0001016574,0.00009809759,0.000011922875],"category_scores_gemma":[0.00010350659,0.00005628459,0.00003243106,0.0000757,0.00031219076,0.0000088017805,0.00005766159,0.00008310649,4.532869e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009115494,0.00004034234,0.00059452484,0.0000035267203,0.000015220236,1.8158309e-7,0.0004469532,8.776179e-7,0.9918058,0.005306926,0.000010291428,0.001684206],"study_design_scores_gemma":[0.0007869584,0.0010415878,0.0013260436,0.00009362769,0.0000090236545,0.000009587111,0.0016592661,0.0000038307753,0.9933898,0.00062759477,0.0009853137,0.00006739878],"about_ca_topic_score_codex":0.000025219491,"about_ca_topic_score_gemma":0.000014488078,"teacher_disagreement_score":0.0069375,"about_ca_system_score_codex":0.0000091914235,"about_ca_system_score_gemma":0.000031997984,"threshold_uncertainty_score":0.22952189},"labels":[],"label_agreement":null},{"id":"W2137468381","doi":"10.1046/j.1471-4159.2001.00648.x","title":"The cytoplasmic tail of the D1A receptor subtype: identification of specific domains controlling dopamine cellular responsiveness","year":2001,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Adenylyl cyclase; HEK 293 cells; G protein-coupled receptor; Receptor; Cell biology; Agonist; Biology; G protein; Dopamine receptor; Signal transduction; cAMP-dependent pathway; Biochemistry","score_opus":0.008164310101283531,"score_gpt":0.21844793926800965,"score_spread":0.2102836291667261,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137468381","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99520814,0.0019122608,0.0020618523,0.00018934024,0.0004602707,0.00008089247,0.000008738019,0.0000015652704,0.0000769194],"genre_scores_gemma":[0.99733406,0.0015646975,0.000090563786,0.000021273125,0.00033978478,0.0000017297502,0.0000048201814,0.000016887258,0.00062620227],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998563,0.00011738211,0.000715304,0.00014970476,0.0003021702,0.00015246277],"domain_scores_gemma":[0.9979383,0.00008857706,0.0010923193,0.00038655614,0.00044426005,0.000050015107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006492114,0.00012389908,0.00021137901,0.000025329682,0.0001183401,0.000023417433,0.0005033364,0.00010743209,0.000024213254],"category_scores_gemma":[0.00031429596,0.00007992545,0.0002446985,0.00013713838,0.00011814489,0.0000062295558,0.000060702114,0.00018721285,8.1337583e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000563119,0.000043272867,0.00032122165,0.000022151393,0.000041667696,0.000004865706,0.000020149913,0.0002689392,0.99815756,0.00002157126,0.00027881432,0.00025664168],"study_design_scores_gemma":[0.0005576122,0.00010859545,0.00044141346,0.000044203538,0.00002793916,0.00009156042,0.00017933932,0.00002707539,0.98216474,0.00006413194,0.016220018,0.000073357136],"about_ca_topic_score_codex":7.9013387e-7,"about_ca_topic_score_gemma":4.5783887e-7,"teacher_disagreement_score":0.015992831,"about_ca_system_score_codex":0.000016046362,"about_ca_system_score_gemma":0.00011228213,"threshold_uncertainty_score":0.3259265},"labels":[],"label_agreement":null},{"id":"W2137769667","doi":"10.1523/jneurosci.2423-05.2005","title":"The Translation Repressor 4E-BP2 Is Critical for eIF4F Complex Formation, Synaptic Plasticity, and Memory in the Hippocampus","year":2005,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":320,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; FRAXA Research Foundation; Howard Hughes Medical Institute","keywords":"Long-term potentiation; Schaffer collateral; Neuroscience; Synaptic plasticity; Hippocampus; Hippocampal formation; Metaplasticity; LTP induction; Translation (biology); Neuronal memory allocation; Psychology; Biology; Messenger RNA; Excitatory postsynaptic potential; Inhibitory postsynaptic potential; Genetics","score_opus":0.04045220774653451,"score_gpt":0.30591829383018465,"score_spread":0.26546608608365013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137769667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94062275,0.0004071398,0.052841697,0.0057817586,0.00015314706,0.00013803865,0.000003982618,0.0000013180323,0.000050168626],"genre_scores_gemma":[0.99755836,0.00014736102,0.00094611605,0.0012026675,0.00013182823,0.0000032282821,3.5779436e-7,0.000003291354,0.000006792777],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930984,0.000063056665,0.00023912164,0.00009743478,0.00016416436,0.00012636077],"domain_scores_gemma":[0.9995532,0.00017690062,0.00009182433,0.00007193795,0.000072470204,0.000033644563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005645441,0.000053670967,0.000066562774,0.00002260039,0.00019050366,0.00007849701,0.00020511408,0.00003187793,0.0000022271608],"category_scores_gemma":[0.00043115922,0.000030822528,0.000043678767,0.000051812916,0.000106055995,0.00002218092,0.000016644757,0.000081417085,1.7970427e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050606344,0.000021560538,0.000018251196,0.000007188428,0.0000013859436,0.0000011993584,0.00019735418,0.00029051912,0.9894651,0.00019856128,0.0003742095,0.00937405],"study_design_scores_gemma":[0.0034129256,0.003893003,0.014422492,0.00013086174,0.00010952876,0.0023474041,0.0019710201,0.25339222,0.63041824,0.014398333,0.07493775,0.0005662459],"about_ca_topic_score_codex":4.3575758e-7,"about_ca_topic_score_gemma":0.0000043711066,"teacher_disagreement_score":0.3590469,"about_ca_system_score_codex":0.000004639319,"about_ca_system_score_gemma":0.000023957462,"threshold_uncertainty_score":0.14652194},"labels":[],"label_agreement":null},{"id":"W2137900887","doi":"10.1124/mol.113.087783","title":"The Pharmacology of TUG-891, a Potent and Selective Agonist of the Free Fatty Acid Receptor 4 (FFA4/GPR120), Demonstrates Both Potential Opportunity and Possible Challenges to Therapeutic Agonism","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":202,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research","keywords":"Agonism; GPR120; Agonist; Pharmacology; Partial agonist; Receptor; Chemistry; G protein-coupled receptor; Biochemistry; Medicine; Political science","score_opus":0.01179449446762494,"score_gpt":0.251569769564625,"score_spread":0.23977527509700008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137900887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98170245,0.009264983,0.0016715433,0.0052024024,0.000672167,0.0011946935,0.00004311315,0.000011723511,0.00023693434],"genre_scores_gemma":[0.99495673,0.0027968097,0.000674906,0.0011541029,0.00013483469,0.00018004296,0.000010354472,0.00003380455,0.000058390517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979268,0.00056615815,0.00040974544,0.0004696177,0.00018600855,0.00044171835],"domain_scores_gemma":[0.9989058,0.000052623735,0.00026763015,0.00033062213,0.00023542199,0.00020791794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004439637,0.00028431776,0.00034042832,0.00005708954,0.00029272874,0.000031116677,0.00050323235,0.00022885806,0.00011816253],"category_scores_gemma":[0.00005070582,0.00019604049,0.00013871398,0.000119209064,0.00049217284,0.000010299264,0.00049751566,0.00024015248,0.0000018504053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017681555,0.000101236714,0.00008227824,0.000037865255,0.00042020157,0.0000041341536,0.00016798843,0.00003920963,0.9876635,0.0002568961,0.0012651127,0.009784738],"study_design_scores_gemma":[0.0010496962,0.0007009644,0.001348587,0.00001031649,0.00016424539,0.000050761704,0.00033234598,0.00016335459,0.993526,0.0008624355,0.0015826611,0.0002086332],"about_ca_topic_score_codex":0.000062681174,"about_ca_topic_score_gemma":0.0000146148595,"teacher_disagreement_score":0.013254315,"about_ca_system_score_codex":0.000018379009,"about_ca_system_score_gemma":0.00018778117,"threshold_uncertainty_score":0.7994299},"labels":[],"label_agreement":null},{"id":"W2137943404","doi":"10.1016/j.ymeth.2015.09.024","title":"Biasing the odds: Approaches to capturing, understanding and exploiting functional selectivity in GPCRs","year":2015,"lang":"en","type":"review","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Odds; Context (archaeology); Curiosity; Functional selectivity; Computer science; Risk analysis (engineering); Psychology; Data science; Computational biology; G protein-coupled receptor; Neuroscience; Medicine; Biology; Machine learning; Receptor","score_opus":0.715757973071174,"score_gpt":0.4316599337957446,"score_spread":0.28409803927542937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2137943404","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012633104,0.6258299,0.37318942,0.0000165887,0.00017593893,0.00028944275,0.0000032737403,0.0000075671287,0.00036152123],"genre_scores_gemma":[0.0011305799,0.90551555,0.0917975,0.000079717945,0.00083409774,0.00019615763,0.00006946468,0.00010945357,0.0002675065],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99778855,0.0009840401,0.00030077467,0.0005134237,0.00013511648,0.00027811783],"domain_scores_gemma":[0.99937797,0.000145561,0.00013852587,0.00022696906,0.000020142676,0.00009085381],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003647474,0.0002806932,0.00058611506,0.000116261435,0.00013335032,0.00007822495,0.00014783056,0.0002720253,0.000009136136],"category_scores_gemma":[0.0002875404,0.00019902698,0.0001435807,0.00022725019,0.000036874775,0.000004387781,0.00020139273,0.00029951145,0.0000011572544],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009988095,0.00001439498,0.000006582827,0.0007665018,0.000083530846,0.0000015308303,0.00022519148,0.000107654676,0.0010715211,0.00073320296,0.00008339746,0.9968965],"study_design_scores_gemma":[0.00021200336,0.000114744515,0.0000032813084,0.0016861432,0.0001918922,0.00008588983,0.0012658595,0.0002273678,0.0026152045,0.0014465378,0.99151397,0.00063713384],"about_ca_topic_score_codex":0.000020710118,"about_ca_topic_score_gemma":0.00001934593,"teacher_disagreement_score":0.9962594,"about_ca_system_score_codex":0.00013628988,"about_ca_system_score_gemma":0.00015729008,"threshold_uncertainty_score":0.8116085},"labels":[],"label_agreement":null},{"id":"W2138111790","doi":"10.1074/jbc.m009495200","title":"Control of CYP11B2 Gene Expression through Differential Regulation of Its Promoter by Atypical and Conventional Protein Kinase C Isoforms","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Gene isoform; Gene; Biology; Gene expression; Protein kinase A; Molecular biology; Kinase; Genetics; Cell biology","score_opus":0.013031162675795514,"score_gpt":0.2355480318930887,"score_spread":0.2225168692172932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138111790","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.977095,0.0008423952,0.021815715,0.00004955945,0.000031170017,0.00010655922,0.00002549872,0.0000017702713,0.000032301963],"genre_scores_gemma":[0.99834317,0.00017644092,0.0011391682,0.000014180872,0.00018711461,0.0000036166778,0.00004784605,0.0000059197323,0.00008256045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906015,0.000040945626,0.00046530564,0.00015211458,0.00015878514,0.00012269623],"domain_scores_gemma":[0.99920195,0.000011908414,0.00045336815,0.00008364543,0.00018292839,0.000066174995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015964714,0.000116364594,0.00025698918,0.000009174444,0.00002902132,0.0000071593054,0.00011010902,0.00026868022,0.00040214747],"category_scores_gemma":[0.00009667565,0.00007568408,0.00013727634,0.000028881463,0.00008870165,0.00000873686,0.0000456754,0.00011183739,2.0227252e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001047855,0.00016446349,0.00080514356,0.00004507801,0.000038267022,0.0000021870187,0.0000062143195,0.000005997651,0.9975171,0.000017605385,0.00006131514,0.00028878686],"study_design_scores_gemma":[0.0013164114,0.00051736453,0.0008734773,0.00007912387,0.0000145349995,0.000057481127,0.000012985619,0.000052160583,0.9961876,0.0003045522,0.00049633003,0.00008792311],"about_ca_topic_score_codex":4.815743e-7,"about_ca_topic_score_gemma":2.7081944e-8,"teacher_disagreement_score":0.021248123,"about_ca_system_score_codex":0.0000073149918,"about_ca_system_score_gemma":0.000023511175,"threshold_uncertainty_score":0.44032326},"labels":[],"label_agreement":null},{"id":"W2138199798","doi":"10.1161/01.hyp.35.1.38","title":"G-Protein–Coupled Receptor Kinase Activity in Hypertension","year":2000,"lang":"en","type":"article","venue":"Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"National Institute of General Medical Sciences; American Heart Association; Medical Research Council; National Institutes of Health; Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Internal medicine; Endocrinology; Medicine; Vascular smooth muscle; Receptor; Lymphocyte; Adenylyl cyclase; Vasodilation; G protein; Protein kinase A; Kinase; Biology","score_opus":0.015759862626697176,"score_gpt":0.21524314587234325,"score_spread":0.19948328324564607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138199798","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982878,0.00041316316,0.00017091788,0.00018510521,0.00016136446,0.00025332198,0.0000037046243,0.000027593134,0.0004970554],"genre_scores_gemma":[0.9965629,0.00031517725,0.0011250409,0.00046077764,0.00019577931,0.000022148766,0.000057861456,0.00003631305,0.0012240284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987158,0.000086956934,0.00019669393,0.00049589697,0.00017918312,0.0003254383],"domain_scores_gemma":[0.9993956,0.000009096902,0.00004351626,0.00037906616,0.00006832344,0.00010438716],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002107571,0.00020458836,0.0002360973,0.000057888206,0.00009950687,0.000021127331,0.0001275949,0.000245464,0.0008293604],"category_scores_gemma":[0.00005365574,0.00017975745,0.000102809965,0.00013574756,0.000031624826,0.000009013003,0.00005138332,0.00014757419,0.00015934142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027753258,0.00013084008,0.000053685537,0.000007237854,0.000007634767,0.000021605454,0.000009860436,0.000076138276,0.97331953,0.0000097772145,0.00081073726,0.025275433],"study_design_scores_gemma":[0.0011073204,0.00030167965,0.0008562355,0.00007128576,0.00000916226,0.000036803296,0.000026162521,0.003478964,0.970448,0.000050241302,0.023293084,0.00032102526],"about_ca_topic_score_codex":0.00016817442,"about_ca_topic_score_gemma":0.000027749671,"teacher_disagreement_score":0.024954408,"about_ca_system_score_codex":0.000019499246,"about_ca_system_score_gemma":0.000036150253,"threshold_uncertainty_score":0.9080914},"labels":[],"label_agreement":null},{"id":"W2138214694","doi":"10.1152/ajplung.2001.280.4.l666","title":"Excitation-contraction coupling in pulmonary vascular smooth muscle involves tyrosine kinase and Rho kinase","year":2001,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Rho-associated protein kinase; Calphostin C; Tyrosine kinase; Chelerythrine; Internal medicine; Endocrinology; Chemistry; Cyclopiazonic acid; Protein kinase C; Biology; Signal transduction; Intracellular; Biochemistry; Medicine","score_opus":0.004928993895962189,"score_gpt":0.22037966450069865,"score_spread":0.21545067060473647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138214694","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988634,0.0076247775,0.0032831745,0.000091044436,0.00017729534,0.00015629458,0.0000036940064,0.0000072799708,0.000022464394],"genre_scores_gemma":[0.9947281,0.003674609,0.0008687517,0.00035578464,0.00024855195,0.000010857903,0.000065557004,0.000039057904,0.000008762522],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982482,0.00022871024,0.0004973336,0.00049542397,0.00013603354,0.00039425926],"domain_scores_gemma":[0.9989321,0.00004893985,0.00043546184,0.00026113677,0.0001542708,0.00016805837],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003631652,0.00029715928,0.00056890614,0.00018896295,0.000107830005,0.00002067498,0.00017126562,0.00016289533,0.000022623346],"category_scores_gemma":[0.00006866746,0.00027732848,0.00018337501,0.00020319964,0.00036743638,0.000027180313,0.000097677315,0.0002952962,0.000001017365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030486952,0.00013609802,0.00037399185,0.000031549338,0.00010015182,0.00005840443,0.000076111646,0.0015973367,0.99398243,0.00010796711,0.000015147001,0.0032159544],"study_design_scores_gemma":[0.0038067542,0.003974861,0.13421097,0.00023042424,0.00028835176,0.0001819149,0.0022527743,0.01101965,0.83446246,0.003408643,0.0048687705,0.0012944114],"about_ca_topic_score_codex":0.00009459327,"about_ca_topic_score_gemma":0.000006877231,"teacher_disagreement_score":0.15951994,"about_ca_system_score_codex":0.000024009572,"about_ca_system_score_gemma":0.00006625493,"threshold_uncertainty_score":0.9999679},"labels":[],"label_agreement":null},{"id":"W2138517493","doi":"10.1016/s0196-9781(00)00265-5","title":"Angiotensin II does not induce apoptosis but rather prevents apoptosis in cardiomyocytes","year":2000,"lang":"en","type":"article","venue":"Peptides","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Sanofi","keywords":"Propidium iodide; Apoptosis; Angiotensin II; Losartan; Endocrinology; Internal medicine; Biology; Receptor; TUNEL assay; Molecular biology; Cell biology; Programmed cell death; Medicine; Biochemistry","score_opus":0.01057197360818005,"score_gpt":0.23056865524065404,"score_spread":0.219996681632474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138517493","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980972,0.0002674318,0.00006338674,0.00016171098,0.0001632074,0.00017832353,0.000021416223,0.000019909563,0.0010274498],"genre_scores_gemma":[0.9917781,0.00033589426,0.0014363669,0.0003010324,0.00032191756,0.000036201334,0.000038406735,0.000034712666,0.0057173786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877024,0.00006543258,0.00024751792,0.00042523403,0.00015754883,0.00033400775],"domain_scores_gemma":[0.9995107,0.000011445351,0.000051061485,0.00031022658,0.000039025697,0.00007754134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021325557,0.00020901464,0.00023283265,0.0000583572,0.00011521847,0.000036894256,0.00019077859,0.00019025775,0.00047538138],"category_scores_gemma":[0.00003393416,0.00016899161,0.00016520014,0.000106649066,0.000041888776,0.000008960188,0.00008124009,0.00010200979,0.000030005845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006125032,0.000059198963,0.00076958945,0.000007402106,0.000052614945,8.290811e-7,0.00013373324,0.000102149555,0.98247534,0.000011456731,0.00055659865,0.015769815],"study_design_scores_gemma":[0.00034973837,0.0001222766,0.0004269771,0.00003539306,0.000017684113,0.0000020763391,0.000102627186,0.00001907699,0.9859492,0.00010211693,0.012620668,0.0002521358],"about_ca_topic_score_codex":0.0002182548,"about_ca_topic_score_gemma":0.000024870369,"teacher_disagreement_score":0.01551768,"about_ca_system_score_codex":0.000019939485,"about_ca_system_score_gemma":0.000031866202,"threshold_uncertainty_score":0.6891278},"labels":[],"label_agreement":null},{"id":"W2138522473","doi":"10.1124/jpet.114.216523","title":"Modulation of Resistance Artery Tone by the Trace Amine β-Phenylethylamine: Dual Indirect Sympathomimetic and α1-Adrenoceptor Blocking Actions","year":2014,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Directorate for Biological Sciences; Faculty of Medicine and Dentistry, University of Alberta; Heart and Stroke Foundation of Canada","keywords":"Chemistry; Rauwolscine; Methoxamine; Vasodilation; Vasoconstriction; Phenylephrine; Hexamethonium; Endocrinology; Internal medicine; Yohimbine; Agonist; Antagonist; Biochemistry; Receptor; Blood pressure; Medicine","score_opus":0.015798535616615754,"score_gpt":0.3046908809504894,"score_spread":0.28889234533387365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138522473","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9880779,0.009633438,0.0016220538,0.00024716978,0.00029730043,0.00007637849,0.0000051282955,0.0000021333133,0.000038491722],"genre_scores_gemma":[0.99813646,0.0006556866,0.00049085304,0.00031391956,0.00025674497,0.0000032799385,0.000003897573,0.000011396936,0.00012776126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999274,0.00014040139,0.0002645944,0.00011320673,0.000093650335,0.00011413411],"domain_scores_gemma":[0.9995539,0.000049591006,0.00024833946,0.000057328554,0.000051838695,0.000038961232],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031345143,0.00010850294,0.00017100014,0.00003339426,0.000116388306,0.0000130579765,0.00006979041,0.00009152057,0.000041986543],"category_scores_gemma":[0.000005751067,0.00008139247,0.000049980932,0.000040737596,0.00012625896,0.000010253633,0.000028053733,0.00012337901,1.420795e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023460957,0.00009050564,0.00009063759,0.0000073296283,0.00014007694,8.36486e-7,0.00039931329,0.00003364649,0.99685824,0.000018371336,0.0003189171,0.0018075322],"study_design_scores_gemma":[0.0009689265,0.0005544059,0.00016989683,0.00000894356,0.000079854486,0.000085565276,0.00041753182,0.00032577803,0.9911767,0.00003891778,0.006088408,0.00008505723],"about_ca_topic_score_codex":5.666682e-7,"about_ca_topic_score_gemma":5.3641776e-7,"teacher_disagreement_score":0.010058554,"about_ca_system_score_codex":0.0000115536795,"about_ca_system_score_gemma":0.000017252061,"threshold_uncertainty_score":0.33190885},"labels":[],"label_agreement":null},{"id":"W2138610759","doi":"10.1124/mol.107.044214","title":"The RGS2 Gene Product from a Candidate Hypertension Allele Shows Decreased Plasma Membrane Association and Inhibition of Gq","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs","funders":"","keywords":"RGS2; Missense mutation; Mutant; Allele; Mutation; Bilayer; Biology; Population; Receptor; Chemistry; Cell biology; Biophysics; Biochemistry; G protein; Gene; Medicine; Membrane; GTPase-activating protein","score_opus":0.008667046327497853,"score_gpt":0.2209787069717483,"score_spread":0.21231166064425044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138610759","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99676037,0.0015578464,0.0007455676,0.0003653857,0.00022201781,0.0002580966,0.000030089343,0.000010196545,0.000050456656],"genre_scores_gemma":[0.9970527,0.001290387,0.00061287667,0.00047001845,0.00016597484,0.000032373377,0.00023972862,0.000020996595,0.00011490979],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988637,0.00019945316,0.00022773197,0.00032573906,0.00015632498,0.00022705134],"domain_scores_gemma":[0.99944,0.000035595505,0.000161654,0.00015634607,0.00013205965,0.00007431562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002374547,0.00014013892,0.00018036537,0.000029108416,0.00018007624,0.000009413011,0.00008746624,0.00013305842,0.00007123148],"category_scores_gemma":[0.00006963982,0.000115732284,0.00006896379,0.000059182825,0.00006647448,0.0000044711737,0.0000762965,0.000096308606,0.0000027821773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019647887,0.000049385504,0.00023902844,0.00000505239,0.00014554769,0.000032562093,0.000037049416,0.00009099104,0.99706244,0.0000102431995,0.0016462369,0.0004849941],"study_design_scores_gemma":[0.0012489967,0.00013771353,0.00020506131,0.000003292564,0.000073229916,0.000033728502,0.000013448835,0.00076148985,0.99173754,0.000051470826,0.0056070006,0.00012700679],"about_ca_topic_score_codex":0.000107365595,"about_ca_topic_score_gemma":0.00002154826,"teacher_disagreement_score":0.00532487,"about_ca_system_score_codex":0.000023294691,"about_ca_system_score_gemma":0.00007015472,"threshold_uncertainty_score":0.47194254},"labels":[],"label_agreement":null},{"id":"W2139097765","doi":"10.5041/rmmj.10078","title":"Novel Strategies for the Treatment of Heart Failure","year":2012,"lang":"en","type":"article","venue":"Rambam Maimonides Medical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Centre for Interdisciplinary Research in Rehabilitation","keywords":"Heart failure; Medicine; Excitation–contraction coupling; Bioinformatics; Receptor; Cardiology; Neuroscience; Internal medicine; Biology; Calcium","score_opus":0.019194705507787492,"score_gpt":0.28721897244314926,"score_spread":0.26802426693536174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139097765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7058954,0.007157619,0.28344017,0.0020719005,0.001028539,0.0002791587,0.0000139631775,0.0000071672566,0.000106083986],"genre_scores_gemma":[0.9887605,0.00061797356,0.008512195,0.00020164413,0.001777903,0.000017567112,0.000007673954,0.000014745321,0.000089840796],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991017,0.000029712612,0.00023473149,0.00009145616,0.00025751407,0.0002848794],"domain_scores_gemma":[0.9994373,0.0000665448,0.00008995901,0.00012955465,0.000067975794,0.00020870964],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046646144,0.000110450484,0.00015162946,0.00001872589,0.00013814631,0.00003614376,0.00015367712,0.00013657882,0.0002769607],"category_scores_gemma":[0.00007721095,0.00006158651,0.00020289705,0.000031751908,0.00007790484,0.000007138943,0.000017302358,0.00008624575,0.0000018547946],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000106588486,0.000394934,0.0010211358,0.000013765681,0.00022019513,8.973408e-7,0.00021869273,0.00007488895,0.97104996,0.0014789326,0.0075809583,0.017839065],"study_design_scores_gemma":[0.0013761166,0.001739547,0.0012588724,0.000047586553,0.000100652884,0.00047743047,0.002699712,0.0002854002,0.42294878,0.00048715755,0.5683777,0.0002010395],"about_ca_topic_score_codex":0.00000844514,"about_ca_topic_score_gemma":0.000011393655,"teacher_disagreement_score":0.56079674,"about_ca_system_score_codex":0.000014709778,"about_ca_system_score_gemma":0.0001709164,"threshold_uncertainty_score":0.30325252},"labels":[],"label_agreement":null},{"id":"W2139286816","doi":"10.1074/jbc.m306019200","title":"Activation-independent Parathyroid Hormone Receptor Internalization Is Regulated by NHERF1 (EBP50)","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Internalization; Parathyroid hormone receptor; Parathyroid hormone; Dynamin; Endocytosis; Cell biology; Endocytic cycle; Receptor; Chemistry; G protein-coupled receptor; Biology; Hormone receptor; Calcium; Biochemistry","score_opus":0.012960158369642613,"score_gpt":0.23600563745387693,"score_spread":0.2230454790842343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139286816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98439026,0.0018726352,0.012883322,0.00008997938,0.00009248304,0.000058694066,0.000011578588,0.0000068870804,0.0005941611],"genre_scores_gemma":[0.9968358,0.00086939527,0.0007674598,0.00025728953,0.00025548463,0.0000029963091,0.000073615265,0.000014914748,0.0009230103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878675,0.00007331575,0.0004815149,0.0002444736,0.00020904861,0.00020491166],"domain_scores_gemma":[0.99901766,0.000016123793,0.0004419148,0.00016131351,0.00022189904,0.0001410644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035790403,0.000181692,0.00022739619,0.000017050836,0.00006167735,0.000035904686,0.0002192165,0.00038728636,0.00079291366],"category_scores_gemma":[0.00024409415,0.00013668573,0.00017535966,0.00008651898,0.000046339457,0.000009014305,0.00003473746,0.00021641799,0.000006212394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014949428,0.000093554474,0.00021208916,0.000004930571,0.00007021974,0.0000021138162,0.000017078639,0.00001773338,0.98234266,0.0000141934315,0.01682331,0.00025263522],"study_design_scores_gemma":[0.00059272064,0.00033786334,0.0000623295,0.000017893482,0.000009894245,0.000060173144,0.00007700312,0.000009121346,0.9467831,0.00019592664,0.051686946,0.00016699346],"about_ca_topic_score_codex":0.0000012992571,"about_ca_topic_score_gemma":4.2509885e-8,"teacher_disagreement_score":0.035559513,"about_ca_system_score_codex":0.000040435913,"about_ca_system_score_gemma":0.00005647521,"threshold_uncertainty_score":0.86818486},"labels":[],"label_agreement":null},{"id":"W2139299435","doi":"10.1124/mol.105.012229","title":"D1 and D2 Dopamine Receptors Form Heterooligomers and Cointernalize after Selective Activation of Either Receptor","year":2005,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse","keywords":"Receptor; Dopamine receptor D2; Dopamine receptor; Dopamine; D2-like receptor; Dopamine receptor D1; Chemistry; D1-like receptor; Neuroscience; Pharmacology; Psychology; Biology; Biochemistry","score_opus":0.004676035901442749,"score_gpt":0.24651932449207614,"score_spread":0.2418432885906334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139299435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938643,0.00072523736,0.00443266,0.00027525303,0.00017745822,0.00024420815,0.000008844412,0.000009768169,0.00026224484],"genre_scores_gemma":[0.99640065,0.00031269607,0.0019337285,0.00079160475,0.00016662492,0.00005198081,0.000025747164,0.00003235566,0.00028462664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899864,0.000093057,0.00022688524,0.000351546,0.00009605985,0.00023378043],"domain_scores_gemma":[0.9995855,0.000013306769,0.00011696572,0.00010588905,0.00008441378,0.00009391668],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014446242,0.00018454027,0.000201841,0.000075207885,0.000038132162,0.0000115067905,0.000082301965,0.00015236631,0.00042282778],"category_scores_gemma":[0.000017615008,0.00017922083,0.00006244324,0.000053490057,0.00010371807,0.00001164175,0.00009586232,0.000105931016,0.0000036041213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038945625,0.000048246122,0.00041045857,0.00002013439,0.00014638645,0.0000020120144,0.00012201665,0.000027451764,0.99087024,0.000042395342,0.0004921437,0.007429068],"study_design_scores_gemma":[0.0010446465,0.00043558492,0.00016682054,0.000012551623,0.00004115012,0.000018619348,0.00003869077,0.00013367407,0.9680602,0.000036242134,0.02983136,0.00018045255],"about_ca_topic_score_codex":0.000014008187,"about_ca_topic_score_gemma":0.000003790921,"teacher_disagreement_score":0.029339215,"about_ca_system_score_codex":0.000023389102,"about_ca_system_score_gemma":0.000022671766,"threshold_uncertainty_score":0.73084134},"labels":[],"label_agreement":null},{"id":"W2139364634","doi":"10.1124/mol.109.055509","title":"Agonist-Biased Signaling via Proteinase Activated Receptor-2: Differential Activation of Calcium and Mitogen-Activated Protein Kinase Pathways","year":2009,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; University of Calgary","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; Canadian Association of Gastroenterology","keywords":"Agonist; Receptor; Protein kinase A; Signal transduction; Kinase; Biology; Molecular biology; Stereochemistry; Biochemistry; Chemistry","score_opus":0.014341586345342628,"score_gpt":0.25809703719898835,"score_spread":0.24375545085364572,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139364634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9611754,0.00018161631,0.037008848,0.0001971348,0.00022260545,0.001107516,0.00002311434,0.00004176345,0.000041994255],"genre_scores_gemma":[0.99772674,0.000014156484,0.0012436309,0.00031055318,0.00019248025,0.00011518089,0.0002898947,0.000047955953,0.000059436486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793,0.00032967026,0.00043502075,0.0006294336,0.00022465736,0.00045121324],"domain_scores_gemma":[0.9990405,0.000014815603,0.0003048214,0.00025656767,0.00019800261,0.00018529141],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018262393,0.00036603864,0.00037556107,0.00013018386,0.00014983526,0.00002739175,0.00020798942,0.000359407,0.00031436404],"category_scores_gemma":[0.000057198682,0.0003733913,0.0001485989,0.00020033478,0.00009649469,0.000015586234,0.00008772288,0.00024904942,0.0000027989977],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010713474,0.00026543686,0.0000051898755,0.00004625903,0.00014120579,0.000016984153,0.00007743608,0.0001023314,0.99303293,0.000085667314,0.00008822593,0.0050670058],"study_design_scores_gemma":[0.0021928072,0.0010969557,0.000025363153,0.000040220144,0.000058001588,0.000007918582,0.00003111954,0.00026271158,0.9949204,0.00015382466,0.0008262819,0.00038442557],"about_ca_topic_score_codex":0.000025636515,"about_ca_topic_score_gemma":3.8522177e-7,"teacher_disagreement_score":0.036551304,"about_ca_system_score_codex":0.000039229268,"about_ca_system_score_gemma":0.00010537653,"threshold_uncertainty_score":0.9998718},"labels":[],"label_agreement":null},{"id":"W2139926908","doi":"10.1177/1087057106298287","title":"Using Ligand-Induced Conformational Change to Screen for Compounds Targeting G-Protein-Coupled Receptors","year":2007,"lang":"en","type":"article","venue":"SLAS DISCOVERY","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canada Research Chairs","keywords":"G protein-coupled receptor; Receptor; Agonist; Ligand (biochemistry); Drug discovery; Inverse agonist; Chemistry; Biochemistry; Cell biology; Biology; Biophysics","score_opus":0.049380499505690595,"score_gpt":0.303273219937241,"score_spread":0.2538927204315504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139926908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8414653,0.00009636094,0.15709905,0.000048876762,0.00043849586,0.0005795235,0.000033407814,0.000014372063,0.00022460395],"genre_scores_gemma":[0.98586226,0.0000048075476,0.011895209,0.00047484454,0.0011182429,0.000042103537,0.000357127,0.000034899975,0.00021050738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987988,0.000015489868,0.00031085443,0.00029137637,0.00018512616,0.00039838656],"domain_scores_gemma":[0.99946815,0.00001954534,0.00011823373,0.00016247273,0.000116597155,0.00011501903],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058969704,0.00018231277,0.00017242783,0.00007692086,0.0001938755,0.00009023327,0.00015715307,0.00015057491,0.00002387488],"category_scores_gemma":[0.0000837761,0.00017741819,0.00013195824,0.00010269554,0.000017873952,0.0000329352,0.00008959848,0.000068970956,0.0000075860867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001780565,0.000020677926,0.00014434467,0.000017168235,0.000034672066,5.589267e-7,0.000106637446,0.000049749,0.9977139,0.00096596306,0.00026773152,0.0005005281],"study_design_scores_gemma":[0.00053992734,0.00027537099,0.000103922845,0.0000435497,0.000012233562,0.0000029200646,0.00033159865,0.0008484126,0.9903552,0.0001481899,0.007050561,0.00028812396],"about_ca_topic_score_codex":0.000078768455,"about_ca_topic_score_gemma":0.000028858585,"teacher_disagreement_score":0.14520384,"about_ca_system_score_codex":0.00003863532,"about_ca_system_score_gemma":0.000063834654,"threshold_uncertainty_score":0.72349036},"labels":[],"label_agreement":null},{"id":"W2139953951","doi":"10.1124/mol.62.3.654","title":"Characterization and Comparison of RGS2 and RGS4 as GTPase-Activating Proteins for m2 Muscarinic Receptor-Stimulated Gi","year":2002,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"RGS2; Regulator of G protein signaling; G protein; GTPase-activating protein; Muscarinic acetylcholine receptor; GTPase; Biophysics; Biology; Carbachol; Cell biology; GTP'; Chemistry; Molecular biology; Biochemistry; Receptor","score_opus":0.02050622333406117,"score_gpt":0.29827134178989223,"score_spread":0.2777651184558311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139953951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9660528,0.00075284677,0.032120157,0.00016172344,0.00016521479,0.00065527024,0.000020338373,0.000014522229,0.00005715182],"genre_scores_gemma":[0.9963596,0.00014224305,0.00273814,0.00026345198,0.00009401999,0.00008925825,0.00015980993,0.000033082662,0.000120410165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893427,0.00009957095,0.0002920958,0.00036362713,0.00008208806,0.00022832387],"domain_scores_gemma":[0.9994909,0.000022173565,0.00018883208,0.000112947506,0.00009994841,0.00008520107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014124437,0.00017061442,0.0002563786,0.000057823774,0.00009490589,0.000016414877,0.00008520034,0.00020748774,0.00023796537],"category_scores_gemma":[0.00005865935,0.0001812343,0.000056599438,0.00007418188,0.000070664384,0.000007215413,0.000083006795,0.00010398783,0.0000019552958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011013553,0.00008766291,0.00027577588,0.000060346087,0.000091884554,0.0000014621365,0.0001448803,0.000062833744,0.9893735,0.00007053385,0.000099212826,0.009621757],"study_design_scores_gemma":[0.0012632732,0.00073522597,0.00011973467,0.0000142762565,0.000044113272,0.0000074685154,0.000031544616,0.0075957426,0.98237646,0.000024663103,0.0076048896,0.00018260743],"about_ca_topic_score_codex":0.000009735879,"about_ca_topic_score_gemma":9.640422e-7,"teacher_disagreement_score":0.030306807,"about_ca_system_score_codex":0.000008966708,"about_ca_system_score_gemma":0.000013984521,"threshold_uncertainty_score":0.739052},"labels":[],"label_agreement":null},{"id":"W2140663833","doi":"10.1124/mol.114.093294","title":"Complex Pharmacology of Novel Allosteric Free Fatty Acid 3 Receptor Ligands","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Allosteric regulation; Chemistry; Biochemistry; Pharmacology; Receptor; Stereochemistry; Computational biology; Biology","score_opus":0.017822756226214733,"score_gpt":0.2807837400377126,"score_spread":0.2629609838114979,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140663833","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89584386,0.00046992593,0.099896856,0.00061167445,0.0016899229,0.00037455367,0.00006212149,0.000036337427,0.0010147669],"genre_scores_gemma":[0.9848385,0.00010348923,0.010208697,0.0037222682,0.0006649899,0.0000711961,0.00020624675,0.00006649683,0.000118108386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979822,0.00019296247,0.00048150925,0.0006050502,0.00020436519,0.0005339263],"domain_scores_gemma":[0.9989197,0.000028746512,0.00025373482,0.00042103702,0.00018471935,0.00019205468],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00040152352,0.0003295886,0.00045075052,0.00011459033,0.00009246748,0.000012955957,0.0007069553,0.0003084724,0.0017897115],"category_scores_gemma":[0.000054774122,0.00034075466,0.00023319217,0.00017203853,0.0001905144,0.0000060028983,0.00043955192,0.00020162275,0.000026081409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002287377,0.00026443336,0.00005207153,0.00004178898,0.0002490394,0.000005279926,0.00003806642,0.00028689986,0.9822537,0.0002443807,0.015329027,0.0010066332],"study_design_scores_gemma":[0.00343173,0.00075838267,0.000047811744,0.000006071275,0.0001079814,0.000025384901,0.00001573016,0.0010731827,0.9263549,0.00005152313,0.06780727,0.00032006495],"about_ca_topic_score_codex":0.000009621095,"about_ca_topic_score_gemma":0.0000018924052,"teacher_disagreement_score":0.08968816,"about_ca_system_score_codex":0.000021767202,"about_ca_system_score_gemma":0.00007075388,"threshold_uncertainty_score":0.99990445},"labels":[],"label_agreement":null},{"id":"W2141673227","doi":"10.1016/j.pnpbp.2004.11.004","title":"On the trail of a cognitive enhancer for the treatment of schizophrenia","year":2005,"lang":"en","type":"review","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Royal Ottawa Mental Health Centre; University of Ottawa; Hôpital Louis-H Lafontaine; Université de Montréal","funders":"","keywords":"Schizophrenia (object-oriented programming); Psychology; Cholinergic; Prefrontal cortex; Cognition; Neuroscience; Dopamine; Risperidone; Cognitive deficit; Acetylcholine; Pharmacology; Medicine; Psychiatry; Cognitive impairment","score_opus":0.04985206363932502,"score_gpt":0.3792070277366273,"score_spread":0.32935496409730225,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141673227","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.048298575,0.94833297,0.000037654805,0.00023072361,0.0009351994,0.0019778416,0.00015173029,0.0000053345807,0.000030000969],"genre_scores_gemma":[0.03100781,0.9667397,0.00015849668,0.00028051483,0.0005613506,0.0011616524,0.00004862438,0.00002344938,0.000018384953],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998179,0.00032827532,0.00057884306,0.0005623446,0.00007525843,0.00027625114],"domain_scores_gemma":[0.9983167,0.000954581,0.00042660558,0.00021060432,0.000046630335,0.000044852815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002723315,0.00038760607,0.0008122507,0.0000625974,0.00009945276,0.000007863731,0.00032930082,0.0004896628,0.000098211254],"category_scores_gemma":[0.000053968946,0.00017287258,0.00047330384,0.00013609823,0.000517008,0.0000016615643,0.00004058276,0.0002422216,0.0000012355248],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0022829312,0.0009781409,0.0002797139,0.00039712465,0.00041686613,9.384779e-7,0.000027249216,8.232138e-7,0.00013457985,0.0007488771,0.000285832,0.99444693],"study_design_scores_gemma":[0.00754732,0.01587915,0.00082588306,0.0021523337,0.001354089,0.000035198675,0.00008926672,0.00002358671,0.0008197182,0.0012293922,0.9692854,0.0007586078],"about_ca_topic_score_codex":5.168097e-7,"about_ca_topic_score_gemma":0.000003226349,"teacher_disagreement_score":0.99368834,"about_ca_system_score_codex":0.000007089071,"about_ca_system_score_gemma":0.000084808424,"threshold_uncertainty_score":0.7049539},"labels":[],"label_agreement":null},{"id":"W2141719987","doi":"10.1109/tnb.2004.833681","title":"Dynamic Ion Channel Activation Scheduling in Patch Clamp on a Chip","year":2004,"lang":"en","type":"article","venue":"IEEE Transactions on NanoBioscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Australian National University","keywords":"Computer science; Scheduling (production processes); Chip; Ion channel; Patch clamp; Nanotechnology; Parallel computing; Materials science; Chemistry; Engineering; Telecommunications","score_opus":0.010845847369960967,"score_gpt":0.24255708532888776,"score_spread":0.23171123795892679,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141719987","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6297042,0.000008738298,0.36962548,0.00013911157,0.00033279022,0.00012669581,0.000004451253,0.000013469685,0.000045082932],"genre_scores_gemma":[0.99817556,0.00007253121,0.0013009843,0.00027543755,0.000027455513,0.000033442506,0.0000057352677,0.000014936831,0.000093935676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998915,0.000029527873,0.00017227718,0.00043630978,0.0001852035,0.00026166515],"domain_scores_gemma":[0.99963003,0.000009941526,0.00005306866,0.00021350992,0.000031782096,0.00006165709],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018853784,0.00014765051,0.00009992469,0.00014943037,0.00018514573,0.000030202598,0.0001666022,0.0001421587,0.000015173627],"category_scores_gemma":[0.000010214448,0.0001419501,0.000071744245,0.00033263818,0.00004959334,0.000015042954,0.0000016404994,0.00016052385,0.00001554787],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052147454,0.00013425264,0.0000025943689,0.0000041218036,0.0000027646106,8.6302265e-7,0.0000776169,0.11599848,0.88188785,0.000037958198,5.8712453e-7,0.0018007458],"study_design_scores_gemma":[0.0005458704,0.00043429996,0.000100488745,0.00008707812,0.000002700381,0.0000040093587,0.00010119506,0.0031540066,0.9951325,0.0002319447,0.000035541005,0.00017037774],"about_ca_topic_score_codex":0.00006833634,"about_ca_topic_score_gemma":0.00010479674,"teacher_disagreement_score":0.36847138,"about_ca_system_score_codex":0.00008753226,"about_ca_system_score_gemma":0.000091137474,"threshold_uncertainty_score":0.57885575},"labels":[],"label_agreement":null},{"id":"W2142067008","doi":"10.1161/circulationaha.111.027268","title":"Response to Letter Regarding Article, “The sPLA <sub>2</sub> Inhibition to Decrease Enzyme Release After Percutaneous Coronary Intervention (SPIDER-PCI) Trial”","year":2011,"lang":"en","type":"article","venue":"Circulation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; Southlake Regional Health Center; University of Toronto; London Health Sciences Centre; University Health Network","funders":"Anthera","keywords":"Medicine; Conventional PCI; Percutaneous coronary intervention; Enzyme inhibition; Enzyme; Cardiology; Internal medicine; Biochemistry; Myocardial infarction","score_opus":0.016202721868378463,"score_gpt":0.23206615702739783,"score_spread":0.21586343515901937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142067008","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9696344,0.00007392591,0.028809141,0.00039612578,0.00029979163,0.0007131232,0.0000069474786,0.00002644856,0.00004009208],"genre_scores_gemma":[0.99627566,0.00000449655,0.0005693194,0.0025840686,0.00031292185,0.00012548527,0.000052292296,0.000035019162,0.000040723644],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850273,0.00031263195,0.00034313722,0.0004116578,0.00018349545,0.000246343],"domain_scores_gemma":[0.9991723,0.00002640942,0.00009078165,0.0003650332,0.00010879562,0.00023669892],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070242555,0.00016763866,0.00012504651,0.00009172997,0.00013068561,0.000051228806,0.00008781845,0.0001433772,0.00017259354],"category_scores_gemma":[0.0005195214,0.00015330558,0.00016120076,0.00013131685,0.000021770673,0.000018506757,0.00007488716,0.00009028035,0.00010403854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.02225072,0.000083863095,0.00019438249,0.000007581924,0.00001961176,0.00004856025,0.00032514508,0.00029028978,0.9713138,0.000021579604,0.0005864793,0.004858008],"study_design_scores_gemma":[0.0027336995,0.00064840773,0.005149598,0.000084269974,0.000045619156,0.00016010573,0.000102862476,0.0002549629,0.9888083,0.00021698921,0.0015183403,0.0002768888],"about_ca_topic_score_codex":0.000017541994,"about_ca_topic_score_gemma":0.000019982312,"teacher_disagreement_score":0.028239822,"about_ca_system_score_codex":0.00006125025,"about_ca_system_score_gemma":0.00003729767,"threshold_uncertainty_score":0.625162},"labels":[],"label_agreement":null},{"id":"W2142551442","doi":"10.1096/fj.03-0648fje","title":"Loss of vagally mediated bradycardia and bronchoconstriction in mice lacking M <sub>2</sub> or M <sub>3</sub> muscarinic acetylcholine receptors","year":2004,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":125,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Muscarinic acetylcholine receptor; Bronchoconstriction; Methacholine; Bradycardia; Medicine; Acetylcholine; Internal medicine; Endocrinology; Muscarinic acetylcholine receptor M3; Vagus nerve; Agonist; In vivo; Heart rate; Stimulation; Receptor; Lung; Asthma; Biology; Respiratory disease; Blood pressure","score_opus":0.009835929669962483,"score_gpt":0.22441947356581968,"score_spread":0.21458354389585718,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142551442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995769,0.00087332394,0.002504557,0.00013981451,0.0004572402,0.0001857053,0.000013226077,0.000009945975,0.00004716363],"genre_scores_gemma":[0.9946705,0.0044232705,0.000289666,0.00013123265,0.00041070863,0.0000056178756,0.000029966688,0.000031803764,0.000007248293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843615,0.00017892355,0.0005120764,0.0002737922,0.00025085825,0.00034818047],"domain_scores_gemma":[0.9991634,0.000054945154,0.00032261782,0.00019060212,0.00012667004,0.00014177778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00086023204,0.00021998516,0.00028139117,0.00012617318,0.00015990055,0.000052962157,0.00022558398,0.00022274001,0.000016396862],"category_scores_gemma":[0.00018203555,0.00016178556,0.00014324176,0.00025540168,0.00012150064,0.00002090082,0.00009894868,0.00043077202,0.0000048970905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021690947,0.000049070182,0.0008806913,0.000014140228,0.00008435572,0.000015004715,0.0002073337,0.0011630747,0.9898221,0.000016498607,0.000055778015,0.007475076],"study_design_scores_gemma":[0.0018459285,0.00027277117,0.00075971324,0.00010303394,0.000042317355,0.00038882715,0.0003039372,0.000051650753,0.9957853,0.00013388821,0.000118809294,0.00019383845],"about_ca_topic_score_codex":0.000017387485,"about_ca_topic_score_gemma":0.00007682947,"teacher_disagreement_score":0.0072812373,"about_ca_system_score_codex":0.00006354209,"about_ca_system_score_gemma":0.00022829574,"threshold_uncertainty_score":0.65974236},"labels":[],"label_agreement":null},{"id":"W2142977626","doi":"10.1093/hmg/ddm277","title":"Genetic determinants of emotionality and stress response in AcB/BcA recombinant congenic mice and in silico evidence of convergence with cardiovascular candidate genes","year":2007,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Aegera Therapeutics (Canada); Centre Hospitalier de l’Université de Montréal","funders":"McGill University Health Centre","keywords":"Congenic; Biology; Candidate gene; Quantitative trait locus; Genetics; Locus (genetics); Gene; In silico; Genetic linkage","score_opus":0.01477541765872497,"score_gpt":0.26864324485317104,"score_spread":0.25386782719444606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142977626","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97461087,0.023335151,0.0017005677,0.000003894897,0.000038501657,0.00029289335,0.000012492129,0.00000213983,0.0000034937502],"genre_scores_gemma":[0.9958068,0.0024358232,0.0016843069,0.000014467728,0.000011903298,0.000008191351,0.0000063688194,0.000023106339,0.000008997044],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99827296,0.00024903932,0.00050099404,0.00045922276,0.0002437998,0.0002740103],"domain_scores_gemma":[0.9991808,0.00003851666,0.0001599229,0.00041058756,0.00012333614,0.00008686316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010090971,0.00019795362,0.0003722662,0.00012328157,0.00003613106,0.000010487809,0.0001670707,0.00014880968,0.000006592766],"category_scores_gemma":[0.00006183118,0.00019686304,0.00007380814,0.00014169063,0.0002106721,0.000005570588,0.00012911767,0.00008311598,1.354697e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067518774,0.000044846805,0.1641729,0.0001355907,0.00005088518,0.000056183595,0.000118429496,0.00080546335,0.8326,0.000006523539,3.08406e-7,0.0013336564],"study_design_scores_gemma":[0.0006374786,0.0005721167,0.37497193,0.00018195678,0.000036013582,0.000028308106,0.00008632551,0.00014175099,0.6231174,0.000045214263,0.000014791657,0.00016671079],"about_ca_topic_score_codex":0.00022206795,"about_ca_topic_score_gemma":0.0010433189,"teacher_disagreement_score":0.21079902,"about_ca_system_score_codex":0.00001614276,"about_ca_system_score_gemma":0.0000847647,"threshold_uncertainty_score":0.80278414},"labels":[],"label_agreement":null},{"id":"W2143166807","doi":"10.1073/pnas.220414397","title":"Regulation of T cell activation, anxiety, and male aggression by RGS2","year":2000,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":282,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; Ontario Institute for Cancer Research","funders":"National Institute on Alcohol Abuse and Alcoholism","keywords":"RGS2; Biology; Cell biology; G protein; GTPase; Aggression; Signal transduction; Neuroscience; GTPase-activating protein; Psychology; Psychiatry","score_opus":0.012162207652235814,"score_gpt":0.251724037121875,"score_spread":0.23956182946963922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143166807","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962217,0.0002136506,0.0000056403546,0.00024247493,0.000004194094,0.000061356535,0.0000057135035,0.0000010979827,0.0032441563],"genre_scores_gemma":[0.9979711,0.00027960588,0.001035005,0.000052915868,0.000028517139,0.0000017303671,7.165328e-7,0.0000019988595,0.0006284027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993466,0.0000034812422,0.00014839674,0.00012901198,0.0003180312,0.000054460816],"domain_scores_gemma":[0.9996608,0.000007787786,0.00020574634,0.0000050365234,0.00010678964,0.000013858512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035845157,0.000043346477,0.000058072026,0.000026542059,0.000073538235,0.0000059996196,0.00016859261,0.00006711707,0.00008706983],"category_scores_gemma":[0.000043196447,0.0000307775,0.00002615841,0.00013464235,0.0001744287,0.000019139936,0.000035205292,0.000032899537,1.3787727e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013010413,0.000014362268,0.0014288306,0.000018319293,0.0000023335933,8.272764e-11,0.00002778789,0.00003942774,0.99568164,0.00042156054,0.00095407636,0.0013986414],"study_design_scores_gemma":[0.00009255025,0.000037617854,0.004321154,0.00005079307,0.0000026029054,0.0000016244769,0.00003228608,0.00020419486,0.99164677,0.0029208506,0.00065477524,0.000034795663],"about_ca_topic_score_codex":0.0000022028287,"about_ca_topic_score_gemma":6.7012356e-9,"teacher_disagreement_score":0.004034895,"about_ca_system_score_codex":0.0000031867671,"about_ca_system_score_gemma":0.000009798878,"threshold_uncertainty_score":0.12550701},"labels":[],"label_agreement":null},{"id":"W2143544378","doi":"10.1146/annurev-pharmtox-061008-103038","title":"The Role of Gβγ Subunits in the Organization, Assembly, and Function of GPCR Signaling Complexes","year":2008,"lang":"en","type":"review","venue":"The Annual Review of Pharmacology and Toxicology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":269,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Dalhousie University","funders":"National Institutes of Health","keywords":"Effector; G protein-coupled receptor; Cell biology; Signal transduction; Receptor; Cell signaling; G protein; Protein subunit; Biology; Chemistry; Function (biology); Biochemistry; Gene","score_opus":0.01593686437129242,"score_gpt":0.3121301754907215,"score_spread":0.29619331111942904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2143544378","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.006008554,0.99286085,0.000032345084,0.00013697408,0.00013783078,0.0007061623,0.0000368041,0.0000019637741,0.00007850816],"genre_scores_gemma":[0.01949323,0.9798573,0.0000156313,0.00038374495,0.00010954515,0.00004124768,0.000065563705,0.000016726928,0.000016980106],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997495,0.0012586041,0.0007335559,0.00022404394,0.00010365964,0.00018514512],"domain_scores_gemma":[0.9982981,0.00051947584,0.00071045087,0.00019736399,0.0002506874,0.000023895476],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011627218,0.0002195274,0.000903445,0.000050513616,0.00016907063,0.0000040956998,0.0004055871,0.00024587684,0.000043384112],"category_scores_gemma":[0.00018121494,0.00011183496,0.00012736156,0.00027429374,0.00043123157,0.000005562998,0.00016925827,0.0002466536,7.203154e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014885854,0.0003119127,0.00008391801,0.026619054,0.0011367266,0.0000051997154,0.00076061446,0.000008449673,0.17400905,0.006233683,0.005513822,0.7851687],"study_design_scores_gemma":[0.00025538082,0.0005672132,0.000025499667,0.0020437764,0.0007543443,0.00012989105,0.0002993246,0.0000021935014,0.017397227,0.00019636315,0.9781819,0.00014691471],"about_ca_topic_score_codex":0.000009241169,"about_ca_topic_score_gemma":0.0000074928175,"teacher_disagreement_score":0.97266805,"about_ca_system_score_codex":0.000005541105,"about_ca_system_score_gemma":0.00016306348,"threshold_uncertainty_score":0.45604974},"labels":[],"label_agreement":null},{"id":"W2144254021","doi":"10.1177/1087057108324032","title":"Demonstration of Improvements to the Bioluminescence Resonance Energy Transfer (BRET) Technology for the Monitoring of G Protein–Coupled Receptors in Live Cells","year":2008,"lang":"en","type":"article","venue":"SLAS DISCOVERY","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Health and Medical Research Council; RIKEN Brain Science Institute; RIKEN; Medical Research Council; Université de Montréal","keywords":"Bioluminescence; Luciferase; G protein-coupled receptor; Receptor; Luciferases; Biophysics; Chemistry; Energy transfer; Resonance (particle physics); Ligand (biochemistry); Protein–protein interaction; Cell biology; Biology; Biochemistry; Physics; Transfection; Chemical physics","score_opus":0.010242435849909038,"score_gpt":0.22014493532248938,"score_spread":0.20990249947258036,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144254021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9516317,0.0010744854,0.046479385,0.00009028604,0.00020154253,0.0004932492,0.000015989444,0.0000031071904,0.000010213413],"genre_scores_gemma":[0.9982955,0.00043010907,0.0006827474,0.000018178982,0.0000876321,0.00018979581,0.000006468435,0.000011966326,0.00027760467],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999253,0.000022047712,0.00025228912,0.00020764278,0.000103295504,0.0001617754],"domain_scores_gemma":[0.99959815,0.00002054101,0.00006339147,0.00023140974,0.00007162922,0.000014861641],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014241648,0.00010222722,0.00012688614,0.000041875814,0.000057981673,0.0000063324987,0.00023539581,0.000104919345,0.000002977588],"category_scores_gemma":[0.00003195405,0.00006708046,0.000071265866,0.00016485907,0.00008771161,0.000008840803,0.000038677503,0.000050581868,2.8554524e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011299083,0.000035138317,0.0012828369,0.000013198974,0.000016418342,2.1107377e-7,0.0001065273,0.00014493347,0.99556845,0.0005592172,0.000022018114,0.002138057],"study_design_scores_gemma":[0.00025636406,0.00033505514,0.00020487474,0.00005343034,0.0000064397036,7.205805e-7,0.00038909412,0.00013332865,0.9976179,0.00007782459,0.0008466559,0.000078327976],"about_ca_topic_score_codex":0.00012804141,"about_ca_topic_score_gemma":0.00007770185,"teacher_disagreement_score":0.046663757,"about_ca_system_score_codex":0.000010889006,"about_ca_system_score_gemma":0.000064304666,"threshold_uncertainty_score":0.2735462},"labels":[],"label_agreement":null},{"id":"W2144677370","doi":"10.1002/syn.20210","title":"Dopamine agonist action of phencyclidine","year":2005,"lang":"en","type":"article","venue":"Synapse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Phencyclidine; Psychotomimetic; Dopamine; Agonist; Pharmacology; Dopamine agonist; Dopamine receptor; Neuroscience; Chemistry; Psychology; Dopaminergic; Receptor; Internal medicine; Medicine; NMDA receptor","score_opus":0.014421546460090948,"score_gpt":0.2660395952658488,"score_spread":0.25161804880575783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144677370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944369,0.00037216357,0.003151227,0.00012820153,0.00010842592,0.0000549237,0.000005997677,0.0000076088313,0.0017345367],"genre_scores_gemma":[0.9968084,0.00013831744,0.0014594424,0.000043426317,0.00031812603,0.0000044100025,0.000046710604,0.000009314279,0.0011718381],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999554,0.000015799109,0.00012794146,0.00013551283,0.00006375866,0.00010303298],"domain_scores_gemma":[0.99972254,0.0000030746794,0.00005594387,0.0001511936,0.000034729717,0.000032514326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007219661,0.00006730213,0.000079043064,0.000018688923,0.000030486875,0.000004952246,0.00007149952,0.00006782058,0.00026465225],"category_scores_gemma":[0.000022848148,0.00006139728,0.000054588316,0.000035929606,0.000022117318,0.0000022795373,0.00002685059,0.00003386886,0.000014333005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026301444,0.000034172055,0.0000808925,0.0000071101485,0.000014324288,4.921957e-7,0.000010572703,0.000060414382,0.99064654,0.00017432155,0.00044349334,0.008501354],"study_design_scores_gemma":[0.00019237206,0.00013040754,0.000079332036,0.000004681831,0.0000069210896,0.000008518704,0.00003186669,0.00006750381,0.9658405,0.00004235555,0.03352577,0.00006976576],"about_ca_topic_score_codex":0.000009478236,"about_ca_topic_score_gemma":0.0000151223585,"teacher_disagreement_score":0.033082277,"about_ca_system_score_codex":0.0000061682285,"about_ca_system_score_gemma":0.000016364307,"threshold_uncertainty_score":0.28977564},"labels":[],"label_agreement":null},{"id":"W2144799280","doi":"10.1124/mol.113.088880","title":"Quantification of Ligand Bias for Clinically Relevant β2-Adrenergic Receptor Ligands: Implications for Drug Taxonomy","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":233,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Functional selectivity; Receptor; Signal transduction; Effector; Ligand (biochemistry); Drug discovery; Biology; Computational biology; G protein-coupled receptor; Chemistry; Cell biology; Biochemistry","score_opus":0.044760056363428155,"score_gpt":0.3180297258884246,"score_spread":0.27326966952499643,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144799280","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7503642,0.0006288273,0.24467368,0.0014614151,0.00052003283,0.00215407,0.000102948565,0.000019684552,0.00007512588],"genre_scores_gemma":[0.9727203,0.00026035783,0.021621056,0.00081893994,0.0003035383,0.0032761628,0.0005488016,0.000051208186,0.00039958977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983631,0.00007070531,0.000646991,0.000520129,0.00006697726,0.0003321196],"domain_scores_gemma":[0.9985783,0.0001265896,0.00036581917,0.00032919328,0.0004793444,0.0001207402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004781905,0.0001992531,0.0002993133,0.00007297345,0.000111552974,0.000023260778,0.00030586802,0.00021079773,0.00010411321],"category_scores_gemma":[0.00016693716,0.00019582854,0.0002865925,0.00009698044,0.00008532713,0.0000077716895,0.00006555103,0.00007707226,0.000012316162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013347136,0.00013410095,0.00011422522,0.000047500533,0.00013342321,1.0513188e-7,0.000016258624,0.00023206533,0.9755237,0.0011013552,0.019262685,0.0033010761],"study_design_scores_gemma":[0.0012299878,0.00043920169,0.000058495178,0.000008398688,0.000088186505,0.0000023698508,0.000030077133,0.00050144485,0.9261895,0.0008541436,0.07039043,0.00020777035],"about_ca_topic_score_codex":0.000013847621,"about_ca_topic_score_gemma":0.0000021702058,"teacher_disagreement_score":0.22305262,"about_ca_system_score_codex":0.000014948063,"about_ca_system_score_gemma":0.00012528818,"threshold_uncertainty_score":0.7985656},"labels":[],"label_agreement":null},{"id":"W2145740217","doi":"10.1038/pr.2014.183","title":"Adrenergic receptor genotype influences heart failure severity and β-blocker response in children with dilated cardiomyopathy","year":2014,"lang":"en","type":"article","venue":"Pediatric Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Center for Research Resources; National Heart, Lung, and Blood Institute; National Institutes of Health; Hospital for Sick Children; American Heart Association","keywords":"Medicine; Dilated cardiomyopathy; Internal medicine; Cardiology; Heart failure; Ejection fraction; Cardiomyopathy; Beta blocker; Genotype; Hemodynamics; Cohort; Vascular resistance","score_opus":0.010726966176314526,"score_gpt":0.2697613649786542,"score_spread":0.2590343988023397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145740217","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983092,0.0010353425,0.000123819,0.00017350781,0.000029716099,0.00026607435,0.000009113414,0.000012302461,0.00004092275],"genre_scores_gemma":[0.99723095,0.00038563556,0.0017223277,0.000038423783,0.00042814508,0.000038079605,0.000035518235,0.00002482338,0.0000961255],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9977126,0.00072914193,0.00018981037,0.0005102486,0.0004004138,0.00045775014],"domain_scores_gemma":[0.9992435,0.00007096552,0.00003802597,0.00031409983,0.00017762168,0.00015581607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002347333,0.00015534788,0.00019467677,0.00021927754,0.00015507413,0.00006731639,0.0001989373,0.00019612307,0.000048498103],"category_scores_gemma":[0.0003114481,0.00012643384,0.00003953484,0.00051722623,0.00009355407,0.000009153995,0.00017068116,0.00030645897,0.00001662539],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00092985394,0.000035880134,0.7533597,0.0000151966115,0.000026210213,0.0000015753837,0.00007347667,0.00013208608,0.24389806,0.00001626538,0.0010590762,0.00045266922],"study_design_scores_gemma":[0.0016631682,0.0019499426,0.8886828,0.000017303993,0.000025300049,0.000050842824,0.00012133332,0.00019557423,0.09557455,0.00012750749,0.011049453,0.0005422495],"about_ca_topic_score_codex":0.00020125232,"about_ca_topic_score_gemma":0.000034762852,"teacher_disagreement_score":0.1483235,"about_ca_system_score_codex":0.000019413601,"about_ca_system_score_gemma":0.00015115888,"threshold_uncertainty_score":0.5155822},"labels":[],"label_agreement":null},{"id":"W2145941856","doi":"10.1161/01.cir.103.8.1042","title":"Adrenergic Receptor Polymorphisms and Cardiac Function (and Dysfunction)","year":2001,"lang":"en","type":"editorial","venue":"Circulation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Medicine; Heart failure; Receptor; Internal medicine; Disease; Single-nucleotide polymorphism; Diabetes mellitus; Endocrinology; Cardiology; Bioinformatics; Genetics; Biology; Genotype; Gene","score_opus":0.00574192812425378,"score_gpt":0.20744484102412383,"score_spread":0.20170291289987005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145941856","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.18669824,0.009336154,0.0095283445,0.000032602533,0.7935038,0.00035180262,0.00008772472,0.00004872602,0.00041259325],"genre_scores_gemma":[0.23785321,0.003082473,0.00023798112,0.00003194333,0.75101364,0.0000538153,0.0059013125,0.00009427288,0.0017313577],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986879,0.00007212583,0.00022688984,0.0005670587,0.00025774137,0.00018823572],"domain_scores_gemma":[0.999358,0.000027191676,0.00015515643,0.00022980782,0.00013683608,0.0000930311],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022144079,0.0002530439,0.00023829388,0.00007654781,0.00015517556,0.00007488885,0.000054200194,0.00091448426,0.00010700628],"category_scores_gemma":[0.000103051556,0.0002672826,0.00009107241,0.00007214428,0.000041593095,0.000009112664,0.00005397419,0.00019394903,0.000010744737],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013457134,0.0000194198,0.0015521852,0.000056124725,0.00016639588,5.553576e-7,0.000024848536,0.00012074046,0.66504896,0.00020525971,0.32162014,0.011050811],"study_design_scores_gemma":[0.00057706045,0.00015808028,0.0022449726,0.000046365785,0.00014843322,0.000002231249,0.000019694899,0.000079665966,0.003605712,0.00032864563,0.9923561,0.00043304343],"about_ca_topic_score_codex":0.000041780582,"about_ca_topic_score_gemma":0.0000033925223,"teacher_disagreement_score":0.67073596,"about_ca_system_score_codex":0.000031030228,"about_ca_system_score_gemma":0.00007227851,"threshold_uncertainty_score":0.99997795},"labels":[],"label_agreement":null},{"id":"W2146099270","doi":"10.1371/journal.pcbi.1000975","title":"Scalable Rule-Based Modelling of Allosteric Proteins and Biochemical Networks","year":2010,"lang":"en","type":"article","venue":"PLoS Computational Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Allosteric regulation; Cooperativity; Executable; Computational biology; Modularity (biology); Computer science; Modular design; Allosteric enzyme; Scalability; Protein structure; Chemistry; Biology; Receptor; Biochemistry","score_opus":0.015342020891731258,"score_gpt":0.22283181615362244,"score_spread":0.20748979526189118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146099270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6896608,0.0001467861,0.30992183,0.00004854025,0.000059149723,0.00010069595,0.000010292589,0.0000067433707,0.000045152978],"genre_scores_gemma":[0.9372944,0.000008685366,0.062124666,0.00012082122,0.00012709957,0.000015848715,0.00028681604,0.000011499642,0.000010131965],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99932027,0.00003291051,0.00018513079,0.00025308016,0.000058522903,0.0001500905],"domain_scores_gemma":[0.99962246,0.000036309044,0.00007775501,0.00010007482,0.00010693314,0.00005643656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000996915,0.00010409996,0.00013780552,0.0000356911,0.000046273646,0.000008565582,0.0000932147,0.00019402374,0.00004447971],"category_scores_gemma":[0.000024929477,0.00009565461,0.00004305309,0.00004875821,0.000112350404,0.000001998627,0.000056343757,0.00010946041,0.0000014839012],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047543956,0.0000544947,0.0007404941,0.000012904684,0.000026700916,2.4888865e-7,0.000004659993,0.06973745,0.92813474,0.00086151896,0.000019452567,0.00035976956],"study_design_scores_gemma":[0.0003799519,0.00019438108,0.00008340012,0.000010329522,0.000010143344,0.0000054802094,0.0000033390074,0.52207315,0.47431833,0.002602353,0.00018793813,0.00013118456],"about_ca_topic_score_codex":0.0000066131884,"about_ca_topic_score_gemma":9.150272e-7,"teacher_disagreement_score":0.45381644,"about_ca_system_score_codex":0.0000024197616,"about_ca_system_score_gemma":0.000046784324,"threshold_uncertainty_score":0.39006814},"labels":[],"label_agreement":null},{"id":"W2146145035","doi":"10.1152/ajplung.00273.2010","title":"Paradoxical attenuation of β<sub>2</sub>-AR function in airway smooth muscle by G<sub>i</sub>-mediated counterregulation in transgenic mice overexpressing type 5 adenylyl cyclase","year":2010,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Immunovaccine (Canada)","funders":"National Heart, Lung, and Blood Institute","keywords":"Adenylyl cyclase; Transgene; Genetically modified mouse; Internal medicine; Endocrinology; Attenuation; Chemistry; Function (biology); Biology; Cell biology; Anatomy; Medicine; Biochemistry; Physics; Gene; Stimulation","score_opus":0.0031098349498221013,"score_gpt":0.20452184099627535,"score_spread":0.20141200604645326,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146145035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957484,0.0008473824,0.0028147337,0.000042688127,0.00034377375,0.00017756231,0.000014736886,0.0000056854874,0.000005015212],"genre_scores_gemma":[0.9987479,0.00047131954,0.00015228422,0.00017179853,0.00017318726,0.0000078122,0.00023583752,0.000038927104,9.4239505e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997932,0.0003837086,0.0006802695,0.0004595492,0.00017783814,0.0003666387],"domain_scores_gemma":[0.9988053,0.000059832633,0.00061079767,0.00024085678,0.00016406216,0.00011918679],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034889963,0.00028652762,0.0005910546,0.00017398775,0.000063409665,0.00001329833,0.00018360621,0.00029543354,0.000012844521],"category_scores_gemma":[0.00007239886,0.00027845678,0.00018288131,0.00027355136,0.00033385208,0.000029151523,0.000049243423,0.0004852743,0.0000015092946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007698549,0.00018713759,0.00011932456,0.00003334327,0.00007155635,0.0000039033494,0.00007738375,0.0008191013,0.994484,0.000015874391,0.00006383638,0.0033546505],"study_design_scores_gemma":[0.001240021,0.0012243139,0.010183505,0.000054306045,0.00005718082,0.000011007822,0.00012443513,0.0011692867,0.98532206,0.00019474492,0.00015581264,0.00026331315],"about_ca_topic_score_codex":0.000035734683,"about_ca_topic_score_gemma":0.0000298219,"teacher_disagreement_score":0.01006418,"about_ca_system_score_codex":0.000029448885,"about_ca_system_score_gemma":0.000105680745,"threshold_uncertainty_score":0.99996674},"labels":[],"label_agreement":null},{"id":"W2146517666","doi":"10.1016/j.tips.2007.10.001","title":"Neuronal Gq/11-coupled dopamine receptors: an uncharted role for dopamine","year":2007,"lang":"en","type":"review","venue":"Trends in Pharmacological Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse","keywords":"Dopamine; Neuroscience; Dopamine receptor; Dopamine receptor D3; Receptor; Dopaminergic; Schizophrenia (object-oriented programming); Signal transduction; Biology; Psychology; Cell biology; Psychiatry; Biochemistry","score_opus":0.10966889555518976,"score_gpt":0.4183224756795012,"score_spread":0.30865358012431143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146517666","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013144865,0.9830811,0.00046902258,0.000046447225,0.0014329418,0.000791621,0.00009189212,0.000059724058,0.00088240334],"genre_scores_gemma":[0.0038890513,0.98939,0.0024021498,0.00022212668,0.0016005285,0.00034005955,0.00097504404,0.000050002956,0.0011310007],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99658453,0.00025083084,0.0007564986,0.001224356,0.00036455184,0.0008192013],"domain_scores_gemma":[0.99901545,0.00014288345,0.00031857958,0.00020167153,0.00006461961,0.00025681613],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016708871,0.0005404851,0.0009708367,0.00034195813,0.00022956553,0.00008284909,0.0010019748,0.0005147242,0.0016347019],"category_scores_gemma":[0.000078532015,0.00037388044,0.00042637272,0.00091837056,0.00033050336,0.000015955133,0.0001905095,0.00029945976,0.000008575768],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052175816,0.00029602082,0.0000093685785,0.00016939678,0.000040514507,0.000008189675,0.00000874795,0.000045087036,0.023664504,0.000112185284,0.0004736139,0.9751202],"study_design_scores_gemma":[0.000622749,0.0016041842,0.0000057793045,0.00017252758,0.0001667786,0.000016890082,0.000029170516,0.0005730526,0.004742397,0.000058041063,0.99142873,0.0005796889],"about_ca_topic_score_codex":0.000017803715,"about_ca_topic_score_gemma":0.000046777655,"teacher_disagreement_score":0.9909551,"about_ca_system_score_codex":0.00005123761,"about_ca_system_score_gemma":0.00013168361,"threshold_uncertainty_score":0.9998713},"labels":[],"label_agreement":null},{"id":"W2147183145","doi":"10.1523/jneurosci.22-01-j0001.2002","title":"M5 Muscarinic Receptors Are Required for Prolonged Accumbal Dopamine Release after Electrical Stimulation of the Pons in Mice","year":2002,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Australian Research Council; Medical Research Council; Macquarie University","keywords":"Dopamine; Nucleus accumbens; Muscarinic acetylcholine receptor; Stimulation; Midbrain; Chemistry; Dopamine receptor; Neuroscience; Cholinergic neuron; Ventral tegmental area; Cholinergic; Endocrinology; Internal medicine; Receptor; Dopaminergic; Biology; Medicine; Central nervous system","score_opus":0.024548095533750404,"score_gpt":0.2614068444157958,"score_spread":0.23685874888204542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147183145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99809855,0.00019678134,0.0009544437,0.00019997929,0.0003837045,0.00015327783,0.0000030445842,0.0000011747029,0.000009059458],"genre_scores_gemma":[0.9991463,0.00006769604,0.00037945784,0.00016845521,0.00009976741,0.0000051999245,3.347565e-7,0.000007344393,0.00012545174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908894,0.00007608884,0.00032643208,0.00015736245,0.00019335547,0.00015779393],"domain_scores_gemma":[0.99935055,0.000027994864,0.00034028693,0.0001198348,0.000111826455,0.000049500264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028116824,0.00007604379,0.00012593696,0.00005866102,0.00004438562,0.000014784645,0.0002499909,0.00006341315,0.000008889388],"category_scores_gemma":[0.0007003705,0.000053572105,0.00011519686,0.00022973695,0.00005189484,0.000014074866,0.000040510786,0.00011420873,2.0389697e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016014233,0.000074944546,0.0034993794,0.0000054565658,0.0000016446234,0.000002901489,0.000027943575,0.00059679797,0.99471503,0.00000382115,0.00010720119,0.00080472446],"study_design_scores_gemma":[0.0013678737,0.0017262193,0.072737016,0.000074674244,0.00002692538,0.000095718395,0.000033987155,0.011177056,0.9101123,0.00007961789,0.0023929547,0.00017565534],"about_ca_topic_score_codex":0.0000011703132,"about_ca_topic_score_gemma":0.0000041093012,"teacher_disagreement_score":0.084602736,"about_ca_system_score_codex":0.00001579769,"about_ca_system_score_gemma":0.00003707727,"threshold_uncertainty_score":0.21846071},"labels":[],"label_agreement":null},{"id":"W2147198454","doi":"10.1124/mol.64.3.587","title":"Recruitment of RGS2 and RGS4 to the Plasma Membrane by G Proteins and Receptors Reflects Functional Interactions","year":2003,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"RGS2; Regulator of G protein signaling; G protein; Cell biology; GTPase-activating protein; G protein-coupled receptor; Gq alpha subunit; Biology; Vesicle-associated membrane protein 8; GTP-binding protein regulators; Receptor; Signal transduction; Membrane protein; Biochemistry; Membrane","score_opus":0.02367105375627194,"score_gpt":0.29412325326497174,"score_spread":0.2704521995086998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147198454","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882009,0.00092592,0.007987628,0.0009199746,0.00057126395,0.0007780014,0.000012451831,0.000007332863,0.0005965434],"genre_scores_gemma":[0.9962786,0.00020954851,0.0013823267,0.0010689865,0.00006321204,0.00026545188,0.000031361855,0.000020356205,0.00068015704],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990334,0.00020075738,0.00017605143,0.00030693563,0.000095930416,0.00018691283],"domain_scores_gemma":[0.99962646,0.000020445814,0.00006802849,0.00012286693,0.000060230923,0.00010198785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023087738,0.00013660965,0.00013338566,0.00004690975,0.000103602,0.000012405194,0.00007465979,0.00008135825,0.00027623336],"category_scores_gemma":[0.000047315196,0.000111627625,0.000042347892,0.00009273932,0.00006201837,0.0000036212143,0.000067368404,0.000108356944,0.000003697343],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001433829,0.00005131205,0.000016638169,0.0000108156155,0.00010454778,0.000001958851,0.000057863443,0.00010174914,0.9922907,0.00043819618,0.005410555,0.0013722765],"study_design_scores_gemma":[0.0005689912,0.00028010487,0.000005574183,0.0000042212328,0.000031689113,0.00003093187,0.00004559496,0.000031044343,0.7589292,0.00003454658,0.23994881,0.000089283116],"about_ca_topic_score_codex":0.000008250376,"about_ca_topic_score_gemma":0.000008050381,"teacher_disagreement_score":0.23453826,"about_ca_system_score_codex":0.000013196719,"about_ca_system_score_gemma":0.00003866106,"threshold_uncertainty_score":0.45520425},"labels":[],"label_agreement":null},{"id":"W2147350157","doi":"10.1074/jbc.m304082200","title":"Trafficking, Ubiquitination, and Down-regulation of the Human Platelet-activating Factor Receptor","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Ubiquitin; Cell biology; Receptor; Chemistry; Biology; Biochemistry; Gene","score_opus":0.019556335413583106,"score_gpt":0.24934964813294577,"score_spread":0.22979331271936265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147350157","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987955,0.0002874617,0.00040767886,0.000032823362,0.00006681118,0.00004395537,0.0000044616377,0.000002285386,0.00035903306],"genre_scores_gemma":[0.9990434,0.000048735725,0.000641624,0.000024729201,0.000148467,8.9815586e-7,0.000006218937,0.000006026592,0.00007987667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925226,0.00006000227,0.000343432,0.00012105175,0.00011699898,0.00010624165],"domain_scores_gemma":[0.9992534,0.000022861175,0.00044624807,0.000091863614,0.00013778835,0.00004782769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026504367,0.00009848529,0.0001538037,0.0000098816845,0.000083560975,0.000013180001,0.000120938195,0.00018527001,0.00024883504],"category_scores_gemma":[0.0003338411,0.000060105584,0.00010692239,0.00004969002,0.00007357754,0.000004681124,0.00002983599,0.00013438199,1.4077524e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014396675,0.000028252947,0.0010710825,0.00001446422,0.000020733754,2.2391046e-7,0.000028573035,0.000023414957,0.9974379,0.000071964794,0.000054519624,0.0012344532],"study_design_scores_gemma":[0.00028558343,0.00011390159,0.002499753,0.000029744398,0.0000025206652,0.000033185508,0.00010688026,0.000003748822,0.99166775,0.00016833463,0.005011412,0.000077196666],"about_ca_topic_score_codex":4.756347e-7,"about_ca_topic_score_gemma":1.00598925e-7,"teacher_disagreement_score":0.0057701813,"about_ca_system_score_codex":0.0000123664395,"about_ca_system_score_gemma":0.000030488807,"threshold_uncertainty_score":0.27245694},"labels":[],"label_agreement":null},{"id":"W2147525051","doi":"10.1093/protein/gzq099","title":"Dissecting the molecular determinants of ligand-binding-induced macromolecular switching using thermodynamic cycles","year":2010,"lang":"en","type":"article","venue":"Protein Engineering Design and Selection","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chemistry; Ligand (biochemistry); Macromolecule; Biophysics; Biology; Biochemistry; Receptor","score_opus":0.00850766139695489,"score_gpt":0.2287279364206217,"score_spread":0.2202202750236668,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147525051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.689567,0.00007735478,0.31000054,0.0000030442338,0.00008877103,0.00024550204,3.1260544e-7,0.000014849708,0.0000025617276],"genre_scores_gemma":[0.9895704,0.000005743115,0.010262096,0.0000042961456,0.00008682066,0.00002484035,0.0000015252673,0.000036757043,0.0000075158555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992441,0.000037729533,0.00018132389,0.00022971212,0.00010314761,0.00020397734],"domain_scores_gemma":[0.9996804,0.000012953646,0.00009062172,0.000114600705,0.000059403497,0.00004201489],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004143118,0.00015643994,0.0001280506,0.00005737437,0.00013857214,0.00004146834,0.000102347345,0.00013588763,0.000002505134],"category_scores_gemma":[0.000102233025,0.00012947676,0.000058123984,0.00010910749,0.000012235383,0.000007924664,0.00003604686,0.0001954828,2.3484407e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001807656,0.000010384858,0.00011523884,0.000026744541,0.000024775254,0.0000015247142,0.000057377354,0.0033400566,0.994942,0.00013299247,7.57347e-8,0.001330757],"study_design_scores_gemma":[0.00011802798,0.00009979521,0.00008445814,0.0000359744,0.000014451901,0.00003925981,0.000016562231,0.19106622,0.80830693,0.00008558406,0.0000042641095,0.00012845529],"about_ca_topic_score_codex":0.00002939183,"about_ca_topic_score_gemma":0.000004989002,"teacher_disagreement_score":0.30000335,"about_ca_system_score_codex":0.000007921174,"about_ca_system_score_gemma":0.000022990005,"threshold_uncertainty_score":0.5279909},"labels":[],"label_agreement":null},{"id":"W2147992661","doi":"10.1016/j.bpj.2008.12.782","title":"Oligomeric Size of the M2 Muscarinic Receptor in Live Cells as Determined from FRET Efficiencies at the Level of Single Pixels","year":2009,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Förster resonance energy transfer; Tetramer; Fluorescence; Oligomer; Physics; Chemistry; Crystallography; Optics; Nuclear magnetic resonance","score_opus":0.02204905828791866,"score_gpt":0.2414117272651967,"score_spread":0.21936266897727802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147992661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99910223,0.0001299981,0.00016001235,0.00012761248,0.00025257687,0.00009175619,0.000032511223,0.0000016099841,0.00010170691],"genre_scores_gemma":[0.998896,0.00006329576,0.00036782786,0.00015108591,0.00027289244,0.0000012804891,0.000002919139,0.00000873643,0.00023598826],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989728,0.00011541002,0.00032053262,0.00016894692,0.0002307449,0.0001915743],"domain_scores_gemma":[0.9992919,0.00008097587,0.00026027134,0.00024107682,0.000072088995,0.00005369674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015212099,0.00012906986,0.00021006608,0.000017135682,0.00008418717,0.000017722032,0.00037727522,0.000093933064,0.00014482012],"category_scores_gemma":[0.00008413791,0.000073719624,0.00023196016,0.00012538244,0.00013246492,0.000004331403,0.00010476798,0.00014293204,0.0000074792047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007869718,0.00014128214,0.000058517217,0.0000022279335,0.000017939094,9.83921e-7,0.00022669506,0.00008739538,0.9975993,0.000012395275,0.00011935059,0.0016552396],"study_design_scores_gemma":[0.00034164175,0.00055321335,0.0034989084,0.00003688695,0.00001645073,0.00000644178,0.00017511043,0.000043912245,0.99476427,0.00017895525,0.0002907466,0.00009344071],"about_ca_topic_score_codex":0.00005076723,"about_ca_topic_score_gemma":0.000011173689,"teacher_disagreement_score":0.0034403913,"about_ca_system_score_codex":0.000024879997,"about_ca_system_score_gemma":0.00006108504,"threshold_uncertainty_score":0.3006199},"labels":[],"label_agreement":null},{"id":"W2149115445","doi":"10.1152/ajplung.00046.2008","title":"Effect of β<sub>2</sub>-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A","year":2008,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Protein kinase A; Kinase; β2 adrenergic receptor; Gene; Gene expression; Cell biology; Adrenergic receptor; Pharmacology; Agonist; Biology; Receptor; Chemistry; Biochemistry","score_opus":0.0041835517754624995,"score_gpt":0.224982183760409,"score_spread":0.22079863198494648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149115445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979907,0.0008102561,0.00064906763,0.0000063866537,0.00006999661,0.0004499233,0.000012363386,0.000004772165,0.0000064952933],"genre_scores_gemma":[0.9986598,0.00010453683,0.000832705,0.00011479716,0.00015921485,0.00004604319,0.00002808136,0.0000505331,0.000004303192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980518,0.0004665909,0.00052920013,0.00045632737,0.00013369092,0.00036238442],"domain_scores_gemma":[0.99879676,0.00004700954,0.00067959377,0.0002501497,0.000096627264,0.00012985166],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038530288,0.00032255714,0.00070601923,0.0001507384,0.00012750838,0.0000065192808,0.00018782567,0.00017527261,0.0000070608676],"category_scores_gemma":[0.000051057206,0.00027269838,0.00021980109,0.000089776004,0.0003933094,0.000009385375,0.00010458756,0.00020804854,3.8353687e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011531344,0.00010054643,0.00011704532,0.000121400924,0.00010924392,0.000014270309,0.00020182571,0.00028416983,0.9970005,0.000016121454,0.000024019422,0.0008576836],"study_design_scores_gemma":[0.001722167,0.0062818765,0.00040788794,0.00012001634,0.000036973313,0.000024613215,0.0000780474,0.00011674185,0.99075013,0.00010411129,0.00010846886,0.00024899034],"about_ca_topic_score_codex":0.000012367297,"about_ca_topic_score_gemma":9.751709e-7,"teacher_disagreement_score":0.0062504327,"about_ca_system_score_codex":0.000019731511,"about_ca_system_score_gemma":0.000059483013,"threshold_uncertainty_score":0.9999725},"labels":[],"label_agreement":null},{"id":"W2149590941","doi":"10.1016/j.bmcl.2006.02.062","title":"Identification of an indole series of prostaglandin D2 receptor antagonists","year":2006,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada); TransCanada (Canada)","funders":"","keywords":"Chemistry; Indole test; Receptor; Prostaglandin D2; Stereochemistry; IC50; Pharmacology; Biochemistry; In vitro; Biology","score_opus":0.005159303729391729,"score_gpt":0.21312547333021764,"score_spread":0.20796616960082592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149590941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982436,0.00024107771,0.00083140854,0.00031268067,0.00013186592,0.0001151794,0.000049405007,0.000012178637,0.00006262793],"genre_scores_gemma":[0.9983272,0.000029557097,0.0004272648,0.000059460825,0.0004770966,0.0000075618104,0.00045974235,0.000023358061,0.00018876875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987617,0.000030133584,0.00046814588,0.0003063395,0.00024656986,0.00018712255],"domain_scores_gemma":[0.9992208,0.0000056816734,0.00031862393,0.00030344594,0.00008925351,0.00006219152],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025755004,0.00015952716,0.00020913398,0.000024515764,0.00004594888,0.0000109717,0.00021909465,0.00014141577,0.00016833599],"category_scores_gemma":[0.00004247289,0.00015142112,0.00006794565,0.00011078555,0.00016460556,0.000009597218,0.00003893677,0.00007760971,0.0000020167838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011074698,0.00006966795,0.000614305,0.0001346543,0.000023290999,0.0000019780632,0.000057946698,0.0000054326715,0.99796337,0.0000131175475,0.0008370166,0.0001684472],"study_design_scores_gemma":[0.00045280077,0.000097301294,0.00045923554,0.000035991237,0.000023424062,0.000024878182,0.0002379654,0.0000075822654,0.9974902,0.000022976297,0.0009982605,0.00014937208],"about_ca_topic_score_codex":0.000044790646,"about_ca_topic_score_gemma":0.0000031399545,"teacher_disagreement_score":0.00047318358,"about_ca_system_score_codex":0.000020340918,"about_ca_system_score_gemma":0.00006227393,"threshold_uncertainty_score":0.6174774},"labels":[],"label_agreement":null},{"id":"W2149644918","doi":"10.1152/jn.00190.2003","title":"A Minimal Model for G Protein–Mediated Synaptic Facilitation and Depression","year":2003,"lang":"en","type":"article","venue":"Journal of Neurophysiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Biophysics; Neuroscience; Protein subunit; Facilitation; G protein; Receptor; Neurotransmission; Chemistry; Biology; Biochemistry","score_opus":0.015601957927998119,"score_gpt":0.24417836061393478,"score_spread":0.22857640268593665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149644918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96773165,0.0001471264,0.03185801,0.000019551122,0.0001017646,0.00012247032,0.0000047063368,0.0000016421075,0.000013051671],"genre_scores_gemma":[0.99371594,0.000051939754,0.005983462,0.000093416376,0.00007496094,0.000007826715,0.0000049935215,0.000010508237,0.000056945533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99942136,0.00007205949,0.00020741238,0.00013185522,0.00005210418,0.00011522568],"domain_scores_gemma":[0.9995722,0.00002130907,0.0001482895,0.00006784769,0.00013725647,0.000053074167],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006598587,0.00007920397,0.00013714826,0.000035910474,0.00004131081,0.0000063475077,0.000055853543,0.000084478306,0.0000049230066],"category_scores_gemma":[0.00043505622,0.00006280005,0.00006592025,0.00002223714,0.000027633296,0.000004575195,0.000014446835,0.000066846456,4.6412362e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023688865,0.000024324094,0.000007253075,0.000014581886,0.000020756303,0.0000021886253,0.000029263492,0.001929238,0.99727255,0.00007579889,0.000029438606,0.0003577121],"study_design_scores_gemma":[0.0024946053,0.0047117667,0.00045301535,0.000039001272,0.000053507418,0.00017542916,0.00012728195,0.054813802,0.9307202,0.0036144897,0.0025134569,0.00028345583],"about_ca_topic_score_codex":2.2114591e-7,"about_ca_topic_score_gemma":1.17037345e-7,"teacher_disagreement_score":0.06655236,"about_ca_system_score_codex":0.0000032154685,"about_ca_system_score_gemma":0.00004328389,"threshold_uncertainty_score":0.25609118},"labels":[],"label_agreement":null},{"id":"W2149690772","doi":"10.4049/jimmunol.174.12.7479","title":"Agonist Activity of the Small Molecule C3aR Ligand SB 290157","year":2005,"lang":"en","type":"letter","venue":"The Journal of Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Agonist; Ligand (biochemistry); Chemistry; Molecule; Receptor; Stereochemistry; Biochemistry; Organic chemistry","score_opus":0.011147667690297633,"score_gpt":0.2181055071464483,"score_spread":0.20695783945615068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149690772","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.888521,0.008515876,0.00077259867,0.09997057,0.0014382425,0.00020017405,0.000023770986,0.0000034777527,0.0005542903],"genre_scores_gemma":[0.9074215,0.004995636,0.00037591805,0.07687045,0.006107141,0.0000054966376,0.00002793913,0.0001189181,0.0040769805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99837947,0.00048040805,0.00047800838,0.00015573447,0.00020188301,0.0003044908],"domain_scores_gemma":[0.997943,0.00006215306,0.0011337547,0.00061662367,0.00022262326,0.000021890844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005751007,0.00025688147,0.00044554385,0.000058124282,0.00013097141,0.000016936932,0.0011338032,0.0007590779,0.000063177285],"category_scores_gemma":[0.00009202389,0.00014327835,0.00041618818,0.00007223712,0.00027679387,0.0000033999838,0.00026860024,0.0014704675,0.0000040857417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016488812,0.000030480907,0.000004456758,0.000016332588,0.00041270873,0.000010640916,0.000060800576,0.00003074676,0.9451184,0.00000625634,0.053168908,0.00097532716],"study_design_scores_gemma":[0.00032899002,0.00041814143,0.0000463598,0.000050323255,0.00013522379,0.00040769068,0.000028819863,0.0000025314866,0.77140266,0.00005494293,0.2269972,0.00012711475],"about_ca_topic_score_codex":0.000033545395,"about_ca_topic_score_gemma":0.000012512599,"teacher_disagreement_score":0.1738283,"about_ca_system_score_codex":0.00003119398,"about_ca_system_score_gemma":0.00023619785,"threshold_uncertainty_score":0.63885313},"labels":[],"label_agreement":null},{"id":"W2149757555","doi":"10.1091/mbc.e06-03-0218","title":"Opposite Effects of PSD-95 and MPP3 PDZ Proteins on Serotonin 5-Hydroxytryptamine<sub>2C</sub>Receptor Desensitization and Membrane Stability","year":2006,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Centre National de la Recherche Scientifique","keywords":"Biology; PDZ domain; Desensitization (medicine); Receptor; Serotonin; Cell biology; 5-HT receptor; Membrane protein; Biophysics; Membrane; Biochemistry","score_opus":0.002648029146960051,"score_gpt":0.18323627090484543,"score_spread":0.18058824175788538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2149757555","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99344635,0.0013023205,0.0042816927,0.000078383586,0.00009898027,0.0006905992,0.000021605545,0.0000071468758,0.00007290323],"genre_scores_gemma":[0.99858904,0.00016282334,0.000993922,0.00008377451,0.00003649996,0.000022464665,0.00006828844,0.00002194596,0.000021256592],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880946,0.00026697884,0.00025212034,0.000379722,0.00009322014,0.00019848178],"domain_scores_gemma":[0.9993184,0.0000326982,0.00018647862,0.00033806727,0.00007673078,0.00004760702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021143912,0.00019728212,0.0002550819,0.00003361611,0.000068233196,0.000007666723,0.00013180469,0.00026100877,0.00000467795],"category_scores_gemma":[0.000060453363,0.0001534525,0.00009630295,0.000079621714,0.00023196649,0.0000028927018,0.0001379577,0.00009579592,7.791427e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007372229,0.00009305109,0.0009054663,0.0001808119,0.00002990596,0.0000010314674,0.000020261397,0.000080535145,0.9979869,0.00020660473,0.000017390616,0.00040430386],"study_design_scores_gemma":[0.00061954686,0.00057544047,0.0005218929,0.000043209755,0.000033761673,0.0000043618297,0.000008670121,0.00019710649,0.9973956,0.00034942167,0.000098603836,0.00015240126],"about_ca_topic_score_codex":0.000047938982,"about_ca_topic_score_gemma":0.000008675984,"teacher_disagreement_score":0.005142656,"about_ca_system_score_codex":0.0000088276565,"about_ca_system_score_gemma":0.000026687216,"threshold_uncertainty_score":0.62576115},"labels":[],"label_agreement":null},{"id":"W2150373538","doi":"10.1039/c5md00400d","title":"Discovery of trace amine-associated receptor 1 ligands by molecular docking screening against a homology model","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; Toronto Public Health; University of New Brunswick","funders":"National Supercomputer Centre, Linköpings Universitet; Vetenskapsrådet; Stiftelsen för Strategisk Forskning; Canadian Institutes of Health Research; Sven och Lilly Lawskis Fond för Naturvetenskaplig Forskning","keywords":"Docking (animal); Homology modeling; Computational biology; Amine gas treating; Chemistry; Homology (biology); Stereochemistry; Receptor; TRACE (psycholinguistics); Combinatorial chemistry; Biology; Biochemistry; Medicine; Amino acid; Organic chemistry; Philosophy; Enzyme","score_opus":0.017648548986714595,"score_gpt":0.2446794523600405,"score_spread":0.2270309033733259,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150373538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92416626,0.0015607703,0.0731774,0.00012431525,0.00012119822,0.0001239876,0.000056680437,0.000021683642,0.0006477305],"genre_scores_gemma":[0.9951845,0.000084405394,0.003249903,0.00024462663,0.00006543805,0.000020166932,0.00042829165,0.00004895599,0.00067372574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99857783,0.00007395378,0.00035901024,0.0003782354,0.0002523907,0.00035857278],"domain_scores_gemma":[0.9991459,0.000017834735,0.00021027483,0.00034478653,0.00014958203,0.0001316093],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004798176,0.00023199587,0.00033295763,0.000052143198,0.00005600864,0.000030499,0.00030727652,0.0002877906,0.000007327753],"category_scores_gemma":[0.00023472263,0.00022966541,0.0001581748,0.000134736,0.00007106199,0.000013272677,0.00015948674,0.00016092225,0.000002352094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067027744,0.00010040998,0.00026859617,0.000010189315,0.00009177152,0.0000032536464,0.000153403,0.004033146,0.99060524,0.000055377273,0.0034308487,0.0011807241],"study_design_scores_gemma":[0.00092335127,0.00021988119,0.0000053095064,0.000038900933,0.000025040463,0.000003387134,0.00021600825,0.0086975545,0.9877886,0.00012889392,0.0016852653,0.00026777986],"about_ca_topic_score_codex":0.000028080482,"about_ca_topic_score_gemma":0.000006909204,"teacher_disagreement_score":0.071018256,"about_ca_system_score_codex":0.000030115167,"about_ca_system_score_gemma":0.00008900295,"threshold_uncertainty_score":0.93654835},"labels":[],"label_agreement":null},{"id":"W2150448038","doi":"10.1016/s0006-3495(04)74256-3","title":"First Principles Predictions of the Structure and Function of G-Protein-Coupled Receptors: Validation for Bovine Rhodopsin","year":2004,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Army Research Office; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Office of Naval Research; Beckman Institute for Advanced Science and Technology, University of Illinois, Urbana-Champaign; General Motors of Canada; U.S. Department of Energy; National Science Foundation; National Institutes of Health; National Institute of Allergy and Infectious Diseases; International Business Machines Corporation","keywords":"Rhodopsin; G protein-coupled receptor; Transmembrane domain; Chemistry; Ligand (biochemistry); Protein structure; Helix (gastropod); Crystallography; Receptor; Biology; Biochemistry","score_opus":0.011741634593468943,"score_gpt":0.22427716965728378,"score_spread":0.21253553506381484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2150448038","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.952144,0.00004730034,0.04725936,0.00013092821,0.00022500414,0.00016252359,0.00002461963,0.0000021558428,0.000004109763],"genre_scores_gemma":[0.9971532,0.000025581314,0.00234423,0.000008718159,0.00041026645,0.0000033854317,0.000014509308,0.0000086026,0.00003145869],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949056,0.000019300142,0.00019427887,0.000105028106,0.000108175554,0.00008267619],"domain_scores_gemma":[0.99954647,0.000006936665,0.00018888123,0.00009870587,0.00012244281,0.0000365931],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008706941,0.00007333769,0.0000994755,0.00001812341,0.00012220205,0.000012840904,0.00007696666,0.00007752026,0.00001654677],"category_scores_gemma":[0.00006143114,0.000049277794,0.00009908773,0.00005620321,0.00005300071,0.0000061078763,0.000031280895,0.00006927601,9.104143e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012779051,0.00003657555,0.000060470196,0.000022665103,0.000036187164,3.4304176e-8,0.000023198472,0.0019199665,0.9966166,0.00092989556,0.000012503985,0.0002140923],"study_design_scores_gemma":[0.00056329963,0.0006075777,0.00091251923,0.000048956746,0.00003365114,0.0000068364625,0.00002974454,0.00031259796,0.99556893,0.0011788332,0.00068335864,0.00005366514],"about_ca_topic_score_codex":0.0000056286444,"about_ca_topic_score_gemma":0.0000032470418,"teacher_disagreement_score":0.045009248,"about_ca_system_score_codex":0.000011174976,"about_ca_system_score_gemma":0.00004673529,"threshold_uncertainty_score":0.20094903},"labels":[],"label_agreement":null},{"id":"W2151526347","doi":"10.1074/jbc.m910348199","title":"Differential Affinities of Visual Arrestin, βArrestin1, and βArrestin2 for G Protein-coupled Receptors Delineate Two Major Classes of Receptors","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":882,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Heart and Stroke Foundation of Canada; National Heart, Lung, and Blood Institute; National Institutes of Health; Bristol-Myers Squibb; Howard Hughes Medical Institute","keywords":"Arrestin; G protein-coupled receptor; Receptor; Rhodopsin-like receptors; Enzyme-linked receptor; Cell biology; Class C GPCR; Biology; 5-HT5A receptor; Agonist; 5-HT1 receptor; Chemistry; Metabotropic receptor; Biochemistry","score_opus":0.017635646457818087,"score_gpt":0.2670462834610481,"score_spread":0.24941063700323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151526347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975812,0.0007170505,0.0011643072,0.000040477826,0.00017799642,0.00019626429,0.000027275239,0.0000075850116,0.000087866014],"genre_scores_gemma":[0.9935808,0.00033886565,0.00507267,0.000017359785,0.0006598058,0.000014175029,0.000052418014,0.000020988817,0.00024290533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99829495,0.00006443565,0.00089086103,0.0002794599,0.00019707308,0.00027319894],"domain_scores_gemma":[0.9986081,0.00009055354,0.0006657114,0.00014172953,0.00034536494,0.00014854236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033229843,0.00025902418,0.00054524356,0.00003450694,0.00006631287,0.000018611145,0.0002567077,0.00031489012,0.00084330887],"category_scores_gemma":[0.0005818557,0.0001894998,0.0002710255,0.000080712896,0.00026235654,0.000008276164,0.00006482846,0.00019531998,4.4189272e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012006916,0.00016293894,0.0009296225,0.00012730599,0.0000970842,0.0000023893645,0.000018049112,0.00005933921,0.9925818,0.000006928325,0.00012526965,0.0046885805],"study_design_scores_gemma":[0.0014391317,0.0012453839,0.00012658178,0.00016309333,0.00005202834,0.000040563835,0.00014635747,0.00018038614,0.9944932,0.00018493384,0.0017105351,0.00021781662],"about_ca_topic_score_codex":0.0000070310884,"about_ca_topic_score_gemma":9.965189e-7,"teacher_disagreement_score":0.004470764,"about_ca_system_score_codex":0.000011593271,"about_ca_system_score_gemma":0.00009366569,"threshold_uncertainty_score":0.92336404},"labels":[],"label_agreement":null},{"id":"W2152482698","doi":"10.1529/biophysj.107.115188","title":"Inferring the Lifetime of Endosomal Protein Complexes by Fluorescence Recovery after Photobleaching","year":2007,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Photobleaching; G protein-coupled receptor; Receptor; Fluorescence recovery after photobleaching; Endosome; Vesicle; Biophysics; Compartmentalization (fire protection); Chemistry; Signal transduction; Cytosol; Fluorescence; Biology; Biochemistry; Membrane; Physics; Enzyme","score_opus":0.0060483360079749745,"score_gpt":0.2261544736643787,"score_spread":0.22010613765640374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152482698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98719865,0.00016518497,0.012233488,0.00005144354,0.00010989752,0.00010687947,0.000008469938,0.000004362865,0.0001215984],"genre_scores_gemma":[0.9975582,0.00002573573,0.0016450945,0.000080422105,0.0005937254,0.0000044588514,0.00000546779,0.000015176861,0.00007175069],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999044,0.00006161815,0.00027334818,0.00015374723,0.00021039083,0.00025687317],"domain_scores_gemma":[0.99953645,0.000020917405,0.00014339665,0.00014726458,0.00005857966,0.000093396186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038492781,0.0001236164,0.00013465332,0.000023592396,0.00012494487,0.000045586814,0.00022065233,0.00007570067,0.000058410533],"category_scores_gemma":[0.00004599473,0.000083900995,0.0001548311,0.000057180412,0.0000762921,0.000008317529,0.00008187496,0.00023426733,0.000004481331],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023529408,0.000055571167,0.00011321932,0.0000068007107,0.000031705044,0.0000055339815,0.000031561358,0.000009429208,0.99637413,0.00005869048,0.00013504925,0.0029430236],"study_design_scores_gemma":[0.00021313048,0.0003224353,0.00044879655,0.000046435405,0.000009049943,0.000025441104,0.000045816876,0.000044363584,0.9970065,0.00009785294,0.0016291757,0.00011103228],"about_ca_topic_score_codex":0.0000148895115,"about_ca_topic_score_gemma":0.0000015282757,"teacher_disagreement_score":0.0105883945,"about_ca_system_score_codex":0.000011651957,"about_ca_system_score_gemma":0.00003013467,"threshold_uncertainty_score":0.34213832},"labels":[],"label_agreement":null},{"id":"W2152553804","doi":"10.1124/mol.113.089003","title":"Endocytic Profiles of δ-Opioid Receptor Ligands Determine the Duration of Rapid but Not Sustained cAMP Responses","year":2013,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health; Québec Consortium for Drug Discovery","keywords":"Internalization; Chemistry; Enkephalin; Opioid receptor; Ligand (biochemistry); Receptor; Opioid; Biophysics; Stereochemistry; Biochemistry; Biology","score_opus":0.009705185968700214,"score_gpt":0.2565868865312578,"score_spread":0.24688170056255757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152553804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961004,0.0006575144,0.0018140048,0.00037425113,0.00029121427,0.0006485026,0.000024396075,0.00000987737,0.000079817066],"genre_scores_gemma":[0.99776894,0.00019384356,0.0007549921,0.00047557635,0.00014260704,0.0001559679,0.00005745049,0.000027166512,0.00042346484],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860877,0.0002363205,0.0004475045,0.00027782688,0.00015766539,0.00027190553],"domain_scores_gemma":[0.99903995,0.000065847205,0.00027403623,0.00026838013,0.00028829311,0.00006348308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030946088,0.00017968159,0.00024973167,0.000075998105,0.00006661903,0.00001161276,0.00027812013,0.00015024884,0.0009047042],"category_scores_gemma":[0.00014994283,0.00013757273,0.00014305681,0.000109798,0.00016081189,0.000006832331,0.00011663223,0.000103691,0.000010707631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003590524,0.00005794354,0.000042546166,0.000051557894,0.000109702996,0.000004764681,0.00009545427,0.00003390218,0.99694514,0.00008622979,0.0009560135,0.0012577187],"study_design_scores_gemma":[0.0008499618,0.00068354607,0.000082571416,0.000008753121,0.00005816198,0.000014071592,0.00019509428,0.00027265263,0.99579364,0.000061052546,0.001840139,0.00014033321],"about_ca_topic_score_codex":0.00003141103,"about_ca_topic_score_gemma":0.000001048426,"teacher_disagreement_score":0.001668509,"about_ca_system_score_codex":0.000015796473,"about_ca_system_score_gemma":0.00015225695,"threshold_uncertainty_score":0.99058765},"labels":[],"label_agreement":null},{"id":"W2152568000","doi":"10.1073/pnas.97.3.1119","title":"Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity","year":2000,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":183,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; Medical Research Council; National Institutes of Health; Medical Research Council Canada","keywords":"Internalization; Endocytic cycle; Biology; G protein-coupled receptor kinase; G protein-coupled receptor; Cell biology; Receptor; GTPase-activating protein; Signal transducing adaptor protein; Clathrin; G protein; Arrestin; Signal transduction; Endocytosis; Biochemistry","score_opus":0.02128126993717284,"score_gpt":0.2506328744260926,"score_spread":0.22935160448891978,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152568000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99887425,0.00014994448,0.000012329282,0.00014772905,0.000010675889,0.00021471706,0.000028878609,0.0000042684865,0.00055718044],"genre_scores_gemma":[0.9983518,0.000039559014,0.0012594649,0.00006422422,0.00004872188,0.0000075812945,0.0000016578534,0.0000048655857,0.0002221197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880445,0.0000112139705,0.00029293547,0.00022634474,0.0005317746,0.00013329335],"domain_scores_gemma":[0.9994038,0.000026280995,0.00027100742,0.000010257721,0.00025853468,0.000030173947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00090470753,0.00009218745,0.00014066698,0.000041966436,0.00009861788,0.000008674329,0.00029390608,0.00010303539,0.000060887684],"category_scores_gemma":[0.00036658606,0.000065273605,0.00008642651,0.0002684481,0.00032473158,0.00001782638,0.00005699237,0.00007667841,6.962462e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003208563,0.00003693327,0.0003659772,0.00002238273,0.000012665344,2.5299645e-9,0.000030980395,0.00017953897,0.9979619,0.00035482214,0.00017846408,0.0008242484],"study_design_scores_gemma":[0.00021399737,0.000092785,0.00029159486,0.000042271196,0.0000054884104,0.0000025770325,0.000062394545,0.0046807304,0.99335164,0.0007622324,0.00042100358,0.000073293515],"about_ca_topic_score_codex":0.000012468054,"about_ca_topic_score_gemma":1.2535551e-7,"teacher_disagreement_score":0.0046102675,"about_ca_system_score_codex":0.000010024417,"about_ca_system_score_gemma":0.0000426301,"threshold_uncertainty_score":0.26617804},"labels":[],"label_agreement":null},{"id":"W2153090506","doi":"10.1371/journal.pone.0027538","title":"M5 Muscarinic Receptors Mediate Striatal Dopamine Activation by Ventral Tegmental Morphine and Pedunculopontine Stimulation in Mice","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Nipissing University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Ventral tegmental area; Nucleus accumbens; Dopamine; Pedunculopontine Tegmental Nucleus; Chemistry; Endocrinology; Pedunculopontine nucleus; Internal medicine; Muscarinic acetylcholine receptor; Muscarinic acetylcholine receptor M4; Dopamine receptor; Mesolimbic pathway; Neuroscience; Pharmacology; Dopaminergic; Biology; Cholinergic; Receptor; Medicine; Deep brain stimulation; Parkinson's disease","score_opus":0.027075084792151573,"score_gpt":0.21040296694219213,"score_spread":0.18332788215004056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153090506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991048,0.00019708766,0.00027803666,0.00003532863,0.00006064405,0.00021099021,0.000017031967,0.000010809601,0.000085244996],"genre_scores_gemma":[0.9969859,0.00020397955,0.0018437293,0.00003344647,0.00014036606,0.000016959024,0.00059389253,0.000018709638,0.00016301867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991792,0.000036096942,0.00020530462,0.00026239254,0.00014106232,0.00017595683],"domain_scores_gemma":[0.9996982,0.000008994526,0.000086370535,0.00009824386,0.00003224255,0.000075916934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014578982,0.0001248399,0.0001399053,0.000044352022,0.000035261455,0.000011846583,0.00006860303,0.00010761387,0.00023726834],"category_scores_gemma":[0.00006971852,0.00012659568,0.000025973404,0.000068071975,0.000022933677,0.00001393821,0.00005192477,0.00008430004,0.000003352069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014924195,0.00040847587,0.0056263567,0.000017205837,0.000050538492,5.760498e-7,0.00010921762,0.0000046159867,0.9927535,0.0000075309017,0.000049305545,0.0008234575],"study_design_scores_gemma":[0.0010026462,0.0003287784,0.0038094285,0.000039409184,0.000029294211,6.3961585e-7,0.0000719038,0.0003201209,0.99415904,0.00003436573,0.000053003874,0.00015139437],"about_ca_topic_score_codex":0.000090813526,"about_ca_topic_score_gemma":0.00002319417,"teacher_disagreement_score":0.0021189274,"about_ca_system_score_codex":0.000019689447,"about_ca_system_score_gemma":0.000017627022,"threshold_uncertainty_score":0.5162422},"labels":[],"label_agreement":null},{"id":"W2153137205","doi":"10.1186/2051-5960-1-66","title":"G-protein coupled receptor expression patterns delineate medulloblastoma subgroups","year":2013,"lang":"en","type":"article","venue":"Acta Neuropathologica Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Eye Institute; National Cancer Institute; National Institutes of Health; Children's Health Foundation; Deutsche Krebshilfe; Alex's Lemonade Stand Foundation for Childhood Cancer","keywords":"Medulloblastoma; Wnt signaling pathway; G protein-coupled receptor; Druggability; Biology; Cancer research; Bioinformatics; Sonic hedgehog; Computational biology; Medicine; Signal transduction; Genetics; Gene","score_opus":0.019440245314776762,"score_gpt":0.24437130356707676,"score_spread":0.2249310582523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153137205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930735,0.0002530006,0.004392082,0.0011324191,0.00010124619,0.00049819436,0.00002726345,0.000078677724,0.0004436004],"genre_scores_gemma":[0.9865599,0.0007510591,0.010812293,0.0005562486,0.00009466112,0.00034949675,0.00042302214,0.000040848827,0.00041243472],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99836516,0.0004221153,0.00034944343,0.00041108986,0.00014574127,0.0003064423],"domain_scores_gemma":[0.9975335,0.0000442191,0.00017100379,0.001921865,0.00019974214,0.00012967201],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023349519,0.00022429242,0.00018183344,0.000047282683,0.0003778664,0.000080036116,0.0011855464,0.00017417969,0.0007635567],"category_scores_gemma":[0.00021474095,0.00018932264,0.00010284171,0.00010398997,0.00010605622,0.000016155962,0.0008443434,0.0002529318,0.0001825738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015570435,0.00010309785,0.00036005376,0.0000042758957,0.0000063893567,0.0000013820829,0.000030133962,0.000006555135,0.9976737,0.00008290858,0.0008096768,0.00090628135],"study_design_scores_gemma":[0.0005228455,0.000671813,0.0032079646,0.00005390373,0.00001725572,0.000039221264,0.00024863507,0.0016256927,0.9597969,0.0001870164,0.033107683,0.000521087],"about_ca_topic_score_codex":0.00003421229,"about_ca_topic_score_gemma":0.00000957436,"teacher_disagreement_score":0.037876796,"about_ca_system_score_codex":0.000010663849,"about_ca_system_score_gemma":0.000024111043,"threshold_uncertainty_score":0.83604103},"labels":[],"label_agreement":null},{"id":"W2153415726","doi":"10.1093/cvr/cvp392","title":"Desensitization of vascular endothelin receptors by G protein-coupled receptor kinase 2","year":2009,"lang":"en","type":"letter","venue":"Cardiovascular Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Desensitization (medicine); Receptor; Endothelin receptor; Homologous desensitization; Internal medicine; Medicine; Endocrinology; Pharmacology; Biology","score_opus":0.02367327023235508,"score_gpt":0.27231196459048096,"score_spread":0.24863869435812588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2153415726","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3494507,0.37769425,0.13416839,0.09241407,0.0060185,0.030423937,0.0019629046,0.00061342336,0.007253851],"genre_scores_gemma":[0.26417035,0.10383425,0.049453013,0.17425977,0.1206051,0.006979175,0.13147974,0.007145741,0.14207286],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99263084,0.0018213693,0.00067670917,0.001390012,0.0024040807,0.001076975],"domain_scores_gemma":[0.9961199,0.000051324212,0.00019117379,0.002083629,0.0013760135,0.00017791781],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.004078035,0.0005741906,0.0010497988,0.00038534068,0.00024211411,0.00010140612,0.0008325695,0.0019176563,0.00033330443],"category_scores_gemma":[0.0006751674,0.0005711369,0.0019366352,0.00053260796,0.00027690578,0.000010052549,0.00025969849,0.0018287876,0.000089199886],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039776973,0.000037594855,0.0000018225813,0.0002096934,0.0011264723,0.00003744169,0.000019375666,0.000076855766,0.61407065,0.0000074212526,0.37834725,0.006025625],"study_design_scores_gemma":[0.0004318105,0.0002597057,4.3575886e-7,0.00012023184,0.00007413691,0.0000068611453,0.000024437946,0.00002651712,0.44229987,0.000047533093,0.55636936,0.00033910884],"about_ca_topic_score_codex":0.00014632929,"about_ca_topic_score_gemma":0.0000015476206,"teacher_disagreement_score":0.27385998,"about_ca_system_score_codex":0.00012854217,"about_ca_system_score_gemma":0.00035906344,"threshold_uncertainty_score":0.999674},"labels":[],"label_agreement":null},{"id":"W2154437375","doi":"10.1016/j.pharmthera.2005.01.008","title":"Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis","year":2006,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":204,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Robarts Clinical Trials","funders":"","keywords":"Heterotrimeric G protein; Metabotropic glutamate receptor; Metabotropic glutamate receptor 1; G protein-coupled receptor; Cell biology; Metabotropic glutamate receptor 7; G protein-coupled receptor kinase; Biology; G protein; Metabotropic glutamate receptor 6; Signal transduction; Biochemistry; Receptor; Agonist","score_opus":0.03926971081452531,"score_gpt":0.33226427785816204,"score_spread":0.29299456704363674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154437375","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0026017295,0.9940337,0.0020657144,0.00002130875,0.00067071844,0.00049829466,0.000060420472,0.000018135195,0.000030000207],"genre_scores_gemma":[0.0023264366,0.9945759,0.0014999758,0.00016803358,0.0005176529,0.000044242213,0.00056595897,0.00007211718,0.00022964682],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983102,0.00035792898,0.00054916285,0.0004095028,0.0001249476,0.000248273],"domain_scores_gemma":[0.9990802,0.000046891713,0.0005091075,0.00018611205,0.00012718135,0.000050549144],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020623517,0.00034874803,0.00080136675,0.000113443646,0.00008130359,0.000017486314,0.00015328161,0.00044065958,0.00012830824],"category_scores_gemma":[0.000002896402,0.00031494562,0.00024416376,0.00012340087,0.00010341022,0.000004656643,0.00007679651,0.00016354004,0.0000067326623],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034841632,0.00006162991,0.000005993903,0.0015833869,0.00088705745,0.000001035105,0.000016298514,0.000047582264,0.76303905,0.00005781251,0.00043097016,0.23383433],"study_design_scores_gemma":[0.0002745628,0.00014297418,0.0000012420952,0.00021231387,0.0022163086,0.000009708644,0.0000035258004,0.000049967395,0.19612949,0.00003958843,0.8006779,0.00024242923],"about_ca_topic_score_codex":0.0000052673654,"about_ca_topic_score_gemma":0.0000010307442,"teacher_disagreement_score":0.8002469,"about_ca_system_score_codex":0.000025351488,"about_ca_system_score_gemma":0.00010441758,"threshold_uncertainty_score":0.99993026},"labels":[],"label_agreement":null},{"id":"W2154711995","doi":"10.1017/s1461145709990642","title":"Blockade of [11C](+)-PHNO binding in human subjects by the dopamine D3 receptor antagonist ABT-925","year":2009,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"AstraZeneca; Abbott Laboratories","keywords":"Globus pallidus; Putamen; Substantia nigra; Dopamine receptor D3; Internal medicine; Endocrinology; Striatum; 5-HT4 receptor; Chemistry; Dopamine receptor D2; Pharmacology; Receptor; Dopamine; Dopaminergic; Biology; Medicine; Basal ganglia; Agonist; Central nervous system","score_opus":0.010883409603658125,"score_gpt":0.30263413759032887,"score_spread":0.29175072798667073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2154711995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99355775,0.00056012144,0.000102882696,0.0037799613,0.0015646846,0.00010727475,0.000019633011,0.0000028433635,0.00030485995],"genre_scores_gemma":[0.99696654,0.00047716338,0.0000674339,0.0013642136,0.0008059859,0.0000023039122,0.000011703158,0.000014357297,0.00029031403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860835,0.0001913387,0.00054924376,0.00016357686,0.0003003112,0.00018715825],"domain_scores_gemma":[0.9990523,0.0000623427,0.00049738016,0.00013657365,0.00020169788,0.000049745235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053903693,0.0001403279,0.00018648984,0.000110652414,0.00007590025,0.000028122444,0.000982118,0.00007355646,0.0001417021],"category_scores_gemma":[0.000057125704,0.00009041524,0.00013564985,0.000111714544,0.00009684941,0.000009268925,0.000065546126,0.00032542596,0.0000031650047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005415763,0.00015055509,0.00017238883,0.0000017143483,0.00008331459,0.000024330411,0.00006151617,0.00014903425,0.9900621,0.000064579974,0.007236691,0.0014521815],"study_design_scores_gemma":[0.0017253016,0.0007560061,0.000646038,0.000020006919,0.000023991975,0.0002579308,0.00006937026,0.00003439948,0.97687536,0.00018107519,0.019311778,0.00009873304],"about_ca_topic_score_codex":0.000008868383,"about_ca_topic_score_gemma":0.0000030233346,"teacher_disagreement_score":0.013186749,"about_ca_system_score_codex":0.000026638196,"about_ca_system_score_gemma":0.00004444776,"threshold_uncertainty_score":0.36870265},"labels":[],"label_agreement":null},{"id":"W2155028709","doi":"10.1210/me.2007-0334","title":"Cell Growth Inhibition and Functioning of Human Somatostatin Receptor Type 2 Are Modulated by Receptor Heterodimerization","year":2008,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; McGill University; Royal Victoria Hospital","funders":"University of British Columbia","keywords":"Somatostatin receptor 2; Somatostatin receptor; Endocrinology; Biology; Internal medicine; Somatostatin; Receptor; Agonist; Acromegaly; Internalization; Cell biology; Biochemistry; Medicine","score_opus":0.008079596720328907,"score_gpt":0.20819829350834698,"score_spread":0.20011869678801808,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155028709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905324,0.0009906614,0.007918025,0.00005243293,0.0001646051,0.0001550907,0.000021296057,0.00002642488,0.00013906759],"genre_scores_gemma":[0.99723434,0.00038702818,0.0012329269,0.00012547433,0.000041352672,0.000014061048,0.0007325614,0.00003672665,0.0001955352],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988358,0.00012258023,0.00028047807,0.0003869246,0.00011227447,0.0002619113],"domain_scores_gemma":[0.9993884,0.000006140061,0.00019616212,0.00018448617,0.00016143199,0.00006336519],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000048029015,0.00017837131,0.00021017641,0.000075598255,0.0001454286,0.000008786483,0.00006996014,0.0001606136,0.000106051375],"category_scores_gemma":[0.0000429451,0.00019463812,0.000055507975,0.000118934375,0.000107785585,0.0000076573415,0.000073526564,0.00009798896,0.000008854311],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000473016,0.000055362303,0.001467714,0.000025594787,0.00003197822,0.00000647958,0.000051650826,0.000040003604,0.996429,0.00012117723,0.0016207463,0.0001029516],"study_design_scores_gemma":[0.0006537699,0.0005518494,0.0002689701,0.000013632529,0.0000127489075,0.00003556693,0.00006140419,0.000035912308,0.9970583,0.000060728587,0.0010587776,0.00018836714],"about_ca_topic_score_codex":0.0000343765,"about_ca_topic_score_gemma":0.000001218699,"teacher_disagreement_score":0.0067019374,"about_ca_system_score_codex":0.000011401856,"about_ca_system_score_gemma":0.000020902366,"threshold_uncertainty_score":0.79371125},"labels":[],"label_agreement":null},{"id":"W2155062549","doi":"10.1074/jbc.m414043200","title":"Folding Efficiency Is Rate-limiting in Dopamine D4 Receptor Biogenesis","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Limiting; Biogenesis; Dopamine; Chemistry; Folding (DSP implementation); Biophysics; Internal medicine; Neuroscience; Biology; Medicine; Biochemistry","score_opus":0.01887693390780967,"score_gpt":0.251131268354827,"score_spread":0.23225433444701735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155062549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967974,0.0016050821,0.00067734724,0.00023295968,0.00009691527,0.000046204706,0.000011036211,0.000005744476,0.00052735076],"genre_scores_gemma":[0.99483514,0.0008926757,0.0028794168,0.00025632014,0.0009506857,0.0000025234933,0.000017070357,0.000012921088,0.00015327673],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864763,0.0000555334,0.00058527134,0.00027197096,0.00013532769,0.00030427787],"domain_scores_gemma":[0.9992419,0.000039682327,0.0003245852,0.00015412709,0.000115033305,0.00012468592],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000729595,0.00018240245,0.00028032358,0.000038717266,0.000055524564,0.000026473943,0.00031361452,0.00029605647,0.00058248395],"category_scores_gemma":[0.00033580064,0.0001366577,0.00021328652,0.00013990648,0.000051785308,0.000008356794,0.00008732033,0.00020547792,0.0000069032913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093730734,0.00009317753,0.003144308,0.000011739975,0.000020413068,0.000008150871,0.00001642989,0.00011521185,0.99177253,0.00000363744,0.0002003031,0.004520341],"study_design_scores_gemma":[0.00052606437,0.0002089066,0.0003337306,0.00004585455,0.0000072871294,0.00006106884,0.000108994805,0.00006200913,0.984148,0.00001814288,0.014297816,0.0001821203],"about_ca_topic_score_codex":0.0000016776247,"about_ca_topic_score_gemma":3.7678885e-7,"teacher_disagreement_score":0.014097514,"about_ca_system_score_codex":0.00004381742,"about_ca_system_score_gemma":0.0000527196,"threshold_uncertainty_score":0.63777906},"labels":[],"label_agreement":null},{"id":"W2155119567","doi":"10.1124/jpet.104.067595","title":"Imidazoline Receptors but Not α2-Adrenoceptors Are Regulated in Spontaneously Hypertensive Rat Heart by Chronic Moxonidine Treatment","year":2004,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôtel-Dieu de Montréal","funders":"","keywords":"Moxonidine; Imidazoline receptor; Endocrinology; Receptor; Internal medicine; Agonist; Chemistry; Adrenergic receptor; Epinephrine; Biology; Medicine","score_opus":0.014763812928572947,"score_gpt":0.2855555373737548,"score_spread":0.27079172444518185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155119567","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98179597,0.016164098,0.000053500655,0.0008612527,0.0009260359,0.00017743194,0.00000887996,0.000005730862,0.0000071199365],"genre_scores_gemma":[0.993798,0.0035289393,0.00032951616,0.0016967686,0.0004433587,0.000007959083,0.000019743227,0.000029959185,0.00014575188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882483,0.00010261909,0.00042172754,0.00023655793,0.00012334918,0.00029088533],"domain_scores_gemma":[0.9994664,0.000015936213,0.00024470704,0.000081818274,0.000080311635,0.000110791414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015101083,0.0002525485,0.00038864504,0.00008099106,0.00009426104,0.000016679995,0.00011617169,0.0002099978,0.00016440648],"category_scores_gemma":[0.0000031384225,0.00020891632,0.00012755558,0.00007132843,0.000111308116,0.000012658849,0.000036438207,0.00017864877,0.0000025980492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012384885,0.00040684393,0.00006993963,0.0000044400545,0.00022653419,0.000085176354,0.00023019772,0.00071320083,0.9959636,0.0000051317247,0.0005122384,0.00054421794],"study_design_scores_gemma":[0.0049001314,0.0031351782,0.000015558857,0.000020650205,0.000069853755,0.0008129628,0.0006286644,0.00004641336,0.9742658,0.000018913828,0.01588081,0.00020505821],"about_ca_topic_score_codex":0.000019720374,"about_ca_topic_score_gemma":0.0000073794295,"teacher_disagreement_score":0.021697786,"about_ca_system_score_codex":0.00027208315,"about_ca_system_score_gemma":0.00014253074,"threshold_uncertainty_score":0.851936},"labels":[],"label_agreement":null},{"id":"W2155177235","doi":"10.1002/hbm.20392","title":"Brain region binding of the D<sub>2/3</sub> agonist [<sup>11</sup>C]‐(+)‐PHNO and the D<sub>2/3</sub> antagonist [<sup>11</sup>C]raclopride in healthy humans","year":2007,"lang":"en","type":"article","venue":"Human Brain Mapping","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Raclopride; Globus pallidus; Radioligand; Striatum; Agonist; Chemistry; Putamen; Ventral striatum; 5-HT4 receptor; Internal medicine; Endocrinology; Receptor; Dopamine; Basal ganglia; Biology; Biochemistry; Central nervous system; Medicine","score_opus":0.01600311624662741,"score_gpt":0.2462980057406197,"score_spread":0.2302948894939923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155177235","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890762,0.0007574892,0.0049301046,0.0032941892,0.00021654314,0.0011994939,0.000027513604,0.00006048106,0.0004379933],"genre_scores_gemma":[0.9953662,0.00028859806,0.00023204475,0.0028007422,0.00077172037,0.00006495065,0.00014827386,0.00013787491,0.0001895986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9945375,0.0007480666,0.0014784422,0.0012611826,0.0006412537,0.0013335729],"domain_scores_gemma":[0.99715793,0.00043028372,0.00074939843,0.0012302842,0.00016613708,0.00026594347],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0044438625,0.0007369709,0.0008439773,0.0003772584,0.0017079043,0.00023724303,0.00095340534,0.00058900757,0.000016977729],"category_scores_gemma":[0.0005578485,0.000591475,0.00047635462,0.0006714557,0.0009103116,0.000044433436,0.000611224,0.00075651426,0.000008493395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002851782,0.00010834742,0.0035125266,0.00020286856,0.00008416698,0.000031719774,0.00268795,0.0006535374,0.98330086,0.005358343,0.001890688,0.0018838266],"study_design_scores_gemma":[0.007877776,0.0005637652,0.008741912,0.00093123724,0.00009666237,0.00021362184,0.008397503,0.0019348385,0.94595134,0.0030962927,0.020575108,0.0016199268],"about_ca_topic_score_codex":0.00020120555,"about_ca_topic_score_gemma":0.0007826127,"teacher_disagreement_score":0.037349492,"about_ca_system_score_codex":0.00016572888,"about_ca_system_score_gemma":0.00020340305,"threshold_uncertainty_score":0.99965364},"labels":[],"label_agreement":null},{"id":"W2155325230","doi":"10.1124/jpet.108.144824","title":"M5 Muscarinic Receptor Knockout Mice Show Reduced Morphine-Induced Locomotion but Increased Locomotion after Cholinergic Antagonism in the Ventral Tegmental Area","year":2008,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mecamylamine; Ventral tegmental area; Muscarinic acetylcholine receptor; Knockout mouse; Chemistry; Endocrinology; Internal medicine; Dopamine; Conditioned place preference; Antagonist; Morphine; Atropine; Pharmacology; Muscarinic acetylcholine receptor M4; Neuroscience; Receptor; Biology; Dopaminergic; Medicine; Biochemistry","score_opus":0.027417889756025878,"score_gpt":0.29620294587771445,"score_spread":0.26878505612168857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155325230","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99544775,0.0028400968,0.00007142517,0.00038976362,0.0009851633,0.0002304763,0.000008257097,0.0000044779276,0.000022584554],"genre_scores_gemma":[0.99597585,0.0011092805,0.00025149624,0.001762802,0.00079687964,0.00002225001,0.000030559288,0.000020690764,0.0000301814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986341,0.00028213262,0.00042983986,0.00021070473,0.00018202125,0.00026117708],"domain_scores_gemma":[0.99949384,0.000021171021,0.00024218475,0.00009476638,0.000056292418,0.000091775546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035499095,0.00021584869,0.00023509453,0.000084365645,0.00013663355,0.000017651402,0.00020698343,0.00019211779,0.00019843149],"category_scores_gemma":[0.0000044563703,0.00016366347,0.00014299297,0.00008083189,0.00012568211,0.00002634668,0.00005097725,0.00032717673,0.0000023685614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010571632,0.0005274559,0.0003196925,0.0000052538185,0.000121188124,0.000043798766,0.0010420785,0.000042969088,0.996186,0.0000031365846,0.00030018765,0.0003510757],"study_design_scores_gemma":[0.002817144,0.0011512906,0.0011798085,0.00001321345,0.000060068396,0.00072316,0.0009912121,0.00018069672,0.99187636,0.000018065337,0.00081236556,0.00017658534],"about_ca_topic_score_codex":0.000013949701,"about_ca_topic_score_gemma":0.0000013408211,"teacher_disagreement_score":0.00430961,"about_ca_system_score_codex":0.000068025474,"about_ca_system_score_gemma":0.000093890405,"threshold_uncertainty_score":0.66740024},"labels":[],"label_agreement":null},{"id":"W2155547273","doi":"10.1124/mol.106.026716","title":"Distinct Signaling Profiles of β1 and β2 Adrenergic Receptor Ligands toward Adenylyl Cyclase and Mitogen-Activated Protein Kinase Reveals the Pluridimensionality of Efficacy","year":2006,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":286,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"GlaxoSmithKline","keywords":"Adenylyl cyclase; Receptor; Protein kinase A; Effector; Signal transduction; MAPK/ERK pathway; Intrinsic activity; Inverse agonist; G protein-coupled receptor; Functional selectivity; Ligand (biochemistry); cAMP-dependent pathway; Biology; Chemistry; Cell biology; Biochemistry; Pharmacology; Kinase; Agonist","score_opus":0.009112526610595445,"score_gpt":0.2492321039072224,"score_spread":0.24011957729662695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155547273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99530345,0.0031946057,0.0004742234,0.0002115761,0.00013226386,0.00058780436,0.000053804255,0.00001103839,0.000031250147],"genre_scores_gemma":[0.9986656,0.000055063592,0.0007450536,0.00010200548,0.0001341852,0.00006294761,0.00011197202,0.000029023697,0.00009420356],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99845606,0.00023314197,0.00044117385,0.00043286546,0.00017134075,0.00026539827],"domain_scores_gemma":[0.9992436,0.000050191953,0.0002758971,0.00019463358,0.0001498841,0.000085796346],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037342997,0.00023772923,0.00033584156,0.000053037573,0.00009541056,0.0000120150435,0.0001567167,0.00018311075,0.00011128887],"category_scores_gemma":[0.00006605995,0.00018712066,0.00010646252,0.00012269404,0.0002665951,0.000005362904,0.00017396145,0.00013487542,5.100646e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037617233,0.00012675386,0.00024092502,0.00009217796,0.00011939991,0.000010688441,0.000054870583,0.00011793736,0.9981027,0.00019415714,0.00027487366,0.00028932592],"study_design_scores_gemma":[0.0013454738,0.00033047888,0.00032484077,0.00004188085,0.00009151518,0.000013371116,0.000035661084,0.000066858265,0.99657017,0.00018710233,0.00079526776,0.00019737838],"about_ca_topic_score_codex":0.000060281403,"about_ca_topic_score_gemma":0.00000162465,"teacher_disagreement_score":0.0033621115,"about_ca_system_score_codex":0.000009604561,"about_ca_system_score_gemma":0.000071651855,"threshold_uncertainty_score":0.7630559},"labels":[],"label_agreement":null},{"id":"W2155866739","doi":"10.1161/01.hyp.38.1.56","title":"Src Is an Important Mediator of Extracellular Signal–Regulated Kinase 1/2–Dependent Growth Signaling by Angiotensin II in Smooth Muscle Cells From Resistance Arteries of Hypertensive Patients","year":2001,"lang":"en","type":"article","venue":"Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Medical Research Council Canada","keywords":"Angiotensin II; Proto-oncogene tyrosine-protein kinase Src; Vascular smooth muscle; Signal transduction; Endocrinology; Internal medicine; Extracellular; Kinase; Receptor; Phosphorylation; Chemistry; Biology; Cell biology; Medicine; Smooth muscle","score_opus":0.00880964718034054,"score_gpt":0.18913403944455442,"score_spread":0.18032439226421387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155866739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964128,0.002852035,0.00015046395,0.000050680977,0.00013481014,0.00026123243,0.00012031834,0.000008380455,0.000009276025],"genre_scores_gemma":[0.9977951,0.00048252635,0.0010500506,0.0001641333,0.000047302736,0.000006039838,0.00036722806,0.000042653,0.000044989123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99782914,0.0001167305,0.0007708394,0.00059226924,0.0003535508,0.0003374591],"domain_scores_gemma":[0.9987531,0.0000258805,0.00033812036,0.000379765,0.00038716546,0.000115974035],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024281348,0.0002721559,0.0005239122,0.00012184263,0.000058864167,0.000010340834,0.00018196719,0.00028782146,0.00009992109],"category_scores_gemma":[0.00004891402,0.0002569881,0.000117080584,0.00020157946,0.00007352961,0.000021155407,0.000082349514,0.00011698121,9.009e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034432075,0.00045286462,0.004021102,0.000015671021,0.000020372463,0.000055004966,0.00030132566,0.000061022245,0.99386954,0.000003714022,0.00042812328,0.0004269199],"study_design_scores_gemma":[0.0014283054,0.00043480366,0.0039713234,0.00014256277,0.000031217765,0.0000011881747,0.000361706,0.00073366036,0.9916829,0.00012267604,0.0007962057,0.0002934696],"about_ca_topic_score_codex":0.0005540644,"about_ca_topic_score_gemma":0.0001731404,"teacher_disagreement_score":0.0023695088,"about_ca_system_score_codex":0.0000228904,"about_ca_system_score_gemma":0.000048058282,"threshold_uncertainty_score":0.99998826},"labels":[],"label_agreement":null},{"id":"W2156304815","doi":"10.1139/y11-099","title":"Effect of inter-renal aortic coarctation-induced hypertension on function and expression of vascular α<sub>1A</sub>- and α<sub>1D</sub>-adrenoceptors","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Internal medicine; Endocrinology; Antagonist; Agonist; Aorta; Angiotensin II; Renal artery; Chemistry; Saline; Phenylephrine; Receptor; Medicine; Blood pressure; Kidney","score_opus":0.008106222117714426,"score_gpt":0.23391626747129216,"score_spread":0.22581004535357774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156304815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974767,0.0014874268,0.00016003074,0.00003074302,0.000702548,0.00012739918,0.000007950737,0.0000014512499,0.0000057677676],"genre_scores_gemma":[0.99914414,0.00035828984,0.000022250859,0.00015825761,0.00028133774,0.0000044294748,0.000015886182,0.0000140973925,0.0000013247071],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988562,0.00033888777,0.00031176745,0.00018084729,0.000060932813,0.0002513655],"domain_scores_gemma":[0.99911314,0.000096874865,0.00028170377,0.00007657906,0.00011337083,0.00031830856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040579398,0.00016831818,0.00036075083,0.00016014637,0.000100652825,0.0000041223147,0.000066535446,0.00022998496,0.00006459106],"category_scores_gemma":[0.000046119265,0.00013731902,0.0000846241,0.00005191818,0.000175478,0.000017973573,0.000026998801,0.00019882568,6.394197e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006225375,0.000026923823,0.0007809228,0.00009360512,0.00013078775,0.000002370438,0.000096657146,0.000021587895,0.99148047,0.000009532728,0.0002382424,0.006496359],"study_design_scores_gemma":[0.001296858,0.0031786733,0.0035215593,0.00005398967,0.00016804115,0.00004678161,0.000038049806,0.000049882183,0.9913574,0.00008330532,0.000088552304,0.0001169372],"about_ca_topic_score_codex":0.000043310414,"about_ca_topic_score_gemma":0.000029600202,"teacher_disagreement_score":0.006379422,"about_ca_system_score_codex":0.0000139335,"about_ca_system_score_gemma":0.00009633959,"threshold_uncertainty_score":0.55997074},"labels":[],"label_agreement":null},{"id":"W2156437245","doi":"10.1124/mol.60.1.92","title":"Dopamine D<sub>4</sub>and D<sub>2L</sub>Receptor Stimulation of the Mitogen-Activated Protein Kinase Pathway Is Dependent on<i>trans-</i>Activation of the Platelet-Derived Growth Factor Receptor","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":127,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Platelet-derived growth factor receptor; Wortmannin; Autophosphorylation; Biology; Tyrosine kinase; Chemistry; Receptor; Cell biology; Molecular biology; Protein kinase A; Signal transduction; Kinase; Biochemistry; Protein kinase B; Growth factor","score_opus":0.00963308136360346,"score_gpt":0.22664769895354178,"score_spread":0.2170146175899383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156437245","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938639,0.00018679566,0.0035090144,0.00040045078,0.000558658,0.0013407577,0.00010130057,0.000017546367,0.000021568754],"genre_scores_gemma":[0.9988193,0.00017196262,0.00009239383,0.0005243763,0.00013021611,0.00010393386,0.0000729819,0.00006149089,0.000023367229],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977166,0.00045809263,0.0005105148,0.00056303304,0.0003755127,0.00037625883],"domain_scores_gemma":[0.99876314,0.000039968018,0.00044893497,0.00037279725,0.000267411,0.00010774236],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020421059,0.0003667319,0.00034533264,0.00008688034,0.00017230594,0.000016587082,0.00035453463,0.00034303105,0.00014047931],"category_scores_gemma":[0.00008670724,0.00027422936,0.00024071654,0.00028757507,0.0001710441,0.000016125616,0.00015439434,0.00029096554,0.000003561252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007384342,0.00020337291,0.00012820937,0.00005459799,0.00020628885,0.0000029050057,0.00015537131,0.0003648057,0.9943715,0.000029448873,0.000113755545,0.0036313443],"study_design_scores_gemma":[0.002010952,0.00044401188,0.0003874769,0.00005341569,0.000044669992,0.000007362779,0.000027153974,0.0001434147,0.99553084,0.000047647092,0.001017367,0.00028569388],"about_ca_topic_score_codex":0.000020725629,"about_ca_topic_score_gemma":0.0000039954134,"teacher_disagreement_score":0.0049553695,"about_ca_system_score_codex":0.000055540673,"about_ca_system_score_gemma":0.00012594754,"threshold_uncertainty_score":0.999971},"labels":[],"label_agreement":null},{"id":"W2156786487","doi":"10.1124/mol.110.069054","title":"Differential Signaling of Cysteinyl Leukotrienes and a Novel Cysteinyl Leukotriene Receptor 2 (CysLT2) Agonist, N-Methyl-Leukotriene C4, in Calcium Reporter and β Arrestin Assays","year":2010,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Agonist; G protein-coupled receptor; Chemistry; Biology; Biochemistry","score_opus":0.010240849565149365,"score_gpt":0.2652310063006385,"score_spread":0.25499015673548914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156786487","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9747332,0.0008540199,0.022442205,0.00016130219,0.0010709706,0.0005311283,0.000044714256,0.0000254274,0.00013706327],"genre_scores_gemma":[0.9951858,0.0000984852,0.0037002086,0.00023861046,0.00035690144,0.000093769326,0.00011447313,0.000074394266,0.0001373528],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970747,0.00020715082,0.00084588316,0.00096473336,0.00027986264,0.0006276466],"domain_scores_gemma":[0.9986827,0.000075047836,0.00039222825,0.00038729954,0.00018673185,0.00027603676],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006345926,0.00045875687,0.0006457099,0.00024307339,0.00012718455,0.000049382583,0.0002853559,0.0005517474,0.00024066227],"category_scores_gemma":[0.00018456312,0.00046229197,0.00015294513,0.00023585842,0.00033659523,0.000017187669,0.00035384326,0.00045760974,0.0000018040724],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034999906,0.00017169442,0.00092187664,0.00008780617,0.00012683115,0.000085431595,0.00011935617,0.000113540125,0.99645233,0.0003250294,0.00013087656,0.0011152171],"study_design_scores_gemma":[0.003216513,0.00048578193,0.00022019638,0.000031269377,0.00011102378,0.00018416217,0.000089122586,0.0007554885,0.9903779,0.00012140213,0.003932698,0.00047446424],"about_ca_topic_score_codex":0.0001154914,"about_ca_topic_score_gemma":0.000038105805,"teacher_disagreement_score":0.020452635,"about_ca_system_score_codex":0.000025567162,"about_ca_system_score_gemma":0.00018000155,"threshold_uncertainty_score":0.99978286},"labels":[],"label_agreement":null},{"id":"W2156984021","doi":"10.1051/medsci/20122810002","title":"Métaphores, nomenclature et nouveaux paradigmes de signalisation par les récepteurs couplés aux protéines G","year":2012,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"","keywords":"Chemistry; Humanities; Molecular biology; Philosophy; Biology","score_opus":0.06885958343118306,"score_gpt":0.3423636239355319,"score_spread":0.27350404050434884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156984021","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017509958,0.9722608,0.0043161465,0.00071443466,0.0013145913,0.0012705309,0.00013780867,0.0000417623,0.002434024],"genre_scores_gemma":[0.07094046,0.9166815,0.006820175,0.0005468429,0.0023708937,0.0003537596,0.00056260056,0.000111161746,0.0016126115],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9951709,0.0005900787,0.0009721954,0.0013009601,0.00070203823,0.0012638125],"domain_scores_gemma":[0.9980086,0.00018036619,0.0007710331,0.000501129,0.00018861744,0.00035024533],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0026838346,0.0009808186,0.0011946702,0.00022943693,0.0011010537,0.00035399664,0.0011679512,0.0011488255,0.0012628915],"category_scores_gemma":[0.00022983828,0.000773876,0.00063208304,0.0006480262,0.0010897304,0.000053682656,0.00027797488,0.00058573147,0.00008186571],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016304584,0.0018567288,0.018546293,0.013136753,0.0012683154,0.00004926413,0.0017136623,0.0020968902,0.2644617,0.11110348,0.016942453,0.5686614],"study_design_scores_gemma":[0.0004261576,0.0009215014,0.00021195727,0.0019195367,0.00047401089,0.0001241287,0.0002887685,0.00015777533,0.012545765,0.0018057191,0.9799845,0.0011401327],"about_ca_topic_score_codex":0.00019532634,"about_ca_topic_score_gemma":0.00007738031,"teacher_disagreement_score":0.9630421,"about_ca_system_score_codex":0.00010273844,"about_ca_system_score_gemma":0.0014712366,"threshold_uncertainty_score":0.99965006},"labels":[],"label_agreement":null},{"id":"W2157142484","doi":"10.5206/wurjhns.2013-14.11","title":"There are No Sex-Specific Differences in Habituation and Prepulse Inhibition of Acoustic Startle Response in Sprague Dawley Rats","year":2013,"lang":"en","type":"article","venue":"Western Undergraduate Research Journal Health and Natural Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Habituation; Prepulse inhibition; Startle response; Stimulus (psychology); Psychology; Startle reaction; Audiology; Moro reflex; Developmental psychology; Neuroscience; Medicine; Schizophrenia (object-oriented programming); Cognitive psychology; Reflex","score_opus":0.04477210134874211,"score_gpt":0.34138245369862413,"score_spread":0.29661035234988203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157142484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98937017,0.0066769766,0.00007732547,0.003527764,0.000073319316,0.00026009648,0.0000023224209,0.0000017206709,0.000010324506],"genre_scores_gemma":[0.99080443,0.008818251,0.00014174073,0.00006602067,0.000056514695,0.000007816101,0.0000030060046,0.0000044411076,0.00009777465],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9978648,0.0007757427,0.00031123863,0.00026618232,0.00039927242,0.00038278732],"domain_scores_gemma":[0.99932015,0.00014317065,0.00013571772,0.00006879341,0.00014552135,0.0001866258],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029399483,0.00009408439,0.00016646028,0.00023468304,0.00024023226,0.00014813768,0.000108533844,0.00006716997,0.0000072730963],"category_scores_gemma":[0.00018826438,0.000065998,0.000018649156,0.0002512586,0.00025089466,0.000051511204,0.00007099763,0.00032587015,0.0000016036623],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000758299,0.0000891896,0.14114633,0.00013042148,0.000006016681,0.000011699022,0.000562983,0.000045544897,0.84367424,0.00004569383,0.00018161182,0.013347985],"study_design_scores_gemma":[0.0040680915,0.013187082,0.7750368,0.002976946,0.0000040306572,0.00026016939,0.015951378,0.0052621122,0.15759227,0.024252897,0.00056715944,0.0008410624],"about_ca_topic_score_codex":0.00023361619,"about_ca_topic_score_gemma":0.0005376364,"teacher_disagreement_score":0.68608195,"about_ca_system_score_codex":0.000038407838,"about_ca_system_score_gemma":0.00023873268,"threshold_uncertainty_score":0.26913205},"labels":[],"label_agreement":null},{"id":"W2157351194","doi":"10.1038/npp.2015.47","title":"Septal Glucagon-Like Peptide 1 Receptor Expression Determines Suppression of Cocaine-Induced Behavior","year":2015,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"National Health and Medical Research Council; Medical Research Council; NSW Ministry of Health; Canadian Institutes of Health Research; University of New South Wales","keywords":"Neuroscience; Biology; Conditioned place preference; Receptor; GABAergic; Glucose homeostasis; Dopamine; Cell biology; Internal medicine; Endocrinology; Inhibitory postsynaptic potential; Insulin; Medicine; Genetics","score_opus":0.030824693856835304,"score_gpt":0.31346586444911684,"score_spread":0.28264117059228155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157351194","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99462056,0.00023609122,0.00022361135,0.000051066236,0.0039880443,0.00034773917,0.000022041499,0.000030807423,0.00048003357],"genre_scores_gemma":[0.9968774,0.000091249625,0.0010951264,0.00042292924,0.0005561132,0.00008678134,0.000077672266,0.000056610173,0.000736154],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982465,0.0002485316,0.00040332906,0.0005313834,0.00022392128,0.0003463427],"domain_scores_gemma":[0.99894917,0.000023666324,0.0002202391,0.0003465651,0.00020666537,0.0002536759],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020265982,0.00025687125,0.00027954282,0.00008501861,0.00006666642,0.000012724653,0.0003411835,0.00025111245,0.00032343515],"category_scores_gemma":[0.000068037385,0.0002327033,0.00018354555,0.00011246584,0.0000688255,0.00001065027,0.00018341966,0.00018066674,0.000031373653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000618804,0.00020169427,0.00047558852,0.000014527453,0.000020910347,0.000018020659,0.000072531424,0.00002662757,0.97754633,0.0000026917446,0.01927736,0.001724881],"study_design_scores_gemma":[0.0020738218,0.0011021831,0.00030019222,0.000017584198,0.000046680252,0.00004179369,0.000069158144,0.000047074132,0.96717906,0.000008491595,0.028886547,0.00022738938],"about_ca_topic_score_codex":0.000008122555,"about_ca_topic_score_gemma":0.0000017780717,"teacher_disagreement_score":0.010367278,"about_ca_system_score_codex":0.00001306883,"about_ca_system_score_gemma":0.00008774684,"threshold_uncertainty_score":0.9489365},"labels":[],"label_agreement":null},{"id":"W2157385320","doi":"10.3109/10799893.2013.781625","title":"Measurement of G protein-coupled receptor surface expression","year":2013,"lang":"en","type":"review","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Internalization; Receptor; Cell biology; Signal transduction; Cell surface receptor; Biology; Computational biology; Receptor expression; Biochemistry","score_opus":0.0315594994868129,"score_gpt":0.2683418532723335,"score_spread":0.2367823537855206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157385320","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00957511,0.9828708,0.006019173,0.000012328093,0.0008572705,0.0006340709,0.000010445017,0.0000043473196,0.000016418497],"genre_scores_gemma":[0.0031884965,0.99238044,0.0034206596,0.0000027974122,0.0007375268,0.000015718359,0.000023965118,0.000057820445,0.00017255214],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99734974,0.00029701777,0.0012078496,0.0003243064,0.00059519924,0.00022589118],"domain_scores_gemma":[0.99772054,0.000012624733,0.0013463006,0.00017792665,0.00057289185,0.000169727],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011146064,0.00040454773,0.0012429991,0.00014143955,0.00007871513,0.000037938004,0.00022351177,0.000504793,0.0006399194],"category_scores_gemma":[0.000039204377,0.00028981682,0.0006833751,0.0001375883,0.0000683338,0.000021879325,0.000027573156,0.0003715506,0.000002827579],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007259809,0.00007293214,8.6520816e-7,0.0024863265,0.0002029665,5.619047e-7,0.000029639004,0.000018846698,0.714986,0.0000050646613,0.0003972029,0.281727],"study_design_scores_gemma":[0.0003940898,0.0010544616,1.6425655e-7,0.007690644,0.00028865357,0.00006003951,0.000076512246,0.000004186425,0.32721984,0.000017189965,0.6628899,0.00030434053],"about_ca_topic_score_codex":0.000006899198,"about_ca_topic_score_gemma":5.120461e-7,"teacher_disagreement_score":0.6624927,"about_ca_system_score_codex":0.000053017568,"about_ca_system_score_gemma":0.00026091406,"threshold_uncertainty_score":0.9999554},"labels":[],"label_agreement":null},{"id":"W2157519884","doi":"10.1083/jcb.200504167","title":"CAPRI and RASAL impose different modes of information processing on Ras due to contrasting temporal filtering of Ca2+","year":2005,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; University of California, San Diego; School of Medicine, New York University; Directorate for Biological Sciences; York University; Wellcome Trust","keywords":"Pleckstrin homology domain; Biology; Biophysics; Cell biology; GTPase; Cytosol; Second messenger system; Exocytosis; Chromosomal translocation; Membrane; Biochemistry; Signal transduction; Gene","score_opus":0.007795406163838091,"score_gpt":0.23007486263860144,"score_spread":0.22227945647476335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157519884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.982358,0.00038809006,0.016984422,0.000059956164,0.000042803757,0.00006268262,0.0000045767215,9.846245e-7,0.000098483295],"genre_scores_gemma":[0.9982102,0.00008490119,0.0015128125,0.000067731424,0.000109153436,5.5279065e-7,0.000003964455,0.000004379944,0.0000062922554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993675,0.00006243771,0.00036365917,0.00004642079,0.000057219204,0.00010281177],"domain_scores_gemma":[0.9993877,0.000028208662,0.00037925786,0.00006287496,0.00010314222,0.00003881292],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003370192,0.000078973004,0.0001855341,0.000050838415,0.000033390133,0.000005927616,0.000104558996,0.000066328095,0.0000071521645],"category_scores_gemma":[0.000043098775,0.00004821344,0.00003909364,0.000023949879,0.000036099358,0.000008160893,0.00004239217,0.00007429905,2.1565208e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027679425,0.000017708535,0.00014518607,0.000029331484,0.00001425477,1.88877e-7,0.00031485507,0.0010406716,0.98742104,0.000019288005,0.0000072379557,0.010713476],"study_design_scores_gemma":[0.0004023476,0.0007772676,0.000252159,0.00004723852,0.000014642393,0.000022495416,0.00023056692,0.00074785296,0.9972102,0.000045338074,0.00019828457,0.00005157489],"about_ca_topic_score_codex":0.0000069321773,"about_ca_topic_score_gemma":0.0000035480787,"teacher_disagreement_score":0.015852211,"about_ca_system_score_codex":0.0000073565643,"about_ca_system_score_gemma":0.000030589432,"threshold_uncertainty_score":0.19660869},"labels":[],"label_agreement":null},{"id":"W2157562973","doi":"10.1073/pnas.1936664100","title":"β-Arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors","year":2003,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":511,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Arrestin; G protein-coupled receptor; Gs alpha subunit; Adenylyl cyclase; Agonist; Cell biology; G protein; Receptor; Inverse agonist; Signal transduction; Protein kinase A; MAPK/ERK pathway; Heterotrimeric G protein; Gi alpha subunit; Biology; G protein-coupled receptor kinase; HEK 293 cells; Chemistry; Kinase; Biochemistry","score_opus":0.023784113760041928,"score_gpt":0.27703436244447655,"score_spread":0.25325024868443463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157562973","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998084,0.000021649452,0.00010828129,0.00023538613,0.000022035041,0.0004644925,0.00005826064,0.0000033048004,0.001002567],"genre_scores_gemma":[0.99715614,0.000008339492,0.002522806,0.000060519884,0.000026271082,0.000044360775,0.000007648671,0.000004447304,0.00016946135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898875,0.000008898475,0.00031296548,0.00016694346,0.0004064866,0.000115947485],"domain_scores_gemma":[0.99886096,0.00004606894,0.00061784603,0.000009569045,0.00043642623,0.000029118053],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080744695,0.000084793515,0.00012465235,0.0000601149,0.00014779351,0.000010396632,0.0002786798,0.000104304054,0.00001934412],"category_scores_gemma":[0.0019095984,0.00006264161,0.00007067063,0.0002740272,0.00028634616,0.000038054197,0.000033934444,0.00006158447,2.5283978e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033658314,0.00002763823,0.00021926918,0.00004902947,0.000016076892,1.8599694e-10,0.00006384048,0.000027329732,0.992239,0.006351534,0.0009012438,0.00007138284],"study_design_scores_gemma":[0.0002468697,0.00009919467,0.00043223856,0.000055249326,0.0000068241616,5.65135e-7,0.00021609922,0.00037966645,0.99122137,0.0064946157,0.00077732984,0.00006995209],"about_ca_topic_score_codex":0.0000035551,"about_ca_topic_score_gemma":6.313001e-8,"teacher_disagreement_score":0.0024145246,"about_ca_system_score_codex":0.000016901016,"about_ca_system_score_gemma":0.00005864213,"threshold_uncertainty_score":0.25544506},"labels":[],"label_agreement":null},{"id":"W2157599965","doi":"10.1186/1750-2187-5-16","title":"Chaperones contribute to G protein coupled receptor oligomerization, but do not participate in assembly of the G protein with the receptor signaling complex","year":2010,"lang":"en","type":"article","venue":"Journal of Molecular Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Dalhousie University; Nova Scotia Health Research Foundation; Natural Sciences and Engineering Research Council of Canada; Dalhousie Medical Research Foundation; Heart and Stroke Foundation of Canada","keywords":"Receptor; Cell biology; G protein-coupled receptor; Biology; Signal transduction; Transmembrane protein; Context (archaeology); Angiotensin II; Chaperone (clinical); Endoplasmic reticulum; Biochemistry; Medicine","score_opus":0.012090643144500658,"score_gpt":0.23879705766651768,"score_spread":0.22670641452201704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157599965","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.968588,0.00016278621,0.028667388,0.0014110134,0.00017916822,0.00096006086,0.0000146206185,0.0000057399084,0.000011224102],"genre_scores_gemma":[0.99216235,0.0000068179766,0.007047923,0.000352487,0.0002513061,0.0000671611,0.000009415896,0.000054904176,0.000047611175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974099,0.0003253751,0.00085780845,0.00031679598,0.0006621617,0.0004279728],"domain_scores_gemma":[0.9977954,0.00004232714,0.00087466266,0.0004116027,0.00071501994,0.00016098365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017041133,0.00029266556,0.00045347883,0.00011164032,0.00017663733,0.000092000606,0.000672822,0.00018474899,0.00011191774],"category_scores_gemma":[0.00040617285,0.00017765506,0.00022540538,0.00041091818,0.00011550607,0.00001948708,0.00012426013,0.00048940844,0.0000029107146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051583705,0.000082032515,0.000121209196,0.00002898449,0.00011355483,0.000008246439,0.000245876,0.00664124,0.9916938,0.00025577677,0.000022128845,0.000271314],"study_design_scores_gemma":[0.0010945041,0.0006086564,0.00008961789,0.00030257323,0.000042844305,0.000022368442,0.00030249523,0.00030112956,0.99566275,0.000038677532,0.0012849054,0.00024948668],"about_ca_topic_score_codex":0.00002591,"about_ca_topic_score_gemma":0.000021974713,"teacher_disagreement_score":0.023574376,"about_ca_system_score_codex":0.000025790981,"about_ca_system_score_gemma":0.00024249955,"threshold_uncertainty_score":0.7244563},"labels":[],"label_agreement":null},{"id":"W2157668374","doi":"10.2174/138161211798220963","title":"(Pro)renin Receptor as a New Drug Target","year":2011,"lang":"en","type":"review","venue":"Current Pharmaceutical Design","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Renin–angiotensin system; Receptor; Medicine; Pharmacology; Drug; Pathogenesis; Intracellular; Endocrinology; Internal medicine; Chemistry; Biochemistry","score_opus":0.18082313146188558,"score_gpt":0.40909323498404915,"score_spread":0.22827010352216356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157668374","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000018880469,0.95367503,0.04198881,0.000019758427,0.00246343,0.0012750785,0.000047965867,0.000058099806,0.0004699502],"genre_scores_gemma":[0.0000046563287,0.98833495,0.005726022,0.00011553175,0.0017017836,0.00018859559,0.0005796992,0.00015657679,0.0031921996],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963651,0.0006487455,0.0007974665,0.0011266652,0.00029335907,0.0007686936],"domain_scores_gemma":[0.9979584,0.000068060894,0.0003058787,0.00056885125,0.000086741165,0.0010120721],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000655769,0.0008461955,0.0012233882,0.00012456044,0.00011937487,0.00008312896,0.00083372655,0.0005208276,0.0046149795],"category_scores_gemma":[0.0002369702,0.0007056786,0.00085732056,0.00022803959,0.000089621666,0.0000080202335,0.0002898673,0.00081790896,0.0015784826],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061028255,0.00013385469,1.944443e-7,0.0015573936,0.00019423348,0.000003773208,0.000024001856,8.474017e-7,0.0014226772,0.00051748636,0.10470901,0.8913755],"study_design_scores_gemma":[0.00040149209,0.00018480857,1.3225324e-8,0.0018653969,0.00051282847,0.000026376352,0.0000027013239,0.000015070471,0.02187901,0.00034527143,0.9739486,0.00081845315],"about_ca_topic_score_codex":0.0000041991766,"about_ca_topic_score_gemma":1.2157244e-7,"teacher_disagreement_score":0.89055705,"about_ca_system_score_codex":0.000056605662,"about_ca_system_score_gemma":0.0011883989,"threshold_uncertainty_score":0.99953943},"labels":[],"label_agreement":null},{"id":"W2158001130","doi":"10.1074/mcp.m115.047951","title":"A Comprehensive Immunoreceptor Phosphotyrosine-based Signaling Network Revealed by Reciprocal Protein–Peptide Array Screening","year":2015,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo; Western University","funders":"Canadian Cancer Society Research Institute; Canada Research Chairs; Cancer Research Institute","keywords":"Interactome; SH2 domain; Computational biology; Immunoreceptor tyrosine-based activation motif; LYN; Biology; Signal transduction; Cell biology; Phosphopeptide; Phosphotyrosine-binding domain; Protein–protein interaction; Proto-oncogene tyrosine-protein kinase Src; Phosphorylation; Biochemistry","score_opus":0.01468442470340914,"score_gpt":0.2190857585881408,"score_spread":0.20440133388473167,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158001130","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5509498,0.0031242443,0.44431514,0.00008002075,0.00017514013,0.0011737804,0.00001744132,0.00005596252,0.00010849296],"genre_scores_gemma":[0.77602553,0.000020502379,0.22037375,0.000742326,0.00048757452,0.00041448703,0.001070338,0.00022239503,0.0006430948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963504,0.0003941664,0.0006996952,0.0010239081,0.00058533775,0.0009465123],"domain_scores_gemma":[0.9978875,0.000015673151,0.00038027664,0.0008070816,0.000462405,0.00044709208],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007870441,0.00063777855,0.0005551715,0.000067736735,0.00027357184,0.00017093304,0.0005875764,0.00051542255,0.000059674865],"category_scores_gemma":[0.00013176718,0.0006743632,0.0003741515,0.00031902592,0.00014312816,0.000015673008,0.00018014495,0.00047063627,0.000029329802],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005374713,0.00009123235,0.00013347635,0.000047956597,0.000131404,0.000030715895,0.000043732514,0.010955028,0.98590136,0.00005219475,0.0016406081,0.0004348163],"study_design_scores_gemma":[0.0019166613,0.000671962,0.0000025565455,0.0001582977,0.00004982278,0.0000113142105,0.000094190436,0.0013982619,0.959155,0.00021193373,0.03553,0.000799948],"about_ca_topic_score_codex":0.000058367055,"about_ca_topic_score_gemma":0.0000018951084,"teacher_disagreement_score":0.22507574,"about_ca_system_score_codex":0.00008723942,"about_ca_system_score_gemma":0.00030716823,"threshold_uncertainty_score":0.9995707},"labels":[],"label_agreement":null},{"id":"W2158091767","doi":"10.1080/10799890600923195","title":"The Active and the Inactive Form of the hAT<sub>1</sub>Receptor Have an Identical Ligand-Binding Environment: An MPA Study on a Constitutively Active Angiotensin II Receptor Mutant","year":2006,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Mutant; Receptor; Mutagenesis; G protein-coupled receptor; Ligand (biochemistry); Biochemistry; Chemistry; Angiotensin II; Angiotensin II receptor type 1; Amino acid; Biology; Molecular biology; Gene","score_opus":0.008283958031702955,"score_gpt":0.21954979397334629,"score_spread":0.21126583594164333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158091767","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969156,0.00020422802,0.0012869994,0.00033817993,0.00057465804,0.000605608,0.000042514483,0.000003824872,0.00002838674],"genre_scores_gemma":[0.99869746,0.0005864803,0.0001016918,0.00002436965,0.00051488995,0.000012988888,0.000010845841,0.000024847193,0.000026435537],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978389,0.0005035357,0.00058409997,0.000345678,0.00045893498,0.0002688121],"domain_scores_gemma":[0.99879456,0.00010800665,0.0006061822,0.00019411232,0.00017786678,0.000119273536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009767287,0.0002893706,0.0003861525,0.00007782385,0.00090370973,0.00008820786,0.00021883786,0.00017971422,0.000018636549],"category_scores_gemma":[0.000050022452,0.00015454454,0.00023467565,0.00010523216,0.0007205628,0.00008603057,0.000053726624,0.00042728422,4.7196167e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003456808,0.00040207032,0.00020740608,0.000004377107,0.00024942006,0.0000012731392,0.0026431389,0.0000930392,0.97746897,0.00040627073,0.000043273907,0.015023975],"study_design_scores_gemma":[0.0023005656,0.0035168272,0.0014096822,0.000058741458,0.00018167206,0.00006530037,0.013589996,0.000063019324,0.97697806,0.00056405144,0.001075107,0.00019694658],"about_ca_topic_score_codex":0.00003235312,"about_ca_topic_score_gemma":0.000038199756,"teacher_disagreement_score":0.014827028,"about_ca_system_score_codex":0.00007458011,"about_ca_system_score_gemma":0.00008123683,"threshold_uncertainty_score":0.6950696},"labels":[],"label_agreement":null},{"id":"W2158097683","doi":"10.18740/s43p46","title":"Social Science and Social Struggle: Understanding the Necessary Confluence of Scholarship and Political Commitment","year":2008,"lang":"en","type":"article","venue":"Socialist studies","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Politics; Praxis; Sociology; Skepticism; Scholarship; Cognitive reframing; Framing (construction); Epistemology; Ideology; Environmental ethics; Social science; Political science; Law; Social psychology","score_opus":0.10238485498213501,"score_gpt":0.3482314965251703,"score_spread":0.24584664154303532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158097683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99268156,0.0018591243,0.000115951385,0.0037871043,0.000097995995,0.00012627817,0.000017295068,0.0000067322853,0.0013079458],"genre_scores_gemma":[0.9987353,0.00022308547,0.00005212027,0.0007261268,0.00021009878,0.0000069115963,0.000002535316,0.000006790795,0.000037012658],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907464,0.00006797122,0.00014226542,0.00020503256,0.00026308617,0.00024702694],"domain_scores_gemma":[0.99961203,0.000046336158,0.00007180252,0.0000589579,0.00017586464,0.000035004367],"candidate_categories":["sts"],"consensus_categories":["sts"],"category_scores_codex":[0.00049536495,0.00010146081,0.00017077252,0.000021428155,0.0019890182,0.000028646993,0.00011867057,0.00006642865,0.0000033465574],"category_scores_gemma":[0.00017308356,0.00007839908,0.000035469337,0.00008780621,0.003024138,0.000009250193,0.00023112481,0.000086847285,1.6235555e-7],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006858812,0.000050868835,0.0152974,0.00010186286,0.00027840317,0.000004208779,0.013291335,2.0989405e-7,0.25052243,0.7174033,0.0024731376,0.0005082482],"study_design_scores_gemma":[0.0049535604,0.0012014046,0.08989962,0.00013492632,0.00043484505,0.0000914049,0.28404468,0.000027361588,0.38266665,0.22681668,0.0078015123,0.001927364],"about_ca_topic_score_codex":0.00001633776,"about_ca_topic_score_gemma":0.0000047858034,"teacher_disagreement_score":0.4905866,"about_ca_system_score_codex":0.000060346265,"about_ca_system_score_gemma":0.0001099051,"threshold_uncertainty_score":0.99968904},"labels":[],"label_agreement":null},{"id":"W2158104996","doi":"10.1111/j.1460-9568.2008.06450.x","title":"Chronic activation of the D2 dopamine autoreceptor inhibits synaptogenesis in mesencephalic dopaminergic neurons <i>in vitro</i>","year":2008,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Autoreceptor; Quinpirole; Dopamine receptor D2; Dopamine; Dopaminergic; Synaptogenesis; Neuroscience; Dopamine receptor; Dopamine receptor D1; Postsynaptic potential; Axon; Chemistry; Biology; Agonist; Receptor; Internal medicine; Medicine","score_opus":0.01678164041322637,"score_gpt":0.22408287475048833,"score_spread":0.20730123433726194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158104996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981762,0.00019554805,0.0007572378,0.00016014594,0.0004391743,0.000086120264,0.000002568563,0.0000023936243,0.00018060418],"genre_scores_gemma":[0.9991802,0.00021404769,0.0001497902,0.00016111232,0.00017037524,8.6834706e-7,8.031765e-7,0.00001870601,0.0001040848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982919,0.00043327978,0.0005070222,0.00023956323,0.000305373,0.00022285082],"domain_scores_gemma":[0.99922293,0.000020030675,0.00039599044,0.00021989607,0.00007691802,0.000064248656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058486854,0.00013316021,0.00017537967,0.00012764675,0.00007359744,0.000012090526,0.00054622884,0.000026324411,0.000006450673],"category_scores_gemma":[0.0002697727,0.00009738055,0.00011071278,0.00038315682,0.00017673608,0.000022913584,0.00012929442,0.00018561922,9.938507e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043457734,0.000049115395,0.00062221393,0.0000055369546,0.0000013178171,0.000036217236,0.000048884667,0.0030197632,0.99528205,0.000007684311,0.00002378394,0.0008599863],"study_design_scores_gemma":[0.00048347912,0.00040457043,0.037968777,0.000047687572,0.000002913329,0.00020856928,0.00001764833,0.00023668517,0.95901346,0.0000021950073,0.0015209534,0.000093074],"about_ca_topic_score_codex":0.000004302352,"about_ca_topic_score_gemma":0.0000019055035,"teacher_disagreement_score":0.03734656,"about_ca_system_score_codex":0.000028564364,"about_ca_system_score_gemma":0.00015264597,"threshold_uncertainty_score":0.39710635},"labels":[],"label_agreement":null},{"id":"W2158207659","doi":"10.1146/annurev.pharmtox.42.091701.082314","title":"Dimerization: An Emerging Concept for G Protein–Coupled Receptor Ontogeny and Function","year":2002,"lang":"en","type":"review","venue":"The Annual Review of Pharmacology and Toxicology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":577,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"G protein-coupled receptor; Receptor; Biogenesis; Function (biology); Biology; Cell biology; Ligand (biochemistry); Biophysics; Biochemistry; Computational biology; Chemistry; Gene","score_opus":0.02957683725806497,"score_gpt":0.3497590793519139,"score_spread":0.32018224209384893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158207659","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022189983,0.995458,0.0009482676,0.00021632898,0.0005283094,0.0024517328,0.00012693423,0.000010492695,0.000038045335],"genre_scores_gemma":[0.00017977372,0.9963518,0.00025340484,0.0010621657,0.00064963143,0.00068676076,0.0003999849,0.000041785366,0.000374708],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978758,0.00060467765,0.000634117,0.00051570375,0.00007848344,0.0002911978],"domain_scores_gemma":[0.9988842,0.00007971396,0.00056267827,0.00021355913,0.00017136468,0.000088511864],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00070916157,0.00035704116,0.0011679566,0.000053199197,0.00019929913,0.000008986541,0.0002488105,0.0004330721,0.0005592509],"category_scores_gemma":[0.00009578357,0.00024964326,0.00022702222,0.000109272376,0.00025572506,0.0000122345955,0.00013538323,0.00021780892,0.0000030429417],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000097449934,0.000111529785,3.1196493e-7,0.02681329,0.0006025066,0.0000010725249,0.000089146226,9.934201e-7,0.04542752,0.0009172943,0.005193546,0.9207453],"study_design_scores_gemma":[0.00041263612,0.0014619954,2.7503845e-7,0.0026270442,0.0012937788,0.00003525064,0.000036786296,0.000017753546,0.001800024,0.000042893804,0.9920109,0.00026069366],"about_ca_topic_score_codex":0.000002237302,"about_ca_topic_score_gemma":0.0000015443567,"teacher_disagreement_score":0.9868173,"about_ca_system_score_codex":0.000010921863,"about_ca_system_score_gemma":0.00010100249,"threshold_uncertainty_score":0.9999956},"labels":[],"label_agreement":null},{"id":"W2158244763","doi":"10.1152/ajpheart.00984.2001","title":"Effect of AT<sub>1</sub> receptor blockade on cardiac apoptosis in angiotensin II-induced hypertension","year":2002,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"DNA laddering; TUNEL assay; Losartan; Apoptosis; Endocrinology; Receptor; Angiotensin II; Internal medicine; Receptor antagonist; Chemistry; Biology; DNA fragmentation; Antagonist; Medicine; Programmed cell death; Biochemistry","score_opus":0.008351340379223294,"score_gpt":0.2123026666460057,"score_spread":0.2039513262667824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158244763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986427,0.000666977,6.411742e-7,0.00009229868,0.0004252761,0.00014749722,0.0000070272326,0.000005856968,0.000011736771],"genre_scores_gemma":[0.99870324,0.00046150372,0.00006119734,0.00030512465,0.0004098754,0.0000066204434,0.00001306225,0.000034062774,0.00000530378],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997843,0.0006145672,0.0005146587,0.00048126298,0.0001571822,0.0003892985],"domain_scores_gemma":[0.9988024,0.000116723764,0.00046969164,0.00034115725,0.00012315836,0.00014684301],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039700186,0.0003088984,0.0010299217,0.00017127793,0.00012038834,0.0000036243753,0.00015943176,0.00022906669,0.00003339461],"category_scores_gemma":[0.00007875605,0.00025360484,0.00038494487,0.00018671819,0.0003308826,0.000009837537,0.000114080955,0.00029814814,0.000008652585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053913856,0.00011799841,0.00033935843,0.000019878858,0.00014539823,3.253443e-7,0.00007588796,0.00013481412,0.9956397,0.0000050241665,0.00054563006,0.0024368477],"study_design_scores_gemma":[0.0008351403,0.008018559,0.03396066,0.000055665627,0.000053310585,0.000029196348,0.000052822383,0.000059474474,0.95620084,0.000024769724,0.00047193185,0.0002376194],"about_ca_topic_score_codex":0.000011421896,"about_ca_topic_score_gemma":7.525299e-7,"teacher_disagreement_score":0.039438847,"about_ca_system_score_codex":0.00003469137,"about_ca_system_score_gemma":0.000027714954,"threshold_uncertainty_score":0.9999916},"labels":[],"label_agreement":null},{"id":"W2158321076","doi":"10.1146/annurev.pharmtox.011008.145634","title":"Akt/GSK3 Signaling in the Action of Psychotropic Drugs","year":2008,"lang":"en","type":"review","venue":"The Annual Review of Pharmacology and Toxicology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":521,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Protein kinase B; Monoamine neurotransmitter; GSK-3; Dopamine receptor D2; Dopamine; Neuroscience; Pharmacology; Signal transduction; Arrestin; Dopamine receptor; Medicine; Serotonin; Receptor; Psychology; G protein-coupled receptor; Biology; Internal medicine; Cell biology","score_opus":0.03281968591974794,"score_gpt":0.3833136512447667,"score_spread":0.35049396532501875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158321076","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001738713,0.99637324,0.000024654528,0.00023947877,0.00040493478,0.00095233927,0.00003679,0.0000029167209,0.00022691865],"genre_scores_gemma":[0.0024507237,0.9954396,0.000041359912,0.0014776089,0.00030273362,0.00015214887,0.0000578754,0.000020686086,0.000057291934],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969752,0.001462748,0.00083199795,0.0003387262,0.0001281603,0.00026319647],"domain_scores_gemma":[0.99863553,0.00026961628,0.0006948055,0.00027311474,0.000095460775,0.000031464828],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009976798,0.00029912728,0.0012633558,0.000085032465,0.00008717463,0.0000027494896,0.0005725712,0.0003859609,0.0001536373],"category_scores_gemma":[0.00006698152,0.00016784531,0.00037618156,0.00022679944,0.00031822614,0.000005331966,0.00011860964,0.00044585724,0.0000042589945],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010459917,0.00031401592,0.0000033309038,0.046579324,0.00062229775,0.000015135401,0.00056375324,0.0000041343,0.025913376,0.00060067396,0.015606208,0.90967315],"study_design_scores_gemma":[0.00029336222,0.0004828834,0.0000015082271,0.0041377763,0.00056199875,0.00019428991,0.00012059185,5.389261e-7,0.004223817,0.000059562954,0.9897565,0.00016717115],"about_ca_topic_score_codex":0.0000070793794,"about_ca_topic_score_gemma":0.0000030104711,"teacher_disagreement_score":0.9741503,"about_ca_system_score_codex":0.000011746588,"about_ca_system_score_gemma":0.00017603525,"threshold_uncertainty_score":0.6844533},"labels":[],"label_agreement":null},{"id":"W2159182296","doi":"10.1152/ajplung.2000.278.6.l1138","title":"Tyrosine kinase-dependent calcium signaling in airway smooth muscle cells","year":2000,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Genistein; Tyrosine phosphorylation; Tyrosine kinase; Endocrinology; Biology; Receptor tyrosine kinase; Phosphorylation; Internal medicine; Cell biology; Phospholipase C; Signal transduction; Tyrosine-kinase inhibitor; Chemistry; Medicine","score_opus":0.004487666008252034,"score_gpt":0.21849695606433223,"score_spread":0.2140092900560802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159182296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99553806,0.0023412833,0.0015502694,0.00007417069,0.00022559268,0.00015772489,0.000009854639,0.0000089668265,0.000094092546],"genre_scores_gemma":[0.9970084,0.00068118126,0.0011544012,0.0006565144,0.0003278579,0.000008637218,0.0000399867,0.00005646122,0.00006660341],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99757063,0.00045180734,0.00064337516,0.0005758897,0.00018582368,0.00057246565],"domain_scores_gemma":[0.9988786,0.000036580295,0.00039520545,0.00036344244,0.00012093287,0.00020526774],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037081537,0.00036903025,0.0007272645,0.00015624685,0.00009187421,0.000019225923,0.00036107737,0.00019240346,0.00029701792],"category_scores_gemma":[0.000021230064,0.00033378368,0.0002856244,0.00020425864,0.00037372718,0.000014673178,0.000101605394,0.00038491783,0.000008718082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035980728,0.00015328878,0.000022816874,0.000023534658,0.00009429702,0.000038247104,0.00010093447,0.0035773413,0.9884354,0.000036780206,0.000079492995,0.0070780627],"study_design_scores_gemma":[0.0010934237,0.0016551923,0.0011626265,0.00004592315,0.000058147605,0.00002191163,0.00021823846,0.00023332945,0.9925334,0.0002535656,0.0023392932,0.00038494333],"about_ca_topic_score_codex":0.00008333107,"about_ca_topic_score_gemma":0.0000031899458,"teacher_disagreement_score":0.0066931196,"about_ca_system_score_codex":0.00003067608,"about_ca_system_score_gemma":0.00009987953,"threshold_uncertainty_score":0.9999114},"labels":[],"label_agreement":null},{"id":"W2159509638","doi":"10.1161/01.res.0000029969.39875.4b","title":"Inactivation of Enhanced Expression of G <sub>i</sub> Proteins by Pertussis Toxin Attenuates the Development of High Blood Pressure in Spontaneously Hypertensive Rats","year":2002,"lang":"en","type":"article","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Pertussis toxin; Blood pressure; Pathogenesis; Prehypertension; Endocrinology; Internal medicine; G protein; Medicine; Toxin; Spontaneously hypertensive rat; Chemistry; Receptor; Biochemistry","score_opus":0.027747591883158132,"score_gpt":0.2620479295368336,"score_spread":0.23430033765367547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159509638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99737537,0.000572632,0.0014455065,0.0000499088,0.000017067898,0.00047745285,0.000008619842,0.0000022264483,0.000051188817],"genre_scores_gemma":[0.99935955,0.000068117595,0.0003923124,0.0000058773326,0.0000207195,0.000051985287,0.000049370556,0.000011827482,0.000040214807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865663,0.000207674,0.0003531293,0.0002238439,0.0003962096,0.00016251483],"domain_scores_gemma":[0.9990543,0.00006735701,0.0001601012,0.00021889496,0.00047147254,0.00002788916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048931624,0.00008489552,0.0001649263,0.000092811264,0.00007283058,0.000007345446,0.00014266951,0.00012996214,0.000040960407],"category_scores_gemma":[0.00025870092,0.000065857166,0.00003813692,0.00021218884,0.000066229986,0.000008479124,0.000062374034,0.000108562504,8.788661e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006334749,0.00014501011,0.00018278534,0.00005915566,0.000033597895,5.9680093e-7,0.00075880846,0.0007165919,0.99437004,0.000014132424,0.00005293867,0.0036030086],"study_design_scores_gemma":[0.00033025394,0.000113205555,0.001981482,0.000097117634,0.000008640886,0.0000017144993,0.00026056875,0.0004861561,0.9965747,0.00004659418,0.000031226966,0.0000683213],"about_ca_topic_score_codex":0.00004406534,"about_ca_topic_score_gemma":0.000023175879,"teacher_disagreement_score":0.0035346872,"about_ca_system_score_codex":0.000011610539,"about_ca_system_score_gemma":0.00005676964,"threshold_uncertainty_score":0.26855773},"labels":[],"label_agreement":null},{"id":"W2159923168","doi":"10.1016/j.neuropharm.2012.10.026","title":"The serotonin receptor 7 promotes neurite outgrowth via ERK and Cdk5 signaling pathways","year":2012,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Neurite; Cyclin-dependent kinase 5; MAPK/ERK pathway; Cell biology; Biology; Signal transduction; Receptor; Agonist; Neuroscience; Protein kinase C; Biochemistry; Mitogen-activated protein kinase kinase","score_opus":0.01259001378933368,"score_gpt":0.2418879379522758,"score_spread":0.22929792416294212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159923168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950651,0.0021577538,0.00058783713,0.00028455036,0.0012805867,0.0003765314,0.000008137364,0.00003236102,0.0002071544],"genre_scores_gemma":[0.9966817,0.0005616285,0.00043939296,0.0009985913,0.0009512744,0.000074348136,0.000015587646,0.000047133723,0.00023036955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844795,0.00029343052,0.00024110734,0.00034647866,0.00011686752,0.00055414776],"domain_scores_gemma":[0.99935055,0.000094130926,0.00010815572,0.00019502273,0.00005992754,0.0001922099],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004045984,0.00021530935,0.00016269195,0.000030654675,0.00035735723,0.000042581756,0.00022038048,0.00014388694,0.00016394687],"category_scores_gemma":[0.00007779312,0.00016436404,0.00007396229,0.00007578402,0.00011444472,0.000009676315,0.00019039487,0.00022564735,0.00003199401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000092956296,0.00004485774,0.000889465,0.000011715551,0.000033145698,0.000003523225,0.00009200395,0.0000064384603,0.9927271,0.00012631566,0.0006082696,0.0053642266],"study_design_scores_gemma":[0.00043836568,0.00033955363,0.00041483552,0.0000026988544,0.000026664096,0.00004523496,0.000031099193,0.00010820199,0.9382035,0.0000512422,0.060154486,0.00018412074],"about_ca_topic_score_codex":0.000004050412,"about_ca_topic_score_gemma":9.0270976e-7,"teacher_disagreement_score":0.059546217,"about_ca_system_score_codex":0.000008071226,"about_ca_system_score_gemma":0.00002840971,"threshold_uncertainty_score":0.6702571},"labels":[],"label_agreement":null},{"id":"W2159970885","doi":"10.1111/j.1471-4159.2005.03603.x","title":"Differential regulation of corticotropin releasing factor 1α receptor endocytosis and trafficking by β‐arrestins and Rab GTPases","year":2006,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research; Hypertension Canada; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"HEK 293 cells; Endosome; Cell biology; Biology; GTPase; G protein-coupled receptor; Rab; Receptor; Endocytic cycle; Transfection; Enzyme-linked receptor; Endocytosis; Signal transduction; Cell culture; Biochemistry","score_opus":0.006061277993662087,"score_gpt":0.20713490815845348,"score_spread":0.2010736301647914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159970885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970023,0.0011408713,0.0016310445,0.000037579215,0.000101936326,0.00003915969,0.00002318346,0.0000033924725,0.000020547337],"genre_scores_gemma":[0.9981601,0.00085903,0.0005959104,0.0000110501705,0.00025765906,6.201133e-7,0.000027485865,0.000016438102,0.00007166797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911964,0.000031430132,0.000393426,0.0001681059,0.00015997766,0.000127434],"domain_scores_gemma":[0.9993033,0.000027003367,0.00041415036,0.000087372195,0.00009801654,0.00007018807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00001623673,0.00013030633,0.00020700233,0.000028117103,0.00005422033,0.00003196097,0.00007223362,0.00010195046,0.000051294675],"category_scores_gemma":[0.00009115863,0.00012050833,0.000073971416,0.000035087174,0.000056317145,0.00000890146,0.0000337671,0.00011000001,5.459094e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105314044,0.00004471568,0.0009745051,0.000056919936,0.000019890187,0.0000019861006,0.000014376678,0.000023817176,0.9962561,0.0000031664472,0.00040087654,0.0020983082],"study_design_scores_gemma":[0.0005806766,0.00018923145,0.004558307,0.00007550077,0.000031304662,0.00010184079,0.000035599787,0.00007810504,0.9934892,0.000015284497,0.00073645817,0.000108513756],"about_ca_topic_score_codex":0.0000057328707,"about_ca_topic_score_gemma":4.2063576e-7,"teacher_disagreement_score":0.003583802,"about_ca_system_score_codex":0.000008721521,"about_ca_system_score_gemma":0.000028632187,"threshold_uncertainty_score":0.49141872},"labels":[],"label_agreement":null},{"id":"W2160753998","doi":"10.1074/jbc.m111.277723","title":"Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC)","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Biophysics; Dynamics (music); Cell biology; Biochemistry; Biology; Physics","score_opus":0.01535340690473109,"score_gpt":0.21769575593226057,"score_spread":0.20234234902752948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160753998","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99902195,0.00028155567,0.00012509288,0.000047562866,0.000010797817,0.000093383904,0.000009708531,0.0000011509966,0.00040880402],"genre_scores_gemma":[0.999625,0.00010265934,0.00016592753,0.00002232338,0.00003843179,0.000004301401,0.000014329679,0.0000040148816,0.00002299629],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993803,0.000077330995,0.00026536817,0.00009204027,0.00009923772,0.00008571206],"domain_scores_gemma":[0.99941087,0.000016239628,0.0003811826,0.000103728344,0.00006602006,0.000021936085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031098232,0.00008047374,0.00013755956,0.000010473386,0.000023749692,0.0000041684807,0.00015954976,0.0001753035,0.00003429365],"category_scores_gemma":[0.0001304209,0.000041839754,0.00007746316,0.00007297113,0.00007872087,0.0000048516795,0.00004308148,0.00014501555,4.4827104e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015961961,0.00009125623,0.0006531567,0.000021032478,0.000013809941,2.0745533e-7,0.00008812014,8.060409e-7,0.9981533,0.000014058339,0.000019720854,0.0007849091],"study_design_scores_gemma":[0.00027414793,0.00015292536,0.0010572852,0.000056555295,0.000005612547,0.000013072046,0.0003595573,0.000012271864,0.9974065,0.00046277474,0.00014849234,0.00005080466],"about_ca_topic_score_codex":0.000011961693,"about_ca_topic_score_gemma":0.0000018306379,"teacher_disagreement_score":0.0007468024,"about_ca_system_score_codex":0.000016116684,"about_ca_system_score_gemma":0.000018903916,"threshold_uncertainty_score":0.17061757},"labels":[],"label_agreement":null},{"id":"W2161031758","doi":"10.1124/mol.114.093450","title":"Label-Free Monitoring of μ-Opioid Receptor–Mediated Signaling","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Quebec Rehabilitation Research Network; Université de Montréal; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Opioid; Receptor; Cell biology; Pharmacology; Biology; Biochemistry","score_opus":0.009961288683444971,"score_gpt":0.2641422670028574,"score_spread":0.25418097831941244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161031758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97531396,0.000986122,0.021761963,0.000107070766,0.0010946094,0.00018979202,0.000014043976,0.000030889223,0.00050155533],"genre_scores_gemma":[0.9904085,0.00014243842,0.008258223,0.00038007658,0.00054014346,0.00003627105,0.00007172345,0.00005135993,0.00011129246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842364,0.00023426807,0.00035121973,0.0004115832,0.0001948918,0.00038438977],"domain_scores_gemma":[0.99914503,0.000041127838,0.00017014924,0.000361096,0.00014936342,0.00013325403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041537965,0.00022000422,0.00027660196,0.000084125495,0.00007076286,0.0000115855155,0.00045452945,0.0002315705,0.0003787851],"category_scores_gemma":[0.00015235874,0.00023191674,0.00012199217,0.00014224206,0.00007822486,0.0000042974348,0.00021183617,0.00016114514,0.000023464656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081803446,0.00007277867,0.00049157423,0.00003324307,0.00011350975,0.0000042899883,0.00003624108,0.00028383802,0.9960872,0.00016652995,0.0010543666,0.001574633],"study_design_scores_gemma":[0.0013987775,0.0003981155,0.000027669923,0.000016315056,0.000041570678,0.000004920924,0.000027952578,0.0002465245,0.9771804,0.00020168167,0.020226872,0.00022915564],"about_ca_topic_score_codex":0.000009635311,"about_ca_topic_score_gemma":4.209033e-7,"teacher_disagreement_score":0.019172506,"about_ca_system_score_codex":0.000015996458,"about_ca_system_score_gemma":0.000054322845,"threshold_uncertainty_score":0.945729},"labels":[],"label_agreement":null},{"id":"W2161296684","doi":"10.1016/s0166-2236(03)00033-x","title":"In search of a better mouse test","year":2003,"lang":"en","type":"review","venue":"Trends in Neurosciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":153,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health","keywords":"Task (project management); Test (biology); Reliability (semiconductor); Psychology; Simple (philosophy); Computer science; Cognitive psychology; Biology; Ecology","score_opus":0.059890576544753965,"score_gpt":0.3584269092241219,"score_spread":0.29853633267936797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161296684","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0065988875,0.9917946,0.000013406717,0.000014245585,0.00046289357,0.0001338305,0.000033065568,0.0000030888234,0.00094599184],"genre_scores_gemma":[0.00084510684,0.99603164,0.0001936076,0.00006471665,0.000047511156,0.00002073244,0.000014852057,0.000017850518,0.0027639666],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985801,0.00014460195,0.00037732022,0.00046220853,0.00017665155,0.00025914062],"domain_scores_gemma":[0.99957806,0.000032501903,0.00010548253,0.00023442069,0.000011688845,0.000037844224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034053758,0.00018528308,0.0004913441,0.0003579514,0.000019839486,0.000018650975,0.00038395572,0.00016722638,0.000086145985],"category_scores_gemma":[0.00005905208,0.00014538883,0.000143909,0.000671265,0.00011060701,0.0000039359606,0.000080456346,0.00017537107,0.0000021248752],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000039032807,0.00028239816,0.0002855191,0.0011892545,0.0000059581143,0.000030342542,0.00003921852,0.000017592849,0.071556196,0.00005440352,0.0004525045,0.92608273],"study_design_scores_gemma":[0.00018644845,0.00040291683,0.000013975155,0.00061211945,0.000016578058,0.000021612197,0.0000136407325,0.000016711394,0.022859769,0.000014029703,0.9755081,0.00033410138],"about_ca_topic_score_codex":0.000017392145,"about_ca_topic_score_gemma":0.000023125544,"teacher_disagreement_score":0.9750556,"about_ca_system_score_codex":0.00000953105,"about_ca_system_score_gemma":0.00008476484,"threshold_uncertainty_score":0.59287846},"labels":[],"label_agreement":null},{"id":"W2161491285","doi":"10.1073/pnas.1106277108","title":"Protein kinase C epsilon modulates nicotine consumption and dopamine reward signals in the nucleus accumbens","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Alcohol Abuse and Alcoholism; Canadian Institutes of Health Research","keywords":"Nucleus accumbens; Nicotine; Dopamine; Addiction; Nicotinic agonist; Conditioned place preference; Striatum; Medium spiny neuron; Pharmacology; Protein kinase C; Neuroscience; Cholinergic; Chemistry; Endocrinology; Internal medicine; Biology; Receptor; Medicine; Kinase; Biochemistry","score_opus":0.05783999513270611,"score_gpt":0.2906637925620966,"score_spread":0.23282379742939052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161491285","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99870753,0.00021185176,0.0000029016483,0.00031337552,0.0000065128743,0.00020731644,0.0000062014865,0.0000020153655,0.0005422632],"genre_scores_gemma":[0.9979251,0.00004923371,0.0018456486,0.00010173065,0.000028106642,0.000012356307,2.9207757e-7,0.0000028175052,0.000034725264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918556,0.000010826982,0.00019540882,0.00017913588,0.0003281515,0.00010090786],"domain_scores_gemma":[0.99967027,0.000015544334,0.0001950587,0.000008922898,0.00009388065,0.00001632607],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001145011,0.00006877814,0.00008148902,0.000050684717,0.00008524205,0.000013993799,0.00036417358,0.0000698985,0.000015295618],"category_scores_gemma":[0.00019094282,0.000040029892,0.000033400334,0.00015443662,0.0003048032,0.0000204631,0.00008647184,0.00007479996,3.3837782e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020530608,0.00002864181,0.0038061764,0.000023180686,0.0000045984693,4.4733883e-9,0.0001176879,0.000014818782,0.99134463,0.004379737,0.000023922605,0.0002360642],"study_design_scores_gemma":[0.0001348991,0.00012300683,0.015751818,0.00005005339,0.0000044354397,0.0000048217616,0.000144313,0.00027798058,0.9732201,0.010175916,0.00005884317,0.00005382553],"about_ca_topic_score_codex":0.000009727841,"about_ca_topic_score_gemma":2.2406188e-7,"teacher_disagreement_score":0.018124549,"about_ca_system_score_codex":0.000004339271,"about_ca_system_score_gemma":0.000009846127,"threshold_uncertainty_score":0.16323715},"labels":[],"label_agreement":null},{"id":"W2161758034","doi":"10.1186/1471-2105-8-177","title":"Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base","year":2007,"lang":"en","type":"editorial","venue":"BMC Bioinformatics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute on Drug Abuse; National Institutes of Health","keywords":"G protein-coupled receptor; Ontology; Context (archaeology); Computer science; Computational biology; Knowledge base; Data science; Knowledge management; Biology; Receptor; World Wide Web; Biochemistry","score_opus":0.020055085445667805,"score_gpt":0.28881668647521375,"score_spread":0.26876160102954594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161758034","genre_codex":"methods","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0037299448,0.0009680607,0.644574,0.000010996566,0.34703586,0.0024772072,0.00045662592,0.000052086918,0.0006952622],"genre_scores_gemma":[0.00042484156,0.0007306736,0.40854517,0.00010840745,0.57003504,0.00057307864,0.014903354,0.00020070374,0.004478742],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981027,0.000037169117,0.00072152086,0.00035736526,0.00029403766,0.0004871977],"domain_scores_gemma":[0.99847174,0.000074532036,0.00047091432,0.00036660171,0.00046020487,0.00015598981],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0008634322,0.0003893609,0.0004152591,0.00013987906,0.00015522864,0.00007630582,0.00024148251,0.0013367457,0.000035935333],"category_scores_gemma":[0.0010222107,0.00037146805,0.00014579805,0.00009178762,0.0000728595,0.0000131754805,0.0001468303,0.00022545396,0.00001728566],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006678544,0.00013404676,0.000009999502,0.0030694131,0.00020788051,5.1873457e-7,0.00044113598,0.000019439221,0.2072692,0.00019121186,0.78170156,0.0062877387],"study_design_scores_gemma":[0.001858784,0.0009101103,0.0000011505523,0.00021045115,0.00008380403,0.0000021067565,0.00019656173,0.012059108,0.05309153,0.000056262266,0.9308879,0.00064226333],"about_ca_topic_score_codex":0.000008652631,"about_ca_topic_score_gemma":0.000055883465,"teacher_disagreement_score":0.23602879,"about_ca_system_score_codex":0.000054092267,"about_ca_system_score_gemma":0.00048795543,"threshold_uncertainty_score":0.9999597},"labels":[],"label_agreement":null},{"id":"W2161809826","doi":"10.1124/mol.108.048074","title":"Binding of Orthosteric Ligands to the Allosteric Site of the M2 Muscarinic Cholinergic Receptor","year":2008,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Allosteric regulation; Oxotremorine; Chemistry; Muscarinic acetylcholine receptor; Stereochemistry; Agonist; Muscarinic acetylcholine receptor M2; Ligand (biochemistry); Antagonist; Receptor; Biochemistry","score_opus":0.0115841327389137,"score_gpt":0.25107359960490094,"score_spread":0.23948946686598724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161809826","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966006,0.00055122474,0.0010134134,0.00045534977,0.00080753356,0.00035998828,0.00002286755,0.0000067873175,0.00018222957],"genre_scores_gemma":[0.99752164,0.00018555947,0.0003263295,0.0012864176,0.00016190934,0.000038939765,0.000024960416,0.000030234485,0.00042399182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870867,0.00015860716,0.0003606711,0.00030783,0.00018551163,0.00027871956],"domain_scores_gemma":[0.99919754,0.000017545697,0.000206881,0.00039131392,0.00011173752,0.000074987125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002459783,0.00017799225,0.00024056819,0.00006163394,0.00011579745,0.000004746606,0.00046355222,0.00013111596,0.00021154397],"category_scores_gemma":[0.000036705183,0.000118205826,0.00022949389,0.00033673758,0.00012070851,0.0000030058802,0.00038397755,0.00013575799,0.000015507649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008143212,0.000050065646,0.00071836595,0.000015084304,0.00008853508,0.0000049702808,0.00020498871,0.0012021817,0.9956006,0.000013863307,0.0016842757,0.00033566114],"study_design_scores_gemma":[0.00049410114,0.00030353878,0.00052602554,0.000010485388,0.000049890958,0.000036270165,0.000029963632,0.000057135363,0.980222,0.0000032959167,0.018136809,0.00013050166],"about_ca_topic_score_codex":0.000015286607,"about_ca_topic_score_gemma":0.000003706576,"teacher_disagreement_score":0.016452534,"about_ca_system_score_codex":0.000011866625,"about_ca_system_score_gemma":0.00008342493,"threshold_uncertainty_score":0.48202938},"labels":[],"label_agreement":null},{"id":"W2162109316","doi":"10.1016/j.cell.2013.01.008","title":"The Dynamic Process of β2-Adrenergic Receptor Activation","year":2013,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":809,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences","keywords":"Biology; Process (computing); Receptor; Adrenergic receptor; Cell biology; Computational biology; Genetics","score_opus":0.004019403899192247,"score_gpt":0.21345379587142108,"score_spread":0.20943439197222882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162109316","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99631035,0.0002069624,0.001594151,0.00006131816,0.00010840462,0.000113376314,0.0000011811284,0.00000437753,0.0015998472],"genre_scores_gemma":[0.9974421,0.00011030271,0.00022876874,0.00003778622,0.00005157361,0.000023897335,0.000031504667,0.0000100347725,0.0020640052],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99959147,0.000018170711,0.00010549665,0.00011519303,0.0000653964,0.000104257044],"domain_scores_gemma":[0.9996698,0.000008149005,0.00007120071,0.00014482574,0.000081606195,0.00002442913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006788436,0.00006030185,0.00005128577,0.000009304269,0.000061019728,0.000015008652,0.00011927957,0.00006278342,0.00015099603],"category_scores_gemma":[0.00001559913,0.000041283656,0.00003672689,0.000039978546,0.000023759683,0.0000027135784,0.00002157867,0.00003441871,0.000019999665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006915028,0.000013518372,0.00001671774,0.000010608831,0.0000050704925,1.0393724e-8,0.00002653379,0.000069533824,0.9972707,0.000025736854,0.0005644471,0.0019902126],"study_design_scores_gemma":[0.000102339756,0.000065508604,0.000061841405,0.000005318298,0.0000022921004,1.7519395e-7,0.00016715615,0.00026677235,0.9945804,0.00025824548,0.0044332813,0.000056709887],"about_ca_topic_score_codex":0.0000114771565,"about_ca_topic_score_gemma":0.0000017078639,"teacher_disagreement_score":0.003868834,"about_ca_system_score_codex":0.0000044188973,"about_ca_system_score_gemma":0.000024232835,"threshold_uncertainty_score":0.16834986},"labels":[],"label_agreement":null},{"id":"W2162439863","doi":"10.1111/j.1747-0285.2012.01390.x","title":"Comparison of Dynamics of Extracellular Accesses to the β<sub>1</sub> and β<sub>2</sub> Adrenoceptors Binding Sites Uncovers the Potential of Kinetic Basis of Antagonist Selectivity","year":2012,"lang":"en","type":"article","venue":"Chemical Biology & Drug Design","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Queen's University; Queen's University Belfast; Royal Society","keywords":"Chemistry; Molecular dynamics; Selectivity; Ligand (biochemistry); Biophysics; Extracellular; Antagonist; Functional selectivity; Receptor; Hydrogen bond; Stereochemistry; G protein-coupled receptor; Molecule; Biochemistry; Computational chemistry; Biology","score_opus":0.014424913599862891,"score_gpt":0.2564674108209572,"score_spread":0.2420424972210943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162439863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9796673,0.001809164,0.017937258,0.00007487183,0.00013209018,0.00029212685,0.0000718214,0.0000053655845,0.000010009728],"genre_scores_gemma":[0.9987158,0.00028489446,0.0007535834,0.000016683192,0.000091916445,0.000012340088,0.00010167578,0.000020915764,0.0000021503558],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99844635,0.00024898758,0.00051741494,0.0003092552,0.00014524857,0.00033274415],"domain_scores_gemma":[0.99878585,0.00024060952,0.0004275963,0.00030661302,0.00015194525,0.00008735581],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006680398,0.00022903208,0.00048622678,0.000059178696,0.00008092772,0.00000829248,0.00036190308,0.0002561271,0.000009339887],"category_scores_gemma":[0.00021034475,0.00015684888,0.0001571588,0.00023350943,0.0004692775,0.0000091595875,0.00019924046,0.00016118117,7.5526646e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020518473,0.00015343528,0.008833811,0.00006841019,0.00013106997,1.293776e-7,0.00017597027,0.00019936799,0.98684734,0.000087286855,0.00013850222,0.0031594997],"study_design_scores_gemma":[0.00024188386,0.00022459979,0.00031001095,0.000025955134,0.00012248094,0.000004298867,0.0003248779,0.0003516077,0.99812907,0.00007368562,0.000033283042,0.0001582647],"about_ca_topic_score_codex":0.000020669802,"about_ca_topic_score_gemma":0.000007914968,"teacher_disagreement_score":0.019048547,"about_ca_system_score_codex":0.000019632875,"about_ca_system_score_gemma":0.000056305365,"threshold_uncertainty_score":0.6396112},"labels":[],"label_agreement":null},{"id":"W2162622185","doi":"10.1186/1756-6606-3-22","title":"Transactivation of PDGFRβ by dopamine D4 receptor does not require PDGFRβ dimerization","year":2010,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Transactivation; Platelet-derived growth factor receptor; Phosphorylation; Cell biology; Receptor tyrosine kinase; Receptor Protein-Tyrosine Kinases; Signal transduction; Cancer research; Biology; Receptor; G protein-coupled receptor; Chemistry; Growth factor; Biochemistry; Transcription factor","score_opus":0.0031274752494550454,"score_gpt":0.21388058322257925,"score_spread":0.2107531079731242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162622185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84114957,0.00007883764,0.15726227,0.0006586138,0.00030516388,0.00019883775,0.000069908085,0.000017796894,0.00025898305],"genre_scores_gemma":[0.9941198,0.000025981677,0.0034734097,0.0004946248,0.00011953933,0.000023854771,0.0005869924,0.000046746616,0.0011090279],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987787,0.00008259517,0.00030443768,0.00038848934,0.00022423969,0.00022153788],"domain_scores_gemma":[0.99928087,0.000016318043,0.00015488012,0.00035866065,0.00010675122,0.00008254535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002770339,0.00019166816,0.00018415853,0.000053250293,0.000065472894,0.000023311075,0.00019516918,0.0002590254,0.0004100836],"category_scores_gemma":[0.00015867308,0.00016807446,0.00012427231,0.00012364006,0.000072586656,0.000012775631,0.000031103868,0.00014546233,0.0000053957738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005742525,0.00005975217,0.00003292857,0.000023623672,0.000037410206,9.990995e-7,0.000045138484,0.000028236993,0.9912421,0.0004430742,0.0003964143,0.0076328926],"study_design_scores_gemma":[0.00045335802,0.00016931385,0.000024390114,0.000013077473,0.000011944022,0.0000025321574,0.000034413784,0.00010578897,0.98565525,0.00010628082,0.013203692,0.00021993917],"about_ca_topic_score_codex":0.000028602506,"about_ca_topic_score_gemma":0.000010955534,"teacher_disagreement_score":0.15378885,"about_ca_system_score_codex":0.000007047341,"about_ca_system_score_gemma":0.000041495507,"threshold_uncertainty_score":0.68538773},"labels":[],"label_agreement":null},{"id":"W2162738633","doi":"10.1139/jpn.0423","title":"Impact of substance P receptor antagonism on the serotonin and norepinephrine systems: relevance to the antidepressant/anxiolytic response","year":2004,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University; Royal Ottawa Mental Health Centre; Mental Health Research Canada; University of Ottawa","funders":"","keywords":"Anxiolytic; Antidepressant; Pharmacology; Serotonin; Substance P; 5-HT receptor; Antagonism; Norepinephrine; Autoreceptor; Receptor; Medicine; Internal medicine; Chemistry; Hippocampus; Neuropeptide; Dopamine","score_opus":0.01301014333406788,"score_gpt":0.26943512216569393,"score_spread":0.25642497883162607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162738633","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945872,0.0012787242,0.0010573673,0.0021710694,0.00071360666,0.00017052692,0.00001318682,0.0000016421227,0.000006687625],"genre_scores_gemma":[0.99762183,0.0014376771,0.00029143077,0.00045249332,0.00015832046,0.0000027175486,1.9489518e-7,0.000008039289,0.000027267475],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902683,0.00013314564,0.00028447038,0.00019879783,0.00019940315,0.0001573588],"domain_scores_gemma":[0.99926853,0.000056985406,0.00027563964,0.00023227258,0.00007612818,0.00009046178],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00086134596,0.00011648879,0.00014838697,0.00004148098,0.00016913126,0.000047069527,0.00027605827,0.000040472234,0.0000022703673],"category_scores_gemma":[0.0002065909,0.00005956449,0.000075212134,0.00016301367,0.0001212137,0.000012968668,0.000030476778,0.00014630752,4.0445292e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008561417,0.000040151823,0.002344886,0.00001090755,0.0000075990497,0.0000020312084,0.00008296603,0.002974605,0.99297893,0.00039607112,0.00023104505,0.00007467225],"study_design_scores_gemma":[0.0015858023,0.009820163,0.095560364,0.0006012938,0.000034942543,0.00088056584,0.0003396083,0.00022109102,0.88578844,0.00046697338,0.004343285,0.00035747988],"about_ca_topic_score_codex":0.0000074786694,"about_ca_topic_score_gemma":0.000003450952,"teacher_disagreement_score":0.10719049,"about_ca_system_score_codex":0.000008302104,"about_ca_system_score_gemma":0.000115312236,"threshold_uncertainty_score":0.24289693},"labels":[],"label_agreement":null},{"id":"W2162987557","doi":"10.1111/j.1460-9568.2007.05627.x","title":"PGD<sub>2</sub> DP1 receptor protects brain from ischemia‐reperfusion injury","year":2007,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Aging; National Institutes of Health","keywords":"Agonist; Excitotoxicity; Neuroprotection; Ischemia; Glutamate receptor; Cerebral blood flow; Medicine; Pharmacology; Middle cerebral artery; Receptor; Brain ischemia; Reperfusion injury; In vivo; Anesthesia; Internal medicine; Biology","score_opus":0.011008031856903694,"score_gpt":0.23307504877753998,"score_spread":0.2220670169206363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2162987557","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9742608,0.00016408753,0.023919381,0.000181556,0.0009794967,0.00009798238,0.00000694653,0.000009735411,0.00037999064],"genre_scores_gemma":[0.9959506,0.0001312867,0.0017297211,0.0012307301,0.0008200495,4.0553297e-7,0.000003319066,0.00003513611,0.00009875456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998197,0.00024264064,0.00048532974,0.00036258943,0.00038846696,0.00032398346],"domain_scores_gemma":[0.9989245,0.000026944033,0.00040181758,0.00025861574,0.0001455572,0.00024256566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018220128,0.00017681356,0.00015975471,0.00008485429,0.00015449537,0.00007076536,0.00054608687,0.00005087872,0.000021676466],"category_scores_gemma":[0.0006647309,0.00014970911,0.0001372457,0.00019779742,0.00010678523,0.000022304705,0.00018763187,0.00029631238,0.000021598016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014047568,0.00003978032,0.00003200644,0.0000029916591,0.0000030881968,0.00008025929,0.000051450974,0.000020418642,0.9823012,0.0000051104935,0.0015335742,0.015789676],"study_design_scores_gemma":[0.00029703786,0.0009792525,0.00075175095,0.000048366426,0.0000045411116,0.00007096297,0.00003187199,0.00001741819,0.97119135,0.000014127967,0.026426407,0.00016692268],"about_ca_topic_score_codex":0.0000010434625,"about_ca_topic_score_gemma":5.20044e-7,"teacher_disagreement_score":0.024892833,"about_ca_system_score_codex":0.0000146281845,"about_ca_system_score_gemma":0.00007028214,"threshold_uncertainty_score":0.61049604},"labels":[],"label_agreement":null},{"id":"W2163352150","doi":"10.1016/s0031-6997(24)01478-9","title":"Evolving Concepts in G Protein-Coupled Receptor Endocytosis: The Role in Receptor Desensitization and Signaling","year":2001,"lang":"en","type":"review","venue":"Pharmacological Reviews","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1815,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Heterotrimeric G protein; G protein-coupled receptor; G protein-coupled receptor kinase; Cell biology; Rhodopsin-like receptors; G protein; Biology; Internalization; Endocytosis; Arrestin; Homologous desensitization; Signal transduction; Receptor; Desensitization (medicine); Biochemistry; Metabotropic receptor; Agonist","score_opus":0.05013473914298514,"score_gpt":0.35868539450236997,"score_spread":0.3085506553593848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163352150","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0024108235,0.99324644,0.00021886667,0.00003190834,0.00018024349,0.0037478916,0.00001219419,0.000015564432,0.00013607378],"genre_scores_gemma":[0.001926011,0.9946744,0.0008650857,0.00020159298,0.00047998404,0.0014675574,0.00019728713,0.000052600473,0.00013549063],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9956606,0.0015344208,0.0012313066,0.00084494095,0.00019063508,0.00053808047],"domain_scores_gemma":[0.99885744,0.00014730253,0.00054449344,0.00025283228,0.00006279753,0.00013511049],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019597493,0.0005726348,0.0015800791,0.00011016951,0.00011484725,0.00007805694,0.00040037523,0.00048334966,0.00084381114],"category_scores_gemma":[0.0006620699,0.0003591402,0.0003653625,0.00052060204,0.000090933136,0.000012848093,0.00022656618,0.00065618084,0.000053633034],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030625215,0.000085419735,0.000012851541,0.0013758005,0.00005140521,0.000009756403,0.000042525484,0.00001099733,0.19383925,0.000032684904,0.00031764692,0.80419105],"study_design_scores_gemma":[0.00038548492,0.00012159996,5.5504654e-7,0.004621975,0.0001404851,0.000015252054,0.000037250622,0.00013079621,0.005749376,0.00003735833,0.98831517,0.000444728],"about_ca_topic_score_codex":0.000017643371,"about_ca_topic_score_gemma":0.000011211643,"teacher_disagreement_score":0.9879975,"about_ca_system_score_codex":0.00011706048,"about_ca_system_score_gemma":0.00011882658,"threshold_uncertainty_score":0.99988604},"labels":[],"label_agreement":null},{"id":"W2163498324","doi":"10.1161/01.hyp.0000200748.73303.a6","title":"Regulator of G-Protein Signaling-2 as a Candidate Gene","year":2006,"lang":"en","type":"letter","venue":"Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"Regulator; Regulator of G protein signaling; Gene; Biology; Genetics; Signal transduction; Medicine; Cell biology; Computational biology; G protein; GTPase-activating protein","score_opus":0.0098862242591767,"score_gpt":0.20200459988080247,"score_spread":0.19211837562162576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163498324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97797227,0.0032443532,0.000935431,0.015951209,0.00058610784,0.00056390284,0.000116066156,0.000034749763,0.0005959193],"genre_scores_gemma":[0.68030256,0.00018499079,0.007020025,0.27418205,0.0088212285,0.00008281662,0.008365956,0.00039935226,0.020641048],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982978,0.000083590756,0.0003835704,0.00056695036,0.0003316331,0.00033643006],"domain_scores_gemma":[0.9988932,0.000008386304,0.00026077198,0.0005771034,0.00021110896,0.000049414626],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001413188,0.00033191685,0.0004429379,0.00008680848,0.000069077614,0.00001976762,0.00023266806,0.0010692311,0.00014432233],"category_scores_gemma":[0.000029839679,0.0002934122,0.00025263577,0.000072550785,0.000054751858,0.0000020609164,0.00010735537,0.00036399523,0.000030832656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002060041,0.000012973768,0.0000024158182,0.00004272642,0.000038439783,0.000066340755,0.0000022805618,0.00001567753,0.6756468,0.000004249904,0.32399336,0.00015418357],"study_design_scores_gemma":[0.00023620047,0.00018948216,0.0000025995344,0.00008920193,0.000042782645,0.000043802025,0.0000025779048,0.000021027754,0.66297215,0.00015564043,0.3359993,0.00024520038],"about_ca_topic_score_codex":0.00030527473,"about_ca_topic_score_gemma":0.0000050536974,"teacher_disagreement_score":0.29766974,"about_ca_system_score_codex":0.000014770427,"about_ca_system_score_gemma":0.00011615579,"threshold_uncertainty_score":0.9999518},"labels":[],"label_agreement":null},{"id":"W2163586931","doi":"10.1101/lm.54803","title":"Mitral Cell β<sub>1</sub> and 5-HT<sub>2A</sub> Receptor Colocalization and cAMP Coregulation: A New Model of Norepinephrine-Induced Learning in the Olfactory Bulb","year":2003,"lang":"en","type":"article","venue":"Learning & Memory","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Olfactory bulb; Internal medicine; Endocrinology; Autoreceptor; Colocalization; Chemistry; Neuroscience; Cyclic adenosine monophosphate; Serotonergic; Dopamine; Receptor; Serotonin; Biology; Medicine; Central nervous system","score_opus":0.014849217525593218,"score_gpt":0.21086930684015942,"score_spread":0.19602008931456621,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163586931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898002,0.0007706818,0.008836475,0.000053516203,0.00008565833,0.00024587676,0.0000016533359,0.000018807988,0.00018712589],"genre_scores_gemma":[0.99854624,0.00035232693,0.0006409757,0.00011703346,0.00009979969,0.000012228806,0.000058615027,0.000037472222,0.00013527744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847466,0.0003235647,0.00032133833,0.00040877826,0.00019925975,0.0002723771],"domain_scores_gemma":[0.9993737,0.00006143968,0.00021341386,0.00017983402,0.000076370125,0.00009524266],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005490026,0.00021954243,0.00023570568,0.000079241174,0.00016781582,0.000039560728,0.00010043892,0.00021960115,0.000016401844],"category_scores_gemma":[0.00026189815,0.00020027407,0.0000774795,0.00014092658,0.00006286722,0.000015581434,0.00004898205,0.00033507164,0.0000023637854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056291734,0.000027110866,0.0021153048,0.000039319806,0.000016571292,0.0000013901915,0.00091075106,0.044195116,0.9481292,0.000079104946,0.00006947063,0.0043604006],"study_design_scores_gemma":[0.00085180893,0.0002647929,0.0011884384,0.000040717056,0.000026532723,0.000010436457,0.0006368922,0.011105901,0.9852133,0.000083794366,0.00033570483,0.00024167499],"about_ca_topic_score_codex":0.000022708764,"about_ca_topic_score_gemma":0.000023957262,"teacher_disagreement_score":0.037084136,"about_ca_system_score_codex":0.00001906518,"about_ca_system_score_gemma":0.00013470408,"threshold_uncertainty_score":0.8166939},"labels":[],"label_agreement":null},{"id":"W2163594140","doi":"10.1016/j.neulet.2008.08.005","title":"Genetic association between the dopamine D3 gene polymorphism (Ser9Gly) and schizophrenia in Japanese populations: Evidence from a case–control study and meta-analysis","year":2008,"lang":"en","type":"review","venue":"Neuroscience Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Allele; Genotype; Internal medicine; Population; Genetics; Polymorphism (computer science); Case-control study; Psychosis; Biology; Psychology; Medicine; Psychiatry; Gene","score_opus":0.08367233958230855,"score_gpt":0.31587459447758076,"score_spread":0.23220225489527221,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163594140","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.38684505,0.6118379,0.00027926866,0.00019227815,0.000067201916,0.0006610052,0.000111720205,0.0000053833523,1.6796238e-7],"genre_scores_gemma":[0.417123,0.58155143,0.00030144333,0.0006262099,0.00018111484,0.00013817646,0.000021131937,0.000027911366,0.000029576076],"study_design_codex":"bench_or_experimental","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99690306,0.0008322717,0.00059565343,0.0009877412,0.00037494677,0.00030630437],"domain_scores_gemma":[0.9986658,0.00022649631,0.00047009328,0.00051657425,0.00003044856,0.00009057708],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00049987785,0.0003879901,0.0013182373,0.00022257272,0.0002687032,0.00015026191,0.00035304108,0.0001759219,0.000010636817],"category_scores_gemma":[0.00021415844,0.00026332098,0.00045873833,0.0006389901,0.00009565558,0.000018611336,0.00014872434,0.0002668869,9.58519e-7],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023909868,0.0009716032,0.17534807,0.0015082138,0.12565416,0.0073944177,0.0045524286,0.0041316366,0.35064247,0.0000058671585,0.00063039747,0.32892165],"study_design_scores_gemma":[0.0032778995,0.0014770714,0.10790821,0.00030321718,0.8645573,0.0019501573,0.00026471677,0.0013034847,0.00083578995,0.000035478224,0.013732058,0.0043545756],"about_ca_topic_score_codex":0.00075815746,"about_ca_topic_score_gemma":0.00022408194,"teacher_disagreement_score":0.73890316,"about_ca_system_score_codex":0.000037151047,"about_ca_system_score_gemma":0.00004283278,"threshold_uncertainty_score":0.9999819},"labels":[],"label_agreement":null},{"id":"W2164039705","doi":"10.1016/j.neuroscience.2005.06.003","title":"Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor–G protein coupling and Gβγ signaling","year":2005,"lang":"en","type":"article","venue":"Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":176,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Adenylyl cyclase; Opioid; Chemistry; (+)-Naloxone; Pharmacology; Hyperalgesia; μ-opioid receptor; Opioidergic; Morphine; Opioid receptor; Excitatory postsynaptic potential; Internal medicine; Endocrinology; Receptor; Medicine; Nociception; Biochemistry","score_opus":0.01094318281487311,"score_gpt":0.233908697908112,"score_spread":0.2229655150932389,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164039705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976349,0.0010006238,0.00068000954,0.00011442036,0.00016877793,0.0003213293,0.000019315094,0.000021507567,0.00003911153],"genre_scores_gemma":[0.99749136,0.0006655929,0.0010460785,0.00037753934,0.00012950509,0.000043213768,0.000014718973,0.000020271857,0.00021172552],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839044,0.00004818363,0.00022370943,0.0006772378,0.0002491148,0.00041133474],"domain_scores_gemma":[0.9995016,0.000028554135,0.00011041943,0.00017593379,0.00005793022,0.00012555577],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040037723,0.00020431705,0.00019570114,0.00007326667,0.00019410171,0.00011836407,0.00022683253,0.00013802886,0.00002790755],"category_scores_gemma":[0.00027799865,0.00020241948,0.000025577363,0.00021106326,0.00014351337,0.0000297906,0.00009651988,0.00017427826,0.0000015236723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031125226,0.000044978642,0.0025504758,0.000025593241,0.0000015814512,0.000003762983,0.00010141537,0.00057743746,0.9953989,0.000020261268,0.000014676474,0.0012297898],"study_design_scores_gemma":[0.00043470334,0.0002074735,0.002259555,0.000102817365,0.000003791428,0.000008095001,0.000055802444,0.0032607631,0.99153984,0.000027543125,0.0018509775,0.00024863862],"about_ca_topic_score_codex":0.000023543154,"about_ca_topic_score_gemma":0.00009810547,"teacher_disagreement_score":0.003859063,"about_ca_system_score_codex":0.000015568196,"about_ca_system_score_gemma":0.000055920893,"threshold_uncertainty_score":0.82544273},"labels":[],"label_agreement":null},{"id":"W2164978844","doi":"10.1038/ncomms6897","title":"Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":201,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"FP7 Ideas: European Research Council; Laboratory Directed Research and Development; National Institute of Neurological Disorders and Stroke; National Institute of Nursing Research; National Institute on Deafness and Other Communication Disorders; National Human Genome Research Institute; Biomedical Research Council; Wake Forest School of Medicine; National Heart, Lung, and Blood Institute; Kaiser Foundation Research Institute; National Institutes of Health; Diabetesforeningen; H. Lundbeck A/S; Hjartavernd; Novo Nordisk Foundation Center for Basic Metabolic Research; Harokopio University; Medical Research Council; Uppsala Universitet; Deutsche Krebshilfe; NHLBI Division of Intramural Research; National Institute on Aging; Helsefonden; National Center for Research Resources; National and Kapodistrian University of Athens; Stockholms Läns Landsting; Centre for Medical Systems Biology; Novo Nordisk; Karolinska Institutet; Tore Nilsons Stiftelse för Medicinsk Forskning; Hjärt-Lungfonden; Ministero della Salute; Fondazione Cariplo; Chief Scientist Office, Scottish Government Health and Social Care Directorate; British Heart Foundation; Bundesministerium für Bildung und Forschung; ZonMw; National Science Foundation; Fondation Leducq; National Medical Research Council; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; University of Glasgow; Russian Foundation for Basic Research; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; University of Exeter; Diabetes UK; National Eye Institute; National Institute for Health and Care Research; Swedish e-Science Research Centre; Cedars-Sinai Medical Center; Scottish Government; National Cancer Institute; Lundbeckfonden; Donald W. Reynolds Foundation; Eli Lilly and Company; University of Alabama; Imperial College Healthcare NHS Trust; Wellcome Trust; University of Alabama at Birmingham; National Center for Advancing Translational Sciences; Università degli Studi di Verona; Magnus Bergvalls Stiftelse; Hjerteforeningen; National Institute on Minority Health and Health Disparities; AstraZeneca; University of Aberdeen; European Commission; Augustinus Fonden; Compagnia di San Paolo; Vetenskapsrådet; University of Minnesota; Wake Forest University; Northwestern University; Sanofi; Imperial College London; Research to Prevent Blindness; University of California, San Francisco; GlaxoSmithKline; National Institute of Diabetes and Digestive and Kidney Diseases; Knut och Alice Wallenbergs Stiftelse; Scottish Funding Council; Stiftelsen för Gamla Tjänarinnor; Erasmus Universiteit Rotterdam; Johns Hopkins University; Chinese Society of Clinical Oncology; Amgen; Erasmus Medisch Centrum; U.S. Environmental Protection Agency; University of Dundee; Andrea and Charles Bronfman Philanthropies","keywords":"Exome; Type 2 diabetes; Exome sequencing; Diabetes mellitus; Medicine; Genetics; Mutation; Bioinformatics; Endocrinology; Internal medicine; Biology; Gene","score_opus":0.017683726300747347,"score_gpt":0.2619570376297991,"score_spread":0.24427331132905175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164978844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866674,0.012043989,0.000050544717,0.00040158766,0.00005921211,0.00012367741,0.000021146647,0.000015645935,0.00061680784],"genre_scores_gemma":[0.99247694,0.0004859867,0.0065722982,0.00017543981,0.000040180417,0.000008552284,0.00018222452,0.0000137401485,0.000044631262],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999354,0.000111020294,0.000110652785,0.00020093287,0.00008095383,0.00014244109],"domain_scores_gemma":[0.99895525,0.000038595557,0.00007119566,0.0006276518,0.00021130736,0.00009600605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032778582,0.00010397438,0.000111198504,0.000020932717,0.00016608418,0.00004196716,0.0002487269,0.00021662148,0.0000055412706],"category_scores_gemma":[0.0003321387,0.000087623215,0.000014860776,0.00009358715,0.0000856311,0.000008841939,0.00024170145,0.00028566297,0.0000012238918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032547665,0.00010832113,0.08923843,0.00002292779,0.00009615539,8.889394e-7,0.00032815753,0.000004465648,0.9044828,0.0015713663,0.0003981762,0.0037157908],"study_design_scores_gemma":[0.0066530476,0.0033424105,0.27049935,0.0005169273,0.00038145963,0.00007781719,0.002824324,0.0021929506,0.6706216,0.012584807,0.027602158,0.0027031766],"about_ca_topic_score_codex":0.0000114111635,"about_ca_topic_score_gemma":0.00020331038,"teacher_disagreement_score":0.2338612,"about_ca_system_score_codex":0.000013536252,"about_ca_system_score_gemma":0.00006238079,"threshold_uncertainty_score":0.3573171},"labels":[],"label_agreement":null},{"id":"W2165022068","doi":"10.1111/j.1749-6632.2009.04451.x","title":"Timing of the Functional Diversification of α‐ and β‐Adrenoceptors in Fish and Other Vertebrates","year":2009,"lang":"en","type":"article","venue":"Annals of the New York Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Genomics; University of Ottawa","funders":"","keywords":"Gene duplication; Biology; Vertebrate; Phylogenetic tree; Evolutionary biology; Diversification (marketing strategy); Fish <Actinopterygii>; Functional divergence; Genome; Phylogenetics; Gene; Genetics; Gene family; Fishery","score_opus":0.07427404515702625,"score_gpt":0.2977281469256299,"score_spread":0.22345410176860364,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165022068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971116,0.0006416026,0.000017112072,0.0020553526,0.000019742005,0.00004627955,0.000004137315,4.4573656e-7,0.00010372401],"genre_scores_gemma":[0.9992116,0.00012200329,0.00012796614,0.00044910252,0.000017807632,1.9484337e-7,1.8634452e-7,0.0000010882703,0.000070016984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995577,0.00002476534,0.00013595943,0.00009954852,0.00012247733,0.000059560658],"domain_scores_gemma":[0.9997611,0.000014176089,0.0001577371,0.00003741781,0.00001544437,0.0000141107375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029289428,0.000040396037,0.000076064716,0.000024053898,0.000043461427,0.0000031457507,0.0001735445,0.000051755855,0.00001231418],"category_scores_gemma":[0.00003653368,0.000024133864,0.000033505654,0.00012126889,0.00024753768,0.0000061180604,0.000044162647,0.000032532313,2.6446205e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015041852,0.00001125349,0.012231259,0.000006976626,0.000006064451,1.3054638e-9,0.00016874477,0.00013884227,0.9830338,0.00064702943,0.0011100048,0.002631032],"study_design_scores_gemma":[0.000079501246,0.00007155634,0.06020253,0.00004285728,0.0000039305646,3.8503998e-7,0.0001830899,0.00012226717,0.9367528,0.0022199308,0.0002943578,0.000026819775],"about_ca_topic_score_codex":0.00003678472,"about_ca_topic_score_gemma":0.0000028755694,"teacher_disagreement_score":0.04797127,"about_ca_system_score_codex":6.1804224e-7,"about_ca_system_score_gemma":0.000017926612,"threshold_uncertainty_score":0.09841504},"labels":[],"label_agreement":null},{"id":"W2165726219","doi":"10.1073/pnas.1216304109","title":"Conformation of receptor-bound visual arrestin","year":2012,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Eye Institute; National Institute of Mental Health","keywords":"Arrestin; Rhodopsin; Tetramer; Biophysics; Crystallography; Chemistry; Binding site; Stereochemistry; Electron paramagnetic resonance; Receptor; Biology; G protein-coupled receptor; Physics; Biochemistry; Nuclear magnetic resonance","score_opus":0.03059086543745859,"score_gpt":0.3094089452460269,"score_spread":0.2788180798085683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165726219","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99695677,0.00019667181,0.000012629636,0.00013800517,0.0000349519,0.000068783884,0.0000053184926,0.0000016174303,0.002585275],"genre_scores_gemma":[0.99843055,0.000030465593,0.0012896833,0.000062142535,0.000118973294,0.000002605622,5.7926457e-7,0.0000020653788,0.000062962026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991636,0.0000040658306,0.00021834401,0.00007926719,0.00043658796,0.000098135715],"domain_scores_gemma":[0.99935687,0.000014504295,0.00042335337,0.0000042249444,0.00017801835,0.000023005085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009600593,0.00005006454,0.000074697746,0.000045989374,0.00006922181,0.0000049348337,0.0002560336,0.000068956826,0.00002562474],"category_scores_gemma":[0.0003029638,0.000034461817,0.000047777765,0.00016878954,0.00025425365,0.00003200809,0.00006698796,0.000044813012,7.3035955e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009486352,0.000020318972,0.0031711073,0.00002272852,0.00000636221,4.8768403e-11,0.00007040634,0.00001937343,0.9855482,0.010489583,0.00038922273,0.00025322585],"study_design_scores_gemma":[0.00007412883,0.00005391395,0.0053469087,0.000025123074,0.0000037224072,0.0000013498459,0.00015632788,0.000121218174,0.9918976,0.0015910139,0.00068796513,0.000040773106],"about_ca_topic_score_codex":0.0000018333519,"about_ca_topic_score_gemma":8.3678175e-9,"teacher_disagreement_score":0.008898569,"about_ca_system_score_codex":0.0000055858004,"about_ca_system_score_gemma":0.000018866125,"threshold_uncertainty_score":0.1405312},"labels":[],"label_agreement":null},{"id":"W2165775221","doi":"10.1038/nature14656","title":"Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser","year":2015,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":827,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Common Fund; SLAC National Accelerator Laboratory; National Center for Research Resources; National Eye Institute; Michigan Technology Tri-Corridor; National Institute of Diabetes and Digestive and Kidney Diseases; Office of Science; National University of Defense Technology; Ministry of Science and Technology of the People's Republic of China; National Cancer Institute; University of Toronto; National Institute of General Medical Sciences; Bundesministerium für Bildung und Forschung; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; U.S. Department of Energy; Helmholtz-Gemeinschaft; Deutsche Forschungsgemeinschaft; Brain Research Foundation; Science Foundation Ireland; National Science Foundation","keywords":"Rhodopsin; Arrestin; G protein-coupled receptor; Helix (gastropod); Transmembrane domain; Protein structure; Biophysics; Biology; Femtosecond; Transmembrane protein; Crystallography; Chemistry; Signal transduction; Cell biology; Laser; Receptor; Biochemistry; Physics; Optics","score_opus":0.007440442685890206,"score_gpt":0.24727383012213072,"score_spread":0.23983338743624052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2165775221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99674714,0.0014128031,0.00049659,0.00013348839,0.00044036828,0.00011481783,0.0001688408,0.0000071759573,0.00047877507],"genre_scores_gemma":[0.9954223,0.00000473126,0.002271212,0.0007428447,0.00026080557,0.0000018520228,0.00019609228,0.000019884243,0.0010802732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923813,0.00003339637,0.00013341996,0.00025042344,0.00017168077,0.00017294777],"domain_scores_gemma":[0.9994437,0.0000059662952,0.00005703108,0.00021874928,0.00012491846,0.00014960209],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000102594975,0.00012897019,0.00013618745,0.000026705367,0.000028695697,0.000021609427,0.00017648212,0.000810472,0.00015221069],"category_scores_gemma":[0.00012819827,0.00011135841,0.00005008996,0.00008219537,0.000021565133,0.0000030307096,0.0000632987,0.00040662856,0.0000038338626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006255869,0.000014167257,0.0001343769,0.000008053777,0.000017978029,0.0000011975839,0.000055828197,0.00013818538,0.92724186,0.00003670131,0.07201288,0.00027619652],"study_design_scores_gemma":[0.00033072912,0.00018187218,0.000071432456,0.000008992377,0.000006724511,0.000004305337,0.00008734881,0.000007401488,0.87438476,0.000224746,0.12456008,0.00013160222],"about_ca_topic_score_codex":0.0000092776645,"about_ca_topic_score_gemma":0.000024759049,"teacher_disagreement_score":0.052857112,"about_ca_system_score_codex":0.000010414311,"about_ca_system_score_gemma":0.00006809296,"threshold_uncertainty_score":0.6251102},"labels":[],"label_agreement":null},{"id":"W2166733596","doi":"10.1152/ajpheart.00142.2002","title":"Increased expression of protein kinase C isoforms in heart failure due to myocardial infarction","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Isozyme; Protein kinase C; Cytosol; Internal medicine; Myocardial infarction; Endocrinology; Enzyme; Gene isoform; Chemistry; Medicine; Biochemistry; Gene","score_opus":0.005322342002603911,"score_gpt":0.22003840681169082,"score_spread":0.2147160648090869,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166733596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99932265,0.00021612676,0.00004028871,0.000074350195,0.00013762794,0.00018920355,0.000004451587,0.0000036469385,0.000011660406],"genre_scores_gemma":[0.99753976,0.000017615257,0.0017674024,0.00042878743,0.00019843635,0.000015356332,0.000008997993,0.000020537733,0.0000031057873],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983424,0.00040890052,0.00047436968,0.00034662697,0.00012149499,0.00030618545],"domain_scores_gemma":[0.99909747,0.000026357888,0.00031993032,0.00025336145,0.00013943107,0.00016346984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039304444,0.00020491981,0.0006429219,0.0001634061,0.00006452077,0.000005309264,0.00012449456,0.00015088556,0.00005379648],"category_scores_gemma":[0.00010140715,0.00017329014,0.00018711764,0.0001884101,0.00024124196,0.000016274598,0.000053180956,0.0002283958,0.0000026411115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002912692,0.00009030634,0.0011539463,0.000017746033,0.00003918646,2.6171077e-7,0.00007505694,0.00024457122,0.9977371,0.0000702153,0.00014610251,0.00013422986],"study_design_scores_gemma":[0.0007285849,0.0019029287,0.22644792,0.000057716545,0.000013668912,0.00006974652,0.00041417853,0.0000059185545,0.7664097,0.0006722708,0.0030737524,0.00020359507],"about_ca_topic_score_codex":0.000044064407,"about_ca_topic_score_gemma":0.0000045192514,"teacher_disagreement_score":0.2313274,"about_ca_system_score_codex":0.000018883497,"about_ca_system_score_gemma":0.00012942404,"threshold_uncertainty_score":0.70665675},"labels":[],"label_agreement":null},{"id":"W2167365725","doi":"10.1158/1055-9965.108.14.1","title":"Expression of the Epidermal Growth Factor Seven-Transmembrane Member CD97 Correlates with Grading and Staging in Human Oral Squamous Cell Carcinomas","year":2005,"lang":"en","type":"article","venue":"Cancer Epidemiology Biomarkers & Prevention","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Immunostaining; Biology; Pathology; Epidermal growth factor; Immunohistochemistry; Grading (engineering); Cancer research; Cell culture; Molecular biology; Medicine","score_opus":0.024539319735412495,"score_gpt":0.29230819714582174,"score_spread":0.2677688774104092,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167365725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99076194,0.004476269,0.0039261407,0.00029612822,0.00014265311,0.00031855985,0.000012494212,0.000008951601,0.000056880614],"genre_scores_gemma":[0.9978265,0.00021875754,0.0014821173,0.000111417416,0.0000788759,0.000041653828,0.000043853106,0.00002415288,0.00017265545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811184,0.00055869704,0.00047620383,0.00044232493,0.00007983832,0.00033107147],"domain_scores_gemma":[0.9992756,0.000088760484,0.00031112,0.00020958167,0.000046424197,0.00006851404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073043717,0.0002106668,0.00033812714,0.00006507754,0.00012237736,0.0000054838365,0.0001534657,0.00023140869,0.00006413344],"category_scores_gemma":[0.00005740308,0.00015057404,0.000119292265,0.0000932237,0.00015699248,0.000018737825,0.000071091104,0.00016205436,2.5848738e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012633551,0.000035297093,0.2880451,0.000066062916,0.00003005273,6.32428e-7,0.00013409388,0.0005401198,0.70993197,0.000055994347,0.00011373897,0.00092062406],"study_design_scores_gemma":[0.0016244899,0.00022268407,0.075518824,0.00022565296,0.00006580593,0.000009175944,0.00015090725,0.0008408028,0.9201586,0.0006441526,0.0002565507,0.000282346],"about_ca_topic_score_codex":0.00023461666,"about_ca_topic_score_gemma":0.00035121458,"teacher_disagreement_score":0.21252628,"about_ca_system_score_codex":0.000042987383,"about_ca_system_score_gemma":0.000052729643,"threshold_uncertainty_score":0.61402315},"labels":[],"label_agreement":null},{"id":"W2167487237","doi":"10.1158/1541-7786.mcr-08-0578","title":"β-Arrestin/Ral Signaling Regulates Lysophosphatidic Acid–Mediated Migration and Invasion of Human Breast Tumor Cells","year":2009,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":138,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children’s Health Research Institute; Western University","funders":"","keywords":"Lysophosphatidic acid; Cell migration; Cancer research; Biology; Metastasis; Ectopic expression; Cancer cell; Gene knockdown; Cell biology; Cell; Cancer; Receptor; Cell culture","score_opus":0.022549769238531345,"score_gpt":0.3108297296958961,"score_spread":0.28827996045736476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167487237","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99501574,0.0040169917,0.0003574725,0.00020272583,0.000045506793,0.00027003547,0.000024150442,0.000010688117,0.000056685643],"genre_scores_gemma":[0.9988936,0.00024875512,0.0004398778,0.00009658336,0.00009814673,0.000025131236,0.000107838474,0.000023966439,0.00006605609],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99830246,0.00018370095,0.0002687039,0.00042704385,0.00044863738,0.00036945211],"domain_scores_gemma":[0.9992017,0.00001531706,0.00009179585,0.00027046108,0.00028433173,0.00013636968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00061783096,0.00015780378,0.00018954958,0.00012382251,0.00016764837,0.000050129893,0.00019390725,0.00012547875,0.00009052918],"category_scores_gemma":[0.000054926582,0.00015097023,0.000070450435,0.0002525716,0.0001137522,0.00000829406,0.000087173066,0.00017857213,0.0000024492613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000092951006,0.000043095897,0.00038675638,0.0000328799,0.000021764847,0.000015095563,0.00006994979,0.00012040897,0.9969511,0.000103472186,0.00016143205,0.0020011005],"study_design_scores_gemma":[0.00044527723,0.0005253386,0.0006816082,0.00010162925,0.000010599569,0.000008918535,0.000069263246,0.0001961308,0.9971702,0.0004558965,0.00017800381,0.0001571498],"about_ca_topic_score_codex":0.00033914077,"about_ca_topic_score_gemma":0.00004496384,"teacher_disagreement_score":0.0038779015,"about_ca_system_score_codex":0.000027937624,"about_ca_system_score_gemma":0.00011743639,"threshold_uncertainty_score":0.61563873},"labels":[],"label_agreement":null},{"id":"W2167896883","doi":"10.1186/1471-2202-11-33","title":"Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence","year":2010,"lang":"en","type":"article","venue":"BMC Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse; National Institute of Mental Health; Canadian Institutes of Health Research; National Institutes of Health; Pennsylvania Department of Health; Heart and Stroke Foundation of Canada","keywords":"Wnt signaling pathway; Opioid; μ-opioid receptor; Opioid receptor; Cell biology; Neurogenesis; Agonist; Colocalization; Neuroscience; Receptor; Chemistry; Biology; Pharmacology; Signal transduction; Biochemistry","score_opus":0.015415362287061262,"score_gpt":0.2609440637780506,"score_spread":0.24552870149098932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167896883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9079076,0.0000138819905,0.090508565,0.000118033415,0.001039654,0.00032154968,0.000026390331,0.000008185667,0.000056114433],"genre_scores_gemma":[0.99639714,0.000016348844,0.0030088085,0.00014457057,0.00016593374,0.000058906084,0.000012377137,0.000011909878,0.00018398717],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991466,0.000027692913,0.00016070051,0.00035813797,0.0001391287,0.00016775797],"domain_scores_gemma":[0.99931306,0.000015102518,0.00014990082,0.0003281392,0.00014024209,0.000053572843],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014869365,0.000101300735,0.00007713104,0.00002353861,0.00021477886,0.00003923742,0.00035237055,0.0000713265,0.000018397837],"category_scores_gemma":[0.0001344296,0.000071607756,0.00007311084,0.00013737816,0.0001386628,0.000015020529,0.00009768097,0.00011154868,0.0000011620214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003679811,0.000026836004,0.00085599563,0.000011570862,9.970444e-7,3.6438347e-8,0.0000182639,0.00018338242,0.9977027,0.0006711744,0.000056077628,0.00043612253],"study_design_scores_gemma":[0.00017701215,0.00018301459,0.0041600126,0.000013201368,0.0000073798587,0.00002688929,0.00003537434,0.00043884674,0.9912957,0.00013768945,0.0034259867,0.00009887021],"about_ca_topic_score_codex":0.0000070736655,"about_ca_topic_score_gemma":0.000050645962,"teacher_disagreement_score":0.08848953,"about_ca_system_score_codex":0.000005331648,"about_ca_system_score_gemma":0.00014039979,"threshold_uncertainty_score":0.29200795},"labels":[],"label_agreement":null},{"id":"W2168015727","doi":"10.1523/jneurosci.1508-04.2004","title":"Long-Lasting Rescue of Age-Associated Deficits in Cognition and the CNS Cholinergic Phenotype by a Partial Agonist Peptidomimetic Ligand of TrkA","year":2004,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Tropomyosin receptor kinase A; Cholinergic; Agonist; Partial agonist; Cholinergic neuron; Neuroscience; Low-affinity nerve growth factor receptor; Receptor; Chemistry; Pharmacology; Biology; Nerve growth factor; Biochemistry","score_opus":0.014081374620678974,"score_gpt":0.24469034620821897,"score_spread":0.23060897158754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168015727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976649,0.0003514829,0.0016905131,0.00007821262,0.00011972595,0.00006598261,0.0000044858566,8.0856256e-7,0.000023832135],"genre_scores_gemma":[0.99955237,0.00020618209,0.00011196772,0.00007483301,0.00003576453,7.80244e-7,0.0000013150242,0.0000055369587,0.000011261634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999126,0.00007561298,0.00036955634,0.00011923947,0.00018550748,0.00012404956],"domain_scores_gemma":[0.9994131,0.000029778077,0.0003528245,0.000064785,0.00009971708,0.000039847127],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005669843,0.00007183614,0.0001813873,0.000043218846,0.000057902253,0.000020962963,0.00013862192,0.000048617894,0.0000010786905],"category_scores_gemma":[0.0005724999,0.00005021711,0.000060930866,0.00016062526,0.00021454468,0.000009097448,0.000037410733,0.00011055287,6.07301e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017672387,0.000068952104,0.00018288783,0.000007744787,0.000003675385,0.0000070170368,0.000092660695,0.0021600262,0.9971127,0.000029291878,0.000004739871,0.00015356696],"study_design_scores_gemma":[0.0028358484,0.00066315715,0.003596795,0.00010851812,0.00002793257,0.00005441748,0.00005554494,0.00046612916,0.9918957,0.00021383443,0.000013518643,0.00006864161],"about_ca_topic_score_codex":0.000017582965,"about_ca_topic_score_gemma":0.000014289355,"teacher_disagreement_score":0.005217051,"about_ca_system_score_codex":0.0000069070225,"about_ca_system_score_gemma":0.000068523084,"threshold_uncertainty_score":0.20477943},"labels":[],"label_agreement":null},{"id":"W2168223794","doi":"10.1002/jcp.22297","title":"TNFAIP8: A new effector for Galpha(i) coupling to reduce cell death and induce cell transformation","year":2010,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Cell biology; Effector; Tumor necrosis factor alpha; Immunoprecipitation; Biology; Cell; Chemistry; Cell culture; Biochemistry; Endocrinology; Genetics","score_opus":0.009736065954776496,"score_gpt":0.24413385577752822,"score_spread":0.23439778982275172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168223794","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94839466,0.00036233774,0.050258227,0.00008674645,0.00058723585,0.00023858654,0.0000050720328,0.000003212456,0.00006393033],"genre_scores_gemma":[0.9913888,0.00006982407,0.007240498,0.00011797391,0.0009989437,0.0000057968878,0.000021954016,0.000023724653,0.0001324734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991376,0.00002809857,0.00032939212,0.0001888667,0.00009168607,0.00022435043],"domain_scores_gemma":[0.99927497,0.0000334414,0.00021960273,0.00013723574,0.00013997345,0.00019474911],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033801456,0.00015240375,0.00026139605,0.00006972193,0.00007201555,0.000022546476,0.00016399361,0.0002104749,0.00003206302],"category_scores_gemma":[0.000039783525,0.00013096993,0.00014117823,0.000045670455,0.000017519145,0.000011180327,0.000027404743,0.00021405908,0.0000034950995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025806713,0.000042674557,0.0000075968533,0.000048421727,0.000019022018,0.000001322386,0.00013220118,0.00026300942,0.99790543,0.000049916853,0.00038358258,0.0008887725],"study_design_scores_gemma":[0.0011036681,0.0011278368,0.00009762291,0.000013323937,0.00003636163,0.000024326859,0.000052151394,0.00033908748,0.98760366,0.0002591457,0.009194862,0.00014792109],"about_ca_topic_score_codex":0.0000058988344,"about_ca_topic_score_gemma":0.0000019419485,"teacher_disagreement_score":0.04301773,"about_ca_system_score_codex":0.0000074193163,"about_ca_system_score_gemma":0.00010929457,"threshold_uncertainty_score":0.5340799},"labels":[],"label_agreement":null},{"id":"W2168448982","doi":"10.1517/14728222.6.2.185","title":"Novel G-protein-coupled receptor genes expressed in the brain: continued discovery of important therapeutic targets","year":2002,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Targets","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Receptor; Drug discovery; Biology; Rhodopsin-like receptors; Signal transduction; Neuroscience; Computational biology; Class C GPCR; Neurotransmitter receptor; Metabotropic receptor; Bioinformatics; Cell biology; Genetics; Glutamate receptor","score_opus":0.04743990798451598,"score_gpt":0.3136720887402553,"score_spread":0.26623218075573934,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168448982","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005535588,0.99389553,0.0025743912,0.0001921887,0.001143481,0.0018915622,0.00015243913,0.000023638533,0.00007142137],"genre_scores_gemma":[0.0013522479,0.9943788,0.00043535515,0.00091474544,0.0008640811,0.00068319583,0.0008551135,0.00017374664,0.00034270337],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.995723,0.00055297493,0.0013959741,0.0010641861,0.000578683,0.0006851642],"domain_scores_gemma":[0.9974675,0.00018366028,0.00096535275,0.0011977692,0.00009472123,0.0000909867],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008239716,0.0009446381,0.0016215974,0.00019903733,0.0001439689,0.00009857694,0.0011230846,0.0007611799,0.00032213744],"category_scores_gemma":[0.00006856887,0.0006255846,0.0009221148,0.00028426474,0.00013672146,0.00001892351,0.00011796873,0.0004620203,0.000015941767],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001849447,0.00073064334,0.0000015153435,0.00077460404,0.0006026595,0.0000049173204,0.0007249811,0.0000059023882,0.59699595,0.00070322555,0.0015073512,0.3977633],"study_design_scores_gemma":[0.00089984154,0.00058060116,0.0000013058232,0.0015602327,0.000030065174,0.000013467675,0.00020143816,0.000041526662,0.0339172,0.00007442408,0.96194184,0.00073807425],"about_ca_topic_score_codex":0.000030713687,"about_ca_topic_score_gemma":0.0000047320664,"teacher_disagreement_score":0.9604345,"about_ca_system_score_codex":0.000057493162,"about_ca_system_score_gemma":0.00018587845,"threshold_uncertainty_score":0.99961954},"labels":[],"label_agreement":null},{"id":"W2168549615","doi":"10.1111/j.1460-9568.2006.04748.x","title":"Evidence for a role of CaMKIV in the development of opioid analgesic tolerance","year":2006,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"U.S. Public Health Service","keywords":"CREB; Morphine; Opioid; Physical dependence; Knockout mouse; Receptor; Phosphorylation; Analgesic; Protein kinase A; Pharmacology; Transcription factor; Internal medicine; Endocrinology; Biology; Medicine; Cell biology; Gene; Biochemistry","score_opus":0.0357211056959843,"score_gpt":0.26825088369501293,"score_spread":0.23252977799902863,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168549615","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9843276,0.00094348466,0.014383038,0.000028078019,0.00010138522,0.00007238752,0.000001281449,5.2731764e-7,0.00014222614],"genre_scores_gemma":[0.99521446,0.00005397815,0.0045653647,0.00006602451,0.000072906805,8.108169e-7,3.2382454e-7,0.0000058943474,0.00002023604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901974,0.000131735,0.00042909462,0.00011712253,0.00019033768,0.000111946996],"domain_scores_gemma":[0.99939764,0.000029362303,0.000336071,0.000116025185,0.00010026743,0.000020624471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011958549,0.00006270388,0.000103714665,0.000045408367,0.000040075203,0.0000120295945,0.0004557831,0.000009802583,0.0000014835877],"category_scores_gemma":[0.00015588329,0.000043572032,0.00006306551,0.00013059069,0.000057272744,0.0000088903025,0.00003511104,0.000053258595,1.6429942e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004384725,0.00003443288,0.0004699304,0.000010571598,8.042613e-7,0.0000032504274,0.00018503895,0.00062379224,0.9960197,0.000037737555,0.00002841923,0.0025424603],"study_design_scores_gemma":[0.0002529094,0.0005015325,0.049670707,0.00012041301,0.000004324082,0.000027325706,0.00011921548,0.00015082498,0.9450414,0.000054576518,0.003993683,0.00006305165],"about_ca_topic_score_codex":0.0000013385986,"about_ca_topic_score_gemma":0.000002843056,"teacher_disagreement_score":0.050978277,"about_ca_system_score_codex":0.0000039132906,"about_ca_system_score_gemma":0.00009175782,"threshold_uncertainty_score":0.1776816},"labels":[],"label_agreement":null},{"id":"W2168587099","doi":"10.1016/s0960-894x(02)00608-x","title":"Novel substituted 4-aminomethylpiperidines as potent and selective human β3-agonists. Part 2: Arylethanolaminomethylpiperidines","year":2002,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Pharmacophore; Chemistry; Agonist; In vivo; Chemical synthesis; Structure–activity relationship; Stereochemistry; Pharmacology; Biological activity; Combinatorial chemistry; In vitro; Receptor; Biochemistry","score_opus":0.017267014079157896,"score_gpt":0.22308789373610444,"score_spread":0.20582087965694654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168587099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99353945,0.0026212046,0.0008384779,0.0018190695,0.0002897076,0.00021107942,0.000022272472,0.00005736316,0.00060138555],"genre_scores_gemma":[0.99599564,0.0004075113,0.0003756591,0.0009517809,0.0013947749,0.000037569367,0.0001717841,0.00006515745,0.0006001506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977459,0.000035321227,0.0004256826,0.00087114197,0.00035925306,0.0005627186],"domain_scores_gemma":[0.9989543,0.000023202385,0.00018519153,0.00043266718,0.00010224812,0.00030241092],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024328176,0.00047657592,0.0004039859,0.000060381637,0.00030348674,0.00006417996,0.0003362801,0.00027423585,0.00075424876],"category_scores_gemma":[0.00017326031,0.0004493528,0.00013628621,0.00025121967,0.0003237566,0.0000141037435,0.00013928462,0.00028382285,0.000018651555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032739463,0.0001008067,0.00028968664,0.00006946521,0.00012465012,0.000026806956,0.00014746541,0.0000024888752,0.9968505,0.000013819825,0.0016882042,0.0006534022],"study_design_scores_gemma":[0.0010405815,0.00012397727,0.00052931684,0.000054088854,0.0000788943,0.00036866718,0.00023328327,0.00002737545,0.98886853,0.00001084813,0.0081328275,0.00053160166],"about_ca_topic_score_codex":0.000048035334,"about_ca_topic_score_gemma":0.0000028387512,"teacher_disagreement_score":0.007981926,"about_ca_system_score_codex":0.00006047605,"about_ca_system_score_gemma":0.000041162013,"threshold_uncertainty_score":0.9997958},"labels":[],"label_agreement":null},{"id":"W2168831067","doi":"10.1091/mbc.e06-06-0567","title":"Endogenous ARF6 Interacts with Rac1 upon Angiotensin II Stimulation to Regulate Membrane Ruffling and Cell Migration","year":2006,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Membrane ruffling; Biology; RAC1; Cell biology; Endogeny; Stimulation; Angiotensin II; Cell migration; Rac GTP-Binding Proteins; Cell membrane; Cell; Signal transduction; Cytoskeleton; Neuroscience; Receptor; Biochemistry","score_opus":0.005500479251623355,"score_gpt":0.197793600763154,"score_spread":0.19229312151153063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168831067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9831056,0.00071852433,0.015300774,0.00021408864,0.00010093732,0.00028482408,0.0000071471873,0.000007962196,0.0002601481],"genre_scores_gemma":[0.9938335,0.000019231971,0.005510603,0.00017171176,0.00006275181,0.000005586664,0.00009426858,0.000022726304,0.00027964395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990796,0.000100942925,0.00021305213,0.0003239852,0.000078746256,0.00020365878],"domain_scores_gemma":[0.99941605,0.000010534989,0.00014925122,0.00029314996,0.000087479784,0.000043522494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015214193,0.00016773463,0.0001683574,0.00005165882,0.0001167485,0.000012320151,0.00014025456,0.00015997399,0.00000795789],"category_scores_gemma":[0.000014296032,0.00012253168,0.000078484234,0.000087130706,0.00004881313,0.0000033242354,0.0001260257,0.00007111521,0.0000014053013],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000113018286,0.0000451574,0.00026853153,0.000013013158,0.000015768906,0.0000023638918,0.000060328788,0.009114308,0.9900934,0.000050678962,0.000030891417,0.00019251253],"study_design_scores_gemma":[0.0004679291,0.0005109206,0.00022783893,0.000019986846,0.00003608557,0.000016924369,0.0000145881,0.00045386018,0.9968662,0.00016838322,0.0010615108,0.00015575039],"about_ca_topic_score_codex":0.00012285386,"about_ca_topic_score_gemma":0.00005180126,"teacher_disagreement_score":0.010727882,"about_ca_system_score_codex":0.000009659617,"about_ca_system_score_gemma":0.000024534289,"threshold_uncertainty_score":0.49966967},"labels":[],"label_agreement":null},{"id":"W2169609258","doi":"10.1139/cjpp-2013-0091","title":"Celiprolol induces β<sub>3</sub>-adrenoceptors-dependent relaxation in isolated porcine coronary arteries","year":2013,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Celiprolol; Vasodilation; Antagonist; Chemistry; Endothelium; Nadolol; Nitric oxide; Internal medicine; Vasoconstriction; Endocrinology; Receptor; Pharmacology; Medicine; Biochemistry; Heart rate; Blood pressure","score_opus":0.007245301103169214,"score_gpt":0.21789766010776654,"score_spread":0.21065235900459733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169609258","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99752575,0.0010784719,0.0000616286,0.00037353777,0.0007762345,0.00014542777,0.0000067716337,0.0000021050146,0.000030094274],"genre_scores_gemma":[0.9984643,0.0003895217,0.000048163263,0.0007403806,0.0002786562,0.000011579964,0.000027588543,0.000013130612,0.000026703137],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899924,0.0001558233,0.00032417892,0.00018832428,0.00004098512,0.00029143158],"domain_scores_gemma":[0.9993285,0.000019284498,0.00021201282,0.000065091386,0.00012829465,0.00024680985],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017494806,0.00014108454,0.00023008279,0.0001597811,0.000092474824,0.000011283669,0.00012778162,0.00024884014,0.0012280504],"category_scores_gemma":[0.00001739551,0.00012935264,0.000047944286,0.0000646955,0.00012822126,0.000020133415,0.00002142747,0.00026512155,0.000010213721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105574814,0.00001813473,0.0015931102,0.00001270321,0.000057296114,0.00002429311,0.00014383544,0.00013208674,0.99520653,0.000015550504,0.0012565865,0.0014343181],"study_design_scores_gemma":[0.00085485936,0.00079901307,0.011535258,0.000010145996,0.000022013623,0.00016303481,0.00010959694,0.00006581185,0.9847994,0.0007370964,0.00076351577,0.0001402672],"about_ca_topic_score_codex":0.0002702418,"about_ca_topic_score_gemma":0.0006774837,"teacher_disagreement_score":0.010407124,"about_ca_system_score_codex":0.000021644091,"about_ca_system_score_gemma":0.0002809997,"threshold_uncertainty_score":0.999685},"labels":[],"label_agreement":null},{"id":"W2169673925","doi":"10.2174/1568026611313010004","title":"The Therapeutic Potential of Allosteric Ligands for Free Fatty Acid Sensitive GPCRs","year":2013,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Wellcome Trust; Canadian Institutes of Health Research; Strategiske Forskningsråd","keywords":"Allosteric regulation; G protein-coupled receptor; Chemistry; Fatty acid; Computational biology; Biochemistry; Combinatorial chemistry; Biology; Receptor","score_opus":0.03752317418301737,"score_gpt":0.3281426430285333,"score_spread":0.2906194688455159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169673925","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001003302,0.9951212,0.0022422376,0.00003496258,0.0008981957,0.0005546237,0.000052275605,0.0000049582327,0.000088262816],"genre_scores_gemma":[0.0010755883,0.9965266,0.00014162871,0.000016169992,0.001492789,0.00016176792,0.0003461473,0.000035395646,0.00020388592],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99840915,0.000036084206,0.00060166704,0.00040592684,0.00022963612,0.0003175212],"domain_scores_gemma":[0.998839,0.000051433835,0.00036178768,0.0005390146,0.0001319516,0.00007677701],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033999034,0.0003441976,0.0007143948,0.000023835888,0.000076696124,0.000022920942,0.0005703139,0.00039520205,0.000024358855],"category_scores_gemma":[0.00015043326,0.00023048026,0.0004002079,0.000079788915,0.00013926958,0.0000023260247,0.00018601892,0.00037866563,0.0000011809806],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002325797,0.000044441338,0.0000017947146,0.006846168,0.00014581902,0.0000022674071,0.000024376917,7.567532e-7,0.06692101,0.000035875466,0.0005864104,0.92536783],"study_design_scores_gemma":[0.0004984167,0.00012394007,0.0000010846077,0.0030856053,0.00032062686,0.000032225897,0.000103446044,0.000024416187,0.19503595,0.0002807973,0.8001604,0.00033309884],"about_ca_topic_score_codex":0.0000019299482,"about_ca_topic_score_gemma":9.661259e-7,"teacher_disagreement_score":0.9250347,"about_ca_system_score_codex":0.000038106027,"about_ca_system_score_gemma":0.00020872519,"threshold_uncertainty_score":0.9398712},"labels":[],"label_agreement":null},{"id":"W2170363216","doi":"10.1016/s1499-2671(11)52131-8","title":"Characterisation of angiotensin II type II receptor implication during adipogenesis","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Adipogenesis; Adipocyte; Endocrinology; Internal medicine; Angiotensin II; Receptor; Adipose tissue; Agonist; Renin–angiotensin system; Medicine","score_opus":0.013197196254507406,"score_gpt":0.19567635431541808,"score_spread":0.18247915806091067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170363216","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987367,0.0007965736,0.000021138489,0.000053661235,0.00026347194,0.00004494761,0.000012573913,0.0000013017525,0.00006968039],"genre_scores_gemma":[0.9987583,0.000028722761,0.0008668349,0.00004041573,0.00020131508,9.2082087e-7,0.000019458217,0.000013517758,0.00007051408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99942726,0.000023347702,0.00024196503,0.00009052315,0.00005574984,0.00016118187],"domain_scores_gemma":[0.99919075,0.0000024223727,0.00023249422,0.0001198886,0.00027476563,0.00017967401],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001462753,0.00007612836,0.00012778009,0.00010493663,0.00011241882,0.000006404227,0.00011902667,0.00008945207,0.00029610994],"category_scores_gemma":[0.000050864048,0.000073755706,0.00007870024,0.00007740192,0.000027626711,0.000009046953,0.000014643623,0.00004487076,0.0000018379188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000070418464,0.000008911408,0.010844606,0.0000067016126,0.000049114275,3.0430374e-7,0.0002718007,0.0000024342319,0.9869249,0.000018879326,0.00022115184,0.0016441917],"study_design_scores_gemma":[0.0001323383,0.00039859925,0.051068496,0.000029733079,0.000021330352,0.0000024682415,0.000042968226,0.0000024784958,0.946192,0.000035277015,0.001994257,0.00008002237],"about_ca_topic_score_codex":0.00010666363,"about_ca_topic_score_gemma":0.00014544337,"teacher_disagreement_score":0.04073283,"about_ca_system_score_codex":0.000021075724,"about_ca_system_score_gemma":0.00020880387,"threshold_uncertainty_score":0.3242196},"labels":[],"label_agreement":null},{"id":"W2170880851","doi":"10.1002/jcp.23058","title":"Gender related alterations of β‐adrenoceptor mechanisms in heart failure due to arteriovenous fistula","year":2011,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Heart failure; Arteriovenous fistula; Internal medicine; Cardiology; Medicine; Surgery","score_opus":0.012889379533335922,"score_gpt":0.21653662330838114,"score_spread":0.20364724377504523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170880851","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97328854,0.00021592982,0.02586452,0.00006930168,0.0003326721,0.00011725444,0.000006019752,0.0000025180843,0.000103251514],"genre_scores_gemma":[0.985253,0.000014255515,0.014372115,0.00015110534,0.00012480325,0.000003642995,0.00001658105,0.000019616687,0.000044900647],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99879616,0.00013797729,0.0005574336,0.00018669032,0.00011164578,0.0002101054],"domain_scores_gemma":[0.9992623,0.000009457592,0.00027021876,0.00020283707,0.00015890706,0.000096324664],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002832775,0.00013786103,0.0003643236,0.00013102779,0.00003382076,0.0000053976523,0.00019747298,0.00018305826,0.0005170755],"category_scores_gemma":[0.000035410194,0.00012266896,0.00017631977,0.000108719076,0.00003145924,0.000007637415,0.000055850676,0.00015701192,0.000009173581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010709921,0.00013645878,0.00002408237,0.00001189083,0.00006208688,0.000014710981,0.00045306043,0.00020195027,0.9978561,0.00068665243,0.00037313084,0.000072797964],"study_design_scores_gemma":[0.00046799678,0.0011728226,0.000851257,0.000021122243,0.000018046301,0.0001054592,0.00019238709,0.000026501823,0.9913946,0.004464209,0.0011564008,0.00012919852],"about_ca_topic_score_codex":0.000010907184,"about_ca_topic_score_gemma":0.000008019445,"teacher_disagreement_score":0.011964447,"about_ca_system_score_codex":0.000013464607,"about_ca_system_score_gemma":0.00008451152,"threshold_uncertainty_score":0.5661614},"labels":[],"label_agreement":null},{"id":"W2171149904","doi":"10.1002/jlcr.1917","title":"[<sup>11</sup>C]Methyl‐losartan as a potential ligand for PET imaging angiotensin II AT<sub>1</sub> receptors","year":2011,"lang":"en","type":"article","venue":"Journal of Labelled Compounds and Radiopharmaceuticals","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Losartan; Chemistry; Tetrazole; Radioligand; Angiotensin II; Angiotensin II receptor type 1; Angiotensin receptor; Receptor; Renin–angiotensin system; Ligand (biochemistry); Pharmacology; Blood pressure; Internal medicine; Stereochemistry; Biochemistry; Medicine","score_opus":0.017777778221410665,"score_gpt":0.2686178055258964,"score_spread":0.25084002730448574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171149904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99039555,0.0063484306,0.0016645588,0.00052709354,0.0006191565,0.00028206655,0.000016285123,0.000011934757,0.0001349305],"genre_scores_gemma":[0.9907476,0.002205661,0.005342956,0.0006043705,0.0008337631,0.0000071862146,0.000016694996,0.000058001177,0.00018381228],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99794257,0.00014016793,0.0007281986,0.00038655841,0.00029413108,0.0005083581],"domain_scores_gemma":[0.9985702,0.000054432763,0.00038138466,0.0002051426,0.0003517771,0.00043708572],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00093060156,0.0003345706,0.00054866995,0.00014827565,0.00048083637,0.00006794298,0.0002612821,0.00015051577,0.000064820175],"category_scores_gemma":[0.000092760856,0.00028082082,0.00039657837,0.00011491159,0.00016338567,0.000025179093,0.00019030836,0.0002446078,0.0000038571766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015794174,0.00033108954,0.00019888696,0.000028780165,0.00029707697,0.000095231146,0.00027196947,0.000031225492,0.9912073,0.00012833848,0.00367252,0.002158141],"study_design_scores_gemma":[0.0059801093,0.0013059766,0.000026257416,0.00006583146,0.0002977838,0.0015080724,0.00017235022,0.0019359378,0.95389515,0.0006962958,0.033733286,0.00038294756],"about_ca_topic_score_codex":0.000004588497,"about_ca_topic_score_gemma":0.000001099531,"teacher_disagreement_score":0.037312172,"about_ca_system_score_codex":0.000040482635,"about_ca_system_score_gemma":0.0001048746,"threshold_uncertainty_score":0.9999644},"labels":[],"label_agreement":null},{"id":"W2171194536","doi":"10.1002/iub.293","title":"Agonist‐selective signaling of G protein‐coupled receptor: Mechanisms and implications","year":2010,"lang":"en","type":"review","venue":"IUBMB Life","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Tellabs (Canada)","funders":"National Institute on Drug Abuse; National Institutes of Health","keywords":"G protein-coupled receptor; Agonist; Functional selectivity; Signal transduction; G protein; Arrestin; Receptor; Cell biology; Biology; Chemistry; Neuroscience; Biochemistry","score_opus":0.02270325257743989,"score_gpt":0.29080117918443055,"score_spread":0.26809792660699067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171194536","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000575528,0.9885829,0.008947745,0.0000240397,0.00021866041,0.0012526928,0.00014123796,0.000024513069,0.00023266797],"genre_scores_gemma":[0.0016743203,0.9864754,0.009978538,0.000047368107,0.000462458,0.00045147783,0.0004915083,0.00011219947,0.00030669812],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980777,0.00012286549,0.00064924645,0.0006656228,0.00016526278,0.0003193239],"domain_scores_gemma":[0.99846697,0.000037986178,0.00058071554,0.00052376307,0.00018978649,0.00020077462],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003835328,0.00043145288,0.0010022765,0.000105409905,0.00015021491,0.000045271016,0.0003413082,0.00081156555,0.00010440769],"category_scores_gemma":[0.00021320583,0.00038150515,0.00036894373,0.00017614441,0.000085601336,0.000004509754,0.0001605262,0.00040586543,0.000012400317],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017897411,0.00006292539,7.2644576e-7,0.0020837074,0.00027512602,4.9829805e-7,0.000028076236,0.000001280444,0.7774752,0.003958362,0.00016681108,0.21592943],"study_design_scores_gemma":[0.00023129728,0.0002939034,4.715889e-7,0.0012833236,0.0003347398,0.000019335017,0.000025938736,0.0000056299227,0.09307905,0.0009934774,0.903141,0.0005918182],"about_ca_topic_score_codex":0.000017655597,"about_ca_topic_score_gemma":0.00000603104,"teacher_disagreement_score":0.9029742,"about_ca_system_score_codex":0.000020020603,"about_ca_system_score_gemma":0.0005355323,"threshold_uncertainty_score":0.9998637},"labels":[],"label_agreement":null},{"id":"W2171965271","doi":"10.1152/ajpheart.00657.2011","title":"Nuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signaling","year":2011,"lang":"en","type":"review","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Montreal Heart Institute","funders":"Canadian Institutes of Health Research","keywords":"Signal transduction; G protein-coupled receptor; Receptor; Biology; Cell biology; Phenotype; Repertoire; Neuroscience; Nucleus; Computational biology; Genetics; Gene; Physics","score_opus":0.023510213586707993,"score_gpt":0.26905694144442033,"score_spread":0.24554672785771234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171965271","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42207298,0.5774542,0.0000020600369,0.000002261853,0.00027211226,0.00016284622,0.000013501632,0.0000054570783,0.000014544224],"genre_scores_gemma":[0.28880885,0.70986706,0.00045221992,0.0001261802,0.00058913266,0.000010758794,0.000055849876,0.00008650277,0.0000034704663],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99618924,0.0010841208,0.001345643,0.0007503927,0.0001441643,0.0004864193],"domain_scores_gemma":[0.9973153,0.00007007063,0.0015963372,0.00058797403,0.00020000087,0.00023032758],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00059826026,0.0005894699,0.0033096399,0.00033916268,0.00007802216,0.000010116142,0.00050886994,0.00048796553,0.00014552036],"category_scores_gemma":[0.00004436768,0.00049456715,0.00087397394,0.0002938299,0.00071792904,0.000023008888,0.0001647286,0.00061222806,0.0000066543885],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009358459,0.00011683115,0.000010441513,0.00086516637,0.0004119864,6.721563e-7,0.00012439693,0.000043682965,0.9593386,0.00010358236,0.00004516138,0.038845915],"study_design_scores_gemma":[0.0014735364,0.009013886,0.002890641,0.0054156613,0.0011451709,0.00060810556,0.001135086,0.00001471736,0.010505137,0.00092305517,0.96480244,0.0020725392],"about_ca_topic_score_codex":0.0000459821,"about_ca_topic_score_gemma":0.000002524534,"teacher_disagreement_score":0.9647573,"about_ca_system_score_codex":0.000038442402,"about_ca_system_score_gemma":0.00036333158,"threshold_uncertainty_score":0.9997506},"labels":[],"label_agreement":null},{"id":"W2174452576","doi":"10.1152/ajpendo.2001.280.1.e193","title":"Increased density of glucagon receptors in liver from endurance-trained rats","year":2001,"lang":"en","type":"article","venue":"American Journal of Physiology-Endocrinology and Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; Université de Montréal; Université du Québec à Trois-Rivières","funders":"","keywords":"Glucagon; Internal medicine; Endocrinology; Receptor; Chemistry; Incubation; Glucagon receptor; Medicine; Biochemistry; Hormone","score_opus":0.007461180389380601,"score_gpt":0.22649301562344104,"score_spread":0.21903183523406045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2174452576","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995661,0.0034833201,0.0002605135,0.00007860028,0.0003911558,0.00006978465,0.000008693183,0.00000377879,0.00004313965],"genre_scores_gemma":[0.98990643,0.007682686,0.0017473494,0.00026867032,0.00034704412,0.000003099342,0.0000139588265,0.000013605897,0.000017167986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847275,0.00037030643,0.00047587097,0.00027515966,0.000089827605,0.00031609123],"domain_scores_gemma":[0.998978,0.000067219844,0.00052351854,0.000189084,0.00013857601,0.00010360619],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019262054,0.00019014408,0.0006689242,0.00014218067,0.000046811405,0.0000040152527,0.00020698908,0.000105915824,0.00009860964],"category_scores_gemma":[0.0001102807,0.0001616997,0.000145972,0.00014933731,0.00045130047,0.000012993892,0.000075208125,0.00027044534,0.0000015254495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008599342,0.00008588363,0.004395815,0.000003926234,0.00014170165,0.000019780367,0.00015448633,0.000017471002,0.97195613,0.00016563828,0.000055118417,0.022144105],"study_design_scores_gemma":[0.0015382464,0.00056947744,0.24207142,0.000023641514,0.000075654025,0.00016385486,0.0006146614,0.000012850624,0.74806046,0.000832512,0.0058352477,0.00020198314],"about_ca_topic_score_codex":0.00041955427,"about_ca_topic_score_gemma":0.00004162004,"teacher_disagreement_score":0.23767559,"about_ca_system_score_codex":0.000007653051,"about_ca_system_score_gemma":0.00007264785,"threshold_uncertainty_score":0.6593923},"labels":[],"label_agreement":null},{"id":"W2174855058","doi":"10.1016/s0960-894x(03)00387-1","title":"Cyclic amine sulfonamides as linkers in the design and synthesis of novel human β3 adrenergic receptor agonists","year":2003,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Azetidine; Piperidine; Chemistry; Pyrrolidine; Agonist; Adrenergic receptor; Selectivity; Stereochemistry; Amine gas treating; BETA (programming language); Chemical synthesis; Receptor; Biochemistry; In vitro; Organic chemistry","score_opus":0.014690528677062484,"score_gpt":0.23889076455244215,"score_spread":0.22420023587537968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2174855058","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996317,0.0006546427,0.0015764594,0.0009056055,0.00007093752,0.00016654497,0.0000064144247,0.000008849634,0.00029352342],"genre_scores_gemma":[0.99756366,0.00016774135,0.0011675459,0.0007452276,0.00018595502,0.000026348083,0.00003672109,0.000027083383,0.00007969982],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985165,0.000111331065,0.0003690292,0.00042041056,0.00027368238,0.00030905148],"domain_scores_gemma":[0.99926287,0.000094895724,0.00016384253,0.00034395463,0.000039413157,0.000094999974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070854573,0.00025466076,0.00027571907,0.000034365006,0.00009430151,0.000020709094,0.00030538795,0.00019088482,0.00014689917],"category_scores_gemma":[0.00041261976,0.00019911063,0.00007789962,0.00016118234,0.00022625538,0.0000048350375,0.000038065537,0.00017881778,0.0000018680106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003806782,0.00009301883,0.0001893145,0.00006210745,0.000043775333,0.000008046649,0.00011389085,0.000019188266,0.998763,0.000056223125,0.00046206656,0.00015125578],"study_design_scores_gemma":[0.00075645326,0.00008760133,0.00015641759,0.000087062646,0.000043220203,0.0000865513,0.00048238455,0.000010403349,0.9960507,0.000020775176,0.0019999875,0.00021840817],"about_ca_topic_score_codex":0.000042417323,"about_ca_topic_score_gemma":0.0000023842297,"teacher_disagreement_score":0.00271231,"about_ca_system_score_codex":0.000029419385,"about_ca_system_score_gemma":0.00007012245,"threshold_uncertainty_score":0.8119496},"labels":[],"label_agreement":null},{"id":"W2175419213","doi":"10.1073/pnas.1521260112","title":"Altered <i>Escherichia coli</i> membrane protein assembly machinery allows proper membrane assembly of eukaryotic protein vitamin K epoxide reductase","year":2015,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; Government of Canada; National Institutes of Health; Canadian Institutes of Health Research; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; U.S. Public Health Service","keywords":"Vitamin K epoxide reductase; Escherichia coli; Membrane protein; Biology; Biochemistry; Reductase; VKORC1; Mutant; Vesicle-associated membrane protein 8; Enzyme; Cell biology; Membrane; Gene","score_opus":0.03200534657750815,"score_gpt":0.27398960001642403,"score_spread":0.2419842534389159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2175419213","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99609184,0.0001944675,0.000013645509,0.000906218,0.000036779995,0.00077619887,0.000022830778,0.000008706014,0.0019492912],"genre_scores_gemma":[0.99097425,0.000012959821,0.007970609,0.00015214834,0.00016045707,0.00006441254,0.0000021861897,0.000015678157,0.00064729975],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974501,0.0000385958,0.0005862499,0.0004316086,0.0012357342,0.00025768872],"domain_scores_gemma":[0.9985612,0.000016875412,0.0007021846,0.000031505155,0.0005846032,0.000103627404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023410975,0.0002018369,0.0003016888,0.0001123115,0.00011201695,0.000030250465,0.0009224234,0.00018215725,0.00001123789],"category_scores_gemma":[0.0007835931,0.0001384093,0.00013740097,0.00050608086,0.0004491531,0.000064121734,0.00022003618,0.0001865184,0.0000011604225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000110963214,0.0001095257,0.00010068154,0.00015999348,0.000037354406,2.4907798e-8,0.000071863185,0.00019537195,0.9964106,0.0024078065,0.00032131156,0.00007447114],"study_design_scores_gemma":[0.00045747185,0.0002948581,0.00025484702,0.00017610475,0.000019308343,0.000007976961,0.00015325939,0.0006620212,0.9961791,0.0013905014,0.00023605797,0.00016850991],"about_ca_topic_score_codex":0.000024416786,"about_ca_topic_score_gemma":2.7666727e-7,"teacher_disagreement_score":0.007956964,"about_ca_system_score_codex":0.000024126677,"about_ca_system_score_gemma":0.00019784884,"threshold_uncertainty_score":0.56441677},"labels":[],"label_agreement":null},{"id":"W2176195848","doi":"10.1016/s0960-894x(02)00303-7","title":"Novel human metabolites of the angiotensin-II antagonist tasosartan and their pharmacological effects","year":2002,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Metabolite; Chemistry; In vivo; Antagonist; Pharmacology; Angiotensin II; Active metabolite; Renin–angiotensin system; Receptor antagonist; Receptor; Endocrinology; Biochemistry; Blood pressure; Medicine; Biology","score_opus":0.011202885527761169,"score_gpt":0.2173492214301445,"score_spread":0.20614633590238335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2176195848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99493796,0.002323258,0.0002884503,0.0020218152,0.00016123838,0.00013752743,0.00001730376,0.000013089235,0.000099360375],"genre_scores_gemma":[0.9975522,0.0000897202,0.00018751688,0.0014875851,0.0005236049,0.0000054435154,0.00002131303,0.000021237605,0.00011136978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989426,0.000035489375,0.00023460435,0.00035193362,0.00016727846,0.00026810335],"domain_scores_gemma":[0.999431,0.000023333838,0.00013388267,0.0002627311,0.000039816936,0.00010924276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015106863,0.00023331381,0.00025434032,0.000012565447,0.00022470769,0.000013549578,0.00027233554,0.00014376009,0.00021933093],"category_scores_gemma":[0.000067608846,0.00014810589,0.00012497202,0.000103349754,0.00031298358,0.0000034083623,0.00017747718,0.0001703167,9.16712e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011675647,0.00006799887,0.00022037525,0.00004159082,0.00009693793,0.0000030026988,0.00008851705,5.401312e-7,0.99701583,0.000009333064,0.0021689523,0.0002752692],"study_design_scores_gemma":[0.00071462744,0.00007296415,0.0004606994,0.000035110006,0.00008209423,0.00008920001,0.000059970454,0.000024875064,0.9943326,0.000007745287,0.0039487765,0.00017132297],"about_ca_topic_score_codex":0.00000883969,"about_ca_topic_score_gemma":5.4596666e-7,"teacher_disagreement_score":0.0026831925,"about_ca_system_score_codex":0.0000131143925,"about_ca_system_score_gemma":0.000012976762,"threshold_uncertainty_score":0.6039583},"labels":[],"label_agreement":null},{"id":"W2181877822","doi":"10.1371/journal.pbio.1002305","title":"Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα","year":2015,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Protein subunit; Biology; Binding site; Second messenger system; Degeneracy (biology); Conformational change; Plasma protein binding; Biochemistry; Biophysics; Stereochemistry; Enzyme; Chemistry; Genetics; Gene","score_opus":0.041096127317885596,"score_gpt":0.24149537433944993,"score_spread":0.20039924702156434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2181877822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7821391,0.00018267312,0.21701828,0.0002173893,0.00005164153,0.00016670904,0.000028028846,0.000004582502,0.00019155706],"genre_scores_gemma":[0.99841285,0.000053790387,0.0010486552,0.00007767399,0.00014506413,0.00005378132,0.00015266183,0.0000068605455,0.000048657337],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999458,0.000033124226,0.00020244693,0.00012556219,0.00006801514,0.0001128299],"domain_scores_gemma":[0.9994709,0.000052752606,0.00017533901,0.00011577389,0.00016195903,0.00002330211],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002777076,0.000080321865,0.000113299895,0.000040292925,0.00010411178,0.000008199707,0.00009229209,0.00013182865,0.00000797433],"category_scores_gemma":[0.00005921337,0.000049984905,0.00004422572,0.00006781257,0.000058974256,0.0000081864155,0.000058088914,0.000045171622,1.433502e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014250645,0.000019331424,0.00040197273,0.000014243161,0.00007646384,1.3951942e-8,0.00037141595,0.0010494475,0.98739415,0.009905226,0.00028060196,0.00034459424],"study_design_scores_gemma":[0.0014051243,0.00023489675,0.00005288587,0.000018889701,0.000022430446,0.00000678402,0.00059773953,0.069030926,0.9222072,0.0053420174,0.0009898387,0.00009131085],"about_ca_topic_score_codex":0.00001951115,"about_ca_topic_score_gemma":0.000026268566,"teacher_disagreement_score":0.21627371,"about_ca_system_score_codex":0.00000953466,"about_ca_system_score_gemma":0.0000649525,"threshold_uncertainty_score":0.20383252},"labels":[],"label_agreement":null},{"id":"W2181925771","doi":"10.1016/j.healun.2015.10.021","title":"Sex-related differences in age-associated downregulation of human ventricular myocardial β1-adrenergic receptors","year":2015,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"National Heart, Lung, and Blood Institute; U.S. Public Health Service; National Institutes of Health","keywords":"Downregulation and upregulation; Adrenergic receptor; Receptor; Internal medicine; Adrenergic; Cardiology; β2 adrenergic receptor; Medicine; Endocrinology; Biology; Agonist; Gene","score_opus":0.013611491046863131,"score_gpt":0.24180680042237496,"score_spread":0.22819530937551183,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2181925771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986788,0.0007982159,0.00027799688,0.00004063221,0.00010916912,0.000063725885,0.0000021451062,0.0000015865301,0.000027722903],"genre_scores_gemma":[0.9994707,0.00035332912,0.000048367867,0.000009664493,0.000048995676,5.923245e-7,0.000038663213,0.0000049275905,0.00002473533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923855,0.00019923151,0.00028043994,0.000056684203,0.0001476823,0.0000773989],"domain_scores_gemma":[0.9996925,0.000017001408,0.00014998404,0.000042326206,0.000061895895,0.00003626794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007171025,0.000064874584,0.00015234842,0.00005633656,0.000039710092,0.000008269723,0.00005202026,0.00008011492,0.0000067280407],"category_scores_gemma":[0.000011796604,0.000044942193,0.00004967654,0.000073154544,0.000028784922,0.000008436669,0.0000043487003,0.0000750804,1.2294782e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019472987,0.000037525046,0.014155535,0.000015579757,0.00007611593,0.000005595211,0.001772106,0.0011160041,0.98237115,0.000039059098,0.00006965653,0.00014693683],"study_design_scores_gemma":[0.005177374,0.0018666482,0.2038248,0.00030351177,0.00043467464,0.00023427428,0.001573997,0.0009184412,0.78389144,0.0013910045,0.0000855928,0.00029823554],"about_ca_topic_score_codex":0.00004058243,"about_ca_topic_score_gemma":0.00001717221,"teacher_disagreement_score":0.19847971,"about_ca_system_score_codex":0.000010004971,"about_ca_system_score_gemma":0.000025728972,"threshold_uncertainty_score":0.18326893},"labels":[],"label_agreement":null},{"id":"W2182302719","doi":"10.1016/s0026-895x(24)05619-0","title":"Agonist-Induced Internalization of Leukotriene B4 Receptor 1 Requires G-Protein-Coupled Receptor Kinase 2 but Not Arrestins","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Internalization; Beta adrenergic receptor kinase; G protein-coupled receptor; G protein-coupled receptor kinase; Cell biology; Receptor; HEK 293 cells; Leukotriene B4; Biology; Agonist; Leukotriene receptor; Chemistry; Signal transduction; Biochemistry; Inflammation; Immunology; Antagonist","score_opus":0.014698202094454738,"score_gpt":0.27337789392726364,"score_spread":0.2586796918328089,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2182302719","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93147975,0.00039011493,0.06593278,0.00033732696,0.00093305105,0.00072341226,0.00003724244,0.000041718955,0.00012460405],"genre_scores_gemma":[0.99401224,0.0001117308,0.003891837,0.000830561,0.00041521539,0.00017912213,0.00027355104,0.000078195444,0.00020754291],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977756,0.00019423636,0.0005940939,0.00066346844,0.000280483,0.0004920772],"domain_scores_gemma":[0.99878794,0.000013699521,0.000355378,0.00037897375,0.00026691196,0.00019709488],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031870895,0.00035158737,0.00038298272,0.00013485082,0.000119358694,0.000027308035,0.00044612464,0.00034731024,0.0007818738],"category_scores_gemma":[0.00014817805,0.00037030678,0.0002330155,0.00021502105,0.00013198881,0.000012397903,0.00020266094,0.00021592423,0.000044850814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005287187,0.00019262976,0.000015020055,0.000048154572,0.00015796331,0.000027780588,0.0000610681,0.001097319,0.99580175,0.0009458545,0.0002913276,0.0008323891],"study_design_scores_gemma":[0.0024402374,0.00088634476,0.00000942197,0.000056626734,0.00006002386,0.0000124190265,0.00003684842,0.00015255297,0.9896927,0.00024537736,0.0060335696,0.0003739163],"about_ca_topic_score_codex":0.00015079656,"about_ca_topic_score_gemma":0.000009104022,"teacher_disagreement_score":0.0625325,"about_ca_system_score_codex":0.00008859502,"about_ca_system_score_gemma":0.0002674209,"threshold_uncertainty_score":0.9998749},"labels":[],"label_agreement":null},{"id":"W2182941348","doi":"10.1124/mol.104.004549","title":"Reciprocal Regulation of Agonist and Inverse Agonist Signaling Efficacy upon Short-Term Treatment of the Human δ-Opioid Receptor with an Inverse Agonist","year":2004,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut universitaire en santé mentale de Montréal","funders":"","keywords":"Inverse agonist; Agonist; Chemistry; Partial agonist; Receptor; G protein; GTP'; Diprenorphine; μ-opioid receptor; Stereochemistry; Endocrinology; Pharmacology; Opioid receptor; Biochemistry; Biology","score_opus":0.015935248800061533,"score_gpt":0.2773263005057262,"score_spread":0.2613910517056647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2182941348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974119,0.00020685223,0.0013501941,0.00009828116,0.00020889867,0.0005984449,0.000024652078,0.000014697256,0.00008607739],"genre_scores_gemma":[0.9970319,0.00008786846,0.0022397167,0.00013885275,0.00014613241,0.000042128748,0.00020977415,0.000046182864,0.00005740756],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998376,0.00020532706,0.00040312685,0.000517882,0.00019657238,0.00030107773],"domain_scores_gemma":[0.9991142,0.0000113678525,0.00023800418,0.00036710073,0.00012902769,0.00014027677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016672115,0.00029784045,0.0003452342,0.000067562476,0.00024168308,0.000023430905,0.0002247175,0.00021906555,0.000091000315],"category_scores_gemma":[0.000010338831,0.00023259927,0.00015342522,0.00014010484,0.0003594478,0.000011478182,0.0000871139,0.00011003723,0.0000012505017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042250266,0.00041425464,0.00054984435,0.00004098837,0.00018353715,0.000011555815,0.0003087406,0.0027585973,0.99406403,0.00022878726,0.00002773537,0.0009894517],"study_design_scores_gemma":[0.002790199,0.0024841884,0.00052384596,0.000034003126,0.00021056802,0.000023845387,0.00009723484,0.00011325275,0.9922238,0.000104356994,0.0011461091,0.0002486037],"about_ca_topic_score_codex":0.000097484415,"about_ca_topic_score_gemma":0.00008792999,"teacher_disagreement_score":0.0026453445,"about_ca_system_score_codex":0.00007907767,"about_ca_system_score_gemma":0.00017418955,"threshold_uncertainty_score":0.94851226},"labels":[],"label_agreement":null},{"id":"W2185872884","doi":"10.26443/mjm.v8i1.516","title":"Mouse Models in Cardiology Research","year":2020,"lang":"en","type":"article","venue":"McGill Journal of Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"University of North Carolina at Chapel Hill","keywords":"Medicine; Internal medicine; Cardiology","score_opus":0.12521404370586126,"score_gpt":0.348413225989763,"score_spread":0.22319918228390173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2185872884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96862173,0.0035295365,0.008990672,0.014425945,0.00032739437,0.00014209366,0.0000070993256,0.0000041794024,0.0039513647],"genre_scores_gemma":[0.99608094,0.0009413432,0.0003997339,0.0016066416,0.0008911381,0.0000010768927,0.0000033156648,0.00001157052,0.00006425865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989384,0.00017657412,0.00031958602,0.0001275094,0.00025713062,0.00018081385],"domain_scores_gemma":[0.9994475,0.000022680195,0.00008288686,0.00009195323,0.00021269936,0.00014226897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011565144,0.00007000639,0.00025793622,0.000087318054,0.00003689682,0.000002109789,0.0001979558,0.000092763876,0.000048439404],"category_scores_gemma":[0.0003143651,0.0000508501,0.000052600786,0.00012113166,0.000062286534,0.0000036577105,0.000054729226,0.00028326688,0.0000022487557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017635981,0.000009453697,0.00007444738,0.000009281391,0.000027729904,0.00008124745,0.000087367465,0.0026858286,0.9848921,0.0003271313,0.00983995,0.00178913],"study_design_scores_gemma":[0.006255113,0.0074138134,0.00011213252,0.00016483296,0.000033758704,0.0003135526,0.0018163938,0.0017565314,0.71142,0.0035634,0.26686954,0.00028090805],"about_ca_topic_score_codex":0.000009689252,"about_ca_topic_score_gemma":0.0000018749131,"teacher_disagreement_score":0.27347207,"about_ca_system_score_codex":0.0000139571375,"about_ca_system_score_gemma":0.000029841887,"threshold_uncertainty_score":0.2073607},"labels":[],"label_agreement":null},{"id":"W2185980467","doi":"10.4172/2153-0645.1000120","title":"G-Protein Coupled Receptors Dimerization: Diversity in Somatostatin Receptors Subtypes","year":2013,"lang":"en","type":"article","venue":"Journal of Pharmacogenomics & Pharmacoproteomics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Michael Smith Health Research BC","keywords":"Receptor; Somatostatin receptor; Somatostatin; Diversity (politics); G protein-coupled receptor; Functional diversity; Biology; Neuroscience; Ecology; Genetics; Sociology; Anthropology","score_opus":0.01370828373761132,"score_gpt":0.25053039161067686,"score_spread":0.23682210787306554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2185980467","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992019,0.00071371475,0.004819058,0.00023663849,0.0013934997,0.0007233662,0.000010709804,0.00001175915,0.00007223868],"genre_scores_gemma":[0.9871187,0.0014727968,0.009819882,0.00043171915,0.00077181734,0.000027187498,0.000036778987,0.00006713116,0.0002539439],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977779,0.00018632133,0.00090696506,0.00034280965,0.00034059343,0.00044542656],"domain_scores_gemma":[0.9983272,0.000023235254,0.00077769306,0.00018513671,0.00039382654,0.00029290837],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000794125,0.0003321858,0.00041676778,0.00023182336,0.00020323876,0.00007750372,0.0006000654,0.0001812063,0.0012165535],"category_scores_gemma":[0.00007329965,0.00033140328,0.0002453002,0.00026014182,0.00007826893,0.00006449116,0.00033709023,0.00044013088,0.000044679633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003759912,0.00013552106,0.0036558332,0.000027400827,0.00014824435,0.00001145229,0.00027392333,0.0015474334,0.98943454,0.00002217277,0.0017100496,0.0026574614],"study_design_scores_gemma":[0.0028209102,0.0002488404,0.00013364092,0.000041424682,0.000058255016,0.000043026794,0.00024398186,0.0022801731,0.98762083,0.00029704458,0.005806082,0.00040578272],"about_ca_topic_score_codex":0.00009029063,"about_ca_topic_score_gemma":0.0000038301146,"teacher_disagreement_score":0.0050008246,"about_ca_system_score_codex":0.0001335287,"about_ca_system_score_gemma":0.00021728443,"threshold_uncertainty_score":0.9999138},"labels":[],"label_agreement":null},{"id":"W2187314669","doi":"10.1016/bs.mie.2015.09.003","title":"Analysis of Arrestin Recruitment to Chemokine Receptors by Bioluminescence Resonance Energy Transfer","year":2015,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Chemokine receptor; G protein-coupled receptor; Arrestin; Chemokine; Bioluminescence; Receptor; Cell biology; Troubleshooting; Biophysics; Chemistry; Energy transfer; Biology; Signal transduction; Biochemistry; Computer science","score_opus":0.07553339100302597,"score_gpt":0.40399089954057743,"score_spread":0.32845750853755146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2187314669","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.47925213,0.0034000569,0.5137643,0.00036261705,0.0017704099,0.0006357763,0.000056912777,0.000037071935,0.0007206774],"genre_scores_gemma":[0.17646484,0.0004691199,0.81976897,0.0015093464,0.00016780589,0.0005203655,0.00018702983,0.000093528564,0.0008189733],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.98831105,0.0070127533,0.0015678637,0.0017344261,0.00030153134,0.0010723767],"domain_scores_gemma":[0.9969413,0.0010068613,0.00028549536,0.001175725,0.0002309263,0.0003596893],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.008520204,0.0006672459,0.0017770369,0.0012678301,0.00006178085,0.000014324957,0.0009669725,0.0011871175,0.00025093975],"category_scores_gemma":[0.002967359,0.00067067816,0.00035335447,0.002502178,0.00041737943,0.0000122443,0.0002897342,0.00055888953,0.0000046376176],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086514774,0.00046662719,0.004515873,0.000015895597,0.00026401208,0.00002872962,0.0004115948,0.001628607,0.91083485,0.0012399463,0.0011967313,0.07853199],"study_design_scores_gemma":[0.0016942809,0.002244177,0.004296196,0.000055432898,0.00017593903,0.0000331295,0.00024382734,0.00035021786,0.9111288,0.0013322108,0.077669226,0.0007765676],"about_ca_topic_score_codex":0.0006760717,"about_ca_topic_score_gemma":0.00096046366,"teacher_disagreement_score":0.30600464,"about_ca_system_score_codex":0.00019934238,"about_ca_system_score_gemma":0.00018022182,"threshold_uncertainty_score":0.9995744},"labels":[],"label_agreement":null},{"id":"W2188252236","doi":"10.1111/bph.13398","title":"Integrating the GPCR transactivation‐dependent and biased signalling paradigms in the context of PAR1 signalling","year":2015,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Transactivation; G protein-coupled receptor; Signalling; Receptor; Cell biology; Biology; Second messenger system; Functional selectivity; Context (archaeology); Signal transduction; Agonist; G protein; Biochemistry; Gene expression; Gene","score_opus":0.044261723751515915,"score_gpt":0.32884897019231024,"score_spread":0.2845872464407943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2188252236","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010031602,0.98609185,0.0029193994,0.00006989687,0.00036444326,0.00045743934,0.000029824872,0.0000016834204,0.000033861088],"genre_scores_gemma":[0.16991772,0.8291739,0.000168918,0.00017790675,0.00047795646,0.000023147957,0.0000214086,0.000026873586,0.000012136784],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99709934,0.0010456982,0.0011102149,0.00022810415,0.00027398719,0.0002426718],"domain_scores_gemma":[0.99823755,0.0003264738,0.0010723912,0.00006732165,0.00023153072,0.00006470977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002904824,0.00024598202,0.0009444231,0.00009880197,0.000099319914,0.00006383076,0.0005559589,0.00026855632,0.00006347367],"category_scores_gemma":[0.00010334266,0.00016677126,0.00032954494,0.00014425111,0.00011455698,0.000011501857,0.000036993937,0.00079165987,4.173958e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008214744,0.0001249991,0.0000017395795,0.0008198949,0.00048782112,0.00017475088,0.0005200622,0.00020215775,0.07597794,0.000040449697,0.0007817627,0.92078626],"study_design_scores_gemma":[0.0048072245,0.0018686452,0.0000025772,0.012584419,0.0027957505,0.011421334,0.00465008,0.00035465203,0.10244759,0.00038461958,0.85763925,0.0010438344],"about_ca_topic_score_codex":0.00004615626,"about_ca_topic_score_gemma":0.00003310514,"teacher_disagreement_score":0.91974247,"about_ca_system_score_codex":0.00003375813,"about_ca_system_score_gemma":0.00037447497,"threshold_uncertainty_score":0.68007344},"labels":[],"label_agreement":null},{"id":"W2189098641","doi":"10.1016/s0898-6568(01)00259-5","title":"G protein specificity","year":2002,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":168,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"G protein; Receptor; G protein-coupled receptor; Pertussis toxin; Cell biology; Effector; Signal transduction; Biology; G beta-gamma complex; G alpha subunit; Protein subunit; Scaffold protein; Heterotrimeric G protein; Biochemistry","score_opus":0.04483234947529639,"score_gpt":0.2644662048778399,"score_spread":0.2196338554025435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2189098641","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007814805,0.9771325,0.020502914,0.0000017567733,0.00027781824,0.0007663907,0.000018372086,0.000033661287,0.0011884162],"genre_scores_gemma":[0.0001299074,0.99152076,0.0015810002,0.000013264956,0.001500518,0.000101747195,0.00043517564,0.00015008889,0.004567549],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9976564,0.00018372468,0.000622339,0.00082321576,0.00025101163,0.00046332847],"domain_scores_gemma":[0.998897,0.000014330733,0.00033627002,0.000536391,0.00006367469,0.00015231715],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00034560435,0.0005678121,0.0010044638,0.00010338045,0.00014538801,0.0000898914,0.0005168282,0.0007101404,0.0009826638],"category_scores_gemma":[0.00003391789,0.0005090039,0.0008174354,0.0001634546,0.000041979347,0.000002693373,0.00014822876,0.00040479278,0.00029433068],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005468797,0.00008069318,9.7114906e-8,0.0047819414,0.00024898216,0.00005334695,0.000019949506,0.000015783564,0.18964654,0.0001906981,0.00058601826,0.80437046],"study_design_scores_gemma":[0.00008311376,0.00008651346,1.5203153e-9,0.002700307,0.00015890195,0.000012456251,0.0000051641036,0.000034622004,0.053968128,0.000067471046,0.94231933,0.0005639632],"about_ca_topic_score_codex":0.0000019115896,"about_ca_topic_score_gemma":5.018739e-7,"teacher_disagreement_score":0.94173336,"about_ca_system_score_codex":0.000036563906,"about_ca_system_score_gemma":0.000095339485,"threshold_uncertainty_score":0.99993056},"labels":[],"label_agreement":null},{"id":"W2190061239","doi":"10.1016/j.neuron.2015.10.007","title":"Multi-Scale Molecular Deconstruction of the Serotonin Neuron System","year":2015,"lang":"en","type":"article","venue":"Neuron","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":220,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institute of Mental Health; Harvard NeuroDiscovery Center; Intellectual and Developmental Disabilities Research Center; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute on Drug Abuse; U.S. Public Health Service; National Institute on Aging","keywords":"Biology; Neuroscience; Neuron; Phenotype; Gene; Computational biology; Genetics","score_opus":0.014457441888785656,"score_gpt":0.22951419420965402,"score_spread":0.21505675232086838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2190061239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940687,0.000118244054,0.004562278,0.00003286039,0.0006562354,0.00019264674,0.00000472527,0.000012652166,0.00035168315],"genre_scores_gemma":[0.9982571,0.000005060395,0.0014353509,0.000078117366,0.00006249148,0.000010270264,0.0000068352238,0.000018594703,0.00012617123],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927396,0.00010289661,0.00015517054,0.00021092717,0.0001327789,0.00012427664],"domain_scores_gemma":[0.99946976,0.0000025586764,0.00009251699,0.0003102617,0.000066155764,0.00005873196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010797653,0.000095741736,0.00009547167,0.000016259386,0.0000360453,0.000010439044,0.00016662414,0.00008294074,0.000003911044],"category_scores_gemma":[0.00002770825,0.00007409335,0.0000818801,0.00005935817,0.00003486766,0.0000025632796,0.00008303977,0.00006876262,0.000005179034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001940701,0.000014768216,0.00097561156,0.000015468016,0.000005193631,0.0000011712648,0.000020310954,0.0006746807,0.9977216,0.00005342739,0.00008223855,0.0004161229],"study_design_scores_gemma":[0.00039056526,0.00015091902,0.0009706065,0.000014288257,0.000011733326,0.000036461577,0.000107583815,0.0015275409,0.9945032,0.0000070889214,0.0022037067,0.00007627985],"about_ca_topic_score_codex":0.000017546026,"about_ca_topic_score_gemma":0.0000063264224,"teacher_disagreement_score":0.0041884333,"about_ca_system_score_codex":0.000010694874,"about_ca_system_score_gemma":0.00004109467,"threshold_uncertainty_score":0.3021439},"labels":[],"label_agreement":null},{"id":"W2191750629","doi":"10.1021/acs.jafc.5b03749","title":"Calcium-Sensing Receptor (CaSR)-Mediated Anti-inflammatory Effects of <scp>l</scp>-Amino Acids in Intestinal Epithelial Cells","year":2015,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Advanced Foods and Materials Canada","keywords":"Calcium-sensing receptor; Chemistry; Receptor; Calcium; Inflammation; Tumor necrosis factor alpha; Cell culture; Endocrinology; Antagonist; Tryptophan; Secretion; Internal medicine; Amino acid; Pharmacology; Biochemistry; Parathyroid hormone; Biology; Medicine","score_opus":0.008577059656381544,"score_gpt":0.20142887971384693,"score_spread":0.19285182005746537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2191750629","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980542,0.0012649318,0.00016106083,0.000018784296,0.00028823857,0.00007192941,0.00000993371,0.0000046308483,0.00012630528],"genre_scores_gemma":[0.99825567,0.00018976929,0.00078103057,0.000017026181,0.0006059639,8.929849e-7,0.000023051096,0.000011542125,0.000115043404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880576,0.000045826702,0.0004944012,0.0001856299,0.00023310629,0.00023524734],"domain_scores_gemma":[0.99887,0.00006936584,0.00042869398,0.0000894527,0.0003208733,0.00022162632],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024271298,0.00020838511,0.00033977896,0.00003079984,0.00003080986,0.000025086507,0.00015057674,0.00023294293,0.0000035756773],"category_scores_gemma":[0.00032088897,0.00014057559,0.00013250473,0.000102758386,0.00006789801,0.000015159274,0.000061774415,0.0002599016,0.000001184992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026265894,0.00005207241,0.0006652781,0.0001377415,0.00005727348,0.0000124100225,0.0001955764,0.000043699998,0.997994,0.0000016190195,0.00060656504,0.00020746524],"study_design_scores_gemma":[0.0011318702,0.00060100335,0.0019789468,0.00018477984,0.000030608964,0.00025341744,0.0008213193,0.0000094055185,0.9942072,0.000023660734,0.00065368606,0.00010408902],"about_ca_topic_score_codex":0.0000031080187,"about_ca_topic_score_gemma":9.2859847e-7,"teacher_disagreement_score":0.0037868202,"about_ca_system_score_codex":0.000026214479,"about_ca_system_score_gemma":0.00007371237,"threshold_uncertainty_score":0.5732506},"labels":[],"label_agreement":null},{"id":"W219300997","doi":"10.1023/a:1021626825394","title":"Activation of Phospholipases A2 and D of a Human Neuroblastoma Cell Line (LA-N-2) by N-Dodecyl-l-Lysine Amide (Compound 24), a Putative G Protein Activator: Characteristics of Inhibition by (−)-Nicotine","year":2002,"lang":"en","type":"article","venue":"Neurochemical Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Activator (genetics); Lysine; Amide; Cell culture; Chemistry; Biochemistry; Neuroblastoma; Molecular biology; Biology; Amino acid; Receptor; Genetics","score_opus":0.030258336596496488,"score_gpt":0.29621763764766224,"score_spread":0.2659593010511657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W219300997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99883723,0.00015232727,0.0003449214,0.00006999846,0.0000104533265,0.0003218984,0.00013584977,0.0000052861433,0.00012205318],"genre_scores_gemma":[0.9991696,0.00016172994,0.0001427584,0.000019795485,0.00004211105,0.000025628233,0.00020280064,0.000031462274,0.00020414162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99826527,0.00020782885,0.0004466475,0.00038674482,0.00044006592,0.00025347475],"domain_scores_gemma":[0.9989131,0.0001437973,0.00026662883,0.00022314425,0.00034868653,0.000104624385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002699381,0.00016558151,0.00029768707,0.00008515798,0.000058098387,0.000016272304,0.00014294048,0.00016929382,0.00005920446],"category_scores_gemma":[0.0004578395,0.00016338921,0.00006772621,0.00022240919,0.00029844994,0.00001322413,0.00016643785,0.0003139807,6.384521e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027062857,0.00051499525,0.00003235895,0.00019288446,0.000016170025,0.0000012167767,0.0000680516,0.0000012137112,0.99723184,0.000021149424,0.0011226608,0.00052682724],"study_design_scores_gemma":[0.00071948534,0.0013365671,0.00003349531,0.000081633254,0.000008491993,0.0000027779554,0.00003459049,0.00025313173,0.99692076,0.00009067673,0.000405117,0.00011328465],"about_ca_topic_score_codex":0.000041263487,"about_ca_topic_score_gemma":4.633525e-7,"teacher_disagreement_score":0.0008215718,"about_ca_system_score_codex":0.000013691956,"about_ca_system_score_gemma":0.000025474403,"threshold_uncertainty_score":0.6662818},"labels":[],"label_agreement":null},{"id":"W2206930456","doi":"10.1074/jbc.m115.684357","title":"β-Arrestin-mediated Angiotensin II Signaling Controls the Activation of ARF6 Protein and Endocytosis in Migration of Vascular Smooth Muscle Cells","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; Université de Montréal","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Cell biology; Angiotensin II; Endocytosis; Guanine nucleotide exchange factor; G protein-coupled receptor; Signal transduction; Receptor; RAC1; Small GTPase; Biology; Endosome; Cell migration; Cell; Biochemistry","score_opus":0.019554048524663657,"score_gpt":0.22386285142648446,"score_spread":0.2043088029018208,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2206930456","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998241,0.0006813368,0.00080061046,0.00011500674,0.000022221911,0.00011466062,0.000005368276,0.0000015710483,0.000018236204],"genre_scores_gemma":[0.99880373,0.000097075346,0.00092781294,0.000031458585,0.00011368004,0.0000031321435,0.00001279308,0.000005323239,0.000005002098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99908787,0.00008307629,0.00043956775,0.00012300188,0.00015349874,0.00011297597],"domain_scores_gemma":[0.9990937,0.000049605827,0.00046685492,0.00009955791,0.0002271741,0.000063124375],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006543207,0.000102254504,0.00024532914,0.00002153184,0.000024843208,0.000007338552,0.00011851591,0.00018361256,0.000012569266],"category_scores_gemma":[0.00048512348,0.00006341476,0.00010567039,0.000081288046,0.000078900615,0.000006138297,0.00004598586,0.00013435105,7.466364e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001577844,0.00006734365,0.00046051608,0.000014312413,0.000027002407,0.0000015137322,0.000061662606,0.00027886764,0.99845386,0.000002130188,0.000027510685,0.00044751674],"study_design_scores_gemma":[0.00079537625,0.0003946878,0.0007667702,0.00007122275,0.00001255438,0.0000029454875,0.00022860925,0.00013786538,0.9968303,0.000106107684,0.0005824105,0.00007118905],"about_ca_topic_score_codex":0.000017518456,"about_ca_topic_score_gemma":9.88252e-7,"teacher_disagreement_score":0.0016235783,"about_ca_system_score_codex":0.000013629497,"about_ca_system_score_gemma":0.00006281443,"threshold_uncertainty_score":0.25859788},"labels":[],"label_agreement":null},{"id":"W2214302084","doi":"10.1007/978-1-60327-333-6_8","title":"Regulation of Dopamine Receptor Trafficking and Responsiveness","year":2009,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Receptor; Dopamine; Dopamine receptor; Cell biology; Endocytic cycle; Biology; D1-like receptor; G protein-coupled receptor; Dopamine receptor D2; 5-HT5A receptor; Dopamine receptor D1; Neuroscience; Signal transduction; Endocytosis; Biochemistry","score_opus":0.028673340811262087,"score_gpt":0.2428532324734789,"score_spread":0.21417989166221682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2214302084","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.046632208,0.043086845,0.0036026456,0.00002551068,0.0009871086,0.0016879406,0.000121385005,0.00010505788,0.9037513],"genre_scores_gemma":[0.11782932,0.0018362637,0.0010891369,0.00006514907,0.0010193962,0.000014951088,0.00031374738,0.00012676978,0.8777053],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99893177,0.00003159628,0.00032244867,0.00040241113,0.00016552566,0.00014626962],"domain_scores_gemma":[0.9991986,0.000013483395,0.0002724749,0.00034052978,0.000119190096,0.000055712426],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016779588,0.00025622986,0.0003068762,0.00007330706,0.000068724155,0.000022510361,0.00013541953,0.00038827327,0.00006860048],"category_scores_gemma":[0.000013597087,0.0002639936,0.0001098657,0.000002700339,0.00008526396,0.0000020829787,0.00007878461,0.00012097024,8.8813096e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026107777,0.000009115481,1.5634606e-7,0.000110781024,0.00010580161,0.000002205139,0.00009564084,0.000051703755,0.708835,0.041596692,0.00061410083,0.24831772],"study_design_scores_gemma":[0.00031540345,0.00030618437,0.000008512307,0.0002285186,0.000058852293,0.000006300613,0.0000057157927,0.00001727998,0.3620584,0.0008718631,0.63581693,0.00030604782],"about_ca_topic_score_codex":0.000008271171,"about_ca_topic_score_gemma":0.0000076001893,"teacher_disagreement_score":0.6352028,"about_ca_system_score_codex":0.000009918684,"about_ca_system_score_gemma":0.00003193214,"threshold_uncertainty_score":0.9999812},"labels":[],"label_agreement":null},{"id":"W2215904362","doi":"10.1371/journal.pone.0145688","title":"Thermostabilization of the Human Serotonin Transporter in an Antidepressant-Bound Conformation","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Government of Canada; National Institute of Mental Health; Howard Hughes Medical Institute","keywords":"Serotonin transporter; Serotonergic; Serotonin Plasma Membrane Transport Proteins; Reuptake; Transporter; Serotonin; Thermostability; Solute carrier family; Reuptake inhibitor; Biology; Antidepressant; Chemistry; Biophysics; Pharmacology; Biochemistry; Receptor; Neuroscience; Hippocampus; Enzyme; Gene","score_opus":0.05790578394045048,"score_gpt":0.2542268474670062,"score_spread":0.1963210635265557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2215904362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.999044,0.00005335201,0.00031771828,0.00001765069,0.000016226011,0.00020895063,0.0000048996803,0.0000035820733,0.00033361785],"genre_scores_gemma":[0.9996458,0.000010097187,0.0001558853,0.000036372177,0.000026766718,0.00000985724,0.00007120697,0.0000074104864,0.000036601683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995262,0.00004427687,0.00015089932,0.0000873678,0.00012156546,0.000069676884],"domain_scores_gemma":[0.9996729,0.0000013574629,0.00006131419,0.00016483417,0.00007545972,0.00002416548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016784755,0.00005029698,0.00007550782,0.000014787399,0.000022994238,0.0000065839813,0.00009398092,0.0000602495,0.00002837228],"category_scores_gemma":[0.000010247477,0.000038386213,0.00001963101,0.00004188583,0.000021623067,0.000008288541,0.0000123051705,0.000033857425,6.1940017e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014603374,0.00016107893,0.028838543,0.000016227272,0.000010913346,7.581557e-8,0.00046542558,0.00008032959,0.9702512,0.0000922344,0.0000041339736,0.00006521126],"study_design_scores_gemma":[0.00033804076,0.0001089419,0.008511749,0.000031256724,0.000010895667,2.050818e-7,0.00016532412,0.0004027219,0.990198,0.00015848714,0.000021180034,0.000053155745],"about_ca_topic_score_codex":0.000021151533,"about_ca_topic_score_gemma":0.000068085545,"teacher_disagreement_score":0.020326793,"about_ca_system_score_codex":0.000005887734,"about_ca_system_score_gemma":0.000025084191,"threshold_uncertainty_score":0.15653443},"labels":[],"label_agreement":null},{"id":"W2218990407","doi":"10.1016/j.bmcl.2015.12.050","title":"Salicylates are interference compounds in TR-FRET assays","year":2015,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; University of Victoria","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Michael Smith Health Research BC; Universities Space Research Association; National Cancer Research Institute","keywords":"Chemistry; Förster resonance energy transfer; Context (archaeology); Drug discovery; High-throughput screening; Computational biology; Combinatorial chemistry; Biophysics; Biochemistry; Fluorescence","score_opus":0.0216691796743399,"score_gpt":0.2403927361162143,"score_spread":0.2187235564418744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2218990407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947961,0.00072154135,0.0012548129,0.0021566425,0.0002716446,0.00009025648,0.000010113292,0.000027666905,0.00067122217],"genre_scores_gemma":[0.99744445,0.000036751433,0.0002678878,0.0012933337,0.0006439025,0.000011104696,0.000118976735,0.000032788244,0.00015077424],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985072,0.0000496023,0.00032513248,0.00047072733,0.00027064767,0.00037665933],"domain_scores_gemma":[0.99918455,0.000015266969,0.00013647489,0.0003561972,0.00006808274,0.0002394444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039227816,0.00025809527,0.00026961564,0.00003461929,0.000038340368,0.000030885763,0.00039459826,0.00020147141,0.00016253276],"category_scores_gemma":[0.0001673431,0.00024123183,0.0000696093,0.00015279344,0.00011626033,0.000006422369,0.00012441879,0.00024725377,0.000019207058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067450856,0.000036827572,0.0033076296,0.00003334443,0.000024880139,0.000035738147,0.00011889202,0.0000074770824,0.9865884,0.00000414862,0.009633336,0.00014183692],"study_design_scores_gemma":[0.0010324083,0.00007665083,0.0004364989,0.000107719075,0.000016372038,0.000081537524,0.00074354187,0.00004969505,0.99301296,0.000060651004,0.004073642,0.00030830616],"about_ca_topic_score_codex":0.000042676522,"about_ca_topic_score_gemma":0.000011539677,"teacher_disagreement_score":0.006424539,"about_ca_system_score_codex":0.00008633245,"about_ca_system_score_gemma":0.00010363583,"threshold_uncertainty_score":0.9837149},"labels":[],"label_agreement":null},{"id":"W2221273370","doi":"10.1016/j.neuroscience.2015.11.022","title":"Sox2 functionally interacts with βAPP, the βAPP intracellular domain and ADAM10 at a transcriptional level in human cells","year":2015,"lang":"en","type":"article","venue":"Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Centre National de la Recherche Scientifique; Thailand Research Fund; Mahidol University","keywords":"SOX2; ADAM10; Intracellular; Cell biology; Domain (mathematical analysis); Neuroscience; Biology; Chemistry; Gene; Genetics; Transcription factor; Metalloproteinase","score_opus":0.03680115432042481,"score_gpt":0.23616691800597514,"score_spread":0.19936576368555034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2221273370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917682,0.00012726539,0.0072467406,0.00024221808,0.00022795043,0.00012328979,0.000008227507,0.0000049418027,0.0002511632],"genre_scores_gemma":[0.9977893,0.000013770655,0.00050690694,0.00062810775,0.000073933494,0.000012753424,0.000008781829,0.0000095842615,0.0009568568],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906284,0.00005565991,0.00012299498,0.00034148854,0.00023068338,0.00018635482],"domain_scores_gemma":[0.9996715,0.00000851253,0.00004323473,0.00014637446,0.00004000672,0.00009033405],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029691093,0.00010779614,0.000074887896,0.00002921469,0.0001400199,0.000048917656,0.00017652562,0.000048167843,0.00001955311],"category_scores_gemma":[0.000019109542,0.00007369187,0.000022955943,0.00009471189,0.00016452043,0.000010686888,0.00006825609,0.000102153586,0.0000023466391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005888984,0.000028813272,0.00039063545,0.0000026122957,0.0000012525873,0.0000068678414,0.00014875538,0.00036743423,0.99820435,0.0004517366,0.00021632834,0.00012232024],"study_design_scores_gemma":[0.0009030831,0.0006899923,0.0057969242,0.000017801889,0.0000057179877,0.000100142606,0.0002407771,0.0004653833,0.9491311,0.0004690921,0.041960165,0.00021982461],"about_ca_topic_score_codex":0.000016295498,"about_ca_topic_score_gemma":0.00010988227,"teacher_disagreement_score":0.04907326,"about_ca_system_score_codex":0.000015574895,"about_ca_system_score_gemma":0.000070205264,"threshold_uncertainty_score":0.3005067},"labels":[],"label_agreement":null},{"id":"W2225075683","doi":"10.1161/res.115.suppl_1.176","title":"Abstract 176: Saxagliptin and Tadalafil Differentially Alter Global and Cellular Cardiac Function in a Translational Miniature Swine Model of Left Ventricle Hypertrophy","year":2014,"lang":"en","type":"article","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Gibson Energy (Canada)","funders":"","keywords":"Internal medicine; Contractility; Muscle hypertrophy; Ventricle; Heart failure; Medicine; Cardiology; Ejection fraction; Diastole; Pressure overload; Heart failure with preserved ejection fraction; Tadalafil; Cardiac function curve; Preload; Endocrinology; Blood pressure; Hemodynamics; Cardiac hypertrophy; Sildenafil","score_opus":0.02148821519640751,"score_gpt":0.27109606363999483,"score_spread":0.24960784844358733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2225075683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9878885,0.00053998583,0.011089192,0.00007134228,0.000044051685,0.00014457128,0.00001879597,0.0000027200922,0.00020084235],"genre_scores_gemma":[0.99940705,0.000038179092,0.00030515768,0.0000115697785,0.000104948114,0.000004937764,0.00008256759,0.000008448966,0.00003716116],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99906904,0.000096270596,0.00016688157,0.0002560812,0.00025220236,0.00015950625],"domain_scores_gemma":[0.99965554,0.000021842297,0.00003443017,0.00011865892,0.00010899229,0.000060536062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004846991,0.000077764846,0.00011682937,0.00006435226,0.00005950333,0.0000279923,0.000047446905,0.00013564578,0.000043986474],"category_scores_gemma":[0.000043206514,0.00007664756,0.000041333198,0.00007969733,0.000047353577,0.000008837389,0.000028802882,0.00010092077,0.0000011153634],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008607266,0.000025789672,0.02019572,0.00003586034,0.000015713144,2.213693e-7,0.000049431754,0.0046541677,0.97182345,0.00036013318,0.00002881684,0.0027246084],"study_design_scores_gemma":[0.0019767582,0.00022981525,0.6468282,0.000052872005,0.000029212,0.000003259265,0.00007813732,0.16569826,0.17882377,0.005438448,0.00052950357,0.00031180485],"about_ca_topic_score_codex":0.000031821186,"about_ca_topic_score_gemma":0.000014756537,"teacher_disagreement_score":0.7929997,"about_ca_system_score_codex":0.000010446039,"about_ca_system_score_gemma":0.000041060546,"threshold_uncertainty_score":0.31255966},"labels":[],"label_agreement":null},{"id":"W2225662698","doi":"10.1385/1-59259-184-1:075","title":"Steady-State Fluorescence Spectroscopy","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Alberta Heritage Foundation for Medical Research","keywords":"Fluorescence; Tryptophan; Fluorescence spectroscopy; Fluorescence correlation spectroscopy; Chemistry; Biological system; Biophysics; Fluorescence in the life sciences; Computer science; Computational biology; Nanotechnology; Biochemistry; Materials science; Biology; Physics; Amino acid; Optics","score_opus":0.025185201353660962,"score_gpt":0.25668150408717755,"score_spread":0.2314963027335166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2225662698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.64980674,0.0065858164,0.023434646,0.000009277233,0.0009015974,0.00067785074,0.000020976318,0.00009951291,0.3184636],"genre_scores_gemma":[0.9822776,0.00023793448,0.004303938,0.00013753105,0.00016084741,0.000032524444,0.000014549275,0.00004046684,0.012794645],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999074,0.000064243,0.00015150204,0.00031299677,0.000119354576,0.00027794842],"domain_scores_gemma":[0.99949723,0.000004028888,0.00005439658,0.00032754644,0.000038530896,0.000078263154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013724086,0.00014425689,0.00011158959,0.000019867639,0.00010397586,0.0000457262,0.00016718157,0.00007113921,0.00008052849],"category_scores_gemma":[0.000018278728,0.00013805997,0.00006869256,0.0000075725993,0.000047022582,0.0000018607251,0.000045202683,0.000082446204,0.000009798492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019591454,0.00001477118,0.0000064227347,0.000011301443,0.000024955076,0.0000049818814,0.000099219746,0.00002035815,0.9847623,0.011447605,0.000953242,0.0026352506],"study_design_scores_gemma":[0.00022389357,0.00010326879,0.000007286427,0.000008686053,0.000007219207,0.000004755872,0.000018834748,0.000017392556,0.85840046,0.00071796315,0.14033353,0.00015672353],"about_ca_topic_score_codex":0.000025310557,"about_ca_topic_score_gemma":0.000011399572,"teacher_disagreement_score":0.33247083,"about_ca_system_score_codex":0.0000076189317,"about_ca_system_score_gemma":0.000027748432,"threshold_uncertainty_score":0.5629922},"labels":[],"label_agreement":null},{"id":"W2233723355","doi":"10.3390/ijms17010095","title":"Transactivation of Epidermal Growth Factor Receptor by G Protein-Coupled Receptors: Recent Progress, Challenges and Future Research","year":2016,"lang":"en","type":"review","venue":"International Journal of Molecular Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":143,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Cure Brain Cancer Foundation","keywords":"Transactivation; G protein-coupled receptor; Receptor tyrosine kinase; Epidermal growth factor receptor; Biology; Signal transduction; Computational biology; Receptor; Cell biology; Bioinformatics; Transcription factor; Genetics; Gene","score_opus":0.052954542135850595,"score_gpt":0.35774884894795755,"score_spread":0.30479430681210695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2233723355","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002353544,0.9944925,0.00071501784,0.0011844957,0.00078266027,0.00036088342,0.000039117363,0.0000029559426,0.000068835536],"genre_scores_gemma":[0.0016899302,0.99567276,0.0017225888,0.000013514536,0.0007890019,0.000023738143,0.000021952621,0.000026810436,0.000039693037],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967984,0.0004876878,0.00078562397,0.00042102233,0.0012428208,0.00026442212],"domain_scores_gemma":[0.9974406,0.00006187524,0.0009461886,0.00013691276,0.001295353,0.00011909844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017523316,0.0002641964,0.0005951169,0.0003397777,0.000075533884,0.00007274145,0.0009202121,0.0003170007,0.0001263557],"category_scores_gemma":[0.0002078495,0.00017437701,0.00028473217,0.00016765133,0.00038224342,0.000035946185,0.00009834738,0.00029800466,0.0000020976192],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046987734,0.00006791739,9.980726e-7,0.0003521933,0.0002530805,0.000005673557,0.00006498909,1.293087e-7,0.0920109,0.0003991822,0.0001575598,0.9066404],"study_design_scores_gemma":[0.00030664823,0.0007661471,9.491741e-7,0.0034997247,0.000029569243,0.000066910485,0.00010075276,9.897659e-7,0.11318525,0.00029349176,0.88152426,0.00022529422],"about_ca_topic_score_codex":0.0000019071283,"about_ca_topic_score_gemma":5.2441874e-7,"teacher_disagreement_score":0.9064151,"about_ca_system_score_codex":0.000056754296,"about_ca_system_score_gemma":0.0004891973,"threshold_uncertainty_score":0.71108884},"labels":[],"label_agreement":null},{"id":"W2239816828","doi":"10.1007/978-0-387-79251-4_2","title":"Biomarkers in Schizophrenia","year":2008,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Endophenotype; Schizophrenia (object-oriented programming); Psychosis; Etiology; Schizophrenia research; Psychology; Neuroscience; Identification (biology); Cognition; Psychiatry; Clinical psychology; Medicine; Biology","score_opus":0.01204787195190861,"score_gpt":0.2139014580496729,"score_spread":0.20185358609776427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2239816828","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0042595696,0.0037882223,0.00043006922,0.000032785174,0.00030042863,0.00021568226,0.000016855542,0.000018974568,0.9909374],"genre_scores_gemma":[0.032657158,0.0061375485,0.0036363371,0.00033514074,0.00059626915,0.000012529002,0.00043383148,0.0001334077,0.9560578],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991023,0.000007595061,0.00022068148,0.00038773142,0.00011377885,0.00016789524],"domain_scores_gemma":[0.9995639,0.0000037504633,0.00006731175,0.0002752897,0.000029306362,0.00006047776],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007045067,0.00023421046,0.0001976982,0.00009252878,0.000030470397,0.00000991346,0.00015087274,0.0004890477,0.0011989706],"category_scores_gemma":[0.000007712055,0.00022173762,0.00014364182,0.000012809828,0.000042390213,8.5512545e-7,0.000078468154,0.00013199875,0.00008391506],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065062253,0.00005671514,0.00004015396,0.00006363619,0.0007735564,0.00018974271,0.000046694557,0.000033539778,0.8112414,0.030688023,0.10744029,0.048775613],"study_design_scores_gemma":[0.00073547394,0.00017293387,0.000010341787,0.0000720102,0.000014226412,0.000042179952,0.0000060563334,0.000014387882,0.080527864,0.0012473584,0.9165597,0.0005974612],"about_ca_topic_score_codex":0.000013816416,"about_ca_topic_score_gemma":0.000045293073,"teacher_disagreement_score":0.8091194,"about_ca_system_score_codex":0.000014461958,"about_ca_system_score_gemma":0.0000767955,"threshold_uncertainty_score":0.9997141},"labels":[],"label_agreement":null},{"id":"W22474514","doi":"10.1016/b978-0-12-394440-5.00011-5","title":"β-Arrestins in the Central Nervous System","year":2013,"lang":"en","type":"review","venue":"Progress in molecular biology and translational science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"","keywords":"G protein-coupled receptor; Central nervous system; Neuroscience; Biology; Internalization; Schizophrenia (object-oriented programming); Signal transduction; Receptor; Cell biology; Medicine; Genetics; Psychiatry","score_opus":0.02005367523352396,"score_gpt":0.3359713439602411,"score_spread":0.3159176687267171,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W22474514","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0033567643,0.9937112,0.0019238793,0.000043724714,0.00014480618,0.0006388385,0.000014366073,0.000005538582,0.0001609177],"genre_scores_gemma":[0.16527796,0.8304931,0.0034066807,0.000060700157,0.00013201582,0.0003990112,0.00020206746,0.000022365593,0.000006112928],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99826485,0.00026154882,0.00034253314,0.00055572833,0.00016572225,0.00040958976],"domain_scores_gemma":[0.99957144,0.000031483796,0.00010233272,0.0002038284,0.00003288903,0.00005799686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00075824105,0.00022844278,0.00035344705,0.00013728606,0.00011432756,0.000056769753,0.0005349617,0.00027983251,0.0000066883717],"category_scores_gemma":[0.000018812403,0.00014804986,0.00010075329,0.00037757392,0.0005629931,0.000006557702,0.00005874618,0.00022225922,0.0000023701205],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000073231163,0.000053281725,0.0020137094,0.00092726486,0.000024540823,0.000028778224,0.000077658835,0.000015121833,0.0012863273,0.03149602,0.000002813659,0.96406716],"study_design_scores_gemma":[0.002256213,0.0010030193,0.008234816,0.010001692,0.0004430717,0.0012966645,0.00041767218,0.0013268932,0.0030316464,0.0061037703,0.9623709,0.0035136903],"about_ca_topic_score_codex":0.000014201344,"about_ca_topic_score_gemma":0.000011936585,"teacher_disagreement_score":0.962368,"about_ca_system_score_codex":0.00001291611,"about_ca_system_score_gemma":0.00023648389,"threshold_uncertainty_score":0.60372984},"labels":[],"label_agreement":null},{"id":"W2250480428","doi":"","title":"GPRA and the asthma locus on chromosome 7p14-p15","year":2006,"lang":"en","type":"article","venue":"Työväentutkimus Vuosikirja","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Locus (genetics); Asthma; Genetics; Medicine; Biology; Gene; Immunology","score_opus":0.0032382032211327213,"score_gpt":0.19328755693675412,"score_spread":0.1900493537156214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2250480428","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98124164,0.0025430247,0.0009831003,0.0008663268,0.0003815426,0.00037831784,0.00001869083,0.00003898134,0.013548358],"genre_scores_gemma":[0.99548966,0.00021254962,0.00018971907,0.0008899201,0.0007733542,0.00003236583,0.000068981615,0.000035907113,0.0023075663],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869794,0.00009605529,0.00024430608,0.0004119693,0.0002140146,0.00033569318],"domain_scores_gemma":[0.9993523,0.00003458305,0.00009381975,0.0003976019,0.00004798605,0.00007373055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003311209,0.00023128555,0.00020740183,0.00003974743,0.00021646913,0.00007762212,0.00021940905,0.00015707781,0.0001626914],"category_scores_gemma":[0.00003292871,0.00015904171,0.00012276735,0.000088412526,0.00017963247,0.0000048372185,0.000112258385,0.00014281488,0.000054045704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006442302,0.00018006179,0.00021403498,0.000030587886,0.000102467886,0.00002065805,0.00011106039,0.0006475567,0.92423093,0.041648496,0.023864057,0.008305854],"study_design_scores_gemma":[0.004359518,0.0006449976,0.0005092106,0.000038106744,0.0000414512,0.00006989382,0.00009728414,0.0003404595,0.5580887,0.0031605398,0.4320847,0.00056513696],"about_ca_topic_score_codex":0.000103582606,"about_ca_topic_score_gemma":0.000024720539,"teacher_disagreement_score":0.40822065,"about_ca_system_score_codex":0.000014702594,"about_ca_system_score_gemma":0.000028947654,"threshold_uncertainty_score":0.64855325},"labels":[],"label_agreement":null},{"id":"W2256823787","doi":"10.1093/jb/mvv072","title":"Quantification of mutation-derived bias for alternate mating functionalities of the<i>Saccharomyces cerevisiae</i>Ste2p pheromone receptor","year":2015,"lang":"en","type":"article","venue":"The Journal of Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Plant Biotechnology Institute; Saskatchewan Research Council (Canada); University of Saskatchewan","funders":"Wayne State University","keywords":"Saccharomyces cerevisiae; G protein-coupled receptor; Mating; Biology; Signal transduction; Receptor; Signalling; Cell biology; Computational biology; Genetics; Gene","score_opus":0.04877810012263543,"score_gpt":0.2704350848093244,"score_spread":0.22165698468668896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2256823787","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906062,0.0017324232,0.006942201,0.00021369332,0.00028338563,0.00010817181,0.00003532656,0.0000018644192,0.00007675822],"genre_scores_gemma":[0.99743515,0.000112898415,0.0018119742,0.000027397407,0.00030688773,0.0000035986805,0.000022181559,0.0000134605425,0.0002664382],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894285,0.000082948674,0.00053420477,0.00009180433,0.00024858557,0.00009963008],"domain_scores_gemma":[0.9979751,0.00006528776,0.0011009822,0.00022271351,0.00059192895,0.00004400251],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009562424,0.000104317856,0.00018171723,0.000017078683,0.000057638175,0.000012259648,0.0003160936,0.0000809553,0.000026767028],"category_scores_gemma":[0.00034749584,0.000065514156,0.00016477527,0.00006674212,0.000089622925,0.000007920828,0.000044721677,0.000076783515,4.943703e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020896817,0.000030471814,0.00010135779,0.00008071202,0.00009513193,7.283914e-8,0.00020787962,0.0003632214,0.9976961,0.000037322876,0.00070618,0.00047258261],"study_design_scores_gemma":[0.00048108108,0.00015843454,0.000025610327,0.000110497225,0.00005147053,0.00003729246,0.0019356158,0.00007305807,0.99642026,0.00036245392,0.000273696,0.00007054818],"about_ca_topic_score_codex":0.000012489747,"about_ca_topic_score_gemma":6.9599423e-7,"teacher_disagreement_score":0.006828987,"about_ca_system_score_codex":0.000015067004,"about_ca_system_score_gemma":0.00014673376,"threshold_uncertainty_score":0.267159},"labels":[],"label_agreement":null},{"id":"W2264150533","doi":"10.1161/atvb.35.suppl_1.44","title":"Abstract 44: Organ-specific Stochastic Phenotype Switching is Required for Endothelial Health","year":2015,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Alberta","funders":"","keywords":"Biology; Von Willebrand factor; Phenotype; Cell biology; Endothelial stem cell; Homeostasis; Immunology; In vitro; Genetics; Platelet","score_opus":0.06640230416812877,"score_gpt":0.3036191285610244,"score_spread":0.23721682439289565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2264150533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91730016,0.00089064747,0.079941005,0.0005427606,0.0006228079,0.0005155839,0.00011871075,0.00003457371,0.000033722587],"genre_scores_gemma":[0.9928711,0.0015254861,0.003664618,0.0011123783,0.0005115678,0.000063554784,0.00018940495,0.000055602322,0.000006290226],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981879,0.00008551119,0.0004087905,0.0006920972,0.000116470605,0.00050920557],"domain_scores_gemma":[0.99901915,0.000025913383,0.00017868065,0.00040976456,0.0001081326,0.00025838788],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000639413,0.0002940014,0.00045016676,0.000059790495,0.00024913874,0.000069643094,0.0002055902,0.00024243539,0.000063627806],"category_scores_gemma":[0.000043654447,0.00026456814,0.00019970973,0.0000719677,0.00008000765,0.000012202095,0.0001131281,0.0000961023,0.000014620806],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018739533,0.00006617436,0.00038827088,0.000020889624,0.00014665726,1.2277849e-8,0.00045489002,0.000011395071,0.9944996,0.00049347966,0.0015097978,0.0023900555],"study_design_scores_gemma":[0.02761501,0.01728176,0.2051205,0.00068709644,0.00044990814,0.0000104016235,0.0051664524,0.0016462865,0.33638656,0.008737458,0.39097497,0.005923604],"about_ca_topic_score_codex":0.00006593644,"about_ca_topic_score_gemma":0.000023298711,"teacher_disagreement_score":0.65811306,"about_ca_system_score_codex":0.000030920917,"about_ca_system_score_gemma":0.0000984418,"threshold_uncertainty_score":0.9999806},"labels":[],"label_agreement":null},{"id":"W2265785703","doi":"10.1038/srep11133","title":"In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Universität Innsbruck; Tiroler Wissenschaftsförderung; Austrian Science Fund","keywords":"Protein-fragment complementation assay; G protein-coupled receptor; Effector; Biology; Luciferase; Bimolecular fluorescence complementation; Cell biology; Receptor; Zebrafish; Complementation; Kinase; Endogeny; Signal transduction; Protein–protein interaction; Protein kinase A; Computational biology; Chemistry; Transfection; Biochemistry; Yeast; Gene; Mutant","score_opus":0.02608380636204359,"score_gpt":0.25345134047352963,"score_spread":0.22736753411148602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2265785703","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931986,0.00011559705,0.0023247025,0.000009331936,0.0036307,0.00012772085,9.545101e-7,0.000004352658,0.0005880865],"genre_scores_gemma":[0.99901694,0.0000047344283,0.00038063677,0.000005453086,0.000109701905,0.000008370465,0.000022019458,0.0000076507085,0.00044451235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903774,0.000040911214,0.0003542331,0.00026977248,0.00017060863,0.00012672516],"domain_scores_gemma":[0.9991615,0.000006412279,0.00030703028,0.00030010962,0.00017990619,0.00004505319],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007515578,0.000067149835,0.00011063769,0.000090975576,0.00004895636,0.000014400867,0.000053122592,0.00006189492,0.000040522114],"category_scores_gemma":[0.00010422548,0.00006563161,0.000058394773,0.00024979847,0.0000406212,0.000012902405,0.000041935593,0.000045988632,7.5360146e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000326606,0.000045318404,0.00029522667,0.000008658793,0.000009161126,0.000006957919,0.00010967853,0.0049383584,0.9933413,0.000008622504,0.00078201026,0.00042203814],"study_design_scores_gemma":[0.00008618589,0.00010896849,0.000035325458,0.000022767668,0.0000054661155,0.000055697314,0.00013523827,0.00019616635,0.98701054,0.0007658643,0.011517606,0.00006016437],"about_ca_topic_score_codex":0.0000757505,"about_ca_topic_score_gemma":0.000046856007,"teacher_disagreement_score":0.010735596,"about_ca_system_score_codex":0.000021326701,"about_ca_system_score_gemma":0.00010345487,"threshold_uncertainty_score":0.26763794},"labels":[],"label_agreement":null},{"id":"W2265939051","doi":"10.1139/y02-167","title":"Pharmacological characterization of putative β<sub>1</sub>-β<sub>2</sub>-adrenergic receptor heterodimers","year":2003,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"Heart and Stroke Foundation of Canada","keywords":"Receptor; G protein-coupled receptor; HEK 293 cells; Ligand (biochemistry); Chemistry; Intrinsic activity; Rhodopsin-like receptors; Functional selectivity; Biology; Agonist; Biochemistry; Cell biology; Metabotropic receptor","score_opus":0.009831354595312727,"score_gpt":0.2364638636402654,"score_spread":0.22663250904495266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2265939051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970626,0.0006545612,0.00030645123,0.000117888405,0.0015787221,0.00016582182,0.000072036106,0.000003439247,0.000038467395],"genre_scores_gemma":[0.9973706,0.0010877282,0.000095846204,0.00088635844,0.00040732799,0.000011536646,0.000107286665,0.00002418479,0.000009120834],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808186,0.0005663153,0.0005044803,0.00032030407,0.000081254955,0.00044580858],"domain_scores_gemma":[0.9986461,0.00004843141,0.00047907865,0.00008489218,0.00027194302,0.0004695891],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000381272,0.0002508131,0.0004489965,0.00018569188,0.0001643709,0.000009637633,0.00018449657,0.00034502512,0.00040011227],"category_scores_gemma":[0.000048938684,0.0002324104,0.00016360963,0.00013816115,0.00034508272,0.000019898378,0.000023774852,0.00033457344,0.0000061103656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026343434,0.000049233433,0.00013538304,0.00002878175,0.00031377733,0.000021492413,0.00012591806,0.00018863326,0.9966391,0.00007518653,0.00052570924,0.0016333859],"study_design_scores_gemma":[0.0011377209,0.0010684262,0.00066521694,0.000010141889,0.00012747351,0.00009984217,0.00004697933,0.000026471209,0.99305683,0.00022083704,0.0033177405,0.00022230198],"about_ca_topic_score_codex":0.000013284369,"about_ca_topic_score_gemma":0.000029584662,"teacher_disagreement_score":0.0035822163,"about_ca_system_score_codex":0.000040619365,"about_ca_system_score_gemma":0.0005281708,"threshold_uncertainty_score":0.9477421},"labels":[],"label_agreement":null},{"id":"W22681252","doi":"10.2174/138955712800959143","title":"国際患者安全目標(IPSG)の達成に向けて--医療安全管理室の取り組み (特集 患者安全と医療の質改善は\"医療の根幹\" JCI受審の決断から組織が変化するまでのプロセス--NTT東日本関東病院のチャレンジ)","year":2011,"lang":"en","type":"article","venue":"看護管理","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Computer science","score_opus":0.026609172380755157,"score_gpt":0.2113233417691742,"score_spread":0.18471416938841903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W22681252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9289005,0.001900566,0.0114911245,0.00014104202,0.0015829565,0.00047480952,0.000050630482,0.00014636863,0.055312008],"genre_scores_gemma":[0.98779774,0.00029608543,0.0054540504,0.0007516176,0.0007027918,0.00005061991,0.00013166993,0.000089417925,0.004726008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99784374,0.00009471299,0.0004155959,0.000724558,0.0002812479,0.00064015266],"domain_scores_gemma":[0.99865,0.000013725006,0.00015163288,0.0007869593,0.00013291062,0.0002647765],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00037613368,0.00037602612,0.00031146585,0.00009071871,0.00020431337,0.000049036258,0.0005311713,0.00036963448,0.0025760294],"category_scores_gemma":[0.00007896284,0.000350813,0.00027667347,0.00017315827,0.00009817143,0.000012530544,0.00023200341,0.00020865488,0.00032315965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017771476,0.00022159242,0.001505885,0.000033936998,0.00015880054,0.000035025438,0.0005259084,0.000014905213,0.9714186,0.004280486,0.013536289,0.008090855],"study_design_scores_gemma":[0.00076948653,0.0005663093,0.0009435664,0.000030608207,0.00004862985,0.000047385052,0.00030313453,0.00006331574,0.8416163,0.0015752901,0.15340142,0.0006345487],"about_ca_topic_score_codex":0.0001411535,"about_ca_topic_score_gemma":0.000048428185,"teacher_disagreement_score":0.13986513,"about_ca_system_score_codex":0.00002329457,"about_ca_system_score_gemma":0.00009614045,"threshold_uncertainty_score":0.9998944},"labels":[],"label_agreement":null},{"id":"W2268839964","doi":"10.1096/fasebj.22.1_supplement.1231.2","title":"Hemorrhage induced inactivation of presynaptic group III mGluRs controls metaplasticity in circuits regulating fluid balance","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Glutamatergic; Neuroscience; Long-term potentiation; Hypothalamus; Chemistry; Stimulation; Internal medicine; Homeostasis; Endocrinology; Biology; Glutamate receptor; Medicine; Receptor","score_opus":0.018243718107849295,"score_gpt":0.22732557774134893,"score_spread":0.20908185963349962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2268839964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9822008,0.00024515452,0.017085345,0.000032085194,0.00013961099,0.00012813482,0.000002534987,0.0000036927536,0.00016266541],"genre_scores_gemma":[0.9992502,0.000045700457,0.00039936882,0.000048296348,0.00019033987,0.000005320554,0.0000074000527,0.000012419253,0.000040961157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998967,0.00015547225,0.0003444007,0.00014289116,0.00018575489,0.00020449907],"domain_scores_gemma":[0.9994062,0.00004852497,0.00025802522,0.00015803808,0.0000769579,0.000052231608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005435747,0.000113938004,0.0001994174,0.00004969463,0.00015517944,0.000014403445,0.00018502714,0.00009207499,0.000039925042],"category_scores_gemma":[0.00018963766,0.00008440655,0.000083275605,0.00010053589,0.00004510141,0.00001186051,0.000037422215,0.0002109576,8.9339466e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000090218105,0.00003471406,0.00073289813,0.000005915858,0.000035256315,0.000008615811,0.00012282166,0.00074350106,0.99716973,0.00008946374,0.000010337428,0.0009565252],"study_design_scores_gemma":[0.0011305636,0.00023327584,0.0028742687,0.00003122394,0.000016914959,0.00024584262,0.00016209153,0.0032830092,0.9917629,0.00015272069,0.000008980397,0.00009825986],"about_ca_topic_score_codex":0.000023053142,"about_ca_topic_score_gemma":0.0000056500785,"teacher_disagreement_score":0.017049419,"about_ca_system_score_codex":0.000025530371,"about_ca_system_score_gemma":0.00005500903,"threshold_uncertainty_score":0.34419993},"labels":[],"label_agreement":null},{"id":"W2269706043","doi":"10.1096/fasebj.22.1_supplement.724.3","title":"MAPPING THE LIGAND INTERACTION OF THE AT1 –RECEPTOR WITH PHOTOPROBES IN ALL POSITIONS OF ANGIOTENSIN II","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Photoaffinity labeling; Receptor; Chemistry; Angiotensin II; Stereochemistry; Ligand (biochemistry); Angiotensin II receptor type 1; Biochemistry","score_opus":0.021871103861970727,"score_gpt":0.22911124241885017,"score_spread":0.20724013855687945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2269706043","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980995,0.00029421627,0.0007048269,0.0005790036,0.000120556244,0.00009740967,0.0000044398776,0.0000010623711,0.00009899398],"genre_scores_gemma":[0.999137,0.00017512945,0.00030306095,0.00013785307,0.000111766334,0.0000020001185,0.0000031057039,0.0000069295024,0.00012317245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994558,0.000080901285,0.00018054464,0.000067571076,0.000114229406,0.000100963676],"domain_scores_gemma":[0.9995665,0.000013999438,0.00017250425,0.00015125175,0.00007752861,0.000018241131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023577662,0.00006763903,0.000085747095,0.000026389473,0.00021717462,0.000008005275,0.0001757688,0.00003942396,0.000029682442],"category_scores_gemma":[0.00001623114,0.000029909468,0.00008650914,0.00009224809,0.000092646485,0.0000047327967,0.000051149662,0.00016250841,4.4822553e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005958073,0.000031134776,0.00054996077,0.0000019425695,0.00004669131,9.840406e-7,0.0010331705,0.000426486,0.99739635,0.000017003831,0.00027576688,0.00016091243],"study_design_scores_gemma":[0.00023738941,0.00016265642,0.0011462289,0.00007160679,0.000011578906,0.00031625538,0.00077857927,0.00007017879,0.99639386,0.00004651866,0.0007215737,0.00004354759],"about_ca_topic_score_codex":0.000036708774,"about_ca_topic_score_gemma":0.000022740587,"teacher_disagreement_score":0.0010374913,"about_ca_system_score_codex":0.000009414739,"about_ca_system_score_gemma":0.000047440764,"threshold_uncertainty_score":0.16703536},"labels":[],"label_agreement":null},{"id":"W2273105472","doi":"10.1096/fasebj.22.1_supplement.812.3","title":"Transmembrane domain 1 of human dopamine D1 and D5 receptors is a crucial structural determinant for ligand affinity and selectivity","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Receptor; Dopamine receptor; Transmembrane domain; Ligand (biochemistry); Chemistry; Biology; Biochemistry","score_opus":0.015258541751248737,"score_gpt":0.24998554947106494,"score_spread":0.2347270077198162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2273105472","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99786496,0.000600483,0.0011777463,0.000070385475,0.00010387476,0.00014256884,0.000022053004,0.0000023316418,0.000015588255],"genre_scores_gemma":[0.99835604,0.00033513602,0.0009024372,0.000040556333,0.00028046628,0.0000032586793,0.000005035872,0.000012379823,0.00006469415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993005,0.00006553514,0.00020347527,0.00015567614,0.00009823711,0.0001765787],"domain_scores_gemma":[0.9996222,0.000023024353,0.00012141554,0.00009200115,0.00006216452,0.00007916399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033381273,0.00012386737,0.00018703785,0.000028621449,0.0005388169,0.000028026268,0.00009970685,0.0000846912,0.000022806584],"category_scores_gemma":[0.00002198501,0.00008328068,0.000083070045,0.000036089594,0.00018200846,0.0000069794983,0.000028352448,0.00012426003,6.900336e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018406565,0.000012200391,0.00082896405,0.00001892641,0.00003818252,0.0000026526873,0.00064284354,0.0000023648206,0.9963031,0.0000192932,0.000045629942,0.0019017955],"study_design_scores_gemma":[0.0010239185,0.00082553056,0.0011821024,0.000018460842,0.0000274973,0.00062100997,0.00012367421,0.00003254225,0.99522626,0.00062508055,0.00017875647,0.000115172355],"about_ca_topic_score_codex":0.000011498002,"about_ca_topic_score_gemma":0.00002394983,"teacher_disagreement_score":0.0017866232,"about_ca_system_score_codex":0.000005935388,"about_ca_system_score_gemma":0.00004756791,"threshold_uncertainty_score":0.41441986},"labels":[],"label_agreement":null},{"id":"W2273830512","doi":"10.1371/journal.pone.0142826","title":"Differential Regulation of 6- and 7-Transmembrane Helix Variants of μ-Opioid Receptor in Response to Morphine Stimulation","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institute of Neurological Disorders and Stroke; Pfizer Canada; Canada Excellence Research Chairs, Government of Canada; National Institutes of Health; National Institute of Dental and Craniofacial Research; Louise and Alan Edwards Foundation; Pfizer","keywords":"Stimulation; Opioid receptor; G protein-coupled receptor; Opioid; Signal transduction; Receptor; Morphine; Chemistry; Pharmacology; μ-opioid receptor; Transmembrane domain; Intracellular; Cell biology; Neuroscience; Biology; Biochemistry","score_opus":0.029780276525288526,"score_gpt":0.23820968276438229,"score_spread":0.20842940623909376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2273830512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971026,0.00007332901,0.002493398,0.00007045521,0.000026751777,0.00019777706,0.00001694269,0.0000031133357,0.000015609065],"genre_scores_gemma":[0.99587876,0.000028160433,0.0038553965,0.000011320964,0.000049679056,0.000006173156,0.000048838076,0.000010236875,0.00011146002],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993106,0.000074385214,0.00021821776,0.0001542059,0.00015909338,0.00008346479],"domain_scores_gemma":[0.9996241,0.000013140935,0.000066039844,0.00012974384,0.000106838546,0.000060149097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023606722,0.000070612085,0.00016170746,0.0000708838,0.000009148963,0.000003972491,0.00004950435,0.000084525316,0.00006629411],"category_scores_gemma":[0.0001232818,0.000070654736,0.000018579016,0.00007802246,0.000016047967,0.0000042865668,0.000027943026,0.000030140438,0.0000011685554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020630884,0.00023893686,0.00096392166,0.000047144506,0.000027778395,1.4435186e-7,0.00021636943,0.00025802836,0.99590784,0.000020661519,0.000008756901,0.00024732103],"study_design_scores_gemma":[0.00090461783,0.00055865763,0.013605496,0.00009182925,0.000017865772,2.6883743e-7,0.000020464771,0.001356045,0.9832425,0.00011542953,0.0000133718495,0.00007341933],"about_ca_topic_score_codex":0.000022540802,"about_ca_topic_score_gemma":0.000007535033,"teacher_disagreement_score":0.012665315,"about_ca_system_score_codex":0.000007946235,"about_ca_system_score_gemma":0.000029989911,"threshold_uncertainty_score":0.28812164},"labels":[],"label_agreement":null},{"id":"W2274515300","doi":"10.1016/s0022-3565(24)35340-6","title":"Pharmacological Characterization of Endogenous Acetylcholine Release from Primary Septal Cultures","year":2000,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute","funders":"","keywords":"Acetylcholine; Muscarinic acetylcholine receptor; Oxotremorine; Extracellular; Endocrinology; Veratridine; Internal medicine; Muscarinic acetylcholine receptor M3; Choline; Chemistry; Agonist; Endogeny; Cholinergic; Muscarinic acetylcholine receptor M1; Muscarinic acetylcholine receptor M2; Biology; Receptor; Biochemistry; Medicine","score_opus":0.02029617683775329,"score_gpt":0.3007617179370477,"score_spread":0.2804655410992944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2274515300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928791,0.0063132,0.00013293103,0.000086079046,0.00033112735,0.00009410773,0.000026894115,0.0000034485993,0.00013309627],"genre_scores_gemma":[0.992196,0.004644524,0.0004732016,0.0019574952,0.0005732297,0.0000031857062,0.0000534191,0.000012406222,0.00008651269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917597,0.00010962351,0.00034185295,0.00013151963,0.00010725912,0.0001337744],"domain_scores_gemma":[0.9996089,0.0000119933375,0.00021222394,0.000043980184,0.000056342305,0.000066566085],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011480542,0.00013052858,0.0002224397,0.00002667153,0.00006359695,0.000008809965,0.00012257553,0.00013659146,0.0015087425],"category_scores_gemma":[0.0000012083498,0.000104599596,0.00012754716,0.000034548077,0.00009403783,0.0000126507875,0.00003077754,0.00014123814,0.0000017644397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014567586,0.00035525154,0.000043448596,0.000004549971,0.0003889432,0.0000127426565,0.00028895237,0.000033293985,0.9924607,0.0000032417506,0.00012572593,0.0048263455],"study_design_scores_gemma":[0.001800432,0.00079450145,0.00009497277,0.0000057266,0.00012932664,0.00010200045,0.00007783114,0.000044113356,0.98230976,0.000013818171,0.014522767,0.00010474871],"about_ca_topic_score_codex":0.0000016823897,"about_ca_topic_score_gemma":6.144551e-8,"teacher_disagreement_score":0.014397041,"about_ca_system_score_codex":0.00001600053,"about_ca_system_score_gemma":0.00004307435,"threshold_uncertainty_score":0.999404},"labels":[],"label_agreement":null},{"id":"W2274840413","doi":"10.1002/pro.2902","title":"A comparative study of rhodopsin function in the great bowerbird (<scp><i>P</i></scp><i>tilonorhynchus nuchalis</i>): Spectral tuning and light‐activated kinetics","year":2016,"lang":"en","type":"article","venue":"Protein Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of South Carolina","keywords":"Rhodopsin; Biology; Visual phototransduction; Mutagenesis; Genetics; Vertebrate; Evolutionary biology; Function (biology); Biophysics; Mutation; Gene; Biochemistry","score_opus":0.019380535044554323,"score_gpt":0.256422500630835,"score_spread":0.23704196558628066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2274840413","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99628544,0.0001691088,0.002196874,0.00006736944,0.000062246814,0.0006548135,0.000002425182,0.000007910683,0.00055381097],"genre_scores_gemma":[0.99928063,0.000013050969,0.00047255814,0.00003132044,0.00005152781,0.000047412843,9.943969e-7,0.000007714272,0.00009481],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986293,0.00013654582,0.00022788013,0.00041974004,0.0003081593,0.00027840887],"domain_scores_gemma":[0.9993788,0.00004299965,0.00013385357,0.00027660799,0.00010932133,0.000058407706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007441792,0.00014492663,0.00016941872,0.00008764029,0.0001256408,0.00005241401,0.0003164953,0.000054553308,0.0000062339536],"category_scores_gemma":[0.00016902768,0.00008534341,0.00002659399,0.00038477065,0.00021690562,0.000023338265,0.00010509354,0.0000816671,0.0000013696858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003620159,0.00012538188,0.0007358071,0.0000048574802,0.0000075916923,0.0000017896233,0.0016178442,0.000009611541,0.996691,0.00015445582,0.000019517194,0.0005959598],"study_design_scores_gemma":[0.00061968673,0.0016232505,0.0036129095,0.00004339024,0.000008102262,0.0000076086517,0.0029417668,0.000041907886,0.990322,0.0003113913,0.00039953794,0.00006843503],"about_ca_topic_score_codex":0.00004485211,"about_ca_topic_score_gemma":0.00006532398,"teacher_disagreement_score":0.006368969,"about_ca_system_score_codex":0.000017795057,"about_ca_system_score_gemma":0.00004933873,"threshold_uncertainty_score":0.34802034},"labels":[],"label_agreement":null},{"id":"W2277254272","doi":"10.1016/j.cellsig.2016.02.013","title":"PSD-95 regulates CRFR1 localization, trafficking and β-arrestin2 recruitment","year":2016,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Ottawa","funders":"","keywords":"Cell biology; Signal transducing adaptor protein; Biology; Signal transduction","score_opus":0.024138995051834353,"score_gpt":0.2361992088533231,"score_spread":0.21206021380148876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2277254272","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.59116244,0.005734513,0.40246424,0.00010255902,0.00018402039,0.0002331949,0.0000030815997,0.000034297955,0.00008163544],"genre_scores_gemma":[0.9957973,0.001113002,0.002076334,0.000102989055,0.0003456848,0.000025600491,0.000036700272,0.00004199558,0.00046040653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877685,0.00006613125,0.00026406083,0.00045166575,0.00015397987,0.00028731176],"domain_scores_gemma":[0.9994605,0.00002794838,0.00009772619,0.00020718755,0.000087008724,0.00011960494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032869665,0.0001914748,0.00016091946,0.000036023004,0.00017153949,0.000050313563,0.00013134946,0.00015430221,0.00015023994],"category_scores_gemma":[0.0000584293,0.00014541908,0.00007069153,0.00006951857,0.00006103956,0.0000074906943,0.00006817579,0.000049896174,0.000011067467],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022088878,0.000017815637,0.00022520023,0.000016697968,0.000031880507,0.000005391751,0.00005292817,0.0007349187,0.9842157,0.0003064657,0.00023609422,0.014134849],"study_design_scores_gemma":[0.00042603762,0.00012284674,0.000012067283,0.00012025014,0.000021453805,0.00000784927,0.000048113936,0.0025166501,0.96719813,0.0006655185,0.028605014,0.00025604197],"about_ca_topic_score_codex":0.000004079654,"about_ca_topic_score_gemma":0.000002419788,"teacher_disagreement_score":0.40463483,"about_ca_system_score_codex":0.000015590318,"about_ca_system_score_gemma":0.00003485899,"threshold_uncertainty_score":0.5930018},"labels":[],"label_agreement":null},{"id":"W2277553727","doi":"10.71781/31077","title":"Functional Analysis of Nuclear beta-Adrenergic Receptors in the Myocardium","year":2012,"lang":"en","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Institut de Cardiologie de Montréal; Natural Sciences and Engineering Research Council of Canada; McGill University; Heart and Stroke Foundation of Canada","keywords":"Adrenergic receptor; BETA (programming language); Receptor; Internal medicine; Endocrinology; Medicine; Computer science","score_opus":0.006225033061474753,"score_gpt":0.17411385112343872,"score_spread":0.16788881806196396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2277553727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97649324,0.008762561,0.00007057636,0.000037884245,0.00082884467,0.00015413834,0.000038636463,0.000010327289,0.013603818],"genre_scores_gemma":[0.9891769,0.00032914008,0.000113258524,0.00006207086,0.00020206625,0.0000122186275,0.0023808891,0.000020969586,0.0077024447],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984993,0.00013774188,0.0003122601,0.00036431916,0.00044409535,0.00024232459],"domain_scores_gemma":[0.99912184,0.000022642294,0.00028884783,0.00034184544,0.0001389946,0.00008584128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002825066,0.0002447189,0.00034515274,0.0003245481,0.0009990402,0.000017608576,0.0003175821,0.00040378998,0.00019782875],"category_scores_gemma":[0.0000171859,0.00022149035,0.00055151584,0.00044607162,0.00007082004,0.000013122686,0.000059611702,0.0002094031,0.000007432567],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017485303,0.0004540499,0.015227684,0.0001090852,0.0060942927,0.00011678911,0.015622821,0.01670586,0.92202604,0.015283688,0.0039673974,0.002643744],"study_design_scores_gemma":[0.00206172,0.00047044645,0.39925322,0.00015846659,0.009054008,0.00019734756,0.07125005,0.0007489295,0.2535182,0.00015415352,0.26137358,0.001759877],"about_ca_topic_score_codex":0.0032956796,"about_ca_topic_score_gemma":0.0023877856,"teacher_disagreement_score":0.6685079,"about_ca_system_score_codex":0.00037315144,"about_ca_system_score_gemma":0.0003155592,"threshold_uncertainty_score":0.9032114},"labels":[],"label_agreement":null},{"id":"W2279631816","doi":"10.1074/jbc.m115.686907","title":"Post-endocytotic Deubiquitination and Degradation of the Metabotropic γ-Aminobutyric Acid Receptor by the Ubiquitin-specific Protease 14","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Grantová Agentura České Republiky; Canada Research Chairs","keywords":"Cell biology; Internalization; Ubiquitin; Ubiquitin ligase; Chemistry; Metabotropic receptor; Protease-activated receptor 2; Enzyme-linked receptor; Biology; Biochemistry; Receptor; Agonist","score_opus":0.015157343192643488,"score_gpt":0.22274696895231258,"score_spread":0.2075896257596691,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2279631816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99390984,0.0027997352,0.0022062475,0.0007738173,0.000098767014,0.00012622394,0.00003323715,0.0000028039913,0.000049332335],"genre_scores_gemma":[0.99808294,0.0008438485,0.00043669093,0.00008029024,0.00022528926,0.0000071270783,0.000011941337,0.000007802146,0.0003040989],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898624,0.00012252688,0.00038814158,0.00016814379,0.00018195875,0.00015300824],"domain_scores_gemma":[0.99895597,0.00005294951,0.00048441303,0.00017528403,0.0002664369,0.000064958986],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003929662,0.00013171558,0.00017782884,0.000010811031,0.0000867423,0.00001874636,0.00028306874,0.00016047688,0.00014125371],"category_scores_gemma":[0.0004102915,0.000053845906,0.00014567045,0.00006185327,0.00016482297,0.0000087672715,0.00008961894,0.0001340576,8.821887e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009624205,0.00003710697,0.00050632004,0.000012634174,0.00002894768,5.2923485e-7,0.000008445329,6.2423146e-7,0.9912463,0.000033318847,0.00038534406,0.0076441853],"study_design_scores_gemma":[0.00045723663,0.000238819,0.000572559,0.000037833677,0.000017489998,0.000072622504,0.00007265426,0.0000014184593,0.9924672,0.00011949162,0.0058574574,0.00008518642],"about_ca_topic_score_codex":7.4832826e-7,"about_ca_topic_score_gemma":1.3427497e-7,"teacher_disagreement_score":0.007558999,"about_ca_system_score_codex":0.00002117305,"about_ca_system_score_gemma":0.000042461757,"threshold_uncertainty_score":0.21957724},"labels":[],"label_agreement":null},{"id":"W2280436805","doi":"10.2174/1568026615666150701113344","title":"Exploring the Technology Landscape of 7TMR Drug Signaling Profiling","year":2015,"lang":"en","type":"review","venue":"Current Topics in Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SNC-Lavalin (Canada)","funders":"","keywords":"Drug discovery; Functional selectivity; G protein-coupled receptor; Receptor; Second messenger system; Signal transduction; Computational biology; Transmembrane protein; Arrestin; G protein; Transmembrane domain; Biology; Chemistry; Cell biology; Bioinformatics; Biochemistry","score_opus":0.10618270123454349,"score_gpt":0.3442090782645119,"score_spread":0.23802637702996843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2280436805","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008758489,0.98969185,0.00009822007,0.000026149068,0.00075710117,0.00029608342,0.000012968086,0.0000136811805,0.00034542504],"genre_scores_gemma":[0.0012199722,0.99647105,0.00021656623,0.000004542039,0.0015306477,0.00016477778,0.00021872115,0.00003967821,0.00013404027],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99809355,0.00006938039,0.0007192778,0.00047443254,0.0003165011,0.00032686556],"domain_scores_gemma":[0.9988679,0.000032727527,0.00035997696,0.00053150835,0.00012673791,0.000081100814],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00078053575,0.0003589519,0.00089323317,0.00009265525,0.000049073773,0.00001241055,0.00067875965,0.00028365478,0.00003126865],"category_scores_gemma":[0.00023360833,0.0002517414,0.00022745547,0.00032787534,0.00012020909,0.0000041038757,0.00025591784,0.0008202061,0.0000020602959],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010569029,0.00006135854,0.00005959608,0.013513134,0.00007858662,0.000009164431,0.00008978912,0.000014030778,0.005901105,0.00009386787,0.00027418663,0.97989464],"study_design_scores_gemma":[0.00024790593,0.000035733003,1.7943478e-7,0.007775443,0.0001747047,0.000034620884,0.00043147954,0.000010548609,0.05969731,0.0001478265,0.9311253,0.00031896686],"about_ca_topic_score_codex":0.0000017860978,"about_ca_topic_score_gemma":6.556392e-7,"teacher_disagreement_score":0.97957563,"about_ca_system_score_codex":0.00004841484,"about_ca_system_score_gemma":0.0003885056,"threshold_uncertainty_score":0.9999935},"labels":[],"label_agreement":null},{"id":"W2282261023","doi":"10.1007/978-1-4419-9194-2_33","title":"Platelet Activating Factor Receptors","year":2003,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Heart Institute; Hôpital Maisonneuve-Rosemont; Hôpital Fleurimont; Université de Sherbrooke; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Intracrine; Receptor; Cell biology; Intracellular; Platelet-activating factor; G protein-coupled receptor; Cell surface receptor; Chemistry; Signal transduction; Cell; Lipid signaling; Biology; Biochemistry; Autocrine signalling; Immunology","score_opus":0.023461134105905872,"score_gpt":0.3340266789172824,"score_spread":0.3105655448113765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2282261023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9664524,0.029642578,0.0005171858,0.000042069452,0.0005302181,0.000101071964,0.0000013804608,0.000006759424,0.0027062956],"genre_scores_gemma":[0.9957827,0.0025553938,0.0011298233,0.00027934436,0.00014512888,0.000017355349,0.000023854716,0.000009753122,0.000056689787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925125,0.000065190085,0.00017331792,0.00027923647,0.000036114936,0.00019487184],"domain_scores_gemma":[0.99977034,0.00002467881,0.000053374974,0.00008897598,0.000010812588,0.000051838626],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000097981065,0.0001274572,0.00016209792,0.00004217117,0.000047393303,0.0000027522622,0.00005931798,0.000102867234,0.00025174147],"category_scores_gemma":[0.00009396811,0.00009577764,0.000019268147,0.000057222212,0.00012565954,0.000007714728,0.00002893361,0.000072033545,0.0000012731552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029517523,0.000021626,0.0016099882,0.0000037968728,0.0000058716646,9.777214e-7,0.00017071882,0.000001921678,0.98114884,0.001335632,0.000032645596,0.015638474],"study_design_scores_gemma":[0.00060491904,0.00066861406,0.00002280388,0.000017254111,4.6291566e-7,0.000012314862,0.0014190116,0.0000029406694,0.8059061,0.0003141219,0.19092384,0.000107573345],"about_ca_topic_score_codex":0.0000107420865,"about_ca_topic_score_gemma":0.0000051668935,"teacher_disagreement_score":0.19089119,"about_ca_system_score_codex":0.000010375393,"about_ca_system_score_gemma":0.000009601696,"threshold_uncertainty_score":0.3905699},"labels":[],"label_agreement":null},{"id":"W2283432493","doi":"10.1038/srep18198","title":"Structural and functional interactions between six-transmembrane μ-opioid receptors and β2-adrenoreceptors modulate opioid signaling","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; Pfizer Canada; Canada Excellence Research Chairs, Government of Canada; National Institute of Dental and Craniofacial Research; Louise and Alan Edwards Foundation; Pfizer","keywords":"Receptor; Opioid; Pharmacology; Signal transduction; Chemistry; Opioid receptor; Transmembrane protein; Hyperalgesia; Cell biology; Transmembrane domain; Neuroscience; Biology; Nociception; Biochemistry","score_opus":0.021827788067271703,"score_gpt":0.24655286477921937,"score_spread":0.22472507671194766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2283432493","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99077636,0.0006129949,0.0017385801,0.000051180574,0.006445667,0.00019971027,0.000009011624,0.0000304894,0.00013597902],"genre_scores_gemma":[0.99600154,0.00001850207,0.0014188907,0.000023376597,0.0004940735,0.000011582225,0.00045348075,0.000026854823,0.001551702],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99799645,0.000059478167,0.0004385502,0.00085248944,0.00034083257,0.00031219848],"domain_scores_gemma":[0.9989171,0.000017385002,0.0001940516,0.00033784934,0.00020435006,0.0003292727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00077051355,0.00022645076,0.00021969338,0.00012372773,0.00037530946,0.00026453106,0.00007597163,0.00013356796,0.0001980252],"category_scores_gemma":[0.000093940514,0.00020605106,0.00008160425,0.00016745305,0.00022975121,0.00003516962,0.00010704234,0.00014960219,0.0000042259067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033602497,0.000013133032,0.01454488,0.000025481011,0.000067693734,0.00001083526,0.00042453755,0.00046769704,0.97728044,0.000030647538,0.0024888872,0.0046121674],"study_design_scores_gemma":[0.0005165589,0.00019015324,0.0019982383,0.000056246532,0.00007440105,0.0003541107,0.00054937106,0.00044911,0.9255237,0.0050791525,0.064628184,0.00058079127],"about_ca_topic_score_codex":0.00003863769,"about_ca_topic_score_gemma":0.000022357228,"teacher_disagreement_score":0.0621393,"about_ca_system_score_codex":0.000026745533,"about_ca_system_score_gemma":0.00012524103,"threshold_uncertainty_score":0.8402518},"labels":[],"label_agreement":null},{"id":"W2285959938","doi":"10.1093/ijnp/pyv108","title":"Methadone Reverses Analgesic Tolerance Induced by Morphine Pretreatment","year":2015,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Centre National de la Recherche Scientifique; Université de Strasbourg; Institut National de la Santé et de la Recherche Médicale","keywords":"Morphine; Pharmacology; μ-opioid receptor; Drug tolerance; Agonist; Opioid; Analgesic; Chemistry; DAMGO; Methadone; Opiate; Enkephalin; Receptor; Opioid receptor; Medicine; Internal medicine","score_opus":0.029727714758008478,"score_gpt":0.3159558296152032,"score_spread":0.2862281148571947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2285959938","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99153686,0.0010315528,0.00088937755,0.0029940524,0.003189719,0.00008340383,0.000009396481,0.000003774468,0.00026188898],"genre_scores_gemma":[0.995126,0.0004779105,0.00034464535,0.0027542408,0.00093803956,0.0000044250273,0.0000077956265,0.000015583704,0.00033137595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989539,0.00015205852,0.00030831367,0.00014405254,0.00031462085,0.00012706353],"domain_scores_gemma":[0.99905133,0.000028464106,0.0003070696,0.0001139549,0.00039454174,0.00010465333],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000381254,0.000116943986,0.0001406596,0.000054762113,0.00002978125,0.000022977387,0.00058933476,0.000052543743,0.00012963491],"category_scores_gemma":[0.00007733015,0.00008029869,0.00009986885,0.00006201771,0.000037291975,0.000009320972,0.00007223888,0.00016796082,0.000008795486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008053057,0.00010143462,0.000071433344,7.4763693e-7,0.00021931241,0.00005128991,0.000047093105,0.00034851604,0.9561298,0.000017723778,0.040205378,0.0020019582],"study_design_scores_gemma":[0.004050346,0.0016697377,0.0002760038,0.000013522718,0.000084953055,0.00082778523,0.00008603439,0.00016745753,0.88692,0.00037426874,0.10536026,0.00016967914],"about_ca_topic_score_codex":0.000009354622,"about_ca_topic_score_gemma":0.0000011267887,"teacher_disagreement_score":0.06920986,"about_ca_system_score_codex":0.000031854936,"about_ca_system_score_gemma":0.00008049502,"threshold_uncertainty_score":0.32744858},"labels":[],"label_agreement":null},{"id":"W2287114519","doi":"10.1074/jbc.m115.684308","title":"Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Office of Extramural Research, National Institutes of Health; National Institute of General Medical Sciences; European Regional Development Fund; National Institutes of Health; Consejería de Sanidad, Comunidad de Madrid; Canadian HIV Trials Network, Canadian Institutes of Health Research; European Commission; Instituto de Salud Carlos III; Canadian Institutes of Health Research; Comunidad de Madrid; Fundación Ramón Areces","keywords":"Heterotrimeric G protein; G protein-coupled receptor; Effector; Protein kinase C; Cell biology; G protein-coupled receptor kinase; Biology; Signal transduction; G protein; Scaffold protein; Gq alpha subunit; G beta-gamma complex; Chemistry","score_opus":0.02090648640222365,"score_gpt":0.2420566211828856,"score_spread":0.22115013478066195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2287114519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891667,0.000061000523,0.010300661,0.00017464909,0.000055945206,0.00009394842,0.000009655203,0.0000034447498,0.00013401292],"genre_scores_gemma":[0.9980324,0.000015172145,0.0012244174,0.000059976846,0.00032842564,0.000007011966,0.0000066630487,0.000009779528,0.00031616582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991621,0.000025672118,0.00029692453,0.00019307257,0.00015598943,0.0001662745],"domain_scores_gemma":[0.9991852,0.00003600149,0.0003193642,0.00012452809,0.00018375128,0.00015117708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022050213,0.0001397748,0.00021857378,0.000027215314,0.000027669494,0.000010488099,0.00016054694,0.00017167923,0.00015812267],"category_scores_gemma":[0.000408054,0.000070433074,0.00013804261,0.00006775872,0.000050379615,0.000006034968,0.0000621379,0.000108364926,0.0000034789894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013956473,0.00010004616,0.00039187341,0.000021787833,0.000057793386,0.000022446124,0.0000061351225,0.0000063388525,0.9966304,0.0000085420415,0.00012589345,0.0012331221],"study_design_scores_gemma":[0.0008467552,0.0016081992,0.00024503237,0.00031103462,0.00000986078,0.0003470909,0.000026622743,7.511864e-7,0.9945032,0.000023317776,0.001956696,0.00012141767],"about_ca_topic_score_codex":0.0000011748032,"about_ca_topic_score_gemma":1.8365574e-7,"teacher_disagreement_score":0.009076244,"about_ca_system_score_codex":0.000028760891,"about_ca_system_score_gemma":0.00008026821,"threshold_uncertainty_score":0.28721774},"labels":[],"label_agreement":null},{"id":"W2289311083","doi":"10.1096/fasebj.22.1_supplement.952.6","title":"Prolonged amelioration of LV dysfunction after withdrawal of chronic CNS blockade of AT <sub>1</sub> receptors in rats with CHF post MI","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Losartan; Blockade; Medicine; Internal medicine; Receptor; Ligation; Angiotensin II; Endocrinology; Cardiology","score_opus":0.00560192537481011,"score_gpt":0.189979325813288,"score_spread":0.1843774004384779,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2289311083","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99847966,0.000556631,0.00063609617,0.000042522635,0.000114852366,0.00014098804,0.000007129562,0.0000017302298,0.000020385309],"genre_scores_gemma":[0.99936855,0.00026654953,0.00013613391,0.000015205962,0.00014115915,0.0000052686983,0.000018720253,0.000014797906,0.00003360983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990836,0.0001057492,0.0003298331,0.0001254874,0.00020506239,0.00015028664],"domain_scores_gemma":[0.99927247,0.0000086267955,0.0003477652,0.00015522621,0.00017499716,0.000040929113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027890137,0.00011168836,0.00017534458,0.00007239858,0.0000702409,0.000004471137,0.00010417359,0.0000962984,0.00005865629],"category_scores_gemma":[0.000020160156,0.00007531151,0.00007906278,0.00012470594,0.00012376618,0.000009127537,0.000032253924,0.00014121567,0.0000010566099],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010856428,0.00006981625,0.004155267,0.000019866875,0.000050748276,0.000004602785,0.00037949538,0.00090496324,0.9926386,0.0000017076319,0.000035328507,0.0006539869],"study_design_scores_gemma":[0.00078064506,0.0015214222,0.0034128304,0.000080232916,0.000027026883,0.000120003395,0.00013847678,0.00006788182,0.9937358,0.000010567795,0.000021437618,0.00008370137],"about_ca_topic_score_codex":0.0000142737845,"about_ca_topic_score_gemma":0.00013555514,"teacher_disagreement_score":0.0014516059,"about_ca_system_score_codex":0.000036231217,"about_ca_system_score_gemma":0.00016433754,"threshold_uncertainty_score":0.3071114},"labels":[],"label_agreement":null},{"id":"W2289739275","doi":"10.1096/fasebj.23.1_supplement.790.4","title":"Striatal interneurons in dissociated culture","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Striatum; Neuroscience; Cholinergic neuron; Cholinergic; Interneuron; GABAergic; Parvalbumin; Calretinin; Biology; Glutamatergic; Medium spiny neuron; Ganglionic eminence; Axon; Glutamate receptor; Dopamine; Inhibitory postsynaptic potential; Receptor","score_opus":0.009048566656631741,"score_gpt":0.24385517010240912,"score_spread":0.2348066034457774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2289739275","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978548,0.00026966515,0.00084862247,0.00030164685,0.00016252299,0.00004384112,0.000004124287,0.0000035585226,0.0005111771],"genre_scores_gemma":[0.99853873,0.0001536382,0.00008610265,0.0003213595,0.0002967133,5.505946e-7,0.0000125508,0.0000053466642,0.0005850316],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994645,0.00007036641,0.0001332554,0.00008807067,0.000086222884,0.00015758578],"domain_scores_gemma":[0.9997715,0.0000034444163,0.00006167824,0.000092679955,0.000023500203,0.00004723773],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022410002,0.00007416399,0.000069896516,0.000018585133,0.00008191087,0.000044747245,0.000188312,0.00006158921,0.00006610451],"category_scores_gemma":[0.00004134806,0.00004610014,0.000072165734,0.00005131282,0.000012937434,0.0000030149909,0.000022464712,0.00021848528,0.0000050141125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003635555,0.00002418312,0.0002480698,3.0687963e-7,0.000010647248,0.0000055085325,0.00014737374,0.00006161997,0.99652976,0.00006676262,0.0009927215,0.0018767107],"study_design_scores_gemma":[0.00057136803,0.00035532506,0.0014956354,0.000018723807,0.000009137274,0.00007914666,0.00031627738,0.000054923887,0.9937472,0.00078772666,0.0024583996,0.00010617103],"about_ca_topic_score_codex":0.0000028012525,"about_ca_topic_score_gemma":0.0000067057254,"teacher_disagreement_score":0.0027825753,"about_ca_system_score_codex":0.000012116556,"about_ca_system_score_gemma":0.000023919016,"threshold_uncertainty_score":0.1879909},"labels":[],"label_agreement":null},{"id":"W2290767627","doi":"10.1096/fasebj.23.1_supplement.943.8","title":"Purification and partial characterization of a novel, non‐AT1, non‐AT2 binding site for angiotensins in the rat brain","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Chemistry; Isoelectric point; Cyanogen bromide; Binding site; Biochemistry; Binding protein; Gel electrophoresis; Peptide; Chromatography; Peptide sequence; Enzyme","score_opus":0.014398330095388464,"score_gpt":0.24663511136281538,"score_spread":0.23223678126742692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2290767627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9328407,0.000046363508,0.06561063,0.0012106058,0.00008241822,0.00018501753,0.000014008945,0.0000010882127,0.0000091361935],"genre_scores_gemma":[0.99859095,0.00007835759,0.00050491706,0.0004125423,0.00029448533,0.0000037464129,0.000070687296,0.000006066871,0.00003825705],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994671,0.00004463709,0.0001832553,0.00009713865,0.00008288811,0.00012498538],"domain_scores_gemma":[0.9996565,0.000014194204,0.0001465567,0.00010708439,0.00005082704,0.000024851133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006550335,0.00007151517,0.00008429734,0.000036012934,0.00012927433,0.000049595437,0.0001042989,0.000059600028,0.000004116031],"category_scores_gemma":[0.000037172318,0.000044002663,0.000053782598,0.000066935274,0.000021125965,0.000008244924,0.000009964007,0.00007977672,3.994758e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007065282,0.00003048961,0.00007585916,0.000002584784,0.000007334344,5.0920687e-7,0.00039315346,0.000040449075,0.99689555,0.000037911585,0.000063530286,0.0023819578],"study_design_scores_gemma":[0.0006000597,0.00025797437,0.0026907735,0.000022666061,0.000014815533,0.000054548047,0.000117993804,0.0025052982,0.9930675,0.0000260805,0.0005789048,0.00006335795],"about_ca_topic_score_codex":0.0000020305783,"about_ca_topic_score_gemma":0.0000018382284,"teacher_disagreement_score":0.06575021,"about_ca_system_score_codex":0.000005478917,"about_ca_system_score_gemma":0.00002555101,"threshold_uncertainty_score":0.17943765},"labels":[],"label_agreement":null},{"id":"W2292371489","doi":"10.1096/fasebj.23.1_supplement.1017.45","title":"Beta‐arrestin and vasomotor control in the spontaneously hypertensive rat","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Endocrinology; Internal medicine; Vasomotor; Hindlimb; Receptor; Phenylephrine; Desensitization (medicine); Neuropeptide Y receptor; Chemistry; G protein-coupled receptor; Medicine; Bradykinin; Blood pressure; Neuropeptide","score_opus":0.008696100500609474,"score_gpt":0.21805492332757612,"score_spread":0.20935882282696663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2292371489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99492854,0.0016782436,0.00097005005,0.0019708138,0.00014490636,0.00013396198,0.0000025898396,0.0000023349548,0.00016853794],"genre_scores_gemma":[0.9955567,0.00022519914,0.0001416999,0.0035516229,0.00042779488,0.0000020230025,0.0000026584387,0.0000061680034,0.0000861139],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925864,0.00017752471,0.00014691401,0.000110154164,0.00012129688,0.00018544903],"domain_scores_gemma":[0.9996533,0.000041324256,0.000066403234,0.00014385882,0.000044748947,0.00005039672],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005701153,0.00009939416,0.00011324621,0.000019634343,0.0001735833,0.00007180479,0.00020577839,0.00004834692,0.00002721371],"category_scores_gemma":[0.00005093174,0.000051169023,0.00006014168,0.00003648386,0.000036220936,0.0000030917893,0.000012864793,0.00020794508,0.0000028819054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105365754,0.00001909491,0.00015085134,7.132202e-7,0.00001693084,0.00017055252,0.00014885908,0.000060993672,0.9959861,0.000096539865,0.0006201426,0.0026238565],"study_design_scores_gemma":[0.005121286,0.0025281878,0.004396888,0.00008616992,0.0001861095,0.029032357,0.0027406847,0.0010721709,0.93550205,0.0036394827,0.015111862,0.00058277627],"about_ca_topic_score_codex":0.000005909246,"about_ca_topic_score_gemma":0.000010172286,"teacher_disagreement_score":0.060484074,"about_ca_system_score_codex":0.000005945023,"about_ca_system_score_gemma":0.00003279838,"threshold_uncertainty_score":0.20866123},"labels":[],"label_agreement":null},{"id":"W2292818168","doi":"10.1021/acschemneuro.5b00271","title":"Binding Interactions of Dopamine and Apomorphine in D2High and D2Low States of Human Dopamine D2 Receptor Using Computational and Experimental Techniques","year":2015,"lang":"en","type":"article","venue":"ACS Chemical Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Bilim Akademisi; Max-Planck-Gesellschaft","keywords":"Apomorphine; Dopamine; Dopamine receptor D2; Dopamine receptor; Neuroscience; Dopamine receptor D3; Dopamine receptor D1; Chemistry; Pharmacology; Dopaminergic; Psychology; Medicine","score_opus":0.030750022173928207,"score_gpt":0.30735847307193076,"score_spread":0.27660845089800257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2292818168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99860644,0.0001361371,0.0011109099,0.000022480997,0.000034252083,0.00006796752,0.0000114765735,0.000003511829,0.000006820163],"genre_scores_gemma":[0.99573225,0.000027274968,0.004155735,0.00002744195,0.000017988914,0.0000027369663,0.000020374717,0.0000060793436,0.00001014713],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994098,0.000016659593,0.00017595252,0.00021450412,0.00009369658,0.00008939752],"domain_scores_gemma":[0.99974984,0.000018571518,0.000076835524,0.000055649685,0.00003880676,0.00006028727],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011009616,0.000077452285,0.00011727474,0.000049346283,0.000028786519,0.000013128931,0.00005770842,0.00003316952,0.0000022747256],"category_scores_gemma":[0.00005826328,0.00007283788,0.000009936626,0.00008069528,0.0002369045,0.000015241461,0.00013560809,0.000049219376,2.1206423e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020171636,0.000043840893,0.0012785366,0.000009325502,0.0000010707219,4.6305172e-7,0.000055078308,0.000033517947,0.99834967,0.000025061045,0.000007997677,0.00017529719],"study_design_scores_gemma":[0.0002642348,0.00020911628,0.000056148005,0.000025569396,0.0000022116621,0.000022459344,0.0001098308,0.0013625,0.99773955,0.00006253173,0.000075430915,0.00007040979],"about_ca_topic_score_codex":0.000026524414,"about_ca_topic_score_gemma":9.634123e-7,"teacher_disagreement_score":0.003044825,"about_ca_system_score_codex":0.000007760147,"about_ca_system_score_gemma":0.000013149502,"threshold_uncertainty_score":0.29702425},"labels":[],"label_agreement":null},{"id":"W2292909888","doi":"10.1111/bph.13474","title":"The G‐protein biased partial κ opioid receptor agonist 6′‐GNTI blocks hippocampal paroxysmal discharges without inducing aversion","year":2016,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institute on Drug Abuse; Austrian Science Fund","keywords":"Pharmacology; Agonist; Neuroscience; Anticonvulsant; Hippocampal formation; Medicine; Partial agonist; Receptor; Epilepsy; Psychology; Internal medicine","score_opus":0.009943486523930371,"score_gpt":0.2530410461233861,"score_spread":0.24309755959945575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2292909888","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915963,0.0017345172,0.0033622927,0.0010870593,0.0019438481,0.00019364305,0.000028611012,0.000008610351,0.000045139597],"genre_scores_gemma":[0.9946192,0.0014395126,0.00066323584,0.00021783839,0.0023103866,0.00001506886,0.000008908326,0.000029208299,0.0006966383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982016,0.0003225182,0.00052427687,0.00027007886,0.00023915831,0.000442355],"domain_scores_gemma":[0.9990031,0.00005697103,0.00044509763,0.000099174395,0.00021865625,0.00017700331],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009080098,0.00017642112,0.00025909574,0.00004349353,0.0004250592,0.000087696666,0.00039838935,0.00018963171,0.0008739556],"category_scores_gemma":[0.00016262919,0.0001257251,0.00021148137,0.000063822445,0.00018322928,0.000018750387,0.00011815314,0.0002760169,0.000013201391],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044341045,0.00006313099,0.000259963,0.0000058332516,0.00011967371,0.000050114788,0.000023648114,0.0000062184063,0.9476713,0.000013350943,0.012795719,0.038547643],"study_design_scores_gemma":[0.0019912615,0.00051626243,0.000057613805,0.0001084744,0.000049850496,0.00046481835,0.000073435585,0.0000145609865,0.9007322,0.00007992558,0.095729716,0.00018188253],"about_ca_topic_score_codex":0.000019658031,"about_ca_topic_score_gemma":0.000010621885,"teacher_disagreement_score":0.082934,"about_ca_system_score_codex":0.000037710965,"about_ca_system_score_gemma":0.00019619548,"threshold_uncertainty_score":0.95692015},"labels":[],"label_agreement":null},{"id":"W2293372802","doi":"10.3109/10799893.2015.1072976","title":"Selective disruption of dopamine D2-receptors/beta-arrestin2 signaling by mood stabilizers","year":2015,"lang":"en","type":"article","venue":"Journal of Receptors and Signal Transduction","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec","funders":"Canadian Institutes of Health Research","keywords":"Dopamine receptor D2; Dopamine; Neuroscience; BETA (programming language); Mood; Dopamine receptor; Receptor; Dopamine receptor D3; Psychology; Pharmacology; Medicine; Internal medicine; Psychiatry; Computer science","score_opus":0.015611555772138774,"score_gpt":0.24744240608895648,"score_spread":0.23183085031681772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2293372802","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9632354,0.0018742619,0.033852506,0.00008767681,0.00073266844,0.00014731321,0.000008692596,0.0000047329368,0.000056797588],"genre_scores_gemma":[0.9971121,0.0005146534,0.0018402297,0.000010945667,0.00036537036,0.000003884849,0.000028882347,0.000025609166,0.0000983431],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982946,0.00019201628,0.0006930033,0.00025071928,0.0003508052,0.00021888586],"domain_scores_gemma":[0.99890274,0.00002834451,0.00042860865,0.00008788168,0.00036594013,0.00018648055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010069322,0.00020409656,0.00038710856,0.00015706499,0.000047427766,0.000023969431,0.00011499896,0.00018641219,0.000108440036],"category_scores_gemma":[0.000058689246,0.00017705328,0.00016474423,0.0002152815,0.00008504015,0.00004245675,0.000013534016,0.00023268946,4.864836e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000641596,0.00014491359,0.0026787003,0.00003231191,0.00008132972,8.11804e-7,0.00044251126,0.0020075515,0.9846446,0.000016771299,0.0006168758,0.008692025],"study_design_scores_gemma":[0.0016983632,0.0021591673,0.000086814245,0.00008432289,0.00006524914,0.000053750802,0.001700506,0.00012556995,0.9879271,0.00018050405,0.0056950604,0.00022359192],"about_ca_topic_score_codex":0.00003238579,"about_ca_topic_score_gemma":0.000009817731,"teacher_disagreement_score":0.03387673,"about_ca_system_score_codex":0.00005278471,"about_ca_system_score_gemma":0.000110416186,"threshold_uncertainty_score":0.7220023},"labels":[],"label_agreement":null},{"id":"W2297494845","doi":"10.1002/cne.23991","title":"Developmental and adult expression patterns of the G‐protein‐coupled receptor GPR88 in the rat: Establishment of a dual nuclear–cytoplasmic localization","year":2016,"lang":"en","type":"article","venue":"The Journal of Comparative Neurology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; Douglas College","funders":"","keywords":"Biology; In situ hybridization; Striatum; Nucleus accumbens; Neocortex; Orphan receptor; Neuroscience; Amygdala; Cell biology; Forebrain; Internal medicine; Endocrinology; Central nervous system; Gene expression; Genetics; Medicine","score_opus":0.011466825288825392,"score_gpt":0.22857991761658328,"score_spread":0.21711309232775788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2297494845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964646,0.000087014385,0.0025346589,0.00063224667,0.000087466804,0.00017099541,0.00000418375,6.420917e-7,0.000018199025],"genre_scores_gemma":[0.9994727,0.00011687199,0.00008947048,0.00025493032,0.00004375059,0.000002565424,9.1342014e-7,0.0000059041445,0.000012888097],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875206,0.0005518839,0.00035087884,0.000086024025,0.0001586952,0.000100485886],"domain_scores_gemma":[0.9992655,0.00007721196,0.00040978758,0.00010102397,0.00012724838,0.000019254654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041194074,0.00009070896,0.0001790678,0.000031485124,0.000055855624,0.000005414853,0.00023656417,0.000059887745,0.000040303905],"category_scores_gemma":[0.000048512604,0.000036986352,0.000045422206,0.000054432625,0.00011350871,0.000008588779,0.00009025609,0.00011465528,4.283486e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006984947,0.000044644694,0.0017394418,0.000005515479,0.000015941025,6.8582364e-7,0.0011390866,0.00011665053,0.9957603,0.0001262855,0.0002390492,0.00011389782],"study_design_scores_gemma":[0.00093288365,0.0008732028,0.0025352216,0.000062688436,0.0000122161555,0.00007359953,0.00069020974,0.00010489832,0.99361604,0.00014954915,0.0008976416,0.000051846848],"about_ca_topic_score_codex":0.0000066254715,"about_ca_topic_score_gemma":0.000019662395,"teacher_disagreement_score":0.0030081125,"about_ca_system_score_codex":0.0000056365634,"about_ca_system_score_gemma":0.000041370295,"threshold_uncertainty_score":0.15082598},"labels":[],"label_agreement":null},{"id":"W2300170789","doi":"10.1074/jbc.m115.696039","title":"Positive Allosteric Modulation of the Glucagon-like Peptide-1 Receptor by Diverse Electrophiles","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"","keywords":"Allosteric regulation; Chemistry; Biochemistry; Allosteric modulator; Receptor; Peptide; Cell biology; Biology","score_opus":0.010437968584767632,"score_gpt":0.21784708123772636,"score_spread":0.20740911265295872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2300170789","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977524,0.00041052085,0.00127682,0.00022096926,0.00012961621,0.000048733084,0.000037360194,0.0000022859567,0.000121276724],"genre_scores_gemma":[0.9985124,0.00044326318,0.0002916041,0.00008541085,0.00025133195,0.0000012914414,0.00001411969,0.000007354785,0.00039321443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991623,0.00005959142,0.0003216833,0.00015502416,0.00014775748,0.00015362207],"domain_scores_gemma":[0.99918437,0.00002771798,0.00041406887,0.00014140991,0.00016737611,0.00006508028],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001790716,0.00012209445,0.00017724547,0.000008485637,0.000046329616,0.0000073510278,0.0002688113,0.00019882713,0.00021079057],"category_scores_gemma":[0.00013927858,0.000058174326,0.00021656102,0.000052858853,0.00010418438,0.0000056066756,0.00009382665,0.00009596707,0.0000015573052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016869449,0.00004899078,0.0007894513,0.0000053452072,0.00005128622,7.978108e-7,0.000007675827,0.0000047334133,0.9957098,0.0000041062635,0.001729134,0.0014799933],"study_design_scores_gemma":[0.00036994438,0.00033926085,0.0007427942,0.000045134144,0.000012163936,0.00003004674,0.00003921846,0.0000025290042,0.9947143,0.000107335996,0.0035019238,0.00009534737],"about_ca_topic_score_codex":0.0000012417797,"about_ca_topic_score_gemma":9.646535e-8,"teacher_disagreement_score":0.0017727896,"about_ca_system_score_codex":0.00002677258,"about_ca_system_score_gemma":0.00003837372,"threshold_uncertainty_score":0.23722802},"labels":[],"label_agreement":null},{"id":"W2301781406","doi":"10.1096/fasebj.22.1_supplement.645.9","title":"RGS13 restricts G‐protein‐coupled receptor‐induced responses in mast cells","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Degranulation; Cell biology; G protein-coupled receptor; Heterotrimeric G protein; G protein; Mast cell; Signal transduction; Chemotaxis; Interleukin 33; Gi alpha subunit; Chemistry; Cytokine; Biology; Receptor; Immunology; Interleukin; Biochemistry","score_opus":0.02437557689260692,"score_gpt":0.23711900906253142,"score_spread":0.2127434321699245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2301781406","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979101,0.00044274083,0.00062816613,0.00024342301,0.0003473932,0.00016331018,0.000004417701,0.000007771677,0.000252688],"genre_scores_gemma":[0.99597806,0.00048126388,0.0008838285,0.00014889837,0.0005364981,0.000008535562,0.0000068069094,0.000025415246,0.001930684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99862695,0.00027626517,0.0003083516,0.00020819214,0.00023713785,0.00034310215],"domain_scores_gemma":[0.9993468,0.00002816307,0.00015115552,0.00027831204,0.0000747715,0.0001207852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070922106,0.0001639056,0.00015794385,0.00008536451,0.00031721464,0.000041878775,0.0003324849,0.00014178682,0.0002740455],"category_scores_gemma":[0.00012177423,0.00011663231,0.000116305004,0.00015468267,0.000054362747,0.0000070155993,0.00007235755,0.00036630285,0.000040852898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031698472,0.000035459976,0.0001624463,0.0000020800946,0.000019665698,0.000049539056,0.000140284,0.00009861971,0.99806017,0.000018647528,0.0007695878,0.00032651666],"study_design_scores_gemma":[0.0006626556,0.00030303112,0.00028307654,0.000029559222,0.00000579256,0.00025579627,0.00020422088,0.00006491667,0.9958868,0.00008252824,0.0020606783,0.00016093004],"about_ca_topic_score_codex":0.000030030154,"about_ca_topic_score_gemma":0.00000913805,"teacher_disagreement_score":0.002173354,"about_ca_system_score_codex":0.000030871033,"about_ca_system_score_gemma":0.00018129837,"threshold_uncertainty_score":0.47561276},"labels":[],"label_agreement":null},{"id":"W2302210535","doi":"10.7554/elife.12052","title":"Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine","year":2016,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Howard Hughes Medical Institute; National Institute on Drug Abuse; U.S. Public Health Service; Wellcome Trust; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Ventral tegmental area; Long-term potentiation; Addiction; Neuroscience; Metabotropic glutamate receptor; Dopaminergic; Synaptic plasticity; Glutamate receptor; Pharmacology; Psychology; Dopamine; Biology; Medicine; Internal medicine; Receptor","score_opus":0.00498127789660239,"score_gpt":0.23592212326439316,"score_spread":0.23094084536779078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2302210535","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97265077,0.00086110417,0.025533982,0.0006265481,0.0000721339,0.00021783815,0.000026735997,0.0000041800736,0.0000067319506],"genre_scores_gemma":[0.99942905,0.00002807258,0.0002396731,0.00012406675,0.000059282935,0.000019263556,0.0000147612045,0.0000069149987,0.00007894643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994808,0.000052835778,0.00012377331,0.00015174311,0.000101868565,0.00008901222],"domain_scores_gemma":[0.9996912,0.00005158928,0.00003730834,0.00012168962,0.000055908025,0.000042307947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020729608,0.00006894948,0.00008804929,0.000008567255,0.00004539438,0.0000058611417,0.000054794888,0.00005943587,0.000025989275],"category_scores_gemma":[0.00006483832,0.000040216855,0.00003400377,0.000024041105,0.00003956723,0.0000025636837,0.000011932493,0.000022303986,0.0000016193624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006309334,0.000023001374,0.0014132988,0.00000656104,0.000018800185,1.03279895e-7,0.000035063553,0.000019969348,0.99309176,0.00008943201,0.00040453742,0.0048343716],"study_design_scores_gemma":[0.0006161855,0.00028694439,0.004594609,0.000014886244,0.000018793582,0.0000010179419,0.000006169839,0.00007040009,0.9924436,0.000061500185,0.0018194513,0.000066438246],"about_ca_topic_score_codex":0.000011223524,"about_ca_topic_score_gemma":0.0000061135834,"teacher_disagreement_score":0.026778271,"about_ca_system_score_codex":0.000003841598,"about_ca_system_score_gemma":0.000013318156,"threshold_uncertainty_score":0.16399959},"labels":[],"label_agreement":null},{"id":"W2302828574","doi":"10.1038/nature17154","title":"The conformational signature of β-arrestin2 predicts its trafficking and signalling functions","year":2016,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":224,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Institute for Health and Care Research; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"G protein-coupled receptor; Arrestin; Chemistry; Receptor; Effector; Biophysics; Cell biology; Signal transduction; G protein; Biochemistry; Biology","score_opus":0.0059266114928739014,"score_gpt":0.2201946787492995,"score_spread":0.21426806725642558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2302828574","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9786971,0.010626857,0.00798212,0.0007575481,0.00057231594,0.00020565785,0.00007040693,0.000020349398,0.0010676066],"genre_scores_gemma":[0.9986455,0.00024071423,0.00017755605,0.00011366415,0.00022643675,0.000005654815,0.000022579141,0.000008325436,0.0005596126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944437,0.000022804443,0.00013329678,0.0001323647,0.00014210712,0.00012504343],"domain_scores_gemma":[0.99958986,0.000062213796,0.00007788645,0.00009172783,0.00013765406,0.00004063111],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018594025,0.000083088176,0.0000667543,0.000018156275,0.0001505587,0.000017098453,0.00010192124,0.000538244,0.000031800948],"category_scores_gemma":[0.00015352007,0.00004493842,0.00004320698,0.000043949225,0.00004252319,0.000006434496,0.000034611556,0.00029148205,0.0000015391018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004130673,0.0000063450943,0.00008513994,0.000009384496,0.000030869433,2.9063585e-7,0.000029113537,0.00007659019,0.99059474,0.0018693759,0.0015538424,0.00570299],"study_design_scores_gemma":[0.00061522354,0.00016501015,0.00067693955,0.00009474526,0.000021272472,0.000016009888,0.00012586937,0.00036707483,0.9087214,0.00026109643,0.08877592,0.0001594285],"about_ca_topic_score_codex":2.6148678e-7,"about_ca_topic_score_gemma":0.0000021618755,"teacher_disagreement_score":0.08722208,"about_ca_system_score_codex":0.0000041840417,"about_ca_system_score_gemma":0.00004114841,"threshold_uncertainty_score":0.41514307},"labels":[],"label_agreement":null},{"id":"W2304807111","doi":"10.1523/jneurosci.4124-15.2016","title":"Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor Function","year":2016,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Drug Abuse; University of Illinois at Urbana-Champaign; National Institutes of Health; Agence Nationale de la Recherche; European Commission","keywords":"Arrestin; Agonist; Functional selectivity; δ-opioid receptor; Receptor; G protein-coupled receptor; Cell biology; Opioid receptor; μ-opioid receptor; Chemistry; Opioid; Pharmacology; Biology; Neuroscience; Signal transduction; Internal medicine; Biochemistry; Medicine","score_opus":0.044075583532768144,"score_gpt":0.26714145210444945,"score_spread":0.22306586857168131,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2304807111","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9066868,0.00022439995,0.09137233,0.00012765492,0.001428642,0.00010265614,0.000008216858,0.000003005692,0.000046304573],"genre_scores_gemma":[0.9973978,0.00096200005,0.00096249185,0.00009718662,0.00027257446,0.0000032444389,0.0000014937137,0.000011054766,0.00029215706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988269,0.00004910875,0.00040951304,0.00020815118,0.00031704668,0.0001892309],"domain_scores_gemma":[0.9990851,0.000016302642,0.0004316911,0.0001868491,0.00017272448,0.000107278975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029996622,0.00011369027,0.00016079374,0.00006709359,0.00007503453,0.0000276157,0.00031000708,0.000066637076,0.000047902522],"category_scores_gemma":[0.00012063032,0.00006788443,0.00013155949,0.000095957126,0.00009731618,0.000017652737,0.000067286725,0.00007621636,0.0000025040677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001594179,0.000060059254,0.00023415852,0.0000050759263,0.0000044443186,0.0000019710226,0.000013113885,0.000026238096,0.9840361,0.00016065524,0.00051838736,0.014780413],"study_design_scores_gemma":[0.0004731205,0.0015574893,0.0031211975,0.000057208636,0.000008898306,0.000033903834,0.000017011487,0.000024530333,0.95177037,0.00027078344,0.04256154,0.00010397297],"about_ca_topic_score_codex":0.0000010547701,"about_ca_topic_score_gemma":6.228205e-7,"teacher_disagreement_score":0.090711005,"about_ca_system_score_codex":0.000018332566,"about_ca_system_score_gemma":0.00008751503,"threshold_uncertainty_score":0.27682465},"labels":[],"label_agreement":null},{"id":"W2312315246","doi":"10.1021/jm4014828","title":"Discovery of Spirofused Piperazine and Diazepane Amides as Selective Histamine-3 Antagonists with in Vivo Efficacy in a Mouse Model of Cognition","year":2014,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"OmegaChem (Canada); AstraZeneca (Canada)","funders":"","keywords":"Chemistry; In vivo; Pharmacology; Histamine H3 receptor; Carboxamide; Histamine; Piperazine; Structure–activity relationship; Receptor; Antagonist; In vitro; Stereochemistry; Biochemistry","score_opus":0.006249343149582207,"score_gpt":0.22878152928207945,"score_spread":0.22253218613249726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2312315246","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99741626,0.00033787478,0.0019232268,0.0000380116,0.000013511946,0.000053859025,0.0000092344635,9.243825e-7,0.00020709037],"genre_scores_gemma":[0.99889857,0.00022987887,0.0006157938,0.000027099413,0.000085662345,0.000001589983,0.0000075393505,0.00001193937,0.00012190873],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990565,0.000029441402,0.0004287657,0.00014101494,0.00022053158,0.0001237291],"domain_scores_gemma":[0.9993092,0.000036424215,0.00036529888,0.00009041868,0.00014148072,0.000057169807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003237756,0.00012300265,0.0003376418,0.00005774602,0.000012270958,0.0000054525312,0.00008970817,0.00010552361,0.0000071693817],"category_scores_gemma":[0.00020338198,0.000095907286,0.000047382426,0.000073645635,0.00010141859,0.00001139858,0.000022073316,0.00016607801,2.883856e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000985388,0.00018663467,0.0011244566,0.00015281921,0.000032821496,0.000007918247,0.00017253695,0.000554501,0.9964886,0.000005943719,0.000012400639,0.00027598304],"study_design_scores_gemma":[0.0027888499,0.00076675985,0.00029019653,0.0003262527,0.00003567222,0.00007371228,0.00027979308,0.00079114496,0.99446315,0.000077160475,0.000010759809,0.00009652743],"about_ca_topic_score_codex":0.000027448566,"about_ca_topic_score_gemma":0.000014623789,"teacher_disagreement_score":0.0020254257,"about_ca_system_score_codex":0.000024231922,"about_ca_system_score_gemma":0.000119566444,"threshold_uncertainty_score":0.39109856},"labels":[],"label_agreement":null},{"id":"W2312328575","doi":"10.1385/cbb:46:1:1","title":"Arrestin Interaction With Rhodopsin: Conceptual Models","year":2006,"lang":"en","type":"article","venue":"Cell Biochemistry and Biophysics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Rhodopsin; G protein-coupled receptor; Arrestin; Function (biology); Receptor; Biology; Visual phototransduction; Computational biology; Signal transduction; Cell biology; Chemistry; Biophysics; Neuroscience; Biochemistry; Retina; Retinal","score_opus":0.007900727463462189,"score_gpt":0.1929223938398357,"score_spread":0.18502166637637352,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2312328575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98824537,0.00039042087,0.0068435194,0.000021449956,0.000067153,0.00006728966,0.000014789646,0.000017006376,0.0043329876],"genre_scores_gemma":[0.99653244,0.000044618257,0.0014606067,0.000057889807,0.00048040124,0.00000807781,0.00024787092,0.000018099056,0.0011500102],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923986,0.000012956353,0.00013158715,0.0003439266,0.000091880815,0.0001798079],"domain_scores_gemma":[0.9996164,0.0000068995782,0.00008012903,0.00018051958,0.000056533212,0.00005953945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004403321,0.00017507449,0.0001149699,0.00000967325,0.00008901408,0.000039472503,0.0000738984,0.00012936,0.000016318327],"category_scores_gemma":[0.000002647097,0.0001491393,0.000046228237,0.000056668134,0.0001269465,0.0000073627507,0.000044661843,0.00008914992,0.0000028961351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000069591406,0.000056681172,0.000057928813,0.00002530628,0.000009332899,0.0000027424496,0.000015601318,0.00041870325,0.99836046,0.00020721076,0.00038760595,0.000388828],"study_design_scores_gemma":[0.00035908967,0.00013154438,0.000009873275,0.000019120274,0.000015908356,0.0000133480535,0.00021008756,0.00043724888,0.9966293,0.00038006794,0.0015653459,0.00022906276],"about_ca_topic_score_codex":0.000021381516,"about_ca_topic_score_gemma":0.0000012997994,"teacher_disagreement_score":0.008287042,"about_ca_system_score_codex":0.0000078877465,"about_ca_system_score_gemma":0.000033953373,"threshold_uncertainty_score":0.6081724},"labels":[],"label_agreement":null},{"id":"W2314578671","doi":"10.1139/v11-076","title":"Theoretical investigation of the conformational intricacies and thermodynamic functions of noradrenaline","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Catechol; Conformational isomerism; Protonation; Hydrogen bond; Intramolecular force; Ring (chemistry); Docking (animal); Computational chemistry; Stereochemistry; Molecule; Organic chemistry","score_opus":0.0077822585777236305,"score_gpt":0.17359476120582268,"score_spread":0.16581250262809905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2314578671","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978748,0.0002716648,0.00051784806,0.00005992244,0.000052389638,0.000020962227,0.000022182603,3.1119112e-7,0.0011799155],"genre_scores_gemma":[0.9996685,0.00001286774,0.00020020828,0.000028916098,0.000047247642,4.0659575e-7,0.000006890855,0.000003542325,0.000031412143],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99960756,0.000014468955,0.00021120667,0.000039358692,0.000065025146,0.0000624001],"domain_scores_gemma":[0.9994566,0.000006970592,0.00018897117,0.00007783349,0.0001678452,0.00010181983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013054884,0.00004701929,0.000077676195,0.000019315357,0.000032438318,0.0000039995857,0.0001053909,0.00006306688,0.0003499739],"category_scores_gemma":[0.0000742943,0.00003355285,0.000051931434,0.000044366472,0.00028343464,0.000004025163,0.000010654083,0.000066047236,9.549309e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000122168585,0.0000031896416,0.0023571881,0.000020050382,0.000030391666,4.2395962e-7,0.00023420634,0.00000973747,0.9956942,0.0013506478,0.00006624192,0.00022148962],"study_design_scores_gemma":[0.00015355612,0.00004203849,0.0029012011,0.00003333958,0.000016790447,0.000062941835,0.00026911282,0.00006577367,0.99407065,0.0022462932,0.00009793131,0.000040358893],"about_ca_topic_score_codex":0.000050672603,"about_ca_topic_score_gemma":0.000038551592,"teacher_disagreement_score":0.0017937047,"about_ca_system_score_codex":0.0000075650405,"about_ca_system_score_gemma":0.0003665635,"threshold_uncertainty_score":0.3831969},"labels":[],"label_agreement":null},{"id":"W2314877083","doi":"10.1177/2045125316637570","title":"Multiple D2 heteroreceptor complexes: new targets for treatment of schizophrenia","year":2016,"lang":"en","type":"review","venue":"Therapeutic Advances in Psychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Dopamine receptor D2; Neuroscience; Metabotropic glutamate receptor 5; G protein-coupled receptor; Agonist; Chemistry; Metabotropic receptor; Metabotropic glutamate receptor; Dopamine; Biology; Receptor; Signal transduction; Cell biology; Biochemistry","score_opus":0.041021159629292606,"score_gpt":0.3933467705085898,"score_spread":0.3523256108792972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2314877083","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011007989,0.9847239,0.011197563,0.000021084574,0.0020059093,0.0016809109,0.0001966561,0.0000147134515,0.00004914863],"genre_scores_gemma":[0.00033558934,0.99346364,0.0035276234,0.00006421718,0.0012913627,0.0005636924,0.00021835603,0.00009843458,0.00043707655],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99771625,0.00019388483,0.0007913175,0.0007192668,0.00009789521,0.00048137046],"domain_scores_gemma":[0.9987525,0.00019549212,0.00051533367,0.0003677238,0.000052501087,0.00011646239],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011361086,0.0005620397,0.0015424829,0.00015998521,0.000050326587,0.0000068001987,0.0004185033,0.00042253637,0.0003840865],"category_scores_gemma":[0.000012507118,0.0004018359,0.00058957306,0.00011349592,0.00012158806,0.000008149078,0.00003917472,0.00007547047,0.000016210077],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009052296,0.00014885224,0.0000015107006,0.0008238025,0.00032525847,9.880755e-7,0.000033640594,0.00001050114,0.036756843,0.0000657587,0.00015287794,0.9607747],"study_design_scores_gemma":[0.0050564692,0.0013752339,1.790734e-7,0.00065667776,0.00020377767,0.000008252339,0.000009700092,0.000008111274,0.00909355,0.00071043987,0.9824783,0.00039928252],"about_ca_topic_score_codex":0.000004129171,"about_ca_topic_score_gemma":0.000009633568,"teacher_disagreement_score":0.98232543,"about_ca_system_score_codex":0.000080611724,"about_ca_system_score_gemma":0.00020770042,"threshold_uncertainty_score":0.99984336},"labels":[],"label_agreement":null},{"id":"W2319314090","doi":"10.1515/hsz-2011-0284","title":"Rab1 interacts directly with the β2-adrenergic receptor to regulate receptor anterograde trafficking","year":2012,"lang":"en","type":"article","venue":"Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"GTPase; Rab; Cell biology; G protein-coupled receptor; Endocytic cycle; Endoplasmic reticulum; Receptor; GTP-binding protein regulators; Small GTPase; G protein; Chemistry; Biology; Signal transduction; Biochemistry; Endocytosis","score_opus":0.015782120908250315,"score_gpt":0.23545686650113615,"score_spread":0.21967474559288583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2319314090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99642575,0.0009595223,0.00063889124,0.0004495299,0.00024518883,0.00019903823,0.000018714045,0.00006280749,0.0010005578],"genre_scores_gemma":[0.99495775,0.00010616289,0.0017254688,0.0005725231,0.0012380527,0.00007149585,0.00019341924,0.00003567427,0.0010994552],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99831766,0.00009062659,0.00025674084,0.00051485526,0.00017224428,0.000647872],"domain_scores_gemma":[0.99903595,0.000040277646,0.00012361779,0.0004171581,0.00007315471,0.00030981534],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037347875,0.00033269764,0.00025898407,0.000015385225,0.00017284651,0.00006496513,0.00043858,0.0003153334,0.00064392237],"category_scores_gemma":[0.00012260114,0.00018981025,0.00015557373,0.00016175324,0.00011679759,0.000008953057,0.00018852028,0.00021791695,0.000049278267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002254218,0.0000872489,0.00054522353,0.000011281205,0.00005388157,0.0000010850879,0.000093555405,0.00002878461,0.99362093,0.000019547433,0.0028536138,0.0024594474],"study_design_scores_gemma":[0.00023317871,0.0002201414,0.00028208861,0.000037123944,0.000011104508,0.000023272492,0.00017702662,0.0000048549437,0.85957974,0.000003035917,0.13911872,0.0003097073],"about_ca_topic_score_codex":0.0000046823807,"about_ca_topic_score_gemma":0.0000013545937,"teacher_disagreement_score":0.13626511,"about_ca_system_score_codex":0.000030018175,"about_ca_system_score_gemma":0.000025811905,"threshold_uncertainty_score":0.7740238},"labels":[],"label_agreement":null},{"id":"W2321503397","doi":"10.1124/mol.60.5.999","title":"Allosteric Effects of G Protein Overexpression on the Binding of β-Adrenergic Ligands with Distinct Inverse Efficacies","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Medical Research Council Canada; Heart and Stroke Foundation of Canada","keywords":"Allosteric regulation; Adenylyl cyclase; G protein; Inverse agonist; Receptor; Intrinsic activity; BETA (programming language); Chemistry; Biochemistry; Sf9; Allosteric modulator; Recombinant DNA; Biology; Antagonist; Agonist; Gene; Spodoptera","score_opus":0.006966070283914955,"score_gpt":0.2332503037194656,"score_spread":0.22628423343555062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2321503397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997934,0.00015037999,0.0010673505,0.00006518641,0.00006942346,0.00040314737,0.000010964761,0.0000073527012,0.00029218587],"genre_scores_gemma":[0.99920577,0.000034324217,0.0002045186,0.00018443176,0.000050781768,0.000078527366,0.000040156236,0.000023738154,0.0001777292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907696,0.00013041604,0.00018525256,0.00024670383,0.0001542634,0.00020641851],"domain_scores_gemma":[0.99946034,0.000047223846,0.00017673308,0.00020774886,0.000056821413,0.000051151972],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117922085,0.00016685862,0.00019459552,0.000053920725,0.000057015364,0.0000055083706,0.00020477083,0.0001049532,0.00032635583],"category_scores_gemma":[0.000044078603,0.000108219436,0.00008902621,0.00014031076,0.00011394801,0.0000024595265,0.000098262986,0.00009767006,0.0000028228358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040844316,0.00011274183,0.000062622436,0.000059613827,0.00009870149,0.000032947246,0.000035339446,0.00029995712,0.9981347,0.00010372474,0.00036492574,0.0002862927],"study_design_scores_gemma":[0.00089851086,0.0012128877,0.00005968965,0.00013741806,0.000039620438,0.000011809035,0.000022160822,0.00010999246,0.9958904,0.000019731175,0.0014720283,0.00012576696],"about_ca_topic_score_codex":0.0000062585905,"about_ca_topic_score_gemma":0.0000010859504,"teacher_disagreement_score":0.0022443058,"about_ca_system_score_codex":0.000008372244,"about_ca_system_score_gemma":0.000036062473,"threshold_uncertainty_score":0.44130605},"labels":[],"label_agreement":null},{"id":"W2322796880","doi":"10.1038/nature17629","title":"X-ray structures and mechanism of the human serotonin transporter","year":2016,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":700,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute of Mental Health; Howard Hughes Medical Institute","keywords":"Allosteric regulation; Citalopram; Chemistry; Serotonergic; Reuptake; Antidepressant; Reuptake inhibitor; Serotonin Plasma Membrane Transport Proteins; Neurotransmitter; Neurotransmitter transporter; Serotonin transporter; Biophysics; Serotonin; Pharmacology; Neuroscience; Biology; Biochemistry; Receptor; Hippocampus","score_opus":0.004603576970692066,"score_gpt":0.22575949924554234,"score_spread":0.2211559222748503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2322796880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982086,0.00039966547,0.0007557052,0.00021246479,0.0001338105,0.00010191145,0.000018560277,0.000003506128,0.00016576852],"genre_scores_gemma":[0.99886435,0.00002861412,0.0002943547,0.00024029496,0.0000825402,0.0000032886612,0.00000416557,0.000009263893,0.00047313666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995804,0.00001911197,0.00008032381,0.00014769526,0.00008578062,0.00008672766],"domain_scores_gemma":[0.9997326,0.0000029607595,0.000042106123,0.0001692346,0.000029877796,0.00002321159],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006340072,0.00007481309,0.00007106138,0.000010003361,0.00004796158,0.0000044135313,0.00012201256,0.0005119356,0.00008899184],"category_scores_gemma":[0.000008109865,0.000036135916,0.00005273206,0.000021575084,0.000033115226,0.0000015363609,0.000026805174,0.00017437637,2.1697466e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000069046932,0.0000036290442,0.00041619927,0.000006304324,0.000014217179,2.5800202e-7,0.000023945744,5.2152234e-7,0.9878872,0.010843679,0.00015395219,0.0006432099],"study_design_scores_gemma":[0.0002484717,0.000049326543,0.0033975039,0.000016161948,0.000008482722,0.0000026076086,0.000013392831,5.90839e-7,0.986493,0.0050139283,0.0046935068,0.00006304295],"about_ca_topic_score_codex":0.0000020227076,"about_ca_topic_score_gemma":0.0000065479217,"teacher_disagreement_score":0.0058297515,"about_ca_system_score_codex":0.0000021094788,"about_ca_system_score_gemma":0.0000104698465,"threshold_uncertainty_score":0.39485162},"labels":[],"label_agreement":null},{"id":"W2323486484","doi":"10.1139/y11-117","title":"Bronchial inflammation induced PKC<sub>ζ</sub> over-expression: involvement in mechanical properties of airway smooth muscle","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université du Québec; Université de Sherbrooke","funders":"","keywords":"Inflammation; Airway; Smooth muscle; Protein kinase C; Medicine; Immunology; Internal medicine; Cell biology; Endocrinology; Biology; Signal transduction; Anesthesia","score_opus":0.017058912962196984,"score_gpt":0.23953721697503644,"score_spread":0.22247830401283947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2323486484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997886,0.0010462662,0.000040879226,0.00009375677,0.00080135034,0.00011269205,0.0000044138947,0.0000010652418,0.000013602981],"genre_scores_gemma":[0.9988286,0.00015170264,0.000056807337,0.00021794433,0.00071768375,0.000007289498,0.0000074786803,0.000009987309,0.000002496557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989677,0.0002046786,0.00035105823,0.00012453906,0.000057223668,0.0002948094],"domain_scores_gemma":[0.99936736,0.0000134867405,0.00021824581,0.0000687378,0.00007763026,0.00025453995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035733555,0.00011840383,0.000234788,0.00012437406,0.000063609186,0.0000038417816,0.0001206262,0.00021745464,0.00021361466],"category_scores_gemma":[0.000026128282,0.00010138365,0.00006350031,0.000055624416,0.00008511759,0.000019244002,0.000034577435,0.0002053415,7.545808e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012587602,0.000031701722,0.00031982755,0.000038644674,0.000035037607,0.0000025756049,0.0003048859,0.000053506938,0.9974724,0.00006829852,0.00019959958,0.001347611],"study_design_scores_gemma":[0.0008226237,0.00039937292,0.002825051,0.000030105406,0.000021978223,0.000007727396,0.00009147961,0.000023365972,0.99431455,0.00013064119,0.0012282043,0.00010490468],"about_ca_topic_score_codex":0.00013393856,"about_ca_topic_score_gemma":0.00048177544,"teacher_disagreement_score":0.0031578895,"about_ca_system_score_codex":0.000030381874,"about_ca_system_score_gemma":0.00031063546,"threshold_uncertainty_score":0.4134305},"labels":[],"label_agreement":null},{"id":"W2324795415","doi":"10.1139/bcb-2013-0042","title":"M<sub>3</sub> muscarinic acetylcholine receptor dysfunction inhibits Rac1 activity and disrupts VE-cadherin/β-catenin and actin cytoskeleton interaction","year":2014,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Adherens junction; Cell biology; IQGAP1; Actin cytoskeleton; Biology; Cytoskeleton; Muscarinic acetylcholine receptor; RAC1; Cadherin; Chemistry; Receptor; Biochemistry; Signal transduction; Scaffold protein","score_opus":0.006971512512758858,"score_gpt":0.22330747730747974,"score_spread":0.2163359647947209,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2324795415","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973139,0.0007648789,0.0009836416,0.00010070005,0.00028387137,0.00013655865,0.000018214505,0.000025376923,0.00037284536],"genre_scores_gemma":[0.99701077,0.0017634234,0.00018889004,0.00009320026,0.00045974262,0.000024430701,0.00022113752,0.00002574149,0.00021264203],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99856484,0.00011605945,0.00022692123,0.0007290134,0.000060648108,0.00030252183],"domain_scores_gemma":[0.99934447,0.00004266662,0.00017291761,0.00021829705,0.000051513725,0.00017015962],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028961888,0.00029455672,0.0002599018,0.000035048633,0.00016365616,0.000043694712,0.00007789527,0.0005253797,0.000024406596],"category_scores_gemma":[0.0000845964,0.0002790339,0.000060526803,0.000059370013,0.00015002342,0.000014700473,0.00018914626,0.00023950804,0.000004965186],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002728151,0.000048547812,0.00039507335,0.00008068899,0.000027241838,3.1440945e-7,0.000029658906,0.0000015782853,0.94627583,0.000010668366,0.00010315227,0.052754443],"study_design_scores_gemma":[0.00083398377,0.0004366983,0.00030870218,0.000023583701,0.0000285278,0.000032654654,0.00009461176,0.00012553086,0.98978627,0.000033140324,0.007980736,0.0003155537],"about_ca_topic_score_codex":0.000018781835,"about_ca_topic_score_gemma":0.000007204398,"teacher_disagreement_score":0.05243889,"about_ca_system_score_codex":0.000016574058,"about_ca_system_score_gemma":0.000025092617,"threshold_uncertainty_score":0.9999662},"labels":[],"label_agreement":null},{"id":"W2325085017","doi":"10.1016/j.cjca.2011.07.219","title":"291 Angiotensin II induces diastolic dysfunction via the AT1 receptor with a reduction in carbohydrate oxidation caused by up-regulation of pyruvate dehydrogenase kinase 4 (PDK4)","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton","funders":"","keywords":"Internal medicine; Endocrinology; Medicine; Angiotensin II; Heart failure; Angiotensin II receptor type 1; Pyruvate dehydrogenase complex; Irbesartan; Pyruvate dehydrogenase kinase; PDK4; Muscle hypertrophy; Cardiac function curve; Receptor; Chemistry; Blood pressure; Biochemistry","score_opus":0.012147073475433092,"score_gpt":0.19009210372031152,"score_spread":0.17794503024487843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2325085017","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942215,0.0004959848,0.004354425,0.00012792832,0.0005759824,0.00014444826,0.000013164136,0.0000019334539,0.00006465165],"genre_scores_gemma":[0.9992957,0.000053228177,0.00015098328,0.000032622815,0.0003418629,0.000006164691,0.000068113266,0.000018467492,0.000032816242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893355,0.00021677604,0.00035710944,0.00017277236,0.000092572925,0.00022718801],"domain_scores_gemma":[0.9990749,0.0000069938574,0.00034085213,0.00017609545,0.00024827354,0.00015292063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042752715,0.00013618034,0.0002506,0.00018854103,0.00010801292,0.000008181218,0.00012251904,0.00019356153,0.000024477678],"category_scores_gemma":[0.000044053235,0.000103590864,0.00009826257,0.00018586167,0.00012375743,0.000018392679,0.000010991039,0.00014660943,8.623165e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017050003,0.0000037012094,0.00055529096,0.0000029585697,0.00010881369,0.0000034557572,0.00040555125,0.0013440207,0.99492913,0.000023467115,0.00079289125,0.0016602317],"study_design_scores_gemma":[0.00059082196,0.0008494576,0.0026464798,0.000025045785,0.00006159351,0.00008744266,0.00024616736,0.00004323545,0.99174106,0.00011811512,0.003452974,0.00013758751],"about_ca_topic_score_codex":0.0020305302,"about_ca_topic_score_gemma":0.0018076096,"teacher_disagreement_score":0.005074259,"about_ca_system_score_codex":0.00006855462,"about_ca_system_score_gemma":0.00033184877,"threshold_uncertainty_score":0.4224313},"labels":[],"label_agreement":null},{"id":"W2325324774","doi":"10.1515/tnsci-2016-0004","title":"Teneurins, TCAP, and latrophilins: roles in the etiology of mood disorders","year":2016,"lang":"en","type":"review","venue":"Translational Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neuroscience; Mood disorders; Startle response; Hippocampal formation; Behavioural despair test; Biology; Psychology; Anxiety; Psychiatry; Hippocampus","score_opus":0.022510708648861847,"score_gpt":0.29715202556292897,"score_spread":0.2746413169140671,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2325324774","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001916195,0.9959428,0.0011777139,0.00017831638,0.00013048765,0.00034234056,0.00007892082,0.0000033401184,0.00022989459],"genre_scores_gemma":[0.048732355,0.9510089,0.000086240594,0.00004191482,0.000055789304,0.000021860336,0.000021612086,0.00001082087,0.000020516514],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99892414,0.00015717912,0.0002744042,0.00035267082,0.00014634966,0.00014526876],"domain_scores_gemma":[0.99962866,0.00006188149,0.00010538789,0.00016712185,0.000013782622,0.000023170342],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023086158,0.00015316943,0.00027554206,0.00006226596,0.000048543592,0.000010244344,0.00030883,0.00012664974,0.000007303845],"category_scores_gemma":[0.00003782744,0.000089565256,0.000117556476,0.00011681454,0.0001903876,0.000004270461,0.000027326601,0.00009756015,7.9125965e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000254714,0.00015378594,0.00041791282,0.0015511494,0.000019426765,0.0000017448671,0.000117113916,0.00012392213,0.08300836,0.00829407,0.000023009472,0.906264],"study_design_scores_gemma":[0.00046539106,0.00042079564,0.001363533,0.00103707,0.00006449361,0.000068944784,0.000012440859,0.000047491154,0.0005286599,0.002377325,0.9931774,0.00043643903],"about_ca_topic_score_codex":0.0000020075734,"about_ca_topic_score_gemma":0.00002776332,"teacher_disagreement_score":0.9931544,"about_ca_system_score_codex":0.0000015956253,"about_ca_system_score_gemma":0.00008244062,"threshold_uncertainty_score":0.36523652},"labels":[],"label_agreement":null},{"id":"W2330532211","doi":"10.1139/y2012-006","title":"Autoantibodies against cardiac β<sub>1</sub>-adrenoceptor do not affect the low-affinity state β<sub>1</sub>-adrenoceptor-mediated inotropy in rat cardiomyocytes","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Inotrope; Internal medicine; Endocrinology; Agonist; Pindolol; Receptor; Chemistry; Extracellular; Propranolol; Antagonist; Biology; Medicine; Biochemistry","score_opus":0.008524571441567432,"score_gpt":0.23366816053714096,"score_spread":0.22514358909557353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2330532211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9880766,0.007594542,0.000038047845,0.00022468921,0.0035738447,0.00031353667,0.00013383545,0.000008486213,0.000036381418],"genre_scores_gemma":[0.99334466,0.0036323473,0.00003621326,0.0012094247,0.0016083517,0.000024853163,0.00008873302,0.000046995043,0.0000084228395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968831,0.0009331038,0.000600337,0.00039151384,0.00014329863,0.0010486811],"domain_scores_gemma":[0.9982139,0.00023203697,0.0003986016,0.00022658474,0.00022224612,0.0007066364],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010494569,0.00043081137,0.00074762624,0.00026473313,0.00035941746,0.000038435795,0.00039094477,0.00040355985,0.00019460687],"category_scores_gemma":[0.0001285298,0.00034631888,0.00031164903,0.00020995733,0.00052548887,0.00004233649,0.0000969396,0.00076418376,0.00002162612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028280867,0.000042203566,0.0035211868,0.000055126526,0.00040147436,0.000031731543,0.0005235096,0.00028380012,0.98814434,0.000018831914,0.0042882264,0.0024067585],"study_design_scores_gemma":[0.001120708,0.00036568395,0.007821589,0.000028635766,0.00010917738,0.000048357742,0.00015382394,0.000021301987,0.9844395,0.00007123393,0.005444508,0.0003754868],"about_ca_topic_score_codex":0.00011699164,"about_ca_topic_score_gemma":0.00041921833,"teacher_disagreement_score":0.0052680224,"about_ca_system_score_codex":0.000113195754,"about_ca_system_score_gemma":0.0008293042,"threshold_uncertainty_score":0.9998989},"labels":[],"label_agreement":null},{"id":"W2333488286","doi":"10.1124/mol.114.093476","title":"Role of SAP97 in the Regulation of 5-HT2AR Endocytosis and Signaling","year":2014,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"PDZ domain; HEK 293 cells; Gene knockdown; Cell biology; Internalization; Biology; Ankyrin repeat; Receptor; Biochemistry; Gene","score_opus":0.005161136667635055,"score_gpt":0.2408256091475777,"score_spread":0.23566447247994265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2333488286","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99499434,0.0007497527,0.0036180064,0.00006651535,0.00004404458,0.00013988669,0.0000022180905,0.0000020930793,0.0003831282],"genre_scores_gemma":[0.9988731,0.00004911763,0.00074216374,0.00024225716,0.000049497212,0.000014111586,0.000013430415,0.00000957283,0.0000067350875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991723,0.00023792872,0.00020805272,0.00016744786,0.00008817424,0.00012615218],"domain_scores_gemma":[0.99968433,0.000029979961,0.00010359668,0.0001203654,0.00004007406,0.000021679605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040198088,0.0000831291,0.00014238982,0.00005082126,0.00002151659,0.0000034747197,0.00013022199,0.00008286663,0.000056124078],"category_scores_gemma":[0.000026905624,0.00006958354,0.000050596485,0.00007488651,0.000059850743,0.000002125532,0.000047960497,0.00005913646,4.3294156e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004227035,0.000032785745,0.0003304705,0.000015964026,0.000024009263,4.949804e-7,0.00011693459,0.00063616893,0.9957641,0.00086343253,0.000028356071,0.0021450354],"study_design_scores_gemma":[0.0005066028,0.00020500374,0.0005681338,0.0000060890006,0.000028442513,0.0000061733153,0.00008666067,0.00089895795,0.9951268,0.0008360824,0.0016646588,0.000066411885],"about_ca_topic_score_codex":0.000017276256,"about_ca_topic_score_gemma":0.0000024480098,"teacher_disagreement_score":0.0038787595,"about_ca_system_score_codex":0.0000032700623,"about_ca_system_score_gemma":0.000014319183,"threshold_uncertainty_score":0.28375345},"labels":[],"label_agreement":null},{"id":"W2334275131","doi":"10.1073/pnas.1521706113","title":"Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction","year":2016,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"Medical Research Council; National Institutes of Health; European Regional Development Fund; Deutsche Forschungsgemeinschaft; National Institute for Health and Care Research; Canadian Institutes of Health Research; European Commission","keywords":"Phosphorylation; Cell biology; Signal transduction; Receptor; Contraction (grammar); G protein-coupled receptor; Biology; Chemistry; Endocrinology; Biochemistry","score_opus":0.03277205157753081,"score_gpt":0.26815478690641514,"score_spread":0.23538273532888432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2334275131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99845225,0.00011882834,0.00020658528,0.0005522331,0.000026661686,0.00050363026,0.00001903129,0.000005748746,0.00011503645],"genre_scores_gemma":[0.99474967,0.00003339052,0.0047790334,0.00007061037,0.00016663027,0.00009008668,0.0000011178387,0.0000058991664,0.00010358438],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987559,0.000012578104,0.00036555447,0.00030763538,0.00038413875,0.00017423539],"domain_scores_gemma":[0.9991911,0.000054716955,0.00045037654,0.00000973987,0.00026721848,0.000026831485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015315975,0.00010149136,0.00015605481,0.00007773282,0.00012649222,0.000013002264,0.0003210896,0.00015832318,0.0000315395],"category_scores_gemma":[0.0008273568,0.000060134782,0.00009986899,0.00023649709,0.00016997021,0.000039391107,0.000057734476,0.00006818143,8.9316796e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007624399,0.000030048455,0.0002879109,0.000023910725,0.00000818693,5.388494e-10,0.00005021334,0.000043686883,0.99501795,0.0035412984,0.00009787721,0.000822671],"study_design_scores_gemma":[0.0003571972,0.00014855452,0.0011062712,0.00018414042,0.00000217297,4.7368852e-7,0.00018274755,0.00037934285,0.9817982,0.015484356,0.0002634183,0.000093149974],"about_ca_topic_score_codex":0.0000021558128,"about_ca_topic_score_gemma":4.0050157e-8,"teacher_disagreement_score":0.013219777,"about_ca_system_score_codex":0.000033033684,"about_ca_system_score_gemma":0.000031156553,"threshold_uncertainty_score":0.24522252},"labels":[],"label_agreement":null},{"id":"W2334667019","doi":"10.1016/j.jpain.2016.01.274","title":"(367) Interrogating the role of peripheral opioid receptors using an optogenetic approach","year":2016,"lang":"en","type":"article","venue":"Journal of Pain","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"DAMGO; Nociceptor; Optogenetics; Medicine; Neuroscience; Nociception; Opioid; Pharmacology; Opioid receptor; μ-opioid receptor; Receptor; Anesthesia; Internal medicine; Biology","score_opus":0.0139564468293787,"score_gpt":0.24751711954572667,"score_spread":0.23356067271634798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2334667019","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9226685,0.0007651428,0.07625874,0.000023984841,0.0001475644,0.000050688457,0.0000014697597,0.0000014175773,0.0000824598],"genre_scores_gemma":[0.98469186,0.000051263713,0.014715876,0.000046026402,0.00043657087,0.00000100036,0.0000013504549,0.000015686612,0.00004037516],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989692,0.00029706632,0.0003339947,0.0001084264,0.00014953813,0.00014174741],"domain_scores_gemma":[0.99932134,0.000022704175,0.00032989442,0.0001502579,0.00011314162,0.0000626686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013511651,0.00009440029,0.00014509086,0.000031648688,0.00005418638,0.000016240947,0.00024313983,0.00007539403,0.000074773205],"category_scores_gemma":[0.00012821332,0.00005089347,0.00013275957,0.000044604494,0.000049214465,0.000007926334,0.000043022093,0.00007295722,2.3039189e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003827801,0.000038815127,0.0012023753,0.000005384222,0.000037988466,3.9269193e-7,0.00035455162,0.00027430974,0.97254646,0.000026062251,0.000022383672,0.025452992],"study_design_scores_gemma":[0.00033869265,0.0006964919,0.000057001616,0.000081268794,0.000021157972,0.000047074016,0.0033369372,0.002032401,0.9900966,0.0003040654,0.002877485,0.00011077505],"about_ca_topic_score_codex":0.0000060117122,"about_ca_topic_score_gemma":0.0000027974115,"teacher_disagreement_score":0.062023316,"about_ca_system_score_codex":0.000018512,"about_ca_system_score_gemma":0.00006281147,"threshold_uncertainty_score":0.20753755},"labels":[],"label_agreement":null},{"id":"W2334704772","doi":"10.1016/j.cjca.2011.07.453","title":"545 Cardioprotective effects mediated by AT1 receptor blockade and enhancing ang 1-7 in experimental heart failure in ACE2-null mice","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton","funders":"","keywords":"Medicine; Angiotensin II receptor type 1; Angiotensin II; Blockade; Receptor; Internal medicine; Heart failure; Endocrinology; Blocking (statistics); Fibrosis; Angiotensin-converting enzyme 2; Renin–angiotensin system; Pharmacology; Blood pressure; Coronavirus disease 2019 (COVID-19)","score_opus":0.00561490083983953,"score_gpt":0.19687891831901086,"score_spread":0.19126401747917132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2334704772","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99360216,0.0051306686,0.00048154197,0.00007952314,0.0003257991,0.00017657244,0.000012448355,0.0000017033755,0.00018956244],"genre_scores_gemma":[0.9988421,0.000062082254,0.00066202873,0.000094372524,0.00028291333,0.000012829407,0.000010901299,0.000020152469,0.000012584683],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875844,0.00027195396,0.00029922047,0.00023485023,0.000066903456,0.0003686247],"domain_scores_gemma":[0.9994017,0.00002694277,0.00009904554,0.00010632971,0.00006206258,0.00030390895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043826146,0.00016082868,0.00042179658,0.00018759712,0.000044750308,0.000010686142,0.00013118038,0.0002878092,0.00002076095],"category_scores_gemma":[0.00014680627,0.0001596586,0.00010366767,0.000097750555,0.00008433222,0.000009900527,0.000023879627,0.000274823,0.0000020610667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056054123,0.0000028993343,0.0067932936,0.000007799737,0.000060150203,0.000041164214,0.00048277288,0.000035509096,0.9912367,0.000004713593,0.0010819363,0.00019701669],"study_design_scores_gemma":[0.0009316514,0.00060381985,0.002101456,0.000055349035,0.0000114921495,0.00020111958,0.00093022553,0.0000030873796,0.97661257,0.000023557532,0.018337335,0.00018835715],"about_ca_topic_score_codex":0.0016188787,"about_ca_topic_score_gemma":0.0039663026,"teacher_disagreement_score":0.0172554,"about_ca_system_score_codex":0.0000977787,"about_ca_system_score_gemma":0.0002666698,"threshold_uncertainty_score":0.65106887},"labels":[],"label_agreement":null},{"id":"W2334972854","doi":"10.1097/fjc.0000000000000198","title":"Nuclear G Protein Signaling","year":2015,"lang":"en","type":"review","venue":"Journal of Cardiovascular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Heterotrimeric G protein; G protein-coupled receptor; Cell biology; Signal transduction; G protein; Biology; Chemistry","score_opus":0.038712438413370534,"score_gpt":0.3228429121020958,"score_spread":0.2841304736887253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2334972854","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027468015,0.9962598,0.0011580575,0.000007755789,0.0015700547,0.0005140524,0.000009507598,0.000007887516,0.00019817981],"genre_scores_gemma":[0.00010219575,0.99402285,0.001188827,0.00005088503,0.004339045,0.000020758069,0.000023313998,0.00012658942,0.00012552665],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99677646,0.0009244008,0.0010087021,0.00037145606,0.0005479258,0.00037107934],"domain_scores_gemma":[0.99795383,0.000015396625,0.0008664172,0.00036510493,0.00052382203,0.0002754227],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002558575,0.00044702194,0.002454296,0.00022789811,0.000068107394,0.00003844886,0.00066576304,0.00064111315,0.00025278496],"category_scores_gemma":[0.000066958724,0.00036049535,0.0041997205,0.00016832315,0.000064444765,0.000008136753,0.0001853516,0.00067320844,0.00003387656],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000850847,0.000092065675,4.6370094e-8,0.0029365725,0.01773802,0.0004205904,0.000026483385,0.0006054089,0.030928053,0.000020253765,0.011797757,0.93534964],"study_design_scores_gemma":[0.000729867,0.00044107367,4.13582e-9,0.0008847363,0.0049785404,0.0013215027,0.000016632823,0.0000025494937,0.0060727797,0.000019580753,0.9851818,0.0003509298],"about_ca_topic_score_codex":0.0000012521843,"about_ca_topic_score_gemma":4.0904197e-8,"teacher_disagreement_score":0.973384,"about_ca_system_score_codex":0.00009536381,"about_ca_system_score_gemma":0.0007569798,"threshold_uncertainty_score":0.9998847},"labels":[],"label_agreement":null},{"id":"W2335620420","doi":"10.1152/ajpcell.00261.2001","title":"EGF receptor transactivation is obligatory for protein synthesis stimulation by G protein-coupled receptors","year":2002,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"","keywords":"G protein-coupled receptor; Transactivation; Cell biology; Lysophosphatidic acid; Insulin-like growth factor 1 receptor; Receptor tyrosine kinase; Epidermal growth factor receptor; Epidermal growth factor; Biology; Receptor; Signal transduction; Phosphorylation; Chemistry; Biochemistry; Growth factor; Transcription factor","score_opus":0.008226952761868165,"score_gpt":0.21462589931691292,"score_spread":0.20639894655504476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2335620420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99306726,0.00033265984,0.005291227,0.0003221011,0.00026473915,0.0006383994,0.000040420848,0.0000152348275,0.00002793525],"genre_scores_gemma":[0.99318093,0.00014180725,0.0050927345,0.00035100518,0.0005802742,0.00015573086,0.0000644348,0.000067333494,0.00036577054],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977814,0.0003159103,0.00070692383,0.0005415359,0.00018342752,0.00047081173],"domain_scores_gemma":[0.99792707,0.000082937455,0.0011428186,0.0003287749,0.00035764833,0.00016077366],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003084142,0.00036157548,0.00069546874,0.00012670565,0.00016374058,0.000014962377,0.0003803843,0.00025094478,0.0007853992],"category_scores_gemma":[0.00012362759,0.00032194663,0.00040876094,0.0002029787,0.00030362958,0.000028399232,0.000031258558,0.00026186858,0.000018584242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008071508,0.0003019243,0.0000045874563,0.000043961325,0.00015435883,1.4929049e-7,0.00014064615,0.00032412054,0.9879354,0.000011094832,0.005529719,0.00474689],"study_design_scores_gemma":[0.00096909265,0.0038311,0.000046272122,0.00004513592,0.000047231144,0.0000031869113,0.0002545152,0.0007820634,0.9836399,0.00033404105,0.00968818,0.00035929054],"about_ca_topic_score_codex":0.000015786498,"about_ca_topic_score_gemma":4.7557148e-7,"teacher_disagreement_score":0.0043875994,"about_ca_system_score_codex":0.000051192106,"about_ca_system_score_gemma":0.000070482,"threshold_uncertainty_score":0.9999233},"labels":[],"label_agreement":null},{"id":"W2336062311","doi":"10.1016/j.bbamcr.2016.04.010","title":"Topogenesis and cell surface trafficking of GPR34 are facilitated by positive-inside rule that effects through a tri-basic motif in the first intracellular loop","year":2016,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Research Council Canada","keywords":"Intracellular; Epitope; Cell biology; Transmembrane domain; Extracellular; Mutant; Biology; Transmembrane protein; Structural motif; Protein folding; Biophysics; Biochemistry; Receptor; Genetics; Antibody; Gene","score_opus":0.02028767724104862,"score_gpt":0.26927943153876505,"score_spread":0.24899175429771642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2336062311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937841,0.0027230794,0.0010972188,0.001137154,0.000051120373,0.0008856548,0.00011178341,0.000016461505,0.00019341375],"genre_scores_gemma":[0.9978233,0.0012291399,0.0003907451,0.00016615436,0.000039413593,0.000044893222,0.0000894595,0.00007205678,0.00014486886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99604136,0.0010311423,0.00040206584,0.0009710058,0.0007567168,0.00079771865],"domain_scores_gemma":[0.9983065,0.00039700154,0.00019902496,0.00076677173,0.00019230312,0.00013837051],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010806154,0.000426988,0.00045282376,0.00011887478,0.0002137273,0.000097976656,0.0006836115,0.00034153523,0.000015223477],"category_scores_gemma":[0.00011209414,0.00030130768,0.00023470918,0.00046939153,0.00038061725,0.000025680529,0.00031215313,0.00035279914,0.00001077591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022102526,0.00039712072,0.00004909195,0.00020259953,0.00006252051,0.000039015627,0.00048323272,0.000023706445,0.99767125,0.00002716522,0.0003957145,0.0004275788],"study_design_scores_gemma":[0.001344959,0.00063979405,0.00037793585,0.00016608117,0.000033316515,0.000003956687,0.00040317173,0.000059644288,0.99607855,0.0000946936,0.00042482928,0.00037304676],"about_ca_topic_score_codex":0.0001718663,"about_ca_topic_score_gemma":0.000014412555,"teacher_disagreement_score":0.004039155,"about_ca_system_score_codex":0.00004874925,"about_ca_system_score_gemma":0.00011778906,"threshold_uncertainty_score":0.9999439},"labels":[],"label_agreement":null},{"id":"W2342641238","doi":"10.1152/ajplung.2000.278.1.l59","title":"Protein kinase C is involved in enhanced airway smooth muscle cell growth in hyperresponsive rats","year":2000,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Protein kinase C; Kinase; Cell growth; Cell biology; Protein kinase A; Threonine; Phosphorylation; Blot; Chemistry; Biology; Molecular biology; Biochemistry; Serine","score_opus":0.003426406457298971,"score_gpt":0.20644261053311017,"score_spread":0.2030162040758112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2342641238","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973074,0.0017205506,0.00035879103,0.000112498106,0.00008496344,0.00028410828,0.0000070065835,0.000005390889,0.000119243785],"genre_scores_gemma":[0.99724907,0.0007118433,0.00088508124,0.0008616763,0.00013054196,0.000024945308,0.000032187454,0.00004525856,0.0000593717],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99745405,0.00062825205,0.00062084425,0.0006032984,0.00014847018,0.0005450697],"domain_scores_gemma":[0.998981,0.000033873264,0.0003751193,0.0003110121,0.00013442083,0.00016458005],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031389718,0.00036112333,0.0007357776,0.00021920537,0.000058753438,0.000013018313,0.00033594397,0.00020621417,0.00016590302],"category_scores_gemma":[0.000043648404,0.0003331208,0.00023441027,0.00030826908,0.00035633595,0.00001764627,0.000092690476,0.00041504292,0.000006253314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008644551,0.00020992657,0.000034111054,0.00003350238,0.00004375801,0.00004148822,0.00029414866,0.00031394974,0.9949199,0.000026569687,0.000047038797,0.0031711746],"study_design_scores_gemma":[0.0014084021,0.0017904704,0.0021074598,0.00006347957,0.000023196464,0.000005945097,0.00039678995,0.00013286778,0.9926056,0.0005962028,0.000510995,0.00035857887],"about_ca_topic_score_codex":0.00011241559,"about_ca_topic_score_gemma":0.000010190671,"teacher_disagreement_score":0.0028125958,"about_ca_system_score_codex":0.000034126042,"about_ca_system_score_gemma":0.00015160727,"threshold_uncertainty_score":0.9999121},"labels":[],"label_agreement":null},{"id":"W2344414687","doi":"10.1074/jbc.m115.709659","title":"Rearrangement of the Extracellular Domain/Extracellular Loop 1 Interface Is Critical for Thyrotropin Receptor Activation","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Else Kröner-Fresenius-Stiftung; European Social Fund; Deutsche Forschungsgemeinschaft","keywords":"Extracellular; Chemistry; Receptor; Biophysics; G protein-coupled receptor; Transmembrane domain; Homology modeling; Ligand (biochemistry); Docking (animal); Cell biology; Biochemistry; Biology; Enzyme; Medicine","score_opus":0.02330442095577938,"score_gpt":0.2702991849332481,"score_spread":0.24699476397746872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2344414687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9209605,0.0013095353,0.075378075,0.00198487,0.00015284462,0.00012990585,0.000026218762,0.0000029157106,0.000055136574],"genre_scores_gemma":[0.9947475,0.0002042038,0.003841735,0.00007700712,0.00044645293,0.000008305701,0.0000046369637,0.000012828547,0.00065731595],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988229,0.00006282216,0.0005053193,0.00021491863,0.00018693772,0.00020709613],"domain_scores_gemma":[0.99895257,0.00008188775,0.00037452573,0.00022941497,0.00027781638,0.00008379096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044355862,0.00015103514,0.000231583,0.000011806312,0.000060267776,0.000012267336,0.00034696187,0.00028204947,0.0005335491],"category_scores_gemma":[0.0005417112,0.00007549272,0.00032969163,0.000046770703,0.0001567622,0.0000071806057,0.00008501249,0.00012556872,0.0000014909357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003202682,0.000090607246,0.00015867526,0.000038114464,0.000053770043,4.5439032e-7,0.000016531463,0.00000299094,0.9959927,0.00010015386,0.0020770277,0.0011486816],"study_design_scores_gemma":[0.00058810186,0.00041107647,0.00004006096,0.00012864417,0.000015460117,0.000012144593,0.00013470105,0.000003097486,0.9625439,0.00062536745,0.035382662,0.000114808674],"about_ca_topic_score_codex":5.0681115e-7,"about_ca_topic_score_gemma":4.444747e-8,"teacher_disagreement_score":0.07378702,"about_ca_system_score_codex":0.00003102669,"about_ca_system_score_gemma":0.000050709186,"threshold_uncertainty_score":0.5841989},"labels":[],"label_agreement":null},{"id":"W234567464","doi":"10.1016/j.bmcl.2015.05.036","title":"Use of molecular modeling aided design to dial out hERG liability in adenosine A2A receptor antagonists","year":2015,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"","keywords":"hERG; Chemistry; Docking (animal); Molecular model; Lead compound; Quinazoline; Pharmacology; Stereochemistry; Combinatorial chemistry; Biochemistry; Biophysics; Potassium channel; In vitro","score_opus":0.06421880525581727,"score_gpt":0.26592452082491325,"score_spread":0.20170571556909597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W234567464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9242268,0.000281094,0.07355903,0.0013760509,0.00023181038,0.00027329155,0.00001524173,0.000018663139,0.00001797364],"genre_scores_gemma":[0.99155986,0.000026883845,0.0069585512,0.0008502358,0.00038856379,0.000020507217,0.00009279441,0.000048251357,0.000054326923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978782,0.000104813495,0.00054809474,0.0006179948,0.0004222271,0.00042868],"domain_scores_gemma":[0.9988371,0.000024853709,0.00012851396,0.0005030129,0.00014916509,0.00035733805],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006120322,0.00030581685,0.0003824303,0.000047856087,0.000032782104,0.000025338182,0.0003378415,0.0002427909,0.0000862467],"category_scores_gemma":[0.00067600294,0.00030215684,0.000102313556,0.00019104802,0.000086177104,0.00001117293,0.00013928846,0.00020664392,0.00000924932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037599835,0.00007597271,0.00028061884,0.000045711306,0.000035381916,0.000029077486,0.0002209544,0.002441806,0.9945434,0.000001418258,0.0016964448,0.0002532239],"study_design_scores_gemma":[0.0008082059,0.00015184906,0.000014192225,0.000089054374,0.00002574558,0.000015208302,0.00016756728,0.0008822744,0.9967724,0.000014545968,0.00074669166,0.0003122326],"about_ca_topic_score_codex":0.00009758756,"about_ca_topic_score_gemma":0.000004071019,"teacher_disagreement_score":0.06733304,"about_ca_system_score_codex":0.0001223461,"about_ca_system_score_gemma":0.00021173597,"threshold_uncertainty_score":0.9999431},"labels":[],"label_agreement":null},{"id":"W2345966590","doi":"10.1038/nature17668","title":"Activation of the A2A adenosine G-protein-coupled receptor by conformational selection","year":2016,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":365,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"Allosteric regulation; Chemistry; Agonist; G protein-coupled receptor; Inverse agonist; Population; Partial agonist; Biophysics; Receptor; Adenosine A2A receptor; Ligand (biochemistry); Adenosine receptor; Stereochemistry; Biochemistry; Biology","score_opus":0.003245916053936517,"score_gpt":0.20877391170153312,"score_spread":0.2055279956475966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2345966590","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929481,0.00015181222,0.005470121,0.0009192089,0.00016043369,0.00015011922,0.000021375945,0.0000061830506,0.00017262102],"genre_scores_gemma":[0.9980628,0.0000148317895,0.0003105443,0.00019476398,0.0001452034,0.000009020886,0.000053965716,0.0000071543277,0.0012017094],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99955547,0.00002110219,0.000104894556,0.00010312083,0.00013690435,0.000078488614],"domain_scores_gemma":[0.9996606,0.000006109502,0.0000972658,0.00009444886,0.00012438397,0.000017201652],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008448141,0.00006400638,0.00005323425,0.00001264655,0.00005271111,0.000007365669,0.00009670147,0.00048934494,0.00024913848],"category_scores_gemma":[0.00008170458,0.000035414952,0.00004686158,0.000063925814,0.000018789679,0.000008102113,0.000022486449,0.0001752878,0.0000032892606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000398257,0.000010308442,0.000084324834,0.000004494399,0.000013075961,3.85383e-9,0.0000069305397,0.000002922451,0.9899722,0.0005637747,0.008252291,0.0010498915],"study_design_scores_gemma":[0.0002765667,0.000055109846,0.00020322348,0.000025198924,0.0000027186948,8.056822e-7,0.000009865508,0.000028659155,0.96836287,0.00009658437,0.03088366,0.00005472957],"about_ca_topic_score_codex":0.000003587535,"about_ca_topic_score_gemma":0.0000012827243,"teacher_disagreement_score":0.02263137,"about_ca_system_score_codex":0.000013874439,"about_ca_system_score_gemma":0.00003619265,"threshold_uncertainty_score":0.37742764},"labels":[],"label_agreement":null},{"id":"W2346093421","doi":"10.7554/elife.11685","title":"Allosteric modulation in monomers and oligomers of a G protein-coupled receptor","year":2016,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; Pennsylvania Department of Health; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Allosteric regulation; Chemistry; Allosteric enzyme; Biophysics; Intramolecular force; Steric effects; G protein-coupled receptor; Supramolecular chemistry; Monomer; Muscarinic acetylcholine receptor; Stereochemistry; Receptor; Biochemistry; Crystallography; Biology; Crystal structure; Polymer; Organic chemistry","score_opus":0.0073032897785631,"score_gpt":0.2139467517746163,"score_spread":0.2066434619960532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2346093421","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99789774,0.00021484731,0.0015339851,0.000093057315,0.000042802425,0.0001472907,0.0000033654142,0.0000031859497,0.0000637376],"genre_scores_gemma":[0.9983688,0.000150458,0.0011720625,0.000030876436,0.0000434765,0.00001752336,0.0000067844144,0.000009258915,0.00020074497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995138,0.00002070589,0.00014104751,0.00015629063,0.000067114684,0.00010105987],"domain_scores_gemma":[0.99978137,0.000004001912,0.000055827357,0.00009704086,0.000027108199,0.00003462544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001220164,0.00006495348,0.000088975336,0.000036683286,0.0000113861215,0.0000035641299,0.000044026576,0.00006388383,0.000052788382],"category_scores_gemma":[0.000033588556,0.00004861862,0.00002425689,0.000042517997,0.000023360159,0.0000035219205,0.000030048544,0.000017151335,0.000003067104],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004690377,0.000010231492,0.0011463905,0.0000072051566,0.0000081790395,1.5957724e-7,0.000032412125,0.000011686991,0.99248075,0.00004610897,0.000014966296,0.006194989],"study_design_scores_gemma":[0.00053833023,0.00014829612,0.0019251521,0.00003484989,0.0000018446024,6.3703953e-7,0.00003857979,0.00020090517,0.9953454,0.000029958235,0.0016452706,0.000090785485],"about_ca_topic_score_codex":0.000016718557,"about_ca_topic_score_gemma":0.0000056751423,"teacher_disagreement_score":0.0061042034,"about_ca_system_score_codex":0.00000759043,"about_ca_system_score_gemma":0.000016896716,"threshold_uncertainty_score":0.19826098},"labels":[],"label_agreement":null},{"id":"W2346281040","doi":"10.1038/srep25180","title":"The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway","year":2016,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Mitsubishi Foundation; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Neurogenesis; Cell biology; G protein; Heterotrimeric G protein; Gs alpha subunit; Signal transduction; Gq alpha subunit; Receptor; Biology; G protein-coupled receptor; Chemistry; Biochemistry","score_opus":0.008135028326615602,"score_gpt":0.2109342212442241,"score_spread":0.20279919291760848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2346281040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917515,0.00023497733,0.0011782396,0.00030766905,0.005808734,0.00061072625,0.000007365131,0.000014577687,0.000086232445],"genre_scores_gemma":[0.99550277,0.000015575843,0.00020184477,0.000009815333,0.0005394901,0.000075356416,0.00004871982,0.0000203983,0.0035860476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99807733,0.0001225356,0.0004950794,0.00055092364,0.00045274862,0.00030136356],"domain_scores_gemma":[0.99844205,0.000035082918,0.0004527179,0.0007541932,0.00026212985,0.000053849606],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00093962444,0.0001594418,0.00013329915,0.000021695985,0.00055240217,0.00013792775,0.00025908952,0.00010567476,0.000106879284],"category_scores_gemma":[0.00040270376,0.000073573094,0.00015941136,0.00015851567,0.0003670929,0.000013641856,0.00009478303,0.000060246588,0.000005668645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005264833,0.000029511864,0.00015854884,0.0000063351454,0.000029459503,0.0000019030007,0.000086160464,0.0000061495757,0.99497193,0.00024674332,0.0016643073,0.0027463124],"study_design_scores_gemma":[0.00016517722,0.00010285966,0.00013049538,0.000024399553,0.000010637504,0.000014656461,0.00004928476,0.000020371577,0.9537587,0.0023638168,0.043246016,0.000113584836],"about_ca_topic_score_codex":0.0000122187475,"about_ca_topic_score_gemma":0.000020043797,"teacher_disagreement_score":0.04158171,"about_ca_system_score_codex":0.0000157015,"about_ca_system_score_gemma":0.00022125054,"threshold_uncertainty_score":0.4248687},"labels":[],"label_agreement":null},{"id":"W2378219007","doi":"10.1039/9781782622499-00202","title":"Protein Interactions with Dopamine Receptors as Potential New Drug Targets for Treating Schizophrenia","year":2015,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Dopamine receptor D2; Dopamine; G protein-coupled receptor; Dopamine receptor; D2-like receptor; Receptor; Neuroscience; Biology; Dopamine receptor D3; D1-like receptor; Signal transduction; Schizophrenia (object-oriented programming); Pharmacology; Cell biology; Medicine; Biochemistry; Psychiatry","score_opus":0.012537791504637175,"score_gpt":0.24212062482090616,"score_spread":0.22958283331626897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2378219007","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.018913276,0.006450136,0.23027498,0.0012660533,0.0033055395,0.0071799513,0.00030709727,0.00031378499,0.7319892],"genre_scores_gemma":[0.01493999,0.000041847095,0.027556518,0.000051318744,0.0018118077,0.00007467123,0.001100271,0.00014524927,0.95427835],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99856794,0.000014055101,0.0003208985,0.00060910743,0.00021554306,0.00027248374],"domain_scores_gemma":[0.99893475,0.0000077916875,0.0002524964,0.00032272408,0.00025687204,0.0002253533],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001328392,0.00043436952,0.0003367515,0.000084837106,0.0001285822,0.000064124535,0.00018977073,0.00027976057,0.0017347343],"category_scores_gemma":[0.00003509042,0.00034899308,0.00021205057,0.000017993256,0.00003700557,0.000007290388,0.000085385414,0.0002083796,0.00004750008],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025827244,0.00006477029,7.5060586e-7,0.00008622915,0.00078386546,0.000018754403,0.00007111188,0.0001895097,0.8566508,0.02723185,0.062376596,0.04994299],"study_design_scores_gemma":[0.0014716513,0.0009657618,7.829292e-8,0.00018908389,0.00012090829,0.00005367076,0.000053217114,0.000045810408,0.33550358,0.0063854773,0.65455,0.00066071324],"about_ca_topic_score_codex":0.00009465291,"about_ca_topic_score_gemma":0.00014712028,"teacher_disagreement_score":0.59217346,"about_ca_system_score_codex":0.0000410731,"about_ca_system_score_gemma":0.00035601022,"threshold_uncertainty_score":0.9998962},"labels":[],"label_agreement":null},{"id":"W2393982803","doi":"","title":"Characteristics of sleep-wake cycles in mice lacking prostanoid DP receptors","year":2006,"lang":"en","type":"article","venue":"Zhongguo linchuang yaolixue yu zhiliaoxue","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"L'Alliance Boviteq","funders":"","keywords":"Non-rapid eye movement sleep; Circadian rhythm; Pentobarbital; Endocrinology; Slow-wave sleep; Wakefulness; Internal medicine; Sleep (system call); Prostanoid; Electroencephalography; Chemistry; Receptor; Medicine; Anesthesia; Psychology; Neuroscience","score_opus":0.006086623595741055,"score_gpt":0.2176289708927764,"score_spread":0.21154234729703536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2393982803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99437785,0.0007630957,0.0021186657,0.00007401977,0.00064285536,0.00036003542,0.000069547066,0.000034938814,0.0015589964],"genre_scores_gemma":[0.9955641,0.00015701585,0.0018360467,0.000097383265,0.00074961776,0.00003391602,0.00052556035,0.000072159615,0.00096421933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977307,0.00010912283,0.0007624721,0.0005843476,0.0002790429,0.00053431647],"domain_scores_gemma":[0.99897796,0.00003483022,0.00033291403,0.00041224188,0.00014999913,0.000092078044],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044999967,0.0003401826,0.00044502475,0.00016754384,0.00009625572,0.00004762545,0.00034590132,0.00035502913,0.000110263725],"category_scores_gemma":[0.000119685836,0.00035008675,0.00018943202,0.0002822858,0.0001059911,0.00001634272,0.00014997624,0.00023165085,0.000020321811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009507957,0.00017709073,0.030725557,0.00008290043,0.000029964951,0.000013906359,0.000110592075,0.00023109511,0.9630072,0.00087012735,0.00033721942,0.0043192315],"study_design_scores_gemma":[0.0009146878,0.00021377722,0.017375616,0.00012959707,0.00002788925,0.000017008992,0.00014934564,0.0003115535,0.9649839,0.0005228562,0.014781039,0.0005727529],"about_ca_topic_score_codex":0.00028021538,"about_ca_topic_score_gemma":0.00021716174,"teacher_disagreement_score":0.01444382,"about_ca_system_score_codex":0.00004590528,"about_ca_system_score_gemma":0.000087536304,"threshold_uncertainty_score":0.9998951},"labels":[],"label_agreement":null},{"id":"W2396287619","doi":"10.1159/000480975","title":"Diurnal Rhythm of β-Endorphin in Neonates","year":2019,"lang":"en","type":"article","venue":"Developmental Pharmacology and Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Circadian rhythm; Diurnal temperature variation; beta-Endorphin; Gestational age; Endocrinology; Internal medicine; Rhythm; Birth weight; Medicine; Pregnancy; Biology","score_opus":0.009429927026335761,"score_gpt":0.25627483695530173,"score_spread":0.24684490992896596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2396287619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99803376,0.0009905372,0.000064515916,0.000051937895,0.00025263632,0.0001164899,0.0000043901628,0.0000028430745,0.00048291023],"genre_scores_gemma":[0.99766713,0.00052883447,0.00088722917,0.0006365676,0.000033717573,0.0000056021213,0.00001646276,0.000009209826,0.00021526587],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994559,0.00003570846,0.00016181744,0.0001538931,0.000051025243,0.00014163522],"domain_scores_gemma":[0.99985814,0.000012928333,0.000047653168,0.000036803616,0.000018173341,0.000026299565],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012990349,0.00009038711,0.000116862546,0.000041683143,0.000023317809,0.0000036551123,0.00006657123,0.000088738336,0.0003482066],"category_scores_gemma":[0.0000012243466,0.000084080835,0.000021680271,0.000049161517,0.00004269531,0.0000025312333,0.00005745835,0.00008154339,0.000006713402],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000118498974,0.00003882775,0.027876984,0.000011650365,0.00006776322,0.000002780205,0.00013540075,0.000019111278,0.966064,0.00011688614,0.00002612482,0.0055219675],"study_design_scores_gemma":[0.0011949245,0.00012478718,0.005470486,0.000007924774,0.0000094350235,0.00004023949,0.00016936092,0.00010415641,0.98296183,0.00025886242,0.009535583,0.00012238821],"about_ca_topic_score_codex":0.000003830684,"about_ca_topic_score_gemma":0.0000043347745,"teacher_disagreement_score":0.022406498,"about_ca_system_score_codex":0.000008444113,"about_ca_system_score_gemma":0.00004285307,"threshold_uncertainty_score":0.38126183},"labels":[],"label_agreement":null},{"id":"W2400226594","doi":"","title":"Beta-blockers as antiarrhythmic agents.","year":2006,"lang":"en","type":"article","venue":"PubMed","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Medicine; BETA (programming language); Heart failure; Cardiology; Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Adrenergic receptor; Internal medicine; Pharmacology; Adrenergic; Sudden death; Atrial fibrillation; Receptor; Propranolol","score_opus":0.010029457383886158,"score_gpt":0.20747094400598454,"score_spread":0.19744148662209837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2400226594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900058,0.0005630525,0.0005990796,0.00031241475,0.00030756812,0.0003113392,0.0000064505657,0.000022255399,0.007872056],"genre_scores_gemma":[0.9936952,0.000038747803,0.00037310066,0.00026927533,0.0004964076,0.00023018898,0.00007755186,0.000020299509,0.0047992305],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991782,0.000023308048,0.00013745516,0.0002488341,0.00010950094,0.00030272498],"domain_scores_gemma":[0.9996662,0.0000028138409,0.00004720646,0.0001896271,0.000027432849,0.000066721834],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001399372,0.000107571934,0.00009167261,0.000027224685,0.000059560876,0.000028132326,0.00010552552,0.00007920185,0.000100421756],"category_scores_gemma":[0.0000140028615,0.000102118625,0.00008980641,0.00005412124,0.000023875013,0.0000022205206,0.000044728004,0.000044835404,0.000031165862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013904151,0.00019006914,0.0060710306,0.000032299315,0.0002019498,0.000068997615,0.000023670673,0.00031743033,0.7682487,0.0031454354,0.10997667,0.111584745],"study_design_scores_gemma":[0.0003343819,0.00002661063,0.008226345,0.0000015716582,0.0000139987405,0.000022848026,0.000013697267,0.000012640301,0.71142477,0.00040117197,0.27934918,0.00017278989],"about_ca_topic_score_codex":0.000063386266,"about_ca_topic_score_gemma":0.000009286312,"teacher_disagreement_score":0.1693725,"about_ca_system_score_codex":0.000009242559,"about_ca_system_score_gemma":0.000015271353,"threshold_uncertainty_score":0.41642767},"labels":[],"label_agreement":null},{"id":"W2400237868","doi":"10.1007/978-1-61779-160-4_18","title":"Visualizing Receptor Endocytosis and Trafficking","year":2011,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Internalization; G protein-coupled receptor; Endocytosis; Receptor; Cell biology; Endosome; Transmembrane domain; Transmembrane protein; Small molecule; Chemistry; Biology; Signal transduction; Biochemistry","score_opus":0.039935925370151344,"score_gpt":0.37355079054422663,"score_spread":0.3336148651740753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2400237868","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.32267725,0.0015673933,0.6742592,0.0000143157,0.00020922581,0.00012714653,0.0000025675329,0.000015493937,0.0011274323],"genre_scores_gemma":[0.22750092,0.00024803274,0.7717885,0.00027491577,0.00005908098,0.000033860553,0.000020972728,0.00003129223,0.00004245164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981167,0.000696569,0.00028314983,0.00051183824,0.00004514392,0.00034660916],"domain_scores_gemma":[0.99953115,0.00003168755,0.00008008194,0.00024767857,0.000032118285,0.00007727321],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009668889,0.00019322595,0.0002462077,0.000114249735,0.00005193766,0.0000115966595,0.00017856354,0.00027329847,0.00012634044],"category_scores_gemma":[0.0002123084,0.00018722686,0.000083276536,0.00012157434,0.000097940254,0.0000028054103,0.00015488194,0.000136654,0.0000028514148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037126953,0.000028426355,0.0010474233,0.0000079222455,0.000030181736,0.0000049668784,0.00018838095,0.0000030290835,0.9638176,0.0034580997,0.000009888028,0.031366967],"study_design_scores_gemma":[0.00035123026,0.00029105193,0.0000877061,0.000012961832,0.000010570871,0.000017934097,0.0001401925,0.00006777996,0.9908147,0.0017869042,0.006185193,0.00023380943],"about_ca_topic_score_codex":0.000040934327,"about_ca_topic_score_gemma":0.000006556899,"teacher_disagreement_score":0.09752929,"about_ca_system_score_codex":0.000011104736,"about_ca_system_score_gemma":0.000023634419,"threshold_uncertainty_score":0.76348895},"labels":[],"label_agreement":null},{"id":"W2402409849","doi":"10.1007/978-1-4939-0956-8_7","title":"G Protein-Coupled Receptor Accessory Proteins and Signaling: Pharmacogenomic Insights","year":2014,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Toronto; Canada Research Chairs","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Biology; G protein; Regulator of G protein signaling; Genetics; Signal transduction; Computational biology; Cell biology; GTPase-activating protein","score_opus":0.04055626852597994,"score_gpt":0.4063347284368998,"score_spread":0.36577845991091984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2402409849","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008582349,0.6824382,0.31465942,0.0000075016724,0.00028079844,0.001642503,0.000013832944,0.000021059568,0.0000784383],"genre_scores_gemma":[0.000044039098,0.68584967,0.31222254,0.00010480415,0.0003262223,0.0008373742,0.00031877428,0.00014297613,0.00015359386],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99312085,0.0035065315,0.0010921158,0.0015011012,0.000120346114,0.0006590764],"domain_scores_gemma":[0.9982962,0.00010593396,0.0006104955,0.0007111289,0.000082695056,0.0001935185],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0019397808,0.0008599907,0.0020625785,0.00037911194,0.00010663094,0.000057598198,0.00073432946,0.001445075,0.00011621215],"category_scores_gemma":[0.00041654822,0.00073246507,0.00051881943,0.00029002147,0.00020004461,0.000004529574,0.00052868476,0.0006794989,0.000016118503],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020243026,0.0000328022,6.7116054e-7,0.0014752672,0.00016059114,0.000007449688,0.0000128900265,0.0000022113604,0.7080618,0.00036782876,0.000007691561,0.28985056],"study_design_scores_gemma":[0.00043025208,0.00030309873,4.2330402e-8,0.00091393176,0.00015338282,0.000023692084,0.000005875283,0.000033950877,0.30364677,0.000739855,0.6930422,0.00070692034],"about_ca_topic_score_codex":0.000017647937,"about_ca_topic_score_gemma":0.0000027586548,"teacher_disagreement_score":0.6930345,"about_ca_system_score_codex":0.00006024689,"about_ca_system_score_gemma":0.00027273965,"threshold_uncertainty_score":0.9998513},"labels":[],"label_agreement":null},{"id":"W2403313607","doi":"10.1002/bdd.2016","title":"The pharmacokinetics of dronedarone in normolipidemic and hyperlipidemic rats","year":2016,"lang":"en","type":"article","venue":"Biopharmaceutics & Drug Disposition","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Innovative Research Group Project of the National Natural Science Foundation of China","keywords":"Pharmacokinetics; Cmax; Dronedarone; Volume of distribution; Bioavailability; Pharmacology; Oral administration; Hyperlipidemia; Chemistry; Medicine; Endocrinology; Internal medicine","score_opus":0.00864608973697058,"score_gpt":0.2658121619689345,"score_spread":0.2571660722319639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2403313607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938817,0.0038446586,0.0010385448,0.00063749973,0.00029263337,0.00020556034,0.000023902747,0.000007772107,0.000067747445],"genre_scores_gemma":[0.9919952,0.0072224834,0.00020979624,0.00015793492,0.0001890595,0.000018023247,0.000016377546,0.000019622337,0.00017148977],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989398,0.00011125788,0.0003254057,0.00024484843,0.00012871216,0.0002499804],"domain_scores_gemma":[0.9994978,0.00006476367,0.00012430814,0.0001769411,0.000058926333,0.00007729441],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046911277,0.00014513488,0.00013644577,0.00004461672,0.00008488657,0.000013070412,0.00014723328,0.000082883525,0.000015348638],"category_scores_gemma":[0.00003528249,0.000093392395,0.00005354611,0.00008349119,0.00012901545,0.000007900135,0.0000845599,0.00007782539,0.000003848906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016911254,0.000029248977,0.0019697791,0.000016378943,0.00002062565,8.4035787e-7,0.00003808526,0.000014247315,0.98130405,0.00021724563,0.00024379318,0.015976572],"study_design_scores_gemma":[0.0008780572,0.00006313884,0.0012865847,0.000050512277,0.000029455345,0.0000075164817,0.000050354403,0.00036452952,0.9896947,0.00023049598,0.007196781,0.000147878],"about_ca_topic_score_codex":0.0000088045,"about_ca_topic_score_gemma":0.000010186719,"teacher_disagreement_score":0.015828695,"about_ca_system_score_codex":0.00002371652,"about_ca_system_score_gemma":0.000031390075,"threshold_uncertainty_score":0.38084313},"labels":[],"label_agreement":null},{"id":"W2404001249","doi":"10.1016/bs.mie.2014.12.013","title":"Expression of G Protein-Coupled Receptors in Mammalian Cells","year":2015,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Manitoba Medical Service Foundation; Research Manitoba; Manitoba Health Research Council","keywords":"G protein-coupled receptor; Biology; Receptor; Transfection; Heterologous expression; Cell biology; Computational biology; Cell; Extracellular; Heterologous; Intracellular; Membrane protein; Gene; Biochemistry; Membrane; Recombinant DNA","score_opus":0.044937334197716526,"score_gpt":0.3763365467262813,"score_spread":0.3313992125285648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2404001249","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89631224,0.0015400008,0.09725481,0.00014248556,0.0024042688,0.0010634823,0.000010147767,0.000033255357,0.0012393317],"genre_scores_gemma":[0.2337654,0.000094959614,0.7646978,0.0002872726,0.00017849969,0.00029877728,0.00003640012,0.0000935725,0.00054735213],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.98437226,0.010957304,0.0017137114,0.0015014042,0.0002843318,0.0011709896],"domain_scores_gemma":[0.99704874,0.00081724726,0.00059500145,0.0011131187,0.00016856582,0.0002573259],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.012764668,0.00066406385,0.0014778159,0.001015399,0.00005449611,0.00001477811,0.0009358661,0.0017942318,0.00034565237],"category_scores_gemma":[0.0031498617,0.00065452664,0.00023702794,0.0008371187,0.0004622494,0.00001894062,0.00048896595,0.0011011985,0.000013913023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00095686456,0.000496759,0.0018465117,0.00005367068,0.000023972618,0.000085078114,0.00057726045,0.0013948058,0.97808474,0.0009287081,0.00020303999,0.015348569],"study_design_scores_gemma":[0.0029406792,0.0019040457,0.0017123815,0.00012726923,0.000014068517,0.00005805287,0.00057223364,0.00018132504,0.9744592,0.011154171,0.00624898,0.00062760536],"about_ca_topic_score_codex":0.000461161,"about_ca_topic_score_gemma":0.0005233783,"teacher_disagreement_score":0.667443,"about_ca_system_score_codex":0.00018934494,"about_ca_system_score_gemma":0.00027151062,"threshold_uncertainty_score":0.9995906},"labels":[],"label_agreement":null},{"id":"W2404724518","doi":"10.1007/978-1-61779-160-4_23","title":"Study of G Protein-Coupled Receptor/β-arrestin Interactions Within Endosomes Using FRAP","year":2011,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Endosome; Arrestin; Fluorescence recovery after photobleaching; Cell biology; Yellow fluorescent protein; Chemistry; Scaffold protein; Receptor; G protein; HEK 293 cells; Intracellular; Biology; Signal transduction; Biochemistry","score_opus":0.06786797856907373,"score_gpt":0.3944787752244923,"score_spread":0.3266107966554186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2404724518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.64604664,0.0002305825,0.35285583,0.000003197151,0.00029494273,0.00040478676,0.0000026947362,0.0000086356995,0.00015269007],"genre_scores_gemma":[0.52947795,0.0000064162223,0.47033462,0.00002437615,0.000033932316,0.000059182534,0.000010469039,0.000023364404,0.0000296802],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99731296,0.0012115188,0.00059003866,0.0005173885,0.000079533405,0.00028854643],"domain_scores_gemma":[0.9990707,0.000032368687,0.00028079608,0.00045601997,0.0000980166,0.00006209697],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001093924,0.0002283965,0.00038391884,0.00019085767,0.000052746313,0.0000069195953,0.0003002679,0.00021327798,0.00016968403],"category_scores_gemma":[0.00040003558,0.00021386825,0.000113172086,0.00023809493,0.00009270784,0.0000044184453,0.00018801553,0.0002174036,0.0000018091811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000115158095,0.00033209266,0.0038474288,0.000009304749,0.00009225738,0.000008541954,0.00064931734,0.00007510699,0.9923778,0.00052864844,0.0000011603835,0.001963158],"study_design_scores_gemma":[0.0006851681,0.00093307835,0.00011765646,0.000028932578,0.000024448536,0.000011566865,0.0010762793,0.0003507919,0.99521947,0.0011819056,0.00014561489,0.00022506411],"about_ca_topic_score_codex":0.00032317635,"about_ca_topic_score_gemma":0.000052092102,"teacher_disagreement_score":0.11747879,"about_ca_system_score_codex":0.000018587642,"about_ca_system_score_gemma":0.00006516708,"threshold_uncertainty_score":0.8721294},"labels":[],"label_agreement":null},{"id":"W2405852961","doi":"10.1007/978-1-4939-1755-6_8","title":"High Resolution Imaging and Function of Nuclear G Protein-Coupled Receptors (GPCRs)","year":2014,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Hôpital Maisonneuve-Rosemont; Université de Sherbrooke; McGill University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Internalization; Cell biology; Nucleus; Confocal microscopy; Receptor; Nuclear transport; Inner membrane; Biology; Nuclear lamina; Cell nucleus; Nuclear membrane; Chemistry; Nuclear protein; Signal transduction; Transcription factor; Gene; Biochemistry","score_opus":0.008416533663112614,"score_gpt":0.289838784147859,"score_spread":0.2814222504847464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2405852961","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.38499632,0.00040584878,0.61409205,0.0000559084,0.00019688378,0.00014002365,0.0000010537308,0.000008422691,0.00010350216],"genre_scores_gemma":[0.4907377,0.00004381209,0.5088789,0.00016450523,0.00007224716,0.000018803088,0.000030073292,0.000025868276,0.000028107563],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819595,0.0008000511,0.00030111638,0.00041268137,0.000056998815,0.00023322756],"domain_scores_gemma":[0.9994689,0.000025308707,0.0001359707,0.00026311303,0.00005964538,0.000047045043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013812176,0.0001533322,0.0002445831,0.00010572828,0.00004549347,0.000008809961,0.000119763514,0.00021200649,0.000049859253],"category_scores_gemma":[0.00034909154,0.00014830143,0.00006752307,0.00011109149,0.000114109636,0.0000032899763,0.00011707894,0.00011833966,0.0000012272856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009307271,0.000018449424,0.00023618864,0.000015645854,0.000017999173,4.6522402e-7,0.000016031983,0.000067332556,0.9621448,0.009468354,0.000012023248,0.027909653],"study_design_scores_gemma":[0.00061165914,0.0004803938,0.00019755219,0.000023157296,0.00001649072,0.0000048707643,0.0000485162,0.0026503426,0.9760104,0.009533923,0.010223106,0.00019961134],"about_ca_topic_score_codex":0.000066234556,"about_ca_topic_score_gemma":0.0000038946255,"teacher_disagreement_score":0.10574139,"about_ca_system_score_codex":0.000011634464,"about_ca_system_score_gemma":0.000015711694,"threshold_uncertainty_score":0.6047557},"labels":[],"label_agreement":null},{"id":"W2405878733","doi":"10.1385/1-59259-087-x:297","title":"Assays for Radiolabel-Photoaffinity Labeling of Angiotensin Receptors","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Fleurimont","funders":"","keywords":"Photoaffinity labeling; Receptor; Chemistry; Affinity label; Ligand (biochemistry); Biochemistry; Affinity labeling; Covalent bond; Enzyme; Combinatorial chemistry; Diazirine; Substrate specificity; Stereochemistry; Organic chemistry","score_opus":0.045201010425628206,"score_gpt":0.2684781287935178,"score_spread":0.22327711836788958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2405878733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87965775,0.0145995375,0.05257487,0.000017881235,0.0020458368,0.0020123182,0.00010432582,0.000094477575,0.048892982],"genre_scores_gemma":[0.97212917,0.00018983075,0.02348887,0.00013414674,0.00024220353,0.000069631504,0.00006279171,0.00006515702,0.0036182236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990205,0.000078244615,0.00025578967,0.0002932275,0.00010614068,0.00024610278],"domain_scores_gemma":[0.9993491,0.000024488316,0.00012541593,0.0002982592,0.00013882582,0.00006390017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037186735,0.0001522242,0.00020169845,0.00003264287,0.00010428743,0.000018488112,0.0001457275,0.0001603923,0.000033094922],"category_scores_gemma":[0.00012087455,0.00015007652,0.00014704908,0.000012202265,0.000046503046,0.0000021294618,0.00003469471,0.000066966895,6.672596e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049596325,0.000028763667,0.000009921421,0.0000354643,0.00008307226,5.7350417e-7,0.000101836165,0.00006442915,0.98196274,0.010411783,0.00210076,0.0051510516],"study_design_scores_gemma":[0.00049070973,0.00017113438,0.0000024228925,0.000018078728,0.000026902402,0.0000024672677,0.000027360633,0.000043346874,0.83625036,0.0004233755,0.1623876,0.0001562542],"about_ca_topic_score_codex":0.000029918629,"about_ca_topic_score_gemma":0.000010717374,"teacher_disagreement_score":0.16028683,"about_ca_system_score_codex":0.00000805294,"about_ca_system_score_gemma":0.000037991937,"threshold_uncertainty_score":0.61199427},"labels":[],"label_agreement":null},{"id":"W2406525517","doi":"10.1124/mol.115.098509","title":"PDZ Protein Regulation of G Protein–Coupled Receptor Trafficking and Signaling Pathways","year":2015,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Canadian Institutes of Health Research","keywords":"PDZ domain; Postsynaptic density; Guanylate kinase; Cell biology; G protein-coupled receptor; Scaffold protein; Biology; Protein kinase A; Membrane protein; Transport protein; Signal transduction; Biochemistry; Receptor; Kinase; Postsynaptic potential","score_opus":0.032189803456919325,"score_gpt":0.3044668203002467,"score_spread":0.2722770168433274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2406525517","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.029093921,0.9642263,0.0036141197,0.000014287369,0.00037737115,0.0025222427,0.000039937306,0.000032428296,0.00007937735],"genre_scores_gemma":[0.022033101,0.966541,0.0071302126,0.00009026829,0.0012106256,0.001153205,0.001139816,0.0003215277,0.0003802635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99705464,0.0005884025,0.00082569715,0.00080998056,0.00028281458,0.00043846772],"domain_scores_gemma":[0.998513,0.0000167808,0.00070963585,0.00033221117,0.00023771958,0.00019069108],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008176571,0.00055949425,0.0012898326,0.0001868304,0.000083234714,0.00002834116,0.0003330508,0.000781574,0.00023151611],"category_scores_gemma":[0.00006370938,0.0005315718,0.00037496822,0.00021295137,0.00012075289,0.0000067198357,0.00022177177,0.00034254324,0.000009808503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044510187,0.00005549789,6.900813e-8,0.0026575837,0.0002609807,0.000010533593,0.000029849698,0.000048861857,0.87357706,0.00012936551,0.00013262601,0.123053074],"study_design_scores_gemma":[0.00057773245,0.00038767638,2.984728e-8,0.0011611306,0.00037668267,0.000025037272,0.000014007109,0.000100319194,0.5075319,0.00006258675,0.4893115,0.00045145076],"about_ca_topic_score_codex":0.000005274105,"about_ca_topic_score_gemma":5.151659e-7,"teacher_disagreement_score":0.48917887,"about_ca_system_score_codex":0.000055483288,"about_ca_system_score_gemma":0.0004448956,"threshold_uncertainty_score":0.9997136},"labels":[],"label_agreement":null},{"id":"W2407275034","doi":"10.1016/bs.pmbts.2015.02.012","title":"Regulation of GPCR Anterograde Trafficking by Molecular Chaperones and Motifs","year":2015,"lang":"en","type":"review","venue":"Progress in molecular biology and translational science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"G protein-coupled receptor; Cell biology; Endoplasmic reticulum; Golgi apparatus; Endocytic cycle; Biology; Receptor; Signal transduction; Endocytosis; Biochemistry","score_opus":0.01798412718144913,"score_gpt":0.3387555750169002,"score_spread":0.32077144783545103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2407275034","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.022829415,0.969558,0.007083848,0.00002918117,0.00006376329,0.00036344503,0.000037956208,0.0000062565005,0.000028153063],"genre_scores_gemma":[0.3118194,0.6823899,0.0053322874,0.000015209965,0.000029205941,0.000054932596,0.00032966395,0.00002562741,0.0000037696961],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998297,0.00014490672,0.00041119123,0.0006618287,0.00020599333,0.000279089],"domain_scores_gemma":[0.99943185,0.000016008982,0.00019430259,0.00016809734,0.00009282694,0.00009690979],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072864385,0.00026578637,0.00052141555,0.00018002653,0.00007631207,0.00003134914,0.00024734074,0.0003431099,0.000004259316],"category_scores_gemma":[0.00002255094,0.00023005475,0.000092088216,0.00029991378,0.00096747174,0.000012765126,0.00008031388,0.00013933146,2.3348359e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018322793,0.00006293434,0.00061167387,0.0006994882,0.00005852135,0.0000038538838,0.00006364524,0.000015463916,0.092239074,0.005308288,0.0000021295086,0.90091664],"study_design_scores_gemma":[0.0061449427,0.0046621547,0.0014364971,0.011906171,0.0014240439,0.0007936459,0.00018618433,0.0034716222,0.2267326,0.02393688,0.7132897,0.0060155806],"about_ca_topic_score_codex":0.0000029613288,"about_ca_topic_score_gemma":0.0000014793644,"teacher_disagreement_score":0.89490104,"about_ca_system_score_codex":0.000007944851,"about_ca_system_score_gemma":0.00016403243,"threshold_uncertainty_score":0.93813604},"labels":[],"label_agreement":null},{"id":"W2407589310","doi":"10.1007/978-1-61779-160-4_22","title":"Tandem Affinity Purification and Identification of Heterotrimeric G Protein-Associated Proteins","year":2011,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Heterotrimeric G protein; G protein-coupled receptor; G protein; GTPase-activating protein; Cell biology; G beta-gamma complex; Effector; Biology; Gq alpha subunit; Chemistry; Signal transduction; Biochemistry","score_opus":0.03216474117281629,"score_gpt":0.3374844910139299,"score_spread":0.3053197498411136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2407589310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5031966,0.00033680798,0.4959628,0.000007724884,0.000043558284,0.00033446206,0.0000032745638,0.0000061517085,0.00010863454],"genre_scores_gemma":[0.68326116,0.000037810034,0.3164907,0.000022130842,0.0000103572065,0.00010126506,0.000030965453,0.000013349246,0.000032225653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998121,0.00086666783,0.00040770686,0.0003675124,0.000052859144,0.00018421854],"domain_scores_gemma":[0.9993167,0.0000129272485,0.00026718294,0.0002783654,0.00008607203,0.000038762286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013972584,0.00013157091,0.00021124621,0.000095261836,0.000033736353,0.000005989271,0.00015766063,0.00022648448,0.000020257667],"category_scores_gemma":[0.0005017545,0.00012891667,0.000060419614,0.00016241029,0.00010712618,0.0000032755022,0.000074498195,0.00009767871,7.927936e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029602925,0.000082305305,0.0014374666,0.000011305246,0.000029113806,9.124694e-7,0.00007164693,0.0000023214184,0.99215895,0.0013763546,7.958499e-7,0.0047992077],"study_design_scores_gemma":[0.00028557907,0.000311989,0.0021535826,0.000011197178,0.00001093798,0.000002892953,0.000030965348,0.00006525103,0.99129647,0.0056107542,0.00008902245,0.00013135307],"about_ca_topic_score_codex":0.000045031786,"about_ca_topic_score_gemma":0.000006068036,"teacher_disagreement_score":0.18006459,"about_ca_system_score_codex":0.0000117329355,"about_ca_system_score_gemma":0.000032699998,"threshold_uncertainty_score":0.5257069},"labels":[],"label_agreement":null},{"id":"W2408233902","doi":"10.1016/b978-0-444-63425-2.00008-8","title":"Dopamine receptor heteromeric complexes and their emerging functions","year":2014,"lang":"en","type":"review","venue":"Progress in brain research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Aging","keywords":"D2-like receptor; Dopamine; D1-like receptor; Dopamine receptor; Receptor; Neuroscience; Endogenous agonist; Dopamine receptor D3; Biology; Dopaminergic; Chemistry; Dopamine receptor D1; Biochemistry","score_opus":0.08217113573786956,"score_gpt":0.4119803051321701,"score_spread":0.32980916939430055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2408233902","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001053679,0.9974113,0.00027598417,0.00010749478,0.0001894728,0.0007528553,0.00003876538,0.000016168182,0.00015427209],"genre_scores_gemma":[0.0008719849,0.9960108,0.0004889928,0.0000193162,0.0005316416,0.00057062233,0.0005117571,0.00008703267,0.0009078664],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99685436,0.00095469726,0.00047482998,0.00078319304,0.00028154958,0.0006513548],"domain_scores_gemma":[0.9988869,0.00023802729,0.0001275719,0.00049639645,0.000109254965,0.00014189247],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0022029665,0.00035876286,0.0008541706,0.0003958292,0.00022472774,0.00012475958,0.00043675542,0.00036554414,0.0001476306],"category_scores_gemma":[0.00022256754,0.0002733353,0.00019778324,0.00046146585,0.00032886636,0.0000044522994,0.000528538,0.00065599155,0.00002692056],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011684201,0.000046698515,0.000038436978,0.0029732066,0.00007015669,0.0000020413872,0.000031086027,3.7711035e-7,0.0009428703,0.00006064738,0.0015090797,0.9943137],"study_design_scores_gemma":[0.00017435265,0.00027742184,0.0000032004882,0.0019721545,0.000010034226,0.00001876548,0.0000758793,0.00002494715,0.00035323997,0.00003815682,0.9967651,0.000286796],"about_ca_topic_score_codex":0.000009569066,"about_ca_topic_score_gemma":0.0000127104295,"teacher_disagreement_score":0.99525595,"about_ca_system_score_codex":0.00003952735,"about_ca_system_score_gemma":0.000112132395,"threshold_uncertainty_score":0.99997187},"labels":[],"label_agreement":null},{"id":"W2408701418","doi":"10.1007/978-1-61779-160-4_2","title":"Imaging-Based Approaches to Understanding G Protein-Coupled Receptor Signalling Complexes","year":2011,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Signalling; Förster resonance energy transfer; Signalling pathways; Computational biology; Receptor; Bimolecular fluorescence complementation; Chemistry; Cell biology; Biology; Biochemistry; Physics; Gene","score_opus":0.15367578993060182,"score_gpt":0.33997779379336207,"score_spread":0.18630200386276025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2408701418","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.053811383,0.00045312516,0.94413453,0.00015595017,0.00018212832,0.00059065776,0.000006555052,0.000031436623,0.0006342025],"genre_scores_gemma":[0.3635796,0.000002813296,0.63577235,0.0003600428,0.000051753672,0.00011647361,0.00004837199,0.0000423987,0.000026236377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99732375,0.0008319332,0.0004207902,0.0007692053,0.000096111784,0.00055823114],"domain_scores_gemma":[0.99925506,0.00003877692,0.00012323441,0.0004038905,0.000035012235,0.0001439957],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015662451,0.00031278914,0.00036043557,0.00022595997,0.000093342926,0.000024522644,0.00040449668,0.0002457407,0.0002095509],"category_scores_gemma":[0.00020918141,0.0003046882,0.00016029802,0.00026453103,0.0001207187,0.0000038067162,0.00016361558,0.00019316566,0.00000861459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014133309,0.00006772302,0.0004924379,0.000017437731,0.000035629786,0.0000067333276,0.0001109041,0.00031130685,0.98356247,0.013901201,0.000009356613,0.0013434661],"study_design_scores_gemma":[0.0004944873,0.00033708144,0.000015041552,0.000033742414,0.000011893278,0.000003686238,0.0001919525,0.0026816756,0.9812875,0.013795637,0.00074918283,0.00039815585],"about_ca_topic_score_codex":0.000059001308,"about_ca_topic_score_gemma":0.000014638698,"teacher_disagreement_score":0.3097682,"about_ca_system_score_codex":0.00006592795,"about_ca_system_score_gemma":0.00007770917,"threshold_uncertainty_score":0.9999405},"labels":[],"label_agreement":null},{"id":"W2409027788","doi":"10.1016/bs.mcb.2015.11.010","title":"Cellular and subcellular context determine outputs from signaling biosensors","year":2016,"lang":"en","type":"article","venue":"Methods in cell biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Biosensor; Biology; Context (archaeology); Software portability; Signal transduction; Computational biology; Cell biology; Biochemistry; Computer science","score_opus":0.026424250612137913,"score_gpt":0.3033842052035625,"score_spread":0.2769599545914246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2409027788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7518978,0.0039139003,0.24347506,0.000060316506,0.00032613968,0.00012087767,0.000021838749,0.000011541401,0.00017253868],"genre_scores_gemma":[0.8636718,0.0003939165,0.1351187,0.00018275605,0.00021604005,0.000013667937,0.0000377958,0.000029222874,0.00033609185],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978527,0.0006939216,0.0003717298,0.00065375835,0.00005127652,0.00037660776],"domain_scores_gemma":[0.9991434,0.00025957322,0.000121773024,0.000331914,0.000040148454,0.000103199396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00087410555,0.00024089437,0.00033891512,0.0000869823,0.00005232294,0.000013489974,0.00019971504,0.00039937795,0.00021502882],"category_scores_gemma":[0.0001689094,0.00017356592,0.00009098633,0.000066126515,0.00014221651,0.0000037298962,0.00015630703,0.00010304724,0.000012558407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005107045,0.000021872434,0.002164907,0.0000061358414,0.000017149325,0.000008128633,0.000047242887,0.0000017739405,0.90896374,0.000092053815,0.000011093374,0.08861486],"study_design_scores_gemma":[0.0008351432,0.00023826725,0.00003769056,0.000020354248,0.000013170345,0.0000024643828,0.00008769346,0.000084640254,0.97605217,0.0016038304,0.020757105,0.000267486],"about_ca_topic_score_codex":0.00008505392,"about_ca_topic_score_gemma":0.00001698433,"teacher_disagreement_score":0.11177402,"about_ca_system_score_codex":0.000014782773,"about_ca_system_score_gemma":0.000024818863,"threshold_uncertainty_score":0.70778126},"labels":[],"label_agreement":null},{"id":"W2410042075","doi":"10.1007/978-1-4939-1755-6_6","title":"Characterization of the Interaction Between the Prostaglandin D2 DP1 Receptor and the Intracellular l-Prostaglandin D Synthase","year":2014,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Immunoprecipitation; Prostaglandin E2 receptor; Intracellular; G protein-coupled receptor; Receptor; Prostaglandin; Endogeny; Recombinant DNA; Chemistry; Prostaglandin D2; Cell biology; Biochemistry; Biology; Gene","score_opus":0.01344278200297359,"score_gpt":0.30968625498329533,"score_spread":0.2962434729803217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410042075","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.57638973,0.00017012517,0.42224583,0.0005204837,0.00024655156,0.00036809655,0.000010613699,0.0000036673957,0.00004491255],"genre_scores_gemma":[0.97951245,0.00013327134,0.019576676,0.00030570992,0.0001891785,0.00007912237,0.00010890045,0.000023813978,0.00007088686],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99634194,0.0026742858,0.00036914757,0.00032288127,0.00008063241,0.00021108067],"domain_scores_gemma":[0.99901026,0.0002045431,0.00025820103,0.00044458892,0.000052509225,0.000029918336],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002862238,0.00016949896,0.000265166,0.000045550798,0.00012098796,0.000024928166,0.00031787626,0.00021687572,0.000022730657],"category_scores_gemma":[0.00071416446,0.00008490188,0.00010712956,0.0001612983,0.00032489715,0.000004142924,0.00021350537,0.00023308952,9.158583e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000108406944,0.000012918043,0.0035110048,0.0000121012745,0.000036760695,1.4299381e-7,0.00014874617,0.000009964241,0.98278946,0.0022253408,0.000004969985,0.01114021],"study_design_scores_gemma":[0.00072457263,0.00013743246,0.00061048975,0.000021720896,0.00003078715,0.0000054100265,0.00008351703,0.0004410654,0.98733765,0.001539939,0.008951791,0.00011560754],"about_ca_topic_score_codex":0.00003832792,"about_ca_topic_score_gemma":0.000005625581,"teacher_disagreement_score":0.40312272,"about_ca_system_score_codex":0.000012081091,"about_ca_system_score_gemma":0.00002176226,"threshold_uncertainty_score":0.34621984},"labels":[],"label_agreement":null},{"id":"W2410593210","doi":"10.1385/1-59259-684-3:391","title":"Patch-Clamp Recording Methods for Examining Adrenergic Regulation of Potassium Currents in Ocular Epithelial Cells","year":2003,"lang":"en","type":"review","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Intracellular; Ion channel; Cell biology; Patch clamp; Extracellular; Receptor; Signal transduction; Ligand-gated ion channel; Biophysics; Potassium channel; Chemistry; Biology; Biochemistry","score_opus":0.12759598173418943,"score_gpt":0.38640792576047706,"score_spread":0.2588119440262876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410593210","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016421302,0.96264154,0.034227353,1.4323093e-7,0.0008513407,0.0009909167,0.00005603368,0.000009637947,0.001058816],"genre_scores_gemma":[0.0002926642,0.9741054,0.022871042,0.000008301643,0.00037406827,0.00036629676,0.00040260164,0.0001253667,0.0014542646],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974337,0.0005750655,0.0008587993,0.0006494465,0.00013299841,0.0003499676],"domain_scores_gemma":[0.99865353,0.000064351945,0.00064865215,0.00048319797,0.00008444179,0.0000658414],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009579197,0.00041671118,0.0010787772,0.000148927,0.00007130189,0.00003236407,0.0003129371,0.00054554065,0.000022199803],"category_scores_gemma":[0.000046570844,0.00039576087,0.00043607914,0.00003193916,0.000039528208,0.0000036984827,0.00011303944,0.00019079288,5.0286786e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014725322,0.00002290466,1.4987968e-7,0.0035346628,0.000110847715,7.7042534e-7,0.000044206463,0.000035013843,0.035266448,0.0005880047,0.00005632654,0.96032596],"study_design_scores_gemma":[0.00039735332,0.0001429188,1.65778e-7,0.0020792978,0.00027819426,0.0000028142413,0.000009694853,0.00009576644,0.13977155,0.00026434814,0.8565414,0.0004164685],"about_ca_topic_score_codex":0.00004841616,"about_ca_topic_score_gemma":0.0000062916342,"teacher_disagreement_score":0.9599095,"about_ca_system_score_codex":0.000034942408,"about_ca_system_score_gemma":0.00009807811,"threshold_uncertainty_score":0.99984944},"labels":[],"label_agreement":null},{"id":"W2410919549","doi":"10.1016/j.bpj.2015.11.1198","title":"Single-Molecule Study of the Oligomeric States of the M2 Muscarinic Receptor, the Gi1 Protein and the M2-Gi1 Complex","year":2016,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Rhodopsin; Tetramer; Receptor; G protein; Biophysics; Population; Chemistry; Biology; Biochemistry","score_opus":0.01388236712069916,"score_gpt":0.22938595694874908,"score_spread":0.21550358982804993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410919549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976898,0.000129061,0.00032861228,0.0011284015,0.0001781177,0.00045694382,0.000011359113,0.0000024658973,0.00007524732],"genre_scores_gemma":[0.99930143,0.00006004738,0.000049257163,0.00011925187,0.00027003704,0.000014375208,8.456611e-7,0.000016374994,0.00016837688],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984716,0.00048687015,0.0003379444,0.00018320481,0.00031797806,0.00020240917],"domain_scores_gemma":[0.9989753,0.000065384724,0.0003602859,0.0004266535,0.00012380039,0.00004857054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038646153,0.00015537042,0.00021840553,0.000012768235,0.00027899683,0.000038846538,0.0006055817,0.000056571313,0.000046059453],"category_scores_gemma":[0.00008752642,0.000050177427,0.00022087354,0.0001347055,0.0004874645,0.000005299309,0.00031142955,0.00017524677,0.0000013875275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001356682,0.00020287151,0.00015340469,0.000005347956,0.0000996919,2.5304865e-7,0.0002580478,0.0000073402357,0.9959299,0.000334817,0.00016995019,0.0027026976],"study_design_scores_gemma":[0.0015547795,0.00069866347,0.0021403702,0.000054877983,0.00005493525,0.000013658211,0.00083140965,0.000038771042,0.9922022,0.00051456667,0.0017874242,0.00010833024],"about_ca_topic_score_codex":0.00003272144,"about_ca_topic_score_gemma":0.0000073748156,"teacher_disagreement_score":0.0037276964,"about_ca_system_score_codex":0.000011377656,"about_ca_system_score_gemma":0.00004587601,"threshold_uncertainty_score":0.21458463},"labels":[],"label_agreement":null},{"id":"W2413386661","doi":"10.1007/978-1-59745-205-2_6","title":"Pharmacogenomics of G Protein-Coupled Receptor","year":2008,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Pharmacogenomics; Pharmacology; Medicine; Computational biology; Biology","score_opus":0.04419383422615238,"score_gpt":0.42269668613660266,"score_spread":0.3785028519104503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2413386661","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001051254,0.7197795,0.2788395,0.000002745042,0.00030695336,0.0007919643,0.000037620037,0.000008480461,0.00012810681],"genre_scores_gemma":[0.0000015584673,0.6264672,0.37275144,0.000027905926,0.00011453065,0.00017408142,0.00028816238,0.00007507543,0.00010004355],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9955007,0.0019403192,0.0010981314,0.00087781774,0.00009587339,0.00048718907],"domain_scores_gemma":[0.9984467,0.00006780936,0.0006227078,0.0006764108,0.0000896302,0.00009676839],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009857164,0.00057957234,0.0018613684,0.00028631644,0.000039919534,0.00000705855,0.0006785232,0.0011518257,0.00013673773],"category_scores_gemma":[0.00032970952,0.00051940023,0.0008173555,0.00032412464,0.00018152781,0.0000015137609,0.0003219028,0.0004326908,0.000010198483],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015828045,0.00004179709,6.49847e-7,0.00071281707,0.00015331699,0.0000072138296,0.0000069331395,0.0000037023126,0.62404007,0.00020701445,0.000017290424,0.37479338],"study_design_scores_gemma":[0.00026605025,0.0002114947,1.942219e-8,0.0005076766,0.00007247536,0.000042263015,0.0000037611608,0.000010857171,0.27656382,0.00016904449,0.7217477,0.00040480183],"about_ca_topic_score_codex":0.000016900014,"about_ca_topic_score_gemma":0.0000011058241,"teacher_disagreement_score":0.7217304,"about_ca_system_score_codex":0.000047813228,"about_ca_system_score_gemma":0.0003647347,"threshold_uncertainty_score":0.99972576},"labels":[],"label_agreement":null},{"id":"W2415189901","doi":"10.1016/b978-0-12-417197-8.00007-9","title":"Constitutive Activities and Inverse Agonism in Dopamine Receptors","year":2014,"lang":"en","type":"review","venue":"Advances in pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; King Saud University","keywords":"G protein-coupled receptor; Receptor; Cell biology; Biology; Dopamine receptor; Intracellular; D1-like receptor; Inverse agonist; Dopamine receptor D2; Signal transduction; Biochemistry; Dopamine receptor D3; Agonist","score_opus":0.014934830664099242,"score_gpt":0.34459180592687016,"score_spread":0.32965697526277093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2415189901","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00096676324,0.99565804,0.000151949,0.00000877563,0.0016159265,0.0004478059,0.000017585,0.000007853122,0.0011252889],"genre_scores_gemma":[0.00084392296,0.99776673,0.0004073854,0.00014033949,0.0003205348,0.00018380057,0.00010181279,0.000030523886,0.00020492435],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998301,0.00032218386,0.00042572082,0.00055143854,0.00006470129,0.0003349223],"domain_scores_gemma":[0.9994506,0.0001124287,0.00022278038,0.00013146499,0.000016150774,0.00006657929],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029309109,0.0003436395,0.00096195575,0.00020061822,0.000038891463,0.0000098570945,0.00019518475,0.0003777876,0.00014164676],"category_scores_gemma":[0.000042980515,0.0003178675,0.00010680502,0.00013492987,0.00028424777,0.000013264359,0.00015960792,0.00035435212,0.000006303481],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053108593,0.00006411379,0.000029481247,0.0025502287,0.000079481775,0.00003636845,0.000046379533,0.00005538252,0.005029867,0.00037168057,0.0003928489,0.99129105],"study_design_scores_gemma":[0.0005665457,0.00014217339,2.1065158e-7,0.00063529453,0.000072475705,0.000031979882,0.0000453698,0.000009552664,0.0042517963,0.00009964893,0.993822,0.00032299312],"about_ca_topic_score_codex":0.000008374969,"about_ca_topic_score_gemma":0.00008940347,"teacher_disagreement_score":0.9934291,"about_ca_system_score_codex":0.000053705255,"about_ca_system_score_gemma":0.00013915247,"threshold_uncertainty_score":0.99992734},"labels":[],"label_agreement":null},{"id":"W2415495119","doi":"10.1007/978-1-62703-251-3_10","title":"Functional Analysis of Human D1 and D5 Dopaminergic G Protein-Coupled Receptors: Lessons from Mutagenesis of a Conserved Serine Residue in the Cytosolic End of Transmembrane Region 6","year":2012,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Adenylyl cyclase; Biology; HEK 293 cells; G protein; Receptor; Molecular biology; Biochemistry; Cell biology","score_opus":0.036922780966832505,"score_gpt":0.3497988693918441,"score_spread":0.31287608842501163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2415495119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85130525,0.0016705268,0.14663123,0.0000799262,0.00003938812,0.00022197138,0.000022244716,0.0000021240855,0.000027375545],"genre_scores_gemma":[0.9490892,0.000113000446,0.050456896,0.000039855717,0.000030519815,0.000050437357,0.00018939898,0.000014413223,0.000016227594],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99730116,0.0014751174,0.00057825906,0.00032046845,0.00009675911,0.00022824279],"domain_scores_gemma":[0.9991304,0.00012769597,0.00026893185,0.00036712296,0.00006725789,0.00003856416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015403745,0.00017670737,0.00057673367,0.00028090415,0.000024946607,0.0000029595544,0.00019824498,0.00027078346,0.00007303865],"category_scores_gemma":[0.00015233319,0.00014071765,0.00018946873,0.00052360416,0.00022295136,0.0000041072963,0.000061975385,0.00011215736,6.177062e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015899214,0.00012533837,0.008493856,0.00003890163,0.00032939398,0.0000020219004,0.00023491302,0.00015949967,0.98828346,0.0013370508,0.0000011341752,0.0008354728],"study_design_scores_gemma":[0.00067878165,0.00030917543,0.010437131,0.000023968807,0.0002028493,0.000004086523,0.00020967658,0.0001518173,0.987098,0.0007034754,0.00004872864,0.00013232528],"about_ca_topic_score_codex":0.00093096175,"about_ca_topic_score_gemma":0.00028556344,"teacher_disagreement_score":0.09778403,"about_ca_system_score_codex":0.000008231404,"about_ca_system_score_gemma":0.000034852765,"threshold_uncertainty_score":0.5738299},"labels":[],"label_agreement":null},{"id":"W2415875693","doi":"10.1021/bi501377b","title":"Comparative Mutagenesis Studies of Retinal Release in Light-Activated Zebrafish Rhodopsin Using Fluorescence Spectroscopy","year":2015,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Rhodopsin; Retinal; Schiff base; Biophysics; Chemistry; Retinaldehyde; Scotopic vision; Visual phototransduction; Transmembrane domain; Biology; Biochemistry; Stereochemistry; Membrane","score_opus":0.0633078237297562,"score_gpt":0.33104380098348946,"score_spread":0.26773597725373327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2415875693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99683076,0.0022786804,0.00026742808,0.000030144989,0.00010588297,0.00010710968,0.000012062242,0.000010460027,0.00035747138],"genre_scores_gemma":[0.9920373,0.000084071486,0.0075292843,0.000022434513,0.00015407059,0.0000075297917,0.000034738652,0.000017408123,0.000113192735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987903,0.00006777444,0.000322907,0.00038964747,0.00018319127,0.00024614783],"domain_scores_gemma":[0.99920094,0.000012550695,0.00017583393,0.0002874728,0.00020888717,0.00011431498],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024533417,0.00020230199,0.00032990478,0.00003876226,0.00003910701,0.000009585494,0.00018270117,0.00015764502,0.000017520906],"category_scores_gemma":[0.00018694674,0.00019806117,0.000073474126,0.00018136845,0.000103939165,0.0000055374758,0.0001093488,0.000099319186,0.0000017990596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024411942,0.00007528408,0.0005476481,0.000049480026,0.00005077927,0.000009025555,0.00022072619,0.0000897923,0.99797505,0.000004971149,0.00069927005,0.000033877473],"study_design_scores_gemma":[0.0005172259,0.0001404663,0.000051986495,0.00011289493,0.0000142800845,0.000012576824,0.0017853369,0.00019630119,0.9967697,0.000039946575,0.00014357216,0.00021567455],"about_ca_topic_score_codex":0.00003413954,"about_ca_topic_score_gemma":0.0000036724753,"teacher_disagreement_score":0.007261856,"about_ca_system_score_codex":0.00007047356,"about_ca_system_score_gemma":0.00018563084,"threshold_uncertainty_score":0.80767006},"labels":[],"label_agreement":null},{"id":"W2416037827","doi":"10.1007/978-1-59745-000-3_30","title":"Monitoring Protein Kinase A Activities Using Expressed Substrate in Live Cells","year":2006,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Protein kinase A; Epitope; Phosphorylation; Molecular biology; Kinase; Biochemistry; Biology; Intracellular; Chemistry; Antibody","score_opus":0.059065159349829865,"score_gpt":0.41325481902687927,"score_spread":0.3541896596770494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2416037827","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009185597,0.79318637,0.196245,0.0000011625968,0.00037412695,0.000906137,0.000027120752,0.000012798369,0.000061713574],"genre_scores_gemma":[0.00010059536,0.5446135,0.45446193,0.000008412324,0.00022089238,0.00032203662,0.00008916182,0.00010707758,0.00007638177],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99432516,0.0029244064,0.0008826731,0.0010623034,0.00010289992,0.0007025812],"domain_scores_gemma":[0.998786,0.00008628879,0.00041963806,0.0005955765,0.000037359623,0.000075140684],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0013250472,0.00067739177,0.001530737,0.00040252242,0.000050261755,0.00004210031,0.00048821286,0.0012971305,0.00002105016],"category_scores_gemma":[0.00011845219,0.00065022154,0.00046005344,0.0003242803,0.00011094517,0.000004865633,0.00026852798,0.00061649655,0.000002506818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013368111,0.000054134944,0.000009722074,0.0009634461,0.000048701746,0.000070411246,0.000016698485,0.000093439856,0.8399077,0.000033800414,9.654491e-7,0.15878761],"study_design_scores_gemma":[0.00031305858,0.00014449109,3.567802e-7,0.0028149225,0.00008071552,0.000014032207,0.000052645682,0.00003611857,0.92528814,0.00044483956,0.07008555,0.0007251612],"about_ca_topic_score_codex":0.00022615491,"about_ca_topic_score_gemma":0.00001646818,"teacher_disagreement_score":0.25821695,"about_ca_system_score_codex":0.00011600514,"about_ca_system_score_gemma":0.000264851,"threshold_uncertainty_score":0.9999994},"labels":[],"label_agreement":null},{"id":"W2416329088","doi":"10.1007/978-1-62703-251-3_8","title":"BRET Approaches to Characterize Dopamine and TAAR1 Receptor Pharmacology and Signaling","year":2012,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Dopamine; Dopamine receptor D2; Dopamine receptor; Receptor; Signal transduction; Dopamine receptor D3; Chemistry; Neuroscience; Pharmacology; Biology; Cell biology; Biochemistry","score_opus":0.06451727452727078,"score_gpt":0.3510678471900825,"score_spread":0.2865505726628117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2416329088","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5817938,0.0024053273,0.41494754,0.00021848228,0.0003114876,0.00022769356,0.000010239788,0.000009241897,0.00007621095],"genre_scores_gemma":[0.40032083,0.00019168276,0.5979493,0.0009777094,0.00030401285,0.0000897691,0.0000707934,0.00003513711,0.00006077436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99776417,0.00085583545,0.00029409287,0.0005154838,0.00004898495,0.0005214303],"domain_scores_gemma":[0.9994286,0.0000650115,0.00008072391,0.00018972252,0.00002285431,0.0002131207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015697515,0.00024554806,0.00033581269,0.0001286867,0.000058216177,0.00001693674,0.00014549833,0.00031048182,0.00008507156],"category_scores_gemma":[0.00015069619,0.00023251565,0.000051546416,0.00012711069,0.00011098395,0.000006167982,0.00028488203,0.0001677763,0.0000029630985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007291858,0.000040988863,0.0017659062,0.000017925318,0.000043701973,0.0000017038739,0.00012756808,0.0000065966838,0.97824115,0.0012879287,0.000023652496,0.018369952],"study_design_scores_gemma":[0.0004598079,0.0002977907,0.00032573316,0.000008595668,0.000021020482,0.000034578447,0.00007323229,0.00005588909,0.97805524,0.0003629965,0.020015175,0.00028993815],"about_ca_topic_score_codex":0.000011855097,"about_ca_topic_score_gemma":0.0000011926574,"teacher_disagreement_score":0.18300174,"about_ca_system_score_codex":0.000013175556,"about_ca_system_score_gemma":0.00001789446,"threshold_uncertainty_score":0.9481713},"labels":[],"label_agreement":null},{"id":"W2416337622","doi":"10.1073/pnas.1608061113","title":"Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling","year":2016,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institutes of Health; Austrian Science Fund; National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; Genome Canada","keywords":"G protein-coupled receptor; Cell biology; Scaffold protein; Receptor; Protein kinase A; Signal transduction; Intracellular; Cilium; Chemistry; Arrestin; Biology; Biophysics; Biochemistry; Kinase","score_opus":0.026025683591978693,"score_gpt":0.27842312185082696,"score_spread":0.25239743825884825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2416337622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985927,0.00032370133,0.000016334192,0.00034326114,0.000012821299,0.000057849593,0.000009338719,0.0000017433867,0.00064227683],"genre_scores_gemma":[0.9983688,0.0001040813,0.0013359678,0.00004491442,0.000073117226,0.00000236169,7.01063e-8,0.000002702482,0.00006800001],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992261,0.000003858736,0.00019591626,0.00016275022,0.00031921573,0.00009216426],"domain_scores_gemma":[0.9995229,0.00003601306,0.000244702,0.000005918077,0.0001686216,0.000021816935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006775312,0.000058475413,0.00009592732,0.000047819478,0.0000779472,0.000007570793,0.00026711982,0.00006177006,0.000013254377],"category_scores_gemma":[0.00026938794,0.00003277245,0.000040411214,0.00011961467,0.0004425189,0.000018243274,0.00010470987,0.00003256051,1.5514225e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008631717,0.0000068186437,0.0031551244,0.0000212957,0.000009732915,8.270589e-10,0.000036260906,0.000008150957,0.9901256,0.0061082803,0.000055379223,0.0004647481],"study_design_scores_gemma":[0.00011740508,0.00005507549,0.0012854608,0.00009398605,0.00000498301,0.0000023671605,0.00009058907,0.000025847945,0.9896115,0.008497838,0.0001675979,0.000047347465],"about_ca_topic_score_codex":0.0000015242786,"about_ca_topic_score_gemma":1.6460048e-8,"teacher_disagreement_score":0.002389558,"about_ca_system_score_codex":0.000003998759,"about_ca_system_score_gemma":0.0000178216,"threshold_uncertainty_score":0.16304792},"labels":[],"label_agreement":null},{"id":"W2417921410","doi":"10.1385/1-59259-087-x:305","title":"Radioligand Binding Assay","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Medical Research Council; Merck Canada","keywords":"Radioligand; Radioligand Assay; Receptor; Ligand binding assay; Agonist; Chemistry; Ligand (biochemistry); Biophysics; Centrifugation; Receptor–ligand kinetics; Dissociation constant; Molecular biology; Chromatography; Biochemistry; Biology","score_opus":0.03281169342689354,"score_gpt":0.254495778324852,"score_spread":0.22168408489795843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2417921410","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.62676984,0.0061856345,0.012142279,0.000005015449,0.000701714,0.00035000572,0.000010404656,0.000054017866,0.35378107],"genre_scores_gemma":[0.9860406,0.00011326964,0.0008544821,0.0000869408,0.00019004804,0.000021685544,0.000016814613,0.000029052231,0.012647092],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923486,0.00007410055,0.00013000987,0.00024902666,0.00009330894,0.00021867953],"domain_scores_gemma":[0.99961215,0.0000064463757,0.000047274625,0.00023989144,0.00002696994,0.000067250854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002467383,0.00011921328,0.00010294757,0.000024113177,0.00011661632,0.000041865365,0.00011954189,0.00010239481,0.00006648819],"category_scores_gemma":[0.00003156997,0.00011271406,0.000069975584,0.0000067299784,0.000028466951,0.0000014412268,0.000033709264,0.0000662722,0.000006489848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000102256745,0.0000117109985,0.000012713961,0.000011363691,0.00004725299,0.0000045511542,0.000074994874,0.000021229402,0.9713982,0.021825694,0.0018833651,0.004698733],"study_design_scores_gemma":[0.00020523774,0.00004355294,0.0000026754485,0.0000066406574,0.00000869332,0.0000074104555,0.000017098655,0.000009609943,0.69416416,0.00018197061,0.30523393,0.000119012526],"about_ca_topic_score_codex":0.000011414799,"about_ca_topic_score_gemma":0.000004198654,"teacher_disagreement_score":0.35927075,"about_ca_system_score_codex":0.0000062930662,"about_ca_system_score_gemma":0.000019201798,"threshold_uncertainty_score":0.4596346},"labels":[],"label_agreement":null},{"id":"W2418742902","doi":"10.1016/s0026-895x(24)26491-9","title":"The Guanine Nucleotide Exchange Factor RasGRP Is a High -Affinity Target for Diacylglycerol and Phorbol Esters","year":2000,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Protein kinase C; Diacylglycerol kinase; Chemistry; Phorbol; Guanine; Activator (genetics); Biochemistry; Receptor; Ligand (biochemistry); Nucleotide; Signal transduction; Gene","score_opus":0.0073673657391133485,"score_gpt":0.2559513224947824,"score_spread":0.24858395675566908,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2418742902","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921882,0.002174885,0.0030530554,0.0011245986,0.00044382346,0.0006816122,0.00010215035,0.000023291206,0.00020837528],"genre_scores_gemma":[0.99230736,0.0011621995,0.0012178129,0.0034512312,0.00034091418,0.00021413872,0.00007545467,0.000058327674,0.0011725783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984768,0.00014826747,0.00023874594,0.0004787627,0.0001137655,0.0005436697],"domain_scores_gemma":[0.99939644,0.000050524402,0.00007916407,0.00023939967,0.00006624972,0.00016823012],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024534826,0.00025104085,0.00022936038,0.000030501444,0.00028165587,0.000049947295,0.00026007052,0.00017372721,0.0018989631],"category_scores_gemma":[0.00002978137,0.00020554231,0.0001439026,0.000064541324,0.00011444097,0.0000057766297,0.00009383367,0.00012582855,0.000017279957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035836335,0.000047042024,0.000038101887,0.000018645556,0.00016617948,0.000009851138,0.00009272686,0.000046667185,0.9786043,0.000045274337,0.006846477,0.013726349],"study_design_scores_gemma":[0.0014372508,0.0004490972,0.000071109745,0.0000027733881,0.000051259256,0.000010004784,0.000019566713,0.0003034021,0.7745022,0.00022598826,0.22271709,0.00021023574],"about_ca_topic_score_codex":0.000022175329,"about_ca_topic_score_gemma":0.0000047486983,"teacher_disagreement_score":0.2158706,"about_ca_system_score_codex":0.000017151846,"about_ca_system_score_gemma":0.00004447255,"threshold_uncertainty_score":0.9990134},"labels":[],"label_agreement":null},{"id":"W2424323437","doi":"10.1385/1-59259-722-x:305","title":"Intracellular pH and pCa Measurement","year":2003,"lang":"en","type":"review","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Intracellular; Intracellular pH; Chemistry; Biophysics; Biochemistry; Biology","score_opus":0.11868273780167488,"score_gpt":0.2982674827991164,"score_spread":0.17958474499744154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2424323437","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000056217673,0.99086857,0.00083141867,3.7970221e-7,0.00021787817,0.000494108,0.000009439749,0.00001258696,0.0075599933],"genre_scores_gemma":[0.000050152834,0.9963727,0.0002163265,0.000028247425,0.0002764392,0.000110555826,0.00004984381,0.00006802119,0.0028276958],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984531,0.00015956716,0.0003544196,0.0005335671,0.00022910576,0.0002702481],"domain_scores_gemma":[0.9992521,0.0000047733824,0.00018304087,0.00038970102,0.00006751081,0.000102896134],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036974545,0.00037412977,0.00063427875,0.000041226416,0.000103884784,0.00006865414,0.0002110623,0.00036942327,0.000038283513],"category_scores_gemma":[0.000016176278,0.00032158653,0.00023212658,0.000007633556,0.00005067636,0.0000010493542,0.00012304414,0.00018750015,0.0000041922617],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000033139413,0.000015266622,1.2722398e-8,0.003050503,0.00024153726,0.000007181579,0.000017066479,3.9451277e-7,0.0021046235,0.002427934,0.00092618394,0.991206],"study_design_scores_gemma":[0.00012859044,0.00007222873,1.07022124e-8,0.001027788,0.0003026608,0.000018941815,0.0000029030862,0.000001209509,0.00729146,0.000030378153,0.99077106,0.00035279882],"about_ca_topic_score_codex":0.000010775107,"about_ca_topic_score_gemma":0.0000056230374,"teacher_disagreement_score":0.9908532,"about_ca_system_score_codex":0.000021697999,"about_ca_system_score_gemma":0.00007895176,"threshold_uncertainty_score":0.99992365},"labels":[],"label_agreement":null},{"id":"W2425110963","doi":"10.1007/s00210-016-1264-0","title":"Adenine attenuates the Ca2+ contraction-signaling pathway via adenine receptor-mediated signaling in rat vascular smooth muscle cells","year":2016,"lang":"en","type":"article","venue":"Naunyn-Schmiedeberg s Archives of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Vascular smooth muscle; Contraction (grammar); Cell biology; Signal transduction; Chemistry; Receptor; Smooth muscle; Muscle contraction; Pharmacology; Endocrinology; Biology; Biochemistry","score_opus":0.007758004749400853,"score_gpt":0.23455157829791717,"score_spread":0.22679357354851631,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2425110963","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9837896,0.002511694,0.010151705,0.0012467821,0.0012723061,0.0007024431,0.0000743209,0.00004194096,0.0002091764],"genre_scores_gemma":[0.99567604,0.0011191822,0.0013403087,0.00049716496,0.0007467265,0.00012232774,0.00010587788,0.00007559589,0.00031677718],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99676937,0.00063370547,0.00083025795,0.000734979,0.0002949828,0.0007366968],"domain_scores_gemma":[0.9982248,0.00070796476,0.0004256566,0.00034963246,0.00012572754,0.0001662273],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006511093,0.00043280676,0.0005439677,0.00021676459,0.00019157246,0.000022423505,0.0006062711,0.00028235375,0.00084016204],"category_scores_gemma":[0.000119599856,0.000295517,0.00033378316,0.00023914022,0.00031870324,0.000023743769,0.00020021279,0.00036654377,0.000021357888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004574004,0.00016629053,0.00015989934,0.00003200991,0.00020005315,0.000013156152,0.00021952749,0.0009786622,0.9865892,0.000042610536,0.0007930567,0.010348164],"study_design_scores_gemma":[0.0028536746,0.00036217915,0.000088254856,0.00008187379,0.000059586087,0.000003794934,0.000110417604,0.00040856173,0.9456698,0.00011942985,0.049863037,0.00037940187],"about_ca_topic_score_codex":0.00009939491,"about_ca_topic_score_gemma":0.000048540765,"teacher_disagreement_score":0.04906998,"about_ca_system_score_codex":0.000035350044,"about_ca_system_score_gemma":0.00016944048,"threshold_uncertainty_score":0.9999497},"labels":[],"label_agreement":null},{"id":"W2440039868","doi":"10.1093/neuonc/now080.20","title":"PCM-20PRE-CLINICAL DRUG SCREEN IN A PDX ETMR MOUSE MODEL","year":2016,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Drug; Chemistry; Pharmacology; Medicine","score_opus":0.02893391120150003,"score_gpt":0.3156152104725266,"score_spread":0.2866812992710266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2440039868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865318,0.0001398043,0.008503894,0.0014165549,0.0004092914,0.00025283563,0.00003038801,0.000029562365,0.0026858929],"genre_scores_gemma":[0.99177253,0.00063555315,0.0025958403,0.0026602282,0.00045411932,0.000041319025,0.000021263832,0.00004925121,0.001769902],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979989,0.00032623258,0.0004984356,0.00062333996,0.00012913827,0.00042398434],"domain_scores_gemma":[0.99906975,0.00013893595,0.000134277,0.00042578828,0.00006242897,0.00016880143],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059085735,0.00019890252,0.0003420888,0.00006725232,0.00004683828,0.000011564762,0.00034220025,0.00041117883,0.00015982894],"category_scores_gemma":[0.0003089714,0.00015095563,0.00015785276,0.00006589797,0.00011247817,0.0000068680633,0.00023029007,0.00022687345,0.000076476754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021539256,0.00014285107,0.0009791411,0.000003074549,0.000016356946,0.000018003677,0.00003861377,0.0001454753,0.9769739,0.0002390198,0.0061235954,0.015104609],"study_design_scores_gemma":[0.0028597352,0.001098468,0.00010258165,0.000013771074,0.000018257295,0.000022350498,0.000038044156,0.0016984971,0.8428536,0.0007537183,0.15020332,0.00033768557],"about_ca_topic_score_codex":0.000027538585,"about_ca_topic_score_gemma":0.0001557467,"teacher_disagreement_score":0.14407972,"about_ca_system_score_codex":0.000041049774,"about_ca_system_score_gemma":0.0002475184,"threshold_uncertainty_score":0.6155792},"labels":[],"label_agreement":null},{"id":"W2441148870","doi":"10.1007/978-1-61779-160-4_7","title":"Using BRET to Detect Ligand-Specific Conformational Changes in Preformed Signalling Complexes","year":2011,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Heterotrimeric G protein; Receptor; G protein-coupled receptor; Chemistry; Cell biology; Signalling; Effector; Ligand (biochemistry); G protein; Biophysics; Biology; Biochemistry","score_opus":0.08308864452948665,"score_gpt":0.37160338839166873,"score_spread":0.28851474386218207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2441148870","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.33911842,0.0004225324,0.65977854,0.000016561187,0.00014035216,0.00022718539,0.000007007296,0.000007815873,0.0002815641],"genre_scores_gemma":[0.26859316,0.00006539798,0.7308024,0.000357464,0.000060793504,0.000044187535,0.000041826544,0.000023664852,0.000011091614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99821126,0.00047341906,0.00038729518,0.00042317735,0.000077238234,0.00042760844],"domain_scores_gemma":[0.99949205,0.000033309247,0.00009957128,0.00023238652,0.000059943057,0.00008275778],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011770738,0.00021483732,0.00030287445,0.0002647718,0.00004660478,0.000014090201,0.0002772243,0.0002804001,0.00010197733],"category_scores_gemma":[0.00010955601,0.00020488718,0.000074992444,0.00023319188,0.0000634136,0.000004539888,0.00015931414,0.0001550076,0.0000039116658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009385987,0.000019473224,0.00033695882,0.000009814121,0.000018102606,0.000006410331,0.0002600457,0.00030089673,0.990992,0.001438797,0.0000035260825,0.006520131],"study_design_scores_gemma":[0.00040926848,0.0003025332,0.00017756628,0.000028908718,0.000004449176,0.000017209091,0.000105662104,0.00043558437,0.9914709,0.0048514344,0.0019348668,0.00026163206],"about_ca_topic_score_codex":0.00006941494,"about_ca_topic_score_gemma":0.000091469155,"teacher_disagreement_score":0.07102385,"about_ca_system_score_codex":0.000038297258,"about_ca_system_score_gemma":0.000045718563,"threshold_uncertainty_score":0.8355057},"labels":[],"label_agreement":null},{"id":"W2443205705","doi":"10.1007/978-1-4939-2336-6_9","title":"Quantifying GPCR Internalization: A Focus on the Kisspeptin Receptor","year":2015,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Children’s Health Research Institute; Western University","funders":"","keywords":"Internalization; G protein-coupled receptor; Receptor; Cell biology; HEK 293 cells; Biology; Signal transduction; Biochemistry","score_opus":0.07885364537945097,"score_gpt":0.40479830378054393,"score_spread":0.325944658401093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2443205705","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09353552,0.00095230126,0.90231013,0.0006628531,0.0005459591,0.00022413398,0.00000398905,0.000015817028,0.0017493019],"genre_scores_gemma":[0.4603772,0.00011136056,0.5368468,0.0019258071,0.00029766106,0.000098246324,0.00007901303,0.000058742422,0.0002051324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972991,0.0015169972,0.00031428755,0.00045681078,0.00010130175,0.0003115402],"domain_scores_gemma":[0.9991841,0.00008183124,0.00011311716,0.0004474864,0.00008658718,0.000086915905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021332772,0.00020345645,0.00021844223,0.00008646274,0.000051325736,0.000027155545,0.00038796262,0.00025636033,0.00012348808],"category_scores_gemma":[0.00101876,0.0001473153,0.00011358219,0.00019479216,0.00008809319,0.0000025494273,0.00016841768,0.00020342781,0.000022107928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071732014,0.000036724916,0.000532872,0.0000027293747,0.000030035828,0.000004518875,0.00010059583,0.00012986778,0.9635462,0.02943872,0.0002958198,0.005810188],"study_design_scores_gemma":[0.00038208574,0.00049994653,0.000009593085,0.000021706872,0.0000065067493,0.000010278273,0.00022893236,0.00026784133,0.95729387,0.0075294813,0.03354738,0.00020236091],"about_ca_topic_score_codex":0.00004028177,"about_ca_topic_score_gemma":0.000013882877,"teacher_disagreement_score":0.36684167,"about_ca_system_score_codex":0.000029996125,"about_ca_system_score_gemma":0.00005916178,"threshold_uncertainty_score":0.6007343},"labels":[],"label_agreement":null},{"id":"W2463376118","doi":"10.1016/b978-0-12-394587-7.00010-5","title":"Fine-Tuning of GPCR Signals by Intracellular G Protein Modulators","year":2013,"lang":"en","type":"review","venue":"Progress in molecular biology and translational science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health; Western University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Heterotrimeric G protein; G protein; Regulator of G protein signaling; GTPase-activating protein; Effector; Cell biology; GTPase; Signal transduction; G beta-gamma complex; Intracellular; Biology; Small GTPase; Chemistry","score_opus":0.015729620407357984,"score_gpt":0.31886830643115055,"score_spread":0.30313868602379257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2463376118","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01318482,0.97245497,0.013462396,0.000022273936,0.000055011526,0.00073834363,0.000040807376,0.000005708515,0.00003565642],"genre_scores_gemma":[0.16623653,0.8149851,0.017516714,0.0000233023,0.00008097343,0.00046421422,0.00059721456,0.000057193643,0.000038774924],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980569,0.0001700358,0.000522424,0.00069277064,0.00020552249,0.00035237332],"domain_scores_gemma":[0.99932194,0.000020656407,0.00025093157,0.000218289,0.00009300059,0.00009520626],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007054889,0.00030129348,0.0005831979,0.00018415862,0.00009509915,0.000029715406,0.00041932974,0.0004180873,0.00004007367],"category_scores_gemma":[0.000032774293,0.0002494461,0.00014398278,0.0003615829,0.0008732954,0.000011083181,0.000093602175,0.00021273094,0.0000016190736],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008906671,0.000066974375,0.00029521217,0.00089293165,0.00006603236,0.0000034332402,0.000018524008,0.000014612376,0.39289486,0.0050681788,0.000005100574,0.6006652],"study_design_scores_gemma":[0.001163042,0.00092648197,0.00003586243,0.005267152,0.00026158494,0.00006612326,0.000022983673,0.00084451097,0.64462346,0.008847891,0.33585584,0.0020850927],"about_ca_topic_score_codex":0.000007347224,"about_ca_topic_score_gemma":0.000001215778,"teacher_disagreement_score":0.5985801,"about_ca_system_score_codex":0.00000765938,"about_ca_system_score_gemma":0.0002403075,"threshold_uncertainty_score":0.99999577},"labels":[],"label_agreement":null},{"id":"W2463409931","doi":"10.1385/0-89603-488-7:107","title":"Selective Antagonism of Receptor Signaling Using Antisense RNA to Deplete G-Protein Subunits","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Medical Research Council","keywords":"Receptor; Biology; 5-HT5A receptor; Signal transduction; G protein-coupled receptor; Cell biology; Rhodopsin-like receptors; Biochemistry; Metabotropic receptor; Agonist","score_opus":0.04570866559543548,"score_gpt":0.2710085524363838,"score_spread":0.2252998868409483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2463409931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9834874,0.0008898681,0.011042512,0.0000019006952,0.00016953106,0.00044515237,0.000021455768,0.000018017052,0.0039241486],"genre_scores_gemma":[0.99113804,0.000022264276,0.0078114844,0.00006771354,0.00013618432,0.00002196115,0.000013967682,0.000050387378,0.0007380207],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985918,0.00016344177,0.00031239985,0.00040868542,0.00018106244,0.00034261864],"domain_scores_gemma":[0.99921435,0.000010390421,0.00014979718,0.00031728006,0.00018555284,0.00012261322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027523612,0.00021457978,0.00024355143,0.000072421506,0.000154884,0.0000327269,0.00017211524,0.00015292884,0.000036287467],"category_scores_gemma":[0.00007144121,0.00022416328,0.000106802036,0.000037201185,0.000046867593,0.0000040901414,0.00007304672,0.00011073379,0.0000023039659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060393006,0.000019425457,0.000003839588,0.000030491214,0.000066798006,0.0000028748163,0.00023551736,0.00029527926,0.99571526,0.0021710338,0.00006683038,0.0013322366],"study_design_scores_gemma":[0.00035617297,0.00023758833,0.0000024552762,0.00005815411,0.00002291782,0.000005051596,0.00006851421,0.000053934484,0.98951334,0.00015063901,0.009262177,0.0002690561],"about_ca_topic_score_codex":0.00011775794,"about_ca_topic_score_gemma":0.000009631688,"teacher_disagreement_score":0.009195347,"about_ca_system_score_codex":0.00001882006,"about_ca_system_score_gemma":0.0000700839,"threshold_uncertainty_score":0.91411126},"labels":[],"label_agreement":null},{"id":"W2465621312","doi":"10.1016/bs.mcb.2015.11.011","title":"Tracking GPCR biosynthesis and degradation using a nonradioactive pulse chase methodology","year":2016,"lang":"en","type":"article","venue":"Methods in cell biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Biology; G protein-coupled receptor; Receptor; Cell biology; Heterologous; Signal transduction; Heterologous expression; Translation (biology); Computational biology; Messenger RNA; Gene; Genetics; Recombinant DNA","score_opus":0.10782554446373795,"score_gpt":0.39493481745251413,"score_spread":0.2871092729887762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2465621312","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4359709,0.0006949361,0.56283855,0.00007050014,0.00018473288,0.00010508252,0.000008052471,0.0000065569047,0.000120651035],"genre_scores_gemma":[0.40760195,0.0003652405,0.59170145,0.00010383163,0.00011089957,0.000014789947,0.000008881275,0.000020752115,0.00007220018],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99688655,0.0018699459,0.00029910155,0.000563801,0.00003752111,0.0003430672],"domain_scores_gemma":[0.99905425,0.00045029825,0.00014138117,0.00023644036,0.000047642596,0.00006998469],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021913855,0.00019620964,0.00031661193,0.00014807995,0.000067615016,0.000010659444,0.00013635133,0.00038332428,0.00010811682],"category_scores_gemma":[0.0006690386,0.00014313226,0.000073327334,0.0001059986,0.00013756195,0.0000076186525,0.00009933574,0.00009455595,0.0000016413675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006973658,0.000022602631,0.00070841605,0.000006822,0.000018075196,0.0000017895707,0.00004743567,0.0000061328305,0.77956796,0.000121812,0.000001982894,0.21942726],"study_design_scores_gemma":[0.00050804974,0.00020750788,0.00014777454,0.0000160694,0.000020994157,0.000021151593,0.00009154178,0.00026623765,0.99408364,0.0022041153,0.0022214886,0.00021140314],"about_ca_topic_score_codex":0.00007058029,"about_ca_topic_score_gemma":0.000018750914,"teacher_disagreement_score":0.21921586,"about_ca_system_score_codex":0.00003231009,"about_ca_system_score_gemma":0.000041621013,"threshold_uncertainty_score":0.5836764},"labels":[],"label_agreement":null},{"id":"W2469309996","doi":"10.1038/ncomms12178","title":"Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":350,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; McGill University; Université de Montréal; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs; McGill University Health Centre; Réseau Québécois de Recherche sur les Médicaments","keywords":"G protein-coupled receptor; Endosome; Cell biology; Arrestin; Endocytosis; Receptor; Live cell imaging; Chemistry; Intracellular; Förster resonance energy transfer; Bioluminescence; Protein–protein interaction; Biology; Cell; Signal transduction; Fluorescence; Biochemistry","score_opus":0.01815792853188495,"score_gpt":0.28318457840669126,"score_spread":0.2650266498748063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2469309996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897663,0.005582679,0.0039365073,0.0001946755,0.00014729318,0.00027676942,0.000009229707,0.00001629888,0.00007021859],"genre_scores_gemma":[0.9818647,0.00093365344,0.016926477,0.000030920724,0.000105143205,0.0000346615,0.00001235853,0.000021461341,0.000070640155],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920714,0.00009717491,0.00018823592,0.0002365133,0.00008797015,0.00018295886],"domain_scores_gemma":[0.99912053,0.000051347448,0.000086099586,0.000597852,0.00009105893,0.000053085445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021903458,0.00012455463,0.0001199161,0.00004935657,0.00014515138,0.000026838954,0.0003379454,0.0002902277,0.000022355003],"category_scores_gemma":[0.00010439037,0.00010115392,0.0000341144,0.00009239908,0.0000624502,0.000009373661,0.00019276225,0.00026070702,0.0000029038245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019191657,0.000025903002,0.0002754671,0.000005102836,0.000011766206,2.1111892e-7,0.00012751922,0.000016075332,0.9973359,0.00012261806,0.000018581028,0.0020416363],"study_design_scores_gemma":[0.0004302608,0.00004079526,0.00020092273,0.00020455514,0.000006902936,0.0000018457348,0.00019878302,0.0002661623,0.9966912,0.000060656126,0.0017276385,0.00017025668],"about_ca_topic_score_codex":0.000017384842,"about_ca_topic_score_gemma":0.00007045083,"teacher_disagreement_score":0.012989969,"about_ca_system_score_codex":0.000036377893,"about_ca_system_score_gemma":0.000050126302,"threshold_uncertainty_score":0.4124937},"labels":[],"label_agreement":null},{"id":"W2471321162","doi":"10.1007/978-1-4939-2914-6_4","title":"Nuts and Bolts of CF3 and CH3 NMR Toward the Understanding of Conformational Exchange of GPCRs","year":2015,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Process Research Ortech (Canada); University of Toronto","funders":"","keywords":"Nuts and bolts; G protein-coupled receptor; Chemistry; Engineering; Structural engineering; Biochemistry; Receptor","score_opus":0.13231987186806846,"score_gpt":0.4372882372156035,"score_spread":0.304968365347535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2471321162","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00030501388,0.7516788,0.24739073,0.000011425189,0.00008388559,0.00029975566,0.000051130228,0.0000013182522,0.0001779123],"genre_scores_gemma":[0.0009167719,0.9150842,0.08377044,0.000024173167,0.000032015956,0.000025376621,0.00011330687,0.000022311582,0.000011423514],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978954,0.00092017825,0.0006480845,0.0002733393,0.00009094131,0.00017204424],"domain_scores_gemma":[0.99895215,0.00012799629,0.0005394059,0.00025325938,0.00008312731,0.000044033506],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020293132,0.00022802028,0.0010094038,0.00014206667,0.000017418839,0.000004563813,0.0002128375,0.000465471,0.000012888565],"category_scores_gemma":[0.00022931612,0.00015986628,0.00015789966,0.00013003648,0.00033208786,0.00000227131,0.00024759633,0.00014758654,8.083304e-8],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006543315,0.000050789142,0.00003862828,0.010264242,0.00053852703,0.0000029307046,0.00067173655,0.0000088616,0.2783706,0.019827755,0.000044528308,0.690116],"study_design_scores_gemma":[0.0020919384,0.0020208096,0.000009831358,0.0042536515,0.00090462767,0.00018529192,0.0015330655,0.0001786868,0.24646236,0.026954038,0.7142185,0.0011871959],"about_ca_topic_score_codex":0.00001715753,"about_ca_topic_score_gemma":0.0000023354644,"teacher_disagreement_score":0.714174,"about_ca_system_score_codex":0.000018083592,"about_ca_system_score_gemma":0.00013173072,"threshold_uncertainty_score":0.6519158},"labels":[],"label_agreement":null},{"id":"W2471992026","doi":"10.1038/nature18636","title":"Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation","year":2016,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":328,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; American Heart Association; National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Ministero della Salute; Howard Hughes Medical Institute","keywords":"Allosteric regulation; G protein-coupled receptor; Receptor; Extracellular; Chemistry; Biophysics; Intracellular; Ligand (biochemistry); Allosteric enzyme; Conformational change; Plasma protein binding; Agonist; Cell biology; Biochemistry; Biology","score_opus":0.005478034752557999,"score_gpt":0.22194021540694756,"score_spread":0.21646218065438955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2471992026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926989,0.000625663,0.005408235,0.0008013961,0.00016444526,0.00022248669,0.000021709104,0.000007696385,0.00004947344],"genre_scores_gemma":[0.9973205,0.00016660131,0.0012495227,0.00020262542,0.00006593414,0.000014046568,0.00001727023,0.000012792016,0.0009507242],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994108,0.000041468706,0.00010814948,0.00019786073,0.00012224665,0.00011945117],"domain_scores_gemma":[0.99961144,0.000015040566,0.00009291976,0.00017739894,0.0000761836,0.000027021773],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015906134,0.0001053045,0.000103465405,0.00002144863,0.00007251827,0.000009172201,0.00012212466,0.00048450648,0.000074697215],"category_scores_gemma":[0.000076246724,0.000056927474,0.000051866533,0.00004438292,0.00004461853,0.0000060924585,0.00008288551,0.0001676261,0.0000024184692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000960049,0.000008031902,0.000021766027,0.000012488391,0.000026396254,1.6928308e-7,0.000034659453,3.5365704e-7,0.9951983,0.00059405225,0.0002061166,0.0038016613],"study_design_scores_gemma":[0.0004430398,0.00015800129,0.00023410715,0.000052580894,0.000010658286,0.0000016780818,0.00011077816,0.000013507645,0.9957694,0.0012069232,0.001898528,0.00010078771],"about_ca_topic_score_codex":0.0000052478817,"about_ca_topic_score_gemma":0.000005788304,"teacher_disagreement_score":0.004621588,"about_ca_system_score_codex":0.00001002798,"about_ca_system_score_gemma":0.000016379583,"threshold_uncertainty_score":0.37369576},"labels":[],"label_agreement":null},{"id":"W2477184618","doi":"10.1385/0-89603-076-8:373","title":"Autoradiographic Methods for the Localization of Amine Receptor Sites in Neural Tissue","year":2003,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Receptor; Neurotransmitter receptor; Ligand (biochemistry); Neurotransmitter; Biochemistry; Chemistry; Membrane; In vitro; Biology; Biophysics; Cell biology","score_opus":0.05348002975734212,"score_gpt":0.3228326800310231,"score_spread":0.269352650273681,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2477184618","genre_codex":"methods","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006077863,0.19769746,0.6507862,0.000051827094,0.0025860062,0.0052824332,0.00022878089,0.000069439375,0.14269008],"genre_scores_gemma":[0.030741245,0.009114507,0.04201947,0.0009158216,0.0019033862,0.00069120614,0.0017427761,0.0006271632,0.91224444],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989104,0.00007246404,0.00037527687,0.0003582497,0.000102876395,0.00018068096],"domain_scores_gemma":[0.9991632,0.000053656433,0.00024686387,0.00039215284,0.00010784831,0.000036283243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035197544,0.0002569949,0.00031203052,0.00009088214,0.000074525175,0.000023262877,0.00024295355,0.00035741634,0.0000820756],"category_scores_gemma":[0.00003159296,0.00020892345,0.0001784256,0.000008798287,0.00010632296,0.0000017330764,0.000058696784,0.00013364422,3.6324803e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026182667,0.00004984681,0.00000659404,0.0006054277,0.0006342669,0.0000026743862,0.000376775,0.0014052403,0.56133085,0.10939788,0.009944396,0.31598422],"study_design_scores_gemma":[0.00028468104,0.0002238564,6.0328756e-7,0.000052455554,0.0000776269,0.0000013975346,0.0000061003043,0.0009118901,0.208599,0.0014073264,0.788203,0.00023204219],"about_ca_topic_score_codex":0.000027464414,"about_ca_topic_score_gemma":0.00003144548,"teacher_disagreement_score":0.7782586,"about_ca_system_score_codex":0.000009437738,"about_ca_system_score_gemma":0.000018131683,"threshold_uncertainty_score":0.85196507},"labels":[],"label_agreement":null},{"id":"W2479668931","doi":"10.1038/ncomms12344","title":"Evolution of a G protein-coupled receptor response by mutations in regulatory network interactions","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto; Danmarks Grundforskningsfond; National Research Foundation","keywords":"Saccharomyces cerevisiae; Mutant; Receptor; Yeast; Biology; Signal transduction; Ligand (biochemistry); Pheromone; Mutation; Genetics; Cell biology; Gene","score_opus":0.007888621772255355,"score_gpt":0.2664318922164583,"score_spread":0.25854327044420294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2479668931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841017,0.0062327813,0.006167203,0.0025269017,0.00017464183,0.00043290833,0.000082245,0.000021544358,0.0002600668],"genre_scores_gemma":[0.99225605,0.00014290848,0.0064746216,0.000048201666,0.000047442452,0.00012588695,0.00014437758,0.00001626309,0.00074423425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901915,0.0002931356,0.00027148635,0.00017689657,0.00009394896,0.00014538798],"domain_scores_gemma":[0.99857795,0.00011583381,0.00014430683,0.00095135975,0.00016944321,0.00004110261],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004534846,0.00009426684,0.0001083508,0.000072183364,0.00012022317,0.0000072296098,0.0004146507,0.00022735374,0.000069988855],"category_scores_gemma":[0.00036416895,0.00007898223,0.00006170397,0.00022271105,0.00010170815,0.000010822029,0.00013752552,0.00022831779,0.0000076115844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016102273,0.00007697474,0.00049477763,0.0000020135815,0.000017366196,4.761711e-8,0.000029271694,0.000031084175,0.9916121,0.0030365062,0.004067447,0.00047138854],"study_design_scores_gemma":[0.0015175226,0.00031127277,0.0064771282,0.00032490378,0.00002868667,0.0000066622365,0.00031194152,0.0005270399,0.62408113,0.0018274529,0.36413684,0.00044943474],"about_ca_topic_score_codex":0.000020324716,"about_ca_topic_score_gemma":0.00026129777,"teacher_disagreement_score":0.36753097,"about_ca_system_score_codex":0.000081014,"about_ca_system_score_gemma":0.000119444056,"threshold_uncertainty_score":0.3220802},"labels":[],"label_agreement":null},{"id":"W2485805415","doi":"10.1385/0-89603-509-3:1","title":"Characterization of Receptors by Radiolabeled Ligand-Binding Techniques","year":2003,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Medical Research Council","keywords":"Radioligand; Receptor; Ligand (biochemistry); Radioligand Assay; Chemistry; Biophysics; Ligand binding assay; Computational biology; Biology; Biochemistry","score_opus":0.020089150836252838,"score_gpt":0.22910297600282892,"score_spread":0.20901382516657607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2485805415","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0375116,0.008881463,0.005314469,0.000011975146,0.0013010944,0.0021106312,0.00046988338,0.00016733276,0.94423157],"genre_scores_gemma":[0.009658145,0.004917538,0.0007385109,0.0001677425,0.00053435063,0.000075087235,0.0022003045,0.00025209898,0.9814562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986812,0.00003184577,0.00043136746,0.00045584608,0.00018918408,0.00021054775],"domain_scores_gemma":[0.998992,0.0000052477235,0.00044035638,0.00038931333,0.00010577784,0.00006730254],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016313877,0.000349448,0.00039198398,0.00007614135,0.00008334957,0.00003178379,0.00023609304,0.00061427406,0.00011550172],"category_scores_gemma":[0.000008525952,0.00036323204,0.00017236258,0.0000043170526,0.00007208488,0.0000031520767,0.0000784532,0.00018443589,0.0000022064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024187038,0.000008222568,2.6186368e-7,0.000063653555,0.00011246748,0.0000010208607,0.000036220208,9.782274e-8,0.97982556,0.0068497304,0.002827591,0.010250964],"study_design_scores_gemma":[0.00009392189,0.00010197291,3.5965147e-8,0.00009212407,0.00003337911,0.0000019110614,0.0000012086963,5.8278783e-7,0.557041,0.00012630818,0.44229952,0.00020804851],"about_ca_topic_score_codex":0.000008284312,"about_ca_topic_score_gemma":0.0000017418802,"teacher_disagreement_score":0.43947193,"about_ca_system_score_codex":0.000020437434,"about_ca_system_score_gemma":0.000027892362,"threshold_uncertainty_score":0.999882},"labels":[],"label_agreement":null},{"id":"W2486084896","doi":"10.1007/978-1-62703-779-2_7","title":"Signalosome Profiling Reveals Allosteric Interactions Between G Protein-Coupled Receptors","year":2013,"lang":"en","type":"book-chapter","venue":"Methods in pharmacology and toxicology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Allosteric regulation; Profiling (computer programming); Computational biology; Receptor; Biology; Chemistry; Computer science; Genetics","score_opus":0.039640706934675765,"score_gpt":0.36937667078017694,"score_spread":0.3297359638455012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2486084896","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5995457,0.018587919,0.121592,0.0024458074,0.017128708,0.015616688,0.00025309963,0.00032959692,0.22450048],"genre_scores_gemma":[0.09247838,0.0024004139,0.34985802,0.0026978361,0.0048509967,0.0018843437,0.0007566573,0.00046605009,0.54460734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968009,0.00070877693,0.00082592,0.0009926794,0.000106535575,0.000565177],"domain_scores_gemma":[0.99866486,0.00027701096,0.0004614227,0.00028190788,0.00012090103,0.00019390084],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012183395,0.0005698768,0.0009243191,0.0003337702,0.00015049647,0.000026256583,0.00032945385,0.0013310682,0.005324078],"category_scores_gemma":[0.00010507979,0.0005753092,0.00018838275,0.000061536586,0.00022926232,0.000012855295,0.00037871153,0.0010339828,0.000057755307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011096209,0.00004084093,0.00009216436,0.00008220353,0.00033900666,0.000016697804,0.00003508148,0.0000075289636,0.9844544,0.003003164,0.0009328616,0.010885105],"study_design_scores_gemma":[0.0016186318,0.0013808818,0.00004946844,0.000132027,0.0003491051,0.00007978595,0.00003453764,0.00015584516,0.77594537,0.03488003,0.18421105,0.0011632532],"about_ca_topic_score_codex":0.0000062688337,"about_ca_topic_score_gemma":0.0000058328546,"teacher_disagreement_score":0.5070673,"about_ca_system_score_codex":0.000072370014,"about_ca_system_score_gemma":0.00012020104,"threshold_uncertainty_score":0.9999654},"labels":[],"label_agreement":null},{"id":"W2488199799","doi":"10.1016/j.bpj.2015.11.2385","title":"CaV2.3 Mediate ATP Release from Rat Tail Artery Sympathetic Nerves","year":2016,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Vesicle; Biology; Neurotransmission; Synaptic vesicle; Norepinephrine; Sympathetic nervous system; Neuroeffector; Receptor; Cell biology; Internal medicine; Endocrinology; Chemistry; Medicine; Biochemistry; Dopamine","score_opus":0.008414840405347793,"score_gpt":0.21491265371439444,"score_spread":0.20649781330904665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2488199799","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99231017,0.00023636062,0.0060136146,0.0006410844,0.00065537484,0.00004903519,0.000024964713,0.000012566984,0.000056855948],"genre_scores_gemma":[0.99602824,0.0002904963,0.00037658864,0.00025516297,0.0025636647,0.00000432435,0.000015265441,0.00002850474,0.00043777243],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998874,0.00008899644,0.0002459793,0.00027691133,0.00021395688,0.00030015627],"domain_scores_gemma":[0.9992783,0.000025753388,0.0001219184,0.00023261059,0.0000733131,0.0002680865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010829873,0.00017720653,0.00018166515,0.000027359261,0.00011601059,0.000062227344,0.00022297504,0.00012926124,0.00026361115],"category_scores_gemma":[0.00005182671,0.00010883242,0.00022831695,0.00004247604,0.000071478105,0.000010164774,0.00006991865,0.00012686747,0.00013116686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005508895,0.00005983852,0.00006935223,0.0000011809104,0.00004546687,0.000034422126,0.0000398746,0.00000365534,0.9861535,0.00006438711,0.0009941764,0.012479092],"study_design_scores_gemma":[0.0006985108,0.00028984292,0.00022037611,0.000047487225,0.00002725023,0.000034557524,0.00003120013,0.000036817928,0.98459035,0.0005367137,0.013271016,0.00021585764],"about_ca_topic_score_codex":0.000005984201,"about_ca_topic_score_gemma":0.0000013915296,"teacher_disagreement_score":0.012276839,"about_ca_system_score_codex":0.0000189584,"about_ca_system_score_gemma":0.000056801193,"threshold_uncertainty_score":0.44380572},"labels":[],"label_agreement":null},{"id":"W2488539909","doi":"10.1385/0-89603-078-4:139","title":"Muscarinic Cholinergic Receptors","year":2003,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Muscarinic acetylcholine receptor; Cholinergic; Nicotinic agonist; Neuroscience; Acetylcholine; Acetylcholine receptor; Neurotransmitter receptor; Muscarinic acetylcholine receptor M4; Muscarinic acetylcholine receptor M5; Biology; Receptor; Neurotransmitter; Population; Muscarinic acetylcholine receptor M2; Cholinergic neuron; Central nervous system; Endocrinology; Muscarinic acetylcholine receptor M3; Internal medicine; Medicine; Biochemistry","score_opus":0.03941583062131713,"score_gpt":0.24727421038892,"score_spread":0.20785837976760288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2488539909","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00035988024,0.009730417,0.00021460923,0.00000474492,0.0010844994,0.00034551695,0.00002465558,0.000041919222,0.98819375],"genre_scores_gemma":[0.0028026206,0.0020689506,0.00030463867,0.00039771965,0.0010211053,0.00003734224,0.00024848556,0.00018687414,0.99293226],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982293,0.000034288852,0.00040520998,0.00073724857,0.0002460521,0.00034787797],"domain_scores_gemma":[0.99874425,0.000007023738,0.00024447433,0.0007613684,0.00009780412,0.0001450883],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016272567,0.00049761974,0.00038771058,0.00007120564,0.00012865696,0.00005761808,0.00037430035,0.00075332687,0.0007624841],"category_scores_gemma":[0.000010983786,0.0005029316,0.0003510318,0.0000030603246,0.00009606791,0.0000016496462,0.00017434222,0.00034776423,0.00003429576],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002121894,0.0000753602,0.0000012453087,0.00037307123,0.0015567129,0.000078917874,0.00029086828,0.00018000252,0.080348395,0.61525863,0.1808868,0.12073779],"study_design_scores_gemma":[0.00030857287,0.00015058432,2.3089683e-7,0.000063935615,0.00008006249,0.000010193994,0.0000034194813,0.000003736433,0.038277,0.0021656773,0.9583778,0.00055879226],"about_ca_topic_score_codex":0.000018381656,"about_ca_topic_score_gemma":0.000017538718,"teacher_disagreement_score":0.777491,"about_ca_system_score_codex":0.000022876831,"about_ca_system_score_gemma":0.000048190836,"threshold_uncertainty_score":0.9997422},"labels":[],"label_agreement":null},{"id":"W2489452039","doi":"10.1007/s12035-016-9954-7","title":"The Interaction of TXNIP and AFq1 Genes Increases the Susceptibility of Schizophrenia","year":2016,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"TXNIP; Schizophrenia (object-oriented programming); DISC1; Gene; Biology; Genetics; Computational biology; Medicine; Neuroscience; Psychiatry","score_opus":0.00739332086040396,"score_gpt":0.22904738144354503,"score_spread":0.22165406058314108,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2489452039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968122,0.0010746825,0.001515345,0.00027830206,0.00013750802,0.00012443785,0.0000125823,0.0000037901536,0.00004112289],"genre_scores_gemma":[0.9991569,0.0005529659,0.00009485355,0.00009104321,0.00004090156,0.000008116294,0.000006360823,0.0000102924205,0.000038597867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990858,0.00027854,0.00022242843,0.000226515,0.000049281844,0.0001374765],"domain_scores_gemma":[0.9992887,0.00011007595,0.0001398706,0.00035652655,0.00007857282,0.00002630382],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002543665,0.000102780185,0.00012861114,0.000017822542,0.00007012408,0.0000059126164,0.00018649292,0.00008380859,0.00001651297],"category_scores_gemma":[0.00019616955,0.00004838525,0.000082480125,0.00004017621,0.0003097876,0.0000029142834,0.00014687412,0.00004773453,9.726751e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017388833,0.000017701579,0.0009636561,0.0000058091573,0.00003211041,5.400189e-7,0.000005455508,0.0000060312805,0.9897216,0.00080939813,0.000054226548,0.0082095675],"study_design_scores_gemma":[0.0002729383,0.00034963465,0.0017481117,0.000008898598,0.000014966316,0.000018646622,0.00003116308,0.000006291922,0.99386644,0.00041334517,0.003208434,0.000061107625],"about_ca_topic_score_codex":0.000035566314,"about_ca_topic_score_gemma":0.000035596106,"teacher_disagreement_score":0.008148461,"about_ca_system_score_codex":0.0000029236091,"about_ca_system_score_gemma":0.000026686394,"threshold_uncertainty_score":0.19730932},"labels":[],"label_agreement":null},{"id":"W2489654145","doi":"10.1016/j.bpj.2016.11.184","title":"Single-Molecule Analysis of the Supramolecular Organization of the M2 Muscarinic Receptor and the Gα i1 Protein","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Mastoparan; Random hexamer; G protein; Förster resonance energy transfer; Tetramer; G protein-coupled receptor; Green fluorescent protein; Photobleaching; Biophysics; Heterotrimeric G protein; Chemistry; Biology; Receptor; Biochemistry; Fluorescence","score_opus":0.007610007536762953,"score_gpt":0.22038213553096803,"score_spread":0.21277212799420508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2489654145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99743295,0.000050254206,0.0015529563,0.0005933838,0.00012861911,0.00015802812,0.000007586025,0.0000013170181,0.00007488794],"genre_scores_gemma":[0.99952734,0.000026573392,0.000128538,0.000061944214,0.00014886829,0.0000022962015,0.0000035937305,0.000012145449,0.000088702946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990741,0.00018650749,0.00023938075,0.00014738005,0.00023304907,0.000119601216],"domain_scores_gemma":[0.99872845,0.000012220708,0.0004858887,0.0005370238,0.00019720107,0.000039204184],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002644369,0.000103579165,0.00020131255,0.000021172615,0.00040017543,0.00008173892,0.0005762494,0.00008185884,0.000031614225],"category_scores_gemma":[0.0003404234,0.00004871048,0.0002946767,0.00018958154,0.00035458198,0.000006039068,0.00027222995,0.00013977136,4.664e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000323757,0.000045641107,0.00073089084,0.0000048046154,0.0002922567,1.9460494e-7,0.000056959612,0.00002807047,0.9976145,0.00072060054,0.000026091515,0.0004476204],"study_design_scores_gemma":[0.0004464621,0.00007042908,0.0050026802,0.0000226599,0.0002852164,0.000004050602,0.000044395754,0.00018579324,0.9935216,0.00009282028,0.00025733214,0.00006659101],"about_ca_topic_score_codex":0.000021067619,"about_ca_topic_score_gemma":0.000004363325,"teacher_disagreement_score":0.0042717895,"about_ca_system_score_codex":0.000007885388,"about_ca_system_score_gemma":0.000049582162,"threshold_uncertainty_score":0.3077866},"labels":[],"label_agreement":null},{"id":"W2491156807","doi":"10.1016/j.bpj.2015.11.2285","title":"Lipid Protein Interactions Of G Protein Coupled Receptors","year":2016,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"G protein-coupled receptor; Lipid bilayer; Computational biology; Receptor; Protein–protein interaction; Molecular dynamics; Lipid raft; Chemistry; Biology; Bioinformatics; Biochemistry; Membrane","score_opus":0.010407868507475701,"score_gpt":0.24439450258839784,"score_spread":0.23398663408092213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2491156807","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9776987,0.00001874046,0.021389343,0.00030976307,0.00028416776,0.00015714412,0.0000054137554,0.0000066384496,0.00013010048],"genre_scores_gemma":[0.9960401,0.000019257139,0.0013117642,0.000020561089,0.0010634147,0.000016635935,0.00000314218,0.000017393166,0.0015077338],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917376,0.00006115932,0.00025462612,0.00016551952,0.00016178597,0.0001831651],"domain_scores_gemma":[0.9994126,0.000007950614,0.00017595511,0.00015090698,0.00013768837,0.00011490116],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013376918,0.00011454079,0.00014400823,0.00003672688,0.00007387704,0.000019372446,0.00015838507,0.00007162391,0.00040375773],"category_scores_gemma":[0.00008232626,0.00007187011,0.00016767925,0.00006148997,0.000061270955,0.000008655876,0.000048833528,0.00010703732,0.000025822008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010812268,0.0000947257,0.00001819378,0.0000053734093,0.000039262886,0.0000011764747,0.00000991498,0.0000012846631,0.99219006,0.0003510224,0.00021901108,0.006961868],"study_design_scores_gemma":[0.000408919,0.00044054235,0.00003057621,0.00010184526,0.000007266704,0.00001643712,0.00001763931,0.000017316861,0.9859115,0.00022432461,0.012709686,0.00011396343],"about_ca_topic_score_codex":0.0000034887605,"about_ca_topic_score_gemma":8.695996e-7,"teacher_disagreement_score":0.020077579,"about_ca_system_score_codex":0.00001758884,"about_ca_system_score_gemma":0.00005901635,"threshold_uncertainty_score":0.4420864},"labels":[],"label_agreement":null},{"id":"W2492142443","doi":"10.1523/eneuro.0202-16.2016","title":"GPR88 in A<sub>2A</sub>R Neurons Enhances Anxiety-Like Behaviors","year":2016,"lang":"en","type":"article","venue":"eNeuro","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute on Drug Abuse; National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Walloon excellence in life sciences and biotechnology","keywords":"Elevated plus maze; Novelty seeking; Anxiety; Chemistry; Conditioned place preference; Receptor; Psychology; Pharmacology; Endocrinology; Biology; Biochemistry; Psychiatry","score_opus":0.006370333075993546,"score_gpt":0.2218850191589072,"score_spread":0.21551468608291366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2492142443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975791,0.00021904959,0.0010571096,0.00016464524,0.00053389056,0.00010657141,0.000013473116,0.00001928175,0.0003068884],"genre_scores_gemma":[0.9979087,0.0009253153,0.000100094236,0.00035541895,0.00018026627,0.000026686488,0.0000138290325,0.000031471944,0.00045819342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988994,0.00007186472,0.00019064709,0.00041876442,0.00012303206,0.00029631113],"domain_scores_gemma":[0.9995329,0.000015919371,0.000054757595,0.0002874279,0.000026344014,0.000082652055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117386066,0.00015844552,0.00012455606,0.00004756106,0.000049188606,0.000017829718,0.00019163874,0.00011334628,0.00008119702],"category_scores_gemma":[0.000048206897,0.00012258708,0.00008611497,0.00007992082,0.00004047119,0.000006195716,0.00006442067,0.000077983066,0.000049778697],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020314314,0.000037657403,0.0011639389,0.0000028166114,0.0000038606613,0.0000090383055,0.000014758149,0.000009073001,0.9882898,0.000022230775,0.0009878716,0.009438657],"study_design_scores_gemma":[0.00030344594,0.00016728837,0.001213243,0.000014861703,0.0000057758225,0.000010570945,0.000009124158,0.0000036114293,0.9734247,0.00005059577,0.024626233,0.00017056655],"about_ca_topic_score_codex":0.000007723601,"about_ca_topic_score_gemma":0.00004041796,"teacher_disagreement_score":0.023638362,"about_ca_system_score_codex":0.0000089900195,"about_ca_system_score_gemma":0.000035403147,"threshold_uncertainty_score":0.4998956},"labels":[],"label_agreement":null},{"id":"W2492963788","doi":"10.1142/9789814366700_0006","title":"The Role of CREB and CREB Co-activators in Memory Formation","year":2012,"lang":"en","type":"book-chapter","venue":"WORLD SCIENTIFIC eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"CREB; Neuroscience; Psychology; Computer science; Biology; Transcription factor; Genetics; Gene","score_opus":0.011017811624544759,"score_gpt":0.22056271918690143,"score_spread":0.20954490756235666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2492963788","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.054218363,0.006034597,0.0000790327,0.000013320976,0.00071812666,0.00045877972,0.00003880599,0.000010241655,0.93842876],"genre_scores_gemma":[0.43766284,0.000026641437,0.00007861536,0.000015819447,0.000120686214,0.00000953863,0.000066880966,0.000025351163,0.56199366],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990095,0.000025430681,0.0002902723,0.00026675404,0.0002023273,0.00020572984],"domain_scores_gemma":[0.9993087,0.00001921979,0.00020758498,0.00034303937,0.00005750161,0.00006397768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062408415,0.0001656243,0.0001679849,0.0001302284,0.00019806738,0.00007124634,0.0001714275,0.00014759612,0.000075541044],"category_scores_gemma":[0.0000072901053,0.00012982638,0.00008056426,0.000016949893,0.00024445073,0.0000049809555,0.00008872067,0.00014236603,0.0000069159655],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040425377,0.000007603816,0.000020910453,0.000030124753,0.000028371798,5.170156e-7,0.00033550846,0.0000018687455,0.9404149,0.021090083,0.0012203907,0.03680932],"study_design_scores_gemma":[0.000086099215,0.000017488901,0.000004377973,0.00004302511,0.000008743477,0.0000018461486,0.00007382472,0.000012069003,0.46378812,0.002366049,0.5334869,0.00011147045],"about_ca_topic_score_codex":0.0000040310356,"about_ca_topic_score_gemma":0.00033903788,"teacher_disagreement_score":0.5322665,"about_ca_system_score_codex":0.00001670957,"about_ca_system_score_gemma":0.00005121996,"threshold_uncertainty_score":0.5294166},"labels":[],"label_agreement":null},{"id":"W2495191067","doi":"10.1385/0-89603-490-9:139","title":"G Proteins and Animal Models of Parkinson's Disease","year":2003,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Parkinsonfonden","keywords":"Receptor; 5-HT5A receptor; Enzyme-linked receptor; Protease-activated receptor 2; Interleukin-21 receptor; Dopamine receptor; Neurotransmitter receptor; G protein-coupled receptor; Desensitization (medicine); Signal transduction; Receptor antagonist; Pharmacology; Cell biology; Chemistry; Biology; Internal medicine; Medicine; Antagonist","score_opus":0.03908462104379877,"score_gpt":0.2325881112860765,"score_spread":0.19350349024227775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2495191067","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0072590406,0.04536894,0.0027355596,0.000010152898,0.00017053622,0.00139822,0.00024825684,0.000030919542,0.94277835],"genre_scores_gemma":[0.3536586,0.0040724846,0.0017013082,0.00024975892,0.0005516922,0.00013322767,0.00019903143,0.00025299736,0.6391809],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989583,0.000020174939,0.00023847134,0.00044638774,0.000163183,0.00017347945],"domain_scores_gemma":[0.9992384,0.0000034150848,0.00017815107,0.00037748282,0.000069138325,0.00013345032],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00008281804,0.00027819994,0.00026846427,0.00003823218,0.00006112518,0.000023188475,0.00014580025,0.0002644185,0.000048446956],"category_scores_gemma":[0.00000515911,0.0002752577,0.00013328157,0.0000013537448,0.00010816463,0.0000020731254,0.00012424952,0.0001234008,5.534734e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055882544,0.00004773705,0.0000017199801,0.00072563946,0.00047339572,0.000044573215,0.00015721637,0.00009280097,0.1435697,0.83595055,0.0026091791,0.015768642],"study_design_scores_gemma":[0.00043678636,0.0003383741,0.0000025263666,0.00018510075,0.00014664837,0.0000044815256,0.00000407841,0.000115272735,0.097070225,0.01945008,0.8816986,0.0005478179],"about_ca_topic_score_codex":0.000012720877,"about_ca_topic_score_gemma":0.000005346157,"teacher_disagreement_score":0.8790894,"about_ca_system_score_codex":0.000005771922,"about_ca_system_score_gemma":0.000040779276,"threshold_uncertainty_score":0.99996996},"labels":[],"label_agreement":null},{"id":"W2496036998","doi":"10.1016/b978-012370509-9.00004-8","title":"The Molecular Mechanisms of Reward","year":2008,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Psychology","score_opus":0.008603724452480244,"score_gpt":0.21331919000852842,"score_spread":0.20471546555604817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2496036998","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003095161,0.007136487,0.00095795945,0.00003054905,0.0004154727,0.00039355727,0.000027277933,0.000014235846,0.99071497],"genre_scores_gemma":[0.00741487,0.002046703,0.0011466201,0.00021645283,0.000230708,0.000025564992,0.000058692724,0.0001212998,0.9887391],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99853826,0.00003325444,0.00043023343,0.0004161201,0.0003176358,0.00026447125],"domain_scores_gemma":[0.9986914,0.000015612193,0.0003108652,0.0007461195,0.00015009417,0.000085925596],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023652951,0.0003474517,0.0003500908,0.000041161038,0.00015648785,0.000018117515,0.00043525046,0.00046714244,0.000070713366],"category_scores_gemma":[0.000022191143,0.00026437256,0.0004171377,0.0000072835464,0.00015424762,8.08855e-7,0.00019057009,0.0002282229,0.000022038877],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004473398,0.000007633891,1.3848415e-7,0.00003470816,0.0002805013,0.000025247447,0.000036937738,0.0000046152363,0.42729166,0.03736234,0.0005657022,0.5343458],"study_design_scores_gemma":[0.00012097343,0.00015929861,1.4737743e-7,0.000062046536,0.000039915474,0.000023064247,0.0000049431897,0.0000011902379,0.29350677,0.012112129,0.6937442,0.00022534728],"about_ca_topic_score_codex":3.2673157e-7,"about_ca_topic_score_gemma":0.0000036857157,"teacher_disagreement_score":0.6931785,"about_ca_system_score_codex":0.000014324575,"about_ca_system_score_gemma":0.00013064977,"threshold_uncertainty_score":0.99998087},"labels":[],"label_agreement":null},{"id":"W2500252451","doi":"10.1385/0-89603-490-9:353","title":"G Proteins and Mood Disorders","year":2003,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Monoaminergic; Serotonergic; Neuroscience; Mood disorders; Mood; Neurotransmitter systems; Neurotransmitter receptor; Psychology; Dopaminergic; Cholinergic; Neurotransmitter; Serotonin; Receptor; Biology; Medicine; Internal medicine; Dopamine; Psychiatry; Central nervous system","score_opus":0.021450268098557695,"score_gpt":0.22521229421767053,"score_spread":0.20376202611911284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2500252451","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003226997,0.0078194775,0.0007761494,0.000008198468,0.00015342009,0.00055993046,0.000025494788,0.000020290332,0.99031436],"genre_scores_gemma":[0.01479486,0.0026434825,0.00063494325,0.00017128699,0.00035781987,0.000078694255,0.00010052756,0.0001482578,0.9810701],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989834,0.000016910164,0.00019179044,0.00047452553,0.00013046367,0.0002029015],"domain_scores_gemma":[0.99940425,0.000003229833,0.00011508472,0.0003610141,0.000033404605,0.00008298845],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00007567227,0.00030368348,0.00021985464,0.000033930995,0.000106943895,0.00004456607,0.00014321308,0.00039399945,0.000103734754],"category_scores_gemma":[0.0000055037544,0.00030072557,0.00011255786,0.0000011689315,0.00008939611,0.0000011503553,0.00011552341,0.00017227688,0.0000031107104],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012828535,0.000047602804,0.000002113929,0.0004532391,0.0008459799,0.00001165304,0.00029186852,0.00001564592,0.115637794,0.75639683,0.0082915425,0.117877446],"study_design_scores_gemma":[0.0003131509,0.00019997956,7.5491977e-7,0.00005798158,0.000053296575,0.0000055687456,0.000004388846,0.0000034775348,0.0374902,0.00991432,0.95153624,0.00042067168],"about_ca_topic_score_codex":0.000019218163,"about_ca_topic_score_gemma":0.00008558318,"teacher_disagreement_score":0.9432447,"about_ca_system_score_codex":0.000006445829,"about_ca_system_score_gemma":0.0000201801,"threshold_uncertainty_score":0.9999445},"labels":[],"label_agreement":null},{"id":"W2500597217","doi":"10.1007/978-1-4939-3539-0_8","title":"A Functional Assay for GPR55: Envision Protocol","year":2016,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute on Drug Abuse; National Institutes of Health; University of Aberdeen; GW Pharmaceuticals","keywords":"Phosphorylation; Chemistry; Enzyme; Antibody; Cell biology; Computational biology; Molecular biology; Biochemistry; Biology; Immunology","score_opus":0.028493244012810292,"score_gpt":0.39681874171323867,"score_spread":0.3683254977004284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2500597217","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001884855,0.000054610173,0.9881355,0.00026127754,0.00022846635,0.009161744,0.000013019388,0.000012277413,0.00024823198],"genre_scores_gemma":[0.003672207,0.000008108715,0.95708,0.0005286546,0.0002259115,0.037705123,0.00004856673,0.000041287527,0.000690122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980973,0.00068879663,0.00029396237,0.0005279681,0.00006113538,0.00033081765],"domain_scores_gemma":[0.9993498,0.0001244545,0.00009149397,0.00030026413,0.00007387432,0.000060143862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001729282,0.00017657338,0.00020348247,0.000086951775,0.000048672995,0.0000086871305,0.00017618062,0.00032816516,0.00019733193],"category_scores_gemma":[0.0007005203,0.00012103422,0.0001547082,0.00007611469,0.00007098606,0.0000023955447,0.00010701641,0.000065617074,0.0000067092114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017781182,0.000035283138,0.00018622189,0.000009068317,0.000021596463,0.0000012145653,0.0000035112128,0.000009915386,0.9183803,0.0042453175,0.00021118013,0.07671856],"study_design_scores_gemma":[0.0012348803,0.0004479438,0.000046684367,0.000014512465,0.0000048223337,0.000006983555,0.0000050707436,0.00004835619,0.85689753,0.013885787,0.12723294,0.00017449449],"about_ca_topic_score_codex":0.0000033704302,"about_ca_topic_score_gemma":0.0000025977504,"teacher_disagreement_score":0.12702176,"about_ca_system_score_codex":0.000022100005,"about_ca_system_score_gemma":0.000057616657,"threshold_uncertainty_score":0.49356323},"labels":[],"label_agreement":null},{"id":"W2501635289","doi":"10.1007/978-1-4939-2196-6_1","title":"Genetic and Epigenetic Methods for Analysis of the Dopamine D2 Receptor Gene","year":2014,"lang":"en","type":"book-chapter","venue":"Neuromethods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Epigenetics; Dopamine receptor D2; Genetics; Dopamine; Biology; Gene; Computational biology; Neuroscience","score_opus":0.029280499853494405,"score_gpt":0.3214331437076998,"score_spread":0.2921526438542054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2501635289","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012605081,0.0061920807,0.9747621,0.00007109186,0.0010665283,0.0008343992,0.00019245957,0.000014511584,0.0042617596],"genre_scores_gemma":[0.003064382,0.0026352287,0.88648045,0.00039085263,0.00058627664,0.00006843531,0.00016001794,0.00019456654,0.10641978],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99788165,0.0003700288,0.0005619167,0.00075903477,0.0001692472,0.0002581449],"domain_scores_gemma":[0.99810296,0.00023414278,0.0004782815,0.00090494676,0.00017229443,0.00010734229],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009960487,0.00040055386,0.0007944411,0.0002283911,0.00010114357,0.000023998999,0.00041870412,0.00049143884,0.00020214585],"category_scores_gemma":[0.00028842597,0.0003149894,0.0006969306,0.00013312421,0.00015216558,0.000001039643,0.00026156442,0.00018032626,9.01469e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035794143,0.000007955754,0.000032762717,0.00006459385,0.00080151914,2.2292383e-7,0.000011386963,0.00012561177,0.8928486,0.0008703716,0.00015698647,0.105044186],"study_design_scores_gemma":[0.00032839822,0.00054894644,0.00046529496,0.000029035038,0.0024669417,0.000008112483,0.0000024452859,0.0008986273,0.5988618,0.0017672792,0.39415944,0.00046369346],"about_ca_topic_score_codex":0.0000041132357,"about_ca_topic_score_gemma":0.000003982047,"teacher_disagreement_score":0.39400244,"about_ca_system_score_codex":0.000010327275,"about_ca_system_score_gemma":0.00005247921,"threshold_uncertainty_score":0.9999302},"labels":[],"label_agreement":null},{"id":"W2502010969","doi":"10.1385/0-89603-510-7:1","title":"Quantitative Autoradiography of Monoamine Uptake Sites and Receptors in Rat and Mouse Brain","year":2003,"lang":"en","type":"book-chapter","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec","funders":"","keywords":"Receptor; Monoamine neurotransmitter; Central nervous system; Distribution (mathematics); Biology; Neuroscience; Cell biology; Pharmacology; Chemistry; Biochemistry; Serotonin","score_opus":0.03684590567380471,"score_gpt":0.2550538386244826,"score_spread":0.2182079329506779,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2502010969","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45760313,0.20393188,0.0010295968,0.0000522981,0.000754379,0.0026821531,0.00033878477,0.00007497257,0.3335328],"genre_scores_gemma":[0.10397001,0.025055252,0.010018428,0.0006829056,0.00040243752,0.00013026482,0.0007319358,0.0005208359,0.8584879],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988563,0.00004408605,0.00034382453,0.00046712835,0.00011335416,0.00017529036],"domain_scores_gemma":[0.99939376,0.000026698797,0.00020305865,0.0002475028,0.00005645947,0.000072498005],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018629091,0.00030704605,0.00039292488,0.00016096867,0.00004689208,0.000028240484,0.00010448067,0.00034920636,0.00003138358],"category_scores_gemma":[0.000020782045,0.00030880273,0.00009926228,0.0000066200373,0.00018801863,0.0000031404304,0.000083035506,0.00016045415,2.4869618e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036282343,0.00005051419,0.00004306547,0.0004949662,0.0006177448,0.000020216494,0.0012724748,0.000021463937,0.7207398,0.24782738,0.0069353646,0.02161419],"study_design_scores_gemma":[0.0012771391,0.0011600923,0.000010607121,0.00024816545,0.0000935797,0.000008829504,0.00009625211,0.00005519808,0.33950886,0.0041769156,0.65247774,0.0008866385],"about_ca_topic_score_codex":0.000035507484,"about_ca_topic_score_gemma":0.00007936779,"teacher_disagreement_score":0.6455424,"about_ca_system_score_codex":0.0000062658983,"about_ca_system_score_gemma":0.000015483316,"threshold_uncertainty_score":0.9999364},"labels":[],"label_agreement":null},{"id":"W2502173943","doi":"10.1007/978-1-4939-3798-1_2","title":"Structure and Function of G-Protein-Coupled Receptor Kinases 1 and 7","year":2016,"lang":"en","type":"book-chapter","venue":"Methods in pharmacology and toxicology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health Canada; National Institutes of Health; Foundation Fighting Blindness; Arnold and Mabel Beckman Foundation","keywords":"G protein-coupled receptor kinase; G protein-coupled receptor; Rhodopsin; Beta adrenergic receptor kinase; Kinase; Rhodopsin-like receptors; Biology; Cell biology; Arrestin; Receptor; Signal transduction; Biochemistry; Agonist; Retinal","score_opus":0.017942556632037837,"score_gpt":0.3254241434038041,"score_spread":0.3074815867717663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2502173943","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93602395,0.035408095,0.013989443,0.0004321598,0.002538646,0.0013809418,0.00019108034,0.000025592302,0.01001007],"genre_scores_gemma":[0.6745248,0.034545235,0.15105972,0.002839902,0.0029859017,0.00025985466,0.00024515617,0.0003607359,0.13317871],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854535,0.00026564774,0.00034725788,0.0005645248,0.00005118855,0.00022601137],"domain_scores_gemma":[0.99935114,0.00014163641,0.00023755193,0.00012859398,0.000056073317,0.00008502312],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00051271636,0.00029709103,0.00052540697,0.00015027836,0.000063522355,0.0000058136816,0.00008484346,0.0010351657,0.0012132429],"category_scores_gemma":[0.00005506877,0.00025217887,0.000049793303,0.000018464816,0.00041537147,0.0000046965215,0.00019676652,0.00028689185,6.631648e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043520547,0.000012337559,0.000050176794,0.00008022346,0.00014358724,0.0000042861525,0.00001889494,6.8100366e-7,0.9396678,0.008553209,0.000107954875,0.050925627],"study_design_scores_gemma":[0.0017084649,0.0013678683,0.00011923839,0.000060190676,0.00016481383,0.000043635824,0.000011295195,0.000023426426,0.8950553,0.030408327,0.070661135,0.00037630709],"about_ca_topic_score_codex":0.0000020529146,"about_ca_topic_score_gemma":0.000009076183,"teacher_disagreement_score":0.2614992,"about_ca_system_score_codex":0.00001215072,"about_ca_system_score_gemma":0.00005150086,"threshold_uncertainty_score":0.999993},"labels":[],"label_agreement":null},{"id":"W2505532605","doi":"10.1016/j.cell.2016.07.004","title":"GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling","year":2016,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":569,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Heart, Lung, and Blood Institute; Lundbeckfonden; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Biology; G protein-coupled receptor; Arrestin; G protein; Cell biology; Signal transduction","score_opus":0.011696002017740062,"score_gpt":0.21768572565039088,"score_spread":0.2059897236326508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2505532605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887408,0.00028757862,0.008793449,0.00026056534,0.000091980364,0.00056670944,0.000013338319,0.00004037803,0.0012052221],"genre_scores_gemma":[0.9902245,0.000012309597,0.0033578582,0.00007960008,0.00046003843,0.00010250959,0.00004625573,0.000045101657,0.0056718634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986577,0.00007745538,0.0002475024,0.0004281306,0.00017269752,0.0004165387],"domain_scores_gemma":[0.99932706,0.000015697835,0.000085175,0.00031695553,0.00011529897,0.00013980908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026397753,0.00021170646,0.00016666073,0.000041645857,0.0001069395,0.000034270495,0.00025473072,0.00016464907,0.0008022624],"category_scores_gemma":[0.0001204507,0.0001494118,0.000104174054,0.0000699853,0.000059687838,0.0000058318706,0.000104436695,0.00006937973,0.00008045626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005018026,0.000039233488,0.00006131394,0.000034722445,0.000011605389,0.000006982611,0.00002986571,0.0000055673236,0.9981103,0.00013341423,0.00047351173,0.0010432791],"study_design_scores_gemma":[0.000688974,0.000232004,0.000016499507,0.00004780641,0.0000070075944,0.000002116477,0.000106779444,0.000019967954,0.9799799,0.0005660816,0.018067973,0.0002649156],"about_ca_topic_score_codex":0.000012226636,"about_ca_topic_score_gemma":0.000003780709,"teacher_disagreement_score":0.018130448,"about_ca_system_score_codex":0.000019714438,"about_ca_system_score_gemma":0.00009056497,"threshold_uncertainty_score":0.87842107},"labels":[],"label_agreement":null},{"id":"W2507802242","doi":"10.1074/jbc.m116.749119","title":"Pharmacological Chaperones of the Dopamine Transporter Rescue Dopamine Transporter Deficiency Syndrome Mutations in Heterologous Cells","year":2016,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science","keywords":"Dopamine transporter; Dopamine; Transporter; Biology; Pharmacology; COPII; Chemical chaperone; Endoplasmic reticulum; Cell biology; Chemistry; Gene; Golgi apparatus; Genetics; Endocrinology; Unfolded protein response; Dopaminergic; Secretory pathway","score_opus":0.014726378604770968,"score_gpt":0.23716490534569507,"score_spread":0.2224385267409241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2507802242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980021,0.00048192445,0.0008629953,0.00029326847,0.00014944057,0.000098693636,0.00003898555,0.0000039524607,0.00006864379],"genre_scores_gemma":[0.9990811,0.00033618457,0.00023839819,0.000093467395,0.000117591,0.0000062793874,0.000008946956,0.000009593717,0.000108444525],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985037,0.00007127048,0.00070993794,0.0002506114,0.00019440298,0.0002700671],"domain_scores_gemma":[0.9993182,0.00004271243,0.00028714185,0.00016111184,0.00009853997,0.000092315175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039076083,0.00018666004,0.00033994298,0.000027444348,0.000040623258,0.0000061088103,0.00045000826,0.00029303652,0.00047827527],"category_scores_gemma":[0.000049275168,0.000087635344,0.0003017442,0.00010498097,0.00024129447,0.000007912251,0.00003803127,0.00020356894,0.0000011594686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018717187,0.00021340956,0.0035597358,0.000018379042,0.000029828925,0.0000585774,0.000016536795,0.00006833299,0.9951819,0.000002547266,0.000014126356,0.00064945087],"study_design_scores_gemma":[0.0010378668,0.00057054986,0.010641406,0.00005481487,0.000033318833,0.0003127934,0.000042437892,0.0000043924783,0.9867229,0.000066361004,0.00037559256,0.00013755687],"about_ca_topic_score_codex":0.0000018301159,"about_ca_topic_score_gemma":0.0000018451798,"teacher_disagreement_score":0.008458994,"about_ca_system_score_codex":0.000020053003,"about_ca_system_score_gemma":0.000045334178,"threshold_uncertainty_score":0.5236779},"labels":[],"label_agreement":null},{"id":"W2514125340","doi":"10.1038/nature19424","title":"Designing the ideal opioid","year":2016,"lang":"en","type":"letter","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Opioid; Opium; Opioid receptor; Morphine; Pharmacology; Agonist; Drug discovery; Receptor; Medicine; Chemistry; Internal medicine; Biochemistry","score_opus":0.0067461094788458876,"score_gpt":0.23476020207846288,"score_spread":0.228014092599617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2514125340","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014033468,0.027016876,0.010253365,0.9485397,0.005043124,0.00067013036,0.00016080412,0.00006174624,0.0068509313],"genre_scores_gemma":[0.005692802,0.00036302858,0.001055916,0.95416296,0.02631681,0.00003188511,0.00045255895,0.00008376187,0.011840304],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998866,0.000079575264,0.0001309462,0.00037591884,0.00023028551,0.00031727416],"domain_scores_gemma":[0.9993468,0.000029469109,0.000097866534,0.00042547873,0.000074203635,0.00002618687],"candidate_categories":["research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0001909151,0.00022853211,0.00014927366,0.000025446147,0.0001205809,0.00004594965,0.0004686896,0.005608823,0.00020643308],"category_scores_gemma":[0.000052271433,0.00012446559,0.00016892643,0.000036173147,0.000037772046,0.0000012401349,0.0001031382,0.0037105163,0.000035213583],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000052613054,8.1905995e-7,0.0000025860834,0.000010738659,0.000036779264,0.000013960599,0.0000067326496,3.4052422e-7,0.24992557,0.000022760818,0.7486145,0.0013599355],"study_design_scores_gemma":[0.00008735444,0.0000376271,0.0000014281159,0.000034524375,0.00001567179,0.000015184578,0.0000045218662,5.3456074e-7,0.2037818,0.00034147722,0.7955158,0.00016410225],"about_ca_topic_score_codex":0.0000028230886,"about_ca_topic_score_gemma":0.0000010164857,"teacher_disagreement_score":0.046901252,"about_ca_system_score_codex":0.00001241937,"about_ca_system_score_gemma":0.00007686065,"threshold_uncertainty_score":0.99858797},"labels":[],"label_agreement":null},{"id":"W2518980153","doi":"10.1021/acschemneuro.6b00230","title":"Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M<sub>1</sub>PAM VU6004256","year":2016,"lang":"en","type":"article","venue":"ACS Chemical Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Mental Health; Canadian Institutes of Health Research; William K. Warren Foundation","keywords":"Neuroscience; NMDA receptor; Prefrontal cortex; Allosteric modulator; Long-term potentiation; Agonist; Muscarinic acetylcholine receptor M1; Glutamate receptor; Psychology; Schizophrenia (object-oriented programming); Sigma-1 receptor; Receptor; Cognition; Medicine; Internal medicine; Psychiatry","score_opus":0.011195197776209682,"score_gpt":0.2029406878770287,"score_spread":0.19174549010081904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2518980153","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918644,0.000036544167,0.007464794,0.0001054394,0.00019312621,0.0002218847,0.00008960618,0.000010788137,0.000013459471],"genre_scores_gemma":[0.9990505,0.00014609318,0.00026376426,0.00036253306,0.000037656922,0.000030681094,0.000017370674,0.00001840575,0.000072989074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985536,0.00003463108,0.00029388792,0.0005221691,0.00027811676,0.0003175918],"domain_scores_gemma":[0.9993423,0.000029250677,0.00016914969,0.00030820433,0.00005541746,0.00009568236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015184074,0.00016962872,0.00015653291,0.000027683067,0.000052674335,0.000013901499,0.0003756305,0.0001397091,0.0000064382843],"category_scores_gemma":[0.00028895502,0.00011054038,0.00006949615,0.00016617999,0.00020614068,0.0000139908925,0.0001556368,0.00010152649,0.000004113068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006134684,0.000115806295,0.00034123575,0.000005571821,0.0000026312346,3.9902542e-7,0.000014063773,0.00007066821,0.99830675,0.0000019897827,0.0004926877,0.0005868678],"study_design_scores_gemma":[0.0007262452,0.00014222079,0.0009143439,0.00002763021,0.000004488053,0.0000056853573,0.00001565376,0.0017516752,0.9960734,0.00002739382,0.00016180669,0.00014941969],"about_ca_topic_score_codex":0.000007042911,"about_ca_topic_score_gemma":0.000002928596,"teacher_disagreement_score":0.0072010295,"about_ca_system_score_codex":0.000033002372,"about_ca_system_score_gemma":0.00006124066,"threshold_uncertainty_score":0.4507706},"labels":[],"label_agreement":null},{"id":"W2519198844","doi":"10.1124/mol.116.105940","title":"A Pluridimensional View of Biased Agonism","year":2016,"lang":"en","type":"review","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Functional selectivity; Effector; G protein-coupled receptor; Computational biology; Signal transduction; Biology; Signaling proteins; Drug discovery; Identification (biology); Receptor; Phenotype; Subcellular localization; Ligand (biochemistry); Agonism; Cell signaling; Cell biology; Neuroscience; Bioinformatics; Genetics; Gene; Political science; Ecology","score_opus":0.02400689174464857,"score_gpt":0.33999626678133876,"score_spread":0.31598937503669017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2519198844","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022226006,0.9953864,0.0023782242,0.000031471012,0.0009229225,0.00062207144,0.0001140867,0.0000150587975,0.000307458],"genre_scores_gemma":[0.00017517184,0.9975859,0.0005585341,0.00034928828,0.00037995644,0.0001527465,0.0003068562,0.00010598009,0.0003855968],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99752367,0.00046516265,0.0006981699,0.00067972427,0.00020603734,0.00042722776],"domain_scores_gemma":[0.9988187,0.000047108653,0.00046169,0.0004076665,0.0001200062,0.00014480777],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003137526,0.000495836,0.0012919299,0.00015521403,0.00005115629,0.0000080257205,0.00046794975,0.0006240773,0.0013384334],"category_scores_gemma":[0.000033100674,0.00037911226,0.0008492947,0.00013854644,0.00012581721,0.0000019664599,0.00028218777,0.00021249622,0.00009469162],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019511554,0.00006476101,4.529766e-8,0.0017652506,0.00052940415,0.000048255122,0.0000026345745,0.0000019913032,0.6832725,0.00018029156,0.0025107707,0.3116046],"study_design_scores_gemma":[0.00040117512,0.00016991344,2.1026667e-8,0.0010089502,0.00038405586,0.00006130698,6.5317187e-7,0.0000012462033,0.2510994,0.000040394192,0.7465286,0.00030425217],"about_ca_topic_score_codex":0.000002243774,"about_ca_topic_score_gemma":2.3428177e-7,"teacher_disagreement_score":0.74401784,"about_ca_system_score_codex":0.000029680854,"about_ca_system_score_gemma":0.0004741388,"threshold_uncertainty_score":0.99986607},"labels":[],"label_agreement":null},{"id":"W2520249977","doi":"10.1038/tp.2016.157","title":"Evidence that COMT genotype and proline interact on negative-symptom outcomes in schizophrenia and bipolar disorder","year":2016,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Research Resources; National Center for Advancing Translational Sciences; National Institute of Mental Health; York University","keywords":"Proline dehydrogenase; Schizophrenia (object-oriented programming); Proline; Bipolar disorder; Catechol-O-methyl transferase; Psychology; Positive and Negative Syndrome Scale; Psychosis; Psychiatry; Internal medicine; Genotype; Allele; Medicine; Genetics; Mood; Gene; Biology; Amino acid","score_opus":0.019191960834047294,"score_gpt":0.2691070925606815,"score_spread":0.2499151317266342,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2520249977","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989094,0.0043685585,0.003936194,0.0021999418,0.00012360551,0.0001543811,0.000015891907,0.000007655652,0.00009975959],"genre_scores_gemma":[0.99573237,0.0004655882,0.0033088238,0.00017054814,0.000071686154,0.000008225539,0.0000067325486,0.000018659362,0.00021736533],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99939173,0.00003549849,0.00012534074,0.00024728055,0.00009221271,0.00010794566],"domain_scores_gemma":[0.99975294,0.00004693716,0.000046845646,0.000095344585,0.000013854254,0.00004407397],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009107452,0.00011751341,0.000104635146,0.00005074466,0.00003773066,0.000012623406,0.000056024586,0.000072426665,0.00012736242],"category_scores_gemma":[0.000023887878,0.000079741796,0.00003080601,0.000033794848,0.000041325035,0.000010657645,0.000013238127,0.0000535138,0.0000055287996],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00064529554,0.00008873589,0.8055298,0.000023117438,0.00005241456,4.3160648e-7,0.00007707498,0.00001715145,0.15215336,0.003203025,0.000053533135,0.038156066],"study_design_scores_gemma":[0.003952657,0.00051987555,0.9643104,0.0004252713,0.000022802915,0.000008772939,0.000037812104,0.00015876176,0.01855825,0.0076981992,0.0038565623,0.0004505993],"about_ca_topic_score_codex":0.000010555361,"about_ca_topic_score_gemma":0.00016181705,"teacher_disagreement_score":0.15878063,"about_ca_system_score_codex":0.0000025474126,"about_ca_system_score_gemma":0.000028852895,"threshold_uncertainty_score":0.3251776},"labels":[],"label_agreement":null},{"id":"W2520464369","doi":"","title":"Novel regulatory mechanisms of D1 dopamine receptor maturation and internalization.","year":2008,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Internalization; Dopamine; Neuroscience; Dopamine receptor; Dopamine receptor D1; Dopamine receptor D2; Biology; Cell biology; Receptor; Genetics","score_opus":0.007349129449280394,"score_gpt":0.21413521465927002,"score_spread":0.20678608520998962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2520464369","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9315348,0.0025423213,0.059299886,0.000027373022,0.0005107113,0.00027419702,0.000061350474,0.000015174159,0.0057341647],"genre_scores_gemma":[0.9702235,0.0026775778,0.0104655,0.000008194729,0.00006862369,4.524473e-7,0.0012822945,0.000027467295,0.015246379],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999299,0.000024913477,0.00013253816,0.00027052345,0.00017110411,0.00010195761],"domain_scores_gemma":[0.9991767,0.0000051368174,0.00036654444,0.00020061793,0.000198453,0.00005255675],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00007592412,0.00016015595,0.00025074574,0.00003653272,0.00007595292,0.0000049168248,0.00016053022,0.00031770233,0.0017259938],"category_scores_gemma":[0.0000142598265,0.00019966856,0.00010208521,0.000026263198,0.000043351018,0.000016777178,0.000047403846,0.000058759055,0.0000011176957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003080599,0.000035186295,0.0000067835012,0.00010990649,0.000088262896,6.723979e-7,0.0010841211,0.000010545741,0.99409485,0.0008400613,0.00030663525,0.0031149134],"study_design_scores_gemma":[0.0010656847,0.0005379265,0.0069595966,0.00025559313,0.00012502712,0.000010224122,0.011296807,0.00019778323,0.97728544,0.000052422765,0.0017722084,0.00044128989],"about_ca_topic_score_codex":0.0049889996,"about_ca_topic_score_gemma":0.005034558,"teacher_disagreement_score":0.048834387,"about_ca_system_score_codex":0.00003918688,"about_ca_system_score_gemma":0.00006778055,"threshold_uncertainty_score":0.9991866},"labels":[],"label_agreement":null},{"id":"W2527934634","doi":"10.1091/mbc.e16-04-0224","title":"Regulation of GPCR expression through an interaction with CCT7, a subunit of the CCT/TRiC complex","year":2016,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Biology; Cell biology; Receptor; Protein subunit; HEK 293 cells; Gene isoform; Chaperone (clinical); Chaperonin; Signal transduction; Biochemistry; Protein folding","score_opus":0.01398249192819249,"score_gpt":0.24960435777917325,"score_spread":0.23562186585098077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2527934634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96990293,0.00015328114,0.02918435,0.00011018429,0.000113586524,0.00016907397,0.000013002194,0.0000027734977,0.0003508018],"genre_scores_gemma":[0.998095,0.000029831013,0.0016544175,0.000046459027,0.000024211255,0.000004619101,0.000018941755,0.00001281094,0.00011370848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991264,0.0002455603,0.00022813784,0.00019432454,0.000092986025,0.00011263912],"domain_scores_gemma":[0.99897224,0.00001536551,0.0003658077,0.00050625263,0.00012299827,0.000017317418],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013446948,0.0001078188,0.00015257302,0.000023661025,0.000044383574,0.0000019815457,0.0003145938,0.0001329755,0.000051013172],"category_scores_gemma":[0.000029674073,0.00004991279,0.00011548932,0.000094617164,0.00019250977,0.000006241127,0.00012603376,0.000048817026,5.031841e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012558968,0.000064230684,0.00064971595,0.000016501894,0.000021044798,7.499242e-8,0.000049426977,0.00013528892,0.99819136,0.00029990906,0.00004225807,0.00040461618],"study_design_scores_gemma":[0.0004778682,0.0003964626,0.00087089103,0.000057572837,0.000023409253,0.000003751362,0.000049965736,0.000031428375,0.996115,0.0008176191,0.0010833113,0.00007271335],"about_ca_topic_score_codex":0.000034053588,"about_ca_topic_score_gemma":0.000007005766,"teacher_disagreement_score":0.028192054,"about_ca_system_score_codex":0.0000069855587,"about_ca_system_score_gemma":0.000030217268,"threshold_uncertainty_score":0.20353845},"labels":[],"label_agreement":null},{"id":"W2529484558","doi":"10.1182/blood.v126.23.4267.4267","title":"G Protein-Coupled Receptor 56 As a Potential Regulator of Normal and Leukemic Stem Cells","year":2015,"lang":"en","type":"article","venue":"Blood","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Princess Margaret Cancer Centre; Hospital for Sick Children; University Health Network; McGill University","funders":"","keywords":"Biology; Stem cell; Haematopoiesis; Progenitor cell; Myeloid leukemia; Myeloid; Leukemia; CD34; Cancer research; Regulator; Cell biology; Immunology; Molecular biology; Gene; Genetics","score_opus":0.007706821041294473,"score_gpt":0.19928281490347502,"score_spread":0.19157599386218055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2529484558","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980526,0.0008928493,0.0004796044,0.000014833931,0.00012592268,0.0002252293,0.00001029577,0.000009469389,0.00018922208],"genre_scores_gemma":[0.9966599,0.000029931949,0.0016802843,0.00002386696,0.00024234639,0.000015236723,0.0000160256,0.000020133359,0.0013123245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921125,0.000035143737,0.00018914574,0.00024295849,0.00014748525,0.0001740042],"domain_scores_gemma":[0.9994779,0.0000021420492,0.000098389064,0.00019810583,0.00009567468,0.00012774674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018863333,0.00012089214,0.00014994323,0.000025143076,0.00003211593,0.000016367274,0.00010903725,0.00014493974,0.000047829035],"category_scores_gemma":[0.0000120678005,0.0001117085,0.000073758754,0.00004130158,0.000039261733,0.000004075051,0.000087468085,0.000053821044,0.000009874891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009668476,0.00007117215,0.0000418657,0.000021351758,0.000057276695,0.000002381477,0.000052030176,0.000016687432,0.99901533,0.000064064014,0.00014981817,0.00041134443],"study_design_scores_gemma":[0.0016535799,0.0005713537,0.000009623668,0.00001833562,0.000038019774,0.000018488723,0.00015290143,0.00006818448,0.9960455,0.000053962904,0.0012318894,0.00013819378],"about_ca_topic_score_codex":0.000030472465,"about_ca_topic_score_gemma":0.0000017359836,"teacher_disagreement_score":0.0029698566,"about_ca_system_score_codex":0.0000056180393,"about_ca_system_score_gemma":0.0001195969,"threshold_uncertainty_score":0.45553404},"labels":[],"label_agreement":null},{"id":"W2531536521","doi":"10.1161/circresaha.116.309972","title":"The Louis and Artur Lucian Award in Cardiovascular Diseases at McGill University","year":2016,"lang":"en","type":"article","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McGill University","funders":"","keywords":"Medicine; St louis; Art; Gerontology; Art history","score_opus":0.026569697928554764,"score_gpt":0.27043265028496255,"score_spread":0.24386295235640779,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2531536521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971566,0.0014947867,0.00044019474,0.00040378736,0.000045014665,0.00014874015,0.000031652504,0.000004754738,0.0002744688],"genre_scores_gemma":[0.9981448,0.0007778412,0.000011104088,0.000009958268,0.00005626205,0.000003242715,0.000009651397,0.0000069825946,0.00098013],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990679,0.00021670928,0.00006654068,0.00023831685,0.00021595148,0.00019458873],"domain_scores_gemma":[0.99952346,0.000055640045,0.000013199399,0.00024361943,0.00009499661,0.00006908748],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004960477,0.00005128233,0.00006823469,0.00004725536,0.00031425455,0.000013904619,0.00009719281,0.000064450214,0.000022258828],"category_scores_gemma":[0.00012973687,0.000034208348,0.00006546728,0.00009827703,0.00007842362,0.000004626704,0.0001271729,0.00004663513,0.000010847283],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001725519,0.000032534153,0.060721632,0.000021410282,0.00015013314,0.000023293574,0.000052232022,0.00040971162,0.8698859,0.0014637022,0.0011899744,0.065876886],"study_design_scores_gemma":[0.0018405765,0.00014073572,0.19776398,0.0000613415,0.000025606829,0.000011767274,0.00036975963,0.0005014587,0.078375004,0.0017373828,0.71882504,0.00034736216],"about_ca_topic_score_codex":0.00006770305,"about_ca_topic_score_gemma":0.00010180696,"teacher_disagreement_score":0.79151094,"about_ca_system_score_codex":0.00007582618,"about_ca_system_score_gemma":0.000026969847,"threshold_uncertainty_score":0.24170236},"labels":[],"label_agreement":null},{"id":"W2531923638","doi":"10.1021/acs.jmedchem.6b01194","title":"Design and Discovery of Functionally Selective Serotonin 2C (5-HT<sub>2C</sub>) Receptor Agonists","year":2016,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Institute of Mental Health","keywords":"Chemistry; Functional selectivity; Agonist; Arrestin; Serotonin; 5-HT2C receptor; Serotonergic; 5-HT receptor; Receptor; Pharmacology; Desensitization (medicine); G protein-coupled receptor; Partial agonist; Intrinsic activity; Signal transduction; Biochemistry; Biology","score_opus":0.0075907545780319,"score_gpt":0.21746389754267756,"score_spread":0.20987314296464565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2531923638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9503779,0.001508241,0.047365405,0.00029407468,0.00020657356,0.00008992363,0.000009544596,0.0000032869355,0.00014505019],"genre_scores_gemma":[0.99603134,0.0010793848,0.0016411497,0.000075653,0.000782579,0.000005109606,0.000006976936,0.000022348178,0.00035547127],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986475,0.00006415594,0.00047433755,0.00022800323,0.0003795727,0.00020641618],"domain_scores_gemma":[0.9987826,0.00007609665,0.000505487,0.00014318644,0.00033994435,0.00015273214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006767543,0.00018601009,0.00031446826,0.000035445057,0.000054067892,0.000015547397,0.00016979786,0.00020291375,0.00006926039],"category_scores_gemma":[0.0002610492,0.00012448327,0.00012754371,0.00006835957,0.0001373566,0.000019851112,0.00005050138,0.00018355998,0.0000012672839],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077232067,0.00005449105,0.00031936885,0.00005945568,0.00015932115,0.000009967678,0.000037372396,0.000020108873,0.99362725,0.0000076097535,0.001795241,0.0031374847],"study_design_scores_gemma":[0.0012130267,0.0007045075,0.00022986595,0.00027117017,0.00005775118,0.00031973983,0.000103482074,0.000007229254,0.9956171,0.00018636855,0.0011394825,0.0001502843],"about_ca_topic_score_codex":0.0000012191837,"about_ca_topic_score_gemma":2.5493293e-7,"teacher_disagreement_score":0.045724254,"about_ca_system_score_codex":0.000047398178,"about_ca_system_score_gemma":0.00031113334,"threshold_uncertainty_score":0.5076281},"labels":[],"label_agreement":null},{"id":"W2532962724","doi":"10.1016/j.bmc.2016.10.010","title":"Design and synthesis of novel N-sulfonyl-2-indoles that behave as 5-HT6 receptor ligands with significant selectivity for D3 over D2 receptors","year":2016,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; 5-HT6 receptor; Dopamine receptor D2; Neurocognitive; Receptor; Sulfonyl; Selectivity; Dopamine receptor D3; Schizophrenia (object-oriented programming); Pharmacology; Stereochemistry; 5-HT receptor; Neuroscience; Cognition; Psychology; Biochemistry; Psychiatry; Serotonin; Organic chemistry; Catalysis; Medicine","score_opus":0.016063178511289588,"score_gpt":0.23252179934269432,"score_spread":0.21645862083140474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2532962724","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9406074,0.00039669636,0.05815829,0.00020239747,0.00011465916,0.00037303907,0.000053030475,0.000024293375,0.00007018125],"genre_scores_gemma":[0.9948848,0.0003354084,0.0036690696,0.000058079753,0.0003447199,0.00007873685,0.000025647521,0.00006624957,0.00053731643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982759,0.000031716158,0.00031018577,0.000662422,0.0003222945,0.0003974815],"domain_scores_gemma":[0.9987938,0.00020433172,0.00027133926,0.0003473215,0.00016600575,0.00021720793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005427286,0.0003484746,0.00041865974,0.000033921628,0.00010407374,0.000017842684,0.00023905907,0.0003466534,0.00027922084],"category_scores_gemma":[0.0003649963,0.0002319692,0.000096969095,0.00010700951,0.0002407465,0.000011101074,0.0000707628,0.00010616564,0.0000017573275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00068698585,0.00015120245,0.0007427952,0.00012063474,0.00013875078,0.0000014221439,0.000055867273,7.502609e-7,0.9941063,0.000010279865,0.0005879415,0.0033970873],"study_design_scores_gemma":[0.0017773885,0.00067229744,0.000105644394,0.00030946927,0.00012315155,0.00003736503,0.0002343063,0.000015049109,0.9952709,0.000023886081,0.0010718438,0.00035867744],"about_ca_topic_score_codex":0.00002127415,"about_ca_topic_score_gemma":0.0000019187105,"teacher_disagreement_score":0.054489218,"about_ca_system_score_codex":0.00004938024,"about_ca_system_score_gemma":0.00026029153,"threshold_uncertainty_score":0.94594294},"labels":[],"label_agreement":null},{"id":"W253908916","doi":"10.1093/oxfordhb/9780199753888.013.004","title":"Genetic Tools in the Erasure of Emotional Memory","year":2013,"lang":"en","type":"book","venue":"Oxford University Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Psychology; Recall; Psychopathology; Cognitive psychology; Developmental psychology; Clinical psychology","score_opus":0.019279535782203604,"score_gpt":0.19911064158299757,"score_spread":0.17983110580079398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W253908916","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03536183,0.00029857998,0.0006998837,0.000008477542,0.00013189929,0.00048411544,0.00009761226,0.00000672168,0.9629109],"genre_scores_gemma":[0.01286437,0.000245812,0.0005705604,0.00007414264,0.00021484692,0.0000026593939,0.00016082678,0.000025418518,0.98584133],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99913716,0.000089778136,0.0001517149,0.00026724933,0.00019400092,0.00016011727],"domain_scores_gemma":[0.9993654,0.000021746422,0.00014244312,0.00035052016,0.00008399845,0.000035880214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011051219,0.00017822451,0.00019459904,0.000055100245,0.00005382581,0.0000195859,0.00049901183,0.0003561842,0.00006081232],"category_scores_gemma":[0.000008182596,0.00015834549,0.0001529899,0.000008522827,0.000079565914,0.0000030677172,0.00015180171,0.00019812604,4.435373e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001015681,0.00047206486,0.00026854433,0.0016369383,0.0018397253,0.00036541527,0.0028016602,0.0025801307,0.42286342,0.22361661,0.25539997,0.08713982],"study_design_scores_gemma":[0.00038386902,0.00012485645,0.00013741895,0.000071866365,0.00004616919,0.000008018052,0.00009061201,0.00002052068,0.008267743,0.00020987117,0.9904279,0.00021112637],"about_ca_topic_score_codex":0.000026200496,"about_ca_topic_score_gemma":0.000012650132,"teacher_disagreement_score":0.73502797,"about_ca_system_score_codex":0.000027254164,"about_ca_system_score_gemma":0.00017393405,"threshold_uncertainty_score":0.64571416},"labels":[],"label_agreement":null},{"id":"W2543825232","doi":"10.1016/j.lfs.2016.10.027","title":"Alterations in ventral and dorsal striatal allosteric A2AR-D2R receptor-receptor interactions after amphetamine challenge: Relevance for schizophrenia","year":2016,"lang":"en","type":"article","venue":"Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Medicinska Forskningsrådet; Hjärnfonden; AFA Försäkring","keywords":"Amphetamine; Quinpirole; Striatum; Dopamine receptor D2; Ventral striatum; Chemistry; CGS-21680; Agonist; Dopamine; Allosteric regulation; Adenosine A2A receptor; Pharmacology; Internal medicine; Receptor; Biology; Medicine; Adenosine receptor; Biochemistry","score_opus":0.017265981359549123,"score_gpt":0.2721082011713613,"score_spread":0.2548422198118122,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2543825232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99144655,0.0010674603,0.004918755,0.0014481259,0.0007378369,0.00023387137,0.00008015251,0.000010611362,0.000056614426],"genre_scores_gemma":[0.99274445,0.0004902707,0.0056861904,0.00011792041,0.00041062685,0.000115949835,0.000025353862,0.000010716396,0.0003985502],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890095,0.000045833793,0.00022975552,0.00042929314,0.000120754834,0.00027339175],"domain_scores_gemma":[0.9995997,0.00006321103,0.000075996046,0.00013125275,0.000042922704,0.00008691495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025127013,0.00013236709,0.00012723048,0.00006480668,0.00014329975,0.000052821768,0.00015435822,0.00006793721,0.00017368629],"category_scores_gemma":[0.00022032254,0.000095210395,0.000056314777,0.00010684627,0.0001494532,0.00004146369,0.00006905885,0.000049409995,0.00001139989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032849243,0.000060818897,0.0007458368,0.00001154363,0.000017248825,3.750242e-7,0.0001365842,0.000017140843,0.9835361,0.0004621836,0.00052788545,0.014155756],"study_design_scores_gemma":[0.0054644146,0.0030754115,0.003610234,0.0004625074,0.000040530747,0.00001744803,0.0010138521,0.00086822186,0.79041255,0.0015401663,0.19218165,0.0013130252],"about_ca_topic_score_codex":0.000010949963,"about_ca_topic_score_gemma":0.00010806957,"teacher_disagreement_score":0.1931236,"about_ca_system_score_codex":0.000014008741,"about_ca_system_score_gemma":0.00007872592,"threshold_uncertainty_score":0.3882567},"labels":[],"label_agreement":null},{"id":"W2549130285","doi":"10.1007/978-3-319-41523-9_3","title":"7TM Domain Structure of Adhesion GPCRs","year":2016,"lang":"en","type":"review","venue":"Handbook of experimental pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"G protein-coupled receptor; Protein Data Bank (RCSB PDB); Glucagon receptor; Transmembrane domain; Salt bridge; Chemistry; Biology; Biochemistry; Receptor; Glucagon","score_opus":0.02025319383160225,"score_gpt":0.3460843897016434,"score_spread":0.32583119587004117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2549130285","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00300699,0.99508595,0.00018211178,0.0000021391465,0.0008334152,0.00052781764,0.00017067582,0.0000063375646,0.00018455692],"genre_scores_gemma":[0.0030042746,0.99506646,0.0009395855,0.000038851,0.0004893289,0.000038978684,0.0001690194,0.0000606349,0.00019287782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982923,0.00020176341,0.000637072,0.00044966995,0.00014819292,0.00027094685],"domain_scores_gemma":[0.9990132,0.000028140656,0.00056266744,0.0002523667,0.00005031979,0.00009330362],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000092050555,0.00038246726,0.0011002773,0.00010415918,0.000041947093,0.000003774739,0.0003602304,0.000507315,0.0028695702],"category_scores_gemma":[0.000005695416,0.0002805109,0.0004843679,0.00005511667,0.00017497124,0.0000034315074,0.00023088754,0.00012463958,0.000009995249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079106554,0.00007500484,2.6154385e-7,0.00090789783,0.000248464,0.0000032118644,0.000030748502,2.3177464e-7,0.95821774,0.000045600627,0.0018509727,0.038540736],"study_design_scores_gemma":[0.0004370688,0.00035158944,1.2114962e-8,0.0013232903,0.000083214574,0.000015452633,0.000015522497,1.16286074e-7,0.5883378,0.000018356757,0.4092564,0.00016117177],"about_ca_topic_score_codex":0.000003087162,"about_ca_topic_score_gemma":3.2748514e-7,"teacher_disagreement_score":0.40740544,"about_ca_system_score_codex":0.000035706616,"about_ca_system_score_gemma":0.00015895715,"threshold_uncertainty_score":0.9999647},"labels":[],"label_agreement":null},{"id":"W2549275642","doi":"10.1016/j.neubiorev.2016.10.024","title":"A review of molecular genetic studies of neurocognitive deficits in schizophrenia","year":2016,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research","keywords":"Neurocognitive; Endophenotype; Schizophrenia (object-oriented programming); Psychology; Cognition; Neuroscience; DISC1; Catechol-O-methyl transferase; Psychosis; Executive functions; Psychiatry; Allele; Genetics; Gene; Biology","score_opus":0.11224494644281843,"score_gpt":0.4081255406234556,"score_spread":0.29588059418063717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2549275642","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010537736,0.99640435,0.000102739614,0.0000012824516,0.00030893934,0.0020218277,0.00008110555,0.0000052839114,0.000020721209],"genre_scores_gemma":[0.000121000536,0.99867123,0.00052132807,0.00025434993,0.000045192308,0.00029297656,0.00002067295,0.00005341172,0.00001982365],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99588543,0.0005212436,0.0018903477,0.000954923,0.00033783863,0.0004102097],"domain_scores_gemma":[0.99744546,0.0000054448087,0.001460104,0.00075654633,0.00022387665,0.00010857093],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00082934357,0.0006025362,0.0027419906,0.00021730273,0.000036880985,0.0000104799865,0.00077104074,0.00023370584,0.00003082714],"category_scores_gemma":[0.000986695,0.00040483178,0.0009289948,0.0007067496,0.00034110236,0.000009304475,0.00035607442,0.00022264142,0.000011337364],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000051617767,0.000062221814,0.000003600726,0.033044487,7.074838e-7,0.000011119004,0.0000036657527,6.996764e-8,0.0865576,0.000010004867,0.00009669315,0.8802047],"study_design_scores_gemma":[0.00014102233,0.00043043957,0.0000035461935,0.1539869,0.00028935168,0.000033731696,0.000003152067,1.11903994e-7,0.0028499095,0.000008882359,0.8419142,0.00033876582],"about_ca_topic_score_codex":0.000003989353,"about_ca_topic_score_gemma":0.0000019003744,"teacher_disagreement_score":0.8798659,"about_ca_system_score_codex":0.000026462032,"about_ca_system_score_gemma":0.0002991413,"threshold_uncertainty_score":0.9998404},"labels":[],"label_agreement":null},{"id":"W2550153817","doi":"10.5334/1750-2187-11-5","title":"MAGI Proteins Regulate the Trafficking and Signaling of Corticotropin-Releasing Factor Receptor 1 via a Compensatory Mechanism","year":2016,"lang":"en","type":"article","venue":"Journal of Molecular Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Western University","funders":"","keywords":"PDZ domain; Internalization; Biology; Cell biology; Gene knockdown; HEK 293 cells; Receptor; Signal transduction; Scaffold protein; Immunoprecipitation; Biochemistry; Gene","score_opus":0.009624846295814109,"score_gpt":0.22075027495215488,"score_spread":0.21112542865634076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2550153817","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73950666,0.0020713257,0.25782806,0.00016484266,0.00020201424,0.000208098,0.0000053753797,0.0000067370784,0.0000068770246],"genre_scores_gemma":[0.9902597,0.00037309603,0.008925747,0.00010885838,0.00024573415,0.0000043529544,0.0000019470008,0.00005930787,0.000021238553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99766743,0.00028481756,0.0008845531,0.00031182458,0.0004975854,0.00035380805],"domain_scores_gemma":[0.9980926,0.00007704432,0.0009883702,0.00028706688,0.00039526352,0.00015963553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003300431,0.00028493706,0.00045007377,0.00012387513,0.00015536768,0.000052977728,0.00034390844,0.00018729841,0.000084759464],"category_scores_gemma":[0.00017309726,0.0001787718,0.0003201657,0.00011735408,0.00013464227,0.000022926157,0.000104833256,0.00022181621,0.0000015219217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017904477,0.000038658458,0.000058146434,0.000043664862,0.00020951024,0.000020226773,0.00017374936,0.00036002326,0.9881305,0.00035273208,0.000008602385,0.01042515],"study_design_scores_gemma":[0.00095904066,0.0006058896,0.00005968779,0.00051999633,0.00008120838,0.0001504503,0.0001712871,0.00014794579,0.9959984,0.0007512952,0.00030378485,0.00025104737],"about_ca_topic_score_codex":0.000005682899,"about_ca_topic_score_gemma":7.4664314e-7,"teacher_disagreement_score":0.25075305,"about_ca_system_score_codex":0.00003654069,"about_ca_system_score_gemma":0.00013121983,"threshold_uncertainty_score":0.7290103},"labels":[],"label_agreement":null},{"id":"W2552797469","doi":"10.1016/j.cellsig.2016.11.015","title":"VCP/p97 regulates β2AR quality control during receptor biosynthesis","year":2016,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Endoplasmic-reticulum-associated protein degradation; Receptor; Cell biology; Endoplasmic reticulum; Proteasome; Biology; Chemistry; Unfolded protein response; Biochemistry","score_opus":0.010134562623829097,"score_gpt":0.21710024771325104,"score_spread":0.20696568508942195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2552797469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.916791,0.0011642914,0.08106319,0.0001745401,0.00032736492,0.00020265598,0.000029417433,0.000056977966,0.00019052024],"genre_scores_gemma":[0.99589115,0.00021385912,0.0014193706,0.00008383266,0.00070704956,0.000023832681,0.000029099168,0.00006576881,0.001566033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978749,0.00020967313,0.00048329507,0.00065816997,0.00026268847,0.00051122985],"domain_scores_gemma":[0.998946,0.00008881192,0.0002036859,0.0004574247,0.00012434354,0.0001797393],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072731136,0.0002995436,0.00032264664,0.000068291665,0.00022362317,0.000051798543,0.00032264704,0.00028301004,0.00091255235],"category_scores_gemma":[0.00020343199,0.00022696955,0.00027424996,0.00008988591,0.000080288606,0.000011561079,0.000078910016,0.0000932153,0.00009533352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013625882,0.00003582672,0.00045594887,0.000029654708,0.0001059305,0.00000426741,0.00002829851,0.00006547271,0.99691767,0.00022130778,0.00008902284,0.0019103324],"study_design_scores_gemma":[0.00094111584,0.000089363384,0.00008951067,0.000107606626,0.000027948421,0.0000030851959,0.000055955414,0.000043345874,0.9933198,0.00022936027,0.004683719,0.0004091955],"about_ca_topic_score_codex":0.000010592815,"about_ca_topic_score_gemma":0.000002372832,"teacher_disagreement_score":0.07964382,"about_ca_system_score_codex":0.000037907274,"about_ca_system_score_gemma":0.00004529119,"threshold_uncertainty_score":0.99918085},"labels":[],"label_agreement":null},{"id":"W2553559575","doi":"10.1016/j.coph.2016.10.008","title":"Measuring G protein-coupled receptor signalling in the brain with resonance energy transfer based biosensors","year":2016,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Signalling; Förster resonance energy transfer; In vivo; Signal transduction; Cell biology; Receptor; Biology; Intracellular; Neuroscience; Signalling pathways; Computational biology; Biochemistry; Genetics; Fluorescence","score_opus":0.07384088002037982,"score_gpt":0.3403078889575239,"score_spread":0.2664670089371441,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2553559575","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00047403638,0.9905408,0.0054162475,0.00020161748,0.0020098079,0.0012783011,0.00004684934,0.000014562663,0.00001779576],"genre_scores_gemma":[0.0017133055,0.9951311,0.00010556417,0.000101619,0.0012121161,0.0013478887,0.0002645505,0.00008243387,0.000041452215],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964844,0.0010897664,0.0007355342,0.0008445138,0.00026576486,0.0005800256],"domain_scores_gemma":[0.999214,0.00016274306,0.00019152687,0.0002836668,0.00006686269,0.00008118958],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00094612705,0.0005422027,0.00083339226,0.00026609204,0.00007951161,0.000026798807,0.0006266302,0.00041074524,0.0002547635],"category_scores_gemma":[0.00003689249,0.00033701427,0.0002728207,0.00035853716,0.0001000145,0.0000071565346,0.000051861512,0.00050064764,0.00001012582],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047530694,0.00045639218,0.000007841606,0.007339219,0.00013891225,0.0000109849925,0.00009634734,0.00010055886,0.12078952,0.00034631693,0.002709092,0.8675295],"study_design_scores_gemma":[0.0013840299,0.00023664933,4.003193e-7,0.0089718755,0.000035279732,0.000008555823,0.000009578246,0.00007321606,0.016484728,0.000011051734,0.9723019,0.0004827469],"about_ca_topic_score_codex":0.000008328316,"about_ca_topic_score_gemma":0.000007331949,"teacher_disagreement_score":0.9695928,"about_ca_system_score_codex":0.00008835911,"about_ca_system_score_gemma":0.000424531,"threshold_uncertainty_score":0.9999082},"labels":[],"label_agreement":null},{"id":"W2555195584","doi":"10.3389/fphys.2016.00525","title":"Systematic Characterization of Dynamic Parameters of Intracellular Calcium Signals","year":2016,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Shriners Hospitals for Children - Canada; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Amplitude; Time constant; Duty cycle; SIGNAL (programming language); Standard deviation; Biological system; Algorithm; Transient response; Exponential function; Computer science; Transient (computer programming); Signal processing; Rise time; Control theory (sociology); Physics; Mathematics; Statistics; Voltage; Artificial intelligence; Mathematical analysis; Optics; Digital signal processing","score_opus":0.006280506062379144,"score_gpt":0.2146903788760663,"score_spread":0.20840987281368714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2555195584","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86865467,0.0002657039,0.1304967,0.000014055786,0.00034897428,0.00019323669,0.000016943912,0.000002711725,0.000007007683],"genre_scores_gemma":[0.9971424,0.00014722078,0.0025171782,0.000018071472,0.000018481542,0.000021767903,0.000046482604,0.000012493284,0.00007590824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999037,0.0001480552,0.0003949501,0.00020435281,0.00006351213,0.00015212536],"domain_scores_gemma":[0.9994224,0.000016226917,0.00026269368,0.00022403622,0.000050369956,0.000024328161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017541605,0.00010210001,0.0003727712,0.00007825043,0.0000097251805,0.000001373305,0.00014653812,0.00014064932,0.00001749301],"category_scores_gemma":[0.00006386599,0.000073353985,0.00008212338,0.00006753573,0.00008546337,0.0000039647643,0.000035448233,0.000030129184,0.0000011018885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000068911446,0.000032927746,0.00019817574,0.0006545654,0.000058775895,3.351606e-7,0.000032447842,0.000020202917,0.9983102,0.0000307339,0.000020872552,0.0005718596],"study_design_scores_gemma":[0.00030208786,0.00019564587,0.00075006444,0.00042110114,0.000015560125,8.963381e-7,0.000052233438,0.00040434877,0.9972737,0.00048069528,0.000011799554,0.000091889684],"about_ca_topic_score_codex":0.0000036620313,"about_ca_topic_score_gemma":5.128269e-7,"teacher_disagreement_score":0.12848772,"about_ca_system_score_codex":0.0000138887945,"about_ca_system_score_gemma":0.000022977723,"threshold_uncertainty_score":0.2991289},"labels":[],"label_agreement":null},{"id":"W2556587095","doi":"10.3791/54792","title":"Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to &lt;em&gt;S&lt;/em&gt;-citalopram","year":2016,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institute of Mental Health; Howard Hughes Medical Institute; National Institutes of Health; National Science Foundation","keywords":"Citalopram; Serotonin transporter; Serotonin; Transporter; Serotonin Plasma Membrane Transport Proteins; Chemistry; Serotonin Uptake Inhibitors; Serotonin reuptake inhibitor; Biochemistry; Pharmacology; Biology; Receptor; Fluoxetine; Gene","score_opus":0.016548276700639526,"score_gpt":0.32780599756503037,"score_spread":0.31125772086439085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2556587095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9619771,0.00063597644,0.03674961,0.00008148443,0.0001737191,0.0003209285,0.000009864043,0.000004568431,0.00004673959],"genre_scores_gemma":[0.99810123,0.00012937457,0.001192758,0.00011919538,0.000117988435,0.000019217685,0.000013097921,0.00003179587,0.0002753667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984433,0.00013478826,0.000651893,0.00022609044,0.00037649408,0.00016744653],"domain_scores_gemma":[0.99866855,0.000011297807,0.0005140188,0.0002742602,0.00041409547,0.0001177772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037567926,0.00017084258,0.00023125282,0.00006974432,0.00014353266,0.000045293782,0.00025590623,0.00013044901,0.00018691954],"category_scores_gemma":[0.00006970632,0.00010246614,0.00011791965,0.000112315065,0.000053760476,0.000029177738,0.000049480834,0.000043363296,9.5215734e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001274492,0.00013026019,0.00078655547,0.000012693835,0.000052569903,5.8530384e-7,0.0014243657,0.00001394661,0.99641466,0.00021797832,0.000456598,0.0003623066],"study_design_scores_gemma":[0.001291387,0.00030603094,0.0017703249,0.0001608035,0.000022194758,0.0000089640025,0.0003320373,0.0000044113713,0.9899995,0.0002264711,0.0057369308,0.00014095429],"about_ca_topic_score_codex":0.0000012217087,"about_ca_topic_score_gemma":0.0000031851878,"teacher_disagreement_score":0.03612409,"about_ca_system_score_codex":0.00002858857,"about_ca_system_score_gemma":0.00006635376,"threshold_uncertainty_score":0.41784477},"labels":[],"label_agreement":null},{"id":"W2557428787","doi":"10.1210/en.2016-1552","title":"Ligand-biased regulation of PtdIns(3,4,5)P3-dependent signal transduction in GPCR control of pituitary hormone release","year":2016,"lang":"en","type":"article","venue":"Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Signal transduction; G protein-coupled receptor; Effector; Second messenger system; Biology; Cell biology; Receptor; G protein; Internal medicine; Biochemistry; Medicine","score_opus":0.008005343060639367,"score_gpt":0.21657973853777482,"score_spread":0.20857439547713547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2557428787","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9607618,0.00088473386,0.037694577,0.00020738597,0.00014344003,0.00017953831,0.000027916494,0.0000079076035,0.00009270835],"genre_scores_gemma":[0.99904186,0.0003565343,0.00027897954,0.000028777127,0.00010488039,0.000017406104,0.00002343622,0.00001435913,0.0001337796],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988879,0.000105660736,0.0003880404,0.00026733874,0.000112664806,0.00023840253],"domain_scores_gemma":[0.999501,0.000026045931,0.00015186779,0.00020663728,0.00007488984,0.000039583312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013065097,0.000121357305,0.00024504133,0.00010820007,0.000019533692,0.0000016762506,0.00011240108,0.00013444947,0.00020113995],"category_scores_gemma":[0.00003926529,0.000098233875,0.00009189206,0.00005883423,0.00008296481,0.0000069336043,0.00002093083,0.00006101255,0.0000033113624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065273937,0.00008688731,0.0009830468,0.000010195633,0.00004029402,0.0000046775963,0.000029886956,0.00016007264,0.9891005,0.00044530147,0.00005337675,0.008432991],"study_design_scores_gemma":[0.0027411967,0.0007628448,0.00367943,0.000020140875,0.00001927489,0.000018544148,0.000037214853,0.00007166424,0.9916307,0.0005301232,0.00037864945,0.00011027098],"about_ca_topic_score_codex":0.000055654164,"about_ca_topic_score_gemma":0.000023704719,"teacher_disagreement_score":0.038280055,"about_ca_system_score_codex":0.000016430353,"about_ca_system_score_gemma":0.00004416939,"threshold_uncertainty_score":0.40058613},"labels":[],"label_agreement":null},{"id":"W2560120632","doi":"10.1371/journal.pone.0167718","title":"Structural Mapping and Functional Characterization of Zebrafish Class B G-Protein Coupled Receptor (GPCR) with Dual Ligand Selectivity towards GLP-1 and Glucagon","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"National Science Foundation","keywords":"G protein-coupled receptor; Glucagon receptor; Zebrafish; Receptor; Glucagon-like peptide 1 receptor; Biology; Ligand (biochemistry); Cell biology; G protein; Glucagon; Biochemistry; Chemistry; Agonist; Gene","score_opus":0.018292744813962862,"score_gpt":0.18377345591213504,"score_spread":0.16548071109817217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560120632","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973804,0.000063319654,0.0020754293,0.00017362024,0.00002780064,0.00021284173,0.00003855672,0.000010555527,0.000017492688],"genre_scores_gemma":[0.99846584,0.00007022615,0.0009463319,0.000030252506,0.00017671257,0.000017032651,0.000077072466,0.000016472213,0.00020004639],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925333,0.00003260055,0.00013959552,0.0002715776,0.0001638419,0.00013903814],"domain_scores_gemma":[0.9995989,0.000007625713,0.000106410174,0.00009758528,0.00012886674,0.00006057043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000110544286,0.00012297586,0.00017392325,0.000031520598,0.00006808086,0.000020518544,0.00002952041,0.00010626405,0.000052158513],"category_scores_gemma":[0.000039285624,0.000087870256,0.000017922608,0.00005344406,0.00006428876,0.000014649887,0.000044759516,0.000047782472,5.635935e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024081607,0.000047899764,0.0017040622,0.00005251431,0.000119708646,2.8915818e-7,0.00003631591,2.1787605e-7,0.9965691,0.00006617362,0.0000030246392,0.001159908],"study_design_scores_gemma":[0.00077962264,0.000420225,0.015109007,0.0001248955,0.000024136849,0.0000041575904,0.000017307462,0.00013450223,0.9831504,0.00003621206,0.00005829671,0.0001411882],"about_ca_topic_score_codex":0.000009538655,"about_ca_topic_score_gemma":0.000007511104,"teacher_disagreement_score":0.01341862,"about_ca_system_score_codex":0.000010906389,"about_ca_system_score_gemma":0.00004364838,"threshold_uncertainty_score":0.3583245},"labels":[],"label_agreement":null},{"id":"W2560585019","doi":"10.1016/j.coph.2016.11.008","title":"Analyzing biased responses of GPCR ligands","year":2016,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Functional selectivity; Effector; Biology; Signaling proteins; Receptor; Computational biology; Categorization; Signal transduction; Cell signaling; Diversity (politics); Neuroscience; Cell biology; Computer science; Genetics; Artificial intelligence","score_opus":0.10233968669455046,"score_gpt":0.43933024678215626,"score_spread":0.3369905600876058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2560585019","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002873011,0.99040747,0.00047745486,0.000014728665,0.008267989,0.00039595886,0.000114420654,0.000008683237,0.000026017015],"genre_scores_gemma":[0.000240588,0.99786973,0.000043824297,0.000006791908,0.0013282005,0.00011765493,0.0002766623,0.000041493913,0.00007503539],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99793357,0.00034588188,0.0007761758,0.00051538507,0.00010337202,0.00032562463],"domain_scores_gemma":[0.9990002,0.00012383037,0.00047455565,0.0002454816,0.00007067884,0.000085273496],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004942026,0.0003341934,0.00096638623,0.00035858853,0.000034126908,0.0000075996895,0.0003682814,0.00037094392,0.00041837717],"category_scores_gemma":[0.00007981608,0.00026088924,0.00040041885,0.00022355784,0.000080459744,0.000003219823,0.0001786852,0.00024503056,0.000019092597],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010660233,0.00013846342,0.000025530906,0.0072644195,0.0001751954,0.0000012714789,0.000013107015,0.0000019678891,0.039206825,0.00006594605,0.008544942,0.94445574],"study_design_scores_gemma":[0.0005551605,0.00014867492,0.0000010557848,0.0053558354,0.00008878393,0.00000830999,0.0000026056364,0.0000031042648,0.017079493,0.000018245042,0.97646326,0.0002754522],"about_ca_topic_score_codex":0.0000013799312,"about_ca_topic_score_gemma":1.9268099e-7,"teacher_disagreement_score":0.96791834,"about_ca_system_score_codex":0.000038482158,"about_ca_system_score_gemma":0.00034453245,"threshold_uncertainty_score":0.9999843},"labels":[],"label_agreement":null},{"id":"W2563225553","doi":"10.1016/j.autneu.2015.07.078","title":"Cardiovascular autonomic regulation in mice overexpressing the vesicular acetylcholine transporter (VAChT) gene","year":2015,"lang":"en","type":"article","venue":"Autonomic Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Acetylcholine; Vesicular acetylcholine transporter; Internal medicine; Endocrinology; Biology; Neuroscience; Medicine; Choline acetyltransferase","score_opus":0.023026468685797403,"score_gpt":0.23431202392822567,"score_spread":0.21128555524242826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2563225553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98563594,0.00073140033,0.012411378,0.00013847921,0.00065717223,0.00022459478,0.0000054139364,0.000017895058,0.00017770584],"genre_scores_gemma":[0.99841446,0.000051105322,0.00059393444,0.00048661063,0.00017405745,0.00001853177,0.000016303977,0.000023017465,0.00022198787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853325,0.00010996852,0.00028664854,0.0005734842,0.00018771685,0.00030890483],"domain_scores_gemma":[0.99926853,0.000007750045,0.00008771398,0.0005101281,0.000031897798,0.00009395894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00076850096,0.00016992424,0.00018047848,0.000048664373,0.00011958633,0.00007364202,0.00041661286,0.000091016576,0.000006868344],"category_scores_gemma":[0.000045506793,0.00014028038,0.00015925313,0.00013367063,0.00011051954,0.000025193114,0.00008199202,0.00012265026,0.000007281272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015898213,0.00001588637,0.00017257655,0.0000016439943,0.0000063666516,0.0000033969886,0.00009899365,0.059494104,0.9390939,0.000047709465,0.00008086001,0.00096867705],"study_design_scores_gemma":[0.00066691265,0.000071171315,0.0060306564,0.000012291469,0.000021383816,0.00003413497,0.000046411198,0.016654683,0.94510424,0.000117847536,0.030992586,0.00024765584],"about_ca_topic_score_codex":0.00006289725,"about_ca_topic_score_gemma":0.00000625443,"teacher_disagreement_score":0.042839423,"about_ca_system_score_codex":0.000059006645,"about_ca_system_score_gemma":0.00019070283,"threshold_uncertainty_score":0.57204676},"labels":[],"label_agreement":null},{"id":"W2565357631","doi":"10.7554/elife.17517","title":"eIF2α-mediated translational control regulates the persistence of cocaine-induced LTP in midbrain dopamine neurons","year":2016,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; Howard Hughes Medical Institute; National Institute on Drug Abuse; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Long-term potentiation; Ventral tegmental area; Dopamine; Neuroscience; Excitatory postsynaptic potential; Neurotransmission; Biology; Dopaminergic; Inhibitory postsynaptic potential; Biochemistry","score_opus":0.013982499144452465,"score_gpt":0.22160934020587633,"score_spread":0.20762684106142387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2565357631","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960097,0.00030508198,0.0011447183,0.0021785751,0.00008003439,0.00014076167,0.0000345506,0.0000052827136,0.00010129332],"genre_scores_gemma":[0.9992716,0.000044268465,0.000101707075,0.0002853203,0.000098022174,0.000011119497,0.00001958791,0.000010612554,0.00015780103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992338,0.000083142804,0.0002062287,0.00018112478,0.00014448677,0.00015125117],"domain_scores_gemma":[0.9995696,0.00009014133,0.00006761356,0.00016865089,0.00006503225,0.00003896658],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026911317,0.00009185967,0.00011763974,0.000027696993,0.000034398618,0.000006097095,0.00014753782,0.00007961592,0.000072166025],"category_scores_gemma":[0.00018625277,0.000054340526,0.000071783514,0.00006788615,0.00005584625,0.0000032793414,0.000015447646,0.000046339963,0.000004193753],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000062552586,0.00002117969,0.0012948301,0.0000030305084,0.000017021988,0.0000010931511,0.000049162125,0.000025955374,0.99754685,0.00015633168,0.00009207449,0.00072994013],"study_design_scores_gemma":[0.0014549079,0.0001836261,0.007809879,0.000029024312,0.000009459046,0.0000050466806,0.000073081224,0.00040943763,0.9871868,0.000044698427,0.0026804102,0.000113626644],"about_ca_topic_score_codex":0.000010942675,"about_ca_topic_score_gemma":0.000023621164,"teacher_disagreement_score":0.010360025,"about_ca_system_score_codex":0.0000045183156,"about_ca_system_score_gemma":0.000050925195,"threshold_uncertainty_score":0.22159424},"labels":[],"label_agreement":null},{"id":"W2565747990","doi":"10.18632/oncotarget.14121","title":"Peptide-guided targeting of GPR55 for anti-cancer therapy","year":2016,"lang":"en","type":"article","venue":"Oncotarget","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Associazione Italiana per la Ricerca sul Cancro; Ministero della Salute","keywords":"Peptide; Biology; Molecular biology; Receptor; Peptide library; Phage display; Cancer research; Biochemistry; Peptide sequence; Gene","score_opus":0.025443125361154912,"score_gpt":0.2980921066163669,"score_spread":0.27264898125521203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2565747990","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97607887,0.0013496706,0.021439651,0.00023510293,0.00026354034,0.00020637202,0.000063604355,0.00001023067,0.00035293636],"genre_scores_gemma":[0.9869981,0.0014857872,0.008040512,0.00021039357,0.0005041843,0.000055986453,0.000043188433,0.0000338835,0.002627959],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919236,0.000025180276,0.00022377864,0.00024740628,0.00009305219,0.00021820485],"domain_scores_gemma":[0.999506,0.00001885874,0.00012229203,0.00017277131,0.00013172464,0.000048329402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023773898,0.00011992219,0.0001712793,0.000022304694,0.000049558155,0.0000068366244,0.00014226702,0.00010184276,0.00035504487],"category_scores_gemma":[0.000058861213,0.000079677855,0.00013983503,0.000034854955,0.00003205802,0.000003828972,0.00003140501,0.000023073731,0.0000041690064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052859672,0.000029125342,0.0040918365,0.000010734867,0.00004344359,1.4904157e-7,0.00001917933,0.000014291368,0.97884864,0.00015961134,0.014438815,0.0022913404],"study_design_scores_gemma":[0.0007681488,0.00017363322,0.00016756007,0.000018807277,0.0000042270285,4.5756434e-7,0.000015537933,0.000014362815,0.84512144,0.0002425613,0.15335347,0.00011978383],"about_ca_topic_score_codex":0.000013239994,"about_ca_topic_score_gemma":0.0000018270705,"teacher_disagreement_score":0.13891464,"about_ca_system_score_codex":0.000009061211,"about_ca_system_score_gemma":0.000054072418,"threshold_uncertainty_score":0.38874924},"labels":[],"label_agreement":null},{"id":"W2566807240","doi":"10.1021/acschemneuro.6b00396","title":"Biological Insights of the Dopaminergic Stabilizer ACR16 at the Binding Pocket of Dopamine D2 Receptor","year":2016,"lang":"en","type":"article","venue":"ACS Chemical Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dopaminergic; Dopamine receptor D2; Dopamine; Dopamine receptor; Pharmacology; Neuroscience; Receptor; Chemistry; Medicine; Psychology; Biochemistry","score_opus":0.017825723609823218,"score_gpt":0.23259490420037007,"score_spread":0.21476918059054687,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2566807240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988084,0.00015763762,0.0001946941,0.0003172356,0.0002802044,0.00013158597,0.000020654665,0.000006024812,0.0000836076],"genre_scores_gemma":[0.9988299,0.00016820607,0.00006580056,0.00023106119,0.00006396782,0.000008600874,0.0000036191236,0.0000100365005,0.00061879924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99874026,0.00008865799,0.00028272366,0.00039766947,0.00025164627,0.00023905278],"domain_scores_gemma":[0.9991229,0.00010115401,0.00017599323,0.00047212665,0.000068502675,0.00005931037],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020633973,0.00013929472,0.00015871567,0.000016445943,0.0000963681,0.000007691699,0.00070056116,0.00011014191,0.000082818544],"category_scores_gemma":[0.00067205465,0.000055977132,0.00011609683,0.00022511976,0.00074348436,0.0000064801584,0.0005895391,0.00007401816,0.0000033273425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000369185,0.000035526304,0.00076712284,0.0000042506144,0.000002269615,1.9766586e-7,0.000013421755,0.0000027424546,0.998191,0.00009263733,0.00022723919,0.00062668056],"study_design_scores_gemma":[0.00021879778,0.00013322399,0.0002287693,0.000019105966,0.0000040486325,0.0000068040727,0.0000151149625,0.0000057654966,0.99022776,0.00005374391,0.008994096,0.00009279624],"about_ca_topic_score_codex":0.0000023302266,"about_ca_topic_score_gemma":8.393418e-7,"teacher_disagreement_score":0.008766856,"about_ca_system_score_codex":0.000013872318,"about_ca_system_score_gemma":0.000033586737,"threshold_uncertainty_score":0.2739399},"labels":[],"label_agreement":null},{"id":"W2566855748","doi":"10.1016/j.phrs.2016.12.036","title":"Pharmacological chaperone approaches for rescuing GPCR mutants: Current state, challenges, and screening strategies","year":2016,"lang":"en","type":"review","venue":"Pharmacological Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Chaperone (clinical); Computational biology; Receptor; Protein folding; Mutant; Translation (biology); Biology; Chemical chaperone; Bioinformatics; Cell biology; Medicine; Genetics; Gene; Messenger RNA","score_opus":0.5250011719032659,"score_gpt":0.5041081803242727,"score_spread":0.02089299157899316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2566855748","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00036656548,0.99276364,0.0033296712,0.000081521066,0.00029574046,0.0024888574,0.00015916032,0.000044122364,0.00047073426],"genre_scores_gemma":[0.0019538384,0.9937622,0.0007090589,0.000020085761,0.0013225292,0.0017755163,0.00014985628,0.000086067186,0.00022086309],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9945421,0.0012575297,0.00070647954,0.0015328578,0.00059810845,0.0013629101],"domain_scores_gemma":[0.9980304,0.0007826318,0.00021768316,0.00025587933,0.00025203012,0.0004613286],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0036089572,0.00063271594,0.0012057758,0.00021554073,0.00042400742,0.00016396,0.000772814,0.00054268085,0.00023433991],"category_scores_gemma":[0.0004002081,0.00039740073,0.00040832534,0.00017901315,0.00044602752,0.000020871277,0.00092905614,0.0011159377,0.00001730826],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019416101,0.0001679984,9.934301e-8,0.002992891,0.00034021772,0.0000145561135,0.000032038584,0.0000022992185,0.010758176,0.0006279128,0.00042421566,0.98444545],"study_design_scores_gemma":[0.00088877336,0.00096286274,0.000001123603,0.0019123633,0.0002050273,0.00002253476,0.00011303882,0.00007717321,0.002174362,0.00092893484,0.992121,0.000592844],"about_ca_topic_score_codex":0.0000011498157,"about_ca_topic_score_gemma":0.0000012554337,"teacher_disagreement_score":0.9916968,"about_ca_system_score_codex":0.0000785901,"about_ca_system_score_gemma":0.0003479537,"threshold_uncertainty_score":0.99984777},"labels":[],"label_agreement":null},{"id":"W2570626931","doi":"10.71781/25793","title":"Étude du mécanisme d'inhibition de la libération de dopamine par les autorécepteurs D2","year":2006,"lang":"fr","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Université de Montréal","keywords":"Chemistry; Humanities; Philosophy","score_opus":0.003191513011123214,"score_gpt":0.16901165412640853,"score_spread":0.1658201411152853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2570626931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96753615,0.010691472,0.013446164,0.00018543884,0.00072534604,0.0003101341,0.00007265265,0.00008845722,0.0069441614],"genre_scores_gemma":[0.98217386,0.0014354032,0.0033154169,0.00008622178,0.00087346864,0.000040760442,0.0021931024,0.0000781146,0.009803658],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99743366,0.00040946642,0.00045508228,0.000715514,0.00042428038,0.0005620096],"domain_scores_gemma":[0.99861354,0.00006321792,0.00044041983,0.00030134834,0.00028187042,0.00029959306],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.000406367,0.00053246255,0.00035809778,0.00017724419,0.0045902287,0.00012357808,0.00027462924,0.0011916383,0.00007849195],"category_scores_gemma":[0.00007722691,0.0006627933,0.00040202274,0.00016911111,0.0002809095,0.000048111724,0.000107813736,0.00042815052,0.000017837696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043434234,0.0002712514,0.008813727,0.00014225084,0.00021242452,0.0008095946,0.003526216,0.011096189,0.9605832,0.010664876,0.00071656634,0.0027293793],"study_design_scores_gemma":[0.0013322976,0.0003378659,0.031467605,0.0002880565,0.00040847788,0.0011584186,0.0063084643,0.0035257994,0.9200569,0.00045492352,0.033811625,0.0008496071],"about_ca_topic_score_codex":0.022547882,"about_ca_topic_score_gemma":0.0056974757,"teacher_disagreement_score":0.040526323,"about_ca_system_score_codex":0.0026116485,"about_ca_system_score_gemma":0.0016982817,"threshold_uncertainty_score":0.99958235},"labels":[],"label_agreement":null},{"id":"W2577128846","doi":"10.71781/30821","title":"Dépression post-infarctus du myocarde : caractérisations comportementale et biochimique d'un modèle expérimental chez le rat","year":2006,"lang":"fr","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Physics","score_opus":0.004805830112527509,"score_gpt":0.17735916788725992,"score_spread":0.17255333777473242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2577128846","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96612257,0.017064909,0.0030011728,0.00041957234,0.0015763271,0.0006023259,0.00026544303,0.000050896728,0.010896783],"genre_scores_gemma":[0.97228366,0.00090578815,0.0017453649,0.00025169554,0.0003549044,0.00005179008,0.011683173,0.00006467001,0.012658951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972163,0.00031624507,0.0005688356,0.0008833849,0.0005101196,0.00050511316],"domain_scores_gemma":[0.99835604,0.00003208942,0.00053877593,0.00042909817,0.00033087068,0.00031312328],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0002680976,0.00061594695,0.00043756224,0.00018504309,0.0054319766,0.0000928554,0.00040540585,0.000754133,0.00015492317],"category_scores_gemma":[0.000024544657,0.00073348137,0.000525446,0.00014547232,0.00020819982,0.00006689763,0.00026607222,0.00039800678,0.000024478555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048758095,0.000525046,0.0030008971,0.00007867323,0.0003784352,0.00032450157,0.0053191776,0.006963178,0.97698456,0.004148704,0.000959667,0.00082956615],"study_design_scores_gemma":[0.001629809,0.00026479136,0.0070867185,0.00017798516,0.00025135974,0.00043127814,0.01858617,0.0013905844,0.95188636,0.00007507058,0.017458856,0.0007610388],"about_ca_topic_score_codex":0.039423153,"about_ca_topic_score_gemma":0.0040092575,"teacher_disagreement_score":0.035413895,"about_ca_system_score_codex":0.0015026279,"about_ca_system_score_gemma":0.0018930702,"threshold_uncertainty_score":0.9995116},"labels":[],"label_agreement":null},{"id":"W2578755479","doi":"10.18433/j3w31f","title":"Beta Adrenoceptor Polymorphism and Clinical Response to Sertraline in Major Depressive Patients","year":2017,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Sertraline; Allele; Depression (economics); Internal medicine; Genotype; Polymorphism (computer science); Medicine; Psychology; Pharmacology; Endocrinology; Gene; Genetics; Biology; Antidepressant","score_opus":0.05905300807824563,"score_gpt":0.4209129766510939,"score_spread":0.36185996857284825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2578755479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953082,0.00085432647,0.00016436915,0.002755837,0.0006869997,0.0001504321,0.00000947353,0.00000219219,0.00006817853],"genre_scores_gemma":[0.99665636,0.00051820365,0.0014246437,0.0008988149,0.00043196,0.0000022039385,9.313831e-7,0.000009589436,0.00005727917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981622,0.00025614304,0.00058028486,0.00031285925,0.00036042448,0.0003281076],"domain_scores_gemma":[0.9988258,0.000086285254,0.00033921484,0.00014830705,0.0001431228,0.00045730412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0022488327,0.00014900093,0.00024854962,0.000099322315,0.00029578185,0.00014374277,0.0006638497,0.00005473531,0.00020477372],"category_scores_gemma":[0.00062241993,0.000113235736,0.00012272745,0.000076912984,0.0003151347,0.000046068748,0.00026571707,0.00024779566,0.000004813989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0026657174,0.0002393673,0.25141364,0.0000071235745,0.00004466531,0.000035311776,0.00004880009,0.000019723073,0.7102418,0.000015754991,0.0005546935,0.03471341],"study_design_scores_gemma":[0.0073967576,0.0013716859,0.09431206,0.00007163688,0.00008097374,0.000055661778,0.00004890982,0.0004607968,0.8340929,0.000063503176,0.06173287,0.000312238],"about_ca_topic_score_codex":0.000019761046,"about_ca_topic_score_gemma":0.0000074694426,"teacher_disagreement_score":0.1571016,"about_ca_system_score_codex":0.000016056429,"about_ca_system_score_gemma":0.00014599957,"threshold_uncertainty_score":0.46176192},"labels":[],"label_agreement":null},{"id":"W2579122244","doi":"10.1074/jbc.m116.750380","title":"Differential Contribution of Transmembrane Domains IV, V, VI, and VII to Human Angiotensin II Type 1 Receptor Homomer Formation","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Transmembrane domain; Angiotensin II; Receptor; G protein-coupled receptor; Transmembrane protein; Biophysics; Chemistry; Biology; Signal transduction; Cell biology; Biochemistry","score_opus":0.01701334320011413,"score_gpt":0.26158738132849174,"score_spread":0.2445740381283776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2579122244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99698466,0.00020699258,0.0023207425,0.00019703836,0.000112498565,0.00006506079,0.000015899257,0.000002525026,0.000094606454],"genre_scores_gemma":[0.99880993,0.00019254407,0.00048408037,0.00003486358,0.00036077533,9.689724e-7,0.000047422287,0.0000058058035,0.00006360587],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992495,0.000023973253,0.00033976286,0.00013357554,0.00011002264,0.00014312814],"domain_scores_gemma":[0.9991145,0.00000759267,0.00036918093,0.00015827143,0.00023879182,0.00011166544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018859736,0.00011551778,0.00025109283,0.000016457316,0.00020798975,0.000028074275,0.00018661536,0.0002397603,0.00017108346],"category_scores_gemma":[0.00013381714,0.00008295824,0.00012366935,0.000022185091,0.00008302813,0.000009723313,0.000078379206,0.000112583584,6.004016e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000289645,0.0000541488,0.0002304195,0.000013334739,0.000038166243,0.000001810629,0.000024590869,0.0000022777442,0.998359,0.000019976607,0.00022235069,0.0007442842],"study_design_scores_gemma":[0.00073118304,0.00079131336,0.0012630004,0.00004218024,0.000021079855,0.000038037073,0.00003432088,0.0000073977567,0.9942723,0.00008989565,0.0026015393,0.00010775078],"about_ca_topic_score_codex":0.0000020000855,"about_ca_topic_score_gemma":8.052422e-7,"teacher_disagreement_score":0.0040866933,"about_ca_system_score_codex":0.000012353627,"about_ca_system_score_gemma":0.000016698263,"threshold_uncertainty_score":0.33829388},"labels":[],"label_agreement":null},{"id":"W2579331173","doi":"10.1007/978-3-319-41523-9_18","title":"Erratum to: 7TM Domain Structure of Adhesion GPCRs","year":2016,"lang":"en","type":"erratum","venue":"Handbook of experimental pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"G protein-coupled receptor; Domain (mathematical analysis); Biology; Receptor; Genetics; Mathematics","score_opus":0.00911731432771299,"score_gpt":0.2898164944768881,"score_spread":0.2806991801491751,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2579331173","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6975176,0.1503777,0.0028862034,0.00027997835,0.119426034,0.0036335404,0.0020182987,0.0000746524,0.023785995],"genre_scores_gemma":[0.89802814,0.0047785044,0.006640571,0.001702779,0.009093023,0.00015982463,0.0017417247,0.0003613834,0.07749403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99798435,0.00013980502,0.0005691166,0.0006289562,0.0002673805,0.00041038758],"domain_scores_gemma":[0.99891174,0.000014385763,0.0004237786,0.00034392904,0.0001231461,0.00018301314],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000100334895,0.00043748342,0.00066767016,0.00014905345,0.000065109874,0.0000071230825,0.00048372537,0.0008216171,0.0029616228],"category_scores_gemma":[0.00001196701,0.00036800603,0.00027673278,0.00006989292,0.00017548521,0.0000048043767,0.00036190724,0.0002619471,0.000012106664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030399178,0.00006687615,0.000001896036,0.00004221907,0.00012256864,0.0000034954219,0.00009075733,0.0000018332387,0.568711,0.000015446636,0.43052042,0.000119504504],"study_design_scores_gemma":[0.00094977766,0.0011921002,0.0000010750235,0.00021827627,0.000040842406,0.000009335624,0.00008695148,0.0000013005704,0.78162473,0.00008545726,0.21549462,0.00029550737],"about_ca_topic_score_codex":0.000013076082,"about_ca_topic_score_gemma":0.000003797598,"teacher_disagreement_score":0.2150258,"about_ca_system_score_codex":0.000050063296,"about_ca_system_score_gemma":0.00022049624,"threshold_uncertainty_score":0.9998772},"labels":[],"label_agreement":null},{"id":"W2581290476","doi":"10.1007/978-1-4939-6625-7_14","title":"Intracellular Free Calcium Measurement Using Confocal Imaging","year":2017,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Confocal; Confocal microscopy; Intracellular; Microscopy; Fluorescence; Calcium in biology; Biophysics; Materials science; Fluorescence microscope; Nanotechnology; Biological system; Biomedical engineering; Computer science; Chemistry; Optics; Biology; Cell biology; Biochemistry; Physics; Engineering","score_opus":0.06386367672798125,"score_gpt":0.4027732318002565,"score_spread":0.3389095550722752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2581290476","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.063616544,0.0024172596,0.9322218,0.00016008221,0.00065727474,0.00019956219,0.0000059059366,0.000011137772,0.0007104472],"genre_scores_gemma":[0.30874327,0.000031282187,0.69065505,0.0002787188,0.00018556906,0.0000204052,0.000015247654,0.000040347324,0.000030085823],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977098,0.0006879319,0.00036448747,0.00060709077,0.00014379028,0.00048689757],"domain_scores_gemma":[0.99831843,0.000014955019,0.00020908068,0.0012252566,0.00013314998,0.00009910736],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0025092135,0.00025249773,0.00031862364,0.00008842929,0.00022463402,0.00007070992,0.0008145985,0.00027258915,0.000057123212],"category_scores_gemma":[0.0011523961,0.00024888685,0.00015293113,0.00004220619,0.00021924537,0.0000053630865,0.00054754457,0.00021514721,0.0000025481993],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003069536,0.000028481893,0.001141955,0.000008697456,0.000044728025,0.00002971605,0.00001584665,0.000070656075,0.9842118,0.0016099305,0.000022078091,0.012785406],"study_design_scores_gemma":[0.0007117731,0.00008353083,0.00010830784,0.00002226143,0.000026319258,0.000026342463,0.0000349345,0.0022439812,0.9855186,0.0051146555,0.005808356,0.00030094752],"about_ca_topic_score_codex":0.00018632575,"about_ca_topic_score_gemma":0.00001932371,"teacher_disagreement_score":0.24512672,"about_ca_system_score_codex":0.000046376274,"about_ca_system_score_gemma":0.0000992052,"threshold_uncertainty_score":0.99999636},"labels":[],"label_agreement":null},{"id":"W2583270084","doi":"10.1016/j.bpj.2016.11.515","title":"The M2 Muscarinic Receptor Signaling Complex Resolved by Single Molecule Tracking in Live Cells","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Receptor; G protein-coupled receptor; Chinese hamster ovary cell; Internalization; Cell biology; Total internal reflection fluorescence microscope; Fluorescence recovery after photobleaching; Biophysics; Muscarinic acetylcholine receptor; Biology; Membrane protein; Green fluorescent protein; Chemistry; Biochemistry; Membrane; Gene","score_opus":0.025703873176702387,"score_gpt":0.2700866847911357,"score_spread":0.2443828116144333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2583270084","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962494,0.00020050896,0.0023674562,0.00030464327,0.00044405166,0.0001147063,0.000011356822,0.0000068951554,0.00030102074],"genre_scores_gemma":[0.99790925,0.0001681361,0.000684275,0.00011427635,0.0008644633,0.0000052793403,0.000015674077,0.00003055982,0.00020809524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985949,0.00012427008,0.00033382492,0.00029306396,0.00023620923,0.00041773927],"domain_scores_gemma":[0.999036,0.000039207254,0.00030049297,0.0003797465,0.00009739097,0.00014712385],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003846462,0.00018760235,0.00019681889,0.000022191865,0.0009065341,0.000516567,0.00064785767,0.00013472495,0.00007644762],"category_scores_gemma":[0.00010698432,0.00014080259,0.00020186928,0.000035369354,0.00013796984,0.0000148085055,0.0001535171,0.00033153011,0.000024897736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008082126,0.000099001634,0.000043225256,0.0000029597738,0.000031613854,0.000007683409,0.000058603233,0.000031050244,0.9936332,0.000034486024,0.0017231726,0.0042541604],"study_design_scores_gemma":[0.0005210875,0.00030051393,0.00014875963,0.00003696041,0.00001031271,0.000009111778,0.00017798523,0.00025946682,0.9867138,0.00008758583,0.011531008,0.00020339421],"about_ca_topic_score_codex":0.000025347494,"about_ca_topic_score_gemma":0.0000111512,"teacher_disagreement_score":0.009807835,"about_ca_system_score_codex":0.000035489596,"about_ca_system_score_gemma":0.00004428998,"threshold_uncertainty_score":0.6972419},"labels":[],"label_agreement":null},{"id":"W2583377287","doi":"10.1016/j.bpj.2016.11.1772","title":"The Role of G-Protein-Coupled Receptor Activation by Conformational Selection as Revealed by Single-Molecule Fluorescence","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Förster resonance energy transfer; G protein-coupled receptor; Chemistry; Agonist; Single-molecule FRET; Biophysics; Inverse agonist; Ligand (biochemistry); Receptor; Adenosine receptor; Stereochemistry; Fluorescence; Biochemistry; Biology","score_opus":0.005886672018355273,"score_gpt":0.22777830014463127,"score_spread":0.221891628126276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2583377287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99550056,0.00006901797,0.0036305238,0.0002607892,0.00010451,0.0001234883,0.000011399621,0.0000045475967,0.00029517553],"genre_scores_gemma":[0.99878573,0.000059404305,0.00039685532,0.00003148103,0.00034198866,0.000008021713,0.000043469394,0.000012000922,0.0003210647],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913263,0.000049313716,0.00024057968,0.00013759093,0.00025870145,0.00018117407],"domain_scores_gemma":[0.99909025,0.000012177773,0.0004342661,0.0001721491,0.00020908008,0.00008205781],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001911346,0.00011226821,0.000109155,0.000012581843,0.0006927174,0.00017506175,0.00029915676,0.00010141653,0.00004915667],"category_scores_gemma":[0.00016532314,0.00008320001,0.00009929526,0.00002980375,0.00009362054,0.000025576304,0.00004831498,0.00015065137,0.000009245659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014567531,0.000059360438,0.000028484359,0.0000025476818,0.00003221578,6.419188e-8,0.000012041261,0.0000023278035,0.993589,0.00034275503,0.0014044672,0.0043810965],"study_design_scores_gemma":[0.00031608337,0.0003597125,0.00004412408,0.000022274366,0.0000062715094,0.0000057789102,0.000045754514,0.00055994745,0.98892856,0.0002702139,0.009337812,0.0001034937],"about_ca_topic_score_codex":0.000020501946,"about_ca_topic_score_gemma":5.1062256e-7,"teacher_disagreement_score":0.007933345,"about_ca_system_score_codex":0.0000237672,"about_ca_system_score_gemma":0.00006189525,"threshold_uncertainty_score":0.53278923},"labels":[],"label_agreement":null},{"id":"W2583750065","doi":"10.1016/j.bpj.2016.11.329","title":"Protein Folding upon Binding Revealed by Molecular Dynamics Simulation","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Interactome; Folding (DSP implementation); Macromolecule; Molecular dynamics; Proteome; Computational biology; Function (biology); Biophysics; Protein folding; Cell biology; Biology; Chemistry; Bioinformatics; Biochemistry; Computational chemistry","score_opus":0.01033671624106719,"score_gpt":0.2689663950178619,"score_spread":0.2586296787767947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2583750065","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9309482,0.000034664943,0.0683961,0.0001404294,0.00017741202,0.000115589595,0.000010402221,0.000007297931,0.00016991668],"genre_scores_gemma":[0.99779534,0.000012686971,0.0012660956,0.000034929744,0.00049684587,0.0000046639775,0.000033860946,0.000026867112,0.0003287207],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999069,0.00005100855,0.00019922413,0.00022741388,0.00020157648,0.00025179822],"domain_scores_gemma":[0.9992376,0.000005479351,0.00026464654,0.00028189493,0.00007872251,0.00013166918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020303212,0.00014576326,0.00014387426,0.000026701027,0.0005366926,0.00027005438,0.0003066081,0.00013286543,0.00002518671],"category_scores_gemma":[0.00011545174,0.00013199686,0.00015427083,0.000025026548,0.000031664127,0.000015605168,0.00009683836,0.00017987673,0.000010760574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039322298,0.00003395091,0.00007242908,0.000005578361,0.000032455475,0.000011022622,0.0000071362947,0.000445421,0.99568224,0.00033197005,0.00005325054,0.0032852204],"study_design_scores_gemma":[0.00044569702,0.00023961485,0.000052287287,0.000047905436,0.000016737813,0.000013434824,0.000017395792,0.01870158,0.97913784,0.00026784046,0.00084967504,0.00021001803],"about_ca_topic_score_codex":0.000004548755,"about_ca_topic_score_gemma":8.6159537e-7,"teacher_disagreement_score":0.06713001,"about_ca_system_score_codex":0.000049592607,"about_ca_system_score_gemma":0.00004069213,"threshold_uncertainty_score":0.5382676},"labels":[],"label_agreement":null},{"id":"W2584155195","doi":"10.1124/mol.116.108035","title":"β-Arrestin-Mediated Regulation of the Human Ether-a-go-go-Related Gene Potassium Channel","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"hERG; HEK 293 cells; G protein-coupled receptor; Arrestin; Cell biology; Chemistry; Potassium channel; Signal transduction; Pharmacology; Receptor; Biology; Biochemistry; Endocrinology","score_opus":0.01330078029083944,"score_gpt":0.281600554282787,"score_spread":0.2682997739919476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2584155195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99457496,0.00038794355,0.0015623538,0.0006525021,0.0011542221,0.00036031374,0.000020208232,0.00001738999,0.0012700781],"genre_scores_gemma":[0.9981685,0.000026003818,0.00020935027,0.00040321477,0.00018626163,0.000031310297,0.000102761274,0.00004255739,0.00083001266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985491,0.00022874573,0.00033482097,0.00038936455,0.00018005217,0.00031793324],"domain_scores_gemma":[0.9986744,0.000011203591,0.00044274647,0.00064786756,0.0001379775,0.00008579306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032682504,0.00020773849,0.00022222036,0.000044898457,0.00040397543,0.00002559195,0.0006652395,0.00031157237,0.0003576615],"category_scores_gemma":[0.00007246948,0.0001737053,0.00018603411,0.000063981206,0.00023511503,0.0000059848912,0.00031244406,0.00019363771,0.000018737805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003274732,0.00006160615,0.00025349503,0.000011618523,0.0001620175,0.00000857929,0.00003967458,0.0006267084,0.9973433,0.00021877904,0.001036167,0.00020529727],"study_design_scores_gemma":[0.0011614931,0.00012953355,0.0032554753,0.000011214028,0.00009631529,0.000014367286,0.0000075680427,0.00062384264,0.99097395,0.00070676033,0.0028290348,0.00019042134],"about_ca_topic_score_codex":0.000031892287,"about_ca_topic_score_gemma":0.0000062527974,"teacher_disagreement_score":0.0063693356,"about_ca_system_score_codex":0.00001764686,"about_ca_system_score_gemma":0.00006884919,"threshold_uncertainty_score":0.70834965},"labels":[],"label_agreement":null},{"id":"W2584522550","doi":"10.1016/j.bpj.2016.11.1882","title":"Interdomain Conformational Changes in Visual Arrestin upon Binding to Different Forms of Rhodopsin","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Rhodopsin; Arrestin; Opsin; Chemistry; Biophysics; Crystallography; Stereochemistry; G protein-coupled receptor; Biology; Biochemistry; Receptor; Retinal","score_opus":0.016587175015570478,"score_gpt":0.293609900198688,"score_spread":0.2770227251831175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2584522550","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958421,0.0000062936447,0.0034906885,0.00023063582,0.00023672196,0.00007548856,0.000009019912,0.000001911107,0.00010711571],"genre_scores_gemma":[0.9990641,0.000015566913,0.00040548746,0.000050229508,0.00040159342,0.000004525013,0.000013379826,0.000009154931,0.00003598209],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992754,0.000027597069,0.00021613574,0.000121233476,0.00016640671,0.00019326228],"domain_scores_gemma":[0.9995072,0.000009793629,0.00019421564,0.00013009727,0.000047911642,0.00011082125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001862056,0.000109033856,0.00016545589,0.00006836647,0.00013377993,0.00007999931,0.00024502855,0.00006909052,0.000042272408],"category_scores_gemma":[0.00008497789,0.00008248008,0.000080335405,0.00002399753,0.000030888583,0.000009891376,0.0001330552,0.00011668506,0.000006214303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011171494,0.00006254725,0.000717916,0.0000074825434,0.0000147895435,0.0000032595665,0.000058307887,0.00002281688,0.9940619,0.00040174057,0.000041881427,0.0044956338],"study_design_scores_gemma":[0.0004904281,0.0004785046,0.006920416,0.0000823196,0.000004424834,0.000016236721,0.000096962,0.00041161393,0.9909273,0.00016175542,0.0002921169,0.00011795427],"about_ca_topic_score_codex":0.0000046997893,"about_ca_topic_score_gemma":0.000024660336,"teacher_disagreement_score":0.0062025,"about_ca_system_score_codex":0.000020350599,"about_ca_system_score_gemma":0.000023576074,"threshold_uncertainty_score":0.336344},"labels":[],"label_agreement":null},{"id":"W2584660469","doi":"10.1016/j.bpj.2016.11.2702","title":"Comparing and Contrasting Fluorotryptophan Substitutions for 19 F Membrane Protein NMR Spectroscopy","year":2017,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chemistry; Heteronuclear molecule; Nuclear magnetic resonance spectroscopy; Fluorine-19 NMR; Transmembrane protein; Transmembrane domain; G protein-coupled receptor; Membrane protein; Chemical shift; Amino acid; Stereochemistry; Micelle; Membrane; Crystallography; Receptor; Biochemistry; Organic chemistry; Aqueous solution","score_opus":0.025200447448970452,"score_gpt":0.28231461275751923,"score_spread":0.2571141653085488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2584660469","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9517597,0.00005616804,0.047450233,0.00016982241,0.00014409183,0.00020997587,0.000007896114,0.000006609013,0.00019550858],"genre_scores_gemma":[0.9910938,0.000022342516,0.0077664745,0.000035798123,0.0009696082,0.000018014438,0.00000801154,0.000013531382,0.00007240195],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928415,0.000020603056,0.00016058543,0.00019673326,0.00009692155,0.00024102497],"domain_scores_gemma":[0.99942714,0.000009403288,0.00015691789,0.00017605792,0.00006487072,0.00016562334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016149013,0.00012442075,0.0001784056,0.000017568716,0.00095946266,0.0002581985,0.00019001722,0.00007018588,0.000012086008],"category_scores_gemma":[0.00014346524,0.0001042998,0.00010784497,0.0000113238475,0.00010060736,0.000011765123,0.000063775886,0.00012357789,0.000001756513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070498085,0.00003681687,0.00035159494,0.000011744757,0.000041683947,0.000003023852,0.00000967818,0.00001044149,0.9968016,0.0022520248,0.00003683845,0.00037402942],"study_design_scores_gemma":[0.000938523,0.00021685788,0.0013782268,0.00003579712,0.000019809675,0.000034792938,0.000019437148,0.00089603034,0.99501985,0.0004666076,0.0008289405,0.00014509761],"about_ca_topic_score_codex":0.000010208967,"about_ca_topic_score_gemma":0.000004022027,"teacher_disagreement_score":0.03968376,"about_ca_system_score_codex":0.0000115600205,"about_ca_system_score_gemma":0.00004490191,"threshold_uncertainty_score":0.7379508},"labels":[],"label_agreement":null},{"id":"W2584724062","doi":"10.1016/j.hrthm.2006.02.928","title":"P6-27","year":2006,"lang":"en","type":"article","venue":"Heart Rhythm","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Medicine; Lidocaine; Cardiology; Anesthesia; Pharmacology; Internal medicine","score_opus":0.0066523743720720155,"score_gpt":0.22483750518058257,"score_spread":0.21818513080851054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2584724062","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98865914,0.0009241643,0.004146494,0.00025275728,0.00040571325,0.00008679687,0.000004469757,0.000023081528,0.0054973955],"genre_scores_gemma":[0.9905758,0.000020768965,0.0024167327,0.00035173915,0.00083128264,0.0000061251067,0.000048240054,0.000015850797,0.005733471],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994702,0.000016897857,0.00009924679,0.00017507588,0.00007185747,0.00016676128],"domain_scores_gemma":[0.99975634,0.0000026936034,0.000018111841,0.00016220247,0.000026271473,0.000034369692],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007682398,0.000075313976,0.00007174566,0.000014271775,0.000050351264,0.000016264059,0.00003447514,0.00007767896,0.00024563534],"category_scores_gemma":[0.0000068549493,0.00007092247,0.00006201947,0.000034132394,0.000015743966,0.0000012766567,0.000027770695,0.000039014878,0.00011103639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008444105,0.000018703517,0.00025922846,0.0000040351665,0.0000049575583,0.0000043300993,0.0000038914577,0.00005867691,0.9640587,0.0010690772,0.034097884,0.00041205526],"study_design_scores_gemma":[0.00011236338,0.000053091404,0.00023861304,0.0000033479084,0.0000020489408,0.00010926192,0.000006349749,0.00002532551,0.54942334,0.00036222272,0.4495769,0.000087127824],"about_ca_topic_score_codex":0.00003845328,"about_ca_topic_score_gemma":0.00001325114,"teacher_disagreement_score":0.41547903,"about_ca_system_score_codex":0.000004062796,"about_ca_system_score_gemma":0.00001871782,"threshold_uncertainty_score":0.28921342},"labels":[],"label_agreement":null},{"id":"W2586772926","doi":"10.1002/chem.201605575","title":"Propagation of the Allosteric Modulation Induced by Sodium in the δ‐Opioid Receptor","year":2017,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Burroughs Wellcome Fund","keywords":"Allosteric regulation; G protein-coupled receptor; Chemistry; Allosteric modulator; Biophysics; Receptor; Sodium channel; Intracellular; Ion channel; Allosteric enzyme; Helix (gastropod); Sodium; Cell biology; Biochemistry; Biology; Ecology","score_opus":0.01607413115570745,"score_gpt":0.23159608560115327,"score_spread":0.21552195444544583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586772926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99744225,0.000077997356,0.0005157934,0.00026086523,0.00016404408,0.00008655292,0.000004427536,0.0000018535346,0.0014462438],"genre_scores_gemma":[0.99908745,0.000040630028,0.000090297355,0.00006931303,0.0003677485,0.0000021402936,0.00001787117,0.000015728758,0.00030880517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991474,0.00016630851,0.0002454685,0.00014315991,0.0001664913,0.00013117705],"domain_scores_gemma":[0.9990831,0.000004217652,0.00039506351,0.00041604994,0.00006686806,0.000034719604],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007211,0.00010084631,0.00007832762,0.0000067691294,0.00028732035,0.00011394529,0.00065960595,0.00004672333,0.000053860775],"category_scores_gemma":[0.00014925825,0.00006217733,0.000080718935,0.000028852357,0.00005223151,0.000009175196,0.00010205197,0.0002154484,0.0000027196872],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022194861,0.00002476273,0.00026654694,0.0000114593095,0.0000085824595,0.0000012310451,0.00012901454,0.000010970006,0.9954587,0.0000017756307,0.00077895797,0.003285776],"study_design_scores_gemma":[0.00044004878,0.000055851877,0.0031408686,0.000047681737,0.0000070665496,0.00003852689,0.00013770534,0.00022460466,0.98978734,0.00002311136,0.006000663,0.000096522526],"about_ca_topic_score_codex":0.000002103391,"about_ca_topic_score_gemma":3.9307739e-7,"teacher_disagreement_score":0.00567138,"about_ca_system_score_codex":0.000012210737,"about_ca_system_score_gemma":0.000040423944,"threshold_uncertainty_score":0.25355178},"labels":[],"label_agreement":null},{"id":"W2587198615","doi":"10.1007/s12079-017-0375-9","title":"Insights into cellular signalling by G protein coupled receptor transactivation of cell surface protein kinase receptors","year":2017,"lang":"en","type":"review","venue":"Journal of Cell Communication and Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Transactivation; G protein-coupled receptor; Cell biology; Signal transduction; Signalling; Receptor tyrosine kinase; Receptor; Biology; G protein-coupled receptor kinase; Receptor Protein-Tyrosine Kinases; Protein kinase A; Phosphorylation; Biochemistry; Transcription factor","score_opus":0.028085867546717377,"score_gpt":0.2779707609496315,"score_spread":0.24988489340291414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2587198615","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.08209439,0.9003934,0.01639796,0.00001728687,0.000107402106,0.0008791924,0.000008103157,0.0000067760425,0.00009547952],"genre_scores_gemma":[0.1625161,0.8235421,0.01303157,0.0000081165235,0.000116302035,0.000023620998,0.00022163709,0.00008591199,0.00045464482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964552,0.00082674355,0.0016785817,0.00036892056,0.00043256415,0.00023799605],"domain_scores_gemma":[0.99456537,0.000095971634,0.003869364,0.0007438492,0.00053670607,0.00018874386],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013617814,0.00050328847,0.0013921583,0.00017759985,0.00038134656,0.000131861,0.0010166751,0.0006488094,0.000087803186],"category_scores_gemma":[0.00008784953,0.00043719696,0.0005617029,0.0001394832,0.00013004876,0.000045673118,0.00012057143,0.00077165983,0.0000025076663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000077122546,0.00015618262,2.6657935e-7,0.0031768924,0.00011567929,0.0000011607635,0.00024300789,0.00006731116,0.97815263,0.000014750762,0.000053226362,0.017941775],"study_design_scores_gemma":[0.0005205201,0.00035306087,1.1971129e-8,0.0051680584,0.00019040325,0.000002133603,0.00014939123,0.00008790877,0.74832696,0.00007152548,0.2447732,0.00035685286],"about_ca_topic_score_codex":0.00002986974,"about_ca_topic_score_gemma":0.0000022453485,"teacher_disagreement_score":0.24471997,"about_ca_system_score_codex":0.00006539462,"about_ca_system_score_gemma":0.00041120767,"threshold_uncertainty_score":0.99980795},"labels":[],"label_agreement":null},{"id":"W2587290015","doi":"10.1074/jbc.m116.730614","title":"Site-specific O-Glycosylation by Polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-transferase T2) Co-regulates β1-Adrenergic Receptor N-terminal Cleavage","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Novo Nordisk; Magnus Ehrnroothin Säätiö; Sundhed og Sygdom, Det Frie Forskningsråd; Danmarks Grundforskningsfond; National Research Foundation; Medical Research Center Oulu","keywords":"Glycosylation; Proteolysis; Receptor; G protein-coupled receptor; Agonist; Biochemistry; Biology; Gene isoform; Cell biology; HEK 293 cells; N-linked glycosylation; Chemistry; Enzyme; Glycoprotein; Gene","score_opus":0.016732705589336205,"score_gpt":0.2555863522879407,"score_spread":0.23885364669860448,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2587290015","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957733,0.0014811549,0.0012871984,0.00016826694,0.00023853268,0.00010177248,0.00014522934,0.000014577116,0.0007899294],"genre_scores_gemma":[0.9953447,0.0019071753,0.0006903016,0.00009853174,0.0011460953,0.000005117012,0.00035103303,0.00003357417,0.000423486],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979846,0.000083905186,0.0007247268,0.00046157895,0.00031145706,0.00043371937],"domain_scores_gemma":[0.99843794,0.000039399074,0.0005142625,0.00050617015,0.00016936442,0.00033287684],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005030962,0.00037785835,0.00047935065,0.000028697741,0.0003746558,0.00018581326,0.0006693649,0.00057778275,0.0010490741],"category_scores_gemma":[0.00014841773,0.00029511965,0.0004292395,0.00004000949,0.00025747268,0.000026030206,0.00006431184,0.0004150716,0.000017757593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006626763,0.00016707448,0.001869064,0.000026548123,0.000060845054,0.000042634416,0.00002387643,0.000013517233,0.99145395,0.0000064541455,0.003727885,0.0019454883],"study_design_scores_gemma":[0.0012794741,0.0005861557,0.0006882278,0.00005830229,0.000025456982,0.00019079204,0.000058781796,0.000010567992,0.9738018,0.00004102753,0.022882907,0.0003765238],"about_ca_topic_score_codex":0.000008610548,"about_ca_topic_score_gemma":0.0000011686577,"teacher_disagreement_score":0.019155022,"about_ca_system_score_codex":0.000043485295,"about_ca_system_score_gemma":0.00006822589,"threshold_uncertainty_score":0.9999501},"labels":[],"label_agreement":null},{"id":"W2588414667","doi":"10.1074/jbc.m116.763854","title":"Conformational Profiling of the AT1 Angiotensin II Receptor Reflects Biased Agonism, G Protein Coupling, and Cellular Context","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Receptor; Förster resonance energy transfer; Chemistry; Context (archaeology); Biophysics; HEK 293 cells; Biosensor; Functional selectivity; Arrestin; Ligand (biochemistry); Angiotensin II; Biochemistry; Biology; Fluorescence; Physics","score_opus":0.026848253631625817,"score_gpt":0.2539833992760209,"score_spread":0.2271351456443951,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2588414667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99828315,0.0007168053,0.00030197788,0.00027584253,0.00011255548,0.0001207616,0.000015430618,0.0000024894107,0.0001710118],"genre_scores_gemma":[0.99788046,0.00006460095,0.0015008243,0.00006570694,0.00030654183,0.0000024828619,0.000015565456,0.00000748162,0.00015632855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909115,0.000023037695,0.0004165814,0.00014844554,0.000165434,0.00015534523],"domain_scores_gemma":[0.99852014,0.000014576189,0.0008670324,0.00024924727,0.00026606602,0.00008292022],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004576804,0.0001351513,0.00023810522,0.000009809342,0.00030191697,0.00003837341,0.00035660146,0.00026373204,0.00006309006],"category_scores_gemma":[0.0005227598,0.000081361766,0.00017518768,0.000021204192,0.00023144511,0.000008748872,0.00019239758,0.00020710166,4.2104344e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013443141,0.000034658588,0.00056071865,0.00002443385,0.000042037293,0.000001807181,0.000017217899,0.0000122484125,0.99868596,0.000046983987,0.00012047465,0.00031901494],"study_design_scores_gemma":[0.0005505456,0.00026033877,0.00020627274,0.00009454568,0.000011774304,0.00003008633,0.000082507904,0.000074224576,0.9957944,0.00012044412,0.0026669733,0.0001078965],"about_ca_topic_score_codex":0.0000022707086,"about_ca_topic_score_gemma":2.489041e-7,"teacher_disagreement_score":0.002891583,"about_ca_system_score_codex":0.000012041162,"about_ca_system_score_gemma":0.00009927581,"threshold_uncertainty_score":0.33178365},"labels":[],"label_agreement":null},{"id":"W2589970381","doi":"10.3389/fncel.2017.00037","title":"Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease","year":2017,"lang":"en","type":"review","venue":"Frontiers in Cellular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Medical Research Council; Vetenskapsrådet; Hjärnfonden; AFA Försäkring","keywords":"Galanin; Neuroscience; G protein-coupled receptor; Biology; Autoreceptor; Chemistry; Receptor; Neuropeptide; Cell biology; Signal transduction; Biochemistry; Agonist","score_opus":0.092521532125003,"score_gpt":0.31122498532813203,"score_spread":0.21870345320312903,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2589970381","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007860151,0.9673193,0.030552402,0.000100866,0.00057778275,0.00063345383,0.000011112796,0.0000024548506,0.000016602746],"genre_scores_gemma":[0.10354102,0.8958654,0.000237119,0.00014304544,0.00008870853,0.00003203147,0.000025086469,0.000029781542,0.000037828442],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978819,0.00050479546,0.00052320975,0.00053557084,0.0001763431,0.00037817945],"domain_scores_gemma":[0.9989049,0.00005381102,0.00043451303,0.00048930495,0.00000760245,0.000109913344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011439496,0.00023782808,0.0005841313,0.000117725176,0.00021588552,0.00008084509,0.0007194847,0.00011705434,0.0000011133482],"category_scores_gemma":[0.00031459657,0.0001566784,0.00012195387,0.00021288497,0.00034875053,0.000009309271,0.0002631199,0.00033791544,5.7815306e-8],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001368871,0.00021193703,0.010712329,0.006350635,0.000040278497,0.000056253404,0.0016121276,0.02899083,0.021006776,0.0018656389,0.0010438805,0.92797244],"study_design_scores_gemma":[0.00078626117,0.00036164044,0.00012231183,0.010154882,0.000042978758,0.000014373206,0.0016998298,0.18716352,0.0004604767,0.003936409,0.7941787,0.0010785867],"about_ca_topic_score_codex":0.000047312395,"about_ca_topic_score_gemma":0.000025708705,"teacher_disagreement_score":0.92689383,"about_ca_system_score_codex":0.00006472481,"about_ca_system_score_gemma":0.00021875842,"threshold_uncertainty_score":0.638916},"labels":[],"label_agreement":null},{"id":"W2590136671","doi":"10.1073/pnas.1701529114","title":"Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis","year":2017,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":385,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Government of Canada; Lundbeckfonden; National Institutes of Health; Danmarks Frie Forskningsfond; Howard Hughes Medical Institute","keywords":"G protein-coupled receptor; Internalization; Endocytosis; Receptor; Arrestin; Cell biology; Transmembrane protein; Signal transduction; Chemistry; Phosphorylation; Biology; Biophysics; Biochemistry","score_opus":0.03888651271838634,"score_gpt":0.30348103167001583,"score_spread":0.2645945189516295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2590136671","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980872,0.000088376335,0.000030107993,0.00037632222,0.000014275069,0.00008203126,0.000026200893,0.0000018583216,0.0012936242],"genre_scores_gemma":[0.99833864,0.000034019242,0.0015045685,0.000039647268,0.0000486301,0.000002760997,9.4571163e-7,0.000002356463,0.000028448583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999217,0.000004378509,0.000230153,0.00011962466,0.00035210038,0.00007674143],"domain_scores_gemma":[0.99908847,0.000029217124,0.00055091624,0.000011245101,0.0002963023,0.000023882181],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058335887,0.00005889698,0.00010108546,0.00004295209,0.00032247035,0.000028859506,0.00038908204,0.000049502563,0.000008849872],"category_scores_gemma":[0.0007673624,0.000041643354,0.000038578208,0.00006666521,0.00059488363,0.000030017149,0.00013754959,0.00004014954,1.3229192e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006180821,0.000008173043,0.009859127,0.000030037936,0.0000098569935,9.976623e-10,0.000060208,0.000035930156,0.979247,0.01050352,0.000095685624,0.00014430947],"study_design_scores_gemma":[0.00011923537,0.000034956556,0.03298997,0.000045569264,0.000008807808,0.0000024074102,0.00008887166,0.0004989646,0.95874715,0.007313177,0.00010357451,0.000047325637],"about_ca_topic_score_codex":0.000008087136,"about_ca_topic_score_gemma":2.1902649e-7,"teacher_disagreement_score":0.023130843,"about_ca_system_score_codex":0.0000031533957,"about_ca_system_score_gemma":0.000022457909,"threshold_uncertainty_score":0.24802138},"labels":[],"label_agreement":null},{"id":"W2591737845","doi":"10.1523/jneurosci.4345-15.2017","title":"Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness","year":2017,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"National Institute of Mental Health; National Institutes of Health; Brain Research Foundation","keywords":"Neuroscience; Prefrontal cortex; Neurotransmitter; Neuroplasticity; Synaptic plasticity; Potassium channel; Biology; Chemistry; Endocrinology; Receptor; Central nervous system","score_opus":0.026433206578313294,"score_gpt":0.2756635235118535,"score_spread":0.24923031693354022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2591737845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99545646,0.000016032367,0.0043210723,0.00001724115,0.0000948966,0.00006909495,0.000016980026,2.3530117e-7,0.000007989402],"genre_scores_gemma":[0.99976677,0.000049390554,0.00014591287,0.000015094134,0.000014912496,6.6085136e-7,3.968513e-7,0.0000026657685,0.000004177911],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925697,0.000047134483,0.00030006925,0.00011228558,0.00020856848,0.00007496669],"domain_scores_gemma":[0.999416,0.000015080325,0.00034043446,0.0001346051,0.0000663917,0.000027499062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027443506,0.00005845138,0.00013477521,0.000026140158,0.00006342667,0.000016848555,0.00029566977,0.00002906773,0.0000010675208],"category_scores_gemma":[0.00015975459,0.000040652783,0.000047859266,0.000018395709,0.00023086784,0.000023503017,0.00007219772,0.00006917073,6.899001e-9],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000091198475,0.00008514977,0.0037772176,0.000015624368,0.0000021527258,8.808784e-7,0.00015660095,0.00087590434,0.99479204,0.00002708018,8.0212556e-7,0.0001753647],"study_design_scores_gemma":[0.00026103045,0.0007184558,0.13582581,0.000020705846,0.000009017943,0.00003054735,0.00006716515,0.029342072,0.83362454,0.000052594954,0.0000012232329,0.00004681803],"about_ca_topic_score_codex":0.0000044920553,"about_ca_topic_score_gemma":0.00000763616,"teacher_disagreement_score":0.16116746,"about_ca_system_score_codex":0.0000041834023,"about_ca_system_score_gemma":0.00005018906,"threshold_uncertainty_score":0.16577725},"labels":[],"label_agreement":null},{"id":"W2592331661","doi":"10.1124/mol.116.106419","title":"Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells","year":2017,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"HEK 293 cells; Purinergic receptor; Transactivation; P2Y receptor; Receptor; Cell biology; Intracellular; Extracellular; Biology; Apyrase; G protein-coupled receptor; Gs alpha subunit; G protein; Signal transduction; Biochemistry; Gene expression","score_opus":0.0074310746962491115,"score_gpt":0.24668717315992442,"score_spread":0.2392560984636753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2592331661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98697984,0.0018554878,0.008428746,0.00087001943,0.0008646603,0.00047664845,0.000044177927,0.000020434818,0.00045998057],"genre_scores_gemma":[0.99611825,0.0006778016,0.0005206653,0.0007987804,0.00031468505,0.00016911804,0.00021179767,0.00006045592,0.0011284304],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793315,0.00033116722,0.0003721836,0.00061111024,0.00020552249,0.0005468698],"domain_scores_gemma":[0.9989013,0.000036122165,0.0002506008,0.00058918964,0.000084430925,0.0001383363],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005101777,0.00031903898,0.00029268663,0.00007089703,0.0004002384,0.00010179272,0.00077590503,0.00029869933,0.0012823403],"category_scores_gemma":[0.000062507424,0.0002755655,0.00015574366,0.000094430674,0.0001794554,0.00002119141,0.00014417386,0.0002951354,0.00004409951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017223637,0.00018243001,0.0000642664,0.000015184834,0.000088292654,0.000017910079,0.000043439566,0.0016168554,0.9891568,0.000058236026,0.007087705,0.0014966604],"study_design_scores_gemma":[0.00134441,0.0001820467,0.0000204711,0.000011219752,0.000039464114,0.0000068588197,0.000037913807,0.00061934453,0.9178479,0.00004473999,0.079539485,0.00030616493],"about_ca_topic_score_codex":0.00045028885,"about_ca_topic_score_gemma":0.000029262565,"teacher_disagreement_score":0.07245178,"about_ca_system_score_codex":0.00004940853,"about_ca_system_score_gemma":0.000095291245,"threshold_uncertainty_score":0.99996966},"labels":[],"label_agreement":null},{"id":"W2592875668","doi":"10.1021/acs.jmedchem.6b01857","title":"Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-<i>a</i>]pyridine Substructure","year":2017,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Chemistry; Substructure; Pyridine; Stereochemistry; Medicinal chemistry","score_opus":0.006648094694172013,"score_gpt":0.23010758496766348,"score_spread":0.22345949027349146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2592875668","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99703413,0.0008816025,0.0010112389,0.00020733426,0.00013035178,0.000065387285,0.000010180175,0.0000019402128,0.00065782986],"genre_scores_gemma":[0.99745524,0.000102823215,0.0009155406,0.000035947425,0.000932284,0.0000019663264,0.000012027218,0.000020679792,0.0005234628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880373,0.000014102179,0.00040802205,0.00017235764,0.00041713478,0.00018466386],"domain_scores_gemma":[0.9981004,0.000009824957,0.0010613791,0.0004261187,0.00028729325,0.00011497438],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003296658,0.00018157192,0.00034763274,0.000017423943,0.0000996151,0.000039608378,0.0004933598,0.00016195333,0.000053057454],"category_scores_gemma":[0.00023722461,0.00012163689,0.00014318066,0.00003119049,0.00020171703,0.000017040562,0.000064272856,0.00026176995,1.9372678e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006781106,0.000044243243,0.000913597,0.00012829118,0.00010583522,0.000077611374,0.000024738154,0.00005084843,0.99731547,0.00001225962,0.00019198789,0.00045702496],"study_design_scores_gemma":[0.001573927,0.00051693217,0.0005749342,0.00031063193,0.000069024674,0.00045554494,0.00016954353,0.000014613674,0.99506634,0.00007708244,0.0010292,0.00014224966],"about_ca_topic_score_codex":0.000007811273,"about_ca_topic_score_gemma":0.000002152491,"teacher_disagreement_score":0.0022491366,"about_ca_system_score_codex":0.000015033339,"about_ca_system_score_gemma":0.00021069025,"threshold_uncertainty_score":0.49602085},"labels":[],"label_agreement":null},{"id":"W2594006964","doi":"10.1021/jacs.6b12830","title":"In Situ Reconstitution of the Adenosine A<sub>2A</sub> Receptor in Spontaneously Formed Synthetic Liposomes","year":2017,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Division of Chemistry; National Institute of General Medical Sciences; Human Frontier Science Program","keywords":"Chemistry; Transmembrane protein; Receptor; Liposome; Adenosine receptor; G protein-coupled receptor; Biophysics; Ligand (biochemistry); In situ; Vesicle; Adenosine; Adenosine A2A receptor; Proximity ligation assay; Cell surface receptor; Membrane; Biochemistry; Organic chemistry","score_opus":0.007477108553077084,"score_gpt":0.23630719216230767,"score_spread":0.22883008360923057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2594006964","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977419,0.00017587593,0.00006190731,0.0015961127,0.00026215168,0.00008986216,0.0000038292505,9.840785e-7,0.00006738821],"genre_scores_gemma":[0.9985735,0.00041434504,0.00051607966,0.00026637877,0.00019216056,0.0000021916617,7.5545245e-7,0.000009707443,0.000024887708],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905974,0.00006119989,0.00037467363,0.00013282576,0.00019112266,0.00018046389],"domain_scores_gemma":[0.9986647,0.00003070728,0.0008579071,0.00033437693,0.000068612106,0.00004371364],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036360387,0.00011156717,0.00027271517,0.000012789736,0.00008754336,0.000019586567,0.0006164098,0.000091238995,0.0000082398465],"category_scores_gemma":[0.0003481987,0.000067110304,0.00040609177,0.00008798941,0.00043167992,0.000011694924,0.00016891996,0.00028105668,5.603144e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009624239,0.000058848833,0.0013059126,0.000009705316,0.00003250006,0.000001677068,0.00010295297,0.000025965204,0.9961463,0.000011766667,0.0006935304,0.0015145878],"study_design_scores_gemma":[0.00036631786,0.000081121565,0.0013265718,0.000121624485,0.000017671222,0.000090591544,0.00018287348,0.00001834735,0.99700326,0.00018065653,0.0005253236,0.000085649335],"about_ca_topic_score_codex":0.000035196776,"about_ca_topic_score_gemma":0.0000217498,"teacher_disagreement_score":0.0014289384,"about_ca_system_score_codex":0.000084918494,"about_ca_system_score_gemma":0.00012164816,"threshold_uncertainty_score":0.2736679},"labels":[],"label_agreement":null},{"id":"W2594475327","doi":"10.1016/j.vascn.2017.03.001","title":"An improved, high-efficiency assay for assessing serum anticholinergic activity using cultured cells stably expressing M1 receptors","year":2017,"lang":"en","type":"article","venue":"Journal of Pharmacological and Toxicological Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Radioligand; Radioligand Assay; Receptor; Muscarinic acetylcholine receptor; Chemistry; Anticholinergic; Endogeny; Pharmacology; Biochemistry; Biology","score_opus":0.0689621007110169,"score_gpt":0.4406653027450129,"score_spread":0.37170320203399604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2594475327","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.63737255,0.0002232419,0.361095,0.00010062463,0.0009827617,0.00018763731,0.000008804984,0.000007883577,0.000021488433],"genre_scores_gemma":[0.6546346,0.0001363833,0.3442772,0.0001495535,0.000752592,0.000005976874,0.0000016082321,0.000013620763,0.000028436063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973356,0.0009964906,0.0005260801,0.00047922067,0.00018963593,0.00047298725],"domain_scores_gemma":[0.9979189,0.00023360828,0.0009922301,0.000206446,0.00028463738,0.00036415932],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0034983002,0.00030118664,0.0005851679,0.000054579687,0.00088859146,0.0004323969,0.0005342626,0.0004789172,0.00012693767],"category_scores_gemma":[0.0008308648,0.00019347624,0.00025963082,0.000056768422,0.00023217605,0.00009444782,0.00021072896,0.00043931435,1.641593e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037326472,0.00041546708,0.0001507147,0.000015598636,0.00007883064,0.000012430995,0.00001590309,0.00048610373,0.95195735,0.00003378666,0.000041070645,0.04641948],"study_design_scores_gemma":[0.0015134434,0.0019250531,0.0007529977,0.000023395945,0.00018693146,0.00004439332,0.00007379197,0.014119373,0.97936463,0.00054001465,0.001154107,0.00030184907],"about_ca_topic_score_codex":0.000003354402,"about_ca_topic_score_gemma":3.8758674e-7,"teacher_disagreement_score":0.04611763,"about_ca_system_score_codex":0.0000373647,"about_ca_system_score_gemma":0.00008618775,"threshold_uncertainty_score":0.7889732},"labels":[],"label_agreement":null},{"id":"W2597408893","doi":"10.1161/strokeaha.116.015936","title":"Pharmacogenetic Associations of β1-Adrenergic Receptor Polymorphisms With Cardiovascular Outcomes in the SPS3 Trial (Secondary Prevention of Small Subcortical Strokes)","year":2017,"lang":"en","type":"article","venue":"Stroke","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Mace; Medicine; Hazard ratio; Stroke (engine); Internal medicine; Confidence interval; Odds ratio; Myocardial infarction; Cardiology; Proportional hazards model; Percutaneous coronary intervention","score_opus":0.02846190943585889,"score_gpt":0.2797055963959234,"score_spread":0.2512436869600645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2597408893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968787,0.0005912609,0.0012753974,0.000045842316,0.00022321015,0.00037191436,0.00010812125,0.0000029571595,0.0005025991],"genre_scores_gemma":[0.99826115,0.00009983718,0.0011290454,0.000018175479,0.00015392492,0.00003761431,0.00006575074,0.000015279607,0.00021922507],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987857,0.00015955976,0.00033818826,0.00023546116,0.00028762562,0.00019351697],"domain_scores_gemma":[0.99899715,0.00002146282,0.0002819743,0.0005877121,0.00007358509,0.000038112703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055711076,0.000137406,0.0003398595,0.000043262633,0.00010223833,0.000024875639,0.00037637886,0.000116738454,0.00007268718],"category_scores_gemma":[0.000088882465,0.00009805899,0.00037419482,0.000034646833,0.00009126998,0.0000062523836,0.00006154172,0.00011254215,0.0000010172146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014137002,0.00028254406,0.026079101,0.000020414454,0.00079573016,0.0000029714924,0.00009187238,0.00029261544,0.9651381,0.00020418283,0.000035656605,0.0056431056],"study_design_scores_gemma":[0.018548194,0.0014891144,0.038534425,0.000029280372,0.00033417196,0.000004080397,0.00021115848,0.000037523932,0.9398718,0.000077856945,0.00062183273,0.00024055771],"about_ca_topic_score_codex":0.0001072358,"about_ca_topic_score_gemma":0.00007722381,"teacher_disagreement_score":0.0252663,"about_ca_system_score_codex":0.000010950679,"about_ca_system_score_gemma":0.000117477895,"threshold_uncertainty_score":0.39987296},"labels":[],"label_agreement":null},{"id":"W2599483685","doi":"10.1016/j.bbr.2017.03.034","title":"Dissociable effects of systemic and orbitofrontal administration of adrenoceptor antagonists on yohimbine-induced motor impulsivity","year":2017,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; University of British Columbia","keywords":"Yohimbine; Impulsivity; Prazosin; Antagonist; Internal medicine; Propranolol; Endocrinology; Psychology; Alpha-2 adrenergic receptor; Agonist; Neuroscience; Pharmacology; Medicine; Receptor; Developmental psychology","score_opus":0.04584383412581722,"score_gpt":0.36510776124407546,"score_spread":0.31926392711825824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2599483685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99892676,0.00015886402,0.000022619693,0.00011058477,0.00015778137,0.0004560882,0.000046765526,0.0000041972226,0.00011633272],"genre_scores_gemma":[0.9990519,0.00003066108,0.0000924786,0.0000060114226,0.00009704206,0.00003135228,0.00004544703,0.000018596162,0.0006264848],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986179,0.000184535,0.00022559999,0.00031357113,0.00037500856,0.0002833821],"domain_scores_gemma":[0.9989896,0.00008388872,0.00018631597,0.00044151823,0.0001899198,0.00010879428],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007092803,0.00012769466,0.00022648969,0.000057374982,0.00028914108,0.000059143076,0.00028875037,0.00018835749,0.000027049724],"category_scores_gemma":[0.00049574627,0.000115266776,0.00008148877,0.000034506193,0.00014846274,0.000010497703,0.00016742261,0.00016750593,0.0000016871251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002465335,0.00010749927,0.009217282,0.00013710736,0.000019855264,0.00000923499,0.00006667536,1.7722243e-7,0.98814017,0.00014966812,0.00012736212,0.0017784225],"study_design_scores_gemma":[0.00063061167,0.002368983,0.03728081,0.00015598824,0.00000959381,0.000014886639,0.00014725345,0.000015592921,0.9592129,0.000037300575,0.000016606351,0.00010946276],"about_ca_topic_score_codex":0.00035206135,"about_ca_topic_score_gemma":0.000040608542,"teacher_disagreement_score":0.028927272,"about_ca_system_score_codex":0.000027658356,"about_ca_system_score_gemma":0.00012242654,"threshold_uncertainty_score":0.47004429},"labels":[],"label_agreement":null},{"id":"W2600935377","doi":"10.1126/scisignal.aah5756","title":"Structural basis for chemokine recognition by a G protein–coupled receptor and implications for receptor activation","year":2017,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Chemokine receptor; Receptor; CCR1; Cell biology; Chemokine; G protein-coupled receptor; C-C chemokine receptor type 7; Biology; CCL21; C-C chemokine receptor type 6; Chemokine receptor CCR5; Computational biology; Chemistry; Signal transduction; Biochemistry","score_opus":0.026983374807131096,"score_gpt":0.29032895135222375,"score_spread":0.26334557654509266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2600935377","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94207036,0.000046093206,0.055822592,0.0007579501,0.00014877827,0.0009663649,0.00014757598,0.000013968797,0.000026304468],"genre_scores_gemma":[0.9657876,0.000013435944,0.033013202,0.0000786936,0.00029484648,0.00040624227,0.00025429853,0.000019738378,0.00013195508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998871,0.000010926446,0.00018696193,0.0005184185,0.000115403665,0.00029727412],"domain_scores_gemma":[0.9989952,0.000026176938,0.00023798873,0.0002890609,0.00035207142,0.000099545185],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0006392966,0.00013601799,0.00012204892,0.000047086392,0.0014672185,0.00026855513,0.00030552724,0.000099880395,0.00003876595],"category_scores_gemma":[0.0008855083,0.00012858107,0.00006336092,0.0000667744,0.00019393861,0.000054740056,0.000066493325,0.000047172318,9.729056e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006777487,0.000007865705,0.000054692297,0.000019722627,0.000008690577,2.8110207e-9,0.00003432726,0.000005036727,0.98483235,0.00013548214,0.0001766136,0.014657426],"study_design_scores_gemma":[0.0004724597,0.00020860652,0.00010116075,0.000044050932,0.000009961661,6.181015e-7,0.0000744636,0.000821107,0.9951127,0.0015692124,0.0013894818,0.00019613565],"about_ca_topic_score_codex":0.0000150957285,"about_ca_topic_score_gemma":0.0000017140559,"teacher_disagreement_score":0.023717215,"about_ca_system_score_codex":0.000031428055,"about_ca_system_score_gemma":0.000104323546,"threshold_uncertainty_score":0.99983275},"labels":[],"label_agreement":null},{"id":"W2602138971","doi":"","title":"Antagonism of angiotensin 1-7 prevents the therapeutic effects of recombinant human ACE2","year":2015,"lang":"en","type":"article","venue":"PMC","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Angiotensin II; Enos; Internal medicine; Antagonism; Nitric oxide; Endocrinology; Pharmacology; Renin–angiotensin system; Medicine; Antagonist; Endothelial dysfunction; Angiotensin-converting enzyme 2; Angiotensin 1; Nitric oxide synthase; Oxidative stress; Receptor; Blood pressure; Disease","score_opus":0.018580384122806926,"score_gpt":0.26550759953976105,"score_spread":0.24692721541695412,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2602138971","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99710286,0.0016798142,0.0005068947,0.000059951177,0.0003496346,0.00015504388,0.0000012664152,0.0000030403771,0.00014151537],"genre_scores_gemma":[0.9992714,0.0000498269,0.00019637836,0.00004123692,0.000057293313,0.00000485852,0.000009631359,0.000010804709,0.0003586049],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994719,0.000072252486,0.00013706398,0.00011466326,0.00009810079,0.000106038686],"domain_scores_gemma":[0.9995768,0.000009512123,0.00009408326,0.00022767289,0.0000592641,0.000032650998],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021147716,0.000073660514,0.00011862383,0.000013675762,0.000028336506,0.0000040591462,0.0001407564,0.00006744829,0.0000061300525],"category_scores_gemma":[0.000025576492,0.00004875999,0.00007468353,0.000038235343,0.000041131763,0.000001333602,0.00005139349,0.00003725927,0.0000013918818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017137521,0.000047499103,0.00039384273,0.00001780988,0.000041675106,5.6167727e-7,0.00014995728,0.0000041035805,0.99705404,0.00020718125,0.00028944283,0.0017767602],"study_design_scores_gemma":[0.0003895205,0.00043366294,0.0007568589,0.000024399284,0.000022508551,0.0000026909431,0.0000544808,0.000007857711,0.9951099,0.0011268115,0.0020125902,0.000058675963],"about_ca_topic_score_codex":0.000019941888,"about_ca_topic_score_gemma":0.0000013055771,"teacher_disagreement_score":0.0021685257,"about_ca_system_score_codex":0.000004072362,"about_ca_system_score_gemma":0.000027487386,"threshold_uncertainty_score":0.19883746},"labels":[],"label_agreement":null},{"id":"W2602591433","doi":"10.15252/msb.20167430","title":"Systematic protein–protein interaction mapping for clinically relevant human GPCRs","year":2017,"lang":"en","type":"article","venue":"Molecular Systems Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Regina; Princess Margaret Cancer Centre; Public Health Ontario; Institute for Research in Immunology and Cancer; University Health Network; University of Toronto","funders":"H2020 European Research Council; Instituto de Salud Carlos III; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Université Paris Descartes; Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja; American Roentgen Ray Society; Ministerio de Economía y Competitividad; Generalitat de Catalunya; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; International Business Machines Corporation; Institució Catalana de Recerca i Estudis Avançats; Saskatchewan Health Research Foundation; Canadian Institutes of Health Research; Fonds Wetenschappelijk Onderzoek; Canada Foundation for Innovation; Ontario Genomics Institute; Fondation pour la Recherche Médicale; Canadian Cancer Society; University Health Network; Cystic Fibrosis Canada; National Science Foundation; Fundació la Marató de TV3; Association pour la Recherche sur le Cancer","keywords":"Interactome; G protein-coupled receptor; Biology; Druggability; Computational biology; Proteomics; Membrane protein; Integral membrane protein; Protein–protein interaction; Signal transduction; Cell biology; Biochemistry; Membrane","score_opus":0.028854763014913788,"score_gpt":0.3200606568607255,"score_spread":0.2912058938458117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2602591433","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.76884556,0.0007953558,0.22549373,0.00013186193,0.0009530859,0.0031326315,0.000021469456,0.000037874106,0.0005884483],"genre_scores_gemma":[0.995393,0.000009503028,0.0018015656,0.000066691624,0.0004128476,0.0011407874,0.00012692764,0.000056442335,0.0009922674],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975226,0.00034887838,0.00090631703,0.0006793373,0.00011637112,0.0004264962],"domain_scores_gemma":[0.9976283,0.000020134794,0.00091466075,0.0011153105,0.00021310947,0.00010851765],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012294097,0.00028994962,0.00057185214,0.00007492819,0.00052339514,0.0001830391,0.00060863973,0.0004642645,0.0000094122315],"category_scores_gemma":[0.00068711437,0.00025254025,0.00030796297,0.000027168948,0.00009552085,0.000008985066,0.000190126,0.00015143462,0.000019683976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050386938,0.000032080043,0.000054169144,0.0019777375,0.00018421962,0.000007027229,0.00002115531,0.000017297358,0.99220794,0.005269594,0.000052412986,0.00012596394],"study_design_scores_gemma":[0.0016747547,0.00196625,0.00002800998,0.0041366303,0.00008519894,0.00006461867,0.00033308766,0.0011462367,0.9798572,0.0013194173,0.008573543,0.0008150235],"about_ca_topic_score_codex":0.000095790645,"about_ca_topic_score_gemma":0.000009726826,"teacher_disagreement_score":0.22654742,"about_ca_system_score_codex":0.000034003122,"about_ca_system_score_gemma":0.000050579416,"threshold_uncertainty_score":0.99999267},"labels":[],"label_agreement":null},{"id":"W2604335396","doi":"10.3389/fendo.2017.00061","title":"Distinct Conformational Dynamics of Three G Protein-Coupled Receptors Measured Using FlAsH-BRET Biosensors","year":2017,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Québec Consortium for Drug Discovery; McGill University","keywords":"G protein-coupled receptor; Receptor; Intracellular; Agonist; Biophysics; Chemistry; Cell biology; Förster resonance energy transfer; Prostaglandin E2 receptor; Biosensor; Biochemistry; Biology; Fluorescence; Physics","score_opus":0.019077463274151184,"score_gpt":0.2483702373589011,"score_spread":0.2292927740847499,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604335396","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92990667,0.00018296498,0.0677882,0.0000939192,0.0011036932,0.0003141157,0.000033727632,0.000010047451,0.0005666886],"genre_scores_gemma":[0.97785085,0.000030038454,0.021681821,0.000014399827,0.00010438159,0.000019340143,0.0001133646,0.000022595843,0.00016318238],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872565,0.00005459868,0.00038082473,0.0002979409,0.00015447328,0.00038650655],"domain_scores_gemma":[0.9989801,0.0000059665795,0.00035384158,0.0004910206,0.000114374416,0.000054663848],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017509764,0.00018669132,0.00031845988,0.00011634985,0.00017403897,0.00002503051,0.00043665056,0.00019362818,0.00004948627],"category_scores_gemma":[0.00023162579,0.00018748236,0.00010462672,0.000043286775,0.00028256577,0.000013475923,0.00015817933,0.00014487629,0.0000025588552],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007109028,0.00014858854,0.12834577,0.00011700375,0.00035233752,0.000024870707,0.00012615067,0.00081095926,0.849634,0.0065852166,0.0008680533,0.012276147],"study_design_scores_gemma":[0.004815459,0.0007165072,0.0154368915,0.0001818714,0.000075135475,0.000095346615,0.00061485876,0.11714242,0.8442657,0.009371125,0.0061587216,0.0011259911],"about_ca_topic_score_codex":0.000103509556,"about_ca_topic_score_gemma":0.00025563838,"teacher_disagreement_score":0.11633146,"about_ca_system_score_codex":0.000060109665,"about_ca_system_score_gemma":0.00009422853,"threshold_uncertainty_score":0.7645309},"labels":[],"label_agreement":null},{"id":"W2604550827","doi":"10.1073/pnas.1620405114","title":"Conformational equilibria of light-activated rhodopsin in nanodiscs","year":2017,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Eye Institute; Canada Excellence Research Chairs, Government of Canada","keywords":"Rhodopsin; Transducin; Chemistry; G protein-coupled receptor; Transmembrane domain; Conformational isomerism; Biophysics; Crystallography; Lipid bilayer; Transmembrane protein; Site-directed spin labeling; Nuclear magnetic resonance spectroscopy; Receptor; Stereochemistry; Membrane; Biochemistry; Biology; Molecule; Retinal","score_opus":0.038733442591363985,"score_gpt":0.31235295229875204,"score_spread":0.2736195097073881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604550827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99173266,0.000040695842,0.000002083969,0.0006301185,0.000019769213,0.00007269449,0.000008699299,9.932294e-7,0.0074922717],"genre_scores_gemma":[0.99898946,0.000014030113,0.0008316959,0.000039074926,0.000038837727,0.000002502289,3.6844037e-7,0.0000019631489,0.000082048806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991461,0.0000034473499,0.00024313624,0.00011519987,0.0004104892,0.00008164693],"domain_scores_gemma":[0.99928415,0.000011490263,0.0005090446,0.0000104791625,0.00017017117,0.000014687997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007480894,0.00005317996,0.000096709,0.000055523426,0.00011224265,0.00001758591,0.0006265422,0.00007451511,0.000015345104],"category_scores_gemma":[0.0004283172,0.000036686684,0.00004777643,0.0000916889,0.00032960263,0.000042280983,0.00014476923,0.000051009047,2.2617161e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018053077,0.000014855023,0.0020367652,0.000019151501,0.0000059494405,7.946074e-10,0.000041685584,0.000024698049,0.98213005,0.01547894,0.000110106004,0.00011976955],"study_design_scores_gemma":[0.00015432651,0.000036927206,0.014072914,0.000050414168,0.0000017944444,0.0000014087631,0.00006561317,0.00024141009,0.9772714,0.007847145,0.00021457968,0.00004210971],"about_ca_topic_score_codex":0.000005364333,"about_ca_topic_score_gemma":8.2933845e-8,"teacher_disagreement_score":0.012036148,"about_ca_system_score_codex":0.00000637022,"about_ca_system_score_gemma":0.00003796907,"threshold_uncertainty_score":0.14960396},"labels":[],"label_agreement":null},{"id":"W2606091737","doi":"10.1038/ncomms15054","title":"A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":219,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé; Canadian Space Agency; Canadian Institutes of Health Research; McGill University Health Centre; Mitacs; Canada Research Chairs; McGill University","keywords":"Arrestin; Internalization; Endocytosis; Endocytic cycle; G protein-coupled receptor; Cell biology; Clathrin; Receptor; G protein; Enzyme-linked receptor; Chemistry; Biology; Signal transduction; Biochemistry","score_opus":0.029978651997186082,"score_gpt":0.3345346608324139,"score_spread":0.3045560088352278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2606091737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9599292,0.006386566,0.029055376,0.0018380089,0.00039056517,0.00049229036,0.000068290465,0.000018563063,0.0018211033],"genre_scores_gemma":[0.9928908,0.00024133679,0.0063358527,0.00010968664,0.00016280959,0.000005404846,0.00007218815,0.000012340389,0.00016957783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993803,0.00008828595,0.00020526207,0.00014129624,0.00009202006,0.00009283144],"domain_scores_gemma":[0.9983034,0.000050764218,0.0002675546,0.0012235965,0.000106305306,0.000048386064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017715135,0.00009189774,0.00012269725,0.000022509912,0.0003679281,0.00006366597,0.0011306201,0.00016695618,0.000017000244],"category_scores_gemma":[0.00032287833,0.000071949136,0.000058738893,0.000033869397,0.00011097908,0.000007840834,0.0007503472,0.00027016076,9.171554e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010867793,0.000014365158,0.01844101,0.0000124160915,0.00005294118,9.257085e-8,0.00012881728,0.000008978609,0.9735616,0.0028847342,0.0015005096,0.0033836707],"study_design_scores_gemma":[0.0012618697,0.00019892727,0.058252864,0.00053895137,0.00016600813,0.000017111044,0.00017119347,0.0010262987,0.8609285,0.0037459657,0.07323259,0.0004597294],"about_ca_topic_score_codex":0.000044421544,"about_ca_topic_score_gemma":0.000114646,"teacher_disagreement_score":0.11263311,"about_ca_system_score_codex":0.000009964084,"about_ca_system_score_gemma":0.00004680371,"threshold_uncertainty_score":0.29340008},"labels":[],"label_agreement":null},{"id":"W2606395885","doi":"10.1021/acs.biochem.7b00165","title":"Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors","year":2017,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; Canadian Institute for Advanced Research; Arnold and Mabel Beckman Foundation","keywords":"Rhodopsin; Opsin; G protein-coupled receptor; Chemistry; Extracellular; Structural motif; Biophysics; Biology; Signal transduction; Biochemistry; Retinal","score_opus":0.02034419730230822,"score_gpt":0.2722768780231359,"score_spread":0.25193268072082764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2606395885","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967542,0.0018725324,0.00028136288,0.00004246525,0.00008629744,0.0006111055,0.00004834181,0.000013113678,0.00029053527],"genre_scores_gemma":[0.9934256,0.000062494364,0.0017624015,0.000009051262,0.00020689883,0.000078180026,0.00016852944,0.00005468565,0.004232161],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978415,0.00006619901,0.0006871293,0.0006538177,0.00028881084,0.0004625704],"domain_scores_gemma":[0.9979638,0.000008895405,0.0007429043,0.000977987,0.00016870373,0.00013774165],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00062090077,0.0003422002,0.0005442035,0.00008286939,0.0001375619,0.00004167853,0.00065773615,0.00046511454,0.0002751756],"category_scores_gemma":[0.0001626488,0.0003615561,0.00021212848,0.000118060765,0.00021374153,0.00001437588,0.00026010262,0.00017901197,0.0000026187167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014553001,0.0001969834,0.0031890282,0.00062124216,0.000081843435,0.000013281491,0.00003971757,0.0000023653836,0.9954743,0.000011872064,0.00006549332,0.00015837343],"study_design_scores_gemma":[0.001068722,0.000368908,0.00023063773,0.0002248788,0.000023128028,0.000006189257,0.00011366328,0.00014614407,0.997235,0.00012735595,0.00009492622,0.0003604257],"about_ca_topic_score_codex":0.00034621116,"about_ca_topic_score_gemma":0.000013624247,"teacher_disagreement_score":0.003941626,"about_ca_system_score_codex":0.00004363578,"about_ca_system_score_gemma":0.00012459264,"threshold_uncertainty_score":0.99988365},"labels":[],"label_agreement":null},{"id":"W2607095583","doi":"10.1016/j.coph.2017.03.001","title":"Understanding GPCR signaling in the brain- the path to CNS drug discovery","year":2017,"lang":"en","type":"editorial","venue":"Current Opinion in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Institut National de la Recherche Scientifique; Armand Frappier Museum","funders":"","keywords":"G protein-coupled receptor; Calcium signaling; Cell biology; Calcium channel; Voltage-dependent calcium channel; Phosphorylation; Neuroscience; Signal transduction; Calcium; Biology; Drug discovery; N-type calcium channel; Chemistry; T-type calcium channel; Bioinformatics","score_opus":0.07722190508972315,"score_gpt":0.3782840568250483,"score_spread":0.30106215173532513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2607095583","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0038700306,0.0039088177,0.0027370846,0.0025414529,0.9857057,0.0009472518,0.0001407164,0.000009210766,0.00013974748],"genre_scores_gemma":[0.11893184,0.0054320563,0.000028012033,0.00056454964,0.8729547,0.00048649748,0.0011980347,0.00008997039,0.0003143368],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972145,0.00063647726,0.0004816813,0.0007001112,0.00041204016,0.00055518333],"domain_scores_gemma":[0.9985319,0.0005596091,0.00030210815,0.00047818408,0.000057890218,0.00007035526],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001790322,0.00037899305,0.00036660463,0.00014574896,0.0003067307,0.00019527179,0.0013651232,0.00043025622,0.00006289194],"category_scores_gemma":[0.00035057525,0.0002575119,0.0001768444,0.00013262485,0.00011627121,0.000013644062,0.00038448098,0.0011574973,0.000009665109],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011757565,0.00008137712,0.000033911856,0.00012323735,0.000034614208,0.0000029039077,0.00054662285,0.00028760865,0.026863134,0.00017394434,0.97144306,0.0002920333],"study_design_scores_gemma":[0.00096730446,0.00012659248,0.000007112941,0.00030083634,0.000023615368,0.0000019704444,0.00043505797,0.000053783227,0.0037738988,0.00047227825,0.99348885,0.00034870562],"about_ca_topic_score_codex":0.00003204617,"about_ca_topic_score_gemma":0.000032473316,"teacher_disagreement_score":0.115061805,"about_ca_system_score_codex":0.00015891925,"about_ca_system_score_gemma":0.00039172487,"threshold_uncertainty_score":0.9999877},"labels":[],"label_agreement":null},{"id":"W2609885866","doi":"10.1016/j.bbr.2017.04.049","title":"Reduced Vesicular Acetylcholine Transporter favors antidepressant behaviors and modulates serotonin and dopamine in female mouse brain","year":2017,"lang":"en","type":"article","venue":"Behavioural Brain Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Vesicular acetylcholine transporter; Cholinergic; Dopamine; Monoaminergic; Acetylcholine; Serotonin; Neurotransmitter; Dopamine transporter; Antidepressant; Endocrinology; Internal medicine; Striatum; Chemistry; Serotonin transporter; Neuroscience; Pharmacology; Hippocampus; Biology; Dopaminergic; Central nervous system; Medicine; Choline acetyltransferase; Receptor","score_opus":0.0584206375149166,"score_gpt":0.35634716653431925,"score_spread":0.29792652901940264,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2609885866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99746454,0.00049999484,0.000027905531,0.0012591146,0.000044460903,0.0006172857,0.000041686566,0.0000117674535,0.00003324356],"genre_scores_gemma":[0.99734455,0.0002387283,0.0004661019,0.000058770544,0.00006907318,0.00008020824,0.00011179772,0.000046581776,0.0015841586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997832,0.00020206829,0.00030805595,0.0007060182,0.00035042706,0.00060144626],"domain_scores_gemma":[0.99890375,0.00003974843,0.00008231855,0.00064915605,0.00010706526,0.00021798113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014476181,0.00023641763,0.0002778912,0.00015031679,0.00044054457,0.0002492606,0.0003718595,0.00026197592,0.0000529421],"category_scores_gemma":[0.00020424454,0.00021771259,0.00006472032,0.00007119479,0.00034958564,0.000033078304,0.0002839966,0.00039768778,0.0000018058664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008504874,0.000074242904,0.13027146,0.000019971936,0.000011034031,0.00006496168,0.00013181473,0.000006331965,0.86682785,0.000033632987,0.00009440526,0.0023792663],"study_design_scores_gemma":[0.00123935,0.00027955903,0.27824876,0.000051839437,0.000008490308,0.00003123085,0.00022750592,0.00012498174,0.7192879,0.000022705586,0.00021581874,0.0002618898],"about_ca_topic_score_codex":0.0011246541,"about_ca_topic_score_gemma":0.00031543433,"teacher_disagreement_score":0.1479773,"about_ca_system_score_codex":0.000018203646,"about_ca_system_score_gemma":0.000045315803,"threshold_uncertainty_score":0.8878061},"labels":[],"label_agreement":null},{"id":"W2610001687","doi":"10.1139/cjpp-2016-0622","title":"Functional β<sub>2</sub>-adrenoceptors in rat left atria: effect of foot-shock stress","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Isoprenaline; Internal medicine; Chronotropic; Adenylyl cyclase; Endocrinology; Forskolin; Inotrope; Norepinephrine; Antagonist; Chemistry; Stimulation; Receptor; Medicine; Heart rate; Dopamine; Blood pressure","score_opus":0.008126816170963544,"score_gpt":0.24430351762281272,"score_spread":0.23617670145184916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2610001687","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99668866,0.0011863018,0.00003541717,0.00011374378,0.0018242893,0.00009252458,0.000020627742,7.923535e-7,0.000037662394],"genre_scores_gemma":[0.9989315,0.00027497078,0.000018524821,0.00010819023,0.00061283197,0.0000023876826,0.00001664365,0.000011457218,0.000023464192],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990031,0.00020266231,0.00028900284,0.00018417384,0.000049149676,0.00027192727],"domain_scores_gemma":[0.99915856,0.00005366463,0.00033199217,0.00012392314,0.00009435776,0.00023748384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003459184,0.00014702656,0.0003413833,0.0001305701,0.00018928562,0.000010771124,0.00023271365,0.0002386619,0.0005510424],"category_scores_gemma":[0.000064758075,0.00012909845,0.0001161812,0.000023219272,0.00026161023,0.000011796709,0.000037447673,0.0002517188,0.0000017833524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034155953,0.000011602363,0.0120594315,0.000051654242,0.00011234984,0.000022617713,0.000035532852,0.00023471768,0.9848007,0.000020234691,0.0013951269,0.0009144925],"study_design_scores_gemma":[0.0015596256,0.0009121409,0.0070422622,0.000020523752,0.000052684212,0.00006268831,0.000016493732,0.000014889772,0.98917466,0.00016630358,0.0008666013,0.00011115214],"about_ca_topic_score_codex":0.00016972702,"about_ca_topic_score_gemma":0.0014990384,"teacher_disagreement_score":0.0050171693,"about_ca_system_score_codex":0.000020938054,"about_ca_system_score_gemma":0.00033521073,"threshold_uncertainty_score":0.6033528},"labels":[],"label_agreement":null},{"id":"W2611014899","doi":"10.1016/j.alcohol.2017.02.267","title":"A chimeric approach to evaluate the role of corticotropin releasing factor in alcohol use disorder","year":2017,"lang":"en","type":"article","venue":"Alcohol","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Internal medicine; Angiotensin II; Endocrinology; Kidney; Receptor; Renin–angiotensin system; Chemistry; Renal cortex; Endocrine system; Medicine; Hormone; Blood pressure","score_opus":0.03533544826097252,"score_gpt":0.2946624858744921,"score_spread":0.2593270376135196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2611014899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970032,0.00048033407,0.0013397362,0.000053710028,0.00008516589,0.0003666972,0.0000104822775,0.000004569609,0.00065612147],"genre_scores_gemma":[0.9981183,0.00017540519,0.0013999292,0.00007584204,0.000065562795,0.000028494847,0.000016708462,0.000020000858,0.00009980233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990237,0.00006880049,0.00021676357,0.0002969427,0.00015820513,0.00023561045],"domain_scores_gemma":[0.99909186,0.0000120249715,0.000111873356,0.00067288836,0.00005385852,0.000057467212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055019893,0.00013844791,0.00017160829,0.000033623626,0.00015289242,0.00007588806,0.00037610478,0.00008740419,0.00003016863],"category_scores_gemma":[0.00019631154,0.00010092023,0.000088268134,0.000050495317,0.000052846026,0.000009875405,0.00013492876,0.000089475536,0.0000072557027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005002228,0.00006074079,0.051859155,0.0000067991887,0.00004113593,4.7475424e-7,0.00016624824,0.0003474008,0.925976,0.00013240617,0.00001940244,0.021340212],"study_design_scores_gemma":[0.0011056612,0.0001973358,0.3102051,0.00004336815,0.000036231748,0.0000056031836,0.0003305009,0.0033068035,0.67911047,0.00025212628,0.0050632865,0.00034352715],"about_ca_topic_score_codex":0.00051740895,"about_ca_topic_score_gemma":0.000050752504,"teacher_disagreement_score":0.25834596,"about_ca_system_score_codex":0.0000072507896,"about_ca_system_score_gemma":0.00003562657,"threshold_uncertainty_score":0.41154078},"labels":[],"label_agreement":null},{"id":"W2614144704","doi":"","title":"Signaling switch of a vasoactive peptide GPCR: Prototypic chemotaxic mechanism involved in glioma","year":2014,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Vasoactive; Mechanism (biology); Vasoactive intestinal peptide; G protein-coupled receptor; Signal transduction; Cell biology; Chemistry; Neuropeptide; Receptor; Biology; Internal medicine; Medicine; Physics","score_opus":0.010894210879907955,"score_gpt":0.22262116077580868,"score_spread":0.2117269498959007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2614144704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84238786,0.0004528472,0.15349852,0.00033117287,0.00012173052,0.00085163466,0.000023630337,0.00003453929,0.002298079],"genre_scores_gemma":[0.970315,0.00016149833,0.028157583,0.000039184448,0.000043024622,0.00020078896,0.00038248915,0.00006059768,0.0006398386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99560237,0.002215315,0.0006423224,0.0008552435,0.0003293926,0.00035535666],"domain_scores_gemma":[0.9964891,0.00017835113,0.0006481057,0.001391683,0.0011667106,0.00012601537],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0039776606,0.0003688078,0.00049231655,0.00020127319,0.000109796805,0.0000929424,0.00089474587,0.0005307859,0.00009832277],"category_scores_gemma":[0.0005542641,0.000400861,0.00027026658,0.00022946876,0.00010155609,0.000008916165,0.0009716382,0.0004883388,0.0000064884157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043433927,0.00024544954,0.00036087947,0.0002149321,0.00010454543,0.0000018048763,0.0013399096,0.00024757284,0.9888004,0.006963739,0.000030952466,0.0016463976],"study_design_scores_gemma":[0.00059352996,0.0000026938064,0.00016961491,0.0012428256,0.000035792164,0.0000036296271,0.0001462686,0.0055786525,0.98407197,0.00736623,0.00041825778,0.00037056115],"about_ca_topic_score_codex":0.0005610292,"about_ca_topic_score_gemma":0.00055975356,"teacher_disagreement_score":0.12792715,"about_ca_system_score_codex":0.00006271189,"about_ca_system_score_gemma":0.00028988364,"threshold_uncertainty_score":0.9998443},"labels":[],"label_agreement":null},{"id":"W2615145336","doi":"10.1038/cr.2017.72","title":"Molecular assembly of rhodopsin with G protein-coupled receptor kinases","year":2017,"lang":"en","type":"article","venue":"Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; Canada Excellence Research Chairs, Government of Canada; American Asthma Foundation; Ministry of Science and Technology of the People's Republic of China; Van Andel Research Institute","keywords":"Rhodopsin; G protein-coupled receptor; G protein-coupled receptor kinase; Biology; Cell biology; Kinase; Computational biology; Signal transduction; Biochemistry; Retinal","score_opus":0.041151866332905185,"score_gpt":0.33503911500781863,"score_spread":0.29388724867491345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2615145336","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914425,0.0004063098,0.0014446547,0.000086061606,0.00004106979,0.00039595854,0.0000053729786,0.0000052930213,0.0061727683],"genre_scores_gemma":[0.99486256,0.00006712771,0.0022636522,0.000009567085,0.00009537415,0.00005405772,0.000022771714,0.000033448196,0.0025914235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985201,0.00012546832,0.00015260288,0.00036507793,0.00045415515,0.00038264575],"domain_scores_gemma":[0.9984891,0.00001719889,0.000111285684,0.000852988,0.00041438412,0.00011504097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008545812,0.00012389006,0.00015910911,0.0000628149,0.00029529794,0.000095478,0.0005788486,0.00013528275,0.00016025078],"category_scores_gemma":[0.00021179538,0.00010061465,0.00006746626,0.00006511239,0.00021304977,0.0000060777847,0.00024260604,0.00017831656,0.00002181179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018496046,0.00007339164,0.00012830479,0.000056882505,0.00002112502,0.0000111423815,0.000017798122,0.000018499371,0.9979316,0.00022395379,0.00028881725,0.0010435192],"study_design_scores_gemma":[0.00047710878,0.0008056686,0.0000782216,0.000053431253,0.00000413056,0.000001547912,0.00008228583,0.00007843315,0.9940131,0.00006628022,0.004210331,0.00012951535],"about_ca_topic_score_codex":0.00011472342,"about_ca_topic_score_gemma":0.000012908182,"teacher_disagreement_score":0.003921514,"about_ca_system_score_codex":0.000012534439,"about_ca_system_score_gemma":0.00018050865,"threshold_uncertainty_score":0.41029462},"labels":[],"label_agreement":null},{"id":"W2617986317","doi":"10.1177/2472555217705373","title":"High-Throughput Agonist Shift Assay Development for the Analysis of M1-Positive Allosteric Modulators","year":2017,"lang":"en","type":"article","venue":"SLAS DISCOVERY","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Allosteric regulation; Agonist; Allosteric modulator; Partial agonist; Chemistry; Drug discovery; Biophysics; Pharmacology; Intrinsic activity; Receptor; Biochemistry; Biology","score_opus":0.013701749630111393,"score_gpt":0.26240947327396735,"score_spread":0.24870772364385596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2617986317","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86350495,0.0002430684,0.13530827,0.00011523563,0.00035240018,0.00021149014,0.00010584752,0.000003525544,0.0001552296],"genre_scores_gemma":[0.99700105,0.000048609607,0.0018016702,0.00008154018,0.00012703011,0.00003909704,0.00022877997,0.000016810414,0.00065542606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910504,0.000030169516,0.00022664382,0.00030191106,0.00014135288,0.00019487961],"domain_scores_gemma":[0.9990853,0.000037434274,0.00023840353,0.0005476745,0.000057543395,0.000033617893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029179893,0.0001463643,0.00023476697,0.00003783812,0.00044215375,0.00014518375,0.0003642616,0.00009290068,0.000021903446],"category_scores_gemma":[0.00006336866,0.00010355226,0.00025009213,0.000056361125,0.000102346086,0.000014825559,0.00017628873,0.000042666892,0.0000015823838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042384607,0.00021259954,0.007055358,0.000059504302,0.00883071,0.000003595826,0.00074965024,0.0046199886,0.9564198,0.009367966,0.0008210469,0.011435938],"study_design_scores_gemma":[0.00039304906,0.00012448171,0.04470945,0.000017222832,0.0005685259,4.887165e-7,0.00012969252,0.00049984123,0.9492205,0.00035766597,0.0037352052,0.00024389569],"about_ca_topic_score_codex":0.00010557779,"about_ca_topic_score_gemma":0.0001603291,"teacher_disagreement_score":0.1335066,"about_ca_system_score_codex":0.000017699898,"about_ca_system_score_gemma":0.0000843464,"threshold_uncertainty_score":0.42227387},"labels":[],"label_agreement":null},{"id":"W2619680547","doi":"10.1101/142265","title":"Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Hospital for Sick Children; Canadian Institutes of Health Research; John T. Reid Charitable Trusts; Universitetet i Bergen; Scheme for Promotion of Academic and Research Collaboration; University of Toronto; Academy of Finland","keywords":"Interactome; Regulator; AMPA receptor; Endocytic cycle; Cell biology; Excitatory postsynaptic potential; Neuroscience; Biology; Gene knockdown; HEK 293 cells; Small hairpin RNA; Chemistry; Glutamate receptor; Receptor; Inhibitory postsynaptic potential; Gene; Biochemistry; Endocytosis","score_opus":0.013121842958940092,"score_gpt":0.2605286997962504,"score_spread":0.24740685683731028,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2619680547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930235,0.0013167782,0.0035055336,0.00016325922,0.0011331497,0.00050007796,0.00025991283,0.000057587626,0.000040175197],"genre_scores_gemma":[0.9954155,0.00022173801,0.0033435095,0.00013186935,0.00065351,0.00009308284,0.000003007966,0.00011753799,0.00002022043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972656,0.0001962828,0.00064842886,0.0010342197,0.00038120814,0.00047428874],"domain_scores_gemma":[0.9965726,0.0000538264,0.0006632825,0.0014697778,0.0009817545,0.00025872135],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006300179,0.0005258101,0.00066716864,0.0001773418,0.0001793249,0.00017766905,0.00052322354,0.0008965338,0.00011513808],"category_scores_gemma":[0.0018113011,0.00055853673,0.0003028718,0.00009899839,0.00027499045,0.000021368613,0.0007100311,0.0005349497,0.000026177151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008583037,0.00011091395,0.00026889401,0.0003663893,0.0002333348,0.000031084506,0.0000101364585,0.000011434135,0.9963384,0.002295098,0.00024611942,0.0000023615698],"study_design_scores_gemma":[0.00034765774,0.0002517957,0.0022600943,0.0010146663,0.000112012065,1.2070247e-7,0.000006382502,0.00007351208,0.99421275,0.00008438906,0.0010306038,0.0006060262],"about_ca_topic_score_codex":0.000030318788,"about_ca_topic_score_gemma":0.0000013307024,"teacher_disagreement_score":0.0023919982,"about_ca_system_score_codex":0.000078011646,"about_ca_system_score_gemma":0.0005008187,"threshold_uncertainty_score":0.9996866},"labels":[],"label_agreement":null},{"id":"W2620802821","doi":"","title":"The Behavioural Characterization of Dopamine D2 Receptor-related Protein-protein Interactions","year":2013,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto","keywords":"Dopamine receptor D2; Dopamine; Dopamine receptor; Characterization (materials science); Neuroscience; Chemistry; Psychology; Biology; Materials science; Nanotechnology","score_opus":0.008203588040734493,"score_gpt":0.22427634441769934,"score_spread":0.21607275637696485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2620802821","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957205,0.00029373614,0.00042663154,0.000070538495,0.0003400299,0.0005520453,0.00002803401,0.000011800086,0.0025566558],"genre_scores_gemma":[0.88754594,0.00027171234,0.00027985952,0.0000014305712,0.000039826635,0.000004082479,0.001988836,0.000023033706,0.109845296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919975,0.00007188732,0.0001760488,0.00024036916,0.00016004288,0.00015192118],"domain_scores_gemma":[0.99882025,0.0000054150537,0.0005524527,0.00028423322,0.00028619514,0.00005148638],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009863337,0.00017373567,0.00021583619,0.000025744763,0.00019286582,0.000014459894,0.0002815946,0.0002681733,0.005613459],"category_scores_gemma":[0.000018768797,0.00017455251,0.0001684192,0.00003833474,0.00005279953,0.000025078634,0.000052065378,0.00013002331,0.000010623923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015541358,0.000039082242,0.000016060925,0.000039505718,0.000096105105,2.8533339e-7,0.0006493816,9.551596e-7,0.98251283,0.0001266204,0.0000626372,0.016301112],"study_design_scores_gemma":[0.00047461694,0.00037559035,0.009477959,0.00023567892,0.00009405743,0.0000011467539,0.0069569517,0.000056467794,0.9768275,0.000009230374,0.005184835,0.00030594273],"about_ca_topic_score_codex":0.014428149,"about_ca_topic_score_gemma":0.0071157236,"teacher_disagreement_score":0.1081746,"about_ca_system_score_codex":0.0000573095,"about_ca_system_score_gemma":0.0000742152,"threshold_uncertainty_score":0.9952955},"labels":[],"label_agreement":null},{"id":"W2621014178","doi":"10.1523/jneurosci.3250-16.2017","title":"Reduced Slc6a15 in Nucleus Accumbens D2-Neurons Underlies Stress Susceptibility","year":2017,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Institute of Mental Health; National Alliance for Research on Schizophrenia and Depression","keywords":"Nucleus accumbens; Social defeat; Medium spiny neuron; Striatum; Neuroscience; Dopamine receptor D2; Dopamine; Choline acetyltransferase; Neuron; Biology; Chemistry; Cholinergic","score_opus":0.0401776578929494,"score_gpt":0.3136789664284038,"score_spread":0.2735013085354544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2621014178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99795735,0.000052390777,0.00049482944,0.00029797378,0.00088270596,0.00005778681,0.0000065607746,0.0000023406506,0.00024807133],"genre_scores_gemma":[0.9990214,0.0001692485,0.00033512802,0.00015167797,0.00015740354,6.788321e-7,4.4775257e-7,0.000009709644,0.00015426715],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989056,0.00006610724,0.00030366846,0.00025514688,0.00023805424,0.00023144271],"domain_scores_gemma":[0.9989582,0.000013434943,0.0003907031,0.00043206962,0.00009683571,0.00010881552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004097355,0.00010755931,0.00015883229,0.000054279873,0.0002300772,0.00016482305,0.00076609984,0.000064043226,0.000011502674],"category_scores_gemma":[0.000730108,0.000091518,0.00009852994,0.000051558516,0.00018090259,0.000030570693,0.00016836096,0.00018510353,0.000001078426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033158416,0.00006293178,0.0053793425,0.000004740549,0.0000014760873,0.000031300744,0.00003397008,0.00024314423,0.99332565,0.000038224487,0.000089952475,0.0007561134],"study_design_scores_gemma":[0.0004719598,0.0006650165,0.13135502,0.00004037233,0.000006932035,0.00010438828,0.000121872545,0.00024158675,0.8644153,0.00030282297,0.002114515,0.00016024087],"about_ca_topic_score_codex":0.000014255681,"about_ca_topic_score_gemma":0.000051011662,"teacher_disagreement_score":0.12891036,"about_ca_system_score_codex":0.000014776532,"about_ca_system_score_gemma":0.000118533535,"threshold_uncertainty_score":0.37319955},"labels":[],"label_agreement":null},{"id":"W2623838690","doi":"10.1074/jbc.m117.793877","title":"Conformational biosensors reveal allosteric interactions between heterodimeric AT1 angiotensin and prostaglandin F2α receptors","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Allosteric regulation; G protein-coupled receptor; Chemistry; Receptor; Biophysics; Förster resonance energy transfer; Signal transduction; Angiotensin II; Intracellular; Cell biology; Biochemistry; Biology; Fluorescence","score_opus":0.032245524541964624,"score_gpt":0.28102870259482515,"score_spread":0.24878317805286054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2623838690","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983559,0.00027729297,0.00023887455,0.00043005103,0.00021177287,0.000055719367,0.000022868175,0.000004453425,0.0004030146],"genre_scores_gemma":[0.9973322,0.00023992904,0.0012588559,0.0000799751,0.0007654607,0.0000015133371,0.000063893975,0.000008449654,0.00024973456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909914,0.00003510635,0.00039382797,0.0001749409,0.00011956611,0.00017739595],"domain_scores_gemma":[0.99891746,0.000023954764,0.00058335887,0.00018760488,0.00014311928,0.0001444976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002768063,0.00015189516,0.00024943182,0.000021407839,0.00024187533,0.00009121969,0.00023186591,0.00019798316,0.000106537525],"category_scores_gemma":[0.00026590066,0.000108851884,0.00014614906,0.000022231095,0.00015666558,0.000017897995,0.00013028867,0.00022291546,0.0000029100015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105192106,0.000022432354,0.011477302,0.000012520669,0.000075022115,0.000006334297,0.000018469436,0.0000024881301,0.98496354,0.0000019773797,0.0011268241,0.0021878746],"study_design_scores_gemma":[0.0005955389,0.00037419554,0.015159756,0.000064696054,0.00002707857,0.00039660855,0.00009486894,0.000009472019,0.9525559,0.00006738648,0.030437367,0.0002171568],"about_ca_topic_score_codex":0.000002052307,"about_ca_topic_score_gemma":2.4373296e-7,"teacher_disagreement_score":0.032407686,"about_ca_system_score_codex":0.000016400043,"about_ca_system_score_gemma":0.00002604533,"threshold_uncertainty_score":0.44388512},"labels":[],"label_agreement":null},{"id":"W2624248863","doi":"10.1161/res.113.suppl_1.a031","title":"Abstract 031: β-Adrenergic Receptor-Mediated Transactivation Of Epidermal Growth Factor Receptor Decreases Cardiomyocyte Apoptosis Through Differential Activation Of ERK1/2 and Akt","year":2013,"lang":"en","type":"article","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Transactivation; Protein kinase B; Phosphorylation; Epidermal growth factor receptor; Cell biology; Apoptosis; Signal transduction; Biology; Cancer research; Chemistry; Internal medicine; Endocrinology; Receptor; Transcription factor; Medicine; Biochemistry; Gene","score_opus":0.04098691747571159,"score_gpt":0.29616226046002153,"score_spread":0.25517534298430994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2624248863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98714817,0.00011812662,0.011870776,0.00008437762,0.000084561456,0.00047583497,0.000039076996,0.000011526694,0.00016754461],"genre_scores_gemma":[0.99836457,0.00020490009,0.00062539877,0.000010606188,0.00014398475,0.000060724127,0.00053432485,0.000028269842,0.0000272404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814653,0.00022615732,0.00044127935,0.0003811168,0.0005221129,0.00028280908],"domain_scores_gemma":[0.99854827,0.000152718,0.00019740096,0.00023657912,0.00076327886,0.00010174941],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003010706,0.00016665435,0.00026653195,0.00016450838,0.000121996825,0.000040473744,0.00013701033,0.00026160257,0.001108014],"category_scores_gemma":[0.00035610024,0.0001590273,0.00011811919,0.00027259634,0.0001387945,0.000059461447,0.00004037697,0.00016186005,0.0000073665838],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010217417,0.00007540378,0.0031594746,0.00010591815,0.00008903511,4.1377433e-8,0.00015821778,0.00017501885,0.9926406,0.00016747379,0.00014254762,0.0031841027],"study_design_scores_gemma":[0.0005643899,0.00012751095,0.047801908,0.00005545111,0.000008200286,4.8641306e-7,0.00017261136,0.0003578648,0.95040226,0.00027163225,0.000089427645,0.00014824107],"about_ca_topic_score_codex":0.0008398511,"about_ca_topic_score_gemma":0.0000032679734,"teacher_disagreement_score":0.044642434,"about_ca_system_score_codex":0.00003465937,"about_ca_system_score_gemma":0.000093565715,"threshold_uncertainty_score":0.9998051},"labels":[],"label_agreement":null},{"id":"W2624733460","doi":"10.1016/j.pnpbp.2017.06.009","title":"Opiate exposure state controls dopamine D3 receptor and cdk5/calcineurin signaling in the basolateral amygdala during reward and withdrawal aversion memory formation","year":2017,"lang":"en","type":"article","venue":"Progress in Neuro-Psychopharmacology and Biological Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Opiate; Basolateral amygdala; Dopamine; Amygdala; Conditioned place preference; Neuroscience; Psychology; Anhedonia; Internal medicine; Receptor; Medicine","score_opus":0.010418713193274783,"score_gpt":0.27275948297163743,"score_spread":0.2623407697783626,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2624733460","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935735,0.003759989,0.000022596478,0.001401757,0.0006371124,0.00055026653,0.000013208085,0.000013707121,0.000027866381],"genre_scores_gemma":[0.9961303,0.002351422,0.00037262906,0.00076292414,0.00025437845,0.00007514392,0.000019496285,0.000013389312,0.000020336878],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9982358,0.0003406518,0.000376084,0.00057635363,0.000093938776,0.0003771595],"domain_scores_gemma":[0.9993965,0.000051568546,0.00022201816,0.00020852184,0.00002818685,0.000093173054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005559268,0.00026317316,0.00027995088,0.00007436765,0.000389232,0.00010727325,0.00027077293,0.00024947315,0.000019562602],"category_scores_gemma":[0.000043025466,0.00017788543,0.000048536727,0.00005040222,0.00032088588,0.000037962564,0.00018226985,0.0003930639,9.4178415e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029349022,0.00014845814,0.6979883,0.00008343015,0.000026443622,0.000030659365,0.00015260068,0.000013149238,0.29418775,0.000029511197,0.000070222566,0.0043346286],"study_design_scores_gemma":[0.011525974,0.001977814,0.9697317,0.00011166194,0.000031529544,0.00017946791,0.00024454008,0.00026380594,0.013921076,0.0005466853,0.00093815685,0.0005276007],"about_ca_topic_score_codex":0.0000047166623,"about_ca_topic_score_gemma":0.000014106683,"teacher_disagreement_score":0.28026667,"about_ca_system_score_codex":0.0000060519333,"about_ca_system_score_gemma":0.000013006167,"threshold_uncertainty_score":0.7253958},"labels":[],"label_agreement":null},{"id":"W2624758059","doi":"10.1016/bs.ai.2017.05.005","title":"Adhesion GPCRs in Regulating Immune Responses and Inflammation","year":2017,"lang":"en","type":"review","venue":"Advances in immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":71,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Genome Canada","keywords":"Biology; G protein-coupled receptor; Cell biology; Signal transduction; Immune system; Inflammation; Innate immune system; Transmembrane protein; Receptor; Cell adhesion; Effector; Immunology; Cell; Genetics","score_opus":0.03184827432116668,"score_gpt":0.35250053071088155,"score_spread":0.3206522563897149,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2624758059","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0060649156,0.99298936,0.000056423985,0.000008673137,0.00034111482,0.0003048253,0.000004203664,0.0000062858594,0.00022417291],"genre_scores_gemma":[0.0017327111,0.99703324,0.00066103204,0.000003363056,0.0001100919,0.00008252405,0.00011153463,0.000030187295,0.00023531383],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983597,0.00029879037,0.00059616024,0.00043014242,0.000057617763,0.0002576246],"domain_scores_gemma":[0.9989523,0.00007923549,0.0004694063,0.00045838882,0.000023810948,0.000016843902],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048351198,0.00025842327,0.00078144384,0.000212997,0.000085228756,0.000024120462,0.00027863757,0.00050762657,0.000011760969],"category_scores_gemma":[0.0004297891,0.00023757826,0.000101638616,0.00007151495,0.000115545736,0.000018722942,0.00022570034,0.000268616,0.000003972551],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005607148,0.0000072565736,0.00002398706,0.00064045325,0.000018390616,0.0000066511298,0.0000231957,0.0000050861386,0.015194512,0.00018751093,8.249079e-7,0.98383605],"study_design_scores_gemma":[0.00034261093,0.00015882052,0.000049648374,0.0038811003,0.000021043506,0.000046125933,0.000035225068,0.000004558197,0.0047434377,0.00038620914,0.990048,0.00028325213],"about_ca_topic_score_codex":0.000018976649,"about_ca_topic_score_gemma":0.00007512537,"teacher_disagreement_score":0.99004716,"about_ca_system_score_codex":0.00003556915,"about_ca_system_score_gemma":0.000091255206,"threshold_uncertainty_score":0.96881604},"labels":[],"label_agreement":null},{"id":"W2626367447","doi":"10.1213/ane.0000000000002178","title":"Comments on “Effects of Obesity and Leptin Deficiency on Morphine Pharmacokinetics in a Mouse Model” by Dalesio et al, Anesth Analg. 2016;123:1611–1617","year":2017,"lang":"en","type":"letter","venue":"Anesthesia & Analgesia","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Pharmacokinetics; Morphine; Leptin; Obesity; Volume of distribution; Analysis of variance; Significant difference; Internal medicine; Endocrinology","score_opus":0.012135970626030586,"score_gpt":0.2619352855767735,"score_spread":0.2497993149507429,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2626367447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.952231,0.0013694587,0.00031024066,0.045163713,0.000060265378,0.0006457066,0.000058676043,0.000021039708,0.00013991552],"genre_scores_gemma":[0.65136474,0.0055263317,0.00045566665,0.3377587,0.00033710082,0.000086500164,0.0017193503,0.00021974737,0.0025318402],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969934,0.00029478327,0.0005340725,0.0010380043,0.00053498585,0.0006047235],"domain_scores_gemma":[0.99814504,0.00008616644,0.0005606727,0.0009852451,0.00008932954,0.00013357034],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045123108,0.0007208309,0.0007980435,0.0002358399,0.00016492548,0.0000843091,0.0007168754,0.00074706005,0.000018823199],"category_scores_gemma":[0.00004908484,0.0006719347,0.00021968786,0.00009056455,0.00016197475,0.000013731315,0.00010591154,0.00081174576,0.000008932739],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015723483,0.00039896974,0.0007327231,0.00023778934,0.00007391879,0.00054238085,0.000052954838,0.00039346516,0.26634887,0.00002880333,0.7307315,0.0003014286],"study_design_scores_gemma":[0.003360723,0.0030777294,0.0009373877,0.0007928185,0.00024123339,0.00016860441,0.00001556217,0.0026105412,0.654759,0.00015064428,0.33193183,0.0019539238],"about_ca_topic_score_codex":0.00017574514,"about_ca_topic_score_gemma":0.000009826732,"teacher_disagreement_score":0.39879963,"about_ca_system_score_codex":0.00003776466,"about_ca_system_score_gemma":0.00011190892,"threshold_uncertainty_score":0.9995732},"labels":[],"label_agreement":null},{"id":"W2626406025","doi":"10.1021/acs.biochem.7b00271","title":"Expanding the Scope of Electrophiles Capable of Targeting K-Ras Oncogenes","year":2017,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; National Cancer Institute; Government of Canada; Stand Up To Cancer; Entertainment Industry Foundation; American Cancer Society; Howard Hughes Medical Institute","keywords":"Electrophile; Nucleophile; Covalent bond; Chemistry; Cysteine; Combinatorial chemistry; Amino acid; Stereochemistry; Biochemistry; Enzyme; Organic chemistry","score_opus":0.011126221334416412,"score_gpt":0.2636841168732609,"score_spread":0.25255789553884445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2626406025","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928095,0.0045597362,0.00029812308,0.000037388396,0.00009051586,0.00006478194,0.000012806159,0.0000037964378,0.0021234027],"genre_scores_gemma":[0.99799144,0.0005497918,0.0007467743,0.000013342512,0.00027951767,0.0000068390345,0.000026493857,0.000015176658,0.00037065006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925166,0.000016314585,0.00022008955,0.00020849417,0.00012372693,0.0001796997],"domain_scores_gemma":[0.99901533,0.000010157485,0.00031928968,0.0005242555,0.000094364026,0.000036605736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024013614,0.00011592273,0.00015316567,0.00001006006,0.00021691142,0.000025061148,0.00045784106,0.00012085946,0.000054756674],"category_scores_gemma":[0.00019056095,0.0000878378,0.00010934537,0.000023190638,0.00014144939,0.0000032675364,0.00014589097,0.000058470163,9.13941e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027602087,0.000018542143,0.00047384496,0.00005591759,0.00003725087,5.3620965e-7,0.00001608309,0.00001238254,0.9981479,0.000027044773,0.00050686504,0.0006760111],"study_design_scores_gemma":[0.00016771955,0.00005906612,0.00006996466,0.000046272842,0.00001281591,0.0000034807745,0.00010568101,0.000008886599,0.9986296,0.000060786228,0.00073347415,0.00010224038],"about_ca_topic_score_codex":0.000045966288,"about_ca_topic_score_gemma":0.0000017389531,"teacher_disagreement_score":0.005181965,"about_ca_system_score_codex":0.0000069384246,"about_ca_system_score_gemma":0.000077599725,"threshold_uncertainty_score":0.35819215},"labels":[],"label_agreement":null},{"id":"W2652277709","doi":"","title":"Raised blood pressure in second generation offspring of protein restricted rat dams.","year":2004,"lang":"en","type":"article","venue":"Research Portal (King's College London)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Offspring; Blood pressure; Andrology; Medicine; Internal medicine; Biology; Physiology; Genetics; Pregnancy","score_opus":0.024857907759516323,"score_gpt":0.29562985343089343,"score_spread":0.2707719456713771,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2652277709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948283,0.0017086889,0.00018570048,0.00007231848,0.00009843429,0.0010797468,0.000047500074,0.000013565862,0.0019657323],"genre_scores_gemma":[0.99644107,0.000096560674,0.0010939249,0.000018466406,0.00026062605,0.00013784031,0.00012528936,0.000038482,0.0017877476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99758834,0.00022666327,0.0004931429,0.00054588943,0.0005974098,0.00054856396],"domain_scores_gemma":[0.9989486,0.000020786381,0.0001366284,0.00043406684,0.00032259114,0.0001373777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091488264,0.00019203605,0.000273133,0.000274193,0.00014943548,0.000044329543,0.00031621347,0.00027625708,0.0003464105],"category_scores_gemma":[0.0003051666,0.00019417524,0.000104105995,0.000580843,0.00009620378,0.000019604757,0.00018215318,0.0003690567,0.0000042430074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000137936,0.00019276426,0.00034523383,0.00008899441,0.000078651625,0.00009525217,0.000056973215,0.00063600723,0.99604416,0.0019995065,0.00016484302,0.00015966978],"study_design_scores_gemma":[0.0023263549,0.00051179435,0.00037953118,0.00010564507,0.000013711633,0.00001541225,0.000106547675,0.00017703138,0.99121684,0.00026162295,0.0046837204,0.00020181126],"about_ca_topic_score_codex":0.00017257867,"about_ca_topic_score_gemma":0.00069793774,"teacher_disagreement_score":0.0048273513,"about_ca_system_score_codex":0.000017907649,"about_ca_system_score_gemma":0.0004987812,"threshold_uncertainty_score":0.7918237},"labels":[],"label_agreement":null},{"id":"W2671437461","doi":"10.1016/j.yjmcc.2017.06.007","title":"Cardiomyocyte specific overexpression of a 37 amino acid domain of regulator of G protein signalling 2 inhibits cardiac hypertrophy and improves function in response to pressure overload in mice","year":2017,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Pressure overload; Regulator of G protein signaling; RGS2; Muscle hypertrophy; Internal medicine; Endocrinology; Atrial natriuretic peptide; G protein; Cardiac function curve; Transgene; Chemistry; Biology; Cell biology; Heart failure; Receptor; Cardiac hypertrophy; Medicine; Biochemistry; GTPase-activating protein","score_opus":0.005688586202028701,"score_gpt":0.2024109526291484,"score_spread":0.1967223664271197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2671437461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97941905,0.016888987,0.0032357732,0.000022946093,0.00010745742,0.00027918778,0.00001534863,8.081499e-7,0.000030439413],"genre_scores_gemma":[0.998319,0.00030255746,0.0012394565,0.000007085338,0.00009119293,0.0000059380727,0.0000032967866,0.000018075923,0.000013433509],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982754,0.00044926102,0.00060915406,0.0002745257,0.00020425186,0.00018742129],"domain_scores_gemma":[0.99884504,0.000020364685,0.0005837135,0.00029876368,0.00016890503,0.00008320562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011594334,0.00017431648,0.00074047176,0.00017002509,0.00003779711,0.000012875858,0.00016765023,0.00026232714,0.0000015734728],"category_scores_gemma":[0.0001324277,0.00015700403,0.00024095154,0.000061002112,0.00011924847,0.000015909505,0.00015454153,0.00016599202,5.637152e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0040699053,0.00002548723,0.0009663707,0.00010599799,0.00016731647,0.000033203418,0.00012254406,0.00046847644,0.9930167,0.00004034867,0.000006860918,0.0009767719],"study_design_scores_gemma":[0.0012968078,0.0012860002,0.0043778373,0.00027835174,0.000054467564,0.000029534378,0.0001867146,0.0000107859105,0.9914185,0.00016966442,0.0007536688,0.00013766937],"about_ca_topic_score_codex":0.000021337157,"about_ca_topic_score_gemma":0.0000010148287,"teacher_disagreement_score":0.018899912,"about_ca_system_score_codex":0.000012116233,"about_ca_system_score_gemma":0.000068519046,"threshold_uncertainty_score":0.6402438},"labels":[],"label_agreement":null},{"id":"W2692981981","doi":"10.1038/ncomms15884","title":"Hypoxia-induced mobilization of NHE6 to the plasma membrane triggers endosome hyperacidification and chemoresistance","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Endosome; Intracellular; Extracellular; Cell biology; Hypoxia (environmental); Chemistry; Cytoplasm; Endocytosis; Receptor; Biology; Biochemistry; Biophysics","score_opus":0.02382276937263766,"score_gpt":0.2955861365158571,"score_spread":0.2717633671432194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2692981981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926951,0.001970327,0.0003887767,0.003335484,0.00012265281,0.00033146248,0.00002449211,0.000008381412,0.0011233333],"genre_scores_gemma":[0.99532855,0.0010653305,0.0031327775,0.00013255674,0.000052054456,0.000048497575,0.00009071931,0.000011409768,0.00013810572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994336,0.000059315753,0.00015454873,0.0001670846,0.00009727789,0.00008821822],"domain_scores_gemma":[0.99776196,0.000039400384,0.00016256479,0.0018360454,0.00015919618,0.000040844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024283276,0.000083322964,0.000096748445,0.000028302169,0.00049492903,0.000047138976,0.0008650203,0.00016849521,0.0000057496195],"category_scores_gemma":[0.00038726552,0.00006625231,0.000035441823,0.000057800982,0.000074672746,0.000008536552,0.00021306843,0.00017110765,0.0000022162833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022141274,0.000024710595,0.00013787582,0.000005938571,0.000016287344,3.4288703e-8,0.00008295999,0.00001652085,0.9937538,0.002789218,0.00020093267,0.0029496106],"study_design_scores_gemma":[0.0002578688,0.000048158727,0.0035134002,0.000015035053,0.000019112558,0.000002595078,0.000117719304,0.00038929973,0.96719956,0.00006586868,0.028273031,0.00009836706],"about_ca_topic_score_codex":0.000014931611,"about_ca_topic_score_gemma":0.00018136177,"teacher_disagreement_score":0.028072098,"about_ca_system_score_codex":0.000007964014,"about_ca_system_score_gemma":0.000030948206,"threshold_uncertainty_score":0.3806644},"labels":[],"label_agreement":null},{"id":"W2715391917","doi":"10.1111/jnc.14105","title":"Vesicular acetylcholine transporter (<scp>VAC</scp>hT) over‐expression induces major modifications of striatal cholinergic interneuron morphology and function","year":2017,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Western University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Fédération pour la Recherche sur le Cerveau; Université Pierre et Marie Curie; Centre National de la Recherche Scientifique; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Labex; Agence Nationale de la Recherche","keywords":"Vesicular acetylcholine transporter; Choline acetyltransferase; Cholinergic; Acetylcholine; Neuroscience; Cholinergic neuron; Striatum; Biology; Cell biology; Endocrinology; Internal medicine; Dopamine; Medicine","score_opus":0.01448771247759529,"score_gpt":0.2545653486305504,"score_spread":0.24007763615295513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2715391917","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972074,0.00048846187,0.0017567916,0.000059930408,0.00029601168,0.00005957754,0.00002284897,0.0000035414037,0.000105418636],"genre_scores_gemma":[0.99853617,0.00042318946,0.0003006173,0.000059490005,0.00045595728,0.0000026006453,0.000028648565,0.000022013326,0.00017129739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988823,0.000034178804,0.0004749922,0.0002596609,0.00018676507,0.0001621226],"domain_scores_gemma":[0.99844956,0.000019213381,0.00085598044,0.00039250872,0.00016122674,0.000121501165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017960454,0.00017128585,0.00025545302,0.00004664278,0.000117250485,0.000044802757,0.0003549122,0.00021234584,0.00001826475],"category_scores_gemma":[0.00021449175,0.00015013748,0.00015954225,0.000026456328,0.000090719725,0.000026656857,0.00008248868,0.00027449772,4.1109948e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009307176,0.00008301403,0.00077552086,0.000040653398,0.000045573135,0.00001338577,0.00003195208,0.00007157698,0.9981575,0.0000039775737,0.00040014545,0.0002836074],"study_design_scores_gemma":[0.0010879831,0.00028976446,0.019415107,0.000056418412,0.00007497419,0.0001554774,0.00006527179,0.0000383758,0.97739935,0.000041266438,0.0013092363,0.00006678855],"about_ca_topic_score_codex":0.0000035851228,"about_ca_topic_score_gemma":5.058709e-7,"teacher_disagreement_score":0.020758186,"about_ca_system_score_codex":0.000006633919,"about_ca_system_score_gemma":0.000052807143,"threshold_uncertainty_score":0.6122429},"labels":[],"label_agreement":null},{"id":"W2734722856","doi":"10.1016/j.pharmthera.2017.07.002","title":"Pharmacology of human trace amine-associated receptors: Therapeutic opportunities and challenges","year":2017,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":229,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Russian Science Foundation","keywords":"Pharmacology; TRACE (psycholinguistics); Receptor; Chemistry; Medicine; Biochemistry","score_opus":0.3138377505589531,"score_gpt":0.42173314615166163,"score_spread":0.10789539559270855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2734722856","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011763306,0.9954131,0.000012425441,0.00029515137,0.00183166,0.0007893924,0.00008468867,0.000035557357,0.000361659],"genre_scores_gemma":[0.0017147876,0.9953152,0.000037701982,0.00047404907,0.0007766487,0.00017614105,0.00023019513,0.00015015276,0.00112513],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9967724,0.00087167753,0.0008346529,0.00074365915,0.0001891276,0.00058845105],"domain_scores_gemma":[0.9978311,0.00013071833,0.0012459002,0.00044953404,0.00018834184,0.00015441573],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007224755,0.0007431696,0.0018551822,0.00019717395,0.00032681544,0.000034677014,0.0008113211,0.0010811538,0.00033158247],"category_scores_gemma":[0.0000065199483,0.00067382294,0.0004812585,0.000059279104,0.0005691304,0.000010976596,0.00026434386,0.0005171658,0.0000051778043],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052743933,0.00033295617,0.0000028401782,0.003185947,0.0054213726,0.000020057212,0.00020422606,6.070771e-7,0.07313448,0.000121822275,0.0008014112,0.9167215],"study_design_scores_gemma":[0.0008410069,0.00077905494,0.0000014687251,0.00047277703,0.0047165225,0.000040819585,0.000110478395,0.0000054058205,0.014584685,0.00005238351,0.9778032,0.00059222087],"about_ca_topic_score_codex":0.0000065126387,"about_ca_topic_score_gemma":0.0000070777105,"teacher_disagreement_score":0.9770018,"about_ca_system_score_codex":0.000047592675,"about_ca_system_score_gemma":0.0002852464,"threshold_uncertainty_score":0.9995713},"labels":[],"label_agreement":null},{"id":"W2734944829","doi":"","title":"Delineation of the Molecular and Genetic Role of Teneurin C-terminal Associated Peptide-1 (TCAP-1) in Cytoskeletal Development and Neuroprotection Against Stress","year":2014,"lang":"en","type":"dissertation","venue":"Library and Archives Canada (Government of Canada)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Neuroprotection; Filopodia; Cytoskeleton; Biology; Cell biology; Peptide; Actin; Genetics; Neuroscience; Biochemistry; Cell","score_opus":0.0014764275224075378,"score_gpt":0.13834199776504708,"score_spread":0.13686557024263954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2734944829","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99814266,0.00045840643,0.00005173992,0.00002244881,0.000055317327,0.0001604811,0.000043226188,7.9107105e-7,0.0010649081],"genre_scores_gemma":[0.99897766,0.00015229902,0.0002931167,0.000042632375,0.000013850402,0.0000074944287,0.0000794235,0.000015662585,0.00041786177],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887335,0.00007036345,0.0002976242,0.00019849159,0.0004487896,0.0001113994],"domain_scores_gemma":[0.99955195,0.000015585561,0.0002844506,0.00009479784,0.0000024328408,0.00005077103],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00001364912,0.00014331407,0.0001885821,0.000021270036,0.00004973293,0.0000064514065,0.00008798525,0.00006391872,0.0000014652699],"category_scores_gemma":[0.000007716763,0.00012852583,0.00002158138,0.000033071377,0.000027577376,0.0000067273063,0.000056939814,0.000085193606,1.1881356e-10],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012689755,0.000014327518,0.008564969,0.00021265818,0.000036026846,0.0000040492196,0.000052635056,0.00020580257,0.9792697,0.00015583161,0.0000019475535,0.011355149],"study_design_scores_gemma":[0.00020245819,0.000072144925,0.07996933,0.00018070926,0.0000151818895,0.0000017227096,0.0005416983,0.0006216427,0.918007,0.00004132848,0.00023133979,0.00011539662],"about_ca_topic_score_codex":0.00060867134,"about_ca_topic_score_gemma":0.016487611,"teacher_disagreement_score":0.07140437,"about_ca_system_score_codex":0.0000028900206,"about_ca_system_score_gemma":0.00044156724,"threshold_uncertainty_score":0.9200474},"labels":[],"label_agreement":null},{"id":"W2735535979","doi":"10.1111/ejn.13646","title":"<scp>GPR</scp>88 in A<sub>2A</sub> receptor‐expressing neurons modulates locomotor response to dopamine agonists but not sensorimotor gating","year":2017,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Alcohol Abuse and Alcoholism; Centre National de la Recherche Scientifique; Université de Strasbourg; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; Foundation for the National Institutes of Health","keywords":"Quinpirole; Sensory gating; Prepulse inhibition; Nucleus accumbens; Neuroscience; Amphetamine; Knockout mouse; Gating; Dopamine Uptake Inhibitors; Dopaminergic; Rotarod performance test; Agonist; Psychology; Dopamine; Pharmacology; Chemistry; Schizophrenia (object-oriented programming); Medicine; Receptor; Endocrinology; Internal medicine; Psychiatry","score_opus":0.02254876171081868,"score_gpt":0.25912641972475753,"score_spread":0.23657765801393885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2735535979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995997,0.00006080617,0.0021183372,0.000362869,0.0010746279,0.0001685806,0.000017166658,0.000011487056,0.00018912437],"genre_scores_gemma":[0.9965183,0.0000586259,0.0019181728,0.0005057362,0.00049608527,0.0000017892187,0.0000013583808,0.000062477404,0.00043745944],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99703157,0.00080427155,0.0006628449,0.000511255,0.00044672503,0.00054331974],"domain_scores_gemma":[0.99793327,0.00008563897,0.00077942316,0.00064471253,0.0001895363,0.00036744794],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021239314,0.00028491806,0.00029575345,0.00017683588,0.0005669148,0.00048921484,0.0011926522,0.000053576416,0.000003031976],"category_scores_gemma":[0.004933995,0.00026750017,0.00015255749,0.00013698718,0.00019228055,0.000061812556,0.00044169565,0.00038162663,0.000019179184],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017305603,0.00005084,0.00016717847,0.000007894311,0.0000031790114,0.0002828166,0.00011298743,0.0009073562,0.99541765,0.0000017928047,0.00028923282,0.002586014],"study_design_scores_gemma":[0.000586672,0.0010309775,0.034193244,0.00014281861,0.000006006654,0.00017821747,0.00007109254,0.00026193407,0.95372075,0.0000030204642,0.009661991,0.0001432621],"about_ca_topic_score_codex":0.0000025156662,"about_ca_topic_score_gemma":0.0000011345853,"teacher_disagreement_score":0.041696887,"about_ca_system_score_codex":0.000029891322,"about_ca_system_score_gemma":0.00011101953,"threshold_uncertainty_score":0.9999777},"labels":[],"label_agreement":null},{"id":"W2738049143","doi":"10.1385/1-59259-087-x:341","title":"Measurement of Intracellular Free Calcium Ion Concentration in Vascular Smooth Muscle Cells: Fluorescence Imaging of Cytosolic Calcium","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Second messenger system; Vascular smooth muscle; Phosphatidylinositol; Intracellular; Inositol trisphosphate; Cell biology; Phospholipase C; Inositol; Endoplasmic reticulum; Diacylglycerol kinase; Cytosol; Calcium; Calcium in biology; Ryanodine receptor; Chemistry; Biology; Receptor; Signal transduction; Endocrinology; Biochemistry; Protein kinase C; Smooth muscle","score_opus":0.03399388987539709,"score_gpt":0.24441788885774712,"score_spread":0.21042399898235004,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2738049143","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9474979,0.013518107,0.033893462,0.0000051018237,0.00036418374,0.00066358433,0.00001351811,0.00001539568,0.0040287194],"genre_scores_gemma":[0.9990694,0.000111130714,0.0006818647,0.000014522231,0.000052070158,0.000019352488,0.000008312052,0.000020403622,0.000022974295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985885,0.0001509849,0.0003959742,0.0003016801,0.00031882006,0.00024404426],"domain_scores_gemma":[0.99916893,0.000004672615,0.00017140662,0.0004405058,0.00015951497,0.00005494543],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050541986,0.0001551265,0.00020996541,0.000038668313,0.00004059198,0.000013496727,0.0002166613,0.000096895834,0.000018093138],"category_scores_gemma":[0.000046537207,0.00015990043,0.00010307711,0.000021357731,0.00007727001,0.0000052982145,0.000058013014,0.000088641704,3.234848e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016533793,0.00005310318,0.000033611876,0.00007915662,0.000023018818,0.0000022223874,0.00020095789,0.0002687396,0.99556446,0.0015808636,0.00004293186,0.002134392],"study_design_scores_gemma":[0.00071305933,0.00007020411,0.0001469994,0.0000847977,0.000028360748,2.90256e-7,0.00006965122,0.00042394467,0.99448687,0.00013143446,0.0036879505,0.00015642779],"about_ca_topic_score_codex":0.0003198248,"about_ca_topic_score_gemma":0.00003420423,"teacher_disagreement_score":0.051571444,"about_ca_system_score_codex":0.000024054156,"about_ca_system_score_gemma":0.00006302598,"threshold_uncertainty_score":0.652055},"labels":[],"label_agreement":null},{"id":"W2739933313","doi":"10.1016/j.cell.2017.07.002","title":"Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors","year":2017,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":453,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Ministry of Science and Technology of the People's Republic of China; National Eye Institute; American Asthma Foundation; National Institute of General Medical Sciences; Canadian Institute for Advanced Research","keywords":"Arrestin; Rhodopsin; G protein-coupled receptor; Phosphorylation; Biology; Cell biology; Receptor; Internalization; G protein-coupled receptor kinase; Signal transduction; Biochemistry; Biophysics","score_opus":0.02395762783700503,"score_gpt":0.277589282906739,"score_spread":0.25363165506973395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2739933313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96143305,0.00036160377,0.036811836,0.000040970397,0.00026946672,0.000841066,0.000024262097,0.000005313464,0.00021240166],"genre_scores_gemma":[0.9948556,0.00005257793,0.0014655378,0.00000809272,0.00007446625,0.00018271712,0.00017104993,0.000013483473,0.0031765208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944097,0.000013558711,0.00018681119,0.00019190063,0.00006814202,0.0000985954],"domain_scores_gemma":[0.99928766,0.0000051255406,0.00029022363,0.00030283423,0.000084693704,0.000029430774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024739365,0.00007409509,0.00008535719,0.000010497585,0.00014145052,0.000032643857,0.0001556444,0.000083819534,0.00003279085],"category_scores_gemma":[0.00007889694,0.00007234766,0.00005536744,0.00001002695,0.000029739247,0.000003873343,0.000026199094,0.000022600956,0.00000342035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004736727,0.000033856562,0.00006758516,0.0000282282,0.0000082587785,2.9622647e-8,0.000021169713,0.00001388719,0.9970274,0.000043761855,0.001148943,0.0015595295],"study_design_scores_gemma":[0.00033197133,0.00012541401,0.000049336188,0.000011459866,0.0000094315155,9.081157e-8,0.00002720133,0.00047846264,0.98507094,0.00019864916,0.013613942,0.00008310609],"about_ca_topic_score_codex":0.000013800006,"about_ca_topic_score_gemma":0.000002576955,"teacher_disagreement_score":0.0353463,"about_ca_system_score_codex":0.000008397844,"about_ca_system_score_gemma":0.000021505131,"threshold_uncertainty_score":0.29502523},"labels":[],"label_agreement":null},{"id":"W2743757905","doi":"","title":"Alpha-1A adrenergic (ADRA1A) and serotonin 6 (HTR6) receptor gene polymorphisms and clinical response to clozapine","year":2001,"lang":"en","type":"article","venue":"American Journal of Medical Genetics Part B Neuropsychiatric Genetics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Clozapine; Adrenergic receptor; Serotonin; Internal medicine; Endocrinology; Medicine; Adrenergic; Pharmacology; Receptor; Genetics; Schizophrenia (object-oriented programming); Biology; Psychiatry","score_opus":0.012077335044515993,"score_gpt":0.2944810268887354,"score_spread":0.28240369184421943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2743757905","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784894,0.010680002,0.005324166,0.003659531,0.0015534522,0.0002474445,0.000015877757,0.000011024084,0.000019077472],"genre_scores_gemma":[0.8851607,0.08609584,0.022830054,0.0034243057,0.002192101,0.000008025374,0.000011494585,0.00010375248,0.00017374466],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9953601,0.00085071364,0.0014005943,0.0007010089,0.0010814334,0.00060615333],"domain_scores_gemma":[0.99662805,0.00015711141,0.0006706423,0.0005246003,0.00036525948,0.0016543489],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021275193,0.00042565653,0.00070557045,0.00024379334,0.00014981636,0.000073160496,0.0006641363,0.0002865735,0.0001353411],"category_scores_gemma":[0.000660328,0.00038445657,0.00020905782,0.0006156494,0.00048821795,0.0000061285955,0.00038411462,0.0005228274,0.0000097639195],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0076527046,0.0007548825,0.06145485,0.000025607618,0.0005517898,0.00037827884,0.00024821563,0.000680992,0.5022915,0.000032188684,0.010073934,0.41585502],"study_design_scores_gemma":[0.009073547,0.052977156,0.083575115,0.00018697992,0.00064839073,0.007171304,0.0005183598,0.0014808873,0.051042747,0.00011117473,0.7911165,0.0020978607],"about_ca_topic_score_codex":0.000012579606,"about_ca_topic_score_gemma":0.000009506855,"teacher_disagreement_score":0.7810425,"about_ca_system_score_codex":0.000016262418,"about_ca_system_score_gemma":0.00048400776,"threshold_uncertainty_score":0.99986076},"labels":[],"label_agreement":null},{"id":"W2743762624","doi":"10.1002/bies.201700072","title":"Activation processes in ligand‐activated G protein‐coupled receptors: A case study of the adenosine A<sub>2A</sub> receptor","year":2017,"lang":"en","type":"review","venue":"BioEssays","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Receptor; G protein-coupled receptor; Adenosine; Adenosine receptor; Chemistry; Ligand (biochemistry); Cell biology; Biology; Biochemistry; Agonist","score_opus":0.0554617159934707,"score_gpt":0.3188857681902227,"score_spread":0.26342405219675197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2743762624","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43214762,0.5629901,0.000035152578,0.00001806961,0.00043805162,0.0042667976,0.000040974563,0.0000229521,0.000040227067],"genre_scores_gemma":[0.2962019,0.701688,0.000061370774,0.000009758956,0.00051062886,0.0009619487,0.0002145253,0.00013906401,0.0002128198],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972858,0.00035041015,0.0008713432,0.0008039741,0.00032817535,0.00036028906],"domain_scores_gemma":[0.9972037,0.000042666023,0.0013344334,0.0010518689,0.00028688798,0.0000804507],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005128388,0.00058415195,0.0011741293,0.00016919953,0.00025807455,0.00008374721,0.00070553296,0.0007047289,0.000021579272],"category_scores_gemma":[0.00067522825,0.00039806406,0.00028721686,0.00045578284,0.000087587265,0.000017845447,0.0003035814,0.00041236545,0.0000052490986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010481181,0.0011111449,0.000025959589,0.008393695,0.00038691744,0.00004565574,0.00048578056,0.000004252691,0.812548,0.000005745891,0.0002678565,0.17662017],"study_design_scores_gemma":[0.00094453915,0.00073470356,0.0000012572385,0.009508234,0.0002410527,0.00009528967,0.00054858037,0.0000024543879,0.81395715,0.000007792727,0.17329541,0.00066354417],"about_ca_topic_score_codex":0.0002355793,"about_ca_topic_score_gemma":0.00019854476,"teacher_disagreement_score":0.17595662,"about_ca_system_score_codex":0.000075286924,"about_ca_system_score_gemma":0.000694879,"threshold_uncertainty_score":0.9998471},"labels":[],"label_agreement":null},{"id":"W2745266801","doi":"10.1161/hypertensionaha.113.01772","title":"Natriuretic Peptide Receptor-C Attenuates Hypertension in Spontaneously Hypertensive Rats","year":2014,"lang":"en","type":"article","venue":"Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Medicine; Endocrinology; Receptor; Natriuretic peptide; Heart failure","score_opus":0.011205517493479563,"score_gpt":0.20494417295563164,"score_spread":0.19373865546215208,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2745266801","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99638265,0.00088571565,0.00047412948,0.0005102348,0.0006782868,0.00029421598,0.000004803376,0.00004763993,0.00072230125],"genre_scores_gemma":[0.9933368,0.00040346812,0.0020615996,0.0028678558,0.00047464098,0.000018713405,0.00016973434,0.00007773167,0.0005894843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976992,0.00020968956,0.00043477578,0.0007944142,0.00031517068,0.0005467415],"domain_scores_gemma":[0.99875426,0.00007654236,0.00012149622,0.0005613172,0.0003113723,0.00017503172],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00044304042,0.00036861567,0.00049636763,0.00015266346,0.00015728983,0.00004047267,0.00024654897,0.00037107128,0.00008911251],"category_scores_gemma":[0.00047822215,0.0003202363,0.00017597101,0.00020106761,0.00006904585,0.000011167246,0.00014940943,0.00024397862,0.00018013378],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017071173,0.00008236219,0.00030373476,0.000014569801,0.000018835828,0.00008327718,0.000029713288,0.00016928054,0.98552436,0.000083095285,0.009188831,0.0043312144],"study_design_scores_gemma":[0.0019763336,0.0010792079,0.0012846404,0.00022854416,0.000061427454,0.0015522976,0.00035384216,0.0058023967,0.8716727,0.00035757467,0.11462394,0.0010070911],"about_ca_topic_score_codex":0.000094608906,"about_ca_topic_score_gemma":0.00006086041,"teacher_disagreement_score":0.11385167,"about_ca_system_score_codex":0.00003280032,"about_ca_system_score_gemma":0.00005097897,"threshold_uncertainty_score":0.99992496},"labels":[],"label_agreement":null},{"id":"W2745805188","doi":"10.1038/s41598-017-08996-7","title":"Orphan GPR61, GPR62 and GPR135 receptors and the melatonin MT2 receptor reciprocally modulate their signaling functions","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; McGill University","keywords":"Melatonin; G protein-coupled receptor; Receptor; Melatonin receptor; Cell biology; Signal transduction; Biology; G protein; Biochemistry; Endocrinology","score_opus":0.01025422505729162,"score_gpt":0.22387440387965274,"score_spread":0.21362017882236112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2745805188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98942244,0.0014589401,0.0017676809,0.00047540732,0.005524413,0.00041340862,0.0000061127125,0.000026561505,0.00090503757],"genre_scores_gemma":[0.99064505,0.0001600673,0.0009647361,0.000063347885,0.00028958663,0.000043242835,0.00006997167,0.00003292742,0.0077310535],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977972,0.00011057593,0.000446607,0.0010026247,0.0002804158,0.00036256897],"domain_scores_gemma":[0.9978927,0.000029105677,0.0004801564,0.0012297668,0.00019152323,0.00017678745],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0026894372,0.00024965795,0.00026425358,0.00006255848,0.0022852249,0.0009357574,0.00026308987,0.00018976598,0.00015537614],"category_scores_gemma":[0.00042630202,0.00016696489,0.0001310435,0.00008406444,0.0008975083,0.000032018204,0.00033642814,0.00017202739,0.000007765634],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008511022,0.00002110214,0.0012493692,0.000013352158,0.00008300527,0.000009751551,0.0003302967,0.00005038402,0.9848415,0.00023469965,0.0037110317,0.009370359],"study_design_scores_gemma":[0.0007545989,0.00010827088,0.0002650075,0.00007152144,0.000056773024,0.0002025154,0.00045689574,0.00037372066,0.8445496,0.005166546,0.14757983,0.0004147392],"about_ca_topic_score_codex":0.0000422222,"about_ca_topic_score_gemma":0.000029408504,"teacher_disagreement_score":0.1438688,"about_ca_system_score_codex":0.000013251165,"about_ca_system_score_gemma":0.00009655108,"threshold_uncertainty_score":0.99901366},"labels":[],"label_agreement":null},{"id":"W2747990880","doi":"10.1038/s41598-017-10474-z","title":"Prolonged AT1R activation induces CaV1.2 channel internalization in rat cardiomyocytes","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Fondo Nacional de Desarrollo Científico y Tecnológico; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Instituto Milenio en Inmunología e Inmunoterapia","keywords":"Angiotensin II; Internalization; Cav1.2; Cell biology; Chemistry; Renin–angiotensin system; Contractility; Receptor; Internal medicine; Endocrinology; Voltage-dependent calcium channel; Biology; Calcium; Medicine; Biochemistry","score_opus":0.017875764496769333,"score_gpt":0.26368878079292835,"score_spread":0.245813016296159,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2747990880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927146,0.00009398265,0.002519571,0.000055936544,0.0037716257,0.0002096704,5.69557e-7,0.00000950701,0.00062454643],"genre_scores_gemma":[0.9981743,0.000007614629,0.00010787345,0.000016793883,0.0001829001,0.000028081196,0.000091033115,0.0000118494245,0.0013795187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988323,0.000035316043,0.00024508152,0.0005083198,0.00020036873,0.00017863598],"domain_scores_gemma":[0.9988598,0.000002484783,0.00031104012,0.0006624008,0.0001182169,0.00004603229],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00084754167,0.000101623664,0.00011384269,0.00008043763,0.00033951146,0.00036206338,0.0001694926,0.00010539086,0.000023628316],"category_scores_gemma":[0.0002716055,0.00009358806,0.000058796013,0.00006197673,0.00007988938,0.000024979407,0.00011104717,0.000060604936,0.000002772145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013436775,0.00001783901,0.0037683016,0.000007738296,0.000009675671,0.00002078551,0.00011920498,0.00015577734,0.99395263,0.000016388602,0.00065697974,0.0012612152],"study_design_scores_gemma":[0.00011773534,0.000029936182,0.0010857057,0.00003930591,0.0000039269084,0.000023252716,0.000043227916,0.000101856465,0.98959786,0.00088756095,0.007953532,0.0001160868],"about_ca_topic_score_codex":0.000087574466,"about_ca_topic_score_gemma":0.000072692426,"teacher_disagreement_score":0.007296552,"about_ca_system_score_codex":0.000020710944,"about_ca_system_score_gemma":0.00008878186,"threshold_uncertainty_score":0.38164106},"labels":[],"label_agreement":null},{"id":"W2751149917","doi":"10.1007/978-3-319-60174-8_18","title":"Understanding the Physiological Significance of GPCR Dimers and Oligomers","year":2017,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"G protein-coupled receptor; Context (archaeology); Cooperativity; Receptor; Ligand (biochemistry); Computational biology; Chemistry; Biophysics; Biology; Biochemistry","score_opus":0.08498265553950247,"score_gpt":0.26079414081373675,"score_spread":0.1758114852742343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2751149917","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0063415226,0.0038640273,0.01958938,0.0002559056,0.00056407205,0.00072250015,0.00006364155,0.00002141548,0.96857756],"genre_scores_gemma":[0.85318804,0.0020972318,0.00020761296,0.0001230143,0.00020244643,0.0000053158324,0.000037226553,0.000031745345,0.14410739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992779,0.0000133797885,0.00015906351,0.00030508693,0.00010939127,0.00013518368],"domain_scores_gemma":[0.9993619,0.00001698124,0.0002008256,0.0003455692,0.000029369072,0.000045399083],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001379421,0.000190698,0.00022659067,0.0000180679,0.00014367349,0.000021911916,0.00022086577,0.00028747637,0.00022594816],"category_scores_gemma":[0.000017858563,0.00011941257,0.00012215089,0.000003220314,0.0003187533,0.0000016151811,0.00012267825,0.00012916372,0.0000025676584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049809205,0.0000064899655,0.0000063845673,0.000038506747,0.0002076383,0.0000020959299,0.00003738238,0.000020584126,0.86779314,0.12804382,0.0027102437,0.0010839251],"study_design_scores_gemma":[0.0015333397,0.0021028048,0.00012195949,0.00045290706,0.0004282897,0.000032823922,0.0010719012,0.00018476756,0.5139086,0.16423008,0.31360674,0.0023257637],"about_ca_topic_score_codex":0.000008976366,"about_ca_topic_score_gemma":0.00000598782,"teacher_disagreement_score":0.8468465,"about_ca_system_score_codex":0.000010943298,"about_ca_system_score_gemma":0.000033789573,"threshold_uncertainty_score":0.48695034},"labels":[],"label_agreement":null},{"id":"W2751257819","doi":"10.1016/bs.mcb.2017.07.005","title":"Characterization of GPCR signaling in hypoxia","year":2017,"lang":"en","type":"article","venue":"Methods in cell biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Winnipeg; University of Manitoba; Children's Hospital Research Institute of Manitoba; Research Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Cystic Fibrosis Canada","keywords":"Biology; G protein-coupled receptor; Hypoxia (environmental); Cell biology; Receptor; Signal transduction; Pulmonary hypertension; Internal medicine; Biochemistry; Oxygen; Medicine; Chemistry","score_opus":0.03349120832842354,"score_gpt":0.3575960507909283,"score_spread":0.32410484246250476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2751257819","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93888575,0.0001601825,0.05950376,0.000020888714,0.00028490086,0.00010009499,0.0000054488983,0.0000024048402,0.0010365419],"genre_scores_gemma":[0.9123253,0.00015098574,0.08723463,0.000040308696,0.000079434576,0.000011580865,0.00004641324,0.000010940806,0.00010035678],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892503,0.00031810877,0.00028337678,0.00026343012,0.000028157721,0.00018191096],"domain_scores_gemma":[0.99937433,0.000031047497,0.00021054412,0.0003319108,0.000028679791,0.000023494398],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010646818,0.00009875198,0.00021039139,0.00007380096,0.00004320853,0.000010180922,0.00026517877,0.00023388985,0.000063580694],"category_scores_gemma":[0.00018143996,0.00009417389,0.000049195507,0.000037625527,0.00006454851,0.0000034960524,0.00011426483,0.00008992949,0.0000014133732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030302133,0.00002898817,0.0062038507,0.000012844931,0.000003853037,9.408187e-7,0.000041107876,0.000019932288,0.97791547,0.00011294876,8.3892604e-7,0.015628902],"study_design_scores_gemma":[0.00033745033,0.0001096351,0.0041252044,0.000012790362,0.0000025378158,6.5283183e-7,0.00002037827,0.00014820474,0.99230844,0.00070466055,0.0021284854,0.00010156375],"about_ca_topic_score_codex":0.00005973321,"about_ca_topic_score_gemma":0.00001786979,"teacher_disagreement_score":0.027730871,"about_ca_system_score_codex":0.000007763799,"about_ca_system_score_gemma":0.000026178945,"threshold_uncertainty_score":0.38402998},"labels":[],"label_agreement":null},{"id":"W2754957776","doi":"10.1038/s41598-017-12074-3","title":"Ang-(1-7) is an endogenous β-arrestin-biased agonist of the AT1 receptor with protective action in cardiac hypertrophy","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":106,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Angiotensin II; Agonist; Angiotensin II receptor type 1; Internal medicine; Endocrinology; Cardioprotection; Endogeny; Receptor; Arrestin; Chemistry; Renin–angiotensin system; Pharmacology; G protein-coupled receptor; Biology; Medicine; Blood pressure; Myocardial infarction","score_opus":0.034536342552280594,"score_gpt":0.2545231739219695,"score_spread":0.21998683136968888,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2754957776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99640286,0.00007827871,0.00015373346,0.00003995679,0.0023242133,0.00048682603,0.000010151906,0.0000059981544,0.0004979745],"genre_scores_gemma":[0.9988853,0.0000055625374,0.00048680892,0.000013003345,0.00011153809,0.000042181102,0.000030287096,0.000016113921,0.0004092288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986238,0.00008163071,0.00023172349,0.00058454636,0.00027659556,0.00020171698],"domain_scores_gemma":[0.99799985,0.0000033594465,0.00042528543,0.0013470913,0.00016447016,0.00005994858],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00069639285,0.00012368477,0.0001640061,0.000037286554,0.00057725044,0.00016464868,0.00023609208,0.00009261323,0.00003673493],"category_scores_gemma":[0.000107663596,0.00008401383,0.00010187635,0.00009315101,0.0002688583,0.00001490509,0.00008506965,0.00009025822,0.0000017803137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004571921,0.00004788353,0.005343679,0.000010994175,0.00001611364,0.000008969954,0.00021525015,0.000027447995,0.99197054,0.0000023211269,0.00020347504,0.0021075846],"study_design_scores_gemma":[0.00012706732,0.00013794554,0.0025259617,0.000032425563,0.000012285358,0.00003482679,0.00016051161,0.000014209815,0.9917077,0.00018287355,0.0049452977,0.000118897064],"about_ca_topic_score_codex":0.00031653966,"about_ca_topic_score_gemma":0.00016122223,"teacher_disagreement_score":0.0047418224,"about_ca_system_score_codex":0.00002359152,"about_ca_system_score_gemma":0.00019886266,"threshold_uncertainty_score":0.4439802},"labels":[],"label_agreement":null},{"id":"W2757023848","doi":"10.3389/fphys.2017.00744","title":"Cloning and Functional Characterization of Octβ2-Receptor and Tyr1-Receptor in the Chagas Disease Vector, Rhodnius prolixus","year":2017,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Rhodnius prolixus; Chagas disease; Cloning (programming); Vector (molecular biology); Receptor; Molecular cloning; Biology; Computational biology; Immunology; Recombinant DNA; Peptide sequence; Biochemistry; Computer science; Gene; Ecology; Insect","score_opus":0.008512439242226524,"score_gpt":0.21896270190078096,"score_spread":0.21045026265855443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2757023848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99749184,0.0003920137,0.0010484069,0.00016744588,0.0006446758,0.00019887736,0.000029237257,0.0000026689643,0.000024857922],"genre_scores_gemma":[0.998435,0.00040877901,0.0005084648,0.00010081776,0.00022828764,0.000041118903,0.00021092876,0.000011208115,0.00005539102],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9992027,0.00009833741,0.00017011884,0.0002901466,0.00006663222,0.0001720347],"domain_scores_gemma":[0.9995378,0.000009355424,0.00014099928,0.0002428836,0.000026483269,0.000042427764],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018821163,0.00011922077,0.00018307229,0.000049191156,0.000114949,0.00002261707,0.00014355319,0.00010673548,0.00002079431],"category_scores_gemma":[0.00007688653,0.0000959168,0.000031583964,0.000030150257,0.0001620758,0.000013232917,0.00008946409,0.00009312098,6.8570625e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028737372,0.00003956,0.024599895,0.000027517257,0.000016298325,5.5698183e-7,0.00012723476,0.0000070588094,0.972899,0.0002942469,0.00022576549,0.0014754704],"study_design_scores_gemma":[0.0012277649,0.00026821907,0.85410446,0.0000535045,0.000016573244,0.0000026745577,0.00020783229,0.00063874264,0.13882536,0.0007879121,0.0036118357,0.0002551446],"about_ca_topic_score_codex":0.000017419226,"about_ca_topic_score_gemma":0.000004585867,"teacher_disagreement_score":0.83407366,"about_ca_system_score_codex":0.000007990265,"about_ca_system_score_gemma":0.000032480788,"threshold_uncertainty_score":0.39113736},"labels":[],"label_agreement":null},{"id":"W2759588691","doi":"10.1161/res.113.suppl_1.a318","title":"Abstract 318: Dynamic Mass Redistribution Analysis Of Endogenous β-adrenergic Receptor Signaling In Cardiac Cells","year":2013,"lang":"en","type":"article","venue":"Circulation Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Stimulation; Endogeny; Endocrinology; Receptor; Internal medicine; Agonist; Cholera toxin; Chemistry; Propranolol; Signal transduction; Adrenergic receptor; Biology; Cell biology; Medicine","score_opus":0.03653471968610693,"score_gpt":0.30340514161210674,"score_spread":0.2668704219259998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2759588691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99485135,0.0004569485,0.0037076822,0.00002716308,0.00010086788,0.00033417504,0.000051565406,0.0000072116763,0.00046301124],"genre_scores_gemma":[0.9984985,0.00009144252,0.00028341415,0.0000049113296,0.00006297497,0.000053884134,0.00093987345,0.000016223126,0.00004879941],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99819976,0.00023341032,0.0003980539,0.0003763199,0.00043409938,0.00035836254],"domain_scores_gemma":[0.9990024,0.000051304054,0.00010764731,0.00032151252,0.0004293141,0.00008782082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012539736,0.000115049894,0.00026128977,0.00042706766,0.00009085662,0.000047658414,0.00017430531,0.00020447708,0.000704301],"category_scores_gemma":[0.00009351764,0.00012029752,0.00019831053,0.00095820497,0.00005907676,0.000011786317,0.0000451794,0.00017499604,0.000028394586],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014751106,0.000034484307,0.0028809437,0.000021053467,0.00015893634,8.025199e-7,0.00004986659,0.0348707,0.9609465,0.00006192165,0.000046997444,0.00091302575],"study_design_scores_gemma":[0.00020070511,0.00005536165,0.015850158,0.000018276245,0.00004179002,2.515686e-7,0.00029182073,0.013745905,0.9693237,0.00023219093,0.00008830636,0.00015155645],"about_ca_topic_score_codex":0.0003609553,"about_ca_topic_score_gemma":0.000018515286,"teacher_disagreement_score":0.021124793,"about_ca_system_score_codex":0.00009315798,"about_ca_system_score_gemma":0.00009074635,"threshold_uncertainty_score":0.77116024},"labels":[],"label_agreement":null},{"id":"W2761940121","doi":"10.1038/nnano.2017.188","title":"A synthetic intrabody-based selective and generic inhibitor of GPCR endocytosis","year":2017,"lang":"en","type":"article","venue":"Nature Nanotechnology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Wellcome Trust","keywords":"G protein-coupled receptor; Endocytosis; Clathrin; Internalization; Allosteric regulation; Cell biology; Scaffold protein; Chemistry; Biology; Receptor; Signal transduction; Biochemistry","score_opus":0.00531468419248805,"score_gpt":0.23619400338018798,"score_spread":0.23087931918769994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2761940121","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945923,0.002483409,0.0018026108,0.00051525986,0.000239365,0.00016177238,0.000016896718,0.0000252117,0.00016316256],"genre_scores_gemma":[0.99591684,0.00018132196,0.0035899384,0.00013183345,0.00010113016,0.000021231122,0.000010032572,0.000020635074,0.000027047266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991079,0.000029356721,0.00015901873,0.00038880052,0.00009405506,0.00022085676],"domain_scores_gemma":[0.9991019,0.000014850973,0.00019421859,0.00054332317,0.00010619541,0.000039546503],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012332364,0.00015606146,0.00023157866,0.00009643151,0.00016971424,0.000019600935,0.00032259052,0.0010534157,0.000014658517],"category_scores_gemma":[0.00038427624,0.00014111867,0.000069940244,0.0000614185,0.00024070324,0.0000036136144,0.00014529823,0.00034608194,0.0000012569218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006719158,0.000029982577,0.0003130479,0.000017284794,0.00003620055,0.000003452389,0.000008485123,0.000006234,0.9870099,0.00092472695,0.00013184756,0.011451679],"study_design_scores_gemma":[0.00052922557,0.00038885113,0.00016336306,0.000021756741,0.00002322723,0.000020481686,0.00001523262,0.00009485987,0.9934817,0.0011112447,0.004002488,0.00014756803],"about_ca_topic_score_codex":0.000014566079,"about_ca_topic_score_gemma":0.000021754644,"teacher_disagreement_score":0.011304111,"about_ca_system_score_codex":0.000011751083,"about_ca_system_score_gemma":0.00007375837,"threshold_uncertainty_score":0.81249064},"labels":[],"label_agreement":null},{"id":"W2763861623","doi":"10.1093/eurheartj/ehx504.p3999","title":"P3999Excessive activation of beta-2 adrenergic receptors induces arrhythmic calcium oscillations and ryanodine receptor phosphorylation at ser2809 but not at ser2815","year":2017,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; Simon Fraser University","funders":"","keywords":"Ryanodine receptor; Medicine; Adrenergic receptor; Ryanodine receptor 2; Phosphorylation; Receptor; Calcium; BETA (programming language); Internal medicine; Endocrinology; Cell biology; Biology","score_opus":0.040926071634219026,"score_gpt":0.2825722818569917,"score_spread":0.24164621022277266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2763861623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967472,0.00034654763,0.00043071748,0.00046546187,0.0006090319,0.00012509905,0.000019855383,0.0000092759665,0.0012468272],"genre_scores_gemma":[0.99454343,0.00033553567,0.000966427,0.00009627881,0.0009118119,0.0000023321227,0.000067555426,0.00004325194,0.0030333512],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861544,0.00022087144,0.00037732345,0.00031863953,0.00023131097,0.00023638649],"domain_scores_gemma":[0.9987072,0.000023471996,0.0006052833,0.000336859,0.00015516896,0.00017202678],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004957712,0.00019888511,0.00022143435,0.00007484744,0.0010453808,0.00011369384,0.00018573985,0.00010900459,0.00036258885],"category_scores_gemma":[0.00014037357,0.00018045699,0.00012310149,0.000042342046,0.00011787204,0.000038094695,0.00024738992,0.00018394506,0.000024348868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016251433,0.000015190536,0.004292144,0.000009998085,0.000049156915,0.0000026620066,0.00013622547,0.00018582187,0.99184996,0.000015216135,0.0019895132,0.0012915917],"study_design_scores_gemma":[0.00058012555,0.00022587736,0.020436352,0.00007009852,0.000025009489,0.00012332789,0.00006500099,0.000072197654,0.95569354,0.0000133924395,0.02249078,0.0002042942],"about_ca_topic_score_codex":0.0000111370855,"about_ca_topic_score_gemma":0.0000055298788,"teacher_disagreement_score":0.036156423,"about_ca_system_score_codex":0.000044137418,"about_ca_system_score_gemma":0.000052892778,"threshold_uncertainty_score":0.804033},"labels":[],"label_agreement":null},{"id":"W2767214604","doi":"10.1007/s00429-017-1547-3","title":"Mapping GPR88-Venus illuminates a novel role for GPR88 in sensory processing","year":2017,"lang":"en","type":"article","venue":"Brain Structure and Function","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; McGill University; Douglas Mental Health University Institute","funders":"National Institute on Drug Abuse; National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; Québec Consortium for Drug Discovery; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Neuroscience; Somatosensory system; Sensory system; Sensory processing; Psychology; Biology","score_opus":0.012051426317444304,"score_gpt":0.2386407568797969,"score_spread":0.22658933056235261,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2767214604","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762973,0.00065447635,0.022274898,0.00016074824,0.00023519155,0.00018344884,0.00002138302,0.000007664132,0.00016487784],"genre_scores_gemma":[0.9971344,0.000013637462,0.0018218246,0.00019451107,0.00040142075,0.000013416208,0.00005355557,0.000015473595,0.00035176566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993924,0.000009931186,0.00011522349,0.00026865653,0.00005314606,0.0001606719],"domain_scores_gemma":[0.99965835,0.000008500388,0.000100928424,0.00015509162,0.00004354657,0.000033588774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012188583,0.0001108411,0.00010720157,0.000039063296,0.00027910343,0.00008447122,0.00007157832,0.00015628179,0.0000093138915],"category_scores_gemma":[0.000093478906,0.00010177134,0.00003698006,0.000020488687,0.000037823578,0.000011913963,0.00003902249,0.00006531375,2.2818462e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007427175,0.000006123077,0.0006391528,0.000038034876,0.00001011582,4.103982e-7,0.00015102726,0.000027574855,0.92609096,0.00008014568,0.00007891857,0.07280328],"study_design_scores_gemma":[0.0032381853,0.0005424267,0.037151705,0.00015768406,0.00003438279,0.00006180069,0.0019817897,0.0047949115,0.84392774,0.007060283,0.10035422,0.00069485756],"about_ca_topic_score_codex":0.000018930448,"about_ca_topic_score_gemma":0.00003977672,"teacher_disagreement_score":0.1002753,"about_ca_system_score_codex":0.0000066465914,"about_ca_system_score_gemma":0.0000232748,"threshold_uncertainty_score":0.41501147},"labels":[],"label_agreement":null},{"id":"W2769024665","doi":"10.1038/s41598-017-16332-2","title":"The directed evolution of ligand specificity in a GPCR and the unequal contributions of efficacy and affinity","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"G protein-coupled receptor; Ligand (biochemistry); Kluyveromyces lactis; Biology; Saccharomyces cerevisiae; Receptor; Pheromone; Sex pheromone; Mutation; Yeast; Genetics; Computational biology; Gene","score_opus":0.009057580564621501,"score_gpt":0.252044033517876,"score_spread":0.24298645295325452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769024665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99755317,0.0012155334,0.00022022665,0.00008904133,0.00055275386,0.00018944363,0.000006111402,0.0000022024772,0.0001715035],"genre_scores_gemma":[0.99970585,0.000085586704,0.000041035928,0.0000010361873,0.000025429345,0.000004514273,0.0000067375145,0.000002559454,0.00012724278],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99922127,0.0000662431,0.00026569038,0.00022250152,0.00011895199,0.000105373394],"domain_scores_gemma":[0.99896693,0.00004581673,0.0003326422,0.00048916246,0.0001385211,0.000026936024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001968693,0.000055615303,0.00011932252,0.000019865776,0.0005004333,0.00008987451,0.00009578744,0.000051507457,0.0000021390688],"category_scores_gemma":[0.0010277074,0.000032482596,0.00003389483,0.000050348957,0.0008140815,0.000004684555,0.000109604865,0.00004807783,7.485863e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088734705,0.000029098257,0.003773721,0.0000062120607,0.000013578935,0.0000022706197,0.00010171768,0.00001162705,0.9935382,0.0014640004,0.00011209621,0.0008587357],"study_design_scores_gemma":[0.00074880343,0.00004053064,0.03786855,0.00002787246,0.000015729087,0.000015016237,0.00012414917,0.00020010839,0.95354193,0.005490615,0.0018624307,0.00006424451],"about_ca_topic_score_codex":0.00013289653,"about_ca_topic_score_gemma":0.0001466116,"teacher_disagreement_score":0.039996255,"about_ca_system_score_codex":0.0000062284876,"about_ca_system_score_gemma":0.00005494245,"threshold_uncertainty_score":0.3848979},"labels":[],"label_agreement":null},{"id":"W2769686732","doi":"10.1074/jbc.m117.814947","title":"Ligand-specific conformational transitions and intracellular transport are required for atypical chemokine receptor 3–mediated chemokine scavenging","year":2017,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; CHU Sainte-Justine Foundation","keywords":"Chemokine receptor; C-C chemokine receptor type 6; CXCL11; CCL21; XCL2; G protein-coupled receptor; Internalization; Chemokine; Chemotaxis; Cell biology; CCL25; CCR1; Chemistry; Ligand (biochemistry); Arrestin; Receptor; Biology; Signal transduction; Biochemistry","score_opus":0.023468918839945774,"score_gpt":0.24282148146459293,"score_spread":0.21935256262464714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2769686732","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98777527,0.0008403987,0.010127585,0.0007817911,0.00013755345,0.00012294241,0.00010900252,0.000007957204,0.000097496595],"genre_scores_gemma":[0.99525946,0.0007513323,0.0026716609,0.00007561605,0.0008721274,0.000009026983,0.0002741835,0.000014562528,0.00007205621],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988455,0.0000135135915,0.00052079716,0.00023110173,0.0001495409,0.00023953943],"domain_scores_gemma":[0.998814,0.000031191325,0.00053113705,0.00020208304,0.00024040116,0.00018117574],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043428756,0.00019263751,0.00034540897,0.000020085914,0.00026706682,0.000054309472,0.00028275134,0.00037658698,0.000146114],"category_scores_gemma":[0.00022721937,0.00015088676,0.00022733258,0.000026319061,0.0001822971,0.000019158579,0.000033027733,0.00021555593,0.0000011207532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059123395,0.00006861323,0.00044019165,0.00004534376,0.00006548874,0.000008600161,0.000021712189,0.000010723949,0.9977192,0.000027910599,0.0003005168,0.0007004567],"study_design_scores_gemma":[0.0016121458,0.00022237067,0.0013986833,0.00008171814,0.00002169966,0.0001415699,0.000115972754,0.00007809178,0.9767103,0.00013759959,0.019271852,0.00020797156],"about_ca_topic_score_codex":2.5565654e-7,"about_ca_topic_score_gemma":1.5402328e-7,"teacher_disagreement_score":0.021008885,"about_ca_system_score_codex":0.00001868703,"about_ca_system_score_gemma":0.000045894714,"threshold_uncertainty_score":0.61529833},"labels":[],"label_agreement":null},{"id":"W2770983838","doi":"10.1007/978-1-4939-7386-6_19","title":"High-Efficiency Expression of Yeast-Derived G-Protein Coupled Receptors and 19F Labeling for Dynamical Studies","year":2017,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Process Research Ortech (Canada); Canada Research Chairs; University of Toronto","funders":"","keywords":"Yeast; Protein expression; Cell biology; Receptor; Biology; Chemistry; Computational biology; Biochemistry; Gene","score_opus":0.030695731710328845,"score_gpt":0.3891719458508525,"score_spread":0.35847621414052366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770983838","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5179642,0.0014074704,0.48014617,0.00003965691,0.00020303387,0.00022393012,0.0000062436484,0.0000037852408,0.000005493634],"genre_scores_gemma":[0.40476274,0.00018664903,0.5948489,0.00002751753,0.000041768144,0.00006558954,0.000020833459,0.000017957107,0.00002803087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99852675,0.00034227155,0.00033727472,0.00046830397,0.00005659883,0.00026881738],"domain_scores_gemma":[0.9991149,0.000056950983,0.00024540225,0.0004214551,0.00011236593,0.000048935883],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011615591,0.00018134063,0.00039863406,0.000064640924,0.00014792552,0.000015131247,0.00028517997,0.00027540175,0.000008631601],"category_scores_gemma":[0.00162465,0.00015634976,0.000089106754,0.000034047647,0.00026942472,0.0000035005073,0.0002965697,0.00009772853,2.1371251e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009969595,0.000030088902,0.00012342689,0.000040782084,0.000035300112,0.0000011822804,0.00005245796,0.000048806975,0.9928525,0.0011114412,0.0000030325398,0.0056012683],"study_design_scores_gemma":[0.00083124056,0.00042304918,0.000037627895,0.00006167487,0.000014717077,0.0000017851401,0.00010923391,0.00077039603,0.99280506,0.004587613,0.0001828251,0.00017477802],"about_ca_topic_score_codex":0.000032461016,"about_ca_topic_score_gemma":0.000008395709,"teacher_disagreement_score":0.11470272,"about_ca_system_score_codex":0.000011734529,"about_ca_system_score_gemma":0.000029557945,"threshold_uncertainty_score":0.6375758},"labels":[],"label_agreement":null},{"id":"W2771868228","doi":"10.1038/s41467-017-02257-x","title":"Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity","year":2017,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of Allergy and Infectious Diseases; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; Heart and Stroke Foundation of Canada","keywords":"Allosteric regulation; Functional selectivity; In silico; Signal transduction; Computational biology; Biology; Mutagenesis; Effector; Phenotype; Cell biology; Receptor; Genetics; Chemistry; G protein-coupled receptor; Mutation; Gene","score_opus":0.023326163266910078,"score_gpt":0.29091445722719483,"score_spread":0.2675882939602848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2771868228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99349976,0.003465288,0.00078871346,0.0013408503,0.00029362759,0.0001449173,0.000024621764,0.000005863725,0.00043636424],"genre_scores_gemma":[0.9980685,0.00027717164,0.001348091,0.000078426434,0.00008192483,0.0000104579585,0.000041796044,0.000006228991,0.00008738985],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99955744,0.000072480805,0.00009582991,0.00011812881,0.000084952066,0.00007115458],"domain_scores_gemma":[0.9987628,0.00002811759,0.00014937599,0.00090199703,0.00013709391,0.000020641897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000117231124,0.00006616389,0.00007375201,0.000014139143,0.0008015638,0.00002612644,0.0004175759,0.00016545365,0.0000122629],"category_scores_gemma":[0.00014618873,0.00005039246,0.00005332636,0.000028934697,0.00011464099,0.000009955989,0.00030261851,0.00025053587,3.3639293e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003617845,0.000016879272,0.016715955,0.0000051322068,0.0000525637,2.2239911e-8,0.000017196355,0.00004518778,0.97922695,0.0014583155,0.00038987308,0.002035766],"study_design_scores_gemma":[0.0008054129,0.00008467042,0.6900115,0.000027685262,0.00007638329,0.000029322098,0.00009712665,0.005552377,0.2847554,0.0013951189,0.01694347,0.0002215063],"about_ca_topic_score_codex":0.000028256381,"about_ca_topic_score_gemma":0.0001783599,"teacher_disagreement_score":0.69447154,"about_ca_system_score_codex":0.0000117583595,"about_ca_system_score_gemma":0.000043502172,"threshold_uncertainty_score":0.61650616},"labels":[],"label_agreement":null},{"id":"W2776242589","doi":"10.1007/s00018-017-2732-5","title":"Delta opioid receptors recycle to the membrane after sorting to the degradation path","year":2017,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"ESCRT; Endosome; Endocytic cycle; G protein-coupled receptor; Receptor; Internalization; Cell biology; Sorting; δ-opioid receptor; Agonist; Chemistry; Biology; Biochemistry; Endocytosis; Computer science","score_opus":0.013242706319041111,"score_gpt":0.24827458787786863,"score_spread":0.2350318815588275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2776242589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9619735,0.001596278,0.031474873,0.003624691,0.0005300583,0.00033118125,0.000005007457,0.0000074734544,0.00045696006],"genre_scores_gemma":[0.9948238,0.0001339887,0.00207891,0.0023073794,0.00023732385,0.000050100018,0.000010431614,0.000013308711,0.0003447191],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987278,0.00008437927,0.00017808811,0.000449014,0.00026628643,0.0002944267],"domain_scores_gemma":[0.99913335,0.0000104964065,0.00009765872,0.00053217314,0.000057272024,0.0001690349],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010030094,0.00014565115,0.00010729614,0.000030787192,0.0011721321,0.00031227464,0.00067357527,0.000067616595,0.000035850928],"category_scores_gemma":[0.00038700423,0.00008594308,0.000074274525,0.0000949898,0.00014432639,0.000013027793,0.00032289265,0.00007407827,0.00001550224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021615768,0.000008949142,0.00036221792,0.0000057056955,0.00001386963,0.0000027762246,0.00026257816,0.00027131458,0.9908564,0.00022715918,0.0008061523,0.007161263],"study_design_scores_gemma":[0.00010524659,0.00017789085,0.00022202986,0.000024075785,0.00001765572,0.0000034420589,0.0004163413,0.00036397882,0.9225036,0.00010985711,0.0758605,0.00019539375],"about_ca_topic_score_codex":0.00008318892,"about_ca_topic_score_gemma":0.000057491838,"teacher_disagreement_score":0.07505435,"about_ca_system_score_codex":0.0000048230845,"about_ca_system_score_gemma":0.00006667906,"threshold_uncertainty_score":0.901521},"labels":[],"label_agreement":null},{"id":"W2776847378","doi":"10.1055/s-0037-1612591","title":"Three Mutations in the Bilateral Frontoparietal Polymicrogyria Gene GPR56 in Pakistani Intellectual Disability Families","year":2017,"lang":"en","type":"article","venue":"Journal of Pediatric Genetics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; University of Toronto; Centre for Addiction and Mental Health","funders":"Canadian Institutes of Health Research; Peterborough K. M. Hunter Charitable Foundation","keywords":"Polymicrogyria; Frameshift mutation; Genetics; Exome sequencing; Intellectual disability; Biology; Mutation; Haploinsufficiency; Phenotype; Epilepsy; Gene; Neuroscience","score_opus":0.019071897379985204,"score_gpt":0.27618723180183846,"score_spread":0.25711533442185325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2776847378","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946703,0.0018695889,0.0027670108,0.00015168077,0.00035220745,0.00011926701,0.000011072608,0.0000011430783,0.000057743317],"genre_scores_gemma":[0.99537003,0.0011326692,0.0023959987,0.000043403306,0.0010257461,0.0000033154236,0.000007742484,0.000012238277,0.000008827961],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9987981,0.00008243386,0.00052756356,0.000168667,0.0002015705,0.00022166972],"domain_scores_gemma":[0.99913096,0.000050171915,0.00032205725,0.00035862974,0.000085517895,0.000052681775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006486491,0.00013837268,0.00019239738,0.00006613368,0.0001351983,0.000107850836,0.00056753703,0.00013213562,0.00003009906],"category_scores_gemma":[0.00028431052,0.00010087734,0.0001317225,0.000073092335,0.00010558262,0.000009890524,0.00009925562,0.00022761645,0.0000020004456],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027431888,0.0005749511,0.6655604,0.000029017756,0.00006389846,0.0000659604,0.0031043252,0.0009869561,0.32348877,0.000055456847,0.00062630273,0.005169632],"study_design_scores_gemma":[0.0044314754,0.0018037248,0.8610854,0.000020224346,0.00023237313,0.00024343142,0.0053629624,0.000815828,0.11960516,0.0036074303,0.0020574017,0.000734598],"about_ca_topic_score_codex":0.00011416489,"about_ca_topic_score_gemma":0.0008433402,"teacher_disagreement_score":0.20388362,"about_ca_system_score_codex":0.000030896215,"about_ca_system_score_gemma":0.00012446412,"threshold_uncertainty_score":0.41136584},"labels":[],"label_agreement":null},{"id":"W2780371039","doi":"10.1165/rcmb.2017-0333ed","title":"Regulators of G-Protein Signaling as Asthma Therapy?","year":2017,"lang":"en","type":"editorial","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Asthma; Signal transduction; Computational biology; Medicine; Bioinformatics; Biology; Cell biology; Immunology","score_opus":0.005764788899303695,"score_gpt":0.26053991664621456,"score_spread":0.25477512774691086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2780371039","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9069974,0.026285775,0.002993967,0.000021809119,0.06315909,0.00021152325,0.00003964289,0.0000048866614,0.0002859047],"genre_scores_gemma":[0.86319506,0.003018602,0.0024796883,0.00027938175,0.13050108,0.000013642712,0.00008730109,0.00016595374,0.00025928504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99742067,0.0005493402,0.00085151475,0.00048523053,0.00034214102,0.00035112497],"domain_scores_gemma":[0.99584544,0.00005849223,0.0027783934,0.00055688614,0.00058713247,0.00017363022],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001148214,0.0004259712,0.0010161656,0.00020593245,0.000120518955,0.000038455397,0.00067096663,0.0006978106,0.000029320481],"category_scores_gemma":[0.00038218647,0.00035846798,0.0004351135,0.00007079459,0.0006611165,0.000006550118,0.00016361462,0.0005325286,0.0000014386129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003492102,0.00004488292,0.000028331326,0.00003341101,0.00023882605,0.000033555873,0.000026605594,0.000008813377,0.96483016,0.000032143045,0.007613305,0.026760766],"study_design_scores_gemma":[0.00055417774,0.004790691,0.000001717272,0.0000720541,0.00002925651,0.00000906329,0.000057336627,2.5056195e-7,0.52854633,0.00016737817,0.46554363,0.00022808327],"about_ca_topic_score_codex":0.00004115932,"about_ca_topic_score_gemma":0.000001317387,"teacher_disagreement_score":0.45793033,"about_ca_system_score_codex":0.000016200856,"about_ca_system_score_gemma":0.00073679804,"threshold_uncertainty_score":0.99988675},"labels":[],"label_agreement":null},{"id":"W2781602382","doi":"10.3389/fncir.2017.00107","title":"Opposing Cholinergic and Serotonergic Modulation of Layer 6 in Prefrontal Cortex","year":2018,"lang":"en","type":"article","venue":"Frontiers in Neural Circuits","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Alzheimer Society Research Program; Canada Foundation for Innovation; Canadian Institutes of Health Research; Alzheimer Society; Children’s Hospital of Wisconsin Research Institute; Seattle Children's Research Institute; University of Washington","keywords":"Neuroscience; Prefrontal cortex; Serotonergic; Optogenetics; Acetylcholine; Cholinergic; Pyramidal cell; Neuromodulation; Biology; Chemistry; Serotonin; Central nervous system; Endocrinology; Hippocampus","score_opus":0.013513293023808062,"score_gpt":0.24480553739704525,"score_spread":0.2312922443732372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2781602382","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99608314,0.0006704807,0.002410824,0.000011138685,0.0003925395,0.00016866629,0.000003935996,0.0000040747746,0.00025520878],"genre_scores_gemma":[0.9990818,0.000053088337,0.00058367406,0.00004929142,0.00011628943,0.000008172718,0.000022013715,0.000013591211,0.00007211377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923545,0.000044632685,0.00021432716,0.00025251883,0.000083728155,0.0001693279],"domain_scores_gemma":[0.9997389,0.0000025803527,0.00006678579,0.000120787416,0.00003211814,0.000038872386],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119451324,0.00010170786,0.00015317189,0.00008683069,0.000025583682,0.0000099236895,0.00008104567,0.00011185781,0.000011613893],"category_scores_gemma":[0.000015846561,0.00010296553,0.000029114986,0.0000858712,0.00005836367,0.000009934794,0.000038150734,0.0000685347,4.0982698e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034736713,0.000020811265,0.040520687,0.000013305769,0.000006409691,0.0000020791322,0.00012181091,0.0004412498,0.95104426,0.000017230062,0.00007095453,0.0077064447],"study_design_scores_gemma":[0.0020464926,0.0005795931,0.31494302,0.00007830008,0.000011970245,0.000020830335,0.00024978438,0.066108555,0.61467516,0.00054421934,0.00035549005,0.00038659916],"about_ca_topic_score_codex":0.000029097084,"about_ca_topic_score_gemma":0.000033066703,"teacher_disagreement_score":0.33636913,"about_ca_system_score_codex":0.000014558824,"about_ca_system_score_gemma":0.000015703685,"threshold_uncertainty_score":0.41988125},"labels":[],"label_agreement":null},{"id":"W2782378357","doi":"10.1038/nature25153","title":"Structure of the glucagon receptor in complex with a glucagon analogue","year":2018,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":143,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Peptide; Chemistry; Glucagon receptor; Transmembrane domain; Receptor; Ligand (biochemistry); Protein structure; Biophysics; Biochemistry; Biology; Glucagon; Hormone","score_opus":0.005862114234981169,"score_gpt":0.2356406967603488,"score_spread":0.22977858252536762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2782378357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.998698,0.0003094729,0.0001127809,0.00017668637,0.00019676292,0.000132944,0.00004565248,0.000003899699,0.00032382403],"genre_scores_gemma":[0.9976593,0.000012475065,0.0013210782,0.0005166236,0.0002831289,0.0000016390281,0.0000884728,0.000013994352,0.00010328209],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932736,0.00004704755,0.00011796698,0.00021662319,0.00013920887,0.00015179918],"domain_scores_gemma":[0.9995025,0.0000042966017,0.00007884703,0.00028055566,0.00010534419,0.000028473396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006530341,0.00011283794,0.000119203294,0.000027832124,0.000048988837,0.000008603468,0.00023714743,0.0006474678,0.00019863446],"category_scores_gemma":[0.000032427193,0.00006748786,0.000048460686,0.00018589589,0.00008715129,0.0000021847347,0.000061181745,0.0004729058,0.0000013139775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107864034,0.000015026223,0.0016811779,0.000009366818,0.000017764924,2.9968228e-7,0.000074251955,0.000014639011,0.99566597,0.00025607596,0.0016891194,0.00046843482],"study_design_scores_gemma":[0.00036335,0.00025043008,0.0050968667,0.000026508496,0.0000064655706,0.0000052687697,0.00007608185,0.000023133256,0.9702712,0.0001274349,0.023654072,0.00009918382],"about_ca_topic_score_codex":0.000023366827,"about_ca_topic_score_gemma":0.00046734198,"teacher_disagreement_score":0.025394775,"about_ca_system_score_codex":0.0000103645525,"about_ca_system_score_gemma":0.000050184877,"threshold_uncertainty_score":0.4993865},"labels":[],"label_agreement":null},{"id":"W2783042853","doi":"10.7287/peerj.preprints.4043v1","title":"Phylogenetic evidence suggests a later origin of the DRD <sub>2l</sub> and DRD <sub>4rs</sub> dopamine receptor gene lineages","year":2018,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Dopamine receptor; Biology; Dopamine; Phylogenetic tree; Monophyly; Dopaminergic; Receptor; Sister group; Clade; Genetics; Neuroscience; Gene","score_opus":0.018907584923923457,"score_gpt":0.25447317333088537,"score_spread":0.2355655884069619,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2783042853","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898315,0.0061617433,0.0015652643,0.00021197692,0.0011775264,0.0008269146,0.00010109467,0.00003418487,0.000089802576],"genre_scores_gemma":[0.9831222,0.012194116,0.0024584737,0.0002550424,0.0012500236,0.000078076024,0.00015484195,0.00010685494,0.0003803273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99647176,0.00028353045,0.0008171191,0.0013703434,0.00045762435,0.0005996431],"domain_scores_gemma":[0.99733007,0.00007285172,0.000547132,0.0013983758,0.00043745327,0.00021412667],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00060506206,0.00072600646,0.0007012369,0.000108131484,0.00016458884,0.0001174954,0.00087911676,0.00094773195,0.00014782918],"category_scores_gemma":[0.00023329655,0.0005342491,0.0003877335,0.00016065477,0.000363249,0.000008973212,0.0017672583,0.00047458833,0.00002740191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010344959,0.000065813845,0.0019376598,0.000235711,0.00018273378,0.000002984694,0.0000649441,0.00011718847,0.99185723,0.000011916769,0.0014761435,0.0039442237],"study_design_scores_gemma":[0.00040533853,0.00040675577,0.0011191791,0.00045856,0.00013480861,0.00002284087,0.000022792326,0.0001726476,0.9946989,0.00017736587,0.0017462593,0.0006345487],"about_ca_topic_score_codex":0.00004837869,"about_ca_topic_score_gemma":0.00008485364,"teacher_disagreement_score":0.006709248,"about_ca_system_score_codex":0.000040777682,"about_ca_system_score_gemma":0.00027629378,"threshold_uncertainty_score":0.9997109},"labels":[],"label_agreement":null},{"id":"W2783365818","doi":"10.1007/s11010-018-3273-4","title":"Study of adenylyl cyclase-GαS interactions and identification of novel AC ligands","year":2018,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba; Research Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; University of Manitoba; Research Manitoba","keywords":"Adenylyl cyclase; S-Nitrosylation; Gene isoform; Biochemistry; Cell biology; Mutagenesis; Chemistry; Docking (animal); Nitric oxide; Nitrosylation; Enzyme; Biology; Cysteine; Gene; Mutation","score_opus":0.00934632606639808,"score_gpt":0.25059552864386164,"score_spread":0.24124920257746357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2783365818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894807,0.0005844101,0.009537682,0.000015737565,0.00006774075,0.0001305969,0.000017401073,0.000005136244,0.00016060412],"genre_scores_gemma":[0.99938226,0.0000145480635,0.00027022918,0.000018852423,0.000079548845,0.0000099680365,0.00005715636,0.000017256165,0.00015017514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990607,0.0000173293,0.00031585328,0.00034016016,0.00012909941,0.00013686375],"domain_scores_gemma":[0.9992992,0.000005754071,0.00016750129,0.0003147897,0.00013692546,0.00007577403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015885443,0.00013982898,0.00016120599,0.000038094226,0.00006197106,0.000018465224,0.00011019128,0.000112818256,0.000014002901],"category_scores_gemma":[0.000042181324,0.0001430247,0.00005578447,0.00008204397,0.00012548969,0.0000040375744,0.00011533919,0.00006472806,3.9873328e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003836294,0.00026213657,0.00041312785,0.000047310048,0.00007788797,0.0000018607212,0.00012327626,0.0000028734676,0.9986855,0.00004138092,0.000021140817,0.0002851399],"study_design_scores_gemma":[0.0006257604,0.00033867738,0.00006701662,0.000022224618,0.00005423464,0.00001553552,0.001059996,0.00007689,0.997499,0.000023793702,0.00008000757,0.00013686338],"about_ca_topic_score_codex":0.000015675381,"about_ca_topic_score_gemma":0.000002486554,"teacher_disagreement_score":0.009901574,"about_ca_system_score_codex":0.00000464466,"about_ca_system_score_gemma":0.000023998804,"threshold_uncertainty_score":0.5832378},"labels":[],"label_agreement":null},{"id":"W2784317232","doi":"10.1016/j.cellsig.2018.01.002","title":"Receptor- and cellular compartment-specific activation of the cAMP/PKA pathway by α1-adrenergic and ETA endothelin receptors","year":2018,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"G protein-coupled receptor; Receptor; Cell biology; Agonist; Signal transduction; Biology; Gs alpha subunit; G protein; HEK 293 cells; Gq alpha subunit; Phenylephrine; Adrenergic receptor; Chemistry; Endocrinology; Biochemistry","score_opus":0.010868265384950204,"score_gpt":0.1981449159497947,"score_spread":0.1872766505648445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2784317232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9677721,0.0044127465,0.026885577,0.0000434987,0.00035989404,0.0002550942,0.000020959747,0.000012938931,0.00023717791],"genre_scores_gemma":[0.9972791,0.0004976942,0.0010350985,0.00006873593,0.00037075707,0.000011451821,0.00012339326,0.000040568673,0.00057320006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985259,0.00015374947,0.00034903153,0.00048159852,0.00021586394,0.00027382118],"domain_scores_gemma":[0.9992282,0.000029162191,0.00022252764,0.00030750688,0.00011228838,0.00010032916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038601592,0.00024208927,0.00023552788,0.00004194647,0.00024889928,0.00004890694,0.00021057835,0.00019483897,0.00023229903],"category_scores_gemma":[0.000022477927,0.00019477424,0.000092370254,0.000111144254,0.00022535742,0.000010518017,0.00013143999,0.00013299861,0.000006366683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004485806,0.000034887973,0.0002731567,0.000020548405,0.0000423849,2.8449168e-7,0.00019841945,0.000030015392,0.9968565,0.00032283991,0.00048174884,0.0016943502],"study_design_scores_gemma":[0.00042059447,0.00019939423,0.0000055078553,0.000056271114,0.000015709484,0.0000016431287,0.00021844552,0.00027191252,0.9504597,0.0001265762,0.04800562,0.00021861905],"about_ca_topic_score_codex":0.000012134317,"about_ca_topic_score_gemma":0.0000018864124,"teacher_disagreement_score":0.04752387,"about_ca_system_score_codex":0.000015840618,"about_ca_system_score_gemma":0.000031865784,"threshold_uncertainty_score":0.7942663},"labels":[],"label_agreement":null},{"id":"W2785091002","doi":"10.1523/jneurosci.2673-17.2018","title":"Loss of eIF4E Phosphorylation Engenders Depression-like Behaviors via Selective mRNA Translation","year":2018,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Wellcome Trust; National Alliance for Research on Schizophrenia and Depression","keywords":"EIF4E; Phosphorylation; Cell biology; Kinase; Protein kinase A; MAPK/ERK pathway; Biology; Neuroscience; Translation (biology); Messenger RNA; Biochemistry","score_opus":0.018507680019059742,"score_gpt":0.2733259455900809,"score_spread":0.25481826557102116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2785091002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9423753,0.00015321453,0.056718342,0.00001943085,0.0006151122,0.000053410786,0.0000015781429,0.0000018428167,0.00006177512],"genre_scores_gemma":[0.9984119,0.00007484917,0.0012712958,0.000074598865,0.00013438587,6.416461e-7,8.0428424e-7,0.0000073685396,0.000024140552],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991743,0.00004620777,0.0002598625,0.0001512937,0.00024904165,0.0001193082],"domain_scores_gemma":[0.99929684,0.000008945456,0.00030480235,0.00009396373,0.00023347326,0.000061949875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002601501,0.00007431629,0.00009990011,0.000059550126,0.00008191653,0.000012582679,0.0001705295,0.000063330444,0.0000122028805],"category_scores_gemma":[0.00004675891,0.00006268584,0.00007889069,0.00014963257,0.00010767206,0.00001899718,0.000017769897,0.00008417536,4.6551844e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007197322,0.000035495585,0.0017763819,0.0000022865731,0.000002735565,0.0000020589907,0.00013692198,0.0001405205,0.9919757,0.0000019834254,0.000041919808,0.0058120117],"study_design_scores_gemma":[0.00023224558,0.0007299878,0.006482138,0.000012480558,0.000014074671,0.00006340121,0.000032154938,0.00051146373,0.9911394,0.00006299001,0.0006537849,0.0000658805],"about_ca_topic_score_codex":0.0000036423046,"about_ca_topic_score_gemma":0.0000020967511,"teacher_disagreement_score":0.05603662,"about_ca_system_score_codex":0.0000089121,"about_ca_system_score_gemma":0.00006873568,"threshold_uncertainty_score":0.25562543},"labels":[],"label_agreement":null},{"id":"W2785235690","doi":"10.1016/j.molmed.2017.12.004","title":"Focusing on the Opioid System for Addiction Biomarker Discovery","year":2018,"lang":"en","type":"review","venue":"Trends in Molecular Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Fondation Fyssen; Fondation FondaMental","keywords":"Addiction; Biomarker; Opioid; Medicine; Biomarker discovery; Bioinformatics; Neuroscience; Disease; Epigenetics; Mood disorders; Mood; Psychiatry; Psychology; Anxiety; Receptor; Biology; Internal medicine; Proteomics; Gene; Genetics","score_opus":0.04632176469486183,"score_gpt":0.33500936063032605,"score_spread":0.2886875959354642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2785235690","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009299795,0.9822576,0.014741595,0.00005865083,0.0010834668,0.000565817,0.000053996828,0.000017573177,0.0011282858],"genre_scores_gemma":[0.0011132088,0.9931412,0.0005015193,0.00020770541,0.0018438963,0.00045473882,0.0016195839,0.00015330235,0.00096484175],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979671,0.00022076286,0.0005834057,0.00063621905,0.00025420322,0.00033828637],"domain_scores_gemma":[0.99884933,0.00007090203,0.00030582445,0.0006580344,0.00005367329,0.00006222428],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000799075,0.00044542117,0.0008348588,0.00028395245,0.000104108214,0.00003068856,0.00035446492,0.00041337492,0.00006283123],"category_scores_gemma":[0.00012967431,0.00026097306,0.00043117098,0.00032919634,0.000116190786,0.0000031462719,0.00007995501,0.00019193944,0.000006102649],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058368438,0.00003312039,1.6701425e-7,0.0017330296,0.00032043832,0.000017361357,0.00002459602,0.0000022190104,0.01875651,0.0011117401,0.0059614656,0.971981],"study_design_scores_gemma":[0.00044444474,0.0005044821,5.4876733e-7,0.010577988,0.00041439966,0.000028099535,0.000038687867,0.0000283052,0.0059278314,0.000026470541,0.981716,0.00029276183],"about_ca_topic_score_codex":0.000013089939,"about_ca_topic_score_gemma":0.0000054300517,"teacher_disagreement_score":0.9757545,"about_ca_system_score_codex":0.000086237465,"about_ca_system_score_gemma":0.00006916149,"threshold_uncertainty_score":0.99998426},"labels":[],"label_agreement":null},{"id":"W2785390527","doi":"10.1016/j.bpj.2017.11.066","title":"Resolving Dopamine Receptor Dynamics with Spatial, Temporal, and Spectral Sampling","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Biophysics; Dopamine; Chemistry; Temporal resolution; Receptor; Biology; Endocrinology; Biochemistry; Physics","score_opus":0.010746350918028391,"score_gpt":0.24174040997965837,"score_spread":0.23099405906162998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2785390527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9187905,0.00005972848,0.08056127,0.00016856604,0.00020271841,0.000059254577,0.000007517622,0.000009530294,0.00014087491],"genre_scores_gemma":[0.981269,0.00008517017,0.015520347,0.00007933599,0.0028735264,0.0000016073224,0.000024895095,0.000027061704,0.00011908363],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910605,0.000035558525,0.00017793926,0.0002527366,0.00016124349,0.0002664449],"domain_scores_gemma":[0.9994676,0.000008815055,0.000108225104,0.00013702238,0.00011230353,0.00016603466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014251363,0.00015578164,0.0001517726,0.000033639848,0.00024274993,0.000114277864,0.000121178775,0.000085431355,0.00008435719],"category_scores_gemma":[0.000026265618,0.00011721413,0.000058270853,0.00006605041,0.00014066728,0.000008414648,0.000062008265,0.00017226463,0.0000081870585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016244638,0.000037139394,0.0006515285,0.000004748606,0.00003660288,0.000005001991,0.00002191467,0.0000042066968,0.99426496,0.00017039053,0.00018451508,0.004456538],"study_design_scores_gemma":[0.00089921884,0.0031822613,0.00092337944,0.00008580566,0.00003395408,0.00028758563,0.00018391079,0.0022812358,0.98224485,0.00016886178,0.009273461,0.0004355027],"about_ca_topic_score_codex":0.000029564562,"about_ca_topic_score_gemma":0.000042979245,"teacher_disagreement_score":0.06504093,"about_ca_system_score_codex":0.000022374954,"about_ca_system_score_gemma":0.000046385285,"threshold_uncertainty_score":0.47798535},"labels":[],"label_agreement":null},{"id":"W2787051453","doi":"10.7554/elife.33273","title":"Orphan receptor GPR158 controls stress-induced depression","year":2018,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Deafness and Other Communication Disorders; National Heart, Lung, and Blood Institute; National Institutes of Health; Max-Planck-Gesellschaft; Canadian Institutes of Health Research; National Institute for Health and Care Research; National Institute on Drug Abuse; University of Iowa; National Institute of Mental Health; Merck","keywords":"Chronic stress; Prefrontal cortex; Regulator; Antidepressant; Neuroscience; Social defeat; Glucocorticoid receptor; Depression (economics); AMPA receptor; Major depressive disorder; Receptor; Downregulation and upregulation; Anxiety; Psychology; Mood disorders; Hippocampus; Biology; Internal medicine; Medicine; Psychiatry; Amygdala; Glutamate receptor; Cognition; Gene; Genetics","score_opus":0.011147204369668283,"score_gpt":0.2585524811915712,"score_spread":0.24740527682190291,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2787051453","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99276024,0.00036267334,0.0036888216,0.00007681936,0.00087758724,0.0001601541,0.000019358922,0.00002831148,0.0020260466],"genre_scores_gemma":[0.9942234,0.00005655448,0.001708785,0.0005168208,0.0024580364,0.000013436679,0.000080722566,0.000027672315,0.00091454934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989954,0.000054532935,0.00017751135,0.00033488852,0.00018068163,0.00025695795],"domain_scores_gemma":[0.99934417,0.000008332317,0.00007695778,0.00031101855,0.00013811955,0.00012139298],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016986039,0.00014309077,0.00013674189,0.000026250818,0.00011741615,0.00003312552,0.0001853184,0.0001732128,0.00078178354],"category_scores_gemma":[0.000094572286,0.0001229626,0.000077390214,0.00005224594,0.000034914767,0.000003890483,0.00008769513,0.000071783106,0.00023539568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007771215,0.000029119432,0.0012318358,0.0000032002463,0.000026385891,5.732814e-7,0.000024882644,0.0000016009353,0.98857576,0.000060837363,0.0059260684,0.0040420154],"study_design_scores_gemma":[0.0004945224,0.0002969867,0.00030706252,0.000020571133,0.000007357442,0.0000021465535,0.000033353343,0.00004609096,0.8945654,0.000014415715,0.10405946,0.00015261483],"about_ca_topic_score_codex":0.000016809627,"about_ca_topic_score_gemma":0.000014920344,"teacher_disagreement_score":0.09813339,"about_ca_system_score_codex":0.0000084931235,"about_ca_system_score_gemma":0.000043555792,"threshold_uncertainty_score":0.85599816},"labels":[],"label_agreement":null},{"id":"W2789626204","doi":"10.1016/j.bpj.2017.11.264","title":"Insights into Sodium Channel Gating Enabled by Transplantation of an Aryl Sulfonamide Drug Binding Site in Combination with Genetically-Encoded Cross Linking","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Xenon Pharmaceuticals (Canada)","funders":"","keywords":"Sodium channel; Chemistry; Biophysics; Gating; Mutant; Biochemistry; Sodium; Biology","score_opus":0.006049512572581451,"score_gpt":0.23824597131302375,"score_spread":0.23219645874044229,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2789626204","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98040676,0.00004079757,0.019284558,0.000023884963,0.00010597215,0.00009931124,0.000007124292,0.000006188563,0.000025431462],"genre_scores_gemma":[0.9970469,0.00006689056,0.00224531,0.000038924427,0.0003802449,0.000004449826,0.0001800853,0.000021835633,0.000015350297],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886775,0.00008211553,0.00033381933,0.0002539836,0.00024259354,0.00021974044],"domain_scores_gemma":[0.99938446,0.000015976228,0.0001991736,0.00010475512,0.00019147883,0.00010413315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021438507,0.00015014021,0.00017749945,0.00007546546,0.00018722491,0.00007770573,0.00014805136,0.00010969689,0.000007820737],"category_scores_gemma":[0.000014278327,0.00012523,0.000056388522,0.00014608132,0.000102366015,0.000030338397,0.000023869938,0.00017830498,0.0000025799948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002719494,0.00013878908,0.00032388396,0.000026408065,0.000018337267,0.0000074302593,0.000876747,0.00014066255,0.9975947,0.00005819238,0.0000051955953,0.0005376794],"study_design_scores_gemma":[0.0013145878,0.00084471336,0.000589365,0.00011887638,0.000014959341,0.000017669825,0.00011385075,0.0070366277,0.9893682,0.00038416198,0.00002194389,0.00017506815],"about_ca_topic_score_codex":0.000027765223,"about_ca_topic_score_gemma":0.00003931369,"teacher_disagreement_score":0.017039249,"about_ca_system_score_codex":0.000024725652,"about_ca_system_score_gemma":0.0000527792,"threshold_uncertainty_score":0.5106731},"labels":[],"label_agreement":null},{"id":"W2789703461","doi":"10.1016/j.bpj.2017.11.2936","title":"Bioluminescence Resonance Energy Transfer (BRET)-based Imaging of G-Protein Coupled Receptor Signaling and Trafficking","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Förster resonance energy transfer; Bioluminescence; Biophysics; Chemistry; Luciferase; Fluorescence; Folate receptor; Autofluorescence; Luminescence; Cell biology; Biochemistry; Transfection; Biology; Cancer cell; Materials science; Physics","score_opus":0.007558990765373141,"score_gpt":0.21889551853739647,"score_spread":0.21133652777202333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2789703461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8954542,0.00045995958,0.103769384,0.000082742896,0.00013969134,0.000053850665,0.0000066547964,0.000008517511,0.000024964229],"genre_scores_gemma":[0.9957467,0.00005439597,0.0029980943,0.00012879743,0.0009965738,0.0000038420767,0.0000083687255,0.00002533549,0.00003794531],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988699,0.000069803384,0.00030350138,0.00028585418,0.0001993975,0.0002715398],"domain_scores_gemma":[0.99942696,0.000014408124,0.00009310194,0.00013862365,0.00019622533,0.00013065337],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021203398,0.0001722616,0.00020744566,0.000048984173,0.00016811317,0.000048175654,0.00017214417,0.0000876651,0.00006131952],"category_scores_gemma":[0.00003275347,0.00015107317,0.00012774326,0.00011459654,0.00022453592,0.000009759164,0.000027750953,0.00011710577,0.0000013411079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017716373,0.000050852137,0.00007115027,0.0000111325035,0.000015930638,0.00000298659,0.000031925163,0.000011390118,0.9936603,0.00035366393,0.00004222933,0.005571292],"study_design_scores_gemma":[0.0005924509,0.00040207495,0.000037418682,0.00013371081,0.000013182403,0.000015354055,0.00004478089,0.004928137,0.9915157,0.00004310457,0.0020798054,0.0001942932],"about_ca_topic_score_codex":0.000015522028,"about_ca_topic_score_gemma":0.0000021753274,"teacher_disagreement_score":0.100771286,"about_ca_system_score_codex":0.000010990702,"about_ca_system_score_gemma":0.000072323994,"threshold_uncertainty_score":0.61605847},"labels":[],"label_agreement":null},{"id":"W2791505431","doi":"10.1073/pnas.1721896115","title":"G <sub>i</sub> - and G <sub>s</sub> -coupled GPCRs show different modes of G-protein binding","year":2018,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"U.S. National Library of Medicine; National Institute of General Medical Sciences; National Eye Institute; Canada Excellence Research Chairs, Government of Canada; National Institutes of Health; National Science Foundation","keywords":"G protein-coupled receptor; Rhodopsin; Heterotrimeric G protein; G protein; Transducin; Transmembrane domain; Biophysics; Protein structure; Chemistry; G protein-coupled receptor kinase; Biology; Transmembrane protein; Ligand (biochemistry); Biochemistry; Receptor; Retinal","score_opus":0.023289578604448066,"score_gpt":0.26095524918902585,"score_spread":0.23766567058457777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791505431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991082,0.00020136288,0.00002688298,0.00022407703,0.000020529145,0.00016467224,0.000012283842,0.0000041006847,0.00023790107],"genre_scores_gemma":[0.9991592,0.00011869838,0.0005115051,0.000051961033,0.00012857928,0.00000968797,5.928822e-7,0.0000067366786,0.00001305149],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99862975,0.000007445362,0.00028902228,0.0002945943,0.0006079513,0.00017123403],"domain_scores_gemma":[0.99929005,0.000021161602,0.00036589656,0.000013529838,0.00026563075,0.00004375497],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007290107,0.0001231294,0.00017087234,0.00010714999,0.00018161995,0.00002309504,0.00041980887,0.00013120477,0.0000039353454],"category_scores_gemma":[0.0002430306,0.000084833344,0.0000779578,0.00023945513,0.0007426644,0.000029013363,0.00019906009,0.00008734446,3.8712164e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027777956,0.000024327492,0.00048669285,0.000050923893,0.000019272073,2.2456963e-9,0.000052249477,0.00001360624,0.99451613,0.0041035214,0.00003487905,0.00067059934],"study_design_scores_gemma":[0.00016801183,0.00016839744,0.0018637376,0.00010909547,0.000011027329,0.000002625441,0.00012545742,0.0014551725,0.9895473,0.006443563,0.000009835609,0.00009577327],"about_ca_topic_score_codex":0.0000016903017,"about_ca_topic_score_gemma":2.0571544e-7,"teacher_disagreement_score":0.004968845,"about_ca_system_score_codex":0.000010782833,"about_ca_system_score_gemma":0.000025437987,"threshold_uncertainty_score":0.34594032},"labels":[],"label_agreement":null},{"id":"W2791521348","doi":"10.1016/j.bpj.2017.11.270","title":"Structural Insights into the STAC Adaptor Protein and Voltage-Gated Calcium Channel Interaction","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"RYR1; Ryanodine receptor; Chemistry; Skeletal muscle; Signal transducing adaptor protein; Isothermal titration calorimetry; Depolarization; Biophysics; Allosteric regulation; Membrane protein; Calcium-binding protein; EF hand; Cell biology; Biochemistry; Calcium; Biology; Receptor; Anatomy; Membrane","score_opus":0.015119701552013762,"score_gpt":0.2586452498511325,"score_spread":0.24352554829911877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791521348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947208,0.000093817136,0.0044500553,0.0001764327,0.0003949273,0.000115320996,0.0000017676781,0.0000068794798,0.000040005634],"genre_scores_gemma":[0.99697125,0.000022520064,0.000180543,0.00010089371,0.0025650677,0.0000041000453,0.000008323959,0.000014653609,0.00013262533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926686,0.00006409842,0.00016155653,0.00019140805,0.00014198765,0.00017411489],"domain_scores_gemma":[0.99951994,0.0000060419297,0.00010074818,0.00012412018,0.00013862741,0.000110503366],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000084702035,0.0001326104,0.00010402719,0.000025261856,0.00034252057,0.00010171822,0.00013797957,0.000088199784,0.000032787673],"category_scores_gemma":[0.000028788243,0.000080006634,0.000068217596,0.000060348455,0.00012365027,0.000013025364,0.00008128776,0.00019997658,0.0000073089614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011314474,0.000013117939,0.000004373313,0.0000030346473,0.00003403272,0.000002309455,0.00029107256,0.000002945617,0.9968125,0.0001607566,0.00017081047,0.002391871],"study_design_scores_gemma":[0.00026471823,0.00059504935,0.00011095509,0.00001955997,0.000011123536,0.00003339315,0.0002854457,0.0016574642,0.99042624,0.0004895007,0.0059786667,0.00012787331],"about_ca_topic_score_codex":0.0000250415,"about_ca_topic_score_gemma":0.000007900064,"teacher_disagreement_score":0.006386281,"about_ca_system_score_codex":0.000015634567,"about_ca_system_score_gemma":0.000031304902,"threshold_uncertainty_score":0.3262576},"labels":[],"label_agreement":null},{"id":"W2791577277","doi":"10.3389/fnsyn.2018.00002","title":"Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D2 Dopamine Receptor","year":2018,"lang":"en","type":"article","venue":"Frontiers in Synaptic Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; University of Toronto; Centre for Addiction and Mental Health","funders":"National Center for Advancing Translational Sciences; National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Dopamine receptor D2; Internalization; Arrestin; Functional selectivity; Agonist; G protein-coupled receptor; Signal transduction; Dopamine; Neuroscience; Biological pathway; Receptor; Dopamine receptor; Biology; Chemistry; Cell biology; Biochemistry; Gene; Gene expression","score_opus":0.014843218222330484,"score_gpt":0.24597640220210193,"score_spread":0.23113318397977145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791577277","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94940305,0.000045178484,0.04912315,0.000032968892,0.0006821084,0.0006558419,0.000048474725,0.0000041290364,0.0000051211496],"genre_scores_gemma":[0.9859666,0.0000027623316,0.013808676,0.000091549075,0.000046919693,0.000030943957,0.000003810294,0.000016398633,0.000032336924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998653,0.0001434773,0.0003233823,0.00041329436,0.00022034743,0.00024649515],"domain_scores_gemma":[0.9990872,0.00001680016,0.0003478563,0.00036658088,0.0001273851,0.000054170916],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039286932,0.00014739516,0.00023370486,0.000067679226,0.00010448792,0.000016465676,0.00041296068,0.0001026356,0.0000042328493],"category_scores_gemma":[0.00062939274,0.000119405944,0.00009101694,0.00024388281,0.00055070594,0.000011290947,0.00008178495,0.00007313647,8.544757e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000965608,0.00001819878,0.002852771,0.00004988302,0.0000046599052,4.9462085e-7,0.000039175906,0.000085041196,0.9961628,0.000025213509,0.00002613869,0.00063910853],"study_design_scores_gemma":[0.00034123223,0.000510354,0.00087771233,0.00008799304,0.000010449974,0.0000021026376,0.000026639207,0.0027659067,0.9947364,0.00045739347,0.000059225906,0.00012460773],"about_ca_topic_score_codex":0.000013790506,"about_ca_topic_score_gemma":0.000004909554,"teacher_disagreement_score":0.036563575,"about_ca_system_score_codex":0.000018480316,"about_ca_system_score_gemma":0.0001236193,"threshold_uncertainty_score":0.4869233},"labels":[],"label_agreement":null},{"id":"W2791787748","doi":"10.1073/pnas.1716224115","title":"Monitoring ligand-dependent assembly of receptor ternary complexes in live cells by BRETFect","year":2018,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Institute of Cancer Research; Institute of Infection and Immunity; Canadian Institutes of Health Research; Government of Canada","keywords":"G protein-coupled receptor; Effector; Receptor; Ternary complex; Cell biology; Ligand (biochemistry); Signal transduction; Biology; G protein; Computational biology; Biophysics; Chemistry; Biochemistry; Enzyme","score_opus":0.024787661271539852,"score_gpt":0.2927837625977455,"score_spread":0.26799610132620566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791787748","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988621,0.00024379756,0.000004921297,0.0001247361,0.000049505306,0.000089724985,0.000014336631,0.0000018723141,0.00060903706],"genre_scores_gemma":[0.9984279,0.0000866105,0.0011936733,0.00003195746,0.00015613396,0.0000035683195,2.158611e-7,0.000003836872,0.00009605147],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989388,0.0000069373073,0.00025037915,0.00019603172,0.00049299333,0.00011487319],"domain_scores_gemma":[0.9994733,0.000022448334,0.00028659,0.000008169252,0.0001883089,0.000021190848],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00075059605,0.00007348822,0.000117434916,0.000060433656,0.00006699328,0.000010520973,0.0004890075,0.000085932996,0.000012107368],"category_scores_gemma":[0.00009780147,0.000053662578,0.000052370087,0.0001784292,0.00031703917,0.000019194478,0.00013164594,0.00006929689,8.356687e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018622784,0.000029011662,0.004976852,0.000020381076,0.000008774678,1.3263081e-9,0.000095314426,0.000015072282,0.9941025,0.00021139847,0.00035217108,0.00016994592],"study_design_scores_gemma":[0.00011815587,0.0001678508,0.002475205,0.000097431235,0.0000030798838,0.0000010817197,0.00018779859,0.00009573101,0.99585575,0.00085796,0.00008155228,0.000058379108],"about_ca_topic_score_codex":0.000017098066,"about_ca_topic_score_gemma":9.214665e-8,"teacher_disagreement_score":0.0025016465,"about_ca_system_score_codex":0.000011231412,"about_ca_system_score_gemma":0.00002023482,"threshold_uncertainty_score":0.21882965},"labels":[],"label_agreement":null},{"id":"W2791870770","doi":"10.1038/s41386-018-0033-9","title":"M1-positive allosteric modulators lacking agonist activity provide the optimal profile for enhancing cognition","year":2018,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; National Institutes of Health; Vanderbilt University Medical Center; Vanderbilt University; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Autism Speaks; CHDI Foundation; AstraZeneca; Bristol-Myers Squibb","keywords":"Agonist; Neuroscience; Allosteric regulation; Allosteric modulator; Prefrontal cortex; Muscarinic acetylcholine receptor M1; Cognition; Receptor; Muscarinic acetylcholine receptor; Psychology; Pharmacology; Medicine; Internal medicine","score_opus":0.013803992959119972,"score_gpt":0.29668139986558045,"score_spread":0.28287740690646046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2791870770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9698835,0.00005714387,0.026442783,0.00023413099,0.0015516807,0.00091725064,0.000038515107,0.000029137025,0.000845853],"genre_scores_gemma":[0.99517095,0.000028433178,0.00084468396,0.0016321288,0.0015516564,0.00023687021,0.00004958639,0.000047205842,0.00043845654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986336,0.0001808625,0.00019156195,0.00050591415,0.00010195218,0.00038606624],"domain_scores_gemma":[0.99931985,0.0000703694,0.000151542,0.00018995446,0.00019354153,0.00007477009],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024054555,0.00019870453,0.00015343649,0.000036526664,0.0003945596,0.00004693115,0.00021426225,0.00013497668,0.00009890336],"category_scores_gemma":[0.00007357736,0.0001638884,0.00011375972,0.000099432575,0.00015917643,0.000010356509,0.00009475393,0.00015056957,0.00002307454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004934925,0.00006340896,0.000014826308,0.000013650181,0.00006342994,0.0000025946017,0.000094796196,0.000035806665,0.99194247,0.000020498288,0.0021201104,0.005134939],"study_design_scores_gemma":[0.0009274747,0.0012384076,0.0002947024,0.000008046057,0.000062799474,0.000025231562,0.000045936064,0.0014986136,0.98140234,0.0000368189,0.0143189635,0.00014069275],"about_ca_topic_score_codex":0.00000444063,"about_ca_topic_score_gemma":0.000010896311,"teacher_disagreement_score":0.0255981,"about_ca_system_score_codex":0.0000152612,"about_ca_system_score_gemma":0.000063013074,"threshold_uncertainty_score":0.6683175},"labels":[],"label_agreement":null},{"id":"W2792111182","doi":"10.1038/s41598-018-21899-5","title":"Reactive Oxygen Species Mediate the Suppression of Arterial Smooth Muscle T-type Ca2+ Channels by Angiotensin II","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Libin Cardiovascular Institute of Alberta; Robarts Clinical Trials; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; Alberta Innovates - Health Solutions","keywords":"Angiotensin II; NADPH oxidase; Apocynin; NOX1; Transient receptor potential channel; Vascular smooth muscle; Chemistry; Reactive oxygen species; Internal medicine; Gq alpha subunit; Colocalization; TRPC3; Endocrinology; Cell biology; Biophysics; Receptor; Biology; G protein; Medicine; Biochemistry; TRPC; Smooth muscle","score_opus":0.011600765183575947,"score_gpt":0.23108731441671862,"score_spread":0.21948654923314267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792111182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98764765,0.00020464725,0.0002235596,0.00013123555,0.011057783,0.00017941541,0.000010932456,0.000009157536,0.0005356357],"genre_scores_gemma":[0.9948164,0.000009983609,0.0001647138,0.0000370898,0.0006988989,0.000004206742,0.00021011596,0.000014528331,0.0040440625],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986288,0.000053079235,0.00029489337,0.00049617665,0.0002925821,0.00023447198],"domain_scores_gemma":[0.99873376,0.0000070993233,0.00026699057,0.0006172576,0.0003089006,0.000065972454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074112386,0.00012286083,0.00014101858,0.000035886624,0.0004021875,0.00007013056,0.00015505688,0.000108170905,0.00024531703],"category_scores_gemma":[0.00012949959,0.00008319298,0.00008517639,0.00015634349,0.00035685967,0.000008289327,0.00016602245,0.000051062456,0.000004277498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030804866,0.000027846387,0.0000188503,0.000002099545,0.000013602097,0.000005479507,0.0003791119,0.000003518191,0.9201633,0.0000070645424,0.07900339,0.0003449732],"study_design_scores_gemma":[0.00006804455,0.00013311744,0.00012425473,0.000011541921,0.00000900983,0.000010160037,0.0000966976,0.00001773406,0.7507554,0.0004378188,0.24825409,0.00008210325],"about_ca_topic_score_codex":0.000026936743,"about_ca_topic_score_gemma":0.000010267901,"teacher_disagreement_score":0.16940781,"about_ca_system_score_codex":0.000008633341,"about_ca_system_score_gemma":0.00008102558,"threshold_uncertainty_score":0.33925113},"labels":[],"label_agreement":null},{"id":"W2792121881","doi":"10.1016/j.bpj.2017.11.1333","title":"Diverse Diffusion Regimes of Individual M2 Muscarinic Receptors and Gi Proteins in Live Cells","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Receptor; G protein-coupled receptor; Biophysics; Cell biology; Muscarinic acetylcholine receptor; Biology; G protein; Chemistry; Biochemistry","score_opus":0.011555191126026059,"score_gpt":0.23538216529209247,"score_spread":0.2238269741660664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792121881","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9992226,0.0000588525,0.00025131577,0.000027007802,0.00025056937,0.00010018848,0.000006381753,0.0000026772211,0.00008040593],"genre_scores_gemma":[0.9979792,0.00018540786,0.0009939715,0.00004082815,0.0006762401,0.000002318053,0.0000055161245,0.000011058156,0.00010542125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917877,0.000070236616,0.00020336786,0.00019162313,0.00017758163,0.00017844867],"domain_scores_gemma":[0.99958026,0.000008961884,0.00013137613,0.00010905464,0.000071116214,0.00009921164],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017815297,0.00011281519,0.00015580482,0.00005184969,0.00007828471,0.000026144471,0.00015357374,0.00011719866,0.000098804485],"category_scores_gemma":[0.000026239526,0.00009150615,0.00007892735,0.00007004173,0.00013947206,0.0000069416974,0.00016158914,0.00014377804,0.000007295595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008276079,0.000097430086,0.0003973064,0.000006738286,0.000023186094,0.000003355571,0.0003277973,0.0000011752575,0.99229914,0.000048399936,0.00021554,0.0064971526],"study_design_scores_gemma":[0.00057312346,0.0010667886,0.002274318,0.000049788836,0.000015488933,0.000012121871,0.0005194743,0.000032482905,0.9942451,0.00011811584,0.00096513424,0.0001280344],"about_ca_topic_score_codex":0.000019006182,"about_ca_topic_score_gemma":0.0000065611544,"teacher_disagreement_score":0.006369118,"about_ca_system_score_codex":0.000008493572,"about_ca_system_score_gemma":0.000036335583,"threshold_uncertainty_score":0.37315124},"labels":[],"label_agreement":null},{"id":"W2792210271","doi":"10.1016/j.marenvres.2018.03.006","title":"Characterization of a β2 adrenergic receptor protein precursor in the European eel ( Anguilla anguilla ) and its tissue distribution across silvering","year":2018,"lang":"en","type":"article","venue":"Marine Environmental Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Università di Bologna","keywords":"Biology; Tissue distribution; Ontogeny; Fish <Actinopterygii>; Messenger RNA; Receptor; Gene; Distribution (mathematics); Adrenergic; Adrenergic receptor; Internal medicine; Cell biology; Zoology; Endocrinology; Fishery; Biochemistry","score_opus":0.016589833225236637,"score_gpt":0.289925263915913,"score_spread":0.27333543069067634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792210271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99872434,0.0000958357,0.00014978727,0.00004213485,0.000029727973,0.00041254624,0.00008401691,0.0000030900517,0.00045851074],"genre_scores_gemma":[0.9981819,0.00016415343,0.00007530169,0.0000106417565,0.00022241939,0.000030195024,0.00064205175,0.000018343479,0.0006550041],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866706,0.00036458072,0.00017144773,0.00028573597,0.000236412,0.00027476894],"domain_scores_gemma":[0.99966615,0.00000977785,0.000050963157,0.00020615781,0.000019462144,0.00004749705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001087683,0.00010201907,0.00008749498,0.000025937083,0.00012950612,0.000032659944,0.00020000915,0.000064697444,0.00013927517],"category_scores_gemma":[0.000076488024,0.00008317125,0.000022656515,0.00010089894,0.00017546357,0.000008220667,0.00047878025,0.00011708116,0.000020574173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000638006,0.0000625911,0.0031746945,0.000015874828,0.0000060895145,0.0000017745332,0.0002237266,9.5302283e-7,0.983883,0.000030097193,0.0000161883,0.012521173],"study_design_scores_gemma":[0.00026183715,0.00043204983,0.14117719,0.000018057766,0.000001348181,0.000004204941,0.00015904785,0.000054485754,0.8517188,0.000012900076,0.006077433,0.00008263124],"about_ca_topic_score_codex":0.000020189815,"about_ca_topic_score_gemma":0.000018787443,"teacher_disagreement_score":0.1380025,"about_ca_system_score_codex":0.000028583003,"about_ca_system_score_gemma":0.000008654768,"threshold_uncertainty_score":0.33916253},"labels":[],"label_agreement":null},{"id":"W2792843706","doi":"10.1016/j.neuron.2018.04.021","title":"A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action","year":2018,"lang":"en","type":"article","venue":"Neuron","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":299,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; University of California, San Francisco; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Institute on Drug Abuse; M.S.I. Foundation","keywords":"Internalization; Endosome; Golgi apparatus; Receptor; Neuroscience; Neuromodulation; Opioid peptide; Biology; Cell biology; Chemistry; Opioid; Biochemistry","score_opus":0.028610798766820128,"score_gpt":0.2747069183605019,"score_spread":0.24609611959368174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792843706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952843,0.000098809105,0.003661959,0.0000659553,0.00029636995,0.000114866576,0.0000035033831,0.00000964252,0.00046456917],"genre_scores_gemma":[0.9973204,0.00010528521,0.0015077196,0.00021153713,0.00032531578,0.000005142957,0.000020120358,0.000015183022,0.0004892724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930876,0.000062944135,0.00017908525,0.00022223892,0.00010374687,0.00012320442],"domain_scores_gemma":[0.9994912,0.00000836688,0.00009109236,0.00021838068,0.00014864074,0.00004229561],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012280553,0.00008431994,0.00008765912,0.000030235971,0.000041667005,0.000010231182,0.000091026275,0.0000761962,0.00005847932],"category_scores_gemma":[0.000085820975,0.00007901097,0.000043754473,0.000075872806,0.00004891883,0.000002356805,0.000033538883,0.000039574716,0.000019319468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048364232,0.000023775016,0.00017270929,0.000015108128,0.0000061802366,2.6296868e-7,0.000037084625,0.000013882604,0.995068,0.00007740916,0.0006842031,0.0038529828],"study_design_scores_gemma":[0.00016070902,0.00038183617,0.001133787,0.000012228138,0.000008321507,0.000003486426,0.000021359754,0.00016588708,0.99003625,0.00010607832,0.007892062,0.0000779906],"about_ca_topic_score_codex":0.000013629584,"about_ca_topic_score_gemma":0.000009351207,"teacher_disagreement_score":0.0072078584,"about_ca_system_score_codex":0.0000049723494,"about_ca_system_score_gemma":0.000031957316,"threshold_uncertainty_score":0.32219738},"labels":[],"label_agreement":null},{"id":"W2792961926","doi":"10.1016/j.bpj.2017.11.1329","title":"Characterizing GPCR Allostery by NMR Spectroscopy","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Allosteric regulation; Chemistry; Lipid bilayer; Nuclear magnetic resonance spectroscopy; Membrane protein; Allosteric enzyme; Biophysics; Signal transduction; Biochemistry; Receptor; Biology; Membrane; Stereochemistry","score_opus":0.00885096626345978,"score_gpt":0.2451859379276373,"score_spread":0.23633497166417752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2792961926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98995894,0.00005892146,0.008523805,0.00024264798,0.00046252442,0.000044903023,0.000009187287,0.000009538355,0.00068955316],"genre_scores_gemma":[0.99270827,0.000082909806,0.0013757206,0.00073379127,0.0047046985,0.0000019993101,0.00002428709,0.000023763689,0.00034459293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911064,0.000042025767,0.00017997352,0.00021613657,0.00015783914,0.00029338116],"domain_scores_gemma":[0.9995198,0.000004204732,0.00009686323,0.00014786233,0.00007364689,0.00015759218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011706921,0.00013838518,0.00013244803,0.000021417125,0.00017413824,0.00009869634,0.0001892947,0.00009458154,0.00025632468],"category_scores_gemma":[0.00001624998,0.00011592554,0.00012650696,0.000048810853,0.00007256371,0.0000075863964,0.00006444516,0.00015238259,0.00009213041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059827154,0.000049424005,0.00003802796,0.0000018752987,0.000030931573,0.000003953886,0.000023520466,1.2935003e-7,0.993566,0.000045739387,0.0051851296,0.000995481],"study_design_scores_gemma":[0.00023359353,0.00064279966,0.000087913344,0.000012684537,0.000009089155,0.000057400262,0.000022415281,0.00003617894,0.9588439,0.0000643187,0.03983817,0.0001515512],"about_ca_topic_score_codex":0.0000018014414,"about_ca_topic_score_gemma":3.234893e-7,"teacher_disagreement_score":0.03472207,"about_ca_system_score_codex":0.000013917402,"about_ca_system_score_gemma":0.00003090718,"threshold_uncertainty_score":0.47273064},"labels":[],"label_agreement":null},{"id":"W2793475974","doi":"10.1080/14756366.2018.1437155","title":"Synthesis and biological evaluation of<i>N</i>-arylpiperazine derivatives of 4,4-dimethylisoquinoline-1,3(2<i>H</i>,4<i>H</i>)-dione as potential antiplatelet agents","year":2018,"lang":"en","type":"article","venue":"Journal of Enzyme Inhibition and Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Faculté de pharmacie, Université de Montréal; Narodowym Centrum Nauki; Uniwersytet Jagielloński Collegium Medicum","keywords":"Clopidogrel; Chemistry; Pharmacology; Aspirin; Mechanism of action; Receptor; Platelet; Alpha (finance); Platelet aggregation; Stereochemistry; In vitro; Medicine; Biochemistry; Internal medicine; Surgery","score_opus":0.02315334790137174,"score_gpt":0.2898049013742993,"score_spread":0.26665155347292757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793475974","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99569285,0.00254441,0.001161942,0.00011877171,0.00009763263,0.000070831644,0.000011353329,0.0000021253343,0.0003000767],"genre_scores_gemma":[0.99740285,0.0012028916,0.000731276,0.000092365524,0.0005232736,0.0000021954006,0.000018630337,0.000008860551,0.000017659026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987024,0.000088557244,0.0005217328,0.0001739222,0.00038887677,0.00012448628],"domain_scores_gemma":[0.99859446,0.000031244683,0.0004936323,0.00009459484,0.00067059783,0.000115461284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010298796,0.00013675014,0.00030718057,0.000052062183,0.000051312138,0.000007561462,0.00006548549,0.00017414754,0.0002759682],"category_scores_gemma":[0.0005301739,0.00010718061,0.000084768326,0.00007503152,0.00031801962,0.000013012164,0.000050746745,0.0001126479,2.9794634e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034761344,0.00006987183,0.00019818575,0.000059070506,0.00007527329,0.000006446326,0.000076685,0.0000073757105,0.99571896,0.000008365421,0.00027410378,0.0031580597],"study_design_scores_gemma":[0.0012872157,0.0007143422,0.0005129697,0.0002522789,0.0001175084,0.00046206065,0.00038124403,0.00009344084,0.9955183,0.00021420057,0.00034396184,0.00010242348],"about_ca_topic_score_codex":0.0000043142936,"about_ca_topic_score_gemma":3.4172135e-7,"teacher_disagreement_score":0.0030556363,"about_ca_system_score_codex":0.000008905078,"about_ca_system_score_gemma":0.00009668166,"threshold_uncertainty_score":0.43706983},"labels":[],"label_agreement":null},{"id":"W2793563466","doi":"10.1016/s0735-1097(18)32007-2","title":"ANGIOTENSIN RECEPTOR NEPRILYSIN INHIBITOR THERAPY PROMOTES EARLY ANGIOGENESIS AND IMPROVES MYOCARDIAL PERFUSION INHIBITING POST-INFARCT REMODELING","year":2018,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Neprilysin; Angiogenesis; Cardiology; Internal medicine; Ventricular remodeling; Perfusion; Myocardial infarction","score_opus":0.00794088630253179,"score_gpt":0.227714747996654,"score_spread":0.21977386169412222,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793563466","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966974,0.001039136,0.0008003349,0.0007100188,0.00050818996,0.00017311495,0.000032406875,0.000004035319,0.000035358084],"genre_scores_gemma":[0.9917083,0.00044037506,0.005199634,0.00027096935,0.0023209164,0.0000017040977,0.0000022384772,0.00002948195,0.000026422042],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984543,0.00035147238,0.00048840797,0.00024574186,0.00020755237,0.00025255833],"domain_scores_gemma":[0.9981834,0.000047237685,0.00073007075,0.0002520233,0.0007031539,0.00008406785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007113944,0.00018917168,0.00058870856,0.000107939144,0.00015897615,0.000013653495,0.00024267241,0.00011816309,0.000004086866],"category_scores_gemma":[0.00024034607,0.00012909873,0.00047145982,0.00020303298,0.0004580059,0.000012120243,0.00017998622,0.00013611304,5.7157285e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000737998,0.000010326366,0.002353486,0.0000030598515,0.00018703874,0.0000036392526,0.0000711814,0.00003071466,0.98537713,0.000007882159,0.0005038648,0.010713661],"study_design_scores_gemma":[0.0007187599,0.0037822241,0.005632457,0.00005266663,0.000069961425,0.00037706338,0.00040703526,0.00007964765,0.9849993,0.000076171724,0.0036038246,0.00020090026],"about_ca_topic_score_codex":0.000025889794,"about_ca_topic_score_gemma":0.00000200429,"teacher_disagreement_score":0.010512761,"about_ca_system_score_codex":0.000019602772,"about_ca_system_score_gemma":0.00015661342,"threshold_uncertainty_score":0.5264493},"labels":[],"label_agreement":null},{"id":"W2794351657","doi":"10.1139/y99-132","title":"Heterotrimeric G proteins in heart disease","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Heterotrimeric G protein; G protein; G protein-coupled receptor; G beta-gamma complex; Biology; GTPase-activating protein; GTP-binding protein regulators; Cell biology; G protein-coupled receptor kinase; Signal transduction","score_opus":0.008346955708737213,"score_gpt":0.24917491290267527,"score_spread":0.24082795719393804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794351657","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99702907,0.0019906992,0.000015196517,0.0005521279,0.00024443457,0.00009264473,0.0000067311703,8.437156e-7,0.000068252695],"genre_scores_gemma":[0.9975368,0.0001716953,0.00012360586,0.0016980811,0.00031549833,0.000006081299,0.000006221563,0.000007730864,0.00013429394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993159,0.00012593169,0.00017650065,0.00013064088,0.000024428093,0.0002265865],"domain_scores_gemma":[0.9995111,0.000008208088,0.000048464593,0.000055651974,0.00003135992,0.00034517483],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00012465284,0.000085714964,0.00015360511,0.000084421954,0.000059260823,0.000004625125,0.00009723545,0.00008491849,0.0038639673],"category_scores_gemma":[0.000008823434,0.00007945358,0.000048871796,0.000052628537,0.000103151564,0.000004966217,0.0000065546606,0.00014258536,0.000006149218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017362175,0.000015859316,0.001058763,0.000010835508,0.000019627461,0.000032256565,0.000033645243,0.00026003257,0.9958904,0.0000142751005,0.0015961666,0.0008945422],"study_design_scores_gemma":[0.0017427172,0.0010138985,0.016535645,0.000022057937,0.00003992111,0.00015834688,0.00002410365,0.00006924686,0.8424884,0.0017068128,0.13593024,0.00026859596],"about_ca_topic_score_codex":0.0001798104,"about_ca_topic_score_gemma":0.00019659263,"teacher_disagreement_score":0.15340196,"about_ca_system_score_codex":0.00001091366,"about_ca_system_score_gemma":0.00034006688,"threshold_uncertainty_score":0.99704665},"labels":[],"label_agreement":null},{"id":"W2795282787","doi":"10.1101/240903","title":"Visualization of class A GPCR oligomerization by image-based fluorescence fluctuation spectroscopy","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Julius-Maximilians-Universität Würzburg; Université Laval","keywords":"G protein-coupled receptor; Fluorescence spectroscopy; Chemistry; Receptor; Biophysics; Computational biology; Fluorescence; Biochemistry; Biology; Physics","score_opus":0.008632456454001921,"score_gpt":0.24091560586522168,"score_spread":0.23228314941121975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2795282787","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7025167,0.0006431822,0.29507935,0.000059564823,0.0007583595,0.00061198126,0.00024542122,0.00007194946,0.000013486253],"genre_scores_gemma":[0.98537534,0.00039536704,0.0135704735,0.00006547651,0.00037612102,0.00007156202,0.000029390123,0.00010987197,0.0000064227193],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978257,0.0001300963,0.00050183205,0.0008363176,0.0003659995,0.0003400768],"domain_scores_gemma":[0.9972094,0.0000108740605,0.000876209,0.0011359077,0.0006359766,0.00013160867],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039191128,0.00041997962,0.00040625254,0.00013810118,0.00017698937,0.00018079148,0.0005287722,0.0006031119,0.000047850514],"category_scores_gemma":[0.00030193655,0.0004775639,0.00015558975,0.00014168533,0.00013166161,0.000018698613,0.00021160673,0.00021152523,0.000008370271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056947945,0.00008684506,0.0007007008,0.00021823375,0.000057345347,0.0000014458972,0.0000030729109,0.0001467562,0.99819124,0.00021453362,0.00031989758,0.000002966934],"study_design_scores_gemma":[0.00045222044,0.00012818322,0.0014092944,0.00021607579,0.00006370722,4.6638586e-9,0.0000010958264,0.003419092,0.99261427,0.000003466663,0.0012256805,0.00046692998],"about_ca_topic_score_codex":0.000032989068,"about_ca_topic_score_gemma":0.0000011767896,"teacher_disagreement_score":0.2828586,"about_ca_system_score_codex":0.000064061576,"about_ca_system_score_gemma":0.000524208,"threshold_uncertainty_score":0.9997676},"labels":[],"label_agreement":null},{"id":"W2796415375","doi":"10.1016/bs.ircmb.2018.02.005","title":"The Dynamics of GPCR Oligomerization and Their Functional Consequences","year":2018,"lang":"en","type":"review","venue":"International review of cell and molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Biology; Allosteric regulation; Computational biology; Function (biology); PDZ domain; Obligate; Receptor; Viewpoints; Signal transduction; Neuroscience; Cell biology; Biochemistry; Ecology","score_opus":0.013416149951689974,"score_gpt":0.28994916256847914,"score_spread":0.27653301261678914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796415375","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016088747,0.9899602,0.008674292,0.000079412814,0.0002953899,0.0002352812,0.00010581781,0.0000017166833,0.0004869889],"genre_scores_gemma":[0.0008832266,0.9977256,0.00024000605,0.00011136015,0.000083702966,0.000026477284,0.0008188098,0.000013666026,0.00009713409],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989108,0.00015335128,0.0004936541,0.00026646082,0.000076276294,0.000099498626],"domain_scores_gemma":[0.9990308,0.00005979844,0.0005062739,0.0001654524,0.00020537786,0.000032278705],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003355887,0.00019338683,0.00051046297,0.000042807358,0.00004202586,0.000008989256,0.00021286086,0.00017713405,0.000026422269],"category_scores_gemma":[0.00012308035,0.00011435121,0.00020559826,0.00005098687,0.0003969352,0.0000019776232,0.00014157353,0.00007003666,7.9643996e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027119677,0.000043573935,0.000008860113,0.02186626,0.00068554794,0.0000012308273,0.000009165114,3.1594107e-7,0.12337891,0.040357154,0.00027535605,0.8133465],"study_design_scores_gemma":[0.00008900079,0.00019348276,4.6335688e-7,0.005633762,0.00011948337,0.00004577249,0.000010772945,0.000014413696,0.016647931,0.0009873395,0.97610676,0.00015084157],"about_ca_topic_score_codex":0.000003950676,"about_ca_topic_score_gemma":0.000002209445,"teacher_disagreement_score":0.9758314,"about_ca_system_score_codex":0.000007652749,"about_ca_system_score_gemma":0.000111332025,"threshold_uncertainty_score":0.4663107},"labels":[],"label_agreement":null},{"id":"W2796750185","doi":"10.1038/s41467-018-03314-9","title":"Mechanistic insights into allosteric regulation of the A2A adenosine G protein-coupled receptor by physiological cations","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":159,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Process Research Ortech (Canada); Hospital for Sick Children; Canada Research Chairs; University of Toronto","funders":"Core Research for Evolutional Science and Technology; National Institute of General Medical Sciences; Japan Science and Technology Agency; National Science Foundation; Compute Canada; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Los Alamos National Laboratory; National Nuclear Security Administration; University of Toronto; Laboratory Directed Research and Development; Canada Excellence Research Chairs, Government of Canada; U.S. Department of Energy","keywords":"Allosteric regulation; Adenosine; G protein-coupled receptor; Adenosine receptor; Adenosine A2A receptor; Chemistry; Receptor; Cell biology; Biophysics; Biochemistry; Computational biology; Biology; Agonist","score_opus":0.01199311572875665,"score_gpt":0.262296007005895,"score_spread":0.25030289127713834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2796750185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98720866,0.0043471344,0.0051175207,0.0017541874,0.0002796777,0.0007431485,0.000026366335,0.000027660233,0.0004956276],"genre_scores_gemma":[0.99206644,0.00015319741,0.0065442193,0.00021692475,0.00012461399,0.00007957292,0.00049967354,0.000015278723,0.00030009125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991442,0.00016852522,0.00023151777,0.00020973163,0.00013353051,0.00011250532],"domain_scores_gemma":[0.9980794,0.000021878348,0.0001810745,0.0013293988,0.00034991052,0.00003831897],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000113515234,0.00011916985,0.00011799391,0.000026719978,0.00039158852,0.000018690684,0.00086441665,0.0003172389,0.00008827178],"category_scores_gemma":[0.00020023421,0.00008529183,0.000071542374,0.00022946982,0.00022097779,0.000007645151,0.00036696266,0.0002533915,0.000010887662],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013476946,0.00007836207,0.000012789471,0.0000048272,0.000021756683,5.851004e-9,0.000089665555,0.0000021137118,0.99023753,0.006186867,0.0031876955,0.00016490294],"study_design_scores_gemma":[0.00018698312,0.00020093765,0.0007530405,0.000028179888,0.000021932396,9.175737e-7,0.00006835362,0.0006643285,0.95510584,0.0018528645,0.04097992,0.00013669328],"about_ca_topic_score_codex":0.000030645384,"about_ca_topic_score_gemma":0.0001367322,"teacher_disagreement_score":0.037792224,"about_ca_system_score_codex":0.000021678237,"about_ca_system_score_gemma":0.0000581033,"threshold_uncertainty_score":0.34781},"labels":[],"label_agreement":null},{"id":"W2797464049","doi":"10.7717/peerj.4593","title":"Evolution of dopamine receptors: phylogenetic evidence suggests a later origin of the DRD <sub>2l</sub> and DRD <sub>4rs</sub> dopamine receptor gene lineages","year":2018,"lang":"en","type":"article","venue":"PeerJ","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Fondo Nacional de Desarrollo Científico y Tecnológico; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Dopamine receptor; Biology; Dopamine; Phylogenetic tree; Monophyly; Dopaminergic; Receptor; Sister group; Clade; Genetics; Neuroscience; Gene","score_opus":0.013110142938055564,"score_gpt":0.24224081991888802,"score_spread":0.22913067698083245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2797464049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925474,0.0044457563,0.0016941759,0.00015500346,0.00069032004,0.00037915795,0.000042049327,0.000018883242,0.000027248037],"genre_scores_gemma":[0.99550456,0.0020925289,0.0011357199,0.0000550368,0.00087047234,0.000024079014,0.000045979286,0.000051471263,0.00022017662],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978252,0.00019028084,0.0005788802,0.00062106014,0.00037586925,0.00040871004],"domain_scores_gemma":[0.9983041,0.00006317304,0.00037887756,0.00064734975,0.00048008445,0.00012637736],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050913193,0.00033487217,0.00040675115,0.00009350055,0.0001348715,0.000028793665,0.00038787353,0.0002903529,0.000069192996],"category_scores_gemma":[0.0003523407,0.00026265302,0.00017964643,0.00028270693,0.0003798891,0.000017653858,0.00028004742,0.00015459015,0.00001527677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014845414,0.00007107992,0.0066392985,0.00008868535,0.000063093044,6.3455064e-7,0.00009240708,0.00004310001,0.9857797,0.00001829931,0.0008073114,0.0062479055],"study_design_scores_gemma":[0.0005241223,0.00080915063,0.0039068125,0.0002032984,0.000071717055,0.000017103393,0.000045337685,0.00019013224,0.9912195,0.000057577727,0.0026645865,0.00029064334],"about_ca_topic_score_codex":0.00005407036,"about_ca_topic_score_gemma":0.00007514497,"teacher_disagreement_score":0.005957262,"about_ca_system_score_codex":0.000045095476,"about_ca_system_score_gemma":0.00012308547,"threshold_uncertainty_score":0.9999826},"labels":[],"label_agreement":null},{"id":"W2799534791","doi":"10.1016/j.tibs.2018.04.003","title":"Emerging Paradigm of Intracellular Targeting of G Protein-Coupled Receptors","year":2018,"lang":"en","type":"review","venue":"Trends in Biochemical Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; The Wellcome Trust DBT India Alliance; Canada Research Chairs; Wellcome Trust","keywords":"G protein-coupled receptor; Intracellular; Biology; Aptamer; Allosteric regulation; Receptor; Extracellular; Cell biology; Signal transduction; Drug discovery; Small molecule; Computational biology; Bioinformatics; Biochemistry; Genetics","score_opus":0.0326419190105413,"score_gpt":0.3274791998505821,"score_spread":0.2948372808400408,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2799534791","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.02036921,0.9787899,0.000113712,0.000009518091,0.00020645202,0.00020213788,0.000011676253,0.0000064452724,0.00029090047],"genre_scores_gemma":[0.016145842,0.9784488,0.0046339324,0.0000040641335,0.000327915,0.000045967547,0.0001808596,0.00003233212,0.00018028296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976369,0.00010976405,0.0009090563,0.0006527403,0.0003133373,0.0003781873],"domain_scores_gemma":[0.99896204,0.000027270966,0.00062696397,0.00026453545,0.000044592856,0.00007458009],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010056983,0.00031330285,0.0009068985,0.00025711674,0.000053804917,0.000014088707,0.00069818785,0.00041733883,0.00029958488],"category_scores_gemma":[0.00015936955,0.00023948046,0.00036820013,0.0009058308,0.00055395794,0.0000048863167,0.00019295629,0.00016576872,0.0000022624554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017802387,0.00011949299,0.00001391061,0.0023370283,0.0000755476,0.0000013306776,0.000060917155,0.0000050089943,0.65234834,0.00027125992,0.00052523613,0.34422413],"study_design_scores_gemma":[0.0001526233,0.0003560399,2.7310455e-7,0.0034753878,0.00006785167,0.0000034559732,0.00004440214,0.00006448086,0.64981574,0.00013900797,0.34543827,0.00044245264],"about_ca_topic_score_codex":0.000028629313,"about_ca_topic_score_gemma":0.0000020832467,"teacher_disagreement_score":0.34491304,"about_ca_system_score_codex":0.000020281117,"about_ca_system_score_gemma":0.00012675984,"threshold_uncertainty_score":0.976573},"labels":[],"label_agreement":null},{"id":"W2800410051","doi":"10.1523/jneurosci.3113-17.2018","title":"Fear Memory Recall Potentiates Opiate Reward Sensitivity through Dissociable Dopamine D1 versus D4 Receptor-Dependent Memory Mechanisms in the Prefrontal Cortex","year":2018,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Psychology; Neuroscience; Ventral tegmental area; Prefrontal cortex; Dopamine; Recall; Fear conditioning; Dopaminergic; Amygdala; Cognition; Cognitive psychology","score_opus":0.020566615170585275,"score_gpt":0.26719978965408486,"score_spread":0.24663317448349958,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2800410051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9892425,0.00015570493,0.006921232,0.0003393689,0.002624202,0.0001645074,0.000010732885,0.0000064046963,0.00053536403],"genre_scores_gemma":[0.99656826,0.0002747905,0.0016817895,0.00054934353,0.0004816685,0.0000025259076,0.0000032591315,0.000018433022,0.00041990724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99790347,0.0003459221,0.00040976919,0.00037238942,0.0005853402,0.0003830858],"domain_scores_gemma":[0.99899364,0.00005006039,0.00039489043,0.00029045963,0.0001799091,0.00009106831],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015342144,0.00018967007,0.00024110448,0.000052090603,0.00023502388,0.000096757154,0.0004999708,0.00011531755,0.000039153863],"category_scores_gemma":[0.00034980412,0.00013611067,0.00014830678,0.00019539539,0.00018655171,0.000049815128,0.00016176996,0.0002844803,0.000006807158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027436716,0.00009151798,0.000022761915,0.0000048253823,0.000008823034,0.00005981733,0.00021111224,0.000104691135,0.99842715,0.000051168267,0.0001960639,0.0005477082],"study_design_scores_gemma":[0.0012254635,0.0025926507,0.0021862413,0.000045333327,0.000029799225,0.0002998969,0.00096268486,0.0002870095,0.9897924,0.00035736032,0.0019674487,0.00025370083],"about_ca_topic_score_codex":0.00004317866,"about_ca_topic_score_gemma":0.00005478284,"teacher_disagreement_score":0.008634732,"about_ca_system_score_codex":0.000044572207,"about_ca_system_score_gemma":0.00011837638,"threshold_uncertainty_score":0.5550432},"labels":[],"label_agreement":null},{"id":"W2801942411","doi":"10.1021/acschemneuro.8b00106","title":"PF-06827443 Displays Robust Allosteric Agonist and Positive Allosteric Modulator Activity in High Receptor Reserve and Native Systems","year":2018,"lang":"en","type":"article","venue":"ACS Chemical Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Neurosciences, Mental Health and Addiction; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institute of Mental Health; National Institute on Aging","keywords":"Agonist; Allosteric regulation; Allosteric modulator; Receptor; Pharmacology; Neuroscience; Muscarinic acetylcholine receptor; Chemistry; Biology; Biochemistry","score_opus":0.014938085293392096,"score_gpt":0.23807787264514008,"score_spread":0.22313978735174797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2801942411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99838156,0.00012218862,0.00062343274,0.00018393462,0.00030907296,0.00024648505,0.00004907207,0.000010984299,0.00007327462],"genre_scores_gemma":[0.99898803,0.000106911,0.00031308547,0.00025168882,0.00015592066,0.00002041256,0.000017434626,0.00002000508,0.00012649258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834394,0.00010025222,0.00019683124,0.0007931924,0.0002073619,0.00035844345],"domain_scores_gemma":[0.99937814,0.000038223563,0.00010009353,0.00023885065,0.00008089703,0.00016380877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021572821,0.00021456587,0.00022083308,0.00004478247,0.00014184363,0.00012314774,0.00024343494,0.00015377281,0.000004299671],"category_scores_gemma":[0.00020442436,0.00019410995,0.00002824308,0.00021936037,0.0004919961,0.000032685148,0.00042279792,0.00015256667,0.0000018965071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000110633875,0.000044794608,0.00053874153,0.000015873593,0.0000035555129,0.0000046090136,0.000059453625,0.0000119851875,0.998788,0.00009646766,0.00006099889,0.00026488563],"study_design_scores_gemma":[0.00039409377,0.00045928088,0.0025537598,0.00004180232,0.000005871544,0.000031623593,0.00003201641,0.0020826245,0.9938484,0.000040425206,0.00025864004,0.00025149866],"about_ca_topic_score_codex":0.00011170391,"about_ca_topic_score_gemma":0.000009655502,"teacher_disagreement_score":0.0049396376,"about_ca_system_score_codex":0.000026428153,"about_ca_system_score_gemma":0.00003397787,"threshold_uncertainty_score":0.79155743},"labels":[],"label_agreement":null},{"id":"W2802102272","doi":"10.1111/tra.12576","title":"7‐Ketocholesterol impairs phagocytosis and efferocytosis via dysregulation of phosphatidylinositol 4,5‐bisphosphate","year":2018,"lang":"en","type":"article","venue":"Traffic","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Efferocytosis; Biology; Phagocytosis; Cell biology; Phosphatidylinositol 4,5-bisphosphate; Phosphatidylinositol; Macrophage; Signal transduction; Biochemistry","score_opus":0.00607868148863291,"score_gpt":0.22869114121891235,"score_spread":0.22261245973027943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802102272","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99309605,0.00068390643,0.0057028006,0.000030010979,0.00016368691,0.00021224299,0.000008228012,0.000021902079,0.00008119157],"genre_scores_gemma":[0.9981983,0.000081771446,0.0013027965,0.00007712127,0.00017441691,0.000013029108,0.00003458241,0.000025318266,0.00009269761],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904627,0.00003838362,0.00026031522,0.0003158508,0.00013171922,0.00020749462],"domain_scores_gemma":[0.99945194,0.000011210254,0.00012004759,0.00023591326,0.00009488868,0.00008601942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014921615,0.00016579399,0.000195736,0.000040990795,0.00009014566,0.000020965512,0.0001196184,0.00014451474,0.000084268606],"category_scores_gemma":[0.000013761865,0.00015607814,0.00007692427,0.00008896095,0.00011717592,0.000007614381,0.00005029595,0.00004551401,0.000008787206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017025227,0.000049247865,0.0006550935,0.00002821668,0.000055402386,4.4611738e-7,0.00019003278,0.0001475672,0.96334255,0.00003163865,0.00013610016,0.035193466],"study_design_scores_gemma":[0.00074269966,0.000780372,0.0034464262,0.000028922508,0.000038351147,0.000007665904,0.000038513535,0.0021642367,0.99203086,0.000024648734,0.0005253135,0.00017197758],"about_ca_topic_score_codex":0.000010683119,"about_ca_topic_score_gemma":0.00001185577,"teacher_disagreement_score":0.035021488,"about_ca_system_score_codex":0.000008608572,"about_ca_system_score_gemma":0.00001942793,"threshold_uncertainty_score":0.6364682},"labels":[],"label_agreement":null},{"id":"W2802313658","doi":"10.1016/j.bcp.2018.04.021","title":"Angiotensin II cyclic analogs as tools to investigate AT1R biased signaling mechanisms","year":2018,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Functional selectivity; G protein-coupled receptor; Angiotensin II; Chemistry; Receptor; Signal transduction; Gq alpha subunit; G protein; Angiotensin receptor; Pharmacology; Biochemistry; Cell biology; Biology","score_opus":0.023165734802946623,"score_gpt":0.2960619317001075,"score_spread":0.2728961968971608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802313658","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900416,0.00032672513,0.0065165497,0.0012970451,0.000949911,0.00040486845,0.000028955163,0.000069368245,0.00036495595],"genre_scores_gemma":[0.97436434,0.000025773366,0.009786114,0.013407807,0.0017073015,0.000052801435,0.00015369833,0.0000589672,0.00044321883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99770576,0.00012542735,0.000410223,0.0008451313,0.000213009,0.00070047885],"domain_scores_gemma":[0.9987715,0.000035606703,0.000118724114,0.00032327863,0.00022324316,0.00052764633],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00033694846,0.0003507242,0.00033501573,0.00012074122,0.00027211188,0.000040983265,0.00044496448,0.00043317987,0.0013748358],"category_scores_gemma":[0.00022066309,0.0003489078,0.00018734,0.0003014689,0.00021550963,0.000008300943,0.00043215975,0.0001948885,0.00026596454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021954949,0.00007178439,0.0000054055954,0.0000057868883,0.000094604104,0.000011761873,0.000057624,0.000017050575,0.9033919,0.0002452274,0.095532596,0.00034673663],"study_design_scores_gemma":[0.00076066144,0.0012291757,0.000011793751,0.000016331564,0.00006440495,0.000031154756,0.000026666949,0.000095040756,0.95566785,0.0010998569,0.04056555,0.00043149048],"about_ca_topic_score_codex":0.00002648591,"about_ca_topic_score_gemma":0.000001239692,"teacher_disagreement_score":0.054967046,"about_ca_system_score_codex":0.0000418085,"about_ca_system_score_gemma":0.0001292385,"threshold_uncertainty_score":0.9998963},"labels":[],"label_agreement":null},{"id":"W2802745688","doi":"10.1016/j.schres.2018.04.028","title":"Improving cognitive training for schizophrenia using neuroplasticity enhancers: Lessons from decades of basic and clinical research","year":2018,"lang":"en","type":"review","venue":"Schizophrenia Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Atlantic Fellows Program; Natural Sciences and Engineering Research Council of Canada; Global Brain Health Institute","keywords":"Neuroplasticity; Schizophrenia (object-oriented programming); Cognition; Neuroscience; Cognitive training; Psychology; Biological neural network; Medicine; Psychiatry","score_opus":0.3635849843793102,"score_gpt":0.514653187729522,"score_spread":0.15106820335021176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802745688","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11124005,0.88017285,0.0050760666,0.000012778197,0.00049355853,0.0020325112,0.0009068014,0.000017842864,0.000047570626],"genre_scores_gemma":[0.022980968,0.9569269,0.015414214,0.000007817566,0.0037148676,0.00022880966,0.0004135869,0.0002257516,0.000087129985],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99172693,0.0027815856,0.0013027798,0.0019383192,0.0009823737,0.0012680034],"domain_scores_gemma":[0.9933227,0.0035956989,0.0004534589,0.00071368803,0.0014985069,0.00041596044],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00821265,0.0005589713,0.0017016388,0.00064756494,0.00076731277,0.00022503876,0.00086494803,0.0011694318,0.000065768356],"category_scores_gemma":[0.006781493,0.0005007173,0.0006503648,0.00070265186,0.0014734161,0.000019032035,0.0011205497,0.0019548777,0.000013593558],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021791388,0.00010852579,0.000006537238,0.002984481,0.0005537856,0.000008801758,0.00008574866,4.6036337e-7,0.027960135,0.00021227529,0.00014581309,0.9657543],"study_design_scores_gemma":[0.02951601,0.024706868,0.00013013692,0.1313253,0.006465154,0.00026605016,0.005351465,0.006798362,0.20817567,0.011184912,0.567321,0.008759061],"about_ca_topic_score_codex":0.00019331546,"about_ca_topic_score_gemma":0.00012886504,"teacher_disagreement_score":0.95699525,"about_ca_system_score_codex":0.0000767791,"about_ca_system_score_gemma":0.002817767,"threshold_uncertainty_score":0.9997445},"labels":[],"label_agreement":null},{"id":"W2802789425","doi":"10.5206/uwomj.v87i1.1910","title":"Biased mu-opioid receptor agonists confer analgesia with reduced side effects","year":2018,"lang":"en","type":"article","venue":"University of Western Ontario Medical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Opioid; Medicine; μ-opioid receptor; Analgesic; Pharmacology; Morphine; Side effect (computer science); Receptor; Depression (economics); Bioinformatics; Internal medicine; Biology","score_opus":0.006643744257532523,"score_gpt":0.20337273068707087,"score_spread":0.19672898642953834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802789425","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855429,0.000045722216,0.013082293,0.00020567537,0.00027086088,0.00008098083,0.0000021553863,0.000007058416,0.0007623411],"genre_scores_gemma":[0.99549204,0.000059775204,0.0022072433,0.00022320889,0.0003896643,9.9114864e-8,0.00002357705,0.000012837186,0.0015915778],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885046,0.00009161679,0.00015884913,0.00022811799,0.00042627804,0.0002446963],"domain_scores_gemma":[0.9990679,0.000016423875,0.00016401728,0.00016820378,0.00020231817,0.00038113334],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00027841172,0.00014230273,0.00023279674,0.00006027347,0.00019013575,0.000024075103,0.00032404173,0.00020513767,0.0011274666],"category_scores_gemma":[0.00004562573,0.00012452577,0.00010304514,0.000052417625,0.00025179557,0.000009809109,0.00007919214,0.00027971438,0.000017165008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018200377,0.00022698852,0.03383554,0.000043976932,0.0005030294,0.00042295034,0.001900046,0.000005561505,0.9477634,0.000040827737,0.0029387649,0.010498877],"study_design_scores_gemma":[0.008515725,0.007123605,0.036569476,0.00090137747,0.0002578318,0.0009509589,0.00096404244,0.00005693781,0.76645607,0.00007598,0.17731796,0.0008100278],"about_ca_topic_score_codex":0.0020808482,"about_ca_topic_score_gemma":0.018694608,"teacher_disagreement_score":0.18130732,"about_ca_system_score_codex":0.00006801812,"about_ca_system_score_gemma":0.0007584292,"threshold_uncertainty_score":0.99978566},"labels":[],"label_agreement":null},{"id":"W2803086497","doi":"","title":"Asymptotic analysis of equations for the buffered diffusion of intracellular Ca2","year":2001,"lang":"en","type":"article","venue":"W&M Publish (College of William & Mary)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Diffusion; Asymptotic analysis; Intracellular; Mathematics; Mathematical analysis; Applied mathematics; Physics; Chemistry; Thermodynamics","score_opus":0.01321671644923698,"score_gpt":0.2355598212354041,"score_spread":0.22234310478616712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803086497","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9063437,0.0010598305,0.090735,0.00031250494,0.00022343472,0.0005112744,0.00036238364,0.000006731693,0.00044516768],"genre_scores_gemma":[0.996701,0.00029143566,0.0014489604,0.000037680842,0.000092156086,0.000035582645,0.00025309352,0.000019222354,0.0011208948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99871135,0.00005790389,0.00051698537,0.00026330276,0.00024361571,0.0002068485],"domain_scores_gemma":[0.9985513,0.00013527907,0.00034825614,0.00049644866,0.0004098711,0.000058823975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045812211,0.00014621219,0.00038118105,0.00019996629,0.000083171544,0.000013654401,0.000371171,0.00016388668,0.00026735666],"category_scores_gemma":[0.00035869423,0.00011194467,0.0003989054,0.00071067794,0.00010759151,0.00001465067,0.00010077548,0.00005925956,3.1696047e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014279937,0.0002581027,0.0024957147,0.000055852222,0.0011521484,8.590397e-7,0.00008003093,0.001655336,0.98740494,0.002016312,0.0033434706,0.0013944089],"study_design_scores_gemma":[0.0025156261,0.001190577,0.011470265,0.00008224892,0.0029673914,0.0000032275777,0.0010768127,0.038593333,0.8981322,0.0012606577,0.04213842,0.00056922034],"about_ca_topic_score_codex":0.00009741526,"about_ca_topic_score_gemma":0.00009325227,"teacher_disagreement_score":0.0903573,"about_ca_system_score_codex":0.000012571081,"about_ca_system_score_gemma":0.0000836235,"threshold_uncertainty_score":0.4564971},"labels":[],"label_agreement":null},{"id":"W2804171243","doi":"10.1002/pep2.24078","title":"Equipotent enantiomers of cyclic opioid peptides at μ opioid receptor","year":2018,"lang":"en","type":"article","venue":"Peptide Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Enantiomer; Chemistry; Stereochemistry; Agonist; Affinities; Receptor; Peptide; Opioid receptor; Cyclic peptide; Biochemistry","score_opus":0.011636470315894534,"score_gpt":0.26060944619965304,"score_spread":0.2489729758837585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2804171243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941642,0.00023066223,0.0015908829,0.000042782995,0.0006030543,0.00013962755,0.000015415397,0.000014705173,0.0031986611],"genre_scores_gemma":[0.9905154,0.0001619567,0.0062125535,0.00012836205,0.00034096284,0.00000982014,0.000014885555,0.00001628183,0.002599774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982665,0.000027731192,0.00028194388,0.00055105553,0.00041442105,0.00045831574],"domain_scores_gemma":[0.9989551,0.000010770217,0.00015549123,0.00044712558,0.00026285325,0.00016867495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006550796,0.0001593545,0.00016419777,0.00011062646,0.00031478604,0.000036594614,0.0005732403,0.00008002305,0.00047162353],"category_scores_gemma":[0.00017876821,0.00013776205,0.00010531577,0.000377399,0.0010375879,0.00001571062,0.00039058446,0.000055125358,0.00011997041],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029509432,0.000022363382,0.00077673735,0.000013440714,0.000008338352,3.773191e-7,0.00017907859,0.00001005856,0.9950919,0.00021481028,0.0009943988,0.0026589916],"study_design_scores_gemma":[0.00016927274,0.00036274322,0.00096774905,0.000029244758,0.0000055756605,0.000007342248,0.00013623804,0.00008089001,0.9645597,0.00014459452,0.03335578,0.00018090352],"about_ca_topic_score_codex":0.00004619351,"about_ca_topic_score_gemma":0.0000199921,"teacher_disagreement_score":0.03236138,"about_ca_system_score_codex":0.000044215394,"about_ca_system_score_gemma":0.00016783069,"threshold_uncertainty_score":0.56177735},"labels":[],"label_agreement":null},{"id":"W2805364235","doi":"10.1016/j.exer.2018.06.006","title":"Expression of dopamine D2 and D3 receptors in the human retina revealed by positron emission tomography and targeted mass spectrometry","year":2018,"lang":"en","type":"article","venue":"Experimental Eye Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Mental Health; Scheme for Promotion of Academic and Research Collaboration; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Retina; Dopamine receptor D3; Dopamine receptor D2; Retinal; Positron emission tomography; Dopamine; Internal medicine; Human brain; Endocrinology; Schizophrenia (object-oriented programming); Chemistry; Medicine; Neuroscience; Biology; Ophthalmology; Psychiatry","score_opus":0.015796067558918617,"score_gpt":0.33715093425701564,"score_spread":0.32135486669809704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805364235","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934383,0.0056135496,0.00006328762,0.00005689743,0.000035447192,0.00024501013,0.0000043139567,0.0000039620786,0.00053922564],"genre_scores_gemma":[0.9984419,0.0002216051,0.0007848288,0.00001528547,0.00011239088,0.0000215232,0.000049247203,0.000015707832,0.00033755388],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985926,0.00032057567,0.00018979583,0.00033889763,0.00028467146,0.00027341672],"domain_scores_gemma":[0.99958396,0.00002259647,0.000047917427,0.0002145472,0.000053338863,0.0000776611],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000894877,0.0001157363,0.00013446528,0.00012791489,0.00019410723,0.000031310003,0.0001617757,0.00011801101,0.00012268955],"category_scores_gemma":[0.000037043577,0.00008416113,0.000034424786,0.00022319911,0.00025706197,0.0000071843097,0.0001622995,0.00016679819,6.784252e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012308158,0.0000853397,0.0047390275,0.000013649584,0.0000060629172,8.895402e-7,0.00033433482,2.6605438e-8,0.9927406,0.000018702896,0.0017473421,0.0001909689],"study_design_scores_gemma":[0.00046986094,0.0013781773,0.0007724755,0.00005351783,0.0000013810148,0.0000023231662,0.0017143533,0.0000064754754,0.99391294,0.00005168816,0.0015412086,0.0000955894],"about_ca_topic_score_codex":0.00005336262,"about_ca_topic_score_gemma":0.0000012702034,"teacher_disagreement_score":0.0053919447,"about_ca_system_score_codex":0.000015995978,"about_ca_system_score_gemma":0.000011171587,"threshold_uncertainty_score":0.34319913},"labels":[],"label_agreement":null},{"id":"W2805882949","doi":"10.1016/j.neuron.2018.05.027","title":"Muscarinic M1 Receptor Overstimulation Disrupts Working Memory Activity for Rules in Primate Prefrontal Cortex","year":2018,"lang":"en","type":"article","venue":"Neuron","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada First Research Excellence Fund","keywords":"Muscarinic acetylcholine receptor; Working memory; Prefrontal cortex; Stimulation; Neuroscience; Blockade; Psychology; Muscarinic acetylcholine receptor M1; Acetylcholine; Muscarinic acetylcholine receptor M4; Cognition; Receptor; Endocrinology; Internal medicine; Medicine","score_opus":0.019397020492414135,"score_gpt":0.2823966239460351,"score_spread":0.26299960345362094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2805882949","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942518,0.00004030224,0.0040753186,0.000027488246,0.00072767027,0.00031897856,0.000011104351,0.000015689062,0.00053169],"genre_scores_gemma":[0.9977453,0.000018697787,0.001101212,0.000062064144,0.00073940074,0.000025298343,0.0000698523,0.000026477835,0.00021172514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916583,0.000043401982,0.0001369325,0.00034633532,0.00008835287,0.00021913118],"domain_scores_gemma":[0.99964726,0.000018380837,0.000079686026,0.00018245849,0.000030358051,0.000041856645],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012972421,0.00012371193,0.0001172805,0.000033357013,0.00007849101,0.00002410754,0.00009615134,0.00011880985,0.000055066565],"category_scores_gemma":[0.00004612182,0.00012564026,0.00006780815,0.00003901291,0.00003207652,0.000007889389,0.0000641708,0.00006640813,0.0000097196325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002918363,0.000038876933,0.00054563774,0.000011982699,0.000007260606,3.4334326e-7,0.000052849322,0.00005726954,0.9829141,0.000020235791,0.00014885442,0.015910776],"study_design_scores_gemma":[0.0011127766,0.0008597067,0.03599547,0.0000371744,0.000014108972,0.0000025007748,0.000031742522,0.004430038,0.9447443,0.00009276258,0.012413012,0.00026643722],"about_ca_topic_score_codex":0.000017543558,"about_ca_topic_score_gemma":0.00004964031,"teacher_disagreement_score":0.038169805,"about_ca_system_score_codex":0.000025956599,"about_ca_system_score_gemma":0.000028271166,"threshold_uncertainty_score":0.51234615},"labels":[],"label_agreement":null},{"id":"W2806292364","doi":"10.1016/j.atherosclerosissup.2018.04.080","title":"Desmocollin 1 is Abundantly Expressed in Atherosclerosis and Impairs High-density Lipoprotein Biogenesis","year":2018,"lang":"en","type":"article","venue":"Atherosclerosis Supplements","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Monoclonal antibody; Cytokine; Immunology; Antibody; Biology","score_opus":0.013656693446700636,"score_gpt":0.24084646454985567,"score_spread":0.22718977110315502,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2806292364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975011,0.00008543395,0.0010783592,0.00018745066,0.00020263012,0.0006440938,0.00022878272,0.000038752612,0.000033401884],"genre_scores_gemma":[0.9925446,0.0005522042,0.0054469737,0.0005576303,0.00032422773,0.00016912173,0.00011919878,0.0000797653,0.00020629664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975909,0.0001294675,0.00048044094,0.00087273645,0.00029662668,0.00062984956],"domain_scores_gemma":[0.9989578,0.00001591112,0.0001603538,0.0005719404,0.0001130588,0.00018089404],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045050486,0.00038756747,0.0003477271,0.00010254283,0.00027572,0.00010407363,0.00032785273,0.00027626407,0.00082383904],"category_scores_gemma":[0.00003205933,0.00038349594,0.00012437758,0.00022881091,0.00017628212,0.000019370076,0.00029699854,0.000103148894,0.00003930926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007260711,0.00010959356,0.038951617,0.000013709312,0.00006107002,3.5572157e-7,0.00035081,0.0000016814146,0.95653844,0.000026036703,0.0012335605,0.002640535],"study_design_scores_gemma":[0.0017639968,0.00063630316,0.055988792,0.00006737379,0.00002454766,0.0000013913194,0.00018415936,0.00007144512,0.93613946,0.0001821462,0.00452321,0.0004171822],"about_ca_topic_score_codex":0.0021541363,"about_ca_topic_score_gemma":0.0009705476,"teacher_disagreement_score":0.020398973,"about_ca_system_score_codex":0.000044057902,"about_ca_system_score_gemma":0.000043989785,"threshold_uncertainty_score":0.9998617},"labels":[],"label_agreement":null},{"id":"W2807264878","doi":"10.1186/s13223-018-0266-5","title":"A bronchoprotective role for Rgs2 in a murine model of lipopolysaccharide-induced airways inflammation","year":2018,"lang":"en","type":"article","venue":"Allergy Asthma and Clinical Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; Lung Association, Alberta and NWT; University of Calgary","keywords":"Inflammation; Lipopolysaccharide; RGS2; Immunology; Medicine; Internal medicine; Receptor; G protein","score_opus":0.019212999853779625,"score_gpt":0.292636497802815,"score_spread":0.27342349794903537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807264878","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9808431,0.00026997668,0.018213153,0.00009902564,0.00014617837,0.00024165839,0.000004941794,0.0000069858497,0.00017495156],"genre_scores_gemma":[0.9970004,0.00029691687,0.0022051053,0.00006237309,0.00023919069,0.000055611927,0.000018166063,0.00001566543,0.00010655642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988305,0.000079100544,0.0004899565,0.00034012576,0.000049834725,0.00021047019],"domain_scores_gemma":[0.9993975,0.000045903504,0.00016665904,0.00020841451,0.00014272939,0.0000387859],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036835117,0.00012489154,0.00026074852,0.000051784693,0.000052799118,0.0000061842775,0.00013015,0.00036152077,0.00003301054],"category_scores_gemma":[0.0002170864,0.00011895482,0.000106260704,0.00004009588,0.0001429338,0.0000069841103,0.00011548076,0.00012600151,0.0000025588695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069754367,0.00007190136,0.00007252075,0.000004384057,0.0001240229,2.2978985e-7,0.000093545925,0.000044256398,0.9601201,0.002156887,0.000007962162,0.036606688],"study_design_scores_gemma":[0.002087832,0.0035378616,0.00084075803,0.000022710557,0.000007993084,0.000004335374,0.0002025108,0.013284071,0.973057,0.005060542,0.0017120903,0.00018234005],"about_ca_topic_score_codex":0.00009414604,"about_ca_topic_score_gemma":0.0003895469,"teacher_disagreement_score":0.036424346,"about_ca_system_score_codex":0.000007116939,"about_ca_system_score_gemma":0.00006324421,"threshold_uncertainty_score":0.48508367},"labels":[],"label_agreement":null},{"id":"W2807416930","doi":"10.3389/fnins.2018.00402","title":"Muscarinic Acetylcholine Type 1 Receptor Activity Constrains Neurite Outgrowth by Inhibiting Microtubule Polymerization and Mitochondrial Trafficking in Adult Sensory Neurons","year":2018,"lang":"en","type":"article","venue":"Frontiers in Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; Canadian Institutes of Health Research; Monash University; Florida State University","keywords":"Neurite; Cell biology; Muscarinic acetylcholine receptor; Neuroscience; Pirenzepine; Cytoskeleton; Biology; Muscarinic acetylcholine receptor M1; Chemistry; Receptor; Biochemistry; Cell; In vitro","score_opus":0.00923156476218876,"score_gpt":0.23622626933544208,"score_spread":0.22699470457325333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807416930","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9869042,0.00012457112,0.010584334,0.00011176628,0.0019412314,0.00021552395,0.000025273068,0.000015674887,0.000077409204],"genre_scores_gemma":[0.99653053,0.00022439606,0.002397278,0.0005145087,0.00020571939,0.000006585726,0.000014551088,0.000021912692,0.00008454184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984982,0.00013149998,0.00022522973,0.0006480394,0.00013689861,0.00036015676],"domain_scores_gemma":[0.9996014,0.000011344832,0.00010010871,0.00015408621,0.00004670701,0.00008634553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014344313,0.0001717299,0.00016980938,0.000116345305,0.00012778917,0.00006047574,0.00017252428,0.00012718712,0.000004647228],"category_scores_gemma":[0.00030169255,0.00018914482,0.00003212442,0.00033857493,0.0003273746,0.00002705975,0.0000991466,0.00019096091,7.1524073e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000763788,0.00004192011,0.0033445219,0.0000069734424,0.0000010729661,0.0000022236622,0.00012550874,0.0000196638,0.9918585,0.000006786861,0.00048853183,0.004027932],"study_design_scores_gemma":[0.000713752,0.00031224365,0.00092575303,0.00003126574,0.0000035578855,0.000012128887,0.00011927448,0.004420315,0.9918943,0.000006653935,0.0013285658,0.00023215638],"about_ca_topic_score_codex":0.00002433478,"about_ca_topic_score_gemma":0.000023345905,"teacher_disagreement_score":0.00962629,"about_ca_system_score_codex":0.000017147513,"about_ca_system_score_gemma":0.000062963154,"threshold_uncertainty_score":0.77131015},"labels":[],"label_agreement":null},{"id":"W2807910928","doi":"10.1101/349100","title":"High sensitivity mapping of cortical dopamine D2 receptor expressing neurons","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; University of Toronto","funders":"Canadian Institutes of Health Research; National Alliance for Research on Schizophrenia and Depression","keywords":"Neuroscience; Parvalbumin; Biology; Dopamine receptor D2; Context (archaeology); Dopamine; Prefrontal cortex; Receptor; Genetics; Cognition","score_opus":0.013686480263524588,"score_gpt":0.21758197406166022,"score_spread":0.20389549379813562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2807910928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9694831,0.0004351084,0.027578378,0.000054481567,0.0017186749,0.00039339907,0.00024226148,0.000087828856,0.000006773694],"genre_scores_gemma":[0.97692925,0.00017803039,0.021110898,0.000105229614,0.001487091,0.000036078836,0.000004014701,0.00014015673,0.000009281939],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968101,0.00036797638,0.0006898536,0.0011766789,0.0003683015,0.0005871354],"domain_scores_gemma":[0.99724036,0.00005167383,0.0005613321,0.0012855289,0.0005971922,0.00026393213],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00080291886,0.0005736038,0.00068455795,0.0001537815,0.0001838833,0.000105586405,0.00038323065,0.0007709249,0.00011483234],"category_scores_gemma":[0.00046200218,0.0006233844,0.0002616911,0.0002064838,0.00024926316,0.000011115469,0.00087632827,0.00059318665,0.000022351927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057010042,0.00010834944,0.0011920346,0.0002012047,0.00013288634,0.000016789143,0.0000046586574,0.00007830372,0.99771684,0.00011351918,0.00037430343,0.000004090237],"study_design_scores_gemma":[0.00035924016,0.00014091255,0.0073026153,0.0003617087,0.000067139445,5.8253537e-8,0.000004177013,0.00028695248,0.9879081,0.0000014833797,0.0029374892,0.00063009333],"about_ca_topic_score_codex":0.00004221361,"about_ca_topic_score_gemma":0.0000021933902,"teacher_disagreement_score":0.00980872,"about_ca_system_score_codex":0.000048800288,"about_ca_system_score_gemma":0.0003752349,"threshold_uncertainty_score":0.99962175},"labels":[],"label_agreement":null},{"id":"W2808524678","doi":"10.1038/s41586-018-0215-y","title":"Cryo-EM structure of human rhodopsin bound to an inhibitory G protein","year":2018,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":279,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health","keywords":"Rhodopsin; Arrestin; Transmembrane domain; G protein-coupled receptor; Receptor; Transmembrane protein; G protein; Protein subunit; Cell biology; Biology; Protein structure; Biochemistry; Biophysics; Chemistry; Gene","score_opus":0.006818177954139577,"score_gpt":0.27402036424051196,"score_spread":0.2672021862863724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808524678","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99882895,0.0002159038,0.00015601669,0.000041218373,0.00024714108,0.00020506707,0.000026416592,0.00001027301,0.00026904562],"genre_scores_gemma":[0.99519163,8.7913287e-7,0.0026792602,0.00043198103,0.0011161964,0.0000034601348,0.00006838294,0.000022518725,0.0004857159],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992173,0.000040712686,0.00013563353,0.00028843386,0.00014997051,0.0001679635],"domain_scores_gemma":[0.99937695,0.0000013874085,0.00006033347,0.00030631144,0.00016706147,0.00008797579],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009302851,0.00012455985,0.00012249082,0.000039963747,0.00009482014,0.000023922195,0.00019787684,0.00093462964,0.00021051457],"category_scores_gemma":[0.000035818586,0.000109662935,0.00004776204,0.000082279774,0.000042779175,0.0000040760174,0.00006716832,0.0003873329,0.0000033605097],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040612926,0.000019451547,0.000038306356,0.000014007297,0.0000102776985,7.522611e-7,0.000148873,0.0000019499114,0.9965821,0.00057515135,0.0016564167,0.0009121387],"study_design_scores_gemma":[0.00017763082,0.00096016575,0.00023651368,0.00002248492,0.0000052648224,0.0000026920115,0.000099507495,0.0000020062696,0.9903163,0.00088574836,0.0071526705,0.0001390684],"about_ca_topic_score_codex":0.0000082168735,"about_ca_topic_score_gemma":0.00012435787,"teacher_disagreement_score":0.0062658153,"about_ca_system_score_codex":0.000008903027,"about_ca_system_score_gemma":0.000049157035,"threshold_uncertainty_score":0.720872},"labels":[],"label_agreement":null},{"id":"W2808733627","doi":"10.1016/j.bmcl.2018.06.038","title":"Design and synthesis of bridged piperidine and piperazine isosteres","year":2018,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Servier; Université de Montréal","keywords":"Piperidine; Chemistry; Piperazine; Agonist; hERG; ADME; Stereochemistry; Morpholine; Chemical synthesis; Antagonist; Combinatorial chemistry; Receptor; In vitro; Organic chemistry; Biochemistry","score_opus":0.008997401335006476,"score_gpt":0.21544804815682364,"score_spread":0.20645064682181716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808733627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868685,0.0009014531,0.01113592,0.0008655057,0.00006491358,0.00009129972,0.000005678306,0.000010727531,0.00005601873],"genre_scores_gemma":[0.9968396,0.00022370092,0.0019288856,0.00042789843,0.0004991888,0.0000064537694,0.000010621401,0.000023449242,0.00004022168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990613,0.000034852885,0.00021533298,0.00034535956,0.0001400206,0.00020315211],"domain_scores_gemma":[0.99948984,0.000034938374,0.000092074115,0.00021041116,0.000056733057,0.00011602838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025143227,0.00017935838,0.00021666108,0.000019517436,0.00007095363,0.000013598907,0.00012389783,0.00011252158,0.00016328828],"category_scores_gemma":[0.00014608928,0.00015803409,0.000030973853,0.000060180537,0.00032394106,0.000003926212,0.00008337246,0.00007000808,0.0000017053675],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010376238,0.00001736304,0.00020405787,0.000070611946,0.000045552835,0.000003985426,0.000057772886,2.8300713e-7,0.99714315,0.000002005476,0.0007104849,0.0016409707],"study_design_scores_gemma":[0.0004636004,0.00013733105,0.0002733391,0.00006607168,0.000047155117,0.00009855838,0.00009203763,0.00004259757,0.99790347,0.0000067129577,0.0007030075,0.00016613101],"about_ca_topic_score_codex":0.000011194942,"about_ca_topic_score_gemma":5.362228e-7,"teacher_disagreement_score":0.009971096,"about_ca_system_score_codex":0.000009003619,"about_ca_system_score_gemma":0.000030907428,"threshold_uncertainty_score":0.64444435},"labels":[],"label_agreement":null},{"id":"W2808775590","doi":"10.1038/s41467-018-04883-5","title":"Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E","year":2018,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University Health Centre; Université de Montréal; Douglas Mental Health University Institute; McGill University","funders":"Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies; Fonds de Recherche du Québec - Santé; Canadian Health Services Research Foundation; Eli Lilly and Company","keywords":"EIF4E; Phosphorylation; Eukaryotic initiation factor; Synaptic plasticity; Long-term potentiation; Translation (biology); Neuroscience; Biology; Psychology; Endocrinology; Internal medicine; Medicine; Messenger RNA; Cell biology; Receptor; Biochemistry","score_opus":0.019831349993214533,"score_gpt":0.29131319657249055,"score_spread":0.27148184657927604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808775590","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7662785,0.008507947,0.22256726,0.00025243228,0.00039004826,0.00077305554,0.00030287512,0.00002496138,0.00090288656],"genre_scores_gemma":[0.9901755,0.0001316937,0.00879314,0.000057889767,0.00006982062,0.000028882705,0.00071799377,0.00001440767,0.000010687301],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991597,0.00010386073,0.00033004093,0.00014913508,0.00016876702,0.00008850137],"domain_scores_gemma":[0.9987125,0.00006260192,0.00021491542,0.0005719665,0.0004051184,0.00003294389],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014606956,0.000098085504,0.000130543,0.00006492685,0.000115826566,0.0000059891127,0.0003055718,0.0003140813,0.000116061245],"category_scores_gemma":[0.00003613915,0.000097547374,0.00008585835,0.00012502972,0.00011180391,0.0000139439335,0.000025846964,0.0001711637,0.0000020014156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007000071,0.00012268481,0.014677908,0.000008407559,0.00003457076,3.1141347e-8,0.0001728239,0.00004079395,0.9746596,0.00047341385,0.000038163536,0.009701606],"study_design_scores_gemma":[0.0011839388,0.00023232277,0.09988066,0.00003456951,0.000113720926,0.0000033491774,0.000038179933,0.005066605,0.890392,0.0002671681,0.0025916658,0.00019583986],"about_ca_topic_score_codex":0.000010700717,"about_ca_topic_score_gemma":0.00007719749,"teacher_disagreement_score":0.22389695,"about_ca_system_score_codex":0.000006951787,"about_ca_system_score_gemma":0.000061035615,"threshold_uncertainty_score":0.39778665},"labels":[],"label_agreement":null},{"id":"W2809189273","doi":"10.1073/pnas.1718489115","title":"Computational design of orthogonal membrane receptor-effector switches for rewiring signaling pathways","year":2018,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of General Medical Sciences; Leukemia and Lymphoma Society; National Institutes of Health; Cancer Prevention and Research Institute of Texas","keywords":"Effector; Receptor; Cell biology; Signal transduction; Intracellular; G protein-coupled receptor; Cell surface receptor; Biology; Computational biology; Biochemistry","score_opus":0.05391368435955663,"score_gpt":0.29366225169268956,"score_spread":0.23974856733313293,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809189273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956714,0.00009740869,0.00346464,0.00015106123,0.000040112824,0.00027850555,0.000036156536,0.0000044473873,0.00025628845],"genre_scores_gemma":[0.96186996,0.000008957061,0.037771083,0.00007635152,0.00022850995,0.0000143700545,0.0000015914449,0.0000064577466,0.000022742084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870974,0.000009528991,0.00033242154,0.00024234837,0.00056799187,0.00013796668],"domain_scores_gemma":[0.9988296,0.00011451085,0.00042632854,0.000008399194,0.00059330807,0.000027876871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016864552,0.00009540009,0.00015003215,0.0000769336,0.00017433257,0.0000123523605,0.0004391328,0.00009879358,0.000022499717],"category_scores_gemma":[0.0004778076,0.00006979734,0.00010324839,0.00023624749,0.0004582442,0.000021680313,0.00008291316,0.00005505009,4.444027e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000710961,0.000023339187,0.00032216485,0.00006192821,0.000025490292,4.8258575e-10,0.00006850146,0.0027705007,0.9853545,0.010953836,0.00015289274,0.00019577976],"study_design_scores_gemma":[0.00020914063,0.00027475817,0.0003368517,0.000083465,0.000009513124,0.0000019289473,0.000083616666,0.0036946244,0.97856593,0.016581358,0.000079503516,0.00007931763],"about_ca_topic_score_codex":8.6545396e-7,"about_ca_topic_score_gemma":1.4711686e-8,"teacher_disagreement_score":0.034306444,"about_ca_system_score_codex":0.000009540434,"about_ca_system_score_gemma":0.00006538771,"threshold_uncertainty_score":0.2846253},"labels":[],"label_agreement":null},{"id":"W2809797492","doi":"10.71781/28256","title":"Rôles non-canoniques des arrestines dans la signalisation et l’endocytose des récepteurs couplés aux protéines G","year":2017,"lang":"fr","type":"dissertation","venue":"Open MIND","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Canadian Space Agency; Genentech; Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Fondation ARC pour la Recherche sur le Cancer; McGill University; McGill University Health Centre; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; European Commission; Fonds de Recherche du Québec - Santé; Mitacs; Canada Research Chairs; Fonds National de la Recherche Luxembourg","keywords":"Chemistry; Humanities; Philosophy","score_opus":0.04980117612577399,"score_gpt":0.3608145524967136,"score_spread":0.3110133763709396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2809797492","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9594753,0.0018340631,0.003141837,0.000052593925,0.00056190445,0.0014464986,0.00016937472,0.000003981896,0.03331444],"genre_scores_gemma":[0.9442823,0.0017636414,0.02073717,0.000027995395,0.00049358455,0.00034330518,0.0044717994,0.00012939569,0.027750833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99730474,0.00031414386,0.00059829315,0.0009771948,0.00027965722,0.0005259959],"domain_scores_gemma":[0.99780524,0.00006850333,0.000712113,0.0006162087,0.0005903326,0.00020759378],"candidate_categories":["metaepi_narrow","scholarly_communication","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000847048,0.00068278785,0.00059380726,0.00008956518,0.00096292753,0.0012252018,0.0011575739,0.0007363002,0.001397175],"category_scores_gemma":[0.0004256061,0.0006637272,0.00024405021,0.000085628766,0.0005546437,0.000089546746,0.00021459773,0.00028858052,0.0000703379],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028383586,0.000166551,0.0019129721,0.0002213333,0.00018263896,0.000035838955,0.005232784,0.0001995045,0.89498395,0.00019903645,0.00013188423,0.096449666],"study_design_scores_gemma":[0.0006989484,0.00068419235,0.0016637038,0.0012526246,0.00020883275,0.000047025344,0.004730968,0.00024171858,0.96291673,0.00084908784,0.025894467,0.00081170344],"about_ca_topic_score_codex":0.0019381206,"about_ca_topic_score_gemma":0.008783653,"teacher_disagreement_score":0.09563796,"about_ca_system_score_codex":0.00006512891,"about_ca_system_score_gemma":0.0011826331,"threshold_uncertainty_score":0.99981165},"labels":[],"label_agreement":null},{"id":"W2810399886","doi":"10.1016/j.phrs.2018.06.027","title":"Label-free cell signaling pathway deconvolution of angiotensin type 1 receptor reveals time-resolved G-protein activity and distinct AngII and AngIIIIV responses","year":2018,"lang":"en","type":"article","venue":"Pharmacological Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Angiotensin II; Receptor; Endogeny; Signal transduction; Cell biology; HEK 293 cells; G protein-coupled receptor; Chemistry; Cell type; G protein; Functional selectivity; Biology; Cell; Biochemistry","score_opus":0.06984692852066239,"score_gpt":0.3616075175325956,"score_spread":0.29176058901193325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2810399886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99722135,0.0013903928,0.0003727794,0.00019833648,0.0000626775,0.00042919832,0.000060922233,0.000015973284,0.00024834607],"genre_scores_gemma":[0.99556065,0.00015685646,0.0027276075,0.000045851888,0.00029874023,0.000021400509,0.000020666217,0.000019931404,0.0011483016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99772847,0.0007654654,0.00021897987,0.0005118805,0.00031057253,0.00046461052],"domain_scores_gemma":[0.998749,0.00024182428,0.00008661464,0.0002299687,0.00048621025,0.00020638527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021963578,0.00016532082,0.0002362705,0.00009396835,0.0002628144,0.000038290396,0.00022930252,0.00022956723,0.0005092144],"category_scores_gemma":[0.0011341479,0.00013700667,0.000049722163,0.00024003413,0.00048146548,0.000011224566,0.0005046918,0.00024674524,0.000018729119],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018506546,0.00012873343,0.00023086558,0.000026385187,0.000033497654,0.000004664707,0.000032465094,4.861042e-7,0.99207944,0.000033020566,0.0018833952,0.0036963879],"study_design_scores_gemma":[0.0008272577,0.0022229927,0.00059201557,0.00002808759,0.000014034302,0.0000030315261,0.000023970231,0.0003058878,0.9927954,0.00034596614,0.0026793417,0.00016199793],"about_ca_topic_score_codex":0.00003170814,"about_ca_topic_score_gemma":0.000004257954,"teacher_disagreement_score":0.00353439,"about_ca_system_score_codex":0.00002497829,"about_ca_system_score_gemma":0.00009133337,"threshold_uncertainty_score":0.558697},"labels":[],"label_agreement":null},{"id":"W2835789356","doi":"10.1016/j.biopha.2018.06.157","title":"Pharmacological and toxicological activity of RSD921, a novel sodium channel blocker","year":2018,"lang":"en","type":"article","venue":"Biomedicine & Pharmacotherapy","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Xenon Pharmaceuticals (Canada); University of British Columbia","funders":"National Institutes of Health; National Institute of Neurological Disorders and Stroke; American Heart Association","keywords":"Sodium channel; Pharmacology; Sodium channel blocker; Ventricular fibrillation; Chemistry; Sodium; Effective refractory period; Blockade; Potassium channel; Medicine; Anesthesia; Internal medicine; Refractory period; Receptor","score_opus":0.0278434512407923,"score_gpt":0.32147133168973024,"score_spread":0.29362788044893795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2835789356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98870015,0.00082149083,0.008866255,0.0005771815,0.00047711655,0.00027540626,0.000021491993,0.000022659395,0.00023825154],"genre_scores_gemma":[0.9949504,0.0007708643,0.0009090614,0.0016060392,0.001469212,0.000024576006,0.000011972114,0.000021274045,0.00023660396],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988429,0.000056767112,0.00022220648,0.0004014316,0.00017996058,0.0002967135],"domain_scores_gemma":[0.9994569,0.000020154901,0.00011947699,0.00013393055,0.00010459424,0.00016497874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031790865,0.00020835322,0.00026802055,0.00007017995,0.00008649931,0.000008811377,0.00016958585,0.00017280252,0.0007620688],"category_scores_gemma":[0.000016729282,0.00015411906,0.00007752307,0.00014112036,0.0004147861,0.0000048854777,0.00007740615,0.000104721825,0.0000040350633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000659321,0.0003067787,0.00013072386,0.000011656048,0.00011548755,0.0000024285741,0.00007311768,3.5330004e-7,0.9870996,0.000020476755,0.0021541906,0.009425903],"study_design_scores_gemma":[0.00285698,0.002099825,0.0005650748,0.000011317354,0.00003961334,0.000023235047,0.000022861745,0.00052706536,0.96372,0.00002767039,0.029928036,0.00017831929],"about_ca_topic_score_codex":0.00001138432,"about_ca_topic_score_gemma":0.0000012166678,"teacher_disagreement_score":0.027773844,"about_ca_system_score_codex":0.000009667372,"about_ca_system_score_gemma":0.000039707335,"threshold_uncertainty_score":0.83441186},"labels":[],"label_agreement":null},{"id":"W285283909","doi":"10.1139/y08-050","title":"Sustained Ca<sup>2+</sup>signaling and delayed internalization associated with endothelin receptor heterodimers linked through a PDZ fingerThis article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin.","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"PDZ domain; Internalization; Förster resonance energy transfer; Receptor; HEK 293 cells; G protein-coupled receptor; Chemistry; Cell biology; Biophysics; Immunoprecipitation; Signal transduction; Yellow fluorescent protein; Biochemistry; Biology; Fluorescence; Gene","score_opus":0.011179881469699112,"score_gpt":0.23105996737115508,"score_spread":0.21988008590145597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W285283909","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991601,0.00018467077,0.00005746762,0.00024315013,0.000109498484,0.0001550974,0.00003672406,6.3962256e-7,0.000052663047],"genre_scores_gemma":[0.9987596,0.00025336805,0.00011767281,0.0005212504,0.00028955328,0.000004581464,0.000017432314,0.000009535391,0.00002695263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987722,0.00033233652,0.0004551101,0.00015782884,0.00007678715,0.00020571506],"domain_scores_gemma":[0.9992337,0.00008661103,0.00037720456,0.000056274926,0.00017669871,0.00006949008],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003792826,0.00011569739,0.00033101934,0.00014948848,0.000052595333,0.0000035725548,0.00011344339,0.00016352834,0.0015217721],"category_scores_gemma":[0.000105122555,0.00009133132,0.000051315892,0.00014229148,0.00019643838,0.00001818286,0.000011749127,0.00020547923,1.5248006e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011695604,0.00008330919,0.0028462377,0.000026661126,0.00019214005,0.0000074312584,0.004734831,0.0019451496,0.98814684,0.000015457977,0.0006661577,0.00016624005],"study_design_scores_gemma":[0.002730683,0.0019939607,0.0006485689,0.00007006118,0.000054376924,0.00002667329,0.0008422633,0.0006968219,0.9918891,0.00019132,0.0007509921,0.00010513583],"about_ca_topic_score_codex":0.0008291707,"about_ca_topic_score_gemma":0.0012705036,"teacher_disagreement_score":0.0038925675,"about_ca_system_score_codex":0.00003288174,"about_ca_system_score_gemma":0.00025117988,"threshold_uncertainty_score":0.99939096},"labels":[],"label_agreement":null},{"id":"W2884039411","doi":"10.1038/s41598-018-29876-8","title":"GRK2 knockdown in mice exacerbates kidney injury and alters renal mechanisms of blood pressure regulation","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Ottawa Hospital; University of Ottawa; Western University","funders":"Alexandria University; Canadian Institutes of Health Research; Alberta Innovates; Government of Canada","keywords":"Gene knockdown; Kidney; Blood pressure; Medicine; Renal injury; Acute kidney injury; Pharmacology; Internal medicine; Endocrinology; Bioinformatics; Biology; Gene; Biochemistry","score_opus":0.005633769641802375,"score_gpt":0.22239491286229426,"score_spread":0.2167611432204919,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884039411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956425,0.0003447589,0.0019005563,0.000039040027,0.0014871445,0.00020146082,0.000008020221,0.000009024279,0.0003675369],"genre_scores_gemma":[0.99582624,0.000009644161,0.0022846975,0.000030431524,0.00009589523,0.0000074549903,0.00007957474,0.00001174235,0.0016543008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865943,0.000044782184,0.00035254649,0.0005589401,0.00019874396,0.00018553715],"domain_scores_gemma":[0.9991762,0.0000037272207,0.00022729526,0.00035940786,0.00014013404,0.00009323144],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008714946,0.000109814486,0.00013326274,0.00009510316,0.000099951765,0.000054226257,0.000080572594,0.000115722396,0.00013310551],"category_scores_gemma":[0.00012179941,0.000101873076,0.000042719956,0.00015848018,0.00016540622,0.00001066824,0.00009053551,0.000045062116,0.0000010956833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024648452,0.000029674537,0.0003006099,0.000021506208,0.00002867963,0.000005173247,0.00009809508,0.000012985652,0.99665755,0.00013078844,0.0022916829,0.00039858115],"study_design_scores_gemma":[0.00013789223,0.00015974246,0.00018964906,0.000049665818,0.000042416355,0.000043120064,0.000026638421,0.00013204502,0.9842191,0.0068468344,0.008037911,0.00011498838],"about_ca_topic_score_codex":0.000028323422,"about_ca_topic_score_gemma":0.000012410584,"teacher_disagreement_score":0.012438478,"about_ca_system_score_codex":0.0000027138549,"about_ca_system_score_gemma":0.00008398433,"threshold_uncertainty_score":0.41542637},"labels":[],"label_agreement":null},{"id":"W2884315099","doi":"10.1007/s10620-018-5216-z","title":"Disruption of GPR35 Exacerbates Dextran Sulfate Sodium-Induced Colitis in Mice","year":2018,"lang":"en","type":"article","venue":"Digestive Diseases and Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Institute of Genetics; Wellcome Trust; American Heart Association","keywords":"Colitis; Inflammatory bowel disease; Ulcerative colitis; Intestinal mucosa; Western blot; Internal medicine; Medicine; Biology; Gene; Disease","score_opus":0.016933606323155243,"score_gpt":0.27668604139457664,"score_spread":0.25975243507142143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884315099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986204,0.0006552617,0.00014868572,0.000041275867,0.00008514731,0.00009087098,0.000028155395,0.0000036607526,0.00032652653],"genre_scores_gemma":[0.9995378,0.00016169857,0.0001311481,0.000034760622,0.00007903697,0.0000072007933,0.000012205719,0.0000039855818,0.000032158518],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99930197,0.000039021113,0.00012473833,0.00026332642,0.00010338434,0.00016756379],"domain_scores_gemma":[0.9997359,0.000017784241,0.00005413505,0.000058989986,0.000064427986,0.00006876566],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013496532,0.00008333953,0.00010013441,0.00004302648,0.000113965114,0.000030061832,0.00009943143,0.000040851573,0.000025772768],"category_scores_gemma":[0.00006183068,0.00006846411,0.000034948447,0.000121336845,0.00032604925,0.000011052578,0.000039596594,0.00002104712,0.0000011138641],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007998875,0.00004584354,0.19500342,0.000011579028,0.0000064845917,0.0000011859572,0.00014967915,0.0000067040046,0.80121,0.00069559,0.0000117477375,0.002777788],"study_design_scores_gemma":[0.00025299686,0.00060173846,0.592636,0.000039228653,0.000009615605,0.0000018511585,0.0006363095,0.00028319878,0.4046999,0.0005927571,0.0001194411,0.00012697642],"about_ca_topic_score_codex":0.00013137425,"about_ca_topic_score_gemma":0.000031522555,"teacher_disagreement_score":0.39763257,"about_ca_system_score_codex":0.000004163824,"about_ca_system_score_gemma":0.000049879887,"threshold_uncertainty_score":0.27918854},"labels":[],"label_agreement":null},{"id":"W2884874610","doi":"10.1021/acs.jmedchem.8b00566","title":"Discovery of a Potent, Selective, and Brain-Penetrant Small Molecule that Activates the Orphan Receptor GPR88 and Reduces Alcohol Intake","year":2018,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute on Alcohol Abuse and Alcoholism; U.S. Food and Drug Administration","keywords":"Chemistry; Pharmacology; Agonist; Penetrant (biochemical); Orphan receptor; G protein-coupled receptor; Self-administration; Nasal administration; Knockout mouse; Partial agonist; Receptor; Alcohol; Brain stimulation reward; Biochemistry; Nucleus accumbens; Medicine","score_opus":0.014107307743822977,"score_gpt":0.24732270592097041,"score_spread":0.23321539817714743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884874610","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958388,0.0025323762,0.0004915493,0.0006579397,0.000111158435,0.00006600097,0.0000062753406,0.0000018685123,0.00029399735],"genre_scores_gemma":[0.997675,0.00077168323,0.0004140837,0.00017484168,0.0007237732,0.0000018092912,0.000005306118,0.000015644518,0.00021787093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990527,0.000049087856,0.00029850242,0.000199914,0.0002256637,0.00017412004],"domain_scores_gemma":[0.99895006,0.000054587017,0.0005834601,0.00013273528,0.000178835,0.000100290374],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051167654,0.00015912953,0.00024507297,0.000025741097,0.00008419091,0.00003100664,0.00020282161,0.00012553496,0.000026997846],"category_scores_gemma":[0.00028987878,0.000101051315,0.00008031464,0.00006572288,0.0002952402,0.000012483274,0.0000741675,0.00021548156,1.6414172e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036358836,0.000032905755,0.0005262752,0.000050118902,0.00013462137,0.0000052117207,0.00018565994,5.601093e-7,0.9958992,0.0000036713984,0.0007857629,0.0020124041],"study_design_scores_gemma":[0.0007215155,0.00064232317,0.00045712956,0.00016605375,0.00005582074,0.00041950407,0.0010523481,0.000009463145,0.995486,0.00007238439,0.00080569036,0.00011172249],"about_ca_topic_score_codex":0.000012894695,"about_ca_topic_score_gemma":0.0000023912435,"teacher_disagreement_score":0.0019006816,"about_ca_system_score_codex":0.000012834598,"about_ca_system_score_gemma":0.00011011736,"threshold_uncertainty_score":0.4120753},"labels":[],"label_agreement":null},{"id":"W2886037034","doi":"10.1038/s42003-018-0106-7","title":"Expression map of 78 brain-expressed mouse orphan GPCRs provides a translational resource for neuropsychiatric research","year":2018,"lang":"en","type":"article","venue":"Communications Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University; Douglas Mental Health University Institute","funders":"Fonds de Recherche du Québec - Santé; Jewish General Hospital; Centre National de la Recherche Scientifique; Conseil Régional d'Alsace; Fonds Unique Interministériel; Université de Strasbourg; Institut National de la Santé et de la Recherche Médicale","keywords":"Human brain; Computational biology; Brain function; Biology; Neuroscience; G protein-coupled receptor; Bioinformatics; Receptor; Genetics","score_opus":0.06821610873802673,"score_gpt":0.3733859241402986,"score_spread":0.30516981540227184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886037034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9116577,0.004868284,0.06807855,0.010617042,0.00027382086,0.0018100411,0.0003452477,0.000058557667,0.0022907539],"genre_scores_gemma":[0.969014,0.00010960316,0.029062212,0.0001741154,0.00023414452,0.000155248,0.00062058587,0.000025549503,0.0006045361],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985689,0.00050228,0.00029957306,0.0003017334,0.00008451931,0.00024300067],"domain_scores_gemma":[0.99795455,0.00027092674,0.00011492761,0.0012145317,0.00038951702,0.000055535653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00073467265,0.00010668007,0.00014057965,0.00013228528,0.00036828482,0.000013060368,0.0009124358,0.00019090885,0.000054095053],"category_scores_gemma":[0.00025202206,0.00009734726,0.00009013442,0.00014432213,0.00048977777,0.0000045473134,0.0002802598,0.00013287789,0.0000076071447],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015408694,0.0000979161,0.00025926105,0.00001756595,0.00001724532,1.9610958e-8,0.00013332372,0.0000058295145,0.9868875,0.0036846688,0.006901662,0.001840935],"study_design_scores_gemma":[0.0004639585,0.0006589725,0.000049186805,0.000013046858,0.0000061227993,0.0000011660137,0.00010913336,0.0003670939,0.63035893,0.002553849,0.3653171,0.00010141799],"about_ca_topic_score_codex":0.000012037318,"about_ca_topic_score_gemma":0.000023609078,"teacher_disagreement_score":0.35841542,"about_ca_system_score_codex":0.000006149703,"about_ca_system_score_gemma":0.00010003837,"threshold_uncertainty_score":0.39697063},"labels":[],"label_agreement":null},{"id":"W2886886952","doi":"10.1007/s12035-018-1253-z","title":"Alternative Splicing of the Delta-Opioid Receptor Gene Suggests Existence of New Functional Isoforms","year":2018,"lang":"en","type":"article","venue":"Molecular Neurobiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University and Génome Québec Innovation Centre; McGill University","funders":"Canadian Institutes of Health Research; U.S. Department of Health and Human Services","keywords":"Exon; Alternative splicing; Gene isoform; Biology; RNA splicing; Gene; Genetics; Computational biology; RNA","score_opus":0.014201185976108078,"score_gpt":0.23477251898852014,"score_spread":0.22057133301241205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886886952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9707811,0.00012377351,0.027778143,0.0000866039,0.0007539719,0.00016821858,0.000023967732,0.00000592111,0.00027832758],"genre_scores_gemma":[0.9969334,0.000047456222,0.0018604306,0.00047602857,0.00026642255,0.0000056907634,0.00005134969,0.000023014822,0.0003362266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988588,0.00010201075,0.0003232064,0.00036244857,0.000116967414,0.0002365296],"domain_scores_gemma":[0.9990733,0.000014700498,0.00025274753,0.0004166093,0.00018548613,0.00005714852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013861495,0.00016461196,0.00021453388,0.00004182289,0.0000664295,0.000004821631,0.00034744747,0.00014814088,0.00012847786],"category_scores_gemma":[0.00009234341,0.000120709105,0.00017506856,0.00012788632,0.00024378183,0.0000033147949,0.00022789273,0.00009753801,0.000007430341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000846723,0.00002517401,0.00048723354,0.000008326616,0.000048856946,7.098829e-7,0.00005772947,0.0001845643,0.99757224,0.0005836221,0.00046004023,0.00048681305],"study_design_scores_gemma":[0.00033719873,0.00065359223,0.0007041367,0.000015999627,0.000016314289,0.000021025917,0.000015314725,0.000047681024,0.99432886,0.00063350657,0.0031078572,0.00011851755],"about_ca_topic_score_codex":0.000090627786,"about_ca_topic_score_gemma":0.000014691057,"teacher_disagreement_score":0.026152307,"about_ca_system_score_codex":0.000008703953,"about_ca_system_score_gemma":0.000109702065,"threshold_uncertainty_score":0.49223745},"labels":[],"label_agreement":null},{"id":"W2886891820","doi":"10.1016/j.bpj.2018.08.001","title":"Ligand-Induced Coupling between Oligomers of the M2 Receptor and the Gi1 Protein in Live Cells","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"G protein-coupled receptor; Receptor; Heterotrimeric G protein; G protein; Chinese hamster ovary cell; 5-HT5A receptor; Agonist; Ligand (biochemistry); Chemistry; mCherry; Biology; Biophysics; Green fluorescent protein; Cell biology; Biochemistry","score_opus":0.010831749756722324,"score_gpt":0.23340227877912798,"score_spread":0.22257052902240565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886891820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991628,0.00004312978,0.00014855144,0.00024890597,0.0001700232,0.00017880337,0.000003660453,0.0000016874502,0.000042424195],"genre_scores_gemma":[0.9986035,0.00003754606,0.00018898382,0.000055095603,0.0010536644,0.0000045243182,9.497166e-7,0.00001131975,0.000044380504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992322,0.000072918076,0.00022410558,0.00014573918,0.00015164654,0.00017344704],"domain_scores_gemma":[0.99954563,0.000022825132,0.00015390715,0.0001435934,0.00007585039,0.00005819576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035467633,0.00010418923,0.00016839748,0.000018792345,0.00013681388,0.000032675667,0.00022085795,0.00009354267,0.000015469286],"category_scores_gemma":[0.000044991448,0.000055820205,0.00010873602,0.00008729927,0.00020647142,0.0000040734044,0.00010114927,0.00020513847,0.0000048388074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000087231616,0.000018316357,0.00016647522,0.000004536368,0.000028248258,2.9808015e-7,0.00016794723,0.0000033894748,0.9987949,0.00009841619,0.000033115673,0.0005970829],"study_design_scores_gemma":[0.0006992437,0.00022755562,0.0004095491,0.00005492565,0.000013499976,0.000002807855,0.00015741709,0.000117702,0.9978144,0.00015407098,0.0002692266,0.00007957334],"about_ca_topic_score_codex":0.000019206855,"about_ca_topic_score_gemma":0.0000027449512,"teacher_disagreement_score":0.0009805145,"about_ca_system_score_codex":0.0000094268535,"about_ca_system_score_gemma":0.000047135934,"threshold_uncertainty_score":0.22762819},"labels":[],"label_agreement":null},{"id":"W2886974230","doi":"10.1007/978-1-4939-8576-0_17","title":"Conformational Profiling of the 5-HT2A Receptor Using FlAsH BRET","year":2018,"lang":"en","type":"book-chapter","venue":"Neuromethods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Functional selectivity; Receptor; Signal transduction; Agonist; Förster resonance energy transfer; HEK 293 cells; Chemistry; Biophysics; G protein-coupled receptor; Cell biology; Effector; Intracellular; Biochemistry; Biology; Fluorescence","score_opus":0.03913137424425669,"score_gpt":0.2911154610532309,"score_spread":0.2519840868089742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886974230","genre_codex":"other","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21811081,0.001983637,0.13550384,0.0001932701,0.016335301,0.0029996585,0.0012509238,0.00010077074,0.6235218],"genre_scores_gemma":[0.008759504,0.00047072736,0.5092326,0.0013223931,0.004443753,0.000024653571,0.0006291439,0.00041738484,0.47469983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987247,0.00009368952,0.00040750077,0.00032291366,0.0002746681,0.00017654024],"domain_scores_gemma":[0.9988331,0.000029157205,0.00041452597,0.0004600575,0.00021133367,0.00005183148],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00044783176,0.00025102356,0.00027291628,0.000060648534,0.00009987854,0.00002119156,0.00034675206,0.00040778585,0.0011656381],"category_scores_gemma":[0.00011082726,0.0001979028,0.0002651949,0.00003499014,0.0001439636,0.000003809978,0.00024092248,0.00023191178,0.000016851109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026829735,0.0000055408605,0.0000066957,0.000052404477,0.00005402271,2.9536605e-7,0.00002476992,0.00002755615,0.9918567,0.005241182,0.0013908801,0.0013131201],"study_design_scores_gemma":[0.00014572244,0.00014228828,0.0000037571463,0.00008410927,0.000039145274,0.000018029332,0.000006252483,0.00017834679,0.768254,0.002168295,0.22874685,0.00021324273],"about_ca_topic_score_codex":0.0000013239545,"about_ca_topic_score_gemma":5.715443e-7,"teacher_disagreement_score":0.37372878,"about_ca_system_score_codex":0.000014971156,"about_ca_system_score_gemma":0.00016045514,"threshold_uncertainty_score":0.99974746},"labels":[],"label_agreement":null},{"id":"W2887114221","doi":"10.1038/s41416-018-0200-0","title":"Identification of beta-arrestin-1 as a diagnostic biomarker in lung cancer","year":2018,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal; Institute for Research in Immunology and Cancer; Université de Montréal","funders":"Integrated BioBank of Luxembourg","keywords":"Lung cancer; Biomarker; Medicine; Tissue microarray; Immunohistochemistry; Oncology; Cancer; Adenocarcinoma; Pathology; Internal medicine; Biology","score_opus":0.009776238330703763,"score_gpt":0.3011209812806427,"score_spread":0.29134474294993895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887114221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97082573,0.027359648,0.0009410426,0.000085348445,0.0006058988,0.000079393794,0.000022147526,0.0000011806167,0.00007960666],"genre_scores_gemma":[0.9931896,0.00601862,0.00011018027,0.000083088904,0.00040544386,0.00001306659,0.000003104253,0.000013374885,0.00016357042],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907243,0.000049462997,0.00044854532,0.00012754078,0.00016964164,0.00013239545],"domain_scores_gemma":[0.9991425,0.00001983571,0.0003613308,0.00008105854,0.00034221617,0.000053025153],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033964717,0.000069254216,0.00015976401,0.000052807794,0.000032720538,0.000027584485,0.00014533891,0.00007633866,0.00042139215],"category_scores_gemma":[0.00022135011,0.00007603984,0.00008491963,0.00010183199,0.000060978175,0.000009193987,0.000025084037,0.0000750503,0.0000010596825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006909032,0.00003763951,0.010604734,0.000027862854,0.000084412626,0.000022918355,0.00004818165,0.00009204654,0.9432522,0.000010469021,0.0018693159,0.04388113],"study_design_scores_gemma":[0.0008169637,0.00015231395,0.061419193,0.00060922874,0.00007647509,0.00014765147,0.000047248104,0.00013876862,0.9300146,0.00012618006,0.0062994757,0.00015190023],"about_ca_topic_score_codex":0.00067745324,"about_ca_topic_score_gemma":0.0010903243,"teacher_disagreement_score":0.05081446,"about_ca_system_score_codex":0.000028364448,"about_ca_system_score_gemma":0.0001742647,"threshold_uncertainty_score":0.46139485},"labels":[],"label_agreement":null},{"id":"W2887448192","doi":"10.1007/s10616-018-0231-7","title":"A luciferase complementation assay system using transferable mouse artificial chromosomes to monitor protein–protein interactions mediated by G protein-coupled receptors","year":2018,"lang":"en","type":"article","venue":"Cytotechnology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canada Excellence Research Chairs, Government of Canada; Ministry of Education, Culture, Sports, Science and Technology","keywords":"HEK 293 cells; G protein-coupled receptor; Luciferase; Receptor; Transfection; Complementation; Molecular biology; Biology; Chemistry; Cell biology; Cell culture; Gene; Biochemistry; Genetics; Mutant","score_opus":0.016580331253057193,"score_gpt":0.2675325185339612,"score_spread":0.250952187280904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887448192","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8463695,0.000049231337,0.1509229,0.00031602423,0.00030033733,0.0017376895,0.00009985458,0.00017921034,0.000025241752],"genre_scores_gemma":[0.9907337,0.0000024543297,0.0073835473,0.000057739282,0.00039655314,0.0006189245,0.00030176618,0.00007065863,0.00043469205],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978779,0.00016164154,0.0005386441,0.0006774011,0.00021175895,0.0005326798],"domain_scores_gemma":[0.9989825,0.000009905395,0.000161962,0.0004534849,0.0002466798,0.00014548769],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034602964,0.0003204068,0.00033454166,0.00021394818,0.00039049503,0.000066446424,0.0003199681,0.00042968188,0.00029382674],"category_scores_gemma":[0.00013721386,0.00032879142,0.00009984141,0.00035300144,0.00013702484,0.00001885304,0.00009951628,0.00025172747,0.00007610115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019490073,0.00009448511,0.000007378767,0.000037547565,0.00007620537,0.0000030818196,0.0000778883,0.00002986177,0.9975822,0.00037359586,0.00020710053,0.0013157431],"study_design_scores_gemma":[0.00051293994,0.00088054733,7.186019e-7,0.00009509515,0.000021041513,0.000013934108,0.0006795652,0.0023952338,0.9904773,0.00008027508,0.004487853,0.00035549366],"about_ca_topic_score_codex":0.00019383128,"about_ca_topic_score_gemma":0.000109548666,"teacher_disagreement_score":0.14436415,"about_ca_system_score_codex":0.00016351901,"about_ca_system_score_gemma":0.00007874914,"threshold_uncertainty_score":0.99991643},"labels":[],"label_agreement":null},{"id":"W2887604271","doi":"10.1038/s42003-018-0101-z","title":"Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes","year":2018,"lang":"en","type":"article","venue":"Communications Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Bioluminescence; Transducer; Biosensor; G protein-coupled receptor; Förster resonance energy transfer; Energy transfer; Biophysics; Ligand (biochemistry); Resonance (particle physics); Chemistry; Receptor; Biology; Physics; Fluorescence; Biochemistry; Chemical physics; Acoustics","score_opus":0.026753560521144637,"score_gpt":0.27321084384312194,"score_spread":0.2464572833219773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887604271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98635024,0.0044145016,0.007943486,0.00071385416,0.00013053775,0.000107376916,0.00009589181,0.000018308083,0.00022583123],"genre_scores_gemma":[0.9921299,0.0032189053,0.004035203,0.00013185582,0.00010185573,0.000029319319,0.00031312823,0.0000109328,0.000028883003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992799,0.00010035615,0.00022571014,0.00018500311,0.000047199515,0.00016183719],"domain_scores_gemma":[0.9991052,0.00006300217,0.000061007897,0.00054031605,0.00018004977,0.00005041637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016096399,0.00011860084,0.00014839291,0.000069550515,0.00014798659,0.000008032334,0.00038822778,0.00017504864,0.000016093036],"category_scores_gemma":[0.000047169477,0.000112485104,0.000040716586,0.00011430443,0.0005274258,0.000004333602,0.000064272404,0.00006005107,0.0000017289772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039371236,0.000033617696,0.0024812561,0.000007952485,0.000018400871,4.985297e-8,0.000098764314,8.458076e-7,0.9910328,0.0015515123,0.000017747725,0.0047176923],"study_design_scores_gemma":[0.00038051562,0.00037284946,0.0009727987,0.000030533753,0.0000093743565,0.0000027266158,0.00008846546,0.00056635425,0.96414775,0.00005627978,0.033241916,0.00013042448],"about_ca_topic_score_codex":0.000038914834,"about_ca_topic_score_gemma":0.00008169023,"teacher_disagreement_score":0.03322417,"about_ca_system_score_codex":0.0000058629234,"about_ca_system_score_gemma":0.000052943513,"threshold_uncertainty_score":0.45870093},"labels":[],"label_agreement":null},{"id":"W2887605000","doi":"10.1016/j.jmb.2018.08.009","title":"A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin","year":2018,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Argonne National Laboratory; National Institute of General Medical Sciences; Office of Science; National Cancer Institute; National Institutes of Health; University of Toronto; Canada Excellence Research Chairs, Government of Canada; Industrial Macromolecular Crystallography Association Collaborative Access Team; Compute Canada","keywords":"Rhodopsin; Arrestin; G protein-coupled receptor; Biophysics; Biology; Squid; Chemistry; Receptor; Biochemistry","score_opus":0.014995472924585576,"score_gpt":0.2782647827100122,"score_spread":0.2632693097854266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887605000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90962607,0.0010260639,0.08850132,0.00032488463,0.00025779466,0.00011259293,0.0000017675235,0.0000033389813,0.0001461854],"genre_scores_gemma":[0.97166276,0.000073884374,0.027396547,0.00040826786,0.00037426664,0.000002210003,0.00001343013,0.00002230332,0.000046331766],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989643,0.000087312415,0.0003817254,0.0002569819,0.00009616512,0.00021351415],"domain_scores_gemma":[0.99919796,0.00001728129,0.00031640276,0.00015663188,0.0001818185,0.00012993177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030119694,0.00017501251,0.00025834702,0.00015279085,0.000044679553,0.000024956853,0.00016276247,0.00020617238,0.000029529208],"category_scores_gemma":[0.00019098961,0.00013362913,0.000066721084,0.000119101045,0.000115147894,0.0000114778395,0.0000758632,0.00021560727,0.0000019143085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006672099,0.000049697563,0.0016413202,0.000008481357,0.00006254119,0.000027250242,0.00017586829,0.000024945692,0.9926497,0.0002250955,0.000111228386,0.0043566893],"study_design_scores_gemma":[0.0016724041,0.0040456313,0.0006062891,0.000109197295,0.000031110347,0.0007130104,0.00013723948,0.0000840818,0.9668378,0.0005381596,0.025001986,0.0002230945],"about_ca_topic_score_codex":0.00016861221,"about_ca_topic_score_gemma":0.00022451418,"teacher_disagreement_score":0.062036708,"about_ca_system_score_codex":0.000027244108,"about_ca_system_score_gemma":0.00024989154,"threshold_uncertainty_score":0.5449238},"labels":[],"label_agreement":null},{"id":"W2888834459","doi":"10.3389/fnmol.2018.00286","title":"Characterization of the Zebrafish Glycine Receptor Family Reveals Insights Into Glycine Receptor Structure Function and Stoichiometry","year":2018,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Epilepsiatutkimussäätiö; Japan Epilepsy Research Foundation; Japan Society for the Promotion of Science; University of the Sunshine Coast; Ministry of Education, Culture, Sports, Science and Technology; Institute of Genetics; Naito Foundation","keywords":"Glycine receptor; Picrotoxin; Homomeric; Zebrafish; Biology; Protein subunit; Receptor; Glycine; Transmembrane domain; Xenopus; Strychnine; Transmembrane protein; Cell biology; Gephyrin; Cys-loop receptors; Biochemistry; GABAA receptor; Amino acid; Gene; Acetylcholine receptor","score_opus":0.004446719500060606,"score_gpt":0.2015782793630781,"score_spread":0.1971315598630175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888834459","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89053816,0.00033454967,0.1060654,0.00008126552,0.0026722117,0.00026218742,0.000016836522,0.000008333681,0.00002104689],"genre_scores_gemma":[0.99457735,0.00013875145,0.0038803038,0.0010651586,0.00015406712,0.0000069910284,0.000052892774,0.000024517421,0.0000999712],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984743,0.00015452906,0.0002994494,0.00055770425,0.0002845738,0.00022945878],"domain_scores_gemma":[0.9992229,0.0000037829134,0.00019884242,0.00040004193,0.00010009979,0.000074370495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001682305,0.00019141464,0.00020592079,0.0001517099,0.00016057616,0.000036898855,0.00034862166,0.00015975855,0.000012563569],"category_scores_gemma":[0.00016164094,0.00015185715,0.000047315058,0.00068895164,0.00032957637,0.00002299822,0.00018171758,0.00013899605,6.2577874e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008943639,0.000022251917,0.0020457658,0.000017184402,0.0000053922686,4.9215254e-7,0.00007565038,0.000012020045,0.9961614,0.000100608224,0.00040877517,0.0010610052],"study_design_scores_gemma":[0.0003921729,0.00047692587,0.012097149,0.000035859062,0.0000107801825,0.0000023281468,0.000052477466,0.000286423,0.97666174,0.00051017845,0.009296727,0.00017723028],"about_ca_topic_score_codex":0.000008372953,"about_ca_topic_score_gemma":0.0000034780887,"teacher_disagreement_score":0.10403918,"about_ca_system_score_codex":0.000019651252,"about_ca_system_score_gemma":0.000050181552,"threshold_uncertainty_score":0.6192555},"labels":[],"label_agreement":null},{"id":"W2889009582","doi":"10.3389/fphar.2018.00953","title":"Behavioral Effects of a Potential Novel TAAR1 Antagonist","year":2018,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Toronto","funders":"Canadian Institutes of Health Research; H. Lundbeck A/S; Russian Science Foundation; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Antagonist; Pharmacology; Medicine; Neuroscience; Chemistry; Biology; Internal medicine; Receptor","score_opus":0.006367138382531011,"score_gpt":0.27465074043439736,"score_spread":0.26828360205186635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889009582","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9340482,0.0004953595,0.059840474,0.00004179456,0.005223116,0.00020321054,0.000010852413,0.000006996824,0.0001299988],"genre_scores_gemma":[0.9884247,0.000082075974,0.010483907,0.00019708875,0.00057141524,0.000022748014,0.000026710746,0.000017968623,0.00017338632],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915004,0.00005330373,0.00019819562,0.00026324202,0.00007631386,0.00025889062],"domain_scores_gemma":[0.9996853,0.0000038847957,0.00008150398,0.00011697902,0.000056596713,0.000055737568],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011273116,0.00012044807,0.00019202892,0.000082233215,0.000045904828,0.0000053879057,0.00018687357,0.0001630105,0.000104752544],"category_scores_gemma":[0.000008769913,0.00012493494,0.00007210693,0.000087457476,0.00019153817,0.0000032850073,0.00008485056,0.00008862438,0.00000280772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021760701,0.00019842156,0.0010935972,0.000019602885,0.000043568572,0.000010720828,0.00005678389,0.000015002592,0.9837806,0.000017916194,0.012432902,0.002113248],"study_design_scores_gemma":[0.0016459989,0.0007555631,0.00028104417,0.0000067540527,0.00004472442,0.000009720479,0.00004304851,0.00036026098,0.98402375,0.00004883315,0.012649531,0.00013079886],"about_ca_topic_score_codex":0.000024499437,"about_ca_topic_score_gemma":0.0000043648797,"teacher_disagreement_score":0.0543765,"about_ca_system_score_codex":0.000016467244,"about_ca_system_score_gemma":0.000050999603,"threshold_uncertainty_score":0.5094699},"labels":[],"label_agreement":null},{"id":"W2889519581","doi":"10.3389/fnmol.2018.00255","title":"cAMP Response Element-Binding Protein (CREB): A Possible Signaling Molecule Link in the Pathophysiology of Schizophrenia","year":2018,"lang":"en","type":"review","venue":"Frontiers in Molecular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":449,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Science and Technology Planning Project of Guangdong Province; Fundo para o Desenvolvimento das Ciências e da Tecnologia; Hebrew University of Jerusalem; Universidade de Macau; National Natural Science Foundation of China","keywords":"CREB; Dopaminergic; Neuroscience; Neurotrophic factors; Dopamine; Brain-derived neurotrophic factor; Transcription factor; Neurotrophin; Cyclic AMP Response Element-Binding Protein; Neuronal memory allocation; Biology; CREB-binding protein; Synaptic plasticity; Receptor; Genetics; Gene; Metaplasticity","score_opus":0.01646935113813691,"score_gpt":0.276009600350634,"score_spread":0.2595402492124971,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2889519581","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09133795,0.8851717,0.020038377,0.000032680142,0.00093321176,0.0023449773,0.00007910154,0.000015010691,0.000046995432],"genre_scores_gemma":[0.010808678,0.9602353,0.026683608,0.00053494226,0.00033570308,0.00072643516,0.00023677948,0.00022661511,0.00021195778],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99490535,0.0018567024,0.0009267422,0.001158075,0.00045379304,0.00069932],"domain_scores_gemma":[0.998373,0.00003752951,0.00055687845,0.00089015753,0.00005746149,0.00008502155],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020493097,0.00051889196,0.0009814048,0.00049467647,0.000121906014,0.0000719781,0.0015730027,0.0004471904,0.0000073845085],"category_scores_gemma":[0.00054136786,0.00041226484,0.0003411456,0.0010619379,0.00034058286,0.000011663153,0.00033640122,0.0005423744,0.000003616834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019706681,0.000068701804,0.0000060482676,0.0006130668,0.000013612243,0.000095367825,0.00005002978,0.000059046324,0.98179704,0.000051983112,0.00012808006,0.016919982],"study_design_scores_gemma":[0.0019207958,0.0034754504,0.000008487077,0.008162641,0.00023796357,0.0001098176,0.00031719965,0.0006201952,0.65397424,0.0011646023,0.3277348,0.00227383],"about_ca_topic_score_codex":0.000009896884,"about_ca_topic_score_gemma":0.0000022135152,"teacher_disagreement_score":0.32782277,"about_ca_system_score_codex":0.000056732453,"about_ca_system_score_gemma":0.00051103137,"threshold_uncertainty_score":0.9998329},"labels":[],"label_agreement":null},{"id":"W2890098788","doi":"10.1096/fasebj.30.1_supplement.926.5","title":"Differential role of G protein signaling regulator RGS7 on rewarding effects of opioids and psychostimulants","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Regulator; Chemistry; Pharmacology; Differential effects; Neuroscience; Differential (mechanical device); Regulator of G protein signaling; Signal transduction; Cell biology; G protein; Biology; Medicine; GTPase-activating protein; Internal medicine; Biochemistry; Physics","score_opus":0.004828194321486553,"score_gpt":0.21374618069574366,"score_spread":0.20891798637425713,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890098788","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944497,0.0004600244,0.0047507384,0.000035051064,0.00012941871,0.00013252474,0.000004798804,0.0000022620734,0.00003549996],"genre_scores_gemma":[0.99926174,0.000087305605,0.00028560296,0.000012924631,0.00024774508,0.0000029876198,9.846764e-7,0.000013320644,0.000087381966],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992699,0.00009456116,0.0002077138,0.00012375272,0.0001593118,0.00014472925],"domain_scores_gemma":[0.99951327,0.00003654574,0.00018413625,0.00015330604,0.000051888113,0.000060842947],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021344546,0.00010176862,0.00015257299,0.00003533685,0.00007999472,0.000012244776,0.00013885055,0.000071474555,0.000041507807],"category_scores_gemma":[0.00006834407,0.000053537053,0.000087045926,0.000026962314,0.00005509322,0.0000035302564,0.000042563166,0.00007562402,6.8858895e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021194748,0.00002505648,0.00029361446,0.000021116077,0.000058823756,0.0000011112813,0.000054807562,0.000016147502,0.99141926,0.00013426536,0.00001218283,0.007751693],"study_design_scores_gemma":[0.0007739998,0.0005675837,0.0002856029,0.00037065247,0.000021451971,0.000018371395,0.000039255254,0.000028095335,0.99697965,0.0007972376,0.000042625514,0.000075456046],"about_ca_topic_score_codex":0.0000021261872,"about_ca_topic_score_gemma":1.9419528e-7,"teacher_disagreement_score":0.007676237,"about_ca_system_score_codex":0.000005710417,"about_ca_system_score_gemma":0.000021588447,"threshold_uncertainty_score":0.21831776},"labels":[],"label_agreement":null},{"id":"W2891821480","doi":"10.1038/d41586-018-06202-w","title":"Designer proteins activate fluorescent molecules","year":2018,"lang":"en","type":"letter","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Molecule; Fluorescence; Small molecule; Chemistry; Biophysics; Structural motif; Fluorescent protein; Computational biology; Protein design; Barrel (horology); Nanotechnology; Green fluorescent protein; Protein structure; Biochemistry; Biology; Materials science; Physics; Gene","score_opus":0.007513790478268303,"score_gpt":0.23548755800063897,"score_spread":0.22797376752237067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891821480","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0771637,0.024650201,0.030529242,0.83416426,0.012743644,0.006637315,0.00091011956,0.00044473461,0.012756793],"genre_scores_gemma":[0.014524676,0.00026184684,0.010880334,0.92880124,0.029356185,0.00014819858,0.0030998248,0.0002894718,0.012638241],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982731,0.00009797121,0.00018444209,0.0006702567,0.00034319705,0.00043105407],"domain_scores_gemma":[0.9990603,0.000006783593,0.00014154625,0.00055924646,0.00017312617,0.000059043166],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00012108528,0.000388746,0.00025033654,0.000064871936,0.00010212851,0.00006460522,0.00045341952,0.008376332,0.00031674266],"category_scores_gemma":[0.00006427382,0.000321956,0.0002192663,0.0000711175,0.00005861158,0.0000023361933,0.00013919988,0.0040642703,0.000054325217],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019149544,0.000007950927,0.0000012789336,0.000031434905,0.00005501348,0.000029695724,0.000005244489,7.950819e-7,0.4468488,0.000007857737,0.5526718,0.0003209751],"study_design_scores_gemma":[0.000102113445,0.000112056456,0.0000016953973,0.0000386909,0.000016194464,0.000008888471,0.0000018521819,0.0000028609695,0.47701198,0.00008348827,0.5223937,0.00022644305],"about_ca_topic_score_codex":0.000004662067,"about_ca_topic_score_gemma":0.0000018618681,"teacher_disagreement_score":0.09463697,"about_ca_system_score_codex":0.00002683404,"about_ca_system_score_gemma":0.000107288324,"threshold_uncertainty_score":0.9999232},"labels":[],"label_agreement":null},{"id":"W2892678288","doi":"10.1016/j.neuropharm.2018.09.020","title":"Muscarinic receptor antagonists activate ERK-CREB signaling to augment neurite outgrowth of adult sensory neurons","year":2018,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health; Tohoku University; University of Manitoba","keywords":"CREB; MAPK/ERK pathway; Muscarinic acetylcholine receptor; Neurite; Muscarinic acetylcholine receptor M1; Pirenzepine; Muscarinic acetylcholine receptor M3; Cell biology; Chemistry; Signal transduction; Muscarinic acetylcholine receptor M4; Biology; Receptor; Biochemistry; Transcription factor; In vitro","score_opus":0.013583482874141597,"score_gpt":0.2829000009286165,"score_spread":0.26931651805447493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2892678288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957707,0.000045414672,0.0007073606,0.00045268235,0.0020871023,0.00039690928,0.000049462018,0.000039658786,0.0004507426],"genre_scores_gemma":[0.99327475,0.00013692513,0.0011706314,0.0036108284,0.0011017411,0.00003149021,0.000025537473,0.00007462476,0.00057348335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977366,0.00030388302,0.000467853,0.0007438252,0.00020704042,0.0005407999],"domain_scores_gemma":[0.9987965,0.000056469493,0.00020146825,0.00038034713,0.00030608437,0.0002591259],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016031892,0.0003074934,0.0003367898,0.00013063007,0.00015832744,0.00002122767,0.0003898569,0.00017561892,0.0005741134],"category_scores_gemma":[0.0001374606,0.00031524067,0.00016620207,0.00019385788,0.00015663977,0.000007431118,0.00029903106,0.00022801508,0.00010328303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005664269,0.00011302651,0.00024304625,0.000025156261,0.000064768064,0.000017132565,0.00010692916,0.00011835601,0.9944566,0.00006460634,0.0024026104,0.0018213448],"study_design_scores_gemma":[0.0008563495,0.001974484,0.00027979736,0.000011816553,0.00004543657,0.000021806172,0.000032937034,0.00011161921,0.96815383,0.0000122802985,0.028229738,0.00026991908],"about_ca_topic_score_codex":0.000020020832,"about_ca_topic_score_gemma":0.0000048031566,"teacher_disagreement_score":0.026302781,"about_ca_system_score_codex":0.000019588682,"about_ca_system_score_gemma":0.00008757646,"threshold_uncertainty_score":0.99992996},"labels":[],"label_agreement":null},{"id":"W2894408196","doi":"10.1126/scisignal.aat7650","title":"Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9","year":2018,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":213,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Howard Hughes Medical Institute; Agence Nationale de la Recherche; Canadian Institutes of Health Research; U.S. Department of Veterans Affairs","keywords":"G protein-coupled receptor; CRISPR; Cell biology; Signal transduction; Biology; Chemistry; Genetics; Gene","score_opus":0.008870457717036463,"score_gpt":0.24791430956076754,"score_spread":0.2390438518437311,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2894408196","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99068207,0.00029204338,0.00833647,0.000031234882,0.00008806801,0.00014033286,0.0000039411175,0.000012325043,0.00041350667],"genre_scores_gemma":[0.9934758,0.000019471392,0.0062205363,0.00007751395,0.00014530045,0.0000055202963,0.000005110897,0.000018098832,0.00003263526],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998372,0.00004160568,0.00028906684,0.00055040134,0.00033222185,0.0004147069],"domain_scores_gemma":[0.9992424,0.00002023864,0.00014160914,0.00024420692,0.00023233825,0.00011915334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009936615,0.00017286265,0.0001899043,0.00018083326,0.00020433048,0.000068863636,0.000320472,0.00008575024,0.00006035262],"category_scores_gemma":[0.00011129146,0.00014477088,0.00003228284,0.00051717804,0.00047837434,0.000024900504,0.0001302304,0.000099295765,0.0000025749966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006424678,0.000022507456,0.0027761653,0.0000132996,0.000007881825,0.000004733541,0.00031364313,0.00039696848,0.99514896,0.00029727857,0.0000053482954,0.0009489762],"study_design_scores_gemma":[0.00037556284,0.00050339336,0.00038681584,0.0001251949,0.0000100765865,0.000016186985,0.0006920874,0.0012435556,0.9960574,0.00023823998,0.00014422095,0.00020727143],"about_ca_topic_score_codex":0.00005896664,"about_ca_topic_score_gemma":0.00008028947,"teacher_disagreement_score":0.0027937347,"about_ca_system_score_codex":0.000015260672,"about_ca_system_score_gemma":0.00017620709,"threshold_uncertainty_score":0.5903585},"labels":[],"label_agreement":null},{"id":"W2895823029","doi":"10.1101/447714","title":"MEK/mTOR-dependent D1 dopamine receptor activation induces local protein synthesis via eEF2 dephosphorylation in neurons","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Azrieli Foundation; Israel Science Foundation; International Development Research Centre; Canadian Institutes of Health Research; EU Joint Programme – Neurodegenerative Disease Research","keywords":"Dephosphorylation; Dopamine; Cell biology; Phosphorylation; Dopamine receptor; Translation (biology); Biology; Dopamine receptor D2; Dopamine receptor D1; PI3K/AKT/mTOR pathway; Messenger RNA; Signal transduction; Neuroscience; Phosphatase; Biochemistry; Gene","score_opus":0.010921961735619686,"score_gpt":0.21185189258286874,"score_spread":0.20092993084724906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2895823029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9710317,0.00031145703,0.026541281,0.0000902685,0.00078301295,0.0010615864,0.00007528183,0.00009515033,0.000010227229],"genre_scores_gemma":[0.9945362,0.00013325056,0.0037156087,0.00007283163,0.0008558,0.0005037016,0.00000522662,0.00016387661,0.0000134650145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966266,0.00028987834,0.0006881034,0.001363459,0.0004547447,0.00057719136],"domain_scores_gemma":[0.99780583,0.000031784944,0.0005333751,0.0010168828,0.0004019025,0.00021020962],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007148925,0.0006384608,0.0005128775,0.0002609619,0.00015731671,0.00014875484,0.000549916,0.0010766584,0.00017227976],"category_scores_gemma":[0.00036022917,0.0006993248,0.00016550803,0.0003032804,0.00012140511,0.00002718875,0.0004806434,0.0006065627,0.00004857313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001289153,0.00014439881,0.00049354235,0.00012407063,0.00008401968,0.0000051255674,0.000006323366,0.00016927141,0.9986769,0.00004947541,0.00006710153,0.00005084988],"study_design_scores_gemma":[0.00034633963,0.00015566015,0.0038062197,0.0003625567,0.00003944099,2.0544212e-8,0.000007648218,0.00025512726,0.99283516,0.0000035974979,0.001446139,0.00074210373],"about_ca_topic_score_codex":0.00016167153,"about_ca_topic_score_gemma":0.00001811433,"teacher_disagreement_score":0.023504505,"about_ca_system_score_codex":0.00021630357,"about_ca_system_score_gemma":0.0005277771,"threshold_uncertainty_score":0.9995458},"labels":[],"label_agreement":null},{"id":"W2896039488","doi":"10.1007/s00213-018-5065-7","title":"Impaired object-location learning and recognition memory but enhanced sustained attention in M2 muscarinic receptor-deficient mice","year":2018,"lang":"en","type":"article","venue":"Psychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Medical Research Council; Alzheimer's Research Trust; Wellcome Trust; Wellcome","keywords":"Muscarinic acetylcholine receptor; Neuroscience; Psychology; Cognitive flexibility; Acetylcholine; Cholinergic; Cognition; Muscarinic acetylcholine receptor M1; Muscarinic acetylcholine receptor M4; Receptor; Biology; Medicine; Endocrinology; Internal medicine","score_opus":0.010231467676572814,"score_gpt":0.2852126295589568,"score_spread":0.27498116188238403,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896039488","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945347,0.00040503964,0.0029467423,0.00010225822,0.0010011687,0.00034117053,0.0000030066024,0.000027853452,0.0006381161],"genre_scores_gemma":[0.9974551,0.00042420404,0.00050374155,0.00023815218,0.00048741914,0.0000801014,0.00013206498,0.000024553903,0.0006546294],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985934,0.00022956502,0.00028750044,0.0004903365,0.000088254215,0.00031095336],"domain_scores_gemma":[0.9994647,0.000022183824,0.00013720394,0.0000983332,0.00020378538,0.000073781746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044365687,0.00016035716,0.00015648034,0.00012766874,0.00012640552,0.000020042822,0.00008722447,0.00020551877,0.0003463961],"category_scores_gemma":[0.00007559641,0.00017602884,0.000048463335,0.00019226992,0.00008600164,0.000009582362,0.00005470608,0.00016322274,0.00004911582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005193036,0.00007123298,0.00022828115,0.000023744416,0.000025219733,9.3851725e-7,0.00022159677,0.000018957155,0.98066753,0.0000038382927,0.00025256482,0.017966801],"study_design_scores_gemma":[0.0030492018,0.0010124389,0.0013151088,0.000029582414,0.00003211162,0.000011420075,0.001375801,0.000531957,0.99058646,0.00013067186,0.0016275644,0.00029769918],"about_ca_topic_score_codex":0.000037475806,"about_ca_topic_score_gemma":0.00003093824,"teacher_disagreement_score":0.017669102,"about_ca_system_score_codex":0.000043369273,"about_ca_system_score_gemma":0.0000491465,"threshold_uncertainty_score":0.7178248},"labels":[],"label_agreement":null},{"id":"W2896400545","doi":"10.1038/s41386-018-0238-y","title":"Homeostatic cAMP regulation by the RGS7 complex controls depression-related behaviors","year":2018,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Mental Health; U.S. Department of Health and Human Services","keywords":"Mediator; Prefrontal cortex; Neuroscience; G protein-coupled receptor; Regulator; Chronic stress; Mechanism (biology); Antidepressant; Psychology; Signal transduction; Biology; Cell biology; Cognition; Genetics; Hippocampus; Gene","score_opus":0.011064343155211605,"score_gpt":0.29066543724962,"score_spread":0.2796010940944084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896400545","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950679,0.00034779703,0.0012875742,0.0005215658,0.0013714283,0.0004115702,0.00002390573,0.00003231008,0.000935942],"genre_scores_gemma":[0.99559176,0.0000696162,0.00011539971,0.0025886213,0.00035543597,0.000052759653,0.00011465093,0.000038043396,0.0010737086],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985499,0.00028565674,0.00029328192,0.00041929417,0.0001385702,0.00031329488],"domain_scores_gemma":[0.9993012,0.000040490653,0.00015176855,0.0002958351,0.00011539659,0.00009530996],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018630199,0.00018245578,0.00015965385,0.0000351497,0.00026878342,0.00002666554,0.00029263535,0.00015390934,0.0020781392],"category_scores_gemma":[0.00003245221,0.00013708504,0.00008195323,0.000121589495,0.00021543073,0.000004718574,0.000069856105,0.00016158169,0.00010414215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018730093,0.000055941095,0.0002774421,0.0000019948623,0.0000344974,0.0000025337206,0.000048287657,0.00002233987,0.9466057,0.000028003835,0.048612043,0.00412394],"study_design_scores_gemma":[0.0041439706,0.001114995,0.009362964,0.000007854899,0.000124792,0.000098275515,0.000053627627,0.0013662281,0.77195764,0.00027051682,0.21110106,0.00039808103],"about_ca_topic_score_codex":0.000008747353,"about_ca_topic_score_gemma":0.0000031285224,"teacher_disagreement_score":0.17464803,"about_ca_system_score_codex":0.000009361517,"about_ca_system_score_gemma":0.000026073058,"threshold_uncertainty_score":0.9988341},"labels":[],"label_agreement":null},{"id":"W2897059447","doi":"10.1038/s41589-018-0145-x","title":"Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist","year":2018,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":203,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; National Institutes of Health; National Institute of Neurological Disorders and Stroke; American Heart Association","keywords":"Partial agonist; Salmeterol; Agonist; G protein-coupled receptor; Chemistry; Receptor; Mutagenesis; Pharmacology; Biology; Biophysics; Biochemistry; Immunology; Asthma; Gene; Mutation","score_opus":0.014576297624579281,"score_gpt":0.2773813865597439,"score_spread":0.26280508893516463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897059447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99779093,0.0012690584,0.00014421748,0.000068944915,0.00037208953,0.000095533236,0.000009148785,0.0000110958135,0.00023896995],"genre_scores_gemma":[0.9973457,0.00007367287,0.0013070133,0.00012843132,0.0009547094,0.0000027566125,0.00015107333,0.000013990001,0.000022640597],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998996,0.00004944375,0.0002391684,0.00041812312,0.00007172725,0.00022549622],"domain_scores_gemma":[0.99947363,0.000034399043,0.000106557294,0.0001992688,0.000096207346,0.000089956215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009401771,0.00017048775,0.00023207396,0.000043086737,0.000077976634,0.000013836218,0.00019195056,0.00074820785,0.00007039221],"category_scores_gemma":[0.00020125178,0.00013165454,0.0000673484,0.00009274257,0.000401177,0.000002744612,0.00019328941,0.0002605244,0.000004580032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001514906,0.000015736863,0.00056164566,0.000010715963,0.000035259414,8.223393e-7,0.00007607931,1.7126607e-7,0.9954834,0.0014805043,0.00015305517,0.002031127],"study_design_scores_gemma":[0.0004832195,0.0003452132,0.00010357994,0.000010930547,0.0000122604615,0.000010170403,0.000020525646,0.000031929514,0.98488265,0.0009132005,0.013026328,0.00016001954],"about_ca_topic_score_codex":0.000009707691,"about_ca_topic_score_gemma":0.00000535807,"teacher_disagreement_score":0.012873272,"about_ca_system_score_codex":0.00000978756,"about_ca_system_score_gemma":0.000027695985,"threshold_uncertainty_score":0.5770864},"labels":[],"label_agreement":null},{"id":"W2897502407","doi":"10.1152/ajplung.00196.2018","title":"Protease-activated receptor-2 signaling through β-arrestin-2 mediates <i>Alternaria</i> alkaline serine protease-induced airway inflammation","year":2018,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; National Institute of Neurological Disorders and Stroke; Association for Applied Sport Psychology","keywords":"Alternaria; Protease; Serine protease; Immunology; Biology; Arrestin; Microbiology; Receptor; Biochemistry; G protein-coupled receptor; Enzyme; Botany","score_opus":0.007234455186906382,"score_gpt":0.23764953274973313,"score_spread":0.23041507756282675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897502407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99112266,0.0004458723,0.0071960604,0.00020465307,0.0004747822,0.00047339953,0.000012448628,0.000025613084,0.00004447955],"genre_scores_gemma":[0.9912484,0.0001630493,0.0059307087,0.00047075463,0.0018909563,0.00003710676,0.00015863545,0.00007863696,0.000021741358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970323,0.0006436436,0.0008046738,0.0006726494,0.0002557887,0.0005909309],"domain_scores_gemma":[0.9975627,0.000049230413,0.0011436876,0.00044857882,0.0005604988,0.0002352804],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045781033,0.0004869035,0.0008008688,0.00012719045,0.00021758248,0.000030853436,0.00041531975,0.00024180906,0.00013410122],"category_scores_gemma":[0.00018823412,0.0004199933,0.0002802555,0.00027825663,0.00059369585,0.000040228144,0.0002048311,0.00041553882,0.000012901431],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009823164,0.000095844356,0.000027489144,0.000052080333,0.00036036765,0.000012392155,0.00022370934,0.00021462362,0.9962747,0.00008136826,0.00014772263,0.0015273617],"study_design_scores_gemma":[0.0011030169,0.0043947957,0.000094532814,0.00008915003,0.00009131217,0.00006660576,0.0002357036,0.00022944041,0.9899963,0.00050347147,0.0027399445,0.00045569098],"about_ca_topic_score_codex":0.00007438949,"about_ca_topic_score_gemma":0.000001915516,"teacher_disagreement_score":0.0062783887,"about_ca_system_score_codex":0.000033054348,"about_ca_system_score_gemma":0.00018118537,"threshold_uncertainty_score":0.9998252},"labels":[],"label_agreement":null},{"id":"W2897505090","doi":"10.1152/ajpheart.00560.2018","title":"VNUT and VMAT2 segregate within sympathetic varicosities and localize near preferred Cav2 isoforms in the rat tail artery","year":2018,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Government of Canada","keywords":"Synaptic vesicle; Free nerve ending; Vesicle; Gene isoform; Biology; Suramin; Chemistry; Cell biology; Endocrinology; Internal medicine; Biochemistry; Medicine","score_opus":0.008471568495799877,"score_gpt":0.22265179897967155,"score_spread":0.21418023048387166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897505090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984428,0.0010737389,0.000024399393,0.00011958513,0.00020194733,0.000113683695,0.0000033568556,0.0000045374477,0.000015904146],"genre_scores_gemma":[0.99790376,0.0002626263,0.00024376414,0.0012201801,0.00032566226,0.00000714479,0.000006580774,0.000019166378,0.000011115319],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9984981,0.00033647742,0.00038315353,0.0003645886,0.00010028319,0.00031740495],"domain_scores_gemma":[0.9992087,0.00005253845,0.00029596355,0.00024395407,0.00009431574,0.00010452419],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004329146,0.00023360451,0.0004942976,0.00006662245,0.00019900182,0.000032745134,0.00016336159,0.00012881857,0.000015284702],"category_scores_gemma":[0.000023866121,0.0001561113,0.00008475494,0.00010289522,0.001579337,0.00002145788,0.000089362125,0.00025378691,0.00000201448],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015884395,0.00004530077,0.00076805305,0.000018928342,0.000069914815,7.376854e-7,0.0012539533,0.000035808527,0.9969628,0.0001039851,0.000090882626,0.0004908132],"study_design_scores_gemma":[0.0036488425,0.015647639,0.8254346,0.00021269034,0.00023764874,0.0024109005,0.011792822,0.0021559442,0.11794594,0.013019412,0.0062313997,0.0012621165],"about_ca_topic_score_codex":0.000029043009,"about_ca_topic_score_gemma":0.000008807059,"teacher_disagreement_score":0.8790168,"about_ca_system_score_codex":0.0000094538245,"about_ca_system_score_gemma":0.000078188896,"threshold_uncertainty_score":0.6366034},"labels":[],"label_agreement":null},{"id":"W2897711708","doi":"10.1161/circ.132.suppl_3.12265","title":"Abstract 12265: Normalization of Renal AT1 Receptor Expression is Observed With Enalapril But Not Diltiazem in a Rat Model of Chronic Kidney Disease","year":2015,"lang":"en","type":"article","venue":"Circulation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Enalapril; Angiotensin II receptor type 1; Kidney disease; Diltiazem; Internal medicine; Kidney; Cardiology; Receptor; Pharmacology; Angiotensin II; Endocrinology; Angiotensin-converting enzyme; Calcium; Blood pressure","score_opus":0.03425452359851026,"score_gpt":0.23910562231953594,"score_spread":0.2048510987210257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897711708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9523883,0.00017183299,0.04707447,0.000028027209,0.000061764185,0.00018658981,0.0000376863,0.0000057245697,0.000045605797],"genre_scores_gemma":[0.9984309,0.000032318698,0.0008566132,0.000040971627,0.00007679014,0.000013648028,0.00049561396,0.00001834968,0.000034807465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904805,0.000037223224,0.00030563556,0.0002392396,0.00023033694,0.00013948392],"domain_scores_gemma":[0.9992137,0.0000046587347,0.00022685235,0.00023067473,0.0001854652,0.00013862412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020329261,0.00011817722,0.00014753555,0.00005395042,0.0000244147,0.0000085583915,0.0000879708,0.0001132038,0.000045893998],"category_scores_gemma":[0.00007161433,0.00010613017,0.00004981496,0.00008959488,0.000028038789,0.000020512734,0.000033408913,0.000048657752,0.0000013176076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035783692,0.00006079951,0.0047080102,0.00007190861,0.000008557826,3.4852906e-7,0.00012324906,0.1153001,0.8790064,0.000032921438,0.000088786015,0.0002410872],"study_design_scores_gemma":[0.0010494972,0.000084269115,0.0021830387,0.00016327233,0.000014383537,3.5010365e-7,0.000027682574,0.07993273,0.91625136,0.00007557328,0.00009213108,0.00012571922],"about_ca_topic_score_codex":0.00003009348,"about_ca_topic_score_gemma":0.000009603755,"teacher_disagreement_score":0.046217855,"about_ca_system_score_codex":0.00004439781,"about_ca_system_score_gemma":0.00030771815,"threshold_uncertainty_score":0.43278626},"labels":[],"label_agreement":null},{"id":"W2897757945","doi":"10.1016/j.bcp.2018.10.017","title":"BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes","year":2018,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; Japan Science and Technology Agency; Japan Society for the Promotion of Science; National Health and Medical Research Council; Japan Agency for Medical Research and Development","keywords":"Transactivation; Epidermal growth factor receptor; Angiotensin II; GRB2; Cell biology; Epidermal growth factor; Cancer research; Growth factor receptor; Receptor; Chemistry; Biology; Tyrosine kinase; Signal transduction; Biochemistry; Transcription factor","score_opus":0.012082537537114814,"score_gpt":0.2790622827763281,"score_spread":0.2669797452392133,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897757945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9211453,0.0001815236,0.07522389,0.0023116446,0.000247058,0.0007663803,0.000035609217,0.000025637995,0.00006292256],"genre_scores_gemma":[0.99529564,0.000009270545,0.0010179607,0.0022602607,0.0007987394,0.00016847906,0.00012484436,0.000031354593,0.00029344638],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984605,0.00019749925,0.0002800679,0.0005171263,0.00019709708,0.00034771767],"domain_scores_gemma":[0.9992977,0.00006594648,0.00012028117,0.00019619311,0.000155953,0.00016392455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037643386,0.0002313092,0.0001948625,0.00004137669,0.00020255866,0.000035597037,0.0002495478,0.00028342564,0.00028437618],"category_scores_gemma":[0.000077881676,0.00018721746,0.00007254501,0.000119786964,0.00016841872,0.000008426365,0.00006694614,0.00015659063,0.000011714608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031890834,0.000082504135,0.00002677067,0.000017771705,0.000043588654,4.2849214e-7,0.000037320828,0.000012318802,0.94579136,0.000031834166,0.052912142,0.00072505546],"study_design_scores_gemma":[0.0008562568,0.00039177423,0.000071543145,0.00001696658,0.000031063744,0.0000032221603,0.000034305845,0.00027970676,0.9755007,0.00009780691,0.022483414,0.00023320693],"about_ca_topic_score_codex":0.000040506904,"about_ca_topic_score_gemma":0.0000018924899,"teacher_disagreement_score":0.07420593,"about_ca_system_score_codex":0.000057073084,"about_ca_system_score_gemma":0.000043654694,"threshold_uncertainty_score":0.7634506},"labels":[],"label_agreement":null},{"id":"W2900014623","doi":"10.1073/pnas.1813988115","title":"Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists","year":2018,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Institute of General Medical Sciences","keywords":"Muscarinic acetylcholine receptor; Selectivity; Antagonist; Chemistry; Docking (animal); Muscarinic antagonist; In vivo; Acetylcholine; Receptor; Binding site; Pharmacology; Stereochemistry; Biochemistry; Biophysics; Biology; Medicine; Biotechnology","score_opus":0.033645227064244936,"score_gpt":0.3148636668340939,"score_spread":0.28121843976984895,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900014623","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9985632,0.000058751233,0.000015032708,0.00016208479,0.000036922072,0.00010709337,0.000013275431,0.0000025198967,0.001041135],"genre_scores_gemma":[0.9833297,0.000014431399,0.01632223,0.00008496799,0.00015045404,0.0000029457217,8.330231e-7,0.000004083396,0.00009035572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99881,0.0000054023417,0.00031825504,0.0002237029,0.00052130216,0.00012135812],"domain_scores_gemma":[0.9990335,0.000011465851,0.0003880177,0.000008947764,0.00053288933,0.000025179732],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065805187,0.00008422692,0.00012299979,0.00006352175,0.00015112066,0.000008248398,0.00049729366,0.00010131268,0.000037638354],"category_scores_gemma":[0.00024560167,0.000057884226,0.000053886502,0.00031409063,0.000475501,0.00001430173,0.00014532743,0.000068838686,4.8822096e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020215335,0.000015996888,0.0006927357,0.000018789096,0.000022335073,2.43318e-10,0.00017973346,0.000008018556,0.996501,0.0014439967,0.0005076305,0.0005895303],"study_design_scores_gemma":[0.00014059257,0.00008929423,0.004584299,0.00003114698,0.0000048551287,0.0000023164023,0.00008427868,0.000048905553,0.99173254,0.0023769834,0.00083748094,0.00006729844],"about_ca_topic_score_codex":0.0000023341427,"about_ca_topic_score_gemma":2.2752191e-7,"teacher_disagreement_score":0.016307198,"about_ca_system_score_codex":0.000015520922,"about_ca_system_score_gemma":0.00009251056,"threshold_uncertainty_score":0.23604502},"labels":[],"label_agreement":null},{"id":"W290006620","doi":"10.1139/y08-056","title":"Urinary protein profiling with surface-enhanced laser desorption/ionization time-of-flight mass spectrometry in ET<sub>B</sub>receptor-deficient ratsThis article is one of a selection of papers published in the special issue (part 2 of 2) on Forefronts in Endothelin.","year":2008,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Deutsche Forschungsgemeinschaft; Howard Hughes Medical Institute","keywords":"Albuminuria; Chemistry; Urinary system; Excretion; Endocrinology; Kidney; Internal medicine; Urine; Renal function; Receptor; Mass spectrometry; Medicine; Biochemistry; Chromatography","score_opus":0.007919975901008545,"score_gpt":0.21731886908286474,"score_spread":0.2093988931818562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W290006620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99928254,0.00010765502,0.00006478566,0.00012606264,0.00009209373,0.00024619262,0.000014742691,4.6655393e-7,0.00006544972],"genre_scores_gemma":[0.99921215,0.00014863224,0.00037133106,0.00008942557,0.00014234977,0.0000059215117,0.0000108906515,0.000007534608,0.000011754614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989088,0.0002817726,0.0004125964,0.00014379037,0.000080845515,0.00017218034],"domain_scores_gemma":[0.99939716,0.000029951134,0.00033190261,0.00005952234,0.00012956581,0.000051883708],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004018867,0.000094411625,0.00027881953,0.00021513551,0.000028498558,0.0000018553492,0.000097472934,0.00012183957,0.0010470208],"category_scores_gemma":[0.000030102357,0.00007650227,0.000040632884,0.0002840705,0.00013369475,0.000015977634,0.0000075891103,0.00018608375,4.2623913e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008424292,0.0001699449,0.0027008175,0.000042399413,0.00003957787,0.000004424276,0.0006327168,0.0029679565,0.9924323,0.00001914548,0.000086390486,0.00006190379],"study_design_scores_gemma":[0.0012298245,0.001563364,0.002708487,0.000049789513,0.000012291139,0.000011619308,0.00015071721,0.00010567638,0.99397796,0.00008076137,0.000043970995,0.00006553978],"about_ca_topic_score_codex":0.00009304497,"about_ca_topic_score_gemma":0.000366787,"teacher_disagreement_score":0.00286228,"about_ca_system_score_codex":0.000033947545,"about_ca_system_score_gemma":0.0003246269,"threshold_uncertainty_score":0.9998661},"labels":[],"label_agreement":null},{"id":"W2900782570","doi":"10.1016/j.neuropharm.2018.11.029","title":"The high efficacy of muscarinic M4 receptor in D1 medium spiny neurons reverses striatal hyperdopaminergia","year":2018,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Servier; Vetenskapsrådet; Agence Nationale de la Recherche; Horizon 2020 Framework Programme; Swedish e-Science Research Centre; National Alliance for Research on Schizophrenia and Depression","keywords":"Medium spiny neuron; Muscarinic acetylcholine receptor; Acetylcholine; Dopamine; Striatum; Oxotremorine; Muscarinic acetylcholine receptor M4; Neuroscience; Muscarinic acetylcholine receptor M1; Agonist; Dopamine receptor; Chemistry; Dopamine receptor D1; Pharmacology; Biology; Receptor; Biochemistry","score_opus":0.01103945140620933,"score_gpt":0.2694742814453448,"score_spread":0.2584348300391355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900782570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959871,0.00019393799,0.000027331824,0.0003877069,0.0028924716,0.00023602301,0.000021329453,0.00001312831,0.00024092557],"genre_scores_gemma":[0.9974476,0.00052645546,0.00013189552,0.0004574377,0.0009812132,0.000017230595,0.000019854046,0.0000330812,0.00038520718],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998413,0.00028974682,0.00037828315,0.0004134404,0.00013827732,0.00036720576],"domain_scores_gemma":[0.999194,0.00015251002,0.0001547185,0.0003199443,0.000095670955,0.00008314969],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025399966,0.00018094973,0.00021818126,0.000061206745,0.000117370066,0.000012360073,0.00042522696,0.00013882788,0.00046092662],"category_scores_gemma":[0.00031592732,0.00014418,0.00009684136,0.00017402084,0.0002795372,0.0000045653182,0.00022725167,0.00020355922,0.00003421491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034614807,0.00007616734,0.00026584388,0.000006701455,0.000027236436,0.0000069151106,0.000023010349,0.000034916287,0.9938406,0.00009329833,0.0035252245,0.0017539618],"study_design_scores_gemma":[0.0017299266,0.0012110727,0.007319198,0.000006517895,0.000028319517,0.000009462023,0.000030309817,0.000045245164,0.9195018,0.000014853931,0.06995387,0.00014947173],"about_ca_topic_score_codex":0.000040262566,"about_ca_topic_score_gemma":0.00003131473,"teacher_disagreement_score":0.07433882,"about_ca_system_score_codex":0.00001153797,"about_ca_system_score_gemma":0.000106234584,"threshold_uncertainty_score":0.587949},"labels":[],"label_agreement":null},{"id":"W2901524433","doi":"10.1097/fjc.0000000000000535","title":"Nucleoligands-repurposing G Protein–coupled Receptor Ligands to Modulate Nuclear-localized G Protein–coupled Receptors in the Cardiovascular System","year":2017,"lang":"en","type":"review","venue":"Journal of Cardiovascular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute; McGill University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Receptor; Pharmacophore; Rhodopsin-like receptors; Cell biology; Biology; Signal transduction; Intracellular; Cell signaling; Nuclear receptor; Computational biology; Bioinformatics; Biochemistry; Metabotropic receptor","score_opus":0.03341802226023279,"score_gpt":0.3060903496039545,"score_spread":0.2726723273437217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901524433","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013008651,0.976557,0.0019615302,0.00006569164,0.0031514002,0.0050754747,0.000019616393,0.00003461989,0.00012602634],"genre_scores_gemma":[0.011596124,0.98070043,0.001306417,0.00011685969,0.0050685937,0.00062543084,0.000058171012,0.00037811926,0.00014985508],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99134785,0.0022161969,0.0024887603,0.0012519947,0.0015798698,0.0011153003],"domain_scores_gemma":[0.99484843,0.00005581074,0.0018081105,0.0021371967,0.0006810211,0.00046944327],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.009244878,0.0012287605,0.0057568285,0.0006609829,0.00052439823,0.00030111082,0.0027638671,0.0013397149,0.00010237844],"category_scores_gemma":[0.00033683723,0.000896104,0.009871802,0.000547962,0.00017796982,0.00004637399,0.00049867074,0.0016210866,0.000059130536],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013045109,0.00052573864,0.0000014042902,0.019545088,0.07463579,0.0020579714,0.0006883781,0.008953408,0.121463455,0.00010207282,0.0033578053,0.7673644],"study_design_scores_gemma":[0.002747491,0.00068943034,2.6388457e-7,0.0057666795,0.0062956405,0.0012481954,0.00013402026,0.0001507983,0.007520979,0.000005763032,0.9744919,0.00094885123],"about_ca_topic_score_codex":0.00006242739,"about_ca_topic_score_gemma":0.0000018914831,"teacher_disagreement_score":0.97113407,"about_ca_system_score_codex":0.00041460784,"about_ca_system_score_gemma":0.0007803661,"threshold_uncertainty_score":0.9999567},"labels":[],"label_agreement":null},{"id":"W2902049135","doi":"10.1126/scisignal.aat1631","title":"Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors","year":2018,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":156,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Institute for Research in Immunology and Cancer; Centre Hospitalier Universitaire Sainte-Justine; Université de Sherbrooke; Université de Montréal; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Functional selectivity; Signal transduction; Receptor; Effector; Cell biology; Arrestin; Biology; Cell signaling; Chemistry; Biochemistry","score_opus":0.021720714983963094,"score_gpt":0.2484995417986705,"score_spread":0.2267788268147074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902049135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98529375,0.000110090215,0.012965576,0.00005864117,0.0012244383,0.00021007076,0.000008914485,0.000020263406,0.00010827044],"genre_scores_gemma":[0.9844993,0.000002839026,0.014448931,0.00013499236,0.000759452,0.0000019088423,0.00000771703,0.000026192083,0.00011870416],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978269,0.00011458138,0.00034309234,0.00062218454,0.0005876366,0.0005056037],"domain_scores_gemma":[0.9983281,0.000037921596,0.00025496294,0.0003834427,0.00088744704,0.00010812288],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015749397,0.0002107563,0.00019994847,0.000109374305,0.0011845034,0.00005888804,0.00041355603,0.00014076105,0.000143372],"category_scores_gemma":[0.0004987163,0.00016591238,0.00015165118,0.0010419213,0.0006905718,0.00002896474,0.00030836146,0.00017060047,0.000006097805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005405195,0.00002010371,0.0011130297,0.0000069897987,0.000018555704,3.1270346e-7,0.00016438216,0.0041816398,0.9939895,0.00019036801,0.000050907245,0.00021014847],"study_design_scores_gemma":[0.00015734196,0.00025307274,0.000111682195,0.00006799335,0.000016045129,0.000012701055,0.00022249833,0.0039268453,0.9944172,0.00025789757,0.0003347102,0.00022202791],"about_ca_topic_score_codex":0.000034480836,"about_ca_topic_score_gemma":0.0000046412033,"teacher_disagreement_score":0.0014833555,"about_ca_system_score_codex":0.000060615854,"about_ca_system_score_gemma":0.0007233703,"threshold_uncertainty_score":0.91103625},"labels":[],"label_agreement":null},{"id":"W2902416049","doi":"10.1016/j.phrs.2018.12.001","title":"A fresh look at cortical dopamine D2 receptor expressing neurons","year":2018,"lang":"en","type":"review","venue":"Pharmacological Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Neuroscience; Dopamine receptor D2; Nucleus accumbens; Basal ganglia; Context (archaeology); Dopamine; Schizophrenia (object-oriented programming); Psychology; Biology; Central nervous system; Psychiatry","score_opus":0.21089029137766727,"score_gpt":0.47045915090811535,"score_spread":0.25956885953044806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902416049","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.003777656,0.9922365,0.00015918663,0.000046403813,0.0006340392,0.0011615166,0.0000930046,0.000043475313,0.0018482424],"genre_scores_gemma":[0.0005968939,0.99015236,0.00050522026,0.000116019415,0.002689272,0.0004552058,0.00040458827,0.00010518987,0.00497524],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99360013,0.0021474704,0.0007093332,0.0013880234,0.0008530317,0.0013020043],"domain_scores_gemma":[0.9977967,0.00054475723,0.00017538328,0.0005406021,0.00033562168,0.00060692255],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0022260498,0.00053646666,0.0010464268,0.00017481175,0.00064538384,0.00013570696,0.0010794728,0.00086673576,0.009641901],"category_scores_gemma":[0.0012003937,0.00039053956,0.0005960052,0.00038246706,0.00065154926,0.000005650281,0.001985508,0.0015508274,0.0011865061],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002997587,0.00045015727,0.0000053910903,0.002154302,0.00037079494,0.00013341097,0.000015281117,0.0000010773183,0.55099744,0.00006576802,0.18145275,0.26405385],"study_design_scores_gemma":[0.0003124951,0.00078159646,6.119798e-7,0.0006680363,0.00014963052,0.000037784142,0.0000099966055,0.000018429246,0.036582645,0.000020934363,0.96100205,0.0004158059],"about_ca_topic_score_codex":0.0000044197945,"about_ca_topic_score_gemma":0.0000030983174,"teacher_disagreement_score":0.7795493,"about_ca_system_score_codex":0.00018159833,"about_ca_system_score_gemma":0.00038817586,"threshold_uncertainty_score":0.9998546},"labels":[],"label_agreement":null},{"id":"W2902593776","doi":"10.3389/fncel.2018.00450","title":"Endocytosis of Activated Muscarinic m2 Receptor (m2R) in Live Mouse Hippocampal Neurons Occurs via a Clathrin-Dependent Pathway","year":2018,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"Agence Nationale de la Recherche","keywords":"Endocytosis; Clathrin; Cell biology; Internalization; Endosome; Receptor-mediated endocytosis; Muscarinic acetylcholine receptor; Receptor; G protein-coupled receptor; Biology; Muscarinic acetylcholine receptor M1; Chemistry; Signal transduction; Biochemistry","score_opus":0.011927441202375648,"score_gpt":0.2248162427026649,"score_spread":0.21288880150028924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902593776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9802005,0.00019265749,0.017299661,0.000022656348,0.0018174947,0.00032081272,0.00002463197,0.000015557587,0.00010602062],"genre_scores_gemma":[0.9969183,0.00017495532,0.002296662,0.00015757496,0.000102042904,0.000022891414,0.000015885218,0.000033525346,0.00027815334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976398,0.00021339943,0.00045087028,0.0008285356,0.00032678797,0.00054060743],"domain_scores_gemma":[0.99908555,0.000015490932,0.00019820068,0.00049837615,0.00006852473,0.00013383532],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038882502,0.0002551264,0.00030904677,0.000224961,0.00008998036,0.000031282983,0.0006178416,0.00018734066,0.0000471241],"category_scores_gemma":[0.0001836204,0.0002638064,0.000114325856,0.00045208947,0.00033384378,0.00002155893,0.00024212478,0.00025771747,0.0000069889816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011800552,0.00014445216,0.005156163,0.000011688029,0.0000040295413,0.000014152598,0.00022354948,0.00013505503,0.99185616,0.000009837334,0.00014712884,0.0021798054],"study_design_scores_gemma":[0.0005749954,0.0006748554,0.00039534742,0.000022860157,0.000004812935,0.000005036068,0.00020549523,0.0015126838,0.99471056,0.00006657023,0.0015728109,0.00025399536],"about_ca_topic_score_codex":0.000076555385,"about_ca_topic_score_gemma":0.00003243339,"teacher_disagreement_score":0.0167178,"about_ca_system_score_codex":0.000050442504,"about_ca_system_score_gemma":0.00013404689,"threshold_uncertainty_score":0.9999814},"labels":[],"label_agreement":null},{"id":"W2902863424","doi":"10.1038/s41589-018-0182-5","title":"Publisher Correction: Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist","year":2018,"lang":"en","type":"erratum","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Computational biology; Partial agonist; Agonist; Computer science; Biology; Receptor; Genetics","score_opus":0.011885427062978583,"score_gpt":0.2672088003042121,"score_spread":0.25532337324123355,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902863424","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89392203,0.01360771,0.00014318907,0.00018744745,0.08531141,0.00043606796,0.000045971534,0.000049508766,0.006296645],"genre_scores_gemma":[0.9671606,0.00097478786,0.000837504,0.00027264943,0.012193504,0.0000188066,0.006284597,0.00009477653,0.012162775],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978537,0.000112486996,0.00050483254,0.0009585802,0.00017687648,0.00039350952],"domain_scores_gemma":[0.9987164,0.000054888933,0.00038233228,0.00042451714,0.0002615527,0.00016028988],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00016457697,0.00046766512,0.00064347964,0.00012553304,0.00012383636,0.00006964339,0.00044769194,0.0043722205,0.00017720913],"category_scores_gemma":[0.00057146064,0.00037670828,0.00019749359,0.00018135316,0.0005181039,0.000006976183,0.00042764744,0.0014938974,0.000005638739],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014505799,0.000022071898,0.00006795539,0.000045763227,0.00010941742,0.0000018874989,0.000043062457,1.373019e-7,0.6339042,0.000119798286,0.36436325,0.0011773874],"study_design_scores_gemma":[0.00042718707,0.0003460206,0.00001879512,0.000060942897,0.00004573013,0.000025043857,0.000020431078,0.000019590238,0.49600852,0.0005784881,0.50208604,0.00036321845],"about_ca_topic_score_codex":0.000026606576,"about_ca_topic_score_gemma":0.00001883276,"teacher_disagreement_score":0.13789569,"about_ca_system_score_codex":0.000039828697,"about_ca_system_score_gemma":0.00015323733,"threshold_uncertainty_score":0.9998685},"labels":[],"label_agreement":null},{"id":"W2902881290","doi":"10.1534/genetics.118.301733","title":"Coupling of Human Rhodopsin to a Yeast Signaling Pathway Enables Characterization of Mutations Associated with Retinal Disease","year":2018,"lang":"en","type":"article","venue":"Genetics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Rhodopsin; Biology; G protein-coupled receptor; Retinitis pigmentosa; Genetics; Arrestin; Phenotype; Retinal degeneration; Mutation; Mutant; Model organism; Signal transduction; Computational biology; Cell biology; Retinal; Gene; Biochemistry","score_opus":0.01403242930961581,"score_gpt":0.24190173961748576,"score_spread":0.22786931030786994,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902881290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97794867,0.000031715263,0.021699056,0.000010951441,0.00004009962,0.00014596542,0.000090921305,0.0000061360556,0.000026465363],"genre_scores_gemma":[0.9976234,0.000004695002,0.0017504432,0.000023909624,0.00012759621,0.000008045936,0.00036570887,0.000021772064,0.00007445225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992829,0.000020316445,0.00022714943,0.00018417921,0.00014500701,0.00014045533],"domain_scores_gemma":[0.99924135,0.0000056634453,0.00017086595,0.0001636713,0.00033623175,0.0000822084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014807271,0.00009684785,0.00012411104,0.000046002708,0.00007813015,0.000011522038,0.00009683293,0.000060173872,0.000043281943],"category_scores_gemma":[0.000057989062,0.00009311677,0.000037889855,0.00012500392,0.000065073014,0.0000021870517,0.000038718943,0.000028720537,0.0000011280906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050077037,0.000046726767,0.0020919987,0.000017497436,0.000029702824,6.5329834e-7,0.0001656853,0.0009030043,0.9965096,0.00005479487,0.0000045347424,0.0001257142],"study_design_scores_gemma":[0.00021398375,0.00060140755,0.003842589,0.0001049998,0.000031310312,4.9434016e-7,0.0000867702,0.0006135755,0.9942615,0.00003590216,0.000092125345,0.00011535608],"about_ca_topic_score_codex":0.0000032779997,"about_ca_topic_score_gemma":0.000013715125,"teacher_disagreement_score":0.019948611,"about_ca_system_score_codex":0.000007725181,"about_ca_system_score_gemma":0.00007652133,"threshold_uncertainty_score":0.37971917},"labels":[],"label_agreement":null},{"id":"W2903412904","doi":"10.1126/scisignal.aar5536","title":"FZD <sub>5</sub> is a Gα <sub>q</sub> -coupled receptor that exhibits the functional hallmarks of prototypical GPCRs","year":2018,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Institute for Research in Immunology and Cancer","funders":"Novo Nordisk Fonden; FP7 People: Marie-Curie Actions; Vetenskapsrådet; Canadian Institutes of Health Research; Stiftelsen Olle Engkvist Byggmästare; Novo Nordisk; Deutsche Forschungsgemeinschaft; Knut och Alice Wallenbergs Stiftelse; Svenska Sällskapet för Medicinsk Forskning; Cancerfonden","keywords":"Heterotrimeric G protein; G protein-coupled receptor; Receptor; Cell biology; G protein; Chemistry; Signal transduction; Ligand (biochemistry); Gq alpha subunit; Biology; Biochemistry","score_opus":0.01780578531593706,"score_gpt":0.2378669951124076,"score_spread":0.22006120979647054,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2903412904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98085654,0.00021853691,0.016998192,0.00024060957,0.00080473453,0.00062037614,0.000012896437,0.0000251535,0.0002229491],"genre_scores_gemma":[0.9974771,0.000051717372,0.0008783582,0.00050563057,0.0009156628,0.000085965294,0.00002046097,0.000032810396,0.000032303138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99703366,0.00009886836,0.0004433813,0.000860774,0.0008921172,0.0006711753],"domain_scores_gemma":[0.998392,0.000051041832,0.00027510742,0.00053234363,0.0005462943,0.00020325038],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018876522,0.0002947805,0.00026628567,0.00012955721,0.00072293886,0.00012737892,0.0006781628,0.0002229414,0.00022846296],"category_scores_gemma":[0.00025715065,0.00022069452,0.00021974828,0.00058473786,0.0011266723,0.000038548016,0.00027090262,0.00023308673,0.000055061137],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015726832,0.00004975393,0.00024245176,0.000016605363,0.000029214898,7.4093816e-7,0.00021579093,0.000096108284,0.99497145,0.00018754402,0.00045570184,0.0035773795],"study_design_scores_gemma":[0.00038852764,0.0004286811,0.00032064752,0.000079912104,0.000021229635,0.000012996375,0.00026041392,0.0015993089,0.99559504,0.00037521526,0.0006268392,0.00029121054],"about_ca_topic_score_codex":0.000009195986,"about_ca_topic_score_gemma":0.000008973292,"teacher_disagreement_score":0.01662054,"about_ca_system_score_codex":0.000044329827,"about_ca_system_score_gemma":0.00048737656,"threshold_uncertainty_score":0.8999661},"labels":[],"label_agreement":null},{"id":"W2904591566","doi":"10.1139/cjpp-2018-0531","title":"β-1 adrenoceptors and AT1 receptors may not be involved in catecholamine-induced lethal arrhythmias","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Receptor; Catecholamine; Adrenergic receptor; Internal medicine; Angiotensin II receptor type 1; Endocrinology; Pharmacology; Medicine; Chemistry; Biology; Angiotensin II","score_opus":0.021296327452779696,"score_gpt":0.273269004124321,"score_spread":0.2519726766715413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2904591566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99657905,0.0007423582,0.000016832424,0.0010234548,0.0014530008,0.00009341729,0.000008463798,0.0000020552307,0.000081376325],"genre_scores_gemma":[0.99702847,0.00015698856,0.0001697604,0.0014485961,0.0010861087,0.0000042077368,0.000010932919,0.0000172435,0.00007767769],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988081,0.00019684294,0.00031171177,0.0002643067,0.000047749072,0.0003713091],"domain_scores_gemma":[0.9992138,0.00003462872,0.00016620068,0.00008523663,0.00012907619,0.00037101778],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003763691,0.00017396129,0.00028880345,0.0002046169,0.00013530371,0.00001116324,0.00014931682,0.00030897566,0.00097429537],"category_scores_gemma":[0.000048036716,0.0001634606,0.000054024553,0.00009432369,0.00033506766,0.000012416021,0.000036047782,0.00031452574,0.000002373816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017246943,0.000009911335,0.0011546342,0.000014129658,0.00006254414,0.000039797033,0.00032095663,0.000008281347,0.99543417,0.000070706454,0.0018512211,0.0008612134],"study_design_scores_gemma":[0.0010258117,0.0010456383,0.002183983,0.000013584915,0.000027121507,0.00014382145,0.00017603072,0.000018455376,0.97126144,0.00019933404,0.0237236,0.0001811888],"about_ca_topic_score_codex":0.0004257971,"about_ca_topic_score_gemma":0.0016861352,"teacher_disagreement_score":0.024172705,"about_ca_system_score_codex":0.000028857095,"about_ca_system_score_gemma":0.00037735116,"threshold_uncertainty_score":0.99993896},"labels":[],"label_agreement":null},{"id":"W2905071518","doi":"10.3390/biom8040180","title":"Combining Optical Approaches with Human Inducible Pluripotent Stem Cells in G Protein-Coupled Receptor Drug Screening and Development","year":2018,"lang":"en","type":"review","venue":"Biomolecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Induced pluripotent stem cell; Drug discovery; Embryonic stem cell; G protein-coupled receptor; Computational biology; HEK 293 cells; Receptor; Biology; Drug development; Cell biology; Drug; Neuroscience; Signal transduction; Bioinformatics; Pharmacology; Biochemistry; Gene","score_opus":0.07006751419852889,"score_gpt":0.270292065881811,"score_spread":0.2002245516832821,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2905071518","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.044278324,0.94870985,0.0051664077,0.000010038476,0.0000923127,0.0015881705,0.000014451899,0.000031152875,0.00010927902],"genre_scores_gemma":[0.017767098,0.8539388,0.122851655,0.000048882506,0.0007069303,0.0013641431,0.0012610595,0.0005163476,0.0015450704],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.997457,0.00015246349,0.000631635,0.0010171741,0.00025958268,0.00048208897],"domain_scores_gemma":[0.9990802,0.000013849205,0.0003013363,0.0003839683,0.000054059994,0.00016658026],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005631755,0.0005802845,0.00089185237,0.00018005013,0.00018101576,0.00011984833,0.00031913837,0.00042726053,0.00001748843],"category_scores_gemma":[0.000007722603,0.00045399374,0.00012840092,0.00017225454,0.00018882188,0.0000061551964,0.0003103855,0.0002543151,0.000010634837],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012493518,0.0003838896,0.00002150913,0.009507081,0.0008575574,0.000057302394,0.00050899194,0.0000074762406,0.33079025,0.0005832789,0.00016378041,0.6569939],"study_design_scores_gemma":[0.00090657803,0.0004942204,0.0000017390934,0.009723884,0.00012355651,0.000034666504,0.00036015888,0.000020843177,0.48656777,0.0000052692,0.5004906,0.0012706785],"about_ca_topic_score_codex":0.000022161084,"about_ca_topic_score_gemma":0.000038312362,"teacher_disagreement_score":0.6557233,"about_ca_system_score_codex":0.000045991233,"about_ca_system_score_gemma":0.00026644015,"threshold_uncertainty_score":0.9997912},"labels":[],"label_agreement":null},{"id":"W2905539579","doi":"10.1038/s41598-018-36000-3","title":"Measuring Single-Cell Phenotypic Growth Heterogeneity Using a Microfluidic Cell Volume Sensor","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Phenotype; Biology; Cell; Saccharomyces cerevisiae; Phenotypic screening; Single-cell analysis; Population; Gene expression; Cell growth; Cell biology; Gene; Genetics","score_opus":0.029543726717975026,"score_gpt":0.2266372753971041,"score_spread":0.19709354867912907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2905539579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9811678,0.0011698726,0.011552274,0.000007730307,0.004842082,0.00019338285,0.0000037229956,0.000030503248,0.0010326294],"genre_scores_gemma":[0.9929562,0.000009004146,0.003900059,0.000047125952,0.0005153981,0.0000045386623,0.000055502183,0.000041712025,0.0024704542],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997621,0.000076645854,0.00044179385,0.0010261661,0.00034686923,0.0004875529],"domain_scores_gemma":[0.99837786,0.0000035625183,0.00027569634,0.0007692058,0.00040375275,0.00016992766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009094957,0.00022530118,0.00018874455,0.00009531084,0.00050163496,0.00024035515,0.00017889406,0.00015932151,0.00014115915],"category_scores_gemma":[0.000059453036,0.0002227339,0.0001516983,0.00021179138,0.00023173292,0.000011874999,0.0001651804,0.0000819175,0.000052588744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012824147,0.000084209365,0.002020239,0.00002349815,0.000012020839,0.00003475575,0.000065930886,0.000011596631,0.9952796,0.0000011696519,0.0023292229,0.00012493036],"study_design_scores_gemma":[0.00013939461,0.00011285258,0.00003721915,0.00001737376,0.000024517018,0.00013904175,0.00003939159,0.00012270345,0.9790572,0.00013220999,0.019907268,0.0002708217],"about_ca_topic_score_codex":0.000036932637,"about_ca_topic_score_gemma":0.000007601536,"teacher_disagreement_score":0.017578045,"about_ca_system_score_codex":0.000043587108,"about_ca_system_score_gemma":0.00013491361,"threshold_uncertainty_score":0.90828246},"labels":[],"label_agreement":null},{"id":"W2908077109","doi":"10.5772/intechopen.81343","title":"Adrenergic Receptors as Pharmacological Targets for Neuroinflammation and Neurodegeneration in Parkinson’s Disease","year":2019,"lang":"en","type":"book-chapter","venue":"IntechOpen eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"","keywords":"Neuroinflammation; Neurodegeneration; Parkinson's disease; Neuroscience; Disease; Medicine; Adrenergic receptor; Receptor; Psychology; Internal medicine","score_opus":0.015302279742738309,"score_gpt":0.25046103671416386,"score_spread":0.23515875697142555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2908077109","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6522411,0.00474469,0.008157374,0.00056385883,0.005591056,0.0104819555,0.0003199625,0.00016229415,0.3177377],"genre_scores_gemma":[0.61083573,0.00074970827,0.0007604646,0.0008067565,0.0008642851,0.00026713926,0.0009015424,0.00016623523,0.3846481],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986288,0.000037485093,0.00034711818,0.0006460535,0.00013282674,0.00020772585],"domain_scores_gemma":[0.99938667,0.00002119899,0.00017891759,0.00021409326,0.00007906575,0.000120082266],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018534854,0.0003158273,0.00026213814,0.00009687268,0.000061842155,0.000060732535,0.00017729419,0.00034374525,0.00019270195],"category_scores_gemma":[0.00005064596,0.00030578987,0.00013112921,0.0000069647426,0.000044950113,0.000005462948,0.0001330524,0.00020231525,0.000019466199],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008107221,0.000018406576,0.000027593202,0.000069702495,0.000060049726,0.000023701346,0.000029138251,0.0001967299,0.96070725,0.013199792,0.0018583521,0.022998556],"study_design_scores_gemma":[0.000841948,0.00048816376,0.0000152875,0.000084777275,0.000067382534,0.000009358072,0.0000053225817,0.0004706943,0.30748877,0.0039947443,0.6860397,0.0004938412],"about_ca_topic_score_codex":0.000006824327,"about_ca_topic_score_gemma":0.00002629172,"teacher_disagreement_score":0.68418133,"about_ca_system_score_codex":0.00002685863,"about_ca_system_score_gemma":0.0001274067,"threshold_uncertainty_score":0.99993944},"labels":[],"label_agreement":null},{"id":"W2908811796","doi":"10.1016/j.neuropharm.2019.01.018","title":"Shaky ground - The nature of metastable GPCR signalling complexes","year":2019,"lang":"en","type":"review","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Health Canada","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Allosteric regulation; Receptor; Metabotropic receptor; Computational biology; Signalling; Drug discovery; Neuroscience; Chemistry; Metabotropic glutamate receptor; Biology; Glutamate receptor; Cell biology; Biochemistry","score_opus":0.04869552260448316,"score_gpt":0.34767787453046356,"score_spread":0.2989823519259804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2908811796","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010433164,0.99603164,0.00012725788,0.000019835448,0.0016224124,0.0007244988,0.000089158384,0.000011530299,0.00033032466],"genre_scores_gemma":[0.0018270456,0.99573946,0.00011946655,0.00046870363,0.0006353605,0.00005472733,0.00020229245,0.000091676404,0.0008612604],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977043,0.00057066116,0.0005661389,0.0006001035,0.00018127533,0.00037747787],"domain_scores_gemma":[0.99870294,0.00020751689,0.0005011975,0.00042209408,0.00010251494,0.00006372731],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033926283,0.00042500044,0.0011846584,0.00008211899,0.00010568452,0.000025369232,0.0008206977,0.0006040595,0.0005770387],"category_scores_gemma":[0.000053167136,0.00028307302,0.0006066504,0.0001787526,0.000110374946,0.000003373692,0.00032757246,0.00083288277,0.00004428928],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009244064,0.00015115314,0.0000017349172,0.008854897,0.0014058136,0.000037883674,0.000024730745,0.00017876063,0.80402154,0.0009784248,0.008072864,0.17617974],"study_design_scores_gemma":[0.00022219095,0.00024947687,4.3250384e-7,0.00022350241,0.0009123686,0.000056336696,0.0000058120227,0.000015309719,0.016652646,0.000018605939,0.98139364,0.00024969163],"about_ca_topic_score_codex":0.000006802292,"about_ca_topic_score_gemma":0.0000012244981,"teacher_disagreement_score":0.9733208,"about_ca_system_score_codex":0.000014105043,"about_ca_system_score_gemma":0.00021468061,"threshold_uncertainty_score":0.99996215},"labels":[],"label_agreement":null},{"id":"W2909285114","doi":"10.1101/520965","title":"Causal evidence supporting the proposal that dopamine transients function as a <i>temporal difference</i> prediction error","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"Mean squared prediction error; Dopamine; Temporal difference learning; Psychology; Conditioning; Neuroscience; Function (biology); Blocking (statistics); Cognitive psychology; Computer science; Artificial intelligence; Machine learning; Mathematics; Biology; Statistics; Reinforcement learning","score_opus":0.019935369403791234,"score_gpt":0.2388519074357599,"score_spread":0.21891653803196867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2909285114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9744176,0.0013698066,0.019533498,0.00026156497,0.0028137148,0.0013243818,0.00014909705,0.00012354396,0.0000067622973],"genre_scores_gemma":[0.99728876,0.00027802528,0.0007867455,0.00029005672,0.00095391885,0.0002025556,0.000008776936,0.00012149816,0.000069646114],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99669546,0.00025496824,0.0005894008,0.0012490343,0.00059347565,0.000617638],"domain_scores_gemma":[0.99764025,0.000030842224,0.000592584,0.0011827218,0.0003594167,0.00019418343],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009131281,0.0006065856,0.0004442987,0.00008891102,0.00026425972,0.00024231951,0.00060992665,0.0007158716,0.000082829516],"category_scores_gemma":[0.00018260114,0.00049305416,0.0002578368,0.00018328833,0.00011536668,0.000025904885,0.00039351694,0.000708044,0.000038362516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019614893,0.000073365736,0.014192314,0.00020934516,0.0001461792,0.000008714251,0.000012672431,0.00016073942,0.98467916,0.00007225503,0.00024384166,0.000005281562],"study_design_scores_gemma":[0.00051379524,0.0005481207,0.022734808,0.00047731423,0.00022458423,1.8325062e-7,0.000016232589,0.0006054117,0.9710277,0.000005871958,0.0031774037,0.0006685924],"about_ca_topic_score_codex":0.000091786766,"about_ca_topic_score_gemma":0.0000099967965,"teacher_disagreement_score":0.022871146,"about_ca_system_score_codex":0.00007565488,"about_ca_system_score_gemma":0.00087846734,"threshold_uncertainty_score":0.9997521},"labels":[],"label_agreement":null},{"id":"W2910879024","doi":"10.1016/j.psychres.2019.01.032","title":"The effects of a muscarinic receptor 1 gene variant on executive and non-executive cognition in schizophrenia spectrum disorders","year":2019,"lang":"en","type":"article","venue":"Psychiatry Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Wisconsin Card Sorting Test; Schizophrenia spectrum; Schizophrenia (object-oriented programming); Muscarinic acetylcholine receptor; Single-nucleotide polymorphism; Cognition; Psychology; Executive functions; Executive dysfunction; Muscarinic acetylcholine receptor M1; Effects of sleep deprivation on cognitive performance; Clinical psychology; Neuroscience; Genotype; Psychosis; Psychiatry; Genetics; Gene; Receptor; Biology; Neuropsychology","score_opus":0.007559585920300508,"score_gpt":0.27462773895003206,"score_spread":0.2670681530297316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2910879024","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952889,0.001086272,0.00008717046,0.0004569331,0.0006000192,0.0007738238,0.000010714071,0.0000037027232,0.001692427],"genre_scores_gemma":[0.99738115,0.0016963506,0.0003162567,0.000029715771,0.00014085551,0.00006170574,0.00002632061,0.000022022732,0.0003256511],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99848133,0.00024580923,0.00020801347,0.00041146541,0.00028224988,0.0003711543],"domain_scores_gemma":[0.9993545,0.00015797686,0.00006718825,0.00030263982,0.00004925424,0.00006846867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007804394,0.00013457538,0.00015504715,0.00011461482,0.00013914244,0.00003094935,0.00019962156,0.00014133671,0.000024322344],"category_scores_gemma":[0.000099356985,0.000102920276,0.00006580456,0.00021295076,0.000117347074,0.000004685992,0.00012804441,0.00031573916,0.000021152273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027573586,0.00027841172,0.0071608466,0.00015952982,0.0001376146,0.0000017248792,0.0002250364,0.000011802192,0.98163486,0.0034614454,0.00099408,0.0031772954],"study_design_scores_gemma":[0.010154042,0.014138773,0.047411773,0.0008073279,0.00004584061,0.000013009955,0.0023321905,0.000561983,0.88821876,0.03165085,0.00381907,0.0008463665],"about_ca_topic_score_codex":0.00007139186,"about_ca_topic_score_gemma":0.00017163671,"teacher_disagreement_score":0.09341608,"about_ca_system_score_codex":0.000016199276,"about_ca_system_score_gemma":0.00012544963,"threshold_uncertainty_score":0.41969672},"labels":[],"label_agreement":null},{"id":"W2912709345","doi":"10.3389/fendo.2019.00022","title":"Teneurin C-Terminal Associated Peptide (TCAP)-1 and Latrophilin Interaction in HEK293 Cells: Evidence for Modulation of Intercellular Adhesion","year":2019,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"HEK 293 cells; Cell biology; Cytoskeleton; Intracellular; Biology; Extracellular; Transmembrane protein; Cell adhesion; G protein-coupled receptor; Receptor; Actin cytoskeleton; Adhesion; Chemistry; Signal transduction; Biochemistry; Cell","score_opus":0.01923561557217564,"score_gpt":0.2680232767948685,"score_spread":0.24878766122269283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912709345","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99216866,0.00065229216,0.006140313,0.000030217034,0.00065606006,0.00031477713,0.000003856692,0.0000044610697,0.000029363357],"genre_scores_gemma":[0.9954378,0.0005703356,0.0036639604,0.000022730233,0.000036602825,0.000024398147,0.00004280321,0.000014120908,0.00018723126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899817,0.00010286684,0.0002926749,0.00032550664,0.000058952704,0.00022182305],"domain_scores_gemma":[0.99963295,0.00003260757,0.00013035111,0.00014470998,0.00003684316,0.000022530408],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016585764,0.000115726194,0.00023317493,0.00015180281,0.000014055308,0.000006167485,0.000101858685,0.00013756701,0.000013643877],"category_scores_gemma":[0.00011234285,0.00012172871,0.000057293797,0.000074700765,0.000033066823,0.000014360069,0.00007793307,0.00010937209,0.000001090948],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039004328,0.000047799436,0.085331745,0.000049861843,0.000015668802,0.0000059570757,0.00010075649,0.0012884856,0.9095721,0.000012653197,0.00014973534,0.0030351826],"study_design_scores_gemma":[0.0023451815,0.0014527956,0.023984002,0.0003657088,0.000021306158,0.000025252064,0.0005282773,0.029825617,0.9393331,0.00083764875,0.0009683121,0.00031284516],"about_ca_topic_score_codex":0.000048034708,"about_ca_topic_score_gemma":0.000042944695,"teacher_disagreement_score":0.06134774,"about_ca_system_score_codex":0.000046614114,"about_ca_system_score_gemma":0.000015734753,"threshold_uncertainty_score":0.4963953},"labels":[],"label_agreement":null},{"id":"W2912805658","doi":"10.1002/chin.201119210","title":"ChemInform Abstract: Discovery of MK‐7246, a Selective CRTH2 Antagonist for the Treatment of Respiratory Diseases.","year":2011,"lang":"en","type":"article","venue":"ChemInform","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Chemistry; Antagonist; Combinatorial chemistry; Respiratory system; Stereochemistry; Pharmacology; Internal medicine; Biochemistry; Receptor","score_opus":0.021587686273469638,"score_gpt":0.25008335404882187,"score_spread":0.22849566777535224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912805658","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6559183,0.0072502997,0.00024023249,0.000031099073,0.0006311627,0.002497432,0.0010894594,0.000038947972,0.33230308],"genre_scores_gemma":[0.9959269,0.00034379633,0.00006447997,0.000044202436,0.00015474232,0.00012275808,0.00010631112,0.000020005338,0.0032168126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916,1.2978113e-7,0.00033879778,0.00017863151,0.00011311467,0.00020932291],"domain_scores_gemma":[0.9991871,0.000033073393,0.00025421497,0.00034034412,0.00012904983,0.00005622511],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008482087,0.00017631578,0.00021968698,0.00002454157,0.00006990727,0.000011612315,0.00019375095,0.00011978119,0.00009406103],"category_scores_gemma":[0.000036292313,0.00011920955,0.00026551366,0.00006029662,0.00012639159,0.000014346936,0.000032425745,0.000033454435,0.0000010875037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010271206,0.00048606884,0.00034163403,0.00018810808,0.00043212748,9.709763e-7,0.0017863407,0.0000011761769,0.7951506,0.00044330404,0.0038936515,0.19624895],"study_design_scores_gemma":[0.000703988,0.0007865978,0.00075414695,0.000014873331,0.00007428186,0.0000013709337,0.00047502108,0.000003604985,0.966925,0.00007321959,0.030050185,0.00013770728],"about_ca_topic_score_codex":0.000038921993,"about_ca_topic_score_gemma":0.000008319792,"teacher_disagreement_score":0.3400086,"about_ca_system_score_codex":0.00003392431,"about_ca_system_score_gemma":0.0001435382,"threshold_uncertainty_score":0.48612243},"labels":[],"label_agreement":null},{"id":"W2916025068","doi":"","title":"Spatiotemporal coordination of excitation and inhibition mediated by starburst amacrine cells","year":2018,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Excitation; Neuroscience; Amacrine cell; Chemistry; Physics; Biology; Retina; Quantum mechanics","score_opus":0.01787326136093703,"score_gpt":0.2978318572703166,"score_spread":0.27995859590937955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916025068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990586,0.000060697927,0.00028245972,0.00010071193,0.00013458464,0.00014347782,0.000019177343,0.000006200453,0.00019407558],"genre_scores_gemma":[0.9983251,0.000007139005,0.0013629495,0.00007689544,0.000063882275,0.000008360337,0.000085047184,0.000007799419,0.00006282175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896175,0.000090179674,0.0002044273,0.00036436913,0.0001919187,0.00018734588],"domain_scores_gemma":[0.99924815,0.000022947639,0.00017649516,0.000091010865,0.00035282254,0.00010860225],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004918992,0.00011117359,0.00011730255,0.000080964564,0.00015709751,0.00001822134,0.00009795507,0.00009407455,0.000056843743],"category_scores_gemma":[0.00025160194,0.000106286345,0.000017736016,0.0003014371,0.0023956513,0.000026635766,0.000083950654,0.000055984056,0.0000044049516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020892603,0.000030190571,0.0016412132,0.000005947956,0.000005488772,0.0000014238167,0.00018472422,0.000001633503,0.9977861,0.0000742,0.00010132725,0.00014688131],"study_design_scores_gemma":[0.00024186025,0.0013480989,0.004158002,0.0000143673215,0.000004635813,0.000009828173,0.00014237799,0.0004890051,0.99207574,0.0013430812,0.00006123082,0.0001117682],"about_ca_topic_score_codex":0.00007171167,"about_ca_topic_score_gemma":0.0000033717245,"teacher_disagreement_score":0.0057103327,"about_ca_system_score_codex":0.000017726692,"about_ca_system_score_gemma":0.00010340695,"threshold_uncertainty_score":0.8826877},"labels":[],"label_agreement":null},{"id":"W2916801054","doi":"","title":"Conformational flexibility of the arrestin-rhodopsin complex.","year":2018,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Rhodopsin; Arrestin; Flexibility (engineering); Chemistry; Biophysics; Biology; G protein-coupled receptor; Mathematics; Biochemistry; Retinal; Receptor","score_opus":0.06358644500562029,"score_gpt":0.35124106314205433,"score_spread":0.28765461813643406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916801054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957296,0.0000149088355,0.00008846678,0.0001200712,0.00033240396,0.00015649221,0.00001209872,0.0000054010425,0.003540546],"genre_scores_gemma":[0.9969278,4.29864e-7,0.0025262658,0.0002712407,0.00012659142,0.000007294069,0.000008513299,0.000005462238,0.00012643245],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987082,0.00013770939,0.00025712847,0.00034442914,0.00028844472,0.0002641181],"domain_scores_gemma":[0.99897903,0.000030504842,0.00019018834,0.00027974174,0.0004130624,0.00010744479],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00082858,0.000120831115,0.00013002634,0.000037221045,0.0003691635,0.000018535671,0.0005696796,0.000081922,0.0002814589],"category_scores_gemma":[0.0006979386,0.000085776126,0.000058340655,0.00037427113,0.007357183,0.000014269816,0.0003172142,0.000086796084,0.000015251077],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017160188,0.000026390853,0.00796413,0.000003700972,0.0000064998844,5.0517093e-7,0.0001525805,0.00002577623,0.9908767,0.0007717397,0.00005869371,0.00009612367],"study_design_scores_gemma":[0.000123327,0.00041621877,0.06196574,0.000010996627,0.0000036130477,0.000048420487,0.000089847556,0.00058868865,0.9323966,0.0039916616,0.00026870452,0.00009616516],"about_ca_topic_score_codex":0.00003462237,"about_ca_topic_score_gemma":0.0000031083657,"teacher_disagreement_score":0.058480084,"about_ca_system_score_codex":0.00002021308,"about_ca_system_score_gemma":0.0004119637,"threshold_uncertainty_score":0.9953442},"labels":[],"label_agreement":null},{"id":"W2916935088","doi":"10.1111/bph.14635","title":"Cardiac β<sub>3</sub>‐adrenoceptors—A role in human pathophysiology?","year":2019,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Astellas Pharma Canada; Deutsche Forschungsgemeinschaft; Ankara Universitesi","keywords":"Inotrope; Heart failure; Pathophysiology; Diabetes mellitus; Internal medicine; Medicine; Endocrinology; Agonism; Pathological; Adrenergic receptor; Bioinformatics; Cardiology; Biology; Receptor","score_opus":0.015216631691538647,"score_gpt":0.3008391224855482,"score_spread":0.2856224907940096,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2916935088","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.046825882,0.9501086,0.000024004676,0.000005574293,0.0024683413,0.00040325566,0.00007712848,0.000004914635,0.0000822845],"genre_scores_gemma":[0.003930057,0.9930978,0.000079057834,0.00012532601,0.0024058854,0.000029875204,0.00016946705,0.00009003705,0.000072508425],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969142,0.0007833013,0.0011541599,0.00047055297,0.00018414977,0.0004936462],"domain_scores_gemma":[0.9985123,0.000047675207,0.0009968663,0.0001388944,0.00016811155,0.00013609973],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00074034906,0.00039669967,0.001972406,0.00022992943,0.000078073295,0.000039011422,0.00057431974,0.00079135934,0.00023518191],"category_scores_gemma":[0.00003922109,0.0004355839,0.0010644491,0.00015962623,0.00007937973,0.000009514026,0.00019801487,0.0009703133,0.000028317178],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014779843,0.00007436954,0.0000015941469,0.00067945174,0.00027361498,0.00015813737,0.000006405407,0.000010511618,0.59788746,0.0000032615599,0.0057951803,0.39509523],"study_design_scores_gemma":[0.0009088684,0.0006408162,0.0000050290755,0.0022836523,0.0007526768,0.00095536024,0.000021505419,0.0000011420873,0.14987053,0.000087124325,0.84392786,0.000545428],"about_ca_topic_score_codex":0.000011643588,"about_ca_topic_score_gemma":0.000005102629,"teacher_disagreement_score":0.8381327,"about_ca_system_score_codex":0.00008585356,"about_ca_system_score_gemma":0.00042448318,"threshold_uncertainty_score":0.9998096},"labels":[],"label_agreement":null},{"id":"W2921175534","doi":"10.1016/j.isci.2019.03.011","title":"Biased Signaling of the Mu Opioid Receptor Revealed in Native Neurons","year":2019,"lang":"en","type":"article","venue":"iScience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Douglas Mental Health University Institute; Douglas College; Institute for Research in Immunology and Cancer; McGill University","funders":"European Regional Development Fund; Canadian Institutes of Health Research; National Institute on Drug Abuse; Agence Nationale de la Recherche; Canada Research Chairs; National Institutes of Health; Canada Foundation for Innovation","keywords":"Receptor; Drug discovery; Opioid; Pharmacology; Opioid receptor; Computational biology; Signal transduction; Drug; Neuroscience; Chemistry; Cell biology; Biology; Bioinformatics; Biochemistry","score_opus":0.010807719009322746,"score_gpt":0.23697262035226502,"score_spread":0.22616490134294226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921175534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982346,0.0001555571,0.00033857278,0.00006891099,0.0003111589,0.00017273509,0.0000060490797,0.00000264545,0.00070971355],"genre_scores_gemma":[0.9986964,0.00001633269,0.0005458925,0.00015105824,0.000030133846,0.00000509618,0.0000023400949,0.0000058949186,0.00054688787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999245,0.00006487706,0.00014761872,0.00023822919,0.00015175012,0.00015256662],"domain_scores_gemma":[0.99959695,0.000021178288,0.000082727565,0.00022792607,0.000045077115,0.00002616008],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029659286,0.00007022333,0.000089120236,0.000029307666,0.00004119013,0.000010153051,0.0003230261,0.000048595073,0.000107587606],"category_scores_gemma":[0.00012024404,0.000049893908,0.00005461473,0.00022742095,0.000068569876,0.000004512576,0.00009873375,0.000069599126,0.000007912197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009074919,0.000013963206,0.0034662655,0.0000056678496,0.0000015697741,1.5081339e-7,0.0001282175,0.00041066544,0.99536705,0.00011174792,0.000052560812,0.0004330869],"study_design_scores_gemma":[0.00018262178,0.00009460878,0.001664033,0.000036965826,0.0000013608515,8.983961e-7,0.0001609254,0.00027810025,0.9959344,0.000074821204,0.0014981497,0.00007308347],"about_ca_topic_score_codex":0.000018676506,"about_ca_topic_score_gemma":0.000008463852,"teacher_disagreement_score":0.0018022325,"about_ca_system_score_codex":0.000008566191,"about_ca_system_score_gemma":0.00007990725,"threshold_uncertainty_score":0.20346145},"labels":[],"label_agreement":null},{"id":"W2921338596","doi":"10.3389/fendo.2019.00162","title":"Asymmetric Recruitment of β-Arrestin1/2 by the Angiotensin II Type I and Prostaglandin F2α Receptor Dimer","year":2019,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University; University of Missouri","keywords":"Receptor; Angiotensin II; G protein-coupled receptor; Cell biology; HEK 293 cells; Chemistry; Dimer; Internal medicine; Prostaglandin; Biology; Endocrinology; Biochemistry; Medicine","score_opus":0.012938207421125279,"score_gpt":0.23958032690908426,"score_spread":0.22664211948795898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2921338596","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98309326,0.013009637,0.0010195954,0.00031401712,0.0015687523,0.00058115553,0.000018171286,0.000007631264,0.0003877868],"genre_scores_gemma":[0.9923851,0.0017781068,0.0036284465,0.00018323383,0.000068720066,0.000028130691,0.00008631373,0.000020390515,0.001821545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990377,0.000089213296,0.00020223073,0.00029907067,0.000082129125,0.0002896977],"domain_scores_gemma":[0.9995567,0.000015901513,0.00008862016,0.00024961165,0.00005406063,0.000035110686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001301678,0.0001291775,0.00021530966,0.00009074522,0.000045564422,0.0000060667135,0.00015172017,0.00011966022,0.000039443086],"category_scores_gemma":[0.00006449093,0.0000968889,0.000036682668,0.00020717403,0.00006224759,0.0000031452275,0.00014349759,0.00012020014,0.0000051903967],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027876615,0.00008639481,0.054796584,0.000018624316,0.00011685969,0.0000024621802,0.00015243026,0.0000392066,0.8057825,0.00034602752,0.11718352,0.021196626],"study_design_scores_gemma":[0.0012577599,0.0012390367,0.0017041138,0.000019896037,0.000021337153,0.000025159658,0.0003171325,0.00017809996,0.53750515,0.00018825181,0.45730427,0.00023981114],"about_ca_topic_score_codex":0.000035257806,"about_ca_topic_score_gemma":0.0000032592577,"teacher_disagreement_score":0.34012076,"about_ca_system_score_codex":0.000015885309,"about_ca_system_score_gemma":0.000029446157,"threshold_uncertainty_score":0.3951015},"labels":[],"label_agreement":null},{"id":"W2922095699","doi":"10.1161/atvb.38.suppl_1.624","title":"Abstract 624: Interactions Between Adenylate Cyclase Type 9 (ADCY9) and Cholesteryl Ester Transfer Protein (CETP) in Atherosclerosis","year":2018,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Cholesterylester transfer protein; Endocrinology; Internal medicine; Chemistry; Adipose tissue; Cholesterol; Lipoprotein; Medicine","score_opus":0.04030537361995412,"score_gpt":0.29325821964057597,"score_spread":0.25295284602062185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2922095699","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978092,0.00008011565,0.0012929502,0.00017236132,0.00017567468,0.0003499623,0.000031415886,0.000021288728,0.00006703252],"genre_scores_gemma":[0.997759,0.0009533736,0.00056033785,0.00023595766,0.00030314244,0.000053249227,0.000076497294,0.00004571003,0.000012719593],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9982544,0.00013028842,0.00040410724,0.0007030631,0.000084117375,0.00042399688],"domain_scores_gemma":[0.99933887,0.000019844148,0.00006567335,0.0003523237,0.000073639465,0.00014966453],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00031614306,0.00031727276,0.0004058891,0.00010721752,0.00018751468,0.00009119711,0.00015568986,0.0003134145,0.00016776484],"category_scores_gemma":[0.000022183247,0.00028574758,0.00012374023,0.00012974348,0.00027427392,0.00002852976,0.00012208514,0.0001817559,0.00001752369],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000094839315,0.00006206552,0.056043934,0.000018762814,0.00011696491,3.5454477e-8,0.00020572441,0.0000010570838,0.94252026,0.000044854885,0.00001913022,0.0009577507],"study_design_scores_gemma":[0.0011771518,0.0008829295,0.883854,0.0001619879,0.000059190144,9.070024e-7,0.00013241843,0.00004417418,0.1092046,0.000056127054,0.0039618006,0.00046473986],"about_ca_topic_score_codex":0.00007356682,"about_ca_topic_score_gemma":0.00019369149,"teacher_disagreement_score":0.8333156,"about_ca_system_score_codex":0.000015315516,"about_ca_system_score_gemma":0.00002199479,"threshold_uncertainty_score":0.99995947},"labels":[],"label_agreement":null},{"id":"W2923377589","doi":"10.1007/978-1-4939-9158-7_2","title":"β-Arrestins: Multitask Scaffolds Orchestrating the Where and When in Cell Signalling","year":2019,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; Agence Nationale de la Recherche","keywords":"Scaffold protein; G protein-coupled receptor; Biology; Cell biology; Signalling; Signal transducing adaptor protein; Signal transduction; Endocytosis; Compartmentalization (fire protection); Neuroscience; Receptor; Genetics","score_opus":0.05288364077229508,"score_gpt":0.4015967133740045,"score_spread":0.3487130726017094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2923377589","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00045943054,0.8757139,0.12252015,0.000015377367,0.0002582356,0.00079369394,0.000011551673,0.000008517414,0.00021915585],"genre_scores_gemma":[0.000043930086,0.6968556,0.30253327,0.000078761776,0.00010450728,0.00012353972,0.00008420646,0.000070528855,0.000105663035],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9944786,0.003030574,0.0008320678,0.0010079668,0.000092461625,0.000558334],"domain_scores_gemma":[0.9985773,0.00036760472,0.00036018674,0.0005858766,0.00003895859,0.0000700706],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0027375882,0.00056076463,0.0012486487,0.00019005836,0.00006070366,0.000050598454,0.00060608354,0.001104547,0.00003368209],"category_scores_gemma":[0.0003026164,0.00040839243,0.0003103159,0.0002217671,0.00013200488,0.0000034028353,0.00039964213,0.00053107715,0.000005683862],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010260535,0.000039793533,0.000050060684,0.0024550334,0.000074835705,0.000024108389,0.000085372376,0.0000688181,0.42084998,0.0002710475,0.000015374168,0.5760553],"study_design_scores_gemma":[0.0010976976,0.0006218426,0.0000021816543,0.0052754185,0.00039074678,0.00009917018,0.00024956785,0.00053772883,0.063028485,0.0029659576,0.92398536,0.0017458197],"about_ca_topic_score_codex":0.000097013224,"about_ca_topic_score_gemma":0.000049129794,"teacher_disagreement_score":0.92397,"about_ca_system_score_codex":0.0000398406,"about_ca_system_score_gemma":0.0002212256,"threshold_uncertainty_score":0.9998368},"labels":[],"label_agreement":null},{"id":"W2925793627","doi":"10.1007/978-1-4939-9158-7_5","title":"Measuring Recruitment of β-Arrestin to G Protein-Coupled Heterodimers Using Bioluminescence Resonance Energy Transfer","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Bioluminescence; Energy transfer; Resonance (particle physics); Biophysics; Materials science; Chemistry; Physics; Biology; Chemical physics; Atomic physics; Biochemistry","score_opus":0.0637547849459446,"score_gpt":0.3571130341071689,"score_spread":0.29335824916122427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2925793627","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4907409,0.00079430075,0.5078672,0.000014932331,0.00015272279,0.00038331017,0.0000032843159,0.0000048899005,0.000038458867],"genre_scores_gemma":[0.5061203,0.000031274536,0.4934549,0.0001621132,0.000033246946,0.00009292325,0.000013481868,0.000032010692,0.000059701197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99764526,0.0007102665,0.00045825157,0.000662552,0.0001094377,0.00041425056],"domain_scores_gemma":[0.99924785,0.000025815472,0.000077054465,0.00047518677,0.00008849974,0.000085612926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010648675,0.00024140456,0.0003980387,0.0001507731,0.000028124083,0.000007736839,0.0003191131,0.0002665153,0.000038158138],"category_scores_gemma":[0.0001622502,0.00023449417,0.00013791112,0.0002704328,0.00006213085,0.0000030444328,0.00012728531,0.00010929084,0.0000019313545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013700363,0.00003717585,0.00069844024,0.00002400345,0.000026187952,0.0000035336996,0.000035452642,0.00063495134,0.9888926,0.00087217125,6.552857e-7,0.008637826],"study_design_scores_gemma":[0.00047118525,0.00045379304,0.000049063477,0.000090492904,0.000008566646,0.000006046764,0.000025540641,0.0010188645,0.9948376,0.00021686191,0.0025521857,0.00026984146],"about_ca_topic_score_codex":0.00018030235,"about_ca_topic_score_gemma":0.000018958091,"teacher_disagreement_score":0.0153794475,"about_ca_system_score_codex":0.000033926048,"about_ca_system_score_gemma":0.00007108757,"threshold_uncertainty_score":0.9562395},"labels":[],"label_agreement":null},{"id":"W2929013716","doi":"10.1007/978-1-4939-9158-7_10","title":"Methods to Investigate the β-Arrestin-Mediated Control of ARF6 Activation to Regulate Trafficking and Actin Cytoskeleton Remodeling","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; RAC1; Arrestin; GTPase; RHOA; Actin cytoskeleton; ADP ribosylation factor; Cytoskeleton; Receptor; Stimulation; Actin; Small GTPase; G protein-coupled receptor; Chemistry; Biology; Signal transduction; Neuroscience; Biochemistry; Cell","score_opus":0.016673742859806828,"score_gpt":0.358372746887648,"score_spread":0.34169900402784115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2929013716","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4655866,0.00016851483,0.53341055,0.00029812573,0.00012000486,0.00037199858,0.000002495594,0.000007201132,0.00003448395],"genre_scores_gemma":[0.41592413,0.000014696827,0.582887,0.0010436904,0.000037043657,0.000030867857,0.000014880068,0.000025605781,0.000022089936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99664086,0.0018812496,0.00045644693,0.00057994324,0.00008718685,0.00035430404],"domain_scores_gemma":[0.9988483,0.00032329894,0.00017364514,0.0004479894,0.000089554465,0.0001171935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0033175016,0.00022755087,0.0003997697,0.00016555522,0.00004894198,0.00001691851,0.00027759417,0.0002877961,0.000014176052],"category_scores_gemma":[0.0016541836,0.0001823632,0.00008549999,0.00031362651,0.00006617441,0.000004351241,0.000166888,0.00020105962,0.0000020245043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014108971,0.000011468392,0.00031513182,0.0000151432605,0.000036631365,5.6237775e-7,0.00018471852,0.0072032996,0.9535191,0.0003982226,0.0000040381397,0.03817056],"study_design_scores_gemma":[0.0005460215,0.0003661193,0.00020439601,0.0000474353,0.000015767977,0.0000053074855,0.000103231214,0.005883822,0.98788637,0.0013062904,0.003416829,0.00021840447],"about_ca_topic_score_codex":0.000045601835,"about_ca_topic_score_gemma":0.0000054663715,"teacher_disagreement_score":0.049662482,"about_ca_system_score_codex":0.000020095129,"about_ca_system_score_gemma":0.00005646202,"threshold_uncertainty_score":0.74365556},"labels":[],"label_agreement":null},{"id":"W2929346300","doi":"10.1007/978-1-4939-9158-7_3","title":"Methods to Monitor the Trafficking of β-Arrestin/G Protein-Coupled Receptor Complexes Using Enhanced Bystander BRET","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Arrestin; Endosome; G protein-coupled receptor; Cell biology; Receptor; Chemistry; Bystander effect; Biology; Biochemistry","score_opus":0.025874225044657653,"score_gpt":0.3901087925170994,"score_spread":0.36423456747244176,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2929346300","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4587992,0.00045026894,0.5397827,0.0000369194,0.0002994386,0.0005633612,0.0000050828817,0.000008211128,0.00005480652],"genre_scores_gemma":[0.32348442,0.000009142088,0.6761154,0.00015604765,0.00007607915,0.000054554414,0.000017103948,0.00003779829,0.000049464514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99592173,0.0022181468,0.0005880745,0.0006614062,0.00012549949,0.0004851327],"domain_scores_gemma":[0.9987258,0.00016203208,0.00024255137,0.00064318994,0.00014255097,0.00008391349],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0028304604,0.00030130375,0.0005377881,0.0001354258,0.0000705377,0.000020464922,0.00052165956,0.0003422611,0.00014792717],"category_scores_gemma":[0.0005764651,0.00023526861,0.0001952041,0.00035316398,0.0001186796,0.000003924257,0.00025719457,0.00023291925,0.000004036996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013917581,0.000034437417,0.00008544532,0.000028295079,0.00006680247,8.0586756e-7,0.00015071435,0.0020168063,0.98590136,0.0008041142,0.0000043153627,0.0107677495],"study_design_scores_gemma":[0.0004867669,0.0004008511,0.000028853248,0.000057409554,0.000017526301,0.000005374888,0.00022992061,0.001909546,0.994284,0.0010183953,0.0012683922,0.0002929929],"about_ca_topic_score_codex":0.00006721588,"about_ca_topic_score_gemma":0.000006023804,"teacher_disagreement_score":0.13633268,"about_ca_system_score_codex":0.000035482557,"about_ca_system_score_gemma":0.00007315911,"threshold_uncertainty_score":0.95939755},"labels":[],"label_agreement":null},{"id":"W2932590068","doi":"10.1007/978-1-4939-9158-7_11","title":"Methods to Investigate the Roles of β-Arrestin-Dependent RalGDS Activation in GPCR-Stimulated Membrane Blebbing","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Arrestin; Cell biology; G protein-coupled receptor; Chemistry; Biophysics; Biology; Signal transduction","score_opus":0.020660430302344036,"score_gpt":0.3738959825817201,"score_spread":0.35323555227937603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2932590068","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5166461,0.00021904563,0.48231235,0.00014486157,0.00016511475,0.00034694758,0.0000018020862,0.000006462814,0.0001573289],"genre_scores_gemma":[0.411402,0.000021838432,0.58787835,0.00048846344,0.000029371682,0.000061256076,0.000027417997,0.000029520634,0.00006180447],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99569106,0.0026637162,0.0005693056,0.00057855435,0.000107389,0.00038999665],"domain_scores_gemma":[0.99888897,0.0002248134,0.0001864541,0.00054810377,0.00007945911,0.0000721937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0037838055,0.0002455815,0.0004339219,0.0002229922,0.000032047512,0.000013709301,0.0004419616,0.0003553342,0.0000818662],"category_scores_gemma":[0.001010683,0.00019528581,0.00011238878,0.0004310385,0.00007841612,0.0000048593224,0.00027080774,0.00027040867,0.0000039542006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010338298,0.000030710555,0.0011056407,0.000020165107,0.000038141585,0.000001688059,0.00016983383,0.013152304,0.9713544,0.0008966511,0.000003139995,0.0131239],"study_design_scores_gemma":[0.00061621645,0.00025634834,0.00021224319,0.0000487008,0.0000106813295,0.000003807286,0.00012364256,0.002282844,0.9922296,0.002988048,0.0010046219,0.00022324777],"about_ca_topic_score_codex":0.000110110006,"about_ca_topic_score_gemma":0.000030449246,"teacher_disagreement_score":0.10556599,"about_ca_system_score_codex":0.000031832013,"about_ca_system_score_gemma":0.00007791845,"threshold_uncertainty_score":0.79635245},"labels":[],"label_agreement":null},{"id":"W2937155927","doi":"10.1007/978-1-4939-9121-1_16","title":"Monitoring the Aggregation of GPCRs by Fluorescence Microscopy","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"G protein-coupled receptor; Aggresome; Endoplasmic reticulum; Cytoplasm; Protein aggregation; Cell biology; Biophysics; Chemistry; Protein folding; Dynein; Fluorescence microscope; Microtubule; Fluorescence; Biology; Biochemistry; Ubiquitin; Signal transduction","score_opus":0.010786947962980502,"score_gpt":0.35659058491841733,"score_spread":0.3458036369554368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937155927","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.59283286,0.0022037977,0.40424523,0.00004305157,0.00036157318,0.0001754727,0.000003848354,0.0000038028215,0.00013035868],"genre_scores_gemma":[0.47608694,0.00035462325,0.5232118,0.00008449307,0.000054663054,0.000024631961,0.0000250233,0.000022489767,0.00013537046],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986179,0.00054570363,0.0002509376,0.00031049128,0.00005949899,0.00021550975],"domain_scores_gemma":[0.9994088,0.000047551515,0.00011453051,0.00035734163,0.000046601308,0.000025219872],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008660516,0.00012548604,0.00017922698,0.000040691204,0.000026108888,0.000007661773,0.00029111977,0.00019724187,0.000031137937],"category_scores_gemma":[0.00014102689,0.00009681015,0.00008041414,0.00012419585,0.00007887691,0.0000018847209,0.000103077,0.000120881,0.0000033092965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024031653,0.000015018221,0.0059929024,0.000009056644,0.000017109818,3.8967448e-7,0.000031066877,0.000043663258,0.9805523,0.0002698684,0.000018376095,0.013026213],"study_design_scores_gemma":[0.0002273089,0.00016869472,0.00010651413,0.000022137838,0.0000052082178,0.000002623643,0.00005893086,0.00007713682,0.9961594,0.0007429707,0.0023214044,0.000107670574],"about_ca_topic_score_codex":0.00003282669,"about_ca_topic_score_gemma":6.025581e-7,"teacher_disagreement_score":0.118966535,"about_ca_system_score_codex":0.000010700985,"about_ca_system_score_gemma":0.000026935742,"threshold_uncertainty_score":0.39478034},"labels":[],"label_agreement":null},{"id":"W2937318362","doi":"10.1007/978-1-4939-9121-1_14","title":"Measurement of β-Arrestin Recruitment at GPCRs Using the Tango Assay","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Arrestin; Functional selectivity; G protein; Signal transduction; Receptor; Computational biology; Biology; Cell biology; Intracellular; HEK 293 cells; Chemistry; Biochemistry","score_opus":0.08277844592996782,"score_gpt":0.39805094215316905,"score_spread":0.31527249622320125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937318362","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3743279,0.0022192714,0.62210256,0.00006114969,0.00039701615,0.00050760794,0.0000034548525,0.0000045338024,0.00037651163],"genre_scores_gemma":[0.4397254,0.000082371764,0.5595236,0.00033401727,0.00006831846,0.00007161165,0.000020119129,0.000039342816,0.0001352295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99717265,0.0015796057,0.00036883718,0.00041865985,0.00015291208,0.00030732722],"domain_scores_gemma":[0.9991085,0.000044346016,0.0001735637,0.00053208927,0.000099494515,0.00004203984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0035533276,0.00018180908,0.00027966293,0.00006413802,0.000042253443,0.0000061720543,0.00030409158,0.0002281717,0.0001109356],"category_scores_gemma":[0.0003058051,0.00013376729,0.0001443824,0.00013886712,0.00008214764,0.00000128351,0.00025600384,0.00012377626,0.0000038910243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004652639,0.000028104832,0.0023528014,0.0000134838565,0.000055147735,0.0000017348029,0.00002941321,0.00070507766,0.99139595,0.0005656808,0.000014165741,0.004791925],"study_design_scores_gemma":[0.00036915907,0.00022419241,0.000095098905,0.000027371307,0.000017930608,0.00001020935,0.000051568524,0.00058047683,0.9878709,0.0006419713,0.009952204,0.00015893996],"about_ca_topic_score_codex":0.00004574534,"about_ca_topic_score_gemma":0.000014627996,"teacher_disagreement_score":0.065397486,"about_ca_system_score_codex":0.00007324313,"about_ca_system_score_gemma":0.000068354646,"threshold_uncertainty_score":0.54548717},"labels":[],"label_agreement":null},{"id":"W2937428609","doi":"10.1038/s41589-019-0270-1","title":"Chemogenetics defines receptor-mediated functions of short chain free fatty acids","year":2019,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council","keywords":"G protein-coupled receptor; Receptor; Free fatty acid receptor 1; Lipolysis; Enteroendocrine cell; Cell biology; Fatty acid; Biology; Biochemistry; Chemistry; Adipose tissue; Endocrine system","score_opus":0.005922165671802555,"score_gpt":0.22941244260706248,"score_spread":0.2234902769352599,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2937428609","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99473375,0.002135586,0.00062159635,0.00016367486,0.0006955253,0.00019189538,0.00016697055,0.000023815124,0.0012671584],"genre_scores_gemma":[0.9947453,0.00022603576,0.0025831284,0.00035141438,0.00036689063,0.00001563176,0.0015183528,0.000027837485,0.00016541046],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873984,0.00004280441,0.00030297154,0.00048665146,0.00011047684,0.00031726743],"domain_scores_gemma":[0.9991105,0.00004588317,0.00008420274,0.00053119595,0.00013133454,0.00009689335],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0001335109,0.00022216598,0.00030930017,0.000040353145,0.000027812786,0.0000057003836,0.00040251712,0.0013528474,0.0003508477],"category_scores_gemma":[0.0003261292,0.00019055694,0.00017002437,0.00015820349,0.000113561306,0.000002246644,0.00022445,0.00039468633,0.000028924502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009165404,0.0000500488,0.009865135,0.000019374174,0.00006729301,2.1327692e-7,0.000006813391,0.0000034374423,0.98749375,0.00033680338,0.0011903979,0.0008750787],"study_design_scores_gemma":[0.0004395081,0.00022416224,0.00021402328,0.000009934298,0.000013647522,0.000005642612,0.000023349457,0.000021196392,0.96664417,0.00018164805,0.032008175,0.00021453692],"about_ca_topic_score_codex":0.0000030322913,"about_ca_topic_score_gemma":0.0000014995392,"teacher_disagreement_score":0.030817777,"about_ca_system_score_codex":0.000011955451,"about_ca_system_score_gemma":0.000051593575,"threshold_uncertainty_score":0.9999436},"labels":[],"label_agreement":null},{"id":"W2938938320","doi":"10.1016/j.cell.2015.08.045","title":"Structural Insights into the Dynamic Process of β2-Adrenergic Receptor Signaling","year":2015,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Context (archaeology); Scopus; Receptor; Nuclear magnetic resonance spectroscopy; Biology; G protein-coupled receptor; Biophysics; Stereochemistry; Chemistry; Biochemistry; MEDLINE","score_opus":0.009433383656503777,"score_gpt":0.2369940293657141,"score_spread":0.2275606457092103,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2938938320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956994,0.002402497,0.00082132936,0.000023648363,0.00029145108,0.000099040444,0.0000016024891,0.000007746665,0.0006532885],"genre_scores_gemma":[0.99860686,0.000046314282,0.00062436925,0.00005747024,0.00013664635,0.0000080080945,0.00005759839,0.000018250317,0.0004444531],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992659,0.000048835667,0.00018154725,0.00021202776,0.00014750366,0.00014416539],"domain_scores_gemma":[0.99945384,0.0000076355445,0.00010488632,0.00021941337,0.00014028246,0.00007396488],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001303174,0.000121162484,0.000118457174,0.000023062059,0.000065804554,0.000016156495,0.00024822543,0.00010226304,0.00005267253],"category_scores_gemma":[0.000024973342,0.0000806552,0.000063996515,0.000085060456,0.000054969827,0.0000039002293,0.0000599612,0.00007324747,0.0000075194916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030817813,0.0000103015445,0.000035000117,0.000020757543,0.00001181357,4.326724e-7,0.0011492083,0.0018835863,0.99625605,0.000041288786,0.000105757965,0.0004549548],"study_design_scores_gemma":[0.00028157278,0.00015313328,0.000007729293,0.00001026918,0.000010557379,0.0000013350424,0.0010549146,0.001246564,0.99380124,0.00091795385,0.002392161,0.00012258117],"about_ca_topic_score_codex":0.000021233203,"about_ca_topic_score_gemma":0.0000114391105,"teacher_disagreement_score":0.0029074939,"about_ca_system_score_codex":0.000011708325,"about_ca_system_score_gemma":0.00008933253,"threshold_uncertainty_score":0.32890236},"labels":[],"label_agreement":null},{"id":"W2939195505","doi":"10.1007/978-1-4939-9121-1_9","title":"Combining Conformational Profiling of GPCRs with CRISPR/Cas9 Gene Editing Approaches","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Faculty of Medicine, McGill University","keywords":"CRISPR; G protein-coupled receptor; Genome editing; Computational biology; Cas9; Cell signaling; Biology; Signal transduction; Chemistry; Gene; Cell biology; Genetics","score_opus":0.028656655900557312,"score_gpt":0.33206099135315365,"score_spread":0.3034043354525963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939195505","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.41714144,0.00019165254,0.58143353,0.000016576607,0.00012865064,0.00018923313,0.0000051386746,0.000005592084,0.00088815053],"genre_scores_gemma":[0.3639668,0.000008435735,0.6357105,0.00008491393,0.000044071614,0.00002317876,0.0001230377,0.000018180948,0.000020894095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99846554,0.00040433535,0.00038030196,0.0003628543,0.00009649518,0.0002904608],"domain_scores_gemma":[0.9993448,0.00005024677,0.0002075782,0.00027455855,0.00008008344,0.000042735046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012048404,0.00017802356,0.00031289473,0.0001059241,0.00003139855,0.000009701445,0.00020490722,0.00023150459,0.000039946248],"category_scores_gemma":[0.00012597433,0.00015388102,0.00008117936,0.00013426362,0.00008592545,0.0000049518535,0.00011584279,0.00013027411,0.0000021297776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058843845,0.000025973744,0.0049136686,0.000036659298,0.00005272366,0.0000017725666,0.0000672093,0.0015150079,0.9839233,0.0071357936,0.0000015259928,0.0022674934],"study_design_scores_gemma":[0.000668858,0.00039857137,0.000059718997,0.000024332461,0.000010671219,0.000021534961,0.00035020796,0.0029320698,0.99422985,0.00086738204,0.00025346575,0.00018333666],"about_ca_topic_score_codex":0.000010122678,"about_ca_topic_score_gemma":0.0000014012023,"teacher_disagreement_score":0.05427694,"about_ca_system_score_codex":0.000012534719,"about_ca_system_score_gemma":0.000075264645,"threshold_uncertainty_score":0.6275086},"labels":[],"label_agreement":null},{"id":"W2939227339","doi":"10.1681/asn.2019020143","title":"GNAS: A New Nephrogenic Cause of Inappropriate Antidiuresis","year":2019,"lang":"en","type":"letter","venue":"Journal of the American Society of Nephrology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Nephrogenic diabetes insipidus; Arginine vasopressin receptor 2; Internal medicine; Copeptin; Endocrinology; Medicine; Vasopressin; Tolvaptan; GNAS complex locus; Urinary system; Hyponatremia; Hypocalciuria; Receptor; Hypomagnesemia; Chemistry; Antagonist; Biology; Genetics","score_opus":0.014654018548162413,"score_gpt":0.24834386855736912,"score_spread":0.2336898500092067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939227339","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8601439,0.0023460847,0.0014978723,0.13506928,0.0005880328,0.0002657381,0.000044053326,0.0000036088243,0.00004140285],"genre_scores_gemma":[0.080121346,0.006647299,0.014417757,0.8870597,0.008941669,0.0000030989158,0.00004226823,0.00017428174,0.0025925993],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978751,0.000290123,0.0008164019,0.0002651278,0.0004027627,0.00035046568],"domain_scores_gemma":[0.9952362,0.00007430593,0.0037017819,0.0006321857,0.00030370234,0.00005178062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039822338,0.00030173225,0.0010695645,0.00006020116,0.000040967458,0.000009085616,0.0010059375,0.0005739941,0.000057028123],"category_scores_gemma":[0.000048719543,0.00021392092,0.0017020332,0.00020774697,0.0005176935,0.0000051886755,0.00027313703,0.00097073184,0.0000021327462],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009263954,0.000017146933,0.000075260614,0.000044586828,0.00090189715,0.0000028698737,0.00007105259,0.0000343896,0.49012777,0.0000012340497,0.5083524,0.0002787369],"study_design_scores_gemma":[0.0008165788,0.0017993721,0.000527391,0.0000876157,0.0005112756,0.00026443342,0.00018389453,0.000018704657,0.15571538,0.00017307833,0.83962595,0.00027629556],"about_ca_topic_score_codex":0.00013222561,"about_ca_topic_score_gemma":0.0000029259795,"teacher_disagreement_score":0.78002256,"about_ca_system_score_codex":0.00003061866,"about_ca_system_score_gemma":0.00063828164,"threshold_uncertainty_score":0.8723442},"labels":[],"label_agreement":null},{"id":"W2939452521","doi":"10.1007/978-1-4939-9121-1_11","title":"Combining SRET2 and BiFC to Study GPCR Heteromerization and Protein–Protein Interactions","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Bimolecular fluorescence complementation; G protein-coupled receptor; Förster resonance energy transfer; Protein–protein interaction; Complementation; Receptor; Energy transfer; Chemistry; Fluorescence; Biophysics; Computational biology; Biology; Cell biology; Biochemistry; Physics; Gene","score_opus":0.015304067866769112,"score_gpt":0.36355227770483234,"score_spread":0.3482482098380632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939452521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6096457,0.00013995169,0.3893809,0.000045126268,0.0000835851,0.0006193551,0.0000016659529,0.000006400052,0.000077264725],"genre_scores_gemma":[0.76797825,0.0000066101,0.23158851,0.00014863745,0.000019518839,0.00011542326,0.000015864913,0.00001983553,0.00010735948],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99826056,0.0007285377,0.00023984023,0.00051123754,0.000047088834,0.00021273627],"domain_scores_gemma":[0.9995557,0.000020720177,0.000067349276,0.00025015805,0.000036025467,0.00007001237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006972805,0.00016338135,0.00023080154,0.00012777145,0.00004901027,0.000026543099,0.00010400761,0.00012957826,0.000038026246],"category_scores_gemma":[0.000158886,0.00015773212,0.000032149725,0.0001337007,0.00003437578,0.000004190733,0.00022144901,0.00012946832,0.0000029110124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046731533,0.00005273284,0.0036420538,0.000009018534,0.000033269327,0.000002421777,0.00015155971,0.000023093937,0.983593,0.00057131547,5.5839985e-7,0.011874277],"study_design_scores_gemma":[0.0006828295,0.0013413882,0.000653728,0.000024512825,0.000009099427,0.000010742734,0.0002636165,0.00018056527,0.9939173,0.0014824368,0.0012131284,0.000220652],"about_ca_topic_score_codex":0.000030117606,"about_ca_topic_score_gemma":0.000007930646,"teacher_disagreement_score":0.1583325,"about_ca_system_score_codex":0.000008842077,"about_ca_system_score_gemma":0.0000132058085,"threshold_uncertainty_score":0.6432129},"labels":[],"label_agreement":null},{"id":"W2939655792","doi":"10.1007/978-1-4939-9121-1_22","title":"Laser Doppler Flowmetry to Study the Regulation of Cerebral Blood Flow by G Protein-Coupled Receptors in Rodents","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"","keywords":"Laser Doppler velocimetry; Cerebral blood flow; Blood flow; Receptor; Internal medicine; Cardiology; Medicine; Neuroscience; Biology","score_opus":0.01064090254464618,"score_gpt":0.31917032534831685,"score_spread":0.3085294228036707,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939655792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.827752,0.000202942,0.17053752,0.00005013742,0.00024183276,0.0011517331,0.000006086448,0.000005226986,0.0000525647],"genre_scores_gemma":[0.7653773,0.000006326952,0.23401287,0.00015213511,0.000034541998,0.00013154325,0.00005803215,0.00003073569,0.00019651816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971256,0.001362523,0.00047709316,0.00057651906,0.00013084253,0.0003274135],"domain_scores_gemma":[0.9991728,0.000038869806,0.00012566107,0.00055043306,0.0000616464,0.000050565424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001904629,0.00021526158,0.00034477803,0.00013924397,0.000027946255,0.000011084378,0.0003791412,0.0002729536,0.00023081225],"category_scores_gemma":[0.00022257585,0.000168855,0.00009725352,0.00036802544,0.00003818482,0.0000035453672,0.00021473879,0.00018401536,0.000006079067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008938776,0.00021899916,0.012809962,0.00000684828,0.000070970396,0.0000011196952,0.00012373085,0.00067739614,0.9814469,0.000046763897,0.000020840911,0.0044870772],"study_design_scores_gemma":[0.0013045073,0.0007961385,0.0011313068,0.000014126169,0.000017445924,0.000002533777,0.0001797528,0.0009138852,0.99463373,0.00043335406,0.0003700651,0.00020314181],"about_ca_topic_score_codex":0.00010405206,"about_ca_topic_score_gemma":0.000036585836,"teacher_disagreement_score":0.063475356,"about_ca_system_score_codex":0.000017932005,"about_ca_system_score_gemma":0.000031836218,"threshold_uncertainty_score":0.6885707},"labels":[],"label_agreement":null},{"id":"W2939681462","doi":"10.1007/978-1-4939-9121-1_17","title":"Combining RNAi and Immunofluorescence Approaches to Investigate Post-endocytic Sorting of GPCRs into Multivesicular Bodies","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Endosome; Internalization; Endocytic cycle; G protein-coupled receptor; Cell biology; Receptor; ESCRT; Endocytosis; Chemistry; Clathrin; Protein targeting; Biology; Signal transduction; Membrane protein; Membrane; Biochemistry","score_opus":0.040036670791476645,"score_gpt":0.3315893755796345,"score_spread":0.29155270478815787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939681462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73933524,0.0017100909,0.25832832,0.00008100336,0.000120214536,0.0003097466,0.0000023549994,0.0000075608964,0.00010545332],"genre_scores_gemma":[0.5344418,0.00004093147,0.4652224,0.0002002102,0.000012557683,0.00002519424,0.000017874385,0.000020087753,0.000018960634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977903,0.0007417796,0.0004493661,0.00059029734,0.00007757042,0.00035073343],"domain_scores_gemma":[0.99922234,0.00007875205,0.00017050553,0.00037067296,0.00006775038,0.00008996621],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012196992,0.00023633194,0.00042634326,0.00015517154,0.00004621911,0.000015179407,0.00026427142,0.00022437362,0.000009326305],"category_scores_gemma":[0.00066815113,0.00022249664,0.000097511744,0.00013119572,0.00017105592,0.0000052026703,0.000381201,0.00017295845,0.0000024066471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060472805,0.000023512657,0.0058029345,0.0000578991,0.00005664411,0.000003431148,0.00059400214,0.00030704457,0.9827099,0.003598092,6.1519415e-7,0.006785475],"study_design_scores_gemma":[0.0005114292,0.0005499445,0.0004100091,0.000063494044,0.000013991188,0.000010938933,0.0005825018,0.0007839808,0.993509,0.0031346034,0.00016918303,0.00026095676],"about_ca_topic_score_codex":0.000098391116,"about_ca_topic_score_gemma":0.0000072821836,"teacher_disagreement_score":0.20689407,"about_ca_system_score_codex":0.00001719637,"about_ca_system_score_gemma":0.000053801956,"threshold_uncertainty_score":0.907315},"labels":[],"label_agreement":null},{"id":"W2939733308","doi":"10.1007/978-1-4939-9121-1_18","title":"Super-Resolution Imaging of G Protein-Coupled Receptors Using Ground State Depletion Microscopy","year":2019,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Western University","funders":"","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Cell biology; G protein; Endocytosis; G protein-coupled receptor kinase; Clathrin; Arrestin; Biology; Receptor; Signal transduction; Integral membrane protein; Chemistry; Membrane protein; Biochemistry; Membrane","score_opus":0.014042636468753792,"score_gpt":0.34621347172714384,"score_spread":0.33217083525839003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2939733308","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5204816,0.0006818341,0.47826988,0.000011712993,0.0002465318,0.00027245947,0.000003320157,0.000005754922,0.000026907199],"genre_scores_gemma":[0.4169538,0.000038943323,0.5827184,0.0000734327,0.000034154826,0.00001980453,0.00006515654,0.000034790814,0.000061544735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977176,0.00082477037,0.00044968154,0.00053555885,0.00008602543,0.0003863276],"domain_scores_gemma":[0.9992617,0.000027216156,0.00018881838,0.00037226037,0.00010120765,0.00004882655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001314734,0.00021681872,0.00033317824,0.00015847721,0.00003881338,0.000013451445,0.00021181541,0.0002173361,0.0000924569],"category_scores_gemma":[0.00016642618,0.0002183211,0.00013538178,0.0001955434,0.0001052253,0.0000062588256,0.00014037649,0.00015217325,0.0000034801926],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009807921,0.00003461327,0.004001718,0.000031007403,0.000027747896,0.0000018060367,0.00004385354,0.0004448834,0.9928381,0.00026660805,0.000001626271,0.0022099453],"study_design_scores_gemma":[0.0005903042,0.00022565677,0.00010839962,0.000040317533,0.000010931473,0.000010324492,0.00007189234,0.004416435,0.9919084,0.001572457,0.000804636,0.0002402636],"about_ca_topic_score_codex":0.00023659074,"about_ca_topic_score_gemma":0.0000085894735,"teacher_disagreement_score":0.10444849,"about_ca_system_score_codex":0.000046748148,"about_ca_system_score_gemma":0.000072998875,"threshold_uncertainty_score":0.89028764},"labels":[],"label_agreement":null},{"id":"W2942844979","doi":"10.1021/acs.jmedchem.9b00349","title":"Hybridization of β-Adrenergic Agonists and Antagonists Confers G Protein Bias","year":2019,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs; Deutsche Forschungsgemeinschaft","keywords":"Chemistry; Agonist; Partial agonist; Antagonist; Isoprenaline; Stereochemistry; Ligand (biochemistry); G protein-coupled receptor; Intrinsic activity; Receptor; Arrestin; Biochemistry; Internal medicine; Stimulation","score_opus":0.007380042904262532,"score_gpt":0.2186480947568474,"score_spread":0.21126805185258488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2942844979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972207,0.0012394723,0.0005871291,0.00008727598,0.00011667382,0.00006725466,0.0000034604643,0.000001709963,0.00067631283],"genre_scores_gemma":[0.9984773,0.00022310563,0.00052764436,0.0000397898,0.00028572802,8.9075814e-7,0.000015225171,0.000011970592,0.00041839518],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999092,0.000024816904,0.0003737762,0.00013213708,0.00025855686,0.00011872367],"domain_scores_gemma":[0.9991234,0.000009819082,0.00043900186,0.00012342341,0.00020180485,0.00010257732],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038207512,0.00011081777,0.00023759206,0.000025004903,0.000022114597,0.000011129664,0.00012245988,0.0001112758,0.00015761785],"category_scores_gemma":[0.00010144808,0.0000908769,0.00007738066,0.000045701796,0.00006349034,0.000005384517,0.000032709155,0.00012645597,6.800722e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015250887,0.000026139409,0.0011526037,0.00015382707,0.000045106677,0.000009596639,0.000027504731,0.00003270409,0.9975374,0.000023121593,0.000131268,0.000708271],"study_design_scores_gemma":[0.0009024303,0.00037564884,0.00014507868,0.00018861027,0.000025538227,0.00027172826,0.00018830303,0.00004253112,0.99523485,0.00006149927,0.0024713352,0.000092477094],"about_ca_topic_score_codex":0.0000036581168,"about_ca_topic_score_gemma":2.2295288e-7,"teacher_disagreement_score":0.0023400674,"about_ca_system_score_codex":0.000011928313,"about_ca_system_score_gemma":0.00015470207,"threshold_uncertainty_score":0.37058523},"labels":[],"label_agreement":null},{"id":"W2943839899","doi":"10.3390/md17050286","title":"TAT-Modified ω-Conotoxin MVIIA for Crossing the Blood-Brain Barrier","year":2019,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health; University of British Columbia","funders":"","keywords":"Nasal administration; Pharmacology; Chemistry; Medicine; Blood–brain barrier; Opioid; Central nervous system; Internal medicine; Receptor","score_opus":0.005928948164367856,"score_gpt":0.2336024119408688,"score_spread":0.22767346377650094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943839899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928537,0.00012693675,0.0020239523,0.00042224175,0.00032910853,0.00043523964,0.00001617508,0.00001459586,0.0037780548],"genre_scores_gemma":[0.97761405,0.000008609391,0.0009953646,0.001179865,0.00032685243,0.00005766187,0.00011231092,0.00003367012,0.019671598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911726,0.000037589358,0.00017286639,0.00030946077,0.00009128512,0.00027156863],"domain_scores_gemma":[0.99943113,0.000043677534,0.000066500084,0.0003579142,0.000046931822,0.000053859516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040136895,0.00014437594,0.00013491855,0.00001954835,0.00018797981,0.00011983726,0.00022445974,0.00010743578,0.00031937676],"category_scores_gemma":[0.00006561381,0.0001067306,0.00013870113,0.000044364515,0.00005004683,0.0000036611457,0.00017563275,0.00007970162,0.000019585279],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007189015,0.000019897745,0.00045560917,0.000019330508,0.00005037628,4.6587544e-7,0.00015734494,0.00008052383,0.9887754,0.0015231135,0.0011675223,0.0076785306],"study_design_scores_gemma":[0.0011064736,0.00015936287,0.00016693948,0.000007635654,0.00002166704,0.0000045823886,0.00013998432,0.0005900375,0.78652245,0.0010292975,0.2100414,0.00021014147],"about_ca_topic_score_codex":0.000035715155,"about_ca_topic_score_gemma":0.000011123976,"teacher_disagreement_score":0.20887388,"about_ca_system_score_codex":0.000006390511,"about_ca_system_score_gemma":0.00006009551,"threshold_uncertainty_score":0.43523476},"labels":[],"label_agreement":null},{"id":"W2943853064","doi":"10.1210/js.2019-sat-034","title":"SAT-034 Photometry Based Measurement of G Protein-Coupled Receptor-Mediated Signalling","year":2019,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"G protein-coupled receptor; Biology; Signal transduction; Receptor; Cell biology; Effector; Heterotrimeric G protein; Cell signaling; Context (archaeology); G protein; Genetics","score_opus":0.009870904225782304,"score_gpt":0.2207219590831837,"score_spread":0.2108510548574014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943853064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99498564,0.00079175434,0.0031525427,0.00023655116,0.0004709574,0.00028746578,0.0000069762505,0.0000039609245,0.00006416449],"genre_scores_gemma":[0.99553066,0.00007447396,0.0036863296,0.00019985322,0.000283381,0.000003916536,0.00000601399,0.00002374825,0.00019160277],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998406,0.00009040285,0.0004891326,0.00015323787,0.00064090645,0.0002203511],"domain_scores_gemma":[0.99852955,0.000021838176,0.0006200523,0.0002474363,0.00051039987,0.00007074413],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094568677,0.00015327649,0.00027639666,0.000030429972,0.000056409528,0.000015274258,0.00037608156,0.00008147595,0.00030928035],"category_scores_gemma":[0.00016882524,0.00010286993,0.00068011764,0.00017512061,0.00003489029,0.0000065548447,0.00008100437,0.00024730462,0.000004975671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093717455,0.00007358679,0.00087586854,0.000057034074,0.00018839023,5.131674e-7,0.00003076966,0.00095144304,0.996768,0.000004879922,0.00086258445,0.000093195216],"study_design_scores_gemma":[0.0013450792,0.00035185888,0.00012833523,0.00013847189,0.00003076834,0.000008104354,0.0001721254,0.000895315,0.99100053,0.000020448433,0.0057879123,0.000121054065],"about_ca_topic_score_codex":0.0000068578192,"about_ca_topic_score_gemma":7.9924945e-7,"teacher_disagreement_score":0.0057674902,"about_ca_system_score_codex":0.00005693579,"about_ca_system_score_gemma":0.00021972063,"threshold_uncertainty_score":0.4194914},"labels":[],"label_agreement":null},{"id":"W2943976439","doi":"10.1002/mds.27630","title":"Tardive dyskinesia is associated with altered putamen Akt/GSK‐3β signaling in nonhuman primates","year":2019,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Tardive dyskinesia; Haloperidol; Dyskinesia; Antipsychotic; Pharmacology; Medicine; Dopamine receptor; Dopamine receptor D2; Putamen; Dopaminergic; Typical antipsychotic; Internal medicine; Endocrinology; Dopamine; Atypical antipsychotic; Schizophrenia (object-oriented programming); Psychiatry; Parkinson's disease","score_opus":0.003963383478403596,"score_gpt":0.2001589713908651,"score_spread":0.1961955879124615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943976439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99705493,0.00018492201,0.00067702046,0.00021859595,0.00011140013,0.0004728475,0.000016569067,0.000017905524,0.0012458332],"genre_scores_gemma":[0.99682814,0.000050359296,0.0002600917,0.0016466907,0.000041294177,0.00004218949,0.00021739246,0.00003926914,0.0008745653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867916,0.00004594807,0.00024204883,0.0004390029,0.00022273396,0.00037111682],"domain_scores_gemma":[0.9995264,0.000010892155,0.00012354647,0.00023934408,0.000046186044,0.000053644002],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020147586,0.00022320414,0.00022564315,0.000066448796,0.00006001834,0.00004505195,0.00017982676,0.00011765026,0.00057186245],"category_scores_gemma":[0.000013348267,0.00019926189,0.00007986467,0.000118872835,0.000025566116,0.000009012039,0.000077781726,0.000093139526,0.00001748703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009931491,0.00017050847,0.059230562,0.00002863069,0.0001768905,0.0000023125597,0.00036790964,0.0016642624,0.9367268,0.00008819098,0.0008441324,0.0006004705],"study_design_scores_gemma":[0.0053981626,0.0017122882,0.010703698,0.00020826935,0.000059361166,3.4218274e-7,0.0018668957,0.0014034394,0.97140765,0.00391505,0.0022004836,0.0011243635],"about_ca_topic_score_codex":0.00012453135,"about_ca_topic_score_gemma":0.00016499982,"teacher_disagreement_score":0.048526864,"about_ca_system_score_codex":0.000049099184,"about_ca_system_score_gemma":0.00003836627,"threshold_uncertainty_score":0.81256646},"labels":[],"label_agreement":null},{"id":"W2943981373","doi":"10.1210/js.2019-sat-031","title":"SAT-031 Understanding Gβγ Isoform Interactome Profiles in Fibrotic Gene Regulation","year":2019,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Interactome; Heterotrimeric G protein; Gene isoform; HEK 293 cells; Cell biology; Biology; Transcription (linguistics); Transcription factor; Promoter; Cardiac fibrosis; Gene; Gene expression; Molecular biology; Signal transduction; Genetics; G protein; Fibrosis; Medicine","score_opus":0.0122165747908207,"score_gpt":0.23554921353810257,"score_spread":0.22333263874728188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943981373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99614024,0.00024052258,0.0023742414,0.0004064325,0.0005323566,0.00012939946,0.0000021222872,0.000002161268,0.00017252834],"genre_scores_gemma":[0.99721444,0.00008362677,0.001580993,0.00013821815,0.0002714182,0.0000010191089,0.0000057469415,0.000012942233,0.0006915745],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992466,0.00003996234,0.00028285309,0.00010253264,0.00016704248,0.00016102823],"domain_scores_gemma":[0.99950314,0.000015909436,0.00024818652,0.00014986229,0.000051514355,0.00003141921],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000258967,0.00009189263,0.0001392353,0.000023200004,0.00004544142,0.000024026132,0.0001839515,0.000050489853,0.00010917734],"category_scores_gemma":[0.00003233681,0.00006188034,0.00028150727,0.000085135885,0.000018547446,0.000013324016,0.00008392286,0.00017665478,0.0000031433024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039601684,0.000020999441,0.006017633,0.000021760128,0.00005148127,9.334029e-7,0.00017611963,0.0008941879,0.99110734,0.00014356818,0.0014103706,0.00011599275],"study_design_scores_gemma":[0.001246724,0.00028750798,0.005819638,0.00014796604,0.00002302106,0.00015076733,0.0015087306,0.00095311744,0.9844602,0.0020084812,0.0032292474,0.0001646028],"about_ca_topic_score_codex":0.0000035521145,"about_ca_topic_score_gemma":0.0000022601562,"teacher_disagreement_score":0.006647156,"about_ca_system_score_codex":0.000105373845,"about_ca_system_score_gemma":0.000053630803,"threshold_uncertainty_score":0.2523407},"labels":[],"label_agreement":null},{"id":"W2944055256","doi":"10.1016/j.jsbmb.2019.105376","title":"Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1","year":2019,"lang":"en","type":"article","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Progesterone receptor; Biology; Cell biology; HEK 293 cells; Glycolysis; Biochemistry; Receptor; Metabolism; Estrogen receptor","score_opus":0.0065857650644305125,"score_gpt":0.2252333458945342,"score_spread":0.2186475808301037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944055256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99775684,0.000767306,0.00061108667,0.0003135828,0.000039241226,0.00046540453,0.000032367552,0.0000024084195,0.000011739036],"genre_scores_gemma":[0.9991665,0.00008997279,0.00047571905,0.00008343749,0.000023817047,0.000010858361,0.00009667894,0.000014707985,0.000038295984],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887466,0.00022010901,0.00038491745,0.00021193452,0.0001369569,0.00017142472],"domain_scores_gemma":[0.9991649,0.000042600812,0.00039590124,0.00017188117,0.00016023025,0.00006448762],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055688404,0.00018237092,0.00030052892,0.000051595875,0.000042423108,0.000012651062,0.00015001578,0.00020934876,0.000011737669],"category_scores_gemma":[0.000029252235,0.00012291103,0.000050577768,0.00007389437,0.00012046594,0.000010033813,0.000047233287,0.00018123207,3.233726e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006558411,0.00008882728,0.0023388977,0.00006993934,0.00013118071,0.0000013157995,0.0001039313,0.000021560096,0.99610525,0.000010970268,0.00000321158,0.00046905648],"study_design_scores_gemma":[0.0015282222,0.0018876293,0.00090801355,0.00013255078,0.000052204734,0.00006376715,0.00009122818,0.0000430328,0.9951163,0.000018516366,0.000021502143,0.0001370585],"about_ca_topic_score_codex":0.0000079756255,"about_ca_topic_score_gemma":0.0000021250057,"teacher_disagreement_score":0.0017988019,"about_ca_system_score_codex":0.000011865982,"about_ca_system_score_gemma":0.00006967355,"threshold_uncertainty_score":0.50121665},"labels":[],"label_agreement":null},{"id":"W2944411542","doi":"10.1016/j.pharmthera.2019.05.006","title":"Biased signaling of G protein coupled receptors (GPCRs): Molecular determinants of GPCR/transducer selectivity and therapeutic potential","year":2019,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":151,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Bushehr University of Medical Sciences","keywords":"G protein-coupled receptor; Functional selectivity; Signal transduction; Receptor; Biology; Cell biology; G protein; Computational biology; Chemistry; Biochemistry","score_opus":0.04506476697623272,"score_gpt":0.3434759537930001,"score_spread":0.29841118681676737,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944411542","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15385482,0.84275323,0.0012350548,0.00000813512,0.0005306847,0.001542561,0.00005313329,0.000013931633,0.000008451271],"genre_scores_gemma":[0.15572506,0.8431786,0.00041201367,0.0001601979,0.00014875479,0.00010696701,0.00006899221,0.00013505084,0.00006436904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969213,0.0006727915,0.00093070045,0.00072500424,0.00026754235,0.00048265222],"domain_scores_gemma":[0.9983388,0.00007462233,0.00089928595,0.0003750217,0.00021509096,0.00009718996],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005857797,0.00063494523,0.0017789291,0.0001846752,0.0000738662,0.000015293224,0.00044174746,0.00081060233,0.00017204443],"category_scores_gemma":[0.0000061359733,0.0005656221,0.000591382,0.00023784806,0.00023678926,0.0000059077875,0.000119602315,0.00041808945,0.0000033919475],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014220657,0.00015771545,0.000010044182,0.0035749518,0.0014277038,0.00000506598,0.000045937093,0.000035868354,0.82702076,0.0000047526737,0.000004094736,0.16757087],"study_design_scores_gemma":[0.0011281326,0.00089855364,0.000001020823,0.00095867127,0.004815252,0.000035081986,0.000021437545,0.0004398678,0.881141,0.00003522138,0.109884664,0.00064109406],"about_ca_topic_score_codex":0.000012557915,"about_ca_topic_score_gemma":0.0000015985056,"teacher_disagreement_score":0.16692978,"about_ca_system_score_codex":0.000031231673,"about_ca_system_score_gemma":0.00042832218,"threshold_uncertainty_score":0.9996795},"labels":[],"label_agreement":null},{"id":"W2944698104","doi":"10.1016/j.cmet.2020.02.012","title":"Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits","year":2020,"lang":"en","type":"article","venue":"Cell Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"European Regional Development Fund; Campus France; Université de Bordeaux; Fondation de France; Fondation pour la Recherche Médicale; Conseil régional de Bourgogne-Franche-Comté; Brain and Behavior Research Foundation; Conseil Régional Aquitaine; Agence Nationale de la Recherche; Institut National de la Recherche Agronomique; Institut National de la Santé et de la Recherche Médicale; National Alliance for Research on Schizophrenia and Depression","keywords":"Polyunsaturated fatty acid; Nucleus accumbens; Dopamine; Neuroscience; Dopamine receptor D2; Medium spiny neuron; Mechanism (biology); Biology; Psychology; Striatum; Fatty acid; Biochemistry","score_opus":0.018951438382307218,"score_gpt":0.22072680632003758,"score_spread":0.20177536793773035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944698104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9765925,0.006963366,0.015421833,0.00032925303,0.00015323967,0.00013532404,0.000020608493,0.000024671943,0.00035921167],"genre_scores_gemma":[0.99626315,0.00031261024,0.0019979507,0.00037281695,0.0008408317,0.0000046261866,0.00013161122,0.000024163557,0.000052248444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99904794,0.000054107048,0.00019328365,0.00036571262,0.00011888757,0.0002200713],"domain_scores_gemma":[0.9995581,0.0000098202245,0.00007984647,0.00013810085,0.000065630615,0.00014852316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000098080665,0.00016393902,0.00018269845,0.000026070298,0.00009816898,0.000042847158,0.00011890231,0.00017165151,0.000036822115],"category_scores_gemma":[0.00008199612,0.00014959283,0.000053089367,0.00012920976,0.000033700806,0.000006597477,0.000078694604,0.00011953238,0.000013481314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014222481,0.000005730078,0.00078764744,0.00001440037,0.000010084281,8.968311e-7,0.00011579298,0.000013542945,0.9945119,0.00019848274,0.00006704889,0.004260244],"study_design_scores_gemma":[0.00037614172,0.00008440711,0.006604479,0.000003403667,0.000039012015,0.0000014437436,0.000056647947,0.00008527399,0.98347515,0.00008921637,0.008998646,0.00018619835],"about_ca_topic_score_codex":0.0000074394807,"about_ca_topic_score_gemma":6.283248e-7,"teacher_disagreement_score":0.019670649,"about_ca_system_score_codex":0.000002381583,"about_ca_system_score_gemma":0.00003293739,"threshold_uncertainty_score":0.6100218},"labels":[],"label_agreement":null},{"id":"W2944995184","doi":"10.1096/fj.201900443rr","title":"Stereospecific modulation of dimeric rhodopsin","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; National Institutes of Health; Case Western Reserve University; Alcon Research Institute; Canadian Institute for Advanced Research; Center for Virus Research, University of California, Irvine; University of California, Irvine; Research to Prevent Blindness","keywords":"Rhodopsin; Dimer; Chemistry; Stereochemistry; Stereospecificity; Biophysics; Biochemistry; Biology; Retinal; Organic chemistry","score_opus":0.011539326895501212,"score_gpt":0.22565442251006743,"score_spread":0.2141150956145662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944995184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912028,0.000316682,0.0073665646,0.000037162805,0.0004113116,0.000058296668,0.0000014057964,0.0000016912015,0.00060409034],"genre_scores_gemma":[0.9981725,0.00008181425,0.00055585406,0.00004058563,0.00020308036,5.2166433e-7,0.0000060278903,0.000008638583,0.00093096204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995201,0.00005488672,0.00014452847,0.00007510813,0.000109081266,0.00009629965],"domain_scores_gemma":[0.9996432,0.0000069047887,0.000116861775,0.00015527385,0.000049318507,0.000028450793],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026830452,0.000057077308,0.00007446293,0.000018843863,0.000050445553,0.000017402735,0.00013211394,0.00003891951,0.00039465484],"category_scores_gemma":[0.0000087813105,0.000037012407,0.00007202102,0.000041034324,0.000017275155,0.0000028395484,0.000026985139,0.000079706406,0.000019628373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004488238,0.00000933125,0.0009976429,0.0000024194396,0.000020444191,3.508842e-7,0.00004283383,0.00074562686,0.9948241,0.000085645515,0.0001470109,0.003079726],"study_design_scores_gemma":[0.00026803522,0.00018430779,0.0024878858,0.000012093231,0.000007747891,0.000051730247,0.0001526663,0.0004986495,0.99408275,0.0002972499,0.0018914999,0.00006540171],"about_ca_topic_score_codex":0.0000023176192,"about_ca_topic_score_gemma":3.8699247e-7,"teacher_disagreement_score":0.0069697206,"about_ca_system_score_codex":0.0000053570184,"about_ca_system_score_gemma":0.000021796644,"threshold_uncertainty_score":0.43211937},"labels":[],"label_agreement":null},{"id":"W2947304288","doi":"10.3389/fnins.2019.00581","title":"Activity of the Carboxy-Terminal Peptide Region of the Teneurins and Its Role in Neuronal Function and Behavior in Mammals","year":2019,"lang":"en","type":"review","venue":"Frontiers in Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Hippocampal formation; Biology; Cell biology; Premovement neuronal activity; Glucose uptake; In vivo; Glucose transporter; Extracellular; Neuroprotection; Neuroscience; Transmembrane protein; Central nervous system; Internal medicine; Endocrinology; Insulin; Biochemistry; Receptor; Medicine","score_opus":0.02491515336579862,"score_gpt":0.26053428660114736,"score_spread":0.23561913323534875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947304288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8047332,0.19387512,0.00003216016,0.0000071381023,0.000808423,0.0005174756,0.000011094195,8.264536e-7,0.0000145637905],"genre_scores_gemma":[0.6035796,0.3962201,0.000016847811,0.000020066278,0.000019929697,0.000026557593,9.394984e-7,0.00001211249,0.00010388806],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9988235,0.00021723326,0.00025145506,0.00040555076,0.0001448837,0.00015735965],"domain_scores_gemma":[0.99946314,0.000011236724,0.00024317531,0.0002486597,0.000012201586,0.000021610933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019510886,0.00015265243,0.00037587155,0.000092454284,0.000027672002,0.000009779985,0.00030129057,0.00013764336,3.4308002e-7],"category_scores_gemma":[0.00007073228,0.000099952085,0.000089100766,0.00022482204,0.00013672131,0.000009069558,0.00024647644,0.00022498929,2.1997872e-8],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008925892,0.00027734673,0.089932695,0.0034383805,0.000006261628,0.000013027543,0.00007919974,0.00009325482,0.6747947,0.000051809373,0.000045508157,0.23117858],"study_design_scores_gemma":[0.002084103,0.0018679354,0.8079397,0.008419225,0.0005646159,0.0004376707,0.00015993102,0.00190262,0.09468797,0.00018827694,0.08024264,0.0015053089],"about_ca_topic_score_codex":0.000019500614,"about_ca_topic_score_gemma":0.000020982527,"teacher_disagreement_score":0.718007,"about_ca_system_score_codex":0.000014894372,"about_ca_system_score_gemma":0.00010463257,"threshold_uncertainty_score":0.40759277},"labels":[],"label_agreement":null},{"id":"W2947335069","doi":"10.1101/651463","title":"Genetically encoded intrabody sensors illuminate structural and functional diversity in GPCR-β-arrestin complexes","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Biotechnology and Biological Sciences Research Council","keywords":"G protein-coupled receptor; Arrestin; Receptor; Context (archaeology); Signal transduction; Functional selectivity; Phosphorylation; Biology; Functional diversity; Computational biology; Cell biology; Neuroscience; Biochemistry; Ecology","score_opus":0.014214624836999217,"score_gpt":0.21008299349621318,"score_spread":0.19586836865921395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2947335069","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99589324,0.0007473417,0.0017509342,0.00005678584,0.00089380634,0.0004478519,0.00016066816,0.00004279465,0.0000066030875],"genre_scores_gemma":[0.99595857,0.00018281554,0.0032975401,0.00010642845,0.00036074407,0.000018533674,0.000004395093,0.000060352744,0.0000105990885],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976701,0.00014951684,0.00038223885,0.0010417356,0.00029018897,0.0004661806],"domain_scores_gemma":[0.99872667,0.000026892543,0.00020923687,0.0006003066,0.00023769613,0.00019917336],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003262923,0.0004664422,0.00043937092,0.00014516163,0.00018131411,0.0001035842,0.0003132718,0.0005963154,0.000091743386],"category_scores_gemma":[0.00011572685,0.0005013317,0.00011247242,0.00012724033,0.00014204404,0.000009299746,0.0014401397,0.0004972255,0.000011579009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008250784,0.000027455524,0.03779569,0.000121681005,0.00007715821,0.000016884364,0.000010534028,0.0011860547,0.9603238,0.00029769778,0.00005827404,0.0000022544866],"study_design_scores_gemma":[0.0007915331,0.00010915452,0.29410347,0.00012005604,0.000055546967,9.4470195e-8,0.000009113857,0.0019179946,0.7015415,0.000014851823,0.00054102484,0.00079565786],"about_ca_topic_score_codex":0.00007113024,"about_ca_topic_score_gemma":0.000012394598,"teacher_disagreement_score":0.25878233,"about_ca_system_score_codex":0.000058566795,"about_ca_system_score_gemma":0.00022820393,"threshold_uncertainty_score":0.9997438},"labels":[],"label_agreement":null},{"id":"W2949462723","doi":"10.1101/204859","title":"Structural basis for recognition of diverse antidepressants by the human serotonin transporter","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Serotonin transporter; Transporter; Serotonin; Paroxetine; Neurotransmitter transporter; Reuptake inhibitor; Fluvoxamine; Serotonin Plasma Membrane Transport Proteins; Pharmacology; Chemistry; Neurotransmitter; Sertraline; Reuptake; Antidepressant; Biochemistry; Biology; Fluoxetine; Neuroscience; Receptor; Gene","score_opus":0.025400950422376882,"score_gpt":0.2487521683307163,"score_spread":0.22335121790833942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949462723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941689,0.0005530503,0.0018380545,0.000035697718,0.000545664,0.0008929714,0.0019353305,0.000024800505,0.000005575627],"genre_scores_gemma":[0.9978501,0.00015521709,0.0013256202,0.0000560484,0.0003498624,0.00016234464,0.0000149520865,0.00007386092,0.000011971981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983704,0.00006936907,0.0003817443,0.0006647989,0.00019595784,0.00031774127],"domain_scores_gemma":[0.9980023,0.000014384674,0.00054965704,0.0009887624,0.0003533615,0.00009153283],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036503136,0.00035486533,0.0003696039,0.00004776301,0.00033999525,0.00009832222,0.0006386805,0.0004919965,0.00006595504],"category_scores_gemma":[0.000072441406,0.0003031014,0.0002677253,0.000036892274,0.00013078382,0.000010795339,0.0001819343,0.00024172963,0.0000018420201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004657446,0.000025409725,0.0023488402,0.00017402001,0.00017103103,0.0000015417785,0.0000070902474,0.000012760452,0.99670243,0.000022146456,0.000475347,0.00001279389],"study_design_scores_gemma":[0.00048109915,0.00008264043,0.00844967,0.0001756362,0.00013894051,1.16318235e-8,0.0000050300096,0.000049622784,0.9888797,0.0000071588474,0.0013438901,0.00038664252],"about_ca_topic_score_codex":0.000073927615,"about_ca_topic_score_gemma":0.000005740645,"teacher_disagreement_score":0.007822787,"about_ca_system_score_codex":0.000018464965,"about_ca_system_score_gemma":0.00011963778,"threshold_uncertainty_score":0.9999421},"labels":[],"label_agreement":null},{"id":"W2949615151","doi":"10.1101/254490","title":"A genetically encoded biosensor reveals location bias of opioid drug action","year":2018,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research; University of California, San Francisco; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Internalization; Endosome; Golgi apparatus; Receptor; Neuroscience; Cell biology; Chemistry; Peptide; Opioid peptide; Neuromodulation; Biology; Opioid; Biochemistry","score_opus":0.021564814585685623,"score_gpt":0.24365032766679698,"score_spread":0.22208551308111135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949615151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9843119,0.0013662816,0.012351968,0.000052451313,0.0011381813,0.00059044315,0.00011214132,0.000066277455,0.000010391143],"genre_scores_gemma":[0.9832099,0.0008948839,0.014603867,0.0001269309,0.0009512937,0.0000747265,0.0000036075928,0.00010967419,0.000025097022],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973587,0.00020665018,0.00070250744,0.0009775866,0.00034504826,0.00040952937],"domain_scores_gemma":[0.9968451,0.000022039203,0.00065842917,0.0012021622,0.0010765515,0.00019566504],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006792921,0.00046603204,0.00048126382,0.00016871242,0.00010434507,0.00008396162,0.00047725526,0.000717061,0.000066802386],"category_scores_gemma":[0.00033492368,0.0004921222,0.00020465316,0.00026025786,0.0001468915,0.000007965779,0.0003838274,0.00029744118,0.000031948653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064945765,0.00008914616,0.0008454801,0.00032926712,0.00012545567,0.000002211165,0.0000068402737,0.00008176577,0.99772125,0.00013780629,0.0005892127,0.0000065862114],"study_design_scores_gemma":[0.00030066495,0.00013959,0.0037333376,0.0002873755,0.00008121065,2.3369278e-8,0.000003956071,0.00020567133,0.9911777,0.000008914891,0.0035513574,0.0005102087],"about_ca_topic_score_codex":0.00003635839,"about_ca_topic_score_gemma":0.0000037325942,"teacher_disagreement_score":0.0065435935,"about_ca_system_score_codex":0.000057575442,"about_ca_system_score_gemma":0.0005477465,"threshold_uncertainty_score":0.99975306},"labels":[],"label_agreement":null},{"id":"W2949831296","doi":"10.1111/adb.12791","title":"DCC‐related developmental effects of abused‐ versus therapeutic‐like amphetamine doses in adolescence","year":2019,"lang":"en","type":"article","venue":"Addiction Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Drug Abuse; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Amphetamine; Nucleus accumbens; Dopamine; Striatum; Prefrontal cortex; Dopamine receptor D2; Psychology; Downregulation and upregulation; Regimen; Dopamine receptor; Neuroscience; Pharmacology; Internal medicine; Medicine; Endocrinology; Chemistry","score_opus":0.005692790980613067,"score_gpt":0.2250594701308387,"score_spread":0.21936667915022565,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949831296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967694,0.0010180731,0.00045599014,0.000012252983,0.0010426629,0.00019742297,0.0000046126306,0.00001204334,0.00048753162],"genre_scores_gemma":[0.99888,0.0003504143,0.0003188154,0.00008692811,0.000036628317,0.000012889419,0.00012001645,0.000012039405,0.00018221888],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99920356,0.00007995174,0.00021670452,0.00026733053,0.000050848408,0.00018162576],"domain_scores_gemma":[0.99968624,0.00003641939,0.0000881384,0.00012575438,0.00003394889,0.000029479308],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010387658,0.0001193924,0.00016164099,0.00006198369,0.000022520742,0.0000032843593,0.00010744207,0.00022369428,0.0002740083],"category_scores_gemma":[0.000023327731,0.00010836856,0.000054816228,0.00010807918,0.00005025761,0.0000037271516,0.00004382811,0.00008140408,0.000034283217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019997728,0.00004819238,0.013428692,0.000012082449,0.00006473002,7.3131304e-7,0.000050924496,0.000017831262,0.97962034,0.00026624164,0.00003576221,0.0062545044],"study_design_scores_gemma":[0.0026343665,0.00097119116,0.013792402,0.000041985986,0.000014592563,0.0000066435346,0.00009772589,0.00007003145,0.9750776,0.000071778544,0.0070372038,0.00018447683],"about_ca_topic_score_codex":0.000021956857,"about_ca_topic_score_gemma":0.00001610129,"teacher_disagreement_score":0.0070014414,"about_ca_system_score_codex":0.000020819642,"about_ca_system_score_gemma":0.000041653584,"threshold_uncertainty_score":0.44191417},"labels":[],"label_agreement":null},{"id":"W2950420105","doi":"10.7554/elife.37275","title":"Persistent coding of outcome-predictive cue features in the rat nucleus accumbens","year":2018,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nucleus accumbens; Outcome (game theory); Coding (social sciences); Psychology; Stimulus (psychology); Predictive coding; Neuroscience; Cognitive psychology; Central nervous system","score_opus":0.019937066802624137,"score_gpt":0.27908627375532075,"score_spread":0.2591492069526966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950420105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99639255,0.00037165073,0.0005723196,0.00015582898,0.00027701925,0.0001162095,0.0000108006925,0.0000047732588,0.002098877],"genre_scores_gemma":[0.99846435,0.000056750523,0.00031305672,0.000650326,0.0003214085,0.000006137939,0.000013178383,0.000009075489,0.00016569352],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993499,0.000054610653,0.0001500406,0.00016002053,0.00014361755,0.00014179933],"domain_scores_gemma":[0.9996352,0.0000128847905,0.000056078312,0.00020024968,0.000068719295,0.000026837095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026189926,0.00008154244,0.00010318495,0.000023069437,0.00005992418,0.000013935871,0.00020167934,0.00008349133,0.000051897423],"category_scores_gemma":[0.000086321365,0.00005676148,0.00008484266,0.00005815956,0.00005905965,0.0000021029166,0.00006271815,0.00007500227,0.00000549779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007620613,0.0000424188,0.004338061,0.000009005157,0.00003743008,0.000002098509,0.0010440184,0.000046093915,0.98866856,0.00043137293,0.0048861206,0.00041863194],"study_design_scores_gemma":[0.00043328444,0.00069761265,0.004057814,0.000023389792,0.000021582699,0.000010976108,0.002629358,0.00016045239,0.97421956,0.0000262303,0.017584987,0.00013476552],"about_ca_topic_score_codex":0.000027688202,"about_ca_topic_score_gemma":0.000039478244,"teacher_disagreement_score":0.014448995,"about_ca_system_score_codex":0.000008134503,"about_ca_system_score_gemma":0.000016900372,"threshold_uncertainty_score":0.2314666},"labels":[],"label_agreement":null},{"id":"W2950778246","doi":"10.82308/2215","title":"Characterization of ß-arrestins trafficking and signaling functions on G protein-coupled receptors","year":2015,"lang":"en","type":"article","venue":"eScholarship@McGill (McGill)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Arrestin; G protein-coupled receptor; Endosome; Cell biology; Endocytic cycle; Biology; Signal transduction; Heterotrimeric G protein; Scaffold protein; G protein; Receptor; Rhodopsin-like receptors; G protein-coupled receptor kinase; Endocytosis; Biochemistry; Agonist; Metabotropic receptor; Intracellular","score_opus":0.01980932214708338,"score_gpt":0.22015022875730356,"score_spread":0.20034090661022017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950778246","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99798375,0.000061333725,0.0000677313,0.000013784029,0.000397408,0.00039644065,0.00010072627,0.000047807076,0.0009309908],"genre_scores_gemma":[0.99827164,0.000031990752,0.0007963606,0.000083344064,0.0000883364,0.000047155863,0.00020264476,0.00006068701,0.00041781235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99828404,0.00015535398,0.0004237119,0.0005326829,0.0002982757,0.00030591624],"domain_scores_gemma":[0.998955,0.000022462698,0.00025212957,0.00029415722,0.00024178938,0.00023445892],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006606708,0.0002700467,0.0002602722,0.00011753181,0.00031641923,0.000026018304,0.000162602,0.00025230582,0.000056923214],"category_scores_gemma":[0.0003899228,0.00027146717,0.000101728416,0.00020085514,0.00005230093,0.000030896143,0.00009319085,0.00023604976,0.000014907221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015058483,0.00008137543,0.00003589111,0.000025470074,0.0000453464,0.000002101615,0.000005649822,0.00023673839,0.98368657,0.0019804926,0.0000010130021,0.013748751],"study_design_scores_gemma":[0.0007282104,0.00062988326,0.00006412835,0.00010524244,0.000030062727,0.000009434229,0.000100096004,0.00015814436,0.9873166,0.00039679688,0.010146582,0.00031483595],"about_ca_topic_score_codex":0.000024675275,"about_ca_topic_score_gemma":0.000015289615,"teacher_disagreement_score":0.013433916,"about_ca_system_score_codex":0.000057765075,"about_ca_system_score_gemma":0.00003589231,"threshold_uncertainty_score":0.9999738},"labels":[],"label_agreement":null},{"id":"W2951202717","doi":"10.1002/chin.200251225","title":"1‐(Bicyclopiperazinyl)ethylindoles and 1‐(Homopiperazinyl)ethylindoles as Highly Selective and Potent 5‐HT<sub>7</sub> Receptor Ligands.","year":2002,"lang":"en","type":"article","venue":"ChemInform","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Cantox Health Sciences International","funders":"","keywords":"Chemistry; 5-HT receptor; Stereochemistry; Combinatorial chemistry; Receptor; Biochemistry; Serotonin","score_opus":0.0069927306851618794,"score_gpt":0.2009004774752193,"score_spread":0.19390774679005743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951202717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9769517,0.0056126737,0.000023458555,0.00026195298,0.00019596143,0.00033865107,0.000025294848,0.000052323223,0.01653797],"genre_scores_gemma":[0.98716533,0.009312279,0.00028692657,0.000572778,0.0004822761,0.000056203473,0.00009714165,0.00005806086,0.0019689784],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981626,0.000004348964,0.00040544584,0.0006492593,0.00024974457,0.00052858476],"domain_scores_gemma":[0.99901974,0.000033836877,0.00015230346,0.00032642458,0.00015905692,0.00030861757],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020756527,0.00043354154,0.00036474856,0.000072248295,0.00026573314,0.00012597465,0.00019327443,0.0004377069,0.000068501955],"category_scores_gemma":[0.00012990521,0.000403249,0.00012474816,0.00013477693,0.00017762552,0.000026485892,0.0002047042,0.00027141484,0.000050141087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006752143,0.000048530568,0.00015472792,0.000048137535,0.000073028845,0.0000036907213,0.00051272544,0.0000013565494,0.85112864,0.00009955316,0.0037268442,0.14413524],"study_design_scores_gemma":[0.0011084588,0.0003904977,0.000281383,0.00006194372,0.00003211246,0.00007692611,0.0003470038,0.000058608675,0.9767324,0.00017186684,0.020212304,0.00052652747],"about_ca_topic_score_codex":0.000013793801,"about_ca_topic_score_gemma":0.000012292319,"teacher_disagreement_score":0.1436087,"about_ca_system_score_codex":0.000036271846,"about_ca_system_score_gemma":0.000047904745,"threshold_uncertainty_score":0.9998419},"labels":[],"label_agreement":null},{"id":"W2951698958","doi":"10.1002/chin.200313228","title":"Practice and Principles of Pharmacodynamic Determination of HISS‐Dependent and HISS‐Independent Insulin Action: Methods to Quantitate Mechanisms of Insulin Resistance","year":2003,"lang":"en","type":"article","venue":"ChemInform","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Hiss; Chemistry; Pharmacodynamics; Action (physics); Insulin; Insulin resistance; Pharmacology; Biophysics; Internal medicine; Pharmacokinetics; Nuclear physics; Physics; Medicine","score_opus":0.02549989038512059,"score_gpt":0.33130185490410863,"score_spread":0.30580196451898806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951698958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8466908,0.004975654,0.12821369,0.00009419166,0.00034560566,0.00077890925,0.00005306654,0.00001458822,0.018833509],"genre_scores_gemma":[0.89848834,0.0011176411,0.09931442,0.000030623843,0.0000125835895,0.000015142352,0.000013640101,0.000014713448,0.000992903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989983,0.000014049731,0.00044742468,0.00022697463,0.00018252348,0.00013076718],"domain_scores_gemma":[0.9990426,0.000054194436,0.00041258868,0.00018788816,0.00022661265,0.000076132055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008236873,0.00013645059,0.00022894524,0.00007003742,0.000032796313,0.00000840752,0.000097235985,0.00012368603,0.000028086653],"category_scores_gemma":[0.00041241606,0.00013523121,0.000044562887,0.00009097768,0.00004362933,0.000021640033,0.00007801647,0.00007054276,3.0709373e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020740261,0.000044791963,0.0000063125485,0.00023251558,0.000033374257,7.170625e-7,0.00027910862,0.000006856201,0.954638,0.0028508923,0.000007919715,0.041692078],"study_design_scores_gemma":[0.0005896644,0.00020095492,0.00004377003,0.00005090591,0.000044617253,0.000016151376,0.0006594636,0.000099013094,0.9918617,0.00034578895,0.0059563047,0.00013164605],"about_ca_topic_score_codex":0.0000127089315,"about_ca_topic_score_gemma":0.000013391992,"teacher_disagreement_score":0.05179755,"about_ca_system_score_codex":0.000022051388,"about_ca_system_score_gemma":0.000063199324,"threshold_uncertainty_score":0.55145687},"labels":[],"label_agreement":null},{"id":"W2952033512","doi":"10.1016/j.devcel.2019.05.026","title":"Multimerization and Retention of the Scavenger Receptor SR-B1 in the Plasma Membrane","year":2019,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital; University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Carlsbergfondet; St Peter’s Trust for Kidney Bladder and Prostate Research","keywords":"Internalization; Scavenger receptor; Biology; Endocytic cycle; Cell biology; Receptor; Endocytosis; Transferrin receptor; Biophysics; LDL receptor; Cell membrane; Cytoskeleton; Membrane; Biochemistry; Lipoprotein; Cholesterol; Cell","score_opus":0.006568787612370914,"score_gpt":0.18552362868362446,"score_spread":0.17895484107125353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952033512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99812603,0.00006632563,0.000042879008,0.000031714022,0.00013583129,0.00019871097,0.0000033244135,0.0000014908749,0.0013937145],"genre_scores_gemma":[0.9979904,0.00007195094,0.0011287112,0.00006286948,0.000015355587,0.000006264822,0.000050176943,0.000006647931,0.00066761026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952704,0.000049592465,0.000121040895,0.0001302032,0.000093831826,0.000078312274],"domain_scores_gemma":[0.99983114,0.000006872351,0.000052971627,0.000083546984,0.00001463593,0.000010825427],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017448381,0.000062466606,0.00005650591,0.00001583049,0.000033217766,0.000008747221,0.000097517455,0.000056935314,0.00009637333],"category_scores_gemma":[0.000008170804,0.00003953754,0.000025271178,0.00006810862,0.000018701367,0.0000032118228,0.00004826149,0.000043075182,0.000008963974],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001764401,0.000016497306,0.0039675734,0.00001690604,0.000004054812,7.2635956e-8,0.00024978424,0.0000118397575,0.994841,0.00001826484,0.000055831315,0.0008005353],"study_design_scores_gemma":[0.0003306337,0.000033807682,0.004472199,0.000014930007,0.0000024879494,0.0000023701136,0.00044783353,0.000085372965,0.990835,0.0000066641214,0.0037059633,0.00006274034],"about_ca_topic_score_codex":0.0000067162764,"about_ca_topic_score_gemma":0.0000050729254,"teacher_disagreement_score":0.004005999,"about_ca_system_score_codex":0.0000070415285,"about_ca_system_score_gemma":0.00002037789,"threshold_uncertainty_score":0.1612294},"labels":[],"label_agreement":null},{"id":"W2952808508","doi":"10.1093/cercor/bhy261","title":"High Sensitivity Mapping of Cortical Dopamine D2 Receptor Expressing Neurons","year":2018,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Neuroscience; Biology; Parvalbumin; Dopamine receptor D2; Context (archaeology); Dopamine","score_opus":0.014550133538489954,"score_gpt":0.23821367865412515,"score_spread":0.2236635451156352,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952808508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809268,0.000059458627,0.017787226,0.000048814323,0.00053690333,0.000102900085,0.000019305642,0.000019733825,0.0004988718],"genre_scores_gemma":[0.994354,0.000010543062,0.0042831176,0.00016233389,0.00073251955,0.00000331288,0.00006597283,0.0000260138,0.00036218582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988453,0.00011247331,0.0002628249,0.000359347,0.00014365432,0.00027643907],"domain_scores_gemma":[0.9993179,0.000021848771,0.00011660998,0.00030427432,0.00013686776,0.00010253909],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020588595,0.0001563952,0.00021014432,0.000037166505,0.00012468037,0.000025833782,0.00010608124,0.0001316516,0.00044259586],"category_scores_gemma":[0.00011621065,0.00014859032,0.0000970003,0.00008950328,0.00016744349,0.0000064299797,0.00013510551,0.00011396627,0.000024264695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051865445,0.00003443089,0.0009916739,0.00001223301,0.000022479815,0.000002815653,0.000032917244,0.000004357616,0.994892,0.0002780634,0.0006141435,0.0030630396],"study_design_scores_gemma":[0.00033277826,0.00036895025,0.0075473837,0.00003374739,0.000013852824,0.000016507911,0.00007848207,0.000370079,0.98687035,0.00005910126,0.004116723,0.00019202431],"about_ca_topic_score_codex":0.00003146138,"about_ca_topic_score_gemma":0.000011800921,"teacher_disagreement_score":0.0135041075,"about_ca_system_score_codex":0.0000090830545,"about_ca_system_score_gemma":0.000043176075,"threshold_uncertainty_score":0.6059337},"labels":[],"label_agreement":null},{"id":"W2952840216","doi":"10.82308/6725","title":"Identification and characterization of novel beta-2 adrenegic receptor interacting partners","year":2012,"lang":"en","type":"article","venue":"eScholarship@McGill (McGill)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Heterotrimeric G protein; Endoplasmic-reticulum-associated protein degradation; Cell biology; Endoplasmic reticulum; Biology; G protein-coupled receptor; Proteasome; Receptor; HEK 293 cells; Signal transduction; G protein; Biochemistry; Unfolded protein response","score_opus":0.024082703654798133,"score_gpt":0.2606350874370443,"score_spread":0.23655238378224613,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952840216","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982145,0.00012198896,0.00008158186,0.0000135037735,0.0004614634,0.0001909725,0.00018021242,0.000021419473,0.0007143827],"genre_scores_gemma":[0.99795365,0.00017973378,0.0009808626,0.00007189557,0.00009951798,0.000026183845,0.00032927387,0.00004323741,0.0003156569],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859816,0.00010151803,0.0004449691,0.00036232214,0.00018499466,0.00030806687],"domain_scores_gemma":[0.9990336,0.000026793392,0.00036088316,0.00027994538,0.00014722704,0.00015155876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006579093,0.00020610452,0.0002063423,0.00008039944,0.00023900626,0.000022576505,0.00015164478,0.0001979143,0.000087427405],"category_scores_gemma":[0.00018801315,0.00021361343,0.00009338414,0.00012849047,0.000039076236,0.000079139245,0.0001263147,0.00015880771,0.000014178085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039682287,0.000097378404,0.00025489109,0.000032559932,0.000044378554,1.266901e-7,0.0000058074766,0.0000047244703,0.97915214,0.0050118384,0.0000011635723,0.015355327],"study_design_scores_gemma":[0.00035666476,0.00007442925,0.0007431119,0.000044056313,0.000033724427,0.000010595972,0.00008068822,0.000034562276,0.9822985,0.00004894836,0.016040416,0.00023431187],"about_ca_topic_score_codex":0.0000113212745,"about_ca_topic_score_gemma":0.0000041271683,"teacher_disagreement_score":0.016039252,"about_ca_system_score_codex":0.000037194877,"about_ca_system_score_gemma":0.0000089669065,"threshold_uncertainty_score":0.8710903},"labels":[],"label_agreement":null},{"id":"W2958521934","doi":"10.1042/cs20190479","title":"PBI-4050 via GPR40 activation improves adenine-induced kidney injury in mice","year":2019,"lang":"en","type":"article","venue":"Clinical Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"National Institutes of Health","keywords":"Kidney; Acute kidney injury; Renal injury; Chemistry; Medicine; Endocrinology; Internal medicine","score_opus":0.01905082889978384,"score_gpt":0.3333131916311488,"score_spread":0.314262362731365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2958521934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99767405,0.000009489922,0.00070218625,0.00023545869,0.0006468509,0.00017430152,0.0000017418303,0.000008622843,0.00054729637],"genre_scores_gemma":[0.99764913,0.00001918883,0.0008317833,0.0009631053,0.00020636267,0.0000062987842,0.000009327447,0.000008081055,0.00030669261],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986055,0.00005264078,0.00033599505,0.00053485745,0.00019656896,0.00027443926],"domain_scores_gemma":[0.9993413,0.000028295884,0.000110218825,0.00026527097,0.000075955744,0.00017896168],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011249931,0.00009958646,0.00014185812,0.000046684032,0.00006014639,0.00003661052,0.00039136386,0.00016625428,0.0000738162],"category_scores_gemma":[0.0007752781,0.000085448126,0.0000695055,0.00027411114,0.000117436364,0.000018756382,0.00016057909,0.0001662091,0.000050195922],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053487205,0.00004254391,0.0024916683,0.0000036377894,0.0000022764116,2.8577387e-7,0.000012429673,0.0000032566202,0.98785466,0.000052127656,0.00016014477,0.0093234535],"study_design_scores_gemma":[0.0003307874,0.00047582595,0.010261997,0.000022015662,0.0000020909692,0.000001037388,0.000021564269,0.00072024314,0.98476356,0.00020160794,0.0030510374,0.00014825808],"about_ca_topic_score_codex":0.000038069822,"about_ca_topic_score_gemma":0.0000024593903,"teacher_disagreement_score":0.009175195,"about_ca_system_score_codex":0.000019324314,"about_ca_system_score_gemma":0.00023532179,"threshold_uncertainty_score":0.34844732},"labels":[],"label_agreement":null},{"id":"W2962240229","doi":"10.1016/bs.vh.2019.06.001","title":"Molecular aspects of delta opioid receptors","year":2019,"lang":"en","type":"article","venue":"Vitamins and hormones","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; University of Ottawa; Université de Montréal; Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Receptor; G protein-coupled receptor; δ-opioid receptor; Opioid receptor; Cell biology; Signal transduction; Opioid; Rhodopsin; Biology; Chemistry; Neuroscience; Biochemistry","score_opus":0.004421422473015328,"score_gpt":0.20696932094400836,"score_spread":0.20254789847099303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2962240229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99410003,0.0023145836,0.0007290172,0.000021297563,0.00015731237,0.000112028414,0.000008168301,0.000006144971,0.002551406],"genre_scores_gemma":[0.99836916,0.00069655466,0.00053900306,0.000054141394,0.000050833336,0.0000041549692,0.000035280977,0.000016099957,0.00023479367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999404,0.000016278576,0.00013417321,0.00021874749,0.000087829765,0.00013894422],"domain_scores_gemma":[0.9996573,0.000006535271,0.000055774864,0.00018620094,0.000042259264,0.00005198122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007886963,0.00010697385,0.00014004344,0.00003691743,0.000027061009,0.000012694886,0.000085021595,0.00009623749,0.00006522231],"category_scores_gemma":[0.0000142412455,0.00009443373,0.00005937991,0.000051930674,0.000029960167,0.0000033994982,0.0000655076,0.000037283684,0.0000065750774],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018328356,0.000020734464,0.0009411134,0.000025232435,0.000026429801,0.0000010341519,0.000042291394,0.000012378812,0.99241114,0.0031537616,0.00010347147,0.003244077],"study_design_scores_gemma":[0.0002930661,0.00045016344,0.0011311951,0.00001595237,0.000011385451,0.0000052956393,0.00014182714,0.000043626445,0.98865324,0.00042220036,0.008687985,0.00014407934],"about_ca_topic_score_codex":0.000021258049,"about_ca_topic_score_gemma":0.0000059025174,"teacher_disagreement_score":0.008584514,"about_ca_system_score_codex":0.0000027073572,"about_ca_system_score_gemma":0.000025920126,"threshold_uncertainty_score":0.38508958},"labels":[],"label_agreement":null},{"id":"W2962917495","doi":"10.1016/j.cellsig.2019.109361","title":"Structural determinants governing β-arrestin2 interaction with PDZ proteins and recruitment to CRFR1","year":2019,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; Alberta Innovates; Health Research","keywords":"PDZ domain; Internalization; Signal transducing adaptor protein; G protein-coupled receptor; Cell biology; Receptor; Signal transduction; Biology; Scaffold protein; Biochemistry","score_opus":0.022418374816643046,"score_gpt":0.2520714571760565,"score_spread":0.22965308235941345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2962917495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9829689,0.00026813286,0.015706727,0.000016277918,0.00019713704,0.00067418,0.0000032356445,0.000014051936,0.00015130248],"genre_scores_gemma":[0.9945233,0.000012682899,0.0047292258,0.00007635801,0.00016327399,0.000042695432,0.000028140723,0.000032146465,0.00039218288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898,0.000038499096,0.00017189338,0.00041454314,0.00015269562,0.00024237804],"domain_scores_gemma":[0.9995604,0.000010298249,0.00009478002,0.000173491,0.000051097984,0.000109893685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015028546,0.00017633544,0.00015282552,0.00003621823,0.0000963592,0.00006837598,0.000103970255,0.00008603467,0.000116411495],"category_scores_gemma":[0.000016980917,0.00014858175,0.000039482675,0.000054886437,0.000013744662,0.000009864379,0.000077827135,0.00010586971,0.0000269355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000120001765,0.000006900095,0.0029200043,0.000029760447,0.000022419636,0.00000757931,0.00012994978,0.0016870502,0.9911329,0.00001401122,0.0000064543347,0.0039229593],"study_design_scores_gemma":[0.00036218454,0.00066496705,0.0002064558,0.00014109777,0.0000150243,0.000020472866,0.0002090717,0.003347437,0.9917967,0.00001777834,0.0029630354,0.0002557747],"about_ca_topic_score_codex":0.000027783302,"about_ca_topic_score_gemma":0.000013447724,"teacher_disagreement_score":0.011554339,"about_ca_system_score_codex":0.000022400973,"about_ca_system_score_gemma":0.000029309522,"threshold_uncertainty_score":0.6058988},"labels":[],"label_agreement":null},{"id":"W2963558305","doi":"10.1016/j.neuropharm.2019.107718","title":"Biased agonism of clinically approved μ-opioid receptor agonists and TRV130 is not controlled by binding and signaling kinetics","year":2019,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"H2020 Marie Skłodowska-Curie Actions; Danmarks Frie Forskningsfond; Canadian Institutes of Health Research; Knud Højgaards Fond; Oticon Fonden; H. Lundbeck A/S; Augustinus Fonden; Lundbeckfonden; Carlsbergfondet; European Commission; Toyota Foundation","keywords":"Pharmacology; Agonist; G protein-coupled receptor; Receptor–ligand kinetics; Buprenorphine; Opioid receptor; Internalization; Receptor; Opioid; Functional selectivity; Chemistry; Medicine; Internal medicine","score_opus":0.009853692199721976,"score_gpt":0.26090675723566326,"score_spread":0.25105306503594127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963558305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973817,0.0005221177,0.00048070113,0.00024673942,0.00062158407,0.0005564985,0.00006356408,0.000014524495,0.00011260085],"genre_scores_gemma":[0.9947096,0.0009965755,0.0014561882,0.0020473907,0.00014918248,0.0000230764,0.000045178174,0.00004481954,0.0005279782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981211,0.00021526599,0.0006245419,0.00058489956,0.00013725717,0.0003169312],"domain_scores_gemma":[0.9990091,0.00021130362,0.00034194827,0.0001922553,0.000097643126,0.00014778602],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003501427,0.00024507582,0.0005448809,0.000063172156,0.00006555779,0.000029354866,0.00016815092,0.00026049928,0.00035122834],"category_scores_gemma":[0.00013994727,0.00023094841,0.00011480148,0.00006635628,0.00013495176,0.000005308063,0.00014510029,0.0001980733,0.0000084559015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014075009,0.00008439653,0.0004549746,0.00005068679,0.00009784076,0.0000026609007,0.000055827106,0.00004501458,0.995908,0.000012121354,0.00077419676,0.001106778],"study_design_scores_gemma":[0.007618773,0.0017243159,0.00002671029,0.00001201213,0.000076379525,0.000010651305,0.00003329384,0.0011569173,0.97756577,0.000007841177,0.011533641,0.00023369238],"about_ca_topic_score_codex":0.000005156703,"about_ca_topic_score_gemma":2.3615758e-7,"teacher_disagreement_score":0.01834223,"about_ca_system_score_codex":0.0000065490735,"about_ca_system_score_gemma":0.00004428181,"threshold_uncertainty_score":0.94178027},"labels":[],"label_agreement":null},{"id":"W2963782063","doi":"10.1113/jp278421","title":"Synapses in the heart: sympathetic neuro‐cardiac interaction modulates myocardial remodelling in healthy and diseased myocardium","year":2019,"lang":"en","type":"letter","venue":"The Journal of Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Ted Rogers Centre for Heart Research; University of Toronto","funders":"","keywords":"Heart failure; Medicine; Sympathetic nervous system; Internal medicine; Autonomic nervous system; Cardiology; Norepinephrine; Heart rate; Contractility; Heart disease; Blood pressure; Dopamine","score_opus":0.011966089299402372,"score_gpt":0.244793053090568,"score_spread":0.23282696379116563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963782063","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9463062,0.0034503667,0.00011566139,0.048508614,0.0012790837,0.00030563943,0.000012632869,0.0000022103911,0.000019589397],"genre_scores_gemma":[0.9170318,0.0023000536,0.000028410992,0.0778686,0.002681472,0.0000057934867,0.00004033975,0.000032185188,0.000011344869],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99734986,0.001428465,0.0004787581,0.00024907582,0.00018233481,0.00031152923],"domain_scores_gemma":[0.9988734,0.00033128393,0.00036138034,0.00034259105,0.000064720414,0.000026586471],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00091753196,0.00024119664,0.00054966233,0.00012118776,0.00005752746,0.000024003411,0.00034637513,0.00036731872,0.0000061084374],"category_scores_gemma":[0.000067891284,0.00014328715,0.00026744697,0.00007817309,0.00008011891,0.000008974422,0.000079303514,0.0012552018,0.0000029629587],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00093088654,0.000049901395,0.0001578984,0.00011128756,0.00016755356,0.000021575388,0.00048803163,0.013301965,0.9409464,0.000008038027,0.043514844,0.00030163547],"study_design_scores_gemma":[0.0097960215,0.019729827,0.02331132,0.0020040185,0.0017470295,0.002203315,0.0037090818,0.013755542,0.07866273,0.0128732165,0.8284265,0.003781432],"about_ca_topic_score_codex":0.000035227993,"about_ca_topic_score_gemma":0.0000019597476,"teacher_disagreement_score":0.86228365,"about_ca_system_score_codex":0.000025953095,"about_ca_system_score_gemma":0.00009157741,"threshold_uncertainty_score":0.584308},"labels":[],"label_agreement":null},{"id":"W2963850864","doi":"10.1016/j.bcp.2019.07.018","title":"Interplay between intracellular loop 1 and helix VIII of the angiotensin II type 2 receptor controls its activation","year":2019,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Angiotensin II; Receptor; Helix (gastropod); G protein-coupled receptor; Transmembrane domain; Angiotensin receptor; Cell biology; Intracellular; Signal transduction; Mutant; Effector; Chemistry; Biology; Biochemistry","score_opus":0.00937786724955265,"score_gpt":0.2709522674717538,"score_spread":0.2615744002222012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963850864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99727476,0.0010728957,0.00018002724,0.00054419064,0.00051110075,0.0003280776,0.000016172158,0.0000075297203,0.000065221524],"genre_scores_gemma":[0.9983883,0.00007883732,0.00015358829,0.00044767393,0.00035410747,0.000006130852,0.00005677981,0.000017165192,0.00049740187],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911886,0.00008050839,0.00022311766,0.00028995136,0.00009204346,0.00019553101],"domain_scores_gemma":[0.9994993,0.000033990324,0.0001284682,0.00015104571,0.00012104719,0.000066100474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015058044,0.00013853912,0.00020993668,0.000025460173,0.000050412364,0.0000059620584,0.00018118643,0.00025437647,0.00043403896],"category_scores_gemma":[0.00005342304,0.00010686633,0.000075997894,0.000087084634,0.00007777783,0.000004492954,0.00022592195,0.00014405485,0.000013236352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018036527,0.000033207063,0.00024604387,0.000015946778,0.00008718015,1.2759425e-7,0.000021474258,0.0000064645883,0.9854089,0.000033956738,0.013761781,0.00020454789],"study_design_scores_gemma":[0.00074078137,0.00029809307,0.00010966804,0.000017167684,0.000038024264,0.0000022479844,0.0000128865095,0.0000917532,0.9766609,0.000018930852,0.021887483,0.000122054524],"about_ca_topic_score_codex":0.0000040322757,"about_ca_topic_score_gemma":5.709091e-8,"teacher_disagreement_score":0.008747996,"about_ca_system_score_codex":0.000014234732,"about_ca_system_score_gemma":0.000040847182,"threshold_uncertainty_score":0.4752422},"labels":[],"label_agreement":null},{"id":"W2964093992","doi":"10.1523/eneuro.0035-19.2019","title":"GPR88 in D1R-Type and D2R-Type Medium Spiny Neurons Differentially Regulates Affective and Motor Behavior","year":2019,"lang":"en","type":"article","venue":"eNeuro","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Walloon excellence in life sciences and biotechnology; National Institute on Drug Abuse; Conseil Régional d'Alsace; Fonds Unique Interministériel; Canada Research Chairs; Canada Foundation for Innovation; Fondation pour la Recherche Médicale; Fonds De La Recherche Scientifique - FNRS","keywords":"Medium spiny neuron; Striatum; Nucleus accumbens; Open field; Neuroscience; Motor coordination; Pharmacology; Psychology; Biology; Endocrinology; Dopamine","score_opus":0.006368443027636973,"score_gpt":0.22493132842401087,"score_spread":0.2185628853963739,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964093992","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99853265,0.00046074393,0.00001749161,0.000046517867,0.00054738333,0.00026469203,0.0000049253995,0.000010408126,0.00011518071],"genre_scores_gemma":[0.9987306,0.0003050519,0.00012118404,0.00011230459,0.000096533935,0.000008302811,0.000022326478,0.00002630937,0.0005773748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915874,0.00006303684,0.00012176627,0.00038227276,0.000084446365,0.00018971563],"domain_scores_gemma":[0.999632,0.000019636816,0.00004123835,0.00019000439,0.00004287269,0.00007422756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006373154,0.00014903411,0.0001542935,0.00004572536,0.00003503181,0.000030649455,0.00008259595,0.00011615524,0.00007021124],"category_scores_gemma":[0.00006216158,0.00013774079,0.000026335905,0.000069822716,0.000035712874,0.000005373615,0.00012234264,0.000102770224,0.000005846162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007586904,0.000032099193,0.0127936145,0.0000120748555,0.000008058411,0.0000074394875,0.00004167591,0.0000048470474,0.98574734,0.000028116528,0.000049087655,0.0011997697],"study_design_scores_gemma":[0.0006594121,0.0011819671,0.27460468,0.000018704632,0.000024281677,0.000023429617,0.00003572449,0.00009289575,0.72150284,0.00007208522,0.0015535236,0.0002304367],"about_ca_topic_score_codex":0.000020156396,"about_ca_topic_score_gemma":0.000019993435,"teacher_disagreement_score":0.2642445,"about_ca_system_score_codex":0.0000046308646,"about_ca_system_score_gemma":0.000027655313,"threshold_uncertainty_score":0.5616907},"labels":[],"label_agreement":null},{"id":"W2964598535","doi":"10.1074/jbc.ac119.009848","title":"Detergent- and phospholipid-based reconstitution systems have differential effects on constitutive activity of G-protein–coupled receptors","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Government of Canada; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Howard Hughes Medical Institute","keywords":"Phospholipid; Chemistry; Receptor; G protein-coupled receptor; Phospholipid transfer protein; Biophysics; Biochemistry; Biology; Membrane","score_opus":0.01113166083985868,"score_gpt":0.22476093919511891,"score_spread":0.21362927835526024,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2964598535","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962788,0.0003621275,0.002463005,0.000013479469,0.0004863376,0.00019371998,0.000010070655,0.000004112348,0.00018835477],"genre_scores_gemma":[0.9993947,0.00008398444,0.00017763476,0.000018651042,0.00024262609,0.0000052473224,0.000012492165,0.0000068327504,0.000057809597],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902695,0.0000780454,0.000332483,0.00024034576,0.00015430067,0.0001678773],"domain_scores_gemma":[0.99908745,0.00005869795,0.00046621318,0.0001459196,0.00012877547,0.000112932896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021370665,0.00018174085,0.00037945004,0.000024159928,0.000040924446,0.00001724214,0.00013025945,0.000326436,0.00011594555],"category_scores_gemma":[0.00018576493,0.00012837793,0.00017437334,0.00003481602,0.00013466139,0.0000054304064,0.000041292424,0.00020385279,0.0000015447798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00080160453,0.00008962323,0.0020239549,0.00012110089,0.00007112973,0.0000041365956,0.000004159014,0.000124774,0.9959064,0.000023007779,0.000013043266,0.0008170785],"study_design_scores_gemma":[0.0011218132,0.001030994,0.00026171218,0.00021928051,0.000020824831,0.000023940438,0.00003128125,0.00029140958,0.99651307,0.000018135772,0.0003168949,0.0001506502],"about_ca_topic_score_codex":0.000005241813,"about_ca_topic_score_gemma":1.7080629e-7,"teacher_disagreement_score":0.0031159292,"about_ca_system_score_codex":0.000030412682,"about_ca_system_score_gemma":0.000083712555,"threshold_uncertainty_score":0.52351004},"labels":[],"label_agreement":null},{"id":"W2967075857","doi":"10.1074/jbc.ra119.010089","title":"Cryo-EM structure of the native rhodopsin dimer in nanodiscs","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Eye Institute; University of California, Irvine; Canada Excellence Research Chairs, Government of Canada; Alcon Research Institute; Canadian Institute for Advanced Research; National Institutes of Health; Case Western Reserve University; University of California; Allergan; Research to Prevent Blindness","keywords":"Rhodopsin; G protein-coupled receptor; Transducin; Transmembrane domain; Dimer; Biophysics; Crystallography; Chemistry; Helix (gastropod); Opsin; Membrane; Cryo-electron microscopy; Biology; Receptor; Biochemistry","score_opus":0.00925135051961739,"score_gpt":0.23153490660373421,"score_spread":0.22228355608411682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2967075857","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987765,0.00055254507,0.00004333857,0.000046859564,0.00016445036,0.000055912824,0.0000119248325,9.671598e-7,0.00034752578],"genre_scores_gemma":[0.99921644,0.000056554032,0.00030813686,0.00007614209,0.0001422388,3.566497e-7,0.000005355318,0.000005940643,0.00018882814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991863,0.000057217858,0.00034175304,0.00013912297,0.00014063665,0.00013498256],"domain_scores_gemma":[0.99933845,0.000022738684,0.00033713135,0.00015388563,0.00010646536,0.00004134086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001832348,0.000112043104,0.00022951276,0.0000118013095,0.000017656588,0.000007445676,0.000312715,0.0002546903,0.0003993158],"category_scores_gemma":[0.00015487161,0.000060019804,0.00017260897,0.00008374263,0.0000569922,0.0000030102099,0.00009953486,0.00024571826,6.661517e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008636012,0.0000328412,0.007972336,0.000017132297,0.000020784331,0.0000014916501,0.00003266001,0.0000877077,0.9914634,0.000012471281,0.000077142286,0.0001956715],"study_design_scores_gemma":[0.00039274077,0.00014188461,0.0034044515,0.000041402902,0.000005634314,0.00003720928,0.00023582176,0.00000547204,0.994462,0.00034939847,0.0008403273,0.00008366502],"about_ca_topic_score_codex":0.0000012935773,"about_ca_topic_score_gemma":8.337098e-7,"teacher_disagreement_score":0.0045678853,"about_ca_system_score_codex":0.000015946043,"about_ca_system_score_gemma":0.00005783696,"threshold_uncertainty_score":0.43722278},"labels":[],"label_agreement":null},{"id":"W2969585325","doi":"10.1101/746693","title":"Molecular Basis for G-protein-Coupled Receptor (GPCR) Activation and Biased Signalling at the Platelet Thrombin Receptor Proteinase Activated Receptor-4 (PAR4)","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Protease-activated receptor; G protein-coupled receptor; Receptor; Arrestin; Thrombin; Biochemistry; G protein-coupled receptor kinase; Cell biology; Chemistry; Functional selectivity; Formyl peptide receptor; Peptide; Protease-activated receptor 2; Biology; 5-HT5A receptor; Chemotaxis; Platelet","score_opus":0.013292419156695035,"score_gpt":0.2160666641753195,"score_spread":0.20277424501862445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2969585325","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96596265,0.0010842705,0.025620045,0.00048766955,0.00086250633,0.0052713784,0.0005506605,0.00015727703,0.0000035516266],"genre_scores_gemma":[0.98442525,0.00040470948,0.011990027,0.00030121472,0.00070935726,0.0016598982,0.00006228866,0.00038178844,0.0000654989],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9951272,0.00038607986,0.00087861874,0.0020790682,0.0005755579,0.0009535031],"domain_scores_gemma":[0.99618524,0.00011560661,0.0010144889,0.0015737067,0.00078001054,0.00033092857],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0012617016,0.0010976335,0.00088369177,0.00020253302,0.00056426076,0.00034879072,0.00077842246,0.0014691454,0.00037200045],"category_scores_gemma":[0.0007746366,0.0009992407,0.00041832682,0.00037370002,0.0001886822,0.000038731192,0.000793859,0.0008019935,0.000043509233],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00070670067,0.00012280289,0.00003873134,0.00045403067,0.0004879013,0.0000022072254,0.000015976624,0.0022273476,0.9951364,0.00009665554,0.0007005335,0.000010735976],"study_design_scores_gemma":[0.0013878897,0.00039870874,0.00004267521,0.00069346384,0.000085158,4.7634536e-8,0.000017233817,0.0015703078,0.9850682,0.0000031696704,0.009491009,0.0012421596],"about_ca_topic_score_codex":0.00006825058,"about_ca_topic_score_gemma":0.0000025262455,"teacher_disagreement_score":0.018462576,"about_ca_system_score_codex":0.00029949346,"about_ca_system_score_gemma":0.00064549065,"threshold_uncertainty_score":0.99982715},"labels":[],"label_agreement":null},{"id":"W2970208187","doi":"10.1093/oxfordhb/9780190649739.013.4","title":"Involvement of the Sex Hormones in Learning and Memory","year":2019,"lang":"en","type":"reference-entry","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Cognition; Memory consolidation; Hormone; Psychology; Neuroscience; Cognitive science; Developmental psychology; Biology; Cognitive psychology; Hippocampus","score_opus":0.01279342808036693,"score_gpt":0.23547627690775058,"score_spread":0.22268284882738365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970208187","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.765967,0.03337141,0.00029787497,0.00007295189,0.0010145797,0.00072312186,0.000023901131,0.00000949505,0.19851962],"genre_scores_gemma":[0.5544477,0.080093354,0.00027980836,0.00011357108,0.0003071557,0.000021019994,0.00020104897,0.000046657427,0.36448964],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992182,0.0000676779,0.0001969976,0.00025256333,0.0001292993,0.00013522402],"domain_scores_gemma":[0.9996412,0.000009913377,0.00011993795,0.00017877558,0.000027871512,0.000022316239],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016827395,0.00014687584,0.00021699067,0.000035486,0.000026403592,0.000010824191,0.00014234138,0.0002863047,0.000098705015],"category_scores_gemma":[0.000019978826,0.00009579046,0.000073545074,0.00003828241,0.00002890742,8.757296e-7,0.00023576716,0.00020622453,0.0000014917143],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009331437,0.00015360783,0.014668936,0.0015523114,0.00036868657,0.0000028123218,0.00061863096,0.00023640334,0.8353241,0.00036994196,0.037008982,0.109602265],"study_design_scores_gemma":[0.0006778472,0.00033429626,0.00025444702,0.0004173093,0.00003933262,0.0000037513855,0.0014735623,0.000077779376,0.6687636,0.000116715346,0.32743204,0.00040936386],"about_ca_topic_score_codex":0.00006701359,"about_ca_topic_score_gemma":0.000042002837,"teacher_disagreement_score":0.29042304,"about_ca_system_score_codex":0.000009207845,"about_ca_system_score_gemma":0.000087656896,"threshold_uncertainty_score":0.39062217},"labels":[],"label_agreement":null},{"id":"W2970852343","doi":"10.1002/cmdc.201900466","title":"Single Amino Acid Replacement in G‐7039 Leads to a 70‐fold Increase in Binding toward GHS‐R1a","year":2019,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lakehead University; Thunder Bay Regional Research Institute; Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chemistry; G protein-coupled receptor; Receptor; Secretagogue; Internal medicine; Stereochemistry; Endocrinology; Molecular biology; Biochemistry; Biology; Medicine","score_opus":0.01701090912255469,"score_gpt":0.24456886450504078,"score_spread":0.2275579553824861,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970852343","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99593675,0.00023298906,0.00017740605,0.0001949695,0.00019728819,0.00036561192,0.0000065387067,0.000015178336,0.0028732882],"genre_scores_gemma":[0.9967733,0.000025439142,0.0010340912,0.00049209653,0.00012649527,0.0000571818,0.000094818686,0.000036686764,0.0013598712],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983782,0.00003775252,0.00034228637,0.000588887,0.00018370882,0.00046912977],"domain_scores_gemma":[0.99931353,0.000012976196,0.00007439169,0.00041089137,0.000035148976,0.00015306791],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004087176,0.00022684004,0.00026794407,0.00013804557,0.00002200514,0.000033179676,0.00024837558,0.00021525228,0.00032823288],"category_scores_gemma":[0.000111920184,0.00023510876,0.00008405415,0.00024154955,0.00001894484,0.0000079090605,0.00021430297,0.00015301019,0.00012334302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001638923,0.000118475364,0.0076247235,0.000040035822,0.0000105881245,0.000008962743,0.00025792167,0.00002375966,0.9900888,0.000030173404,0.00060832634,0.0010243068],"study_design_scores_gemma":[0.0010259371,0.00032471376,0.00026274504,0.000086334665,0.000004814184,0.0000060776433,0.00033600788,0.000056760142,0.9924268,0.00002659576,0.005143191,0.00030000103],"about_ca_topic_score_codex":0.00006580155,"about_ca_topic_score_gemma":0.00005398435,"teacher_disagreement_score":0.0073619783,"about_ca_system_score_codex":0.00012777101,"about_ca_system_score_gemma":0.000059825008,"threshold_uncertainty_score":0.9587457},"labels":[],"label_agreement":null},{"id":"W2971813601","doi":"10.1007/s00232-019-00091-4","title":"Effects of Post-translational Modifications on Membrane Localization and Signaling of Prostanoid GPCR–G Protein Complexes and the Role of Hypoxia","year":2019,"lang":"en","type":"review","venue":"The Journal of Membrane Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Manitoba; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Research Manitoba","keywords":"Prostanoid; G protein-coupled receptor; Human physiology; Hypoxia (environmental); Posttranslational modification; Cell biology; Chemistry; Receptor; Biochemistry; Biology; Endocrinology; Enzyme; Oxygen","score_opus":0.01421083796260811,"score_gpt":0.26096282709470514,"score_spread":0.24675198913209703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2971813601","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.042729925,0.9542624,0.0017083426,0.000041180705,0.00006950086,0.0010875115,0.00006530225,0.0000013394259,0.00003449267],"genre_scores_gemma":[0.3445458,0.6550303,0.0002153676,0.000015781856,0.000088852474,0.000010630265,0.000056114513,0.000021282684,0.000015881062],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99801695,0.0007373004,0.0008266401,0.00014991044,0.00015235921,0.00011681512],"domain_scores_gemma":[0.9976259,0.00046344983,0.0014001015,0.00019784777,0.00028013543,0.000032560387],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010421119,0.00020869073,0.000979308,0.000105713174,0.000057680147,0.000005350662,0.00026832664,0.00025074827,0.000011103474],"category_scores_gemma":[0.00015831053,0.000108782806,0.00021991982,0.00009131134,0.0003548751,0.0000047815693,0.000047305137,0.00018531772,2.326022e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048680467,0.000049035087,0.0000020092825,0.004121759,0.0002970643,1.3713509e-7,0.00012728723,0.0001685236,0.9736206,0.0032079986,0.0000010497014,0.01791771],"study_design_scores_gemma":[0.0015631361,0.0013084213,0.000006308014,0.0030950094,0.0009886741,0.00007957964,0.00009536572,0.00013083429,0.979263,0.00095679035,0.012330387,0.00018249144],"about_ca_topic_score_codex":0.000015204586,"about_ca_topic_score_gemma":0.0000015435734,"teacher_disagreement_score":0.3018159,"about_ca_system_score_codex":0.000005190358,"about_ca_system_score_gemma":0.00014855593,"threshold_uncertainty_score":0.4436034},"labels":[],"label_agreement":null},{"id":"W2972023618","doi":"10.1038/s41380-019-0512-3","title":"ELFN2 is a postsynaptic cell adhesion molecule with essential roles in controlling group III mGluRs in the brain and neuropsychiatric behavior","year":2019,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Eye Institute; National Institute on Drug Abuse; Canadian Institutes of Health Research; U.S. Department of Health and Human Services; National Institutes of Health; National Institute of Mental Health","keywords":"Metabotropic glutamate receptor; Neuroscience; G protein-coupled receptor; Postsynaptic potential; Glutamatergic; Interactome; Biology; Neurotransmission; Psychology; Signal transduction; Glutamate receptor; Receptor; Cell biology; Biochemistry","score_opus":0.0019934609360643956,"score_gpt":0.19830364396256392,"score_spread":0.19631018302649952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972023618","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99338377,0.0030118802,0.001554872,0.00079072156,0.00023666992,0.00078327133,0.000005479206,0.000010700104,0.00022262886],"genre_scores_gemma":[0.99623454,0.000077396915,0.0011039044,0.002305597,0.00007947239,0.0000657052,0.00003739761,0.000053973356,0.000042017746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99811125,0.00022083642,0.00033520526,0.00065817934,0.00026699356,0.00040754612],"domain_scores_gemma":[0.9993009,0.000016571681,0.00012465489,0.00045749487,0.00002848588,0.00007191941],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032059778,0.00029651637,0.0002605184,0.00015614416,0.00006680658,0.00007293792,0.00030494342,0.00017443325,0.000031861084],"category_scores_gemma":[0.000007459922,0.00023207262,0.0001156911,0.000285894,0.00004036104,0.000009969575,0.00007068071,0.0002792979,0.00000723706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031442408,0.0002730608,0.018958926,0.000035897596,0.00001845476,0.000041792777,0.00015818172,0.00014364101,0.97947264,0.0003406702,0.00008687104,0.00015546224],"study_design_scores_gemma":[0.05686842,0.014747331,0.071440905,0.00074032956,0.00075655174,0.00090922514,0.00879621,0.009411521,0.8270091,0.0019182456,0.0020455054,0.0053566704],"about_ca_topic_score_codex":0.00006133587,"about_ca_topic_score_gemma":0.00013213497,"teacher_disagreement_score":0.15246353,"about_ca_system_score_codex":0.000009852814,"about_ca_system_score_gemma":0.000060205624,"threshold_uncertainty_score":0.9463647},"labels":[],"label_agreement":null},{"id":"W2972158106","doi":"10.1038/s41467-019-11875-6","title":"Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"National Institute of General Medical Sciences; Fonds de Recherche du Québec - Santé; Foundation for the National Institutes of Health; Réseau québécois de recherche sur la douleur; Canadian Institutes of Health Research; Mitacs; National Institutes of Health; Government of Canada; Natural Sciences and Engineering Research Council of Canada; Pfizer","keywords":"G protein-coupled receptor; Computational biology; Cluster analysis; Effector; Receptor; Signal transduction; Bioinformatics; Computer science; Medicine; Biology; Pharmacology; Artificial intelligence; Cell biology; Biochemistry","score_opus":0.12695518435309022,"score_gpt":0.35042341801440907,"score_spread":0.22346823366131885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972158106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99767214,0.00039325576,0.0007910004,0.00048083265,0.00021383043,0.0003458773,0.000050716193,0.000011244422,0.0000411019],"genre_scores_gemma":[0.97364116,0.0002041695,0.025629314,0.00026812422,0.00005106144,0.00003508525,0.00004738056,0.000023140128,0.00010055324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987956,0.00022422333,0.00045794115,0.00022201937,0.00014532739,0.00015484431],"domain_scores_gemma":[0.9979346,0.00029680296,0.00014622416,0.0012283628,0.00030181865,0.00009220295],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00097120076,0.00011131608,0.0002457418,0.00009411425,0.00006506486,0.000017744365,0.000644753,0.00023323362,0.00001710924],"category_scores_gemma":[0.0008845954,0.00011097741,0.00012602026,0.00021812718,0.000025549381,0.000012142164,0.00059379736,0.0002936537,0.00000765132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033106367,0.00006686747,0.004402279,0.000012822374,0.000051588282,1.0862902e-7,0.00024888862,0.0006504986,0.9931036,0.000105115105,0.00012105804,0.0009060881],"study_design_scores_gemma":[0.0003182423,0.00042668986,0.0075586163,0.00013741304,0.000019896814,6.697221e-7,0.0002513097,0.00028604665,0.9754713,0.0000073270267,0.015354583,0.0001678901],"about_ca_topic_score_codex":0.000014863617,"about_ca_topic_score_gemma":0.000031587093,"teacher_disagreement_score":0.024838313,"about_ca_system_score_codex":0.000014761441,"about_ca_system_score_gemma":0.000066517525,"threshold_uncertainty_score":0.45255274},"labels":[],"label_agreement":null},{"id":"W2972371513","doi":"10.1007/s00429-019-01957-y","title":"Altered motor, anxiety-related and attentional task performance at baseline associate with multiple gene copies of the vesicular acetylcholine transporter and related protein overexpression in ChAT::Cre+ rats","year":2019,"lang":"en","type":"article","venue":"Brain Structure and Function","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Rosetrees Trust; Northumbria University","keywords":"Vesicular acetylcholine transporter; Cholinergic; Choline acetyltransferase; Cre recombinase; Acetylcholine; Endocrinology; Biology; Internal medicine; Neuroscience; Transgene; Psychology; Genetically modified mouse; Medicine; Gene; Genetics","score_opus":0.002301709692332762,"score_gpt":0.16401059846010918,"score_spread":0.16170888876777642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972371513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9988159,0.0004805225,0.00010958355,0.00007969214,0.00005657563,0.00040676238,0.00003964496,0.000004460533,0.000006838244],"genre_scores_gemma":[0.9990319,0.00010123727,0.00014642629,0.00007125319,0.000033870037,0.000007582151,0.00021951123,0.000012715546,0.00037549456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992685,0.000059137383,0.00018142526,0.00026781054,0.00011012092,0.00011303331],"domain_scores_gemma":[0.99968886,0.0000085334,0.00011933315,0.00011502798,0.000037631195,0.000030624786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014518,0.00013017424,0.00013825473,0.000025295782,0.000077452045,0.000009641886,0.000032766908,0.0001781792,0.000045652036],"category_scores_gemma":[0.000011252941,0.000085723565,0.000029293999,0.000058062193,0.000045241748,0.000014264365,0.00003336972,0.000107137894,1.6855564e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004129627,0.000009288339,0.04105054,0.000050191877,0.00003816854,1.6907308e-7,0.00007966173,0.00016626612,0.95743877,0.00000781328,0.00001737695,0.00072880054],"study_design_scores_gemma":[0.0023196528,0.00029476453,0.22080062,0.00022545204,0.000019200395,0.000018807787,0.00003195673,0.0019042775,0.7736871,0.000060324324,0.00049177365,0.00014605987],"about_ca_topic_score_codex":0.000010704952,"about_ca_topic_score_gemma":0.000011366972,"teacher_disagreement_score":0.18375166,"about_ca_system_score_codex":0.000008083703,"about_ca_system_score_gemma":0.00001284146,"threshold_uncertainty_score":0.34957054},"labels":[],"label_agreement":null},{"id":"W2972893223","doi":"10.1124/pr.119.018044","title":"Beyond the Ligand: Extracellular and Transcellular G Protein–Coupled Receptor Complexes in Physiology and Pharmacology","year":2019,"lang":"en","type":"review","venue":"Pharmacological Reviews","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; National Eye Institute; National Institute of Mental Health; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Extracellular; Transcellular; G protein-coupled receptor; Ligand (biochemistry); Molecular Pharmacology; Receptor; Pharmacology; Cell biology; Chemistry; Biology; Biochemistry","score_opus":0.062849133186057,"score_gpt":0.34547505308126847,"score_spread":0.28262591989521146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972893223","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009326717,0.9850218,0.00008379111,0.00009843847,0.00042725832,0.0049444316,0.000030059053,0.000014316187,0.000053183234],"genre_scores_gemma":[0.0007266358,0.9959887,0.00029450972,0.00049955916,0.0005420183,0.0011642566,0.00020224284,0.000059451828,0.00052257435],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99565697,0.0014199918,0.0010784044,0.0011160006,0.00013859494,0.0005900382],"domain_scores_gemma":[0.9988295,0.00016070706,0.000490381,0.00030515713,0.000036767684,0.00017751382],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001430382,0.0007401534,0.0023595612,0.00008245745,0.00014293526,0.00004235338,0.00052741275,0.0006452823,0.0009119361],"category_scores_gemma":[0.00006807487,0.0004330597,0.00047667476,0.00019155697,0.00029287196,0.000007717159,0.00028738394,0.0008020273,0.00006858708],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004462902,0.000088023815,6.2863444e-7,0.005196783,0.00013722396,0.0000074964455,0.000021491081,9.353992e-7,0.7963386,0.00009265741,0.0008451949,0.19722635],"study_design_scores_gemma":[0.0006604019,0.00032227437,5.2361213e-7,0.0007111149,0.0006772528,0.000033896362,0.0000070623087,0.00004281212,0.018897928,0.00009113787,0.97804487,0.00051072804],"about_ca_topic_score_codex":0.000005026611,"about_ca_topic_score_gemma":0.0000018386867,"teacher_disagreement_score":0.9771997,"about_ca_system_score_codex":0.000028287712,"about_ca_system_score_gemma":0.00009051387,"threshold_uncertainty_score":0.9998121},"labels":[],"label_agreement":null},{"id":"W2972947209","doi":"10.1016/b978-0-12-816228-6.00013-1","title":"Organellar Gβγ signaling—GPCR signaling beyond the cell surface","year":2019,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"G protein-coupled receptor; Cell biology; Golgi apparatus; Organelle; Biology; Signal transduction; G protein; Intracellular; Effector; Mitochondrion; Cell; Function (biology); Endoplasmic reticulum; Biochemistry","score_opus":0.008450118894986548,"score_gpt":0.20392956671227874,"score_spread":0.1954794478172922,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2972947209","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.013373904,0.008405778,0.00021104408,0.00005967277,0.0010934558,0.0009718797,0.00008835254,0.00004555898,0.9757503],"genre_scores_gemma":[0.037575856,0.00034835658,0.0009306628,0.00097106723,0.0011258981,0.000009405124,0.0002552055,0.000282486,0.95850104],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972427,0.00008787233,0.0006342881,0.0009677695,0.0004988986,0.0005684539],"domain_scores_gemma":[0.9979486,0.00006627653,0.00046785432,0.0011295129,0.0002198266,0.00016795017],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00063981296,0.0007697577,0.0006295845,0.00005669791,0.00028166748,0.00013103624,0.0008069768,0.0009219094,0.0011671287],"category_scores_gemma":[0.000015905407,0.00060301565,0.00053252606,0.000020000833,0.00014192918,0.0000034221898,0.00034178005,0.0006797908,0.0004554972],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044940032,0.000013174685,0.0000045209836,0.000120846445,0.00022742178,0.00001785233,0.00015321073,0.00033029748,0.95516145,0.0009223824,0.0009473352,0.042056587],"study_design_scores_gemma":[0.00025044274,0.0001610539,1.4069441e-7,0.000088739886,0.00013047918,0.000012763581,0.0000325117,0.0000113707965,0.40627232,0.0013823559,0.5910952,0.0005625896],"about_ca_topic_score_codex":0.0000011209864,"about_ca_topic_score_gemma":0.0000047832123,"teacher_disagreement_score":0.5901479,"about_ca_system_score_codex":0.000041581163,"about_ca_system_score_gemma":0.0003427269,"threshold_uncertainty_score":0.99974597},"labels":[],"label_agreement":null},{"id":"W2974867339","doi":"10.1074/jbc.ra119.010324","title":"Genetic code expansion and photocross-linking identify different β-arrestin binding modes to the angiotensin II type 1 receptor","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Javna Agencija za Raziskovalno Dejavnost RS; Government of Canada; McGill University","keywords":"Receptor; Angiotensin II; G protein-coupled receptor; Angiotensin receptor; Arrestin; Biology; Cell biology; Signal transduction; Ligand (biochemistry); Chemistry; Genetics","score_opus":0.0220694214589204,"score_gpt":0.2684608323292904,"score_spread":0.24639141087037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2974867339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99789786,0.0009815131,0.0005089983,0.00017909896,0.0002583803,0.00012775593,0.000008895149,0.0000053720323,0.000032141925],"genre_scores_gemma":[0.997105,0.00034148572,0.0016634776,0.00015796939,0.00047948063,0.0000024513442,0.000014978393,0.000013540853,0.00022159514],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989633,0.000044602722,0.00034226888,0.00025975963,0.00016373422,0.0002263261],"domain_scores_gemma":[0.99930245,0.0000315566,0.00021040047,0.00018834358,0.00013590886,0.00013132952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029254053,0.00017110108,0.0002389276,0.00001897739,0.00013548783,0.000055753637,0.00025738394,0.0002244437,0.00016575852],"category_scores_gemma":[0.0001210572,0.00009841971,0.00012102936,0.000072212,0.000046747697,0.0000041794005,0.00023087727,0.0002140685,0.000006899363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015626286,0.000028465794,0.0044360645,0.000012882838,0.00003003524,0.0000035719713,0.000038753573,0.00014728784,0.99395025,0.0000019227593,0.00032670013,0.000867823],"study_design_scores_gemma":[0.00030160835,0.00046881885,0.0021032596,0.0000943039,0.00001304195,0.000085842126,0.00014556883,0.000089547546,0.9925852,0.000055026823,0.0039007012,0.00015709052],"about_ca_topic_score_codex":0.0000016059853,"about_ca_topic_score_gemma":7.0401467e-7,"teacher_disagreement_score":0.0035740011,"about_ca_system_score_codex":0.000019276464,"about_ca_system_score_gemma":0.0000367357,"threshold_uncertainty_score":0.4013439},"labels":[],"label_agreement":null},{"id":"W2975819292","doi":"10.1002/syn.22135","title":"Further in vivo characterization of [<sup>11</sup>C]‐(+)‐PHNO uptake into a retina‐like region of interest in humans","year":2019,"lang":"en","type":"article","venue":"Synapse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Retina; In vivo; Dopamine; Biology; Chemistry; Internal medicine; Neuroscience; Medicine; Genetics","score_opus":0.015534233842905722,"score_gpt":0.22941638280438117,"score_spread":0.21388214896147545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2975819292","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991112,0.000058916397,0.00032759114,0.000055155742,0.00008140473,0.00021895254,0.000006226863,0.0000039593847,0.00013660439],"genre_scores_gemma":[0.99926543,0.00007108364,0.00013109637,0.00003260189,0.00003747903,0.000010657985,0.000062248946,0.000019545356,0.0003698511],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909097,0.000071233786,0.00036283355,0.00026107556,0.000063259846,0.00015064006],"domain_scores_gemma":[0.99947184,0.000006265603,0.00015618153,0.00028669744,0.000052706462,0.000026324702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001951186,0.00011842646,0.00021792724,0.00011072503,0.000008812661,0.0000053025237,0.00015076417,0.00018001108,0.00017482776],"category_scores_gemma":[0.000030889456,0.00011520253,0.0000644531,0.00012149556,0.00003405499,0.000007209735,0.0000662504,0.000074962874,0.000004295611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009999444,0.0000688285,0.012157475,0.000068537935,0.000009440186,0.0000036724055,0.00094816665,0.00003881988,0.98588544,0.0002955686,0.000016154703,0.00040791582],"study_design_scores_gemma":[0.0008740359,0.00043229497,0.0047429856,0.00023617245,0.000006753747,0.0000050668045,0.0008482775,0.00031736816,0.990268,0.00022349876,0.0018516177,0.00019392782],"about_ca_topic_score_codex":0.00010401034,"about_ca_topic_score_gemma":0.00021037948,"teacher_disagreement_score":0.0074144895,"about_ca_system_score_codex":0.000016053113,"about_ca_system_score_gemma":0.00003012939,"threshold_uncertainty_score":0.4697823},"labels":[],"label_agreement":null},{"id":"W2976164311","doi":"10.1177/2472555219875934","title":"Screening of Chemical Libraries Using a Yeast Model of Retinal Disease","year":2019,"lang":"en","type":"article","venue":"SLAS DISCOVERY","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Hospital for Sick Children","keywords":"Rhodopsin; Biology; Retinitis pigmentosa; Yeast; G protein-coupled receptor; Cell biology; Arrestin; Retinal; Genetics; Biochemistry; Signal transduction","score_opus":0.01631999021428888,"score_gpt":0.2293098379326332,"score_spread":0.21298984771834434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2976164311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9579447,0.00025825892,0.0413833,0.0000057686857,0.00004742614,0.00007063223,0.000060865896,0.0000029567236,0.00022608135],"genre_scores_gemma":[0.99314696,0.000008711425,0.0064845853,0.000022400087,0.000058272166,0.0000014181023,0.000045694855,0.000015339852,0.00021661681],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993887,0.000014531175,0.0001699583,0.0001817384,0.00012277973,0.00012228283],"domain_scores_gemma":[0.9996249,0.0000046469386,0.00009536664,0.00020126157,0.000027486114,0.00004634494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059476915,0.000088498295,0.0001405149,0.0000224678,0.000011957962,0.000014728269,0.00011316476,0.000060431794,0.00003528317],"category_scores_gemma":[0.00002335139,0.000082334744,0.000115690826,0.000039382612,0.000053649885,0.000015381933,0.00011645983,0.000041889085,7.279513e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023746923,0.000027932645,0.0031374136,0.000055488308,0.000024096043,3.495285e-7,0.000023491117,0.0045244275,0.9896934,0.0021850858,0.000020627256,0.00007020245],"study_design_scores_gemma":[0.00023553157,0.00005023974,0.00007942468,0.00007255849,0.000020059326,8.322456e-7,0.000060267095,0.024762716,0.9739404,0.00065205694,0.000023248544,0.00010269486],"about_ca_topic_score_codex":0.000006978194,"about_ca_topic_score_gemma":1.4954155e-7,"teacher_disagreement_score":0.035202254,"about_ca_system_score_codex":0.000003103586,"about_ca_system_score_gemma":0.00009978689,"threshold_uncertainty_score":0.33575132},"labels":[],"label_agreement":null},{"id":"W2978274279","doi":"10.1074/jbc.ra119.008233","title":"L-type prostaglandin D synthase regulates the trafficking of the PGD2 DP1 receptor by interacting with the GTPase Rab4","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Prostaglandin D2; Internalization; Rab; G protein-coupled receptor; Cell biology; Receptor; Biology; Intracellular; GTPase; G protein; Immunoprecipitation; Signal transduction; Biochemistry","score_opus":0.009093260361906153,"score_gpt":0.22155990503477152,"score_spread":0.21246664467286536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2978274279","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978858,0.0008936915,0.000060212074,0.0006689977,0.0001921081,0.00013048167,0.000008663485,0.0000030415047,0.00015699147],"genre_scores_gemma":[0.99899495,0.00009977669,0.00011169342,0.0001290254,0.0002455696,0.0000022213328,0.000010566977,0.000011167103,0.00039503438],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902403,0.0001014262,0.00033319037,0.00017231058,0.00018433505,0.00018467478],"domain_scores_gemma":[0.9988012,0.0001425514,0.0005773931,0.0002726403,0.00015737233,0.0000488732],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006059815,0.00015368657,0.00021025915,0.0000060972043,0.000110097375,0.000033474244,0.00050164055,0.00016299967,0.00024164554],"category_scores_gemma":[0.0002953634,0.000055444474,0.00017525064,0.00009815849,0.00014323054,0.0000056652557,0.000104212995,0.00035251208,0.0000013677721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037641774,0.000044841887,0.0014010769,0.000017953893,0.00007274775,0.0000011288275,0.00006541396,0.000102404454,0.9957898,0.0000031555123,0.0017014993,0.00042353166],"study_design_scores_gemma":[0.00035165952,0.0003585806,0.000082734034,0.000107920016,0.000021325031,0.00008657397,0.00084364804,0.000029565243,0.9876458,0.000010133034,0.010364231,0.00009780132],"about_ca_topic_score_codex":0.0000018833141,"about_ca_topic_score_gemma":3.6380106e-7,"teacher_disagreement_score":0.008662731,"about_ca_system_score_codex":0.000015212387,"about_ca_system_score_gemma":0.000059623537,"threshold_uncertainty_score":0.26458493},"labels":[],"label_agreement":null},{"id":"W2980003254","doi":"10.1126/sciadv.aax2518","title":"Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs","year":2019,"lang":"en","type":"article","venue":"Science Advances","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Russian Science Foundation; National Institute on Drug Abuse; Russian Foundation for Basic Research; Agence Nationale de la Recherche; National Science Foundation","keywords":"Antagonist; Mechanism (biology); Chemistry; Leukotriene; Receptor; Pharmacology; Ligand (biochemistry); Mechanism of action; Biophysics; Biochemistry; Biology; Immunology; In vitro; Physics; Asthma","score_opus":0.0030814763784394513,"score_gpt":0.22180473854789662,"score_spread":0.21872326216945717,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980003254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870527,0.0005909021,0.011455506,0.000031551517,0.00041796002,0.00018713999,0.00003530082,0.000009876359,0.00021906773],"genre_scores_gemma":[0.9938212,0.000026212987,0.0057979715,0.00010424164,0.00003837103,0.0000047749045,0.00004927637,0.000009960901,0.0001479578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987784,0.000025405145,0.00020623497,0.0003824166,0.00036384078,0.00024367622],"domain_scores_gemma":[0.9993833,0.000009548934,0.00016380215,0.00025613155,0.00012234626,0.000064900625],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031521198,0.000121389996,0.0001472657,0.000069246256,0.00009203408,0.000025951738,0.00023274003,0.00006237773,0.00020108775],"category_scores_gemma":[0.000042385163,0.0001037556,0.000050066497,0.00028461145,0.00017142728,0.000032910866,0.000050185077,0.00004868971,0.000011212081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018103456,0.000013418924,0.000044235123,0.000029991224,0.0000023326186,8.636584e-8,0.000036241392,0.00031469477,0.9969523,0.00058869884,0.000033411503,0.0019664906],"study_design_scores_gemma":[0.00031963832,0.0003183827,0.0000039498686,0.000041196123,0.0000029104465,0.0000011278801,0.00021007303,0.00025620763,0.9957265,0.00088602485,0.0020957047,0.00013823844],"about_ca_topic_score_codex":0.000005444966,"about_ca_topic_score_gemma":0.0000014350519,"teacher_disagreement_score":0.0067685377,"about_ca_system_score_codex":0.00001640951,"about_ca_system_score_gemma":0.00012895917,"threshold_uncertainty_score":0.42310306},"labels":[],"label_agreement":null},{"id":"W2980231400","doi":"10.1371/journal.pbio.3000477","title":"NF1-cAMP signaling dissociates cell type–specific contributions of striatal medium spiny neurons to reward valuation and motor control","year":2019,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Congressionally Directed Medical Research Programs; National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Medium spiny neuron; Neuroscience; Biology; Dopamine; Striatum; Dopamine receptor D2; Dopamine transporter; Dopaminergic","score_opus":0.01232217242462681,"score_gpt":0.24267251248008923,"score_spread":0.23035034005546243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980231400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944171,0.00058066903,0.003643924,0.00021624536,0.0003076072,0.00054902886,0.00020233728,0.000011050065,0.00007203943],"genre_scores_gemma":[0.998767,0.00011757397,0.00041908378,0.00013776167,0.00018650747,0.000025054067,0.00023650326,0.0000157998,0.000094714764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99894327,0.00013364546,0.00026334403,0.0003347739,0.000081899176,0.00024305977],"domain_scores_gemma":[0.9993042,0.00007114535,0.00012670923,0.00018808183,0.00021823698,0.00009165357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022961729,0.00013604276,0.00025997247,0.00005147396,0.00005367256,0.000013553695,0.00012418794,0.00019894325,0.00018262355],"category_scores_gemma":[0.00017314331,0.00012281218,0.00006680956,0.00007207385,0.00004056444,0.000004276594,0.00006658242,0.000082757884,0.000040069855],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000096152056,0.000046774014,0.003237999,0.000010953251,0.000049080238,1.4970959e-7,0.000038899227,0.00004939335,0.99610996,0.00016818526,0.00010073958,0.000091737915],"study_design_scores_gemma":[0.0010067712,0.0012644454,0.0017708007,0.000014838009,0.00003661871,9.782843e-7,0.00009338266,0.00015219345,0.99353755,0.00038690565,0.0015689423,0.0001665577],"about_ca_topic_score_codex":0.000014588897,"about_ca_topic_score_gemma":0.0000022988079,"teacher_disagreement_score":0.0043499023,"about_ca_system_score_codex":0.000013967097,"about_ca_system_score_gemma":0.000052848365,"threshold_uncertainty_score":0.50081354},"labels":[],"label_agreement":null},{"id":"W2983816334","doi":"10.1016/j.celrep.2019.09.077","title":"Cue-Evoked Dopamine Neuron Activity Helps Maintain but Does Not Encode Expected Value","year":2019,"lang":"en","type":"article","venue":"Cell Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada Foundation for Innovation","keywords":"Dopamine; Optogenetics; Lever; Neuroscience; Psychology; Value (mathematics); Set (abstract data type); Neuron; Midbrain; Computer science; Central nervous system","score_opus":0.006369535805545293,"score_gpt":0.21539111978128345,"score_spread":0.20902158397573817,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2983816334","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99352944,0.00010492185,0.0020697885,0.00004887532,0.0010100271,0.0003060963,0.000007841598,0.000036193025,0.0028868064],"genre_scores_gemma":[0.9854189,0.00005782424,0.00052780635,0.00012199666,0.00027264812,0.000019093373,0.00006997709,0.000042442043,0.013469272],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838346,0.000086321095,0.00029354944,0.0006619368,0.00022743353,0.00034730058],"domain_scores_gemma":[0.9988665,0.000016845115,0.00024591692,0.00067401107,0.000071622235,0.00012511961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002844071,0.00022915857,0.0002361621,0.000041905947,0.00007160442,0.000038589056,0.00012622216,0.0001942204,0.0003214001],"category_scores_gemma":[0.000069268805,0.00018594532,0.00014848002,0.00006121696,0.000028413095,0.0000071910054,0.00013323498,0.0001405775,0.000024225687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000063688516,0.00007276007,0.0010419769,0.000026742398,0.000016385415,0.00014688764,0.000022975197,0.00012515145,0.99787366,0.00002347475,0.00010022951,0.00048606945],"study_design_scores_gemma":[0.0002491543,0.00021399258,0.0005512175,0.000010522814,0.000014899094,0.00008929975,0.00007201624,0.00014481916,0.99155664,0.00012674229,0.006705376,0.00026531905],"about_ca_topic_score_codex":0.00008986646,"about_ca_topic_score_gemma":0.000009560539,"teacher_disagreement_score":0.010582467,"about_ca_system_score_codex":0.00002667692,"about_ca_system_score_gemma":0.00008083638,"threshold_uncertainty_score":0.758263},"labels":[],"label_agreement":null},{"id":"W2984203578","doi":"10.7554/elife.23777.029","title":"Author response: Phosphorylation of β-arrestin2 at Thr383 by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs","year":2017,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"G protein-coupled receptor; Arrestin; Phosphorylation; Internalization; Cell biology; Receptor; Signal transduction; MAPK/ERK pathway; G protein-coupled receptor kinase; Chemistry; Biology; Neuroscience; Biochemistry","score_opus":0.03147654481432479,"score_gpt":0.31605193666321746,"score_spread":0.2845753918488927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2984203578","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.35894042,0.448578,0.07624776,0.049468763,0.01409124,0.010089587,0.01288402,0.00027743497,0.029422775],"genre_scores_gemma":[0.18378675,0.00783729,0.0015139804,0.00042271122,0.000290206,0.00011090259,0.010283447,0.00016103324,0.7955937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972388,0.00024470236,0.0008285405,0.0007077435,0.000668897,0.00031127204],"domain_scores_gemma":[0.9969125,0.00011312239,0.0014587227,0.0009498883,0.00045169672,0.00011410519],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011625537,0.00046500858,0.00076546933,0.00007241139,0.00017097329,0.00002996503,0.0005663857,0.000744755,0.0013463313],"category_scores_gemma":[0.00097190705,0.0004201455,0.00028247092,0.00006864636,0.00014190158,0.000009798409,0.00026245124,0.00024041625,0.000009581825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025252433,0.000037661528,0.000012309761,0.00044050018,0.000083046325,2.805318e-7,0.000011591174,0.000010637136,0.5046617,0.0000103589,0.49260443,0.001874968],"study_design_scores_gemma":[0.00025630384,0.00022803723,0.000017393906,0.0007196876,0.00008617605,0.0000022465345,0.000018511386,0.000014375927,0.58310103,0.00003813437,0.4152503,0.00026780518],"about_ca_topic_score_codex":0.00030655746,"about_ca_topic_score_gemma":0.000041141757,"teacher_disagreement_score":0.7661709,"about_ca_system_score_codex":0.00007745827,"about_ca_system_score_gemma":0.00030316104,"threshold_uncertainty_score":0.99982506},"labels":[],"label_agreement":null},{"id":"W2984394901","doi":"10.1016/j.tips.2019.10.007","title":"Targeting Muscarinic Acetylcholine Receptors for the Treatment of Psychiatric and Neurological Disorders","year":2019,"lang":"en","type":"review","venue":"Trends in Pharmacological Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; H. Lundbeck A/S; National Institutes of Health; Vanderbilt University; Boehringer Ingelheim","keywords":"Muscarinic acetylcholine receptor; Acetylcholine; Neuroscience; Acetylcholine receptor; Psychology; Receptor; Psychiatry; Medicine; Psychotherapist; Pharmacology; Internal medicine","score_opus":0.08483250843352919,"score_gpt":0.40640600037756136,"score_spread":0.3215734919440322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2984394901","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0058288663,0.99248856,0.00006833824,0.00008994184,0.00077874813,0.00060924934,0.000021558806,0.0000067210644,0.00010802078],"genre_scores_gemma":[0.00309159,0.9956041,0.0006488499,0.000041881412,0.0002352995,0.00018246229,0.000040794657,0.000010673638,0.00014436503],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983144,0.00018369578,0.00043395173,0.00061528187,0.00012628874,0.0003263986],"domain_scores_gemma":[0.9992838,0.00029544794,0.00024599605,0.00010970186,0.0000131735505,0.000051896088],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005340488,0.00027917157,0.0006523213,0.000109107226,0.00013898288,0.000022185812,0.00041327698,0.00025160945,0.00019277992],"category_scores_gemma":[0.000038535196,0.00013384862,0.00035238318,0.00042207187,0.0002817567,0.0000034229834,0.000087648354,0.00011926206,0.0000010317797],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028403061,0.0001595283,0.000088332024,0.00013415856,0.00004711786,1.9319863e-7,0.000012200976,0.00012474482,0.00025069353,0.0000338414,0.00022298707,0.9988978],"study_design_scores_gemma":[0.0005006606,0.0029850844,0.000018559016,0.00003666508,0.0003213265,0.0000022033032,0.000019380066,0.00045979655,0.000059607377,0.00004209184,0.9953467,0.00020791205],"about_ca_topic_score_codex":0.000006409534,"about_ca_topic_score_gemma":0.0000055775117,"teacher_disagreement_score":0.9986899,"about_ca_system_score_codex":0.000011951742,"about_ca_system_score_gemma":0.00004501433,"threshold_uncertainty_score":0.5458188},"labels":[],"label_agreement":null},{"id":"W2984734066","doi":"10.7554/elife.28270.032","title":"Author response: Native KCC2 interactome reveals PACSIN1 as a critical regulator of synaptic inhibition","year":2017,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut Universitaire en Santé Mentale de Québec; Lunenfeld-Tanenbaum Research Institute; University of Toronto","funders":"","keywords":"Interactome; Regulator; Neuroscience; Biology; Master regulator; Computational biology; Cell biology; Genetics; Transcription factor; Gene","score_opus":0.03430030966768143,"score_gpt":0.3763906213613974,"score_spread":0.34209031169371595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2984734066","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.32080042,0.24512586,0.025026802,0.31798083,0.025942683,0.010081628,0.00696019,0.00034977315,0.04773179],"genre_scores_gemma":[0.38059887,0.0020060886,0.0029376566,0.0027512033,0.0011595027,0.00017427535,0.0018827689,0.00016245434,0.6083272],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99721843,0.0004695784,0.0007394048,0.000745907,0.0004624567,0.0003642248],"domain_scores_gemma":[0.99721843,0.00017464772,0.0005383932,0.0009734048,0.0009104574,0.00018465555],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015326405,0.00043837688,0.0008657081,0.00013006052,0.00012946194,0.00006482723,0.0003943464,0.00079418457,0.0019370437],"category_scores_gemma":[0.0074129836,0.00037955528,0.00044344022,0.00006842872,0.00021583495,0.00000934033,0.0002946677,0.00037618398,0.00004953919],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036015638,0.000061374936,7.359498e-7,0.0013585573,0.00018016122,0.000020276717,0.000024765142,2.8526946e-7,0.48242366,0.0007280657,0.514026,0.0008159804],"study_design_scores_gemma":[0.000299641,0.0010892492,0.000016102988,0.0075920275,0.00022708096,0.000094886105,0.000042297044,0.000009922784,0.33263177,0.0013747099,0.6560456,0.0005766842],"about_ca_topic_score_codex":0.000036201593,"about_ca_topic_score_gemma":0.000009222092,"teacher_disagreement_score":0.5605954,"about_ca_system_score_codex":0.000052130377,"about_ca_system_score_gemma":0.00039645087,"threshold_uncertainty_score":0.99986565},"labels":[],"label_agreement":null},{"id":"W2986608952","doi":"10.1039/c9md00402e","title":"High affinity rigidified AT<sub>2</sub> receptor ligands with indane scaffolds","year":2019,"lang":"en","type":"article","venue":"MedChemComm","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Stiftelsen för Strategisk Forskning; Vetenskapsrådet; Stiftelsen för Strategisk Forskning; Alzheimer's Society","keywords":"Indane; Chemistry; Agonist; Stereochemistry; Receptor; Combinatorial chemistry; Side chain; Organic chemistry; Biochemistry; Polymer","score_opus":0.004533298004989204,"score_gpt":0.185417161003706,"score_spread":0.1808838629987168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2986608952","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976737,0.00020537397,0.00022611438,0.0001573422,0.0004241726,0.00026711216,0.000020927002,0.000043949178,0.0009813065],"genre_scores_gemma":[0.99655366,0.00011197558,0.0010267152,0.00031686158,0.00032258514,0.000032496115,0.00031160406,0.000059993556,0.0012641135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998477,0.000046741,0.00024989387,0.00053171936,0.00027615507,0.00041849745],"domain_scores_gemma":[0.9989605,0.000022152048,0.00013533227,0.00061216805,0.00009828761,0.00017153952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029968962,0.00029090545,0.0003086392,0.000048355534,0.000128354,0.00004020982,0.00029831482,0.0002942797,0.00049418746],"category_scores_gemma":[0.000024261235,0.00024111626,0.00011410682,0.0001415482,0.00005825285,0.0000073666774,0.00020114826,0.00012421905,0.00032320747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024866068,0.00006891701,0.001637528,0.000025701598,0.00007238636,0.0000028420516,0.00005541356,0.000035885172,0.99376935,0.00013315599,0.002761833,0.0011883014],"study_design_scores_gemma":[0.0011044923,0.0005468242,0.00031074343,0.000035554243,0.000020541042,0.000014638674,0.000057140696,0.000012879122,0.9834874,0.000045046934,0.0139949955,0.00036972328],"about_ca_topic_score_codex":0.00001959123,"about_ca_topic_score_gemma":0.00003872847,"teacher_disagreement_score":0.011233163,"about_ca_system_score_codex":0.00004268519,"about_ca_system_score_gemma":0.000074227486,"threshold_uncertainty_score":0.9832435},"labels":[],"label_agreement":null},{"id":"W2987430397","doi":"10.3389/fendo.2019.00730","title":"Synthetic Peptides as Therapeutic Agents: Lessons Learned From Evolutionary Ancient Peptides and Their Transit Across Blood-Brain Barriers","year":2019,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Peptide; G protein-coupled receptor; Receptor; Secretin family; Transmembrane protein; Cell biology; Neuroscience; Neuropeptide; Biochemistry; Vasoactive intestinal peptide","score_opus":0.016390863730243812,"score_gpt":0.26329136641526585,"score_spread":0.24690050268502203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2987430397","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98492163,0.008791059,0.0036989471,0.0010922101,0.00079963525,0.0002828787,0.00008737941,0.00002556143,0.00030069033],"genre_scores_gemma":[0.9952988,0.0014517299,0.0013241287,0.0009418625,0.00008712092,0.00004168148,0.00008617547,0.00003957021,0.0007289352],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99797434,0.000200672,0.00027414443,0.0007621689,0.00011099071,0.00067768246],"domain_scores_gemma":[0.9992859,0.000045238532,0.00008180347,0.0004181979,0.000037173337,0.0001317122],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016391963,0.00028667547,0.00036555083,0.00008772563,0.00013803183,0.000030884534,0.00029310145,0.0002243258,0.00017738479],"category_scores_gemma":[0.000075440454,0.0002619716,0.00012863647,0.00009412618,0.00024376095,0.0000123285745,0.00012759125,0.00022961729,0.000016590144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002753316,0.00009118061,0.034737516,0.00002526998,0.00036033304,0.00002914282,0.0016782648,0.00055355456,0.94336575,0.00044128043,0.0015753662,0.016866982],"study_design_scores_gemma":[0.006584048,0.0018436039,0.021403043,0.00015770012,0.00013304496,0.00025610783,0.028736992,0.0028988016,0.7671589,0.019249732,0.14989166,0.001686313],"about_ca_topic_score_codex":0.00012388006,"about_ca_topic_score_gemma":0.00003290141,"teacher_disagreement_score":0.17620683,"about_ca_system_score_codex":0.000033448996,"about_ca_system_score_gemma":0.00008000417,"threshold_uncertainty_score":0.99998325},"labels":[],"label_agreement":null},{"id":"W2988031797","doi":"10.7554/elife.12052.019","title":"Author response: Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine","year":2016,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Addiction; Ventral tegmental area; Long-term potentiation; Neuroscience; Vulnerability (computing); Psychology; eIF2; Psychiatry; Pharmacology; Dopaminergic; Medicine; Translation (biology); Dopamine; Biology; Internal medicine; Messenger RNA; Genetics; Receptor; Computer science","score_opus":0.012876154272506749,"score_gpt":0.302213895126211,"score_spread":0.28933774085370423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2988031797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43828893,0.2530944,0.11483135,0.17787467,0.003323506,0.008757321,0.0035938597,0.00006893427,0.00016702736],"genre_scores_gemma":[0.90842307,0.0007947174,0.0007665906,0.0014930848,0.00033260268,0.0002828252,0.0010534524,0.000066670946,0.086787015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982435,0.00039880595,0.0004176786,0.00046426826,0.000276392,0.00019933698],"domain_scores_gemma":[0.99885595,0.0002450506,0.00017475073,0.00039351668,0.00023597897,0.000094734125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012714142,0.0002686898,0.00043868524,0.00003124563,0.00008705215,0.000016713962,0.00018609653,0.00033823485,0.00026165874],"category_scores_gemma":[0.00035408864,0.00016382051,0.00015698177,0.00006052206,0.00008432048,0.0000029845944,0.000041311225,0.00012660756,0.000003346518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045735377,0.000045801735,0.000018391831,0.0004380093,0.00010449215,4.8107523e-7,0.000019346528,0.0000053257518,0.7592818,0.000036396865,0.23291552,0.00667708],"study_design_scores_gemma":[0.0010232646,0.0011442299,0.00029404665,0.00093856646,0.0003500683,0.000007245135,0.0000055780156,0.00005413698,0.50084245,0.0001256822,0.4948103,0.00040443125],"about_ca_topic_score_codex":0.00003596314,"about_ca_topic_score_gemma":0.000020853844,"teacher_disagreement_score":0.4701341,"about_ca_system_score_codex":0.000015217423,"about_ca_system_score_gemma":0.00010095158,"threshold_uncertainty_score":0.6680407},"labels":[],"label_agreement":null},{"id":"W2988818771","doi":"10.1016/j.bcp.2019.113685","title":"Identification of a subset of trace amine-associated receptors and ligands as potential modulators of insulin secretion","year":2019,"lang":"en","type":"article","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Diabetes UK; Research and Development Corporation of Newfoundland and Labrador; Trent University; Memorial University of Newfoundland; Nottingham Trent University","keywords":"Insulin; Endocrinology; Internal medicine; Downregulation and upregulation; Insulin resistance; Receptor; Insulin receptor; Type 2 diabetes; Biology; Diabetes mellitus; Chemistry; Medicine; Biochemistry","score_opus":0.004965065034746922,"score_gpt":0.24685395460296425,"score_spread":0.24188888956821733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2988818771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99815166,0.0010042447,0.0002112265,0.000033301923,0.00033902956,0.0002020199,0.000037022644,0.000005062214,0.00001643267],"genre_scores_gemma":[0.9992925,0.0003177584,0.0000685989,0.000021256963,0.000052759173,0.0000062218896,0.00014333475,0.000013474014,0.00008410126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898803,0.00005242346,0.0004451597,0.00025573027,0.00012456538,0.00013410648],"domain_scores_gemma":[0.9992829,0.00001647998,0.0003676113,0.00011778111,0.00016111211,0.000054135016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024189944,0.00011270598,0.00025025246,0.000059675738,0.000013320843,0.0000024074504,0.000119509736,0.00027336046,0.00016867249],"category_scores_gemma":[0.000062188505,0.000115304014,0.0000889015,0.000113920556,0.00010749663,0.000004484089,0.00006202655,0.000072942945,0.0000019151344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027576674,0.00013600798,0.0005389537,0.00006448413,0.00009215413,2.0964677e-7,0.000048761725,0.00004617522,0.9977522,0.000027129572,0.0008489693,0.00016918681],"study_design_scores_gemma":[0.0010003652,0.0003702209,0.00064698805,0.000013368227,0.000057258105,0.000002672146,0.000053384425,0.0006271056,0.9969321,0.00008000754,0.00011428165,0.00010226245],"about_ca_topic_score_codex":0.000016006901,"about_ca_topic_score_gemma":1.8404488e-7,"teacher_disagreement_score":0.0011408348,"about_ca_system_score_codex":0.000010555209,"about_ca_system_score_gemma":0.00003947276,"threshold_uncertainty_score":0.47019613},"labels":[],"label_agreement":null},{"id":"W2990145185","doi":"10.1186/s13041-019-0524-6","title":"Differential regulation of Cav2.2 channel exon 37 variants by alternatively spliced μ-opioid receptors","year":2019,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Alberta Innovates; National Institute on Drug Abuse; Canada Research Chairs; Peter F. McManus Charitable Trust; National Cancer Institute; National Institutes of Health; Memorial Sloan-Kettering Cancer Center","keywords":"Gene isoform; Agonist; Biology; G protein; Receptor; Alternative splicing; Cell biology; Wild type; DAMGO; Endocrinology; Chemistry; Molecular biology; Pharmacology; Opioid receptor; Mutant; Signal transduction; Biochemistry; Gene","score_opus":0.004756293329859629,"score_gpt":0.2134563687571357,"score_spread":0.20870007542727606,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2990145185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9474541,0.0001896521,0.050935235,0.000101822014,0.00045092692,0.00031104192,0.00003187932,0.000013421459,0.00051190343],"genre_scores_gemma":[0.99685436,0.000027807939,0.00051019085,0.00019723886,0.00010115167,0.000014356089,0.00039896506,0.000044793513,0.0018511228],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986306,0.00011824514,0.00028141524,0.0004541569,0.00025299616,0.00026259164],"domain_scores_gemma":[0.999285,0.000012029713,0.00018418765,0.00035507086,0.00008303092,0.000080721264],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016166606,0.00020863528,0.0002287077,0.000049188773,0.00003987437,0.000022009619,0.00022587147,0.00019990573,0.0004976873],"category_scores_gemma":[0.000050085266,0.00021087444,0.00014296784,0.000093497605,0.00003160119,0.000006484727,0.00010069939,0.00008757896,0.000022220816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006497717,0.000054526474,0.00008067898,0.000023848854,0.00007194499,0.0000010976141,0.000074706026,0.00012446751,0.99656874,0.0003442009,0.0014735482,0.0011172341],"study_design_scores_gemma":[0.0008098422,0.00027044624,0.00036320428,0.000030353098,0.000013572084,0.0000030906283,0.000039793897,0.0007127455,0.9952609,0.00031564952,0.0019397909,0.0002406111],"about_ca_topic_score_codex":0.0000449966,"about_ca_topic_score_gemma":0.0000026310133,"teacher_disagreement_score":0.05042504,"about_ca_system_score_codex":0.000017154096,"about_ca_system_score_gemma":0.000034100023,"threshold_uncertainty_score":0.859921},"labels":[],"label_agreement":null},{"id":"W2991632990","doi":"10.1038/s41596-019-0259-y","title":"Small-scale approach for precrystallization screening in GPCR X-ray crystallography","year":2019,"lang":"en","type":"article","venue":"Nature Protocols","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; U.S. Department of Health and Human Services","keywords":"Sf9; G protein-coupled receptor; Absorbance; Computational biology; Receptor; Drug discovery; Chromatography; Biology; Chemistry; Spodoptera; Cell biology; Biophysics; Biochemistry; Recombinant DNA","score_opus":0.014813577834405603,"score_gpt":0.2714282231843341,"score_spread":0.2566146453499285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2991632990","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14389625,0.0002720519,0.72087896,0.000041615865,0.00010792062,0.13214684,0.000031167183,0.000045384055,0.0025798446],"genre_scores_gemma":[0.7085326,0.0000056257986,0.19033384,0.0002927036,0.00028490942,0.09919365,0.00054123974,0.00006758694,0.0007478631],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99889207,0.000050566643,0.00021438871,0.00044929283,0.00012755538,0.00026615273],"domain_scores_gemma":[0.9994846,0.000010718731,0.000094095594,0.00026143363,0.000098554534,0.000050619918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036338938,0.00016498096,0.0001755366,0.00008624665,0.00004554399,0.000045959423,0.00021523618,0.000541121,0.000027026406],"category_scores_gemma":[0.0000332831,0.0001518967,0.00012873541,0.00016625044,0.000014500274,0.00000670866,0.000055543613,0.00019954378,6.2128026e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002817532,0.0000940062,0.00935102,0.00017442355,0.000024257664,2.214146e-7,0.000040623792,0.002462348,0.98553073,0.00024512218,0.00017772762,0.0016177599],"study_design_scores_gemma":[0.005433836,0.0012510059,0.0027349107,0.00028399314,0.000020076019,0.000005860334,0.00022869658,0.008740377,0.7580037,0.0007177423,0.22165816,0.0009216317],"about_ca_topic_score_codex":0.0000028859276,"about_ca_topic_score_gemma":0.000008917199,"teacher_disagreement_score":0.56463635,"about_ca_system_score_codex":0.000007643498,"about_ca_system_score_gemma":0.00003409304,"threshold_uncertainty_score":0.6194168},"labels":[],"label_agreement":null},{"id":"W2993525876","doi":"","title":"Lactate receptor GPR81 modulates the integrated stress response in the developing outer retina","year":2018,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Children's Hospital; Centre Hospitalier Universitaire Sainte-Justine; McGill University Health Centre; Université de Montréal","funders":"","keywords":"Retina; Cell biology; Chemistry; Receptor; Neuroscience; Biology; Biochemistry","score_opus":0.033082609937736165,"score_gpt":0.3243567822946189,"score_spread":0.29127417235688274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2993525876","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99737704,0.00005780133,0.00006796949,0.0016466418,0.00031777774,0.00027013003,0.000008796663,0.000009675524,0.00024416498],"genre_scores_gemma":[0.9968791,0.0000066487733,0.0017993536,0.00092646986,0.00015411459,0.000044587596,0.0000123579275,0.000013594192,0.00016375938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974656,0.0008841927,0.00027907142,0.0005899815,0.000283656,0.0004975082],"domain_scores_gemma":[0.99899966,0.00015230979,0.00013941474,0.0003383354,0.00028556547,0.000084732186],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0029637602,0.00021326389,0.00015540645,0.000088617475,0.00054178317,0.000101484,0.0009909505,0.00013598269,0.00008553222],"category_scores_gemma":[0.0012518145,0.00012096173,0.000046587455,0.0007899486,0.0037338398,0.000022746095,0.00025895805,0.00024518993,0.00003557497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019351834,0.000022591443,0.0026280226,0.0000020934958,0.000008554246,0.000016667469,0.0017678068,0.000013983454,0.99498224,0.00014052754,0.00009432407,0.00012965851],"study_design_scores_gemma":[0.00016035688,0.00093692984,0.01942768,0.000046148896,0.0000039367887,0.000089092406,0.0016398896,0.00030443878,0.9752594,0.0011702707,0.00076623226,0.00019559257],"about_ca_topic_score_codex":0.0000813599,"about_ca_topic_score_gemma":0.000014021219,"teacher_disagreement_score":0.01972282,"about_ca_system_score_codex":0.000050641636,"about_ca_system_score_gemma":0.0004183329,"threshold_uncertainty_score":0.9989774},"labels":[],"label_agreement":null},{"id":"W2993584545","doi":"","title":"Different Structures of Aβ1-40 Assemblies Induce Distinctive Primary RPE Cell Responses in vitro","year":2014,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"In vitro; Primary (astronomy); Cell biology; Chemistry; Biophysics; Biology; Physics; Biochemistry; Astrophysics","score_opus":0.023629583224294114,"score_gpt":0.30104294696957157,"score_spread":0.2774133637452775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2993584545","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984086,0.00009935181,0.00009589622,0.000040233524,0.00020458279,0.00017904314,0.000014723484,0.0000071067343,0.0009504364],"genre_scores_gemma":[0.9980416,0.0000046056275,0.0016021988,0.00011461314,0.000070991555,0.000022279572,0.00002527646,0.00001484957,0.0001035293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978717,0.00040791245,0.00033281062,0.00065769715,0.0003133275,0.00041653],"domain_scores_gemma":[0.999035,0.00014176349,0.0002376351,0.0002625124,0.00016161017,0.00016145516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00072743424,0.00024204352,0.00033262445,0.00017888691,0.00015603077,0.000027749498,0.00049111026,0.00017453538,0.000035174657],"category_scores_gemma":[0.0007705836,0.0001999111,0.00006510651,0.00036365344,0.0020161471,0.000019442532,0.00033471893,0.00019595216,0.0000022979107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021144054,0.00008196633,0.009933198,0.000017069951,0.0000075732455,0.000006738093,0.00024134142,0.000024466024,0.98910534,0.00013003133,0.0000060536013,0.00023474928],"study_design_scores_gemma":[0.0002764945,0.000747882,0.1281114,0.000015857615,0.000006014768,0.0000207989,0.00016725333,0.00006560857,0.8670105,0.0033704308,0.000018492727,0.00018929817],"about_ca_topic_score_codex":0.000058974758,"about_ca_topic_score_gemma":0.0000027992332,"teacher_disagreement_score":0.122094914,"about_ca_system_score_codex":0.000049577517,"about_ca_system_score_gemma":0.00025602157,"threshold_uncertainty_score":0.8152138},"labels":[],"label_agreement":null},{"id":"W2993915081","doi":"10.1038/s41467-019-13348-2","title":"Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of General Medical Sciences; Russian Science Foundation; Centre National de la Recherche Scientifique; European Synchrotron Radiation Facility; Agence Nationale de la Recherche; Université de Sherbrooke; Canadian Institutes of Health Research; French Infrastructure for Integrated Structural Biology; University of Southern California; Ministry of Science and Higher Education of the Russian Federation; U.S. Department of Health and Human Services","keywords":"Ligand (biochemistry); Asthma; Receptor; Mutagenesis; Leukotriene; Computational biology; Chemistry; Biology; Mutation; Genetics; Gene; Immunology","score_opus":0.008435161453749984,"score_gpt":0.262565322957849,"score_spread":0.254130161504099,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2993915081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949982,0.004037347,0.00004699922,0.00033605742,0.00008462226,0.00018089879,0.000027815178,0.00000551222,0.00028252904],"genre_scores_gemma":[0.99762505,0.00033413642,0.0016237886,0.00006147349,0.000016495462,0.000013405548,0.00020364524,0.0000092794035,0.00011273921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946165,0.00007966448,0.00014067402,0.00015716052,0.00006923261,0.00009163561],"domain_scores_gemma":[0.9991574,0.000044374647,0.0000659429,0.000582012,0.00008765544,0.00006256233],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012258519,0.00007765759,0.00010451216,0.000056471137,0.00006689145,0.000010683041,0.00024033317,0.00014459224,0.000017519069],"category_scores_gemma":[0.00015460748,0.0000751714,0.00003472878,0.00015360396,0.00005585138,0.000007058994,0.00014272706,0.00021542677,0.0000012538811],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058824542,0.000060973016,0.105397776,0.000029759263,0.00003779994,2.2593254e-7,0.00020141854,0.00019434525,0.88681513,0.0049809753,0.0002340846,0.0019886931],"study_design_scores_gemma":[0.0023044297,0.00037204378,0.17126462,0.00013867418,0.00009364687,0.000011468352,0.0006903601,0.0050808922,0.79445535,0.0031506654,0.021678582,0.00075927837],"about_ca_topic_score_codex":0.000025281854,"about_ca_topic_score_gemma":0.00018730998,"teacher_disagreement_score":0.09235979,"about_ca_system_score_codex":0.00001192233,"about_ca_system_score_gemma":0.00007621311,"threshold_uncertainty_score":0.3065401},"labels":[],"label_agreement":null},{"id":"W2994951303","doi":"10.1101/2019.12.13.876250","title":"Medical relevance of common protein-altering variants in GPCR genes across 337,205 individuals in the UK Biobank","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"G protein-coupled receptor; Biobank; Biology; Phenome; Phenotype; Computational biology; Receptor; Genetics; Gene; Bioinformatics; Genome-wide association study; Single-nucleotide polymorphism; Genotype","score_opus":0.012944320183728745,"score_gpt":0.2529974646338606,"score_spread":0.24005314445013184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2994951303","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945275,0.0027308632,0.0008289208,0.000112823625,0.000560332,0.001038242,0.00017288358,0.000021186146,0.0000072423495],"genre_scores_gemma":[0.9969436,0.0008243383,0.0014764266,0.00017357667,0.00030290367,0.00019517739,0.0000026632695,0.00007808337,0.0000032291412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965973,0.0003649776,0.00086169806,0.0009304695,0.00061110174,0.0006344856],"domain_scores_gemma":[0.9978899,0.00005413202,0.0004911608,0.0012917275,0.00015215165,0.00012095106],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0022221813,0.00047301408,0.0006598445,0.00013625024,0.000071409064,0.00009965905,0.0011002579,0.0009691349,0.00005913327],"category_scores_gemma":[0.0003788784,0.00041799902,0.00015188697,0.00034501267,0.0001258026,0.000010780851,0.0009100073,0.0007897324,0.000007984142],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039913408,0.00014970345,0.028831419,0.0003297079,0.000057602265,0.000041827458,0.00003649194,0.00027728235,0.970018,0.00017333076,0.00003119794,0.000013476479],"study_design_scores_gemma":[0.0008027408,0.00012272249,0.053502295,0.0010319607,0.000016982933,1.1790153e-7,0.000020337506,0.00024107563,0.9419625,0.000006791869,0.0017257223,0.0005667556],"about_ca_topic_score_codex":0.0002086837,"about_ca_topic_score_gemma":0.00007944171,"teacher_disagreement_score":0.028055549,"about_ca_system_score_codex":0.000052727148,"about_ca_system_score_gemma":0.00048054196,"threshold_uncertainty_score":0.9998272},"labels":[],"label_agreement":null},{"id":"W2995293438","doi":"10.1016/j.pneurobio.2019.101734","title":"Deciphering midbrain mechanisms underlying prepulse inhibition of startle","year":2019,"lang":"en","type":"article","venue":"Progress in Neurobiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Prepulse inhibition; Neuroscience; Pedunculopontine Tegmental Nucleus; Cholinergic; Pedunculopontine nucleus; Midbrain; Inhibitory postsynaptic potential; Startle response; Glutamatergic; Psychology; Dopamine; Cholinergic neuron; Schizophrenia (object-oriented programming); Medicine; Central nervous system; Receptor; Glutamate receptor; Internal medicine; Parkinson's disease","score_opus":0.014671129571647847,"score_gpt":0.2647541098456199,"score_spread":0.2500829802739721,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995293438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99637437,0.00041766337,0.0024027,0.00003309808,0.00029687744,0.00028170826,0.000005724362,0.000012235725,0.00017560479],"genre_scores_gemma":[0.99686736,0.000040289233,0.0028283093,0.00008339763,0.000021571446,0.00002938864,0.000049142047,0.000022036229,0.000058481754],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895793,0.00010991347,0.00026646443,0.0003561954,0.00006079455,0.00024872654],"domain_scores_gemma":[0.99956375,0.000019089433,0.000116373274,0.0002319179,0.000036961374,0.00003187744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022752598,0.00012743994,0.00018733321,0.000063019084,0.00002104846,0.000008441029,0.00012150421,0.00016225914,0.00012447512],"category_scores_gemma":[0.000024765204,0.00012476213,0.000061170635,0.00008654721,0.0000504218,0.000005103142,0.0001251444,0.00009707449,0.000007974771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007276786,0.000047102647,0.011641079,0.000036431615,0.00001082223,0.0000026542377,0.000038966744,0.000118043536,0.98475766,0.0009228362,0.000008630085,0.0023430036],"study_design_scores_gemma":[0.00062342617,0.00065343536,0.0022144218,0.00005118664,0.0000041997305,0.000011167603,0.00007571919,0.00022841664,0.99402356,0.001631128,0.0003235579,0.00015977872],"about_ca_topic_score_codex":0.000004383685,"about_ca_topic_score_gemma":0.000010836652,"teacher_disagreement_score":0.009426657,"about_ca_system_score_codex":0.000009203392,"about_ca_system_score_gemma":0.00002684125,"threshold_uncertainty_score":0.50876516},"labels":[],"label_agreement":null},{"id":"W2995994433","doi":"10.1038/s41589-019-0427-y","title":"Tailor-made GPCRs","year":2019,"lang":"en","type":"letter","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"In silico; G protein-coupled receptor; Computational biology; Allosteric regulation; Sequence (biology); Biology; Bioinformatics; Receptor; Genetics; Gene","score_opus":0.006122944005216174,"score_gpt":0.24324307156761166,"score_spread":0.23712012756239548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2995994433","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14164914,0.03498689,0.0015524958,0.7792419,0.016615912,0.002174354,0.0013608071,0.00030841943,0.022110049],"genre_scores_gemma":[0.049414925,0.00032613525,0.001202727,0.91032594,0.018029971,0.000047219477,0.01381272,0.00014823746,0.006692139],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977238,0.000093821596,0.00032204197,0.001050146,0.00015920002,0.0006509564],"domain_scores_gemma":[0.99888855,0.0000631403,0.00018162144,0.00068763556,0.00011606334,0.00006299089],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00013049674,0.0004933937,0.0005302611,0.00006999007,0.000038752492,0.0000237708,0.0007233946,0.010080769,0.00051505264],"category_scores_gemma":[0.00021160401,0.00041564132,0.00036429928,0.00008348174,0.00012874149,0.0000016298926,0.00028415915,0.003790101,0.00018629551],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017718241,0.000006257949,0.000014696945,0.000027594504,0.000060673774,0.0000077493305,0.0000015506895,1.8182115e-7,0.52255464,0.00003844053,0.47692803,0.00034246157],"study_design_scores_gemma":[0.0001758056,0.00008684277,5.484056e-7,0.000013001676,0.000019495053,0.000020000924,0.0000014090166,0.0000014669403,0.43391037,0.000281455,0.56518805,0.00030156306],"about_ca_topic_score_codex":0.0000039549946,"about_ca_topic_score_gemma":3.2254124e-7,"teacher_disagreement_score":0.131084,"about_ca_system_score_codex":0.000034529003,"about_ca_system_score_gemma":0.00010361527,"threshold_uncertainty_score":0.99982953},"labels":[],"label_agreement":null},{"id":"W2996373543","doi":"10.1016/bs.pmbts.2019.11.001","title":"Exploring functional consequences of GPCR oligomerization requires a different lens","year":2019,"lang":"en","type":"review","venue":"Progress in molecular biology and translational science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"G protein-coupled receptor; Allosteric regulation; Computational biology; Context (archaeology); Receptor; Biology; Signal transduction; Neuroscience; Chemistry; Cell biology; Biochemistry","score_opus":0.11579339630373128,"score_gpt":0.3524665566410458,"score_spread":0.23667316033731453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2996373543","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.019241998,0.9734624,0.006600817,0.000023740553,0.00023491478,0.00034349386,0.000032762888,0.0000049699556,0.00005492799],"genre_scores_gemma":[0.16535498,0.8331467,0.0010903559,0.000011410939,0.000043773594,0.000108769804,0.00022774684,0.000012317256,0.000003936138],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985277,0.000114536866,0.00039161593,0.00054933765,0.0001845586,0.0002322469],"domain_scores_gemma":[0.9995167,0.000031706757,0.00018560089,0.00015290073,0.00007157391,0.00004148549],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034907457,0.0002174103,0.0004622024,0.00021099365,0.00007832113,0.000018391725,0.00021349154,0.00018622968,0.00001532892],"category_scores_gemma":[0.000025529991,0.00017150167,0.00012499097,0.00027419013,0.0009649644,0.00001768955,0.00006342679,0.000120883735,8.874037e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054463548,0.00010895677,0.004683653,0.002483181,0.00014757918,0.00000471619,0.000064858425,0.000067111614,0.19224526,0.06315348,6.178027e-7,0.7369861],"study_design_scores_gemma":[0.004758516,0.0036333671,0.008907105,0.021892836,0.001597454,0.00047232487,0.00020565308,0.00062539085,0.5752821,0.021486923,0.35494435,0.006193958],"about_ca_topic_score_codex":0.0000028042296,"about_ca_topic_score_gemma":0.0000018541102,"teacher_disagreement_score":0.73079216,"about_ca_system_score_codex":0.000008238817,"about_ca_system_score_gemma":0.00026580284,"threshold_uncertainty_score":0.69936347},"labels":[],"label_agreement":null},{"id":"W2997037077","doi":"10.1074/jbc.ra119.011461","title":"Molecular basis for activation and biased signaling at the thrombin-activated GPCR proteinase activated receptor-4 (PAR4)","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Thrombin; G protein-coupled receptor; Protease-activated receptor; Receptor; Chemistry; Thrombin receptor; Cell biology; Biochemistry; Biology; Platelet; Immunology","score_opus":0.01998865678525053,"score_gpt":0.2461948161411933,"score_spread":0.22620615935594277,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2997037077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99751043,0.0003051533,0.0013411033,0.0002818537,0.00008198503,0.00035542378,0.000016600454,0.000008354837,0.0000990738],"genre_scores_gemma":[0.998413,0.00008938125,0.0008520267,0.00018064532,0.00020286036,0.00002045917,0.00007369072,0.000021504893,0.00014640157],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988015,0.00008303644,0.00038822085,0.0003074967,0.00016999792,0.0002497249],"domain_scores_gemma":[0.99888,0.00011257328,0.00047135248,0.00020304395,0.00022373686,0.00010929119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049116847,0.00021509864,0.00029008472,0.000019552494,0.00012456586,0.000039440918,0.0002140884,0.00034493092,0.00044175997],"category_scores_gemma":[0.00043933475,0.00013365947,0.00020599407,0.00009522647,0.00007878451,0.000011190724,0.00009634397,0.00022016167,0.0000021018072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00077625597,0.00005971453,0.0001772196,0.000039539616,0.00011647361,0.0000015731335,0.000016567341,0.000120141565,0.9979193,0.000005969679,0.00019473952,0.00057246594],"study_design_scores_gemma":[0.0008584887,0.0005776074,0.00005623619,0.00007623912,0.000020049942,0.000037840997,0.00016069529,0.000023996638,0.99501866,0.00008119822,0.002894698,0.00019430993],"about_ca_topic_score_codex":0.000002065823,"about_ca_topic_score_gemma":7.503112e-8,"teacher_disagreement_score":0.0029006999,"about_ca_system_score_codex":0.000053504027,"about_ca_system_score_gemma":0.00006422775,"threshold_uncertainty_score":0.54504746},"labels":[],"label_agreement":null},{"id":"W2999561768","doi":"10.1101/2020.01.08.898338","title":"Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Novo Nordisk Fonden; Oticon Fonden; Novo Nordisk; H. Lundbeck A/S; Lundbeckfonden; European Commission; Toyota Foundation","keywords":"Internalization; Beta adrenergic receptor kinase; G protein-coupled receptor kinase; G protein-coupled receptor; Arrestin; Cell biology; CRISPR; Agonist; Gene knockdown; Receptor; Biology; Chemistry; Pharmacology; Signal transduction; Biochemistry; Gene","score_opus":0.027425326497897216,"score_gpt":0.25330448489543955,"score_spread":0.22587915839754233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999561768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98691714,0.0030382115,0.008335777,0.000068413334,0.0008201495,0.00072160555,0.000070500224,0.000026496418,0.0000017269506],"genre_scores_gemma":[0.9948793,0.0010741494,0.0033264249,0.000086847904,0.00049845036,0.000056828958,0.0000017358187,0.00007408699,0.0000021573426],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980529,0.00015918577,0.00052627095,0.00077374355,0.00020171942,0.00028616574],"domain_scores_gemma":[0.9987046,0.00003660584,0.0004450767,0.00043966467,0.00023957225,0.00013448876],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047904992,0.00037616512,0.00041111055,0.00010748732,0.000107427324,0.00011728238,0.00026821683,0.00037077747,0.000015453208],"category_scores_gemma":[0.00024375776,0.00033940785,0.00007825944,0.00019394713,0.00010013448,0.000011325349,0.0005937338,0.00036713565,7.3800607e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056101606,0.00003303836,0.0051187663,0.0002768788,0.000071483,0.000004524887,0.00006497701,0.0002211632,0.9940069,0.0000988458,0.000037097645,0.000010259496],"study_design_scores_gemma":[0.00033991822,0.00008839432,0.0021463532,0.0005122932,0.000059355774,4.904255e-8,0.000049650826,0.0024953596,0.9928004,0.000008135579,0.0011389563,0.00036109192],"about_ca_topic_score_codex":0.00008471907,"about_ca_topic_score_gemma":0.000018111283,"teacher_disagreement_score":0.007962199,"about_ca_system_score_codex":0.000043337892,"about_ca_system_score_gemma":0.00015156392,"threshold_uncertainty_score":0.99990577},"labels":[],"label_agreement":null},{"id":"W3000029919","doi":"10.1007/s13311-019-00828-y","title":"GPCR and Alcohol-Related Behaviors in Genetically Modified Mice","year":2020,"lang":"en","type":"review","venue":"Neurotherapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"G protein-coupled receptor; Neuroscience; Computational biology; Biology; Drug discovery; Neuropharmacology; Crosstalk; Bioinformatics; Medicine; Receptor; Genetics","score_opus":0.0462636363418782,"score_gpt":0.32082997115157064,"score_spread":0.27456633480969245,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3000029919","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001365617,0.9973009,0.00020113886,0.000032406184,0.00019871931,0.0006178263,0.000026671223,0.000018457264,0.00023823726],"genre_scores_gemma":[0.0007482708,0.9979913,0.0003617527,0.0003601591,0.00010833405,0.00005035268,0.00008337175,0.00012284493,0.00017358536],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981995,0.00018640995,0.00053205696,0.00064911885,0.00013867024,0.00029419368],"domain_scores_gemma":[0.9993814,0.00002462171,0.00015406874,0.00028964898,0.000025673653,0.00012458146],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00011184082,0.0004117204,0.0007612698,0.00008046582,0.000039474682,0.000045657016,0.000268874,0.0006060098,0.00003512575],"category_scores_gemma":[0.000017903807,0.0003827006,0.00022206477,0.00016838562,0.000059810412,0.0000017308769,0.00008942772,0.00040383975,0.0000118582675],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015191307,0.000054260476,0.000006196154,0.00073442934,0.000102351885,0.00003894425,0.000037665177,0.000009016272,0.030957302,0.00014502277,0.000028447515,0.9678712],"study_design_scores_gemma":[0.0003613539,0.00024656832,0.0000034834547,0.0004093539,0.0002807373,0.00006153637,0.000005091355,0.000077561715,0.0014808604,0.00003993605,0.99660736,0.00042617973],"about_ca_topic_score_codex":0.000004833434,"about_ca_topic_score_gemma":0.0000038829157,"teacher_disagreement_score":0.9965789,"about_ca_system_score_codex":0.000014241948,"about_ca_system_score_gemma":0.00012475769,"threshold_uncertainty_score":0.9998625},"labels":[],"label_agreement":null},{"id":"W3003623154","doi":"10.69645/knqc9980","title":"What can we learn from conformational profiling of GPCRs?","year":2020,"lang":"en","type":"article","venue":"The biomedical & life sciences collection.","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Profiling (computer programming); G protein-coupled receptor; Computational biology; Chemistry; Computer science; Biology; Receptor; Biochemistry; Programming language","score_opus":0.02287072544558457,"score_gpt":0.2582954980852935,"score_spread":0.23542477263970893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3003623154","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8950638,0.003741288,0.07373593,0.02225796,0.003202148,0.00064266945,0.00008989754,0.00005331464,0.001212963],"genre_scores_gemma":[0.9949604,0.00036807373,0.0019177276,0.0018310866,0.0005972027,0.000014769198,0.00006831333,0.000006464015,0.00023594227],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987789,0.00006524694,0.00027620807,0.00025461684,0.00044606996,0.0001789574],"domain_scores_gemma":[0.999485,0.000044811513,0.00011930438,0.00009655433,0.00007735059,0.00017697785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033779265,0.000094051626,0.00012577382,0.00003778149,0.0003406252,0.00006980247,0.00032386967,0.00009699388,0.0003488142],"category_scores_gemma":[0.00013646758,0.00006510558,0.00007420487,0.0005072292,0.00042204926,0.000016839615,0.00009680581,0.00010541822,0.000009965718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001134684,0.000072520794,0.000450332,0.00003030496,0.00009600782,0.0000010801926,0.0017449749,0.00071047654,0.97693723,0.00086050644,0.014208183,0.0047749323],"study_design_scores_gemma":[0.00169551,0.0022394073,0.00025909935,0.00010986251,0.000058393645,0.00001606318,0.020935092,0.06519222,0.7205625,0.0029636954,0.18536171,0.0006064008],"about_ca_topic_score_codex":0.0000528492,"about_ca_topic_score_gemma":0.000019680052,"teacher_disagreement_score":0.25637466,"about_ca_system_score_codex":0.000009581291,"about_ca_system_score_gemma":0.00044154705,"threshold_uncertainty_score":0.3819271},"labels":[],"label_agreement":null},{"id":"W3004104740","doi":"10.7554/elife.50519","title":"The orphan receptor GPR88 blunts the signaling of opioid receptors and multiple striatal GPCRs","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"H2020 Marie Skłodowska-Curie Actions; Laboratoire d'Excellence MAbImprove; Centre National de la Recherche Scientifique; Agence Nationale de la Recherche; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; Fonds Unique Interministériel; Institut National de la Santé et de la Recherche Médicale","keywords":"G protein-coupled receptor; Receptor; Pharmacology; Orphan receptor; Opioid; Chemistry; Cell biology; Biology; Biochemistry; Gene","score_opus":0.013269910628334209,"score_gpt":0.22249570817565864,"score_spread":0.20922579754732443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004104740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99549925,0.0021368328,0.0008273994,0.00081517285,0.0003756982,0.0002349403,0.000028403203,0.0000123616865,0.000069926326],"genre_scores_gemma":[0.99731797,0.0008904965,0.00057897985,0.00045486476,0.00056146766,0.000008990656,0.000040913234,0.000023549497,0.00012277723],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989478,0.000097291384,0.0002654821,0.00026722907,0.00020903054,0.00021317549],"domain_scores_gemma":[0.9993824,0.000082559156,0.00013359006,0.0002146741,0.00007764307,0.000109133674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036379712,0.0001437874,0.00014347916,0.000010023594,0.00024390047,0.00004363498,0.00028019954,0.0000999101,0.000079392616],"category_scores_gemma":[0.00037764086,0.00008728983,0.00008898558,0.00008881925,0.000104076724,0.000004437771,0.00015448357,0.0001197527,0.00000997799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011597552,0.000010174655,0.00069904985,0.000011232788,0.000056575675,2.1150035e-7,0.00035780453,0.00009216156,0.99156404,0.00009292759,0.0035317703,0.003468055],"study_design_scores_gemma":[0.00037132125,0.0002044843,0.000051105828,0.000011940897,0.000012592351,8.941169e-7,0.00077167916,0.00028183442,0.87003547,0.000012473781,0.12813099,0.00011519797],"about_ca_topic_score_codex":0.00001956892,"about_ca_topic_score_gemma":0.000006836347,"teacher_disagreement_score":0.12459922,"about_ca_system_score_codex":0.0000050875083,"about_ca_system_score_gemma":0.00005138327,"threshold_uncertainty_score":0.3559576},"labels":[],"label_agreement":null},{"id":"W3004182907","doi":"10.1523/jneurosci.1919-19.2020","title":"Cholecystokinin-Expressing Interneurons of the Medial Prefrontal Cortex Mediate Working Memory Retrieval","year":2020,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Parvalbumin; Interneuron; Neuroscience; Optogenetics; Prefrontal cortex; Cholecystokinin; Population; Working memory; Inhibitory postsynaptic potential; Schizophrenia (object-oriented programming); Cognition; Sensory system; Psychology; Biology; Medicine; Receptor","score_opus":0.025544301788223867,"score_gpt":0.24822036003501022,"score_spread":0.22267605824678635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004182907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99582165,0.00016968818,0.0018526406,0.00034485722,0.0016178045,0.000056507997,0.0000027885749,0.000002472242,0.000131559],"genre_scores_gemma":[0.9983634,0.00005105061,0.00024007537,0.00080424926,0.0004964921,2.3063478e-7,2.9372634e-7,0.0000111118015,0.000033096185],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99877185,0.00009405219,0.00036587496,0.00018881506,0.00041838974,0.00016102924],"domain_scores_gemma":[0.999148,0.000018261604,0.00049562345,0.00013929581,0.00007517319,0.00012363933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002654792,0.00009824078,0.00015852437,0.000026538604,0.000076509445,0.00003300233,0.0006372361,0.00005351426,0.000010634582],"category_scores_gemma":[0.00060795865,0.000067319845,0.00015284297,0.0001583644,0.00015725063,0.000012542183,0.0002098319,0.00023690835,3.6364855e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000110649926,0.000015328424,0.00042288724,0.0000046137684,0.0000028515888,0.000010035207,0.0001907312,0.00022187058,0.99860364,0.000003189562,0.00010294673,0.0003112594],"study_design_scores_gemma":[0.00037195094,0.00049181306,0.0055822334,0.000049083592,0.00001484379,0.00008510457,0.00006722666,0.0005027617,0.99090785,0.000011357827,0.0018400846,0.00007568578],"about_ca_topic_score_codex":5.737751e-7,"about_ca_topic_score_gemma":5.186878e-7,"teacher_disagreement_score":0.0076957825,"about_ca_system_score_codex":0.0000075078374,"about_ca_system_score_gemma":0.00012990732,"threshold_uncertainty_score":0.27452236},"labels":[],"label_agreement":null},{"id":"W3004694155","doi":"10.1016/j.bpj.2019.11.2880","title":"Molecular Dynamics Simulations of the A2A G-Protein Coupled Receptor","year":2020,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Molecular dynamics; Context (archaeology); Force field (fiction); Chemistry; POPC; Computational biology; Lipid bilayer; Receptor; Computational chemistry; Membrane; Biology; Computer science; Biochemistry; Artificial intelligence","score_opus":0.009444218912847177,"score_gpt":0.22744693741683872,"score_spread":0.21800271850399155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3004694155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97096175,0.000029364563,0.027710414,0.0010160482,0.00011363046,0.00009918171,0.00001857218,0.00000405898,0.000046980636],"genre_scores_gemma":[0.9984077,0.0000053429308,0.0008623319,0.0002817076,0.00037905647,0.0000014651906,0.000014557185,0.00001563237,0.000032204825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992772,0.00006129204,0.00020063798,0.00013764756,0.00018940307,0.00013384434],"domain_scores_gemma":[0.99950826,0.0000060004027,0.00013294422,0.00014135009,0.00010201286,0.000109444016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054038446,0.00009826233,0.0001207375,0.0000094689485,0.00009450048,0.000029150038,0.00024295908,0.00007747682,0.00008533298],"category_scores_gemma":[0.0000891936,0.000069381924,0.00019586178,0.00011119465,0.000051724623,0.0000040114232,0.00008289158,0.00015979492,0.0000053003646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034964538,0.00003258745,0.000024060093,0.000005299733,0.000034283436,9.557469e-7,0.000025746629,0.0020869032,0.9965455,0.00088173774,0.000051474242,0.0002764899],"study_design_scores_gemma":[0.00027630728,0.00018786128,0.000031650306,0.000013256208,0.000014929988,0.000003230496,0.000042482698,0.029611712,0.9688914,0.00013101737,0.00070279784,0.00009334459],"about_ca_topic_score_codex":0.0000022668057,"about_ca_topic_score_gemma":6.3976216e-7,"teacher_disagreement_score":0.027654089,"about_ca_system_score_codex":0.000015135326,"about_ca_system_score_gemma":0.000081856866,"threshold_uncertainty_score":0.28293127},"labels":[],"label_agreement":null},{"id":"W3005219635","doi":"10.1016/j.bpj.2019.11.1088","title":"Dynamic Fingerprinting of the A2A Adenosine Receptor in Different Ligand-biased States","year":2020,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Förster resonance energy transfer; Chemistry; Adenosine A2A receptor; Biophysics; G protein-coupled receptor; Single-molecule FRET; Ligand (biochemistry); Molecular dynamics; Agonist; Adenosine receptor; Receptor; Stereochemistry; Fluorescence; Biochemistry; Computational chemistry; Biology","score_opus":0.009218023800393339,"score_gpt":0.22679494085255214,"score_spread":0.2175769170521588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3005219635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99707484,0.0000703239,0.0014715727,0.0011417196,0.00015300923,0.000065583925,0.00000641766,0.0000031610164,0.000013354223],"genre_scores_gemma":[0.999073,0.0000767324,0.00028992284,0.0002187646,0.00030081044,0.0000017113096,0.0000074500076,0.000013229831,0.000018353689],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992117,0.000061848026,0.0002518172,0.00015497794,0.00015149535,0.00016814197],"domain_scores_gemma":[0.9996209,0.000013854973,0.0001396815,0.000099848694,0.000041715797,0.00008396952],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000076397846,0.000113266426,0.00016703828,0.000015525618,0.000056422963,0.00003103455,0.00021864728,0.0000617472,0.00003910605],"category_scores_gemma":[0.000071492614,0.0000709415,0.00015433678,0.000092568764,0.000037296737,0.000003842515,0.00010169275,0.00020368867,0.0000029225325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058648322,0.000056528672,0.0005517387,0.000011469026,0.000018779849,0.0000012254877,0.00010710256,0.00016074885,0.9979358,0.000019429968,0.00012098933,0.00095758063],"study_design_scores_gemma":[0.0003765427,0.00020111934,0.0023869383,0.000051771367,0.000008352656,0.0000034878808,0.00011372371,0.0020946395,0.9942278,0.000050119896,0.00039087725,0.00009457918],"about_ca_topic_score_codex":0.000004018235,"about_ca_topic_score_gemma":0.0000016906539,"teacher_disagreement_score":0.0037079102,"about_ca_system_score_codex":0.000012715643,"about_ca_system_score_gemma":0.00002864702,"threshold_uncertainty_score":0.28929105},"labels":[],"label_agreement":null},{"id":"W3006151491","doi":"10.1007/s00018-020-03471-5","title":"Beta-arrestins operate an on/off control switch for focal adhesion kinase activity","year":2020,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Fondation pour la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Autophosphorylation; Focal adhesion; Cell biology; Arrestin; G protein-coupled receptor; Proto-oncogene tyrosine-protein kinase Src; PTK2; Chemistry; Signal transduction; Phosphorylation; Biology; Protein kinase A; Mitogen-activated protein kinase kinase","score_opus":0.02828667251380597,"score_gpt":0.26691707762709327,"score_spread":0.2386304051132873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006151491","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9121717,0.0012258163,0.08505095,0.0009337225,0.0001294813,0.00033720728,0.000021378248,0.00001577935,0.000113969385],"genre_scores_gemma":[0.9954877,0.00006503791,0.0012703941,0.0028616663,0.00022067991,0.00002880482,0.000026971107,0.00001832639,0.000020431922],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855727,0.00011178332,0.00015475291,0.00066288654,0.00021089903,0.00030241744],"domain_scores_gemma":[0.9993206,0.000019404259,0.000064751745,0.00017499589,0.000060031558,0.00036020423],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003993872,0.00019479333,0.00020443204,0.000029640847,0.00032548798,0.000088793146,0.0002483462,0.000104132676,0.000019277923],"category_scores_gemma":[0.00015948282,0.00016170468,0.000115225834,0.000100489924,0.00014690521,0.000013835852,0.00005991921,0.00008324459,0.0000036386325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013673824,0.000047578473,0.00006523739,0.000013232629,0.000019577226,0.000008712741,0.00004413024,0.0009905082,0.9951884,0.00051170506,0.00012085758,0.002853295],"study_design_scores_gemma":[0.000796019,0.0021854355,0.000025543055,0.000008799063,0.000031844844,0.0000019964607,0.00010472941,0.016468031,0.9740085,0.00006879678,0.00605928,0.00024100808],"about_ca_topic_score_codex":0.000008707051,"about_ca_topic_score_gemma":0.0000026175096,"teacher_disagreement_score":0.08378056,"about_ca_system_score_codex":0.0000037043278,"about_ca_system_score_gemma":0.00011900767,"threshold_uncertainty_score":0.65941256},"labels":[],"label_agreement":null},{"id":"W3006585809","doi":"10.1126/scisignal.aax9520","title":"Dynamic interactions of the 5-HT <sub>6</sub> receptor with protein partners control dendritic tree morphogenesis","year":2020,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Agence Nationale de la Recherche","keywords":"Morphogenesis; Cell biology; Neurite; 5-HT receptor; Serotonin; Receptor; Biology; Branching (polymer chemistry); Chemistry; Neuroscience; Biochemistry","score_opus":0.00927128972488367,"score_gpt":0.2346142905371999,"score_spread":0.22534300081231623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006585809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97908586,0.00010313505,0.019794263,0.0004488053,0.00012799249,0.00033088707,0.000013757011,0.000012890999,0.000082423794],"genre_scores_gemma":[0.99794066,0.0000059141066,0.001639308,0.00026221835,0.00006595372,0.00003745349,0.0000048293177,0.00001769744,0.0000259437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99864954,0.000065940665,0.00022846009,0.00041694456,0.00034301225,0.00029612155],"domain_scores_gemma":[0.99928504,0.000015771906,0.00015097704,0.00024107445,0.00017448372,0.00013265865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031465752,0.00014600458,0.00015358345,0.00004266797,0.00026590485,0.000048583664,0.0004385399,0.000047858448,0.000033100932],"category_scores_gemma":[0.00016014029,0.00010214078,0.00010291009,0.00046938504,0.00033570497,0.000017527844,0.00007973095,0.00010870062,0.000006146596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057887155,0.000016639011,0.00013389162,0.000013140662,0.000020169045,7.220228e-7,0.00009539974,0.0021813947,0.9963705,0.000060269787,0.000015493775,0.001034475],"study_design_scores_gemma":[0.00033663108,0.0002064624,0.000059712744,0.00006296722,0.000023371585,0.000005137331,0.0003634211,0.0033131253,0.9952998,0.000024843768,0.00015937262,0.00014514795],"about_ca_topic_score_codex":0.000005955092,"about_ca_topic_score_gemma":0.00001595634,"teacher_disagreement_score":0.018854838,"about_ca_system_score_codex":0.000025204567,"about_ca_system_score_gemma":0.00026721606,"threshold_uncertainty_score":0.41651803},"labels":[],"label_agreement":null},{"id":"W3009588067","doi":"10.1101/2020.03.06.976563","title":"Targeting the water network in cyclin G associated kinase (GAK) with 4-anilino-quin(az)oline inhibitors","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; China Scholarship Council; Novartis Pharma; University of North Carolina at Chapel Hill; Biocenter Finland; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Ministry of Economic Development and Innovation; Pfizer","keywords":"Kinase; Potency; Drug discovery; Cyclin; Chemistry; Cyclin-dependent kinase; Biochemistry; In vitro; Gene; Cell cycle","score_opus":0.008336499095211456,"score_gpt":0.19968200046766765,"score_spread":0.1913455013724562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3009588067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99387884,0.0014572098,0.0016896852,0.00062064023,0.0012623852,0.00088645646,0.0000782472,0.00011947236,0.0000070573074],"genre_scores_gemma":[0.9943081,0.00031685265,0.0017574676,0.0006351741,0.0026113966,0.00014703326,0.000014290123,0.00019821983,0.000011439953],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9962195,0.00036125563,0.0007761538,0.0012823704,0.0004114864,0.0009492296],"domain_scores_gemma":[0.9981038,0.000035152043,0.00041356977,0.0008763933,0.00032875317,0.00024235457],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011823551,0.000714336,0.00064968696,0.00008080428,0.00024085844,0.00019906061,0.0006904023,0.0008635105,0.000052852498],"category_scores_gemma":[0.00021907211,0.00046111926,0.00021079938,0.00035695487,0.00011289409,0.000011074147,0.0008122412,0.0011192962,0.000024058441],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012327597,0.00008791195,0.0048467354,0.00007908958,0.00019309373,0.000063878724,0.000020387773,0.0046191067,0.9891651,0.00002969436,0.0007699372,0.000001756195],"study_design_scores_gemma":[0.0008337563,0.00019030203,0.0018295879,0.00034041778,0.00010001599,2.485556e-8,0.0000128533065,0.0011086145,0.9858926,0.0000064121737,0.008771054,0.00091436633],"about_ca_topic_score_codex":0.000069121044,"about_ca_topic_score_gemma":0.000024398674,"teacher_disagreement_score":0.008001117,"about_ca_system_score_codex":0.00010153003,"about_ca_system_score_gemma":0.00035432423,"threshold_uncertainty_score":0.99978405},"labels":[],"label_agreement":null},{"id":"W3009588214","doi":"10.7554/elife.52189.sa2","title":"Author response: Distinct inactive conformations of the dopamine D2 and D3 receptors correspond to different extents of inverse agonism","year":2020,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"","keywords":"Agonism; Dopamine receptor D3; Chemistry; Dopamine receptor D2; Dopamine; Neuroscience; Stereochemistry; Biology; Political science","score_opus":0.027456326066033782,"score_gpt":0.29669407893806043,"score_spread":0.26923775287202667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3009588214","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9371322,0.00802327,0.004934762,0.033962134,0.0058409455,0.0041870154,0.0033887478,0.000031760625,0.0024991557],"genre_scores_gemma":[0.5842313,0.002939889,0.0014133994,0.0036674584,0.00044026593,0.00023365543,0.0024629023,0.00014120684,0.40446994],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982699,0.00027601287,0.00058915775,0.0003598853,0.00032211753,0.00018288638],"domain_scores_gemma":[0.9985808,0.00007463963,0.00046194464,0.00045491618,0.00027413084,0.0001535721],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037124584,0.00031139396,0.0005848838,0.00006961701,0.00007567661,0.000014257508,0.00035864912,0.00024590697,0.0004404868],"category_scores_gemma":[0.0008900036,0.00020546364,0.00022097422,0.00015972744,0.000108738685,0.000003656422,0.0004633844,0.00020597705,0.000004486535],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00093329133,0.000082703715,0.00005170613,0.0012071503,0.00021421726,0.0000010214916,0.00028065286,0.0000063702646,0.47701076,0.00010605497,0.516293,0.0038130684],"study_design_scores_gemma":[0.00033552723,0.00057210313,0.00047938735,0.0009065655,0.00014681359,0.0000049159057,0.00022079753,0.00003305461,0.32171562,0.000018466873,0.67530066,0.0002660761],"about_ca_topic_score_codex":0.000045203036,"about_ca_topic_score_gemma":0.000050660223,"teacher_disagreement_score":0.40197077,"about_ca_system_score_codex":0.000029261757,"about_ca_system_score_gemma":0.00017352105,"threshold_uncertainty_score":0.8378564},"labels":[],"label_agreement":null},{"id":"W3010366691","doi":"10.1101/2020.03.02.973842","title":"Role of the C-terminal tail in regulating Proteinase Activated Receptor 2 (PAR2) signalling","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Arrestin; G protein-coupled receptor; Phosphorylation; Serine; Alanine; Palmitoylation; Cell biology; Biology; Receptor; Biochemistry; Chemistry; Signal transduction; Cysteine; Amino acid; Enzyme","score_opus":0.010860698550245275,"score_gpt":0.20732269610643114,"score_spread":0.19646199755618587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010366691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99718165,0.000711857,0.00061098963,0.00010402493,0.0003360824,0.00091850397,0.00008309621,0.00004513627,0.000008659527],"genre_scores_gemma":[0.99432766,0.00006312175,0.004798718,0.00007292484,0.00048005994,0.00013566094,0.000001589542,0.00011391917,0.0000063302923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99730533,0.00025498963,0.00068398006,0.0009501775,0.00035361954,0.00045192047],"domain_scores_gemma":[0.9979968,0.00001955849,0.00068104063,0.00087622023,0.0002717335,0.00015465895],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047692703,0.0004820589,0.000516153,0.00009917374,0.00011703152,0.00007527724,0.0007568754,0.0006491855,0.000056611498],"category_scores_gemma":[0.00031927758,0.0004416865,0.00025212922,0.0003720224,0.000095052004,0.00001038436,0.00080578873,0.00071482564,0.0000054284624],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010474291,0.000071378025,0.0012054306,0.00022301558,0.00007754829,0.0000057015386,0.000017201884,0.00047823132,0.99767196,0.000106218984,0.000030794334,0.000007788505],"study_design_scores_gemma":[0.00038766998,0.00008722131,0.0017937743,0.00061999995,0.000035547382,2.5348069e-8,0.0000146504,0.0005719475,0.9949556,0.00000773025,0.0010482732,0.0004775681],"about_ca_topic_score_codex":0.000058636935,"about_ca_topic_score_gemma":0.000004416556,"teacher_disagreement_score":0.0041877283,"about_ca_system_score_codex":0.00007070648,"about_ca_system_score_gemma":0.00056207017,"threshold_uncertainty_score":0.9998035},"labels":[],"label_agreement":null},{"id":"W3010845692","doi":"10.1016/j.bpj.2020.03.008","title":"Lipid-Protein Interactions Are a Unique Property and Defining Feature of G Protein-Coupled Receptors","year":2020,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":109,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"G protein-coupled receptor; Transmembrane domain; Transmembrane protein; Chemistry; Membrane lipids; Membrane protein; Receptor; Helix (gastropod); Biophysics; Biochemistry; Biology; Membrane","score_opus":0.013270628760874389,"score_gpt":0.23420899708949292,"score_spread":0.22093836832861852,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010845692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99276817,0.00013787825,0.00461906,0.0020819032,0.000101455895,0.00020158094,0.000007856437,0.000012762639,0.00006931248],"genre_scores_gemma":[0.9961873,0.000038229482,0.0029454692,0.00013011237,0.00040794088,0.000011975233,0.000008879664,0.000020157797,0.0002498837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923044,0.000082251,0.00018816048,0.00021327507,0.0001280018,0.00015786097],"domain_scores_gemma":[0.9994469,0.000006183868,0.0001918861,0.00009094592,0.00011446022,0.00014958411],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010281677,0.00013817396,0.00019235103,0.00002267277,0.00010635284,0.000044292912,0.000119930366,0.00010105497,0.000041752028],"category_scores_gemma":[0.00013070978,0.000092698276,0.00011534184,0.000091275295,0.000048409634,0.000009606957,0.00007904888,0.00030600838,0.000003629845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014780159,0.000041444724,0.000046910856,0.000027942942,0.000043014694,0.0000037471743,0.00008187799,0.0000074997497,0.9963282,0.00012758803,0.0003738637,0.002770163],"study_design_scores_gemma":[0.00034263014,0.00048778666,0.00003409927,0.00012563734,0.000014662476,0.000028617915,0.00023559024,0.00057158445,0.98814124,0.00006247007,0.009805196,0.00015051068],"about_ca_topic_score_codex":0.000005213863,"about_ca_topic_score_gemma":0.0000013180502,"teacher_disagreement_score":0.009431332,"about_ca_system_score_codex":0.000008849564,"about_ca_system_score_gemma":0.000054133758,"threshold_uncertainty_score":0.3780126},"labels":[],"label_agreement":null},{"id":"W3010864411","doi":"10.3791/60823","title":"Parallel Interrogation of &amp;#946;-Arrestin2 Recruitment for Ligand Screening on a GPCR-Wide Scale using PRESTO-Tango Assay","year":2020,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Computational biology; Drug discovery; Receptor; High-throughput screening; Biology; Bioinformatics; Signal transduction; Cell biology; Biochemistry","score_opus":0.14616100115735625,"score_gpt":0.4438315599611251,"score_spread":0.29767055880376886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3010864411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7266244,0.000738322,0.27204898,0.00008044223,0.00017593936,0.00029195423,0.0000062797767,0.0000036660163,0.000029976525],"genre_scores_gemma":[0.9025527,0.000054506563,0.09655696,0.00033351989,0.00037668258,0.000014252398,0.000024871402,0.00003417258,0.00005231846],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99866796,0.00010847933,0.0005731217,0.00020073766,0.00027124354,0.0001784775],"domain_scores_gemma":[0.99890924,0.000038513404,0.00061186077,0.00011970763,0.00017669942,0.00014397237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039033528,0.0001624873,0.00030869775,0.00005850166,0.00006465631,0.000028249828,0.00016960522,0.00010924407,0.000029965528],"category_scores_gemma":[0.00017127559,0.00014360478,0.0002722322,0.00006211691,0.000023931609,0.00001311924,0.00005517913,0.00008730485,9.049636e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001459531,0.000100714475,0.00022063682,0.000024283148,0.00016446873,0.0000014398175,0.0007552684,0.0017286068,0.99435186,0.000014965604,0.0004134502,0.0007647521],"study_design_scores_gemma":[0.0023287998,0.0014205773,0.00002588416,0.00020571491,0.000050239858,0.000007894886,0.0005724635,0.0014060435,0.98786664,0.000030271769,0.005944754,0.00014074052],"about_ca_topic_score_codex":0.000005679151,"about_ca_topic_score_gemma":9.3137504e-7,"teacher_disagreement_score":0.17592826,"about_ca_system_score_codex":0.00003421667,"about_ca_system_score_gemma":0.00007344927,"threshold_uncertainty_score":0.58560324},"labels":[],"label_agreement":null},{"id":"W3011984489","doi":"10.1124/dmd.119.089714","title":"Interaction of the Brain-Selective Sulfotransferase SULT4A1 with Other Cytosolic Sulfotransferases: Effects on Protein Expression and Function","year":2020,"lang":"en","type":"article","venue":"Drug Metabolism and Disposition","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; National Health and Medical Research Council; University of British Columbia","keywords":"Sulfotransferase; Immunoprecipitation; Dopamine; Cytosol; Biochemistry; Biology; HEK 293 cells; Cell biology; RNA interference; Sulfation; Enzyme; Gene; RNA; Endocrinology","score_opus":0.004836187711905856,"score_gpt":0.20209240497104658,"score_spread":0.19725621725914072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011984489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98849875,0.00039770515,0.010041646,0.00041729433,0.00006373016,0.00047703277,0.000023018189,0.000009763265,0.0000710767],"genre_scores_gemma":[0.9988405,0.000048144517,0.00009943397,0.00072335225,0.00017180841,0.00004383391,0.00003496803,0.000017683235,0.000020289446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921954,0.00014556469,0.00012474543,0.00028316665,0.00011972979,0.00010724452],"domain_scores_gemma":[0.99971443,0.0000206638,0.00005162611,0.00010266112,0.000044852903,0.00006575033],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000083213185,0.0001461241,0.00014219148,0.000024659475,0.00011153594,0.00002513075,0.00004534053,0.00006924973,0.000007261132],"category_scores_gemma":[0.000019854377,0.00009347254,0.00004748098,0.00008771751,0.00003942255,0.000018246481,0.000016039163,0.00009485013,4.9021634e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014685348,0.00003519813,0.00009418387,0.000069099275,0.000026254169,3.3956678e-7,0.00046649747,0.000038726423,0.99488443,0.00046631374,0.000041630723,0.0024087839],"study_design_scores_gemma":[0.0011454484,0.00041312477,0.0023015053,0.00011099679,0.00005296135,0.0000029086707,0.00013307406,0.0000401283,0.9945527,0.00008707845,0.0010384766,0.00012163939],"about_ca_topic_score_codex":0.00002904052,"about_ca_topic_score_gemma":0.00001061088,"teacher_disagreement_score":0.010341752,"about_ca_system_score_codex":0.000003281505,"about_ca_system_score_gemma":0.0000151390805,"threshold_uncertainty_score":0.38116995},"labels":[],"label_agreement":null},{"id":"W3012224900","doi":"10.1016/j.jaci.2020.03.004","title":"RGS4 promotes allergen- and aspirin-associated airway hyperresponsiveness by inhibiting PGE2 biosynthesis","year":2020,"lang":"en","type":"article","venue":"Journal of Allergy and Clinical Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"National Institute of Environmental Health Sciences; National Heart, Lung, and Blood Institute; U.S. Department of Health and Human Services; National Institutes of Health; National Center for Advancing Translational Sciences; Government of South Australia; National Institute of Allergy and Infectious Diseases; Division of Intramural Research, National Institute of Allergy and Infectious Diseases","keywords":"Bronchoconstriction; Medicine; Immunology; Aspirin; Respiratory epithelium; Bronchospasm; Asthma; Methacholine; Lung; Internal medicine; Respiratory disease","score_opus":0.019192870524945727,"score_gpt":0.27027881167073375,"score_spread":0.251085941145788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012224900","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9904578,0.0066833715,0.0004557647,0.002070258,0.00021202011,0.00005464174,0.0000060019343,0.0000060075563,0.000054172746],"genre_scores_gemma":[0.9898978,0.0085775005,0.0003998686,0.0007867759,0.00023373666,0.0000012382566,0.0000102036065,0.000019778017,0.00007312172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839973,0.00032914494,0.00069767603,0.00026337206,0.00009593659,0.00021415515],"domain_scores_gemma":[0.998996,0.00016662398,0.0004411026,0.00007984738,0.00015819746,0.0001582332],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006049672,0.00016072644,0.00041134417,0.000030497305,0.00010086185,0.000025186426,0.00015639333,0.00037812025,0.000075447104],"category_scores_gemma":[0.001095315,0.00013470325,0.00015888509,0.000057869336,0.00016589744,0.000010515236,0.00015180063,0.00031439235,0.0000021986887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007102689,0.0001346567,0.0007758343,0.0000062968556,0.0012300544,0.000019198586,0.00007547926,0.000003958949,0.9832686,0.000048182497,0.0005786067,0.013148825],"study_design_scores_gemma":[0.004420879,0.0097509995,0.0050719087,0.0001669001,0.00016082861,0.00020292142,0.0009674805,0.00019672871,0.91377735,0.00030565946,0.06435518,0.00062314916],"about_ca_topic_score_codex":0.0000050052795,"about_ca_topic_score_gemma":0.000008166326,"teacher_disagreement_score":0.069491275,"about_ca_system_score_codex":0.000005593074,"about_ca_system_score_gemma":0.000070275906,"threshold_uncertainty_score":0.54930395},"labels":[],"label_agreement":null},{"id":"W3012290332","doi":"10.1016/j.celrep.2020.02.095","title":"Nucleus Accumbens Cell Type- and Input-Specific Suppression of Unproductive Reward Seeking","year":2020,"lang":"en","type":"article","venue":"Cell Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Concordia University; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada Foundation for Innovation","keywords":"Nucleus accumbens; Neuroscience; Amygdala; Stimulation; Brain stimulation reward; Cell type; Psychology; Biology; Cell; Dopamine","score_opus":0.015175455147382309,"score_gpt":0.22421563417408216,"score_spread":0.20904017902669986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012290332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99420255,0.0017142646,0.000924735,0.000046700177,0.00030930547,0.00012866892,0.0000029697724,0.00001073561,0.00266008],"genre_scores_gemma":[0.9975974,0.0003953514,0.0013522317,0.0000710686,0.00022880234,0.0000018826664,0.00003713368,0.000022674676,0.00029345904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999065,0.000027084374,0.00024304556,0.00041410822,0.00011196707,0.00013881407],"domain_scores_gemma":[0.99935013,0.00000548379,0.00019050582,0.0002480693,0.00011166611,0.00009413709],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118385666,0.00011416761,0.0001513448,0.000015547648,0.000045685472,0.000014936588,0.000059965867,0.000106860745,0.000075318734],"category_scores_gemma":[0.0000490855,0.00010605057,0.00004428195,0.000082765,0.00003232904,0.0000039851107,0.00012344243,0.00007740393,0.000002281636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040260118,0.000022010661,0.0007914846,0.000044075026,0.00000720666,0.000039687362,0.00026840996,0.000045725646,0.9956119,0.000003834601,0.0026586736,0.00046674986],"study_design_scores_gemma":[0.00011367429,0.00017561503,0.00010911367,0.000012023367,0.000010035845,0.000021624344,0.00014679058,0.000023997636,0.94107914,0.000038666214,0.058153905,0.000115409886],"about_ca_topic_score_codex":0.0000047510644,"about_ca_topic_score_gemma":2.7600447e-7,"teacher_disagreement_score":0.055495232,"about_ca_system_score_codex":0.000004617037,"about_ca_system_score_gemma":0.000037962105,"threshold_uncertainty_score":0.43246168},"labels":[],"label_agreement":null},{"id":"W3012444143","doi":"10.1038/s41422-020-0303-z","title":"Hypercholesterolemia risk-associated GPR146 is an orphan G-protein coupled receptor that regulates blood cholesterol levels in humans and mice","year":2020,"lang":"en","type":"letter","venue":"Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"National Key Research and Development Program of China; Fundamental Research Funds for the Central Universities; Higher Education Discipline Innovation Project; State Key Laboratory of Natural Medicines; Wuhan University; Shanghai Jiao Tong University; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Orphan receptor; Cholesterol; Neuron-derived orphan receptor 1; Blood cholesterol; Medicine; Internal medicine; Endocrinology; Nuclear receptor; Biology; Genetics; Gene; Transcription factor","score_opus":0.06953252477391102,"score_gpt":0.30403964719868753,"score_spread":0.2345071224247765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3012444143","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809388,0.0011175867,0.00002741394,0.016353825,0.00011516103,0.0010139168,0.00024208524,0.00003175141,0.00015948236],"genre_scores_gemma":[0.94913566,0.0012794724,0.00045006478,0.037112698,0.0018974392,0.00021684308,0.0020447674,0.0003145046,0.007548533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99440426,0.0013459905,0.00051708065,0.0016461057,0.000922631,0.0011639538],"domain_scores_gemma":[0.99823254,0.0000955613,0.0002609348,0.0008262024,0.000296704,0.00028807102],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.001542172,0.0005799675,0.00063841237,0.00029445032,0.00033621636,0.00034409572,0.0009227257,0.0017951436,0.00040763002],"category_scores_gemma":[0.00018595367,0.0005830691,0.00016217188,0.00030854912,0.00025473104,0.000020217232,0.0005058775,0.0033174846,0.000059963546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007668363,0.00010807827,0.00057493674,0.00019529134,0.00009678816,0.00007804104,0.00047809593,0.0000030269841,0.9585261,7.619628e-7,0.03941729,0.0004449581],"study_design_scores_gemma":[0.0020312786,0.0011268965,0.0005274172,0.0002754559,0.000054773504,0.0000045065003,0.00024755212,0.00014576047,0.90723026,0.00018576707,0.087415285,0.00075506116],"about_ca_topic_score_codex":0.0005333317,"about_ca_topic_score_gemma":0.00017186326,"teacher_disagreement_score":0.051295802,"about_ca_system_score_codex":0.000082778955,"about_ca_system_score_gemma":0.00021662905,"threshold_uncertainty_score":0.9996621},"labels":[],"label_agreement":null},{"id":"W3013383869","doi":"10.1101/2020.03.22.002642","title":"Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"G protein-coupled receptor; Cannabinoid receptor; Cannabinoid; Receptor; Agonist; Intracellular; Neuroscience; Cell biology; Biology; Chemistry; Biophysics; Signal transduction; Biochemistry","score_opus":0.007137386963314889,"score_gpt":0.20258476518200655,"score_spread":0.19544737821869165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3013383869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9806521,0.0020884743,0.012701101,0.0011467119,0.0011999968,0.0008798776,0.0011647288,0.00016365615,0.0000033439994],"genre_scores_gemma":[0.9960102,0.0006359144,0.002217474,0.00025893244,0.00053991994,0.00012267723,0.00006180182,0.00014168635,0.00001140533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99665904,0.0002805419,0.0006312997,0.0014212847,0.00033325833,0.0006745927],"domain_scores_gemma":[0.99816716,0.000012896817,0.00031010888,0.00085894676,0.00033610617,0.00031480283],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043244197,0.0005930956,0.00051497086,0.00008917482,0.0001601848,0.00016265595,0.0005946699,0.0005477481,0.00008353571],"category_scores_gemma":[0.0005029817,0.0006948796,0.00016921137,0.0004117627,0.00009513929,0.000017876146,0.0006067846,0.00076163874,0.00003714485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007748149,0.000077812176,0.004111773,0.00012135426,0.00003277702,0.000014997013,0.000005572213,0.000037661117,0.9853941,0.000067839836,0.0100551685,0.000003452397],"study_design_scores_gemma":[0.0007098272,0.00006915175,0.0057136,0.00018549165,0.000042597563,3.2845914e-8,0.000005134055,0.00089335785,0.97456014,0.0000017169109,0.017037056,0.0007818969],"about_ca_topic_score_codex":0.00015954285,"about_ca_topic_score_gemma":0.0000054294983,"teacher_disagreement_score":0.015358078,"about_ca_system_score_codex":0.00021079536,"about_ca_system_score_gemma":0.000551412,"threshold_uncertainty_score":0.9995502},"labels":[],"label_agreement":null},{"id":"W3014116996","doi":"10.1093/cercor/bhaa094","title":"Corrigendum: Synaptic Mechanisms Underlying the Network State-Dependent Recruitment of VIP-Expressing Interneurons in the CA1 Hippocampus","year":2020,"lang":"en","type":"erratum","venue":"Cerebral Cortex","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Savoy Foundation","keywords":"Neuroscience; Hippocampus; Biology; Psychology","score_opus":0.05833719949724098,"score_gpt":0.28407162886357185,"score_spread":0.22573442936633087,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014116996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.43931141,0.058348905,0.1838233,0.0047070496,0.26142246,0.020644087,0.00081234466,0.00037749813,0.03055296],"genre_scores_gemma":[0.9871615,0.0008437197,0.0003792123,0.0014899867,0.00075671315,0.00018480753,0.0005615159,0.0001365176,0.008485985],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969224,0.0005193186,0.00069283525,0.0007630824,0.0004973529,0.00060502073],"domain_scores_gemma":[0.99845,0.00004829224,0.000541639,0.00078341854,0.00007571654,0.00010097608],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00059840834,0.0005034581,0.0005347378,0.000043255524,0.00021175141,0.00012802728,0.0011673548,0.00047413577,0.00011948011],"category_scores_gemma":[0.00006730229,0.00033203335,0.00030046457,0.00018712721,0.00010497666,0.0000068911036,0.0004417113,0.0011352196,0.000012487917],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003957571,0.00023951841,0.0001069641,0.00047117542,0.0010438351,0.00021876971,0.002475452,0.0012768093,0.6777526,0.002713814,0.29885352,0.014451758],"study_design_scores_gemma":[0.0073895357,0.012717828,0.005896112,0.006345278,0.0024519034,0.00079116237,0.020046014,0.019734873,0.107595295,0.09701323,0.7114656,0.008553154],"about_ca_topic_score_codex":0.0001196827,"about_ca_topic_score_gemma":0.00024026861,"teacher_disagreement_score":0.57015735,"about_ca_system_score_codex":0.00006517449,"about_ca_system_score_gemma":0.00029230054,"threshold_uncertainty_score":0.99991316},"labels":[],"label_agreement":null},{"id":"W3014619333","doi":"10.1038/s41467-020-15423-5","title":"GPR56/ADGRG1 is associated with response to antidepressant treatment","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University; St. Michael's Hospital; University of Toronto; University Health Network; McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Fondation de France; Government of Ontario; Agence Nationale de la Recherche; H. Lundbeck A/S; Government of Canada; National Alliance for Research on Schizophrenia and Depression; National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Ontario Brain Institute","keywords":"Antidepressant; Downregulation and upregulation; Norepinephrine; Depression (economics); Prefrontal cortex; Gene knockdown; Serotonin; Internal medicine; Endocrinology; Reuptake inhibitor; Medicine; Psychology; Pharmacology; Hippocampus; Neuroscience; Receptor; Chemistry; Dopamine; Apoptosis; Gene","score_opus":0.02301853030344028,"score_gpt":0.2898290879225338,"score_spread":0.26681055761909356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014619333","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97189623,0.0039938274,0.0010154325,0.021206776,0.00005904917,0.00043623784,0.00017044334,0.000052366726,0.0011696435],"genre_scores_gemma":[0.9924187,0.00026298725,0.0034391852,0.0033132564,0.000043075477,0.000037863585,0.00022532619,0.000019998499,0.00023962116],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99930537,0.00014411056,0.00011112347,0.0002123852,0.00009496798,0.00013206474],"domain_scores_gemma":[0.9988279,0.000047518442,0.000052553612,0.0008361328,0.00011664404,0.000119305085],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011371255,0.00011400456,0.0001163567,0.00002166681,0.00015657394,0.000025824185,0.00046148745,0.00018771777,0.00003963459],"category_scores_gemma":[0.0002137905,0.00009110902,0.000049816404,0.00015283222,0.000029151395,0.000002525429,0.00016473343,0.00017607845,0.000016820093],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040045823,0.00011502564,0.0009038512,0.0000012294109,0.0001385149,0.0000020634488,0.00044715696,0.000042935117,0.98906463,0.00018326157,0.007988742,0.00071214786],"study_design_scores_gemma":[0.0007342848,0.0012036972,0.0025165656,0.000022017422,0.000046223864,0.000003821602,0.00015294662,0.00022757833,0.43796074,0.0000117338,0.5568755,0.00024488327],"about_ca_topic_score_codex":0.0000095767355,"about_ca_topic_score_gemma":0.00006351848,"teacher_disagreement_score":0.5511039,"about_ca_system_score_codex":0.000022526276,"about_ca_system_score_gemma":0.000070733615,"threshold_uncertainty_score":0.37153178},"labels":[],"label_agreement":null},{"id":"W3015176539","doi":"10.17504/protocols.io.zfef3je","title":"Monitoring cell-surface expression of GPCR by ELISA v1","year":2019,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"G protein-coupled receptor; Receptor; Cell; Mutant; Cell surface receptor; Cell biology; Surface protein; Molecular biology; Biology; Chemistry; Computational biology; Biochemistry; Virology; Gene","score_opus":0.010535664824979267,"score_gpt":0.24445936006272306,"score_spread":0.23392369523774378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3015176539","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96561176,0.005950987,0.023093589,0.000011720111,0.0011191736,0.00024926392,0.0000430825,0.000014614034,0.003905818],"genre_scores_gemma":[0.983061,0.0010447812,0.009127158,0.000022005994,0.00023747297,0.000008403915,0.00015629081,0.00003971716,0.006303126],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987526,0.000046845882,0.0002917982,0.0005026591,0.00020007648,0.000205999],"domain_scores_gemma":[0.9990569,0.000009235952,0.00021269539,0.00056654296,0.00008842144,0.00006624844],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015499274,0.00024422244,0.00027352612,0.00001865892,0.000030283069,0.000025599804,0.00033464414,0.0005424248,0.00021306194],"category_scores_gemma":[0.000011079347,0.00021851592,0.00017097217,0.000022164488,0.000018558096,0.0000016011006,0.00068580225,0.00021574195,0.000014062574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020463405,0.00003814427,0.0006220468,0.00012611187,0.000018124672,2.5670738e-7,0.000028472075,0.0026999265,0.9896186,0.0000027886858,0.0066459756,0.00017906597],"study_design_scores_gemma":[0.00019307516,0.000071755756,0.000010624078,0.00013684684,0.0000136579465,3.6534652e-7,0.000101220394,0.00007344851,0.99416137,0.000038850387,0.0049531683,0.00024564215],"about_ca_topic_score_codex":0.000055219494,"about_ca_topic_score_gemma":2.4822097e-7,"teacher_disagreement_score":0.017449293,"about_ca_system_score_codex":0.00001209952,"about_ca_system_score_gemma":0.00006612166,"threshold_uncertainty_score":0.8910821},"labels":[],"label_agreement":null},{"id":"W3016277780","doi":"10.1096/fasebj.2020.34.s1.01952","title":"Extracellular interaction between Neurotrophic factor‐α1 and HTR1E serotonin receptor promotes cell survival","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Process Simulations Limited (Canada)","funders":"","keywords":"Cell biology; CREB; MAPK/ERK pathway; Receptor; Neurotrophic factors; HEK 293 cells; Biology; Signal transduction; Molecular biology; Chemistry; Transcription factor; Biochemistry","score_opus":0.03050900347400584,"score_gpt":0.24362374801916584,"score_spread":0.21311474454516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016277780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99203527,0.00090046757,0.005767869,0.00075005874,0.00029232242,0.00016763754,0.000014713266,0.000010468924,0.00006118086],"genre_scores_gemma":[0.99780303,0.00025792007,0.0003994519,0.00009920915,0.0011839096,0.00000344917,0.000020255644,0.00002724275,0.00020552837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989682,0.00020330327,0.00023040382,0.00022002927,0.00016592839,0.00021216845],"domain_scores_gemma":[0.9994539,0.0000226632,0.00015813926,0.00012713179,0.00005452751,0.00018361326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023834418,0.00015908429,0.0001520143,0.00002016823,0.0002204965,0.000117742726,0.00020158711,0.00009518102,0.00028008944],"category_scores_gemma":[0.00004971625,0.00011315202,0.000093446986,0.00005409733,0.00003723853,0.00001117865,0.000081927596,0.00038420522,0.000017981729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006119499,0.000011861553,0.0016214525,0.000011491998,0.00003124493,0.0000047063586,0.00020799943,0.000035271507,0.99623996,0.000007976845,0.00012999622,0.0016368325],"study_design_scores_gemma":[0.00035277012,0.00048107604,0.00027399528,0.000013124921,0.000023989573,0.00003345617,0.00022927589,0.00016844463,0.99236673,0.000036399928,0.005875987,0.0001447673],"about_ca_topic_score_codex":0.0000042334505,"about_ca_topic_score_gemma":6.51095e-7,"teacher_disagreement_score":0.0057677515,"about_ca_system_score_codex":0.000008714509,"about_ca_system_score_gemma":0.000036194288,"threshold_uncertainty_score":0.46142054},"labels":[],"label_agreement":null},{"id":"W3016420530","doi":"10.1101/2020.04.17.047217","title":"Discovery of <i>Plasmodium falciparum</i> SR12 as a GOLD-Domain seven transmembrane protein regulating GPCR trafficking in mammalian cells","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Alliance de recherche numérique du Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Thrombin; G protein-coupled receptor; Receptor; HEK 293 cells; Cell biology; Thrombin receptor; Biology; Plasmodium falciparum; Muscarinic acetylcholine receptor; Urokinase receptor; Signal transduction; Chemistry; Biochemistry; Platelet; Malaria; Immunology","score_opus":0.010098135714360239,"score_gpt":0.20838340401968464,"score_spread":0.1982852683053244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016420530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99161375,0.00085949036,0.0052051293,0.0002026748,0.00046504167,0.0013150789,0.00024195039,0.00007392788,0.000022974737],"genre_scores_gemma":[0.99037886,0.000086821514,0.008500804,0.00017979479,0.0004398005,0.00018013857,0.0000041763456,0.00020643012,0.000023163642],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99594176,0.00030143355,0.0010604236,0.0014768388,0.0004737113,0.00074586185],"domain_scores_gemma":[0.997894,0.00002400341,0.0006548725,0.0010188124,0.00017569381,0.00023265739],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00072324363,0.0007673102,0.0009334136,0.00020090581,0.00008088268,0.00016507399,0.0007848324,0.0009429571,0.000023897079],"category_scores_gemma":[0.00009705922,0.0008594787,0.00039980572,0.0004108397,0.00011141827,0.000028080472,0.0004386311,0.0007579511,0.000008353849],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022192877,0.00013707334,0.00013402106,0.000873277,0.0001263195,0.000049982864,0.00006251327,0.0014586897,0.99648947,0.0003871566,0.00005441928,0.000005132079],"study_design_scores_gemma":[0.0009871467,0.00021369748,0.00029779342,0.0008491658,0.00005876612,6.616682e-8,0.000033806806,0.00033206522,0.9949693,0.000014634518,0.0013429944,0.00090056274],"about_ca_topic_score_codex":0.000109923465,"about_ca_topic_score_gemma":0.000018860559,"teacher_disagreement_score":0.0032956752,"about_ca_system_score_codex":0.0000857456,"about_ca_system_score_gemma":0.00068781397,"threshold_uncertainty_score":0.9993856},"labels":[],"label_agreement":null},{"id":"W3016439079","doi":"10.3390/molecules25081872","title":"Synthesis and Evaluation of [18F]FEtLos and [18F]AMBF3Los as Novel 18F-Labelled Losartan Derivatives for Molecular Imaging of Angiotensin II Type 1 Receptors","year":2020,"lang":"en","type":"article","venue":"Molecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Graduate Education; Fundação de Amparo à Pesquisa do Estado de São Paulo; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Government of Canada","keywords":"Losartan; Biodistribution; Chemistry; Losartan Potassium; Angiotensin II; In vivo; Angiotensin receptor; Receptor; Renin–angiotensin system; Pharmacology; Positron emission tomography; In vitro; Internal medicine; Biochemistry; Medicine; Nuclear medicine; Biology","score_opus":0.023390898739741945,"score_gpt":0.26932266191386817,"score_spread":0.2459317631741262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016439079","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868612,0.0025622651,0.009529195,0.00042898272,0.000044727465,0.00042943688,0.000030461115,0.0000078290195,0.00010585166],"genre_scores_gemma":[0.98850745,0.00011477686,0.011009931,0.00022102312,0.000039066304,0.000022688471,0.000039562,0.00003355579,0.000011936397],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988652,0.00008340826,0.00028296505,0.00037969975,0.00021993175,0.00016880558],"domain_scores_gemma":[0.99917245,0.000040609244,0.00017689551,0.00014324217,0.0003810699,0.00008574756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030776532,0.00018345905,0.00027713145,0.0000510321,0.00007827035,0.000014672486,0.00009654145,0.00006512787,0.000032773278],"category_scores_gemma":[0.0006043951,0.00018055555,0.0000801906,0.00011084542,0.000106669395,0.000007816724,0.00011424879,0.00004500251,4.0596706e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024425855,0.0000423661,0.00017336666,0.000060938157,0.00011555862,9.957516e-7,0.00019805029,0.00010473416,0.99582714,0.00034050603,0.00010854482,0.0027835714],"study_design_scores_gemma":[0.00075044273,0.000558778,0.00009739996,0.00006046096,0.00015759438,0.0000057888515,0.00033627765,0.005610606,0.99149215,0.00029109223,0.00044968427,0.00018971456],"about_ca_topic_score_codex":0.000020470408,"about_ca_topic_score_gemma":0.000002192273,"teacher_disagreement_score":0.005505872,"about_ca_system_score_codex":0.000006654073,"about_ca_system_score_gemma":0.00007187467,"threshold_uncertainty_score":0.7362842},"labels":[],"label_agreement":null},{"id":"W3016692868","doi":"10.1038/s41467-020-15945-y","title":"Author Correction: Exploring use of unsupervised clustering to associate signaling profiles of GPCR ligands to clinical response","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Réseau québécois de recherche sur la douleur","keywords":"G protein-coupled receptor; Computational biology; Cluster analysis; Computer science; Bioinformatics; Data science; Biology; Signal transduction; Artificial intelligence; Cell biology","score_opus":0.15267439253481796,"score_gpt":0.3631937604254114,"score_spread":0.21051936789059345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016692868","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98844093,0.0004608931,0.0064948737,0.0037395507,0.00044826407,0.00031282377,0.000055983583,0.000023229142,0.000023465522],"genre_scores_gemma":[0.9727232,0.00009627772,0.026151983,0.00069492485,0.00013355928,0.000044318276,0.000047301804,0.000023403429,0.00008503939],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987083,0.00026652214,0.00049522636,0.00024163329,0.00014742413,0.0001409118],"domain_scores_gemma":[0.9983168,0.00027789795,0.00015520044,0.00075952936,0.00032933045,0.00016122202],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007081146,0.000116946736,0.0002455409,0.00006216737,0.00011273032,0.000022058151,0.00056749507,0.0002574528,0.000015283442],"category_scores_gemma":[0.0023466062,0.00012079091,0.0001304921,0.00031514422,0.00003260018,0.000010714141,0.0005457201,0.0003665384,0.0000034910959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054272957,0.000059549056,0.001527018,0.000011754691,0.00005844123,2.6617556e-7,0.00067613955,0.001158605,0.99249274,0.000041706342,0.0016852755,0.0017457515],"study_design_scores_gemma":[0.00025783858,0.00059253233,0.0025386943,0.00009844278,0.00003083135,9.937386e-7,0.0004629722,0.0015569866,0.9544889,0.000003675291,0.039793838,0.00017432081],"about_ca_topic_score_codex":0.000010616717,"about_ca_topic_score_gemma":0.000027723238,"teacher_disagreement_score":0.03810856,"about_ca_system_score_codex":0.000014113297,"about_ca_system_score_gemma":0.000077647506,"threshold_uncertainty_score":0.49257103},"labels":[],"label_agreement":null},{"id":"W3016887434","doi":"10.1101/lm.051177.119","title":"Learning-induced mRNA alterations in olfactory bulb mitral cells in neonatal rats","year":2020,"lang":"en","type":"article","venue":"Learning & Memory","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; Olfactory bulb; Odor; Neuroscience; Messenger RNA; Cell biology; CREB; Transcription factor; Psychology; Genetics; Gene; Central nervous system","score_opus":0.01823878140589491,"score_gpt":0.2334796177841824,"score_spread":0.2152408363782875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016887434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99787664,0.0003163521,0.0008265481,0.0002080685,0.00019331141,0.00014173845,0.0000016685332,0.000028167282,0.00040749327],"genre_scores_gemma":[0.99824613,0.000046655856,0.00034158022,0.00030256584,0.000292086,0.000014018969,0.000076395634,0.000034435867,0.0006461292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863374,0.00022798138,0.00026595464,0.00041791887,0.00013788503,0.00031654496],"domain_scores_gemma":[0.9996334,0.00002384521,0.00008231494,0.00011872378,0.000025695319,0.0001160776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022644101,0.00017521938,0.00019081157,0.00006864794,0.000091079535,0.00003940005,0.00015758423,0.0001610977,0.00020214217],"category_scores_gemma":[0.00015506096,0.00019278619,0.0001068313,0.00014474026,0.000021616765,0.000009944755,0.00007863889,0.00063020375,0.000049460756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057414203,0.000016504933,0.0019950077,0.000013229977,0.0000118073785,0.00002880046,0.0016386942,0.024013884,0.96872133,0.000009472687,0.000059849233,0.0034340206],"study_design_scores_gemma":[0.0007102934,0.00039041438,0.0010145105,0.000029957482,0.0000063547363,0.0000041407498,0.0011171409,0.0034543118,0.9869068,0.000007869751,0.0060696495,0.00028851727],"about_ca_topic_score_codex":0.000067923786,"about_ca_topic_score_gemma":0.00004557023,"teacher_disagreement_score":0.020559572,"about_ca_system_score_codex":0.000023116603,"about_ca_system_score_gemma":0.00007190529,"threshold_uncertainty_score":0.7861593},"labels":[],"label_agreement":null},{"id":"W3016991223","doi":"10.1096/fasebj.2020.34.s1.04515","title":"Loss‐ And Gain of Function Mutations in the Type 1 IP3 Receptor (IP3R1) Modify Agonist‐Evoked Vasoactive Responses in Cerebral and Skeletal Muscle Resistance Arteries From Adult Mice","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Vasoconstriction; Endocrinology; Agonist; Internal medicine; Transient receptor potential channel; Wild type; Biology; Receptor; Mutant; Chemistry; Medicine; Biochemistry","score_opus":0.013803964374089497,"score_gpt":0.23013051500795523,"score_spread":0.21632655063386574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016991223","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971024,0.0007632894,0.0007903499,0.0010871567,0.00006726758,0.00009463734,0.000043121327,0.0000019606457,0.000049823095],"genre_scores_gemma":[0.99883986,0.00027932422,0.00042378512,0.00024610627,0.00013415806,0.000004007486,0.000024884861,0.000008077416,0.000039795075],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916357,0.0002858709,0.000191415,0.00014455439,0.000101782796,0.00011282455],"domain_scores_gemma":[0.9996323,0.00007597978,0.000110092704,0.00008407595,0.000058419428,0.00003915322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027481045,0.000089226785,0.00010844802,0.000024910736,0.00011462435,0.000044170734,0.00010103054,0.00006170825,0.000034245546],"category_scores_gemma":[0.00011675215,0.000060027127,0.000032957287,0.00008799524,0.000104379644,0.000012702235,0.000028358478,0.00019134961,8.7438167e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00085135346,0.000018685476,0.00089784607,0.00000661302,0.00002974577,0.000004134564,0.0025087907,0.000061390936,0.99495065,0.00012243014,0.00008655272,0.00046182735],"study_design_scores_gemma":[0.0029922638,0.0012933296,0.05702659,0.00014505823,0.00011681295,0.00004876287,0.023989191,0.00094326533,0.9061486,0.0049702567,0.0019335834,0.00039225086],"about_ca_topic_score_codex":0.00004240013,"about_ca_topic_score_gemma":0.00013578926,"teacher_disagreement_score":0.088801995,"about_ca_system_score_codex":0.000008698031,"about_ca_system_score_gemma":0.000047913505,"threshold_uncertainty_score":0.24478352},"labels":[],"label_agreement":null},{"id":"W3017190007","doi":"10.17863/cam.48506","title":"Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics","year":2019,"lang":"en","type":"article","venue":"Apollo (University of Cambridge)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Canadian Institutes of Health Research; National Institute of Diabetes and Digestive and Kidney Diseases; School of Medicine, Indiana University; National Institutes of Health; Michael Smith Health Research BC; Manpei Suzuki Diabetes Foundation; European Commission; University of Oxford; Deutsche Forschungsgemeinschaft; Human Islet Research Network; University of Alberta; Diabetes UK; Wellcome Trust","keywords":"Fluorescence; Fluorescence microscope; Microscopy; Biophysics; Chemistry; Distribution (mathematics); Dynamics (music); Biological system; Biology; Optics; Physics; Mathematics; Acoustics; Mathematical analysis","score_opus":0.007007943159387442,"score_gpt":0.18646644982269028,"score_spread":0.17945850666330285,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017190007","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98771536,0.00032439112,0.010812056,0.000091916765,0.00022196403,0.00029945548,0.00025770455,0.000014339493,0.00026281597],"genre_scores_gemma":[0.99440134,0.00028822783,0.0020929307,0.00002494926,0.000041201347,4.4146464e-7,0.0012579281,0.000013301532,0.0018796603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991296,0.000052934967,0.00012239096,0.00032373724,0.00013673266,0.00023464022],"domain_scores_gemma":[0.99946743,0.0000090150015,0.0001039723,0.00022646399,0.0001052866,0.00008781206],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013680455,0.0001423381,0.00019975826,0.000037257225,0.00015512631,0.000015915424,0.00015872886,0.00014256283,0.00004201539],"category_scores_gemma":[0.000009037547,0.00017106485,0.000096412834,0.00008272131,0.0000939908,0.000015190331,0.00013620139,0.00008290592,0.00002054363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017245961,0.000059811122,0.0036073574,0.0000637773,0.000039656945,0.0000016089092,0.000107748674,0.00003756731,0.99188465,0.0005184274,0.0028549759,0.00065197446],"study_design_scores_gemma":[0.0023688662,0.0011709176,0.004753653,0.00012932235,0.000094735544,0.000039413804,0.002964773,0.0041227085,0.95627,0.000020378176,0.027462391,0.00060289004],"about_ca_topic_score_codex":0.00057929143,"about_ca_topic_score_gemma":0.0000700827,"teacher_disagreement_score":0.035614684,"about_ca_system_score_codex":0.00006735606,"about_ca_system_score_gemma":0.00006392658,"threshold_uncertainty_score":0.69758224},"labels":[],"label_agreement":null},{"id":"W3019027684","doi":"10.1016/j.cellsig.2020.109641","title":"GGA3 interacts with L-type prostaglandin D synthase and regulates the recycling and signaling of the DP1 receptor for prostaglandin D2 in a Rab4-dependent mechanism","year":2020,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Prostaglandin D2; Cell biology; Agonist; Receptor; G protein-coupled receptor; Chemistry; Colocalization; Prostaglandin E2 receptor; Immunoprecipitation; Signal transduction; Biology; Biochemistry","score_opus":0.014227821980967054,"score_gpt":0.21442584117682037,"score_spread":0.2001980191958533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3019027684","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9823616,0.001666529,0.014460098,0.0003463851,0.00011216804,0.0010143274,0.000015870317,0.000010524967,0.000012490963],"genre_scores_gemma":[0.99710727,0.00014714913,0.0022192642,0.00015889587,0.00016168981,0.000045981407,0.00003571916,0.00004593206,0.00007809285],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851906,0.00012505961,0.00038065496,0.00049427385,0.00018763315,0.00029333946],"domain_scores_gemma":[0.9992601,0.00010592763,0.00023387943,0.00020135684,0.00010038094,0.00009835583],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066424947,0.00024177654,0.000281676,0.000038807717,0.00018867437,0.000077685145,0.00021968585,0.00014574316,0.000018720526],"category_scores_gemma":[0.00018037904,0.00014865022,0.00007140753,0.00015119888,0.00008359657,0.000012887169,0.00014792033,0.00020447622,4.0483675e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005633719,0.000023342072,0.00048803253,0.00013808036,0.000055673907,0.0000029221032,0.0011854733,0.0006814681,0.99624354,0.00021700971,0.00001034002,0.0003907403],"study_design_scores_gemma":[0.0010146429,0.0005577715,0.000010216171,0.0002895914,0.00004737501,0.0000075694675,0.000998332,0.004456136,0.991676,0.00040172896,0.00032125728,0.00021940802],"about_ca_topic_score_codex":0.000017199405,"about_ca_topic_score_gemma":0.000014857719,"teacher_disagreement_score":0.014745669,"about_ca_system_score_codex":0.000012955349,"about_ca_system_score_gemma":0.000064417494,"threshold_uncertainty_score":0.606178},"labels":[],"label_agreement":null},{"id":"W30206338","doi":"10.1038/s41366-018-0202-2","title":"Угрозы национальной безопасности Российской Федерации на Южном Кавказе","year":2008,"lang":"ru","type":"article","venue":"Ученые записки Казанского университета. Серия Гуманитарные науки","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Business","score_opus":0.015596865826031859,"score_gpt":0.22410395714178796,"score_spread":0.2085070913157561,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W30206338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8492266,0.054567643,0.012172544,0.0024933121,0.013585624,0.004416149,0.0018550088,0.0009562774,0.060726833],"genre_scores_gemma":[0.93233,0.015627941,0.004500071,0.002799879,0.007766946,0.00033914924,0.0021432021,0.0009331056,0.033559684],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9834671,0.0010544793,0.0034447517,0.004826621,0.0025086848,0.0046983827],"domain_scores_gemma":[0.99005896,0.00029830952,0.0016823295,0.004478436,0.0012239784,0.0022579597],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"category_scores_codex":[0.0018384589,0.0033671353,0.0029195442,0.0008699509,0.0025287387,0.00058078236,0.0033506027,0.0033815424,0.011868738],"category_scores_gemma":[0.0007974068,0.0035682914,0.0022451147,0.0018443252,0.0014774015,0.00018724034,0.0018661229,0.0023815506,0.0034341475],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019380555,0.002859414,0.0037956869,0.0009026801,0.0033129405,0.0017794126,0.002739142,0.0016811279,0.7651198,0.0032379443,0.1687681,0.043865707],"study_design_scores_gemma":[0.005592405,0.0027659654,0.001562562,0.00056188356,0.0007325297,0.00139675,0.0010702268,0.00092930684,0.4190048,0.0008915274,0.56050426,0.0049878177],"about_ca_topic_score_codex":0.00053113024,"about_ca_topic_score_gemma":0.0002232734,"teacher_disagreement_score":0.39173615,"about_ca_system_score_codex":0.00048760037,"about_ca_system_score_gemma":0.0021041408,"threshold_uncertainty_score":0.99992},"labels":[],"label_agreement":null},{"id":"W3020939423","doi":"10.1007/978-1-4939-6581-6_12","title":"Measuring Phagosomal pH by Fluorescence Microscopy","year":2016,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; St. Michael's Hospital; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Photobleaching; Microscopy; Fluorescence; Fluorescence microscope; Instrumentation (computer programming); Fluorescence-lifetime imaging microscopy; Population; Calibration; Materials science; Nanotechnology; Biophysics; Chemistry; Optics; Computer science; Physics; Biology; Medicine","score_opus":0.020773903258204728,"score_gpt":0.34781132998117414,"score_spread":0.3270374267229694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020939423","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15850046,0.0017663809,0.8388525,0.0001334004,0.00030907776,0.00013982615,0.000014850946,0.000015936015,0.0002675204],"genre_scores_gemma":[0.17187205,0.0004701273,0.82676667,0.00034695494,0.000121842255,0.00005718178,0.00003260949,0.000051212603,0.00028134816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99773055,0.00075596204,0.00031438013,0.0006367856,0.00007739842,0.00048493425],"domain_scores_gemma":[0.9993099,0.000049373244,0.00008845022,0.00040857235,0.000052373438,0.000091333124],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00094240386,0.00022996393,0.0002574308,0.00007603407,0.000049440845,0.000013360211,0.0003682537,0.00032435387,0.0001042704],"category_scores_gemma":[0.00036625972,0.00017324594,0.00011759288,0.00011430496,0.00013647377,0.0000034700365,0.00017430006,0.000110398694,0.000012176368],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004575472,0.000031617157,0.0008755739,0.000005189791,0.000024701882,0.0000055678915,0.000010230747,0.0000018352472,0.9687176,0.0006103486,0.00013213546,0.029539457],"study_design_scores_gemma":[0.0006221061,0.00019962952,0.000026106109,0.000024753359,0.000006440883,0.000012918346,0.0000100338475,0.000011319407,0.98434734,0.0020892534,0.012391402,0.00025868294],"about_ca_topic_score_codex":0.00001734061,"about_ca_topic_score_gemma":0.0000025843121,"teacher_disagreement_score":0.029280774,"about_ca_system_score_codex":0.0000275015,"about_ca_system_score_gemma":0.000044924418,"threshold_uncertainty_score":0.70647645},"labels":[],"label_agreement":null},{"id":"W3021287898","doi":"10.1016/b978-0-12-369497-3.10030-5","title":"Prefrontal Cortex","year":2011,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Neuroscience; Prefrontal cortex; Cognitive flexibility; Nissl body; Psychology; Working memory; Flexibility (engineering); Biology; Cognition","score_opus":0.01316470994735735,"score_gpt":0.21542676377778355,"score_spread":0.2022620538304262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3021287898","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00050429546,0.0016368313,0.00005667844,0.0000028158743,0.0004944107,0.0002833756,0.00003686011,0.000021231574,0.9969635],"genre_scores_gemma":[0.007027286,0.00023716739,0.00043925195,0.00019238076,0.0007033045,0.000019833975,0.0001640844,0.00011420359,0.9911025],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987818,0.0000135257405,0.0002830013,0.0005149435,0.00015903766,0.00024767645],"domain_scores_gemma":[0.99913466,0.0000029494934,0.00016938812,0.0005054567,0.00006694272,0.00012058031],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000105288564,0.00036515488,0.0003051044,0.000043194577,0.00007010996,0.000020522286,0.0002682742,0.00055844267,0.0013997885],"category_scores_gemma":[0.000005094452,0.00034620293,0.000280214,0.000002589366,0.00007336456,0.0000010495019,0.0001651776,0.00022241457,0.00019336455],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037022743,0.000006649062,0.00000127135,0.000025054474,0.0001505981,0.00001299097,0.00004243418,8.039607e-8,0.102538906,0.0035320837,0.00036332136,0.89328957],"study_design_scores_gemma":[0.0001743925,0.00022425369,0.0000068204167,0.000078428864,0.00006260404,0.000021677992,0.0000028716438,6.7003964e-7,0.02308915,0.0050110775,0.9709027,0.00042537355],"about_ca_topic_score_codex":5.440156e-7,"about_ca_topic_score_gemma":0.000013725128,"teacher_disagreement_score":0.97053933,"about_ca_system_score_codex":0.000017049171,"about_ca_system_score_gemma":0.00009048463,"threshold_uncertainty_score":0.99989897},"labels":[],"label_agreement":null},{"id":"W3022510125","doi":"10.1093/noajnl/vdaa053","title":"Expression profiling of the adhesion G protein-coupled receptor GPR133 (ADGRD1) in glioma subtypes","year":2020,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute; National Institutes of Health; Friedberg Charitable Foundation; Deutsche Forschungsgemeinschaft; National Institute of Neurological Disorders and Stroke; New York State Stem Cell Science","keywords":"Glioma; Isocitrate dehydrogenase; Biology; Malignancy; Immunohistochemistry; IDH1; Cancer research; Brain tumor; Pathology; Mutant; Medicine; Gene; Enzyme","score_opus":0.01254065024205513,"score_gpt":0.2568209050475636,"score_spread":0.24428025480550847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3022510125","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996656,0.0012406282,0.0004862917,0.0005689284,0.0003447918,0.00052127364,0.0000058209475,0.000014270859,0.00016199925],"genre_scores_gemma":[0.9958521,0.00016394087,0.0032889056,0.00036596842,0.00021051521,0.00006710731,0.000011705557,0.000021568832,0.00001815764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869573,0.00020821285,0.00032028535,0.00040645053,0.00014709968,0.00022223484],"domain_scores_gemma":[0.99938846,0.00004520166,0.00022773378,0.0002134299,0.00006280594,0.00006236975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017057951,0.0001559149,0.00023536875,0.00003072839,0.000078685,0.0000065309746,0.0003127238,0.00019045097,0.00007495203],"category_scores_gemma":[0.00042215633,0.00011177234,0.000091806796,0.00018525834,0.00008734067,0.000012318053,0.00017457485,0.0001889909,0.0000057724533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003792921,0.000048080314,0.0017575442,0.00004317403,0.000004673779,0.0000041852636,0.000086105705,0.00022924085,0.9959554,0.000056223886,0.00007283041,0.001363244],"study_design_scores_gemma":[0.00056833756,0.0007067437,0.000090760004,0.00003967741,0.000005146437,0.0000037591717,0.00015577425,0.0001615216,0.9846103,0.00010455244,0.013436126,0.00011727954],"about_ca_topic_score_codex":0.000003256926,"about_ca_topic_score_gemma":0.000008596559,"teacher_disagreement_score":0.013363295,"about_ca_system_score_codex":0.000012330136,"about_ca_system_score_gemma":0.000096221636,"threshold_uncertainty_score":0.45579436},"labels":[],"label_agreement":null},{"id":"W3023319216","doi":"10.1523/eneuro.0433-19.2020","title":"Targeting Morphine-Responsive Neurons: Generation of a Knock-In Mouse Line Expressing Cre Recombinase from the Mu-Opioid Receptor Gene Locus","year":2020,"lang":"en","type":"article","venue":"eNeuro","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Douglas Mental Health University Institute","funders":"National Institute on Alcohol Abuse and Alcoholism; National Institutes of Health; Wallonie-Bruxelles International; National Institute on Drug Abuse; Canada Research Chairs","keywords":"Gene knockin; Cre recombinase; Locus (genetics); Morphine; Opioid receptor; Opioid; Gene knockout; Knockout mouse; Receptor; Gene; Biology; Molecular biology; Transgene; Genetically modified mouse; Genetics; Pharmacology","score_opus":0.026777088896230865,"score_gpt":0.23676440732811976,"score_spread":0.2099873184318889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3023319216","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923226,0.0014099509,0.0049339896,0.0007425309,0.00026645142,0.00021421502,0.00008016495,0.000015739388,0.000014347861],"genre_scores_gemma":[0.99392927,0.00038958917,0.0030750993,0.0013309513,0.00083181175,0.000020236323,0.00029475612,0.00004390799,0.00008440881],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858546,0.0002649771,0.00036317031,0.000437483,0.00014657853,0.00020233355],"domain_scores_gemma":[0.9993399,0.00006618266,0.00016739467,0.00027119892,0.00007442078,0.00008093785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016679922,0.00018201776,0.00019208582,0.000024631356,0.00008888942,0.00003438303,0.00023777783,0.000108675,0.00012228145],"category_scores_gemma":[0.0006576157,0.00015236327,0.000091068905,0.00011006993,0.00003221285,0.000008737639,0.00013926534,0.00017139259,0.0000067836327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000136863,0.000035174202,0.00012233309,0.0000066465013,0.000013099281,0.000008474439,0.00029804843,0.0044360314,0.99219406,0.0000063147936,0.0018408574,0.0009020958],"study_design_scores_gemma":[0.00049703196,0.00024681093,0.000022891469,0.00001406297,0.000009575191,0.0000013502187,0.00011302517,0.0053794975,0.988901,0.00001803623,0.004644857,0.00015184106],"about_ca_topic_score_codex":0.00006476283,"about_ca_topic_score_gemma":0.000008182653,"teacher_disagreement_score":0.0032930411,"about_ca_system_score_codex":0.000008056968,"about_ca_system_score_gemma":0.000055428765,"threshold_uncertainty_score":0.6213194},"labels":[],"label_agreement":null},{"id":"W3023333636","doi":"10.1021/jacs.6b04032","title":"Single-Molecule Analysis of the Supramolecular Organization of the M<sub>2</sub> Muscarinic Receptor and the Gα<sub>i1</sub> Protein","year":2016,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada; Government of Canada","keywords":"Mastoparan; Chemistry; Random hexamer; Tetramer; G protein; Förster resonance energy transfer; Heterotrimeric G protein; G protein-coupled receptor; Biophysics; Photobleaching; Histone octamer; Green fluorescent protein; Muscarinic acetylcholine receptor; Receptor; Biochemistry; Biology; Fluorescence; Chromatin","score_opus":0.00417661368959488,"score_gpt":0.19519210958427957,"score_spread":0.1910154958946847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3023333636","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99560314,0.00017577941,0.001983004,0.001926618,0.00008273301,0.00020367811,0.000013512767,0.0000025944405,0.00000891149],"genre_scores_gemma":[0.99887073,0.00023131983,0.00022544632,0.00051109114,0.00011851673,0.0000037645036,0.0000021701749,0.000024838178,0.000012107273],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834794,0.00029695855,0.0005156433,0.00020850294,0.0004284379,0.00020251867],"domain_scores_gemma":[0.99769676,0.00007729784,0.0013103901,0.00050910725,0.0003467658,0.000059702656],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055987673,0.00017601556,0.0004161158,0.000017433425,0.0001316,0.000021474794,0.0007088554,0.000115012015,0.000010341773],"category_scores_gemma":[0.0005772249,0.00007071997,0.0009714653,0.000828236,0.0009055352,0.000008204969,0.0003882386,0.00022363703,2.7060645e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006242357,0.000057327925,0.00079611334,0.000009095452,0.0006985111,8.278538e-8,0.00014131036,0.00002449172,0.9964656,0.00003075269,0.00034721717,0.0013670345],"study_design_scores_gemma":[0.00057554076,0.00008167389,0.0006932337,0.00005805008,0.0005015442,0.000007670999,0.00016921913,0.00004544767,0.99751174,0.00008064189,0.00016993532,0.00010531699],"about_ca_topic_score_codex":0.000012731247,"about_ca_topic_score_gemma":0.0000018697779,"teacher_disagreement_score":0.0032675772,"about_ca_system_score_codex":0.000052172923,"about_ca_system_score_gemma":0.000115191564,"threshold_uncertainty_score":0.3336482},"labels":[],"label_agreement":null},{"id":"W3024275141","doi":"10.3389/fnmol.2020.00067","title":"D1 Dopamine Receptor Activation Induces Neuronal eEF2 Pathway-Dependent Protein Synthesis","year":2020,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministry of Health, State of Israel; Azrieli Foundation; Israel Science Foundation; International Development Research Centre; Canadian Institutes of Health Research; EU Joint Programme – Neurodegenerative Disease Research","keywords":"Dopamine; Dopamine receptor D1; Dopamine receptor; Dopamine receptor D3; Biology; Neuroscience; Dephosphorylation; Dopamine receptor D2; Cell biology; Translation (biology); Dopaminergic; Phosphorylation; Messenger RNA; Phosphatase; Genetics; Gene","score_opus":0.01306243323811387,"score_gpt":0.21317840298650584,"score_spread":0.20011596974839196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3024275141","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8740132,0.000087262924,0.12427396,0.000599221,0.0004781616,0.0003594409,0.000018343646,0.0000250032,0.00014543257],"genre_scores_gemma":[0.9906915,0.000035209672,0.00745846,0.001499312,0.00011255813,0.00007485388,0.000021880178,0.000034722776,0.000071522336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980082,0.00016838333,0.000267888,0.0007883226,0.00040189837,0.00036529827],"domain_scores_gemma":[0.9994063,0.0000064721175,0.000121288926,0.00026084122,0.000037891692,0.00016722165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020264045,0.00022383641,0.00019507097,0.00008052676,0.00009910241,0.00007414813,0.0004968418,0.0001278478,0.00002511609],"category_scores_gemma":[0.00052050414,0.0002288142,0.00006936561,0.00032188583,0.00009797053,0.00002076084,0.00016828127,0.00020717694,0.0000049791124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000628266,0.00004426372,0.00013784382,0.0000133220365,0.0000034492857,0.000011680064,0.000029329512,0.00046307416,0.9955108,0.0000583656,0.00032710106,0.0033379183],"study_design_scores_gemma":[0.00021772657,0.00027268752,0.00011651687,0.000017989229,0.0000035749272,0.0000020500656,0.000070565286,0.00065912574,0.99037415,0.000037134585,0.007982832,0.0002456263],"about_ca_topic_score_codex":0.000008224519,"about_ca_topic_score_gemma":5.2820684e-7,"teacher_disagreement_score":0.1168155,"about_ca_system_score_codex":0.000022661501,"about_ca_system_score_gemma":0.00012233747,"threshold_uncertainty_score":0.9330772},"labels":[],"label_agreement":null},{"id":"W3027752863","doi":"10.1074/jbc.ra120.013470","title":"Genetically encoded intrabody sensors report the interaction and trafficking of β-arrestin 1 upon activation of G-protein–coupled receptors","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Biotechnology and Biological Sciences Research Council; Science and Engineering Research Board; The Wellcome Trust DBT India Alliance; Department of Biotechnology, Ministry of Science and Technology, India; National Institute for Health and Care Research; Wellcome Trust","keywords":"Arrestin; Receptor; Cell biology; G protein-coupled receptor; Protein–protein interaction; Chemistry; Biophysics; Biology; Biochemistry","score_opus":0.02280779680171193,"score_gpt":0.25370610403023786,"score_spread":0.23089830722852592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3027752863","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962847,0.00019869691,0.0029857121,0.0003233505,0.000058593934,0.00007548869,0.0000016771604,0.0000031471263,0.00006862626],"genre_scores_gemma":[0.99795544,0.0001472086,0.0015306858,0.000036827405,0.00030016626,0.0000015180174,0.000011763813,0.0000072008356,0.000009197367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99891007,0.00006328554,0.0006021495,0.0001688176,0.00015067244,0.000105019506],"domain_scores_gemma":[0.9988432,0.00004985683,0.00072602043,0.00010178112,0.00019736117,0.00008176156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003849006,0.000115278766,0.00024193308,0.000011483863,0.00003128687,0.000009850324,0.00014231008,0.00019333126,0.000087703076],"category_scores_gemma":[0.00094413554,0.00007262509,0.00012222928,0.00007236253,0.00008623082,0.0000053163158,0.00005176735,0.0002100352,1.2454944e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035793032,0.00003533473,0.00029366315,0.000035862853,0.000048488288,0.0000057461634,0.000059871552,0.0004863017,0.9973121,0.0000054509974,0.00002201069,0.0013371833],"study_design_scores_gemma":[0.00026159847,0.00044171183,0.00016218626,0.00005658044,0.000017212242,0.00009905127,0.0003710658,0.00058446085,0.997401,0.000038817227,0.00048659637,0.00007972675],"about_ca_topic_score_codex":0.0000023475334,"about_ca_topic_score_gemma":1.0575777e-7,"teacher_disagreement_score":0.0016707247,"about_ca_system_score_codex":0.000008757455,"about_ca_system_score_gemma":0.000048058824,"threshold_uncertainty_score":0.2961565},"labels":[],"label_agreement":null},{"id":"W3031076834","doi":"10.1073/pnas.1917906117","title":"In vivo mapping of a GPCR interactome using knockin mice","year":2020,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Interactome; G protein-coupled receptor; In vivo; Computational biology; Receptor; Proteomics; Biology; Cell biology; Neuroscience; Signal transduction; Gene; Genetics","score_opus":0.05468121133262315,"score_gpt":0.3073796021713709,"score_spread":0.25269839083874773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3031076834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99838907,0.00011876799,0.000019930036,0.00076272193,0.00001259022,0.000065806715,0.0000056961903,0.00000102422,0.00062440214],"genre_scores_gemma":[0.99673104,0.00001561805,0.0028470259,0.00031981786,0.00006608595,0.0000012109462,5.6152533e-8,0.0000024501592,0.00001669533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99921834,0.0000042522747,0.00023490275,0.00015107771,0.00031210744,0.000079295285],"domain_scores_gemma":[0.99959606,0.000013327948,0.00025650222,0.0000037194548,0.00011162168,0.000018750126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042463804,0.000052368636,0.00009994339,0.00006283639,0.000032676493,0.0000062178115,0.0003694472,0.00005641712,0.000020734518],"category_scores_gemma":[0.00025006608,0.000039147704,0.000051157193,0.00035326876,0.00014330562,0.00002054764,0.00012305116,0.00006423714,1.16276134e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011527444,0.0000100913885,0.00096861133,0.000038941882,0.0000056578738,2.1945477e-9,0.00022208127,0.00019171578,0.99728584,0.0011377587,0.00009459867,0.000033147782],"study_design_scores_gemma":[0.000094180155,0.000038594655,0.00040751332,0.00006600865,0.0000022954844,0.0000019184538,0.00031099518,0.002397508,0.9947528,0.0015762262,0.00030944616,0.00004247694],"about_ca_topic_score_codex":0.000006474273,"about_ca_topic_score_gemma":3.2333272e-8,"teacher_disagreement_score":0.0028270958,"about_ca_system_score_codex":0.000006842826,"about_ca_system_score_gemma":0.000022906139,"threshold_uncertainty_score":0.1596397},"labels":[],"label_agreement":null},{"id":"W3031364957","doi":"10.1038/s41598-020-65636-3","title":"Signal profiling of the β1AR reveals coupling to novel signalling pathways and distinct phenotypic responses mediated by β1AR and β2AR","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Sherbrooke; McGill University Health Centre; Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Phenotype; Signalling; Signal transduction; Profiling (computer programming); Signalling pathways; Cell biology; Biology; Computational biology; Genetics; Computer science; Gene","score_opus":0.019075897935792844,"score_gpt":0.22627172903671752,"score_spread":0.20719583110092468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3031364957","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98715615,0.0010557058,0.010808056,0.00014050455,0.00040798463,0.00035670536,0.0000374924,0.000013793899,0.000023612907],"genre_scores_gemma":[0.99785954,0.000011778397,0.0017266247,0.0001130834,0.000082446786,0.000011399214,0.0000590665,0.00002079672,0.00011527331],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99821144,0.0000408734,0.0004649555,0.0007235206,0.00031607764,0.00024313708],"domain_scores_gemma":[0.999063,0.000044118235,0.00027142066,0.0002858341,0.00014410148,0.00019150153],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011668012,0.00016384503,0.00021642688,0.00003421916,0.00028670565,0.00010518694,0.00013809721,0.000096127544,0.000025009158],"category_scores_gemma":[0.0006172689,0.00012511459,0.00006148679,0.00022614386,0.00015709948,0.000008032385,0.00021796816,0.000094424344,9.420316e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053470198,0.000021994958,0.0021747185,0.00003577663,0.000017430388,0.0000056623912,0.00021961321,0.00015306774,0.99682385,0.000021242538,0.00033322917,0.00013996879],"study_design_scores_gemma":[0.0001588785,0.00011212405,0.000120407334,0.000056570218,0.000020054615,0.000020205633,0.0001632634,0.0014319445,0.9957624,0.00019596345,0.0017944654,0.00016370283],"about_ca_topic_score_codex":0.0000068771255,"about_ca_topic_score_gemma":0.0000021717124,"teacher_disagreement_score":0.010703387,"about_ca_system_score_codex":0.000007229611,"about_ca_system_score_gemma":0.000102715385,"threshold_uncertainty_score":0.51020247},"labels":[],"label_agreement":null},{"id":"W3035311045","doi":"10.1017/9781108149938.002","title":"Basic Principles in Clinical Neuroendocrinology I: Receptor Mechanisms","year":2018,"lang":"en","type":"book-chapter","venue":"Cambridge University Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Neuroendocrinology; Psychology; Neuroscience; Internal medicine; Medicine; Hormone","score_opus":0.03638555084436683,"score_gpt":0.238883322424633,"score_spread":0.20249777158026616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035311045","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.017857281,0.00021981224,0.0029226714,0.000021826145,0.0013175368,0.000600064,0.00019927954,0.00006223764,0.9767993],"genre_scores_gemma":[0.0035021037,0.00082185824,0.0006755501,0.00017500391,0.0005395593,0.0000018916809,0.00019749011,0.00008652121,0.994],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","domain_scores_codex":[0.99782485,0.00013516174,0.0004493659,0.0009800261,0.00018106677,0.00042953828],"domain_scores_gemma":[0.9986241,0.00003098946,0.000305981,0.00071029755,0.00014579338,0.00018283911],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00016747507,0.0004311387,0.000513634,0.00015197725,0.00010429457,0.000024623298,0.0006238448,0.0007217362,0.0000744594],"category_scores_gemma":[0.000038246424,0.0005063377,0.00035056935,0.000008462908,0.00026839087,0.0000046338414,0.0006985715,0.00051287387,0.00004511531],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000633714,0.000052004114,0.000017467293,0.000069764836,0.0002632337,0.00034827724,0.000019128913,0.0000055974365,0.045712616,0.91864526,0.03162481,0.0026081374],"study_design_scores_gemma":[0.00083687546,0.00051522907,0.000014283745,0.000078588906,0.000066033266,0.000024232304,0.000018439707,0.0000179755,0.037235744,0.000050171933,0.9606478,0.0004945819],"about_ca_topic_score_codex":0.000026681726,"about_ca_topic_score_gemma":0.000011073832,"teacher_disagreement_score":0.929023,"about_ca_system_score_codex":0.000058397723,"about_ca_system_score_gemma":0.00015851132,"threshold_uncertainty_score":0.9997388},"labels":[],"label_agreement":null},{"id":"W3036005652","doi":"10.1089/crispr.2019.0075","title":"CRISPR-Cas9-Mediated Intersectional Knockout of Glycogen Synthase Kinase 3β in D2 Receptor–Expressing Medial Prefrontal Cortex Neurons Reveals Contributions to Emotional Regulation","year":2020,"lang":"en","type":"article","venue":"The CRISPR Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Prefrontal cortex; GSK-3; Neuroscience; Biology; Dopamine receptor D2; Dopamine; Signal transduction; Cell biology; Cognition","score_opus":0.01493371102854703,"score_gpt":0.27730386648603406,"score_spread":0.26237015545748704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036005652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95598406,0.0002789832,0.039682236,0.0027205208,0.0006820286,0.00027862447,0.0002792603,0.000011467223,0.00008284792],"genre_scores_gemma":[0.9971557,0.000051095518,0.0007473685,0.00053144846,0.0012439011,0.000012478442,0.00017930279,0.000025072557,0.000053620788],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814016,0.0003306468,0.0005913626,0.0002915303,0.00034310535,0.000303208],"domain_scores_gemma":[0.9989084,0.00007205792,0.0002766901,0.00016995348,0.0003005929,0.00027228438],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005465536,0.000189324,0.00024680668,0.000089636786,0.00024402149,0.00005650031,0.00028162388,0.0001490758,0.00069347996],"category_scores_gemma":[0.00096407323,0.00015681017,0.00016971733,0.00018621006,0.00008149824,0.000021664764,0.00012555477,0.000381688,0.000017756718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000562643,0.00006791977,0.00034323128,0.000008659381,0.000046884972,0.0000074800623,0.0004259624,0.0008727573,0.9922385,0.00009006401,0.0049178177,0.0004180677],"study_design_scores_gemma":[0.0021753276,0.00091768155,0.011905065,0.00019784292,0.000073567644,0.00020032213,0.0008256895,0.0018144583,0.9753055,0.0004677692,0.0057405448,0.00037625135],"about_ca_topic_score_codex":0.000017491702,"about_ca_topic_score_gemma":0.000020813484,"teacher_disagreement_score":0.04117168,"about_ca_system_score_codex":0.000073315816,"about_ca_system_score_gemma":0.00018778298,"threshold_uncertainty_score":0.7593119},"labels":[],"label_agreement":null},{"id":"W3036044758","doi":"10.1523/eneuro.0028-20.2020","title":"Characterization of a Knock-In Mouse Line Expressing a Fusion Protein of κ Opioid Receptor Conjugated with tdTomato: 3-Dimensional Brain Imaging via CLARITY","year":2020,"lang":"en","type":"article","venue":"eNeuro","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Drug Abuse; Temple University","keywords":"Ventral tegmental area; Neuroscience; Nucleus accumbens; Substantia nigra; Habenula; Interpeduncular nucleus; Tyrosine hydroxylase; Biology; Cell biology; Chemistry; Dopaminergic; Midbrain; Dopamine; Central nervous system","score_opus":0.007840043085340068,"score_gpt":0.21222576619343822,"score_spread":0.20438572310809816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036044758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931605,0.000048641054,0.006159893,0.00030072877,0.000029104112,0.00025257585,0.000028061158,0.000012222518,0.000008275961],"genre_scores_gemma":[0.9974022,0.0000074605537,0.001960545,0.00029960755,0.000057841222,0.000010904145,0.0002051903,0.00002344238,0.000032805292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991045,0.000092814626,0.0002721672,0.00026559987,0.00013873084,0.00012617708],"domain_scores_gemma":[0.9995407,0.000008787156,0.00017993688,0.00012878748,0.00008549875,0.000056288012],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010577973,0.00011940501,0.000179439,0.000034659213,0.00002790095,0.000008607272,0.000087595894,0.00006971459,0.000051743486],"category_scores_gemma":[0.00006943284,0.00010837755,0.000039725,0.00010741744,0.00003317416,0.00000858578,0.00007310644,0.00008837016,8.554143e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033545942,0.000057775444,0.0004554275,0.00006457691,0.000007456593,0.0000031321529,0.00010025222,0.00011600735,0.9982494,0.00000925712,0.000015464637,0.0005858082],"study_design_scores_gemma":[0.0006461111,0.00028273888,0.00015606378,0.00009364487,0.0000035925757,0.0000029855194,0.00001284615,0.0056646154,0.9926484,0.000005935908,0.00037348748,0.00010957038],"about_ca_topic_score_codex":0.000017084785,"about_ca_topic_score_gemma":0.0000024765623,"teacher_disagreement_score":0.005600975,"about_ca_system_score_codex":0.000004546365,"about_ca_system_score_gemma":0.000050298007,"threshold_uncertainty_score":0.44195083},"labels":[],"label_agreement":null},{"id":"W3036464240","doi":"10.1126/sciadv.abb1250","title":"Allosteric pluripotency as revealed by protein kinase A","year":2020,"lang":"en","type":"article","venue":"Science Advances","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Allosteric regulation; Computational biology; Kinase; Protein kinase A; Allosteric enzyme; Cell biology; Biology; Enzyme; Chemistry; Biochemistry","score_opus":0.007970205911920401,"score_gpt":0.24927440117479002,"score_spread":0.24130419526286961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3036464240","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912856,0.0028787584,0.0032586218,0.00083233014,0.0001070645,0.00022623694,0.0000066743914,0.000019239775,0.0013854722],"genre_scores_gemma":[0.99444616,0.000070542694,0.003578652,0.0010528921,0.00011189379,0.000023983348,0.0000082737915,0.000008432804,0.000699196],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895495,0.000018234974,0.00012091,0.00043022324,0.00022730212,0.00024838952],"domain_scores_gemma":[0.99957263,0.0000021526118,0.000059685637,0.00014850615,0.000058837166,0.00015817746],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016105965,0.00009938192,0.00008591932,0.000016906111,0.00014860516,0.000044207187,0.00035473175,0.00003343221,0.00009432069],"category_scores_gemma":[0.00017113739,0.00008440966,0.000035887933,0.00026143898,0.00017249853,0.000022820372,0.00009830436,0.000048534494,0.000037038666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021037591,0.000009471322,0.00004266421,0.000008485543,0.0000015747806,0.000002215875,0.00004476861,0.000014638262,0.9919273,0.00005535627,0.0001997533,0.0076726824],"study_design_scores_gemma":[0.00013172376,0.00039926398,0.000009050875,0.000010442114,0.0000017334295,0.0000026167754,0.00010966162,0.00003048955,0.93309414,0.0002863276,0.06579958,0.00012494907],"about_ca_topic_score_codex":0.00000456374,"about_ca_topic_score_gemma":9.84831e-7,"teacher_disagreement_score":0.06559983,"about_ca_system_score_codex":0.000006801571,"about_ca_system_score_gemma":0.000100965655,"threshold_uncertainty_score":0.3442126},"labels":[],"label_agreement":null},{"id":"W3040483147","doi":"10.14894/medchem.23.1_7","title":"Biased Agonism Of The Mu Opioid Receptor. An Emerging Approach Toward Separation Of Analgesia and Side Effects.","year":2013,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Purdue Pharma (Canada)","funders":"","keywords":"Agonism; Side effect (computer science); Opioid; Pharmacology; Receptor; Medicine; Computer science; Internal medicine; Political science","score_opus":0.012745753474625924,"score_gpt":0.2531064815655554,"score_spread":0.24036072809092945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3040483147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9849609,0.0002550007,0.012830228,0.000038041704,0.000079715996,0.00027765296,0.0000023567698,0.0000053582407,0.0015507408],"genre_scores_gemma":[0.99396056,0.00005867355,0.005656168,0.000062936444,0.000051054747,0.000018043831,0.000037779962,0.0000107840215,0.00014400239],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931747,0.00008087506,0.00018817626,0.00019706675,0.00010281739,0.00011357104],"domain_scores_gemma":[0.9995482,0.000009665424,0.00010474044,0.00022102238,0.000071549824,0.000044807282],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014728095,0.000100015066,0.00013706551,0.000024373752,0.000043746906,0.000014199257,0.00011952198,0.000098833996,0.00003800291],"category_scores_gemma":[0.000026945425,0.00006813797,0.00006383953,0.00006635268,0.000046056,0.000007305945,0.00005529877,0.000043186752,8.688938e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009538658,0.000030246454,0.00026733737,0.000058140697,0.00002341329,2.5594279e-8,0.00015170382,0.000075288706,0.9951447,0.00027293994,0.00010064353,0.003865974],"study_design_scores_gemma":[0.00023695017,0.0001890971,0.0017525867,0.000011347899,0.0000134319525,0.0000012196191,0.0002956517,0.0016844008,0.995347,0.00013532086,0.00024364598,0.000089331246],"about_ca_topic_score_codex":0.00013252602,"about_ca_topic_score_gemma":0.0000031718512,"teacher_disagreement_score":0.008999651,"about_ca_system_score_codex":0.0000033531026,"about_ca_system_score_gemma":0.000023335368,"threshold_uncertainty_score":0.27785856},"labels":[],"label_agreement":null},{"id":"W3040640270","doi":"10.1016/j.schres.2020.06.019","title":"A polymorphism in the glutamate metabotropic receptor 7 is associated with cognitive deficits in the early phases of psychosis","year":2020,"lang":"en","type":"article","venue":"Schizophrenia Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université Paris Descartes; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Psychosis; Glutamatergic; Cohort; Psychology; Single-nucleotide polymorphism; Metabotropic glutamate receptor; Psychiatry; Effects of sleep deprivation on cognitive performance; Cognition; Schizophrenia (object-oriented programming); Medicine; Glutamate receptor; Genotype; Genetics; Internal medicine; Biology; Receptor; Gene","score_opus":0.05800233518595549,"score_gpt":0.32174716945703524,"score_spread":0.26374483427107975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3040640270","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961036,0.0011186753,0.000075531505,0.0018796873,0.00002162944,0.0004949378,0.00006836934,0.00000423477,0.00023337688],"genre_scores_gemma":[0.9988859,0.00018270244,0.00013945515,0.00049861136,0.000091535534,0.00010603053,0.000044098077,0.000018933488,0.00003271997],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99753153,0.000853248,0.00024917335,0.00035707184,0.00062087324,0.00038809385],"domain_scores_gemma":[0.9992675,0.00019539647,0.00007712606,0.00022800764,0.0001777986,0.000054145214],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011943033,0.00014454646,0.00020642816,0.00010231812,0.00010526532,0.00006086452,0.0005340425,0.000119289456,0.00012134553],"category_scores_gemma":[0.00042908324,0.00008340975,0.00007373663,0.0009283014,0.0001454477,0.000007869978,0.00006944524,0.00043850622,0.000011213165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0042980113,0.00041644523,0.0056187846,0.000028522834,0.00018286252,0.000029527082,0.006852184,0.000009298334,0.97564584,0.0006148392,0.0014580507,0.004845662],"study_design_scores_gemma":[0.009677382,0.005234696,0.026404986,0.00040480867,0.000071876224,0.000011927853,0.008060592,0.00017183057,0.94684166,0.0008639739,0.0016949842,0.00056126085],"about_ca_topic_score_codex":0.00022949149,"about_ca_topic_score_gemma":0.00017787472,"teacher_disagreement_score":0.02880413,"about_ca_system_score_codex":0.000010790714,"about_ca_system_score_gemma":0.000104104234,"threshold_uncertainty_score":0.3401351},"labels":[],"label_agreement":null},{"id":"W3043420392","doi":"10.1503/jpn.190171","title":"G-protein coupled receptor 88 knockdown in the associative striatum reduces psychiatric symptoms in a translational male rat model of Parkinson disease","year":2021,"lang":"en","type":"article","venue":"Journal of Psychiatry and Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Sorbonne Université; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche","keywords":"Parkinson's disease; Medicine; Gene knockdown; Striatum; Psychology; Neuroscience; Dopamine; Disease; Biology; Internal medicine; Genetics","score_opus":0.013216506477959153,"score_gpt":0.2513823994163742,"score_spread":0.23816589293841503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3043420392","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99448293,0.0021261002,0.0010821905,0.0015952372,0.0005577796,0.00010672921,0.000016879772,7.6206067e-7,0.00003140725],"genre_scores_gemma":[0.9972075,0.00050580903,0.0018511153,0.00022639082,0.00013174918,0.0000039298006,0.0000028707266,0.0000056266476,0.00006500914],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875,0.00018352488,0.0004066614,0.00022008747,0.00028615858,0.00015362087],"domain_scores_gemma":[0.9994335,0.000021186032,0.0002987714,0.00010184759,0.00007586885,0.00006878831],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005915964,0.00010307881,0.00016359241,0.00008246039,0.000069082416,0.000030337322,0.00020840202,0.00006400693,0.000012888383],"category_scores_gemma":[0.00011466089,0.000077502766,0.00010302005,0.00033381674,0.000057438516,0.000022471551,0.000020442625,0.00019172217,9.776527e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002485387,0.0002540176,0.017214734,0.000017550317,0.000004310293,0.000004055825,0.00012541912,0.0026400553,0.9786458,0.0005851862,0.00008860773,0.0001716987],"study_design_scores_gemma":[0.014857588,0.00487881,0.20752111,0.0010724023,0.00024030903,0.00030130037,0.0034124998,0.094921105,0.6399607,0.028249647,0.0028691872,0.0017153556],"about_ca_topic_score_codex":0.0000019395166,"about_ca_topic_score_gemma":0.000017467493,"teacher_disagreement_score":0.33868515,"about_ca_system_score_codex":0.0000064729866,"about_ca_system_score_gemma":0.00045634827,"threshold_uncertainty_score":0.3160471},"labels":[],"label_agreement":null},{"id":"W3044059177","doi":"10.3389/fphar.2021.633680","title":"COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms","year":2021,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; U.S. Air Force; Defense Advanced Research Projects Agency; Defense Threat Reduction Agency; Advanced Research Projects Agency; National Institutes of Health; Office of Extramural Research, National Institutes of Health; U.S. Department of Defense","keywords":"Famotidine; Medicine; Histamine; Disease; Repurposing; Drug repositioning; Coronavirus disease 2019 (COVID-19); Drug; Pandemic; Histamine receptor; Mechanism of action; Immunology; Pharmacology; Infectious disease (medical specialty); Internal medicine; Receptor; Biology","score_opus":0.008903672197287632,"score_gpt":0.2560673604310783,"score_spread":0.24716368823379067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044059177","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.25148392,0.0071652452,0.7305941,0.001541304,0.0075490894,0.00040984192,0.00007878539,0.000041861233,0.0011358804],"genre_scores_gemma":[0.90778154,0.0035700821,0.072056875,0.010955771,0.00053077476,0.000086098196,0.00025644997,0.00006926745,0.004693156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872726,0.00015282487,0.0002170933,0.0004892367,0.000085374115,0.00032818696],"domain_scores_gemma":[0.9994486,0.000012902253,0.00006204318,0.00014838028,0.000043423133,0.00028466017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022124551,0.00017100867,0.00022729643,0.00008433534,0.000081013495,0.000016512478,0.00014017712,0.00019802904,0.00071980467],"category_scores_gemma":[0.00006262265,0.00018803938,0.00005735824,0.00012489229,0.000071787654,0.000004359399,0.00014748606,0.0001416681,0.0000032440491],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006807541,0.000057450492,0.00034845524,0.000032645392,0.00004836582,0.00010327877,0.000044439017,0.00015426731,0.91815156,0.00041040496,0.07962912,0.000951915],"study_design_scores_gemma":[0.0012084827,0.000102487065,0.000027487986,0.0000027306285,0.000026415784,0.000039842536,0.000298969,0.000561211,0.80515707,0.0015369261,0.19084245,0.00019591932],"about_ca_topic_score_codex":0.000011475047,"about_ca_topic_score_gemma":0.000013009713,"teacher_disagreement_score":0.6585372,"about_ca_system_score_codex":0.0000599113,"about_ca_system_score_gemma":0.0002585407,"threshold_uncertainty_score":0.7881356},"labels":[],"label_agreement":null},{"id":"W3044480534","doi":"10.15252/embr.201949886","title":"Key phosphorylation sites in GPCRs orchestrate the contribution of β‐Arrestin 1 in ERK1/2 activation","year":2020,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Instituto de Salud Carlos III; Science and Engineering Research Board; Japan Society for the Promotion of Science; Canadian Institutes of Health Research; Ministry of Education, Culture, Sports, Science and Technology; Wellcome Trust; Council of Scientific and Industrial Research, India; Fonds de Recherche du Québec - Santé; Department of Science and Technology, Ministry of Science and Technology, India; Department of Biotechnology, Ministry of Science and Technology, India; Indian Institute of Technology Kanpur; The Wellcome Trust DBT India Alliance; Government of Canada; Narodowe Centrum Nauki; Japan Agency for Medical Research and Development","keywords":"Phosphorylation; G protein-coupled receptor; Arrestin; MAPK/ERK pathway; Key (lock); Cell biology; Chemistry; Biology; Signal transduction; Ecology","score_opus":0.016315109932515687,"score_gpt":0.24069749677997773,"score_spread":0.22438238684746203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044480534","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99738336,0.00014187836,0.0017147603,0.00031390123,0.000047684232,0.00017968345,8.769308e-7,0.0000044947737,0.0002133726],"genre_scores_gemma":[0.9995441,0.00001971664,0.00014219525,0.00009302977,0.000061019295,0.000011841784,0.00010626626,0.000006570728,0.000015284231],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99927294,0.000050481933,0.0002973324,0.00018403494,0.00009548885,0.0000996918],"domain_scores_gemma":[0.99961317,0.000013852069,0.00018211186,0.000114661874,0.000051669977,0.000024548532],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033940934,0.00006891919,0.00009879501,0.0000192062,0.00001975454,0.000009397397,0.00004138512,0.000083341925,0.000029030027],"category_scores_gemma":[0.0003650766,0.000056219684,0.000032127944,0.0001364655,0.000016342763,0.000005535279,0.000021770375,0.000075368655,6.9450687e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044064956,0.00001636857,0.02964857,0.000005248478,0.000004734139,0.000009695251,0.00017348373,0.0017181744,0.96775275,0.000115493276,0.00007091123,0.00044050932],"study_design_scores_gemma":[0.00016949131,0.00007111197,0.01893695,0.00001967755,0.000003007335,0.0000049215796,0.000085478576,0.0007470386,0.9786939,0.00041586044,0.00078564166,0.00006692311],"about_ca_topic_score_codex":0.00006711818,"about_ca_topic_score_gemma":0.000046426645,"teacher_disagreement_score":0.0109411515,"about_ca_system_score_codex":0.0000129158625,"about_ca_system_score_gemma":0.00005423443,"threshold_uncertainty_score":0.22925721},"labels":[],"label_agreement":null},{"id":"W3045441955","doi":"10.1074/jbc.ra120.014330","title":"Angiotensin II type 1 receptor variants alter endosomal receptor–β-arrestin complex stability and MAPK activation","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; McGill University Health Centre; Government of Canada; McGill University","keywords":"Arrestin; Angiotensin II; MAPK/ERK pathway; Receptor; Endosome; Endocrinology; Internal medicine; Cell biology; Angiotensin receptor; Chemistry; G protein-coupled receptor; Biology; Medicine; Signal transduction","score_opus":0.05186574647556081,"score_gpt":0.2560760098753829,"score_spread":0.20421026339982212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3045441955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9975366,0.00025550366,0.00083510083,0.0010064665,0.00011641684,0.000070414884,0.000019126897,0.000009324004,0.0001510307],"genre_scores_gemma":[0.99300605,0.00015800996,0.005229106,0.0005113857,0.0009749128,0.0000010298137,0.0000815643,0.000012014704,0.000025944728],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99886894,0.0000775567,0.00040430328,0.00029756746,0.00014704268,0.0002045815],"domain_scores_gemma":[0.99910945,0.000032882424,0.00028778138,0.00012246374,0.0002182213,0.00022917826],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002659336,0.0001782366,0.000280661,0.000009705285,0.00009480871,0.000025925445,0.00017734294,0.00028083357,0.0012684589],"category_scores_gemma":[0.00052557304,0.00013382651,0.00011640463,0.00008595797,0.0000896511,0.000009104194,0.00015014243,0.0002456228,0.0000037636914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005352322,0.00005851605,0.00089033437,0.000018061966,0.000044099572,0.0000030716708,0.000047212787,0.000005563134,0.9950952,0.000005099281,0.0025247007,0.00077293103],"study_design_scores_gemma":[0.00050303264,0.0007700485,0.0007637055,0.00002061746,0.000010222755,0.000032139877,0.000098935845,0.000045647444,0.982053,0.00004421454,0.015494257,0.00016422622],"about_ca_topic_score_codex":0.0000016332928,"about_ca_topic_score_gemma":7.6806515e-8,"teacher_disagreement_score":0.0130422255,"about_ca_system_score_codex":0.00001913328,"about_ca_system_score_gemma":0.000059627004,"threshold_uncertainty_score":0.9996445},"labels":[],"label_agreement":null},{"id":"W3047030547","doi":"10.1186/s12885-020-07193-6","title":"Antagonists of the serotonin receptor 5A target human breast tumor initiating cells","year":2020,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research; McMaster University","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Stem Cell Network; Ontario Institute for Cancer Research","keywords":"Cancer research; Breast cancer; In vivo; Biology; Mammary tumor; Cancer; Receptor; Genetics","score_opus":0.018638735908710586,"score_gpt":0.25410859234305927,"score_spread":0.23546985643434867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047030547","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99733484,0.00035958638,0.000845737,0.00020384464,0.00029989914,0.0002379092,0.00020566583,0.000010011151,0.0005024834],"genre_scores_gemma":[0.9968905,0.000018661693,0.0015848574,0.0007082409,0.00052597787,0.000032616234,0.000030242007,0.000023921304,0.0001849774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992351,0.00005395403,0.00019295051,0.00023336569,0.00012125219,0.00016335645],"domain_scores_gemma":[0.99956155,0.0000048839743,0.00014376752,0.00016797792,0.00005844321,0.00006337142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008256438,0.00011362173,0.00013200677,0.000007589097,0.000097804965,0.000017352953,0.00020744697,0.00005978211,0.00078326545],"category_scores_gemma":[0.000015642727,0.00008789649,0.00010858351,0.00007778824,0.00004089,0.000003039523,0.000113450624,0.0000799034,0.0000052188034],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002994866,0.000011951655,0.0038210757,0.000046397065,0.000016375741,2.8531318e-7,0.000112728056,0.00024391069,0.9935279,0.000056751516,0.0020304406,0.00010221742],"study_design_scores_gemma":[0.00026027756,0.00006483388,0.00045189096,0.000032446387,0.000008573459,0.00000219128,0.00010655913,0.000108244356,0.9873271,0.00001672078,0.0115028415,0.000118293996],"about_ca_topic_score_codex":0.0000959421,"about_ca_topic_score_gemma":0.000035746703,"teacher_disagreement_score":0.009472401,"about_ca_system_score_codex":0.000012336032,"about_ca_system_score_gemma":0.00011598652,"threshold_uncertainty_score":0.8576207},"labels":[],"label_agreement":null},{"id":"W3048086364","doi":"10.1016/j.isci.2020.101447","title":"Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands","year":2020,"lang":"en","type":"article","venue":"iScience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Jewish General Hospital","funders":"National Research Council Canada; Canadian Institutes of Health Research; Consortium canadien en neurodégénérescence associée au vieillissement","keywords":"Ectodomain; Gene isoform; Intracellular; Cell biology; Chemistry; Signal transduction; Alternative splicing; Receptor; Biochemistry; Biology; Biophysics; Gene","score_opus":0.01575562618408611,"score_gpt":0.22765677135256418,"score_spread":0.21190114516847808,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3048086364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7580092,0.00018451147,0.24105898,0.0001898331,0.00013326951,0.00012141106,0.000011128545,0.000008648661,0.000283047],"genre_scores_gemma":[0.9979246,0.000077536264,0.001409542,0.00026941235,0.00021195864,0.000013002778,0.000031696338,0.000009016564,0.000053179967],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896806,0.000026848937,0.00025570174,0.00029181846,0.0002429202,0.00021463886],"domain_scores_gemma":[0.9994927,0.00002354448,0.00015018591,0.00011952475,0.00010996563,0.00010410325],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022936963,0.00013078717,0.00015229719,0.000043916414,0.00014268789,0.000031707576,0.00020057583,0.000079163736,0.00010454255],"category_scores_gemma":[0.000102319136,0.00011106185,0.0000790316,0.00018317669,0.00008486158,0.000017986631,0.000098478624,0.00011053419,0.0000074349887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057687088,0.000021453261,0.00021450003,0.000012286315,0.000019999594,4.6848814e-7,0.00090354914,0.0011033154,0.99531966,0.0013374062,0.00016309311,0.0008465921],"study_design_scores_gemma":[0.000305315,0.00029914756,0.000084929176,0.000021323516,0.0000058634178,0.000003387878,0.00065256585,0.0029712485,0.9939213,0.00052639283,0.0010717682,0.00013677742],"about_ca_topic_score_codex":0.000014898509,"about_ca_topic_score_gemma":0.0000031681313,"teacher_disagreement_score":0.23991548,"about_ca_system_score_codex":0.000021034819,"about_ca_system_score_gemma":0.00007090637,"threshold_uncertainty_score":0.45289707},"labels":[],"label_agreement":null},{"id":"W3066049608","doi":"10.1073/pnas.2003787117","title":"Agonist-induced formation of unproductive receptor-G <sub>12</sub> complexes","year":2020,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; National Institute of Mental Health; Canadian Institutes of Health Research; Svenska Sällskapet för Medicinsk Forskning; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Government of Canada; Japan Agency for Medical Research and Development","keywords":"Heterotrimeric G protein; G protein-coupled receptor; Agonist; G protein; Receptor; Chemistry; G beta-gamma complex; Cell biology; Signal transduction; Ternary complex; Biochemistry; Biology","score_opus":0.048008459824509034,"score_gpt":0.27800168509449646,"score_spread":0.22999322526998744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3066049608","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99717677,0.000066101886,0.000025716523,0.001680939,0.000017341446,0.00017854017,0.000016780663,0.0000035858743,0.0008342012],"genre_scores_gemma":[0.99859995,0.000032569238,0.0010220767,0.00019353321,0.00013237703,0.000006535846,0.0000013487329,0.000003669461,0.000007959969],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989127,0.000007368599,0.0002726353,0.00019978767,0.0005112331,0.000096262695],"domain_scores_gemma":[0.9992398,0.000012997549,0.00042132317,0.0000074797963,0.00028857286,0.0000297997],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049818156,0.00007601024,0.000121956095,0.000039887003,0.00010372421,0.000010401224,0.00041470048,0.00007395266,0.0000072735843],"category_scores_gemma":[0.00034222825,0.000055541223,0.00007450567,0.00025836576,0.0002487412,0.00003469559,0.00011114941,0.000072877854,6.5403566e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026900185,0.000015274014,0.000111385256,0.00004766076,0.000009602615,4.5423773e-10,0.00017399759,0.000059090242,0.99379176,0.00484064,0.0005445392,0.00037915946],"study_design_scores_gemma":[0.00011345413,0.0001537454,0.00051921466,0.00003189578,0.000005725852,0.0000011646359,0.0002763727,0.00028178777,0.995166,0.0031483097,0.00024091717,0.000061406994],"about_ca_topic_score_codex":0.0000014114929,"about_ca_topic_score_gemma":3.4179077e-8,"teacher_disagreement_score":0.0016923303,"about_ca_system_score_codex":0.000008279822,"about_ca_system_score_gemma":0.000028185908,"threshold_uncertainty_score":0.22649054},"labels":[],"label_agreement":null},{"id":"W3077605905","doi":"10.1016/j.molcel.2020.08.001","title":"Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound β1-Adrenergic Receptor","year":2020,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Center for Research Resources; National Institute of General Medical Sciences; National Institute on Drug Abuse; National Institutes of Health; National Cancer Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Heterotrimeric G protein; Biology; Helix (gastropod); Contractility; Receptor; Cell biology; G protein; G protein-coupled receptor; Regulator; Adrenergic receptor; Biophysics; Protein structure; Biochemistry; Endocrinology; Gene","score_opus":0.008269874856863866,"score_gpt":0.1963895758624705,"score_spread":0.18811970100560663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3077605905","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939872,0.00046653443,0.004679916,0.00016106368,0.00006575791,0.00030248627,0.000026482307,0.0000058004566,0.00030476754],"genre_scores_gemma":[0.9984744,0.000011246396,0.0009982244,0.00023144252,0.000048955262,0.000013809146,0.0000659992,0.000026554828,0.00012934807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989937,0.000095626434,0.00026337747,0.0002849811,0.00020194269,0.00016038715],"domain_scores_gemma":[0.9993396,0.000003361863,0.00023184958,0.00029283634,0.00007205308,0.00006031864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059125632,0.00015965405,0.00018018315,0.000017726712,0.000047632217,0.000012736745,0.00028550738,0.00013019588,0.00018834861],"category_scores_gemma":[0.000033171305,0.00012659667,0.00017711562,0.00015506867,0.000058577443,0.0000042726374,0.00011691014,0.000091053,0.000002609608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055151108,0.000016899043,0.00005670439,0.00004434658,0.000030431742,2.4793937e-7,0.000060513037,0.00023628295,0.99849117,0.000023253384,0.00023623192,0.00074874674],"study_design_scores_gemma":[0.0003578545,0.00027904857,0.000016406573,0.000016709908,0.000014773998,3.977337e-7,0.000041644926,0.00015435822,0.9974209,0.000041704963,0.0015192408,0.00013692722],"about_ca_topic_score_codex":0.000049323666,"about_ca_topic_score_gemma":4.7263802e-7,"teacher_disagreement_score":0.0044872286,"about_ca_system_score_codex":0.000008382707,"about_ca_system_score_gemma":0.000042145137,"threshold_uncertainty_score":0.51624626},"labels":[],"label_agreement":null},{"id":"W3079012346","doi":"10.21769/bioprotoc.3715","title":"Assessing Gαq/15-signaling with IP-One: Single Plate Transfection and Assay Protocol for Cell-Based High-Throughput Assay","year":2020,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke; McGill University","funders":"Faculty of Medicine and Health, University of Sydney; Canadian Institutes of Health Research; Réseau québécois de recherche sur la douleur; Université de Sherbrooke","keywords":"Transfection; High-throughput screening; HEK 293 cells; Mutant; Ligand binding assay; Cell culture; Receptor; G protein-coupled receptor; Chemistry; Cell biology; Molecular biology; Computational biology; Biology; Biochemistry; Gene; Genetics","score_opus":0.04214115711114128,"score_gpt":0.3030761444771193,"score_spread":0.260934987365978,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3079012346","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0026028212,0.0000012130556,0.3621178,0.00017203411,0.000025904941,0.6348549,0.0000150779,0.000057727582,0.00015248221],"genre_scores_gemma":[0.07214493,7.124507e-8,0.026403995,0.00039208986,0.00045961363,0.90041745,0.00005599638,0.00008733001,0.000038508442],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978015,0.00020156865,0.00043940498,0.00082568586,0.0002825924,0.00044925002],"domain_scores_gemma":[0.9990697,0.000053276373,0.00024415465,0.00025633312,0.00016743761,0.00020908227],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00058027223,0.00039498694,0.00034148875,0.000051418257,0.00031201972,0.00030325507,0.00017776318,0.00034106494,0.00012836192],"category_scores_gemma":[0.000055265842,0.00033786052,0.0001346239,0.00016576766,0.000075208016,0.000036141148,0.000043368964,0.00018253236,0.0000032173862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014476363,0.00022257086,0.00015125301,0.00079693785,0.000044812117,0.000003868229,0.00004733487,0.0005014009,0.99281377,0.000026338254,0.0003090716,0.0036350302],"study_design_scores_gemma":[0.007198876,0.0031299265,0.000029976116,0.0001656372,0.000034480465,0.0000039950814,0.000058152338,0.001850381,0.9281268,0.00006038729,0.0588625,0.00047890528],"about_ca_topic_score_codex":0.000019619307,"about_ca_topic_score_gemma":0.000007989118,"teacher_disagreement_score":0.3357138,"about_ca_system_score_codex":0.0000354167,"about_ca_system_score_gemma":0.00018731508,"threshold_uncertainty_score":0.9999073},"labels":[],"label_agreement":null},{"id":"W3080146684","doi":"10.3389/fendo.2020.00529","title":"Corticotropin-Releasing Factor: An Ancient Peptide Family Related to the Secretin Peptide Superfamily","year":2020,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Secretin; SUPERFAMILY; Peptide; Secretin family; Biology; Internal medicine; Endocrinology; Medicine; Genetics; Biochemistry; Neuropeptide; Pancreas; Gene; Receptor; Vasoactive intestinal peptide","score_opus":0.016980370848085957,"score_gpt":0.24308817578504813,"score_spread":0.22610780493696217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3080146684","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9733246,0.0021320526,0.021310052,0.0011068411,0.001162546,0.00036903843,0.000022149014,0.00004257771,0.0005301189],"genre_scores_gemma":[0.98742914,0.0008024812,0.0070797415,0.0041228128,0.00022236076,0.000034634944,0.00007662351,0.00004729901,0.0001848773],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978394,0.00021935932,0.0004065476,0.0006700423,0.00017324853,0.00069138804],"domain_scores_gemma":[0.999207,0.000011489243,0.00008053235,0.0004146022,0.000060595397,0.00022576538],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000037049627,0.00025538058,0.0003140868,0.00008082766,0.00013077681,0.000035316123,0.0004968373,0.00016436694,0.000055544682],"category_scores_gemma":[0.00014784068,0.00021704311,0.000107506356,0.00021781707,0.00009626418,0.000009241467,0.00019914084,0.0003204656,0.000036047735],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021279232,0.0000455264,0.014869053,0.000010421052,0.00006329978,0.000042548487,0.0011454864,0.0021725355,0.95723414,0.0002161074,0.013704391,0.010283695],"study_design_scores_gemma":[0.0029154276,0.0035135185,0.06006725,0.000052119784,0.000065244414,0.000101794896,0.011358401,0.007371697,0.29217064,0.00037976765,0.6205759,0.0014282059],"about_ca_topic_score_codex":0.00006110781,"about_ca_topic_score_gemma":0.00002580355,"teacher_disagreement_score":0.6650635,"about_ca_system_score_codex":0.000048339327,"about_ca_system_score_gemma":0.00008215214,"threshold_uncertainty_score":0.8850761},"labels":[],"label_agreement":null},{"id":"W3080525347","doi":"10.1503/jpn.200149","title":"Orphans to the rescue: orphan G-protein coupled receptors as new antidepressant targets","year":2020,"lang":"en","type":"editorial","venue":"Journal of Psychiatry and Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Receptor; Antidepressant; G protein-coupled receptor; Psychiatry; Medicine; Pharmacology; Bioinformatics; Neuroscience; Computational biology; Biology; Internal medicine","score_opus":0.008945267896238387,"score_gpt":0.2591613551019345,"score_spread":0.2502160872056961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3080525347","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.039171375,0.00444827,0.0057548434,0.0077667176,0.94234955,0.00041028444,0.00003776212,0.000010205044,0.000050976007],"genre_scores_gemma":[0.02031724,0.0037777976,0.0043693422,0.0036813586,0.9648967,0.0000094279685,0.00002248994,0.00010299095,0.0028226564],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975993,0.00014540926,0.0005634316,0.0005650937,0.0007917059,0.0003350553],"domain_scores_gemma":[0.99838173,0.000033351804,0.00049778796,0.00032380084,0.00018755459,0.00057579455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006820096,0.00031677357,0.00038085366,0.00008195073,0.00027685464,0.0001831327,0.00096456666,0.00034231745,0.00004729997],"category_scores_gemma":[0.0017056532,0.00021412589,0.00021252742,0.00026115653,0.000089759546,0.000016570604,0.00022103156,0.00072576787,0.0000071490576],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021017056,0.00002354138,0.000013372025,0.000018517414,0.000012562998,0.000012772047,0.000031431144,0.00007144761,0.39329112,0.000027331855,0.60610026,0.00018749101],"study_design_scores_gemma":[0.0004400392,0.002196762,0.000014818409,0.0001495107,0.00004445201,0.00006221923,0.000050100643,0.000028260883,0.053897586,0.0001772,0.94267,0.00026904957],"about_ca_topic_score_codex":0.000031992135,"about_ca_topic_score_gemma":0.000028688813,"teacher_disagreement_score":0.33939353,"about_ca_system_score_codex":0.0000102521135,"about_ca_system_score_gemma":0.0013759622,"threshold_uncertainty_score":0.87318003},"labels":[],"label_agreement":null},{"id":"W3081083304","doi":"10.1016/j.neuropharm.2020.108286","title":"Impact of T161, Y318 and S363 alanine mutations on regulation of the human delta-opioid receptor (hDOPr) induced by peptidic and alkaloid agonists","year":2020,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministère de l'Éducation et de l'Enseignement supérieur","keywords":"Etorphine; Enkephalin; Internalization; Chemistry; Context (archaeology); Agonist; Receptor; Desensitization (medicine); Opioid receptor; Opioid; Internal medicine; Endocrinology; Biology; Biochemistry; (+)-Naloxone; Medicine","score_opus":0.01553863144125335,"score_gpt":0.28292702828796684,"score_spread":0.2673883968467135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081083304","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991531,0.00014675948,0.00002728304,0.0002409927,0.00009773834,0.00020485453,0.000056364956,0.0000060744155,0.0000668615],"genre_scores_gemma":[0.9992543,0.00010737271,0.000049036422,0.0003571035,0.000095316565,0.0000075799285,0.00006762402,0.000018725594,0.000042960368],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991709,0.00013548999,0.00022198807,0.00025750414,0.00008611784,0.00012802373],"domain_scores_gemma":[0.99954593,0.000028713022,0.00017143028,0.00011015666,0.00006384511,0.00007995242],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006304817,0.00012757287,0.00017247227,0.000025648409,0.00008656229,0.000006927435,0.0001049014,0.000099630066,0.00011130394],"category_scores_gemma":[0.00005914305,0.000099896104,0.000067120905,0.00008521133,0.00009781792,0.0000039452943,0.00008088886,0.00011271381,9.4859945e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010406167,0.000040924144,0.0010627722,0.000018485476,0.000045035773,4.130479e-7,0.00011857478,0.00005925366,0.99663,0.00004403991,0.0013564164,0.00052003213],"study_design_scores_gemma":[0.0008455756,0.0015728854,0.014000162,0.000005809639,0.00003626618,0.000004306857,0.000014857552,0.0001381325,0.9823393,0.00002682329,0.0009271031,0.00008874462],"about_ca_topic_score_codex":0.000023317982,"about_ca_topic_score_gemma":0.0000014714478,"teacher_disagreement_score":0.014290657,"about_ca_system_score_codex":0.0000068405443,"about_ca_system_score_gemma":0.000037336784,"threshold_uncertainty_score":0.4073645},"labels":[],"label_agreement":null},{"id":"W3081143834","doi":"10.3389/fphar.2020.01283","title":"Interplay Between Angiotensin II Type 1 Receptor and Thrombin Receptor Revealed by Bioluminescence Resonance Energy Transfer Assay","year":2020,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut National de la Recherche Agronomique; Augusta University; United Arab Emirates University; McGill University","keywords":"Bioluminescence; Receptor; Thrombin; Energy transfer; Thrombin receptor; Angiotensin II; Chemistry; Förster resonance energy transfer; Pharmacology; Biophysics; Internal medicine; Cell biology; Biology; Medicine; Biochemistry; Physics; Fluorescence; Platelet","score_opus":0.009491938585240136,"score_gpt":0.2523278909851217,"score_spread":0.24283595239988157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081143834","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.90350026,0.014504959,0.07452645,0.0038377244,0.002906701,0.00038190186,0.0001747305,0.00004727482,0.00012001206],"genre_scores_gemma":[0.98033756,0.003814,0.010876652,0.0031672372,0.0007432092,0.000028560506,0.0003419223,0.000056693672,0.0006341602],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982606,0.00026126916,0.00033632683,0.0006420078,0.000103519444,0.0003962879],"domain_scores_gemma":[0.9995357,0.000020266085,0.000057738063,0.00012847423,0.00006574037,0.00019208438],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002486765,0.0002508662,0.00039319103,0.000056246605,0.000096630436,0.000014218638,0.00026486762,0.0003243288,0.0003547383],"category_scores_gemma":[0.0000446907,0.00025920192,0.00006944901,0.00023461241,0.00014785967,0.000011208563,0.00012562853,0.00021192366,0.0000039705515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025293077,0.000026163369,0.0025403362,0.000008381985,0.000051538736,0.0000021832852,0.00012136107,0.0000068362565,0.6656319,0.0000066268776,0.32782227,0.0035295002],"study_design_scores_gemma":[0.0009270737,0.0005793996,0.000042692838,0.000015319956,0.000025671958,0.000002267001,0.000059657752,0.0004061198,0.65661633,0.000012469765,0.3410523,0.0002607041],"about_ca_topic_score_codex":0.00002277565,"about_ca_topic_score_gemma":0.0000026023588,"teacher_disagreement_score":0.07683732,"about_ca_system_score_codex":0.000030198049,"about_ca_system_score_gemma":0.000055334727,"threshold_uncertainty_score":0.999986},"labels":[],"label_agreement":null},{"id":"W3081180842","doi":"10.1139/cjpp-2020-0149","title":"Biased signaling in platelet G-protein coupled receptors","year":2020,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Platelet; G protein-coupled receptor; Signal transduction; Platelet activation; Receptor; Cell biology; Biology; Platelet Glycoprotein GPIb-IX Complex; Protease-activated receptor; Neuroscience; Immunology; Thrombin; Biochemistry","score_opus":0.025525499585106484,"score_gpt":0.2900670460716256,"score_spread":0.2645415464865191,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3081180842","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03285031,0.96555024,0.000024941062,0.000072830546,0.0011356045,0.0003168272,0.000029235587,0.0000022134543,0.000017785085],"genre_scores_gemma":[0.020902833,0.9771936,0.00016456518,0.0003496693,0.0011712621,0.000021069547,0.00009948562,0.000050472707,0.000047050195],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99797326,0.00047507734,0.0007133008,0.00035621691,0.000055400527,0.00042674868],"domain_scores_gemma":[0.9987141,0.000062651015,0.0005314557,0.000097120304,0.00007899595,0.00051566603],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00037757395,0.00034818173,0.0013077057,0.00030999526,0.000090546666,0.000013530858,0.00034085402,0.0006578983,0.0016684082],"category_scores_gemma":[0.000062180094,0.00031001287,0.00029022802,0.00017850824,0.00015478989,0.0000057349584,0.000037317277,0.00074325886,0.000008902241],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010791297,0.000021744632,0.000004213704,0.001992742,0.00052044773,0.00037252373,0.00008643287,0.0000540052,0.9026661,0.000039159047,0.0018388805,0.09229585],"study_design_scores_gemma":[0.0006433503,0.00048955996,6.2793663e-7,0.0006449642,0.00017028439,0.0001648536,0.000020723814,0.000013070205,0.050361916,0.00010568673,0.94707483,0.0003101449],"about_ca_topic_score_codex":0.0001381056,"about_ca_topic_score_gemma":0.00023748637,"teacher_disagreement_score":0.9452359,"about_ca_system_score_codex":0.00005849333,"about_ca_system_score_gemma":0.0018372835,"threshold_uncertainty_score":0.9999352},"labels":[],"label_agreement":null},{"id":"W3084137844","doi":"10.1101/2020.09.09.289280","title":"Myogenic Vasoconstriction Requires Canonical G <sub>q/11</sub> Signaling of the Angiotensin II Type 1a Receptor in the Murine Vasculature","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Vasoconstriction; Myogenic contraction; Angiotensin II; Mesenteric arteries; Internal medicine; Endocrinology; Cerebral arteries; Receptor; Signal transduction; Gq alpha subunit; Chemistry; Cell biology; Biology; G protein; Medicine; Artery; Smooth muscle","score_opus":0.012044435424542409,"score_gpt":0.20809100732867802,"score_spread":0.1960465719041356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3084137844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943473,0.0025117428,0.00044955369,0.0006319062,0.0011769644,0.000754337,0.00008486256,0.000039770413,0.0000036155477],"genre_scores_gemma":[0.99680257,0.00057333615,0.0011119138,0.00039797183,0.00097175955,0.000049269944,0.0000038771263,0.00008685403,0.0000024457088],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99717414,0.00039395923,0.000638696,0.0008954634,0.00045464924,0.00044311164],"domain_scores_gemma":[0.99775934,0.000040713487,0.000474677,0.001186554,0.0004187688,0.00011993659],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00071993,0.0004821444,0.00049681467,0.00009556506,0.00021826442,0.000079510806,0.00086280867,0.0008703439,0.000024900895],"category_scores_gemma":[0.00030983213,0.00036111625,0.00043894237,0.0006635099,0.00014857954,0.0000104732135,0.000765496,0.0008328064,0.000004668765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050585728,0.00007828754,0.0010659843,0.00008193856,0.00014631024,0.000006321701,0.000025478674,0.00043015025,0.99709946,0.00025717422,0.0007517931,0.0000065295603],"study_design_scores_gemma":[0.0003739408,0.00012822772,0.0037153307,0.00026087087,0.00012870504,1.0257963e-7,0.0000120830055,0.00010241254,0.98973346,0.000005251151,0.00512526,0.0004143837],"about_ca_topic_score_codex":0.00006245977,"about_ca_topic_score_gemma":0.000019389423,"teacher_disagreement_score":0.0073660146,"about_ca_system_score_codex":0.000077986326,"about_ca_system_score_gemma":0.0007701124,"threshold_uncertainty_score":0.99988407},"labels":[],"label_agreement":null},{"id":"W3084312057","doi":"10.1093/oxfordhb/9780190686307.013.12","title":"Regulation of Protein Synthesis by eIF4E in the Brain","year":2020,"lang":"en","type":"book-chapter","venue":"Oxford University Press eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"","keywords":"EIF4E; Translation (biology); Protein biosynthesis; Synaptic plasticity; Function (biology); Neuroscience; Limiting; Biology; Neuroplasticity; Messenger RNA; Cell biology; Gene; Biochemistry; Receptor","score_opus":0.012995289434181998,"score_gpt":0.1845644551259831,"score_spread":0.1715691656918011,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3084312057","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0040215356,0.00016205008,0.0011745476,0.0001262617,0.0000323505,0.00061493885,0.00014568235,0.00001047389,0.9937122],"genre_scores_gemma":[0.15534501,0.00010634767,0.0003946521,0.00012640978,0.00010495487,0.000004331373,0.00017262301,0.000044263426,0.8437014],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993125,0.000055626355,0.00013001052,0.00026000975,0.00014272085,0.00009910816],"domain_scores_gemma":[0.9995083,0.000019943654,0.00015484836,0.00025074606,0.000034869016,0.000031291856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000115523435,0.00015581273,0.00017699745,0.000034803594,0.000043909982,0.000009959009,0.00031813246,0.0002823584,0.00002730313],"category_scores_gemma":[0.000015752126,0.00014513072,0.00011584242,0.000005653805,0.000057473637,0.0000022154259,0.00010766044,0.00013561492,1.6909759e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002582404,0.000015179185,0.0000015118222,0.00009952985,0.000105309045,0.0000114145405,0.0001618538,0.00001152568,0.76308036,0.22617915,0.0042435615,0.0058323517],"study_design_scores_gemma":[0.00015045985,0.000082529245,0.0000015844853,0.00006653231,0.000028195895,9.150129e-7,0.000040984458,0.00001542696,0.1818068,0.0003354487,0.81733453,0.00013658688],"about_ca_topic_score_codex":0.000021689117,"about_ca_topic_score_gemma":0.0000085212205,"teacher_disagreement_score":0.813091,"about_ca_system_score_codex":0.000015004686,"about_ca_system_score_gemma":0.000036153415,"threshold_uncertainty_score":0.5918259},"labels":[],"label_agreement":null},{"id":"W3084368441","doi":"10.1038/s41386-020-00859-6","title":"Habenular TCF7L2 links nicotine addiction to diabetes: the broad significance","year":2020,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute on Drug Abuse; Canadian Institutes of Health Research","keywords":"Nicotine; Addiction; Psychology; TCF7L2; Diabetes mellitus; Neuroscience; Psychiatry; Medicine; Pharmacology; Endocrinology; Biology","score_opus":0.013047709797755927,"score_gpt":0.2604308431221319,"score_spread":0.24738313332437595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3084368441","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9745851,0.0005529108,0.00386981,0.018415228,0.0013991889,0.00058396877,0.000028907109,0.000063340914,0.00050154945],"genre_scores_gemma":[0.93047816,0.00016904835,0.00027879246,0.06711228,0.0016976118,0.00007766225,0.000027264374,0.00004501021,0.00011418641],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985159,0.0001938735,0.0002466654,0.00057284586,0.00013428328,0.00033639875],"domain_scores_gemma":[0.999331,0.000026451846,0.00008699358,0.00021653649,0.00006651037,0.0002725143],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010662923,0.00019870202,0.00017723243,0.000021005313,0.00012804454,0.000027122045,0.0004114577,0.00017909246,0.0004578455],"category_scores_gemma":[0.00009293953,0.00016425036,0.00010720639,0.00021565131,0.000051121187,0.0000037848868,0.00011969058,0.0003916335,0.00021294154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020923268,0.000027309961,0.0001587269,0.000006774541,0.00004457978,0.0000039589613,0.0000710327,0.00060406374,0.94868237,0.000015342866,0.045193754,0.0049828733],"study_design_scores_gemma":[0.00061859045,0.0009531867,0.00035592727,0.0000027586755,0.000033387834,0.0000019319632,0.000015504846,0.00092797703,0.5733765,0.0000087133185,0.4235421,0.00016344296],"about_ca_topic_score_codex":0.0000018017595,"about_ca_topic_score_gemma":0.0000010253692,"teacher_disagreement_score":0.37834838,"about_ca_system_score_codex":0.0000065475247,"about_ca_system_score_gemma":0.00003535348,"threshold_uncertainty_score":0.66979355},"labels":[],"label_agreement":null},{"id":"W3087468879","doi":"10.1101/2020.09.20.305425","title":"Ligand Modulation of the Conformational Dynamics of the A <sub>2A</sub> Adenosine Receptor Revealed by Single-Molecule Fluorescence","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Los Alamos National Laboratory; Laboratory Directed Research and Development; Natural Sciences and Engineering Research Council of Canada; National Nuclear Security Administration; U.S. Department of Energy","keywords":"Chemistry; Förster resonance energy transfer; Ligand (biochemistry); G protein-coupled receptor; Biophysics; Adenosine receptor; Transmembrane domain; Stereochemistry; Crystallography; Fluorescence; Receptor; Agonist; Biochemistry","score_opus":0.008113166710543929,"score_gpt":0.18909917741748503,"score_spread":0.1809860107069411,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3087468879","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916118,0.00044440912,0.0055573303,0.00044816855,0.0006114591,0.0006373281,0.0006634909,0.000020499261,0.0000055222995],"genre_scores_gemma":[0.9983516,0.00012729249,0.0011177461,0.0001293007,0.0001720031,0.000031872692,0.000009702874,0.00005604805,0.000004483266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980698,0.00014272612,0.00062693964,0.0004893921,0.00042793015,0.00024316777],"domain_scores_gemma":[0.99764246,0.000017811375,0.00088148704,0.0008514191,0.0005168633,0.00008998016],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026738277,0.00033148724,0.0003573695,0.00004190385,0.00011829802,0.000047298163,0.00072291977,0.00045076228,0.000010097921],"category_scores_gemma":[0.00028205544,0.00026054145,0.00024668497,0.0002880142,0.00016496443,0.000010867246,0.000594052,0.00034938453,0.0000021303772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042200885,0.000064415326,0.00084417744,0.00021123343,0.00008652728,2.2125872e-7,0.000009895769,0.00024202156,0.9975581,0.00031045664,0.00062677125,0.000003975846],"study_design_scores_gemma":[0.00030280004,0.00006613176,0.0035827148,0.00030626636,0.000053654054,2.0288969e-8,0.000004048853,0.0025875294,0.9925619,0.0000055275264,0.00025831177,0.00027111234],"about_ca_topic_score_codex":0.000010607258,"about_ca_topic_score_gemma":0.0000021547935,"teacher_disagreement_score":0.0067397584,"about_ca_system_score_codex":0.00006977994,"about_ca_system_score_gemma":0.00039705486,"threshold_uncertainty_score":0.9999847},"labels":[],"label_agreement":null},{"id":"W3090462036","doi":"10.1038/s41592-020-0953-2","title":"An optimized acetylcholine sensor for monitoring in vivo cholinergic activity","year":2020,"lang":"en","type":"article","venue":"Nature Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":446,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; Western University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Canadian Institutes of Health Research","keywords":"Acetylcholine; Cholinergic; Intracellular; Biophysics; Acetylcholine receptor; Neuroscience; In vivo; Chemistry; Biology; Cell biology; Biochemistry; Receptor; Pharmacology","score_opus":0.02894597706279966,"score_gpt":0.3892585888557035,"score_spread":0.36031261179290386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3090462036","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6202779,0.00057603,0.3780725,0.00027486915,0.00041800964,0.0002554043,0.000018854706,0.0000229281,0.00008352763],"genre_scores_gemma":[0.46636602,0.000053436564,0.53224295,0.00024656198,0.0009584164,0.000027253085,0.000014068266,0.000026452833,0.00006482865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987921,0.00026173453,0.0001629366,0.00044878048,0.00009215232,0.00024229074],"domain_scores_gemma":[0.9994428,0.00004923413,0.000068992216,0.00023071498,0.0000737151,0.00013455679],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006998216,0.0001714435,0.00024797782,0.000035312096,0.00005052751,0.000027186854,0.00019366283,0.0005080934,0.00003086598],"category_scores_gemma":[0.00039959073,0.00015769285,0.000121370256,0.00013480603,0.0000133331005,0.0000074308077,0.00004652843,0.00037868985,4.039294e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039430123,0.000033878172,0.00008134865,0.000018062563,0.000017911078,9.327052e-7,0.00005877073,0.0026812302,0.98658913,0.000019701785,0.00007364076,0.010031071],"study_design_scores_gemma":[0.0011275352,0.000196469,0.00005698906,0.000007492785,0.000011348617,0.0000015198999,0.00004703519,0.007394239,0.9790866,0.000034127213,0.0118525885,0.00018409842],"about_ca_topic_score_codex":0.000004357147,"about_ca_topic_score_gemma":0.0000011021511,"teacher_disagreement_score":0.15417044,"about_ca_system_score_codex":0.000012828231,"about_ca_system_score_gemma":0.00003177364,"threshold_uncertainty_score":0.64305276},"labels":[],"label_agreement":null},{"id":"W3091977712","doi":"10.1016/j.neubiorev.2020.09.028","title":"Trace Amine-Associated Receptor 1 (TAAR1): A new drug target for psychiatry?","year":2020,"lang":"en","type":"review","venue":"Neuroscience & Biobehavioral Reviews","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Health and Medical Research Council","keywords":"Neuroscience; Psychosis; Schizophrenia (object-oriented programming); Antipsychotic; Bioinformatics; Medicine; Psychiatry; Pharmacology; Psychology; Biology","score_opus":0.0824585365725937,"score_gpt":0.36638119456114676,"score_spread":0.2839226579885531,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3091977712","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007038891,0.9915617,0.0016545996,0.000032846463,0.0029054591,0.003352818,0.00034564704,0.00005486982,0.00002166289],"genre_scores_gemma":[0.0000065880527,0.98824775,0.0071666115,0.00049866,0.0008937822,0.00051287975,0.00059397204,0.00014987664,0.0019299042],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954219,0.00027893457,0.0013652822,0.0017346473,0.0003892707,0.00080995396],"domain_scores_gemma":[0.9974303,0.0000034235552,0.0011425263,0.000767729,0.00008976888,0.0005662442],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00076158263,0.00096081226,0.002247741,0.00011008331,0.00026714706,0.00019231367,0.0013120973,0.00053915643,0.00016634566],"category_scores_gemma":[0.0006065637,0.00077279506,0.001771654,0.00070071314,0.00011290847,0.000018208462,0.00022967278,0.00046864751,0.00009170622],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009575692,0.00011712721,0.0000044282865,0.001033605,9.4068577e-7,0.0000018961848,0.000012293108,2.5843212e-7,0.01180118,0.000021178334,0.055961043,0.9310365],"study_design_scores_gemma":[0.0002655964,0.000739366,7.991269e-7,0.0018972288,0.00038070735,0.0000140171,0.0000066394396,0.000005148642,0.00024855294,0.000015893007,0.99563557,0.00079045515],"about_ca_topic_score_codex":0.000015530275,"about_ca_topic_score_gemma":0.00001333814,"teacher_disagreement_score":0.93967456,"about_ca_system_score_codex":0.00007341369,"about_ca_system_score_gemma":0.0009863827,"threshold_uncertainty_score":0.9994723},"labels":[],"label_agreement":null},{"id":"W3092386371","doi":"10.1016/j.isci.2020.101643","title":"Location Bias as Emerging Paradigm in GPCR Biology and Drug Discovery","year":2020,"lang":"en","type":"review","venue":"iScience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Drug discovery; Paradigm shift; Computational biology; Data science; Biology; Computer science; Bioinformatics; Physics","score_opus":0.0334747271003602,"score_gpt":0.32659130204775977,"score_spread":0.29311657494739957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092386371","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013386486,0.99602026,0.0019880505,0.00007646494,0.00022026985,0.00020463613,0.000006254458,0.0000056004865,0.00013983688],"genre_scores_gemma":[0.011077168,0.9882718,0.00016825141,0.000080181366,0.00014382417,0.000027803895,0.000054406108,0.000014999902,0.00016158848],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99875396,0.00010793135,0.00027181391,0.00057496823,0.00007874499,0.00021260361],"domain_scores_gemma":[0.99956423,0.000023968088,0.00014283412,0.00019182032,0.000013117507,0.00006404125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029848417,0.00019607597,0.00040934305,0.00007249427,0.000059699203,0.00006240901,0.00026789514,0.0001470427,0.000009045299],"category_scores_gemma":[0.0001247891,0.00015752061,0.00008058907,0.00028532473,0.00009443866,0.000009050768,0.00016705522,0.00012784635,0.000013026147],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000036258107,0.000015048252,0.000034106986,0.0009926956,0.000015395015,0.0000076282654,0.000098176475,0.000010919365,0.0055326805,0.0026187024,0.000087486216,0.99058354],"study_design_scores_gemma":[0.000059990056,0.00006461932,0.0000024529209,0.0008944381,0.000022536637,0.000022744807,0.000032650725,0.00003203191,0.0011550442,0.00042908834,0.9970464,0.00023801849],"about_ca_topic_score_codex":0.00004713362,"about_ca_topic_score_gemma":0.00001819269,"teacher_disagreement_score":0.9969589,"about_ca_system_score_codex":0.000017216194,"about_ca_system_score_gemma":0.00023712114,"threshold_uncertainty_score":0.64235044},"labels":[],"label_agreement":null},{"id":"W3092476911","doi":"10.1038/s41586-020-2793-8","title":"Amygdala inhibitory neurons as loci for translation in emotional memories","year":2020,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health","keywords":"Amygdala; Inhibitory postsynaptic potential; Neuroscience; Memory consolidation; Stimulus (psychology); Neuron; Biology; Optogenetics; Psychology; Cognitive psychology; Hippocampus","score_opus":0.012489000106180247,"score_gpt":0.25629132061149706,"score_spread":0.2438023205053168,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3092476911","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9859751,0.002136102,0.0062749367,0.004243524,0.0003694869,0.00029607833,0.00004303686,0.000016894117,0.0006448277],"genre_scores_gemma":[0.99562776,0.000030137368,0.0014484854,0.001979439,0.00057230936,0.000010567941,0.00022760492,0.000012442639,0.000091242495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99952674,0.00001750875,0.000088546636,0.00018939434,0.00008000429,0.00009781482],"domain_scores_gemma":[0.99983853,0.000009779853,0.000022719947,0.00005379132,0.000035277128,0.000039888044],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000053032065,0.000072197334,0.00006728369,0.000014841363,0.000034214183,0.0000111122245,0.0000630656,0.0005003173,0.000043938653],"category_scores_gemma":[0.00007324156,0.00007090496,0.000059402315,0.000053342086,0.000011966255,0.0000032162106,0.000011533776,0.00030873387,0.000002560457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009106097,0.000013566345,0.000096001764,0.000020463725,0.000007893616,0.0000012880201,0.0001476759,0.00021648392,0.9929627,0.0005669,0.00348753,0.0023884408],"study_design_scores_gemma":[0.0006585272,0.00024078084,0.0002513969,0.000008601676,0.000006552055,0.00000278819,0.000107893815,0.0005210194,0.8707101,0.0006400239,0.12671717,0.00013518338],"about_ca_topic_score_codex":8.755121e-7,"about_ca_topic_score_gemma":0.000005830213,"teacher_disagreement_score":0.12322963,"about_ca_system_score_codex":0.0000041923536,"about_ca_system_score_gemma":0.000038821676,"threshold_uncertainty_score":0.38589054},"labels":[],"label_agreement":null},{"id":"W3093267478","doi":"10.1038/s41598-020-73674-0","title":"Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells","year":2020,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Horizon 2020; Canadian Institutes of Health Research; Knud Højgaards Fond; Novo Nordisk Fonden; Oticon Fonden; Novo Nordisk; H. Lundbeck A/S; Lundbeckfonden; Carlsbergfondet; European Commission; Toyota Foundation; Sundhed og Sygdom, Det Frie Forskningsråd","keywords":"CRISPR; Internalization; HEK 293 cells; Computational biology; Biology; Bioinformatics; Chemistry; Receptor; Genetics; Gene","score_opus":0.034562993767949704,"score_gpt":0.27596086787662444,"score_spread":0.24139787410867475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3093267478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99405354,0.00084202335,0.0030359495,0.000061591134,0.001683557,0.00028495243,0.0000020600837,0.000005983672,0.00003033194],"genre_scores_gemma":[0.99884933,0.000050552822,0.0007962503,0.00003985759,0.00013407637,0.000008155512,0.00003009854,0.000011734369,0.00007993718],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988255,0.000051609913,0.00035430543,0.00046161943,0.00016379262,0.00014317206],"domain_scores_gemma":[0.99938214,0.00001267576,0.00023964317,0.00019767387,0.000097542325,0.000070317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065342156,0.0001043434,0.00013157229,0.00004178644,0.00012316775,0.00009716925,0.000068608984,0.00006226148,0.000026686046],"category_scores_gemma":[0.00019774509,0.000080422906,0.000033510063,0.00016589795,0.00010292239,0.000009249955,0.0001239305,0.00006415363,2.5077912e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015863268,0.0000119961915,0.004469451,0.000033089873,0.000008942142,0.000008092787,0.00080693467,0.0002501164,0.99304116,0.00001380636,0.0003135133,0.0010270649],"study_design_scores_gemma":[0.00010651479,0.000058898953,0.00013983165,0.00006926183,0.000011302173,0.000024462237,0.00068714627,0.0024689406,0.9903003,0.00028734648,0.0057453327,0.000100657686],"about_ca_topic_score_codex":0.000030605406,"about_ca_topic_score_gemma":0.0000343258,"teacher_disagreement_score":0.0054318192,"about_ca_system_score_codex":0.000008749909,"about_ca_system_score_gemma":0.00003836731,"threshold_uncertainty_score":0.3279551},"labels":[],"label_agreement":null},{"id":"W3094071809","doi":"10.1101/2020.10.25.354209","title":"Drug self-administration in head-restrained mice for simultaneous multiphoton imaging","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Langara College","funders":"","keywords":"Neuroscience; Addiction; Limiting; Biological neural network; Neuroplasticity; Drug; Psychology; Self-administration; Medicine; Computer science; Pharmacology","score_opus":0.009725615815595426,"score_gpt":0.2359949076278049,"score_spread":0.22626929181220948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094071809","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98415554,0.0007767322,0.0120184235,0.00035928708,0.00079267833,0.0014435151,0.00028472114,0.00016325853,0.0000058528612],"genre_scores_gemma":[0.9732147,0.00013290669,0.025224064,0.0003178754,0.0007021676,0.00024780352,0.000009788005,0.00014446641,0.00000626622],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973523,0.00010576353,0.0005841531,0.001217576,0.00021662757,0.00052357087],"domain_scores_gemma":[0.99848354,0.00006152934,0.00033035956,0.0006091227,0.00028938797,0.00022606473],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000398024,0.00053498393,0.00045799438,0.0001166066,0.000110155845,0.00016749316,0.00045349562,0.00043365057,0.000013815769],"category_scores_gemma":[0.00035225475,0.00063114386,0.000212385,0.00016569332,0.000040280065,0.00001023036,0.00024754112,0.00042108106,0.00000932294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001528057,0.000119310265,0.0004955013,0.00031271816,0.000066870365,0.000049616545,0.000018849214,0.00048514619,0.998073,0.00007626623,0.00014561648,0.000004294779],"study_design_scores_gemma":[0.0009543701,0.00009854927,0.0004548144,0.000160099,0.00005634269,4.509695e-8,0.000010284789,0.014385032,0.97604394,0.0000048412608,0.007108281,0.0007233756],"about_ca_topic_score_codex":0.00004877758,"about_ca_topic_score_gemma":0.000027129474,"teacher_disagreement_score":0.022029039,"about_ca_system_score_codex":0.00009759506,"about_ca_system_score_gemma":0.00066354004,"threshold_uncertainty_score":0.999614},"labels":[],"label_agreement":null},{"id":"W3094232112","doi":"10.1101/2020.10.21.349142","title":"Absence of postsynaptic activity on developing neurons alters gene expression profiles without preventing the refinement of inputs","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Postsynaptic potential; Neuroscience; Excitatory postsynaptic potential; Synaptic plasticity; Synapse; Biology; Neurotransmission; Premovement neuronal activity; Neuron; Inhibitory postsynaptic potential; Synaptic augmentation; Gene expression; Gene; Genetics; Receptor","score_opus":0.019127552467664233,"score_gpt":0.23917379327616187,"score_spread":0.22004624080849763,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094232112","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987162,0.00023363174,0.011337782,0.00019617136,0.00036201245,0.0006064375,0.00007050859,0.000027747856,0.0000037307527],"genre_scores_gemma":[0.98648804,0.00017888071,0.01289769,0.00011964135,0.00017760067,0.00007154032,0.0000010631813,0.00006380048,0.0000017316894],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99800724,0.00017276747,0.00046916955,0.0007320226,0.00032800078,0.0002908075],"domain_scores_gemma":[0.99806005,0.000029392224,0.000761718,0.00081975135,0.00023958235,0.000089526824],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00039821607,0.00036314092,0.00041682247,0.000069657355,0.00010727778,0.00003316499,0.00053201726,0.0002700782,0.00000833709],"category_scores_gemma":[0.00022196698,0.00030214223,0.00015960791,0.00014706825,0.000087077395,0.0000065648123,0.0007120838,0.0003512018,0.0000016947729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008261541,0.000057773537,0.0013146308,0.00035922142,0.00009815362,0.0000028152194,0.000012130301,0.00020992546,0.99773,0.000100072226,0.000026886215,0.0000057760044],"study_design_scores_gemma":[0.00019711535,0.00016698775,0.0074977283,0.0006379413,0.00003837681,1.555897e-8,0.0000032839846,0.0001945185,0.9908253,0.0000018779975,0.00014078767,0.0002960713],"about_ca_topic_score_codex":0.000016879576,"about_ca_topic_score_gemma":8.972992e-7,"teacher_disagreement_score":0.0069047045,"about_ca_system_score_codex":0.000034539346,"about_ca_system_score_gemma":0.00043043372,"threshold_uncertainty_score":0.9999431},"labels":[],"label_agreement":null},{"id":"W3094575136","doi":"10.1139/cjpp-2020-0347","title":"Involvement of G proteins and Rho kinase in α<sub>1</sub>-adrenoceptor mediated contractions of the rat portal vein","year":2020,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Phenylephrine; Prazosin; Tonic (physiology); Internal medicine; Antagonist; Endocrinology; Chemistry; Agonist; Medicine; Receptor","score_opus":0.010481461384488338,"score_gpt":0.22543781512261876,"score_spread":0.21495635373813043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3094575136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974988,0.001310298,0.000021400312,0.0006835215,0.0002873188,0.00014797192,0.000037982547,5.0113357e-7,0.000012198816],"genre_scores_gemma":[0.99887615,0.00027911508,0.000029724593,0.000657054,0.00013488297,0.0000043188757,0.000010004378,0.000006113386,0.0000026175583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999273,0.00013465858,0.0002919757,0.00011516158,0.000037187303,0.00014798852],"domain_scores_gemma":[0.99939907,0.000025723377,0.00024267202,0.000046092595,0.00008931965,0.00019713838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014011118,0.00008607577,0.00022115359,0.000053804677,0.000047734102,0.0000021085293,0.000103655315,0.00011610265,0.00023353755],"category_scores_gemma":[0.000051235154,0.00006797452,0.0000541582,0.0000717458,0.0002093926,0.0000056819445,0.000023539073,0.0001792162,2.5247385e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010969556,0.000021061676,0.0009733823,0.0000389181,0.00007164837,0.000009413649,0.00018500816,0.00006552204,0.99757373,0.00003429197,0.0007194756,0.0001978434],"study_design_scores_gemma":[0.00090267044,0.0005151737,0.0021893785,0.000012884499,0.000033652814,0.000016514861,0.00011808171,0.00003822659,0.99467605,0.00008698432,0.0013496664,0.000060703802],"about_ca_topic_score_codex":0.00013084697,"about_ca_topic_score_gemma":0.0010420942,"teacher_disagreement_score":0.0028976768,"about_ca_system_score_codex":0.0000083771965,"about_ca_system_score_gemma":0.0004349188,"threshold_uncertainty_score":0.27719206},"labels":[],"label_agreement":null},{"id":"W3099092309","doi":"10.1101/2020.11.12.380451","title":"Differential dopamine receptor-dependent sensitivity improves action selection in the basal ganglia","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Action selection; Basal ganglia; Sensitivity (control systems); Neuroscience; Dopaminergic; Action (physics); Selection (genetic algorithm); Weighting; Biology; Dopamine; Computer science; Artificial intelligence; Physics; Perception; Central nervous system","score_opus":0.015384740936189972,"score_gpt":0.22856678545831907,"score_spread":0.2131820445221291,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3099092309","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857086,0.00016448829,0.011765475,0.0003159614,0.0012496813,0.0006316153,0.00008597044,0.000074076444,0.0000041608187],"genre_scores_gemma":[0.9965273,0.00022319482,0.0008727382,0.0003260352,0.0018496665,0.000102653365,0.000004705248,0.00008702581,0.000006658806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973625,0.00043684943,0.0004026062,0.0010037489,0.00036702259,0.0004272935],"domain_scores_gemma":[0.9988516,0.000025847565,0.00029507987,0.00050333096,0.00019630839,0.0001278342],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00052647915,0.00047975688,0.00037562498,0.00010384385,0.00014727947,0.00019858808,0.00032479028,0.00063694996,0.00005614926],"category_scores_gemma":[0.00016483176,0.00043258056,0.00018554206,0.00022543281,0.000049806444,0.000012378065,0.00033325868,0.00079582963,0.00001845012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001131071,0.00010238281,0.0008471513,0.00010101818,0.00008003207,0.000013633216,0.000009135691,0.00006556793,0.99825275,0.000058762143,0.00034613133,0.000010350292],"study_design_scores_gemma":[0.000418212,0.0001469321,0.010887674,0.00006114161,0.00005420781,4.223243e-8,0.00001288473,0.00072468456,0.9863949,0.000004779142,0.000801376,0.00049318565],"about_ca_topic_score_codex":0.00010101113,"about_ca_topic_score_gemma":0.000039399758,"teacher_disagreement_score":0.011857848,"about_ca_system_score_codex":0.000093185896,"about_ca_system_score_gemma":0.0002501253,"threshold_uncertainty_score":0.9998126},"labels":[],"label_agreement":null},{"id":"W309917894","doi":"10.1016/j.ymeth.2015.05.003","title":"Designing BRET-based conformational biosensors for G protein-coupled receptors","year":2015,"lang":"en","type":"article","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Québec Consortium for Drug Discovery; McGill University","keywords":"Allosteric regulation; Biosensor; Receptor; G protein-coupled receptor; Intracellular; Signal transduction; Chemistry; Cell signaling; Computational biology; Drug discovery; Cell; Cell biology; Luciferase; Signaling proteins; Biophysics; Biochemistry; Nanotechnology; Biology; Materials science; Transfection; Gene","score_opus":0.054955660731832695,"score_gpt":0.3513174045804909,"score_spread":0.2963617438486582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W309917894","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.05441261,0.00014105611,0.9441838,0.00009095894,0.00034132402,0.00044611187,0.000007469037,0.00002322812,0.00035339306],"genre_scores_gemma":[0.07618087,0.000001651785,0.92225194,0.00023581018,0.00023441997,0.00013427179,0.00014903415,0.000027056698,0.0007849437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990183,0.00018419458,0.0002255237,0.0002230817,0.00012526216,0.00022364222],"domain_scores_gemma":[0.99935454,0.000037965852,0.00010347517,0.00017263908,0.00020756236,0.00012384183],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017389402,0.00013728008,0.00014916815,0.0000478604,0.00008277308,0.000033139724,0.00012949038,0.00015058619,0.00005769024],"category_scores_gemma":[0.00052413094,0.00012503979,0.000105318126,0.00007212238,0.000032293297,0.0000048798265,0.00002648538,0.00005641051,0.0000057063025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012578351,0.00001472585,0.000011702287,0.000015003128,0.00002146401,1.7902259e-7,0.000048143025,0.0005415115,0.9931062,0.00042745544,0.0010078214,0.0046800496],"study_design_scores_gemma":[0.000785246,0.00029969792,0.0000018328774,0.000010952506,0.000010032066,0.000001929334,0.00013100164,0.008847319,0.9291273,0.00074458524,0.059867844,0.00017228874],"about_ca_topic_score_codex":0.000006181615,"about_ca_topic_score_gemma":7.8297353e-7,"teacher_disagreement_score":0.06397889,"about_ca_system_score_codex":0.000019682637,"about_ca_system_score_gemma":0.00016412878,"threshold_uncertainty_score":0.5098975},"labels":[],"label_agreement":null},{"id":"W3099545120","doi":"10.1016/s0006-291x(03)00709-5","title":"Novel human G-protein-coupled receptors","year":2003,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto; Canada Research Chairs","funders":"","keywords":"G protein-coupled receptor; Gene; Biology; Receptor; Computational biology; Signal transduction; GenBank; Genetics","score_opus":0.07777662915191999,"score_gpt":0.3629997789500973,"score_spread":0.2852231497981773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3099545120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99473935,0.0008823521,0.00091529795,0.0005414006,0.000029852225,0.00029697287,0.000012413822,0.000020351736,0.0025620013],"genre_scores_gemma":[0.9923924,0.00025738543,0.005969077,0.00005144577,0.00010543154,0.000091900874,0.0001405947,0.000020180489,0.00097155897],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986079,0.00018017065,0.00019606647,0.00036663603,0.00028036395,0.00036889166],"domain_scores_gemma":[0.99848765,0.000063430365,0.00003553022,0.00095120625,0.00023885541,0.000223323],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057935936,0.00013849679,0.00013794313,0.000052440188,0.00051541755,0.00006278789,0.0005630971,0.00017142067,0.0000836863],"category_scores_gemma":[0.00041686004,0.00012088171,0.000075736396,0.00024378432,0.0005835298,0.0000051062366,0.00036889277,0.00035474563,0.000024341674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012062363,0.00023600787,0.000012438785,0.000008882236,0.000018472083,1.3191631e-7,0.0000142778745,1.1228118e-7,0.96688753,0.031756308,0.0007498497,0.00030390776],"study_design_scores_gemma":[0.00030629753,0.00019914005,0.000033026125,0.000019048883,0.000005243538,0.0000029834675,0.00008637878,0.00007153568,0.95129436,0.0018339097,0.045976803,0.00017126501],"about_ca_topic_score_codex":0.00005396229,"about_ca_topic_score_gemma":0.000005571972,"teacher_disagreement_score":0.045226954,"about_ca_system_score_codex":0.000018546387,"about_ca_system_score_gemma":0.00006430507,"threshold_uncertainty_score":0.49294132},"labels":[],"label_agreement":null},{"id":"W3101130800","doi":"10.1016/j.csbj.2020.10.026","title":"Allosteric inhibition explained through conformational ensembles sampling distinct “mixed” states","year":2020,"lang":"en","type":"review","venue":"Computational and Structural Biotechnology Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Allosteric regulation; Allosteric enzyme; Chemistry; Protein dynamics; Molecular dynamics; Protein kinase A; Biophysics; Computational biology; Enzyme; Biochemistry; Biology; Computational chemistry","score_opus":0.03011609963885143,"score_gpt":0.2956940952113686,"score_spread":0.26557799557251716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3101130800","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00725891,0.92869043,0.06264414,0.00042526153,0.00044073875,0.00025161862,0.00023411907,0.00003966968,0.000015131501],"genre_scores_gemma":[0.0065145683,0.9756124,0.014477621,0.00014542439,0.00051654386,0.00001220526,0.002671642,0.000034925022,0.000014681082],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983638,0.00009377771,0.00068681396,0.0003853075,0.00020315095,0.0002671836],"domain_scores_gemma":[0.999103,0.00005863437,0.00051676284,0.00009728351,0.00012193346,0.00010239578],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012134496,0.00040026408,0.000679418,0.00011762552,0.0004216997,0.00013794037,0.00019371798,0.0005750357,0.00005988764],"category_scores_gemma":[0.00006591029,0.00031016505,0.00024201194,0.00013316942,0.00016918017,0.000021547032,0.00020225729,0.0005557874,0.000007708665],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005133813,0.000010330787,0.0000033922734,0.001036868,0.00046534557,0.00004549679,0.00009580015,0.0005284432,0.0013245941,0.0040669804,0.00061161316,0.9917598],"study_design_scores_gemma":[0.0006543934,0.00046406814,0.00001354317,0.0012161646,0.00021547748,0.008509542,0.00017238675,0.0011478175,0.0009339038,0.027403127,0.95849955,0.00077003194],"about_ca_topic_score_codex":0.00000109734,"about_ca_topic_score_gemma":9.934653e-7,"teacher_disagreement_score":0.99098974,"about_ca_system_score_codex":0.000038776303,"about_ca_system_score_gemma":0.00018922072,"threshold_uncertainty_score":0.99993503},"labels":[],"label_agreement":null},{"id":"W3105127887","doi":"10.1007/978-3-030-58677-5_8","title":"Sex-Specific Differences in β-Adrenoceptor Signal Transduction in Heart Failure Due to Volume-Overload","year":2020,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Adenylyl cyclase; Internal medicine; Endocrinology; Pressure overload; Heart failure; Volume overload; Muscle hypertrophy; Epinephrine; Medicine; Biology; Receptor; Cardiac hypertrophy","score_opus":0.013927344355294895,"score_gpt":0.20467032153415127,"score_spread":0.19074297717885638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3105127887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.611918,0.014328215,0.10781701,0.019067118,0.0059443894,0.009878699,0.0012159924,0.00046767146,0.22936296],"genre_scores_gemma":[0.8100943,0.0003655541,0.0047493973,0.00083170866,0.0015549439,0.00006571416,0.0004939475,0.00015493852,0.1816895],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9981099,0.000037412676,0.00045332685,0.0008547675,0.0002444726,0.00030011422],"domain_scores_gemma":[0.99948245,0.000008805204,0.0000683574,0.00024097756,0.00004207109,0.00015736242],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013444519,0.00041448517,0.0005559672,0.00015831544,0.00003894703,0.000051235405,0.00023280071,0.00061909,0.0147136655],"category_scores_gemma":[0.000005386593,0.00040785482,0.00018572334,0.000060503506,0.000036090474,0.0000051828515,0.0000688876,0.00037195723,0.00012804403],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018127832,0.00004685425,0.00027528286,0.00005051483,0.000052883253,0.00002980441,0.00023779311,0.000060620365,0.97265506,0.00260736,0.017509658,0.0062928945],"study_design_scores_gemma":[0.0006675787,0.0008621467,0.00015039749,0.00016466116,0.000014029506,0.00002332119,0.0002353488,0.00005065051,0.3419698,0.0013456941,0.6535091,0.001007307],"about_ca_topic_score_codex":0.00004915431,"about_ca_topic_score_gemma":0.00039042166,"teacher_disagreement_score":0.63599944,"about_ca_system_score_codex":0.00004602765,"about_ca_system_score_gemma":0.00007546149,"threshold_uncertainty_score":0.99983734},"labels":[],"label_agreement":null},{"id":"W3106178930","doi":"10.1038/s41467-020-19510-5","title":"Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging","year":2020,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Key Research and Development Program of China; Australian Research Council; Peking University; National Natural Science Foundation of China","keywords":"G protein-coupled receptor; Receptor; Cannabinoid receptor; Cannabinoid; Agonist; Cell biology; Intracellular; Cannabinoid Receptor Agonists; G protein; Biology; Neuroscience; Chemistry; Signal transduction; Biophysics; Biochemistry","score_opus":0.009015859324167996,"score_gpt":0.24825749063645278,"score_spread":0.2392416313122848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3106178930","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83476377,0.038981076,0.01576039,0.10541134,0.00075531687,0.0016516737,0.0014597627,0.00024077736,0.0009758854],"genre_scores_gemma":[0.9913395,0.0009978544,0.0024444547,0.0009630381,0.000079096106,0.000030263109,0.004064668,0.000020578627,0.000060519076],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990056,0.00018598397,0.00022014634,0.00027942972,0.00010945947,0.00019936592],"domain_scores_gemma":[0.9990304,0.00001864019,0.00006761917,0.000657382,0.00012850131,0.00009744533],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001515599,0.00012823213,0.00011981735,0.000019919396,0.00018104303,0.000030966225,0.0006323091,0.00019852327,0.00005092038],"category_scores_gemma":[0.00041307954,0.0001368219,0.000048178303,0.00027608103,0.00006399528,0.00001027796,0.0002696084,0.0005429673,0.000015379108],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024118284,0.000041795432,0.0021231817,0.000004695575,0.0000053693857,2.9030937e-7,0.000060684695,0.000008875333,0.9322243,0.0003730176,0.06460235,0.0005313185],"study_design_scores_gemma":[0.0010164101,0.000105595995,0.0023985065,0.000032666085,0.00002270227,0.0000055439523,0.00023548778,0.004508044,0.35356447,0.000040587565,0.637637,0.00043299783],"about_ca_topic_score_codex":0.000046756446,"about_ca_topic_score_gemma":0.0000641386,"teacher_disagreement_score":0.57865983,"about_ca_system_score_codex":0.000041688967,"about_ca_system_score_gemma":0.000069461836,"threshold_uncertainty_score":0.5579435},"labels":[],"label_agreement":null},{"id":"W3106586359","doi":"","title":"9th GPCR Retreat (Canada) - Regulation of the dopamine D3 receptor and adenylyl cyclase type 5 signalosome by a sodium orthovanadate-sensitive pathway","year":2008,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Adenylyl cyclase; Receptor; Chemistry; ADCY9; Cell biology; Internal medicine; Endocrinology; Biology; Biochemistry; Medicine","score_opus":0.006360674630220903,"score_gpt":0.1752401261388612,"score_spread":0.16887945150864028,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3106586359","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974768,0.00045634655,0.00052878587,0.00017950282,0.00022114073,0.00017524179,0.00007623422,0.0000070639917,0.0008788899],"genre_scores_gemma":[0.9908009,0.00015005097,0.00048640184,0.00019405934,0.000088969806,0.0000030133504,0.00016136665,0.000018803206,0.008096425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903125,0.00006878709,0.00020962888,0.0002846745,0.00022992185,0.00017571828],"domain_scores_gemma":[0.99939466,0.00001674536,0.00011130041,0.00025090552,0.00014655401,0.00007986842],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009116814,0.00015217005,0.00016292778,0.000017896406,0.0001422596,0.000007718032,0.0000952488,0.00011838712,0.00017042545],"category_scores_gemma":[0.000059111215,0.00010873252,0.000047496258,0.0001101773,0.00008836978,0.000005157967,0.00007206979,0.00007344473,0.0000012448069],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079619465,0.000018415762,0.0004502301,0.0000074039594,0.00003019445,0.0000023543312,0.000019846428,0.000013643656,0.9852562,0.000077424906,0.013731418,0.00031322445],"study_design_scores_gemma":[0.00030003974,0.00016727064,0.00059128454,0.000012851357,0.0000109228395,0.000021280672,0.00007141429,0.00009820058,0.97616506,0.000017983863,0.02239475,0.00014892842],"about_ca_topic_score_codex":0.0066123535,"about_ca_topic_score_gemma":0.010435636,"teacher_disagreement_score":0.009091153,"about_ca_system_score_codex":0.000022335846,"about_ca_system_score_gemma":0.0002351661,"threshold_uncertainty_score":0.9995945},"labels":[],"label_agreement":null},{"id":"W3106788405","doi":"","title":"8th GPCR Retreat (Canada) - Structural determinants of human D1 and D5 dopaminergic receptors underlying PKC-mediated subtype-specific regulation","year":2007,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Dopaminergic; G protein-coupled receptor; Receptor; Biology; Neuroscience; Dopamine; Genetics","score_opus":0.01906655138315567,"score_gpt":0.2578587033499249,"score_spread":0.23879215196676923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3106788405","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99794906,0.00032352103,0.0006629778,0.000010399945,0.00022790467,0.000112900496,0.000005857574,0.000010231088,0.00069715723],"genre_scores_gemma":[0.9982638,0.0000618608,0.0006734843,0.00002677963,0.00009593789,0.0000012670523,0.00013323074,0.000021358028,0.0007223137],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888724,0.00002968922,0.00033182796,0.00030566027,0.00019670332,0.0002488518],"domain_scores_gemma":[0.9994509,0.000020628137,0.00014522,0.00020314194,0.00008280397,0.00009728562],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021971329,0.00016375638,0.00018595315,0.000056218898,0.00012369188,0.0000171615,0.000098332406,0.00015323835,0.00021132908],"category_scores_gemma":[0.000023268352,0.00014308123,0.00004182058,0.00010049771,0.00005719428,0.0000066254092,0.00004611182,0.00006444511,5.778329e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047023514,0.000005579124,0.013681705,0.000014034012,0.000013594622,0.0000030305268,0.000026318794,0.000008436259,0.981531,0.00021604371,0.0002425347,0.0042106546],"study_design_scores_gemma":[0.00044587124,0.00026439992,0.030684613,0.00001982939,0.000010062376,0.000012583358,0.00025907933,0.00015138158,0.966815,0.00013929002,0.0009740208,0.00022388835],"about_ca_topic_score_codex":0.0038743108,"about_ca_topic_score_gemma":0.032179207,"teacher_disagreement_score":0.028304897,"about_ca_system_score_codex":0.00003201796,"about_ca_system_score_gemma":0.000052682513,"threshold_uncertainty_score":0.985481},"labels":[],"label_agreement":null},{"id":"W3107715002","doi":"10.1093/ehjci/ehaa946.2570","title":"Chromogranin B is associated with impaired coronary collateralization and heart failure in patients with stable angina and chronic total occlusion","year":2020,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Collateralization; Medicine; Cardiology; Internal medicine; Angina; Heart failure; Coronary artery disease; Canadian Cardiovascular Society; Myocardial infarction","score_opus":0.007223836512376743,"score_gpt":0.19753856265434086,"score_spread":0.19031472614196412,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3107715002","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990279,0.0002808284,0.00017169415,0.00032743465,0.0000219939,0.00013644769,0.000011297453,0.000007087565,0.000015326728],"genre_scores_gemma":[0.99901146,0.000029127728,0.00039762954,0.00036358033,0.000090396614,4.775331e-7,0.000049593502,0.00002902903,0.000028717373],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992042,0.00014626935,0.00012998405,0.00020203774,0.00013357631,0.00018391937],"domain_scores_gemma":[0.9996826,0.00000379768,0.000064799904,0.00005562416,0.00006130938,0.00013187555],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016429133,0.00012151885,0.00013366525,0.000029043193,0.00014334393,0.000071177165,0.000035610206,0.000039687115,0.000053321593],"category_scores_gemma":[0.000012419683,0.00009466792,0.000019622734,0.00009533851,0.000028022634,0.00001676568,0.000055884866,0.00012037375,0.0000012493118],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004617088,0.00007117611,0.66997546,0.000022361995,0.00007079728,0.00006113544,0.0005898739,0.00038685102,0.32431576,0.000001274524,0.0038176924,0.00022592614],"study_design_scores_gemma":[0.0044393395,0.005063296,0.97297466,0.00020340028,0.000022633192,0.00026733938,0.00009207644,0.0006651633,0.012758086,0.0000017494947,0.0032046686,0.00030759771],"about_ca_topic_score_codex":0.0000020726775,"about_ca_topic_score_gemma":0.000008187791,"teacher_disagreement_score":0.31155768,"about_ca_system_score_codex":0.000021600823,"about_ca_system_score_gemma":0.00004526982,"threshold_uncertainty_score":0.3860446},"labels":[],"label_agreement":null},{"id":"W3108158641","doi":"","title":"Experimental Biology 2008 (USA) - Opposite regulation of human D1-like dopaminergic responsiveness by protein kinase C is shaped by two critical serine residues of the third intracellular loop of human D5 dopaminergic receptor","year":2008,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Dopaminergic; Serine; Intracellular; Protein kinase A; Cell biology; Biology; Phosphorylation; Neuroscience; Dopamine","score_opus":0.015450110921494406,"score_gpt":0.27770521059356185,"score_spread":0.26225509967206745,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108158641","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99667877,0.0018318084,0.00049755623,0.00010787518,0.00009630543,0.0004474787,0.00011804945,0.0000114013565,0.00021077908],"genre_scores_gemma":[0.9948595,0.000048361697,0.00061278587,0.0000660306,0.000080021295,0.000043330376,0.00035549453,0.000038304945,0.003896151],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99778175,0.00034860813,0.00076342234,0.00051791745,0.00027535117,0.0003129651],"domain_scores_gemma":[0.9987148,0.000029787921,0.00034202923,0.0005304132,0.00028584496,0.00009709273],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030240428,0.00030288906,0.00046819972,0.000078590805,0.0001972252,0.00000859003,0.00037354216,0.00027615333,0.0007220858],"category_scores_gemma":[0.000053541567,0.00024083983,0.00019882414,0.00018009129,0.00058575865,0.000014826342,0.00021724426,0.00012854043,0.0000018054833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031877885,0.00032867826,0.00045559113,0.000058337562,0.00005432718,0.0000017258759,0.00009743942,0.000008606043,0.99532324,0.0009640848,0.0023669477,0.000022216567],"study_design_scores_gemma":[0.0010220305,0.0015023445,0.00012880615,0.000064659376,0.000023373866,0.000010987036,0.00015189883,0.0000621397,0.9960993,0.000075149896,0.0005940804,0.0002652372],"about_ca_topic_score_codex":0.00037176328,"about_ca_topic_score_gemma":0.000017368886,"teacher_disagreement_score":0.003685372,"about_ca_system_score_codex":0.000022470387,"about_ca_system_score_gemma":0.00006003311,"threshold_uncertainty_score":0.9821163},"labels":[],"label_agreement":null},{"id":"W3108459786","doi":"10.18100/ijamec.815606","title":"Robust Constrained Drug Dosage Regulation of Acute Inflammation Response Under Disturbances","year":2020,"lang":"en","type":"article","venue":"International Journal of Applied Mathematics Electronics and Computers","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institute for Theoretical Astrophysics","keywords":"Control theory (sociology); Controller (irrigation); Nonlinear system; Parametric statistics; Sliding mode control; Control engineering; Robust control; Computer science; Control (management); Engineering; Mathematics; Biology; Artificial intelligence; Physics","score_opus":0.008295091412058945,"score_gpt":0.21678116381187318,"score_spread":0.20848607239981423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108459786","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6868899,0.00013464883,0.31208906,0.0006284654,0.0000882432,0.00006744026,0.0000049068294,0.0000031404063,0.000094214716],"genre_scores_gemma":[0.97276294,0.00016660022,0.026708683,0.00015289625,0.00017651303,0.0000012878768,0.000014013104,0.000009955939,0.0000071241857],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991662,0.000015936754,0.0003866444,0.000106422034,0.00023643693,0.000088390494],"domain_scores_gemma":[0.9992245,0.00003852894,0.00044980866,0.000058910202,0.00017613314,0.000052131923],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028176754,0.0000957607,0.00016123398,0.000047577927,0.000024623048,0.00003746329,0.00019441488,0.000046539517,0.000009937029],"category_scores_gemma":[0.000014408483,0.000085095424,0.00007089077,0.000042526255,0.000038748716,0.0000094000015,0.00004981533,0.00008374159,3.3884717e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071454217,0.000026732885,0.0000033735325,0.000017081418,0.00035050514,0.0000017586926,0.0005041324,0.0074558617,0.96698964,0.021586696,0.00015955641,0.0021901214],"study_design_scores_gemma":[0.0016441189,0.00053146295,0.0000761598,0.0000759268,0.00009640311,0.000072587856,0.00043211007,0.029830208,0.9487738,0.016696053,0.0015606482,0.00021051418],"about_ca_topic_score_codex":2.8763426e-7,"about_ca_topic_score_gemma":4.339499e-7,"teacher_disagreement_score":0.28587303,"about_ca_system_score_codex":0.000018002016,"about_ca_system_score_gemma":0.000079498335,"threshold_uncertainty_score":0.34700906},"labels":[],"label_agreement":null},{"id":"W3108584164","doi":"","title":"2nd Annual Brain Health Research Day (Canada) - A comprehensive model of sensitization and desensitization of GPCRs by PKC: insight from dopamine D1-like receptors","year":2010,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Desensitization (medicine); G protein-coupled receptor; Receptor; Dopamine; Sensitization; Neuroscience; Pharmacology; Medicine; Psychology; Internal medicine","score_opus":0.02259765208560629,"score_gpt":0.27645274240797957,"score_spread":0.2538550903223733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108584164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9753215,0.00023859012,0.022906909,0.0007519733,0.00017838825,0.00022099042,0.00021516443,0.000004830251,0.00016166212],"genre_scores_gemma":[0.9938243,0.00017515541,0.0043202536,0.00033278772,0.00006718717,0.0000026239475,0.00082714186,0.000021765036,0.0004287833],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986072,0.00020006171,0.00032459636,0.00032469124,0.0003287927,0.00021465987],"domain_scores_gemma":[0.99881876,0.00010178604,0.0001460161,0.00022522642,0.0005829604,0.00012525865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038111472,0.00012817283,0.00022992199,0.000067273264,0.000095121184,0.000011077198,0.00008110402,0.0001597189,0.000048377162],"category_scores_gemma":[0.00013125365,0.00012235391,0.00002782103,0.00013731116,0.000120544464,0.000008459753,0.00008745331,0.00014951553,2.183897e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043962995,0.000028312497,0.00014456866,0.000022335455,0.000025113644,3.103527e-7,0.00022753353,0.0004916906,0.98407936,0.00032048725,0.013107958,0.0015083798],"study_design_scores_gemma":[0.000452779,0.00023425788,0.0001392026,0.000021875316,0.0000052612945,0.0000022388283,0.0006103631,0.016101798,0.97573775,0.00019152096,0.0063560046,0.00014695401],"about_ca_topic_score_codex":0.027849745,"about_ca_topic_score_gemma":0.042790722,"teacher_disagreement_score":0.018586654,"about_ca_system_score_codex":0.000016356165,"about_ca_system_score_gemma":0.00033824303,"threshold_uncertainty_score":0.97862387},"labels":[],"label_agreement":null},{"id":"W3108778136","doi":"10.3390/biom10121634","title":"Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR","year":2020,"lang":"en","type":"article","venue":"Biomolecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Sherbrooke","funders":"","keywords":"Virtual screening; G protein-coupled receptor; Antagonist; Ligand efficiency; Computational biology; Chemistry; Receptor; Ligand (biochemistry); Docking (animal); Pharmacology; Drug discovery; Stereochemistry; Medicine; Biochemistry; Biology","score_opus":0.014106350343973046,"score_gpt":0.23289776212595753,"score_spread":0.2187914117819845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108778136","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.46300334,0.0006034437,0.53401184,0.0009631047,0.00018164594,0.00035650173,0.00073481485,0.000039735132,0.00010557632],"genre_scores_gemma":[0.98108673,0.000026822247,0.01649151,0.0013351934,0.0003665314,0.000011524802,0.0006062565,0.000043034313,0.00003240469],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893916,0.000039717484,0.00025693877,0.00036469346,0.00013627979,0.00026324185],"domain_scores_gemma":[0.99949753,0.000016246106,0.000118863645,0.00018559078,0.000046458033,0.00013528303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000060181155,0.00018548753,0.00020041924,0.000035767993,0.00007738162,0.00003454715,0.00023118278,0.00018245784,0.00008516191],"category_scores_gemma":[0.000061160004,0.00017172442,0.00019437334,0.000097806645,0.000056363744,0.000006208129,0.000056609137,0.000060613624,0.0000012003305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031816072,0.00003500944,0.0001819464,0.000052809522,0.000050648352,0.0000025777374,0.000041499683,0.00012432647,0.9950591,0.0007508196,0.001209602,0.002173547],"study_design_scores_gemma":[0.0008659651,0.0009100574,0.000042025742,0.0000230416,0.000021002412,0.0000022067836,0.00011323757,0.0010705065,0.9809559,0.000034573255,0.015752558,0.00020889875],"about_ca_topic_score_codex":0.000004112364,"about_ca_topic_score_gemma":0.0000015685289,"teacher_disagreement_score":0.5180834,"about_ca_system_score_codex":0.0000026227717,"about_ca_system_score_gemma":0.00008011377,"threshold_uncertainty_score":0.70027184},"labels":[],"label_agreement":null},{"id":"W3108955670","doi":"10.1136/gutjnl-2020-321193","title":"Targeting G protein-coupled receptors for the treatment of chronic pain in the digestive system","year":2020,"lang":"en","type":"review","venue":"Gut","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Institute of Dental and Craniofacial Research; National Institute of Neurological Disorders and Stroke; U.S. Department of Defense; National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health; Crohn's and Colitis Canada","keywords":"G protein-coupled receptor; Chronic pain; Medicine; Nociception; Nociceptor; Opioid; Receptor; Neuroscience; Allosteric modulator; Visceral pain; Pharmacology; Bioinformatics; Agonist; Biology; Internal medicine","score_opus":0.023391114314659647,"score_gpt":0.28024040063499445,"score_spread":0.2568492863203348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3108955670","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000059222923,0.99252564,0.0038560291,0.000030353283,0.00017924691,0.0032871077,0.000035756653,0.000006128996,0.000020547071],"genre_scores_gemma":[0.0011192977,0.99557066,0.0002581634,0.000009396267,0.0007579646,0.0018940829,0.00025587433,0.000040304705,0.00009423592],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99865335,0.00030366937,0.00041008485,0.000317947,0.00010479578,0.00021013939],"domain_scores_gemma":[0.9992246,0.0001432533,0.00029949803,0.000272661,0.000035271674,0.000024723942],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006800496,0.0002670723,0.0006268696,0.000021916596,0.00008396535,0.000019716397,0.00031756793,0.00020040384,0.00000952963],"category_scores_gemma":[0.00009548347,0.00012925174,0.000417582,0.00010585495,0.000027471713,9.412484e-7,0.00002685799,0.000086120315,0.0000030657882],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000222385,0.00006237407,5.293242e-7,0.0047894297,0.00027155344,0.000002980449,0.00020009503,0.000037549264,0.0049519944,0.0001587967,0.00017438123,0.9893281],"study_design_scores_gemma":[0.00019575663,0.0012297438,5.656694e-8,0.0015724469,0.00017285708,0.000002517225,0.00029127844,0.00043415136,0.0009765829,0.0000028869138,0.99497664,0.00014505826],"about_ca_topic_score_codex":0.000027355773,"about_ca_topic_score_gemma":0.000006295048,"teacher_disagreement_score":0.9948023,"about_ca_system_score_codex":0.00011634897,"about_ca_system_score_gemma":0.00021852586,"threshold_uncertainty_score":0.5270733},"labels":[],"label_agreement":null},{"id":"W3110063483","doi":"","title":"Molecular Pharmacology Gordon Research Conference (Italy) - Evidence for a PKC/phorbol ester-dependent toggle switch regulating GPCR responsiveness: insight from dopaminergic D1-like receptors","year":2009,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"G protein-coupled receptor; Phorbol ester; Dopaminergic; Receptor; Neuroscience; Molecular Pharmacology; Protein kinase C; Pharmacology; Chemistry; Biology; Signal transduction; Cell biology; Dopamine; Biochemistry","score_opus":0.07755611359201027,"score_gpt":0.3699073732697617,"score_spread":0.29235125967775144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110063483","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.960652,0.0025240006,0.033448942,0.0007760884,0.0008706312,0.0010113277,0.000015264703,0.00004954667,0.0006522162],"genre_scores_gemma":[0.988872,0.0004256505,0.0070721554,0.000784416,0.0004933068,0.00017438286,0.00014299627,0.000053362583,0.0019817676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964053,0.00046934115,0.0005909979,0.0011845097,0.0005421606,0.0008077056],"domain_scores_gemma":[0.99789286,0.0003117282,0.00018386677,0.00063414045,0.00072758796,0.0002497924],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012435322,0.0003879174,0.00042014528,0.00018879768,0.00030602483,0.00014775264,0.0006533596,0.0004220666,0.00050483254],"category_scores_gemma":[0.0004083005,0.00036192866,0.00020525393,0.00030091187,0.00010826428,0.000032691692,0.00025859417,0.000322849,0.000020902795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010815886,0.000100769226,0.00007202395,0.00002111453,0.000074258984,0.000020302432,0.00017025133,0.00034010137,0.9899894,0.0005213344,0.0017263658,0.005882505],"study_design_scores_gemma":[0.0011551915,0.0015256144,0.00009177905,0.00013235128,0.000045992587,0.0000114826635,0.00041354678,0.0013835662,0.9834588,0.0012890657,0.0100239115,0.00046866137],"about_ca_topic_score_codex":0.00016397434,"about_ca_topic_score_gemma":0.00005132942,"teacher_disagreement_score":0.028219981,"about_ca_system_score_codex":0.000089259665,"about_ca_system_score_gemma":0.00031562796,"threshold_uncertainty_score":0.9998833},"labels":[],"label_agreement":null},{"id":"W3110256242","doi":"","title":"9th GPCR Retreat (Canada) - Five serine residues located on the third intracellular loop of human D5 dopaminergic receptor shape the extent of protein kinase C-mediated D5 desensitization","year":2008,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"G protein-coupled receptor; Intracellular; Dopaminergic; Desensitization (medicine); Receptor; Chemistry; Cell biology; G protein-coupled receptor kinase; Serine; Phosphorylation; Biology; Biochemistry; Neuroscience; Dopamine","score_opus":0.012159359354401433,"score_gpt":0.20494081647480217,"score_spread":0.19278145712040073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110256242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99784714,0.00031916937,0.00026092093,0.00042555697,0.000067771245,0.00051040767,0.000021859605,0.00001259707,0.00053456606],"genre_scores_gemma":[0.9962968,0.0001670912,0.00017933112,0.00014368509,0.00008446884,0.00002350395,0.00027829673,0.000025702397,0.0028011089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985989,0.00018205779,0.00038182412,0.00029186843,0.00033535273,0.00021001203],"domain_scores_gemma":[0.9989358,0.000039474144,0.00023149708,0.00044152827,0.00029395445,0.000057713158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002843778,0.00020160877,0.00021986307,0.000035709527,0.00018638954,0.000009280133,0.00023877068,0.00013049015,0.00032198895],"category_scores_gemma":[0.00015964115,0.00011690794,0.000076560034,0.00020026632,0.00015438751,0.000004093552,0.00007491798,0.00012597658,0.000002922083],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001168476,0.000068257796,0.00009917136,0.00002183562,0.000055733173,0.000008336734,0.00005611113,0.00026234906,0.9963296,0.0006490725,0.0021880358,0.00014464866],"study_design_scores_gemma":[0.00030622646,0.00056413625,0.00016964803,0.000051883148,0.000015280686,0.000005357548,0.0004090964,0.0010873803,0.9963761,0.000032333537,0.00084485946,0.00013772922],"about_ca_topic_score_codex":0.008817505,"about_ca_topic_score_gemma":0.0068819732,"teacher_disagreement_score":0.0022665428,"about_ca_system_score_codex":0.000034272678,"about_ca_system_score_gemma":0.00015706744,"threshold_uncertainty_score":0.9977829},"labels":[],"label_agreement":null},{"id":"W3110292664","doi":"","title":"11th GPCR Retreat (Canada) - A deletion approach highlights unexpected subtype-specific roles of the third intracellular loop of D1-like dopaminergic receptors: revisiting the extended ternary complex model","year":2010,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"G protein-coupled receptor; Dopaminergic; Receptor; Intracellular; Ternary complex; Neuroscience; Biology; Computational biology; Cell biology; Genetics; Dopamine; Biochemistry","score_opus":0.01169210440312131,"score_gpt":0.20261507442110244,"score_spread":0.19092297001798111,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110292664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98150134,0.000725961,0.014583718,0.00031992054,0.0002543343,0.00032534532,0.000016373564,0.000016083439,0.002256933],"genre_scores_gemma":[0.99358076,0.0002097416,0.0048201876,0.00006458807,0.00029365654,0.000013030363,0.00011577281,0.000031001066,0.0008712639],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99831325,0.00013847584,0.00048802205,0.0004048691,0.0003922941,0.0002630655],"domain_scores_gemma":[0.99860764,0.000027118507,0.00034913732,0.0007327441,0.00021997589,0.00006341217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034070673,0.00024225432,0.00028980648,0.000035375328,0.00017107492,0.000023531486,0.0005440227,0.00019703162,0.000102432576],"category_scores_gemma":[0.000035755293,0.00013988483,0.0001681151,0.00018508478,0.00014276244,0.0000069813545,0.00015984804,0.00024404457,5.787097e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066605906,0.00004481443,0.00009461462,0.000028274817,0.000048663802,7.2821626e-7,0.00005767443,0.0011652291,0.99260575,0.003866201,0.0010869881,0.00093447434],"study_design_scores_gemma":[0.00033589895,0.00006751825,0.00020502367,0.00003237194,0.000033696288,0.000016284252,0.00037397165,0.034055457,0.95934683,0.00017939019,0.0051374626,0.00021610386],"about_ca_topic_score_codex":0.00173607,"about_ca_topic_score_gemma":0.002632952,"teacher_disagreement_score":0.033258907,"about_ca_system_score_codex":0.000020113568,"about_ca_system_score_gemma":0.00014847939,"threshold_uncertainty_score":0.57043374},"labels":[],"label_agreement":null},{"id":"W3110913634","doi":"10.1002/alz.043859","title":"Leveraging amino acid sensors as therapeutic targets for tauopathies and related dementias","year":2020,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"mTORC1; Tauopathy; Arginine; Biology; Cell biology; Knockout mouse; Extracellular; Neurodegeneration; Neuroscience; Receptor; Biochemistry; Signal transduction; Amino acid; Internal medicine; Disease; Medicine; PI3K/AKT/mTOR pathway","score_opus":0.023532710672611718,"score_gpt":0.24843345122630214,"score_spread":0.22490074055369041,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3110913634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.62270194,0.35442,0.018890258,0.0015447091,0.00060640095,0.00091734587,0.00002126294,0.00008374982,0.00081434683],"genre_scores_gemma":[0.99532664,0.00032863626,0.0027577386,0.0012465537,0.00013444458,0.00003336423,0.00011084707,0.000038943548,0.000022832402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888927,0.000048948103,0.00023829595,0.00042637976,0.000112274975,0.00028483165],"domain_scores_gemma":[0.9995776,0.000009363129,0.000093292525,0.0001473508,0.00005748098,0.00011495869],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015609116,0.00019382096,0.00015824,0.000024043065,0.00017121025,0.000051160456,0.00012381827,0.00011429898,0.00024575222],"category_scores_gemma":[0.000023066132,0.00019026244,0.00009872001,0.000055847544,0.000041299263,0.000008511481,0.00009685927,0.00007346432,0.000018278206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006682332,0.000017938732,0.00023558116,0.000008149781,0.0043016863,0.0000037318744,0.0005146556,0.00003370743,0.97985876,0.00032847983,0.0008932992,0.013737172],"study_design_scores_gemma":[0.0007056925,0.0003482611,0.00010172586,0.0000059659023,0.0022103426,0.000009949075,0.00031842254,0.00057447323,0.958527,0.0004998339,0.036427133,0.000271159],"about_ca_topic_score_codex":0.0000068348627,"about_ca_topic_score_gemma":0.0000010866517,"teacher_disagreement_score":0.37262473,"about_ca_system_score_codex":0.0000011173744,"about_ca_system_score_gemma":0.00002494633,"threshold_uncertainty_score":0.7758677},"labels":[],"label_agreement":null},{"id":"W3111305167","doi":"10.1152/ajpcell.00142.2020","title":"Increased cholinergic activity under conditions of low estrogen leads to adverse cardiac remodeling","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Internal medicine; Ovariectomized rat; Endocrinology; Cholinergic; Myocyte; Cardiac function curve; Heart failure; Medicine; Vesicular acetylcholine transporter; Estrogen; Contractility; Choline acetyltransferase; Muscle hypertrophy","score_opus":0.009019761009625659,"score_gpt":0.24311534176495378,"score_spread":0.23409558075532813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111305167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99774015,0.00012105352,0.0014574962,0.00025408558,0.00019208767,0.00012851409,0.00005259848,0.000008069771,0.000045964163],"genre_scores_gemma":[0.99597776,0.00011861613,0.001754208,0.0013795675,0.0006667921,0.0000061886417,0.000052291492,0.00003455673,0.000010040638],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982792,0.00034804843,0.0004888574,0.0003983601,0.00013869195,0.0003468067],"domain_scores_gemma":[0.9983537,0.00005903957,0.000707236,0.00029611526,0.00028602636,0.0002978459],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016833225,0.000256303,0.0007928579,0.00008415106,0.00007098677,0.0000037380105,0.0003715682,0.0001266008,0.0000787048],"category_scores_gemma":[0.00007499311,0.00023201072,0.00044631682,0.00023996118,0.00029258803,0.000012359539,0.00013899426,0.00027802322,0.000012796021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007806516,0.00011768874,0.000071985276,0.000019852154,0.00013359568,9.783604e-7,0.00007383569,0.04964274,0.94851303,0.000033753193,0.00036027288,0.00025159866],"study_design_scores_gemma":[0.00070907036,0.0030340352,0.0029868244,0.000020323349,0.00006979156,0.000006316435,0.00037735904,0.00037225848,0.9916414,0.00016439978,0.00036548846,0.00025271837],"about_ca_topic_score_codex":0.00004097042,"about_ca_topic_score_gemma":7.5250415e-7,"teacher_disagreement_score":0.049270485,"about_ca_system_score_codex":0.000020997308,"about_ca_system_score_gemma":0.00020129794,"threshold_uncertainty_score":0.9461122},"labels":[],"label_agreement":null},{"id":"W3111854290","doi":"10.1016/j.cell.2020.11.014","title":"How GPCR Phosphorylation Patterns Orchestrate Arrestin-Mediated Signaling","year":2020,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Canadian Institutes of Health Research; Office of Science; National Institutes of Health; Human Frontier Science Program","keywords":"Biology; Arrestin; Phosphorylation; G protein-coupled receptor; Signal transduction; Cell biology; Computational biology","score_opus":0.01773920652489172,"score_gpt":0.20537306946284065,"score_spread":0.18763386293794893,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111854290","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9628566,0.0003412628,0.03574848,0.00037303136,0.00013638841,0.000113080845,0.000015255467,0.00002754387,0.00038836166],"genre_scores_gemma":[0.99758023,0.00005718616,0.0008985327,0.00046892618,0.00040500326,0.000006973901,0.0002497734,0.000025263185,0.0003080979],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992652,0.000033769702,0.000119507065,0.00029077448,0.000102511454,0.00018826083],"domain_scores_gemma":[0.99961746,0.000010637431,0.00007325314,0.00012093081,0.000045484812,0.00013222908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007424766,0.00012922783,0.000100560566,0.000011583756,0.000052721356,0.00006307357,0.000121604106,0.00011527949,0.000112301735],"category_scores_gemma":[0.00004940135,0.00012607548,0.00006459055,0.000062144034,0.000013344358,0.0000040469404,0.00003918518,0.000092861854,0.000029460856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022321427,0.000012022424,0.00056041346,0.000023421853,0.000008704349,0.000005080354,0.000081020364,0.0002551551,0.99832386,0.000006812735,0.00031133363,0.00038982948],"study_design_scores_gemma":[0.00029105655,0.00015353995,0.00007598791,0.000007735262,0.000009482649,8.3747636e-7,0.00016524177,0.0010128143,0.9892858,0.000021879308,0.00881302,0.00016259622],"about_ca_topic_score_codex":0.000005074305,"about_ca_topic_score_gemma":0.0000011921776,"teacher_disagreement_score":0.03484995,"about_ca_system_score_codex":0.000005429687,"about_ca_system_score_gemma":0.00003501783,"threshold_uncertainty_score":0.51412094},"labels":[],"label_agreement":null},{"id":"W3111903967","doi":"","title":"1st Annual Brain Health Research Day (Canada) - Evidence for a PKC/phorbol ester-dependent toggle switch regulating GPCR responsiveness: insight from dopaminergic D1-like receptors","year":2009,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"G protein-coupled receptor; Phorbol ester; Dopaminergic; Protein kinase C; Receptor; Neuroscience; Phorbol; Chemistry; Signal transduction; Cell biology; Biology; Dopamine; Biochemistry","score_opus":0.07558388069849081,"score_gpt":0.3544206790068519,"score_spread":0.2788367983083611,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111903967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9644251,0.0043067634,0.019936295,0.008326866,0.0011382591,0.0013480241,0.000110590176,0.000049617724,0.00035848445],"genre_scores_gemma":[0.9834934,0.00025587715,0.00669691,0.0029920102,0.00078904734,0.000080856466,0.00025779422,0.000056319845,0.0053777723],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9959849,0.0006173773,0.00064624345,0.0010408241,0.00082733476,0.0008833178],"domain_scores_gemma":[0.99762183,0.0005831514,0.0002073464,0.0007189578,0.0005164678,0.0003522196],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002640931,0.00033185922,0.00041002457,0.00013142927,0.00050645496,0.000113099624,0.000531972,0.0002648143,0.00016967095],"category_scores_gemma":[0.0011636779,0.00030339335,0.0001327317,0.00029736586,0.000057261746,0.000027928452,0.00018885339,0.0002850521,0.0000043957616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006722581,0.0000693075,0.00013779849,0.00002827244,0.000043697517,0.000008208095,0.000416589,0.00021178975,0.9397122,0.0002936133,0.039754055,0.018652197],"study_design_scores_gemma":[0.0014521151,0.0028987855,0.0010047007,0.000399485,0.000015361706,0.000014594843,0.002833276,0.00065548235,0.84887624,0.0007675158,0.14032505,0.00075739087],"about_ca_topic_score_codex":0.023155944,"about_ca_topic_score_gemma":0.04725071,"teacher_disagreement_score":0.100571,"about_ca_system_score_codex":0.00022101722,"about_ca_system_score_gemma":0.0015195649,"threshold_uncertainty_score":0.9999418},"labels":[],"label_agreement":null},{"id":"W3112152129","doi":"","title":"7th GPCR Retreat (USA) - Study of the differential regulation of the human dopamine D1 and D5 receptor responsiveness by phorbol-12-myristate-13-acetate","year":2006,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Phorbol; Dopamine; Receptor; Chemistry; Dopamine receptor D1; Dopamine receptor; Endocrinology; Biology; Internal medicine; Medicine; Protein kinase C; Biochemistry; Signal transduction","score_opus":0.007489960812810502,"score_gpt":0.22297482622831608,"score_spread":0.21548486541550557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112152129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987253,0.00010946459,0.00025208064,0.00004571834,0.00014857562,0.00037997967,0.000030965813,0.0000043382074,0.00030357038],"genre_scores_gemma":[0.99523425,0.000025201654,0.000041103496,0.000011843418,0.00006640994,0.000010162324,0.00005270635,0.00001797064,0.0045403624],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99881124,0.00022614344,0.00032410197,0.00027576086,0.00021853414,0.00014424293],"domain_scores_gemma":[0.9992337,0.000015388972,0.00021736801,0.00041295512,0.00009503673,0.00002554155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017537641,0.00015626677,0.00019956105,0.000023422752,0.00015929641,0.000018459601,0.0002027906,0.00009638803,0.0001492334],"category_scores_gemma":[0.000021718915,0.00009122577,0.000083100254,0.00009083803,0.000106229105,0.0000042212237,0.00015596751,0.00006606339,3.38376e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014275817,0.0001666014,0.009972707,0.000012225327,0.00003721246,9.897505e-8,0.000076427146,0.000044983684,0.9884404,0.00009160314,0.00076785067,0.00024716143],"study_design_scores_gemma":[0.00092520757,0.00041796372,0.06624124,0.000016330065,0.00003431564,0.000001295224,0.00024972777,0.000034548753,0.9311649,0.00009618705,0.0007067885,0.00011146406],"about_ca_topic_score_codex":0.00051780307,"about_ca_topic_score_gemma":0.00047230758,"teacher_disagreement_score":0.05727544,"about_ca_system_score_codex":0.000009886714,"about_ca_system_score_gemma":0.00001935294,"threshold_uncertainty_score":0.37200788},"labels":[],"label_agreement":null},{"id":"W3112206493","doi":"10.1111/1440-1681.13447","title":"Early nebivolol treatment is beneficial in myocardial infarction in rats partly through β3‐adrenoceptor remodelling","year":2020,"lang":"en","type":"article","venue":"Clinical and Experimental Pharmacology and Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Fondation France-Japon de l'EHESS; Menarini Group; Fédération Française de Cardiologie; Fondation Daniel Langlois pour l'Art, la Science et la Technologie","keywords":"Nebivolol; Internal medicine; Contractility; Medicine; Myocardial infarction; Cardiology; Inotrope; Ventricle; Metoprolol; Endocrinology; Blood pressure","score_opus":0.04505182594777404,"score_gpt":0.3514069542195813,"score_spread":0.3063551282718073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112206493","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99644226,0.002291552,0.00003660779,0.000449976,0.0004725411,0.00022623448,0.000011896889,0.000007452848,0.00006145722],"genre_scores_gemma":[0.99316406,0.0019286013,0.00013567078,0.003654962,0.0010084503,0.00004151669,0.000042610136,0.000012686599,0.000011449141],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985596,0.00020229268,0.0003900731,0.00055400614,0.00003800339,0.00025603405],"domain_scores_gemma":[0.99970365,0.00004048624,0.00006650943,0.00006434564,0.0000122559895,0.00011276121],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010320339,0.00018800012,0.0003651143,0.000020609856,0.000072566974,0.000008544146,0.000066860135,0.00030174988,0.00015759197],"category_scores_gemma":[0.000007938662,0.00017046714,0.00010540476,0.000054686403,0.00019577079,0.000012125958,0.00009684734,0.00018131951,0.0000060647026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017280425,0.00021343157,0.003558393,0.0000069323846,0.000072298644,0.000004870683,0.00093096966,0.00019942522,0.9918153,0.00004654663,0.00022682166,0.0011969584],"study_design_scores_gemma":[0.0048003807,0.0040601655,0.003419414,0.000008091734,0.00003445922,0.000004566393,0.00048395063,0.0020116542,0.9788421,0.0005409043,0.0054733697,0.0003209823],"about_ca_topic_score_codex":0.00007822483,"about_ca_topic_score_gemma":0.0000049764913,"teacher_disagreement_score":0.012973248,"about_ca_system_score_codex":0.000010900077,"about_ca_system_score_gemma":0.000026721757,"threshold_uncertainty_score":0.69514483},"labels":[],"label_agreement":null},{"id":"W3113210257","doi":"10.1002/alz.047086","title":"Validation of a new serum anticholinergic assay using anticholinergic burden scales and cognitive assessments in older adults with mild cognitive impairment or major depressive disorder","year":2020,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Baycrest Hospital; St. Michael's Hospital; Sunnybrook Health Science Centre; Centre for Addiction and Mental Health","funders":"","keywords":"Anticholinergic; Major depressive disorder; Internal medicine; Cognition; Anticholinergic agents; Psychology; Medicine; Cognitive impairment; Psychiatry; Clinical psychology","score_opus":0.020297655318483272,"score_gpt":0.2903311197402012,"score_spread":0.27003346442171794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3113210257","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9766377,0.011117483,0.011355152,0.00007526634,0.000046415586,0.0006857034,0.00005302393,0.000008893332,0.00002036021],"genre_scores_gemma":[0.9965242,0.00016219354,0.0027171005,0.00018074983,0.0001235816,0.000023878747,0.00022317833,0.000039468898,0.00000564376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984628,0.000119939185,0.00036111617,0.00053878286,0.0002293627,0.00028801322],"domain_scores_gemma":[0.999309,0.000028703005,0.00023647459,0.00010677395,0.00017014309,0.00014890975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013410226,0.00026615654,0.00028529877,0.000063597516,0.00007283582,0.000041607404,0.00010609988,0.000124883,0.0001044032],"category_scores_gemma":[0.00003127184,0.00021772104,0.000056899065,0.00019226731,0.000061987725,0.000028588784,0.00013655574,0.000107028995,0.0000015497319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.011168196,0.0013330135,0.30760276,0.0003038562,0.02607835,0.00013459098,0.006039718,0.002576514,0.5940285,0.000027299373,0.00023892509,0.0504683],"study_design_scores_gemma":[0.011817105,0.001233647,0.01936665,0.00062608253,0.005920409,0.000016338747,0.00265849,0.0051936805,0.9525473,0.000013993493,0.000025466032,0.00058083545],"about_ca_topic_score_codex":0.00019511301,"about_ca_topic_score_gemma":0.000054463806,"teacher_disagreement_score":0.35851884,"about_ca_system_score_codex":0.000002448828,"about_ca_system_score_gemma":0.00010438681,"threshold_uncertainty_score":0.8878406},"labels":[],"label_agreement":null},{"id":"W3113340395","doi":"10.1074/jbc.ra120.014726","title":"Optimization of a peptide ligand for the adhesion GPCR ADGRG2 provides a potent tool to explore receptor biology","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Science Fund for Distinguished Young Scholars; National College Students Innovation and Entrepreneurship Training Program; Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"G protein-coupled receptor; Computational biology; Receptor; Ligand (biochemistry); Peptide; Biology; Cell biology; Biochemistry","score_opus":0.049497238301109525,"score_gpt":0.2719625114158733,"score_spread":0.22246527311476377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3113340395","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91629803,0.00081773964,0.081169374,0.001323425,0.000094897594,0.00023994013,0.000023369865,0.0000050542735,0.000028158813],"genre_scores_gemma":[0.9811402,0.00047508348,0.017028935,0.00051689334,0.0007359109,0.000020262161,0.000037057147,0.000012233384,0.0000334225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990242,0.000033310575,0.00046935136,0.00021007819,0.00009395108,0.00016909254],"domain_scores_gemma":[0.9990855,0.00006352828,0.0003504582,0.00012187678,0.00025943734,0.00011921544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030221645,0.00014060106,0.0002613444,0.000011162707,0.000057757014,0.000014947376,0.00029785713,0.00021964451,0.00007815716],"category_scores_gemma":[0.0009731975,0.00008034883,0.00023552669,0.00007357989,0.000053297794,0.0000042570796,0.000094969684,0.00011692216,9.1518683e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007288103,0.000040581832,0.00014216952,0.000036981306,0.000056000274,6.969464e-7,0.00007114724,0.0022857937,0.9934684,0.0000069661064,0.0013963043,0.0017661536],"study_design_scores_gemma":[0.00047476697,0.001554282,0.000021234047,0.000035221386,0.000022592538,0.000014327344,0.00038821503,0.00041981036,0.98572254,0.000044597706,0.011184366,0.00011802495],"about_ca_topic_score_codex":6.685819e-7,"about_ca_topic_score_gemma":5.2425378e-8,"teacher_disagreement_score":0.06484216,"about_ca_system_score_codex":0.000011501969,"about_ca_system_score_gemma":0.00006970119,"threshold_uncertainty_score":0.327653},"labels":[],"label_agreement":null},{"id":"W3113873160","doi":"10.3389/fphar.2020.600132","title":"Signal Transduction Profiling of Angiotensin II Type 1 Receptor With Mutations Associated to Atrial Fibrillation in Humans","year":2020,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Signal transduction; Cell biology; Receptor; Angiotensin II; Angiotensin II receptor type 1; Biology; Kinase; G protein-coupled receptor; Phosphorylation; Arrestin; Protein kinase A; Internal medicine; Endocrinology; Medicine; Genetics","score_opus":0.014039517632604002,"score_gpt":0.26202344491341695,"score_spread":0.24798392728081295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3113873160","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9806738,0.00021587958,0.017560497,0.00050906127,0.0006372965,0.00035911117,0.000015201112,0.000008599018,0.000020580179],"genre_scores_gemma":[0.98623884,0.00003803323,0.013018881,0.00015050385,0.00034285858,0.000005458636,0.00016763058,0.000015465317,0.000022343842],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917245,0.00010810092,0.00023312494,0.00024425198,0.00007788935,0.0001641929],"domain_scores_gemma":[0.9997404,0.0000070548144,0.00007826662,0.000041525844,0.00008027154,0.000052464224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014345351,0.00009472638,0.00018606962,0.00009485048,0.000038915903,0.0000035144096,0.00006605422,0.00012753745,0.00012792462],"category_scores_gemma":[0.00002902104,0.00009868035,0.00004931641,0.00033031372,0.000028569082,0.000006107374,0.000018968612,0.000092324175,0.0000010017966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009628749,0.00001756533,0.007294337,0.0000066345997,0.000060149912,0.0000016080868,0.0006279606,0.049337924,0.93914765,0.0000052419023,0.0018250038,0.0007130676],"study_design_scores_gemma":[0.001812048,0.0013879677,0.00047040635,0.000013567055,0.000040342526,6.857009e-7,0.00032655316,0.004763346,0.98857296,0.00003220848,0.0024177795,0.00016216631],"about_ca_topic_score_codex":0.0000135007285,"about_ca_topic_score_gemma":0.000014113547,"teacher_disagreement_score":0.049425296,"about_ca_system_score_codex":0.000034836703,"about_ca_system_score_gemma":0.00007820334,"threshold_uncertainty_score":0.40240678},"labels":[],"label_agreement":null},{"id":"W3116749864","doi":"10.1021/acs.bioconjchem.0c00670","title":"Trifluorinated Keto–Enol Tautomeric Switch in Probing Domain Rotation of a G Protein-Coupled Receptor","year":2020,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"University of South Florida","keywords":"Chemistry; Tautomer; Ligand (biochemistry); Transmembrane domain; G protein-coupled receptor; Molecular dynamics; Biophysics; Domain (mathematical analysis); Conformational change; Enol; Population; Drug discovery; Receptor; Stereochemistry; Computational chemistry; Biochemistry","score_opus":0.010909927779153929,"score_gpt":0.2196254940128245,"score_spread":0.20871556623367057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3116749864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99728173,0.00034359298,0.0011147701,0.00019040811,0.000046734483,0.00059962063,0.000016716287,0.000031233394,0.00037516456],"genre_scores_gemma":[0.9969048,0.000042262745,0.0022558244,0.00006275389,0.00017842052,0.00015015664,0.00018052083,0.000039276994,0.00018601911],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853235,0.0000391188,0.00046650026,0.0004962878,0.00017205464,0.00029366458],"domain_scores_gemma":[0.999308,0.000005580423,0.00023417958,0.000225974,0.00009993134,0.00012637244],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020353885,0.00023169265,0.00028717343,0.000027934779,0.00004017539,0.000021984524,0.00023216226,0.00024975548,0.0002658001],"category_scores_gemma":[0.00010651354,0.00023692202,0.000109006345,0.00030216054,0.000050421506,0.000007466296,0.000083185325,0.00015501986,0.000010844435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002317279,0.00005971803,0.0001819545,0.00024763134,0.000031155043,0.000004029744,0.00024241298,0.0000423009,0.99834955,0.000016920354,0.000046635858,0.0005459697],"study_design_scores_gemma":[0.0012898634,0.00016829956,0.000026180029,0.00007524849,0.000007151265,0.0000036356698,0.00038674963,0.0004688791,0.99559677,0.00004337537,0.0016661534,0.00026770926],"about_ca_topic_score_codex":0.000024245866,"about_ca_topic_score_gemma":0.0000012144029,"teacher_disagreement_score":0.0027527888,"about_ca_system_score_codex":0.000030919677,"about_ca_system_score_gemma":0.00011964459,"threshold_uncertainty_score":0.96614},"labels":[],"label_agreement":null},{"id":"W3117360023","doi":"10.1016/j.cellsig.2020.109906","title":"Signaling diversity of mu- and delta- opioid receptor ligands: Re-evaluating the benefits of β-arrestin/G protein signaling bias","year":2020,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Functional selectivity; Arrestin; G protein-coupled receptor; μ-opioid receptor; Opioid; Receptor; Signal transduction; G protein; Opioid receptor; δ-opioid receptor; Pharmacology; Neuroscience; Bioinformatics; Biology; Medicine; Cell biology; Internal medicine","score_opus":0.06217993391744102,"score_gpt":0.2509770268861706,"score_spread":0.18879709296872954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3117360023","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97061354,0.004882512,0.023733297,0.00010436768,0.00008892597,0.0004975287,0.000028619335,0.000020407293,0.00003080021],"genre_scores_gemma":[0.99210167,0.00010985835,0.007162591,0.00011685509,0.00036454428,0.000013559401,0.000062637846,0.000045076704,0.00002322398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977765,0.00016947117,0.00066114153,0.00057033246,0.0004725622,0.0003499966],"domain_scores_gemma":[0.9986066,0.00011521715,0.00054457725,0.00026976172,0.0002958738,0.00016795598],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013107543,0.00029991457,0.0004242232,0.00005415723,0.00039614324,0.00004160724,0.0004591202,0.00020997833,0.00011389826],"category_scores_gemma":[0.00046557048,0.00025468454,0.00020986222,0.00024416155,0.0001332317,0.000014831085,0.00055267056,0.00024294747,0.0000023724633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018551473,0.000029384986,0.0008094283,0.00020072913,0.000103974264,0.0000016725745,0.0013856414,0.013311728,0.982122,0.00013029117,0.000013675151,0.0017059433],"study_design_scores_gemma":[0.00052778405,0.00078955636,0.000011784665,0.0002805851,0.000091053764,0.0000012046739,0.00095527706,0.0058999807,0.9909136,0.00014816692,0.00009821794,0.00028277605],"about_ca_topic_score_codex":0.000050373106,"about_ca_topic_score_gemma":0.0000021893454,"teacher_disagreement_score":0.021488113,"about_ca_system_score_codex":0.000010655836,"about_ca_system_score_gemma":0.00009059031,"threshold_uncertainty_score":0.9999905},"labels":[],"label_agreement":null},{"id":"W3121213324","doi":"10.2139/ssrn.3382436","title":"Causal Link between n-3 Polyunsaturated Fatty Acid Deficiency and Motivation Deficits","year":2019,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"LabEx BRAIN; Université de Bordeaux; Fondation de France; Conseil régional de Bourgogne-Franche-Comté; Agence Nationale de la Recherche; Institut National de la Recherche Agronomique; Fondation pour la Recherche Médicale; Institut National de la Santé et de la Recherche Médicale; National Alliance for Research on Schizophrenia and Depression","keywords":"Polyunsaturated fatty acid; Psychology; Medicine; Developmental psychology; Internal medicine; Fatty acid; Endocrinology; Chemistry; Biochemistry","score_opus":0.00751795150645569,"score_gpt":0.22059043442232418,"score_spread":0.2130724829158685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3121213324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9771681,0.0046701697,0.017584778,0.0001656129,0.0001400739,0.00010840963,0.0000030980502,0.000009511946,0.00015028233],"genre_scores_gemma":[0.9972307,0.0016697713,0.00020575785,0.000049093425,0.00046917502,0.0000013993136,0.000042394782,0.000022241498,0.0003094738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983387,0.000059351893,0.00020985061,0.0002505446,0.00015129277,0.0009902406],"domain_scores_gemma":[0.9995842,0.0000108729355,0.00012065094,0.00012901722,0.00008418067,0.00007108657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058619055,0.00014902433,0.00014177781,0.000055859964,0.0001374237,0.000052825497,0.00013323747,0.00016706173,0.000026454942],"category_scores_gemma":[0.000047583922,0.00012912187,0.0000612803,0.00009399077,0.00002162485,0.000011239409,0.0000410665,0.00061415136,0.000013448921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036305137,0.000008684539,0.01536614,0.0000049688015,0.000055296267,4.6727683e-7,0.000028873372,0.000023945095,0.9649163,0.005659023,0.0000063477096,0.013893683],"study_design_scores_gemma":[0.0020788833,0.0027108449,0.019055333,0.00004687984,0.000086743064,0.00048574238,0.0009344324,0.0001595319,0.942894,0.029098187,0.0017224423,0.00072698126],"about_ca_topic_score_codex":0.000011715415,"about_ca_topic_score_gemma":0.000025509036,"teacher_disagreement_score":0.023439163,"about_ca_system_score_codex":0.000063916814,"about_ca_system_score_gemma":0.0004527822,"threshold_uncertainty_score":0.5265437},"labels":[],"label_agreement":null},{"id":"W3122232093","doi":"10.2139/ssrn.3155924","title":"Consequences of NMDA Receptor Deficiency Can Be Rescued in the Adult Brain","year":2018,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"NMDA receptor; Neuroscience; Receptor; Medicine; Biology; Psychology; Internal medicine","score_opus":0.008537814211920163,"score_gpt":0.24747221713132456,"score_spread":0.2389344029194044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3122232093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99480546,0.00088713574,0.001318542,0.002253525,0.00013350163,0.000093742055,0.000004849409,0.0000025536463,0.0005007131],"genre_scores_gemma":[0.9974877,0.0012392451,0.00017131398,0.00055705773,0.0002825851,0.0000042500083,0.000008080064,0.000010199704,0.00023952685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983268,0.00018338076,0.00025704817,0.00017076104,0.0001874791,0.00087453227],"domain_scores_gemma":[0.9995008,0.000021232157,0.00013526087,0.00016690818,0.00014310502,0.00003271185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016383843,0.000105498344,0.0001147104,0.000049538234,0.0001273026,0.000021383215,0.00036934536,0.0000913066,0.000050715946],"category_scores_gemma":[0.00020455303,0.000072027506,0.000079272846,0.00014019996,0.00016979211,0.0000039501247,0.000025148187,0.00043666427,0.0000022229156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006109461,0.00003024653,0.0003577368,0.0000025211045,0.000020711039,3.7846763e-7,0.00029904358,0.000004961295,0.9692312,0.027443819,0.00032096278,0.0022273313],"study_design_scores_gemma":[0.0006445824,0.0019988539,0.00006331485,0.00002640367,0.000009113563,0.00013588807,0.0052803294,0.000008230744,0.95987016,0.02812257,0.0036637203,0.00017681526],"about_ca_topic_score_codex":0.00019780546,"about_ca_topic_score_gemma":0.0027209623,"teacher_disagreement_score":0.009361017,"about_ca_system_score_codex":0.00006255031,"about_ca_system_score_gemma":0.0010798554,"threshold_uncertainty_score":0.29371965},"labels":[],"label_agreement":null},{"id":"W3124178733","doi":"10.1038/s41422-020-00464-8","title":"Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury","year":2021,"lang":"en","type":"article","venue":"Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Peking University Health Science Center; School of Medicine, New York University; Lunds Universitet; Zhejiang University; Peking University; Tongji University; National Natural Science Foundation of China; York University","keywords":"Biology; Allosteric regulation; Allosteric modulator; Endogeny; Matrix (chemical analysis); Cell biology; Arrestin; Receptor; Cartilage; Cartilage oligomeric matrix protein; Biochemistry; G protein-coupled receptor; Anatomy; Materials science; Pathology","score_opus":0.050823680514077915,"score_gpt":0.3336723437599173,"score_spread":0.28284866324583935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124178733","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99603236,0.0017394869,0.00041923908,0.000019464398,0.00013461597,0.00046881632,0.00003666292,0.00001255663,0.0011368186],"genre_scores_gemma":[0.9952259,0.00027183772,0.002203132,0.000036126097,0.00027758445,0.000076918805,0.000102817765,0.00006169351,0.0017439773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99719244,0.0005314857,0.0003450117,0.0006866981,0.0006294333,0.0006149421],"domain_scores_gemma":[0.99810094,0.000040233048,0.0001165964,0.0006671204,0.0008725582,0.00020258197],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009816792,0.00020185551,0.0002778568,0.00011498865,0.00021726431,0.000074358904,0.00033829847,0.00020613341,0.0007013235],"category_scores_gemma":[0.00020388218,0.00020754508,0.00015932345,0.0004842226,0.000088257235,0.000015075339,0.00027818163,0.0003409023,0.000055948618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011731603,0.0001737617,0.0001269023,0.00011495928,0.00004136732,0.000017196975,0.00041226865,0.000038698956,0.99719185,0.000013880769,0.00025695033,0.0014948345],"study_design_scores_gemma":[0.00030635222,0.00061617367,0.000018042336,0.000040780433,0.000010643116,0.000010885942,0.0006749119,0.00015617763,0.9894768,0.000049602204,0.008431434,0.00020817378],"about_ca_topic_score_codex":0.000098522534,"about_ca_topic_score_gemma":0.000007030247,"teacher_disagreement_score":0.008174484,"about_ca_system_score_codex":0.00006334518,"about_ca_system_score_gemma":0.00043513929,"threshold_uncertainty_score":0.84634423},"labels":[],"label_agreement":null},{"id":"W3124283455","doi":"10.1139/bcb-2020-0480","title":"G protein coupled receptor kinase 5 modifies the nucleolar stress response activated by actinomycin D","year":2021,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Molecular biology; Biology; Nucleophosmin; Kinase; Transfection; Small hairpin RNA; Cell culture; Cell biology; RNA; Biochemistry; Gene","score_opus":0.0066649737710611535,"score_gpt":0.21416619923294739,"score_spread":0.20750122546188624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124283455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99500984,0.0035828492,0.00021393801,0.0004232846,0.00010300127,0.00016904286,0.00010764889,0.00002003582,0.00037036368],"genre_scores_gemma":[0.99372196,0.00034373323,0.00026896893,0.00019980353,0.00016991455,0.000050077437,0.00063783495,0.000023897504,0.0045838035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99854696,0.0002470679,0.00022050609,0.00057883066,0.00007653412,0.00033012847],"domain_scores_gemma":[0.99918205,0.000049178554,0.00011747962,0.00043004812,0.00010579786,0.00011546579],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002910511,0.00024660063,0.00019430593,0.000012178063,0.00023639126,0.000048819995,0.00021682779,0.00042075178,0.00034609996],"category_scores_gemma":[0.0001670988,0.00019220464,0.000087097236,0.0000896287,0.00017469052,0.0000040664636,0.00017682232,0.00020053412,0.000008569585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063098327,0.00008741304,0.000064971246,0.000036071917,0.000043762997,0.000004485801,0.00003257283,0.0000024463736,0.9973129,0.000019146582,0.00091409864,0.00085117266],"study_design_scores_gemma":[0.00051895826,0.0001561005,0.000008899193,0.000017520875,0.000013322662,0.000010366468,0.0005043397,0.000029866082,0.94545346,0.000024324543,0.053016827,0.00024598234],"about_ca_topic_score_codex":0.000016140557,"about_ca_topic_score_gemma":0.0000012486017,"teacher_disagreement_score":0.05210273,"about_ca_system_score_codex":0.0000147604605,"about_ca_system_score_gemma":0.00013116172,"threshold_uncertainty_score":0.7837878},"labels":[],"label_agreement":null},{"id":"W3124400884","doi":"10.22541/au.161144035.53972444/v1","title":"Seeing Beyond the Blot: A Critical Look at  Assumptions and Raw Data Interpretation in Western Blotting","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universität Innsbruck; Medizinische Universität Innsbruck; University of Alberta; National Science Foundation","keywords":"Blot; Raw data; Normalization (sociology); Experimental data; Interpretation (philosophy); Computational biology; Data science; Computer science; Biology; Mathematics; Statistics; Biochemistry","score_opus":0.027361048545998284,"score_gpt":0.3137842014541023,"score_spread":0.286423152908104,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3124400884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92382437,0.0033190039,0.070907064,0.0007463399,0.0003866648,0.00024027209,0.000035513247,0.000013901413,0.00052688946],"genre_scores_gemma":[0.9939759,0.0003768827,0.0034134341,0.00048895134,0.00019245053,0.000028052105,0.0010334462,0.000026162506,0.00046475144],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850136,0.00015176037,0.0003041877,0.00070513523,0.0001294438,0.00020808612],"domain_scores_gemma":[0.9989767,0.000077758654,0.00006892237,0.00075911457,0.00006230667,0.000055160646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050230086,0.00019132296,0.00019693446,0.000037230384,0.00011455106,0.00020084938,0.00036784905,0.00028099772,0.00012484635],"category_scores_gemma":[0.00024592,0.00015524916,0.000057710695,0.000035242243,0.00007048262,0.000007554879,0.0032660475,0.00031642246,0.0000028832965],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005672526,0.000098240984,0.005961129,0.00030639823,0.00018646895,0.00003711373,0.0013650267,0.0010924346,0.9799366,0.0003245626,0.00046126533,0.010174054],"study_design_scores_gemma":[0.0022584775,0.00037718023,0.004758971,0.002275556,0.00070045487,0.00051442866,0.007473037,0.21361417,0.7493164,0.0031652376,0.012508452,0.0030376601],"about_ca_topic_score_codex":0.00006992458,"about_ca_topic_score_gemma":0.0009966048,"teacher_disagreement_score":0.2306202,"about_ca_system_score_codex":0.000021040587,"about_ca_system_score_gemma":0.00007628109,"threshold_uncertainty_score":0.6330877},"labels":[],"label_agreement":null},{"id":"W3125247195","doi":"10.1038/s41392-021-00471-0","title":"Cell-type-specific memory consolidation driven by translational control","year":2021,"lang":"en","type":"article","venue":"Signal Transduction and Targeted Therapy","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Consolidation (business); Memory consolidation; Computational biology; Computer science; Biology; Neuroscience; Business","score_opus":0.010289549540377979,"score_gpt":0.2179619746254913,"score_spread":0.20767242508511333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3125247195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87869424,0.020833218,0.098660566,0.0005343869,0.0004715463,0.00024546174,0.000075612064,0.000030242232,0.00045474668],"genre_scores_gemma":[0.99361265,0.0041120737,0.00067220564,0.00031028214,0.0002379718,0.000010114511,0.00063809304,0.000020497579,0.0003861079],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99912167,0.00010765302,0.00017675462,0.00031393892,0.000129965,0.00015002872],"domain_scores_gemma":[0.99965066,0.000010823997,0.00004213439,0.000097033226,0.00012580691,0.000073539486],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000099672216,0.00013803843,0.00012785445,0.000027233074,0.0001310299,0.00003466957,0.000045702804,0.00013377637,0.002326138],"category_scores_gemma":[0.0000017689547,0.00013718299,0.000079483856,0.00008725549,0.00004640369,0.000009526937,0.0000023294122,0.000090182475,0.000004992943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022029558,0.00007539297,0.000072839626,0.0000046361115,0.00005445253,0.0000013615979,0.00010820357,0.0002840919,0.9938931,0.000092480506,0.0010301662,0.0041629868],"study_design_scores_gemma":[0.0019755182,0.00019047076,0.00008921716,0.0000036688414,0.000008981216,0.000013601904,0.00013695926,0.00017570578,0.9504149,0.00018317417,0.046640083,0.00016770717],"about_ca_topic_score_codex":0.000002052609,"about_ca_topic_score_gemma":8.4036725e-7,"teacher_disagreement_score":0.11491843,"about_ca_system_score_codex":0.000004193846,"about_ca_system_score_gemma":0.000052379313,"threshold_uncertainty_score":0.9985859},"labels":[],"label_agreement":null},{"id":"W3125735562","doi":"10.1101/2021.01.28.427950","title":"Vasopressin V2 is a promiscuous G protein-coupled receptor that is biased by its peptide ligands","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Diabetes Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Vasopressin; G protein-coupled receptor; Receptor; Agonist; Ligand (biochemistry); Functional selectivity; G protein; Chemistry; Vasopressin receptor; Biology; Peptide; Cell biology; Biochemistry; Biophysics; Endocrinology; Antagonist","score_opus":0.014067976460633215,"score_gpt":0.21677294940393657,"score_spread":0.20270497294330336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3125735562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865591,0.0077837165,0.0019180523,0.00037286925,0.00090124615,0.0015941779,0.00068440754,0.00017387206,0.000012584569],"genre_scores_gemma":[0.9912156,0.0010641244,0.0045179604,0.000973317,0.00084328174,0.00067060685,0.000020366304,0.00032923618,0.00036549536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9952388,0.00015417175,0.00073760125,0.0022337881,0.00067903084,0.0009566474],"domain_scores_gemma":[0.9961542,0.000017047094,0.00068382866,0.0018944241,0.00075645,0.00049406826],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.000592544,0.0010596223,0.0009191849,0.00015101854,0.00027892736,0.0006016048,0.00094175764,0.0015392097,0.00089432223],"category_scores_gemma":[0.0002106676,0.0011131902,0.0005229287,0.0003260222,0.00009582509,0.00002552049,0.00091457646,0.0008532177,0.0000662801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008039099,0.0002072183,0.00027508388,0.00041690518,0.0004643647,0.000024865863,0.00003098107,0.000008430901,0.99121904,0.0000096733165,0.0072594895,0.000003525303],"study_design_scores_gemma":[0.00089156476,0.00016113694,0.00017603034,0.0007084889,0.00014637134,5.9234257e-8,0.000013662914,0.00029164096,0.97662205,7.333353e-7,0.019677905,0.0013103577],"about_ca_topic_score_codex":0.00005813629,"about_ca_topic_score_gemma":0.0000023351417,"teacher_disagreement_score":0.014597023,"about_ca_system_score_codex":0.000109114066,"about_ca_system_score_gemma":0.0010303557,"threshold_uncertainty_score":0.999757},"labels":[],"label_agreement":null},{"id":"W3127231551","doi":"10.1101/2021.01.31.429059","title":"Single cell analysis of population-wide nuclear and cytosolic drug responses using high-content FRET imaging: measuring protein kinase activation in rat primary striatal neurons","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Weston Brain Institute; Faculty of Medicine, McGill University; McGill University","keywords":"Medium spiny neuron; Förster resonance energy transfer; Biology; Striatum; Population; Cell biology; Dopamine; High-content screening; Intracellular; Cytosol; Cytoplasm; Single-cell analysis; Cell; Neuroscience; Biochemistry; Fluorescence; Enzyme","score_opus":0.019810057580382484,"score_gpt":0.20458428851144408,"score_spread":0.1847742309310616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127231551","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99709743,0.0005476855,0.0015065463,0.0000443654,0.00018437047,0.0005094344,0.00007876478,0.000030621864,7.7236774e-7],"genre_scores_gemma":[0.9941023,0.00005222331,0.005551253,0.00006396371,0.00009808241,0.000026060121,0.000014996854,0.00008852784,0.0000026174002],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974989,0.00033819306,0.0006219238,0.0009180566,0.00029498458,0.00032789257],"domain_scores_gemma":[0.99828404,0.000033952583,0.0005469555,0.0007164883,0.00029303253,0.0001255186],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047970904,0.0003927678,0.00061626226,0.00048761134,0.000108863285,0.0001678803,0.00023092981,0.00026936253,0.00001269145],"category_scores_gemma":[0.00027425107,0.00046103794,0.00019677485,0.0005119858,0.00004770645,0.00003318648,0.00045963374,0.00032385287,2.2608602e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012985058,0.00013808835,0.01568777,0.00018770664,0.00017889979,0.000010439694,0.000017795805,0.0012525409,0.98237854,0.00001233942,0.000002443283,0.0000035687967],"study_design_scores_gemma":[0.0004525904,0.000033633016,0.055729046,0.00027184183,0.00026260669,1.1478452e-8,0.000027548069,0.0008777475,0.9419095,6.4299894e-7,0.000022973112,0.00041189088],"about_ca_topic_score_codex":0.0007424552,"about_ca_topic_score_gemma":0.00002618582,"teacher_disagreement_score":0.04046909,"about_ca_system_score_codex":0.00014649928,"about_ca_system_score_gemma":0.00025288257,"threshold_uncertainty_score":0.9997841},"labels":[],"label_agreement":null},{"id":"W3127451099","doi":"10.1038/s41386-021-00974-y","title":"Increased functional coupling of the mu opioid receptor in the anterior insula of depressed individuals","year":2021,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University; Douglas Mental Health University Institute","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Fondation pour la Recherche Médicale; Government of Canada; Fondation Fyssen; Agence Nationale de la Recherche; American Foundation for Suicide Prevention","keywords":"Insula; Psychology; Opioidergic; Anterior cingulate cortex; Opioid receptor; μ-opioid receptor; Opioid; Neuroscience; Neuroimaging; Endogenous opioid; Addiction; Internal medicine; Endocrinology; Receptor; Medicine; Cognition; (+)-Naloxone","score_opus":0.012575544922738525,"score_gpt":0.26155968596993223,"score_spread":0.2489841410471937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3127451099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976428,0.0007220889,0.00012252449,0.00018998487,0.0009364368,0.00019413207,0.000034234305,0.0000031736379,0.00015462676],"genre_scores_gemma":[0.9980885,0.00028534068,0.00012428008,0.0012297428,0.00016439808,0.000027286373,0.000025071777,0.000015134635,0.000040284423],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988203,0.00022738568,0.00034639722,0.00026726988,0.00017225213,0.00016641687],"domain_scores_gemma":[0.999314,0.000077957855,0.00018356797,0.0002805811,0.00011560256,0.000028280796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031238163,0.0001163454,0.00018187458,0.00003844482,0.000054274005,0.000007650388,0.00032553592,0.00011058148,0.00035773058],"category_scores_gemma":[0.000117966236,0.00008119447,0.00011918422,0.00023246287,0.0000928479,0.0000031618958,0.00011736232,0.0001755699,0.0000019045801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014991887,0.00015668782,0.0077710166,0.000021140579,0.000035822723,0.0000034226775,0.00007473875,0.00029322135,0.99050397,0.000034359608,0.00068896526,0.00026673308],"study_design_scores_gemma":[0.0013659071,0.000121924815,0.03738149,0.000018687006,0.000025816616,0.000019206138,0.000099262266,0.00009745863,0.9564082,0.000033385775,0.0043494413,0.00007922665],"about_ca_topic_score_codex":0.000011008122,"about_ca_topic_score_gemma":0.000005032355,"teacher_disagreement_score":0.034095775,"about_ca_system_score_codex":0.000004730495,"about_ca_system_score_gemma":0.00011809366,"threshold_uncertainty_score":0.3916899},"labels":[],"label_agreement":null},{"id":"W3128300412","doi":"10.1038/s41598-021-83038-x","title":"Functionally selective activation of the dopamine receptor D2 is mirrored by the protein expression profiles","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Deutsche Forschungsgemeinschaft; Ontario Ministry of Health and Long-Term Care","keywords":"Agonist; Arrestin; Receptor; HEK 293 cells; Cell biology; Dopamine; G protein-coupled receptor; Dopamine receptor; Endogenous agonist; Signal transduction; Quinpirole; Chemistry; Dopamine receptor D2; Functional selectivity; Proteome; Biology; Biochemistry; Dopamine receptor D1; Neuroscience","score_opus":0.008584895738710794,"score_gpt":0.22076304036626962,"score_spread":0.21217814462755882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128300412","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964055,0.00019933343,0.0009657382,0.00038918716,0.0012896603,0.0003801416,0.000010262559,0.0000061436554,0.00035407883],"genre_scores_gemma":[0.981644,0.0000028133427,0.0005895455,0.00005535776,0.000076708464,0.00006291331,0.00019376547,0.000011015351,0.017363902],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869347,0.00009611665,0.00025815133,0.00045757552,0.0003609298,0.00013378102],"domain_scores_gemma":[0.9987451,0.000007721138,0.00028756665,0.00053331064,0.00039755867,0.000028783317],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050947815,0.000094918454,0.000084805695,0.000016019025,0.00030921752,0.00006119095,0.000116572926,0.000082334795,0.00027662824],"category_scores_gemma":[0.00021009741,0.00005514434,0.000098788165,0.0002500301,0.000107522515,0.000007920209,0.000103481434,0.00007640301,0.0000017218472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015737456,0.00004123487,0.0001743633,0.000008659114,0.000015311232,6.5416873e-7,0.000077321936,0.000009145616,0.9606069,0.000012250086,0.0386144,0.00042406714],"study_design_scores_gemma":[0.00006674614,0.000027390772,0.000100742196,0.00003890814,0.0000053449494,0.000014793765,0.00014416446,0.000009842122,0.9407552,0.00047375023,0.058294427,0.00006867716],"about_ca_topic_score_codex":0.000008850857,"about_ca_topic_score_gemma":0.0000031665786,"teacher_disagreement_score":0.019851644,"about_ca_system_score_codex":0.0000147815945,"about_ca_system_score_gemma":0.00022013328,"threshold_uncertainty_score":0.30288854},"labels":[],"label_agreement":null},{"id":"W3128946477","doi":"10.1101/2021.02.02.429298","title":"Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Medical Research Council; Canadian Institutes of Health Research; Science and Engineering Research Board; The Wellcome Trust DBT India Alliance; Department of Science and Technology, Ministry of Science and Technology, India; Department of Biotechnology, Ministry of Science and Technology, India; Wellcome Trust; Lady Tata Memorial Trust; Indian Institute of Technology Kanpur; National Health and Medical Research Council; Japan Agency for Medical Research and Development","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Receptor; Arrestin; Transmembrane protein; Cell biology; Biology; G protein; Functional selectivity; Neuroscience; Transmembrane domain; Signal transduction; Biochemistry","score_opus":0.01511924223217496,"score_gpt":0.21895950900844827,"score_spread":0.20384026677627332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3128946477","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98883444,0.00277626,0.0042120744,0.00017772529,0.0029550432,0.0007783031,0.00010336371,0.00014215823,0.000020627524],"genre_scores_gemma":[0.9898437,0.0017400192,0.0058866288,0.00030827857,0.0016509902,0.00018982028,0.000014855178,0.00027962704,0.00008604268],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9954215,0.00024891246,0.00089657767,0.001970406,0.00053748774,0.00092510553],"domain_scores_gemma":[0.9963849,0.00004977203,0.00050565985,0.0019039577,0.00062885287,0.0005268685],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0007520788,0.00094652444,0.0009537132,0.00017768455,0.00029231017,0.0002912202,0.00088526704,0.0014334174,0.0006664654],"category_scores_gemma":[0.0003389864,0.0010261931,0.0005625913,0.00041142124,0.00015827549,0.0000143354955,0.0010302162,0.0008889289,0.00005993033],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010677635,0.000114848975,0.0008244023,0.0003059,0.00033356063,0.0000668487,0.000014806993,0.00040702472,0.99722785,0.000023589491,0.00056454464,0.00000984728],"study_design_scores_gemma":[0.00089534436,0.0001520961,0.0020767257,0.00038101428,0.00016201529,1.4738687e-7,0.000008900416,0.0003600515,0.9751756,6.1641003e-7,0.019537207,0.0012502404],"about_ca_topic_score_codex":0.00008382946,"about_ca_topic_score_gemma":0.000032984146,"teacher_disagreement_score":0.022052208,"about_ca_system_score_codex":0.00018846535,"about_ca_system_score_gemma":0.0013548663,"threshold_uncertainty_score":0.9998629},"labels":[],"label_agreement":null},{"id":"W3129749447","doi":"10.1016/j.bpj.2020.11.969","title":"Probing Allostery in Oligomeric M2 Receptors using smFRET","year":2021,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Allosteric regulation; G protein-coupled receptor; Förster resonance energy transfer; Chemistry; Ligand (biochemistry); Cysteine; Receptor; Biochemistry; Biophysics; Biology; Fluorescence; Enzyme","score_opus":0.0178817596907275,"score_gpt":0.2556124330474702,"score_spread":0.23773067335674272,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3129749447","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99621576,0.0001930903,0.0026900358,0.00007602137,0.0005835855,0.000045202723,0.0000017013778,0.0000039881575,0.00019062392],"genre_scores_gemma":[0.9949302,0.00013202458,0.0034594748,0.00018455985,0.0010593103,0.0000021010765,0.000012627674,0.000023509376,0.00019619815],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989683,0.00010141002,0.00024830754,0.00024123998,0.00015612293,0.00028464285],"domain_scores_gemma":[0.9995729,0.000007422608,0.000088862755,0.00013647023,0.00007901799,0.00011536373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014759586,0.00013341858,0.00017320279,0.000044913082,0.000088563116,0.00007379651,0.0001229848,0.00010773181,0.00015730235],"category_scores_gemma":[0.000034349396,0.00012321271,0.00014438776,0.00017350134,0.000028843755,0.000008426529,0.00008894509,0.0002160161,0.000011756763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023217126,0.00007085521,0.0002965961,0.0000064727287,0.000024214572,0.00005427855,0.000045026325,0.00015915128,0.9973125,0.00005198921,0.000100806574,0.0018549114],"study_design_scores_gemma":[0.00037521083,0.000109291555,0.00012519145,0.000056446508,0.000010757199,0.00023149412,0.00015832338,0.0004686069,0.9949121,0.00011076179,0.0032503817,0.00019143886],"about_ca_topic_score_codex":0.000004834684,"about_ca_topic_score_gemma":0.0000022681033,"teacher_disagreement_score":0.003149575,"about_ca_system_score_codex":0.000035399073,"about_ca_system_score_gemma":0.00012434425,"threshold_uncertainty_score":0.50244683},"labels":[],"label_agreement":null},{"id":"W3130004377","doi":"10.1016/j.cellsig.2021.109947","title":"Subtype-dependent regulation of Gβγ signalling","year":2021,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Heterotrimeric G protein; G protein-coupled receptor; G protein; Effector; Signalling; Biology; Cell biology; Protein subunit; Signal transduction; Gq alpha subunit; Receptor; Computational biology; Gene; Genetics","score_opus":0.031108072066891066,"score_gpt":0.27393277255735426,"score_spread":0.2428247004904632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130004377","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029811915,0.92221653,0.07634003,0.0000017228055,0.00041961248,0.00040750575,0.000022567623,0.000019782452,0.00027411786],"genre_scores_gemma":[0.004065551,0.9900667,0.0021514248,0.000011356003,0.00082604575,0.000035966325,0.0015828989,0.00015446618,0.001105575],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969341,0.0003104048,0.0010691835,0.0008579119,0.00041690283,0.00041148465],"domain_scores_gemma":[0.9982236,0.00006080287,0.0007938375,0.0005468273,0.00024410409,0.00013083768],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007471045,0.0005517591,0.001455296,0.00015849766,0.00011651638,0.00006375764,0.00045512468,0.0007976216,0.0005573793],"category_scores_gemma":[0.000074870564,0.0005369439,0.00096867717,0.00024449348,0.000047427508,0.0000058507526,0.00019135233,0.00034955636,0.00002669027],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010423809,0.000072724244,9.821248e-7,0.0049547143,0.00047528837,0.000024077961,0.000032011463,0.000989187,0.8028882,0.00038632556,0.0000853866,0.19008067],"study_design_scores_gemma":[0.00018417112,0.00012006753,3.975153e-8,0.006294711,0.00063555565,0.000021543168,0.000036956822,0.00015514031,0.4611449,0.000081269296,0.53066134,0.00066430785],"about_ca_topic_score_codex":0.000008254071,"about_ca_topic_score_gemma":0.0000020516138,"teacher_disagreement_score":0.530576,"about_ca_system_score_codex":0.000045611214,"about_ca_system_score_gemma":0.0004057652,"threshold_uncertainty_score":0.99970824},"labels":[],"label_agreement":null},{"id":"W3130480976","doi":"10.1038/s41386-021-00982-y","title":"A versatile GPCR toolkit to track in vivo neuromodulation: not a one-size-fits-all sensor","year":2021,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"Novartis Stiftung für Medizinisch-Biologische Forschung; Fondation pour la Recherche Médicale; Universität Zürich; European Commission; Olga Mayenfisch Stiftung; Novartis Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Neuromodulation; Track (disk drive); Computer science; G protein-coupled receptor; Neuroscience; Computational biology; Psychology; Biology; Medicine; Internal medicine; Receptor; Central nervous system","score_opus":0.02616730232203382,"score_gpt":0.29630145907884825,"score_spread":0.2701341567568144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130480976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99398303,0.00008520427,0.00034120164,0.0019687626,0.001518139,0.0003210935,0.00003048015,0.00003053505,0.0017215472],"genre_scores_gemma":[0.98030204,0.00014045292,0.0016460351,0.015294779,0.0005694527,0.00005756775,0.000020957119,0.00005467938,0.0019140267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979338,0.00027846135,0.00036526637,0.0007898849,0.00018260101,0.00044996152],"domain_scores_gemma":[0.9991883,0.00006636114,0.00007592672,0.0003521202,0.00012341086,0.00019390107],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00015411543,0.00023114235,0.0002654932,0.00007567456,0.00005921502,0.00003552041,0.00022546691,0.00018407252,0.0023318485],"category_scores_gemma":[0.00016307576,0.00027239858,0.00011954566,0.0002825579,0.000028411494,0.0000075636167,0.00012589451,0.000235436,0.00008841409],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004560169,0.0001845247,0.00015056747,0.000012795105,0.000034198114,0.00018634308,0.00010495028,0.0008946029,0.9923691,0.000039690007,0.004002307,0.0015649132],"study_design_scores_gemma":[0.002026189,0.00046307727,0.002645824,0.000008342821,0.000028667017,0.00007585307,0.000035070294,0.00024602798,0.8653181,0.000030371784,0.12883097,0.0002914877],"about_ca_topic_score_codex":0.000008899401,"about_ca_topic_score_gemma":0.000025574509,"teacher_disagreement_score":0.12705097,"about_ca_system_score_codex":0.000022498729,"about_ca_system_score_gemma":0.00008959216,"threshold_uncertainty_score":0.9999728},"labels":[],"label_agreement":null},{"id":"W3131273798","doi":"10.1038/s41467-021-24968-y","title":"Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; McGill University; Université de Montréal; McGill University Health Centre","funders":"Instituto de Salud Carlos III; Canadian Institutes of Health Research; McGill University Health Centre; Réseau Québécois de Recherche sur les Médicaments; McGill University","keywords":"G protein-coupled receptor; Internalization; Endosome; Cell biology; Endocytosis; Receptor; Signal transduction; Protein kinase B; Cell signaling; Biology; Chemistry; Intracellular; Biochemistry","score_opus":0.013351413305697042,"score_gpt":0.2671141787067583,"score_spread":0.25376276540106124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3131273798","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.966369,0.0309978,0.000743197,0.000633416,0.00008730755,0.0000804778,0.00028525424,0.000007114959,0.0007964561],"genre_scores_gemma":[0.9878043,0.0018461621,0.009057526,0.00020969792,0.00009310309,0.000009684886,0.0008502564,0.000010445072,0.000118822536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994508,0.00008506375,0.00014188336,0.00016567358,0.00007569419,0.00008086548],"domain_scores_gemma":[0.9989226,0.000055773828,0.000062666,0.0008204704,0.00010787427,0.000030602485],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006687275,0.000077281395,0.00011329399,0.000018983304,0.00008521909,0.000028023114,0.0002132124,0.00019905933,0.000017608492],"category_scores_gemma":[0.00011836575,0.00007490147,0.000055826727,0.00007437043,0.00006573473,0.0000062401773,0.0003272282,0.00021931245,9.663729e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012340447,0.00006474116,0.0008671557,0.0000029688551,0.000056373316,6.636006e-7,0.000058454112,9.889416e-7,0.99586064,0.0018706023,0.0006556436,0.00054945995],"study_design_scores_gemma":[0.00030846067,0.00003908888,0.0012106239,0.000024627776,0.00003124817,0.0000059586605,0.00019293699,0.000027545397,0.9732395,0.0002067004,0.02461393,0.000099393066],"about_ca_topic_score_codex":0.000059134865,"about_ca_topic_score_gemma":0.0003429139,"teacher_disagreement_score":0.029151637,"about_ca_system_score_codex":0.0000049370983,"about_ca_system_score_gemma":0.00006445494,"threshold_uncertainty_score":0.30543935},"labels":[],"label_agreement":null},{"id":"W3133174712","doi":"10.1038/s41589-021-00907-2","title":"A proteome-wide map of 20(S)-hydroxycholesterol interactors in cell membranes","year":2021,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Northern Alberta Institute of Technology","funders":"National Institute of General Medical Sciences; National Institutes of Health; Foundation for the National Institutes of Health","keywords":"Proteome; Biology; Computational biology; Ligand (biochemistry); Transmembrane protein; Small molecule; Biochemistry; Metabolite; Membrane; Cell biology; Receptor","score_opus":0.004451947635508009,"score_gpt":0.24186565631641654,"score_spread":0.23741370868090853,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133174712","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99571633,0.0029202322,0.0001625023,0.00031608032,0.00028192656,0.00012631543,0.000020897261,0.0000068685267,0.00044884102],"genre_scores_gemma":[0.9976404,0.00006839846,0.0010147063,0.00052702916,0.00014587442,0.000015295289,0.00032611046,0.000016339192,0.00024587638],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998911,0.00007382173,0.00028348473,0.00042035256,0.00006605791,0.0002452474],"domain_scores_gemma":[0.9994642,0.000039685063,0.00009149181,0.00025398418,0.000089555404,0.00006104333],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011121535,0.00016067359,0.0002627711,0.000044412085,0.00001183914,0.0000066645734,0.00020819604,0.0008306672,0.00018014103],"category_scores_gemma":[0.00015709357,0.00014055974,0.00011859581,0.00009615379,0.000061713385,0.0000027415526,0.00013806568,0.00042660898,0.000006556454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071643975,0.00009316101,0.001809659,0.00006885818,0.00001780653,0.000006614267,0.000033546054,0.0000036341123,0.99727696,0.00003751262,0.00028887685,0.0002917537],"study_design_scores_gemma":[0.0005121588,0.00008487623,0.00003936185,0.000026665288,0.000005812958,0.000007951822,0.00004161125,0.000008648036,0.9764576,0.0003379531,0.022332856,0.00014451603],"about_ca_topic_score_codex":0.00000415801,"about_ca_topic_score_gemma":0.000009035298,"teacher_disagreement_score":0.02204398,"about_ca_system_score_codex":0.000012554448,"about_ca_system_score_gemma":0.000053672236,"threshold_uncertainty_score":0.64068663},"labels":[],"label_agreement":null},{"id":"W3134246207","doi":"10.1101/2021.03.05.434048","title":"A genetically encoded fluorescent biosensor for extracellular L-lactate","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre Hospitalier de l’Université de Montréal; University of Alberta; University of Calgary","funders":"","keywords":"Extracellular; Biosensor; Fluorescence; Green fluorescent protein; Cell; Biochemistry; Chemistry; Cell biology; Biology; Biophysics; Gene","score_opus":0.01232054788300416,"score_gpt":0.21934549936606232,"score_spread":0.20702495148305816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3134246207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9154117,0.006324462,0.0751569,0.00012190676,0.0014676811,0.0011446936,0.00026522233,0.000102930426,0.0000044861804],"genre_scores_gemma":[0.9399145,0.0009401379,0.057324998,0.00019832586,0.0010620829,0.00029961893,0.000009489616,0.00021856317,0.000032235293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99648935,0.00015074409,0.00066336634,0.0015725591,0.0003427915,0.0007811881],"domain_scores_gemma":[0.99699855,0.000026962198,0.00034794465,0.0014075479,0.00084612245,0.00037289],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050327095,0.000691141,0.0006161662,0.000119349774,0.00017987814,0.0003053681,0.0005937083,0.0009832438,0.000081542],"category_scores_gemma":[0.00029598316,0.000757506,0.0004851123,0.00015965263,0.00007876497,0.000006782658,0.00056531135,0.00043043421,0.000014455512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008319455,0.00015439786,0.00015746843,0.00030023046,0.0002508875,0.000034859488,0.0000053806157,0.00016729832,0.9982762,0.00030657116,0.00025812056,0.0000054039983],"study_design_scores_gemma":[0.0006705725,0.00016392116,0.00043701645,0.00019089172,0.0001406357,4.6578016e-8,0.000006250434,0.0010208269,0.9846984,0.0000022501147,0.011766542,0.0009026095],"about_ca_topic_score_codex":0.0000115374705,"about_ca_topic_score_gemma":0.0000027811664,"teacher_disagreement_score":0.02450283,"about_ca_system_score_codex":0.000066130844,"about_ca_system_score_gemma":0.00073928974,"threshold_uncertainty_score":0.9994876},"labels":[],"label_agreement":null},{"id":"W3135158155","doi":"10.4230/lipics.dice.2016.1","title":"Normal form systems generated by single connectives have mutually equivalent efficiency","year":2018,"lang":"en","type":"preprint","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Future Earth","funders":"","keywords":"Equivalence (formal languages); Formalism (music); Factorization; Mathematics; Logical equivalence; Boolean function; Discrete mathematics; Pure mathematics; Algorithm","score_opus":0.013542850872266357,"score_gpt":0.2249115946940147,"score_spread":0.21136874382174833,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3135158155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.65566623,0.0036182008,0.32461372,0.00036721054,0.0006171911,0.00055253645,0.00017731807,0.0000821176,0.014305491],"genre_scores_gemma":[0.9841534,0.00042761932,0.0053379703,0.000054303062,0.00013732631,0.00008413138,0.0020473148,0.00006694001,0.0076910327],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9957915,0.0019427793,0.00053078873,0.00092935533,0.00035362478,0.00045193266],"domain_scores_gemma":[0.995836,0.00013600648,0.0004839239,0.0013705498,0.0019867832,0.00018669943],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0027309048,0.00039070938,0.0003493124,0.00008837088,0.00033948597,0.00039069753,0.0009470918,0.00049793127,0.00015980635],"category_scores_gemma":[0.0005474663,0.00040141775,0.00021331516,0.00011294729,0.00020436336,0.000011280021,0.0011727033,0.00031117047,0.00001649082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026834374,0.00045430133,0.00017374437,0.000110218,0.00012506511,0.000001718495,0.0015323334,0.00024316592,0.9897146,0.00196966,0.003461317,0.0021870267],"study_design_scores_gemma":[0.00043830238,0.0000059410513,0.000026074978,0.00049636106,0.00003526007,0.000010037835,0.00021657137,0.01132833,0.9712096,0.00018681352,0.015551268,0.00049547164],"about_ca_topic_score_codex":0.00038099414,"about_ca_topic_score_gemma":0.0002066741,"teacher_disagreement_score":0.32848713,"about_ca_system_score_codex":0.00008371935,"about_ca_system_score_gemma":0.00023062984,"threshold_uncertainty_score":0.9998438},"labels":[],"label_agreement":null},{"id":"W3136470136","doi":"10.1021/acschembio.1c00036","title":"The Promise and Peril of Chemical Probe Negative Controls","year":2021,"lang":"en","type":"letter","venue":"ACS Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Wellcome Trust","keywords":"Phenotype; Chemical biology; Ligand (biochemistry); Chemical modification; Computational biology; Target protein; Gene; Loss function; Chemistry; Function (biology); Biology; Biophysics; Genetics; Biochemistry; Receptor","score_opus":0.00968408167549901,"score_gpt":0.23258081880756995,"score_spread":0.22289673713207095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3136470136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8310937,0.01291846,0.00030086364,0.15224454,0.0006945064,0.0013575805,0.000300855,0.00003496571,0.0010544807],"genre_scores_gemma":[0.7756949,0.0027127415,0.0038448805,0.2004347,0.009490846,0.0005961889,0.0050766966,0.00021612058,0.0019329034],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99833393,0.00013910711,0.00039428877,0.0006199355,0.000106193365,0.0004065277],"domain_scores_gemma":[0.9989235,0.00020129164,0.00023313882,0.00040503909,0.00017706008,0.000060012153],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00017187445,0.000311064,0.0005056669,0.000016468694,0.000053457563,0.000026295356,0.00035398747,0.0014535723,0.000053614476],"category_scores_gemma":[0.0005222097,0.00021202584,0.00017124621,0.00005150859,0.0005432693,0.0000015837192,0.00033609333,0.00070186425,0.0000018796425],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008056467,0.000015015196,0.000016697715,0.00004477833,0.00016096118,0.0000060839,0.000020131658,2.6228355e-8,0.9548942,0.00013572621,0.043383367,0.001242462],"study_design_scores_gemma":[0.00041383493,0.00010764553,4.7063835e-7,0.000022791306,0.00003520292,0.000025305371,0.000016021932,0.0000026869589,0.7613871,0.0010486085,0.23674789,0.00019244247],"about_ca_topic_score_codex":0.000008263003,"about_ca_topic_score_gemma":5.2407285e-7,"teacher_disagreement_score":0.19350709,"about_ca_system_score_codex":0.000013867423,"about_ca_system_score_gemma":0.00011547667,"threshold_uncertainty_score":0.99984276},"labels":[],"label_agreement":null},{"id":"W3137473376","doi":"10.1016/j.cell.2021.02.041","title":"Delineating the conformational landscape of the adenosine A2A receptor during G protein coupling","year":2021,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":157,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Core Research for Evolutional Science and Technology; National Institute of General Medical Sciences; Université de Sherbrooke; Natural Sciences and Engineering Research Council of Canada; Ministry of Education, Culture, Sports, Science and Technology; Japan Society for the Promotion of Science; Japan Science and Technology Agency; Canadian Institutes of Health Research","keywords":"Heterotrimeric G protein; G protein-coupled receptor; Allosteric regulation; Biology; G protein; Adenosine A2A receptor; Biophysics; Structural biology; Nuclear magnetic resonance spectroscopy; Biochemistry; Adenosine receptor; Signal transduction; Agonist; Receptor; Stereochemistry; Chemistry","score_opus":0.0060585543396144,"score_gpt":0.1971349092627096,"score_spread":0.19107635492309522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3137473376","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997214,0.00079017726,0.00097610475,0.00014414947,0.00011902976,0.000115248375,0.000008570127,0.0000037029836,0.00062901515],"genre_scores_gemma":[0.9975601,0.000029475748,0.0007472753,0.00006564573,0.00019464818,0.000010206359,0.000044638506,0.000009131594,0.0013389218],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994782,0.000020407702,0.00017342693,0.00010864891,0.00011327207,0.000106031286],"domain_scores_gemma":[0.9995664,0.000008719826,0.00009715345,0.000187747,0.00012112439,0.000018875306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013427221,0.00006726173,0.000065680455,0.000006512166,0.00013626207,0.000018314415,0.00013485503,0.000055874803,0.00020761183],"category_scores_gemma":[0.000052772924,0.000041529438,0.00006804207,0.00006321884,0.00002117361,0.0000024665949,0.00009821898,0.00007495409,0.0000045014303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009010011,0.000011321354,0.00016336085,0.000028534932,0.000008830524,1.9810639e-7,0.00005889165,0.0013420162,0.99810445,0.00005730392,0.00016562942,0.00005045935],"study_design_scores_gemma":[0.00022355956,0.00001499807,0.00010614081,0.000029323666,0.0000056444005,0.000003630276,0.00033180165,0.0013559707,0.99476826,0.000012667846,0.0030902724,0.00005770788],"about_ca_topic_score_codex":0.0000023325688,"about_ca_topic_score_gemma":0.000002021802,"teacher_disagreement_score":0.003336161,"about_ca_system_score_codex":0.000004052969,"about_ca_system_score_gemma":0.00006642073,"threshold_uncertainty_score":0.22732039},"labels":[],"label_agreement":null},{"id":"W3138038490","doi":"10.1038/s41598-021-84069-0","title":"Ligand modulation of the conformational dynamics of the A2A adenosine receptor revealed by single-molecule fluorescence","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Process Research Ortech (Canada); Dairy Farmers of Ontario; Becton Dickinson (Canada); Canada Research Chairs; University of Toronto","funders":"U.S. Department of Energy; Laboratory Directed Research and Development; Los Alamos National Laboratory; National Nuclear Security Administration; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Chemistry; Förster resonance energy transfer; G protein-coupled receptor; Ligand (biochemistry); Biophysics; Adenosine receptor; Transmembrane domain; Adenosine A2A receptor; Stereochemistry; Receptor; Fluorescence; Agonist; Biochemistry; Biology","score_opus":0.006679640087913338,"score_gpt":0.2058106351546452,"score_spread":0.19913099506673188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138038490","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957089,0.0001894254,0.0015158763,0.00020078976,0.0019266924,0.00014566859,0.000021684391,0.0000026565024,0.00028835313],"genre_scores_gemma":[0.9971212,0.0000054813086,0.00049937784,0.000023706658,0.000028336697,0.0000031170134,0.00024782383,0.000006599383,0.0020643617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988455,0.00005152967,0.00039123,0.00025351797,0.0003491632,0.00010902776],"domain_scores_gemma":[0.99862415,0.0000062501176,0.00041445854,0.0005610661,0.0003675625,0.000026536478],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040761128,0.00007528291,0.00009845116,0.000014954724,0.00014321586,0.00004556423,0.00015137832,0.00007350051,0.000053702555],"category_scores_gemma":[0.00022094733,0.00005015401,0.00010978682,0.0002352539,0.00016233513,0.000008720667,0.00012325065,0.000049866994,4.6270034e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000043587715,0.000035782254,0.0011662251,0.000016809896,0.0000104374385,5.089841e-7,0.00004520314,0.00016676736,0.9943379,0.000106330546,0.0038304327,0.00027920576],"study_design_scores_gemma":[0.000071969946,0.00001616467,0.0005109623,0.000045664507,0.000008383428,0.000025614354,0.00006282804,0.0007917455,0.9956575,0.0004138371,0.0023361684,0.00005916453],"about_ca_topic_score_codex":0.000005700014,"about_ca_topic_score_gemma":0.000010672409,"teacher_disagreement_score":0.0018983558,"about_ca_system_score_codex":0.00001681096,"about_ca_system_score_gemma":0.00016734954,"threshold_uncertainty_score":0.2045221},"labels":[],"label_agreement":null},{"id":"W3138913229","doi":"10.3389/fncir.2021.648624","title":"Neuromodulation of Persistent Activity and Working Memory Circuitry in Primate Prefrontal Cortex by Muscarinic Receptors","year":2021,"lang":"en","type":"review","venue":"Frontiers in Neural Circuits","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund","keywords":"Neuroscience; Muscarinic acetylcholine receptor; Prefrontal cortex; Working memory; Neuromodulation; Psychology; Cholinergic; Muscarinic acetylcholine receptor M4; Stimulation; Cognition; Receptor; Medicine; Internal medicine","score_opus":0.025574364389330285,"score_gpt":0.2691246321365066,"score_spread":0.24355026774717634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138913229","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09506776,0.902641,0.0001661076,0.0000028814425,0.0013922368,0.00057125377,0.000027468403,0.000007818302,0.00012345829],"genre_scores_gemma":[0.19778767,0.8015005,0.000066386834,0.0000133212625,0.0000906554,0.00004522376,0.00032884852,0.00006298204,0.00010439939],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975541,0.00038623248,0.0006288125,0.00084415165,0.00021619204,0.00037050145],"domain_scores_gemma":[0.9990864,0.000023662511,0.00041478738,0.00035465285,0.000031574997,0.000088930785],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002909095,0.00041739427,0.0012808297,0.00019690646,0.00004753733,0.00003304136,0.00024552344,0.0005264259,0.000014674663],"category_scores_gemma":[0.00006250474,0.00043938073,0.0004794327,0.00026355896,0.00007423446,0.000013243587,0.00015652877,0.00044084576,2.9645975e-7],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009287934,0.0000717461,0.00043341832,0.0016703854,0.000113929345,0.000011777678,0.00007375202,0.00004092144,0.015142675,0.000001276666,0.0001961066,0.9822347],"study_design_scores_gemma":[0.012611527,0.0043710778,0.00885113,0.06786371,0.0050483877,0.0010313358,0.0033215971,0.009395532,0.03970315,0.00014271669,0.8334609,0.014198885],"about_ca_topic_score_codex":0.000028562337,"about_ca_topic_score_gemma":0.000013713648,"teacher_disagreement_score":0.9680358,"about_ca_system_score_codex":0.00011685167,"about_ca_system_score_gemma":0.00013939598,"threshold_uncertainty_score":0.9998058},"labels":[],"label_agreement":null},{"id":"W3139366101","doi":"10.1016/j.celrep.2021.108862","title":"Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Horizon 2020; Medical Research Council; Canadian Institutes of Health Research; Université de Montréal; Queen's University; Canada Research Chairs; Horizon 2020 Framework Programme; Novo Nordisk Fonden; Queen's University Belfast; NIHR Cambridge Biomedical Research Centre; Fondation Botnar; European Commission; Diabetes UK; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; National Institute for Health and Care Research; American Lebanese Syrian Associated Charities; Lister Institute of Preventive Medicine; Wellcome Trust; Department for the Economy; European Molecular Biology Organization","keywords":"Internalization; Endocytosis; Cell biology; Melanocortin 4 receptor; Biology; Mutation; Intracellular; Receptor; Genetics; Gene; Melanocortin","score_opus":0.009983255968206754,"score_gpt":0.21981447426381176,"score_spread":0.209831218295605,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3139366101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9603272,0.0010140871,0.037901867,0.000012769344,0.00028301912,0.0002059954,0.0000014677719,0.000018844376,0.00023474633],"genre_scores_gemma":[0.9957382,0.0001046088,0.0033151822,0.00003562039,0.00012457972,0.000016922246,0.00035452124,0.000034333483,0.0002760036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855405,0.00011488399,0.00039638643,0.00055506703,0.00015278268,0.000226856],"domain_scores_gemma":[0.99932843,0.000012276582,0.00021609837,0.0003028465,0.00006718022,0.000073181436],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038871364,0.00016895165,0.00019685595,0.000059373935,0.00013464357,0.00004956765,0.000045179077,0.00018860499,0.00005416011],"category_scores_gemma":[0.0000791876,0.0001844973,0.00006576027,0.00012777584,0.000015898873,0.00001084358,0.000072705,0.00009059139,6.510468e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006790273,0.000041440668,0.0020804126,0.000039619197,0.0000119245005,0.00015857814,0.000084672596,0.00053560955,0.9965675,0.000097985394,0.000027350732,0.0003481087],"study_design_scores_gemma":[0.00038254895,0.00005424148,0.0010514872,0.000055842716,0.000021675027,0.00004149405,0.000084188694,0.0009966292,0.99618965,0.0006144857,0.000298964,0.00020876102],"about_ca_topic_score_codex":0.000017949118,"about_ca_topic_score_gemma":0.000040014693,"teacher_disagreement_score":0.035411026,"about_ca_system_score_codex":0.00002177567,"about_ca_system_score_gemma":0.00005218709,"threshold_uncertainty_score":0.7523582},"labels":[],"label_agreement":null},{"id":"W3147531120","doi":"10.1038/s41594-021-00674-7","title":"GPCR activation mechanisms across classes and macro/microscales","year":2021,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":308,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Novo Nordisk Fonden; European Commission; Canadian Institutes of Health Research; American Lebanese Syrian Associated Charities; Novo Nordisk; American Heart Association; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; H. Lundbeck A/S; Lundbeckfonden; National Science Foundation","keywords":"G protein-coupled receptor; Computational biology; Macro; Chemistry; Biology; Cell biology; Computer science; Signal transduction","score_opus":0.003868631346560044,"score_gpt":0.299291084618114,"score_spread":0.2954224532715539,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3147531120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96487683,0.0028666046,0.030964997,0.0004740493,0.00049792376,0.00013582755,0.00006266465,0.000024574498,0.00009653704],"genre_scores_gemma":[0.9877674,0.00012177417,0.009313256,0.0017354203,0.00018158997,0.000010171719,0.0006799093,0.000032635086,0.00015786986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984571,0.00013347257,0.00021290653,0.0006788272,0.000106060324,0.00041167962],"domain_scores_gemma":[0.99929684,0.000013219726,0.000099749144,0.00031059026,0.00018182474,0.00009777695],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010844966,0.0002708909,0.0002422894,0.000029780365,0.00018803967,0.00006556679,0.00017417161,0.00090010674,0.00007294557],"category_scores_gemma":[0.0001460035,0.00023863815,0.00012289268,0.00012183503,0.00011058704,0.0000071729182,0.00025287177,0.00038134478,0.000002112601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042632073,0.0000058394576,0.00016224555,0.000013464398,0.000067563546,0.000014026797,0.000026086202,0.000008205123,0.98020345,0.015707156,0.00008065066,0.003668677],"study_design_scores_gemma":[0.0004336588,0.00014376502,0.00079609005,0.000010988571,0.000014599288,0.00014893405,0.00010974624,0.000028005918,0.9794689,0.013387001,0.005172893,0.00028542883],"about_ca_topic_score_codex":0.000009026235,"about_ca_topic_score_gemma":0.000017651882,"teacher_disagreement_score":0.022890551,"about_ca_system_score_codex":0.000016309375,"about_ca_system_score_gemma":0.000059680653,"threshold_uncertainty_score":0.9731381},"labels":[],"label_agreement":null},{"id":"W3150172400","doi":"10.1002/mds.28564","title":"Spatial Covariance of Cholinergic Muscarinic <scp>M<sub>1</sub></scp>/<scp>M<sub>4</sub></scp> Receptors in Parkinson's Disease","year":2021,"lang":"en","type":"article","venue":"Movement Disorders","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada; NIHR Newcastle Biomedical Research Centre; Newcastle upon Tyne Hospitals NHS Foundation Trust; Newcastle University; University of Cambridge; Cambridge University Hospitals; National Institute for Health and Care Research","keywords":"Basal forebrain; Neuroscience; Cholinergic; Muscarinic acetylcholine receptor; Psychology; Cholinergic neuron; Cognitive decline; Default mode network; Internal medicine; Cognition; Receptor; Endocrinology; Biology; Medicine; Disease; Dementia","score_opus":0.0067416323354300926,"score_gpt":0.21089825417882782,"score_spread":0.20415662184339772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3150172400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98964256,0.0025799237,0.005388531,0.00018422375,0.0009431809,0.0005182615,0.000093329916,0.0000363392,0.00061363896],"genre_scores_gemma":[0.9921335,0.004686024,0.00028534705,0.0014564148,0.0002790308,0.00016329205,0.0006577771,0.000102325976,0.00023629743],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99648064,0.00023466937,0.00078055216,0.0011138024,0.00055211264,0.00083823357],"domain_scores_gemma":[0.9982519,0.00010538705,0.0003697857,0.0007665603,0.00016835325,0.00033798272],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00043548833,0.0005352897,0.0005202429,0.00016173335,0.00014088769,0.00007013238,0.00042799953,0.0003308416,0.000032115928],"category_scores_gemma":[0.00061131857,0.0005995137,0.00040634512,0.00048168816,0.00013566094,0.000024094625,0.00033785458,0.00030236863,0.000021042024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037657548,0.00057418016,0.011610712,0.00011948423,0.00015109638,0.000023280634,0.00019654675,0.003995448,0.9678562,0.00017309717,0.0046943952,0.010567851],"study_design_scores_gemma":[0.0018976806,0.00023873665,0.007113725,0.0000968429,0.00006621556,5.432418e-7,0.00075023033,0.00061484,0.96458644,0.0019456036,0.02248315,0.00020597967],"about_ca_topic_score_codex":0.00010343604,"about_ca_topic_score_gemma":0.0007140698,"teacher_disagreement_score":0.017788755,"about_ca_system_score_codex":0.0000757078,"about_ca_system_score_gemma":0.00032378698,"threshold_uncertainty_score":0.99964565},"labels":[],"label_agreement":null},{"id":"W3155792588","doi":"10.24908/iqurcp.14558","title":"Automated Emotion Classification in Free-moving Rats","year":2021,"lang":"en","type":"article","venue":"Inquiry Queen s Undergraduate Research Conference Proceedings","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"","keywords":"Classifier (UML); Artificial intelligence; Computer science; Artificial neural network; Machine learning; Pattern recognition (psychology)","score_opus":0.08606157070217321,"score_gpt":0.3650904820968671,"score_spread":0.2790289113946939,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3155792588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9775983,0.00035711064,0.004427704,0.013244197,0.0003252184,0.0003882984,0.0000064238757,0.00013376388,0.0035189895],"genre_scores_gemma":[0.9953576,0.0011645549,0.0014892296,0.00007485888,0.00027045695,0.00007189912,0.000099454766,0.000033939137,0.0014380388],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975246,0.00016219159,0.00036089052,0.00072272186,0.000589813,0.00063976157],"domain_scores_gemma":[0.9979533,0.000032550975,0.00009148463,0.00029493487,0.0014695802,0.000158143],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014118779,0.000187292,0.00019853149,0.00023124117,0.0001815691,0.00030568658,0.0003911647,0.0002850728,0.000062451465],"category_scores_gemma":[0.000862998,0.00020184713,0.000064848005,0.00068585254,0.00018911189,0.000046403697,0.0003373275,0.00043371422,0.000028769133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041609354,0.00008673611,0.0010116491,0.00007286617,0.000021018528,0.000013306315,0.00041496978,0.0000074476793,0.9707513,0.017773125,0.0065749637,0.0032310283],"study_design_scores_gemma":[0.0008528791,0.00027803113,0.0019387372,0.0003329403,0.0000079935335,0.000036169837,0.005190556,0.012616531,0.9341158,0.038012356,0.0061855824,0.00043241304],"about_ca_topic_score_codex":0.000093335424,"about_ca_topic_score_gemma":0.000039381783,"teacher_disagreement_score":0.03663547,"about_ca_system_score_codex":0.00011154038,"about_ca_system_score_gemma":0.0005399058,"threshold_uncertainty_score":0.8231087},"labels":[],"label_agreement":null},{"id":"W3158734129","doi":"10.1038/s41598-021-88399-x","title":"Allostery of atypical modulators at oligomeric G protein-coupled receptors","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Receptor; Allosteric regulation; G protein-coupled receptor; Computational biology; Cell biology; Neuroscience; Chemistry; Bioinformatics; Biology; Biochemistry","score_opus":0.008547427833167878,"score_gpt":0.22139119955496997,"score_spread":0.21284377172180208,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158734129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945735,0.00051206676,0.0005709081,0.0000297559,0.0037777675,0.00018638345,0.0000020345512,0.000012504081,0.00033508704],"genre_scores_gemma":[0.9877448,0.000010345199,0.0016911617,0.0000213299,0.000112926646,0.000018015491,0.00020846438,0.000020829402,0.0101721175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814177,0.000051791325,0.00046103055,0.00073278707,0.00034882364,0.0002637878],"domain_scores_gemma":[0.99862814,0.0000044600188,0.00024412967,0.00076232926,0.00024093837,0.00012000813],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053557596,0.00014014158,0.00020457448,0.000052227104,0.00014716902,0.000050430357,0.00010526828,0.00013571931,0.000733356],"category_scores_gemma":[0.00015781504,0.00013059964,0.00017993395,0.0002670925,0.0001378566,0.0000053983185,0.00021618204,0.00005808183,0.000012185972],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025016896,0.000050228824,0.0012656528,0.000021507252,0.00002928797,0.0000633733,0.000036247362,0.00007599302,0.99616235,0.000030286965,0.0017865485,0.00045347615],"study_design_scores_gemma":[0.000099657096,0.00005216285,0.00014312861,0.000024606661,0.00001012715,0.00013201426,0.00004171954,0.00006591291,0.9608206,0.00050705514,0.03795434,0.00014865118],"about_ca_topic_score_codex":0.000006281885,"about_ca_topic_score_gemma":0.000012383083,"teacher_disagreement_score":0.036167793,"about_ca_system_score_codex":0.000022691604,"about_ca_system_score_gemma":0.00017677301,"threshold_uncertainty_score":0.8029734},"labels":[],"label_agreement":null},{"id":"W3159517345","doi":"10.1038/s41422-021-00513-w","title":"Finding a new job: glutamate signaling acts in atrial cardiomyocytes","year":2021,"lang":"en","type":"letter","venue":"Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Montreal Heart Institute","funders":"British Heart Foundation","keywords":"Biology; Glutamate receptor; Neuroscience; Cell biology; Receptor; Genetics","score_opus":0.08270553733537159,"score_gpt":0.3407246320348869,"score_spread":0.25801909469951534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159517345","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78477746,0.0681688,0.0028494655,0.105179265,0.0058525223,0.0035642232,0.000163901,0.00011166011,0.02933273],"genre_scores_gemma":[0.5314845,0.011884655,0.008598295,0.08697796,0.14557193,0.000248814,0.007070456,0.0013094662,0.20685393],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959211,0.0006852404,0.00040594512,0.0009651442,0.00088083313,0.0011417847],"domain_scores_gemma":[0.9987563,0.00014464062,0.000092848335,0.0006206258,0.00022442114,0.00016119985],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.00159999,0.00033868485,0.0004801003,0.000366568,0.00016698104,0.00027363488,0.00062641676,0.0013843079,0.00060321763],"category_scores_gemma":[0.00029689548,0.0003488196,0.0004161504,0.00041578303,0.00006346363,0.0000049909777,0.0005374567,0.0023582214,0.0000708084],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038802118,0.0000070748597,0.000028808905,0.00015329351,0.000057443514,0.00056842394,0.000070712755,0.00015986177,0.67210007,0.000003637345,0.3256394,0.001172485],"study_design_scores_gemma":[0.000490712,0.00010089268,0.000002632595,0.00013590111,0.000012505212,0.0000086323025,0.00007184552,0.000019101692,0.47005108,0.00008520368,0.52874696,0.0002745301],"about_ca_topic_score_codex":0.0002618361,"about_ca_topic_score_gemma":0.00002616744,"teacher_disagreement_score":0.25329295,"about_ca_system_score_codex":0.00011660924,"about_ca_system_score_gemma":0.001085155,"threshold_uncertainty_score":0.9999434},"labels":[],"label_agreement":null},{"id":"W3160758484","doi":"10.1101/2021.05.12.443385","title":"Functional expression of opioid receptors and other human GPCRs in yeast engineered to produce human sterols","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"G protein-coupled receptor; Sterol; DAMGO; Receptor; Biology; Yeast; Agonist; Opioid; Saccharomyces cerevisiae; Chemistry; Biochemistry; Opioid receptor; Cholesterol","score_opus":0.014686804892395357,"score_gpt":0.22442513795212482,"score_spread":0.20973833305972947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3160758484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99691653,0.0006761712,0.0012891256,0.000019924528,0.0005284093,0.00047033065,0.0000673047,0.000027071988,0.0000051397933],"genre_scores_gemma":[0.99645144,0.0000358488,0.0028120982,0.00007944614,0.00039944024,0.00010874634,0.000003946828,0.00008822583,0.000020813195],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980013,0.0001014308,0.0004534889,0.0009134703,0.00023217787,0.0002981385],"domain_scores_gemma":[0.9987224,0.0000058709047,0.00020212866,0.00069343025,0.00021560842,0.00016057555],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036066043,0.0003570466,0.00040084103,0.00017779274,0.00007552757,0.000074548676,0.00023943675,0.0004414378,0.00011692965],"category_scores_gemma":[0.0000747513,0.00038874728,0.00009525336,0.00016653282,0.000043911026,0.000007997273,0.00045480774,0.0002921099,0.0000022405684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028302551,0.000087602304,0.003943606,0.00019521963,0.00004135526,0.0000030215804,0.000022788976,0.00019640234,0.99524975,0.00006251827,0.00016784653,0.0000015658816],"study_design_scores_gemma":[0.00036549708,0.00009768587,0.015731558,0.00046808907,0.000017211303,1.5955477e-8,0.00001394851,0.0000066695998,0.9811451,9.2589727e-7,0.0017646872,0.0003885994],"about_ca_topic_score_codex":0.00003854758,"about_ca_topic_score_gemma":0.00000964432,"teacher_disagreement_score":0.01410466,"about_ca_system_score_codex":0.00003752596,"about_ca_system_score_gemma":0.00015082909,"threshold_uncertainty_score":0.9998565},"labels":[],"label_agreement":null},{"id":"W3161270521","doi":"10.1101/2021.05.17.444454","title":"Decoding Angiotensin II Type 1 Receptor Allosteric Communication to Gq and β-arrestin","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Allosteric regulation; G protein-coupled receptor; Arrestin; Chemistry; Binding site; Receptor; G protein; Biology; Biochemistry","score_opus":0.014296321594520451,"score_gpt":0.22707882267552926,"score_spread":0.2127825010810088,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3161270521","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915823,0.0046050157,0.0021648991,0.00030890363,0.0008184776,0.00040648345,0.000039890918,0.000067145134,0.0000069048733],"genre_scores_gemma":[0.9457444,0.0012230575,0.05203168,0.00047343544,0.00035609683,0.000043049444,0.0000065695335,0.00010217044,0.000019522036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979974,0.00016612654,0.00037561226,0.00089271885,0.00018980786,0.00037835608],"domain_scores_gemma":[0.99776757,0.00001925909,0.00021324102,0.0012158856,0.0005159297,0.0002681266],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004239109,0.00040452371,0.00038590963,0.00011086077,0.00026105164,0.00022454093,0.0004147449,0.000542244,0.0000744715],"category_scores_gemma":[0.0002631148,0.00046453968,0.00010309169,0.00025558812,0.000052693413,0.000009966485,0.0015828646,0.00035314437,0.000014316559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035786845,0.000040814863,0.0006233523,0.00005635181,0.00008578169,0.000005231061,0.000021573293,0.000057271503,0.9981116,0.000050982995,0.00089751085,0.000013740736],"study_design_scores_gemma":[0.00023228918,0.0001468057,0.0028670118,0.00037274507,0.000055643228,6.177881e-8,0.000013586904,0.00013901624,0.97680384,7.951816e-7,0.018723398,0.0006447943],"about_ca_topic_score_codex":0.000043362117,"about_ca_topic_score_gemma":0.000009015387,"teacher_disagreement_score":0.049866784,"about_ca_system_score_codex":0.000051484163,"about_ca_system_score_gemma":0.00028440612,"threshold_uncertainty_score":0.99978065},"labels":[],"label_agreement":null},{"id":"W3161387710","doi":"10.1101/2021.05.18.444749","title":"Humanized substitutions of <i>Vmat1</i> in mice alter amygdala-dependent behaviors associated with the evolution of anxiety","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Institute of Genetics; National Center of Neurology and Psychiatry; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Monoaminergic; Amygdala; Anxiogenic; Neuroscience; Monoamine neurotransmitter; Biology; Psychology; Anxiety; Genetics; Serotonin; Anxiolytic; Psychiatry","score_opus":0.007337452428203759,"score_gpt":0.20449671580602172,"score_spread":0.19715926337781794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3161387710","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937854,0.001310499,0.003965803,0.000026688784,0.00027025337,0.00046261962,0.00015308219,0.000020499225,0.0000051788843],"genre_scores_gemma":[0.99867463,0.00018996235,0.00088626426,0.00002636399,0.00007667496,0.00008093701,0.0000051974794,0.000053257758,0.0000067286633],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980372,0.00021310929,0.0005094021,0.0006081781,0.00032816041,0.0003039577],"domain_scores_gemma":[0.998076,0.000018512425,0.0005696949,0.0007197828,0.0005466468,0.000069356836],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057906384,0.00032372947,0.00045452823,0.0001028383,0.00008654429,0.000042647334,0.00041301394,0.00047856287,0.000028345288],"category_scores_gemma":[0.000101961436,0.00027765808,0.00017252458,0.00030571356,0.00014962947,0.000009613846,0.00029449337,0.00039477478,7.187555e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040080766,0.00020733346,0.008392707,0.00007558235,0.00014169951,0.000004299569,0.000019892406,0.0007770346,0.99015635,0.00016572555,0.000018914963,3.618383e-7],"study_design_scores_gemma":[0.0006037854,0.00007280145,0.02787242,0.00031812568,0.00014040864,2.4509204e-8,0.000046947087,0.00006256896,0.97052294,5.113782e-7,0.000053702563,0.00030576106],"about_ca_topic_score_codex":0.0002526994,"about_ca_topic_score_gemma":0.00017563828,"teacher_disagreement_score":0.019633425,"about_ca_system_score_codex":0.00014833309,"about_ca_system_score_gemma":0.0006237263,"threshold_uncertainty_score":0.9999676},"labels":[],"label_agreement":null},{"id":"W3161797978","doi":"10.1073/pnas.2025846118","title":"BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G <sub>q</sub> activation at early endosomes","year":2021,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Svenska Sällskapet för Medicinsk Forskning; National Institute of General Medical Sciences; Canada Research Chairs; Government of Canada","keywords":"Endosome; Endocytosis; G protein-coupled receptor; Cell biology; Effector; Chromosomal translocation; Receptor; Signal transduction; Transport protein; Chemistry; Compartment (ship); Mechanism (biology); G protein; Biology; Biochemistry; Intracellular","score_opus":0.016541071538761318,"score_gpt":0.24949009837474465,"score_spread":0.23294902683598334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3161797978","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987289,0.00020133714,0.00003413084,0.0007235502,0.000023408165,0.0001578718,0.000018206938,0.0000067438573,0.0001058881],"genre_scores_gemma":[0.99919516,0.00009374063,0.000472481,0.00012076923,0.00007083943,0.0000152067705,0.000006424521,0.00000651626,0.000018875138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987546,0.00002415453,0.00022748008,0.00028672247,0.0005784339,0.0001285841],"domain_scores_gemma":[0.9993286,0.00009023213,0.00024691227,0.00001124765,0.0002840281,0.000038975326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068865344,0.00010502921,0.00013024351,0.000075955235,0.00017039348,0.000025327176,0.00020585478,0.00013343636,0.0000065337194],"category_scores_gemma":[0.0005049161,0.000080562066,0.00006861233,0.000365646,0.00021870402,0.000032561533,0.00005375545,0.00008487784,4.788186e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032623004,0.000025202698,0.0013884581,0.000049525348,0.000019657842,6.626163e-9,0.00004487067,0.00006786761,0.9974746,0.00030015106,0.000033606728,0.00056342466],"study_design_scores_gemma":[0.00035768969,0.000077213685,0.009987841,0.00007156063,0.000011368121,0.0000032363585,0.000034358738,0.00062753016,0.988218,0.00048618615,0.000039549304,0.00008544832],"about_ca_topic_score_codex":0.0000030027056,"about_ca_topic_score_gemma":1.4191986e-7,"teacher_disagreement_score":0.009256588,"about_ca_system_score_codex":0.00002153452,"about_ca_system_score_gemma":0.000053321564,"threshold_uncertainty_score":0.32852256},"labels":[],"label_agreement":null},{"id":"W3162097501","doi":"10.1101/2021.05.13.444094","title":"Mice exhibit stochastic and efficient action switching during probabilistic decision making","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; National Science Foundation","keywords":"Action selection; Task (project management); Action (physics); Set (abstract data type); Probabilistic logic; Inference; Computer science; Markov decision process; Reinforcement learning; Artificial intelligence; Bayesian inference; Representation (politics); Bayesian probability; Machine learning; Markov process; Mathematics; Psychology; Statistics; Perception; Economics","score_opus":0.010477147462367385,"score_gpt":0.2311025341994644,"score_spread":0.220625386737097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3162097501","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8917495,0.0019879905,0.104651265,0.000013958985,0.0009997018,0.00049789285,0.000021694355,0.00007652394,0.0000014904604],"genre_scores_gemma":[0.99009174,0.00013917348,0.008954964,0.00004547123,0.0005612183,0.00007943577,9.631476e-7,0.0001246645,0.0000023414943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9971472,0.00011626474,0.0005071701,0.0013733356,0.00034952574,0.0005065263],"domain_scores_gemma":[0.998275,0.000045250108,0.0003544811,0.0008046436,0.000328378,0.00019225161],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046028759,0.00053276983,0.0004435338,0.00015865156,0.00030573166,0.00036702817,0.0002925138,0.0006024406,0.00003097543],"category_scores_gemma":[0.00043731518,0.0005870879,0.0001623998,0.0001856724,0.00004650019,0.000010689736,0.00086864684,0.00055791484,0.0000048741626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007614547,0.000067708315,0.00014276644,0.00037505728,0.00008092148,0.000022195969,0.000013820145,0.012546049,0.9866168,0.000036526988,0.0000049053665,0.000017113049],"study_design_scores_gemma":[0.00059329736,0.00007259152,0.0077015134,0.0017168476,0.00014076899,4.3445218e-7,0.000027191523,0.0073572774,0.9813526,0.0000043278537,0.00006322549,0.0009698979],"about_ca_topic_score_codex":0.000012989191,"about_ca_topic_score_gemma":0.0000057773227,"teacher_disagreement_score":0.098342285,"about_ca_system_score_codex":0.00011914734,"about_ca_system_score_gemma":0.00029659463,"threshold_uncertainty_score":0.99965805},"labels":[],"label_agreement":null},{"id":"W3162686655","doi":"10.1107/s0108767320098153","title":"B-factor analysis suggests that <scp>L</scp>-lysine and <i>R</i>,<i>R</i>-bis-lysine allosterically inhibit Cj.DHDPS enzyme by decreasing its protein dynamics","year":2020,"lang":"en","type":"article","venue":"Acta Crystallographica Section A Foundations and Advances","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Lysine; Enzyme; Chemistry; Allosteric regulation; Biochemistry; Amino acid","score_opus":0.010006178383967803,"score_gpt":0.23128547498631988,"score_spread":0.22127929660235207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3162686655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9581371,0.0023810817,0.03763047,0.0010102037,0.00007412065,0.0003685163,0.00011472367,0.000061555,0.00022222515],"genre_scores_gemma":[0.99300486,0.0029241466,0.0023541637,0.00046914318,0.00014679441,0.000036242895,0.00080927,0.000035097044,0.00022025905],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99823505,0.00010566646,0.0003612665,0.000738798,0.00023686168,0.00032238656],"domain_scores_gemma":[0.999011,0.000060340455,0.00027517503,0.00020170612,0.00016327992,0.0002885011],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001381285,0.00032609334,0.00036039503,0.0002019206,0.00042615112,0.00028166032,0.00013535406,0.00019239738,0.000052161464],"category_scores_gemma":[0.00020520465,0.00031152164,0.0001778454,0.00094384403,0.00014584685,0.00009793194,0.00012103768,0.00018968881,2.7955804e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035446992,0.000069197406,0.0021748487,0.000044572287,0.0003427568,0.000001708322,0.00009099503,0.000048060396,0.99569225,0.0000921196,0.00011337243,0.0012946589],"study_design_scores_gemma":[0.0028464997,0.0023827257,0.00349211,0.00012340912,0.0012913939,0.000082594204,0.0027243108,0.011904943,0.1327888,0.00064870133,0.8404388,0.0012757394],"about_ca_topic_score_codex":0.000027763637,"about_ca_topic_score_gemma":0.00022651999,"teacher_disagreement_score":0.8629035,"about_ca_system_score_codex":0.000016228392,"about_ca_system_score_gemma":0.000043293483,"threshold_uncertainty_score":0.99993366},"labels":[],"label_agreement":null},{"id":"W3163464248","doi":"10.1016/j.ymeth.2021.05.002","title":"In vivo detection of GPCR-dependent signaling using fiber photometry and FRET-based biosensors","year":2021,"lang":"en","type":"article","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Kyoto University; Weston Brain Institute","keywords":"Förster resonance energy transfer; Biosensor; Intracellular; Biology; Biophysics; Computational biology; Cell biology; Fluorescence; Biochemistry; Physics","score_opus":0.02463926221747055,"score_gpt":0.3348966490087738,"score_spread":0.31025738679130327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3163464248","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.83114034,0.0009842828,0.16762537,0.000006524938,0.00012808296,0.00005167053,0.0000044768553,0.0000032776734,0.000056012384],"genre_scores_gemma":[0.7718107,0.000025344816,0.2279112,0.000060202965,0.000054388864,0.000002793236,0.0000026199461,0.000014533546,0.00011820374],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990112,0.00030380228,0.00020277222,0.000258339,0.000086547574,0.00013729784],"domain_scores_gemma":[0.9996298,0.000044456054,0.00007272646,0.00015018568,0.0000636911,0.00003917152],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067067146,0.00009852419,0.00016363584,0.00008626418,0.000033943797,0.000013248289,0.000043522858,0.0001414648,0.00023880275],"category_scores_gemma":[0.00011512022,0.00010159093,0.00006113111,0.00017539425,0.000023282524,0.000003113671,0.000044053053,0.00007232995,3.4206525e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025385885,0.000019647267,0.00012914358,0.000028490445,0.000015533973,0.0000055284995,0.000022705131,0.00079858437,0.9941199,0.0000030305434,0.0000016085253,0.004830464],"study_design_scores_gemma":[0.0003249708,0.00005688437,0.00002647182,0.000022405608,0.000014694226,0.000011947159,0.00010226082,0.002821221,0.9956691,0.00008317473,0.00075345265,0.000113368755],"about_ca_topic_score_codex":0.000049945505,"about_ca_topic_score_gemma":0.000008943065,"teacher_disagreement_score":0.060285844,"about_ca_system_score_codex":0.00001385162,"about_ca_system_score_gemma":0.000041594165,"threshold_uncertainty_score":0.4142758},"labels":[],"label_agreement":null},{"id":"W3164498945","doi":"10.1016/j.sbi.2021.04.006","title":"Illuminating the complexity of GPCR pathway selectivity – advances in biosensor development","year":2021,"lang":"en","type":"review","venue":"Current Opinion in Structural Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"Canadian Institutes of Health Research; Svenska Sällskapet för Medicinsk Forskning; Canada Excellence Research Chairs, Government of Canada; Canada Research Chairs","keywords":"G protein-coupled receptor; Functional selectivity; Drug discovery; Computational biology; Signal transduction; Drug development; Biology; Neuroscience; Drug; Cell biology; Bioinformatics; Pharmacology","score_opus":0.10249245677379552,"score_gpt":0.39097051347182793,"score_spread":0.2884780566980324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3164498945","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004120918,0.9926075,0.00009839816,0.0000067322185,0.0026620831,0.0004116971,0.00006595075,0.00000440798,0.000022317532],"genre_scores_gemma":[0.010615487,0.98731387,0.0005592729,0.000003068353,0.00027740432,0.00006265829,0.001147168,0.000017511305,0.0000035642431],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99767655,0.00057207455,0.0007726712,0.000561269,0.0000928931,0.00032456804],"domain_scores_gemma":[0.9991105,0.000073793286,0.00044950008,0.00025365528,0.00007828984,0.000034254623],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036227942,0.00034067017,0.0009693444,0.00011111193,0.00006909839,0.0000102489075,0.00033088122,0.00031530723,0.000030478206],"category_scores_gemma":[0.00015112481,0.00022482155,0.00020679785,0.0002910443,0.0002637036,0.0000046669593,0.00025421495,0.00037612751,0.0000010269725],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000055976584,0.000018841145,0.00014113568,0.0023992744,0.000023617915,2.322866e-7,0.000058991624,0.0000035512223,0.0013004338,0.0017102829,0.000007957783,0.9943301],"study_design_scores_gemma":[0.00021128454,0.000075128424,0.00007775479,0.0032238022,0.000009375123,0.0000186561,0.000058969348,0.000010812915,0.0045350706,0.00025485703,0.99117285,0.00035142523],"about_ca_topic_score_codex":0.000010203436,"about_ca_topic_score_gemma":0.000035923298,"teacher_disagreement_score":0.9939787,"about_ca_system_score_codex":0.00005984017,"about_ca_system_score_gemma":0.0003015825,"threshold_uncertainty_score":0.9167957},"labels":[],"label_agreement":null},{"id":"W3165836291","doi":"10.1111/bph.15573","title":"The anomalous pharmacology of fentanyl","year":2021,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":136,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Medical Research Council Canada","keywords":"Fentanyl; Opioid; Morphine; (+)-Naloxone; Pharmacology; Medicine; Opioid overdose; Anesthesia; Internal medicine; Receptor","score_opus":0.020532827898945914,"score_gpt":0.33640188607574606,"score_spread":0.31586905817680017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3165836291","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010783881,0.993158,0.00013455529,0.000040218914,0.00517042,0.0002664353,0.00005033688,0.0000026882417,0.000098981516],"genre_scores_gemma":[0.00063494174,0.9958267,0.00023072331,0.00015209593,0.002645405,0.000019771205,0.0000413523,0.00005568134,0.00039330547],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969553,0.00087195943,0.0012873303,0.00028736654,0.00021021749,0.00038783767],"domain_scores_gemma":[0.9976121,0.00015736674,0.0015464876,0.00010977154,0.0004518106,0.00012243364],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000941994,0.00028479853,0.0014182172,0.00008467176,0.00016055618,0.000042479704,0.0007630697,0.0004233199,0.00080382515],"category_scores_gemma":[0.00007612077,0.00024715808,0.0010201263,0.0001613524,0.00019245523,0.0000049767136,0.00022176732,0.0006523148,0.000003864067],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041560248,0.00013623522,5.673955e-7,0.00085258734,0.001560674,0.0007868781,0.000007015305,0.0000050902936,0.08265692,0.000014707205,0.07290981,0.841028],"study_design_scores_gemma":[0.0006548701,0.00036617342,2.7131298e-7,0.0010566971,0.0012233503,0.010919949,0.000025034855,0.0000010967652,0.035695318,0.00000776833,0.9498458,0.00020370711],"about_ca_topic_score_codex":0.000006081518,"about_ca_topic_score_gemma":0.0000041680155,"teacher_disagreement_score":0.87693596,"about_ca_system_score_codex":0.000043253298,"about_ca_system_score_gemma":0.00083013123,"threshold_uncertainty_score":0.9999981},"labels":[],"label_agreement":null},{"id":"W3166045787","doi":"10.1016/j.sbi.2021.05.001","title":"Advances in the study of GPCRs by 19F NMR","year":2021,"lang":"en","type":"review","venue":"Current Opinion in Structural Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Chemistry; Relaxation (psychology); Fluorine-19 NMR; Biophysics; Signal transduction; Nuclear magnetic resonance spectroscopy; Stereochemistry; Biochemistry; Biology","score_opus":0.05620467617489396,"score_gpt":0.4104972779493392,"score_spread":0.35429260177444527,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3166045787","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0041792863,0.99228144,0.000019508449,0.0000044537137,0.0027618674,0.0006464977,0.00008080089,0.0000024189583,0.00002371646],"genre_scores_gemma":[0.006100156,0.991735,0.000018279448,0.000004554643,0.00031119568,0.00010633772,0.0017066183,0.000014726352,0.0000031251727],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99772733,0.0007010296,0.00068927876,0.0005301417,0.0000988572,0.00025337172],"domain_scores_gemma":[0.9992075,0.000060836872,0.00032211308,0.0003460753,0.000037414324,0.000026055886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025596228,0.00031115365,0.0009095293,0.00009167979,0.000032886957,0.000011446724,0.00049836416,0.00028710594,0.000041973737],"category_scores_gemma":[0.00006351285,0.00019306825,0.00019290466,0.00024721483,0.00006598739,0.000003698203,0.00015528804,0.00033946708,9.678829e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007989956,0.00007624809,0.00021460875,0.0015114392,0.00002652881,3.9280397e-7,0.00010194241,0.0000046665828,0.0002445628,0.00030484548,0.00026079622,0.99724597],"study_design_scores_gemma":[0.00033069344,0.00036456567,0.000009490294,0.0012141513,0.000022055468,0.00001069727,0.00032150594,0.0000018697917,0.000051739044,0.000083776,0.99735713,0.00023234916],"about_ca_topic_score_codex":0.000015128584,"about_ca_topic_score_gemma":0.000012965136,"teacher_disagreement_score":0.9970963,"about_ca_system_score_codex":0.000018459434,"about_ca_system_score_gemma":0.00007751747,"threshold_uncertainty_score":0.78730947},"labels":[],"label_agreement":null},{"id":"W3166935519","doi":"10.1096/fasebj.2021.35.s1.02524","title":"Hierarchical Arrangement of Contractile Mechanisms in Resistance Arteries","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Calphostin C; Myograph; G protein-coupled receptor; Calphostin; Protein kinase C; Biophysics; Chemistry; Cell biology; Phenylephrine; Mesenteric arteries; Biology; Endocrinology; Internal medicine; Signal transduction; Contraction (grammar); Artery; Medicine","score_opus":0.010446449234413948,"score_gpt":0.23403682845501203,"score_spread":0.22359037922059807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3166935519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97110724,0.0010620937,0.026087867,0.00054303225,0.0002419104,0.000053244738,0.000007996161,0.0000017711656,0.0008948592],"genre_scores_gemma":[0.99644375,0.00025365787,0.002396849,0.00016514097,0.0001279134,0.000003200935,0.000006825685,0.000007480333,0.00059515703],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992954,0.000116189236,0.00020564861,0.00010265883,0.00013687892,0.00014323856],"domain_scores_gemma":[0.9996409,0.000016071535,0.00008877142,0.0001476142,0.00006635947,0.00004029766],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036760262,0.000067238376,0.00010999762,0.000018344836,0.0000698772,0.000024560883,0.00012182935,0.000046701047,0.00024499823],"category_scores_gemma":[0.000050402425,0.000048307007,0.00007279331,0.000051120587,0.00003522249,0.0000030055537,0.00003631412,0.00014897391,0.0000015003443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093334915,0.000033030577,0.00004164719,0.000004881288,0.000022303302,0.000025562877,0.00009972221,0.000036279882,0.9967982,0.0019902424,0.00020591867,0.00064887386],"study_design_scores_gemma":[0.0003614082,0.000063051935,0.0001962855,0.00003109137,0.00000754293,0.0000668594,0.00044761994,0.00001309799,0.98940724,0.0060115703,0.0033353977,0.00005883399],"about_ca_topic_score_codex":0.0000015451083,"about_ca_topic_score_gemma":0.000040621217,"teacher_disagreement_score":0.02533655,"about_ca_system_score_codex":0.000008729466,"about_ca_system_score_gemma":0.00007759478,"threshold_uncertainty_score":0.2682559},"labels":[],"label_agreement":null},{"id":"W3167271619","doi":"10.1096/fasebj.2021.35.s1.02463","title":"Receptor Endocytosis as a Mechanism of Biased Agonism at CXCR3","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"G protein-coupled receptor; Internalization; Cell biology; Endosome; Chemokine receptor; Functional selectivity; Biology; Endocytic cycle; Chemistry; Arrestin; Receptor; Signal transduction; Endocytosis; Chemokine; Biochemistry; Intracellular","score_opus":0.014518941278916706,"score_gpt":0.2382146053243841,"score_spread":0.2236956640454674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3167271619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929045,0.0011614814,0.0038566987,0.0003596045,0.000556356,0.000074594376,0.000022648905,0.0000057850357,0.0010583381],"genre_scores_gemma":[0.9938819,0.0009039208,0.0014946854,0.00043769274,0.0004382589,0.000004901662,0.000036692894,0.000024820547,0.0027771413],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988279,0.00018454084,0.0002903007,0.00019445909,0.00024999754,0.00025280655],"domain_scores_gemma":[0.99917066,0.000027168146,0.00020060247,0.0003061386,0.00017476952,0.000120639015],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004291912,0.00014179503,0.00017939812,0.00003100216,0.0002596866,0.000041428648,0.00025557543,0.00011119435,0.0022185221],"category_scores_gemma":[0.00012413891,0.00010200813,0.00024469764,0.00009122931,0.000045331406,0.000003901393,0.00015367319,0.00017523232,0.000046185538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007983507,0.00003557191,0.00002085704,0.000005525061,0.0001040999,0.00001983585,0.00010758429,0.000028878108,0.9966587,0.001021246,0.0010276751,0.0008902225],"study_design_scores_gemma":[0.0005601266,0.00022637661,0.0000069740577,0.000027531414,0.00003770942,0.00057296694,0.00032526776,0.000026127975,0.98922276,0.0012527425,0.007615934,0.00012546401],"about_ca_topic_score_codex":0.000008727569,"about_ca_topic_score_gemma":0.000005861019,"teacher_disagreement_score":0.0074358904,"about_ca_system_score_codex":0.000027585873,"about_ca_system_score_gemma":0.00018106622,"threshold_uncertainty_score":0.9986936},"labels":[],"label_agreement":null},{"id":"W3167531242","doi":"10.1096/fasebj.2021.35.s1.01938","title":"Sympathetic and Parasympathetic Regulation of NF‐κB by GPCRs through the modulation of interactions between p65/RelA and the β‐arrestins","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"National Institute of General Medical Sciences","keywords":"Muscarinic acetylcholine receptor; G protein-coupled receptor; Receptor; Arrestin; Immune system; Parasympathetic nervous system; Cell biology; Cholinergic; Biology; Signal transduction; Neuroscience; Autonomic nervous system; Chemistry; Endocrinology; Internal medicine; Medicine; Immunology","score_opus":0.012302365742868627,"score_gpt":0.24463812648817812,"score_spread":0.23233576074530948,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3167531242","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98583585,0.0017553066,0.011231743,0.0008492872,0.00009301324,0.000094537165,0.000010448743,0.0000015167154,0.00012831065],"genre_scores_gemma":[0.9989026,0.00058297685,0.0001992672,0.000041390453,0.00011600909,0.0000028116463,0.000015833202,0.000008590337,0.00013049386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999162,0.00026079768,0.00025455366,0.000102952,0.00012752878,0.00009214148],"domain_scores_gemma":[0.9993476,0.00010757881,0.00023650836,0.0001872633,0.000095635485,0.000025411251],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046249348,0.00008194212,0.00012611564,0.000011360149,0.00019481925,0.000031628817,0.00010164834,0.000047634414,0.000038366343],"category_scores_gemma":[0.00007471018,0.00004147157,0.000074258765,0.00005994851,0.00019872875,0.000008683205,0.00005459286,0.000141812,2.688496e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002742007,0.0000146114535,0.00067467673,0.0000061144,0.00007007951,2.6881997e-7,0.0010202496,0.0006887162,0.9940498,0.0008075306,0.00010283231,0.0025377378],"study_design_scores_gemma":[0.0007401273,0.00010342175,0.0022696836,0.00006205887,0.00013779134,0.00016416637,0.0013188767,0.0017551311,0.9839855,0.0086409515,0.0007426284,0.000079702506],"about_ca_topic_score_codex":0.00001865544,"about_ca_topic_score_gemma":0.0000044958083,"teacher_disagreement_score":0.01306679,"about_ca_system_score_codex":0.000005330223,"about_ca_system_score_gemma":0.000030247906,"threshold_uncertainty_score":0.16911615},"labels":[],"label_agreement":null},{"id":"W3167896873","doi":"10.1096/fasebj.2021.35.s1.01814","title":"Selective or Specific M1 Muscarinic Receptor Antagonists Exhibit Biased Agonism at the M1 Receptor via β‐arrestin Signaling","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Arrestin; Muscarinic acetylcholine receptor; Chemistry; Muscarine; Pharmacology; Agonist; Muscarinic acetylcholine receptor M3; Receptor; G protein-coupled receptor; Endocrinology; Biochemistry; Medicine","score_opus":0.021370005240542476,"score_gpt":0.24835264070217583,"score_spread":0.22698263546163336,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3167896873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866895,0.0034270172,0.0059402976,0.0012272747,0.0019107201,0.00029655898,0.000052331587,0.000026690244,0.00042962312],"genre_scores_gemma":[0.98572516,0.0015823132,0.002068641,0.0007629259,0.0029803277,0.000024238494,0.00016756976,0.000091071364,0.006597762],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970023,0.0006942211,0.00059243594,0.00056294043,0.000481412,0.000666666],"domain_scores_gemma":[0.9982116,0.00018189507,0.0003944245,0.0006222314,0.00034879002,0.0002410653],"candidate_categories":["sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012840099,0.00038395997,0.00033109408,0.000052013133,0.0014065678,0.0002919644,0.0006064552,0.00024068003,0.004751772],"category_scores_gemma":[0.0002267711,0.00022532976,0.00038937168,0.00033358968,0.00018524895,0.00001448944,0.0002900565,0.0007263668,0.00018279495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046440357,0.0000661614,0.000101016696,0.000008326124,0.00017478359,0.00004246788,0.00031741237,0.0002946041,0.9817751,0.000026986763,0.012961197,0.0037675642],"study_design_scores_gemma":[0.00084432453,0.00030632335,0.000047603142,0.000068596644,0.000049522354,0.00069073035,0.000687754,0.00006313133,0.94371504,0.00014425749,0.05304205,0.00034066115],"about_ca_topic_score_codex":0.000013387012,"about_ca_topic_score_gemma":0.000038342056,"teacher_disagreement_score":0.040080853,"about_ca_system_score_codex":0.00014390779,"about_ca_system_score_gemma":0.0004311744,"threshold_uncertainty_score":0.9998935},"labels":[],"label_agreement":null},{"id":"W3168020009","doi":"10.1096/fasebj.27.1_supplement.921.3","title":"Protein Kinase G Inhibits T‐type Ca <sup>2+</sup> Channels in Rat Cerebral Arteries","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"cGMP-dependent protein kinase; Nifedipine; Protein kinase A; Vasodilation; Chemistry; Patch clamp; Cerebral arteries; Biophysics; Endocrinology; Internal medicine; Kinase; Cell biology; Electrophysiology; Biology; Biochemistry; Calcium; Mitogen-activated protein kinase kinase; Medicine","score_opus":0.010976005478802266,"score_gpt":0.2172193025403558,"score_spread":0.20624329706155353,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3168020009","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99796927,0.00037494095,0.00042202914,0.00052420894,0.00024118277,0.00028686234,0.0000030267702,0.0000060803236,0.00017238698],"genre_scores_gemma":[0.9973436,0.00004532963,0.0003275785,0.00031846183,0.00067182246,0.00002532614,0.000015975931,0.00002218972,0.0012296907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890995,0.00014653159,0.00025762062,0.00018017473,0.00015686425,0.00034886884],"domain_scores_gemma":[0.99945474,0.0000068913864,0.000117065894,0.00020331715,0.00010107861,0.00011691523],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035530087,0.00016579205,0.00014646105,0.000053088108,0.00018415759,0.00015333325,0.00023925955,0.00011403546,0.0008985347],"category_scores_gemma":[0.00006857122,0.00011118099,0.00008422937,0.000098362725,0.000055466357,0.000016742348,0.00008457875,0.0002766294,0.00009184461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054828408,0.000028962228,0.000106435196,0.000006060684,0.000017532668,0.000010434528,0.00041133544,0.0015822541,0.9951238,0.00004811733,0.0014563238,0.0011539168],"study_design_scores_gemma":[0.0005060453,0.00032146095,0.000017000792,0.000049818802,0.000006101043,0.00013411202,0.0007895397,0.0015964936,0.9934691,0.0008339842,0.0021073122,0.00016903138],"about_ca_topic_score_codex":0.000042785156,"about_ca_topic_score_gemma":0.000005200124,"teacher_disagreement_score":0.0016546989,"about_ca_system_score_codex":0.000019093615,"about_ca_system_score_gemma":0.00007812218,"threshold_uncertainty_score":0.98383254},"labels":[],"label_agreement":null},{"id":"W3168310094","doi":"10.1096/fasebj.2021.35.s1.01694","title":"Use of Novel ebBRET Biosensors for Comprehensive Signaling Profiling of One Hundred Therapeutically Relevant Human GPCRs","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Novo Nordisk Fonden; Lundbeckfonden","keywords":"G protein-coupled receptor; Receptor; Functional selectivity; Effector; Förster resonance energy transfer; Signal transduction; G protein; Computational biology; Chemistry; Biology; Rhodopsin-like receptors; Cell biology; Biochemistry; Fluorescence; Agonist","score_opus":0.10381734433129954,"score_gpt":0.3027264105016747,"score_spread":0.19890906617037518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3168310094","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9563434,0.0005086282,0.042672873,0.00011592656,0.0001229889,0.00017119946,0.00004774781,0.000004194758,0.000013028574],"genre_scores_gemma":[0.966127,0.00013036688,0.03328064,0.00014960782,0.00019430918,0.0000032971132,0.000040296272,0.00002542554,0.00004909482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988393,0.00010433288,0.00046141804,0.00017636897,0.00019913563,0.00021940382],"domain_scores_gemma":[0.9986797,0.00009835731,0.0003230612,0.00023260826,0.00060313236,0.00006317123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033754617,0.000120544064,0.00025664674,0.00003629855,0.00017542539,0.00003617237,0.00017419754,0.0001042528,0.000024451865],"category_scores_gemma":[0.00009785203,0.00009900672,0.00024165829,0.00007533479,0.00009497632,0.0000058855367,0.00006032103,0.0001603918,2.6792262e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015839581,0.00011661149,0.00004480325,0.00003444472,0.0002613905,0.000002207164,0.00010265246,0.0012802054,0.9965365,0.0008315461,0.000014152456,0.0006171004],"study_design_scores_gemma":[0.0007812921,0.00037213202,0.000059412392,0.00009372543,0.000086856206,0.00006441066,0.00047147856,0.0006175054,0.9968795,0.00027582076,0.000178549,0.000119288605],"about_ca_topic_score_codex":0.0000045117818,"about_ca_topic_score_gemma":0.000002020574,"teacher_disagreement_score":0.00978355,"about_ca_system_score_codex":0.000009345276,"about_ca_system_score_gemma":0.000114713606,"threshold_uncertainty_score":0.4037377},"labels":[],"label_agreement":null},{"id":"W3168535221","doi":"10.1096/fasebj.27.1_supplement.883.3","title":"Role of the central region of the third intracellular loop of human D1‐class dopaminergic receptors","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"King Saud University; Ontario Mental Health Foundation","keywords":"Agonist; G protein-coupled receptor; Receptor; Dopaminergic; Intracellular; Biology; Cell biology; Neuroscience; Biochemistry; Dopamine","score_opus":0.00771687654178369,"score_gpt":0.20031055202308595,"score_spread":0.19259367548130227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3168535221","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979758,0.0007211278,0.00014621245,0.00022264221,0.0003219344,0.00015442006,0.0000026646164,0.0000015354067,0.00045364126],"genre_scores_gemma":[0.99891496,0.00013279253,0.000041741216,0.00004290544,0.00020667278,0.0000022041484,0.0000022792972,0.000012859296,0.0006435806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988801,0.00021284341,0.00036798997,0.0001039025,0.00023421101,0.0002009906],"domain_scores_gemma":[0.99890196,0.000013654745,0.000502953,0.00038976845,0.00014368078,0.000047964873],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031836244,0.00011417979,0.00015988357,0.000019356617,0.00015988176,0.000015028357,0.00060829316,0.00009852503,0.00015834294],"category_scores_gemma":[0.00004190707,0.000053312633,0.00025815566,0.000094556075,0.00018926595,0.0000056923313,0.00012845125,0.00021733878,0.0000010428223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017747454,0.000035740304,0.0015737796,0.000008622376,0.000051744835,2.2248449e-7,0.00018146275,0.00027045835,0.99636865,0.00031886948,0.00058149145,0.00059121073],"study_design_scores_gemma":[0.00023937752,0.00014094087,0.001025602,0.00005463184,0.000034779754,0.000042928732,0.0006883878,0.00008734694,0.9964209,0.00077663874,0.00042334935,0.00006507703],"about_ca_topic_score_codex":0.0000673123,"about_ca_topic_score_gemma":0.0000075191865,"teacher_disagreement_score":0.00093914283,"about_ca_system_score_codex":0.000011755528,"about_ca_system_score_gemma":0.00005982706,"threshold_uncertainty_score":0.2174026},"labels":[],"label_agreement":null},{"id":"W3169037029","doi":"10.1096/fasebj.27.1_supplement.553.15","title":"Serum and glucocorticoid inducible kinase regulates hERG channels through inhibition of Nedd4–2 and activation of Rab11 recycling endosomes","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen's University","funders":"","keywords":"hERG; NEDD4; SGK1; Ubiquitin ligase; Ubiquitin; Chemistry; Endosome; Cell biology; Phosphorylation; Ion channel; Patch clamp; Potassium channel; Biology; Biochemistry; Endocrinology; Gene; Receptor; Intracellular","score_opus":0.014474133245056784,"score_gpt":0.22986514534048533,"score_spread":0.21539101209542855,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3169037029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970883,0.0006657086,0.001725522,0.00024381037,0.00008545559,0.00014184578,0.0000025930494,0.0000020546481,0.000044682554],"genre_scores_gemma":[0.99833053,0.0007084388,0.0006942118,0.000065028195,0.00012413126,0.0000033806323,0.000005988818,0.00000957523,0.00005873491],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999382,0.00006547568,0.00023015936,0.000113704366,0.00009376391,0.00011490319],"domain_scores_gemma":[0.99950844,0.00002264256,0.00023370565,0.00010859395,0.00008591202,0.000040686977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024966302,0.00008375943,0.00012793792,0.00003053889,0.00008898832,0.000029829936,0.000048920898,0.000075975026,0.00006134772],"category_scores_gemma":[0.00005481976,0.000058865713,0.000039865743,0.000051569066,0.000057523535,0.00002424733,0.00004669603,0.0000933025,4.520331e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034779066,0.0000147263045,0.00037773963,0.000023587834,0.000029832152,4.3141267e-7,0.00028050356,0.00022244931,0.9958287,0.00009683989,0.000022530303,0.0030679167],"study_design_scores_gemma":[0.00044592356,0.00021885816,0.00046193006,0.000079026955,0.000013835837,0.000051385152,0.000758593,0.0001368008,0.9949927,0.0027356674,0.000040349572,0.00006498395],"about_ca_topic_score_codex":0.000035390258,"about_ca_topic_score_gemma":8.903099e-7,"teacher_disagreement_score":0.0030029328,"about_ca_system_score_codex":0.000005224879,"about_ca_system_score_gemma":0.00002621797,"threshold_uncertainty_score":0.24004741},"labels":[],"label_agreement":null},{"id":"W3171542003","doi":"10.1096/fasebj.24.1_supplement.907.10","title":"Hyperactive mice show elevated D2High receptors, a model for schizophrenia: calcium/calmodulin‐dependent kinase II alpha knockouts","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Striatum; Endocrinology; Dopamine receptor D2; Receptor; Internal medicine; Chemistry; Calmodulin; Dopamine; Calcium; Biology; Medicine","score_opus":0.01744488398563592,"score_gpt":0.2583171460289989,"score_spread":0.24087226204336298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3171542003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9500915,0.00025345662,0.047300935,0.00046713254,0.0013230448,0.00033610966,0.0000840905,0.000017420656,0.0001263452],"genre_scores_gemma":[0.98797375,0.00009592488,0.007749433,0.00030804978,0.0015000743,0.000037325335,0.00006498349,0.00005620435,0.0022142376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984042,0.000093651885,0.0003631431,0.00037304522,0.00027903524,0.00048689602],"domain_scores_gemma":[0.9987872,0.000041164614,0.00024278655,0.00036405443,0.0003180296,0.00024676207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007441265,0.000288207,0.00024341697,0.00006006341,0.0008121064,0.000107396554,0.0005030221,0.00028311776,0.00024863565],"category_scores_gemma":[0.0001545426,0.00020416996,0.00027327193,0.00007698991,0.00007343745,0.000017781547,0.00015010548,0.0007200386,0.000009777031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071147725,0.00010401504,0.000016649807,0.000004709333,0.0001230733,0.0000049908626,0.00016671773,0.0012060374,0.99376076,0.00023723296,0.0017121941,0.001952114],"study_design_scores_gemma":[0.0015468752,0.0003478625,0.0000073692922,0.000017108063,0.00007922373,0.00023946233,0.00017401415,0.016352529,0.9771988,0.0007884001,0.002953608,0.00029478062],"about_ca_topic_score_codex":0.000014035981,"about_ca_topic_score_gemma":0.000030769996,"teacher_disagreement_score":0.0395515,"about_ca_system_score_codex":0.000029913743,"about_ca_system_score_gemma":0.0002233875,"threshold_uncertainty_score":0.832581},"labels":[],"label_agreement":null},{"id":"W3172167211","doi":"10.1096/fasebj.24.1_supplement.585.2","title":"Desensitization of the Dopamine D1‐D2 Receptor Heteromeric Complex in Primary Striatal Neurons and Bi‐functional Regulation by GRK2","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Dopamine receptor D2; Desensitization (medicine); Homologous desensitization; Agonist; G protein-coupled receptor kinase; Chemistry; Dopamine receptor D1; Enzyme-linked receptor; Beta adrenergic receptor kinase; Receptor; 5-HT5A receptor; Cell biology; Pharmacology; G protein-coupled receptor; Biology; Biochemistry","score_opus":0.010476204185370762,"score_gpt":0.2058849494603008,"score_spread":0.19540874527493005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3172167211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99673945,0.00006338379,0.0024642048,0.0002441706,0.0003397823,0.00008666754,0.00001876216,0.0000019634422,0.000041589494],"genre_scores_gemma":[0.9990628,0.00005444692,0.00035649296,0.000101794896,0.00022031268,0.0000013308517,0.000089227324,0.000009388938,0.0001042363],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993651,0.000104566425,0.00018801968,0.00010318802,0.0001375008,0.00010165104],"domain_scores_gemma":[0.9996228,0.000018477083,0.00014641538,0.0001249279,0.000053075917,0.000034261982],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002836738,0.000075917036,0.00008166911,0.000026848149,0.00013405671,0.000024782663,0.00009524883,0.000057649253,0.00009715956],"category_scores_gemma":[0.000042923537,0.000047434998,0.00004574934,0.00007778029,0.0000761008,0.0000074660825,0.00005121287,0.00018492881,7.180532e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005383157,0.000018460792,0.0015251577,0.0000027418066,0.00000980025,1.494208e-7,0.000018713476,0.00017245456,0.9957306,0.000025161533,0.00058472826,0.0018582335],"study_design_scores_gemma":[0.0005493325,0.00010017722,0.0362177,0.000010111546,0.0000111598065,0.000097182616,0.000039134473,0.0004935572,0.9609914,0.00010447214,0.0013110534,0.00007472544],"about_ca_topic_score_codex":0.0000073187334,"about_ca_topic_score_gemma":0.000008415516,"teacher_disagreement_score":0.034739174,"about_ca_system_score_codex":0.000008678461,"about_ca_system_score_gemma":0.000035914436,"threshold_uncertainty_score":0.1934343},"labels":[],"label_agreement":null},{"id":"W3172984583","doi":"10.1096/fasebj.2021.35.s1.03176","title":"β‐arrestin‐biased ACKR3 Promotes Gαi:β‐arrestin Complex Formation","year":2021,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"Arrestin; G protein-coupled receptor; Receptor; Internalization; Chemistry; Cell biology; Stimulation; Biology; Neuroscience; Biochemistry","score_opus":0.03090962685054746,"score_gpt":0.2584400477902225,"score_spread":0.22753042093967504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3172984583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9758799,0.0006195238,0.021838557,0.0005597225,0.0003569613,0.00009713972,0.000011046972,0.000011878313,0.00062528264],"genre_scores_gemma":[0.9952429,0.00011068214,0.0030291134,0.00040079464,0.0007141639,0.0000042638558,0.00010766937,0.000017588263,0.00037281858],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897426,0.0001799652,0.00025576432,0.00014744757,0.00019666181,0.00024592457],"domain_scores_gemma":[0.9993183,0.000023485165,0.00015247418,0.00022643947,0.00017645794,0.00010283808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004407617,0.00012784377,0.00011664589,0.000022544047,0.00035889292,0.00013467521,0.00021435077,0.00007598418,0.0004955107],"category_scores_gemma":[0.0001908105,0.00009056451,0.00011967447,0.00008405987,0.000040115145,0.000009370162,0.000078011864,0.00020394158,0.000028034354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027886246,0.0000267363,0.00010719565,0.0000071480486,0.000026571113,0.000020866937,0.00009700593,0.00020075955,0.9932909,0.000056838235,0.002943024,0.0031950558],"study_design_scores_gemma":[0.00044229254,0.00010537601,0.0002495396,0.000033279328,0.00002178139,0.00074112427,0.00029187297,0.0010392877,0.9899794,0.00054729014,0.006417244,0.00013151663],"about_ca_topic_score_codex":0.0000032331966,"about_ca_topic_score_gemma":0.000008254232,"teacher_disagreement_score":0.01936302,"about_ca_system_score_codex":0.000015420166,"about_ca_system_score_gemma":0.00011527352,"threshold_uncertainty_score":0.54254943},"labels":[],"label_agreement":null},{"id":"W3173170839","doi":"10.1096/fasebj.26.1_supplement.928.9","title":"Early postnatal striatal gene expression networks in rat: relevance to schizophrenia","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Striatum; Offspring; Schizophrenia (object-oriented programming); Prefrontal cortex; Neuroscience; Gene expression; Biology; Dopamine receptor D2; Downregulation and upregulation; Phenotype; Dopamine; Gene; Endocrinology; Psychology; Pregnancy; Genetics; Psychiatry; Cognition","score_opus":0.009670740279970176,"score_gpt":0.23210571821582812,"score_spread":0.22243497793585795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173170839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97934973,0.0017883391,0.017932251,0.00005922476,0.0007185462,0.00010110474,0.00000525075,0.0000042317115,0.000041294697],"genre_scores_gemma":[0.99522585,0.00017277984,0.0025373723,0.00015564948,0.0017448586,0.0000047972967,0.000013015838,0.000018615423,0.00012705605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990301,0.00010973697,0.00020820944,0.00013292492,0.00015140869,0.00036760332],"domain_scores_gemma":[0.99948555,0.000015297095,0.00008541616,0.0001992075,0.00003454747,0.00017995453],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057121343,0.000121928766,0.00010539723,0.00003743377,0.00015499318,0.00005337496,0.00025378744,0.00009791321,0.00007047401],"category_scores_gemma":[0.00005749956,0.000083653336,0.00007280503,0.00008199109,0.000017581337,0.000013830872,0.00011212923,0.00028401063,0.00001559646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003035901,0.000020956777,0.0005936648,7.8817925e-7,0.000009118866,0.0000053521217,0.00010188492,0.0011984542,0.99564576,0.000020916066,0.0004170328,0.0016824965],"study_design_scores_gemma":[0.00055257225,0.00014335998,0.0012540946,0.000030775947,0.0000058709466,0.0001322039,0.00006693885,0.00006256987,0.99682033,0.000026736683,0.0007741565,0.00013038299],"about_ca_topic_score_codex":0.000006731543,"about_ca_topic_score_gemma":0.0000023715697,"teacher_disagreement_score":0.015876098,"about_ca_system_score_codex":0.000017126771,"about_ca_system_score_gemma":0.000031258805,"threshold_uncertainty_score":0.34112838},"labels":[],"label_agreement":null},{"id":"W3173404325","doi":"10.1096/fasebj.2018.32.1_supplement.700.2","title":"Enhanced expression of Egr‐1 in vascular smooth muscle cells from spontaneously hypertensive rats: role of Giα proteins","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Vascular smooth muscle; Losartan; Gene knockdown; Antagonist; Angiotensin II; Internal medicine; Endocrinology; Angiotensin II receptor type 1; Endogeny; Receptor; Chemistry; Receptor antagonist; Spontaneously hypertensive rat; Medicine; Apoptosis; Blood pressure; Smooth muscle; Biochemistry","score_opus":0.006355293022516968,"score_gpt":0.20355085700915918,"score_spread":0.1971955639866422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173404325","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944904,0.00074332795,0.004315107,0.0000126716195,0.00013404358,0.0001500721,0.000013833782,0.0000019965737,0.00013857367],"genre_scores_gemma":[0.9976788,0.0001847915,0.0017346834,0.00005027083,0.00030062688,0.0000036589872,0.0000072955495,0.000015157701,0.000024682424],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99906904,0.00013455069,0.00029125222,0.00015337521,0.00018315105,0.00016861285],"domain_scores_gemma":[0.99927586,0.000016875321,0.00022614485,0.00025515864,0.00017352577,0.00005242393],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028878087,0.00011092227,0.00020047477,0.00003643885,0.00006929192,0.000011467291,0.0002460873,0.00010106057,0.00021595995],"category_scores_gemma":[0.000041589446,0.000074303425,0.00012089562,0.000057654037,0.000079704085,0.0000050058807,0.00006414193,0.00013463561,0.0000035301875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014183938,0.000049883132,0.00001028278,0.0000035590128,0.000023257548,0.0000071461295,0.00048402013,0.00008911261,0.9969142,0.000004756531,0.00003025695,0.002241652],"study_design_scores_gemma":[0.0004409649,0.00037596427,0.00012561446,0.000100141275,0.000016681777,0.000007103043,0.00089073804,0.00008116261,0.99710685,0.00035240845,0.000412463,0.000089909736],"about_ca_topic_score_codex":0.00009685171,"about_ca_topic_score_gemma":0.000033492568,"teacher_disagreement_score":0.003188459,"about_ca_system_score_codex":0.000010132841,"about_ca_system_score_gemma":0.000064815744,"threshold_uncertainty_score":0.3030006},"labels":[],"label_agreement":null},{"id":"W3173570391","doi":"10.1101/2021.06.21.449233","title":"Structural insights into ligand recognition and activation of the melanocortin-4 receptor","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Melanocortin 4 receptor; Heterotrimeric G protein; Agonist; Melanocortin 3 receptor; Receptor; Functional selectivity; Melanocortin; G protein-coupled receptor; Chemistry; Melanocortin receptor; Ligand (biochemistry); Biology; G protein; Cell biology; Biochemistry","score_opus":0.013040139512038347,"score_gpt":0.20741675842715632,"score_spread":0.19437661891511798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173570391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99700963,0.0012313757,0.000582645,0.000048131922,0.00071692676,0.0003583343,0.00003067546,0.000019474817,0.0000028189895],"genre_scores_gemma":[0.9966575,0.00045612064,0.0023571174,0.00008145563,0.00035222393,0.000037644273,0.0000049304826,0.000049505896,0.0000034904035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985196,0.0001288511,0.0003661495,0.00059836864,0.00020293398,0.00018409833],"domain_scores_gemma":[0.9984816,0.000013419476,0.00042291114,0.00058808835,0.00040938708,0.000084612824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001581866,0.0002889963,0.00028543925,0.000060004797,0.00013449666,0.000090124115,0.00023454918,0.0004901798,0.000027997121],"category_scores_gemma":[0.00018652924,0.00024325916,0.00012332661,0.00015565407,0.00008364535,0.000012120659,0.0004487969,0.0002983655,0.000001508532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025205476,0.000016533324,0.00096744474,0.0001539482,0.000086719665,6.222172e-7,0.000029513303,0.000018442337,0.9986293,0.000025923076,0.000028288674,0.000018064164],"study_design_scores_gemma":[0.00023366896,0.000048650894,0.007734181,0.00029074453,0.000043473065,1.3647362e-8,0.0000139825315,0.000056148274,0.9907717,0.0000111340105,0.0004977119,0.00029860568],"about_ca_topic_score_codex":0.000047255115,"about_ca_topic_score_gemma":0.0000056976896,"teacher_disagreement_score":0.007857609,"about_ca_system_score_codex":0.0000309987,"about_ca_system_score_gemma":0.00026528584,"threshold_uncertainty_score":0.9919821},"labels":[],"label_agreement":null},{"id":"W3173627605","doi":"10.1096/fasebj.22.1_supplement.1157.3","title":"Caloxin 1c2: Experimental Evidence That It Binds Plasma Membrane Calcium Pump","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McMaster University","funders":"","keywords":"Biotinylation; Streptavidin; Chemistry; Extracellular; Biotin; Membrane; Biochemistry; Biophysics; Molecular biology; Biology","score_opus":0.06359996046505509,"score_gpt":0.2857905605218916,"score_spread":0.22219060005683652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173627605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944315,0.0016016929,0.0025259997,0.00040470596,0.00051198335,0.00008961286,0.000004945114,0.000008122735,0.00042143124],"genre_scores_gemma":[0.9961663,0.0007096301,0.00029951797,0.00047704784,0.0006928798,0.000006766715,0.0000073664232,0.000023131754,0.0016173992],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882245,0.00012167617,0.00021734548,0.00020748992,0.0003095934,0.00032143324],"domain_scores_gemma":[0.9993553,0.000027441825,0.00015572095,0.0002531117,0.000051171413,0.00015725529],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038431011,0.00017314323,0.00014786804,0.000035188797,0.0004880274,0.000055859902,0.0003885184,0.00011410934,0.0006677304],"category_scores_gemma":[0.000054326574,0.00011597422,0.00016815543,0.00006000223,0.00010826968,0.0000128595975,0.000099388344,0.00025930873,0.000040622825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012010488,0.000033938595,0.00021226013,0.0000024422172,0.000042145824,0.000050962906,0.00030857348,0.00012384292,0.997126,0.000014183536,0.0017686856,0.00019689433],"study_design_scores_gemma":[0.00045072488,0.00025946402,0.000048412894,0.00003856977,0.00001442932,0.0017680704,0.0005383232,0.0001511404,0.9938019,0.000010818345,0.0027538734,0.00016430831],"about_ca_topic_score_codex":0.000018826586,"about_ca_topic_score_gemma":0.0000033500728,"teacher_disagreement_score":0.0033241003,"about_ca_system_score_codex":0.000029423687,"about_ca_system_score_gemma":0.00010719392,"threshold_uncertainty_score":0.73111796},"labels":[],"label_agreement":null},{"id":"W3173644375","doi":"10.1096/fasebj.22.1_supplement.1129.18","title":"Reduced catecholamine sensitivity is related to a decrease in adenylate cyclase activity mediated by ß1‐adrenergic receptor signaling in aged ventricular myocytes","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Forskolin; Endocrinology; Internal medicine; Agonist; Myocyte; Catecholamine; Adenylate kinase; Contraction (grammar); Cyclase; Chemistry; Receptor; Adrenergic; Biology; Medicine","score_opus":0.009889804088416094,"score_gpt":0.22752199784976335,"score_spread":0.21763219376134726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173644375","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99808186,0.0007083231,0.00029889573,0.0004242781,0.00016020506,0.00025616653,0.00003469214,0.0000149315,0.000020643425],"genre_scores_gemma":[0.9985441,0.0004243351,0.0002452152,0.0003667532,0.00010869428,0.000013406358,0.000076180855,0.000037497633,0.00018384606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976325,0.00068971567,0.00045654297,0.00040297004,0.00031119955,0.0005070675],"domain_scores_gemma":[0.9989393,0.00007882584,0.00021505136,0.00028638862,0.000085208645,0.00039526814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014104489,0.00027969154,0.00032554418,0.00018350895,0.00026680288,0.000046274734,0.00022841107,0.00025027106,0.00021475299],"category_scores_gemma":[0.00061143446,0.00022378254,0.00015576447,0.0005024255,0.000059563943,0.000019857811,0.000095577285,0.00065908977,0.000017523907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037363815,0.0001496571,0.0009005999,0.00000337984,0.000048866586,0.00051693775,0.00037930327,0.0015571867,0.9950158,0.000001011623,0.0005782132,0.00047542475],"study_design_scores_gemma":[0.0014537206,0.00017925713,0.0011868589,0.00007134108,0.000017310433,0.000573795,0.000091452755,0.00055592903,0.99535066,0.00002623382,0.00020330733,0.00029011708],"about_ca_topic_score_codex":0.00018163124,"about_ca_topic_score_gemma":0.00003688529,"teacher_disagreement_score":0.0013067531,"about_ca_system_score_codex":0.000116211966,"about_ca_system_score_gemma":0.00020730791,"threshold_uncertainty_score":0.91255873},"labels":[],"label_agreement":null},{"id":"W3173926394","doi":"10.1096/fasebj.27.1_supplement.1031.20","title":"Determinants of physical and functional coupling between Thromboxane A2 receptor and Gαq","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Manitoba Health Research Council","keywords":"G protein-coupled receptor; Heterotrimeric G protein; G protein; Receptor; Chemistry; Cysteine; Thromboxane receptor; Thromboxane A2; Biochemistry; Cell biology; Biology","score_opus":0.01613908844696178,"score_gpt":0.24385712289083294,"score_spread":0.22771803444387118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3173926394","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987148,0.00033286953,0.00072910346,0.00004656506,0.00007950709,0.00006373138,0.0000056346025,0.0000018393785,0.000025944079],"genre_scores_gemma":[0.9989151,0.0001327133,0.00026683437,0.000026903079,0.0005644972,0.000002169553,0.0000049914497,0.00000903754,0.00007780332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995011,0.000024529838,0.00013958884,0.000105386054,0.000104896506,0.00012451851],"domain_scores_gemma":[0.99966174,0.000028434031,0.00009748777,0.000079335,0.00005958797,0.000073436786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020035332,0.000082666775,0.00012931775,0.000016112672,0.00013978244,0.000035907386,0.00006436366,0.00005030226,0.000100370664],"category_scores_gemma":[0.000022381817,0.000052924974,0.00004387667,0.000021937001,0.000082654544,0.000007104263,0.000056591303,0.0001108454,0.0000036580468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011595242,0.000009651587,0.010355938,0.0000055281917,0.00002702695,2.6651864e-7,0.000063611384,0.000017516772,0.9861835,0.00001555974,0.00011705943,0.0031927421],"study_design_scores_gemma":[0.00030251397,0.00026342485,0.014325048,0.00002404385,0.000025921077,0.000052212115,0.00017841379,0.0005710721,0.98360014,0.0004369184,0.00013521138,0.000085091444],"about_ca_topic_score_codex":0.000008536917,"about_ca_topic_score_gemma":8.033674e-7,"teacher_disagreement_score":0.00396911,"about_ca_system_score_codex":0.0000033159379,"about_ca_system_score_gemma":0.000021039234,"threshold_uncertainty_score":0.21582179},"labels":[],"label_agreement":null},{"id":"W3174053852","doi":"10.1096/fasebj.2018.32.1_supplement.533.45","title":"Muscarinic Antagonist Mediated Activation of ERK Signaling Depends on β‐arrestin Recruitment to Augment Axonal Outgrowth in Neurons","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"CREB; MAPK/ERK pathway; Cell biology; Neurite; Muscarinic acetylcholine receptor; Signal transduction; Phosphorylation; Pirenzepine; Muscarinic acetylcholine receptor M1; Chemistry; Biology; Molecular biology; Receptor; Biochemistry; Transcription factor","score_opus":0.041134645359020755,"score_gpt":0.2893549383927806,"score_spread":0.24822029303375984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174053852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953283,0.000028009585,0.0034756802,0.00033641298,0.00032291666,0.00021451904,0.000008776023,0.0000039862884,0.00028141122],"genre_scores_gemma":[0.9984073,0.000024828649,0.00061056437,0.000394729,0.00046221763,0.000013507589,0.00002067702,0.000016367349,0.000049783717],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988485,0.00015622417,0.00032307554,0.00018797579,0.0002534142,0.00023080542],"domain_scores_gemma":[0.99942964,0.000041980395,0.00016618846,0.00017766599,0.000082622566,0.00010189156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005701873,0.00013013776,0.0001333937,0.00008851152,0.00015373006,0.000031866988,0.00022849752,0.000069006004,0.00014027902],"category_scores_gemma":[0.00011209036,0.00009413605,0.00007450446,0.00012849305,0.00004333467,0.0000044072817,0.00006749169,0.00019156416,0.000010552562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003019496,0.000064660664,0.00053490227,0.0000026660819,0.000027702437,0.0000037911148,0.00015897895,0.00075559574,0.9954972,0.000051588406,0.00014418706,0.002456751],"study_design_scores_gemma":[0.0005324873,0.0010537991,0.0016818147,0.00006558208,0.000010886189,0.000020408834,0.00014732896,0.00015740997,0.995372,0.000101635495,0.0007511278,0.000105534426],"about_ca_topic_score_codex":0.00002251347,"about_ca_topic_score_gemma":0.000021888096,"teacher_disagreement_score":0.0030790367,"about_ca_system_score_codex":0.000043542226,"about_ca_system_score_gemma":0.00010202571,"threshold_uncertainty_score":0.38387567},"labels":[],"label_agreement":null},{"id":"W3174197955","doi":"10.1096/fasebj.2019.33.1_supplement.503.17","title":"Trans‐synaptic regulation of group III mGluR pharmacology by endogenous allosteric modulators implicated in neuropsychiatric disease","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institutes of Health","keywords":"Allosteric regulation; Endogeny; Neuroscience; Pharmacology; Metabotropic glutamate receptor; Chemistry; Medicine; Glutamate receptor; Biology; Internal medicine; Receptor","score_opus":0.008651668048180695,"score_gpt":0.2190646009375055,"score_spread":0.2104129328893248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174197955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963152,0.0013183432,0.0015179616,0.00014264541,0.00038649037,0.00024730805,0.000012380469,0.000004516297,0.00005517323],"genre_scores_gemma":[0.9991713,0.0003315931,0.00007131534,0.00015737933,0.00013296853,0.0000057410043,0.000035780387,0.00002083151,0.00007306318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896663,0.0001741431,0.00031516352,0.00018793473,0.00012934468,0.00022680848],"domain_scores_gemma":[0.9994943,0.00001293133,0.00017683662,0.00017678714,0.00003855362,0.00010055776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026893668,0.00012703757,0.00015432344,0.00006634469,0.00006474139,0.000014006602,0.00023795122,0.0000684882,0.0002477054],"category_scores_gemma":[0.0000053171116,0.000095383126,0.000113143185,0.0001403001,0.000031202595,0.000006602623,0.00003085403,0.00017440635,0.0000038120938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035443247,0.00007803908,0.0011020435,0.000010938773,0.00005289525,0.0000034157067,0.000054132415,0.0012982346,0.996033,0.000018159852,0.00014125528,0.00085341657],"study_design_scores_gemma":[0.002750675,0.00070142164,0.0046960698,0.000016653492,0.00010576103,0.00018093991,0.00008471241,0.0030780365,0.9869665,0.00033103515,0.0008481045,0.00024009627],"about_ca_topic_score_codex":0.000013134588,"about_ca_topic_score_gemma":0.0000013716875,"teacher_disagreement_score":0.009066543,"about_ca_system_score_codex":0.00001568552,"about_ca_system_score_gemma":0.000048654383,"threshold_uncertainty_score":0.3889611},"labels":[],"label_agreement":null},{"id":"W3174330709","doi":"10.1096/fasebj.2019.33.1_supplement.502.5","title":"Identification and Characterization of UBE2O as a New β‐arrestin Interactor","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Arrestin; Cell biology; Ubiquitin ligase; Interactome; Ubiquitin; Biotinylation; Biology; Proximity ligation assay; Protein–protein interaction; Scaffold protein; G protein-coupled receptor; Signal transduction; Immunoprecipitation; Molecular biology; Biochemistry; Receptor; Gene","score_opus":0.00750767863874916,"score_gpt":0.23114874941925503,"score_spread":0.22364107078050588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174330709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954052,0.00007795934,0.003957287,0.00017624546,0.00025921487,0.000063841326,0.0000023098157,0.000001474569,0.000056465542],"genre_scores_gemma":[0.9980806,0.00011077039,0.000067083514,0.00008495246,0.00020174879,5.465351e-7,0.00001560265,0.000006219461,0.0014324583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996211,0.000035785903,0.0001398687,0.00007156604,0.000070373506,0.000061327846],"domain_scores_gemma":[0.999663,0.0000056065783,0.00014398877,0.00009603937,0.00004248183,0.000048901435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018148153,0.000046829777,0.000055206696,0.000018602124,0.000037382746,0.000036354886,0.0000845939,0.00003336674,0.00019655532],"category_scores_gemma":[0.000038394024,0.00003240503,0.000029966566,0.000025429803,0.000012398227,0.000005942182,0.000024904213,0.000061208324,0.000012851338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036828565,0.0000058255714,0.00060624775,0.000003411175,0.000013094422,1.7948379e-7,0.00010894812,0.0000047553117,0.99626976,0.00007093157,0.00005862041,0.0028214208],"study_design_scores_gemma":[0.00017658496,0.0000962849,0.0015492237,0.00001983724,0.000008060382,0.00004576477,0.000065600565,0.0000753023,0.99675256,0.00017150707,0.0009990633,0.0000402087],"about_ca_topic_score_codex":0.000004700139,"about_ca_topic_score_gemma":5.1343784e-7,"teacher_disagreement_score":0.0038902035,"about_ca_system_score_codex":0.0000034007428,"about_ca_system_score_gemma":0.00004759741,"threshold_uncertainty_score":0.2152143},"labels":[],"label_agreement":null},{"id":"W3174375181","doi":"10.1096/fasebj.27.1_supplement.1040.1","title":"Role of the GRK2 extreme amino terminus and active site tether in forming G protein‐coupled receptor docking site","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"G protein-coupled receptor kinase; G protein-coupled receptor; Beta adrenergic receptor kinase; Phosphorylation; Receptor; Protein kinase domain; Agonist; Docking (animal); Kinase; Cell biology; Biochemistry; Biology; Chemistry; Mutant","score_opus":0.009112591334305932,"score_gpt":0.20591666881641335,"score_spread":0.19680407748210743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174375181","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99864656,0.0004651904,0.00022960916,0.00010294851,0.000073503186,0.00031105042,0.0000046708437,0.0000024216142,0.00016402776],"genre_scores_gemma":[0.9989634,0.000050320694,0.00038220626,0.000065793734,0.00018694645,0.000016886497,0.0000027901194,0.00001690437,0.00031473892],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991473,0.000109117565,0.00023184923,0.0001419051,0.0001461609,0.00022365405],"domain_scores_gemma":[0.99946076,0.00001696511,0.0002129754,0.0001869771,0.000070114635,0.000052220974],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033383226,0.00012623164,0.00013260324,0.00003495969,0.00016791007,0.0000517082,0.00019658497,0.000085512846,0.00017623705],"category_scores_gemma":[0.00004912497,0.00007086089,0.000085602,0.00006824701,0.00006100278,0.000016651571,0.000120812256,0.00023204977,0.000004754544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000040101004,0.000015470527,0.0014622618,0.0000049826995,0.000022619879,8.6004286e-7,0.00073378155,0.000050297323,0.9883125,0.000009458707,0.00001544866,0.009332227],"study_design_scores_gemma":[0.00039581012,0.0000908354,0.0017264234,0.00008415675,0.0000116403235,0.00006377085,0.0008078448,0.0009237456,0.9950119,0.00043637605,0.00034238855,0.00010509764],"about_ca_topic_score_codex":0.00009680795,"about_ca_topic_score_gemma":0.000039628914,"teacher_disagreement_score":0.009227129,"about_ca_system_score_codex":0.000017632605,"about_ca_system_score_gemma":0.0000372915,"threshold_uncertainty_score":0.28896233},"labels":[],"label_agreement":null},{"id":"W3174713348","doi":"10.1096/fasebj.2019.33.1_supplement.679.9","title":"Overexpression of Egr‐1 contributes to the enhanced expression of Giα proteins and hyperproliferation of vascular smooth muscle cells from spontaneously hypertensive rats","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Vascular smooth muscle; Losartan; Angiotensin II; Endocrinology; Internal medicine; MAPK/ERK pathway; Antagonist; Receptor; Chemistry; Downregulation and upregulation; Receptor antagonist; Angiotensin II receptor type 1; Growth factor; Platelet-derived growth factor receptor; Signal transduction; Biology; Medicine; Biochemistry; Gene; Smooth muscle","score_opus":0.005322958887709214,"score_gpt":0.19807095794203378,"score_spread":0.19274799905432455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174713348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915261,0.0007861725,0.0070833624,0.00005619248,0.000115100265,0.00037837547,0.00003067055,0.0000012877753,0.000022731643],"genre_scores_gemma":[0.9988148,0.00017910033,0.0007783269,0.00008209704,0.00009088392,0.000004707739,0.000009958701,0.000010312101,0.000029794508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914837,0.00014397074,0.0002725714,0.00013553211,0.00018890358,0.000110679284],"domain_scores_gemma":[0.9991952,0.00004451593,0.0002612352,0.00024961718,0.00020881364,0.000040587467],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031446773,0.00009952451,0.00021417279,0.000024580975,0.000075506876,0.000014360918,0.00017335752,0.000081359605,0.000055719687],"category_scores_gemma":[0.00006004238,0.000053548047,0.00009094577,0.000040704323,0.00003694402,0.0000062302474,0.000075981305,0.00009859179,0.0000010834087],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026083653,0.000028512895,0.000039017938,0.000011116358,0.00003429151,6.771518e-7,0.0002912769,0.00066110183,0.997718,0.00001023245,0.00006095721,0.000884005],"study_design_scores_gemma":[0.0005066373,0.00033286505,0.0003619217,0.00021504612,0.000026630312,0.0000045663714,0.00042949556,0.00012868701,0.9975884,0.00013092329,0.00021105699,0.000063761094],"about_ca_topic_score_codex":0.00003506265,"about_ca_topic_score_gemma":0.0000041734484,"teacher_disagreement_score":0.007288712,"about_ca_system_score_codex":0.0000056783074,"about_ca_system_score_gemma":0.000045922665,"threshold_uncertainty_score":0.21836258},"labels":[],"label_agreement":null},{"id":"W3174722040","doi":"10.1096/fasebj.23.1_supplement.945.9","title":"Mechanisms regulating the dopamine D1‐D2 receptor heteromeric signaling complex","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"","keywords":"Agonist; Signal transduction; Dopamine receptor D1; Cell biology; Dopamine receptor D2; Chemistry; Desensitization (medicine); Homologous desensitization; Receptor; G protein; G protein-coupled receptor; Pharmacology; Biology; Biochemistry","score_opus":0.018951354518557777,"score_gpt":0.24512277561231283,"score_spread":0.22617142109375504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174722040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94402415,0.0005620853,0.053046662,0.0013623263,0.00042223957,0.00017194949,0.0000060864504,0.000018387034,0.00038613813],"genre_scores_gemma":[0.99160963,0.00010052896,0.0056730327,0.0012431523,0.00089765165,0.0000035821968,0.000025388457,0.000024989999,0.00042202312],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99847543,0.00023587012,0.000366096,0.0002230122,0.00030485186,0.00039476287],"domain_scores_gemma":[0.99914056,0.000034141758,0.00026758318,0.00034763943,0.000098701326,0.00011134605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010252899,0.00021157142,0.00018244887,0.00003614279,0.0008119148,0.00016924553,0.00053856877,0.00008913424,0.00049864437],"category_scores_gemma":[0.00006136614,0.00011831179,0.00020690518,0.00012948045,0.00005995196,0.000008522957,0.000071238945,0.00032902858,0.000020196649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053254138,0.00002058309,0.0000063044645,0.0000017024844,0.000043120777,0.0000029586574,0.00009412212,0.00083607004,0.9889709,0.00039967702,0.00069451577,0.008876787],"study_design_scores_gemma":[0.00042866144,0.0005089289,0.00012690581,0.00003110475,0.000031401625,0.0003456594,0.00047724118,0.0007057867,0.9913215,0.0025158739,0.0032999525,0.00020696475],"about_ca_topic_score_codex":0.000003842328,"about_ca_topic_score_gemma":0.0000011536815,"teacher_disagreement_score":0.047585525,"about_ca_system_score_codex":0.000023000819,"about_ca_system_score_gemma":0.000041045547,"threshold_uncertainty_score":0.62446743},"labels":[],"label_agreement":null},{"id":"W3174773013","doi":"10.1096/fasebj.29.1_supplement.lb471","title":"The Discovery of Novel TAAR1 Ligands through the use of a Homology Model and <i>in silico</i> Screening","year":2015,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"In silico; Chemistry; Potency; Pharmacology; Agonist; Homology modeling; Computational biology; Stereochemistry; Receptor; Biochemistry; In vitro; Biology; Enzyme","score_opus":0.06295751263812276,"score_gpt":0.26708647822533915,"score_spread":0.20412896558721638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174773013","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9411776,0.001369649,0.056855917,0.00040007677,0.00007433456,0.00006878796,0.000011200701,8.556142e-7,0.000041578514],"genre_scores_gemma":[0.9975228,0.0005131141,0.001516099,0.00017488119,0.00009082851,0.0000022507147,0.0000021278918,0.0000093545505,0.00016859378],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930435,0.00006705711,0.00024486298,0.000092055234,0.00013361184,0.00015807577],"domain_scores_gemma":[0.9994333,0.00007158087,0.00018154476,0.0002083911,0.00007402262,0.00003116276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064442353,0.000085687956,0.00012475897,0.00001306811,0.00012970903,0.000047004432,0.00023332772,0.00006155572,8.956414e-7],"category_scores_gemma":[0.00010334148,0.000039126535,0.00007109183,0.000053170563,0.0001880292,0.000014486026,0.0001179004,0.00016599888,7.48185e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001963388,0.000024607978,0.00022541397,0.0000022064671,0.0000388098,9.101693e-7,0.00043396011,0.027240004,0.97068304,0.0005231937,0.00022299908,0.00040851595],"study_design_scores_gemma":[0.0009667267,0.00024644137,0.00008232177,0.00003655485,0.000032538283,0.00020141563,0.0011808552,0.01717626,0.97788584,0.0014531749,0.0006453631,0.0000924966],"about_ca_topic_score_codex":0.000044020337,"about_ca_topic_score_gemma":0.00003222838,"teacher_disagreement_score":0.05634515,"about_ca_system_score_codex":0.000004515324,"about_ca_system_score_gemma":0.00007910771,"threshold_uncertainty_score":0.15955338},"labels":[],"label_agreement":null},{"id":"W3175151254","doi":"10.1096/fasebj.20.4.a248-b","title":"Caveolin‐1 knockout alters β‐adrenoceptor (β‐AR) function in mouse small intestine","year":2006,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Caveolae; Endocrinology; Knockout mouse; Internal medicine; Agonist; Receptor; Caveolin 1; Isoprenaline; Chemistry; Small intestine; Carbachol; Caveolin 3; Biology; Cell biology; Signal transduction; Medicine","score_opus":0.010847707238205549,"score_gpt":0.2098304153960027,"score_spread":0.19898270815779714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175151254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98227286,0.000515223,0.01618499,0.00013364764,0.00037199343,0.000086874556,0.0000057648253,0.000008999727,0.0004196184],"genre_scores_gemma":[0.99577427,0.00006258441,0.00069249334,0.00022743059,0.0010747773,0.0000050218437,0.000035161782,0.0000227815,0.0021054558],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907583,0.0000942898,0.00027655467,0.00016748547,0.00011781094,0.00026804826],"domain_scores_gemma":[0.99956125,0.000013882332,0.00012466387,0.00016922009,0.000065734566,0.00006525637],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043249995,0.00014070158,0.000115880226,0.000059637838,0.00014247862,0.00005945342,0.00019884105,0.00008749273,0.00022013584],"category_scores_gemma":[0.00003733937,0.000099558085,0.00009961494,0.00007509372,0.000038180075,0.000004650191,0.00004997675,0.0002531192,0.000018321427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010192471,0.000037576003,0.0011144051,0.000002740398,0.000016847831,0.00000659981,0.000029955474,0.0020365801,0.99428344,0.000074946154,0.0008452227,0.0014497477],"study_design_scores_gemma":[0.00064607203,0.0002449937,0.00056604855,0.00001772989,0.000015829393,0.00015081672,0.00013510647,0.00030795563,0.9949627,0.0005089131,0.0022962622,0.00014757465],"about_ca_topic_score_codex":0.000096433905,"about_ca_topic_score_gemma":0.00011069201,"teacher_disagreement_score":0.015492495,"about_ca_system_score_codex":0.000030095778,"about_ca_system_score_gemma":0.000054931734,"threshold_uncertainty_score":0.4059861},"labels":[],"label_agreement":null},{"id":"W3175591306","doi":"10.1096/fasebj.2018.32.1_supplement.805.21","title":"Muscarinic Acetylcholine Type 1 Receptor Constrains Neurite Outgrowth by Inhibiting Microtubule Polymerization and Mitochondrial Trafficking in Adult Sensory Neurons: A Phenotype Rescued by Antagonist Treatment","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital; University of Manitoba","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Neurite; Cell biology; Muscarinic acetylcholine receptor; Biology; Cytoskeleton; Receptor; Neuroscience; Chemistry; Biochemistry; Cell; In vitro","score_opus":0.010497439988409303,"score_gpt":0.23838359067657475,"score_spread":0.22788615068816545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175591306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973275,0.0009304034,0.00061670033,0.00026586783,0.00047959792,0.00020948744,0.000077242505,0.000010878598,0.000082320556],"genre_scores_gemma":[0.9966851,0.0011052084,0.00050906575,0.00038000135,0.000935248,0.000004509776,0.00013282867,0.000033882643,0.0002141465],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987407,0.00020843232,0.000332218,0.00028928713,0.00012160745,0.00030777763],"domain_scores_gemma":[0.99948496,0.000022663131,0.00017131153,0.00013741311,0.00009180156,0.000091833725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017334083,0.00020077318,0.00017698634,0.000049436858,0.00032330165,0.00011699945,0.00012229438,0.000121215475,0.000042261512],"category_scores_gemma":[0.00008044016,0.00015435841,0.0000640838,0.00011072041,0.0001597015,0.000011822409,0.00004348852,0.00019921607,0.0000036171696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029922143,0.00005809382,0.0001323127,0.0000037286702,0.00003276549,0.0000031563993,0.00040479875,0.0000063562757,0.9942353,0.00000824878,0.00094818603,0.0038678364],"study_design_scores_gemma":[0.0017141887,0.00078310753,0.000014103345,0.000039742812,0.000026972408,0.000111451074,0.00051586,0.00024444348,0.9941769,0.00000514723,0.0021906253,0.00017743297],"about_ca_topic_score_codex":0.00005840903,"about_ca_topic_score_gemma":0.000037205624,"teacher_disagreement_score":0.0036904034,"about_ca_system_score_codex":0.000030870426,"about_ca_system_score_gemma":0.00009386276,"threshold_uncertainty_score":0.6294553},"labels":[],"label_agreement":null},{"id":"W3175607308","doi":"10.1096/fasebj.26.1_supplement.lb456","title":"Triacsin C Suppresses Non‐Esterified Fatty Acids (NEFA) and Increases Nitric Oxide (NO) Synthesis","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"NEFA; Enos; Hyperlipidemia; Internal medicine; Chemistry; Endocrinology; Nitric oxide; Fatty acid; Nitric oxide synthase; Biochemistry; Medicine","score_opus":0.013717517115212548,"score_gpt":0.23324715446938085,"score_spread":0.2195296373541683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175607308","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99281496,0.0018675701,0.004699809,0.000040259583,0.00018387524,0.00009006653,0.000013929508,0.0000067346036,0.0002828175],"genre_scores_gemma":[0.99677384,0.0007845897,0.0011544055,0.00016079869,0.00080270437,0.000010259727,0.000006432511,0.000022592923,0.00028440251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989527,0.00019374769,0.00022103539,0.00013890024,0.00015492563,0.00033868637],"domain_scores_gemma":[0.9993065,0.00008237137,0.00013323041,0.00021055808,0.000072858704,0.00019446446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007288173,0.00016521158,0.00017714428,0.000045895067,0.00028431727,0.0001055024,0.00021495543,0.00010991954,0.00027613397],"category_scores_gemma":[0.000250343,0.00010732861,0.00010654553,0.000058765123,0.00006323297,0.000016798604,0.000078177225,0.00017018487,0.000019021098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016369924,0.000048528196,0.00339112,0.000008526275,0.000069374546,0.000003127634,0.000031568914,0.000008741353,0.993762,0.000008181954,0.00044377946,0.0020613077],"study_design_scores_gemma":[0.00037462573,0.00008106302,0.004926658,0.000027778624,0.00007681212,0.00036013228,0.00019091152,0.000029069131,0.9916998,0.000040155188,0.0020294187,0.0001635412],"about_ca_topic_score_codex":0.00002029982,"about_ca_topic_score_gemma":8.803028e-7,"teacher_disagreement_score":0.003958876,"about_ca_system_score_codex":0.000010282186,"about_ca_system_score_gemma":0.00004492969,"threshold_uncertainty_score":0.43767336},"labels":[],"label_agreement":null},{"id":"W3175623478","doi":"10.1096/fasebj.22.1_supplement.1044.5","title":"RGS2 gene product from candidate hypertension allele shows decreased plasma membrane association and inhibition of Gq","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"RGS2; Missense mutation; Regulator of G protein signaling; Mutant; Allele; G protein; Biology; Cell biology; Gene; Mutation; Chemistry; Signal transduction; Genetics; GTPase-activating protein","score_opus":0.012346191962216688,"score_gpt":0.1991284694905103,"score_spread":0.18678227752829363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175623478","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984745,0.00060502236,0.00050468754,0.00015621829,0.00011340302,0.000079431455,0.000027346572,0.0000035149615,0.000035906913],"genre_scores_gemma":[0.9973728,0.0011326162,0.0007419265,0.00010694146,0.00037967175,0.0000017995512,0.00010297149,0.000011089822,0.0001501614],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992578,0.00010105847,0.00019210285,0.00013799829,0.00017811537,0.00013290047],"domain_scores_gemma":[0.99948967,0.000017999231,0.00019523098,0.00011767011,0.00011337612,0.00006605127],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033301915,0.00008987787,0.00012871253,0.000023449848,0.00019835714,0.00001644853,0.00006234362,0.00007265617,0.00007797362],"category_scores_gemma":[0.0000796782,0.00006286294,0.000057355053,0.00003411698,0.000027732354,0.0000066984485,0.00003026545,0.00011038414,0.0000017433869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011304867,0.000025261364,0.0010803697,0.000002190157,0.00005905788,0.00000909273,0.00008477325,0.000078960606,0.99755573,0.0000024469023,0.0005749915,0.00041404687],"study_design_scores_gemma":[0.00070311106,0.00010415086,0.00070669415,0.000012462715,0.000035851746,0.0001896033,0.000049090504,0.00033249313,0.9974159,0.00007895887,0.00029157457,0.00008013346],"about_ca_topic_score_codex":0.000081060796,"about_ca_topic_score_gemma":0.00002139944,"teacher_disagreement_score":0.001101647,"about_ca_system_score_codex":0.000018271423,"about_ca_system_score_gemma":0.000058365866,"threshold_uncertainty_score":0.25634763},"labels":[],"label_agreement":null},{"id":"W3175825531","doi":"10.1096/fasebj.2018.32.1_supplement.lb661","title":"Use of BRET‐based biosensors to characterize the adhesion GPCR ADGRE5/CD97 signalling profile","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Q & T Research; Université de Sherbrooke; Université de Montréal","funders":"Mitacs","keywords":"G protein-coupled receptor; Receptor; Cell biology; Integrin; Chemistry; Gene isoform; Cell adhesion; Biology; Biochemistry; Gene; Cell","score_opus":0.037953903612985326,"score_gpt":0.2510251322455647,"score_spread":0.21307122863257938,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175825531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903108,0.0000764987,0.008503923,0.00049452734,0.00032548176,0.000191408,0.000025737503,0.00000591851,0.00006569922],"genre_scores_gemma":[0.99604416,0.000037451053,0.001769378,0.0008140582,0.0008982969,0.000005127001,0.0000146833845,0.000023126202,0.0003937016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888813,0.00018008334,0.00028277113,0.00016908458,0.00022507651,0.00025484903],"domain_scores_gemma":[0.9990711,0.000044073626,0.00021457321,0.00029664417,0.00026857437,0.00010501043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006608147,0.0001416412,0.00013734879,0.000041969193,0.00032972253,0.00008058293,0.00034438804,0.000087091736,0.0002860496],"category_scores_gemma":[0.00013470295,0.00007651129,0.00012944524,0.00012544298,0.0000987345,0.0000075431467,0.0000755339,0.00016859705,0.00002650485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018134799,0.000022083337,0.00007713125,0.000003936322,0.000033673357,0.0000020708248,0.00013918482,0.00007972821,0.9968317,0.000024582829,0.00085230987,0.0017522582],"study_design_scores_gemma":[0.00019697656,0.0005079468,0.00025336066,0.000056948782,0.000024542482,0.000037717648,0.00010684137,0.0005941467,0.9918783,0.00003169214,0.006197993,0.000113547794],"about_ca_topic_score_codex":0.000013050856,"about_ca_topic_score_gemma":0.0000043056484,"teacher_disagreement_score":0.0067345453,"about_ca_system_score_codex":0.0000107743235,"about_ca_system_score_gemma":0.000091016926,"threshold_uncertainty_score":0.31320423},"labels":[],"label_agreement":null},{"id":"W3175919488","doi":"10.1096/fasebj.22.1_supplement.1050.3","title":"Opposite Regulation of Human D1‐like Dopaminergic Responsiveness by Protein Kinase C is Shaped by Two Critical Serine Residues of the Third Intracellular Loop of Human D5 Dopaminergic Receptor","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Serine; Biology; Activator (genetics); Receptor; Dopaminergic; Molecular biology; Phosphorylation; Biochemistry; Dopamine; Endocrinology","score_opus":0.01364419642615088,"score_gpt":0.2551610731656133,"score_spread":0.24151687673946243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3175919488","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970666,0.0015345967,0.0006101755,0.00028498168,0.00010433389,0.0002562234,0.00007004966,0.000005138432,0.00006786572],"genre_scores_gemma":[0.9972824,0.00011727897,0.00022377254,0.000059074824,0.00017275907,0.000008931439,0.00006244529,0.00003183735,0.0020414917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99782974,0.0004968068,0.00071420637,0.00025249764,0.00044203995,0.00026468482],"domain_scores_gemma":[0.99850076,0.000037863996,0.00053086434,0.00043971103,0.0003929422,0.00009785818],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007793876,0.00022513498,0.0003445674,0.000062174884,0.00038250236,0.000019623329,0.00048666983,0.00014846286,0.00024171166],"category_scores_gemma":[0.000090274465,0.00014931045,0.00022401317,0.00016882598,0.00042381877,0.000016363556,0.00013976659,0.00027137744,9.613711e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003401376,0.00013598934,0.000262057,0.000048767626,0.00006537082,0.000004374453,0.00014644761,0.000053254753,0.99696404,0.00024583822,0.0016758905,0.00005781619],"study_design_scores_gemma":[0.0008449261,0.0007764949,0.0001998607,0.00015270717,0.000052531454,0.00007279849,0.00014782463,0.000079256286,0.996986,0.0002586321,0.00025987058,0.00016914819],"about_ca_topic_score_codex":0.00007039783,"about_ca_topic_score_gemma":0.0000070605197,"teacher_disagreement_score":0.001973626,"about_ca_system_score_codex":0.0000217266,"about_ca_system_score_gemma":0.00008582996,"threshold_uncertainty_score":0.6088703},"labels":[],"label_agreement":null},{"id":"W3176116382","doi":"10.1096/fasebj.22.1_supplement.723.1","title":"[beta]1 adrenergic receptor ([beta]1AR)‐epidermal growth factor receptor (EGFR) interaction regulates ERK cellular activity","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Cell biology; MAPK/ERK pathway; Transactivation; Arrestin; HEK 293 cells; Epidermal growth factor receptor; Signal transduction; G protein-coupled receptor; Epidermal growth factor; Phosphorylation; Cardioprotection; Receptor; Chemistry; Stimulation; Biology; Internal medicine; Endocrinology; Biochemistry; Transcription factor; Medicine","score_opus":0.019073154749049727,"score_gpt":0.23180718311053222,"score_spread":0.2127340283614825,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176116382","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925795,0.0008438783,0.0037907995,0.00049288437,0.0016944723,0.0001804342,0.000032229033,0.000032237705,0.00035357123],"genre_scores_gemma":[0.99367857,0.0012274309,0.00092229166,0.00020556078,0.0021688337,0.000011249101,0.00007576281,0.000062814295,0.0016474805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99769926,0.0004374063,0.0004614277,0.00043405982,0.00040935617,0.0005584789],"domain_scores_gemma":[0.99859154,0.000055397104,0.00043201738,0.00042214274,0.00022756479,0.00027134278],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005183962,0.0003797039,0.0003433259,0.000097456534,0.00083067914,0.00010985293,0.00049774727,0.00023464333,0.0016338271],"category_scores_gemma":[0.000081011174,0.00027478798,0.00041649883,0.000155535,0.00014815397,0.000046562127,0.0001383303,0.00064181717,0.00010975283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029225962,0.00009181459,0.00045595528,0.000009291878,0.0001613126,0.00001553546,0.000180817,0.00016731952,0.99245524,0.000051257353,0.004442419,0.0016767497],"study_design_scores_gemma":[0.0006262159,0.00035241887,0.00041883977,0.00003791937,0.000038042188,0.00045698613,0.00015125173,0.00011529373,0.9884262,0.000064204665,0.008952859,0.0003597626],"about_ca_topic_score_codex":0.00004107222,"about_ca_topic_score_gemma":0.0000053662156,"teacher_disagreement_score":0.0045104404,"about_ca_system_score_codex":0.000087732114,"about_ca_system_score_gemma":0.0001501082,"threshold_uncertainty_score":0.99997044},"labels":[],"label_agreement":null},{"id":"W3176316320","doi":"10.1096/fasebj.2018.32.1_supplement.568.13","title":"Changes in the participation and expression of angiotensin II receptor At1 in heart and kidney of rats 6 weeks old with neonatal administration of de dexametasone and hyperbaric oxygen therapy","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Comisión de Operación y Fomento de Actividades Académicas, Instituto Politécnico Nacional; Instituto Politécnico Nacional; Swine Innovation Porc","keywords":"Angiotensin II receptor type 1; Medicine; Hyperbaric oxygen; Angiotensin II; Kidney; Renin–angiotensin system; Receptor; Receptor expression; Internal medicine; Endocrinology; Renal function; Anesthesia; Blood pressure","score_opus":0.015815916945397274,"score_gpt":0.25226007055084265,"score_spread":0.23644415360544538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176316320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983322,0.0009055888,0.00020086202,0.0004431748,0.000014597811,0.0000948582,0.00000510638,4.4137872e-7,0.0000031400368],"genre_scores_gemma":[0.9978945,0.0006576035,0.0012793146,0.000098656834,0.000053186413,0.0000024712942,0.00000440278,0.0000043293458,0.0000055153027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994966,0.00013103778,0.00013531218,0.00007662468,0.000080063255,0.00008035323],"domain_scores_gemma":[0.99971724,0.000018748966,0.000112172784,0.00007316548,0.000045827906,0.000032836353],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053621695,0.00005767407,0.000101962774,0.000030699593,0.000050735816,0.000008633384,0.00004457144,0.00004741262,0.000009050997],"category_scores_gemma":[0.000029121775,0.00003189102,0.000012070118,0.000052850985,0.00010170852,0.000006388673,0.000019361714,0.00005847959,1.5123051e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042335922,0.000026912077,0.0050645466,0.000006211301,0.0000088173965,4.329577e-7,0.0013544388,0.000003180524,0.9913546,0.000008980248,0.000030014024,0.0017185321],"study_design_scores_gemma":[0.00052671065,0.0013662857,0.014658812,0.00006722232,0.000008321562,0.00005677192,0.00044516393,0.00008214995,0.98262054,0.000042940614,0.00008737718,0.00003772127],"about_ca_topic_score_codex":0.000024139921,"about_ca_topic_score_gemma":0.000053744556,"teacher_disagreement_score":0.009594265,"about_ca_system_score_codex":0.0000025069041,"about_ca_system_score_gemma":0.000036360936,"threshold_uncertainty_score":0.13004781},"labels":[],"label_agreement":null},{"id":"W3176432538","doi":"10.1609/aaai.v35i1.16087","title":"Towered Actor Critic For Handling Multiple Action Types In Reinforcement Learning For Drug Discovery","year":2021,"lang":"en","type":"article","venue":"Proceedings of the AAAI Conference on Artificial Intelligence","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Polytechnique Montréal; Mila - Quebec Artificial Intelligence Institute; Canadian Institute for Advanced Research; University of Alberta","funders":"University of Alberta; FedDev Ontario; Alberta Machine Intelligence Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institute for Advanced Research","keywords":"Reinforcement learning; Computer science; Pipeline (software); Action (physics); Artificial intelligence; Drug discovery; Space (punctuation); Machine learning; Programming language; Bioinformatics","score_opus":0.06874953863389731,"score_gpt":0.3136991647026755,"score_spread":0.24494962606877818,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176432538","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9373576,0.000076677,0.06102918,0.00037095151,0.00038354422,0.00050260685,0.000006435411,0.000008491599,0.0002644916],"genre_scores_gemma":[0.9976502,0.000086613174,0.0010021575,0.000058641082,0.00012374976,0.00008450271,0.000014739724,0.000014066809,0.00096535095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990848,0.000008656231,0.00029504814,0.000290841,0.000114764356,0.00020593486],"domain_scores_gemma":[0.99928784,0.000057267684,0.00014264848,0.00008236915,0.00040112503,0.000028726736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002640311,0.000119043245,0.00015040394,0.000034755634,0.00012212583,0.00009303196,0.00019292787,0.00007509128,0.000026164314],"category_scores_gemma":[0.0010456956,0.000100790785,0.000102332226,0.0000884942,0.000039422113,0.000020728832,0.00006997212,0.000098387456,0.0000012317915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029217394,0.000043926517,0.00011463816,0.00007885659,0.000014401917,5.3839035e-8,0.00021236725,0.0017319644,0.9795726,0.01220935,0.00003174876,0.005697901],"study_design_scores_gemma":[0.00007708619,0.00019580734,0.000011675322,0.00014713466,0.000011969423,5.9411906e-7,0.0014546291,0.02119871,0.9711199,0.005186909,0.0004747735,0.00012083836],"about_ca_topic_score_codex":0.000016009204,"about_ca_topic_score_gemma":0.00004673253,"teacher_disagreement_score":0.060292557,"about_ca_system_score_codex":0.000021668695,"about_ca_system_score_gemma":0.00008030762,"threshold_uncertainty_score":0.4110129},"labels":[],"label_agreement":null},{"id":"W3176482040","doi":"","title":"Effect of chronic haloperidol, endogenous dopamine, and selective D¦1 competitors on in vivo D¦1 receptor binding in rat brain","year":2000,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto","keywords":"Endogeny; Haloperidol; Pharmacology; Dopamine; In vivo; Dopamine receptor; Receptor; Chemistry; Neuroscience; Medicine; Psychology; Internal medicine; Biology","score_opus":0.005318691372257506,"score_gpt":0.22333526443730162,"score_spread":0.2180165730650441,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176482040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898862,0.0015993927,0.000005521977,0.000014284816,0.00020878516,0.00036726904,0.000031530275,0.0000051927536,0.007881776],"genre_scores_gemma":[0.99481416,0.0016576473,0.00008596598,0.000003000005,0.00005578403,0.0000014317869,0.00028668973,0.000023904026,0.0030714236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989451,0.00018332106,0.00013693189,0.0003866105,0.00013539547,0.00021261828],"domain_scores_gemma":[0.99951744,0.000052295592,0.00017852355,0.0001641628,0.00003639755,0.000051189058],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022444525,0.00023561394,0.00045065396,0.00010850335,0.000055371616,0.0000057866646,0.00017611944,0.0003401167,0.0018961143],"category_scores_gemma":[0.000024138968,0.00027871435,0.000101628895,0.00007492176,0.000044072047,0.000012347874,0.000030366284,0.00014810187,0.0000023387495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017539199,0.00006203345,0.00018265616,0.000239003,0.000051998617,0.000008906596,0.0019244228,0.00007556585,0.9835028,0.000014284774,0.00011162719,0.01207276],"study_design_scores_gemma":[0.0019766218,0.0035933098,0.0014267225,0.00048206604,0.00003841227,0.0000029002056,0.0037020461,0.000061161394,0.98711026,7.534766e-7,0.0012581291,0.00034763373],"about_ca_topic_score_codex":0.014359843,"about_ca_topic_score_gemma":0.058880698,"teacher_disagreement_score":0.044520855,"about_ca_system_score_codex":0.00024314584,"about_ca_system_score_gemma":0.000118594384,"threshold_uncertainty_score":0.9999665},"labels":[],"label_agreement":null},{"id":"W3176740709","doi":"10.1096/fasebj.20.4.a701-c","title":"Age‐dependent activation of lympho‐endothelial interactions in mice","year":2006,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Chemistry; Endothelial activation; Cell biology; Biophysics; Internal medicine; Biology; Endothelium; Medicine","score_opus":0.01179291245543935,"score_gpt":0.2468020871673966,"score_spread":0.23500917471195726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176740709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913734,0.000067035624,0.0072993087,0.00008072758,0.00020576867,0.000045759738,0.000004507944,0.0000016078311,0.0009218794],"genre_scores_gemma":[0.998615,0.000034992176,0.0003025754,0.000045966965,0.0003960554,0.0000020275645,0.0000104674455,0.000007067071,0.00058584317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994844,0.00006270149,0.0001860044,0.00007079562,0.000095566975,0.00010050794],"domain_scores_gemma":[0.9997404,0.00001255677,0.00011575213,0.0000765707,0.00003685555,0.000017841841],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022861015,0.000057610996,0.00006523636,0.00004038869,0.00006304159,0.000020153848,0.00011142467,0.000028956007,0.000089455854],"category_scores_gemma":[0.000018403272,0.000041316336,0.000058694357,0.00004182772,0.000018531877,0.000004863229,0.000022097318,0.00009877405,0.000002565741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059479826,0.000036873196,0.0002254347,0.0000015331141,0.0000110097935,0.000002800765,0.000041677435,0.0012914668,0.9972744,0.000111585905,0.00015518992,0.0007885754],"study_design_scores_gemma":[0.00038136553,0.00004186703,0.00043741942,0.000016843223,0.0000058398214,0.0000706879,0.00016233964,0.000077195284,0.9975045,0.0005389165,0.00071551703,0.000047507354],"about_ca_topic_score_codex":0.00013807583,"about_ca_topic_score_gemma":0.00006992735,"teacher_disagreement_score":0.0072416,"about_ca_system_score_codex":0.000022051745,"about_ca_system_score_gemma":0.000037961345,"threshold_uncertainty_score":0.16848314},"labels":[],"label_agreement":null},{"id":"W3176817180","doi":"10.1096/fasebj.2018.32.1_supplement.lb659","title":"Molecular Insights into Tachyphylaxis Phenomenon in the Angiotensin II Type 1 Receptor","year":2018,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Tachyphylaxis; Losartan; Angiotensin II; Chemistry; Internalization; Receptor; Internal medicine; Endocrinology; HEK 293 cells; Pharmacology; Biophysics; Biology; Biochemistry; Medicine","score_opus":0.01041377325659608,"score_gpt":0.2375267237856875,"score_spread":0.22711295052909142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176817180","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947585,0.0017536024,0.001471627,0.00060193025,0.00048271177,0.00010899501,8.8851596e-7,0.000004153588,0.00081757724],"genre_scores_gemma":[0.9967385,0.00019145747,0.0006901045,0.0010985791,0.0010767217,0.0000027079532,0.000011168509,0.000018424864,0.00017236291],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989636,0.00022257023,0.00020345814,0.00017278153,0.0002011962,0.00023641414],"domain_scores_gemma":[0.9993879,0.000012300955,0.00009525515,0.00031095973,0.0001342488,0.000059312173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057439593,0.0001367523,0.00010882448,0.00006396,0.0004280262,0.00006606045,0.00043916533,0.000095666255,0.00015661142],"category_scores_gemma":[0.000050253737,0.00007537886,0.00008745852,0.00024128388,0.000106711974,0.0000058863925,0.0000981766,0.00024006855,0.000033526125],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007199971,0.000031591993,0.000031814776,0.0000011267921,0.000029992229,0.00000801362,0.0016719957,0.000032848828,0.99412566,0.0002991804,0.0016779889,0.002017795],"study_design_scores_gemma":[0.000304698,0.000998471,0.000051391304,0.000015576587,0.000011986114,0.000071155344,0.00069451064,0.00007345888,0.9500086,0.0015172726,0.04611497,0.0001379474],"about_ca_topic_score_codex":0.000019307621,"about_ca_topic_score_gemma":0.000021114794,"teacher_disagreement_score":0.04443698,"about_ca_system_score_codex":0.000021180002,"about_ca_system_score_gemma":0.00006721969,"threshold_uncertainty_score":0.32920745},"labels":[],"label_agreement":null},{"id":"W3176988374","doi":"10.1096/fasebj.20.4.a455-c","title":"Protein interaction domains and biological complexity","year":2006,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Function (biology); Mechanism (biology); Protein–protein interaction; Signal transducing adaptor protein; Computational biology; Biology; Computer science; Cell biology; Signal transduction; Physics","score_opus":0.027163218248393194,"score_gpt":0.25546098874241896,"score_spread":0.22829777049402578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176988374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99129534,0.00022183213,0.0076479698,0.00020447528,0.0000911601,0.00006680535,0.0000025992094,0.0000039989704,0.0004658079],"genre_scores_gemma":[0.9982619,0.000034632256,0.00094805466,0.000076999626,0.0005011362,0.0000025934921,0.00001026159,0.000004640016,0.00015974038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995535,0.00008010537,0.000109605,0.00008725081,0.000058034653,0.00011151596],"domain_scores_gemma":[0.99980253,0.0000053775384,0.000063763335,0.000069805916,0.000025681233,0.000032868425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002527655,0.00006355841,0.000057360994,0.0000119969245,0.0001965188,0.000048841594,0.0000770813,0.000049087022,0.00008926196],"category_scores_gemma":[0.000011000118,0.00003673714,0.00004305572,0.000019596706,0.000067603,0.000002614319,0.00003818258,0.00012289158,0.0000034380582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004198747,0.00001471197,0.0002673357,8.6048374e-7,0.00000883413,0.000002365256,0.000007727487,0.000015195934,0.99756056,0.0011755138,0.0002001887,0.0007047374],"study_design_scores_gemma":[0.00027677932,0.00020484951,0.0015420233,0.000009181676,0.0000051480038,0.00033158346,0.00011795361,0.00007906015,0.98753834,0.0062050475,0.0036114445,0.00007859839],"about_ca_topic_score_codex":0.000015848882,"about_ca_topic_score_gemma":0.000008791313,"teacher_disagreement_score":0.010022211,"about_ca_system_score_codex":0.0000067588167,"about_ca_system_score_gemma":0.000010725443,"threshold_uncertainty_score":0.15114836},"labels":[],"label_agreement":null},{"id":"W3177118806","doi":"10.1096/fasebj.26.1_supplement.lb631","title":"Differential impact of three β‐adrenergic receptor antagonists on the vascular dysfunction of atherosclerotic mice","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Montreal Heart Institute","funders":"","keywords":"Nebivolol; Antagonist; Internal medicine; Medicine; Endocrinology; Propranolol; In vivo; Receptor antagonist; Endothelium; Endothelial dysfunction; Receptor; Vasodilation; Pharmacology; Cardiology; Biology; Blood pressure","score_opus":0.018060075811409955,"score_gpt":0.23780258167481755,"score_spread":0.2197425058634076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177118806","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99390644,0.0004645139,0.0049370625,0.000036261743,0.00046764113,0.00010286794,0.000011637763,0.0000023243485,0.00007122385],"genre_scores_gemma":[0.99900496,0.00018427627,0.00007459563,0.000025655307,0.00063690124,0.0000027782614,0.000010723368,0.000017380593,0.00004273025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990609,0.00016288192,0.00023904334,0.00009112086,0.00022131705,0.0002247265],"domain_scores_gemma":[0.9993108,0.000028790628,0.00025388756,0.0002596069,0.000076340584,0.000070586866],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050505484,0.00013307402,0.00015061136,0.000026740989,0.0001572211,0.000019027588,0.00024899215,0.000082033264,0.00066637946],"category_scores_gemma":[0.000038811744,0.00006447513,0.0003505949,0.000060455928,0.0000736769,0.000005719067,0.000044598903,0.00017000241,0.000006293367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013495902,0.00008117125,0.0020052514,0.0000044083718,0.00023541068,9.007743e-8,0.00008080725,0.00031018,0.99615586,0.00018343312,0.00020530274,0.0006031372],"study_design_scores_gemma":[0.00036664755,0.00052273367,0.004736302,0.000030337787,0.000067905465,0.000023677881,0.000070560054,0.00008157402,0.9938351,0.00009981261,0.00008286779,0.0000824981],"about_ca_topic_score_codex":0.00002476649,"about_ca_topic_score_gemma":0.0000020120222,"teacher_disagreement_score":0.0050984924,"about_ca_system_score_codex":0.000020079055,"about_ca_system_score_gemma":0.000043108408,"threshold_uncertainty_score":0.7296388},"labels":[],"label_agreement":null},{"id":"W3177252700","doi":"10.1096/fasebj.22.1_supplement.1157.4","title":"Caloxin 1c2‐ A Novel Engineered Selective Inhibitor of Plasma Membrane Ca <sup>2+</sup> ‐ Pump Isoform 4, Effects on Coronary Artery","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"McMaster University","funders":"","keywords":"Gene isoform; Extracellular; Endoplasmic reticulum; Homeostasis; Chemistry; Biochemistry; Cell biology; Biology; Gene","score_opus":0.008811365367364448,"score_gpt":0.20166803369237124,"score_spread":0.19285666832500678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177252700","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99621356,0.00015710451,0.0028829318,0.00007290131,0.00023827767,0.00019357912,0.000029784223,0.0000084573685,0.00020339353],"genre_scores_gemma":[0.9981285,0.00013903611,0.00045615132,0.00019655391,0.00072481675,0.000009521017,0.0000263841,0.000031751617,0.00028728254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882174,0.000081067265,0.00029619905,0.00020427113,0.00027097535,0.00032574],"domain_scores_gemma":[0.9993267,0.00007156135,0.0001444381,0.0002153338,0.000109943205,0.00013202243],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002938394,0.00021897984,0.00024664507,0.00007166851,0.00023889888,0.000016966307,0.0002322111,0.00015922537,0.00006211312],"category_scores_gemma":[0.00007608079,0.00015344442,0.0001914797,0.00009904401,0.00006477737,0.000008564456,0.00004923999,0.00035722292,0.000012409062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041788153,0.00010142062,0.000039105344,0.000017315146,0.00017427941,0.000046379373,0.0005245184,0.006127954,0.99135035,0.000016812017,0.0006150644,0.0005688957],"study_design_scores_gemma":[0.0015051633,0.0011886662,0.00011882305,0.00006256821,0.00003451985,0.0017392397,0.00016587644,0.0027505269,0.9919084,0.000024728513,0.00032284408,0.00017867527],"about_ca_topic_score_codex":0.000008412253,"about_ca_topic_score_gemma":0.0000017737447,"teacher_disagreement_score":0.003377427,"about_ca_system_score_codex":0.00003864243,"about_ca_system_score_gemma":0.00013343991,"threshold_uncertainty_score":0.62572813},"labels":[],"label_agreement":null},{"id":"W3177290310","doi":"10.1096/fasebj.2019.33.1_supplement.663.15","title":"NF1 dissociates cell type specific contributions toward reward valuation and motor control","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Medium spiny neuron; Regulator; Regulator of G protein signaling; Neuroscience; Neurofibromin 1; G protein-coupled receptor; Biology; Cell type; Striatum; Signal transduction; Neurofibromatosis; Cell biology; G protein; Cell; Gene; Genetics; Dopamine; GTPase-activating protein","score_opus":0.011286535849204374,"score_gpt":0.23357916917892563,"score_spread":0.22229263332972127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177290310","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899199,0.0020456403,0.0067309756,0.00043817045,0.00040842488,0.00020213702,0.000022649596,0.0000044445096,0.00022767602],"genre_scores_gemma":[0.99800855,0.00061062834,0.00015521824,0.00014774025,0.00037513647,0.0000031409697,0.0000210197,0.000010091578,0.0006685001],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934113,0.000108130174,0.00014683604,0.00011406617,0.00012355273,0.00016630172],"domain_scores_gemma":[0.99952406,0.00002622481,0.000104095234,0.00011268045,0.0001641304,0.00006883815],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00047453088,0.00008500024,0.000104411614,0.000017544913,0.00015226052,0.00008284072,0.000106187246,0.000074159594,0.00029327555],"category_scores_gemma":[0.000042277203,0.00005729567,0.00006821099,0.000034522905,0.000024174782,0.0000055906376,0.000024741257,0.00013411713,0.000048644666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000057546058,0.000012771517,0.0011215828,0.0000022847128,0.00003081421,5.607742e-7,0.000058307105,0.000065431705,0.99762225,0.000086026455,0.00064672885,0.00029571628],"study_design_scores_gemma":[0.0018952311,0.00063740945,0.003583909,0.000019687388,0.00005737281,0.000056574645,0.000537174,0.00052394095,0.9845212,0.0023630995,0.0056020035,0.00020240028],"about_ca_topic_score_codex":0.0000040092837,"about_ca_topic_score_gemma":4.979193e-7,"teacher_disagreement_score":0.013101033,"about_ca_system_score_codex":0.000018350542,"about_ca_system_score_gemma":0.00004367964,"threshold_uncertainty_score":0.32111615},"labels":[],"label_agreement":null},{"id":"W3177353644","doi":"10.1096/fasebj.22.1_supplement.1044.4","title":"Differential Contribution of G‐protein Coupled Receptor Kinase 2 and 3 in Regulating Structurally Related Human Dopamine D1 and D5 Receptors","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor kinase; Biology; Receptor; Beta adrenergic receptor kinase; Dopamine receptor; G protein-coupled receptor; Cell biology; Dopamine; Signal transduction; Endocrinology; Biochemistry","score_opus":0.007649583590687022,"score_gpt":0.21625158604477787,"score_spread":0.20860200245409086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177353644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99873984,0.00058110285,0.0003278224,0.00006566056,0.00011557402,0.00015147208,0.0000048465645,0.0000039270353,0.000009748916],"genre_scores_gemma":[0.9991658,0.0002005627,0.00030738916,0.000008960839,0.00012976551,0.000002457438,0.00004003226,0.000012307448,0.00013277351],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903744,0.00013626853,0.00035611578,0.00015731332,0.00013334777,0.00017951602],"domain_scores_gemma":[0.9994953,0.000013350394,0.00022802693,0.00010806807,0.00008401452,0.00007122098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030889446,0.00012713627,0.00018565246,0.000049048074,0.00031339985,0.000027740212,0.0000909093,0.00011452341,0.00015180424],"category_scores_gemma":[0.0000822971,0.00009065208,0.000048367718,0.000063556865,0.0001599813,0.000008290541,0.000058025456,0.0002090141,2.717988e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015048211,0.000013325624,0.0018978866,0.000005466621,0.000028544031,0.0000036195918,0.00012937293,0.000027968294,0.9970425,0.00010207125,0.000012124684,0.0005866861],"study_design_scores_gemma":[0.0015463344,0.00032107846,0.003535671,0.000066820874,0.000013762225,0.0001812452,0.000116998825,0.00032397543,0.9934269,0.00030228737,0.000041309497,0.00012361986],"about_ca_topic_score_codex":0.000024196856,"about_ca_topic_score_gemma":0.000012580025,"teacher_disagreement_score":0.0036155554,"about_ca_system_score_codex":0.000015901778,"about_ca_system_score_gemma":0.000030461364,"threshold_uncertainty_score":0.36966845},"labels":[],"label_agreement":null},{"id":"W3177382875","doi":"10.1096/fasebj.26.1_supplement.1093.5","title":"Age dependent cardiovascular responses to angiotensin II (ANG II) in conscious mice","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Angiotensin II; Mean arterial pressure; Blood pressure; Internal medicine; Endocrinology; Homeostasis; Vasodilation; Receptor; Renin–angiotensin system; Heart rate; Medicine; Vascular resistance; Chemistry","score_opus":0.016057094709281558,"score_gpt":0.24191018192358799,"score_spread":0.2258530872143064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177382875","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918478,0.0058490857,0.0013054032,0.0002764093,0.00043753814,0.00012368016,0.00000572485,0.0000049554747,0.00014940005],"genre_scores_gemma":[0.99683076,0.00017562097,0.0009895649,0.00051323185,0.000735304,0.000004266253,0.0000045002025,0.00001863353,0.00072810333],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99880546,0.00024353963,0.00020022344,0.00014575999,0.00022103154,0.00038396206],"domain_scores_gemma":[0.99944305,0.000016175922,0.00005381399,0.00026757014,0.00005305039,0.00016636417],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015064474,0.00012870516,0.00016847684,0.00006724536,0.00034918796,0.000036093985,0.00022548728,0.000092986775,0.0000543714],"category_scores_gemma":[0.000114271024,0.0000923399,0.00022447368,0.000082287945,0.000029925153,0.0000063524617,0.00018705915,0.00019847251,0.000012198946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000120911965,0.0000335104,0.00053703855,0.0000012518218,0.0001125374,0.000028424985,0.0005192143,0.00034010573,0.9959695,0.000020087862,0.00076664076,0.0015508122],"study_design_scores_gemma":[0.0004742678,0.00021345173,0.0013264099,0.000023331562,0.000048539347,0.000769043,0.00035978464,0.000008372424,0.97523063,0.00004469354,0.021326803,0.0001746691],"about_ca_topic_score_codex":0.000038890405,"about_ca_topic_score_gemma":0.00002299311,"teacher_disagreement_score":0.02073883,"about_ca_system_score_codex":0.00003119613,"about_ca_system_score_gemma":0.00005188113,"threshold_uncertainty_score":0.37655118},"labels":[],"label_agreement":null},{"id":"W3177391923","doi":"10.1096/fasebj.2019.33.1_supplement.810.3","title":"Contribution of cyclic AMP and β‐arrestin‐2‐dependent mechanisms to β <sub>2</sub> ‐adrenoceptor‐mediated gene expression changes in human airway epithelial cells","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Formoterol; Salmeterol; Cell biology; MAPK/ERK pathway; Internalization; Chemistry; Protein kinase A; Phosphorylation; Dephosphorylation; Kinase; Transfection; Signal transduction; Arrestin; G protein-coupled receptor; Pharmacology; Receptor; Endocrinology; Internal medicine; Biology; Medicine; Biochemistry; Gene","score_opus":0.0072616000805834045,"score_gpt":0.22047404857002587,"score_spread":0.21321244848944246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177391923","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99136776,0.00021982336,0.00759637,0.000087685556,0.0003795804,0.00029400253,0.000036547208,0.0000054096113,0.000012831777],"genre_scores_gemma":[0.99897885,0.000236089,0.00031373184,0.000109760156,0.00024034134,0.000008973058,0.00004495635,0.000020759842,0.00004654548],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987728,0.00017298394,0.00028809233,0.00023559835,0.00024016415,0.00029035285],"domain_scores_gemma":[0.9993217,0.000026903723,0.00021239958,0.0002039393,0.000100230245,0.00013483416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074618775,0.00016585273,0.00021892278,0.000089583285,0.00012556826,0.00003512799,0.00020437334,0.00014734917,0.00011706643],"category_scores_gemma":[0.000049846352,0.00012119812,0.000062405285,0.00007537296,0.000028927114,0.0000066296143,0.00012594237,0.00020089227,0.000015565036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012743489,0.000035411835,0.00014693303,0.0000065687627,0.00001761272,0.0000028827249,0.0001700783,0.00024746,0.99874014,0.000031157422,0.00004625638,0.00042808376],"study_design_scores_gemma":[0.00096790044,0.00045071793,0.00014534505,0.0000619724,0.00001357869,0.00003129682,0.00012888499,0.000026158643,0.99767965,0.00026845682,0.000074586016,0.00015143241],"about_ca_topic_score_codex":0.000010889016,"about_ca_topic_score_gemma":0.000047295576,"teacher_disagreement_score":0.007611093,"about_ca_system_score_codex":0.000027017959,"about_ca_system_score_gemma":0.000037158163,"threshold_uncertainty_score":0.4942316},"labels":[],"label_agreement":null},{"id":"W3177411842","doi":"10.1096/fasebj.27.1_supplement.1165.2","title":"Effects of a (pro)renin receptor blocker on weight gain in obese mice","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Internal medicine; Endocrinology; Leptin; Adipocyte; White adipose tissue; Resistin; Adipose tissue; Chemistry; Weight gain; Obesity; Biology; Medicine; Adipokine; Body weight","score_opus":0.005898368103495999,"score_gpt":0.21339132895667876,"score_spread":0.20749296085318275,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177411842","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978388,0.00078372605,0.0004905246,0.00020703537,0.0002497655,0.00018626456,0.0000017711676,0.0000026243426,0.00023948301],"genre_scores_gemma":[0.99795413,0.00026627947,0.0006269893,0.00020707917,0.00028408266,0.000014991307,0.0000040728596,0.000016075524,0.0006263105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99910283,0.00017233711,0.00022417103,0.00013468895,0.00014978283,0.00021618085],"domain_scores_gemma":[0.9995518,0.000042796106,0.00012475533,0.00014628386,0.000060206654,0.00007417054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035387778,0.00011985591,0.00013771997,0.00005100205,0.00006564457,0.000026034031,0.00022745233,0.00009487578,0.00034848743],"category_scores_gemma":[0.00007693901,0.000075565586,0.00009837694,0.00007349256,0.000034772405,0.000004254218,0.00004301334,0.00022424056,0.000044773486],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006864771,0.000065641245,0.00020134957,0.000010388577,0.000028843,0.0000034917662,0.00012026583,0.000045672692,0.995069,0.000046085865,0.0022286994,0.0021118976],"study_design_scores_gemma":[0.0006594123,0.0003361561,0.00029385037,0.00008300039,0.000009580386,0.000024918132,0.000072173585,0.000103620805,0.9971986,0.00026122385,0.0008601891,0.00009729311],"about_ca_topic_score_codex":0.000028810924,"about_ca_topic_score_gemma":0.000004760633,"teacher_disagreement_score":0.002129565,"about_ca_system_score_codex":0.000014565007,"about_ca_system_score_gemma":0.000038449303,"threshold_uncertainty_score":0.38156933},"labels":[],"label_agreement":null},{"id":"W3177436779","doi":"10.1096/fasebj.25.1_supplement.1026.3","title":"Functional characteristics of alpha adrenoceptors in isolated pressurized rat mesenteric small veins","year":2011,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Yohimbine; Prazosin; Phenylephrine; Phentolamine; Mesenteric arteries; Clonidine; Vasoconstriction; Chemistry; Endocrinology; Internal medicine; Antagonist; Norepinephrine; Mesenteric Vein; Adrenergic receptor; Adrenergic; Medicine; Blood pressure; Propranolol; Receptor; Artery","score_opus":0.02504816100520468,"score_gpt":0.21143055926251694,"score_spread":0.18638239825731226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177436779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898103,0.0002604278,0.008989695,0.000022600856,0.000577668,0.00007804958,0.000008820323,0.0000035139517,0.00024892992],"genre_scores_gemma":[0.9987022,0.000181148,0.0003777919,0.00006133587,0.00022927178,0.0000030463918,0.000024792835,0.000015024619,0.00040538854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915576,0.000114026305,0.00031570482,0.00012114486,0.00011047471,0.00018287869],"domain_scores_gemma":[0.99947757,0.000010130077,0.00020568793,0.00014810495,0.00009586168,0.00006266634],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035108597,0.00011321217,0.00015581542,0.00005133407,0.000074730066,0.00001727663,0.00020332233,0.00008504916,0.00084745855],"category_scores_gemma":[0.0000356518,0.0000794654,0.000104794,0.00007133991,0.00004731681,0.0000048431903,0.00005851476,0.00017670043,0.000005769816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042455745,0.00010179138,0.0024293412,0.000005381398,0.0000626379,0.000007049905,0.0002766158,0.000013475783,0.9957305,0.000024565888,0.00015455838,0.00076952047],"study_design_scores_gemma":[0.0008104093,0.00046044623,0.006100759,0.000029086761,0.000030797964,0.00011475499,0.00013448062,0.00015765487,0.99129134,0.00011451509,0.00063428405,0.00012145532],"about_ca_topic_score_codex":0.000015110027,"about_ca_topic_score_gemma":0.0000071926743,"teacher_disagreement_score":0.008891906,"about_ca_system_score_codex":0.00000722878,"about_ca_system_score_gemma":0.00005882961,"threshold_uncertainty_score":0.9279077},"labels":[],"label_agreement":null},{"id":"W3177709612","doi":"10.1093/ijnp/pyw044.545","title":"PT545. The Direct Protein-Protein Interaction between Dopamine Transporter and Dopamine D2 Receptor: A Novel Target Site to Modulate Synaptic Dopamine","year":2016,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Dopamine transporter; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine receptor D2; Dopamine receptor D3; Neuroscience; Dopamine receptor; Dopamine receptor D1; Chemistry; Dopaminergic; Biology","score_opus":0.014244690595880015,"score_gpt":0.2767185134813889,"score_spread":0.26247382288550886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177709612","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9782111,0.00017690213,0.008448693,0.011282753,0.0013344933,0.0003880048,0.000063104584,0.000009064787,0.000085890904],"genre_scores_gemma":[0.9957191,0.00015723219,0.00064073526,0.0009035028,0.0017331009,0.00002600789,0.000011418294,0.00003783841,0.00077106315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983229,0.00018197804,0.0005837171,0.00031362553,0.0003456543,0.00025213952],"domain_scores_gemma":[0.99874157,0.000099220946,0.00042099875,0.00019963137,0.00040525987,0.00013331],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062566146,0.0002338938,0.00025437275,0.00012883724,0.000092878916,0.000047849197,0.0006789363,0.00008287021,0.00027500375],"category_scores_gemma":[0.000118918106,0.00012347667,0.00013802304,0.00010302219,0.00010444543,0.000028668952,0.000121756864,0.00026411592,0.000018960578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012843221,0.00007369213,0.00022199377,0.000004405286,0.00037208744,0.000023867966,0.00004531524,0.00011619508,0.991632,0.000021511745,0.00045092904,0.0057536867],"study_design_scores_gemma":[0.0028075238,0.0014159671,0.0019013124,0.00010819675,0.00009112021,0.00038059472,0.000031430976,0.0000925902,0.9300805,0.00009754362,0.0627354,0.00025783264],"about_ca_topic_score_codex":0.000008368349,"about_ca_topic_score_gemma":0.000004054301,"teacher_disagreement_score":0.06228447,"about_ca_system_score_codex":0.000039114748,"about_ca_system_score_gemma":0.00004296516,"threshold_uncertainty_score":0.50352323},"labels":[],"label_agreement":null},{"id":"W3179049916","doi":"10.31234/osf.io/zmpaq","title":"Dream to explore: 5-HT2a as adaptive temperature parameter for sophisticated affective inference","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Inference; Adversarial system; Computer science; Artificial intelligence; Psychology; Dream; Machine learning; Cognitive psychology; Cognitive science; Neuroscience","score_opus":0.040872853454524495,"score_gpt":0.3108277834279884,"score_spread":0.2699549299734639,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179049916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7345727,0.0005432163,0.26102903,0.00026973357,0.000942483,0.0016760298,0.00011785002,0.000050025083,0.0007989422],"genre_scores_gemma":[0.9660334,0.00010429755,0.029278489,0.0008364481,0.00042601622,0.00087526144,0.0011173906,0.0000629817,0.0012657004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979951,0.00010927049,0.00026876116,0.0010989242,0.00016719024,0.00036078802],"domain_scores_gemma":[0.998485,0.000099025914,0.00010716513,0.0006027657,0.0005096325,0.00019638943],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00020170173,0.00043115174,0.0004330417,0.00006306217,0.00009328939,0.0001531848,0.00033086966,0.00079156127,0.00024979122],"category_scores_gemma":[0.0007650775,0.00038838433,0.00030131062,0.00008438404,0.00003613267,0.0000029852063,0.00066952064,0.00034719234,0.000016593072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024298084,0.000087399516,0.000010697318,0.00005706502,0.00029279306,0.0000069486323,0.00031294976,0.0005944755,0.99396914,0.00081212533,0.0018830252,0.001730417],"study_design_scores_gemma":[0.0003054004,0.0008063983,0.000020325755,0.00012735663,0.00006988548,0.0000048632805,0.00068883545,0.0003060303,0.9928451,0.002447126,0.0017803367,0.00059835287],"about_ca_topic_score_codex":0.00004910964,"about_ca_topic_score_gemma":0.000030519266,"teacher_disagreement_score":0.23175055,"about_ca_system_score_codex":0.00004310979,"about_ca_system_score_gemma":0.0003339098,"threshold_uncertainty_score":0.9998568},"labels":[],"label_agreement":null},{"id":"W3179310865","doi":"10.1039/d1sc01753e","title":"State-selective frustration as a key driver of allosteric pluripotency","year":2021,"lang":"en","type":"article","venue":"Chemical Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Allosteric regulation; Chemistry; Allosteric enzyme; Allosteric modulator; Biophysics; Receptor; Biochemistry; Biology","score_opus":0.007146804043778792,"score_gpt":0.2411714960892275,"score_spread":0.2340246920454487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179310865","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962276,0.000099739365,0.0014995435,0.000048515256,0.00006318568,0.000040692503,0.0000023532662,0.0000038223634,0.0020145208],"genre_scores_gemma":[0.9974033,0.000027703385,0.0021571016,0.00008214358,0.000037112495,0.000003029426,0.000011206658,0.0000038474514,0.00027455352],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99925935,0.000010955284,0.00011162091,0.00027874776,0.0001813363,0.00015796146],"domain_scores_gemma":[0.9995479,0.000005061307,0.000044494467,0.00013251699,0.00019872797,0.00007132111],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010968901,0.000060940358,0.00007047482,0.000013881758,0.00004208116,0.000018266452,0.00014989334,0.00004804504,0.00010308016],"category_scores_gemma":[0.00016794415,0.00005558074,0.000037826943,0.00023185252,0.00015130788,0.000006917755,0.00009005526,0.000045213183,0.0000062252893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009454045,0.000023805236,0.000087390545,0.000003581312,0.000003587606,0.0000016413883,0.00007177075,0.0000070593173,0.9984004,0.00017604911,0.00005845657,0.0011567894],"study_design_scores_gemma":[0.00009771149,0.000066029075,0.00013143523,0.000007046739,0.0000028740371,0.0000087912595,0.000041796913,0.000051411793,0.9977005,0.0012748506,0.00054460677,0.000072955816],"about_ca_topic_score_codex":0.000009214045,"about_ca_topic_score_gemma":0.0000016303269,"teacher_disagreement_score":0.0017399674,"about_ca_system_score_codex":0.000015067897,"about_ca_system_score_gemma":0.00023249461,"threshold_uncertainty_score":0.22665168},"labels":[],"label_agreement":null},{"id":"W3179639426","doi":"10.1093/cercor/bhab224","title":"The Orphan GPCR Receptor, GPR88, Interacts with Nuclear Protein Partners in the Cerebral Cortex","year":2021,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Centre National de la Recherche Scientifique","keywords":"Cell biology; Nuclear localization sequence; Subcellular localization; Proximity ligation assay; Nuclear transport; Nucleus accumbens; Nuclear membrane; G protein-coupled receptor; Orphan receptor; Biology; Medium spiny neuron; Chemistry; Neuroscience; Cell nucleus; Receptor; Nucleus; Cytoplasm; Biochemistry; Gene; Central nervous system; Transcription factor; Basal ganglia; Signal transduction","score_opus":0.010109437515217671,"score_gpt":0.2426600732236767,"score_spread":0.23255063570845902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3179639426","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946509,0.00039568913,0.00011377736,0.00093242485,0.0002781132,0.00042158115,0.000009231888,0.000020312724,0.0031779802],"genre_scores_gemma":[0.995785,0.00006214348,0.00046657943,0.00097609643,0.0002849869,0.000055244203,0.0001218324,0.000050197956,0.002197917],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981255,0.00025820843,0.0003105344,0.00052402285,0.00028796447,0.0004937803],"domain_scores_gemma":[0.9989899,0.00003074589,0.00013499851,0.0006189085,0.00012249559,0.00010298657],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035587835,0.00026167757,0.00020254441,0.00002600439,0.00030481417,0.00021100322,0.0004887333,0.00015711295,0.0004921456],"category_scores_gemma":[0.000092890994,0.00015438824,0.00012571216,0.00022771994,0.00012835095,0.000014632248,0.00015315987,0.00032390968,0.00006209027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003097111,0.00011895955,0.00085679785,0.000019535335,0.00009124791,0.00004704545,0.0004972366,0.000013207895,0.9840072,0.0038558927,0.005537025,0.0046461686],"study_design_scores_gemma":[0.0026724376,0.0016410872,0.007880425,0.00022501583,0.00006087538,0.00022105365,0.008084033,0.00034842562,0.6254838,0.00082821416,0.35148826,0.0010663663],"about_ca_topic_score_codex":0.000044661178,"about_ca_topic_score_gemma":0.0004185393,"teacher_disagreement_score":0.35852337,"about_ca_system_score_codex":0.000028574119,"about_ca_system_score_gemma":0.00016073503,"threshold_uncertainty_score":0.629577},"labels":[],"label_agreement":null},{"id":"W3181052154","doi":"10.3390/biom11070979","title":"Receptor Interactions of Angiotensin II and Angiotensin Receptor Blockers—Relevance to COVID-19","year":2021,"lang":"en","type":"article","venue":"Biomolecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"General Secretariat for Research and Technology; Victoria University","keywords":"Angiotensin II; Candesartan; Angiotensin II receptor type 1; Receptor; Vasoconstriction; Angiotensin receptor; Chemistry; Pharmacology; Renin–angiotensin system; Internal medicine; Endocrinology; Medicine; Blood pressure","score_opus":0.01595368972760123,"score_gpt":0.27936381571145513,"score_spread":0.2634101259838539,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3181052154","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96809596,0.0030404064,0.016916422,0.010866753,0.0005684844,0.00023321273,0.00014644292,0.00003209306,0.000100220605],"genre_scores_gemma":[0.86695457,0.00067339645,0.12584835,0.0032399695,0.00040048524,0.000020211735,0.0003237074,0.00006123512,0.0024780747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987385,0.00008326016,0.00027338177,0.0005079498,0.00014517186,0.00025173576],"domain_scores_gemma":[0.9990082,0.000029184332,0.000098901066,0.0003480374,0.00023155473,0.00028416113],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013547664,0.00019224022,0.0002259489,0.00008056845,0.00015886387,0.00002878611,0.00011936762,0.0001384013,0.00023796636],"category_scores_gemma":[0.0005242406,0.00019724396,0.00013152574,0.00024285934,0.00010510533,0.0000056442855,0.00023540301,0.0000707425,0.000015699452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000802141,0.00006704055,0.000061771636,0.000015152352,0.00006642157,0.0000070718293,0.00016272062,0.000015640022,0.94894856,0.00029690156,0.04800267,0.0022758346],"study_design_scores_gemma":[0.00022795094,0.00016922363,0.000022424336,0.000026757461,0.000013890496,0.000029186109,0.0001716464,0.00001647507,0.6469879,0.00004059444,0.35213456,0.00015939825],"about_ca_topic_score_codex":0.00006538683,"about_ca_topic_score_gemma":0.000075421725,"teacher_disagreement_score":0.3041319,"about_ca_system_score_codex":0.000028829809,"about_ca_system_score_gemma":0.00017913576,"threshold_uncertainty_score":0.80433756},"labels":[],"label_agreement":null},{"id":"W3182504737","doi":"10.1007/s00360-021-01387-5","title":"In vivo cardiopulmonary impact of skeletal M3Dq DREADD expression: a pilot study","year":2021,"lang":"en","type":"article","venue":"Journal of Comparative Physiology B","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen's University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Torpor; Internal medicine; Endocrinology; Skeletal muscle; Ventilation (architecture); Receptor; Muscarinic acetylcholine receptor; Heart rate; Medicine; Biology; Thermoregulation; Blood pressure","score_opus":0.030462986075713953,"score_gpt":0.3319614613536377,"score_spread":0.3014984752779237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3182504737","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981374,0.0011088267,0.00023286697,0.000010780477,0.00019249482,0.000089482506,0.000008428585,9.560571e-7,0.00021874835],"genre_scores_gemma":[0.9992124,0.000056833218,0.0003448843,0.00001942251,0.00028683562,0.000003731984,0.0000049569753,0.000008128853,0.000062850035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986733,0.0004086896,0.00045088152,0.00017815157,0.00013267969,0.0001562977],"domain_scores_gemma":[0.9991098,0.00003456841,0.00033128483,0.00017945594,0.00028273897,0.00006212495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021773817,0.0001455844,0.0005602488,0.00006562596,0.000029624163,0.0000054371785,0.00016093192,0.00005367924,0.00023398778],"category_scores_gemma":[0.000023885132,0.00010965922,0.0002361111,0.00010831826,0.00005430151,0.000010739744,0.00008654465,0.0001761738,0.0000013517232],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069229264,0.0008679164,0.002753509,0.000005115056,0.0002356593,0.00004857841,0.0002846463,0.0018165692,0.992198,0.000011107124,0.0010689447,0.000017670029],"study_design_scores_gemma":[0.0012652342,0.0083401445,0.023512263,0.0000388477,0.000023709614,0.00010260107,0.0009973629,0.000027468868,0.96502364,0.00030306986,0.00024018167,0.00012546845],"about_ca_topic_score_codex":0.0000104379515,"about_ca_topic_score_gemma":0.000006606286,"teacher_disagreement_score":0.027174344,"about_ca_system_score_codex":0.000019618357,"about_ca_system_score_gemma":0.00018307286,"threshold_uncertainty_score":0.44717732},"labels":[],"label_agreement":null},{"id":"W3183177352","doi":"10.3389/fendo.2021.681646","title":"Mouse Spexin: (I) NMR Solution Structure, Docking Models for Receptor Binding, and Histological Expression at Tissue Level","year":2021,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Health and Medical Research Fund; Directorate for Biological Sciences; University of Alberta","keywords":"Receptor; G protein-coupled receptor; Docking (animal); Homology modeling; Random coil; Biology; Biochemistry; Biophysics; Chemistry; Protein secondary structure; Cell biology; Enzyme; Medicine","score_opus":0.02867227447711724,"score_gpt":0.25663791451509077,"score_spread":0.22796564003797354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183177352","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78067374,0.0041660876,0.21360584,0.00011321787,0.0009848687,0.00021751969,0.000116513416,0.000016638982,0.00010559279],"genre_scores_gemma":[0.8680333,0.0010530836,0.12746617,0.00013799564,0.00023461133,0.000050967465,0.0006145503,0.000035478446,0.0023738667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985587,0.0000929484,0.0002439895,0.0005699041,0.000081505765,0.00045293884],"domain_scores_gemma":[0.99955374,0.00001405556,0.00009149572,0.00021603408,0.000056051165,0.00006863813],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000069072135,0.00018362206,0.00027352906,0.00008583147,0.00014067227,0.000015749747,0.0001302543,0.0002824584,0.000080606],"category_scores_gemma":[0.00008237708,0.00018024794,0.00005835682,0.000055745204,0.00008494666,0.000009500248,0.00022886964,0.00012930516,0.0000014386508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014737644,0.000024630306,0.00091754395,0.000021224905,0.000023653154,0.000010935763,0.000057527937,0.0005264193,0.98169065,0.00032788195,0.010659228,0.00559293],"study_design_scores_gemma":[0.00090686115,0.00015854884,0.000034099434,0.000013002856,0.000010946495,0.00006308594,0.00012456157,0.0013892627,0.94758546,0.0016214203,0.047874883,0.00021785815],"about_ca_topic_score_codex":0.0000085794245,"about_ca_topic_score_gemma":0.000033770204,"teacher_disagreement_score":0.087359555,"about_ca_system_score_codex":0.00008049879,"about_ca_system_score_gemma":0.00003768899,"threshold_uncertainty_score":0.73502976},"labels":[],"label_agreement":null},{"id":"W3183689042","doi":"10.1096/fasebj.31.1_supplement.1053.17","title":"Genetic deletion of mu opioid receptors from Kölliker‐Fuse neurons reduces morphine‐induced respiratory depression","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institutes of Health","keywords":"Opioid; Receptor; Morphine; μ-opioid receptor; Agonist; Respiratory system; Pharmacology; Respiratory rate; Opioid receptor; Chemistry; Endocrinology; Population; Internal medicine; Medicine; Anesthesia; Heart rate; Blood pressure","score_opus":0.024737070701362527,"score_gpt":0.2623070378583014,"score_spread":0.23756996715693887,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3183689042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99666405,0.00096413045,0.0010244263,0.00009796613,0.0010117359,0.00010755953,0.000013320446,0.000005745379,0.000111060835],"genre_scores_gemma":[0.9974188,0.000444978,0.0008587051,0.00011202672,0.0010438889,0.0000047719236,0.00001014516,0.000027180447,0.000079465244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988031,0.00017723358,0.00032979215,0.00023755254,0.00023564773,0.00021672185],"domain_scores_gemma":[0.99862224,0.000019669698,0.00051872304,0.0006087142,0.000112162495,0.00011850432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003869992,0.0001611908,0.00016789956,0.00003892732,0.00063986314,0.000111151174,0.000655127,0.00014316323,0.00018525352],"category_scores_gemma":[0.00017465887,0.000112703834,0.00015013308,0.000026042511,0.00008881374,0.00001327936,0.00015839061,0.00025577183,0.000007470051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009513774,0.00002717364,0.003077806,0.000002561866,0.000041695308,0.000005868457,0.000071957445,0.000107986954,0.9875873,0.0000034920524,0.0006906477,0.00828837],"study_design_scores_gemma":[0.0004657691,0.00021316056,0.010372776,0.000049821083,0.000039199793,0.000027132919,0.000082579834,0.00007434755,0.9869612,0.0002471536,0.0013316156,0.00013524873],"about_ca_topic_score_codex":0.000073110336,"about_ca_topic_score_gemma":0.000011992544,"teacher_disagreement_score":0.008153121,"about_ca_system_score_codex":0.000012254741,"about_ca_system_score_gemma":0.000091283,"threshold_uncertainty_score":0.49213746},"labels":[],"label_agreement":null},{"id":"W3184495619","doi":"10.1016/j.sbi.2021.06.014","title":"Insane in the membrane: developments in protein folding, protein transport, and signaling by GPCRs","year":2021,"lang":"en","type":"editorial","venue":"Current Opinion in Structural Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Australian Research Council","keywords":"G protein-coupled receptor; Folding (DSP implementation); Membrane protein; Protein folding; Chemistry; Cell biology; Computational biology; Biophysics; Membrane; Signal transduction; Biology; Biochemistry; Engineering","score_opus":0.015931385577916336,"score_gpt":0.30121115333057236,"score_spread":0.285279767752656,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3184495619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84877735,0.012144551,0.000022360502,0.000041493768,0.13768217,0.0011751064,0.00013534428,0.000005607496,0.000015983076],"genre_scores_gemma":[0.93243295,0.0027300478,0.000328091,0.00001739261,0.055278018,0.00060040917,0.008530063,0.000052943265,0.000030072006],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9971271,0.00044216696,0.00079639984,0.0008867395,0.00022450404,0.00052304746],"domain_scores_gemma":[0.9994062,0.00005535504,0.00021541337,0.00022166403,0.000050664406,0.00005067389],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00065397046,0.00043228548,0.0005466794,0.00021047838,0.000046314115,0.00003113717,0.00041370184,0.0009971616,0.000032511372],"category_scores_gemma":[0.00018711515,0.0003455125,0.00007353171,0.00028047853,0.0000891937,0.000009414579,0.000105686246,0.00096911186,4.5377118e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029576657,0.00008874462,0.005722752,0.0009183637,0.000034516415,0.000013235404,0.000700077,0.000041190804,0.9794268,0.00021739016,0.005227473,0.007313685],"study_design_scores_gemma":[0.007953436,0.0008290236,0.0015846451,0.0048085256,0.000015665084,0.000015861955,0.000715393,0.00006198161,0.19154501,0.0012362547,0.7888642,0.002370001],"about_ca_topic_score_codex":0.00019482627,"about_ca_topic_score_gemma":0.00023138577,"teacher_disagreement_score":0.7878818,"about_ca_system_score_codex":0.00007509629,"about_ca_system_score_gemma":0.00026186672,"threshold_uncertainty_score":0.9998997},"labels":[],"label_agreement":null},{"id":"W3185055134","doi":"10.82308/11364","title":"Searching for an exclusion mechanism in the evolution of neurotransmitter receptor subunits","year":2021,"lang":"en","type":"article","venue":"eScholarship@McGill (McGill)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mechanism (biology); Neurotransmitter; Neurotransmitter receptor; Glycine receptor; Receptor; Chemistry; Neuroscience; Biology; Biochemistry; Amino acid; Glycine; Philosophy; Epistemology","score_opus":0.02306428997183063,"score_gpt":0.2536457444344782,"score_spread":0.23058145446264755,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185055134","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974514,0.00018926001,0.00035970216,0.000050862,0.000266906,0.00044448322,0.0001682523,0.000015338686,0.001053782],"genre_scores_gemma":[0.996047,0.000109030465,0.002977638,0.00037026568,0.00006621222,0.00006584179,0.00017051164,0.000050204108,0.0001432776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977676,0.0005946131,0.00038817426,0.00055232947,0.0003135776,0.0003836971],"domain_scores_gemma":[0.9989774,0.00007112306,0.000117243464,0.0004895612,0.00024803483,0.00009662544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012882749,0.00021808974,0.00021822914,0.00009009895,0.0004021629,0.000024688248,0.00039264263,0.00023470416,0.000060589507],"category_scores_gemma":[0.00028234432,0.00019121463,0.00017529754,0.00026736685,0.00003059287,0.000036004854,0.00012967392,0.0003115256,0.000004788278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009787229,0.00012387574,0.0000137665,0.000044686894,0.000017794,0.000004149351,0.000012520701,0.0000821093,0.93667823,0.049985494,0.0000020563732,0.01293744],"study_design_scores_gemma":[0.0007227687,0.00047455932,0.000091737704,0.000052513846,0.000019972378,0.000022499216,0.00038309107,0.00016144924,0.96542645,0.02175519,0.010653388,0.00023635993],"about_ca_topic_score_codex":0.00011362451,"about_ca_topic_score_gemma":0.00026906768,"teacher_disagreement_score":0.028748237,"about_ca_system_score_codex":0.000073980256,"about_ca_system_score_gemma":0.00005269154,"threshold_uncertainty_score":0.77975065},"labels":[],"label_agreement":null},{"id":"W3185799549","doi":"","title":"Measuring Conformational Selection in G Protein-Coupled Receptors by Single-Molecule Förster Resonance Energy Transfer","year":2021,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Förster resonance energy transfer; Fluorescence in the life sciences; Fluorescence; Fluorescence correlation spectroscopy; Alexa Fluor; Chemistry; Fluorescence cross-correlation spectroscopy; Biophysics; Microscopy; Fluorescence anisotropy; Fluorescence microscope; Fluorescence spectroscopy; Fluorophore; Molecule; Membrane; Biology; Biochemistry; Optics","score_opus":0.012555536394878154,"score_gpt":0.19473446342923065,"score_spread":0.18217892703435248,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3185799549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8818105,0.0008574094,0.11414363,0.00012097578,0.000110030174,0.00013155419,0.0000053539266,0.000019526733,0.002801052],"genre_scores_gemma":[0.99440396,0.000049929262,0.0012107915,0.0002867206,0.00007989342,0.000046308895,0.00015749269,0.000019967494,0.0037449584],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900925,0.000057955844,0.00025068433,0.00028817987,0.00017036259,0.00022359352],"domain_scores_gemma":[0.99970937,0.0000045033726,0.000024835459,0.00009121742,0.00011813313,0.00005196347],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013452397,0.00013271531,0.0001189787,0.00003463237,0.000058089816,0.000039516857,0.00007359881,0.00014774782,0.00053385826],"category_scores_gemma":[0.000025572785,0.00013420764,0.00006572108,0.00013919554,0.000015531969,0.000010757005,0.000023054037,0.00007292057,0.0000042457687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004475269,0.000056430697,0.00005789316,0.000007996949,0.000011969099,0.0000012257888,0.000027384047,0.000056636534,0.9973466,0.0006416135,0.00040426603,0.0013432686],"study_design_scores_gemma":[0.00050567253,0.000094581446,0.000016272603,0.000023258905,0.000002673254,0.000009456764,0.00005277593,0.00077735406,0.9646846,0.000042122636,0.033615496,0.00017570615],"about_ca_topic_score_codex":0.00004269767,"about_ca_topic_score_gemma":0.00017107753,"teacher_disagreement_score":0.11293284,"about_ca_system_score_codex":0.00003233327,"about_ca_system_score_gemma":0.00008087886,"threshold_uncertainty_score":0.5845373},"labels":[],"label_agreement":null},{"id":"W3186495549","doi":"10.1039/d1sc00749a","title":"Mechanistic insights into dopaminergic and serotonergic neurotransmission – concerted interactions with helices 5 and 6 drive the functional outcome","year":2021,"lang":"en","type":"article","venue":"Chemical Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Instituto de Salud Carlos III; Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España; Ministerio de Ciencia e Innovación; Ministerio de Ciencia, Innovación y Universidades","keywords":"Serotonergic; Dopaminergic; Neuroscience; Neurotransmitter; Neurotransmission; Transmembrane domain; Neurotransmitter receptor; Helix (gastropod); Chemistry; Receptor; Biology; Dopamine; Serotonin; Biochemistry; Central nervous system; Ecology","score_opus":0.013201677635164367,"score_gpt":0.2520683219907322,"score_spread":0.23886664435556784,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3186495549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936598,0.0003585899,0.00534713,0.0003055628,0.00008211724,0.00007186093,7.766724e-7,0.000007098667,0.00016707162],"genre_scores_gemma":[0.9988078,0.00007059019,0.00065036956,0.00025620408,0.000050571813,0.000014617883,0.00000996531,0.000005309195,0.00013459972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992324,0.0000183942,0.00010159085,0.00036224016,0.00015682122,0.0001285249],"domain_scores_gemma":[0.99960095,0.000026120342,0.00003459021,0.00012775978,0.000101847254,0.00010875488],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000073719486,0.00009365655,0.000077811346,0.000015865928,0.00025206147,0.00006945514,0.000100890495,0.00003620493,0.00004297041],"category_scores_gemma":[0.0000525133,0.00005561951,0.000018032459,0.00015210094,0.00032049223,0.000012317171,0.00010934929,0.000088597364,0.0000010382976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018754377,0.000011182328,0.00020192734,0.00000694294,0.0000047268195,0.0000029297423,0.00006224207,0.000013367726,0.99861014,0.00053145585,0.00000850471,0.0005278168],"study_design_scores_gemma":[0.0001975606,0.00006006584,0.0005019292,0.0000141479395,0.000011397472,0.00007290701,0.00016769725,0.0011746631,0.9954145,0.0004297444,0.0018582874,0.00009708583],"about_ca_topic_score_codex":0.000011654518,"about_ca_topic_score_gemma":0.000011278178,"teacher_disagreement_score":0.00514798,"about_ca_system_score_codex":0.000008719383,"about_ca_system_score_gemma":0.00006396163,"threshold_uncertainty_score":0.22680977},"labels":[],"label_agreement":null},{"id":"W3187230085","doi":"10.3390/molecules26164767","title":"In Silico Identification of Tripeptides as Lead Compounds for the Design of KOR Ligands","year":2021,"lang":"en","type":"article","venue":"Molecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Ministero della Salute","keywords":"In silico; Virtual screening; Tripeptide; Computational biology; Identification (biology); Drug discovery; Lead (geology); Workflow; Chemistry; Novelty; DrugBank; Pharmacology; Combinatorial chemistry; Computer science; Drug; Bioinformatics; Peptide; Medicine; Biology; Biochemistry; Database","score_opus":0.018852943501190076,"score_gpt":0.27165463947635016,"score_spread":0.25280169597516006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3187230085","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8186691,0.0020988907,0.1786669,0.00017215131,0.00010317681,0.00021075054,0.000013380111,0.0000022800052,0.0000634055],"genre_scores_gemma":[0.9972448,0.0001882578,0.0019874095,0.00007523494,0.000035941735,0.00003127316,0.000031749973,0.000009920264,0.00039545746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993988,0.000037278627,0.00024721248,0.00014968256,0.000077608194,0.000089385714],"domain_scores_gemma":[0.9995183,0.00005448532,0.000102316735,0.00019330696,0.00011901822,0.000012579212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026398004,0.000066457185,0.000115617964,0.000024027055,0.000029214638,0.000010149461,0.00011835779,0.00006559701,0.000009501473],"category_scores_gemma":[0.00015355753,0.000053539785,0.00007756605,0.000079727724,0.000039483246,0.0000023159682,0.000028327077,0.00002745236,4.6550187e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060950824,0.00004496431,0.00003841182,0.000024002617,0.000026186312,6.903664e-7,0.00006999063,0.0008577925,0.9969113,0.0006804709,0.0002677543,0.0010175172],"study_design_scores_gemma":[0.00030829388,0.0001219328,0.000118218726,0.000014983011,0.000014581879,0.0000028486536,0.00021056067,0.0010949495,0.996741,0.00072210823,0.0005933077,0.000057247373],"about_ca_topic_score_codex":0.000013247992,"about_ca_topic_score_gemma":0.000008004928,"teacher_disagreement_score":0.1785757,"about_ca_system_score_codex":0.0000039770316,"about_ca_system_score_gemma":0.00005180672,"threshold_uncertainty_score":0.21832891},"labels":[],"label_agreement":null},{"id":"W3188121375","doi":"10.1523/jneurosci.1021-21.2021","title":"Postmitotic Prox1 Expression Controls the Final Specification of Cortical VIP Interneuron Subtypes","year":2021,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universität Zürich; York University; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Interneuron; Biology; Neuroscience; Transcription factor; Regulator; Postsynaptic potential; Inhibitory postsynaptic potential; Transcriptional regulation; Transcription (linguistics); Gene; Genetics; Receptor","score_opus":0.027811601496659188,"score_gpt":0.27105343954874833,"score_spread":0.24324183805208915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3188121375","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.982779,0.00022734632,0.016178133,0.00023244956,0.0004891259,0.00004384448,0.0000011386276,9.4985023e-7,0.00004798089],"genre_scores_gemma":[0.999003,0.0000996367,0.00039491872,0.00023421191,0.00014937486,4.6140087e-7,5.2289846e-7,0.0000046195346,0.00011324945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915636,0.00009565048,0.00028008144,0.0001261956,0.00023870057,0.00010300513],"domain_scores_gemma":[0.99931747,0.000037052192,0.00024926016,0.00014250376,0.00020719621,0.000046508692],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035204148,0.000056215882,0.000096062504,0.000022964254,0.000058932827,0.000026897816,0.00022426168,0.00003459558,0.000011522625],"category_scores_gemma":[0.0005333485,0.00003562631,0.0000782923,0.000084607345,0.00008196127,0.000007953053,0.000054410277,0.00012890727,5.391236e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000845087,0.000047971444,0.00045998467,0.0000037487189,0.0000014713208,0.000014181342,0.000022493186,0.00005180269,0.9987488,0.000098108285,0.00005468362,0.0004122405],"study_design_scores_gemma":[0.00017582634,0.00043644672,0.017009445,0.000022953385,0.0000072619546,0.0001971332,0.000054992743,0.00018443627,0.98030585,0.000054958775,0.0015144,0.000036290458],"about_ca_topic_score_codex":3.4799012e-7,"about_ca_topic_score_gemma":2.9730543e-7,"teacher_disagreement_score":0.018442951,"about_ca_system_score_codex":0.0000041838334,"about_ca_system_score_gemma":0.00008207966,"threshold_uncertainty_score":0.14527988},"labels":[],"label_agreement":null},{"id":"W3188886770","doi":"","title":"41th Symposium on Hormones and Cell Regulation (France) - The inner workings of a GPCR: Molecular basis for biased G protein activation and b-arrestin recruitment","year":2016,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"","keywords":"G protein-coupled receptor; Arrestin; Cell biology; Hormone; Receptor; Biology; Chemistry; Signal transduction; Endocrinology; Genetics","score_opus":0.0186940965877978,"score_gpt":0.23345084868233315,"score_spread":0.21475675209453535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3188886770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94594395,0.0001425654,0.051923625,0.0009676615,0.000023394508,0.000848823,0.0000047911035,0.000005436836,0.00013977425],"genre_scores_gemma":[0.99660546,0.00007248849,0.002364827,0.000105236635,0.000049980597,0.00016621032,0.000009089303,0.000013038516,0.0006137006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99943274,0.00003685832,0.00013337858,0.0002156886,0.00008004361,0.00010131736],"domain_scores_gemma":[0.9996504,0.000033303615,0.000095501826,0.00014207096,0.00005181711,0.00002691552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018291375,0.00009679973,0.00008593689,0.000025823492,0.00005685854,0.000014211322,0.000044642926,0.00008067883,0.000009679533],"category_scores_gemma":[0.00003763161,0.000053785425,0.000032819717,0.00003827813,0.000033899614,0.0000043307446,0.000024800522,0.000019586176,1.9147569e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012941376,0.000019655788,0.000049692342,0.000019900788,0.000012273507,4.353611e-8,0.000033982706,0.000012519095,0.98804045,0.0005345385,0.000082383594,0.011065125],"study_design_scores_gemma":[0.00052971626,0.00038185064,0.00020169861,0.00009060022,0.000010560814,3.0163997e-7,0.000025840867,0.000095794785,0.9945914,0.00042856505,0.003555382,0.000088271954],"about_ca_topic_score_codex":0.000011370339,"about_ca_topic_score_gemma":0.0000012129111,"teacher_disagreement_score":0.0506615,"about_ca_system_score_codex":0.0000068341087,"about_ca_system_score_gemma":0.000014599359,"threshold_uncertainty_score":0.2193306},"labels":[],"label_agreement":null},{"id":"W3189051104","doi":"10.1124/molpharm.121.000336","title":"Pharmacological Characterization of the Imipridone Anticancer Drug ONC201 Reveals a Negative Allosteric Mechanism of Action at the D2 Dopamine Receptor","year":2021,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Institute on Drug Abuse; National Health and Medical Research Council; Medical Research Council; National Institutes of Health","keywords":"Dopamine receptor D2; Allosteric regulation; Dopamine; Pharmacology; Chemistry; Antagonist; Dopamine receptor; Receptor; Biochemistry; Biology; Neuroscience","score_opus":0.01390361225199289,"score_gpt":0.2798660931300027,"score_spread":0.26596248087800983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3189051104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924821,0.00030162136,0.0040869857,0.001337864,0.001121929,0.000473506,0.00006562464,0.000007993641,0.00012232308],"genre_scores_gemma":[0.99618626,0.0006025165,0.00027253,0.0015426442,0.00019594406,0.000072914045,0.000112065856,0.000027416261,0.0009876966],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99804014,0.00067587063,0.0004024432,0.00038949694,0.00023104137,0.0002610351],"domain_scores_gemma":[0.99894035,0.000042399075,0.00040432817,0.00027495276,0.00027929648,0.000058657886],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003233627,0.00019859086,0.00029055952,0.000029163619,0.00012549081,0.0000083959585,0.00030212034,0.00014930298,0.001767342],"category_scores_gemma":[0.000060515347,0.000135926,0.00021256618,0.00019441641,0.00017545692,0.000007165313,0.0004030805,0.00016793814,0.0000064263927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022717805,0.00012639051,0.000045499666,0.00003128018,0.00024213472,0.000006336559,0.000073706375,0.000058950664,0.9978902,0.00020880223,0.00052078825,0.0005687755],"study_design_scores_gemma":[0.0008994187,0.00014193963,0.00020891115,0.000015069363,0.00017813436,0.000023689186,0.000057421053,0.00014263227,0.99502784,0.00010322554,0.003059343,0.0001423803],"about_ca_topic_score_codex":0.000008000764,"about_ca_topic_score_gemma":0.0000046791843,"teacher_disagreement_score":0.0038144558,"about_ca_system_score_codex":0.00004518008,"about_ca_system_score_gemma":0.00011242198,"threshold_uncertainty_score":0.99914515},"labels":[],"label_agreement":null},{"id":"W3191162253","doi":"10.1101/2021.08.09.455709","title":"Cell-to-cell variations in subcellular localisation of V2R are independent of its expression level","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Medical Research Council; University of Nottingham; Diabetes Canada","keywords":"Cell; Cell biology; Receptor; Endoplasmic reticulum; G protein-coupled receptor; Population; Biology; Intracellular; Mutant; Cell membrane; HEK 293 cells; Signal transduction; Biochemistry; Gene; Medicine","score_opus":0.01746220245999655,"score_gpt":0.21487602524314203,"score_spread":0.19741382278314548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3191162253","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9370019,0.0016700368,0.060161956,0.000017571929,0.00043462322,0.00049917935,0.0001945869,0.000013547199,0.000006608912],"genre_scores_gemma":[0.9915,0.00026465458,0.007921884,0.00003476429,0.0001306691,0.00006530082,0.0000062349186,0.00006674882,0.000009726377],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99776334,0.00018322277,0.0006751542,0.0007415839,0.00035657696,0.00028010682],"domain_scores_gemma":[0.99778026,0.000017958437,0.00063259905,0.00080871047,0.00062237616,0.00013808241],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004914962,0.00032820582,0.00047124733,0.00021734212,0.00004406215,0.00004021554,0.00038309384,0.00066576933,0.00006481767],"category_scores_gemma":[0.00014040455,0.00037569154,0.00015819426,0.0002882316,0.000024602497,0.000009646232,0.00049603794,0.00030636913,0.0000035850173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032949865,0.00026797137,0.0023248454,0.00051794236,0.0000269933,0.000009306365,0.0000269865,0.0027552347,0.99394894,0.000044668875,0.000043648637,5.0889224e-7],"study_design_scores_gemma":[0.00048104618,0.0000664831,0.007613785,0.0004649171,0.000034640165,5.6915868e-9,0.000030716306,0.000303404,0.990504,8.518135e-7,0.00014829195,0.00035183234],"about_ca_topic_score_codex":0.000050741342,"about_ca_topic_score_gemma":0.000006856182,"teacher_disagreement_score":0.05449813,"about_ca_system_score_codex":0.000057720692,"about_ca_system_score_gemma":0.0004760959,"threshold_uncertainty_score":0.9998695},"labels":[],"label_agreement":null},{"id":"W3191668754","doi":"10.1124/molpharm.121.000294","title":"β2-Adrenoceptor Agonists Promote Extracellular Signal-Regulated Kinase 1/2 Dephosphorylation in Human Airway Epithelial Cells by Canonical, cAMP-Driven Signaling Independently of β-Arrestin 2","year":2021,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Formoterol; Kinase; Cell biology; Biology; Phosphorylation; MAPK/ERK pathway; Protein kinase A; Signal transduction; Formoterol Fumarate; Beta adrenergic receptor kinase; Dephosphorylation; Endocrinology; Internal medicine; G protein-coupled receptor; Medicine; Phosphatase","score_opus":0.006845915366163545,"score_gpt":0.25187477028322425,"score_spread":0.2450288549170607,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3191668754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9864591,0.0029739526,0.009443437,0.000075369164,0.00039249085,0.00050312065,0.00007520032,0.000023621584,0.00005374319],"genre_scores_gemma":[0.9973249,0.00007947916,0.0011279336,0.00018507634,0.00014042675,0.00005693313,0.0006326638,0.00008211529,0.00037049752],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99688524,0.00052636553,0.0007745671,0.00086385175,0.00033914836,0.0006108359],"domain_scores_gemma":[0.9988364,0.000027996688,0.0003357303,0.0003388958,0.00025265873,0.00020830112],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004271726,0.00038858224,0.00049584603,0.00011879133,0.00013308377,0.000036311754,0.0003575345,0.00050466834,0.0023057053],"category_scores_gemma":[0.00003299858,0.0004490654,0.00022791774,0.00030721008,0.00013814314,0.0000112427915,0.0002054798,0.0003729382,0.00001019284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013619664,0.00040514703,0.0001535406,0.000051662482,0.00015102686,0.00030204866,0.0001103289,0.007721266,0.98982984,0.000046338246,0.0004303661,0.00066222966],"study_design_scores_gemma":[0.0021950605,0.0003670039,0.000021031172,0.000034866516,0.00009881082,0.000017734676,0.000046929752,0.0010055151,0.9920639,0.000078533005,0.003625962,0.0004446966],"about_ca_topic_score_codex":0.00013194681,"about_ca_topic_score_gemma":0.00004372682,"teacher_disagreement_score":0.010865809,"about_ca_system_score_codex":0.000081755876,"about_ca_system_score_gemma":0.00036823459,"threshold_uncertainty_score":0.9997961},"labels":[],"label_agreement":null},{"id":"W3193064191","doi":"10.1016/j.bbagen.2021.129969","title":"Identification of the interactome of the DP1 receptor for Prostaglandin D2: Regulation of DP1 receptor signaling and trafficking by IQGAP1","year":2021,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Centre Hospitalier Universitaire de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"IQGAP1; Cell biology; Scaffold protein; G protein-coupled receptor; Internalization; Gene knockdown; Interactome; Signal transduction; Receptor; Biology; Chemistry; Cell culture; Biochemistry","score_opus":0.008242054466198863,"score_gpt":0.23407946088919127,"score_spread":0.2258374064229924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3193064191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99772745,0.0002678522,0.00040032945,0.00038974255,0.00040965618,0.00052412564,0.00025990733,0.000007486256,0.000013472162],"genre_scores_gemma":[0.99813217,0.00011721025,0.0007570552,0.000068245674,0.00019048603,0.000031718522,0.00029571273,0.000036337595,0.00037108408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982997,0.00020604079,0.00058761815,0.00043672067,0.00025665402,0.00021323607],"domain_scores_gemma":[0.9984425,0.000052436237,0.0007189317,0.0004632231,0.0002762989,0.00004661585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032376955,0.00021779945,0.0003009427,0.000039690705,0.00012445803,0.00003670497,0.0003056851,0.00018177436,0.000018320261],"category_scores_gemma":[0.0001548143,0.00015690114,0.00027496312,0.00026803848,0.00013653655,0.000018467186,0.0001624738,0.00010533193,3.2698014e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014502244,0.00010749598,0.000037456077,0.00012162221,0.00009129573,2.2647011e-8,0.00042844994,0.00004827849,0.99785924,0.00016425783,0.00061435904,0.00038252983],"study_design_scores_gemma":[0.000490645,0.00015729698,0.0006032889,0.00012538016,0.000057727728,0.0000017809501,0.00014630021,0.00030886635,0.9974799,0.00010508952,0.00034383486,0.00017989645],"about_ca_topic_score_codex":0.000017381823,"about_ca_topic_score_gemma":0.0000071463373,"teacher_disagreement_score":0.0005658328,"about_ca_system_score_codex":0.00002131767,"about_ca_system_score_gemma":0.00012341607,"threshold_uncertainty_score":0.6398243},"labels":[],"label_agreement":null},{"id":"W3193588325","doi":"10.1038/s41422-021-00552-3","title":"Structural insights into ligand recognition and activation of the melanocortin-4 receptor","year":2021,"lang":"en","type":"article","venue":"Cell Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Key New Drug Creation and Manufacturing Program, Ministry of Science and Technology; Zhejiang University; Novo Nordisk; National Natural Science Foundation of China","keywords":"Melanocortin 4 receptor; Biology; Heterotrimeric G protein; Melanocortin 3 receptor; Agonist; Receptor; Functional selectivity; Melanocortin; G protein-coupled receptor; Melanocortin receptor; Ligand (biochemistry); Cell biology; G protein; Biochemistry","score_opus":0.04678645002691675,"score_gpt":0.3019139073268521,"score_spread":0.25512745729993536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3193588325","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99821854,0.0006443724,0.00007151558,0.000075477714,0.00007725746,0.000104376304,0.0000019420947,0.0000016342619,0.0008049134],"genre_scores_gemma":[0.9985018,0.00032122078,0.00030421797,0.00002138574,0.000102412974,0.0000069076928,0.00005751715,0.000007935591,0.0006765974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992584,0.00014738897,0.0001086206,0.00018518078,0.00018468463,0.00011572013],"domain_scores_gemma":[0.99944913,0.000026580505,0.000038071677,0.00016499545,0.0002842271,0.00003696407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002011773,0.00005136735,0.000060624105,0.000026102936,0.00013056173,0.000022436136,0.000081826925,0.0000887215,0.000085878535],"category_scores_gemma":[0.00013750407,0.000037057805,0.00003089192,0.00013535481,0.00006507113,0.000003844678,0.00013775908,0.00012110876,0.0000038217568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002401009,0.000008758283,0.00017075661,0.000028202583,0.000006401836,2.5755077e-7,0.00020409911,0.0000023626615,0.99131167,0.00002683673,0.00021102495,0.008005617],"study_design_scores_gemma":[0.00016670978,0.00007539426,0.0003175178,0.000021716356,0.0000020376567,0.0000010649107,0.0003113869,0.000029538944,0.9940529,0.0017016319,0.0032724827,0.00004764969],"about_ca_topic_score_codex":0.000022826045,"about_ca_topic_score_gemma":0.000012479717,"teacher_disagreement_score":0.007957968,"about_ca_system_score_codex":0.000009173036,"about_ca_system_score_gemma":0.00008671339,"threshold_uncertainty_score":0.15111734},"labels":[],"label_agreement":null},{"id":"W3195231970","doi":"10.1016/j.jmb.2021.167202","title":"Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G","year":2021,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Ligand (biochemistry); Chemistry; Protein kinase A; Substituent; cGMP-dependent protein kinase; Selectivity; Stereochemistry; Protein dynamics; Conformational change; Protein structure; Receptor; Biophysics; Kinase; Biochemistry; Cyclin-dependent kinase 2; Biology","score_opus":0.005628521241147122,"score_gpt":0.2460130384225142,"score_spread":0.24038451718136708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195231970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9565525,0.00046781948,0.042322457,0.00024199649,0.00011595282,0.0001895327,0.000005799066,0.000004064812,0.00009989099],"genre_scores_gemma":[0.9935008,0.0000339322,0.0059607364,0.00016252023,0.00017635652,0.0000149103125,0.00004111974,0.000016155343,0.00009346056],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985443,0.00030478826,0.00045880812,0.00023466497,0.00015398409,0.00030347097],"domain_scores_gemma":[0.99902123,0.000010836656,0.00034746077,0.00012067838,0.00039906974,0.00010071139],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005690959,0.00016573053,0.00028982936,0.00012581356,0.000058381935,0.000028560195,0.00013883869,0.00021643424,0.00004946647],"category_scores_gemma":[0.00032036615,0.00015267206,0.00015358564,0.00020396996,0.00006877108,0.000012476508,0.000063010884,0.0002806013,0.0000038849803],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023292261,0.00010486497,0.0010431873,0.000014441251,0.00007352479,0.000052975964,0.00004167072,0.00017092987,0.995517,0.0009000987,0.00003728862,0.0018110693],"study_design_scores_gemma":[0.00090951263,0.0010094026,0.0004244492,0.000040257557,0.000011276946,0.00030166557,0.00005654734,0.00011545678,0.9927822,0.0010002864,0.0031791104,0.00016988273],"about_ca_topic_score_codex":0.000010388806,"about_ca_topic_score_gemma":0.000039759565,"teacher_disagreement_score":0.03694832,"about_ca_system_score_codex":0.00004896485,"about_ca_system_score_gemma":0.00046329253,"threshold_uncertainty_score":0.62257856},"labels":[],"label_agreement":null},{"id":"W3195509796","doi":"10.1021/acs.jcim.1c00856","title":"Toward Reducing hERG Affinities for DAT Inhibitors with a Combined Machine Learning and Molecular Modeling Approach","year":2021,"lang":"en","type":"article","venue":"Journal of Chemical Information and Modeling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health; University of Calgary","keywords":"hERG; Quantitative structure–activity relationship; Dopamine transporter; Pharmacology; Computational biology; Chemistry; Dopamine; Potassium channel; Medicine; Dopaminergic; Neuroscience; Biology; Stereochemistry; Internal medicine","score_opus":0.019378590927521016,"score_gpt":0.23452885474007643,"score_spread":0.21515026381255542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3195509796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5809139,0.0007217435,0.41816264,0.00006574435,0.000023328259,0.00004226779,0.000001666088,0.000003124549,0.000065591084],"genre_scores_gemma":[0.9618378,0.00034623136,0.037509497,0.00013056627,0.000074078715,0.000003532906,0.00008213717,0.0000103649945,0.000005740054],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.999253,0.000016386131,0.0003812013,0.0000947559,0.00013080607,0.00012388019],"domain_scores_gemma":[0.9994052,0.0000087324715,0.00015496956,0.000047656373,0.0002992104,0.00008422848],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025278598,0.000109591216,0.00017594096,0.00004730519,0.00006243219,0.0000907206,0.000043183518,0.000092281225,0.000002231544],"category_scores_gemma":[0.00008669136,0.000090484566,0.00005898948,0.000038625225,0.000015445263,0.00005215737,0.00004943626,0.00015542092,4.2624617e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028895424,0.0000197151,0.00000962951,0.00013940557,0.0000699438,0.0000017932941,0.0006864462,0.22971794,0.76653415,0.00019322778,0.00001033005,0.00232847],"study_design_scores_gemma":[0.000791972,0.00011370939,1.3803444e-8,0.00006165457,0.000024139374,0.00012969717,0.0012248778,0.6807591,0.3164822,0.00010524091,0.00021151993,0.00009589623],"about_ca_topic_score_codex":0.000002879135,"about_ca_topic_score_gemma":1.0786525e-7,"teacher_disagreement_score":0.45104116,"about_ca_system_score_codex":0.000009002872,"about_ca_system_score_gemma":0.00006505042,"threshold_uncertainty_score":0.36898533},"labels":[],"label_agreement":null},{"id":"W3196408047","doi":"10.21203/rs.3.rs-870555/v1","title":"The pocketome of G protein-coupled receptors reveals previously untargeted allosteric sites","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Allosteric regulation; Receptor; Chemistry; G protein-coupled receptor; Cell biology; Biology; Biochemistry","score_opus":0.03846688294217985,"score_gpt":0.34542486251738275,"score_spread":0.3069579795752029,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3196408047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809437,0.016167529,0.00021057272,0.00022851287,0.00026751906,0.0019092913,0.000038555994,0.00001839031,0.00021596023],"genre_scores_gemma":[0.9903119,0.0038726048,0.0010929238,0.000020845602,0.00039247,0.0004806903,0.00090198015,0.00007925182,0.0028473095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99570715,0.0010600679,0.000606821,0.0008498585,0.00097516616,0.0008009304],"domain_scores_gemma":[0.9967765,0.00012378594,0.00027608208,0.0012915747,0.0013416957,0.00019034791],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0028796482,0.00033450042,0.00046467758,0.000130147,0.0003317426,0.0002256861,0.00092388486,0.00059527985,0.00038061562],"category_scores_gemma":[0.0012033777,0.00025319375,0.0003239019,0.00034355037,0.00020709622,0.0000046502546,0.0019502096,0.000897989,0.000011583146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014334447,0.000073636314,0.00041073438,0.00075526786,0.00019212085,0.000008334823,0.000190158,0.00005506167,0.99566734,0.000044918164,0.0008925625,0.0015665455],"study_design_scores_gemma":[0.0003694362,0.00094354764,0.0003344255,0.0011087403,0.000025048177,0.000005994517,0.0011150254,0.00017370304,0.9868284,0.00074786297,0.007897171,0.0004506524],"about_ca_topic_score_codex":0.00013027198,"about_ca_topic_score_gemma":0.00007811354,"teacher_disagreement_score":0.012294924,"about_ca_system_score_codex":0.00007892427,"about_ca_system_score_gemma":0.0006495745,"threshold_uncertainty_score":0.999992},"labels":[],"label_agreement":null},{"id":"W3197717323","doi":"10.1021/acsptsci.1c00157","title":"Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants","year":2021,"lang":"en","type":"article","venue":"ACS Pharmacology & Translational Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; Fonds de Recherche du Québec - Santé; China Scholarship Council; Institut National de la Santé et de la Recherche Médicale; National Institutes of Health; Canada Research Chairs; Wellcome Trust; Agence Nationale de la Recherche; Université de Montréal; Diabetes UK; Diabetes Canada; Centre National de la Recherche Scientifique; Canadian Institutes of Health Research; Wellcome","keywords":"Identification (biology); Melatonin receptor; Key (lock); Melatonin; Computational biology; Receptor; Biology; Neuroscience; Genetics; Ecology","score_opus":0.013838769076555976,"score_gpt":0.29267901704797755,"score_spread":0.2788402479714216,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3197717323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920708,0.0006151705,0.005644362,0.0005482739,0.00081849913,0.000117396885,0.00003791606,0.0000107889655,0.00013677911],"genre_scores_gemma":[0.9979368,0.000057836845,0.00095129164,0.00017326298,0.00017987734,0.000011855741,0.0003155535,0.00000859971,0.00036495592],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986016,0.000115786555,0.00029792634,0.0004332191,0.00033383642,0.00021760422],"domain_scores_gemma":[0.9990905,0.000047043206,0.00015629831,0.000114094015,0.0005211741,0.00007087403],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007057537,0.00010460798,0.00011883145,0.000053718915,0.00037737997,0.000019372825,0.00019594071,0.000095615185,0.00031579047],"category_scores_gemma":[0.00010007871,0.00011017171,0.000051884275,0.00051710743,0.00023646913,0.000032100546,0.00003730525,0.00014104931,0.0000054491074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032189368,0.00006768507,0.0009701011,0.0000053561957,0.00003572334,5.4152775e-7,0.0000666441,0.00022171068,0.9957001,0.0011494798,0.0015238513,0.00022660874],"study_design_scores_gemma":[0.00039117638,0.000045781762,0.0054188957,0.000003977988,0.000027019085,0.000010218119,0.000018632438,0.0004815741,0.9922685,0.00038818072,0.0008318855,0.00011413367],"about_ca_topic_score_codex":0.0000051492875,"about_ca_topic_score_gemma":0.000005768665,"teacher_disagreement_score":0.005865953,"about_ca_system_score_codex":0.000024060833,"about_ca_system_score_gemma":0.00043817874,"threshold_uncertainty_score":0.4492672},"labels":[],"label_agreement":null},{"id":"W3198128840","doi":"10.1016/j.jsbmb.2021.105995","title":"Loss of β-Arrestins or six Gα proteins in HEK293 cells caused Warburg effect and prevented progesterone-induced rapid proteasomal degradation of progesterone receptor membrane component 1","year":2021,"lang":"en","type":"article","venue":"The Journal of Steroid Biochemistry and Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Progesterone receptor; HEK 293 cells; Biology; Cell biology; Glycolysis; Receptor; Signal transduction; Chemistry; Biochemistry; Metabolism; Estrogen receptor","score_opus":0.009739869023862594,"score_gpt":0.24910649247791175,"score_spread":0.23936662345404916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198128840","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960294,0.0021779211,0.0008797009,0.00016650134,0.000086855725,0.0006254292,0.00002638441,0.0000029785258,0.000004839553],"genre_scores_gemma":[0.9979999,0.00048323232,0.0012791343,0.000032925993,0.000059244903,0.000022063314,0.00006018101,0.00002141854,0.000041898016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980389,0.0005430645,0.0007073121,0.00029560542,0.00016566197,0.00024946567],"domain_scores_gemma":[0.9986899,0.000055347355,0.0006570599,0.00028538093,0.00020866707,0.00010366046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079983345,0.00026079794,0.00052999577,0.00005575258,0.000048263963,0.000012636917,0.00021159556,0.00027872133,0.000014389333],"category_scores_gemma":[0.00015100426,0.00017704039,0.000098089644,0.00012595742,0.00020712685,0.000009768749,0.00016343073,0.00023007866,1.2944768e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014602679,0.00019705287,0.0007480616,0.00043249523,0.0001689181,0.00003096811,0.000088650064,0.00001003055,0.99532145,0.0000041291905,0.000004439058,0.0015335401],"study_design_scores_gemma":[0.00222254,0.0026313753,0.00018331263,0.00033797024,0.00008324961,0.0003396232,0.00013232545,0.000018215636,0.9938004,0.0000109446855,0.00006553414,0.0001745101],"about_ca_topic_score_codex":0.000010984787,"about_ca_topic_score_gemma":0.00000648413,"teacher_disagreement_score":0.0024343224,"about_ca_system_score_codex":0.00001662083,"about_ca_system_score_gemma":0.00016897681,"threshold_uncertainty_score":0.72194976},"labels":[],"label_agreement":null},{"id":"W3198246574","doi":"10.1016/j.pharmthera.2021.107977","title":"G protein-coupled receptor-effector macromolecular membrane assemblies (GEMMAs)","year":2021,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; Fundación Dr. Antoni Esteve; National Institute of General Medical Sciences; National Institute of Mental Health; Centre National de la Recherche Scientifique; Universitat de Barcelona; National Institute on Drug Abuse; Agencia Estatal de Investigación; Ministerio de Ciencia, Innovación y Universidades; Agence Nationale de la Recherche; Institut National de la Santé et de la Recherche Médicale","keywords":"G protein-coupled receptor; Effector; Heterotrimeric G protein; Cell biology; Biology; Receptor; Rhodopsin-like receptors; G protein; Cell signaling; Signal transduction; Chemistry; Biochemistry; Agonist","score_opus":0.047112551343446524,"score_gpt":0.34941911501873985,"score_spread":0.3023065636752933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198246574","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001184529,0.9936483,0.0010889118,0.00007618133,0.0018551048,0.00181539,0.0001086166,0.00007008646,0.00015288524],"genre_scores_gemma":[0.00014056967,0.9921296,0.0010455983,0.001130286,0.0013985274,0.00076499954,0.0016950368,0.00026657985,0.0014287787],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9958556,0.001018824,0.00081117573,0.0011697178,0.0003257743,0.00081890554],"domain_scores_gemma":[0.9982804,0.000083820276,0.0005184689,0.0006807494,0.00023167432,0.00020489539],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00056144455,0.0009844336,0.0019059367,0.00016100312,0.00021879171,0.00009927056,0.00080100534,0.0011969223,0.0017349594],"category_scores_gemma":[0.000016367841,0.00088713143,0.0011045395,0.0003517362,0.00014331238,0.000006728815,0.00036072897,0.00077015936,0.00018515607],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036715537,0.00017533118,3.3096777e-7,0.002434526,0.0032559927,0.00005815363,0.000019125846,0.000004895933,0.8575451,0.00004373723,0.0011334387,0.13529266],"study_design_scores_gemma":[0.00045710374,0.00022273907,2.4500538e-8,0.00070682075,0.0021787244,0.000061338586,0.000009483405,0.000020669688,0.2547461,0.000005466753,0.7409263,0.00066522515],"about_ca_topic_score_codex":0.0000056768104,"about_ca_topic_score_gemma":0.0000020490188,"teacher_disagreement_score":0.7397929,"about_ca_system_score_codex":0.00008677871,"about_ca_system_score_gemma":0.0006155821,"threshold_uncertainty_score":0.99935794},"labels":[],"label_agreement":null},{"id":"W3198325475","doi":"10.1038/s42003-021-02574-4","title":"Bivalent ligands promote endosomal trafficking of the dopamine D3 receptor-neurotensin receptor 1 heterodimer","year":2021,"lang":"en","type":"article","venue":"Communications Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft; Canada Research Chairs; Government of Canada","keywords":"Bivalent (engine); Endosome; Dopamine receptor D3; Chemistry; Receptor; Cell biology; Dopamine receptor D1; Dopamine receptor D2; Biology; Biochemistry","score_opus":0.025350917102715153,"score_gpt":0.27244181474458085,"score_spread":0.2470908976418657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198325475","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902131,0.0040897964,0.0009688384,0.0033930729,0.00051830726,0.00023017601,0.00007501166,0.000019998573,0.00049168774],"genre_scores_gemma":[0.9930211,0.0014776496,0.0042381594,0.00019656913,0.00011431704,0.0000292112,0.00023379533,0.00002356404,0.00066568993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869746,0.00033988594,0.00035528737,0.00031260384,0.00007260718,0.00022215166],"domain_scores_gemma":[0.9977427,0.000055422493,0.00018180875,0.0017634573,0.00020849332,0.00004809109],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021496198,0.00015267966,0.00020157812,0.000033454435,0.00021981222,0.000011857801,0.0008022094,0.00018595072,0.00015434145],"category_scores_gemma":[0.00021935164,0.00010921784,0.00017595776,0.00018795991,0.00027092185,0.000003608788,0.0007331953,0.00016025035,0.000012941459],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016065707,0.000082765655,0.0006699876,0.0000063736115,0.000050481292,1.617107e-7,0.000041094496,0.0000050158833,0.9918945,0.00096979836,0.0003533648,0.005910393],"study_design_scores_gemma":[0.00028009122,0.00011713661,0.00013584625,0.000029496485,0.000013948997,0.000014966105,0.000040633287,0.000029733645,0.85417134,0.00007962938,0.14497127,0.00011592412],"about_ca_topic_score_codex":0.000004328173,"about_ca_topic_score_gemma":0.0000147074015,"teacher_disagreement_score":0.1446179,"about_ca_system_score_codex":0.00001384462,"about_ca_system_score_gemma":0.000097397555,"threshold_uncertainty_score":0.44537744},"labels":[],"label_agreement":null},{"id":"W3198549222","doi":"10.1016/j.vascn.2021.107118","title":"A calcium fluorescence assay for quantification of cholinergic receptor activity of clinical drugs in serum - comparison with radioactive methods","year":2021,"lang":"en","type":"article","venue":"Journal of Pharmacological and Toxicological Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Dementia Research Alliance; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Agonist; Cholinergic; Carbachol; Receptor; Chemistry; Partial agonist; Pharmacology; Antagonist; Internal medicine; Endocrinology; Biology; Biochemistry; Medicine","score_opus":0.1374465336897217,"score_gpt":0.5015687606815049,"score_spread":0.3641222269917832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198549222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6455773,0.00058669917,0.35318473,0.00018036072,0.00025046477,0.00017681428,0.000012444634,0.0000021205653,0.000029036217],"genre_scores_gemma":[0.5706454,0.00032973988,0.42880952,0.000051148854,0.00012571369,0.000010270986,0.0000026389291,0.000005751941,0.000019812836],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9946995,0.0034101666,0.0011128605,0.00036515237,0.00018176819,0.00023056344],"domain_scores_gemma":[0.99657154,0.0015965315,0.0010641724,0.000113493305,0.00047985467,0.00017440938],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0071597975,0.00018418801,0.0010046086,0.000062814994,0.00004499278,0.000011950849,0.00020187617,0.00038713898,0.00011714558],"category_scores_gemma":[0.0019934129,0.00011689192,0.00029524433,0.00022214842,0.00024549014,0.000015408183,0.00009880918,0.00046325015,8.382478e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0024970423,0.001022434,0.0023977924,0.000037208505,0.00016914315,0.000003898227,0.000040910738,0.00022515519,0.87041646,0.00016410228,0.000040041185,0.122985825],"study_design_scores_gemma":[0.0020842066,0.0033593422,0.008222365,0.000032866577,0.00014297191,0.00002176795,0.00017554848,0.0028049832,0.9817799,0.0003562574,0.0008733474,0.00014645449],"about_ca_topic_score_codex":0.0000018052675,"about_ca_topic_score_gemma":7.428426e-7,"teacher_disagreement_score":0.12283937,"about_ca_system_score_codex":0.000019353616,"about_ca_system_score_gemma":0.00015824856,"threshold_uncertainty_score":0.4766714},"labels":[],"label_agreement":null},{"id":"W3198675063","doi":"10.1101/2021.09.07.459250","title":"Common coupling map advances GPCR-G protein selectivity","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Lundbeckfonden; H. Lundbeck A/S; Novo Nordisk Fonden; Novo Nordisk; Japan Agency for Medical Research and Development","keywords":"G protein-coupled receptor; Computational biology; G protein; Functional selectivity; Receptor; Drug discovery; Signal transduction; Biology; Bioinformatics; Chemistry; Cell biology; Biochemistry","score_opus":0.008635264668964396,"score_gpt":0.22074908552596242,"score_spread":0.21211382085699804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198675063","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762028,0.009585436,0.012075504,0.00006528174,0.0011010007,0.0007432586,0.00008047483,0.00013708565,0.000009157037],"genre_scores_gemma":[0.98972017,0.00053430593,0.008319764,0.00010975516,0.00089863746,0.00023683025,0.000004271371,0.00015587852,0.000020395162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970015,0.00013325953,0.0004930697,0.0013754141,0.00037009042,0.00062662194],"domain_scores_gemma":[0.99762094,0.000016530428,0.0004094497,0.0012199774,0.0004938061,0.00023931311],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005676585,0.0006263865,0.00062197365,0.00010035931,0.00023808547,0.00028498846,0.00055349455,0.0008337015,0.00008076547],"category_scores_gemma":[0.00013599983,0.00070353027,0.00026904774,0.00022182816,0.00008232744,0.000018638704,0.00074219384,0.00074734347,0.000015759777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037834332,0.000116232455,0.0015308623,0.0003777693,0.00013943277,0.00002817278,0.0000031519542,0.0006668232,0.9969136,0.000106262014,0.000075374825,0.0000044924045],"study_design_scores_gemma":[0.0003035067,0.000100877165,0.0009825914,0.00039348123,0.000053750056,2.5411952e-8,0.0000062281997,0.00053935195,0.9874052,0.0000032352343,0.009391104,0.00082064647],"about_ca_topic_score_codex":0.000041235744,"about_ca_topic_score_gemma":0.000017489443,"teacher_disagreement_score":0.013517362,"about_ca_system_score_codex":0.000086808504,"about_ca_system_score_gemma":0.00063101086,"threshold_uncertainty_score":0.9995416},"labels":[],"label_agreement":null},{"id":"W3199643757","doi":"10.1101/2021.09.13.460151","title":"Allosteric modulation of the adenosine A <sub>2A</sub> receptor by cholesterol","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Japan Science and Technology Agency; Core Research for Evolutional Science and Technology; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Allosteric regulation; Cholesterol; Chemistry; Phospholipid; Biophysics; GTP'; Allosteric enzyme; Membrane fluidity; Membrane; Cell membrane; Biochemistry; Receptor; Enzyme; Biology","score_opus":0.00738565205058666,"score_gpt":0.19359523645484608,"score_spread":0.18620958440425942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199643757","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99173653,0.002001394,0.0041531296,0.0001353921,0.0011840047,0.00053858146,0.0002104141,0.000037956317,0.0000025945676],"genre_scores_gemma":[0.9974653,0.00055852544,0.0011102733,0.00022483032,0.00041802172,0.0000872438,0.0000082125125,0.00011731904,0.000010255025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99756646,0.00021490683,0.0005601045,0.0009083051,0.0003727672,0.00037746324],"domain_scores_gemma":[0.99751467,0.000011326778,0.0005653084,0.0013164299,0.0004531823,0.00013907423],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003146019,0.000466838,0.0004493742,0.000066625194,0.00011647175,0.00012901395,0.00060087885,0.0007113798,0.000040781786],"category_scores_gemma":[0.00012461575,0.00043031166,0.00029151738,0.00026181655,0.00008991,0.000011976228,0.0007435517,0.0004133842,0.0000063336242],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002429179,0.000098626384,0.0009736687,0.00016581388,0.00013854729,0.0000011502049,0.0000071334584,0.00017899265,0.9976563,0.0000115510165,0.0007355726,0.000008344821],"study_design_scores_gemma":[0.0003569054,0.00006818478,0.007074126,0.0002977054,0.00006483859,2.4376567e-8,0.000004182701,0.00016527665,0.9896962,4.2711864e-7,0.0018318109,0.00044032594],"about_ca_topic_score_codex":0.000018152894,"about_ca_topic_score_gemma":0.0000026164944,"teacher_disagreement_score":0.007960116,"about_ca_system_score_codex":0.000057945137,"about_ca_system_score_gemma":0.000331509,"threshold_uncertainty_score":0.99981487},"labels":[],"label_agreement":null},{"id":"W3199752858","doi":"10.1101/2021.09.14.460253","title":"Dissecting the allosteric networks governing agonist efficacy and potency in G protein-coupled receptors","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Medical Research Council; National Institutes of Health; European Commission; American Lebanese Syrian Associated Charities; American Heart Association","keywords":"Allosteric regulation; G protein-coupled receptor; Agonist; Receptor; Potency; Chemistry; Intrinsic activity; Ligand (biochemistry); Allosteric modulator; Pharmacology; Extracellular; Biophysics; Biochemistry; Biology; In vitro","score_opus":0.007860965179788128,"score_gpt":0.20494170240914622,"score_spread":0.1970807372293581,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199752858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98866266,0.0049832617,0.004044589,0.00008459986,0.0013051229,0.0008460737,0.000012595801,0.000052310046,0.000008767806],"genre_scores_gemma":[0.99637365,0.00058182405,0.0017935965,0.00010138989,0.00082799635,0.00016394471,0.0000033071549,0.00012899822,0.000025313258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972414,0.0002040729,0.00054432324,0.0011536458,0.00026159617,0.0005949724],"domain_scores_gemma":[0.9982329,0.000037848775,0.0004003415,0.0009048294,0.0002583388,0.00016576846],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00075956166,0.00054512784,0.00047002203,0.00007107392,0.0002825981,0.00042162137,0.00047707363,0.00065629004,0.00004080368],"category_scores_gemma":[0.00042093234,0.00049270457,0.00014673258,0.00030273158,0.00009869825,0.000012366275,0.0009152811,0.000874001,0.0000026597413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004956616,0.00006251275,0.0018058624,0.00012666221,0.00008973822,0.000026051122,0.00001900699,0.001081229,0.9966697,0.00004338165,0.000013228796,0.000013069879],"study_design_scores_gemma":[0.0013945163,0.00024233265,0.023513075,0.0012519613,0.00013394315,1.7886414e-7,0.00010825525,0.006495553,0.96198213,0.0000016947579,0.003089407,0.001786949],"about_ca_topic_score_codex":0.0001353024,"about_ca_topic_score_gemma":0.000028722117,"teacher_disagreement_score":0.034687556,"about_ca_system_score_codex":0.0000730633,"about_ca_system_score_gemma":0.000273196,"threshold_uncertainty_score":0.99975246},"labels":[],"label_agreement":null},{"id":"W3199782511","doi":"10.1101/2021.09.23.461493","title":"Computationally designed GPCR quaternary structures bias signaling pathway activation","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; Université de Montréal; Fondation pour la Recherche Médicale; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Fonds National de la Recherche Luxembourg; École Polytechnique Fédérale de Lausanne; Fonds Wetenschappelijk Onderzoek; Ludwig Institute for Cancer Research; National Science Foundation","keywords":"Protein quaternary structure; G protein-coupled receptor; Receptor; Signal transduction; Cell biology; Chemokine receptor; Biology; Chemistry; Biophysics; Chemokine; Biochemistry","score_opus":0.020030898696611073,"score_gpt":0.22503405783382022,"score_spread":0.20500315913720915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3199782511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8942613,0.00078616006,0.103530616,0.000050991068,0.00078481477,0.00040864793,0.000073912975,0.00009924282,0.0000043231003],"genre_scores_gemma":[0.97127515,0.00008344621,0.027085967,0.00031574836,0.0009936403,0.00007195372,0.000020232683,0.00014565533,0.000008220315],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997012,0.00029055978,0.00059153046,0.001178073,0.0004670187,0.00046080578],"domain_scores_gemma":[0.99772435,0.0000468338,0.00052642537,0.00079410104,0.00070124434,0.00020701795],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047599207,0.000591553,0.00047613258,0.00015732567,0.00021829102,0.00037608884,0.0004829777,0.000783001,0.00012585598],"category_scores_gemma":[0.00021646978,0.0006454581,0.00026528304,0.00020625118,0.000060070688,0.000018694762,0.0004579289,0.00047150595,0.000008267292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005080888,0.000063729116,0.0007820884,0.00014683706,0.00023310227,0.000025993393,0.000013536474,0.0056293933,0.9926909,0.00028579432,0.000071063856,0.0000067468372],"study_design_scores_gemma":[0.0003884901,0.00008645985,0.0036640062,0.00023236667,0.000046309713,5.054494e-8,0.000012520043,0.00066828955,0.9935124,0.0000120543855,0.0006420174,0.00073502184],"about_ca_topic_score_codex":0.000038925562,"about_ca_topic_score_gemma":0.0000016476029,"teacher_disagreement_score":0.07701384,"about_ca_system_score_codex":0.000081469865,"about_ca_system_score_gemma":0.00092198636,"threshold_uncertainty_score":0.9995997},"labels":[],"label_agreement":null},{"id":"W3200535268","doi":"10.1111/ejn.15454","title":"Abnormal dendritic morphology in the cerebellum of cyclooxygenase‐2 <sup>−</sup> knockin mice","year":2021,"lang":"en","type":"article","venue":"European Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Dendritic spine; Cerebellum; Autism; Biology; Cell biology; Soma; Neuroscience; Psychology; Hippocampal formation","score_opus":0.015798714877213526,"score_gpt":0.2350725994442496,"score_spread":0.2192738845670361,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3200535268","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960928,0.0005123142,0.0021312071,0.00021084707,0.00028646085,0.000038839353,0.000004200815,0.0000013956002,0.00072192046],"genre_scores_gemma":[0.9978704,0.00021914749,0.0006628751,0.0009283217,0.00018272772,3.3109214e-7,0.0000013464679,0.000013485372,0.00012138414],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981089,0.00076486013,0.00043564022,0.00021581032,0.0002459442,0.00022881855],"domain_scores_gemma":[0.9993166,0.00003190881,0.00022141305,0.00022939692,0.00013401023,0.000066671135],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010783843,0.000106390165,0.00015168625,0.00006210196,0.00006542908,0.00003377928,0.00061297783,0.000026442274,0.000024817995],"category_scores_gemma":[0.0003414671,0.00007997641,0.00011345594,0.00023709924,0.00012719801,0.000011720115,0.0001208486,0.00021550283,0.0000035031253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021534703,0.00007095639,0.00023252837,0.000006424245,0.0000027718504,0.00078109564,0.00019423876,0.0024269694,0.99546885,0.00004859154,0.00020867969,0.00053734175],"study_design_scores_gemma":[0.0010071397,0.0012326972,0.020050695,0.00006927576,0.000022567214,0.005837188,0.0010321167,0.00068083033,0.9531604,0.000043311717,0.016640106,0.00022367029],"about_ca_topic_score_codex":0.0000016833858,"about_ca_topic_score_gemma":0.000001149205,"teacher_disagreement_score":0.042308465,"about_ca_system_score_codex":0.0000049510836,"about_ca_system_score_gemma":0.00009859417,"threshold_uncertainty_score":0.32613432},"labels":[],"label_agreement":null},{"id":"W3200830448","doi":"10.1016/j.nucmedbio.2021.09.001","title":"Novel O-[11C]-methylated derivatives of the neprilysin inhibitor sacubitril: Radiosynthesis, autoradiography and plasma stability evaluation","year":2021,"lang":"en","type":"article","venue":"Nuclear Medicine and Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Chemistry; Thiorphan; Neprilysin; Sacubitril; High-performance liquid chromatography; Metabolite; Radiosynthesis; In vivo; Chromatography; Biochemistry; Enzyme; Biology","score_opus":0.03997010860827155,"score_gpt":0.2778086136440414,"score_spread":0.23783850503576986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3200830448","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995555,0.0029219761,0.00023424417,0.0008077271,0.00017543999,0.00014143407,0.000012128924,0.000005871392,0.00014622074],"genre_scores_gemma":[0.99803716,0.00056130846,0.0009123884,0.00028700498,0.00015295311,0.0000030665226,0.000028319153,0.000010539351,0.0000072403586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990228,0.00022722832,0.00022218173,0.00031143517,0.0000889111,0.0001274611],"domain_scores_gemma":[0.99942374,0.000058559217,0.000108194305,0.00020846879,0.00015041478,0.000050648032],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052324357,0.000117298136,0.00024285787,0.00003825801,0.00008554743,0.0000059602053,0.00007457713,0.00017342619,0.0001442481],"category_scores_gemma":[0.00044316004,0.00007512566,0.000057203746,0.00015866014,0.00035579878,0.0000034311015,0.00009119263,0.00008621647,2.0511884e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004497899,0.000029038929,0.0020516221,0.000016733939,0.00006689575,1.6726183e-7,0.00024458618,9.947146e-7,0.9894942,0.00027080838,0.00012680574,0.0076531875],"study_design_scores_gemma":[0.0013185038,0.00049836014,0.010167429,0.00005708679,0.00011199138,0.000027322296,0.0010365003,0.0006288961,0.9734252,0.00051892985,0.012057158,0.00015260269],"about_ca_topic_score_codex":0.000036905392,"about_ca_topic_score_gemma":0.0000117051295,"teacher_disagreement_score":0.016068961,"about_ca_system_score_codex":0.0000058687324,"about_ca_system_score_gemma":0.00004992391,"threshold_uncertainty_score":0.30635357},"labels":[],"label_agreement":null},{"id":"W3201425577","doi":"10.1016/j.xpro.2021.100822","title":"Single tracer-based protocol for broad-spectrum kinase profiling in live cells with NanoBRET","year":2021,"lang":"en","type":"article","venue":"STAR Protocols","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Genentech; Kungliga Tekniska Högskolan; Ontario Genomics Institute; Janssen Pharmaceuticals; Merck KGaA; Genome Canada; Boehringer Ingelheim; McGill University; Takeda Pharmaceuticals U.S.A.; Pfizer; Deutsche Forschungsgemeinschaft; Bristol-Myers Squibb","keywords":"TRACER; Protocol (science); Kinase; Context (archaeology); Computer science; Chemistry; Profiling (computer programming); Computational biology; Chromatography; Physics; Biology; Biochemistry; Medicine; Nuclear physics; Operating system","score_opus":0.026786956461689167,"score_gpt":0.3008579778829136,"score_spread":0.2740710214212244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3201425577","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.044442423,0.0000072055795,0.011445901,0.000119291435,0.000030120884,0.94358903,0.000060003982,0.00003103382,0.00027497608],"genre_scores_gemma":[0.016627392,1.3341995e-7,0.032969724,0.00015617983,0.00013728903,0.9497048,0.00006270876,0.00005530377,0.00028641763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984008,0.000105286046,0.00031169335,0.0005765367,0.00017779865,0.00042790105],"domain_scores_gemma":[0.99924,0.000021994945,0.00013389466,0.00036474073,0.00014863035,0.000090759386],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028096145,0.00023839755,0.00023797195,0.000044666584,0.00008704548,0.0000772875,0.00016017286,0.00017278036,0.00017591288],"category_scores_gemma":[0.00004798546,0.00020804505,0.000106372914,0.00014064406,0.000039049355,0.000007500115,0.000044999575,0.00012106583,0.000004624598],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001145687,0.00035518804,0.00015677958,0.00032963307,0.000016777714,0.000024097057,0.00004927165,0.00029629303,0.99678445,0.00008200753,0.00014350795,0.00061631086],"study_design_scores_gemma":[0.0041931,0.0022952927,0.000008677354,0.0002720693,0.00000504846,0.000004273888,0.00010494312,0.00032592312,0.95271945,0.00020614735,0.03956494,0.0003001509],"about_ca_topic_score_codex":0.00000852467,"about_ca_topic_score_gemma":0.000093644674,"teacher_disagreement_score":0.044065014,"about_ca_system_score_codex":0.000043449032,"about_ca_system_score_gemma":0.00044716286,"threshold_uncertainty_score":0.84838307},"labels":[],"label_agreement":null},{"id":"W3203078114","doi":"10.1016/j.molcel.2021.09.007","title":"Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors","year":2021,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":105,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Moonshot Research and Development Program; Science and Engineering Research Board; Japan Society for the Promotion of Science; National Health and Medical Research Council; Canadian Institutes of Health Research; The Wellcome Trust DBT India Alliance; Japan Science and Technology Agency; Lady Tata Memorial Trust; Daiichi Sankyo Foundation of Life Science; Wellcome Trust; Council of Scientific and Industrial Research, India; Fonds de Recherche du Québec - Santé; Department of Science and Technology, Ministry of Science and Technology, India; Department of Biotechnology, Ministry of Science and Technology, India; Indian Institute of Technology Kanpur; Japan Agency for Medical Research and Development; Uehara Memorial Foundation; European Molecular Biology Organization","keywords":"G protein-coupled receptor; Biology; Receptor; Transmembrane protein; Arrestin; Transmembrane domain; Signal transduction; Cell biology; Biochemistry","score_opus":0.01103722955922016,"score_gpt":0.21938420263854283,"score_spread":0.20834697307932268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3203078114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97781056,0.0020722593,0.014204041,0.000239525,0.00055693317,0.00021724665,0.000009834173,0.000027806753,0.0048617856],"genre_scores_gemma":[0.98963535,0.0003688387,0.0033231296,0.0006623967,0.00024550036,0.000027417664,0.00035663598,0.00008110963,0.0052996404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99808806,0.0001278463,0.000344811,0.0007023897,0.00027136554,0.00046554327],"domain_scores_gemma":[0.9989109,0.000018869783,0.00009667954,0.0006070804,0.00014793024,0.00021851397],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022133633,0.00029700907,0.00029175056,0.000043737626,0.00013490595,0.000051712257,0.000260199,0.00029132533,0.0011601605],"category_scores_gemma":[0.00007330627,0.00030569738,0.00030435188,0.0002117317,0.000055328757,0.0000037541643,0.00018688726,0.00017947155,0.00010720113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058584126,0.00007247422,0.0000750945,0.000042546264,0.000053944157,0.0001484833,0.00005465299,0.00052357,0.9960652,0.000024386281,0.0010183939,0.0018626832],"study_design_scores_gemma":[0.00086858205,0.0001593011,0.000023461767,0.000020094405,0.00004123073,0.00002922835,0.00004658376,0.00023589552,0.90544194,0.000039201943,0.09273687,0.00035761527],"about_ca_topic_score_codex":0.000020348147,"about_ca_topic_score_gemma":0.00003222436,"teacher_disagreement_score":0.09171848,"about_ca_system_score_codex":0.000037853126,"about_ca_system_score_gemma":0.0002259257,"threshold_uncertainty_score":0.9999395},"labels":[],"label_agreement":null},{"id":"W3204093502","doi":"10.1139/cjpp-2021-0299","title":"Acute and chronic metabolic effects of carvedilol in high-fructose, high-fat diet–fed mice: implication of β-arrestin2 pathway","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Carvedilol; Insulin resistance; Internal medicine; Endocrinology; Dyslipidemia; Insulin; Protein kinase B; Medicine; Insulin receptor; Adipose tissue; Fructose; Metabolic syndrome; Chemistry; Diabetes mellitus; Signal transduction; Heart failure; Biochemistry","score_opus":0.004582854780584806,"score_gpt":0.2360477036389473,"score_spread":0.2314648488583625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204093502","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98727906,0.011813541,0.000048935006,0.00011798203,0.0006018899,0.00009646942,0.00003353812,7.298865e-7,0.000007859304],"genre_scores_gemma":[0.99767417,0.0016299984,0.00019971887,0.00013644154,0.0002911811,0.0000058566998,0.000030662308,0.000010298078,0.000021670156],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990253,0.00020053561,0.00032588776,0.00018849285,0.000037710408,0.00022209536],"domain_scores_gemma":[0.9992492,0.000057657442,0.00026217717,0.000088124136,0.00016231019,0.00018048163],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001300487,0.000121966616,0.00039905973,0.00011117062,0.000044836874,0.0000032092692,0.000110794856,0.0001863112,0.00015906275],"category_scores_gemma":[0.00003378129,0.00011549481,0.000059229977,0.000095597396,0.00016896015,0.000007956628,0.00003301547,0.00016820755,2.954665e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014242438,0.000021159569,0.00048867246,0.000121955614,0.00020770654,0.0000339878,0.000073206036,0.000045938334,0.99749273,0.0003580705,0.00016677406,0.0008473882],"study_design_scores_gemma":[0.0014436067,0.0007948359,0.0067926673,0.000025218393,0.00011456229,0.000058940826,0.000018470815,0.0000117997515,0.98915464,0.0007561411,0.00073453016,0.00009458695],"about_ca_topic_score_codex":0.00034675078,"about_ca_topic_score_gemma":0.000827634,"teacher_disagreement_score":0.010395117,"about_ca_system_score_codex":0.000015937338,"about_ca_system_score_gemma":0.0005322542,"threshold_uncertainty_score":0.47097415},"labels":[],"label_agreement":null},{"id":"W3204953505","doi":"10.1021/acscentsci.1c00802","title":"Probe Confined Dynamic Mapping for G Protein-Coupled Receptor Allosteric Site Prediction","year":2021,"lang":"en","type":"article","venue":"ACS Central Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Engineering and Physical Sciences Research Council; European Commission; Queen's University; Queen's University Belfast; Max-Planck-Gesellschaft; Medical Research Council; Barts Charity","keywords":"Allosteric regulation; G protein-coupled receptor; Allosteric enzyme; Chemistry; Allosteric modulator; Biophysics; Small molecule; Receptor; Biochemistry; Biology","score_opus":0.009410523533694492,"score_gpt":0.22891381267290095,"score_spread":0.21950328913920647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3204953505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9271956,0.00018430426,0.07135241,0.00020598281,0.00042175647,0.00051722187,0.000030427947,0.000019421423,0.00007288659],"genre_scores_gemma":[0.9870042,0.000042313728,0.011487372,0.0001379653,0.00013211483,0.00006806483,0.00018096538,0.000012047234,0.0009349344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986748,0.000019929112,0.00017539234,0.00047910423,0.00019438387,0.0004563991],"domain_scores_gemma":[0.99940425,0.0000040563896,0.00007221275,0.00020492861,0.00019600028,0.00011854774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027988106,0.000112832975,0.00009992787,0.00002753447,0.00022372461,0.00008742764,0.00018997307,0.00007636412,0.00007843344],"category_scores_gemma":[0.00014773886,0.00010634054,0.000059078913,0.0002449458,0.000093279275,0.000014891011,0.00009495504,0.000050570157,0.000005423537],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022424794,0.000023577857,0.00012744451,0.000018413095,0.0000074134678,8.2078043e-7,0.00006493773,0.000037176203,0.99794483,0.00018784935,0.000054055996,0.0015110418],"study_design_scores_gemma":[0.0003476566,0.00014797588,0.0006064505,0.000030513767,0.000005442395,0.0000073246333,0.0000858373,0.0036777533,0.98755395,0.000081921724,0.007315232,0.00013992675],"about_ca_topic_score_codex":0.000006435697,"about_ca_topic_score_gemma":0.000009762445,"teacher_disagreement_score":0.059865035,"about_ca_system_score_codex":0.00004206568,"about_ca_system_score_gemma":0.00026651676,"threshold_uncertainty_score":0.43364415},"labels":[],"label_agreement":null},{"id":"W3205077902","doi":"10.1101/2020.04.20.052027","title":"Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec; Institute for Research in Immunology and Cancer; Université du Québec à Montréal","funders":"Canadian Institutes of Health Research; H. Lundbeck A/S; Novo Nordisk Fonden; Novo Nordisk; Lundbeckfonden","keywords":"G protein-coupled receptor; Effector; Arrestin; Functional selectivity; Receptor; Computational biology; Signal transduction; G protein; Cell biology; Biology; Chemistry; Biochemistry","score_opus":0.014146048185222318,"score_gpt":0.2242369225817993,"score_spread":0.21009087439657698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3205077902","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99117863,0.0025198327,0.0041992175,0.00026106095,0.0002531834,0.0013562982,0.0001481416,0.000081587794,0.0000020716545],"genre_scores_gemma":[0.9886012,0.0005770506,0.010108225,0.000070377195,0.0003614635,0.00015261977,0.000003494588,0.000121652665,0.0000039382853],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99760306,0.00013646294,0.0006033978,0.000988622,0.00030301503,0.00036545555],"domain_scores_gemma":[0.99841416,0.00003274148,0.00039488607,0.00063125393,0.00031175776,0.00021518332],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00054273417,0.0004890213,0.0005715961,0.0000986443,0.00009735689,0.000073624506,0.00032814263,0.0006395054,0.000017692664],"category_scores_gemma":[0.00022613742,0.0004863631,0.00015566823,0.00018320262,0.00014360673,0.0000075645416,0.00019651758,0.00043888294,0.000005292658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016269712,0.000060895403,0.00032140265,0.0010116049,0.00016308202,0.000007263768,0.000010606458,0.00012994507,0.99789584,0.0002169146,0.000012725542,0.000007048726],"study_design_scores_gemma":[0.0004966745,0.00025545878,0.002045354,0.000705653,0.000087358254,3.0775116e-8,0.0000039815354,0.0009690808,0.99450845,0.0000036252823,0.0004096444,0.0005146821],"about_ca_topic_score_codex":0.000023347975,"about_ca_topic_score_gemma":0.0000011768062,"teacher_disagreement_score":0.0059090075,"about_ca_system_score_codex":0.000026454318,"about_ca_system_score_gemma":0.00036530147,"threshold_uncertainty_score":0.9997588},"labels":[],"label_agreement":null},{"id":"W3205834419","doi":"10.1016/j.str.2021.10.002","title":"Structural evidence for visual arrestin priming via complexation of phosphoinositols","year":2021,"lang":"en","type":"article","venue":"Structure","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Argonne National Laboratory; National Institute of General Medical Sciences; National Eye Institute; Natural Sciences and Engineering Research Council of Canada; Ministry of Science, ICT and Future Planning; National Institutes of Health; University of Toronto; National Research Foundation of Korea; Canada Excellence Research Chairs, Government of Canada; Office of Science; U.S. Department of Veterans Affairs; American Pain Society; Biological and Environmental Research; Research to Prevent Blindness; Canadian Institutes of Health Research; Mitacs","keywords":"Rhodopsin; Biology; Priming (agriculture); Biophysics; Biochemistry; Retinal","score_opus":0.03389248355797711,"score_gpt":0.3260190397020533,"score_spread":0.29212655614407623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3205834419","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97335654,0.000904881,0.025164353,0.000029169096,0.000342061,0.00015256129,0.000031272346,0.000005852502,0.000013314217],"genre_scores_gemma":[0.98505044,0.000011115113,0.014326452,0.0000639278,0.00027612442,0.00000480642,0.00021324912,0.000013593507,0.000040286915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928516,0.00002909303,0.00017991631,0.00025068197,0.0001103968,0.00014477265],"domain_scores_gemma":[0.9994803,0.000025738087,0.000115164505,0.00015367361,0.00018715057,0.000037937123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005176575,0.00010891499,0.0001361649,0.000014097968,0.00007419281,0.000018110526,0.00009447969,0.000111628164,0.00014094343],"category_scores_gemma":[0.0001553098,0.00010051591,0.00008157411,0.00005951808,0.000026383981,0.0000050527347,0.000048522852,0.000053521475,2.957623e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060570314,0.0000027985677,0.0009111039,0.000052772768,0.00002173539,7.366818e-7,0.000048370537,0.00027523137,0.9941708,0.00022131205,0.000073244,0.0041613327],"study_design_scores_gemma":[0.000255624,0.00011753012,0.0023010634,0.000040282655,0.000019128047,0.000017344964,0.00005580748,0.0010596308,0.99453473,0.0011558549,0.00032406684,0.00011892813],"about_ca_topic_score_codex":0.000008276428,"about_ca_topic_score_gemma":0.000014599167,"teacher_disagreement_score":0.011693909,"about_ca_system_score_codex":0.000008734527,"about_ca_system_score_gemma":0.00007359629,"threshold_uncertainty_score":0.40989196},"labels":[],"label_agreement":null},{"id":"W3207168114","doi":"10.1002/cpz1.268","title":"Evaluating Sequential Response Learning in the Rodent Operant Touchscreen System","year":2021,"lang":"en","type":"article","venue":"Current Protocols","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Touchscreen; Task (project management); Computer science; Operant conditioning; Sequence (biology); Sequence learning; Neuroscience; Artificial intelligence; Psychology; Human–computer interaction; Biology; Reinforcement; Engineering","score_opus":0.10125414968988601,"score_gpt":0.4168865135670214,"score_spread":0.3156323638771354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3207168114","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9676435,0.0005913504,0.006260685,0.000121386496,0.0002274153,0.02488513,0.000006740163,0.000025741549,0.00023805087],"genre_scores_gemma":[0.9565308,0.000008950886,0.0007104107,0.000054327124,0.0003951329,0.041989166,0.00006761195,0.000022883092,0.00022071764],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99760175,0.0012081544,0.0002966441,0.00035832418,0.00028863957,0.00024647426],"domain_scores_gemma":[0.9994159,0.000031165426,0.00008759036,0.00031321772,0.00011093116,0.000041248786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0021028195,0.00013522342,0.00014175916,0.000027150194,0.0001417044,0.00011590029,0.000243815,0.000076258184,0.00006265758],"category_scores_gemma":[0.00028166128,0.00010205431,0.00009663226,0.00012015885,0.000016805772,0.0000049525966,0.00013255056,0.00022557512,0.00001199801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035061667,0.00007143677,0.00048650775,0.000097681695,0.000011750688,0.000016875554,0.00023840879,0.0014534728,0.9854274,0.00020357543,0.0000824751,0.011559801],"study_design_scores_gemma":[0.0020108682,0.000728928,0.0007097808,0.0007604864,0.000018379425,0.000073160256,0.0016029237,0.0039090263,0.90345675,0.000025513182,0.08636193,0.00034225368],"about_ca_topic_score_codex":0.000006330673,"about_ca_topic_score_gemma":0.0000063576895,"teacher_disagreement_score":0.08627946,"about_ca_system_score_codex":0.000036336278,"about_ca_system_score_gemma":0.00022491906,"threshold_uncertainty_score":0.4161654},"labels":[],"label_agreement":null},{"id":"W3207364816","doi":"10.1002/jnr.24964","title":"Tackling the opioid crisis: Novel mechanisms and clinical perspectives","year":2021,"lang":"en","type":"article","venue":"Journal of Neuroscience Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Opioid; Business; Medicine; Internal medicine","score_opus":0.08930536439155558,"score_gpt":0.4186976544974207,"score_spread":0.3293922901058651,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3207364816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9635809,0.0021347825,0.031395905,0.0021820546,0.00052862515,0.00007256813,0.0000020854095,0.0000017793108,0.00010131066],"genre_scores_gemma":[0.99282604,0.0034853178,0.0027902378,0.00032309428,0.00037684685,0.000001108114,2.1612641e-7,0.000008941997,0.00018818298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99834555,0.0002789609,0.00028138023,0.00026936334,0.00056657026,0.00025814713],"domain_scores_gemma":[0.9988079,0.00009112212,0.000102416605,0.00019617288,0.00066677923,0.00013562271],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0034469995,0.000067428016,0.00012283027,0.00005973297,0.0002945789,0.00015871189,0.0003528485,0.0000663958,0.000012972679],"category_scores_gemma":[0.0016345119,0.000043629538,0.000108614215,0.00024562769,0.00021652172,0.000012278067,0.00025703578,0.00046014707,7.6410913e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022774673,0.000073018295,0.00006123923,0.0000030679207,0.0000065803656,0.000024925082,0.00010999944,0.000024143876,0.9974164,0.0010084863,0.00032719158,0.00092217355],"study_design_scores_gemma":[0.00080928724,0.0021574972,0.0030569187,0.000052674182,0.000020672729,0.0012689402,0.014808002,0.0011277084,0.9505713,0.0033017418,0.022635043,0.00019023343],"about_ca_topic_score_codex":0.0000024731369,"about_ca_topic_score_gemma":0.0000017193388,"teacher_disagreement_score":0.046845116,"about_ca_system_score_codex":0.0000103445245,"about_ca_system_score_gemma":0.0003360735,"threshold_uncertainty_score":0.22656925},"labels":[],"label_agreement":null},{"id":"W3209179037","doi":"10.1161/hypertensionaha.121.17977","title":"Angiotensin II Type 1 Receptor Tachyphylaxis Is Defined by Agonist Residence Time","year":2021,"lang":"en","type":"article","venue":"Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Tachyphylaxis; Agonist; Receptor; G protein-coupled receptor; Internalization; Angiotensin II; Signal transduction; Endogenous agonist","score_opus":0.012268572184386116,"score_gpt":0.21621548446452754,"score_spread":0.20394691228014142,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209179037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911337,0.0056966273,0.00031994918,0.0014524511,0.00052062166,0.000099806704,0.000040260406,0.00003530587,0.0007013161],"genre_scores_gemma":[0.9565997,0.0011067913,0.010041646,0.0050646793,0.00043145294,0.000005443761,0.0010989616,0.00007380436,0.025577493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988121,0.000060213748,0.00018775045,0.0004995084,0.00017954572,0.00026090088],"domain_scores_gemma":[0.9990709,0.000013072568,0.00005835882,0.00042021577,0.0003335015,0.000103967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116394694,0.00017439401,0.00019864771,0.000022365462,0.00023526076,0.000035999397,0.00011562165,0.00022148965,0.0007458537],"category_scores_gemma":[0.00014744437,0.0001639843,0.00010974883,0.00016176754,0.00003581997,0.000005078607,0.00016896799,0.00009167052,0.00024127554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032341697,0.00003944774,0.000017262762,0.0000026894227,0.000014935839,0.000009098992,0.000014365101,0.000001318459,0.6621907,0.000009063285,0.33675835,0.0009104268],"study_design_scores_gemma":[0.00019912637,0.00024477928,0.000026890553,0.000022721873,0.0000129755135,0.00005030671,0.000022386712,0.00010084917,0.7458676,0.000030344987,0.25324515,0.00017686552],"about_ca_topic_score_codex":0.000031138086,"about_ca_topic_score_gemma":0.0000034258587,"teacher_disagreement_score":0.08367692,"about_ca_system_score_codex":0.000012642527,"about_ca_system_score_gemma":0.000087641754,"threshold_uncertainty_score":0.8166575},"labels":[],"label_agreement":null},{"id":"W3209404676","doi":"10.3389/fnbeh.2021.744715","title":"A Novel Assay Allowing Drug Self-Administration, Extinction, and Reinstatement Testing in Head-Restrained Mice","year":2021,"lang":"en","type":"article","venue":"Frontiers in Behavioral Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Langara College","funders":"National Institute of General Medical Sciences; National Institute on Drug Abuse; National Institutes of Health; Medical University of South Carolina","keywords":"Self-administration; Extinction (optical mineralogy); Addiction; Neuroscience; Lever; Psychology; Heroin; Drug; Substance abuse; Pharmacology; Medicine; Biology; Psychiatry; Physics","score_opus":0.027700538635693665,"score_gpt":0.28742170090067554,"score_spread":0.2597211622649819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209404676","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98140126,0.00015266096,0.017450726,0.0001118759,0.00067299383,0.00013916043,0.0000070969586,0.000014175161,0.00005002832],"genre_scores_gemma":[0.94734174,0.000042083168,0.052204534,0.00018068885,0.000034619385,0.000019188079,0.000014939565,0.000012230829,0.00014995402],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986524,0.000074337346,0.00028235718,0.00054813595,0.00016823354,0.00027451245],"domain_scores_gemma":[0.99963754,0.000007873087,0.00006687586,0.00015262063,0.000059326532,0.00007576881],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040313107,0.00013374725,0.00012990441,0.00006782478,0.000104359,0.00008172861,0.00013062709,0.00006291102,0.0000029957419],"category_scores_gemma":[0.00013083567,0.00014936284,0.000026957263,0.0003360372,0.000054890814,0.000023795805,0.0000837568,0.0001247576,1.6815248e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010516501,0.00015604995,0.040698595,0.000006693562,6.3627147e-7,0.000044031618,0.000100276906,0.00015202917,0.95676655,0.000007234102,0.000057947396,0.0019994273],"study_design_scores_gemma":[0.0016486623,0.00049642404,0.072580755,0.00010135282,0.000020538191,0.00015586254,0.0012523055,0.0072858413,0.9108893,0.00010135492,0.004841428,0.0006261756],"about_ca_topic_score_codex":0.000037445472,"about_ca_topic_score_gemma":0.0001007253,"teacher_disagreement_score":0.045877263,"about_ca_system_score_codex":0.000034353372,"about_ca_system_score_gemma":0.00016929679,"threshold_uncertainty_score":0.60908395},"labels":[],"label_agreement":null},{"id":"W3210638413","doi":"10.1016/j.ymeth.2021.10.009","title":"Luciferase-based GloSensor™ cAMP assay: Temperature optimization and application to cell-based kinetic studies","year":2021,"lang":"en","type":"article","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Allosteric regulation; Biosensor; Luciferase; Intracellular; Receptor; Second messenger system; Signal transduction; Chemistry; Adenosine; Transfection; Cyclic adenosine monophosphate; Cytosol; Cell biology; Biophysics; Biology; Biochemistry; Enzyme","score_opus":0.014874090253094323,"score_gpt":0.33270909828209017,"score_spread":0.31783500802899584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210638413","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.066307716,0.0024329666,0.93045044,0.00038042862,0.000117800075,0.00019368507,0.0000087224,0.000016594988,0.00009167288],"genre_scores_gemma":[0.26242086,0.00009065303,0.73561275,0.0012222835,0.00013294663,0.000063144566,0.00015101278,0.000024231851,0.00028207674],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988056,0.00038975538,0.00015823568,0.00040331294,0.00009423817,0.00014889566],"domain_scores_gemma":[0.999316,0.00006215096,0.000050059498,0.00027193528,0.00021927847,0.00008061269],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00052442466,0.00014360339,0.00016912963,0.00003635202,0.00009793073,0.000038296082,0.00006122591,0.00013931857,0.000032024822],"category_scores_gemma":[0.00022843461,0.0001346054,0.000050700928,0.00015748011,0.000021659307,0.0000018982817,0.000041643383,0.00006781902,0.0000018752124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020068966,0.000026888012,0.00004045459,0.000036178568,0.000015782465,0.0000016891469,0.000027140006,0.097494215,0.8989529,0.000017049624,0.0002265201,0.003141119],"study_design_scores_gemma":[0.0003361281,0.000100991674,0.000025981479,0.000015455307,0.00002670938,0.000002136532,0.00009902551,0.019732626,0.9728763,0.000036197856,0.0065844525,0.00016401311],"about_ca_topic_score_codex":0.0000030800693,"about_ca_topic_score_gemma":0.0000031956372,"teacher_disagreement_score":0.19611315,"about_ca_system_score_codex":0.000015593145,"about_ca_system_score_gemma":0.00006636798,"threshold_uncertainty_score":0.5489049},"labels":[],"label_agreement":null},{"id":"W3210767135","doi":"10.1101/2021.10.25.465698","title":"Regulation of skeletal muscle metabolism and contraction performance via teneurin-latrophilin action","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; York University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Skeletal muscle; Cell biology; Biology; Muscle contraction; Myocyte; Internal medicine; Endocrinology; Chemistry; Medicine","score_opus":0.009552342012973353,"score_gpt":0.20930844256626457,"score_spread":0.1997561005532912,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210767135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98781914,0.0024082642,0.00850766,0.000022660508,0.0008951618,0.00028490176,0.000026153053,0.000033635522,0.0000024120072],"genre_scores_gemma":[0.99441427,0.0018647611,0.0030133738,0.000028316575,0.00057502784,0.000034653,0.000003765593,0.00005999986,0.0000058077912],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983845,0.00009857768,0.00039735442,0.0006619562,0.00021881776,0.00023880432],"domain_scores_gemma":[0.99853873,0.000008991556,0.00040684053,0.00055413763,0.0003880001,0.00010332439],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029214297,0.00030565695,0.00035925952,0.00010033893,0.00010087546,0.000069023,0.00013872248,0.0005163684,0.00003462641],"category_scores_gemma":[0.00005642691,0.0003389815,0.00013073448,0.000119077915,0.00006136679,0.000022763013,0.00020213999,0.0002963043,0.0000016544686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002786875,0.000051493076,0.00037685345,0.00020467551,0.00008608447,0.0000016264622,0.0000030449967,0.00034573246,0.9987659,0.000047200432,0.0000065603385,0.00008297569],"study_design_scores_gemma":[0.00030485186,0.000059549177,0.13291919,0.00008177264,0.000084645835,6.407063e-8,0.0000030614485,0.001187943,0.86364233,0.0000010593931,0.0014219935,0.00029351015],"about_ca_topic_score_codex":0.000026899002,"about_ca_topic_score_gemma":0.0000024220817,"teacher_disagreement_score":0.13512354,"about_ca_system_score_codex":0.000027591434,"about_ca_system_score_gemma":0.00016378528,"threshold_uncertainty_score":0.99990624},"labels":[],"label_agreement":null},{"id":"W3210919302","doi":"10.1016/bs.mcb.2021.06.018","title":"Identifying Plasmodium falciparum receptor activation using bioluminescence resonance energy transfer (BRET)-based biosensors in HEK293 cells","year":2021,"lang":"en","type":"article","venue":"Methods in cell biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"","keywords":"Multicellular organism; G protein-coupled receptor; Biology; Organism; Plasmodium falciparum; Computational biology; Protozoa; Bioluminescence; Model organism; Identification (biology); Receptor; Malaria; Cell; Gene; Genetics; Ecology; Immunology","score_opus":0.04538162992519281,"score_gpt":0.3403253303923478,"score_spread":0.294943700467155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3210919302","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.58004105,0.0008909349,0.41816622,0.00004310997,0.00058809813,0.00009844448,0.000015105901,0.0000105544605,0.0001465045],"genre_scores_gemma":[0.7124709,0.00040888507,0.2862225,0.00032211698,0.00013583174,0.000027594153,0.0001501765,0.00004071466,0.00022127922],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996758,0.0012664107,0.0005296412,0.00083326636,0.000088275265,0.00052439794],"domain_scores_gemma":[0.99923766,0.00014732436,0.00009290702,0.0003647377,0.000087759014,0.000069592366],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009113649,0.000276267,0.00038922805,0.0001917944,0.00007370611,0.00002597643,0.00023698791,0.0005435689,0.00011441326],"category_scores_gemma":[0.00013162855,0.00029166104,0.00013197359,0.00048393637,0.000095467374,0.000009225637,0.00008364755,0.00021891906,0.0000023965497],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107215965,0.00009051194,0.0007623353,0.000032412587,0.00000728877,0.000005441812,0.000054349894,0.00080146384,0.9927215,0.0001416175,0.00001977191,0.0052560912],"study_design_scores_gemma":[0.0007313768,0.00009867187,0.000054426007,0.00006660381,0.000006292451,0.0000019959261,0.00014087331,0.0030155971,0.9827223,0.00019325597,0.012634392,0.00033426084],"about_ca_topic_score_codex":0.00022382694,"about_ca_topic_score_gemma":0.000111329355,"teacher_disagreement_score":0.13242988,"about_ca_system_score_codex":0.000070444206,"about_ca_system_score_gemma":0.00017073915,"threshold_uncertainty_score":0.99995357},"labels":[],"label_agreement":null},{"id":"W3211592009","doi":"","title":"Divergent conformations of the arrestin-rhodopsin complex in solution","year":2019,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Rhodopsin; Arrestin; Chemistry; Biophysics; Biology; G protein-coupled receptor; Biochemistry; Retinal; Receptor","score_opus":0.04069062554960138,"score_gpt":0.31555078966010713,"score_spread":0.27486016411050573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3211592009","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980086,0.000025373136,0.000026080494,0.000108126565,0.00030866306,0.00023461774,0.0000060354273,0.0000028835118,0.0012796004],"genre_scores_gemma":[0.9990935,0.0000018086631,0.00063860574,0.00010435807,0.000019425695,0.000008987402,0.000008974831,0.0000043237496,0.00012005825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896276,0.000111825546,0.00022785546,0.00025765505,0.00020323695,0.00023664525],"domain_scores_gemma":[0.99944794,0.000020370086,0.0001511369,0.0001956421,0.00012037201,0.00006455017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004977606,0.000096578544,0.00012148588,0.000060207487,0.00013392756,0.000011307363,0.00038771585,0.000070203445,0.0001615488],"category_scores_gemma":[0.00022130177,0.00007274858,0.000045220913,0.00039800338,0.0011891734,0.000014897822,0.00026168855,0.00009047102,0.000016965523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007634098,0.00002587045,0.05205479,0.0000047945596,0.0000033975136,6.0529965e-7,0.00017328675,0.00028102173,0.9470501,0.00034320168,0.000018387247,0.000036934976],"study_design_scores_gemma":[0.00017140956,0.0001951455,0.13826127,0.000019655765,0.00000226127,0.000018331191,0.00015640008,0.0013455031,0.85895944,0.00072025217,0.000066780536,0.00008355569],"about_ca_topic_score_codex":0.00008982445,"about_ca_topic_score_gemma":0.000006068006,"teacher_disagreement_score":0.08809065,"about_ca_system_score_codex":0.000028613586,"about_ca_system_score_gemma":0.00022995834,"threshold_uncertainty_score":0.4381559},"labels":[],"label_agreement":null},{"id":"W3212353708","doi":"10.3389/fphar.2021.741460","title":"Monoamine Oxidase-B Inhibitor Reduction in Pro-Inflammatory Cytokines Mediated by Inhibition of cAMP-PKA/EPAC Signaling","year":2021,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Monoamine oxidase; Chemistry; Pharmacology; Signal transduction; Enzyme; Medicine; Biochemistry","score_opus":0.0065660591621298815,"score_gpt":0.2386175847462216,"score_spread":0.23205152558409173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3212353708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917774,0.002934158,0.0028506648,0.00015370491,0.0019131383,0.00027947628,0.000029502155,0.0000128899155,0.000049067854],"genre_scores_gemma":[0.9957587,0.0006509562,0.0023661759,0.000112742215,0.00034461555,0.00008121771,0.0004931474,0.000030120582,0.00016230422],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841064,0.00023552988,0.0005005612,0.0004199901,0.00012825622,0.00030503594],"domain_scores_gemma":[0.9994976,0.000013629042,0.00017441115,0.0001255488,0.00012074401,0.00006804608],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032898615,0.00018189846,0.00030318278,0.00017800751,0.00003392891,0.000007760034,0.00009036279,0.00028929222,0.00015504676],"category_scores_gemma":[0.00006261112,0.0002055938,0.00007234221,0.00027790814,0.000080961014,0.000014181632,0.00006661826,0.00019552164,0.0000016939938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023025312,0.00014469984,0.0022516942,0.000055094526,0.000046999885,0.00004268588,0.00012515424,0.0004009989,0.97786653,0.00000549271,0.018133208,0.0006972159],"study_design_scores_gemma":[0.0017620994,0.00012762891,0.00007826394,0.00004175696,0.000020673344,0.000015342866,0.00037319586,0.00047807104,0.991412,0.00010367516,0.0053919773,0.00019531471],"about_ca_topic_score_codex":0.000013130763,"about_ca_topic_score_gemma":0.000009971643,"teacher_disagreement_score":0.013545497,"about_ca_system_score_codex":0.00007252494,"about_ca_system_score_gemma":0.00013577325,"threshold_uncertainty_score":0.8383872},"labels":[],"label_agreement":null},{"id":"W3213113520","doi":"10.3791/62448","title":"Screening Peptides that Activate MRGPRX2 using Engineered HEK Cells","year":2021,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Receptor; Peptide; HEK 293 cells; G protein-coupled receptor; Cell biology; Calcium in biology; Cell culture; In vitro; Chemistry; Biology; Molecular biology; Biochemistry","score_opus":0.04572878765413672,"score_gpt":0.3878261915230718,"score_spread":0.34209740386893506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3213113520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92228377,0.0021750578,0.07486122,0.000011727572,0.0005173789,0.000050599607,0.0000032685239,0.0000046852324,0.00009226882],"genre_scores_gemma":[0.95138395,0.0002899376,0.04749527,0.00013735502,0.00036515656,0.0000014477478,0.000010727118,0.0000366769,0.00027950355],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988192,0.00010385101,0.00036075167,0.00018754389,0.00028833761,0.00024032583],"domain_scores_gemma":[0.99922526,0.000015613336,0.0003024302,0.0001598673,0.00016139832,0.00013542015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023070059,0.00017209121,0.00027466702,0.000065667446,0.00008422578,0.000067761284,0.00015070946,0.00011449431,0.00019459176],"category_scores_gemma":[0.0000460577,0.00015866155,0.00023418096,0.0000814383,0.000018170913,0.000017421828,0.00008707378,0.000118174416,0.0000017917887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013860936,0.0000835005,0.00006593384,0.000009848647,0.00018531471,0.000046006164,0.00016387859,0.00051960896,0.99803877,0.000011525714,0.00027282443,0.0004642004],"study_design_scores_gemma":[0.0012615712,0.00015975747,0.000017292994,0.00010323396,0.000028042215,0.00010867287,0.0008599736,0.0002577939,0.9929003,0.000016938096,0.004113117,0.00017331877],"about_ca_topic_score_codex":0.000005451949,"about_ca_topic_score_gemma":3.0478398e-7,"teacher_disagreement_score":0.029100137,"about_ca_system_score_codex":0.000026345551,"about_ca_system_score_gemma":0.00011261948,"threshold_uncertainty_score":0.64700305},"labels":[],"label_agreement":null},{"id":"W3214268594","doi":"10.1096/fba.2021-00073","title":"Critical cysteines in the functional interaction of adenylyl cyclase isoform 6 with Gαs","year":2021,"lang":"en","type":"article","venue":"FASEB BioAdvances","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Heart and Stroke Foundation of Canada; Research Manitoba","keywords":"Adenylyl cyclase; Cysteine; Gene isoform; Protein subunit; Mutagenesis; Biochemistry; ADCY6; Intracellular; Cell biology; Chemistry; Gs alpha subunit; Biology; Signal transduction; Enzyme; Mutation","score_opus":0.013565518151899228,"score_gpt":0.2670567570438715,"score_spread":0.2534912388919723,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3214268594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992086,0.001254187,0.005109832,0.00041627823,0.0002429834,0.000059803773,0.000016283182,0.000003942095,0.00081067084],"genre_scores_gemma":[0.99822885,0.00010412249,0.0010588587,0.0002138464,0.00016078014,0.000014588409,0.0000793344,0.000005879245,0.00013374098],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99941343,0.000042209915,0.00013680686,0.00017491223,0.00012215936,0.00011047717],"domain_scores_gemma":[0.9996678,0.000039043014,0.00003847066,0.00013188054,0.00009730405,0.000025507943],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009150564,0.00007807892,0.00008521856,0.00002195269,0.000041473188,0.000017792616,0.00006705764,0.000047971793,0.000106814136],"category_scores_gemma":[0.00012322466,0.000050460105,0.00004140402,0.00009563195,0.00006140655,0.000010848401,0.000022213051,0.000055534816,0.0000019652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013694142,0.000085018604,0.0013986863,0.00002767465,0.000017843826,0.000017041435,0.000051494044,0.00018810775,0.99470454,0.0012767612,0.000196833,0.001899063],"study_design_scores_gemma":[0.00028586632,0.00028381866,0.0006462936,0.000045511428,0.000011364313,0.00008201631,0.0018816901,0.00006242144,0.98461956,0.00022581503,0.011761962,0.00009368574],"about_ca_topic_score_codex":0.0000077937575,"about_ca_topic_score_gemma":0.0001177207,"teacher_disagreement_score":0.01156513,"about_ca_system_score_codex":0.0000050373274,"about_ca_system_score_gemma":0.00005271762,"threshold_uncertainty_score":0.20577034},"labels":[],"label_agreement":null},{"id":"W3215002820","doi":"10.1101/2021.11.26.470153","title":"Synaptic Activity-Dependent Changes in the Hippocampal Palmitoylome","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Palmitoylation; Synaptic plasticity; Synapse; Neuroscience; Biology; AMPA receptor; Cell biology; Postsynaptic density; Receptor; Biochemistry; Glutamate receptor","score_opus":0.01301015656638907,"score_gpt":0.22194563106647147,"score_spread":0.2089354745000824,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215002820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937874,0.0024890504,0.0016537486,0.00030232238,0.001088767,0.00056348613,0.000060226015,0.00004467297,0.000010289447],"genre_scores_gemma":[0.99689794,0.00083382265,0.0006551427,0.00039481043,0.0008720882,0.00024239575,0.0000018500796,0.00009618691,0.0000057477987],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99718827,0.00040105413,0.00031571847,0.0010840526,0.00042267598,0.0005882382],"domain_scores_gemma":[0.99801415,0.00003614418,0.00025484053,0.0013664411,0.00019473558,0.00013368626],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00084871147,0.00051991834,0.00046056215,0.0001357594,0.00013114148,0.0002898893,0.0007925931,0.00075009424,0.0000802192],"category_scores_gemma":[0.00015922176,0.00046346776,0.00018746775,0.0002447625,0.00006912459,0.00000791213,0.0006231667,0.0007911323,0.000012611351],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002814414,0.00013763759,0.00093782373,0.00013411822,0.0001742601,0.00009670151,0.00002175568,0.000101539,0.99825114,0.00006560191,0.000044523535,0.000006756777],"study_design_scores_gemma":[0.0003490772,0.00011960353,0.007415143,0.00018484826,0.00006911158,1.1554681e-7,0.000035962483,0.00010732205,0.98962563,0.0000018021271,0.0014570494,0.00063432625],"about_ca_topic_score_codex":0.000064257394,"about_ca_topic_score_gemma":0.00007528313,"teacher_disagreement_score":0.008625499,"about_ca_system_score_codex":0.000072701245,"about_ca_system_score_gemma":0.00041697078,"threshold_uncertainty_score":0.9997817},"labels":[],"label_agreement":null},{"id":"W3215264342","doi":"10.1101/2021.11.24.469908","title":"Expression of mini-G proteins specifically halt cognate GPCR trafficking and intracellular signalling","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Daiichi Sankyo Europe; Japan Society for the Promotion of Science; Leibniz-Gemeinschaft; Medical Research Council; Daiichi Sankyo Foundation of Life Science; Imperial College London; Japan Agency for Medical Research and Development; Uehara Memorial Foundation; National Institute for Health and Care Research; NIHR Imperial Biomedical Research Centre; Biotechnology and Biological Sciences Research Council; Tokyo Biochemical Research Foundation; Society for Endocrinology; Diabetes UK; Eli Lilly and Company","keywords":"G protein-coupled receptor; Signalling; Receptor; Endosome; Biology; Intracellular; G protein; Cell biology; G protein-coupled receptor kinase; Signal transduction; Cell signaling; Computational biology; Biochemistry","score_opus":0.011985280812699511,"score_gpt":0.20605931268420635,"score_spread":0.19407403187150685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215264342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9592316,0.0062158722,0.033319674,0.00003600736,0.00046172884,0.00061572273,0.000059424197,0.000054559627,0.000005368764],"genre_scores_gemma":[0.97195387,0.0010702243,0.026212117,0.000047607446,0.00051303045,0.000067752204,0.0000035863088,0.00012587897,0.000005924724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970371,0.00020059073,0.0007083994,0.0012101878,0.00037503842,0.00046865127],"domain_scores_gemma":[0.99789083,0.00002708948,0.0005404691,0.0007971259,0.000499784,0.00024471103],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006404657,0.00054020644,0.0006393881,0.00012782098,0.0001370824,0.00018259294,0.00040702362,0.00084542105,0.00007568048],"category_scores_gemma":[0.00017649312,0.0005755979,0.00021507649,0.00016256943,0.00011796758,0.000012422944,0.00060823414,0.0005530975,0.0000020330076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005908661,0.00012227402,0.00029405544,0.00045121106,0.00010429455,0.00004267622,0.00002293634,0.0003260011,0.99846977,0.000071299095,0.00002668048,0.000009699545],"study_design_scores_gemma":[0.00042401065,0.00012237953,0.0005982026,0.00094252947,0.000070848524,6.42219e-8,0.00002219297,0.0003531083,0.9959406,0.0000014079064,0.00091139425,0.0006132361],"about_ca_topic_score_codex":0.000011959326,"about_ca_topic_score_gemma":0.0000018125197,"teacher_disagreement_score":0.012722236,"about_ca_system_score_codex":0.000029618657,"about_ca_system_score_gemma":0.00038442356,"threshold_uncertainty_score":0.99966955},"labels":[],"label_agreement":null},{"id":"W3215378435","doi":"10.1007/978-3-030-78799-8_2","title":"Adrenergic Receptor Signaling Pathways in the Regulation of Apoptosis and Autophagy in the Heart","year":2021,"lang":"en","type":"book-chapter","venue":"Advances in biochemistry in health and disease","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Autophagy; Apoptosis; β2 adrenergic receptor; Adrenergic; Adrenergic receptor; Cell biology; Signal transduction; Receptor; Biology; Chemistry; Internal medicine; Endocrinology; Medicine; Biochemistry","score_opus":0.012251599694397793,"score_gpt":0.2589911345469735,"score_spread":0.2467395348525757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215378435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82960445,0.16726702,0.000027098333,0.00071024377,0.00010812499,0.0005363703,0.00010171223,0.0000040736277,0.0016409312],"genre_scores_gemma":[0.97892135,0.01876507,0.00027981898,0.0009923981,0.00012892035,0.00006058795,0.00047107306,0.000018428373,0.00036234435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984554,0.000112252055,0.0005427173,0.00046684314,0.00018339312,0.00023939373],"domain_scores_gemma":[0.9992732,0.00008188293,0.00019186475,0.0002979052,0.000027477625,0.00012771286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005637911,0.0002246943,0.00029797497,0.00006686273,0.000046106983,0.000019076799,0.00015700374,0.00020508903,0.000025924388],"category_scores_gemma":[0.00013916867,0.0001752523,0.000059375478,0.000083940744,0.000096406824,0.00000895046,0.000054225435,0.00023739172,1.5076901e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018194853,0.00065740116,0.008883745,0.009770635,0.000039722527,0.000057431214,0.0025524013,0.0028608714,0.91939205,0.024146596,0.00056269014,0.029256996],"study_design_scores_gemma":[0.0086751,0.0015617575,0.0036119372,0.013803467,0.00009218449,0.00007080054,0.010260623,0.0010432169,0.7793536,0.07195132,0.10605489,0.003521066],"about_ca_topic_score_codex":0.000033970497,"about_ca_topic_score_gemma":0.000028034996,"teacher_disagreement_score":0.14931694,"about_ca_system_score_codex":0.00003094725,"about_ca_system_score_gemma":0.00029594262,"threshold_uncertainty_score":0.7146581},"labels":[],"label_agreement":null},{"id":"W3215388564","doi":"10.1038/s41467-022-34382-7","title":"Computationally designed GPCR quaternary structures bias signaling pathway activation","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; Université de Montréal; Fondation pour la Recherche Médicale; Swiss Cancer Research Foundation; European Commission; École Polytechnique Fédérale de Lausanne; Fonds Wetenschappelijk Onderzoek; Ludwig Institute for Cancer Research; Fonds De La Recherche Scientifique - FNRS; Fonds National de la Recherche Luxembourg; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Novartis Foundation; Canadian Institutes of Health Research; National Science Foundation","keywords":"Protein quaternary structure; G protein-coupled receptor; Receptor; Signal transduction; Chemokine receptor; Cell biology; Biology; Chemistry; Chemokine; Biochemistry","score_opus":0.03080449267150433,"score_gpt":0.2849695401246607,"score_spread":0.2541650474531564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3215388564","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.969884,0.0034721217,0.023230927,0.0014528969,0.0003581428,0.00043991164,0.00010923969,0.000071331524,0.0009814549],"genre_scores_gemma":[0.9796193,0.000038119244,0.017150296,0.0008827196,0.00010555538,0.00007726605,0.0019611912,0.000024702977,0.00014083073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998868,0.00032370936,0.00020805425,0.00022518406,0.00023461197,0.00014043857],"domain_scores_gemma":[0.99887127,0.00008877752,0.00014887576,0.00070906867,0.00013753233,0.000044497996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003138666,0.00012293771,0.000098775214,0.00007199172,0.0007618085,0.000039093433,0.00077958993,0.00014340579,0.00017380471],"category_scores_gemma":[0.00008164468,0.00012892298,0.00007574281,0.00016015195,0.000038123988,0.0000071842096,0.00047169297,0.00049762946,0.0000029352752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036343143,0.00006254342,0.00033315967,0.0000031772554,0.000047355978,5.160523e-7,0.00013898201,0.0068382574,0.9797403,0.010051637,0.001311494,0.0014361859],"study_design_scores_gemma":[0.0007666547,0.00034463283,0.0013989216,0.000012892211,0.000028049226,0.000031781405,0.0008598755,0.004195416,0.80737805,0.0050733387,0.17937733,0.00053306547],"about_ca_topic_score_codex":0.000015398458,"about_ca_topic_score_gemma":0.000011529145,"teacher_disagreement_score":0.17806584,"about_ca_system_score_codex":0.000039163777,"about_ca_system_score_gemma":0.00012019877,"threshold_uncertainty_score":0.5859292},"labels":[],"label_agreement":null},{"id":"W3216356670","doi":"10.1111/bph.15750","title":"A positive allosteric modulator for the muscarinic receptor (M1 mAChR) improves pathology and cognitive deficits in female <scp>APPswe</scp>/PSEN1ΔE9 mice","year":2021,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Brain Institute; University of Ottawa","funders":"Krembil Foundation; Canadian Institutes of Health Research; Alberta Innovates - Health Solutions","keywords":"Morris water navigation task; Allosteric modulator; Hippocampus; Agonist; Muscarinic acetylcholine receptor; Neuroscience; Water maze; Cognitive decline; Endocrinology; ADAM10; Receptor; Pharmacology; Internal medicine; Medicine; Chemistry; Psychology; Dementia; Disease","score_opus":0.010296621745642075,"score_gpt":0.2643594516189588,"score_spread":0.25406282987331674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3216356670","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9751319,0.020704094,0.0026076415,0.00019457717,0.0008547719,0.00034592915,0.00010999004,0.0000033313054,0.000047744503],"genre_scores_gemma":[0.9927687,0.0039978893,0.001081679,0.0012366836,0.00058717653,0.000044405795,0.00004452306,0.000033099095,0.00020585538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984077,0.00030890206,0.00045917273,0.00034986195,0.000103860846,0.00037050073],"domain_scores_gemma":[0.9987174,0.00038544816,0.0003078419,0.000056187342,0.00043440072,0.00009868772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005261149,0.00017436942,0.0003513893,0.00006104696,0.00013112498,0.000053828706,0.00018111401,0.00021477015,0.000053081945],"category_scores_gemma":[0.000360863,0.00017490497,0.00017046925,0.000112243535,0.00012511465,0.000014920965,0.0001497621,0.00031142644,0.0000015759887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014634579,0.0001301125,0.0001357342,0.000029159393,0.00024179039,0.00044104975,0.00020111536,0.000024599742,0.9749139,0.000012080562,0.0010245618,0.022699546],"study_design_scores_gemma":[0.0038176973,0.0009801567,0.0026956785,0.00009991946,0.0002506033,0.007292728,0.0016702275,0.0002082789,0.97930735,0.00009117863,0.0034481357,0.0001380575],"about_ca_topic_score_codex":0.000015684493,"about_ca_topic_score_gemma":0.00004445364,"teacher_disagreement_score":0.022561489,"about_ca_system_score_codex":0.00002132535,"about_ca_system_score_gemma":0.00017836299,"threshold_uncertainty_score":0.71324176},"labels":[],"label_agreement":null},{"id":"W326264078","doi":"10.1016/b978-0-12-374203-2.00154-8","title":"Photoresponse in Squid","year":2010,"lang":"en","type":"book-chapter","venue":"Elsevier eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Rhodopsin; Squid; Arrestin; Depolarization; Visual phototransduction; Biophysics; Phospholipase C; Membrane; Cell biology; Biology; Chemistry; Biochemistry; Retinal; Signal transduction; G protein-coupled receptor","score_opus":0.008374435802227813,"score_gpt":0.22756723284643016,"score_spread":0.21919279704420233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W326264078","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010575207,0.0010436097,0.00001360057,0.000014633115,0.000546811,0.00034712756,0.000028150029,0.000014164296,0.9874167],"genre_scores_gemma":[0.007946106,0.00014782257,0.00067826675,0.0003134638,0.0005669027,0.00003148994,0.0000863529,0.00010242716,0.99012715],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.998732,0.000026036489,0.0003208128,0.00049506477,0.00016581512,0.00026031976],"domain_scores_gemma":[0.99918175,0.000011823925,0.0001294874,0.00052383024,0.000053006406,0.00010008319],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002980811,0.00033506515,0.0003122265,0.000104828905,0.000049059396,0.000025546067,0.000265693,0.00082311704,0.00071989547],"category_scores_gemma":[0.00002591459,0.0003284067,0.00021079154,0.000005928304,0.00007692056,9.406053e-7,0.00013585755,0.00048190594,0.00008004952],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010605453,0.0000064917085,0.0000027594701,0.00001831403,0.00003233445,0.00002755362,0.00003578395,4.097078e-7,0.6884421,0.0006713902,0.000059517453,0.31059727],"study_design_scores_gemma":[0.00023546856,0.00011099672,0.0000027177823,0.000075160926,0.0000148664785,0.00001445797,0.0000026001414,9.991707e-7,0.16758087,0.0019056713,0.82973045,0.0003257266],"about_ca_topic_score_codex":6.691972e-7,"about_ca_topic_score_gemma":0.00007402472,"teacher_disagreement_score":0.82967097,"about_ca_system_score_codex":0.000018689485,"about_ca_system_score_gemma":0.00013618122,"threshold_uncertainty_score":0.9999168},"labels":[],"label_agreement":null},{"id":"W33610701","doi":"10.1007/978-3-642-41199-1_21","title":"Arrestins as Regulatory Hubs in Cancer Signalling Pathways","year":2013,"lang":"en","type":"article","venue":"Handbook of experimental pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"","keywords":"Endocytosis; Signalling; Biology; Scaffold protein; G protein-coupled receptor; Cancer; Cell biology; Function (biology); Signal transduction; Neuroscience; Receptor; Signal transducing adaptor protein; Genetics","score_opus":0.019074046283981686,"score_gpt":0.29899585647511956,"score_spread":0.2799218101911379,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W33610701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986028,0.012108157,0.00019260148,0.000026551663,0.00045575845,0.00033005004,0.000004337787,0.0000099800545,0.0008445638],"genre_scores_gemma":[0.99781835,0.0003841314,0.00060690736,0.00045914922,0.00024232405,0.00023256645,0.00001700689,0.00002468117,0.00021485647],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897003,0.000068290734,0.00027819196,0.00030322044,0.000105212486,0.00027503917],"domain_scores_gemma":[0.999641,0.000012847862,0.000101913945,0.000107870226,0.000044043903,0.00009232396],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009481092,0.00015872376,0.00019751771,0.00006050556,0.000044897086,0.000008438191,0.00016476928,0.00013211794,0.004433086],"category_scores_gemma":[0.0000056650297,0.00015908292,0.00007700613,0.00004920592,0.00009088447,0.000008351953,0.0000953868,0.000091567344,0.000029830164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008089717,0.00015259424,0.00025512456,0.000009031605,0.00003594643,0.000004586018,0.00021560513,0.00022168111,0.99701405,0.00007098064,0.0014365051,0.000503],"study_design_scores_gemma":[0.001033671,0.00034586462,0.000066048146,0.00004264408,0.000008145726,0.0000048806482,0.00027122998,0.0002004514,0.99677217,0.000108520115,0.0009764789,0.00016992041],"about_ca_topic_score_codex":0.00024149065,"about_ca_topic_score_gemma":0.0000072835423,"teacher_disagreement_score":0.011790378,"about_ca_system_score_codex":0.0000350551,"about_ca_system_score_gemma":0.000080973405,"threshold_uncertainty_score":0.996477},"labels":[],"label_agreement":null},{"id":"W339729937","doi":"10.1139/y09-089","title":"Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of G<sub>i</sub> protein and proliferation in A10 vascular smooth muscle cellsThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research.","year":2009,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Angiotensin II; Vascular smooth muscle; Endocrinology; Internal medicine; Epidermal growth factor; Epidermal growth factor receptor; Transactivation; Chemistry; Signal transduction; Phosphorylation; Angiotensin receptor; Receptor; Biology; Cell biology; Biochemistry; Gene expression; Medicine","score_opus":0.00972997631946989,"score_gpt":0.24677649802839788,"score_spread":0.23704652170892798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W339729937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99880195,0.00056876655,0.000057798643,0.00013789136,0.000066059205,0.00035321355,0.0000073816786,4.0403592e-7,0.0000065328677],"genre_scores_gemma":[0.9993419,0.00040228385,0.00007167249,0.000028398465,0.00013615466,0.0000075289195,0.0000068649024,0.0000048513907,3.660643e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998492,0.00052791636,0.00048750392,0.0001876701,0.00010522306,0.00019966878],"domain_scores_gemma":[0.99935895,0.000032013457,0.0002257472,0.00005509832,0.0002591435,0.00006904547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007477047,0.00009103628,0.00040894697,0.00041472598,0.00002790233,0.0000021212884,0.00005774445,0.00021140043,0.0001134939],"category_scores_gemma":[0.00012959907,0.00009055591,0.000068794136,0.00027522194,0.00008417091,0.00004286292,0.000006012808,0.0002419955,3.0400642e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007969113,0.00012917591,0.00042888176,0.000052834806,0.000024066707,0.0000015744678,0.00076307624,0.00058754295,0.9921901,0.000011293954,0.0000071013856,0.005007443],"study_design_scores_gemma":[0.002084433,0.0013562414,0.025351899,0.000121990444,0.000009315106,7.34582e-7,0.00007753389,0.00006850326,0.9705403,0.00028168136,0.000040879397,0.00006652635],"about_ca_topic_score_codex":0.0002800643,"about_ca_topic_score_gemma":0.0009848777,"teacher_disagreement_score":0.024923017,"about_ca_system_score_codex":0.000049401602,"about_ca_system_score_gemma":0.00020948594,"threshold_uncertainty_score":0.36927631},"labels":[],"label_agreement":null},{"id":"W392936092","doi":"10.1007/978-1-61779-160-4","title":"Signal Transduction Protocols","year":2011,"lang":"en","type":"book","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Robarts Research Institute; National Institutes of Health; Université de Montréal; Medical School, University of Michigan; Université de Montpellier; Université Paris Descartes; University of Toronto; McGill University Health Centre; McGill University; Hotchkiss Brain Institute, University of Calgary; Johns Hopkins University; Leslie Dan Faculty of Pharmacy, University of Toronto; University of Michigan","keywords":"Signal transduction; Computer science; Cell biology; Biology","score_opus":0.03687157559085965,"score_gpt":0.38027982482041095,"score_spread":0.3434082492295513,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W392936092","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006629511,0.0011617821,0.92880976,0.000015112995,0.0003562768,0.0042692083,0.000024185629,0.000024569352,0.065272816],"genre_scores_gemma":[0.000047831083,0.00016005403,0.87147707,0.0003782183,0.00064539415,0.00441902,0.00070094556,0.00019260918,0.12197886],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968167,0.0010090225,0.0005982654,0.0009852832,0.00010642636,0.00048432086],"domain_scores_gemma":[0.9989039,0.00002643602,0.00025465345,0.0006225243,0.00009361723,0.000098871686],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013451754,0.000498701,0.0006222067,0.00022388474,0.000047112644,0.000016421815,0.00049629604,0.0016415854,0.0011510121],"category_scores_gemma":[0.00007822589,0.00049398525,0.0003546814,0.00008463761,0.00016755673,0.0000020517814,0.0001417099,0.00054388493,0.000018383756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009836122,0.000044717046,0.000009219339,0.000053901796,0.000091800466,0.000016405404,0.000031181273,0.000014043921,0.9678319,0.004967996,0.00050546334,0.026334992],"study_design_scores_gemma":[0.00034931794,0.0005574921,0.000001078248,0.00006221453,0.000025977872,0.00002254781,0.000004508245,0.000009685492,0.6523446,0.02996288,0.3162446,0.0004151128],"about_ca_topic_score_codex":0.000011048057,"about_ca_topic_score_gemma":0.0000072720964,"teacher_disagreement_score":0.31573915,"about_ca_system_score_codex":0.00005821486,"about_ca_system_score_gemma":0.0003243772,"threshold_uncertainty_score":0.99976206},"labels":[],"label_agreement":null},{"id":"W4200140974","doi":"10.1073/pnas.2113373118","title":"Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled receptors expressed in tumors","year":2021,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of General Medical Sciences; National Institute on Aging; Welch Foundation","keywords":"G protein-coupled receptor; Biology; Effector; Receptor; Genetics; Computational biology; Mutation; Signal transduction; Phenotype; Gene; Cell biology","score_opus":0.019762027609673046,"score_gpt":0.2964087792612141,"score_spread":0.27664675165154107,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200140974","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986837,0.00013949939,0.0000012698584,0.00070767786,0.000023514342,0.00019180903,0.000032150645,0.000002401015,0.00021798852],"genre_scores_gemma":[0.998847,0.000015543055,0.00094625395,0.000044640525,0.00003444367,0.000026738811,0.000005808632,0.000004248147,0.00007529311],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988418,0.000015407322,0.00030287658,0.0002553831,0.00043294491,0.00015154245],"domain_scores_gemma":[0.9995049,0.000020975798,0.00022636827,0.000009853808,0.0002075936,0.000030308976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045307388,0.000090101086,0.00012946164,0.000114575356,0.00010914976,0.000017795459,0.00028310672,0.00008471917,0.000055159722],"category_scores_gemma":[0.00034179658,0.000066632,0.00007359435,0.0005684518,0.00019730498,0.000026146829,0.00012214718,0.000115093884,3.5721413e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002694968,0.000027084305,0.0015650664,0.000016651082,0.0000073281926,2.2771204e-8,0.000089958055,0.00094735326,0.9931497,0.004062972,0.00003881807,0.000068124864],"study_design_scores_gemma":[0.00028389753,0.00006583192,0.016175365,0.00011999553,0.0000033848514,0.00000532233,0.00015475329,0.0012535001,0.9698745,0.011960229,0.000022136566,0.00008106817],"about_ca_topic_score_codex":0.000017814538,"about_ca_topic_score_gemma":0.000002447772,"teacher_disagreement_score":0.023275156,"about_ca_system_score_codex":0.00005565546,"about_ca_system_score_gemma":0.00008140424,"threshold_uncertainty_score":0.2717174},"labels":[],"label_agreement":null},{"id":"W4200450249","doi":"10.1093/cercor/bhab406","title":"Developmental age and biological sex influence muscarinic receptor function and neuron morphology within layer VI of the medial prefrontal cortex","year":2021,"lang":"en","type":"article","venue":"Cerebral Cortex","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Neuroscience; Muscarinic acetylcholine receptor; Prefrontal cortex; Dendrite (mathematics); Neuron; Nicotinic agonist; Acetylcholine; Electrophysiology; Biology; Apical dendrite; Nicotinic acetylcholine receptor; Psychology; Endocrinology; Receptor; Cerebral cortex; Cognition","score_opus":0.014888642257030793,"score_gpt":0.22068919556564492,"score_spread":0.20580055330861413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4200450249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99898523,0.00027624407,0.000087125576,0.000030137202,0.00034575447,0.00013203993,0.000015522764,0.00001096622,0.00011696136],"genre_scores_gemma":[0.998662,0.000087181215,0.00054400513,0.00031777166,0.00009209695,0.0000086332275,0.000057355952,0.000015477866,0.00021546948],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99897987,0.00010848735,0.00023486397,0.00040303095,0.000101200574,0.00017255082],"domain_scores_gemma":[0.9996345,0.000014647746,0.00010206783,0.00013028277,0.000047064408,0.000071452014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011272756,0.00014751079,0.00017615648,0.000015192173,0.00009276347,0.000018580473,0.00010345634,0.00019687208,0.00011377274],"category_scores_gemma":[0.0000740557,0.00010824888,0.000051234834,0.00006092599,0.0001831024,0.0000070263086,0.00028661787,0.00013663458,0.0000024125409],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007490861,0.000022586548,0.028527226,0.000008973831,0.00002478809,0.000005709802,0.000082825216,0.0000028765846,0.9702819,0.000106105756,0.000057692498,0.0008043973],"study_design_scores_gemma":[0.0005679669,0.00035288194,0.58397734,0.000012529154,0.000018999357,0.00009682143,0.00024656858,0.00001948036,0.41373175,0.00016528003,0.0006533098,0.0001570891],"about_ca_topic_score_codex":0.000018163428,"about_ca_topic_score_gemma":0.000055874243,"teacher_disagreement_score":0.55655015,"about_ca_system_score_codex":0.0000102249105,"about_ca_system_score_gemma":0.0000812026,"threshold_uncertainty_score":0.44142613},"labels":[],"label_agreement":null},{"id":"W4205130951","doi":"10.1016/j.colsurfb.2021.112315","title":"Farnesylation and lipid unsaturation are critical for the membrane binding of the C-terminal segment of G-Protein Receptor Kinase 1","year":2022,"lang":"en","type":"article","venue":"Colloids and Surfaces B Biointerfaces","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Prenylation; Palmitoylation; Myristoylation; Rhodopsin; G protein-coupled receptor; Biochemistry; Peripheral membrane protein; G protein; Membrane protein; Visual phototransduction; Biology; Cell biology; Biophysics; Chemistry; Membrane; Receptor; Integral membrane protein; Retinal; Enzyme","score_opus":0.012628994440153257,"score_gpt":0.24230802402068988,"score_spread":0.22967902958053663,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205130951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961068,0.0017394957,0.0008743859,0.0004818178,0.00025250702,0.00040732368,0.00012347374,0.0000028029574,0.000011374746],"genre_scores_gemma":[0.9987357,0.00013923865,0.00070539024,0.000020506906,0.000036366713,0.000043061624,0.000018532555,0.000008916078,0.00029224897],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992704,0.000089528585,0.00020668787,0.00019316356,0.0001312893,0.00010897486],"domain_scores_gemma":[0.99956787,0.000063870044,0.00014426149,0.000132547,0.00006737418,0.00002410956],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003610143,0.00009929369,0.00013580664,0.000021098012,0.00031556285,0.000028209315,0.00012339505,0.00004687424,0.00003914519],"category_scores_gemma":[0.00007863806,0.00006331908,0.00006014568,0.00006976643,0.00013281108,0.000006569322,0.00015654926,0.000061118226,6.625065e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016192129,0.00002326461,0.0006094497,0.000080657934,0.000025610812,8.066544e-8,0.00015760896,0.00021390001,0.9974135,0.00017108495,0.000051738854,0.001091145],"study_design_scores_gemma":[0.0003092278,0.00045827852,0.0002513069,0.000046110097,0.000027471622,0.000004520346,0.002238318,0.001961764,0.99085116,0.000023131293,0.0037386497,0.00009003047],"about_ca_topic_score_codex":0.000019484733,"about_ca_topic_score_gemma":0.000012331753,"teacher_disagreement_score":0.006562346,"about_ca_system_score_codex":0.000008323175,"about_ca_system_score_gemma":0.000024416007,"threshold_uncertainty_score":0.25820774},"labels":[],"label_agreement":null},{"id":"W4205215804","doi":"10.3389/fncel.2021.806618","title":"The Signaling and Pharmacology of the Dopamine D1 Receptor","year":2022,"lang":"en","type":"review","venue":"Frontiers in Cellular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Weston Brain Institute; McGill University","keywords":"Dopamine receptor; Dopamine; Pharmacology; Dopamine receptor D1; Neuroscience; Dopamine receptor D2; Dopamine receptor D3; Medicine; Psychology","score_opus":0.023404583252127673,"score_gpt":0.27026780043248383,"score_spread":0.24686321718035614,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205215804","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010153761,0.9914696,0.0009976221,0.00002375088,0.005942959,0.0004818389,0.000020484236,0.0000036020185,0.000044721346],"genre_scores_gemma":[0.00039434523,0.99836266,0.00030461754,0.00007344589,0.00013935573,0.00006151792,0.000011978814,0.000028856883,0.0006232457],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980305,0.00047720797,0.00041463342,0.0005312315,0.00024088033,0.00030558938],"domain_scores_gemma":[0.9991664,0.000057007233,0.00033801983,0.00037350843,0.00001615541,0.000048879985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007497922,0.00023167462,0.00045285944,0.00006393906,0.0003454581,0.00003160271,0.0010021706,0.00012936353,0.000032491156],"category_scores_gemma":[0.0001319373,0.00014229161,0.0002106133,0.00037656722,0.00037613936,0.0000034377872,0.0005641687,0.00036513456,2.9020416e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000017244849,0.000044834098,0.00003112926,0.0008868434,0.000024917183,0.0000070558967,0.000031883694,0.000069746166,0.6564296,0.000040354018,0.0033405162,0.33907586],"study_design_scores_gemma":[0.000084208084,0.000079682635,3.0521227e-7,0.00011565669,0.00004795581,0.000008560729,0.000034406017,0.00006920768,0.056473736,0.00001491572,0.9429276,0.00014378014],"about_ca_topic_score_codex":0.000003216353,"about_ca_topic_score_gemma":5.544271e-7,"teacher_disagreement_score":0.93958706,"about_ca_system_score_codex":0.00002731161,"about_ca_system_score_gemma":0.00017861357,"threshold_uncertainty_score":0.5802483},"labels":[],"label_agreement":null},{"id":"W4205285244","doi":"10.1016/s0735-1097(01)96025-5","title":"Early onset of QT interval prolongation and IKr downregulation in rabbits with compensated complete heart block Fumiaki Suto, Sean A. Cahill, Ilana Greenwald, Gil J. Gross. Hospital for Sick Children, Toronto, ON, Canada","year":2001,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; QT interval; Prolongation; Block (permutation group theory); Interval (graph theory); Internal medicine; Pediatrics; Combinatorics","score_opus":0.005677229573203105,"score_gpt":0.2091826340304896,"score_spread":0.2035054044572865,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205285244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984666,0.00020086233,0.00026428816,0.0004510527,0.00010717053,0.0003285468,0.00015373841,0.0000012659926,0.000026446867],"genre_scores_gemma":[0.99924976,0.00004251407,0.0004076223,0.00010443519,0.00013886463,0.0000042624765,0.000017750546,0.0000138613195,0.000020951918],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99887884,0.00019724229,0.0004155468,0.00016072398,0.00017206559,0.00017558222],"domain_scores_gemma":[0.998827,0.00004811745,0.00063046097,0.00016832826,0.00027146126,0.000054673535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030080488,0.00013761884,0.00054627564,0.00004135533,0.00005224263,0.000004308976,0.00016513524,0.00005833564,0.0000022102438],"category_scores_gemma":[0.0000507314,0.00009815584,0.0001239953,0.00010165804,0.00020224546,0.000008875,0.000039453098,0.00010147309,2.8651256e-8],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01001342,0.00016898998,0.602745,0.00005158006,0.0014661485,0.00006869199,0.00021699612,0.0138191525,0.36286297,0.00020958041,0.006867257,0.0015102106],"study_design_scores_gemma":[0.0029586933,0.008365633,0.9545463,0.00009467448,0.00010279327,0.0011566301,0.00042614315,0.00025478803,0.029801365,0.000051373565,0.0019853662,0.0002562619],"about_ca_topic_score_codex":0.012024093,"about_ca_topic_score_gemma":0.02844964,"teacher_disagreement_score":0.3518013,"about_ca_system_score_codex":0.00006757718,"about_ca_system_score_gemma":0.0002283521,"threshold_uncertainty_score":0.99455494},"labels":[],"label_agreement":null},{"id":"W4205615486","doi":"10.1371/journal.pone.0165770","title":"Correction: Structure-Activity Relationship Studies of N- and C-Terminally Modified Secretin Analogs for the Human Secretin Receptor","year":2016,"lang":"en","type":"erratum","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Population and Public Health; Hong Kong Government; King Saud University","keywords":"Secretin; Correct name; Chemistry; Bioinformatics; Computational biology; Medicine; Biochemistry; Biology; Pancreas","score_opus":0.06932366439704521,"score_gpt":0.2924750647155953,"score_spread":0.2231514003185501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205615486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9745776,0.010353935,0.0039683525,0.0004191449,0.0066187484,0.0016954193,0.00083803904,0.000036885154,0.0014918986],"genre_scores_gemma":[0.90102047,0.0024533519,0.0008027571,0.000056672987,0.0030303558,0.00016279666,0.0008007536,0.00008508477,0.09158776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985795,0.00013224737,0.0003306365,0.00048485253,0.0002446442,0.00022812054],"domain_scores_gemma":[0.9985161,0.00021754907,0.00044929946,0.00040897485,0.00035160797,0.000056511002],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003503795,0.00029834764,0.0005037993,0.00006034066,0.00032872593,0.000028112237,0.00021366049,0.0005434147,0.00007452974],"category_scores_gemma":[0.0005919478,0.00020772371,0.00013871332,0.000059965576,0.00019058198,0.0000050085278,0.00012706696,0.0003421833,7.995707e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014971524,0.0000855935,0.0002541467,0.00042548648,0.0009289122,2.8213134e-7,0.00012263513,0.0000033475085,0.92004824,0.00014789587,0.07719393,0.00063984183],"study_design_scores_gemma":[0.0012199365,0.001715132,0.0015470131,0.001738082,0.0011873671,0.0000053511553,0.0003725703,0.00045096048,0.9672796,0.0020458126,0.021480553,0.00095758226],"about_ca_topic_score_codex":0.000014485922,"about_ca_topic_score_gemma":0.00006434719,"teacher_disagreement_score":0.09009586,"about_ca_system_score_codex":0.000029111825,"about_ca_system_score_gemma":0.00009588258,"threshold_uncertainty_score":0.8470727},"labels":[],"label_agreement":null},{"id":"W4205755044","doi":"","title":"Functional dissociation of behavioral effects from acetylcholine and glutamate released from cholinergic striatal interneurons","year":2022,"lang":"en","type":"article","venue":"Scholarship@Western (Western University)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Western University","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund; Weston Brain Institute; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Vesicular acetylcholine transporter; Acetylcholine; Cholinergic; Dopaminergic; Neuroscience; Dopamine; Glutamate receptor; Chemistry; Striatum; Glutamatergic; Pharmacology; Neurotransmitter; Biology; Biochemistry; Choline acetyltransferase; Central nervous system; Receptor","score_opus":0.04181406274209222,"score_gpt":0.27992218051136175,"score_spread":0.23810811776926954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205755044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974773,0.00017460194,0.001128213,0.00003521107,0.00037771938,0.00017722609,0.0005986866,0.000025833942,0.0000052265095],"genre_scores_gemma":[0.997711,0.000047709495,0.000057748348,0.00007629741,0.00014512459,0.000003006994,0.0013818772,0.000030754516,0.0005464772],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99851334,0.00027828506,0.00021240942,0.0005029486,0.00028103008,0.00021198567],"domain_scores_gemma":[0.9992631,0.00004359687,0.000226356,0.0002810511,0.00006124197,0.00012463165],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00014263991,0.00020497425,0.00023530511,0.000119873024,0.00019788767,0.000052009364,0.00029254425,0.00013217173,0.00010149236],"category_scores_gemma":[0.000020456304,0.00024553644,0.0001255143,0.00013313131,0.00004835142,0.000052177125,0.0005338387,0.00030985905,0.0000048495995],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003514562,0.00012455352,0.4649597,0.000007706654,0.00007311266,0.00001797002,0.00010035581,0.00011273384,0.5340007,0.000007409168,0.0000018100919,0.00024247925],"study_design_scores_gemma":[0.0029916503,0.00051415944,0.67679304,0.00003671991,0.00017045811,0.0000054317406,0.0003405701,0.0000047223966,0.31815997,0.00006464034,0.0005800613,0.0003385695],"about_ca_topic_score_codex":0.000055660403,"about_ca_topic_score_gemma":0.00025112805,"teacher_disagreement_score":0.21584073,"about_ca_system_score_codex":0.00006559286,"about_ca_system_score_gemma":0.000051548916,"threshold_uncertainty_score":0.9999997},"labels":[],"label_agreement":null},{"id":"W4205871026","doi":"10.1101/2022.01.11.475811","title":"Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Science and Engineering Research Board; The Wellcome Trust DBT India Alliance; Council of Scientific and Industrial Research, India; Department of Biotechnology, Ministry of Science and Technology, India; Indian Institute of Technology Kanpur; Wellcome Trust","keywords":"G protein-coupled receptor; Endosome; Arrestin; Internalization; Cell biology; Allosteric regulation; Phosphorylation; Receptor; Agonist; Biology; Effector; Signal transduction; Chemistry; Biochemistry","score_opus":0.011159378977291926,"score_gpt":0.21496642982907913,"score_spread":0.20380705085178719,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205871026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99531347,0.0015168051,0.0021725374,0.000029139339,0.00039116514,0.0004581242,0.00007843267,0.00003667794,0.0000036245606],"genre_scores_gemma":[0.9975182,0.00022226418,0.001896629,0.000040632123,0.00013087985,0.00009275842,0.0000031900008,0.00009378433,0.00000166676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99774855,0.0001976503,0.00055590284,0.00087602146,0.00026596108,0.0003558905],"domain_scores_gemma":[0.9987965,0.000027203887,0.00039236498,0.00056060374,0.000114536146,0.000108744935],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00058880326,0.00038379076,0.00045005447,0.00017540409,0.00009110314,0.000065715416,0.00031170217,0.00039662753,0.00005276277],"category_scores_gemma":[0.00012951496,0.0004542965,0.00010560809,0.00021211698,0.00004787674,0.000008473496,0.0004274953,0.00041988934,7.64189e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004646555,0.00008017361,0.0012363298,0.00018179714,0.00005731786,0.0000076967235,0.000015551905,0.0013627072,0.99693465,0.000047692825,0.000015617434,0.000014005697],"study_design_scores_gemma":[0.0003971451,0.0001410076,0.0034117368,0.00021835821,0.00004257129,3.626118e-8,0.000010470103,0.002381084,0.9926074,0.0000025994268,0.0002900541,0.0004975491],"about_ca_topic_score_codex":0.000059026086,"about_ca_topic_score_gemma":0.0000020408058,"teacher_disagreement_score":0.004327256,"about_ca_system_score_codex":0.00005588105,"about_ca_system_score_gemma":0.00019339682,"threshold_uncertainty_score":0.9997909},"labels":[],"label_agreement":null},{"id":"W4206332366","doi":"10.3791/52387-v","title":"Operant Procedures for Assessing Behavioral Flexibility in Rats","year":2015,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cognitive flexibility; Prefrontal cortex; Neuroscience; Cognition; Flexibility (engineering); Psychology; Stimulus (psychology); Cognitive psychology; Executive functions; Task (project management); Computer science","score_opus":0.09408442398812819,"score_gpt":0.4889870486340391,"score_spread":0.39490262464591086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206332366","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99222404,0.0012250752,0.0059199347,0.000021618218,0.0003770899,0.00018351554,0.0000024198687,0.000002565786,0.00004372198],"genre_scores_gemma":[0.98771423,0.000020701946,0.011866217,0.00008946807,0.00020926583,0.000015203995,0.000010848833,0.000017515513,0.000056519213],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895847,0.00007579044,0.00043286153,0.00015767268,0.00019663319,0.00017854836],"domain_scores_gemma":[0.9993332,0.000006133494,0.00021000578,0.000102409685,0.00022473103,0.00012350743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067139365,0.00011533003,0.000225575,0.00005993494,0.000034012803,0.000055200067,0.00014439612,0.000096359785,0.0000173502],"category_scores_gemma":[0.00012378313,0.00009507838,0.00011214055,0.00004996431,0.000019904726,0.00001908384,0.00003800365,0.0000675086,5.926997e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048442464,0.0003205328,0.0007741371,0.000009702336,0.000018635772,0.000004954425,0.0004153374,0.000059630514,0.9968319,0.000017493754,0.0006467591,0.0004165],"study_design_scores_gemma":[0.0025875126,0.00074186164,0.00007590636,0.0000530254,0.000011031873,0.000021217555,0.001131839,0.00009441844,0.9932124,0.00013528514,0.0018166031,0.000118867196],"about_ca_topic_score_codex":0.000009191868,"about_ca_topic_score_gemma":0.0000021731528,"teacher_disagreement_score":0.005946282,"about_ca_system_score_codex":0.000049853687,"about_ca_system_score_gemma":0.00026801426,"threshold_uncertainty_score":0.38771838},"labels":[],"label_agreement":null},{"id":"W4206678587","doi":"10.3389/fphar.2021.803907","title":"3-OBA Is Not an Antagonist of GPR81","year":2022,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"","keywords":"Antagonist; Pharmacology; Medicine; Internal medicine; Receptor","score_opus":0.010517409427438203,"score_gpt":0.2737563955459822,"score_spread":0.26323898611854396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206678587","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99176353,0.00077599124,0.0034919032,0.0002320417,0.0030011518,0.00017319706,0.00008208142,0.000007674974,0.000472405],"genre_scores_gemma":[0.99385333,0.00015199982,0.0033886966,0.0018480957,0.00016651762,0.00005290288,0.00008267621,0.00001911415,0.0004366797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899155,0.00016188563,0.00021606211,0.00029440343,0.00010893816,0.00022713764],"domain_scores_gemma":[0.9996755,0.0000039620545,0.00008867275,0.00015199462,0.000025259002,0.000054578653],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000258513,0.00010312704,0.00018201476,0.00008829625,0.00009440489,0.0000041217745,0.00028646147,0.00007260386,0.0013317901],"category_scores_gemma":[0.000004749551,0.00011837166,0.00006447957,0.00010919233,0.000063376,0.000003237177,0.00016401264,0.00014862743,0.0000010915015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031874163,0.00012585535,0.0022003022,0.000007699269,0.000045334822,0.000008930675,0.00014632236,0.0004170186,0.9406447,0.000044501223,0.053214606,0.0028259957],"study_design_scores_gemma":[0.0008491618,0.0004761517,0.000109099274,7.615182e-7,0.000016357631,0.000008735551,0.0003933497,0.0008547134,0.84264004,0.00015551755,0.15437004,0.00012608664],"about_ca_topic_score_codex":0.000023178323,"about_ca_topic_score_gemma":0.0000018013432,"teacher_disagreement_score":0.10115544,"about_ca_system_score_codex":0.00003058589,"about_ca_system_score_gemma":0.00007028946,"threshold_uncertainty_score":0.9995811},"labels":[],"label_agreement":null},{"id":"W4206998699","doi":"10.3410/f.737434437.793581997","title":"Faculty Opinions recommendation of Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells.","year":2021,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"University of California, San Francisco; Searle Scholars Program; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"G protein-coupled receptor; Allosteric regulation; Receptor; Agonist; Chemistry; Biochemistry","score_opus":0.021070855013332057,"score_gpt":0.3085553484841743,"score_spread":0.28748449347084226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206998699","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00007253404,0.0038934415,0.000096030315,0.005937422,0.00032675458,0.0018458526,0.9878147,0.000004515414,0.0000087495955],"genre_scores_gemma":[0.0002005905,0.0014727827,0.0015602966,0.00018073445,0.00007483786,0.00033091212,0.9958565,0.000020397894,0.00030293938],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969928,0.00040645714,0.0012885361,0.0005326538,0.000561919,0.00021762357],"domain_scores_gemma":[0.99562484,0.000053210362,0.0012063577,0.00063199503,0.0023660676,0.00011754904],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001016362,0.00034844066,0.00077467377,0.0001833457,0.000060661394,0.000031160387,0.00056749815,0.00058855885,0.00010333765],"category_scores_gemma":[0.0024460277,0.00025557118,0.0003005625,0.00084860646,0.0001694831,0.000023286382,0.00034192795,0.00042857876,5.946127e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001549686,0.00035943906,0.000004301756,0.006360466,0.00012328418,5.298901e-8,0.00012744538,3.6489436e-7,0.015397779,0.000040135692,0.9760657,0.0015055572],"study_design_scores_gemma":[0.0003201989,0.00027062575,0.00006146335,0.009621883,0.000057118734,0.000003875953,0.000062581385,0.000004240385,0.08016976,0.000007753558,0.90921706,0.0002034626],"about_ca_topic_score_codex":0.000063841,"about_ca_topic_score_gemma":0.000007886483,"teacher_disagreement_score":0.066848636,"about_ca_system_score_codex":0.000046158922,"about_ca_system_score_gemma":0.00040787915,"threshold_uncertainty_score":0.9999896},"labels":[],"label_agreement":null},{"id":"W4207071725","doi":"10.3410/f.733437525.793581994","title":"Faculty Opinions recommendation of Structure of the µ-opioid receptor-Gi protein complex.","year":2021,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute of General Medical Sciences; Paul Scherrer Institut; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Heterotrimeric G protein; G protein-coupled receptor; DAMGO; Adenylyl cyclase; G protein; Agonist; Chemistry; Receptor; Gs alpha subunit; Opioid receptor; Gi alpha subunit; Helix (gastropod); Biology; Biochemistry","score_opus":0.024091087020805802,"score_gpt":0.321323361923086,"score_spread":0.2972322749022802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4207071725","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003057846,0.0013530354,0.00006717181,0.0321648,0.00090734323,0.0013324802,0.9641196,0.000007784958,0.000017193903],"genre_scores_gemma":[0.0001223842,0.00026067774,0.0014003784,0.0016689263,0.0003673262,0.000080958365,0.9953797,0.000027908685,0.0006917247],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960911,0.0005832264,0.0013709237,0.00062801526,0.0010468515,0.00027988382],"domain_scores_gemma":[0.99199986,0.00003167197,0.0017355083,0.0016468675,0.004432706,0.00015340553],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00066567014,0.0004564408,0.0007808755,0.00011270191,0.00019982192,0.00006431902,0.0016651656,0.0008513194,0.0010304522],"category_scores_gemma":[0.0032989748,0.00026852184,0.000762682,0.001086869,0.00030449167,0.000021904865,0.0007542387,0.00072683446,0.000004266051],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012974701,0.00016016273,0.0000029040352,0.0041011344,0.00015481652,3.755694e-8,0.000038945273,3.1951475e-7,0.013518233,0.00014641891,0.9811325,0.0007315178],"study_design_scores_gemma":[0.00038956467,0.00012305177,0.00018321411,0.005722851,0.00009652647,0.000012953869,0.000036440848,0.0000027905241,0.019611029,0.000029266226,0.97353256,0.00025976295],"about_ca_topic_score_codex":0.000035772217,"about_ca_topic_score_gemma":0.000007079374,"teacher_disagreement_score":0.031260103,"about_ca_system_score_codex":0.00004329298,"about_ca_system_score_gemma":0.0006215224,"threshold_uncertainty_score":0.9999767},"labels":[],"label_agreement":null},{"id":"W4210666168","doi":"10.1101/2022.01.26.477857","title":"An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Alliance for Research on Schizophrenia and Depression; McGill University; Tulane University; Brain and Behavior Research Foundation","keywords":"Neuroscience; Long-term potentiation; Synaptic plasticity; AMPA receptor; Postsynaptic potential; Biology; Neuroplasticity; Hippocampus; Metaplasticity; Synapse; Gating; Glutamate receptor; Receptor; Genetics","score_opus":0.009599172167674969,"score_gpt":0.2194814543655886,"score_spread":0.20988228219791363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210666168","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882415,0.00046371535,0.009637315,0.000024664076,0.00076379336,0.00051975274,0.00017854435,0.00015610385,0.000014626252],"genre_scores_gemma":[0.98787844,0.00010253895,0.010815505,0.00016434873,0.00063563616,0.00014813672,0.000007465199,0.00023222028,0.000015713382],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99669874,0.00024012003,0.00050758256,0.0015041019,0.00037172288,0.000677723],"domain_scores_gemma":[0.99772215,0.000038770988,0.00046976696,0.0011893681,0.00026667162,0.00031329546],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041876503,0.0006997104,0.00056459865,0.00016065412,0.00034903895,0.00030805884,0.0008338623,0.00047189058,0.00029556884],"category_scores_gemma":[0.00013835983,0.000702674,0.00018750135,0.00019993317,0.00010830452,0.000018867895,0.0007987602,0.00091503013,0.000015345606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014273141,0.00015381371,0.0016377047,0.0001411051,0.00034862643,0.00014371115,0.000012683134,0.005312002,0.9919552,0.00007629075,0.0000741234,0.0000019785832],"study_design_scores_gemma":[0.00048079094,0.0004936213,0.002862342,0.0002385171,0.00014364158,1.959604e-7,0.000023887927,0.0017259015,0.98926747,0.0000013381963,0.0036623017,0.0011000017],"about_ca_topic_score_codex":0.00009567816,"about_ca_topic_score_gemma":0.000012519488,"teacher_disagreement_score":0.0035881782,"about_ca_system_score_codex":0.00011796938,"about_ca_system_score_gemma":0.0003920679,"threshold_uncertainty_score":0.9995424},"labels":[],"label_agreement":null},{"id":"W4210780590","doi":"10.1111/bph.15811","title":"Community guidelines for GPCR ligand bias: IUPHAR review 32","year":2022,"lang":"en","type":"review","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":222,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Instituto de Salud Carlos III; H. Lundbeck A/S; Lundbeckfonden; Ministerio de Asuntos Económicos y Transformación Digital, Gobierno de España; Novo Nordisk; Novo Nordisk Fonden; Deutsche Forschungsgemeinschaft","keywords":"G protein-coupled receptor; Pharmacology; Medicine; Psychology; Receptor; Internal medicine","score_opus":0.2325725615710485,"score_gpt":0.446388033154362,"score_spread":0.2138154715833135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210780590","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000059252194,0.9960469,0.0004070777,0.00015861884,0.0021880101,0.0008044039,0.00027283936,0.000006314333,0.000056589866],"genre_scores_gemma":[0.000003026764,0.99282986,0.0012034583,0.0027816878,0.0022119805,0.00013956598,0.00038478943,0.00008508335,0.0003605277],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99613476,0.0013505913,0.001684253,0.00026197874,0.00022190256,0.00034652415],"domain_scores_gemma":[0.99718404,0.00018561988,0.0016595887,0.00016646684,0.00065964897,0.00014461385],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0035986162,0.0003475389,0.001836283,0.000104941486,0.00034173706,0.000041308722,0.000972676,0.0002948522,0.0012972443],"category_scores_gemma":[0.0009977617,0.00035686855,0.0013446955,0.00014764306,0.0000593638,0.000007362715,0.00029997886,0.0010678918,0.0000032310854],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000179555,0.00008480335,3.846885e-8,0.009903872,0.00045217152,0.00006899961,0.0000032299954,0.0000022238924,0.002381351,0.000001454418,0.34501305,0.64207083],"study_design_scores_gemma":[0.00067202264,0.00061201927,2.6204601e-8,0.010635703,0.0017999833,0.0046078213,0.000018165294,0.0000011269665,0.0021217102,0.00002276271,0.9791881,0.00032057814],"about_ca_topic_score_codex":0.00001664178,"about_ca_topic_score_gemma":0.0000061026158,"teacher_disagreement_score":0.6417503,"about_ca_system_score_codex":0.000058051588,"about_ca_system_score_gemma":0.0006116147,"threshold_uncertainty_score":0.9998883},"labels":[],"label_agreement":null},{"id":"W4210840207","doi":"10.1161/jaha.121.022070","title":"Myogenic Vasoconstriction Requires Canonical G <sub>q/11</sub> Signaling of the Angiotensin II Type 1 Receptor","year":2022,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"Myogenic contraction; Angiotensin II; Gq alpha subunit; Vasoconstriction; Endocrinology; Internal medicine; Mesenteric arteries; Vascular smooth muscle; Receptor; Cell biology; Transient receptor potential channel; Medicine; Signal transduction; Biology; G protein-coupled receptor; Artery; Smooth muscle","score_opus":0.008598313817043884,"score_gpt":0.2325810174965433,"score_spread":0.22398270367949943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210840207","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99711305,0.00022754136,0.00007832593,0.001522711,0.000937955,0.00009779373,0.0000106973,0.0000027040628,0.000009201274],"genre_scores_gemma":[0.99862176,0.0000676481,0.0002757728,0.00049893965,0.0004102928,0.0000022886993,0.0000029009796,0.000013727972,0.00010666045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983742,0.0005203932,0.00038037723,0.00011121858,0.00045389772,0.00015989252],"domain_scores_gemma":[0.9984242,0.000059251244,0.0010417291,0.00017124359,0.00026728812,0.00003633838],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010243474,0.00008596386,0.00024247565,0.00004126093,0.00036496602,0.000012394601,0.00022836249,0.000049748072,0.000029459492],"category_scores_gemma":[0.00036612753,0.000060187445,0.00039437064,0.0003899684,0.000045679626,0.0000069013377,0.00017804407,0.00023044505,5.7461057e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050060935,0.00003897366,0.018421741,0.0000011964826,0.000093053095,1.5247628e-7,0.0000741581,0.0014669893,0.96959084,0.000009020074,0.009603488,0.0006503165],"study_design_scores_gemma":[0.00022465286,0.0006033696,0.006329976,0.000016229964,0.00007832743,0.000028134096,0.0002805157,0.000055002773,0.97798306,0.00004766437,0.014265179,0.00008791408],"about_ca_topic_score_codex":0.00004847204,"about_ca_topic_score_gemma":0.000009710284,"teacher_disagreement_score":0.012091764,"about_ca_system_score_codex":0.00024859735,"about_ca_system_score_gemma":0.0002969092,"threshold_uncertainty_score":0.28070605},"labels":[],"label_agreement":null},{"id":"W4210960398","doi":"10.1139/y99-142","title":"Cardiovascular α<sub>1</sub>-adrenoceptor subtypes: functions and signaling","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Inotrope; Internal medicine; Endocrinology; Receptor; Vasoconstriction; Adrenergic receptor; Protein kinase A; Phospholipase C; G protein; Intracellular; Biology; Phospholipase; Signal transduction; Protein kinase C; Chemistry; Cell biology; Kinase; Medicine; Biochemistry; Enzyme","score_opus":0.00713050527021463,"score_gpt":0.21037059046817075,"score_spread":0.2032400851979561,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210960398","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990364,0.008680336,0.00012724665,0.000101668615,0.0005310503,0.00006945145,0.000016025342,0.0000023998207,0.000107831234],"genre_scores_gemma":[0.99720573,0.0013488708,0.00007424899,0.00047408033,0.0007839098,0.0000037669502,0.0000150273945,0.00001480309,0.00007955021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990993,0.00014733637,0.00021486352,0.00021394488,0.000044850607,0.00027969357],"domain_scores_gemma":[0.9993644,0.000021255408,0.000071476235,0.00008537743,0.000091130496,0.00036636],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00025085837,0.0001382109,0.0002610709,0.00009009103,0.00021277023,0.00001209819,0.00009753878,0.00018674319,0.0021223458],"category_scores_gemma":[0.000011201529,0.00013071371,0.00013658279,0.000057971694,0.00018986156,0.000009059528,0.00001168276,0.00020283627,0.000008249524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007195629,0.00000787691,0.00015273997,0.000016192324,0.00036194955,0.000019204834,0.00006443271,0.00054843817,0.9891629,0.000013211032,0.0015775454,0.008003519],"study_design_scores_gemma":[0.0006804153,0.00040082802,0.00041231018,0.000008111739,0.00015694356,0.00027233316,0.00006692167,0.000024037927,0.94752496,0.00023505122,0.050061617,0.00015645154],"about_ca_topic_score_codex":0.00008699414,"about_ca_topic_score_gemma":0.000113100556,"teacher_disagreement_score":0.048484072,"about_ca_system_score_codex":0.000012867888,"about_ca_system_score_gemma":0.00025857263,"threshold_uncertainty_score":0.99878985},"labels":[],"label_agreement":null},{"id":"W4211249976","doi":"10.1139/y00-100","title":"Somatostatin family of peptides and its receptors in fish","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Somatostatin; Receptor; Somatostatin receptor 1; Somatostatin receptor; G protein-coupled receptor; Somatostatin receptor 3; Endocrinology; Neuropeptide; Internal medicine; Somatostatin receptor 2; Genetics","score_opus":0.00911106867126853,"score_gpt":0.241170857019842,"score_spread":0.23205978834857346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4211249976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974412,0.0019683624,0.0000028164966,0.00015179004,0.00022827263,0.00005279211,0.000014560301,5.690559e-7,0.00013964181],"genre_scores_gemma":[0.99754006,0.001496807,0.00009715121,0.0006323417,0.000125551,0.0000016608425,0.0000064176706,0.000007040688,0.000092945855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993141,0.00011555731,0.00024185503,0.00011918782,0.000024795101,0.0001844778],"domain_scores_gemma":[0.9996131,0.000023942033,0.0000977905,0.000034987246,0.000054385142,0.00017577378],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016893462,0.000086867985,0.00020505882,0.00009209298,0.000043246535,0.0000029974915,0.00008463042,0.00012588808,0.0013279215],"category_scores_gemma":[0.000013800661,0.00008183655,0.00003468203,0.0000483399,0.00011081756,0.0000063449834,0.000008764522,0.00012667944,9.442978e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009037324,0.000009913103,0.0009153107,0.000024101024,0.000037263242,0.000010417561,0.00015751828,0.00008400163,0.99483865,0.000038296446,0.0014294079,0.0023647312],"study_design_scores_gemma":[0.0009416061,0.0005762568,0.0053936685,0.000020187636,0.000021587517,0.00007471889,0.00013210958,0.00004790943,0.97541004,0.00043775787,0.016827103,0.000117073134],"about_ca_topic_score_codex":0.00015197437,"about_ca_topic_score_gemma":0.000552234,"teacher_disagreement_score":0.019428644,"about_ca_system_score_codex":0.000006654305,"about_ca_system_score_gemma":0.00019465516,"threshold_uncertainty_score":0.999585},"labels":[],"label_agreement":null},{"id":"W4212824796","doi":"10.1016/j.celrep.2022.110386","title":"Postnatal regulation of B-1a cell development and survival by the CIC-PER2-BHLHE41 axis","year":2022,"lang":"en","type":"article","venue":"Cell Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Cell biology; Biology","score_opus":0.0062268424745486935,"score_gpt":0.19584032617853112,"score_spread":0.18961348370398243,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212824796","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99534416,0.0013306392,0.00051308324,0.000022605034,0.0002501303,0.00012230815,0.00000631955,0.000004478941,0.002406251],"genre_scores_gemma":[0.99612725,0.00002262932,0.0003713173,0.000036118552,0.000035048146,0.00001560144,0.00019027243,0.000013243922,0.0031885367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915075,0.000048914902,0.0002454594,0.00024284808,0.00019318631,0.000118851465],"domain_scores_gemma":[0.99951977,0.000007966328,0.00017715078,0.00022078531,0.000037857288,0.000036453057],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004054763,0.000088498295,0.0000915593,0.000015281432,0.00016860994,0.0000108346,0.00006977992,0.00004525361,0.0001831309],"category_scores_gemma":[0.0000097349275,0.00007337917,0.000039801667,0.000043904685,0.000025940975,0.0000019156626,0.00015579376,0.00006293704,4.4837185e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001801873,0.000034288372,0.0004253694,0.000013215996,0.000008734051,0.000011944058,0.0001675242,0.00007214494,0.9966325,0.000007830148,0.0016710915,0.00093734777],"study_design_scores_gemma":[0.000099808145,0.00009510317,0.0002838678,0.0000016811695,0.0000064373908,0.00006523666,0.00030181344,0.00001623834,0.9241458,0.000026838932,0.07486611,0.00009103637],"about_ca_topic_score_codex":0.000021834732,"about_ca_topic_score_gemma":0.000002243353,"teacher_disagreement_score":0.07319502,"about_ca_system_score_codex":0.000011961598,"about_ca_system_score_gemma":0.00006727471,"threshold_uncertainty_score":0.29923156},"labels":[],"label_agreement":null},{"id":"W4213458153","doi":"10.1016/j.cellsig.2022.110294","title":"IBD-associated G protein-coupled receptor 65 variant compromises signalling and impairs key functions involved in inflammation","year":2022,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University Health Centre; McGill University; Montreal Heart Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Canada Research Chairs; Canada Foundation for Innovation","keywords":"Inflammation; G protein-coupled receptor; Cell biology; Signalling; Key (lock); Receptor; G protein; Signal transduction; Chemistry; Biology; Immunology; Biochemistry","score_opus":0.011294360465905501,"score_gpt":0.19972209576935304,"score_spread":0.18842773530344753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213458153","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96274734,0.0011071817,0.035052992,0.00006138313,0.00018408403,0.00070242246,0.000016389498,0.000048073318,0.00008016416],"genre_scores_gemma":[0.99706507,0.000051722152,0.0012337744,0.00004684384,0.00021383437,0.00025089708,0.0006867626,0.00005858895,0.0003924907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978437,0.0002910672,0.00053211465,0.00059002993,0.0003162048,0.00042691198],"domain_scores_gemma":[0.99927485,0.000038514903,0.0002562525,0.00020133269,0.00010610733,0.00012296575],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011063806,0.00027693153,0.00029872495,0.00016343388,0.00052968634,0.00008965319,0.00018723891,0.00017263737,0.00048570128],"category_scores_gemma":[0.00009916458,0.00031137178,0.00012503006,0.00030030278,0.000042001247,0.000017511673,0.00021080534,0.00036007847,0.0000069218017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012950602,0.00009844342,0.00022090146,0.000030518622,0.000073427844,0.00002130455,0.00030218824,0.017706603,0.9809859,0.00014011636,0.000033573073,0.0002575557],"study_design_scores_gemma":[0.0018073836,0.00055502646,0.000032420136,0.00008095389,0.000043466724,0.000007932507,0.0011633423,0.056496236,0.93664974,0.0004379892,0.002152504,0.000572991],"about_ca_topic_score_codex":0.000074491996,"about_ca_topic_score_gemma":0.000037812835,"teacher_disagreement_score":0.044336107,"about_ca_system_score_codex":0.00010268094,"about_ca_system_score_gemma":0.00013045715,"threshold_uncertainty_score":0.99993384},"labels":[],"label_agreement":null},{"id":"W4213460059","doi":"10.18433/j3gp53","title":"Understanding the Hysteresis Loop Conundrum in Pharmacokinetic / Pharmacodynamic Relationships","year":2014,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":96,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Pharmacodynamics; Hysteresis; Pharmacokinetics; Drug; Drug action; Pharmacology; Chemistry; Biophysics; Biological system; Biology; Physics","score_opus":0.16282124366765977,"score_gpt":0.37291719967315495,"score_spread":0.2100959560054952,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213460059","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95749223,0.002128652,0.03407827,0.00290634,0.0011034398,0.00024101968,0.000003575225,0.000009809407,0.002036681],"genre_scores_gemma":[0.99709857,0.00086171087,0.000381743,0.0010160141,0.0005346121,0.0000049293203,0.0000015568462,0.000016407486,0.00008447875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973573,0.00070545514,0.0006533549,0.00028412865,0.00054193067,0.0004578486],"domain_scores_gemma":[0.9989698,0.00028644054,0.00031244432,0.0001151092,0.00009193506,0.00022428563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0039341813,0.00020256302,0.00023128277,0.00017388341,0.00037249297,0.000109944114,0.00070401846,0.00005364221,0.00032450588],"category_scores_gemma":[0.00022774182,0.0001367624,0.00017344035,0.00046483523,0.0003722164,0.000044577835,0.000108632514,0.00055896497,0.000010510886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002105993,0.000105606196,0.009306123,0.00002419612,0.00005789905,0.000010507719,0.00012923713,0.0060790363,0.971633,0.0012518595,0.0007495802,0.010442316],"study_design_scores_gemma":[0.0069678775,0.00054000114,0.00079418713,0.00012960615,0.000274086,0.00035346625,0.0012191549,0.1823018,0.65022045,0.0029185987,0.15360571,0.00067508314],"about_ca_topic_score_codex":0.000006051183,"about_ca_topic_score_gemma":0.0000066795146,"teacher_disagreement_score":0.32141262,"about_ca_system_score_codex":0.00007267112,"about_ca_system_score_gemma":0.00013212822,"threshold_uncertainty_score":0.55770093},"labels":[],"label_agreement":null},{"id":"W4214889856","doi":"10.1152/ajpcell.00044.2022","title":"Dynamics and mechanistic underpinnings to pharmacology of class A GPCRs: an NMR perspective","year":2022,"lang":"en","type":"review","venue":"American Journal of Physiology-Cell Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Allosteric regulation; G protein-coupled receptor; Computational biology; Receptor; Signal transduction; Drug discovery; Neuroscience; Biology; Chemistry; Biophysics; Bioinformatics; Cell biology; Biochemistry","score_opus":0.015547094321814845,"score_gpt":0.3097182277463042,"score_spread":0.29417113342448936,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4214889856","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.104862295,0.8907458,0.0013239013,0.00011860144,0.0014767414,0.0009917127,0.00027040613,0.00002111888,0.00018938757],"genre_scores_gemma":[0.06769811,0.9286733,0.00174111,0.00051024446,0.0009093361,0.000060002745,0.0002038826,0.00013481131,0.00006916791],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9961226,0.0012076327,0.0010612593,0.0008651316,0.00019148565,0.00055186776],"domain_scores_gemma":[0.9964309,0.00021525103,0.002327368,0.00045513688,0.00027307126,0.00029831953],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004501918,0.0006312853,0.0028366572,0.00039230994,0.00013790312,0.000010615188,0.0008785878,0.00031621175,0.00032568286],"category_scores_gemma":[0.000078863006,0.00055190147,0.00065798557,0.00039780978,0.00059618487,0.000011225629,0.0005191838,0.000803813,0.0000037711434],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045939555,0.0003233623,2.1881365e-7,0.00076177035,0.0007772249,0.000008308704,0.00020736376,0.0002814479,0.9440291,0.0008355934,0.00030752836,0.052008674],"study_design_scores_gemma":[0.0032370859,0.07640541,0.000022939217,0.0012939655,0.0045620194,0.001131223,0.012945729,0.0005199605,0.035334766,0.006721182,0.8543649,0.0034608222],"about_ca_topic_score_codex":0.00006280366,"about_ca_topic_score_gemma":0.000005601472,"teacher_disagreement_score":0.9086943,"about_ca_system_score_codex":0.00019094133,"about_ca_system_score_gemma":0.0005839173,"threshold_uncertainty_score":0.9996933},"labels":[],"label_agreement":null},{"id":"W4220702253","doi":"10.1016/j.cub.2022.02.035","title":"Synaptic inhibition in the lateral habenula shapes reward anticipation","year":2022,"lang":"en","type":"article","venue":"Current Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Novartis Foundation","keywords":"Neuroscience; Licking; Postsynaptic potential; Optogenetics; GABAA receptor; Biology; Anticipation (artificial intelligence); Habenula; Long-term potentiation; Receptor; Pharmacology; Central nervous system; Computer science","score_opus":0.02492279458565382,"score_gpt":0.29180662399240537,"score_spread":0.26688382940675154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220702253","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997028,0.0012186461,0.0008782741,0.00019053955,0.00044593366,0.00014765773,0.000018238228,0.0000065733925,0.00006613429],"genre_scores_gemma":[0.9989307,0.00009394161,0.00003095257,0.00021713057,0.00015673893,0.000087110995,0.0004665359,0.0000066383486,0.00001027088],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.999134,0.0002585775,0.0001543981,0.0002165004,0.00006212088,0.0001744056],"domain_scores_gemma":[0.99979174,0.0000118962,0.000055313616,0.0001091536,0.000016141794,0.000015767106],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034469177,0.00008148424,0.00008280878,0.00004565872,0.00011988776,0.000010383768,0.00010725912,0.000050164068,0.00014740837],"category_scores_gemma":[0.000025213483,0.000063335494,0.000048746842,0.00008316046,0.000029815143,0.0000020883053,0.000101190635,0.00013797084,0.0000057294624],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056539375,0.000121628116,0.005244313,0.000012008919,0.00001986767,0.0000036772456,0.00031025347,0.00032168836,0.9847365,0.001959239,0.0006926694,0.0065216036],"study_design_scores_gemma":[0.0055726124,0.006750224,0.030688435,0.00010523772,0.00013839915,0.00033406654,0.0022118392,0.0072622444,0.3477045,0.021700913,0.5754458,0.002085741],"about_ca_topic_score_codex":0.00001251046,"about_ca_topic_score_gemma":0.000011131243,"teacher_disagreement_score":0.63703203,"about_ca_system_score_codex":0.000014597683,"about_ca_system_score_gemma":0.000020847687,"threshold_uncertainty_score":0.25827464},"labels":[],"label_agreement":null},{"id":"W4220763721","doi":"10.7554/elife.74101","title":"Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs","year":2022,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":258,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Novo Nordisk Fonden; Lundbeckfonden; Canada Research Chairs; Canadian Institutes of Health Research; Bristol-Myers Squibb","keywords":"G protein-coupled receptor; Effector; Arrestin; Chromosomal translocation; Cell biology; Computational biology; Biology; Membrane protein; Coupling (piping); Chemistry; Membrane; Biophysics; Signal transduction; Biochemistry; Gene; Materials science","score_opus":0.011478074529818751,"score_gpt":0.23836139431479442,"score_spread":0.22688331978497567,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220763721","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972485,0.0012595438,0.0007341728,0.00019067705,0.00007386237,0.0004265714,0.000022455533,0.0000129583,0.000031290165],"genre_scores_gemma":[0.9977677,0.00010330099,0.0016743834,0.000075611955,0.00008118757,0.00008187033,0.00005358738,0.000020764048,0.00014162436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991379,0.00007401408,0.00020881768,0.00023923663,0.00019790986,0.00014212649],"domain_scores_gemma":[0.9996597,0.000017694789,0.000080290454,0.00014756639,0.000047792462,0.000046927296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042087105,0.00010413963,0.00013742733,0.000031989955,0.00011360136,0.000008860866,0.000092847054,0.000059198042,0.00006543224],"category_scores_gemma":[0.000047663383,0.00009653145,0.00004812977,0.00007077025,0.000040971358,0.000002050561,0.00004412075,0.00009633013,0.0000012389172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013408436,0.00003628804,0.000106031126,0.000053398784,0.000026035234,0.0000011710333,0.000075168675,0.00042647333,0.9977528,0.00014237686,0.000028351464,0.0012178578],"study_design_scores_gemma":[0.000379287,0.00044390062,0.0001897325,0.00003000953,0.000011578035,0.000005689575,0.00009807191,0.0008996987,0.99568766,0.00001837112,0.0021176755,0.0001183239],"about_ca_topic_score_codex":0.000015036438,"about_ca_topic_score_gemma":0.0000018284867,"teacher_disagreement_score":0.002089324,"about_ca_system_score_codex":0.000008082113,"about_ca_system_score_gemma":0.000051867715,"threshold_uncertainty_score":0.39364383},"labels":[],"label_agreement":null},{"id":"W4220899139","doi":"10.7554/elife.74107","title":"Common coupling map advances GPCR-G protein selectivity","year":2022,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":131,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Daiichi Sankyo Europe; Japan Society for the Promotion of Science; Novo Nordisk Fonden; H. Lundbeck A/S; Japan Science and Technology Agency; Daiichi Sankyo Foundation of Life Science; Lundbeckfonden; Uehara Memorial Foundation; Japan Agency for Medical Research and Development; Danmarks Frie Forskningsfond; Canadian Institutes of Health Research; Novo Nordisk; Takeda Science Foundation","keywords":"G protein-coupled receptor; G protein; Receptor; Coupling (piping); Protein–protein interaction; Functional selectivity; Drug discovery; Structural biology","score_opus":0.007238288805933478,"score_gpt":0.2396284067711913,"score_spread":0.23239011796525783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220899139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99412,0.0023442293,0.0025837559,0.00011085984,0.00024454203,0.00020317108,0.000013466489,0.000024033272,0.00035596365],"genre_scores_gemma":[0.99779123,0.000033011987,0.0007702464,0.00020283106,0.00021609226,0.00010327024,0.00005721235,0.00001847693,0.000807636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992193,0.000042681546,0.000116301766,0.00024259253,0.00019600858,0.00018313724],"domain_scores_gemma":[0.999689,0.000005222423,0.000060184182,0.00016897157,0.000030688807,0.000045964745],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028261187,0.00009377659,0.00010212951,0.000019657407,0.00027861595,0.00001536214,0.00014716278,0.000038832623,0.0002518117],"category_scores_gemma":[0.000018031325,0.00009791484,0.00005665346,0.000064809064,0.000014804971,0.0000030577385,0.00015826173,0.00013087277,0.000008433651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004492707,0.00004254782,0.00055757444,0.000009936141,0.0000134944585,0.0000024121532,0.000021844813,0.0024830329,0.9945397,0.00019756956,0.0007990641,0.0012879068],"study_design_scores_gemma":[0.0001732281,0.00023215104,0.000037276575,0.000003732018,0.000003300165,0.000004038042,0.00008739329,0.0006543386,0.7737252,0.000096496995,0.22485435,0.00012847193],"about_ca_topic_score_codex":0.000015669206,"about_ca_topic_score_gemma":0.0000129739665,"teacher_disagreement_score":0.22405529,"about_ca_system_score_codex":0.000019365969,"about_ca_system_score_gemma":0.00004359805,"threshold_uncertainty_score":0.3992851},"labels":[],"label_agreement":null},{"id":"W4220968017","doi":"10.21203/rs.3.rs-1409064/v1","title":"Mapping the conformational landscape of the stimulatory heterotrimeric G protein","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Japan Science and Technology Agency; Core Research for Evolutional Science and Technology; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Heterotrimeric G protein; Chemistry; Cell biology; Computational biology; G protein; Biology; Signal transduction","score_opus":0.057248960715314955,"score_gpt":0.3382961014311834,"score_spread":0.28104714071586845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220968017","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930176,0.0022787882,0.0006347864,0.00030921202,0.00024142597,0.0016201967,0.00012526661,0.000007773388,0.0017649339],"genre_scores_gemma":[0.99817,0.000065444125,0.00011314452,0.000039865667,0.00020573617,0.00034474052,0.00017518886,0.000020093712,0.0008657911],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9978228,0.0005538591,0.00026036438,0.00026944702,0.0008212986,0.00027223257],"domain_scores_gemma":[0.99879116,0.00004254954,0.0001566303,0.0007061622,0.00026127728,0.000042206422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014942185,0.00013228632,0.00014430365,0.0000817632,0.00037230804,0.0000476244,0.00082216103,0.00015955653,0.0007381063],"category_scores_gemma":[0.00017912505,0.00008068897,0.00020805464,0.00018810642,0.00012353674,0.0000020528894,0.0021378656,0.000831878,0.0000044523194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016468833,0.0001287398,0.002082475,0.0011571791,0.00029228002,0.0000025618444,0.0011645849,0.02126701,0.96334857,0.0013836593,0.0060204035,0.002987831],"study_design_scores_gemma":[0.0013351062,0.00085535046,0.009718272,0.00094554824,0.000025098867,0.000014466355,0.007244891,0.0081351865,0.7187668,0.0035752577,0.24853279,0.0008512065],"about_ca_topic_score_codex":0.000040909417,"about_ca_topic_score_gemma":0.0000027128108,"teacher_disagreement_score":0.24458174,"about_ca_system_score_codex":0.000031975498,"about_ca_system_score_gemma":0.00047999673,"threshold_uncertainty_score":0.80817467},"labels":[],"label_agreement":null},{"id":"W4220992323","doi":"10.1515/dx-2021-0147","title":"Convoluted molecular maze of neprilysin","year":2022,"lang":"en","type":"letter","venue":"Diagnosis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital","funders":"","keywords":"Neprilysin; Thiorphan; Chemistry; Biochemistry; Enzyme","score_opus":0.010011327377457356,"score_gpt":0.22566406023683172,"score_spread":0.21565273285937436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220992323","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5720424,0.03026686,0.0072409436,0.37116024,0.0063196775,0.0030070867,0.002829045,0.00017752776,0.0069562243],"genre_scores_gemma":[0.13250105,0.002967188,0.0026307395,0.84191674,0.003802731,0.0012874573,0.011239225,0.00038620207,0.0032686698],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984274,0.00014398557,0.00031598046,0.00050781167,0.00031169617,0.0002931235],"domain_scores_gemma":[0.999042,0.00003564189,0.0002272704,0.0005728315,0.000081952174,0.000040312574],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013767934,0.00026776496,0.00036350483,0.00009344535,0.00004157648,0.000017367478,0.00041600876,0.00057263026,0.0032339774],"category_scores_gemma":[0.000067819165,0.00028980384,0.0003484811,0.00012394032,0.00004808778,0.0000013327742,0.00024538877,0.0004836702,0.000012260867],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013964812,0.000037173915,0.00020973073,0.00007248834,0.00020700699,0.00009196358,0.000020348114,0.000050620896,0.17020433,0.00003333557,0.8284896,0.0005694129],"study_design_scores_gemma":[0.00014208625,0.0001722249,0.000008087753,0.000016918815,0.000056691675,0.000003868606,0.0000108413515,0.000004995415,0.35167462,0.00007635849,0.6476188,0.00021454741],"about_ca_topic_score_codex":0.00008554228,"about_ca_topic_score_gemma":0.0000017943868,"teacher_disagreement_score":0.4707565,"about_ca_system_score_codex":0.000021878875,"about_ca_system_score_gemma":0.000075628486,"threshold_uncertainty_score":0.9999554},"labels":[],"label_agreement":null},{"id":"W4221083797","doi":"10.1152/ajpcell.00031.2022","title":"Neuronal cholinergic signaling constrains norepinephrine activity in the heart","year":2022,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Pró-Reitoria de Pesquisa, Universidade Federal de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Ministério da Ciência, Tecnologia e Inovação; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Vesicular acetylcholine transporter; Cholinergic; Internal medicine; Endocrinology; Acetylcholine; Choline acetyltransferase; Norepinephrine; Cholinergic neuron; Chemistry; Biology; Medicine; Dopamine","score_opus":0.008290052968471308,"score_gpt":0.23471537875859314,"score_spread":0.22642532579012184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221083797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99873674,0.00018102379,0.0001009597,0.00045590493,0.0003108365,0.0001195498,0.000017720273,0.0000045604543,0.0000726774],"genre_scores_gemma":[0.99652636,0.000060438546,0.00038305277,0.0023604452,0.00057408895,0.000021251277,0.000030039657,0.00002423203,0.0000200921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99749976,0.0010732968,0.00044146052,0.00036491605,0.00021055937,0.00040999986],"domain_scores_gemma":[0.9988068,0.00012624344,0.000590686,0.00031749575,0.00008426006,0.00007452616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006368184,0.00022968724,0.00051121705,0.000117070034,0.00019580805,0.000009115921,0.0006194594,0.000054347005,0.0002079623],"category_scores_gemma":[0.000038224407,0.00017641272,0.00029646108,0.00028804716,0.00038980457,0.000008608098,0.00020957211,0.00069340854,0.0000030871015],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052491215,0.0002906197,0.000101736696,0.0000051880706,0.00003762314,0.0000055556934,0.000114614595,0.021508683,0.976327,0.000034572255,0.0006701425,0.00037937093],"study_design_scores_gemma":[0.0028078416,0.012066594,0.03244027,0.000010493149,0.000059977814,0.0005223279,0.0030818244,0.00046314154,0.92829764,0.001091635,0.018504735,0.0006535174],"about_ca_topic_score_codex":0.000035629466,"about_ca_topic_score_gemma":0.000003020259,"teacher_disagreement_score":0.04802934,"about_ca_system_score_codex":0.000026179932,"about_ca_system_score_gemma":0.00017154662,"threshold_uncertainty_score":0.7193902},"labels":[],"label_agreement":null},{"id":"W4221116614","doi":"10.1038/s41467-022-29231-6","title":"Adipocyte Gq signaling is a regulator of glucose and lipid homeostasis in mice","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Japan Society for the Promotion of Science; Canadian Institutes of Health Research; University of North Carolina at Chapel Hill; Diabetes Canada; National Institutes of Health; Rheinische Friedrich-Wilhelms-Universität Bonn; Central Michigan University; Joslin Diabetes Center","keywords":"Adipocyte; Glucose homeostasis; Lipolysis; Internal medicine; Endocrinology; Insulin resistance; Receptor; Insulin receptor; Glucose uptake; Insulin; Adipose tissue; Biology; Chemistry; Medicine","score_opus":0.011589272072903679,"score_gpt":0.26331550978315116,"score_spread":0.2517262377102475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4221116614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9549855,0.04365401,0.000074846284,0.00071880245,0.000069540925,0.00014929159,0.00007497535,0.0000064909314,0.000266523],"genre_scores_gemma":[0.993544,0.0014785934,0.0042572096,0.00038418683,0.000025185323,0.00003742748,0.00019214956,0.000012892142,0.00006837035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993216,0.00012948223,0.00018013443,0.00016491988,0.00009933822,0.00010455068],"domain_scores_gemma":[0.9991487,0.00003642642,0.00008989733,0.0006339113,0.000057773377,0.000033282067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026949155,0.00007760941,0.00011307376,0.00007013898,0.000167553,0.000009021305,0.00045688552,0.000120913806,0.00007515313],"category_scores_gemma":[0.000045691166,0.00008549974,0.000044844073,0.00017963343,0.000047525875,0.0000031936447,0.0005348528,0.0003567244,4.643952e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027732995,0.000063257874,0.00042983156,0.0000075887033,0.000025246201,2.3666723e-7,0.0002894767,0.00004348978,0.9958423,0.0010793982,0.0004899453,0.0017015282],"study_design_scores_gemma":[0.00041418683,0.000118772834,0.00047799133,0.000014565511,0.000020552574,0.000009395184,0.00059272326,0.00034313885,0.83356935,0.00017827391,0.16411068,0.00015038741],"about_ca_topic_score_codex":0.000031172982,"about_ca_topic_score_gemma":0.00006377262,"teacher_disagreement_score":0.16362074,"about_ca_system_score_codex":0.000016996919,"about_ca_system_score_gemma":0.00004767296,"threshold_uncertainty_score":0.34865785},"labels":[],"label_agreement":null},{"id":"W4223574847","doi":"10.1042/bcj20210528","title":"Allosteric pluripotency: challenges and opportunities","year":2022,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Allosteric regulation; Allosteric enzyme; Induced pluripotent stem cell; Allosteric modulator; Drug discovery","score_opus":0.039737260663348276,"score_gpt":0.23536555264237705,"score_spread":0.19562829197902876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223574847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9514621,0.04568578,0.00024913953,0.0013006696,0.00027847255,0.000051449875,0.000008440794,0.000008484994,0.000955483],"genre_scores_gemma":[0.98608,0.011935985,0.00059497374,0.0005039692,0.00042122835,0.000010693885,0.000019230485,0.000017187083,0.00041672582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992574,0.000067684276,0.00015051763,0.00017566362,0.00016947671,0.0001792972],"domain_scores_gemma":[0.9996592,0.0000056863687,0.00006736891,0.000101036174,0.0000327488,0.00013395853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025402274,0.000099919176,0.0000973722,0.00003395297,0.00019717231,0.000026207972,0.00014874987,0.000052618114,0.00027288447],"category_scores_gemma":[0.000017711975,0.000093443276,0.0000634634,0.000016184144,0.000039617174,0.0000028149757,0.00023806692,0.0001755374,9.2144376e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046865734,0.000028687486,0.0000067594933,0.000006224095,0.000029706858,0.00002062278,0.00009089752,0.0000029484822,0.97710836,0.00030675618,0.0027218799,0.01963031],"study_design_scores_gemma":[0.0008486691,0.0009887585,0.00010834305,0.000016397442,0.00002984678,0.0031806706,0.0023092097,0.000045532888,0.57296485,0.0021676018,0.41689977,0.00044037346],"about_ca_topic_score_codex":5.508701e-7,"about_ca_topic_score_gemma":9.9995354e-8,"teacher_disagreement_score":0.4141779,"about_ca_system_score_codex":0.000013077531,"about_ca_system_score_gemma":0.000050552593,"threshold_uncertainty_score":0.38105062},"labels":[],"label_agreement":null},{"id":"W4223601970","doi":"10.7554/elife.74107.sa2","title":"Author response: Common coupling map advances GPCR-G protein selectivity","year":2022,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"G protein-coupled receptor; Computational biology; Coupling (piping); Computer science; Biology; Chemistry; Receptor; Genetics; Materials science","score_opus":0.02348913608084536,"score_gpt":0.32403743526523765,"score_spread":0.3005482991843923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4223601970","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04672179,0.832468,0.015143514,0.07652362,0.011977062,0.008745392,0.0018192761,0.00042947129,0.006171901],"genre_scores_gemma":[0.009081409,0.00403825,0.0027831064,0.002016594,0.0010819326,0.0010224786,0.0034083826,0.00019026038,0.9763776],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972526,0.0003388373,0.00048776442,0.0009208174,0.0005340362,0.00046597348],"domain_scores_gemma":[0.9985974,0.000049078393,0.0003411719,0.0007038161,0.00017910634,0.0001294369],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0019622645,0.00048033491,0.0006779545,0.000079416015,0.00031347838,0.000049197908,0.0005471374,0.0004219079,0.005474658],"category_scores_gemma":[0.0002713721,0.00044894835,0.00033265888,0.00017470602,0.000044005235,0.0000048913444,0.00043473928,0.0006564355,0.00002751348],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033841762,0.00007075043,0.000004585682,0.001345661,0.0000926108,0.000010957536,0.000008534854,0.00010120287,0.29570767,0.000049273924,0.69924814,0.0030221792],"study_design_scores_gemma":[0.00016101317,0.00047721583,0.0000013913498,0.00049344514,0.000053042342,0.000011088407,0.000028536157,0.00006360219,0.1279456,0.00007920022,0.87017894,0.00050690054],"about_ca_topic_score_codex":0.00008533538,"about_ca_topic_score_gemma":0.00010190292,"teacher_disagreement_score":0.97020566,"about_ca_system_score_codex":0.000082896324,"about_ca_system_score_gemma":0.0003970699,"threshold_uncertainty_score":0.9997962},"labels":[],"label_agreement":null},{"id":"W4224301397","doi":"10.1016/j.xpro.2022.101347","title":"A live-imaging protocol for tracking receptor dynamics in single cells","year":2022,"lang":"en","type":"article","venue":"STAR Protocols","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Japan Society for the Promotion of Science","keywords":"Electroporation; Endocytosis; Receptor; Cell biology; Live cell imaging; Protocol (science); Chemistry; Cell; Computer science; Biophysics; Biology; Medicine; Biochemistry; Pathology","score_opus":0.028153397501082495,"score_gpt":0.3122245168152898,"score_spread":0.2840711193142073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224301397","genre_codex":"protocol","genre_gemma":"protocol","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"protocol","genre_consensus":"protocol","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009311966,0.000004660597,0.007168749,0.000083253646,0.000085278254,0.98272604,0.00010259489,0.000030542462,0.00048693237],"genre_scores_gemma":[0.014843618,1.0417391e-7,0.007422661,0.00013914291,0.0001400213,0.9769061,0.000084451305,0.00005293731,0.00041095898],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985448,0.00012117022,0.0003257703,0.00044654214,0.00018439948,0.00037732057],"domain_scores_gemma":[0.9994501,0.000016383374,0.00014624352,0.00026237304,0.00006731203,0.00005760341],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005611286,0.00017822687,0.00017354608,0.00006793791,0.00020907339,0.000059208534,0.00027874438,0.000060411683,0.00056227733],"category_scores_gemma":[0.000038875634,0.00019126685,0.00011491594,0.00011427556,0.000023364397,0.000007790581,0.00018143025,0.00015968268,0.0000045667975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054202764,0.00029569282,0.00051840185,0.00013081002,0.000010814277,0.0000031755824,0.00015228873,0.00034571954,0.98966235,0.00022361438,0.00128026,0.006834863],"study_design_scores_gemma":[0.0026225736,0.0012538388,0.000011326795,0.000075366836,0.0000029113735,0.000004400374,0.00088474737,0.0031833681,0.668728,0.00047267522,0.3224078,0.0003529727],"about_ca_topic_score_codex":0.000019070014,"about_ca_topic_score_gemma":0.00003350819,"teacher_disagreement_score":0.32112756,"about_ca_system_score_codex":0.00018752848,"about_ca_system_score_gemma":0.00011344574,"threshold_uncertainty_score":0.7799636},"labels":[],"label_agreement":null},{"id":"W4224438388","doi":"10.1007/7854_2022_315","title":"A Historical Perspective on the Dopamine D3 Receptor","year":2022,"lang":"en","type":"article","venue":"Current topics in behavioral neurosciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Dopamine receptor D3; Dopamine receptor D2; Neuroscience; Receptor; Dopamine receptor; Dopamine; Addiction; Schizophrenia (object-oriented programming); Adenylyl cyclase; Psychology; Dopamine hypothesis of schizophrenia; Cognition; D1-like receptor; Biology; Pharmacology; Medicine; Psychiatry; Stimulation; Internal medicine","score_opus":0.06323146629630662,"score_gpt":0.32871256361229945,"score_spread":0.26548109731599284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224438388","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936206,0.00066351454,0.00003671395,0.0009702683,0.00437805,0.00016212201,0.000007873385,0.000007921683,0.00015295298],"genre_scores_gemma":[0.99808025,0.00007561661,0.0000372759,0.00012890022,0.00022610657,0.000083237246,0.0000043060772,0.000007138977,0.001357144],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9988925,0.00012584393,0.00014020994,0.00036620573,0.00028398316,0.00019126968],"domain_scores_gemma":[0.999681,0.000011109107,0.000054336913,0.00018933426,0.000025070398,0.000039131042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022501819,0.000099461926,0.0000847203,0.000050679286,0.00028930855,0.000028735949,0.00039680532,0.000023122828,0.00014715895],"category_scores_gemma":[0.000056990244,0.00007387211,0.00006489237,0.00021062962,0.00006251069,0.0000036282245,0.00019166454,0.0002527129,0.0000017998309],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008204984,0.0014391452,0.013532019,0.000005023157,0.0000021209792,0.0000120987925,0.0005397036,0.00029577818,0.9449567,0.01489264,0.0090839155,0.015158809],"study_design_scores_gemma":[0.00039267627,0.0025977865,0.0018972303,0.0000108110435,0.0000092401,0.000011264412,0.0015983676,0.00010678803,0.08704799,0.00058775686,0.90534055,0.00039954428],"about_ca_topic_score_codex":0.000037537277,"about_ca_topic_score_gemma":0.000007316339,"teacher_disagreement_score":0.8962566,"about_ca_system_score_codex":0.00016493932,"about_ca_system_score_gemma":0.000048012284,"threshold_uncertainty_score":0.30124173},"labels":[],"label_agreement":null},{"id":"W4225269995","doi":"10.3389/fnins.2022.868541","title":"Role of Teneurin C-Terminal Associated Peptides (TCAP) on Intercellular Adhesion and Communication","year":2022,"lang":"en","type":"review","venue":"Frontiers in Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Cell biology; Biology; Synaptogenesis; Cell adhesion; Transmembrane protein; Receptor; Downregulation and upregulation; G protein-coupled receptor; Gene; Signal transduction; Genetics; Cell","score_opus":0.025415619667949887,"score_gpt":0.2752157877939415,"score_spread":0.24980016812599162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225269995","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010200099,0.9888601,0.00011993892,0.0000029146765,0.00035629046,0.00028136198,0.000025932406,0.0000058325854,0.00014753533],"genre_scores_gemma":[0.007022544,0.9922334,0.0004227331,0.000029297013,0.000014335394,0.00003514569,0.00008028444,0.000021961596,0.00014031176],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985402,0.0003364388,0.0003221619,0.00044622427,0.00018356406,0.00017135919],"domain_scores_gemma":[0.9992693,0.00002357807,0.00028301863,0.00036775705,0.000014639814,0.000041698542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040643377,0.00019059412,0.000452998,0.00016602909,0.000094627125,0.00002411279,0.0005323841,0.000137628,0.000008180882],"category_scores_gemma":[0.00020670111,0.00017603904,0.00012412843,0.00023284636,0.00011609693,0.0000053634853,0.00032955484,0.00025536714,2.6263316e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036618116,0.00023186485,0.00022478386,0.0011221638,0.000016282584,0.000017138109,0.00014165555,0.000028869199,0.099124335,0.000063202046,0.0005644572,0.8984286],"study_design_scores_gemma":[0.00019964429,0.0008463293,0.000052314957,0.0025768667,0.000060114504,0.000029249244,0.00013783912,0.00037561625,0.008348534,0.00015017939,0.9868364,0.0003869146],"about_ca_topic_score_codex":0.0000062680033,"about_ca_topic_score_gemma":0.0000014657749,"teacher_disagreement_score":0.9862719,"about_ca_system_score_codex":0.000033863045,"about_ca_system_score_gemma":0.000058806618,"threshold_uncertainty_score":0.7178664},"labels":[],"label_agreement":null},{"id":"W4225327644","doi":"10.3389/fncel.2022.907558","title":"Editorial: GPCR and G Protein-Mediated Signalling Events in the Nervous System","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Cellular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"Neuroscience; G protein-coupled receptor; Signalling; Nervous system; Neurophysiology; Biology; Signal transduction; Cell biology","score_opus":0.0058969159813994886,"score_gpt":0.2075077968997045,"score_spread":0.201610880918305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225327644","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01678819,0.0012563018,0.0037431163,0.000019117442,0.9772763,0.00079955487,0.000057111032,0.000016030308,0.000044237557],"genre_scores_gemma":[0.063895404,0.0004142981,0.00038551647,0.00006433806,0.9340987,0.000317469,0.0003532228,0.00008516305,0.00038587878],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.996336,0.00056514045,0.0004504274,0.0010119831,0.0011254475,0.0005110206],"domain_scores_gemma":[0.9991106,0.00006497769,0.00024938272,0.00043873914,0.000056038232,0.00008026795],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0018445753,0.00034339947,0.00037013728,0.00018294255,0.00022907283,0.000083018924,0.0011203409,0.0005461321,0.0000042561455],"category_scores_gemma":[0.00068785937,0.00029634227,0.000092121765,0.00041718618,0.000106713014,0.000011013466,0.00032912672,0.0009894995,7.841169e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066412955,0.00005084514,0.00009703481,0.000116231546,0.000004416006,0.00005161905,0.00009614653,0.00044105804,0.40518132,0.0000063060006,0.59380275,0.00008583149],"study_design_scores_gemma":[0.0005243924,0.00033080822,0.0000065704826,0.000105637206,0.000013716588,0.0000031066995,0.00043726416,0.0012277713,0.00965397,0.00004411928,0.98725104,0.00040162247],"about_ca_topic_score_codex":0.00007065048,"about_ca_topic_score_gemma":0.00000736213,"teacher_disagreement_score":0.39552736,"about_ca_system_score_codex":0.00009448739,"about_ca_system_score_gemma":0.00028857565,"threshold_uncertainty_score":0.99994886},"labels":[],"label_agreement":null},{"id":"W4225392384","doi":"10.1096/fasebj.2022.36.s1.r6324","title":"Regulation of Endothelial Cell function by Integration of Gαi and β‐arrestin signaling at Atypical Chemokine Receptor 3","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"G protein-coupled receptor; Chemokine receptor; Cell biology; Pertussis toxin; Arrestin; Receptor; Signal transduction; Co-receptor; Biology; C-C chemokine receptor type 7; Angiogenesis; Chemokine; G protein; Chemistry; Cancer research; Biochemistry","score_opus":0.008207651249255423,"score_gpt":0.20320122509294128,"score_spread":0.19499357384368585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225392384","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881022,0.0004391449,0.011025074,0.00005776352,0.00020888161,0.00007314382,0.000035122688,0.000002122133,0.000056528796],"genre_scores_gemma":[0.9987266,0.000055775276,0.0004969093,0.000030983523,0.00018292472,0.0000036197343,0.00007768849,0.000009916022,0.00041555928],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992568,0.00013367501,0.00023787684,0.00010344581,0.00017991936,0.000088321176],"domain_scores_gemma":[0.9995456,0.0000195428,0.0002525111,0.00008838391,0.000060242717,0.00003377237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004950443,0.00007244837,0.00009692547,0.000026554444,0.00019865565,0.000008839456,0.00008480559,0.000042985175,0.000572718],"category_scores_gemma":[0.00002858682,0.00005484215,0.000060473598,0.0000510099,0.0000386395,0.0000041227877,0.00007045947,0.00013375991,5.118373e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006533715,0.000028530785,0.00015745501,0.000005664249,0.000015670757,1.2458685e-7,0.00009612097,0.00062910223,0.9958196,0.00003693802,0.0009188899,0.0016385203],"study_design_scores_gemma":[0.0004683598,0.00046722923,0.00010538181,0.0000086024165,0.000023153138,0.000027083679,0.00024786234,0.0003920013,0.99638283,0.00016040372,0.0016600164,0.0000570637],"about_ca_topic_score_codex":0.000005276118,"about_ca_topic_score_gemma":8.6516e-7,"teacher_disagreement_score":0.010624405,"about_ca_system_score_codex":0.000021643713,"about_ca_system_score_gemma":0.000026427013,"threshold_uncertainty_score":0.62708604},"labels":[],"label_agreement":null},{"id":"W4225405746","doi":"10.1096/fasebj.2022.36.s1.r5812","title":"Determining the Requirements for Gαi:β‐arrestin Complex Formation at G Protein‐Coupled Receptors","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"G protein-coupled receptor; Receptor; G protein; G protein-coupled receptor kinase; Arrestin; Rhodopsin-like receptors; Cell biology; 5-HT5A receptor; Chemokine receptor; Chemistry; Biology; Biochemistry; Metabotropic receptor; Agonist; Chemokine","score_opus":0.04451268082324293,"score_gpt":0.27317371327190465,"score_spread":0.2286610324486617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225405746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879884,0.000092351445,0.010500057,0.0003946321,0.00042838042,0.00049231405,0.000013968492,0.0000064013566,0.000083483166],"genre_scores_gemma":[0.9974416,0.000012044598,0.00090284785,0.000355268,0.00037819913,0.000114131304,0.00009781867,0.000019584822,0.00067852397],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989808,0.0001684397,0.00025069472,0.0001213099,0.00024256241,0.00023619152],"domain_scores_gemma":[0.9994283,0.00002299451,0.0002481778,0.00017935978,0.00007333735,0.00004788457],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0010228475,0.000106411026,0.00008600318,0.000022377875,0.001761011,0.00006234652,0.00036097984,0.000029674597,0.00043079673],"category_scores_gemma":[0.00007480287,0.00006521407,0.00011812703,0.000052622418,0.00003225714,0.0000075266917,0.00019969046,0.0001581397,0.000003528196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012920098,0.000016045655,0.000107409374,0.0000042982665,0.000026052609,5.581717e-7,0.00017537478,0.000521473,0.99399185,0.000032148015,0.002869282,0.0021262825],"study_design_scores_gemma":[0.0012527969,0.0006756587,0.00011406132,0.000014131596,0.000034185425,0.00011990495,0.00079185184,0.006058579,0.94311273,0.0004000856,0.047245294,0.0001806918],"about_ca_topic_score_codex":0.0000020530817,"about_ca_topic_score_gemma":0.0000034481955,"teacher_disagreement_score":0.050879113,"about_ca_system_score_codex":0.00006497786,"about_ca_system_score_gemma":0.00004060473,"threshold_uncertainty_score":0.99953854},"labels":[],"label_agreement":null},{"id":"W4225410211","doi":"10.1096/fasebj.2022.36.s1.r3126","title":"Nuclear Location Bias of HCAR1 Drives Cancer Malignancy by Multiple Routes","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Nuclear localization sequence; Cell biology; Phosphorylation; Biology; Nuclear transport; Interactome; Cancer cell; Nuclear protein; G protein-coupled receptor; Cancer research; Protein kinase B; Cancer; Chemistry; Transcription factor; Signal transduction; Cell nucleus; Gene; Biochemistry; Genetics; Cytoplasm","score_opus":0.015088332837236863,"score_gpt":0.23281876012101718,"score_spread":0.2177304272837803,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225410211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99521405,0.0029596959,0.001220749,0.00019822051,0.00024647728,0.0000618346,0.000033866785,0.0000032952066,0.00006179484],"genre_scores_gemma":[0.998677,0.0004073654,0.00016943771,0.0001645617,0.00015865822,0.000007682266,0.000018866114,0.000015089966,0.00038131842],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99933857,0.00011708764,0.00016780064,0.0000975067,0.00015573531,0.00012332064],"domain_scores_gemma":[0.99959666,0.000011086311,0.00016869303,0.00012426154,0.00006233514,0.000036980946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028602857,0.000070388596,0.00008023239,0.000019357249,0.00029513438,0.000020103085,0.0002191208,0.000027863625,0.0005377246],"category_scores_gemma":[0.00002776542,0.000051729457,0.000072062394,0.00006429654,0.000029912311,0.0000033480333,0.000084988904,0.00012877455,0.0000015305823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041619463,0.00002644906,0.001205027,0.0000035427945,0.0000407437,8.4177145e-7,0.00022819488,0.0018940838,0.9919652,0.000056642475,0.0026471333,0.0018905747],"study_design_scores_gemma":[0.0002920557,0.00018550584,0.0001683613,0.000012161632,0.0000170659,0.000036591613,0.00090163935,0.00048360968,0.98883426,0.00009436707,0.008893429,0.00008097452],"about_ca_topic_score_codex":0.000048663154,"about_ca_topic_score_gemma":0.000004713836,"teacher_disagreement_score":0.0062462958,"about_ca_system_score_codex":0.0000170525,"about_ca_system_score_gemma":0.000051819996,"threshold_uncertainty_score":0.5887707},"labels":[],"label_agreement":null},{"id":"W4226036102","doi":"10.7554/elife.73901","title":"Allosteric modulation of the adenosine A2A receptor by cholesterol","year":2021,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University; University of Toronto","funders":"Japan Science and Technology Agency; Canadian Institutes of Health Research","keywords":"Allosteric regulation; Biophysics; Cholesterol; Chemistry; Allosteric enzyme; Phospholipid; Biochemistry; Membrane fluidity; Nuclear magnetic resonance spectroscopy; Receptor; Stereochemistry; Membrane; Biology","score_opus":0.005999629980910286,"score_gpt":0.21094428781258154,"score_spread":0.20494465783167126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4226036102","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965408,0.00073234335,0.0018421586,0.00034401132,0.00026881442,0.00006450177,0.000018138779,0.0000039364736,0.00018533377],"genre_scores_gemma":[0.99717146,0.00010662382,0.0004716669,0.00045927562,0.00014110412,0.0000047637054,0.00009943456,0.000011547183,0.00153412],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99944705,0.000046264195,0.00013460456,0.00015504182,0.00012736523,0.00008965311],"domain_scores_gemma":[0.9995967,0.0000031632426,0.00006515479,0.0002256963,0.000081792285,0.000027508207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006997342,0.00006680141,0.00007547956,0.00000611558,0.000037239817,0.00001076145,0.00009954901,0.000073845054,0.0001504297],"category_scores_gemma":[0.000038994334,0.000051790572,0.00006355572,0.000062055144,0.000016945045,0.0000020519285,0.00007454448,0.000040341165,0.0000062328636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006934431,0.000022114578,0.00055120443,0.0000057442408,0.000014013478,9.310327e-8,0.000022013088,0.000051485924,0.992422,0.00001953335,0.0058537154,0.0010311641],"study_design_scores_gemma":[0.00018040536,0.00003930294,0.0013681144,0.000012227354,0.0000051459824,0.0000022982747,0.000025368214,0.000065718516,0.9508756,0.000006577022,0.04736054,0.000058742553],"about_ca_topic_score_codex":0.0000045544302,"about_ca_topic_score_gemma":0.0000027301303,"teacher_disagreement_score":0.041546423,"about_ca_system_score_codex":0.0000049505347,"about_ca_system_score_gemma":0.00002906883,"threshold_uncertainty_score":0.21119583},"labels":[],"label_agreement":null},{"id":"W4229441147","doi":"10.1038/s41467-022-29609-6","title":"The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":116,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research; European Commission; Hessisches Ministerium für Wissenschaft und Kunst; Deutsche Forschungsgemeinschaft; American Heart Association","keywords":"Allosteric regulation; G protein-coupled receptor; Receptor; Binding site; In silico; Chemistry; Docking (animal); Drug discovery; Computational biology; Biophysics; Biology; Biochemistry; Medicine","score_opus":0.013281638240039662,"score_gpt":0.2687985248168804,"score_spread":0.25551688657684074,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229441147","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9562412,0.040590446,0.00007114265,0.0016034014,0.00024293252,0.0005822561,0.000046996443,0.000022988293,0.00059865805],"genre_scores_gemma":[0.99450094,0.0010827444,0.0025363604,0.0002392169,0.000039779497,0.0001701148,0.00051859824,0.000020721043,0.0008915374],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989036,0.00031415166,0.0002612235,0.00017148066,0.00017658064,0.00017300497],"domain_scores_gemma":[0.99811924,0.00007245072,0.00019433878,0.0014301848,0.00014357595,0.00004019147],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005583259,0.000106410145,0.00012329296,0.000034844987,0.0007224563,0.000019437897,0.001296723,0.00012455927,0.00014440606],"category_scores_gemma":[0.00017851435,0.00008684211,0.000084881125,0.000231185,0.000082989034,0.0000031058703,0.00084714155,0.00046166155,0.0000027706456],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003204117,0.000049219663,0.0002909165,0.0000048413995,0.00005360418,1.1046088e-7,0.00007935624,0.00002175619,0.99461734,0.0014472146,0.0027663053,0.00063728244],"study_design_scores_gemma":[0.00055392814,0.0006589367,0.0005914571,0.000021303897,0.000055469493,0.000014439014,0.0008992594,0.0003910146,0.29597858,0.0011240783,0.6993174,0.00039416816],"about_ca_topic_score_codex":0.000014049422,"about_ca_topic_score_gemma":0.000059381808,"teacher_disagreement_score":0.6986388,"about_ca_system_score_codex":0.00002568483,"about_ca_system_score_gemma":0.00006317194,"threshold_uncertainty_score":0.5556623},"labels":[],"label_agreement":null},{"id":"W4230040793","doi":"10.1016/j.bpj.2017.11.716","title":"Functional Validation of Heteromeric Kainate Receptor Models","year":2018,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Engineering and Physical Sciences Research Council; Medical Research Council","keywords":"Homomeric; Kainate receptor; Biophysics; Chemistry; Ion channel; Gating; Receptor; Dimer; Xenopus; Molecular dynamics; Biochemistry; Biology; Glutamate receptor; AMPA receptor; Protein subunit; Computational chemistry","score_opus":0.01980017745609683,"score_gpt":0.2425231899921552,"score_spread":0.22272301253605836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4230040793","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92432344,0.000021767835,0.074866,0.000048944818,0.00043907715,0.00003548256,0.0000054228663,0.000004106781,0.00025577948],"genre_scores_gemma":[0.99626595,0.000032120086,0.001786796,0.00005836806,0.0016413211,0.0000019412623,0.00002379028,0.000012197763,0.00017752244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930865,0.000045952114,0.00018799088,0.00014231117,0.00017461757,0.00014050637],"domain_scores_gemma":[0.9994843,0.000004737671,0.00012457366,0.00010446005,0.00020467327,0.000077235665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012772102,0.00008773122,0.00010644793,0.0000330599,0.00009302607,0.000021981989,0.00010001457,0.00006912465,0.00027999206],"category_scores_gemma":[0.000015884752,0.00007325855,0.00012118189,0.00007105375,0.00007219167,0.000009362181,0.000036714133,0.00007684823,0.000027991759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008516388,0.00005198419,0.000014543267,0.0000028876739,0.00003277969,3.2439212e-7,0.000019588313,0.000162475,0.99687284,0.0003461848,0.0010170365,0.0013942121],"study_design_scores_gemma":[0.00025726564,0.00057553715,0.00007865513,0.000009734977,0.000009227959,0.000017003635,0.000018580267,0.00060181954,0.9961461,0.0007888384,0.0014073815,0.00008988045],"about_ca_topic_score_codex":0.0000016426401,"about_ca_topic_score_gemma":8.757472e-8,"teacher_disagreement_score":0.0730792,"about_ca_system_score_codex":0.000009870257,"about_ca_system_score_gemma":0.00003411063,"threshold_uncertainty_score":0.30657166},"labels":[],"label_agreement":null},{"id":"W4230078004","doi":"10.1211/cp.2016.20202124","title":"Heart failure drugs might reduce Herceptin cardiac risk","year":2016,"lang":"en","type":"article","venue":"Clinical pharmacist","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Heart failure; Medicine; Trastuzumab; Intensive care medicine; Internal medicine; Pharmacology; Cancer; Breast cancer","score_opus":0.03212208990934061,"score_gpt":0.35940130184808844,"score_spread":0.3272792119387478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4230078004","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99447143,0.00050232024,0.0013556539,0.0011296589,0.0014762365,0.0001927334,0.00009629936,0.000037554997,0.0007381025],"genre_scores_gemma":[0.99124557,0.0008185257,0.0015933195,0.0006682196,0.0022509494,0.000020263518,0.00003322659,0.000039813873,0.0033300845],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99808484,0.00035171187,0.0004883433,0.00058433367,0.00016322515,0.0003275255],"domain_scores_gemma":[0.9989786,0.00010861558,0.00013687045,0.0004240547,0.00008803651,0.00026383752],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009796207,0.00019521889,0.0002932556,0.000019396015,0.00011818915,0.000026345266,0.0002508514,0.00022969778,0.0008264283],"category_scores_gemma":[0.00028228736,0.00013484142,0.00044278172,0.000059750055,0.00015539544,0.000005661301,0.00012558316,0.00020369388,0.0004917125],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012692422,0.000067279994,0.006231565,0.0000049962896,0.000076771736,0.0000014614421,0.000014746029,0.0000013591562,0.8373402,0.000017101815,0.13755062,0.018566988],"study_design_scores_gemma":[0.0008797839,0.00013915084,0.00029817517,0.0000139878575,0.000033384596,0.0000025258094,0.000021247011,0.0000067715264,0.3926503,0.000101137775,0.60565215,0.00020139643],"about_ca_topic_score_codex":0.000005386753,"about_ca_topic_score_gemma":0.0000010623573,"teacher_disagreement_score":0.4681015,"about_ca_system_score_codex":0.0000130037715,"about_ca_system_score_gemma":0.00006003937,"threshold_uncertainty_score":0.90488106},"labels":[],"label_agreement":null},{"id":"W4230449127","doi":"10.2142/biophys.45.s104_2","title":"1P290 Prediction of interfaces for oligomerizations of G-protein coupled receptors","year":2005,"lang":"en","type":"article","venue":"Seibutsu Butsuri","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Northern Alberta Institute of Technology","funders":"","keywords":"Receptor; Chemistry; Biophysics; Biology; Biochemistry","score_opus":0.011565375433193902,"score_gpt":0.23622887097612855,"score_spread":0.22466349554293463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4230449127","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9266877,0.0003985673,0.07172996,0.000118783486,0.00021134743,0.0003784838,0.00021597414,0.000014009398,0.0002451675],"genre_scores_gemma":[0.99189,0.000087719956,0.0065540625,0.000022362587,0.00021153144,0.000043052023,0.0003192649,0.000020561927,0.0008514588],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991638,0.000026468118,0.00034087372,0.00020589955,0.000109953784,0.00015299238],"domain_scores_gemma":[0.9993591,0.000011532486,0.00017917418,0.0002069792,0.00020088418,0.000042360767],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020066192,0.000111811474,0.00017668554,0.000051699815,0.00004511931,0.000006649146,0.00013551564,0.0001269304,0.0001355714],"category_scores_gemma":[0.00008480822,0.0001087596,0.00009877353,0.00009049884,0.000050851966,0.000006916608,0.00003180833,0.00003899194,0.000002227059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007279427,0.000059309205,0.00015284024,0.000038987044,0.000052579322,2.3318973e-8,0.0000719258,0.0005878415,0.9962539,0.00035090037,0.00036391112,0.001994962],"study_design_scores_gemma":[0.00044581556,0.00046622448,0.000039306993,0.000033712684,0.000019317877,8.289515e-7,0.00009638088,0.001252667,0.9759387,0.00010800208,0.021510225,0.00008885837],"about_ca_topic_score_codex":0.000015612102,"about_ca_topic_score_gemma":0.000008694521,"teacher_disagreement_score":0.06520228,"about_ca_system_score_codex":0.000009662029,"about_ca_system_score_gemma":0.000048431106,"threshold_uncertainty_score":0.4435088},"labels":[],"label_agreement":null},{"id":"W4230559387","doi":"10.1139/y01-044","title":"Metabolism of angiotensin I by guinea pig aqueous humor","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"American Heart Association","keywords":"Chemistry; Angiotensin II; Guinea pig; Renin–angiotensin system; Enzyme; Angiotensin-converting enzyme; Chromatography; Trifluoroacetic acid; Enalaprilat; Biochemistry; Endocrinology; ACE inhibitor; Biology; Receptor","score_opus":0.0076727466773147245,"score_gpt":0.23854703988334175,"score_spread":0.23087429320602704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4230559387","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98865706,0.009832569,0.00018461826,0.0004087983,0.0007235435,0.000054986955,0.000025964899,0.0000011275766,0.000111313806],"genre_scores_gemma":[0.9971265,0.0008960656,0.00023718485,0.0010177837,0.00052290736,0.0000013180834,0.000017941189,0.0000116987085,0.00016858654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916804,0.00012170326,0.00027227233,0.00014261207,0.00003748823,0.00025790813],"domain_scores_gemma":[0.9992706,0.00001821794,0.00019999265,0.00007611972,0.0001549819,0.00028009567],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00017905526,0.00011762277,0.00028189577,0.000093576986,0.00007503891,0.000003914301,0.00015449514,0.00016866953,0.0012173777],"category_scores_gemma":[0.000021858012,0.00010563985,0.00009421532,0.00006160136,0.00018340239,0.000004949931,0.000016914246,0.00014676887,0.0000016144215],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009991111,0.000015585965,0.00015394637,0.000007371458,0.00012943635,0.00002981936,0.000054812062,0.0000355109,0.978566,0.000053186603,0.019721566,0.0011328915],"study_design_scores_gemma":[0.00062199746,0.0003530049,0.00034098307,0.0000041857893,0.00006132663,0.00026640372,0.00003111182,0.000017386834,0.8592653,0.00037553217,0.13856307,0.00009965344],"about_ca_topic_score_codex":0.00028128113,"about_ca_topic_score_gemma":0.0001621518,"teacher_disagreement_score":0.11930061,"about_ca_system_score_codex":0.000008011686,"about_ca_system_score_gemma":0.00025022146,"threshold_uncertainty_score":0.99969566},"labels":[],"label_agreement":null},{"id":"W4230686950","doi":"10.1007/s00335-001-2138-3","title":"Congenic mapping of a blood pressure QTL on Chromosome 16 of Dahl rats","year":2002,"lang":"en","type":"article","venue":"Mammalian Genome","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Congenic; Quantitative trait locus; Biology; Genetics; Locus (genetics); Chromosome; Homologous chromosome; Genetic linkage; Chromosomal region; Strain (injury); Gene; Anatomy","score_opus":0.01577496617227968,"score_gpt":0.2066437129097052,"score_spread":0.19086874673742552,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4230686950","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9898351,0.0057955254,0.0002540656,0.000043609318,0.0001295371,0.0002187021,0.000076686236,0.000009210441,0.003637571],"genre_scores_gemma":[0.9936032,0.00016066978,0.0004103286,0.00006911528,0.00017591019,0.000010948498,0.000044592816,0.000025527093,0.005499684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989619,0.000047526606,0.00031240843,0.00029691053,0.0001526911,0.00022855234],"domain_scores_gemma":[0.99929357,0.000007027617,0.0001726594,0.0003878293,0.0000677458,0.000071150425],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00013118809,0.0001561037,0.00023868847,0.00006205713,0.000038282054,0.000008835206,0.00022767585,0.00014860585,0.0015947699],"category_scores_gemma":[0.000020286981,0.00015127959,0.00014234692,0.00009630281,0.000051371066,0.0000027312806,0.00006914344,0.00007161474,0.000017266897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021753842,0.00009917346,0.00008795783,0.000081401304,0.00024293883,0.000003759019,0.00013041473,0.000094610616,0.99835616,0.000118992226,0.00021536129,0.0005474465],"study_design_scores_gemma":[0.0005033871,0.00057343504,0.00018252154,0.000031019106,0.0001095995,0.00000952527,0.00005995466,0.000037327485,0.9640018,0.000039557268,0.034271598,0.00018029672],"about_ca_topic_score_codex":0.000009905041,"about_ca_topic_score_gemma":0.0000024466271,"teacher_disagreement_score":0.03435441,"about_ca_system_score_codex":0.000003988673,"about_ca_system_score_gemma":0.000015167948,"threshold_uncertainty_score":0.9993179},"labels":[],"label_agreement":null},{"id":"W4232689631","doi":"10.36866/pn.84.14","title":"The orderly recruitment of postganglionic sympathetic neurons","year":2011,"lang":"en","type":"article","venue":"Physiology News","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Academy of Medical Sciences","keywords":"Neuroscience; Psychology; Business","score_opus":0.04848246267393007,"score_gpt":0.2594634744749317,"score_spread":0.2109810118010016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4232689631","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972064,0.00074497954,0.00021446736,0.0000659866,0.00029603744,0.00021378524,0.0000036518247,0.000007494501,0.0012472284],"genre_scores_gemma":[0.9987215,0.0004276394,0.00027481923,0.00015979134,0.000075299,0.000042087187,0.0000133022695,0.0000138234545,0.00027176604],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930096,0.00009231002,0.00016712314,0.0002007885,0.000047449223,0.00019136297],"domain_scores_gemma":[0.99946713,0.000014988629,0.00009171737,0.0003433686,0.000047255602,0.000035551733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009186784,0.00009870454,0.000111981135,0.000014561438,0.00009351619,0.0000035579037,0.0002172524,0.000075885815,0.00006480742],"category_scores_gemma":[0.000025542526,0.000065463726,0.0000925949,0.000045190387,0.000091873604,0.000001406285,0.000076925426,0.000059014717,0.000016107517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000504285,0.000043085543,0.000053565054,0.000002964847,0.000029720803,4.913482e-7,0.00010510495,0.000004591175,0.99311507,0.0019952764,0.00021911623,0.00438061],"study_design_scores_gemma":[0.00025440543,0.0009586688,0.0014249068,0.0000055278274,0.000017775441,0.0000067560763,0.00018124422,0.000021359694,0.9705468,0.003628416,0.022835802,0.000118347365],"about_ca_topic_score_codex":0.000035999423,"about_ca_topic_score_gemma":0.000018007915,"teacher_disagreement_score":0.022616684,"about_ca_system_score_codex":0.0000034713225,"about_ca_system_score_gemma":0.000033675013,"threshold_uncertainty_score":0.26695335},"labels":[],"label_agreement":null},{"id":"W4233307823","doi":"10.1523/jneurosci.2120-16.2017","title":"Nonlinear Y-Like Receptive Fields in the Early Visual Cortex: An Intermediate Stage for Building Cue-Invariant Receptive Fields from Subcortical Y Cells","year":2017,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Nvidia","keywords":"Receptive field; Visual cortex; Spatial frequency; Surround suppression; Luminance; Neuroscience; Contrast (vision); Invariant (physics); Orientation column; Physics; Orientation (vector space); Psychology; Optics; Visual perception; Mathematics; Geometry; Striate cortex; Perception","score_opus":0.027750739880400655,"score_gpt":0.32008407426901764,"score_spread":0.29233333438861697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233307823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96052,0.000023371667,0.037659474,0.00020164602,0.0013994789,0.0001465549,0.000024230998,0.0000019808417,0.000023240875],"genre_scores_gemma":[0.995865,0.00014377272,0.0026106504,0.0007340297,0.0005530571,0.0000045661313,0.0000027513615,0.000011654952,0.00007450521],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867773,0.00012006326,0.00036956495,0.00030596327,0.0002600696,0.00026662654],"domain_scores_gemma":[0.99896073,0.00008194028,0.00041654258,0.00030373916,0.00012554027,0.00011152271],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067526987,0.00013680151,0.00019551799,0.000047930065,0.00024562888,0.00022878923,0.00087888626,0.00013953292,0.00001655261],"category_scores_gemma":[0.00044563788,0.00009676805,0.00012718237,0.000049255817,0.00014745511,0.000053456544,0.00011814245,0.00032531022,7.674413e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021582334,0.00009489832,0.00047604705,0.0000028133113,0.000005045658,0.000038351252,0.00040372324,0.00006261313,0.997364,0.000030996234,0.00008638221,0.0012193343],"study_design_scores_gemma":[0.0014110865,0.007568796,0.030148316,0.000088195506,0.000037586953,0.000039395185,0.0009162447,0.008571047,0.94705516,0.0004681167,0.0033323788,0.0003636626],"about_ca_topic_score_codex":0.000050934243,"about_ca_topic_score_gemma":0.000060298597,"teacher_disagreement_score":0.050308798,"about_ca_system_score_codex":0.000011897611,"about_ca_system_score_gemma":0.00009653108,"threshold_uncertainty_score":0.39460868},"labels":[],"label_agreement":null},{"id":"W4233579705","doi":"10.3410/f.3334972.3023071","title":"Faculty Opinions recommendation of The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation.","year":2010,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal","funders":"","keywords":"Domain (mathematical analysis); Computer science; Mathematics","score_opus":0.014618320648208208,"score_gpt":0.30058077697611485,"score_spread":0.2859624563279066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233579705","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00005681111,0.00082349457,0.00004656309,0.08022097,0.0005166996,0.0017169857,0.9165806,0.000010875014,0.00002699344],"genre_scores_gemma":[0.00007705065,0.0002817297,0.0011882576,0.0018934992,0.00038274738,0.00031057696,0.99464613,0.000026367696,0.0011936561],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9969876,0.00038587718,0.000988251,0.0006090139,0.00076313235,0.00026613884],"domain_scores_gemma":[0.9948876,0.000045241915,0.0012444983,0.0012878312,0.0023678553,0.00016699954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00093622226,0.0004215133,0.000551411,0.00012452061,0.00025078232,0.00011824437,0.0011785801,0.0009709639,0.00024216904],"category_scores_gemma":[0.003920061,0.00024218718,0.00044010582,0.0007498305,0.00032295476,0.00003723919,0.0005962946,0.0008656936,0.00000478731],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000140117045,0.00013089748,0.0000020534328,0.001624347,0.00008761754,3.719307e-8,0.000031552634,6.763509e-8,0.0047035287,0.0002210048,0.9913895,0.0017953576],"study_design_scores_gemma":[0.0004081367,0.00009980187,0.00024350155,0.00392716,0.000071765484,0.000017701565,0.00001943514,0.0000022748102,0.007516442,0.000076938246,0.98735297,0.00026389322],"about_ca_topic_score_codex":0.00004037994,"about_ca_topic_score_gemma":0.000009198685,"teacher_disagreement_score":0.07832747,"about_ca_system_score_codex":0.00002989067,"about_ca_system_score_gemma":0.00033502377,"threshold_uncertainty_score":0.98761064},"labels":[],"label_agreement":null},{"id":"W4234923223","doi":"10.3410/f.1159737.621143","title":"Faculty Opinions recommendation of beta-Adrenergic agonists increase phosphorylation of elongation factor 2 in cardiomyocytes without eliciting calcium-independent eEF2 kinase activity.","year":2009,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"BETA (programming language); Phosphorylation; Calcium; Elongation factor; Chemistry; Adrenergic receptor; Kinase; Internal medicine; Endocrinology; Pharmacology; Cell biology; Biology; Biochemistry; Computer science; Medicine; Receptor; Gene","score_opus":0.026604987147368885,"score_gpt":0.33453170339286664,"score_spread":0.3079267162454978,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4234923223","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010883023,0.0011533186,0.00032138117,0.006714239,0.00038157828,0.0011194417,0.9891858,0.000011942381,0.000023986655],"genre_scores_gemma":[0.014709197,0.00036418624,0.0005557272,0.00043485066,0.00023412504,0.000107778826,0.98345685,0.00002628745,0.00011097954],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99586415,0.00058737333,0.001468121,0.00069146993,0.0010780736,0.00031078063],"domain_scores_gemma":[0.99394584,0.00005532261,0.0019439692,0.00097613625,0.002887939,0.00019080336],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012689221,0.00049415365,0.0009769825,0.0003254535,0.00013563676,0.00006754865,0.0007947463,0.00083495124,0.00013434843],"category_scores_gemma":[0.0024216091,0.0003711928,0.0006133484,0.0009540483,0.00014050631,0.000056945843,0.00027412386,0.0006060729,0.0000031232444],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000078365854,0.00045289195,0.00006398342,0.0029882686,0.00019168324,3.7594313e-7,0.00008344911,0.00000842731,0.005768187,0.00006290568,0.9815094,0.00879207],"study_design_scores_gemma":[0.000877965,0.00024560778,0.0038054292,0.004224117,0.00015538724,0.000013222626,0.00002720238,0.000037778027,0.03406653,0.000016656493,0.95614606,0.00038403188],"about_ca_topic_score_codex":0.00030401742,"about_ca_topic_score_gemma":0.000028148583,"teacher_disagreement_score":0.028298346,"about_ca_system_score_codex":0.00011078305,"about_ca_system_score_gemma":0.00047507428,"threshold_uncertainty_score":0.999874},"labels":[],"label_agreement":null},{"id":"W4235938548","doi":"10.1139/cjpp-78-5-407","title":"Predictors of &lt;i&gt;Torsades de Pointes &lt;/i&gt;in rabbit ventricles perfused with sedating and nonsedating histamine H&lt;sub&gt;1&lt;/sub&gt;-receptor antagonists","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Torsades de pointes; Histamine; Medicine; Anesthesia; Internal medicine; Pharmacology; Endocrinology; Cardiology; QT interval","score_opus":0.005151842317964896,"score_gpt":0.21379036514028113,"score_spread":0.20863852282231624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4235938548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948478,0.0041983332,0.00006547772,0.00019921098,0.0003241152,0.00018194637,0.00008776371,0.000005379092,0.00009002475],"genre_scores_gemma":[0.9969398,0.0014615689,0.000590121,0.00029564332,0.0005367034,0.0000092214,0.00006110605,0.000036528007,0.0000693276],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99793506,0.00035881292,0.00059747894,0.00038262398,0.00010620054,0.000619799],"domain_scores_gemma":[0.99870545,0.00012994076,0.00038856058,0.00012859904,0.0001633942,0.0004840684],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000544153,0.0003061605,0.00055211183,0.00024163804,0.0002292081,0.00002150567,0.00024322531,0.0002956373,0.0011338026],"category_scores_gemma":[0.00006947638,0.00027955842,0.000103608334,0.0001619079,0.00045536296,0.000028357734,0.000034790242,0.00031180197,0.0000019489523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049108564,0.000057281228,0.0044058417,0.0000886272,0.00020922913,0.000060621827,0.0004249216,0.00031984455,0.9905555,0.000050262213,0.0013064384,0.0020303053],"study_design_scores_gemma":[0.0022652317,0.001362523,0.0046593905,0.0001044686,0.00012293784,0.00027079653,0.00008161348,0.00029499218,0.97914636,0.00007260676,0.011312379,0.0003066717],"about_ca_topic_score_codex":0.000084855295,"about_ca_topic_score_gemma":0.0009820376,"teacher_disagreement_score":0.011409151,"about_ca_system_score_codex":0.00007544602,"about_ca_system_score_gemma":0.0006710094,"threshold_uncertainty_score":0.99996567},"labels":[],"label_agreement":null},{"id":"W4236745920","doi":"10.1139/y00-045","title":"The negative inotropic action of catecholamines: Role of β<sub>3</sub>-adrenoceptors","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"GIS-Institut des Maladies Rares; Fédération Wallonie-Bruxelles","keywords":"Inotrope; Contractility; Stimulation; Adrenergic receptor; Internal medicine; Heart failure; Endocrinology; Adrenergic; Receptor; Biology; Medicine","score_opus":0.006745809143754599,"score_gpt":0.23265722172249623,"score_spread":0.22591141257874162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4236745920","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978042,0.0016387617,0.0000146689235,0.00007727357,0.00032924072,0.00006183038,0.000014400421,6.862961e-7,0.000058927268],"genre_scores_gemma":[0.9981789,0.0013996408,0.000041897005,0.000100139696,0.00023726764,0.0000024013887,0.0000054276516,0.0000074008503,0.000026954283],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992467,0.0001404526,0.00029476994,0.00010212441,0.000037398797,0.00017855834],"domain_scores_gemma":[0.9993793,0.000044107543,0.0002452771,0.00006704818,0.00013785783,0.00012642871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015421167,0.000091657,0.00018988535,0.00005864436,0.000116544885,0.0000031991406,0.00014608227,0.00013622934,0.0004959186],"category_scores_gemma":[0.000021289528,0.00006962413,0.00007450465,0.000062428575,0.00027978356,0.0000066053913,0.000009275901,0.00015543822,0.0000010571998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015286454,0.000010631458,0.0001853013,0.000012594909,0.00011256955,0.0000013499046,0.00013964038,0.00013574559,0.9876372,0.000044307082,0.00041153686,0.011156241],"study_design_scores_gemma":[0.00039458292,0.0005027291,0.0010893164,0.0000064972864,0.000038381706,0.000027831487,0.00016593805,0.0000191914,0.9898257,0.0009822507,0.006886941,0.000060608752],"about_ca_topic_score_codex":0.00019277046,"about_ca_topic_score_gemma":0.0007478979,"teacher_disagreement_score":0.011095633,"about_ca_system_score_codex":0.000012064501,"about_ca_system_score_gemma":0.00026699412,"threshold_uncertainty_score":0.5429961},"labels":[],"label_agreement":null},{"id":"W4238253485","doi":"10.1007/978-1-4614-6438-9_101765-1","title":"GRK2 (G Protein-Coupled Receptor Kinase 2)","year":2016,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Beta adrenergic receptor kinase; G protein-coupled receptor kinase; Pharmacology; Receptor; Medicine; Internal medicine; G protein-coupled receptor","score_opus":0.010255816628421217,"score_gpt":0.21221125382834308,"score_spread":0.20195543719992187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4238253485","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0027019167,0.0014636439,0.008191755,0.00020498654,0.00072706357,0.0009627945,0.000103095124,0.000075867894,0.9855689],"genre_scores_gemma":[0.0053563253,0.00032881214,0.0017957886,0.00022524272,0.0013362963,0.00004525136,0.00021501658,0.00013341737,0.99056387],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99847794,0.000013339528,0.00032040596,0.00066208025,0.0002216219,0.00030463512],"domain_scores_gemma":[0.9989541,0.0000060226466,0.0001754265,0.00057639397,0.0001360059,0.00015202518],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00015702918,0.00042341126,0.0003137063,0.000058471778,0.00007736153,0.000031011103,0.00027753753,0.0007342681,0.013670162],"category_scores_gemma":[0.000025343457,0.00031536905,0.00028714907,0.00000943044,0.00005716302,0.000002177742,0.00015804407,0.00015669914,0.0007592039],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056180095,0.000009189768,3.6225367e-7,0.00002261005,0.00008986765,0.0000047324247,0.000003366659,2.49209e-7,0.9375992,0.05146488,0.0058877906,0.00486159],"study_design_scores_gemma":[0.000288862,0.00022502508,1.0563341e-7,0.00011232664,0.000016447519,0.0000035935184,0.0000027720773,0.0000022348925,0.4176392,0.0035851272,0.57770056,0.00042374423],"about_ca_topic_score_codex":0.000003510774,"about_ca_topic_score_gemma":0.000007799837,"teacher_disagreement_score":0.57181275,"about_ca_system_score_codex":0.000026151669,"about_ca_system_score_gemma":0.000109413864,"threshold_uncertainty_score":0.99992985},"labels":[],"label_agreement":null},{"id":"W4239073488","doi":"10.31219/osf.io/uz54a","title":"Sensitivity analysis of a smooth muscle cell electrophysiological model.","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Lawson Health Research Institute; Western University","funders":"Compute Canada; Canarie","keywords":"Sensitivity (control systems); Biological system; Computer science; Mathematical model; Model validation; Linear model; Experimental data; Neuroscience; Biochemical engineering; Mathematics; Machine learning; Biology; Engineering; Electronic engineering; Statistics","score_opus":0.012687008311462388,"score_gpt":0.23786741402552644,"score_spread":0.22518040571406406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239073488","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.80684346,0.0002582546,0.19184893,0.000008816581,0.000050189592,0.000082319624,0.00003575457,0.000009335415,0.0008629415],"genre_scores_gemma":[0.988186,0.00033097196,0.010089122,0.000109574394,0.00006560721,0.000010062419,0.0009168383,0.000016488542,0.00027535396],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985633,0.00013810188,0.00027090276,0.0006590993,0.00015104513,0.00021753726],"domain_scores_gemma":[0.9990238,0.00001215477,0.00016167217,0.00056371395,0.00017342022,0.00006522048],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020779291,0.00022627087,0.0005441182,0.00008383664,0.000030330746,0.000024671675,0.00013996103,0.00048127185,0.00021401401],"category_scores_gemma":[0.00002650117,0.00019785845,0.00069122657,0.00016942997,0.000033323755,9.221137e-7,0.00056202686,0.00022115171,6.6903084e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002117889,0.00008588436,0.000015354286,0.000024083594,0.0003487496,0.0000033974618,0.000014552524,0.1718533,0.8272857,0.00003248241,0.000039119244,0.00027621567],"study_design_scores_gemma":[0.00008283351,0.00010256751,0.00033483945,0.000006758431,0.00047406688,2.3369931e-7,0.000041720785,0.15914504,0.8394111,0.00011821588,0.000046354508,0.00023628073],"about_ca_topic_score_codex":0.00012325517,"about_ca_topic_score_gemma":0.00006674323,"teacher_disagreement_score":0.1817598,"about_ca_system_score_codex":0.00001252446,"about_ca_system_score_gemma":0.00014185993,"threshold_uncertainty_score":0.80684334},"labels":[],"label_agreement":null},{"id":"W4239625085","doi":"10.3410/f.1163168.623843","title":"Faculty Opinions recommendation of Membrane-tethered ligands are effective probes for exploring class B1 G protein-coupled receptor function.","year":2009,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Class (philosophy); Function (biology); G protein-coupled receptor; Protein function; Chemistry; Computational biology; Receptor; Biophysics; Biochemistry; Computer science; Biology; Cell biology; Artificial intelligence; Gene","score_opus":0.03064611873699102,"score_gpt":0.31521598277474666,"score_spread":0.28456986403775564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239625085","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000029014436,0.0011999232,0.00059743243,0.028264668,0.0010012302,0.0041810055,0.96468943,0.000027212996,0.000010078579],"genre_scores_gemma":[0.0000807037,0.00041352346,0.0010543822,0.0012731806,0.000747863,0.0023139261,0.99340963,0.0000438667,0.0006629327],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964665,0.00028829608,0.0012504008,0.0008443644,0.0007727391,0.0003776854],"domain_scores_gemma":[0.9922922,0.000068912625,0.0016141065,0.0010567849,0.0047522285,0.00021573236],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013300184,0.000576056,0.0009107632,0.00020936756,0.0002808344,0.00010548273,0.0009790877,0.0008639568,0.00017929311],"category_scores_gemma":[0.004180501,0.00039562103,0.000803197,0.0008158996,0.00014281305,0.00005613146,0.00024630225,0.0005938187,0.000009191207],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011417866,0.00029554276,7.5883605e-7,0.005660161,0.00025663333,5.1733792e-8,0.000040584033,9.111546e-7,0.0051683504,0.000087551816,0.9858238,0.0025514746],"study_design_scores_gemma":[0.0009930518,0.00069452974,0.0000642855,0.0078987535,0.00017708453,0.000005251125,0.000050420338,0.000012958483,0.024457188,0.000030809057,0.96522003,0.0003956041],"about_ca_topic_score_codex":0.000014330337,"about_ca_topic_score_gemma":0.000003969256,"teacher_disagreement_score":0.028720187,"about_ca_system_score_codex":0.0000704398,"about_ca_system_score_gemma":0.00029990284,"threshold_uncertainty_score":0.99984956},"labels":[],"label_agreement":null},{"id":"W4242291996","doi":"10.2172/1434450","title":"Mechanistic insights into allosteric regulation of the A&lt;sub&gt;2A&lt;/sub&gt; adenosine G protein-coupled receptor by physiological cations","year":2018,"lang":"en","type":"report","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Los Alamos National Laboratory; National Nuclear Security Administration; U.S. Department of Energy","keywords":"Allosteric regulation; G protein-coupled receptor; Extracellular; Chemistry; Allosteric modulator; Adenosine; Adenosine receptor; Rigidity (electromagnetism); Biophysics; Receptor; Cell biology; Biochemistry; Biology; Physics","score_opus":0.015271621723008055,"score_gpt":0.2420280951118539,"score_spread":0.22675647338884586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242291996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9688409,0.0042565,0.018677182,0.00020197382,0.0020456174,0.0028892425,0.00013571886,0.00008596766,0.0028668866],"genre_scores_gemma":[0.98419654,0.0014320649,0.0017006985,0.00009805012,0.0012675938,0.00031076334,0.0026936787,0.000113418784,0.008187164],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99644333,0.00023418057,0.0009852382,0.0010549403,0.00085988594,0.00042244975],"domain_scores_gemma":[0.9965506,0.000024708464,0.0009832942,0.0011102001,0.0011827325,0.00014845114],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047148147,0.0006235209,0.0007136809,0.00009917492,0.0003205725,0.00005583221,0.00068504206,0.001184584,0.0007205951],"category_scores_gemma":[0.0004412831,0.00042564972,0.00042649359,0.0003091319,0.00022703432,0.000010374032,0.00044910368,0.0002854094,0.000038739283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005831419,0.00014010652,0.000002010403,0.00014696778,0.00015994438,4.5233912e-7,0.000041362637,0.000010614418,0.9690079,0.00030013354,0.029664164,0.00046803578],"study_design_scores_gemma":[0.00030884994,0.0006662036,0.00008740203,0.0002026452,0.0001234644,0.0000075059206,0.000019187251,0.00022141903,0.9345451,0.001031777,0.062246826,0.00053964596],"about_ca_topic_score_codex":0.00008792897,"about_ca_topic_score_gemma":0.0001164645,"teacher_disagreement_score":0.034462817,"about_ca_system_score_codex":0.00015663716,"about_ca_system_score_gemma":0.0006783681,"threshold_uncertainty_score":0.9998195},"labels":[],"label_agreement":null},{"id":"W4242349146","doi":"10.3410/f.1028340.336146","title":"Faculty Opinions recommendation of A hybrid approach to measuring electrical activity in genetically specified neurons.","year":2005,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Förster resonance energy transfer; Fluorescence; Green fluorescent protein; Fluorescent protein; Voltage-sensitive dye; Biophysics; Neuroscience; Premovement neuronal activity; Chemistry; Membrane potential; Computer science; Biology; Gene; Physics; Biochemistry; Optics","score_opus":0.0352385586661147,"score_gpt":0.31813911268935846,"score_spread":0.28290055402324377,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242349146","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000029605526,0.00064794265,0.0010429097,0.027219944,0.00035658336,0.0013065562,0.969294,0.000012014799,0.00009044569],"genre_scores_gemma":[0.00022700339,0.0003601279,0.0025899669,0.002047964,0.00043261718,0.00020309247,0.9938532,0.0000308213,0.0002551744],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99609846,0.00050403335,0.0011376002,0.00086057297,0.0009849174,0.00041440598],"domain_scores_gemma":[0.9959798,0.000041615305,0.00067482836,0.0011219255,0.0018830298,0.0002988102],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012202915,0.00046458186,0.0007620889,0.0003033385,0.00011244215,0.00007989098,0.0012685643,0.0004944163,0.00011074753],"category_scores_gemma":[0.0034749033,0.00034078085,0.00047972685,0.0011652523,0.00011369167,0.000024622012,0.0004997179,0.0008283028,0.000012309005],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045977464,0.0005437415,0.00000164716,0.0011366945,0.000062189676,1.8251804e-7,0.00001725704,0.000003305463,0.0008123713,0.00005234113,0.99224436,0.0050799153],"study_design_scores_gemma":[0.00047470882,0.0002008653,0.0004994758,0.0014825219,0.000055959586,0.000030209783,0.00000464361,0.000038279268,0.0039208345,0.000006213447,0.99295783,0.00032847407],"about_ca_topic_score_codex":0.000025039979,"about_ca_topic_score_gemma":0.000004761721,"teacher_disagreement_score":0.025171978,"about_ca_system_score_codex":0.000086425716,"about_ca_system_score_gemma":0.00040652847,"threshold_uncertainty_score":0.9999044},"labels":[],"label_agreement":null},{"id":"W4242596211","doi":"10.1046/j.1471-4159.2002.01003.x","title":"The cytoplasmic tail of the D1A receptor subtype: identification of specific domains controlling dopamine cellular responsiveness","year":2002,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Dopamine receptor; Dopaminergic; Dopamine; Receptor; Schematic; Neuroscience; Biology; Amino acid; Neurotransmitter; D1-like receptor; Peptide sequence; Cell biology; Biochemistry; Dopamine receptor D1","score_opus":0.009957449015919976,"score_gpt":0.20730022614022986,"score_spread":0.1973427771243099,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242596211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99504167,0.0030253015,0.0011028274,0.00020131005,0.00044906736,0.00007868244,0.000011178797,0.0000015480434,0.00008841463],"genre_scores_gemma":[0.9973962,0.0013930496,0.00009333552,0.000020729698,0.00030329928,0.0000017001177,0.0000030681222,0.00001680615,0.0007718265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998575,0.00011719454,0.0007087453,0.0001484045,0.00030375004,0.00014691622],"domain_scores_gemma":[0.9979939,0.00008943916,0.0010857092,0.00038827493,0.00039400556,0.000048699163],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005237268,0.00012320772,0.00020930392,0.000024434914,0.00011798323,0.000023439903,0.0004964501,0.000106822125,0.000047188718],"category_scores_gemma":[0.00031953066,0.000079718964,0.00024764144,0.0001208154,0.00012185597,0.0000060710286,0.000057437737,0.00019189311,0.0000013267789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022464362,0.000048812526,0.0001164267,0.000027768541,0.00004074196,0.0000028762793,0.000029364552,0.0002078073,0.99838233,0.000019353249,0.00062719994,0.0002726965],"study_design_scores_gemma":[0.0005302443,0.00010820093,0.00018304317,0.000042582426,0.000027605163,0.000051560237,0.0001414166,0.00007102175,0.9871332,0.000039319195,0.011598374,0.000073417155],"about_ca_topic_score_codex":4.679922e-7,"about_ca_topic_score_gemma":2.3879696e-7,"teacher_disagreement_score":0.011249093,"about_ca_system_score_codex":0.000014892984,"about_ca_system_score_gemma":0.000050010163,"threshold_uncertainty_score":0.3250845},"labels":[],"label_agreement":null},{"id":"W4243910563","doi":"10.22541/au.163253223.32597426/v1","title":"International Union of Basic and Clinical Pharmacology. Guidelines for GPCR ligand bias","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Terminology; G protein-coupled receptor; Functional selectivity; Receptor; Drug discovery; Signal transduction; Ligand (biochemistry); Computational biology; Neuroscience; Pharmacology; Biology; Data science; Bioinformatics; Computer science; Cell biology; Biochemistry","score_opus":0.12164398183328835,"score_gpt":0.41442348333761386,"score_spread":0.2927795015043255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243910563","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9433555,0.0011907616,0.050025266,0.0010070194,0.0036662866,0.00028836433,0.000063786705,0.0000076427405,0.0003953993],"genre_scores_gemma":[0.91828805,0.011803835,0.060953457,0.0015132847,0.0038466675,0.000057865927,0.0014615481,0.000045193065,0.0020301181],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99876547,0.0000703182,0.00053523196,0.0004359679,0.00008806975,0.00010493926],"domain_scores_gemma":[0.9988668,0.00004117455,0.00021213958,0.00016494749,0.0006605022,0.000054441807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071248296,0.00014846602,0.0002671558,0.00003560844,0.000022792896,0.000026651613,0.00018049743,0.00039355733,0.00015358071],"category_scores_gemma":[0.00028437088,0.00013186771,0.0002152974,0.000016685719,0.00004806148,0.0000015480547,0.00052011805,0.00012382313,2.8127369e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089339,0.00008594504,0.0010820822,0.00008998654,0.00046968966,0.0000012835234,0.000014550155,0.00014468179,0.96695954,0.000063232736,0.017672412,0.013327257],"study_design_scores_gemma":[0.00084062526,0.00019586476,0.00013169371,0.00006350679,0.00009133892,0.0000051000166,0.0001037004,0.0021800476,0.9416331,0.00015314238,0.05440975,0.0001921525],"about_ca_topic_score_codex":0.000019455852,"about_ca_topic_score_gemma":0.000011940559,"teacher_disagreement_score":0.036737338,"about_ca_system_score_codex":0.000004990804,"about_ca_system_score_gemma":0.00012329232,"threshold_uncertainty_score":0.53774095},"labels":[],"label_agreement":null},{"id":"W4243989774","doi":"10.1139/y01-017","title":"Antiproliferative effect of brief exposure to cholera toxin in vascular smooth muscle cells: role of cAMP and protein kinase A","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Cholera toxin; Vascular smooth muscle; Protein kinase A; Activator (genetics); Adenylate kinase; Biology; DNA synthesis; Incubation; Phosphorylation; Protein kinase C; Toxin; Molecular biology; Endocrinology; Internal medicine; Biochemistry; Enzyme; Receptor; In vitro; Medicine","score_opus":0.004369762327301049,"score_gpt":0.22583029170138388,"score_spread":0.22146052937408284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4243989774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99712205,0.0023867658,0.000038110553,0.00007048944,0.00011350589,0.00022821467,0.000014491824,5.648022e-7,0.000025834905],"genre_scores_gemma":[0.99937624,0.0001605186,0.00010992187,0.0002053725,0.00011648267,0.000008971636,0.000003822397,0.000009069417,0.00000960884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905866,0.00024942646,0.00027008675,0.0001682612,0.000039596252,0.00021397955],"domain_scores_gemma":[0.99944085,0.000024217383,0.00014686721,0.000071784685,0.000085868596,0.00023043467],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032568074,0.0001221935,0.00034339816,0.00014204808,0.00004023983,0.0000034137004,0.00010351681,0.00014981677,0.00019209947],"category_scores_gemma":[0.000025775777,0.000107071326,0.000062251376,0.00008672887,0.00012076452,0.0000069118323,0.000022476997,0.0001490669,2.9226752e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029460376,0.000022835286,0.00085981755,0.000047219233,0.000062015286,0.00002731122,0.00043697984,0.00023976272,0.9963243,0.000015909975,0.000055405413,0.0016138501],"study_design_scores_gemma":[0.0013782129,0.0025951068,0.0044067474,0.0000315083,0.00002816268,0.000012758227,0.00007301148,0.00002403663,0.9870551,0.00008349021,0.0042165667,0.00009526546],"about_ca_topic_score_codex":0.00040278706,"about_ca_topic_score_gemma":0.0004097575,"teacher_disagreement_score":0.0092691565,"about_ca_system_score_codex":0.000010462211,"about_ca_system_score_gemma":0.00017016324,"threshold_uncertainty_score":0.4366242},"labels":[],"label_agreement":null},{"id":"W4244042259","doi":"10.1007/978-3-540-68706-1_1384","title":"Sympathetic Neurons","year":2010,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Neuroscience; Psychology","score_opus":0.008912759355350445,"score_gpt":0.2076078221799269,"score_spread":0.19869506282457647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244042259","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009715472,0.00047675532,0.001901753,0.00006281134,0.00068856595,0.00015947346,0.00002153213,0.000027288448,0.9956903],"genre_scores_gemma":[0.010546738,0.00032852736,0.0011819754,0.00038520704,0.00063472474,0.0000052877044,0.00015453939,0.00008893859,0.9866741],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992079,0.0000050532335,0.0001558431,0.00036345384,0.0001094132,0.00015832623],"domain_scores_gemma":[0.9993746,0.000003799739,0.00006957042,0.00041978477,0.000047255246,0.00008495323],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000618009,0.00023183477,0.0001596203,0.0000332092,0.000054999542,0.00002191769,0.00018492692,0.0005906148,0.003825325],"category_scores_gemma":[0.000008057071,0.00020598507,0.0001844792,0.000004228242,0.000045297027,5.142138e-7,0.00010016072,0.0002671118,0.00020951552],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000038023877,0.000007074299,7.356176e-7,0.000007904892,0.000035238652,0.0000058152195,0.000004749281,0.0000013550572,0.9436288,0.050590236,0.0018203065,0.0038940038],"study_design_scores_gemma":[0.000069084956,0.00012074504,3.0396328e-7,0.000010175129,0.00002004654,0.000015840911,0.0000013194353,0.0000026764928,0.2235268,0.004216894,0.77179,0.00022606771],"about_ca_topic_score_codex":0.0000023113084,"about_ca_topic_score_gemma":0.000012684567,"teacher_disagreement_score":0.7699697,"about_ca_system_score_codex":0.0000034999093,"about_ca_system_score_gemma":0.00004869173,"threshold_uncertainty_score":0.99708533},"labels":[],"label_agreement":null},{"id":"W4244125511","doi":"10.1016/s1351-4180(09)70225-9","title":"Alfa Laval wins Novozymes order for ethanol plant equipment","year":2009,"lang":"en","type":"article","venue":"Focus on Catalysts","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Residence time (fluid dynamics); Residence; Interpretation (philosophy); Order (exchange); Ligand (biochemistry); Kinetics; Mathematics; Chemistry; Computer science; Biochemical engineering; Engineering; Receptor; Physics; Biochemistry; Economics; Demography; Sociology","score_opus":0.013187527498376274,"score_gpt":0.255686783440946,"score_spread":0.2424992559425697,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244125511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97129804,0.0017659246,0.014019514,0.0034847243,0.0010609548,0.0013419968,0.0004674537,0.00008902589,0.0064723887],"genre_scores_gemma":[0.995872,0.000060777773,0.0012629064,0.0006311995,0.00037889724,0.000037435977,0.0005586113,0.000021595723,0.0011765605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900854,0.000017331588,0.00017688138,0.000356522,0.0001468253,0.00029393286],"domain_scores_gemma":[0.99949634,0.000011013563,0.00006307764,0.00028095703,0.00006139832,0.000087214874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014437705,0.00017158824,0.00015859639,0.000040480718,0.00008569251,0.000026611204,0.00017530471,0.00020048133,0.000028864055],"category_scores_gemma":[0.000036452933,0.00014750358,0.00011274259,0.000057249337,0.00001439785,0.0000029767327,0.000031760166,0.00008440386,0.000022006903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016810474,0.00010018441,0.000012225058,0.0000075030935,0.00004616278,0.000004382419,0.00006750194,0.000043546777,0.9748291,0.00061092275,0.0076894998,0.01642086],"study_design_scores_gemma":[0.00060724904,0.0009652289,0.000036404323,0.0000184203,0.000017247077,0.000008644771,0.000026860023,0.000044505603,0.95159394,0.0005585037,0.045918036,0.00020498359],"about_ca_topic_score_codex":0.000013472595,"about_ca_topic_score_gemma":0.000019120189,"teacher_disagreement_score":0.038228538,"about_ca_system_score_codex":0.00001606776,"about_ca_system_score_gemma":0.000058586334,"threshold_uncertainty_score":0.6015021},"labels":[],"label_agreement":null},{"id":"W4244914899","doi":"10.1096/fj.10.164061","title":"Combining resonance energy transfer methods reveals a complex between the α <sub>2A</sub> ‐adrenergic receptor, Gα <sub>i1</sub> β <sub>1</sub> γ <sub>2</sub> , and GRK2","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Beta adrenergic receptor kinase; G protein-coupled receptor kinase; G protein-coupled receptor; Receptor; Förster resonance energy transfer; Kinase; Chemistry; Cell biology; Biophysics; 5-HT5A receptor; Biology; Biochemistry; Physics; Fluorescence","score_opus":0.01891333937756693,"score_gpt":0.2595871430472266,"score_spread":0.24067380366965965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244914899","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9699643,0.0036375076,0.023339527,0.0008670587,0.0012909005,0.0004748866,0.00014876225,0.0000738781,0.00020313592],"genre_scores_gemma":[0.98713285,0.006507352,0.0019090966,0.0012100064,0.002681264,0.000081986545,0.00020928566,0.00023585073,0.000032329874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9926398,0.001987407,0.0015522272,0.0012362624,0.0009430403,0.0016412718],"domain_scores_gemma":[0.9962652,0.0005442621,0.00067923643,0.0012889316,0.00046135185,0.000761038],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.004862984,0.0010985233,0.0011763531,0.00024137276,0.0018900742,0.00050601584,0.0014830987,0.0009000182,0.000058196136],"category_scores_gemma":[0.00031222554,0.0008024695,0.0007788071,0.00057029654,0.0007128694,0.0000795824,0.00044172493,0.002134457,0.000026020494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029622414,0.00009238483,0.00020343265,0.00003165031,0.00033653495,0.000025072195,0.0003779062,0.00011818257,0.8834123,0.000582174,0.0014537518,0.113070354],"study_design_scores_gemma":[0.0019891958,0.0006857872,0.0007658496,0.00018976598,0.0003229168,0.0005497777,0.00027943455,0.00033051445,0.9867273,0.0021893294,0.004941011,0.0010291289],"about_ca_topic_score_codex":0.000028219592,"about_ca_topic_score_gemma":0.00010560839,"teacher_disagreement_score":0.11204123,"about_ca_system_score_codex":0.0000846389,"about_ca_system_score_gemma":0.00032291652,"threshold_uncertainty_score":0.99944264},"labels":[],"label_agreement":null},{"id":"W4245587174","doi":"10.1007/978-3-319-67199-4_101763","title":"DREAM (Downstream Regulatory Element Antagonist Modulator)","year":2017,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Downstream (manufacturing); Antagonist; Chemistry; Engineering; Receptor; Operations management","score_opus":0.012402085451445126,"score_gpt":0.2348991100045564,"score_spread":0.22249702455311127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4245587174","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0024312525,0.0015351888,0.0011463432,0.0000670896,0.00088049035,0.00041971082,0.00011065591,0.000048554713,0.9933607],"genre_scores_gemma":[0.07331584,0.00082900265,0.00086857344,0.0002087345,0.001261133,0.000014093284,0.0007774825,0.00013152443,0.9225936],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99819165,0.000010688228,0.0003774471,0.00077135174,0.0003108199,0.00033802248],"domain_scores_gemma":[0.9979848,0.0000035894168,0.0003321311,0.0013894563,0.00011579327,0.00017418596],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001929279,0.00049884163,0.0003982843,0.000059527025,0.00027842078,0.00010492289,0.00048608283,0.00072352856,0.002329965],"category_scores_gemma":[0.000011120322,0.00046342128,0.00035369647,0.000003489475,0.00012904913,0.0000033841582,0.00026798216,0.00020535153,0.00013666178],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012920797,0.00008833137,0.00006231904,0.0001006726,0.00094131596,0.000051849445,0.000024718287,0.00004154657,0.71605015,0.15864058,0.07862196,0.04524737],"study_design_scores_gemma":[0.0003218813,0.00022854497,0.000012581058,0.0000666263,0.000060413753,0.000017714947,0.000006525143,0.000016114098,0.2247258,0.0031825486,0.7707524,0.0006088696],"about_ca_topic_score_codex":0.000020886137,"about_ca_topic_score_gemma":0.000036185964,"teacher_disagreement_score":0.69213045,"about_ca_system_score_codex":0.00004064677,"about_ca_system_score_gemma":0.00015832597,"threshold_uncertainty_score":0.9997817},"labels":[],"label_agreement":null},{"id":"W4246224178","doi":"10.25237/revchilanestv45s01.23","title":"Ketamine Increases the Function of γ-Aminobutyric Acid Type A Receptors in Hippocampal and Cortical Neurons","year":2016,"lang":"en","type":"article","venue":"Revista Chilena de Anestesia","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Hospital; University of Toronto","funders":"","keywords":"Hippocampal formation; Aminobutyric acid; Neuroscience; Receptor; Ketamine; Cortical neurons; Psychology; Internal medicine; Medicine","score_opus":0.00798933167540331,"score_gpt":0.21612680566858974,"score_spread":0.20813747399318644,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4246224178","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969066,0.0021670708,0.0006054144,0.00010049082,0.00004332865,0.00012627985,0.000004092474,0.000006101674,0.000040640592],"genre_scores_gemma":[0.99875027,0.0008297359,0.000086425454,0.00010368154,0.000105108265,0.000007616837,0.000014239686,0.0000143464595,0.00008860562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991806,0.00015235186,0.00020283645,0.00021032368,0.00008208599,0.00017181614],"domain_scores_gemma":[0.99955994,0.00005836125,0.000071954666,0.00020872241,0.000041351414,0.000059685703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002635723,0.00011239047,0.00014858015,0.000032919506,0.00004239609,0.000015888847,0.0000951369,0.00008339648,0.00006529173],"category_scores_gemma":[0.00024295275,0.000066281915,0.000045175813,0.00010566753,0.000077941004,0.0000048957454,0.00004505815,0.0000649818,0.0000033104268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012390161,0.000040372124,0.037609402,0.000027674903,0.000014489662,0.0000028790687,0.000017469816,0.0000014772958,0.95556736,0.000552133,0.00015258724,0.005890273],"study_design_scores_gemma":[0.002286742,0.0027130935,0.4163337,0.00047326938,0.00019296166,0.00030451835,0.0002108742,0.0001367678,0.5453521,0.00034530467,0.030952284,0.000698386],"about_ca_topic_score_codex":0.000013020655,"about_ca_topic_score_gemma":0.0000046837113,"teacher_disagreement_score":0.41021526,"about_ca_system_score_codex":0.000009757256,"about_ca_system_score_gemma":0.000046556845,"threshold_uncertainty_score":0.2702898},"labels":[],"label_agreement":null},{"id":"W4246711226","doi":"10.7287/peerj.preprints.4043","title":"Phylogenetic evidence suggests a later origin of the DRD<sub>2l</sub> and DRD<sub>4rs</sub> dopamine receptor gene lineages","year":2018,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Biology; Dopamine receptor; Dopamine; Phylogenetic tree; Monophyly; Sister group; Dopaminergic; Receptor; Clade; Genetics; Gene; Neuroscience","score_opus":0.018527421291605593,"score_gpt":0.2544743498674507,"score_spread":0.23594692857584512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4246711226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891926,0.0066797966,0.0015600328,0.00021620138,0.0012509199,0.0008607599,0.00010688238,0.000035639012,0.00009718858],"genre_scores_gemma":[0.98291886,0.012381538,0.0024118589,0.00025780645,0.0012907936,0.00008162424,0.00016146869,0.00011219024,0.00038383406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996344,0.0002964505,0.00084478233,0.0014163976,0.0004766677,0.0006217078],"domain_scores_gemma":[0.997228,0.0000752912,0.0005667182,0.001453916,0.0004544583,0.00022158482],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00063471805,0.00075307436,0.0007236589,0.00011309721,0.0001740644,0.00012222744,0.0009104982,0.0009768866,0.00015776457],"category_scores_gemma":[0.0002422324,0.0005552982,0.00040207995,0.00016856959,0.00037175394,0.000009516053,0.0018228112,0.00049355277,0.00002979567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000104043764,0.000070303926,0.0019735098,0.000243419,0.00019040458,0.0000031171398,0.00006705938,0.00012211659,0.99215275,0.000013309453,0.0014539751,0.003605972],"study_design_scores_gemma":[0.00042106237,0.00040660787,0.0012529686,0.00047598322,0.00014064062,0.000024431884,0.000024065936,0.00018060558,0.99443096,0.00018667667,0.0017859853,0.00067000085],"about_ca_topic_score_codex":0.00005133394,"about_ca_topic_score_gemma":0.00008717177,"teacher_disagreement_score":0.006273694,"about_ca_system_score_codex":0.000042673564,"about_ca_system_score_gemma":0.00029205155,"threshold_uncertainty_score":0.9996899},"labels":[],"label_agreement":null},{"id":"W4247216252","doi":"10.3410/f.717952823.793458291","title":"Faculty Opinions recommendation of Multiple inhibitory G-protein-coupled receptors resist acute desensitization in the presynaptic but not postsynaptic compartments of neurons.","year":2012,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Inhibitory postsynaptic potential; Postsynaptic potential; Desensitization (medicine); Neuroscience; Receptor; Chemistry; Cell biology; Biophysics; Biology; Biochemistry","score_opus":0.025667958974746895,"score_gpt":0.31284106034909165,"score_spread":0.28717310137434476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4247216252","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0007011236,0.00067902927,0.00008901543,0.016525622,0.0006995677,0.0018488726,0.9794401,0.000009208714,0.00000748265],"genre_scores_gemma":[0.005277404,0.00027731003,0.00055558333,0.0011741968,0.00022469663,0.00019733194,0.99209315,0.000028013617,0.00017230766],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99583113,0.0008620058,0.0014756368,0.00053553033,0.00096000015,0.00033572287],"domain_scores_gemma":[0.9948548,0.000104332554,0.0015023754,0.0011535658,0.0022432702,0.00014166551],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015591946,0.00043107735,0.0007132284,0.00022361126,0.00015678706,0.00005222212,0.0011112259,0.0006317301,0.00013088243],"category_scores_gemma":[0.0033184802,0.00027643927,0.00043710088,0.0008424979,0.0002736248,0.000041875843,0.00036022434,0.000586729,0.0000096511485],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006792116,0.00040165518,0.0000122067795,0.0020561412,0.00017796675,2.131039e-7,0.00008826216,0.0000012534821,0.0066279946,0.00004988494,0.9901736,0.00034292825],"study_design_scores_gemma":[0.0007400109,0.00028913302,0.00069719786,0.003117721,0.0001935103,0.000018226672,0.00005502804,0.000049415645,0.005914219,0.0000060296725,0.9886507,0.00026881797],"about_ca_topic_score_codex":0.00007589047,"about_ca_topic_score_gemma":0.000014971938,"teacher_disagreement_score":0.015351426,"about_ca_system_score_codex":0.000053198288,"about_ca_system_score_gemma":0.0002662786,"threshold_uncertainty_score":0.99996877},"labels":[],"label_agreement":null},{"id":"W4248397541","doi":"10.3410/f.1026395.325073","title":"Faculty Opinions recommendation of G protein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels.","year":2005,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Inhibitory postsynaptic potential; Chemistry; Biophysics; Biology; Neuroscience","score_opus":0.022238967631559,"score_gpt":0.31848800555343443,"score_spread":0.2962490379218754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4248397541","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000022324615,0.002283499,0.00007658598,0.021399409,0.0010039401,0.0013635672,0.97380406,0.00001322305,0.000033378295],"genre_scores_gemma":[0.00015540299,0.00047364304,0.0009696692,0.0009990853,0.00062046666,0.00010532773,0.995586,0.000033134194,0.0010573028],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9962892,0.00036250488,0.0014759334,0.00064198,0.00091748545,0.00031287514],"domain_scores_gemma":[0.99168515,0.00002331491,0.0015550817,0.0012048561,0.005324232,0.00020736063],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010376509,0.0004733214,0.0008080041,0.00022693022,0.00013561198,0.00004828559,0.0011279158,0.0009536956,0.0005343828],"category_scores_gemma":[0.0026811725,0.00033144865,0.00055345346,0.001028356,0.00024210017,0.00003378887,0.00044735163,0.00059974723,0.000017527047],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028973413,0.00030707134,6.799775e-7,0.0036646053,0.00015112534,9.23951e-8,0.000032239743,0.0000017353707,0.0016750077,0.00007918211,0.99292046,0.0011388081],"study_design_scores_gemma":[0.00051208335,0.0003247583,0.000022362796,0.0055863773,0.00009404179,0.000011069411,0.000016456075,0.000017514058,0.011079965,0.000013196714,0.9820134,0.00030878198],"about_ca_topic_score_codex":0.000051119925,"about_ca_topic_score_gemma":0.0000044150415,"teacher_disagreement_score":0.021781893,"about_ca_system_score_codex":0.000048787813,"about_ca_system_score_gemma":0.0005144279,"threshold_uncertainty_score":0.99991375},"labels":[],"label_agreement":null},{"id":"W4248857075","doi":"10.21203/rs.3.rs-54406/v1","title":"Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Montréal; McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University Health Centre; Réseau Québécois de Recherche sur les Médicaments; McGill University","keywords":"Endocytosis; Dual (grammatical number); G protein-coupled receptor; Drug discovery; Chemistry; Cell biology; Receptor; Biology; Art; Biochemistry; Literature","score_opus":0.05338083311433072,"score_gpt":0.3449016509157354,"score_spread":0.29152081780140465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4248857075","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99135816,0.004270105,0.00186205,0.0002736431,0.00012696853,0.0005537892,0.0012482685,0.000011507676,0.0002955244],"genre_scores_gemma":[0.9954252,0.0012567407,0.0010077136,0.00003239219,0.00096761086,0.0000693543,0.0010475361,0.000046110817,0.00014731198],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99757874,0.00032109057,0.00031844157,0.0008024618,0.0006059004,0.0003733513],"domain_scores_gemma":[0.99888545,0.00008675341,0.000111957575,0.0005171994,0.00023047699,0.00016815429],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004613581,0.00024121196,0.0003915524,0.00010725696,0.000087683045,0.00013820305,0.0002910748,0.00042385992,0.000071768336],"category_scores_gemma":[0.00035716922,0.00022397688,0.0001934322,0.00010869649,0.00015838345,0.0000058487917,0.0016523551,0.000659544,0.0000062099953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002752867,0.000052828018,0.00087461266,0.00028683775,0.00016615463,0.000019329445,0.00021032484,0.000014765133,0.9955576,0.00014531889,0.0012372605,0.0011596712],"study_design_scores_gemma":[0.000559929,0.00047892972,0.000808072,0.0004343877,0.000025265343,0.0000022102313,0.0004622362,0.00011253915,0.9932143,0.0013372349,0.002296828,0.00026806875],"about_ca_topic_score_codex":0.0010282805,"about_ca_topic_score_gemma":0.00006581939,"teacher_disagreement_score":0.004067086,"about_ca_system_score_codex":0.00002572163,"about_ca_system_score_gemma":0.00031723254,"threshold_uncertainty_score":0.91335124},"labels":[],"label_agreement":null},{"id":"W4249429715","doi":"10.3410/f.737362601.793581984","title":"Faculty Opinions recommendation of Morphine-induced respiratory depression is independent of β-arrestin2 signalling.","year":2021,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Morphine; Signalling; Depression (economics); Psychology; Pharmacology; Medicine; Biology; Economics; Cell biology","score_opus":0.037066836410620536,"score_gpt":0.3443956556637286,"score_spread":0.30732881925310807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249429715","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000051275914,0.0031053186,0.00017616471,0.012165521,0.000822628,0.0007950914,0.9828506,0.000009966603,0.000023448416],"genre_scores_gemma":[0.00021876516,0.00042941468,0.0006561503,0.0024415397,0.00036055807,0.00010381578,0.99551606,0.0000315051,0.00024218974],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9955541,0.00047701952,0.0016499341,0.0007715488,0.001262401,0.00028500962],"domain_scores_gemma":[0.9911403,0.000055330212,0.0019143843,0.0013554872,0.0053087086,0.00022576484],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013189908,0.0004715111,0.0008508963,0.00021396593,0.00014908917,0.000057180612,0.0012560285,0.0010355002,0.00055608316],"category_scores_gemma":[0.0037076592,0.00032973048,0.0007015324,0.000913033,0.00014269064,0.00002906781,0.00066296017,0.00073067355,0.0000065904983],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022647802,0.0002786501,0.0000093716535,0.0034638355,0.0001655288,3.2143927e-7,0.00003961896,6.5179273e-7,0.008199542,0.00001578042,0.98645186,0.001352183],"study_design_scores_gemma":[0.0005478983,0.00019577215,0.00021164822,0.0074211997,0.00013471078,0.000013816725,0.000028221855,0.000006169183,0.033555552,0.000010330554,0.9575787,0.0002959649],"about_ca_topic_score_codex":0.00004339155,"about_ca_topic_score_gemma":0.0000045993406,"teacher_disagreement_score":0.028873153,"about_ca_system_score_codex":0.000040876264,"about_ca_system_score_gemma":0.00069184275,"threshold_uncertainty_score":0.9999155},"labels":[],"label_agreement":null},{"id":"W4249989858","doi":"10.1007/978-1-4614-6438-9_101763-1","title":"DREAM (Downstream Regulatory Element Antagonist Modulator)","year":2016,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Downstream (manufacturing); Dream; Antagonist; Chemistry; Engineering; Psychology; Neuroscience; Operations management; Receptor","score_opus":0.008643076896907671,"score_gpt":0.21467656131481638,"score_spread":0.20603348441790872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4249989858","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022693544,0.0014013386,0.003715569,0.00010772645,0.00077119214,0.0004189109,0.00015443587,0.000063168765,0.9910983],"genre_scores_gemma":[0.051920865,0.00079960725,0.0007496695,0.0003180807,0.0013712075,0.000015884152,0.00035811143,0.00014262524,0.94432396],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99814063,0.000013280291,0.00041846084,0.0007618823,0.00030959767,0.00035614488],"domain_scores_gemma":[0.99866396,0.000005957501,0.00021002743,0.0008311409,0.000112939255,0.00017599967],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016819383,0.00049040676,0.0003581566,0.00006959257,0.000115091374,0.00003950018,0.00029787424,0.0006726589,0.0044888332],"category_scores_gemma":[0.000006676622,0.00038295757,0.00033022085,0.000008855522,0.00009953626,0.0000026772834,0.00019920073,0.0001400325,0.00023042323],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006562281,0.000034031607,0.000019765917,0.000033698772,0.00038310597,0.0000135725195,0.000007241792,0.000005918559,0.73927605,0.20555098,0.02744101,0.02716902],"study_design_scores_gemma":[0.0003492312,0.0002291464,0.00000450834,0.000077463184,0.00004182544,0.000014602517,0.0000052684604,0.0000042498846,0.31452954,0.004675314,0.6795088,0.0005600415],"about_ca_topic_score_codex":0.000004429897,"about_ca_topic_score_gemma":0.000010692439,"teacher_disagreement_score":0.6520678,"about_ca_system_score_codex":0.000053565414,"about_ca_system_score_gemma":0.00013610157,"threshold_uncertainty_score":0.99986225},"labels":[],"label_agreement":null},{"id":"W4250295959","doi":"10.3410/f.1070817.523752","title":"Faculty Opinions recommendation of D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum.","year":2007,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Dopamine receptor D2; Agonist; Dopamine receptor D1; Dopamine; Dopamine receptor; Receptor; Chemistry; G protein-coupled receptor; Partial agonist; Pharmacology; Dopamine receptor D3; D1-like receptor; Neuroscience; Biology; Biochemistry","score_opus":0.02426472697804012,"score_gpt":0.34008559808608413,"score_spread":0.315820871108044,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4250295959","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019475778,0.00035866137,0.000443187,0.04856311,0.0005068176,0.0018077876,0.9481072,0.0000075898056,0.000010909513],"genre_scores_gemma":[0.00051058724,0.00043961647,0.00090333837,0.003712693,0.00028676336,0.00022115922,0.9938148,0.00002413765,0.00008687623],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964486,0.00058328704,0.0012701354,0.0005625382,0.0008272141,0.0003082558],"domain_scores_gemma":[0.9944958,0.00010348703,0.0015754148,0.00084518397,0.0028263368,0.00015379241],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001950637,0.000413694,0.00073689426,0.00033658821,0.000102672326,0.000038288457,0.0011624539,0.00064184633,0.000254041],"category_scores_gemma":[0.0014842154,0.00024412427,0.00031481797,0.0012979669,0.000179017,0.00003122851,0.00022589024,0.0005934233,0.000003405588],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010436318,0.00032374405,0.000010109802,0.0017377135,0.00012858251,1.4609556e-7,0.00007130653,0.0000025354918,0.0031785697,0.000036778638,0.9935469,0.0008592727],"study_design_scores_gemma":[0.00091623206,0.00048280382,0.00024731556,0.0032856131,0.000091631,0.000010203462,0.00013076705,0.0000069970974,0.010890482,0.0000023964124,0.983687,0.0002485469],"about_ca_topic_score_codex":0.00008068917,"about_ca_topic_score_gemma":0.000022886363,"teacher_disagreement_score":0.04570765,"about_ca_system_score_codex":0.00006528559,"about_ca_system_score_gemma":0.0003190351,"threshold_uncertainty_score":0.99550986},"labels":[],"label_agreement":null},{"id":"W4250302984","doi":"10.1016/s0960-894x(02)00607-8","title":"Novel substituted 4-aminomethylpiperidines as potent and selective human β3-agonists. Part 1: aryloxypropanolaminomethylpiperidines","year":2002,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Chemistry; Pharmacophore; Chemical synthesis; In vitro; In vivo; Structure–activity relationship; Agonist; Chinese hamster ovary cell; Stereochemistry; Combinatorial chemistry; Pharmacology; Biochemistry; Receptor","score_opus":0.017580968270466076,"score_gpt":0.22118722647441347,"score_spread":0.2036062582039474,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4250302984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99385476,0.0026212665,0.0007592546,0.0016377004,0.00027110524,0.0002205731,0.00002122101,0.000058796486,0.0005553042],"genre_scores_gemma":[0.99617213,0.00038690647,0.00037426502,0.00083478604,0.0013704952,0.00003919135,0.00017244593,0.000065626184,0.00058416865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977474,0.000033263826,0.00042788486,0.0008744157,0.00035676887,0.0005602273],"domain_scores_gemma":[0.9989559,0.00001907964,0.00018535108,0.000430535,0.00010553566,0.00030358133],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022367653,0.00047495042,0.00040032418,0.0000586862,0.00031665174,0.000066942484,0.00033227532,0.00025732454,0.0006654463],"category_scores_gemma":[0.00016047193,0.00044153203,0.00013301811,0.00024848784,0.00032675578,0.000014259017,0.00013841267,0.00027414048,0.00001874489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034743236,0.000103610735,0.0003225113,0.000075618846,0.0001195509,0.000026731439,0.00012638282,0.0000024289109,0.99691015,0.000014616342,0.00154546,0.00071821635],"study_design_scores_gemma":[0.0010244314,0.00012889739,0.0005994732,0.000051489184,0.00008100496,0.0003698718,0.0002174888,0.000031800213,0.9892264,0.000010645638,0.007726921,0.00053158804],"about_ca_topic_score_codex":0.00004750336,"about_ca_topic_score_gemma":0.0000025492152,"teacher_disagreement_score":0.0076837405,"about_ca_system_score_codex":0.00006170212,"about_ca_system_score_gemma":0.000043289707,"threshold_uncertainty_score":0.99980366},"labels":[],"label_agreement":null},{"id":"W4250651104","doi":"10.1139/y00-015","title":"Vascular β-adrenoceptor function in hypertension and in ageing","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Intracellular; Cell biology; Adenylyl cyclase; Biology; Agonist; Signal transduction; Receptor; G protein-coupled receptor; Protein kinase A; Vascular smooth muscle; Endocrinology; Second messenger system; G protein; Internal medicine; Phosphorylation; Biochemistry; Medicine","score_opus":0.00787113573298698,"score_gpt":0.21579089208856206,"score_spread":0.20791975635557508,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4250651104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960502,0.0034844978,0.000012896278,0.00010210163,0.00026146253,0.00004834983,0.0000013681155,6.061503e-7,0.000038556052],"genre_scores_gemma":[0.99803936,0.0010237404,0.000045625595,0.00065726595,0.00019396564,0.0000017470965,0.000004188369,0.0000064797055,0.000027603046],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936306,0.00011323596,0.00017834365,0.00013686957,0.000021298249,0.00018719315],"domain_scores_gemma":[0.9997399,0.000010390599,0.000044324228,0.00003677509,0.000026561353,0.00014203919],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00019519383,0.00007940086,0.0001639723,0.00012329638,0.00004736178,0.000004330618,0.00005127348,0.00013925642,0.0016072314],"category_scores_gemma":[0.000008342094,0.00007468573,0.000029553707,0.00005430509,0.00007115451,0.000007047176,0.000007156007,0.00016359948,0.0000013488796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012831618,0.00000953347,0.0012987154,0.000010583033,0.000022212336,0.00004542872,0.000053291285,0.00023380102,0.99413574,0.0000074232257,0.00018806082,0.003866912],"study_design_scores_gemma":[0.0044959495,0.001125858,0.08630133,0.0000645232,0.00007319176,0.0003484254,0.00017067605,0.00037819744,0.86623645,0.0013750016,0.039059166,0.00037125897],"about_ca_topic_score_codex":0.0003813292,"about_ca_topic_score_gemma":0.0015393167,"teacher_disagreement_score":0.1278993,"about_ca_system_score_codex":0.000011808273,"about_ca_system_score_gemma":0.00011324128,"threshold_uncertainty_score":0.9993054},"labels":[],"label_agreement":null},{"id":"W4250743277","doi":"10.1139/y99-137","title":"Distribution of α<sub>1</sub>-adrenoceptor subtype proteins in different tissues of neonatal and adult rats","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"McGill University; Heart and Stroke Foundation of Canada","keywords":"Vas deferens; Endocrinology; Internal medicine; Kidney; Biology; Receptor; Adrenergic receptor; Prostate; Medicine","score_opus":0.0054461302702441565,"score_gpt":0.22394238197090585,"score_spread":0.2184962517006617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4250743277","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978408,0.0017235944,0.000039864437,0.0000930855,0.0001385955,0.00009626514,0.0000591418,5.4952017e-7,0.000008101139],"genre_scores_gemma":[0.99881124,0.0008744974,0.00003172995,0.00006505025,0.0001518153,0.0000029251166,0.0000466619,0.000006071925,0.000010002916],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928594,0.000108088796,0.00027346317,0.00012526884,0.000034084947,0.00017314061],"domain_scores_gemma":[0.9995389,0.000015367534,0.00014804215,0.00004784911,0.000098016535,0.00015184144],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009690094,0.000102464204,0.00026006968,0.000060659815,0.00003653785,0.000002236333,0.00008016272,0.00014516177,0.0005432345],"category_scores_gemma":[0.000014542267,0.000088140136,0.000044032477,0.000044427725,0.00019147538,0.0000060980897,0.000011220567,0.00012751258,3.9835416e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024209451,0.000021257887,0.0011094759,0.00004538144,0.00005020159,0.0000078562025,0.00011030955,0.00003374719,0.9920034,0.000041833533,0.0002683658,0.0060660853],"study_design_scores_gemma":[0.00066605257,0.0007019639,0.0072311745,0.000019228753,0.000024629237,0.00003380012,0.000038412814,0.000020914204,0.9899993,0.00028978538,0.0008976052,0.00007712168],"about_ca_topic_score_codex":0.00019002412,"about_ca_topic_score_gemma":0.00063900044,"teacher_disagreement_score":0.0061216988,"about_ca_system_score_codex":0.000009798694,"about_ca_system_score_gemma":0.0001473588,"threshold_uncertainty_score":0.5948037},"labels":[],"label_agreement":null},{"id":"W4250866230","doi":"10.1016/j.bpj.2014.11.1990","title":"Specific Protein-Lipid Interactions Stabilize an Active State of the Beta 2 Adrenergic Receptor","year":2015,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"G protein-coupled receptor; Intracellular; Receptor; Biophysics; Extracellular; Chemistry; Adrenergic receptor; Cell biology; Biology; Biochemistry","score_opus":0.0241171724902006,"score_gpt":0.26098191699583034,"score_spread":0.23686474450562975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4250866230","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99732757,0.00003330156,0.0014832006,0.00012551007,0.0006405718,0.00013112923,0.000026613885,0.0000047632534,0.00022735538],"genre_scores_gemma":[0.99767447,0.000024674084,0.0008473356,0.00002903792,0.0010686396,0.000006989548,0.000013451488,0.000018580817,0.00031682188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898666,0.00016506448,0.00023505925,0.00019105122,0.00023793698,0.00018422051],"domain_scores_gemma":[0.99910957,0.0000065413633,0.00019950076,0.00025697474,0.00023510076,0.00019229153],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016006612,0.00012782874,0.0001464037,0.00002427909,0.00010193246,0.000041060724,0.00027784964,0.000048067956,0.000097641394],"category_scores_gemma":[0.00002860255,0.000084294355,0.00016539254,0.000097573684,0.00008496144,0.000016056736,0.00008610709,0.00022510665,0.000009467951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001867733,0.00015671445,0.00001292501,0.0000022210545,0.000036003654,6.587459e-7,0.00012801179,0.00012272927,0.9943763,0.00010814666,0.00042933776,0.0044401893],"study_design_scores_gemma":[0.00034984993,0.00046643114,0.00009805312,0.000019612384,0.000008869251,0.000016362565,0.00020414442,0.000044132063,0.98414266,0.00024830143,0.0142893065,0.00011227034],"about_ca_topic_score_codex":0.0000054178277,"about_ca_topic_score_gemma":0.0000035650128,"teacher_disagreement_score":0.013859969,"about_ca_system_score_codex":0.00003272622,"about_ca_system_score_gemma":0.00011791257,"threshold_uncertainty_score":0.3437424},"labels":[],"label_agreement":null},{"id":"W4251716948","doi":"10.1111/j.1768-322x.2004.tb01430.x","title":"Delineation of the conserved functional properties of D<sub>1A</sub>, D<sub>1B</sub> and D<sub>1C</sub> dopamine receptor subtypes in vertebrates","year":2004,"lang":"en","type":"article","venue":"Biology of the Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"National Institutes of Health; Institut Universitaire de France; Fondation pour la Recherche Médicale","keywords":"Biology; Receptor; Desensitization (medicine); Agonist; Vertebrate; Xenopus; Dopamine; Dopamine receptor; Amphibian; Neuroscience; Gene; Cell biology; Genetics; Ecology","score_opus":0.011641245543601601,"score_gpt":0.18562634088226931,"score_spread":0.1739850953386677,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4251716948","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99578625,0.0028471933,0.00032632542,0.00023848817,0.00039816738,0.00032910175,0.00004219882,0.000006600201,0.000025699026],"genre_scores_gemma":[0.9987503,0.0008288718,0.00010029127,0.000104248444,0.00009304503,0.000018939194,0.00006167672,0.000020545976,0.000022068109],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99858284,0.00020507033,0.0005137601,0.00033600698,0.00012923381,0.00023306435],"domain_scores_gemma":[0.99900275,0.000032496704,0.0003730911,0.00034125795,0.00020970593,0.000040679075],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036027847,0.00022041162,0.00032438553,0.000062171974,0.0000895288,0.0000066402995,0.00027324818,0.0003105142,0.000007974915],"category_scores_gemma":[0.00013820294,0.00014187346,0.00016222728,0.00015545318,0.00044196233,0.00000944705,0.00019206524,0.0001416813,0.0000028975514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032381792,0.00013386505,0.0036634018,0.00008551389,0.00005108019,1.5474815e-7,0.000066205655,0.00032581724,0.9944577,0.00008652874,0.00010085712,0.0007050159],"study_design_scores_gemma":[0.0011281818,0.00033661316,0.0020727126,0.0000958168,0.000036422953,0.0000053942395,0.00010724354,0.00008931622,0.9955924,0.00025549717,0.00011931682,0.00016104634],"about_ca_topic_score_codex":0.000058127916,"about_ca_topic_score_gemma":0.00013811138,"teacher_disagreement_score":0.0029640875,"about_ca_system_score_codex":0.000023610843,"about_ca_system_score_gemma":0.00016662347,"threshold_uncertainty_score":0.5785432},"labels":[],"label_agreement":null},{"id":"W4252146510","doi":"10.1007/978-3-319-67199-4_101765","title":"GRK2 (G Protein-Coupled Receptor Kinase 2)","year":2017,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Beta adrenergic receptor kinase; G protein-coupled receptor kinase; Chemistry; G protein-coupled receptor; Receptor; Biochemistry","score_opus":0.014813325317711137,"score_gpt":0.232550791834931,"score_spread":0.21773746651721987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4252146510","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002862864,0.0015809236,0.0023625577,0.0001229628,0.0008214583,0.0009488393,0.00007162096,0.00005669424,0.9911721],"genre_scores_gemma":[0.008025054,0.00034837794,0.0021377422,0.00014810174,0.0012506043,0.000040773943,0.0004929145,0.00012516776,0.9874313],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985201,0.000010632862,0.00028763362,0.0006706633,0.00022253799,0.0002884628],"domain_scores_gemma":[0.99843735,0.0000035488522,0.00028311735,0.0009859948,0.0001395935,0.00015042009],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018120083,0.00043101335,0.00035049865,0.000049677274,0.00019459131,0.000085985506,0.00046279668,0.00079234806,0.0069047483],"category_scores_gemma":[0.000043172622,0.00038490669,0.00030848768,0.0000035715548,0.000074951444,0.000002780255,0.000215351,0.00023368826,0.0004393551],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000602979,0.000013152056,6.3692147e-7,0.00003751621,0.00012153749,0.000010160159,0.000006421296,0.0000010102034,0.9657928,0.020239078,0.0093476325,0.004369755],"study_design_scores_gemma":[0.0002694097,0.00022795683,3.1399028e-7,0.00009740903,0.0000245286,0.000004472064,0.0000035187813,0.000009136581,0.3294558,0.0024384598,0.6669992,0.00046975276],"about_ca_topic_score_codex":0.000017641536,"about_ca_topic_score_gemma":0.000027799477,"teacher_disagreement_score":0.6576516,"about_ca_system_score_codex":0.000019598683,"about_ca_system_score_gemma":0.00012799517,"threshold_uncertainty_score":0.9998603},"labels":[],"label_agreement":null},{"id":"W4252500475","doi":"10.1002/ange.201302374","title":"Opsin, a Structural Model for Olfactory Receptors?","year":2013,"lang":"en","type":"article","venue":"Angewandte Chemie","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto","funders":"","keywords":"G protein-coupled receptor; Opsin; Chemistry; Receptor; Rhodopsin; Stereochemistry; Biology; Biochemistry","score_opus":0.025087558839323364,"score_gpt":0.2473575851939129,"score_spread":0.22227002635458953,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4252500475","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.984345,0.0005916713,0.013140518,0.00012720167,0.0003160218,0.0004005051,0.000029043236,0.000029109982,0.0010208831],"genre_scores_gemma":[0.98662543,0.000049368504,0.007308294,0.00040005686,0.00039809683,0.00012771215,0.00024271454,0.000036766756,0.004811539],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99915814,0.0000078567555,0.00015719615,0.00030607902,0.000089354115,0.00028135342],"domain_scores_gemma":[0.9994779,0.00000855316,0.000058917325,0.00023286282,0.0001187257,0.00010299714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000070765855,0.00016397289,0.00013652672,0.00001978892,0.00009135546,0.000041143725,0.00016139263,0.00016657502,0.0004169161],"category_scores_gemma":[0.000040915806,0.00014431102,0.00013063881,0.000033260116,0.000032433378,0.00000882808,0.00005410579,0.00006110047,0.00001606012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018293527,0.000007604616,0.0000625018,0.000015222459,0.000027107044,1.03870605e-7,0.00006520973,0.00008564842,0.9791536,0.000054598815,0.019666236,0.0008438795],"study_design_scores_gemma":[0.0003778558,0.00007071411,0.00001934342,0.0000068284007,0.000011084558,0.000002660738,0.00005303765,0.0019973174,0.9857482,0.0011075623,0.010393452,0.00021194378],"about_ca_topic_score_codex":0.000016258968,"about_ca_topic_score_gemma":0.000004886823,"teacher_disagreement_score":0.009272784,"about_ca_system_score_codex":0.000015691967,"about_ca_system_score_gemma":0.000042063835,"threshold_uncertainty_score":0.5884833},"labels":[],"label_agreement":null},{"id":"W4253423415","doi":"10.3410/f.726494277.793530301","title":"Faculty Opinions recommendation of Monitoring G protein-coupled receptor and β-arrestin trafficking in live cells using enhanced bystander BRET.","year":2017,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Bystander effect; Cell biology; Chemistry; Biology; Immunology","score_opus":0.03088269801021827,"score_gpt":0.34843021700475213,"score_spread":0.3175475189945339,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4253423415","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00040723223,0.0017282814,0.00028444015,0.0054623736,0.00087554357,0.0013895072,0.9898375,0.000009762863,0.000005332284],"genre_scores_gemma":[0.00079280377,0.0004908532,0.0020646239,0.00020683843,0.00039227997,0.00012613424,0.9957189,0.000029095974,0.00017847728],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9970104,0.00029070213,0.0010750477,0.0006751185,0.00063348905,0.00031523552],"domain_scores_gemma":[0.99554634,0.000036776022,0.0014084118,0.00090295426,0.0019345211,0.0001710076],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011464948,0.00042954448,0.0006967965,0.00017817844,0.00024049377,0.00013642816,0.00086099765,0.000741843,0.00010972586],"category_scores_gemma":[0.0025175468,0.00031723877,0.0002899392,0.00038883972,0.00018969619,0.000044613535,0.00038694043,0.0006112806,0.0000039590623],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034282177,0.00015889118,0.000004464159,0.003737537,0.000093082985,2.0235451e-7,0.00014056006,0.0000020154691,0.029405043,0.000010872155,0.9651586,0.0012544617],"study_design_scores_gemma":[0.00064912945,0.00013215856,0.0000952417,0.013682113,0.000065103,0.000008008255,0.00006592308,0.000037136757,0.018606476,0.000006911186,0.96631485,0.00033695129],"about_ca_topic_score_codex":0.00006912142,"about_ca_topic_score_gemma":0.000007296841,"teacher_disagreement_score":0.010798565,"about_ca_system_score_codex":0.00006623666,"about_ca_system_score_gemma":0.00035608758,"threshold_uncertainty_score":0.999928},"labels":[],"label_agreement":null},{"id":"W4254392123","doi":"10.1002/cne.23036","title":"Regional and subcellular distribution of the receptor‐targeting protein PIST in the rat central nervous system","year":2012,"lang":"en","type":"article","venue":"The Journal of Comparative Neurology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Biology; Postsynaptic potential; Inhibitory postsynaptic potential; Neuroligin; Neuroscience; Central nervous system; Excitatory postsynaptic potential; Cell biology; Receptor; Biochemistry","score_opus":0.01773127881659367,"score_gpt":0.23529840334984253,"score_spread":0.21756712453324886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254392123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99562865,0.0017591232,0.0013176971,0.0007984646,0.00026616195,0.00019360201,0.0000034309426,9.381504e-7,0.00003193435],"genre_scores_gemma":[0.9995032,0.00003995235,0.00002835633,0.00012196335,0.00028203434,0.0000028976553,0.000005884714,0.000004795775,0.0000109433395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981217,0.0011569557,0.00031113357,0.00006788595,0.00014600645,0.00019635566],"domain_scores_gemma":[0.99931514,0.00006711835,0.00037753815,0.00012764045,0.000079604986,0.0000329818],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010464167,0.00009523824,0.00017588018,0.000013668745,0.00010585537,0.00000789808,0.00026585726,0.000065606204,0.0000046810806],"category_scores_gemma":[0.00003359161,0.000045177338,0.00007011662,0.000071133596,0.00014492031,0.00000709619,0.000052341984,0.00025728025,4.4004832e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004742179,0.00004638755,0.0032329797,0.000012989773,0.000022996734,9.971378e-7,0.00080301805,0.0003959307,0.99214447,0.0019638492,0.0008698497,0.000032314187],"study_design_scores_gemma":[0.0010256817,0.0013655061,0.027832448,0.00006310126,0.00006721537,0.0006601661,0.0024146351,0.0004300892,0.9435206,0.00023078351,0.022216331,0.00017341018],"about_ca_topic_score_codex":0.000007853286,"about_ca_topic_score_gemma":0.000004061036,"teacher_disagreement_score":0.048623838,"about_ca_system_score_codex":0.000009119247,"about_ca_system_score_gemma":0.000032281878,"threshold_uncertainty_score":0.18422784},"labels":[],"label_agreement":null},{"id":"W4254598745","doi":"10.1161/hyp.36.suppl_1.683-d","title":"Dissociation of Direct and Indirect Effects of Angiotensin II on the Heart","year":2000,"lang":"en","type":"article","venue":"Hypertension","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Internal medicine; Angiotensin II; Endocrinology; Renin–angiotensin system; Blood pressure; Chemistry; Stimulation; Heart rate; Myocardial infarction; Genetically modified mouse; Cardiac output; Transgene; Medicine; Biochemistry","score_opus":0.0075544619418515604,"score_gpt":0.19627051976047355,"score_spread":0.188716057818622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254598745","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987331,0.0006061302,0.000007254305,0.00015145283,0.00004729149,0.00010183326,0.0000021459125,0.0000034073103,0.00034739787],"genre_scores_gemma":[0.99918485,0.0002214128,0.00011367028,0.00024546916,0.000037862344,0.0000020076966,0.000008969104,0.0000074407567,0.00017834711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99958056,0.0000554565,0.000091493646,0.00011831354,0.0000823516,0.000071825896],"domain_scores_gemma":[0.99974406,0.000040146067,0.00003934619,0.00012246592,0.000036335652,0.000017671662],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012059515,0.0000622162,0.0001264264,0.000014920982,0.00006183206,0.0000025961958,0.000031284246,0.00006955042,0.000021337673],"category_scores_gemma":[0.00006930726,0.000040251543,0.00005086094,0.000042420797,0.000024691062,0.0000012710095,0.000018176617,0.000028033572,0.0000010733037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003796369,0.000033577933,0.00013379972,0.0000071939785,0.000015606436,3.5715408e-7,0.000041547693,0.0000091842185,0.99415296,0.000018257806,0.0011300322,0.0044195433],"study_design_scores_gemma":[0.00016119432,0.0004121396,0.0046706027,0.000047521422,0.00001550644,0.0000033227905,0.0000088659735,0.000071530274,0.99171424,0.000032322394,0.0028145136,0.000048266233],"about_ca_topic_score_codex":0.000016083983,"about_ca_topic_score_gemma":0.0000014002917,"teacher_disagreement_score":0.0045368033,"about_ca_system_score_codex":0.0000021222363,"about_ca_system_score_gemma":0.0000067216324,"threshold_uncertainty_score":0.16414103},"labels":[],"label_agreement":null},{"id":"W4256086877","doi":"10.7287/peerj.4593v0.2/reviews/2","title":"Peer Review #2 of \"Evolution of dopamine receptors: phylogenetic evidence suggests a later origin of the DRD2l and DRD4rs dopamine receptor gene lineages (v0.2)\"","year":2018,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Dopamine; Phylogenetic tree; Dopamine receptor; Dopamine receptor D3; Gene; Receptor; Biology; Neuroscience; Evolutionary biology; Psychology; Genetics","score_opus":0.02691224181457303,"score_gpt":0.29910154596376454,"score_spread":0.2721893041491915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4256086877","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03364444,0.9516287,0.0009859737,0.008515514,0.0023395384,0.0019707396,0.0005213371,0.000015406718,0.0003783864],"genre_scores_gemma":[0.012944127,0.7892175,0.0052621434,0.0006941838,0.0011011244,0.000097776254,0.0010230847,0.00011616296,0.1895439],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959324,0.00037664472,0.0015006942,0.00081312214,0.0010205393,0.00035662574],"domain_scores_gemma":[0.99418443,0.000084869556,0.0014371981,0.0012082458,0.0029716217,0.00011363173],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0018822517,0.00057258684,0.0013681406,0.00010052549,0.000056599984,0.000011604099,0.00076382846,0.0005291077,0.0015094202],"category_scores_gemma":[0.001911861,0.00038640725,0.0004990278,0.00035632827,0.00039981905,0.000009414062,0.00047457093,0.00025765592,0.000007398307],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042029034,0.00007138066,0.00017572328,0.023450918,0.00018018048,2.8151698e-7,0.000012753218,0.0000027589654,0.62071556,0.000009233667,0.35188332,0.0034558878],"study_design_scores_gemma":[0.00018710177,0.00049413234,0.000032918637,0.028836591,0.0002915651,0.0000116744795,0.0000061290025,0.000005399098,0.47753862,0.0000084360845,0.49229914,0.00028831794],"about_ca_topic_score_codex":0.00016896878,"about_ca_topic_score_gemma":0.00004941191,"teacher_disagreement_score":0.18916552,"about_ca_system_score_codex":0.000045543624,"about_ca_system_score_gemma":0.0003570877,"threshold_uncertainty_score":0.9998588},"labels":[],"label_agreement":null},{"id":"W4280542156","doi":"10.1021/acsomega.1c07226","title":"Functional Characterization of Sodium Channel Inhibitors at the Delta-Opioid Receptor","year":2022,"lang":"en","type":"article","venue":"ACS Omega","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Institute of Neurosciences, Mental Health and Addiction; Natural Sciences and Engineering Research Council of Canada","keywords":"Allosteric regulation; G protein-coupled receptor; Opioid; Receptor; δ-opioid receptor; Opioid receptor; Chemistry; Functional selectivity; Sodium channel; Pharmacology; Allosteric modulator; Medicine; Sodium; Biochemistry","score_opus":0.010117438209916847,"score_gpt":0.20242059709736848,"score_spread":0.19230315888745164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280542156","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99781334,0.0001892078,0.00065313384,0.00028784084,0.0007053688,0.00013495097,0.00010018259,0.000008713243,0.00010723196],"genre_scores_gemma":[0.9936627,0.00006155279,0.000028130256,0.00034261312,0.0003887522,0.00006961749,0.0013501307,0.000017770546,0.0040786956],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992335,0.000059070295,0.00017191634,0.00019808495,0.0001980579,0.0001394077],"domain_scores_gemma":[0.99959534,0.000008183502,0.00011884898,0.00019049081,0.00005693007,0.000030180212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021599735,0.0000912834,0.00008534778,0.000029087456,0.00027831356,0.000009371813,0.00013413346,0.000053094704,0.00038659925],"category_scores_gemma":[0.000018383414,0.00007485648,0.00007285139,0.00010246109,0.00003325303,0.0000036513943,0.00025156996,0.000078567326,0.000011034982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008163791,0.000029536362,0.0001249788,0.0000052722394,0.00002353218,1.9122983e-7,0.00008473056,0.000056513483,0.9926789,0.00008576935,0.0063570035,0.00047196756],"study_design_scores_gemma":[0.00019869763,0.0001516459,0.00029128924,0.000002105682,0.00000734516,0.0000047670096,0.00010640957,0.00002479374,0.8732527,0.000044172415,0.12582962,0.000086440115],"about_ca_topic_score_codex":0.000009115094,"about_ca_topic_score_gemma":0.0000028895033,"teacher_disagreement_score":0.11947262,"about_ca_system_score_codex":0.000025037712,"about_ca_system_score_gemma":0.00004203788,"threshold_uncertainty_score":0.42329907},"labels":[],"label_agreement":null},{"id":"W4280612330","doi":"10.1016/j.ejphar.2022.175043","title":"A systematic analysis of prostaglandin E2 type 3 receptor isoform signaling reveals isoform- and species-dependent L798106 Gαz-biased agonist responses","year":2022,"lang":"en","type":"article","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Gene isoform; G protein-coupled receptor; Receptor; Signal transduction; Agonist; Biology; Prostaglandin E2 receptor; Pharmacology; Cell biology; Biochemistry","score_opus":0.01949411158074132,"score_gpt":0.27147846059503045,"score_spread":0.2519843490142891,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4280612330","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99562114,0.0019215684,0.0010109931,0.00013788173,0.0007275867,0.00027611473,0.000078226476,0.0000057794705,0.00022072758],"genre_scores_gemma":[0.99699044,0.0003144268,0.0005836521,0.00028959705,0.00025924845,0.0000057508464,0.000038966322,0.000034299297,0.0014836038],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964999,0.0016538991,0.0010116393,0.00025045013,0.00031852123,0.00026560767],"domain_scores_gemma":[0.9982365,0.00012578262,0.0011051147,0.00016110984,0.00025048415,0.000121017045],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0036131232,0.00019211567,0.0006316829,0.00038874862,0.00021425929,0.000031097123,0.0003583092,0.000037554008,0.0013356564],"category_scores_gemma":[0.00020744986,0.0001660917,0.0002672264,0.0003869162,0.00007182252,0.000010287905,0.00022908428,0.00026754383,0.0000037019925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013733843,0.00009977657,0.0004205615,0.0003194369,0.001620244,0.00009275075,0.0003800054,0.0010091653,0.9925407,0.000021434427,0.0020560652,0.00006645555],"study_design_scores_gemma":[0.003043851,0.0056010047,0.00075766764,0.00024784158,0.0029500143,0.00035493053,0.0020382926,0.00034536372,0.9733969,0.000015489833,0.010800832,0.00044782067],"about_ca_topic_score_codex":0.0000019513236,"about_ca_topic_score_gemma":7.0349677e-7,"teacher_disagreement_score":0.019143827,"about_ca_system_score_codex":0.000056858124,"about_ca_system_score_gemma":0.000110359535,"threshold_uncertainty_score":0.9995773},"labels":[],"label_agreement":null},{"id":"W4281387249","doi":"10.1038/s41467-022-30570-7","title":"Functional expression of opioid receptors and other human GPCRs in yeast engineered to produce human sterols","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"DEVCOM Army Research Laboratory; Army Research Office; Natural Sciences and Engineering Research Council of Canada; U.S. Army Combat Capabilities Development Command; Army Research Laboratory; National Institutes of Health; National Center for Complementary and Integrative Health; Concordia University; University of Texas at Austin; National Institute of General Medical Sciences; American Heart Association; Fonds de recherche du Québec – Nature et technologies; Welch Foundation","keywords":"Receptor; Sterol; G protein-coupled receptor; Saccharomyces cerevisiae; Biology; Yeast; Ergosterol; Computational biology; Cell biology; Biochemistry; Cholesterol","score_opus":0.02007521466203115,"score_gpt":0.2807295597160671,"score_spread":0.26065434505403595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281387249","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974043,0.0015142655,0.000108905304,0.0002346573,0.00010617084,0.00023116102,0.000045091445,0.000007879566,0.00034757005],"genre_scores_gemma":[0.9975577,0.000017984627,0.001593211,0.0001689351,0.000040385716,0.00009520812,0.00024151853,0.000013989039,0.0002710789],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99940926,0.00009448372,0.00014882958,0.00016466195,0.00010028847,0.00008246297],"domain_scores_gemma":[0.9992829,0.000008700849,0.000051801184,0.0005832079,0.000040969917,0.00003239572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019993431,0.00007056744,0.00008207964,0.00007254416,0.00019703517,0.000007465665,0.0003221141,0.0000862114,0.00012768437],"category_scores_gemma":[0.000026075399,0.0000733863,0.000025171092,0.00010851588,0.000024758909,0.0000026933044,0.00041670696,0.00027915122,6.066853e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012887851,0.00006710498,0.001161926,0.0000044908884,0.0000064287633,4.126223e-8,0.00017813359,0.00013774681,0.9951264,0.0010391974,0.0021255913,0.00014004065],"study_design_scores_gemma":[0.00041101803,0.00020343874,0.004505464,0.000024890138,0.000006643117,0.0000028148945,0.00044030652,0.000017144905,0.81415266,0.00013709978,0.17993416,0.00016436189],"about_ca_topic_score_codex":0.000015394164,"about_ca_topic_score_gemma":0.00006965453,"teacher_disagreement_score":0.18097375,"about_ca_system_score_codex":0.000014843729,"about_ca_system_score_gemma":0.000017445203,"threshold_uncertainty_score":0.29926065},"labels":[],"label_agreement":null},{"id":"W4281718943","doi":"10.1016/j.jbc.2022.102104","title":"Distinct functional roles for the M4 α-helix from each homologous subunit in the heteropentameric ligand-gated ion channel nAChR","year":2022,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Protein subunit; Xenopus; Homologous chromosome; Alanine; Ion channel; Nicotinic acetylcholine receptor; HEK 293 cells; Chemistry; Acetylcholine receptor; Helix (gastropod); Biophysics; Cell biology; Biology; Biochemistry; Receptor; Amino acid; Gene","score_opus":0.026913549493088447,"score_gpt":0.23999549560302733,"score_spread":0.21308194610993889,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281718943","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942023,0.0029031036,0.001915724,0.00048154,0.0002368344,0.00013117725,0.00007299764,0.0000037433372,0.000052551153],"genre_scores_gemma":[0.9982031,0.00019189913,0.00007133468,0.0004131351,0.0007549894,0.00003800535,0.00023003142,0.000010010509,0.00008749367],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99888647,0.00013863649,0.000356938,0.0002097969,0.00020105854,0.00020710476],"domain_scores_gemma":[0.99926287,0.0001643774,0.0002851551,0.00016885958,0.00007357973,0.00004517977],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007093412,0.00014955613,0.00019906119,0.000014710529,0.00026900216,0.000032906974,0.0005114646,0.000120812045,0.00027544887],"category_scores_gemma":[0.00014227608,0.00007863848,0.00023015156,0.00009714241,0.00008074582,0.0000036315434,0.00014576953,0.00038972503,8.578201e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005248659,0.0001422108,0.0005389818,0.0000048683733,0.00006621707,0.000013404205,0.0000536049,0.0004961594,0.9962158,0.0000033735123,0.0010357643,0.00090472697],"study_design_scores_gemma":[0.0013736406,0.0011580555,0.0036232586,0.00001670956,0.000052724667,0.00039124058,0.0024228252,0.00033671962,0.9650865,0.00065663125,0.024622269,0.00025940852],"about_ca_topic_score_codex":0.000013682794,"about_ca_topic_score_gemma":0.0000023601126,"teacher_disagreement_score":0.031129304,"about_ca_system_score_codex":0.00003070958,"about_ca_system_score_gemma":0.00004819339,"threshold_uncertainty_score":0.32067838},"labels":[],"label_agreement":null},{"id":"W4281789731","doi":"10.1101/2022.06.09.495548","title":"Gait Abnormalities and Aberrant D2 Receptor Expression and Signaling in a Mouse Model of the Human Pathogenic Mutation <i> DRD2 <sup>I212F</sup> </i>","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Drug Abuse; York University; Rijksuniversiteit Groningen; Oregon Health and Science University; New York University Abu Dhabi; National Institute of Neurological Disorders and Stroke; Office of Research and Development; U.S. Department of Veterans Affairs","keywords":"Dopamine receptor D2; Dopamine; Nucleus accumbens; Striatum; Sulpiride; Endocrinology; Internal medicine; Dopamine receptor; Neuroscience; Dopamine receptor D1; Biology; Medicine; Dopaminergic","score_opus":0.012087118045899218,"score_gpt":0.21035853892862336,"score_spread":0.19827142088272415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281789731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99630123,0.0017677181,0.00082935457,0.000026243273,0.00012501984,0.0005561805,0.0003615818,0.000028441937,0.000004205016],"genre_scores_gemma":[0.99627125,0.0005074077,0.0027356963,0.00008808557,0.00011859881,0.0001592231,0.000004330045,0.000086361004,0.000029069168],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976983,0.00026742212,0.0005767054,0.00080028997,0.00031113042,0.00034614952],"domain_scores_gemma":[0.9986465,0.000022677848,0.0004054592,0.0006673885,0.00014605655,0.00011189314],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00069497345,0.0004050236,0.00041751435,0.00012960918,0.00025024716,0.00008496059,0.000363708,0.00041318065,0.000040513045],"category_scores_gemma":[0.00007370753,0.00037580566,0.00013348537,0.00012971395,0.000120686054,0.00001743802,0.0008919531,0.00049102464,3.7763166e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039473038,0.000056375146,0.0016536508,0.00026632182,0.000040681163,0.000002289217,0.00012904243,0.011087344,0.98652947,0.00016966042,0.000023769364,0.0000019034558],"study_design_scores_gemma":[0.00056394486,0.00007075833,0.00037188988,0.00022842539,0.00003982974,4.8866706e-8,0.00009009002,0.0036387192,0.99438596,0.000014265089,0.00016253933,0.00043350717],"about_ca_topic_score_codex":0.000056091267,"about_ca_topic_score_gemma":0.0000036248891,"teacher_disagreement_score":0.007856493,"about_ca_system_score_codex":0.000050932398,"about_ca_system_score_gemma":0.00022779829,"threshold_uncertainty_score":0.9998694},"labels":[],"label_agreement":null},{"id":"W4281826548","doi":"10.26434/chemrxiv-2022-bfgzt","title":"Identification of Bioactive Conformational Space of Flexible Endogenous Lipid Mediator Lysophosphoserine Based on Accessible Spaces and Activities of Conformationally Restricted Analogues","year":2022,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Japan Society for the Promotion of Science; Cosmetology Research Foundation; Japan Agency for Medical Research and Development","keywords":"Dihedral angle; Moiety; Chemistry; Molecular dynamics; Ligand (biochemistry); Rational design; Docking (animal); Stereochemistry; Metadynamics; Molecule; Computational chemistry; Receptor; Nanotechnology; Biochemistry; Materials science; Organic chemistry; Hydrogen bond","score_opus":0.018951001506415474,"score_gpt":0.2529660130019945,"score_spread":0.23401501149557902,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281826548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994951,0.00048671092,0.002842792,0.000035960336,0.00022855324,0.00031330693,0.00033914496,0.000009157354,0.0007933465],"genre_scores_gemma":[0.99695104,0.00040114584,0.0008949093,0.000013538969,0.000055006523,0.0000456144,0.0015291682,0.000015928923,0.00009364779],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99867177,0.000048333623,0.0005633032,0.00025026363,0.0003451652,0.00012113752],"domain_scores_gemma":[0.99813277,0.000070129725,0.0011574583,0.00032345526,0.00026990465,0.000046265643],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002619626,0.00019316499,0.00035341998,0.00019693375,0.000053837775,0.00002134378,0.00023956306,0.00019173995,0.00020686376],"category_scores_gemma":[0.00009900538,0.00019597718,0.00012004368,0.00013287405,0.00013312326,0.0000147080045,0.0002264097,0.00014634662,3.0854048e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032334743,0.00010025039,0.00040647105,0.00048509866,0.00016384115,2.9579311e-7,0.00035418104,0.0036043464,0.9932971,0.00096991163,0.000059036363,0.00023612141],"study_design_scores_gemma":[0.0004029874,0.00023770634,0.0010199088,0.00006018703,0.000041758503,0.0000011071517,0.0008608728,0.0017703205,0.9951067,0.00016841303,0.00017216917,0.00015789134],"about_ca_topic_score_codex":0.000066597204,"about_ca_topic_score_gemma":0.000002240372,"teacher_disagreement_score":0.0020000124,"about_ca_system_score_codex":0.000024372832,"about_ca_system_score_gemma":0.0003587743,"threshold_uncertainty_score":0.7991717},"labels":[],"label_agreement":null},{"id":"W4282052768","doi":"10.1002/bmc.5423","title":"Quantitative determination of LY‐404,039, a metabotropic glutamate 2/3 receptor agonist, in rat plasma using chemical derivatization and HPLC–MRM/MS","year":2022,"lang":"en","type":"article","venue":"Biomedical Chromatography","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; Université de Montréal; McGill University; Centre Hospitalier de l’Université de Montréal; Montreal Neurological Institute and Hospital","funders":"Weston Brain Institute","keywords":"Chemistry; Chromatography; Derivatization; Protein precipitation; Formic acid; Pharmacokinetics; Selected reaction monitoring; High-performance liquid chromatography; Extraction (chemistry); Acetonitrile; Tandem mass spectrometry; Mass spectrometry; Pharmacology","score_opus":0.01312130614176136,"score_gpt":0.25383488664837317,"score_spread":0.24071358050661182,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4282052768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855613,0.00051765447,0.0133583145,0.000042577987,0.0002361184,0.00020461524,0.00004247759,0.000012971206,0.000023979905],"genre_scores_gemma":[0.97599983,0.00008776992,0.023484811,0.0000454546,0.00005903765,0.00004257324,0.0002505942,0.00002287581,0.0000070468554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985766,0.00015032015,0.00039076334,0.00035456775,0.00030475148,0.00022303336],"domain_scores_gemma":[0.99950564,0.000027580276,0.00018181246,0.00014358555,0.000047699737,0.00009370687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026517513,0.00016208038,0.00025281153,0.00024062546,0.00011063336,0.00001879505,0.00014576897,0.00013180495,0.00011351715],"category_scores_gemma":[0.00006458681,0.00016240744,0.00010218333,0.0005511861,0.00019472075,0.00000994897,0.00015875963,0.00011229346,4.773775e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001127437,0.00012210417,0.0010646918,0.00005268954,0.00002825207,0.0000035140117,0.000110173394,0.000008816059,0.99616635,0.000336605,0.000060270846,0.0019337826],"study_design_scores_gemma":[0.0014070641,0.0007951349,0.00040729842,0.00005114346,0.000038489998,0.000031855754,0.0003297786,0.010566374,0.97975636,0.00027209058,0.006025509,0.00031890091],"about_ca_topic_score_codex":0.000039213748,"about_ca_topic_score_gemma":0.0000041865424,"teacher_disagreement_score":0.016409997,"about_ca_system_score_codex":0.00002298287,"about_ca_system_score_gemma":0.000062882515,"threshold_uncertainty_score":0.6622783},"labels":[],"label_agreement":null},{"id":"W4283278050","doi":"10.1101/2022.06.20.496737","title":"Chrna5 and lynx prototoxins identify acetylcholine super-responder subplate neurons","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; University of Toronto","funders":"Canadian Institutes of Health Research; University of Toronto","keywords":"Cholinergic; Neuroscience; Biology; Nicotinic acetylcholine receptor; Nicotinic agonist; Acetylcholine; Acetylcholine receptor; Population; Transcriptome; Receptor; Gene; Genetics; Gene expression; Pharmacology; Medicine","score_opus":0.013557441469815634,"score_gpt":0.24409313562982832,"score_spread":0.23053569416001268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283278050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933208,0.0021716722,0.0011939574,0.00017832083,0.0011683769,0.0014654136,0.0003616021,0.00012767155,0.000012149356],"genre_scores_gemma":[0.99518484,0.0009421167,0.0018465258,0.00039774337,0.00067921606,0.00062699383,0.00000620502,0.00022037284,0.00009598748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9965899,0.0002566508,0.0005527807,0.0015155366,0.000421383,0.00066372345],"domain_scores_gemma":[0.9977594,0.000019398587,0.00030683234,0.0013513786,0.00023374418,0.000329263],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006862779,0.0006663015,0.0005268913,0.00021044633,0.00035072007,0.00027944922,0.00067829044,0.0006251749,0.00046274156],"category_scores_gemma":[0.00016901469,0.0007350569,0.000231109,0.0002393533,0.00011714127,0.00001599887,0.0017242603,0.00091567315,0.000016696269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009351883,0.00009718283,0.0018311474,0.00016841733,0.00014717168,0.000042715717,0.000008415177,0.00010887321,0.9969399,0.00014086503,0.00041968608,0.0000020945956],"study_design_scores_gemma":[0.0007306375,0.00018508104,0.010968286,0.00007532155,0.00009100058,1.7457553e-7,0.0000071590357,0.00014550259,0.92718524,0.0000029451594,0.0596986,0.00091004965],"about_ca_topic_score_codex":0.000034766923,"about_ca_topic_score_gemma":0.0000039572096,"teacher_disagreement_score":0.06975467,"about_ca_system_score_codex":0.00006523323,"about_ca_system_score_gemma":0.00045292097,"threshold_uncertainty_score":0.99951005},"labels":[],"label_agreement":null},{"id":"W4283330468","doi":"10.1111/bph.15901","title":"α and β catalytic subunits of cAMP‐dependent protein kinase regulate formoterol‐induced inflammatory gene expression changes in human bronchial epithelial cells","year":2022,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Formoterol; Gene expression; Gene knockdown; Biology; Forskolin; Gene silencing; Formoterol Fumarate; Small hairpin RNA; Transcriptome; Regulation of gene expression; Cell biology; RNA interference; Gene; Molecular biology; Endocrinology; Genetics; RNA; Receptor","score_opus":0.0091984473891476,"score_gpt":0.24141704785864093,"score_spread":0.23221860046949333,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283330468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99827486,0.00089125993,0.00006550956,0.00004868006,0.000401908,0.0002636528,0.000045092103,0.0000022265206,0.000006807311],"genre_scores_gemma":[0.9991349,0.00016253462,0.00015444141,0.00008041144,0.00033544877,0.000022427388,0.000018763869,0.000020340452,0.000070741546],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998708,0.00026430874,0.00042132434,0.00018892996,0.00019293888,0.00022451376],"domain_scores_gemma":[0.99936235,0.000008814207,0.00040233758,0.00006058109,0.000082555096,0.00008334478],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062482664,0.000116796684,0.00025257698,0.00012252165,0.00012875134,0.0000130463395,0.00020802469,0.00009462097,0.00019961988],"category_scores_gemma":[0.00001214461,0.00013855803,0.00006254304,0.000052222207,0.00004439198,0.000012128792,0.00022181869,0.00026445842,1.6856032e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003238404,0.00010551429,0.000023072871,0.00003465557,0.00003586116,0.00039472364,0.00010913819,0.00021256616,0.9960454,0.0000033891956,0.00018069908,0.0025311047],"study_design_scores_gemma":[0.0025708268,0.0009550956,0.00014051438,0.00003996117,0.000026774484,0.0008923501,0.0000903243,0.00002122203,0.99452925,0.000053985037,0.00055024744,0.00012945502],"about_ca_topic_score_codex":0.00005651567,"about_ca_topic_score_gemma":0.00006925786,"teacher_disagreement_score":0.0024016495,"about_ca_system_score_codex":0.000037058482,"about_ca_system_score_gemma":0.00008986442,"threshold_uncertainty_score":0.56502324},"labels":[],"label_agreement":null},{"id":"W4283376333","doi":"10.3390/ph15070768","title":"Novel Potent and Selective Agonists of the GPR55 Receptor Based on the 3-Benzylquinolin-2(1H)-One Scaffold","year":2022,"lang":"en","type":"article","venue":"Pharmaceuticals","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Università di Pisa","keywords":"Cannabinoid receptor; Synthetic cannabinoids; Cannabinoid; Receptor; Agonist; Cannabinoid receptor type 2; Neuroinflammation; Pharmacology; Computational biology; Microglia; Chemistry; Mechanism (biology); Biology; Biochemistry; Inflammation; Immunology","score_opus":0.035807436301838066,"score_gpt":0.28020395566782136,"score_spread":0.24439651936598328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283376333","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9832495,0.0011320121,0.0048987395,0.0069663976,0.0006588947,0.001092105,0.0002781495,0.000020965786,0.0017032707],"genre_scores_gemma":[0.99574924,0.000060826194,0.00043537136,0.003330395,0.00011048866,0.000079305944,0.000017190692,0.000021403215,0.0001957648],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875563,0.00020356408,0.00019438374,0.0002918571,0.00032265508,0.0002319054],"domain_scores_gemma":[0.9994067,0.000073352894,0.00009981392,0.00028403304,0.0000659034,0.00007023087],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056414085,0.00013932318,0.00014149788,0.000023883362,0.0003312581,0.00002022421,0.00031456866,0.000051899646,0.00048070622],"category_scores_gemma":[0.00007649025,0.00009149381,0.00010323484,0.00013875289,0.00010396002,0.0000018519638,0.00026957688,0.00020756888,0.0000030911744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014355389,0.00017198532,0.000086263244,0.000010892243,0.00005554078,2.150071e-7,0.000049135633,0.00049275125,0.99478406,0.0012750523,0.001392533,0.0015380009],"study_design_scores_gemma":[0.00054883835,0.00021582983,0.00013708402,0.000010000074,0.0000351493,0.0000043959885,0.000081945494,0.0023522612,0.9726619,0.00012374918,0.02370407,0.00012473694],"about_ca_topic_score_codex":0.000010682678,"about_ca_topic_score_gemma":0.0000011884437,"teacher_disagreement_score":0.022311537,"about_ca_system_score_codex":0.00002500997,"about_ca_system_score_gemma":0.000074757765,"threshold_uncertainty_score":0.5263396},"labels":[],"label_agreement":null},{"id":"W4283513535","doi":"10.1016/j.pharmthera.2022.108236","title":"Clozapine’s multiple cellular mechanisms: What do we know after more than fifty years? A systematic review and critical assessment of translational mechanisms relevant for innovative strategies in treatment-resistant schizophrenia","year":2022,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Clozapine; Antipsychotic; Neuroscience; Schizophrenia (object-oriented programming); Pharmacology; Dopamine receptor D2; Medicine; Bioinformatics; Computational biology; Psychology; Biology; Dopamine; Psychiatry","score_opus":0.039409106150187084,"score_gpt":0.3724288141002001,"score_spread":0.333019707950013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283513535","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012341453,0.98415816,0.010806112,0.00017214047,0.00035608796,0.0038674083,0.0005024191,0.000012651629,0.0000016377052],"genre_scores_gemma":[0.0016735673,0.9877848,0.0061342153,0.00033204167,0.00006828177,0.003455136,0.000434946,0.00009389958,0.000023131752],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.99673855,0.0007390783,0.0011493595,0.00071208354,0.0002573542,0.00040354882],"domain_scores_gemma":[0.99857974,0.00037482905,0.0004903243,0.0003212373,0.0001556368,0.00007822414],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00069917133,0.0006067762,0.002054242,0.00019043854,0.000094193245,0.000063352134,0.00030609392,0.00037711472,0.00024272958],"category_scores_gemma":[0.00001666236,0.0005042024,0.00043351497,0.00027182212,0.000117315205,0.000026329359,0.000104457125,0.00032211005,7.2114506e-7],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00085561373,0.0012619368,9.4212743e-7,0.70078707,0.0070164907,0.00009266747,0.00075910415,0.000023416807,0.15329711,0.011008149,0.000027164657,0.124870345],"study_design_scores_gemma":[0.009225545,0.0069861277,0.0000026280418,0.20649016,0.045398723,0.00013739675,0.0031360805,0.0011779625,0.021107178,0.010862379,0.6920046,0.0034711887],"about_ca_topic_score_codex":0.0000034891289,"about_ca_topic_score_gemma":0.000008304884,"teacher_disagreement_score":0.69197744,"about_ca_system_score_codex":0.00011024961,"about_ca_system_score_gemma":0.0006294463,"threshold_uncertainty_score":0.99974096},"labels":[],"label_agreement":null},{"id":"W4283747045","doi":"10.1371/journal.pone.0269404","title":"An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age","year":2022,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Alliance for Research on Schizophrenia and Depression; McGill University; Tulane University; Louisiana Board of Regents; Brain and Behavior Research Foundation","keywords":"Neuroscience; Long-term potentiation; Synaptic plasticity; AMPA receptor; Biology; Neuroplasticity; Postsynaptic potential; Hippocampus; Synapse; Metaplasticity; Gating; Glutamate receptor; Genetics; Receptor","score_opus":0.020433026680326576,"score_gpt":0.2142359732743602,"score_spread":0.19380294659403363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283747045","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99788475,0.0000848692,0.0015415376,0.000029692415,0.000038805512,0.00014539243,0.000019122479,0.000026663054,0.00022917245],"genre_scores_gemma":[0.9936488,0.00001023566,0.0055408897,0.00014990069,0.00014568176,0.000041249128,0.00011308044,0.000037427242,0.00031268274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989923,0.000079337355,0.00014592802,0.00034410582,0.00020108167,0.00023719519],"domain_scores_gemma":[0.99956286,0.000018220144,0.000079580044,0.00021390281,0.00004544642,0.00007999539],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011879054,0.00013616636,0.00015950856,0.00003400925,0.00023388873,0.000040733084,0.00020110287,0.000042165942,0.0004057988],"category_scores_gemma":[0.000036125897,0.00012805319,0.000039223145,0.000063013424,0.000026795196,0.000005673692,0.00013321392,0.00017256172,0.000007768729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014176409,0.00050168147,0.0005741786,0.000019125842,0.00022436553,0.000025901909,0.00010379066,0.0017721889,0.9964565,0.000023140989,0.000029607341,0.00012777012],"study_design_scores_gemma":[0.00032732758,0.0012039408,0.00010512153,0.00003825274,0.00006603992,0.000017750512,0.0003078866,0.003897798,0.99352694,0.000029281371,0.00025208475,0.00022759968],"about_ca_topic_score_codex":0.000033437987,"about_ca_topic_score_gemma":0.000018005509,"teacher_disagreement_score":0.0042358926,"about_ca_system_score_codex":0.00002337131,"about_ca_system_score_gemma":0.000028611734,"threshold_uncertainty_score":0.52218574},"labels":[],"label_agreement":null},{"id":"W4283792693","doi":"10.1124/molpharm.122.000497","title":"Michaelis-Menten Quantification of Ligand Signaling Bias Applied to the Promiscuous Vasopressin V2 Receptor","year":2022,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Ligand (biochemistry); Agonist; Vasopressin; G protein-coupled receptor; Receptor; Affinities; Intrinsic activity; Chemistry; Biology; Biophysics; Biochemistry; Endocrinology","score_opus":0.020293417456215813,"score_gpt":0.2698263718320222,"score_spread":0.24953295437580636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283792693","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9784844,0.0008298118,0.017876264,0.0010504179,0.0006531952,0.00082741195,0.00004424916,0.000017715098,0.00021651667],"genre_scores_gemma":[0.9958548,0.000028605225,0.001208453,0.0018027624,0.00017873022,0.00047208517,0.00016916242,0.00004188986,0.00024354213],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983666,0.00028621635,0.00034258858,0.00045671174,0.00024920373,0.00029866144],"domain_scores_gemma":[0.9992934,0.000021109723,0.00019524149,0.00032038876,0.00008638609,0.00008349381],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00067402935,0.00017834574,0.00020799953,0.00007834929,0.00024962678,0.000017604405,0.00048371512,0.00007879148,0.0005423596],"category_scores_gemma":[0.000027558257,0.00015579631,0.00011934731,0.0002098634,0.000049229602,0.0000021963367,0.00034962982,0.00017839913,0.000015238574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002444241,0.00010772047,0.000016539558,0.0000141025275,0.00012728818,0.0000035711735,0.00024304067,0.013609415,0.97793543,0.00019769702,0.0062455,0.0012552745],"study_design_scores_gemma":[0.0005423168,0.00028585774,0.00000667971,0.0000030064077,0.00005482097,0.000008242773,0.00022581518,0.00020832928,0.9061536,0.000039414568,0.09230819,0.00016369461],"about_ca_topic_score_codex":0.000016016766,"about_ca_topic_score_gemma":0.0000015282545,"teacher_disagreement_score":0.08606269,"about_ca_system_score_codex":0.000027284585,"about_ca_system_score_gemma":0.00008200622,"threshold_uncertainty_score":0.6353189},"labels":[],"label_agreement":null},{"id":"W4284711655","doi":"10.1016/j.celrep.2022.111031","title":"EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks","year":2022,"lang":"en","type":"article","venue":"Cell Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval; PROTEO; Centre hospitalier universitaire de Québec","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canada Foundation for Innovation","keywords":"Erythropoietin-producing hepatocellular (Eph) receptor; Scaffold protein; Cell biology; Ephrin; Phosphorylation; Receptor tyrosine kinase; Proto-oncogene tyrosine-protein kinase Src; Signal transduction; Kinase; Biology; Cell migration; Cell signaling; Cell adhesion; Receptor; Chemistry; Cell; Biochemistry","score_opus":0.006571761459467985,"score_gpt":0.20091604456486348,"score_spread":0.1943442831053955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4284711655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99344516,0.0014864985,0.0027134556,0.0001516059,0.0007545015,0.00077700877,0.000008318733,0.000038730515,0.00062472123],"genre_scores_gemma":[0.99208313,0.000038025428,0.0008902614,0.00039878444,0.0003750526,0.00031547074,0.00016177511,0.00005830698,0.00567921],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803436,0.00011393059,0.00044906366,0.00064672966,0.00030986205,0.00044603538],"domain_scores_gemma":[0.9987933,0.0000119154165,0.00027408465,0.0006846244,0.000079522244,0.00015657283],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068831246,0.0002523029,0.00021198858,0.000038308197,0.00056946435,0.0000710288,0.00025374972,0.00010008181,0.00077746937],"category_scores_gemma":[0.000041588748,0.00018594186,0.00017423976,0.00022229583,0.000036760357,0.0000045783727,0.00038615623,0.00019714634,0.000008253306],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007091481,0.00006937773,0.00017546448,0.0000072125517,0.000027211605,0.00007538719,0.000048803962,0.038836826,0.9534459,0.00000806263,0.0035915812,0.0036432166],"study_design_scores_gemma":[0.00013576049,0.00030088003,0.000021523088,0.00001695586,0.00001838078,0.000060620092,0.00009816625,0.00038621415,0.90085495,0.00008186842,0.09774721,0.00027747016],"about_ca_topic_score_codex":0.00005637862,"about_ca_topic_score_gemma":0.0000040776213,"teacher_disagreement_score":0.09415563,"about_ca_system_score_codex":0.000038786216,"about_ca_system_score_gemma":0.000080071455,"threshold_uncertainty_score":0.85127443},"labels":[],"label_agreement":null},{"id":"W4285395429","doi":"10.3390/cells11142185","title":"The Succinate Receptor SUCNR1 Resides at the Endoplasmic Reticulum and Relocates to the Plasma Membrane in Hypoxic Conditions","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Université de Sherbrooke; Centre Hospitalier Universitaire Sainte-Justine; Hôpital Maisonneuve-Rosemont; Université de Montréal; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Endoplasmic reticulum; Cell biology; G protein-coupled receptor; Signal transduction; Biology; Receptor; STIM1; Biochemistry","score_opus":0.0047682668446542885,"score_gpt":0.20246595117575392,"score_spread":0.19769768433109963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285395429","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925244,0.001130635,0.000009695348,0.004991333,0.0003855093,0.0003671838,0.000053549586,0.000007056893,0.00053064886],"genre_scores_gemma":[0.99203044,0.00070060376,0.00004135491,0.0005735958,0.000082678154,0.00016408457,0.00005006665,0.000019596471,0.006337598],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892396,0.00022043056,0.00018097306,0.00027363072,0.00014437413,0.0002566085],"domain_scores_gemma":[0.99934477,0.00016561702,0.0000599805,0.00035384053,0.00002710012,0.00004867052],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006140707,0.00012103159,0.00009400015,0.000024483435,0.0009553019,0.000052880026,0.0003125659,0.00004551074,0.00032075387],"category_scores_gemma":[0.00006759219,0.000067335845,0.000050986197,0.0001393862,0.00009672397,0.0000023355626,0.00035963475,0.00015995509,0.000032047938],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006396019,0.000011369422,0.000051012674,0.0000041113444,0.000016348364,0.0000021260655,0.00028200823,0.001257581,0.9837941,0.00033331753,0.0139534455,0.00023061057],"study_design_scores_gemma":[0.00017726782,0.000109289635,0.000059041235,0.000004378593,0.0000072666285,0.000015004475,0.00078044104,0.00011325989,0.76055497,0.00010414494,0.23799014,0.00008481932],"about_ca_topic_score_codex":0.000052300285,"about_ca_topic_score_gemma":0.00031242738,"teacher_disagreement_score":0.2240367,"about_ca_system_score_codex":0.000026049991,"about_ca_system_score_gemma":0.000036236677,"threshold_uncertainty_score":0.7347507},"labels":[],"label_agreement":null},{"id":"W4285596414","doi":"10.51731/cjht.2022.392","title":"Trace Amine-Associated Receptor 1 Agonists for Schizophrenia","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Antipsychotic; Medicine; Partial agonist; Agonist; Pharmacology; Clinical trial; Dopamine receptor D2; Schizophrenia (object-oriented programming); Internal medicine; Psychiatry; Dopamine; Receptor","score_opus":0.01674535363351529,"score_gpt":0.2506839181679237,"score_spread":0.2339385645344084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285596414","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9351109,0.050128166,0.002699201,0.009984416,0.0013145278,0.000414175,0.00026931215,0.00004436732,0.000034922876],"genre_scores_gemma":[0.9970971,0.000191977,0.0021373066,0.00026539975,0.000029370245,0.00003100509,0.000044143,0.000022385366,0.00018134696],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99883914,0.00007500966,0.0004034723,0.00016080287,0.00011627053,0.00040530204],"domain_scores_gemma":[0.9991859,0.000016860311,0.0004184589,0.00016759489,0.0001344342,0.0000767502],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00083964935,0.00011376201,0.00023920748,0.0002113191,0.0006086633,0.00002613602,0.00041760397,0.000120680095,0.0000643607],"category_scores_gemma":[0.0004539341,0.000114136754,0.0001270656,0.00016555007,0.00006209825,0.0000042874476,0.000038323455,0.0002712644,8.0167604e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034139102,0.00011394671,0.0011920322,0.00010176624,0.00031081826,0.000037433925,0.00039136675,0.0007346335,0.32153693,0.0023209876,0.110466875,0.56245184],"study_design_scores_gemma":[0.0010692747,0.0024509437,0.00018392869,0.000036593225,0.000011609961,0.000096524185,0.002961738,0.000026206742,0.06319462,0.0017560087,0.927968,0.00024451327],"about_ca_topic_score_codex":0.00037404883,"about_ca_topic_score_gemma":0.00071286695,"teacher_disagreement_score":0.8175012,"about_ca_system_score_codex":0.00021764365,"about_ca_system_score_gemma":0.0017387521,"threshold_uncertainty_score":0.46814075},"labels":[],"label_agreement":null},{"id":"W4285605340","doi":"10.1016/j.bpj.2022.07.015","title":"Multisite phosphorylation and binding alter conformational dynamics of the 4E-BP2 protein","year":2022,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Dynamics (music); Phosphorylation; Biophysics; Chemistry; Cell biology; Biology; Biochemistry; Physics","score_opus":0.006042615044821924,"score_gpt":0.21515034596369076,"score_spread":0.20910773091886883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285605340","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99662256,0.000022917477,0.002909803,0.00014776833,0.00012697354,0.00009071813,0.000026147909,0.000001467103,0.000051617048],"genre_scores_gemma":[0.9992157,0.0000057205443,0.00041959604,0.000050062088,0.00011773436,0.000005801966,0.000025012818,0.000005926394,0.00015442616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999464,0.00004851788,0.00014562067,0.00007524621,0.00018047399,0.0000861423],"domain_scores_gemma":[0.99972683,0.0000045726306,0.00012981959,0.00006543485,0.000039409202,0.00003394703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013874189,0.000056724057,0.00006347676,0.000016582639,0.00024380589,0.000021010334,0.000099797355,0.00002698362,0.00007311828],"category_scores_gemma":[0.000012525093,0.00004149085,0.00006809086,0.000048614576,0.000032911114,0.0000052486903,0.000118849865,0.00013761783,7.00429e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032910957,0.000022570292,0.0002378598,0.00000366648,0.000015261181,3.755709e-7,0.000034480134,0.00017487557,0.9966186,0.0013234282,0.000040469182,0.0014954533],"study_design_scores_gemma":[0.00037430166,0.0001762973,0.0007475193,0.0000101275145,0.000008651728,0.000047751106,0.0001516677,0.0077084242,0.9893112,0.00028164082,0.0010963045,0.00008610192],"about_ca_topic_score_codex":0.0000035151463,"about_ca_topic_score_gemma":8.15794e-7,"teacher_disagreement_score":0.007533549,"about_ca_system_score_codex":0.000020121588,"about_ca_system_score_gemma":0.000023217242,"threshold_uncertainty_score":0.18751824},"labels":[],"label_agreement":null},{"id":"W4286268417","doi":"10.1016/j.jbc.2022.102294","title":"Prostaglandin F2α and angiotensin II type 1 receptors exhibit differential cognate G protein coupling regulation","year":2022,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Tohoku University; McGill University","keywords":"G protein-coupled receptor; Receptor; Allosteric regulation; G protein; Functional selectivity; Signal transduction; Angiotensin II; Gq alpha subunit; Cell biology; Chemistry; Biophysics; Biology; Ligand (biochemistry); Biochemistry","score_opus":0.015184305678432142,"score_gpt":0.22632372399486933,"score_spread":0.21113941831643718,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286268417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99823266,0.00080255215,0.0004388239,0.0002066114,0.00017524479,0.00010541939,0.000009188858,0.000006477114,0.000023000499],"genre_scores_gemma":[0.9981983,0.000090648966,0.0005415598,0.000032382257,0.00040405494,0.0000050409867,0.00008420406,0.000011731483,0.0006320776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991344,0.00003965764,0.00026349118,0.00021306176,0.0001775793,0.00017177527],"domain_scores_gemma":[0.99938285,0.00000938681,0.00029562815,0.000096409436,0.00012470347,0.00009100971],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003150198,0.00013517757,0.00020009895,0.000020611677,0.0002284499,0.00002719856,0.00012861376,0.00015356083,0.00045983444],"category_scores_gemma":[0.00009575951,0.000103545826,0.000100480436,0.00007461027,0.00005394452,0.000004564286,0.00021643963,0.00025039128,2.4830027e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003758465,0.000052724346,0.00035097342,0.000010002701,0.000034909834,0.0000065942672,0.000020796833,0.00010007183,0.9979305,0.0000060813045,0.00074437633,0.00036707916],"study_design_scores_gemma":[0.00055529265,0.0009112244,0.00019460227,0.000020008825,0.000014493308,0.00012719439,0.00014097255,0.00017846812,0.98578715,0.00014097044,0.011771561,0.00015807763],"about_ca_topic_score_codex":7.6398356e-7,"about_ca_topic_score_gemma":9.239027e-8,"teacher_disagreement_score":0.012143409,"about_ca_system_score_codex":0.000025999454,"about_ca_system_score_gemma":0.00004047227,"threshold_uncertainty_score":0.50348645},"labels":[],"label_agreement":null},{"id":"W4286300780","doi":"10.7554/elife.78982.sa1","title":"Decision letter: Conformational fingerprinting of allosteric modulators in metabotropic glutamate receptor 2","year":2022,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; McGill University","funders":"","keywords":"Allosteric regulation; Metabotropic glutamate receptor; Metabotropic glutamate receptor 2; Metabotropic glutamate receptor 5; Chemistry; Metabotropic glutamate receptor 4; Metabotropic receptor; Computer science; Neuroscience; Glutamate receptor; Biochemistry; Receptor; Biology","score_opus":0.013238706235755588,"score_gpt":0.2694374780996291,"score_spread":0.2561987718638735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286300780","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.70790887,0.18059495,0.033492055,0.013444611,0.038037114,0.0056531243,0.0022415072,0.00014473131,0.01848303],"genre_scores_gemma":[0.26151755,0.15902415,0.13175832,0.05075323,0.006792921,0.0016422126,0.052601375,0.0010355312,0.33487472],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99783295,0.000106657906,0.0008715261,0.00043569697,0.00048299885,0.00027018806],"domain_scores_gemma":[0.99892247,0.000031396183,0.00045471592,0.00040857407,0.00012901997,0.000053835298],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00061274075,0.00029868115,0.0005997416,0.00015504347,0.00005610771,0.00001976792,0.0004063721,0.00023517053,0.008519161],"category_scores_gemma":[0.00014900134,0.00027736987,0.0002873522,0.00017749716,0.000024899442,0.0000061821675,0.00044019963,0.00027690118,0.000015942003],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000092179966,0.00011417594,0.00006728666,0.00200287,0.00021522457,0.0000056130702,0.000038601615,0.0011450145,0.27765602,0.00025043084,0.6820131,0.036399458],"study_design_scores_gemma":[0.00028788284,0.00011554044,0.000019518262,0.00060094945,0.00003289161,0.000006367496,0.000011433352,0.00014090809,0.025449205,0.000036108813,0.9729936,0.00030560466],"about_ca_topic_score_codex":0.00005830688,"about_ca_topic_score_gemma":0.000019192594,"teacher_disagreement_score":0.4463913,"about_ca_system_score_codex":0.000040782466,"about_ca_system_score_gemma":0.00013175262,"threshold_uncertainty_score":0.9999679},"labels":[],"label_agreement":null},{"id":"W4286851671","doi":"10.3791/2432-v","title":"Hyperinsulinemic-Euglycemic Clamp in the Conscious Rat","year":2011,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Clamp; Internal medicine; Insulin; Endocrinology; Medicine","score_opus":0.0386584591444005,"score_gpt":0.3739916147911482,"score_spread":0.3353331556467477,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4286851671","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956481,0.0018766423,0.001021899,0.000019704732,0.00045693916,0.00010295766,9.3134355e-7,0.0000023147347,0.00087051734],"genre_scores_gemma":[0.9963617,0.00031347727,0.0025738177,0.00045013026,0.00020129586,0.0000064700976,0.0000035806556,0.000015347747,0.000074224015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896204,0.00012196125,0.00041479015,0.00012435681,0.00019758921,0.00017923028],"domain_scores_gemma":[0.9994583,0.000009514591,0.00023110099,0.00016822977,0.00007564112,0.00005719949],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042533624,0.00012371225,0.00018525324,0.00006225437,0.000042450858,0.000019359853,0.00032567937,0.00009725025,0.00017881664],"category_scores_gemma":[0.000045884422,0.00008291303,0.00012569767,0.00007358022,0.00003772681,0.000007127907,0.00004225684,0.00012988216,0.0000058860846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046229613,0.00016859175,0.00039448048,0.000002846327,0.00003315298,0.000028548366,0.0014174212,0.0000025010931,0.99632275,0.00011122566,0.0007246922,0.000331474],"study_design_scores_gemma":[0.0018999792,0.0006028194,0.00009000277,0.00002359736,0.000011019764,0.00015480552,0.0014469466,0.000010525351,0.9856094,0.00014932103,0.00988885,0.00011273444],"about_ca_topic_score_codex":0.000011648071,"about_ca_topic_score_gemma":0.0000014897325,"teacher_disagreement_score":0.010713371,"about_ca_system_score_codex":0.0000151635195,"about_ca_system_score_gemma":0.000057445868,"threshold_uncertainty_score":0.33810952},"labels":[],"label_agreement":null},{"id":"W4288065553","doi":"10.7554/elife.75398.sa1","title":"Decision letter: Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2","year":2021,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"mTORC1; mTORC2; Dopamine; Neuroscience; Biology; Cell biology; PI3K/AKT/mTOR pathway; Signal transduction","score_opus":0.011581345035251775,"score_gpt":0.2502582193896901,"score_spread":0.23867687435443835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288065553","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14544892,0.7805329,0.04220627,0.019274218,0.0076050134,0.0024570983,0.0008754965,0.000071981754,0.0015281362],"genre_scores_gemma":[0.04488014,0.36131987,0.0033622254,0.040509555,0.0037925257,0.00030280525,0.011105349,0.00036940922,0.53435814],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975827,0.00019294639,0.0005550253,0.0010413991,0.00027331783,0.00035462185],"domain_scores_gemma":[0.99876165,0.0000670628,0.00031863956,0.00048298403,0.0001908624,0.00017880565],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00027078818,0.0005347383,0.0012353705,0.00005788351,0.000093868046,0.00009651425,0.00021519413,0.0006115195,0.00052111136],"category_scores_gemma":[0.00019350018,0.00042488368,0.0002342981,0.000045521694,0.000074867465,0.0000030634656,0.00040255985,0.00029645712,0.000004094834],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011644421,0.000039588966,0.000014815375,0.00032627687,0.00012781046,0.000028743842,0.0000017733033,5.651215e-7,0.2820466,0.000007408772,0.709188,0.008102016],"study_design_scores_gemma":[0.0028304725,0.00032667638,0.000022201884,0.0005698492,0.00024455212,0.00008169371,0.00000650683,0.000018126926,0.0163836,0.000014183135,0.9790081,0.0004940658],"about_ca_topic_score_codex":0.00003583024,"about_ca_topic_score_gemma":0.00006179508,"teacher_disagreement_score":0.53283,"about_ca_system_score_codex":0.000010780944,"about_ca_system_score_gemma":0.00005432787,"threshold_uncertainty_score":0.9998203},"labels":[],"label_agreement":null},{"id":"W4288443351","doi":"10.1101/2022.07.26.501653","title":"Proteins with multiple G protein-coupled receptor domains","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Tel Aviv University; Israel Science Foundation","keywords":"G protein-coupled receptor; Transmembrane domain; Transmembrane protein; Computational biology; Biology; Receptor; Chemokine receptor; Signal transduction; Membrane protein; Cell biology; Chemokine; Genetics; Membrane","score_opus":0.008106916943934495,"score_gpt":0.20114633793610343,"score_spread":0.19303942099216892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4288443351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9836657,0.0008136716,0.011457735,0.00009869462,0.0006534669,0.0027434516,0.00034421618,0.00020655459,0.000016505779],"genre_scores_gemma":[0.96693534,0.00011449471,0.029533444,0.00014569795,0.00082387513,0.0020588744,0.000009364786,0.00029413417,0.00008477741],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99626267,0.00021592075,0.0005364727,0.0016176006,0.0005994947,0.00076785515],"domain_scores_gemma":[0.99702895,0.000015543601,0.000529697,0.0017235873,0.0003770761,0.0003251471],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005961046,0.0007846292,0.0005978306,0.00016644219,0.00040174878,0.0001922102,0.00086249335,0.0006496646,0.00063149945],"category_scores_gemma":[0.00017956794,0.0007664444,0.00025416206,0.00031945083,0.00012008639,0.000011603442,0.0010324937,0.00090594986,0.00003251674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025275446,0.0001871044,0.0012534295,0.00021244212,0.00026347698,0.000028086379,0.000006797911,0.0002999943,0.99709505,0.00020846953,0.00019124751,0.0000011766872],"study_design_scores_gemma":[0.0010746703,0.0005023139,0.0009312231,0.00018895608,0.00006438479,3.6158784e-8,0.000010242607,0.00022088244,0.96117926,0.0000014154034,0.03471419,0.0011124182],"about_ca_topic_score_codex":0.000084023886,"about_ca_topic_score_gemma":0.000011819861,"teacher_disagreement_score":0.03591575,"about_ca_system_score_codex":0.00014646047,"about_ca_system_score_gemma":0.00091986835,"threshold_uncertainty_score":0.99947864},"labels":[],"label_agreement":null},{"id":"W4289348296","doi":"10.3390/molecules27154854","title":"Actions of Novel Angiotensin Receptor Blocking Drugs, Bisartans, Relevant for COVID-19 Therapy: Biased Agonism at Angiotensin Receptors and the Beneficial Effects of Neprilysin in the Renin Angiotensin System","year":2022,"lang":"en","type":"article","venue":"Molecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Receptor; Angiotensin II receptor type 1; Angiotensin II; Chemistry; Agonist; Pharmacology; Angiotensin receptor; Inverse agonist; Renin–angiotensin system; G protein-coupled receptor; Internal medicine; Endocrinology; Biology; Biochemistry; Medicine","score_opus":0.018698215077268904,"score_gpt":0.2512304376016289,"score_spread":0.23253222252435998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289348296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98504704,0.0041384073,0.006082126,0.002678046,0.0004679208,0.0014064062,0.00014542732,0.000019967054,0.000014650637],"genre_scores_gemma":[0.9947487,0.00023406361,0.003723756,0.0007181592,0.00014837644,0.00014434436,0.0001762299,0.000052293,0.00005405316],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977024,0.0005682408,0.00053509546,0.00050097547,0.00035437004,0.00033891224],"domain_scores_gemma":[0.99844337,0.00045448978,0.00039882268,0.00050859904,0.00012021837,0.000074510455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012866006,0.0002794109,0.00046957392,0.0001533038,0.0005097608,0.000030183823,0.00033687623,0.00016740775,0.000009970798],"category_scores_gemma":[0.0003493836,0.00019768518,0.00035449272,0.00036580354,0.00022507428,0.00000549907,0.0001941429,0.00017404443,2.7080762e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011404933,0.00012188388,0.000073753596,0.000048606402,0.00013715572,0.000003296902,0.00171546,0.002103156,0.9900727,0.0013912987,0.0020148787,0.0011773086],"study_design_scores_gemma":[0.00581466,0.0007121604,0.00022110628,0.000092184826,0.0001290029,0.000052010084,0.0020742682,0.0032209908,0.95251095,0.000104999446,0.034686312,0.00038133163],"about_ca_topic_score_codex":0.0004661143,"about_ca_topic_score_gemma":0.00007199292,"teacher_disagreement_score":0.037561737,"about_ca_system_score_codex":0.00008951552,"about_ca_system_score_gemma":0.00014159875,"threshold_uncertainty_score":0.8061368},"labels":[],"label_agreement":null},{"id":"W4289597888","doi":"10.1016/j.bpj.2022.07.034","title":"Single-molecule counting applied to the study of GPCR oligomerization","year":2022,"lang":"en","type":"review","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"G protein-coupled receptor; Expansive; Computational biology; Function (biology); Photobleaching; Cell signaling; Receptor; Transmembrane protein; Biophysics; Biology; Signal transduction; Nanotechnology; Chemistry; Cell biology; Biochemistry; Physics; Materials science","score_opus":0.03455315879839811,"score_gpt":0.29014351950538586,"score_spread":0.25559036070698776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4289597888","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.031253353,0.9552363,0.007829057,0.000037484544,0.0017432228,0.0028284767,0.000061161794,0.000023199422,0.0009877472],"genre_scores_gemma":[0.033420745,0.96321833,0.00022432218,0.000119045755,0.0025453668,0.00013487361,0.0001310613,0.00011418524,0.00009206611],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99845,0.00018597014,0.0004970662,0.00028988742,0.00036824116,0.00020884864],"domain_scores_gemma":[0.99909776,0.000024698586,0.00045694967,0.0002864787,0.0000518273,0.00008226616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030169557,0.00024058475,0.0005899866,0.00006707709,0.00023541147,0.000067236426,0.00048228045,0.000099027355,0.000095990465],"category_scores_gemma":[0.00004296553,0.00016058628,0.00030408564,0.0002776367,0.000018563047,0.0000018459356,0.0002478475,0.00031767425,0.000007544844],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025374671,0.0005376361,3.2272624e-7,0.00029570685,0.00027926566,0.000005778541,0.00013771385,0.00008497981,0.49447194,0.00006641899,0.00024982519,0.50384504],"study_design_scores_gemma":[0.00017360064,0.00091245986,4.2318007e-7,0.00017169485,0.00026104256,0.000031817235,0.0002914796,0.000004643206,0.009414005,0.0000035929254,0.9885076,0.00022762196],"about_ca_topic_score_codex":0.0000034336133,"about_ca_topic_score_gemma":8.2078145e-7,"teacher_disagreement_score":0.98825777,"about_ca_system_score_codex":0.000033055843,"about_ca_system_score_gemma":0.00009674865,"threshold_uncertainty_score":0.65485185},"labels":[],"label_agreement":null},{"id":"W4290660012","doi":"10.1038/s41467-022-32386-x","title":"Allosteric modulation of GPCR-induced β-arrestin trafficking and signaling by a synthetic intrabody","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Daiichi Sankyo Europe; Moonshot Research and Development Program; Instituto de Salud Carlos III; Science and Engineering Research Board; Japan Society for the Promotion of Science; Wellcome Trust; Council of Scientific and Industrial Research, India; Department of Biotechnology, Ministry of Science and Technology, India; Ministerio de Economía y Competitividad; Indian Institute of Technology Kanpur; Government of Canada; The Wellcome Trust DBT India Alliance; Japan Science and Technology Agency; Daiichi Sankyo Foundation of Life Science; Canadian Institutes of Health Research; Uehara Memorial Foundation","keywords":"G protein-coupled receptor; Endosome; Arrestin; Phosphorylation; Allosteric regulation; Internalization; Cell biology; Effector; Biology; Receptor; Agonist; Signal transduction; Chemistry; Biochemistry","score_opus":0.013844612119075476,"score_gpt":0.2636719043591326,"score_spread":0.24982729224005715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4290660012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939556,0.0050932476,0.00033713708,0.00025634412,0.000056025612,0.00014159062,0.000018857922,0.0000071538966,0.00013405623],"genre_scores_gemma":[0.9977479,0.00014881276,0.0017564201,0.00007749213,0.000012721636,0.000038469094,0.00019504638,0.000012267081,0.000010866103],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993226,0.0001594855,0.00017745199,0.00015320687,0.00009380782,0.000093467075],"domain_scores_gemma":[0.9993701,0.00004308951,0.00008765792,0.0004405807,0.000034986435,0.000023595221],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026241015,0.00007173648,0.00009419326,0.000053617056,0.00015314334,0.000009709099,0.00031639234,0.00009757798,0.000021021679],"category_scores_gemma":[0.00005838042,0.000080279875,0.000027035148,0.00013323704,0.000026867248,0.0000033652007,0.00025401838,0.00031528398,1.5251497e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000132566,0.000057452762,0.0003331571,0.000004493586,0.0000094275365,1.5724133e-7,0.00013509468,0.00059639756,0.9957978,0.00039765038,0.000061153485,0.0025939592],"study_design_scores_gemma":[0.0016697444,0.00072813674,0.0038704118,0.00009569598,0.00006822211,0.000051540646,0.001971438,0.042803112,0.9220209,0.00075906224,0.025176458,0.0007852849],"about_ca_topic_score_codex":0.000019720324,"about_ca_topic_score_gemma":0.000027488435,"teacher_disagreement_score":0.07377691,"about_ca_system_score_codex":0.000014860042,"about_ca_system_score_gemma":0.000025448973,"threshold_uncertainty_score":0.32737184},"labels":[],"label_agreement":null},{"id":"W4291009261","doi":"10.1101/2022.08.08.502043","title":"Does phasic dopamine release cause policy updates?","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Langara College; Université de Montréal; Concordia University","funders":"","keywords":"Dopamine; Optogenetics; Dopaminergic; Stimulation; Neuroscience; Midbrain; Reinforcement learning; Biology; Psychology; Computer science; Artificial intelligence; Central nervous system","score_opus":0.009717872442518646,"score_gpt":0.23423744511450417,"score_spread":0.22451957267198552,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291009261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9927352,0.0015905913,0.0015273996,0.000373966,0.0021580006,0.0006746672,0.0007234832,0.00018999029,0.000026717902],"genre_scores_gemma":[0.99283487,0.0013372768,0.0022483116,0.0005726969,0.0023506545,0.00026946227,0.000012203035,0.00023183267,0.00014267575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9966017,0.00021104686,0.00057124725,0.0014527205,0.00042945638,0.0007338298],"domain_scores_gemma":[0.99706215,0.000017612483,0.00044306938,0.0018237425,0.00027772144,0.0003757011],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047791156,0.0007006422,0.00053879706,0.00027128978,0.00030203792,0.00019247046,0.0008849978,0.0005922846,0.0006716414],"category_scores_gemma":[0.00027749097,0.0006015601,0.00030041477,0.00036722494,0.00009842775,0.000010950481,0.001430507,0.00076296786,0.00003790198],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006674373,0.00014866762,0.000775784,0.00014485749,0.00024696245,0.00009564042,0.000003720442,0.00018072553,0.99698216,0.000621401,0.00072857615,0.0000047713884],"study_design_scores_gemma":[0.00056529103,0.00014117999,0.0012304703,0.000070090806,0.00010553656,4.3300076e-8,0.0000061826195,0.00007028452,0.89969856,0.0000063332445,0.09717696,0.00092906243],"about_ca_topic_score_codex":0.00014094672,"about_ca_topic_score_gemma":0.000005410626,"teacher_disagreement_score":0.09728359,"about_ca_system_score_codex":0.00016007875,"about_ca_system_score_gemma":0.00099706,"threshold_uncertainty_score":0.99964356},"labels":[],"label_agreement":null},{"id":"W4291582755","doi":"10.1097/j.pain.0000000000002751","title":"Distinct and sex-specific expression of mu opioid receptors in anterior cingulate and somatosensory S1 cortical areas","year":2022,"lang":"en","type":"article","venue":"Pain","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Neurological Disorders and Stroke; National Institute on Drug Abuse; Canadian Institutes of Health Research; Louise and Alan Edwards Foundation","keywords":"Somatosensory system; Neuroscience; Anterior cingulate cortex; Opioid; Psychology; Somatosensory evoked potential; Receptor; Cingulate cortex; Medicine; Internal medicine; Central nervous system; Cognition","score_opus":0.007958223866944314,"score_gpt":0.21667607745460865,"score_spread":0.20871785358766434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291582755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99741083,0.0010070596,0.0013315127,0.000013435152,0.00008577776,0.00009160154,0.000010428085,0.0000044682083,0.000044884673],"genre_scores_gemma":[0.99924153,0.00014643311,0.0004003337,0.000030058389,0.00004348193,0.000013222469,0.000030417457,0.000012186949,0.00008234311],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99903333,0.00032463713,0.00018583285,0.00023352673,0.000085023865,0.00013763625],"domain_scores_gemma":[0.9997287,0.000044157383,0.000053840078,0.000114042356,0.000008541491,0.000050743958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007280334,0.000086458174,0.00014015938,0.000035281897,0.00008805003,0.000008420456,0.0000531118,0.000046808484,0.00012926734],"category_scores_gemma":[0.00006792844,0.000082704035,0.0000275323,0.00003812877,0.000047690293,0.0000018124261,0.00014650352,0.00008166497,3.1486718e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005398427,0.000028988527,0.029136378,0.000023417284,0.0000038103992,0.000004409876,0.00028934583,0.000006683996,0.9611327,0.000018195848,0.00008536743,0.009216723],"study_design_scores_gemma":[0.00061191875,0.00033186786,0.006988552,0.00006464594,0.000004594909,0.000021172975,0.001424005,0.0007168768,0.9790256,0.00017465262,0.010422202,0.00021392267],"about_ca_topic_score_codex":0.000018852625,"about_ca_topic_score_gemma":0.0000065516188,"teacher_disagreement_score":0.022147827,"about_ca_system_score_codex":0.000010757554,"about_ca_system_score_gemma":0.000016110695,"threshold_uncertainty_score":0.33725727},"labels":[],"label_agreement":null},{"id":"W4292079763","doi":"10.1021/acsbiomedchemau.2c00047","title":"Shedding Light on the Elephant in a Dark Room in the Discovery of New Medicine: Highlighting Molecular Pharmaceutics within <i>ACS Bio &amp; Med Chem Au</i>","year":2022,"lang":"en","type":"editorial","venue":"ACS Bio & Med Chem Au","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Pharmacy; Citation; Library science; Medicine; Computer science; Family medicine","score_opus":0.014303487156837323,"score_gpt":0.27966725520297686,"score_spread":0.26536376804613954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292079763","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8178174,0.0046502193,0.0003926007,0.004473291,0.16951258,0.0014619505,0.000156243,0.000038678707,0.0014970279],"genre_scores_gemma":[0.79911166,0.0022493277,0.00024692135,0.0013267394,0.19278522,0.00025739873,0.002386261,0.00026167708,0.0013747838],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9950371,0.00044513354,0.0011566461,0.0010442463,0.0014716818,0.00084521633],"domain_scores_gemma":[0.9973111,0.0004830561,0.00082356756,0.0011236161,0.00011509485,0.00014356915],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0029446203,0.000766996,0.0008739103,0.00020445415,0.00021545235,0.00008202185,0.001714631,0.00091081567,0.000060736867],"category_scores_gemma":[0.00149475,0.0004936978,0.00027218275,0.0006754586,0.00014036839,0.000015991784,0.0005138786,0.0015350076,0.0000033798985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021527137,0.000107291264,0.000029340354,0.000107531014,0.00016878368,0.00003292576,0.0025257037,0.00008953504,0.84084874,0.00013708942,0.15556018,0.00017760247],"study_design_scores_gemma":[0.0010631592,0.00018349194,0.0000018567696,0.00032778096,0.0001199209,0.000004521917,0.00088476826,0.000010389202,0.6892688,0.00016090804,0.30757064,0.00040372234],"about_ca_topic_score_codex":0.0006007192,"about_ca_topic_score_gemma":0.00047225427,"teacher_disagreement_score":0.15201046,"about_ca_system_score_codex":0.0003376365,"about_ca_system_score_gemma":0.001245515,"threshold_uncertainty_score":0.99975145},"labels":[],"label_agreement":null},{"id":"W4292951000","doi":"10.3407/rpn.v5i2.6883","title":"Extractos de plantas de la región Caribe colombiana contra larvas del mosquito vector del dengue, zika y chikungunya.","year":2022,"lang":"es","type":"article","venue":"Revista Productos Naturales","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS)","keywords":"Chikungunya; Dengue fever; Zika virus; Vector (molecular biology); Biology; Virology; Aedes aegypti; Aedes; Yellow fever; Humanities; Virus; Larva; Philosophy","score_opus":0.006053348524876011,"score_gpt":0.24977136175618317,"score_spread":0.24371801323130715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4292951000","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88294816,0.11374284,0.00016535218,0.00061482657,0.0005701874,0.000974777,0.00062475516,0.00006897759,0.0002901514],"genre_scores_gemma":[0.98722017,0.00657888,0.0013171241,0.00058519474,0.0015803684,0.00016194447,0.0009094951,0.00014468037,0.0015021536],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950679,0.0012508045,0.0006996727,0.0013417325,0.00052640017,0.0011134907],"domain_scores_gemma":[0.9978136,0.00018668827,0.00046031125,0.0010097536,0.00019279381,0.00033687952],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001670175,0.0006690283,0.0007601629,0.00013313172,0.00079175836,0.0004176822,0.0009644683,0.0005356628,0.00032688756],"category_scores_gemma":[0.0008023892,0.0006912932,0.00042697816,0.0003250106,0.00022618922,0.000025661124,0.00050318846,0.0012630443,0.000012778538],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003668475,0.00027636075,0.003758852,0.0005176172,0.00047129788,0.00019487471,0.000287266,0.00022380531,0.97081673,0.007916455,0.012537467,0.0026324424],"study_design_scores_gemma":[0.0012953873,0.0005493479,0.0039718356,0.0002445208,0.00046275818,0.0010534558,0.0005792147,0.0002907658,0.45578825,0.0001946431,0.5342911,0.0012787652],"about_ca_topic_score_codex":0.00014098431,"about_ca_topic_score_gemma":0.00001371951,"teacher_disagreement_score":0.5217536,"about_ca_system_score_codex":0.0003498266,"about_ca_system_score_gemma":0.0009482248,"threshold_uncertainty_score":0.9995538},"labels":[],"label_agreement":null},{"id":"W4293051400","doi":"10.1016/j.jbc.2022.102421","title":"G protein–coupled receptor kinase 6 (GRK6) regulates insulin processing and secretion via effects on proinsulin conversion to insulin","year":2022,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"Proinsulin; Insulin; Insulin receptor; Insulin receptor substrate; Internal medicine; Endocrinology; Secretion; Receptor; Chemistry; Protein kinase A; Kinase; Cell biology; Biology; Medicine; Insulin resistance; Biochemistry","score_opus":0.008525693016152558,"score_gpt":0.2211763887732692,"score_spread":0.21265069575711665,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293051400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996898,0.0011873246,0.0010975099,0.00037991992,0.00010940289,0.00027695484,0.000014256918,0.000011844723,0.000024778925],"genre_scores_gemma":[0.9968855,0.00009675988,0.0020132943,0.00028989447,0.0005014905,0.000032775257,0.00008745821,0.000018110466,0.00007474914],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99860036,0.0001428609,0.0004017026,0.00037147856,0.00026259213,0.00022102785],"domain_scores_gemma":[0.99912333,0.000038993505,0.00035877657,0.00014592192,0.00013037352,0.00020261425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005803473,0.00021110833,0.00028674983,0.000036930924,0.00019606514,0.000032969314,0.00022389095,0.00021241145,0.00021997302],"category_scores_gemma":[0.00033145602,0.00016494689,0.000112653346,0.00013154947,0.000043169286,0.0000070811684,0.0002096895,0.0003694278,0.0000030152332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013864813,0.00012342162,0.00011100971,0.00006429179,0.000026054513,0.00001837801,0.000041148556,0.0000831979,0.9858418,0.0000020658679,0.000095064854,0.0122071],"study_design_scores_gemma":[0.001004579,0.0019927453,0.00018414165,0.00010569268,0.000012506729,0.000045086228,0.00010753256,0.0003221003,0.9917077,0.00022955558,0.0040646396,0.00022376477],"about_ca_topic_score_codex":0.000003876179,"about_ca_topic_score_gemma":9.6355755e-8,"teacher_disagreement_score":0.011983335,"about_ca_system_score_codex":0.00006388467,"about_ca_system_score_gemma":0.000074163574,"threshold_uncertainty_score":0.6726339},"labels":[],"label_agreement":null},{"id":"W4293223886","doi":"10.1111/adb.13227","title":"The GPR88 agonist RTI‐13951‐33 reduces alcohol drinking and seeking in mice","year":2022,"lang":"en","type":"article","venue":"Addiction Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institute on Alcohol Abuse and Alcoholism; Korea National Institute of Health; National Institutes of Health; Canada Research Chairs","keywords":"Knockout mouse; Conditioned place preference; Self-administration; Pharmacology; Alcohol; Psychology; Addiction; Agonist; In vivo; Medicine; Neuroscience; Receptor; Chemistry; Internal medicine; Biology; Biochemistry","score_opus":0.009984675769229725,"score_gpt":0.24724664876509264,"score_spread":0.2372619729958629,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293223886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948061,0.0026671067,0.00048227984,0.0003963041,0.0006638102,0.0001302851,0.000012439866,0.000015703637,0.0008259638],"genre_scores_gemma":[0.99831086,0.00060011464,0.00014155917,0.00027373838,0.00018707808,0.00006989973,0.00013196726,0.00001245812,0.00027233287],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99904335,0.00018070724,0.00018980482,0.00030174782,0.000057878082,0.00022652408],"domain_scores_gemma":[0.99970454,0.00003148924,0.00008765342,0.00012480472,0.00002032156,0.00003120073],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004320491,0.00009905017,0.00009591349,0.000044113323,0.000569602,0.000027352738,0.00014407307,0.00008545304,0.00009432396],"category_scores_gemma":[0.000040135612,0.00008273173,0.00004088084,0.00010321239,0.00007366366,0.0000029893329,0.00020174393,0.00016394642,0.0000016447111],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050188723,0.000013096337,0.0017751127,8.089677e-7,0.000026345351,0.0000014713622,0.00008448785,0.00007307108,0.98268265,0.0008071675,0.00041508075,0.014070553],"study_design_scores_gemma":[0.0007499867,0.0005608355,0.0015041833,0.000009384137,0.0000183458,0.00010123132,0.0012357859,0.000813021,0.34338757,0.0013452304,0.64997524,0.00029918138],"about_ca_topic_score_codex":0.000070468,"about_ca_topic_score_gemma":0.00008832951,"teacher_disagreement_score":0.64956015,"about_ca_system_score_codex":0.00002326924,"about_ca_system_score_gemma":0.000031247975,"threshold_uncertainty_score":0.43809757},"labels":[],"label_agreement":null},{"id":"W4294073980","doi":"10.1038/s41398-022-02136-0","title":"Microstructural imaging and transcriptomics of the basal forebrain in first-episode psychosis","year":2022,"lang":"en","type":"article","venue":"Translational Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Douglas Mental Health University Institute; McGill University; Douglas College; Dalhousie University; University of Toronto; Lawson Health Research Institute; Western University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; University of Toronto; Government of Canada; Canada First Research Excellence Fund; Government of Ontario; Compute Canada; Academic Medical Organization of Southwestern Ontario; McGill University; Chrysalis","keywords":"Psychosis; Basal forebrain; Nucleus basalis; Myelin; Cholinergic; Neuroscience; Psychology; Schizophrenia (object-oriented programming); Cholinergic neuron; Internal medicine; Medicine; Psychiatry; Central nervous system","score_opus":0.005286100246009142,"score_gpt":0.21685752362556077,"score_spread":0.21157142337955162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294073980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99297816,0.0015334022,0.0013198175,0.0032462145,0.0005598636,0.0001506261,0.000092847986,0.000002901921,0.00011619324],"genre_scores_gemma":[0.99637574,0.00001595858,0.0029615862,0.0004877423,0.000067748944,0.000015060783,0.000040795752,0.000012698951,0.000022696366],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9993425,0.000043409946,0.00019160949,0.00018407655,0.00012320396,0.000115192284],"domain_scores_gemma":[0.9998008,0.000007082593,0.00004752445,0.000112469614,0.000011748444,0.000020401072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013322127,0.0000856462,0.0000804261,0.000033189273,0.00013618977,0.0000067756514,0.00013860397,0.00003112713,0.00010809315],"category_scores_gemma":[0.000002239996,0.00007568394,0.0000886455,0.00009151892,0.0000430212,0.0000039093716,0.000020565893,0.00010780996,1.0022502e-7],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022794136,0.000065522545,0.5537491,0.000041646843,0.000033001226,1.6970571e-7,0.0003932515,0.0027515409,0.4367876,0.0035881437,0.0011225153,0.0012395908],"study_design_scores_gemma":[0.009605956,0.0004168376,0.7227084,0.00010902985,0.000102120954,0.000116859585,0.0018585407,0.01357971,0.127378,0.09001201,0.03284789,0.0012646704],"about_ca_topic_score_codex":0.000052894622,"about_ca_topic_score_gemma":0.00039400224,"teacher_disagreement_score":0.30940962,"about_ca_system_score_codex":0.000004961278,"about_ca_system_score_gemma":0.000025779991,"threshold_uncertainty_score":0.30863014},"labels":[],"label_agreement":null},{"id":"W4294666970","doi":"10.1021/acs.jmedchem.2c00786","title":"From a Cone Snail Toxin to a Competitive MC4R Antagonist","year":2022,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"FP7 Health; Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Université de Paris; Canada Research Chairs","keywords":"Chemistry; Melanocortin 4 receptor; Antagonist; Energy homeostasis; Peptide; Conotoxin; Venom; Melanocortin; Endogeny; Receptor; Competitive antagonist; Pharmacology; Biochemistry; Biology","score_opus":0.0076959890310284934,"score_gpt":0.24313449297126283,"score_spread":0.23543850394023433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294666970","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99411625,0.0011342351,0.0015363444,0.0009541441,0.00042017546,0.000057290716,0.00006530456,0.0000036788501,0.0017125551],"genre_scores_gemma":[0.9955545,0.000045610068,0.0010532137,0.0009113147,0.0017034317,0.000006574703,0.00005668545,0.000017880306,0.00065077265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987369,0.000050532737,0.00037192754,0.0001948915,0.00045870116,0.00018700963],"domain_scores_gemma":[0.99919206,0.000024610914,0.00026200194,0.00016433363,0.00013253833,0.00022444194],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004235801,0.00013469471,0.00025683045,0.00002697309,0.00012404288,0.0000162888,0.0003254504,0.00006497476,0.0022075258],"category_scores_gemma":[0.00011097349,0.00012449273,0.00013492204,0.00008459346,0.000041708812,0.0000028626662,0.00016428748,0.00033402862,0.0000030509434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042176578,0.000072385905,0.00009541035,0.000011136141,0.000084160376,0.000116246345,0.00021825392,0.00007736732,0.99032164,0.0000103358125,0.007930753,0.000640564],"study_design_scores_gemma":[0.0009849648,0.0006206293,0.00004110425,0.000043690397,0.0000374733,0.00040507063,0.003949645,0.000012008389,0.8856996,0.00008856095,0.10797642,0.00014081762],"about_ca_topic_score_codex":0.000017386534,"about_ca_topic_score_gemma":0.0000012445837,"teacher_disagreement_score":0.10462201,"about_ca_system_score_codex":0.00006215186,"about_ca_system_score_gemma":0.00019118645,"threshold_uncertainty_score":0.9987046},"labels":[],"label_agreement":null},{"id":"W4294953656","doi":"10.3410/f.742302040.793595203","title":"Faculty Opinions recommendation of A locus coeruleus-dorsal CA1 dopaminergic circuit modulates memory linking.","year":2022,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Locus coeruleus; Dopaminergic; Dorsum; Neuroscience; Psychology; Biology; Anatomy; Dopamine; Central nervous system","score_opus":0.023018623862813524,"score_gpt":0.3100155500008795,"score_spread":0.286996926138066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4294953656","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000010606199,0.0038474477,0.00011828087,0.022945324,0.0013852197,0.0010301047,0.97058934,0.000022381202,0.000051312043],"genre_scores_gemma":[0.00009488886,0.00075201975,0.0002489021,0.0023915467,0.0004187338,0.0002618809,0.99459815,0.000045355642,0.0011885165],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9954626,0.00053230184,0.0014813339,0.00087246124,0.0012508144,0.0004004734],"domain_scores_gemma":[0.9937821,0.000059085298,0.0015030779,0.0014910458,0.0029471358,0.0002175501],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014380183,0.00057250226,0.00086565764,0.00026719598,0.000312692,0.00010054149,0.0017273856,0.0007979556,0.0034432632],"category_scores_gemma":[0.0023788582,0.00041413744,0.000784346,0.0011201788,0.00023303082,0.000032310843,0.000862549,0.00095099123,0.000011820523],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018097633,0.00026855583,0.0000015150334,0.0031132216,0.00020483676,4.6260192e-7,0.000056211677,0.0000033061835,0.00045472776,0.00009888065,0.99382734,0.0019528352],"study_design_scores_gemma":[0.00060918124,0.0002631128,0.000044423003,0.0024996626,0.00016811334,0.000048128968,0.00004279517,0.00001326159,0.0010069289,0.000033883964,0.9948477,0.0004228022],"about_ca_topic_score_codex":0.000073790296,"about_ca_topic_score_gemma":0.0000049268724,"teacher_disagreement_score":0.024008833,"about_ca_system_score_codex":0.000083863495,"about_ca_system_score_gemma":0.0005426726,"threshold_uncertainty_score":0.999831},"labels":[],"label_agreement":null},{"id":"W4295754160","doi":"10.1002/prp2.1003","title":"The signaling and selectivity of α‐adrenoceptor agonists for the human <scp>α2A</scp>, <scp>α2B</scp> and <scp>α2C</scp>‐adrenoceptors and comparison with human α1 and β‐adrenoceptors","year":2022,"lang":"en","type":"article","venue":"Pharmacology Research & Perspectives","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Graduate Education; Medical Research Council; Medical Research Council Canada; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Adrenergic receptor; Agonist; Receptor; Pharmacology; Medicine; Internal medicine","score_opus":0.035670028496345305,"score_gpt":0.3604418743473887,"score_spread":0.3247718458510434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4295754160","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9727143,0.024530953,0.00029017893,0.00023171681,0.0001679574,0.0016015504,0.000097091506,0.00003730471,0.00032894604],"genre_scores_gemma":[0.9952181,0.002026455,0.00025949604,0.000070803435,0.0004894903,0.0005537589,0.000046424302,0.00009896091,0.0012365152],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9951656,0.001167754,0.0004963603,0.0013074451,0.0006601787,0.0012026632],"domain_scores_gemma":[0.9950104,0.0033460248,0.00035620376,0.00036070644,0.00056976086,0.00035690647],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0032968558,0.0005297637,0.0006516481,0.00026203773,0.00520147,0.00027977378,0.00060562487,0.00023692349,0.000049231454],"category_scores_gemma":[0.0007195737,0.00039592822,0.00013238988,0.00043597075,0.0026134471,0.000044644967,0.0010093931,0.0011640424,6.42461e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008104819,0.00027310802,0.012797483,0.0001079626,0.00081588776,0.0000049381633,0.011168322,0.000090868554,0.96306574,0.001005603,0.009874849,0.0007142094],"study_design_scores_gemma":[0.0034340245,0.0047283107,0.0073337904,0.000029255098,0.00029887294,0.00009766472,0.09505651,0.00059902866,0.8550313,0.0012329156,0.03197853,0.00017979719],"about_ca_topic_score_codex":0.00018236498,"about_ca_topic_score_gemma":0.00012480338,"teacher_disagreement_score":0.108034424,"about_ca_system_score_codex":0.00010803736,"about_ca_system_score_gemma":0.00022201259,"threshold_uncertainty_score":0.99984926},"labels":[],"label_agreement":null},{"id":"W4296008621","doi":"10.1177/02698811221122019","title":"Cell-based serum anticholinergic activity assay and working memory in cognitively healthy older adults before and after scopolamine: An exploratory study","year":2022,"lang":"en","type":"article","venue":"Journal of Psychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Ottawa; Centre for Addiction and Mental Health","funders":"Centre for Addiction and Mental Health Foundation","keywords":"Anticholinergic; Working memory; Muscarinic acetylcholine receptor; Cognition; Psychology; Scopolamine; Cambridge Neuropsychological Test Automated Battery; Executive functions; Neuropsychology; Medicine; Anesthesia; Internal medicine; Neuroscience; Receptor; Spatial memory","score_opus":0.009140492486558599,"score_gpt":0.29039002401364333,"score_spread":0.28124953152708476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4296008621","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99708027,0.0015562305,0.00018317928,0.0001660936,0.0006735268,0.0003182664,0.000009946136,0.000003343083,0.000009154166],"genre_scores_gemma":[0.9982655,0.00011067761,0.00021038581,0.0009964937,0.00033334605,0.00004285193,0.0000033301656,0.00002540257,0.000012019123],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.998197,0.0007252076,0.00034007843,0.000316094,0.00017671748,0.00024490847],"domain_scores_gemma":[0.99934417,0.000030418665,0.0002923388,0.00009331944,0.00008326406,0.0001564928],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011304895,0.0001673335,0.00027211424,0.00019352352,0.00012258069,0.000018180202,0.00012287353,0.00008441381,0.0001313973],"category_scores_gemma":[0.000010391001,0.00016174479,0.00005067038,0.00012244681,0.000046878475,0.000017000506,0.00009247659,0.00043492788,2.2355734e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.019663915,0.004286805,0.14355564,0.00012247445,0.00017031535,0.0006128029,0.0047221435,0.0004660786,0.80717814,7.229662e-7,0.0004582477,0.018762749],"study_design_scores_gemma":[0.093878254,0.046345763,0.5811386,0.00025752932,0.0004780395,0.0006060958,0.035211906,0.003069637,0.23565072,0.00009417364,0.0015988321,0.0016704308],"about_ca_topic_score_codex":0.000005570544,"about_ca_topic_score_gemma":0.000051377912,"teacher_disagreement_score":0.57152736,"about_ca_system_score_codex":0.00002894503,"about_ca_system_score_gemma":0.00012066007,"threshold_uncertainty_score":0.65957606},"labels":[],"label_agreement":null},{"id":"W4297021384","doi":"10.1093/plcell/koac295","title":"CNGCs as stomatal gatekeepers during ABA signaling","year":2022,"lang":"en","type":"letter","venue":"The Plant Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Biology; Cell biology; Botany","score_opus":0.00921468648623557,"score_gpt":0.19140258874127872,"score_spread":0.18218790225504314,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297021384","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96676314,0.0024906327,0.000094829644,0.020906888,0.0017165025,0.0005863194,0.00090020633,0.0000817978,0.006459701],"genre_scores_gemma":[0.41733763,0.0017922891,0.0005596349,0.45292836,0.020101497,0.00031268303,0.024174694,0.0006848494,0.08210835],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9982551,0.00012900883,0.00025461242,0.0005078336,0.0003664662,0.00048700688],"domain_scores_gemma":[0.9991984,0.0000389869,0.00018295844,0.00050614885,0.000022362046,0.000051187977],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023908187,0.00034296722,0.00024891744,0.000056841436,0.00037903237,0.00006572232,0.0006457959,0.00042119532,0.0020183325],"category_scores_gemma":[0.000011515371,0.00027201802,0.0002886388,0.00005797216,0.000041798336,0.0000022287288,0.00031385344,0.0010376341,0.00009294027],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006025012,0.000011536573,0.000002112509,0.0000775712,0.000091117385,0.00026201052,0.00011480227,0.00028499812,0.7639049,0.0000041099393,0.23515998,0.000026579482],"study_design_scores_gemma":[0.00018244039,0.00011144027,5.652642e-7,0.00001764902,0.000052821197,0.00015442746,0.00014132712,0.00001697649,0.47108766,0.000025461599,0.5279035,0.00030573126],"about_ca_topic_score_codex":0.000067366236,"about_ca_topic_score_gemma":0.000002388998,"teacher_disagreement_score":0.5494255,"about_ca_system_score_codex":0.00003234765,"about_ca_system_score_gemma":0.00008273582,"threshold_uncertainty_score":0.9999732},"labels":[],"label_agreement":null},{"id":"W4297789999","doi":"10.1101/2022.08.31.506132","title":"Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"National Health and Medical Research Council; National Cancer Institute; Medical Research Council; Australian Government; National Computational Infrastructure","keywords":"Allosteric regulation; Cholesterol; Biochemistry; Chemistry; Transporter; Neurotransmitter transporter; Glycine receptor; Glycine; Biophysics; Biology; Enzyme; Amino acid","score_opus":0.007821583465192152,"score_gpt":0.19703802541848525,"score_spread":0.1892164419532931,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297789999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99434096,0.0025628272,0.0010190733,0.00029767957,0.0004861582,0.00066103786,0.0005444406,0.000080338315,0.0000074873114],"genre_scores_gemma":[0.99726856,0.0013922874,0.0003184775,0.000322309,0.00032817913,0.00018059874,0.000026385482,0.00012704643,0.000036153706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975193,0.00012649625,0.0005270411,0.0010497186,0.00033282387,0.00044460237],"domain_scores_gemma":[0.9984909,0.000012049877,0.00029798623,0.00088622095,0.0001288034,0.0001839905],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005614786,0.00054590247,0.0004278759,0.00007498452,0.0002928895,0.000104875435,0.00037054764,0.00048182582,0.00017631937],"category_scores_gemma":[0.00001251052,0.00048981747,0.00018721701,0.00016508202,0.00014025262,0.00001320681,0.00014568811,0.0006037441,0.0000024319006],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008890382,0.00007085433,0.0011935538,0.0001627991,0.00013545253,0.00001621209,0.000014180538,0.000101072066,0.997977,0.000069212285,0.00016758268,0.0000031534476],"study_design_scores_gemma":[0.00074834406,0.00014258613,0.011062395,0.0000942067,0.00013540487,1.454962e-7,0.000010324088,0.000047837966,0.97786075,0.0000023286796,0.009317489,0.00057821826],"about_ca_topic_score_codex":0.00006861261,"about_ca_topic_score_gemma":0.000010400868,"teacher_disagreement_score":0.020116303,"about_ca_system_score_codex":0.000033780332,"about_ca_system_score_gemma":0.00016507105,"threshold_uncertainty_score":0.9997553},"labels":[],"label_agreement":null},{"id":"W4297825842","doi":"10.1101/2022.09.06.506781","title":"Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Faculty of Medicine, McGill University; McGill University","keywords":"Transcriptome; Biology; Cell biology; MAPK/ERK pathway; Kinase; Computational biology; Myocyte; Signal transduction; Cell; In vivo; In vitro; Neuroscience; Gene expression; Genetics; Gene","score_opus":0.012639637279204412,"score_gpt":0.21259272451927338,"score_spread":0.19995308724006897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297825842","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867666,0.011396905,0.00079090043,0.00002851668,0.00034957015,0.000536825,0.0000772635,0.00004560039,0.000007829382],"genre_scores_gemma":[0.9971098,0.00057412527,0.0017824935,0.000059269594,0.0002837899,0.00009794058,0.0000053243803,0.00008411463,0.0000031874924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979102,0.0001980101,0.00046277166,0.0007923341,0.0002868499,0.00034982388],"domain_scores_gemma":[0.99880844,0.000034149176,0.00030776806,0.00057987124,0.00014752899,0.00012226294],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006923256,0.00042468536,0.0005908547,0.00010772625,0.0003757308,0.00013439727,0.00039090714,0.00027963362,0.00002198168],"category_scores_gemma":[0.000035110366,0.00038627628,0.00015904268,0.00012168029,0.00014352727,0.00001178759,0.0007498518,0.00050716056,2.6490528e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051042858,0.000021766778,0.0093826605,0.00042212196,0.00020959199,0.000007500486,0.000042289947,0.00023972012,0.9894369,0.00017387167,0.000009688925,0.000002820305],"study_design_scores_gemma":[0.0005534298,0.00011769671,0.005653622,0.00012907613,0.00013569389,1.304594e-7,0.00006203448,0.00020060342,0.9919821,0.0000031146335,0.0006981934,0.00046432414],"about_ca_topic_score_codex":0.000036411253,"about_ca_topic_score_gemma":0.0000027808528,"teacher_disagreement_score":0.0108227795,"about_ca_system_score_codex":0.000029934607,"about_ca_system_score_gemma":0.0001693664,"threshold_uncertainty_score":0.9998589},"labels":[],"label_agreement":null},{"id":"W4297995910","doi":"10.1126/science.abn7065","title":"Structure-based discovery of nonopioid analgesics acting through the α <sub>2A</sub> -adrenergic receptor","year":2022,"lang":"en","type":"article","venue":"Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute of Mental Health; Canadian Institutes of Health Research; Defense Advanced Research Projects Agency; National Science Foundation; National Institutes of Health; Science, Technology and Innovation Commission of Shenzhen Municipality; Deutsche Forschungsgemeinschaft; Open Philanthropy Project","keywords":"Adrenergic; Virtual screening; Chemistry; Adrenergic receptor; Pharmacology; Receptor; Computational biology; Bioinformatics; Medicine; Drug discovery; Biology; Biochemistry","score_opus":0.008896766678644474,"score_gpt":0.23168585825522703,"score_spread":0.22278909157658255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297995910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9930092,0.0002790726,0.005735297,0.000102717444,0.0005268305,0.00010438226,0.00004361502,0.000006204768,0.00019269469],"genre_scores_gemma":[0.9984898,0.000022243625,0.0009934225,0.00028908756,0.00011186266,0.000011251472,0.00002733092,0.000010640311,0.000044372493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99873704,0.000065865126,0.00017221853,0.0003578177,0.00040650106,0.000260579],"domain_scores_gemma":[0.9993604,0.000020870719,0.00015400212,0.00036629033,0.000064368454,0.000034102926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044265515,0.000108762506,0.00010259707,0.000034020413,0.00057494367,0.000054013235,0.0006105778,0.00003316947,0.00006838234],"category_scores_gemma":[0.00007478715,0.000081010134,0.00007690132,0.0004504159,0.00027180096,0.000016357913,0.00027717798,0.00012638343,7.33129e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027425749,0.000014333346,0.00009054647,0.0000048486863,0.000005284748,3.5160613e-7,0.00009429052,0.0074382247,0.9901859,0.00039145048,0.000067388966,0.001679952],"study_design_scores_gemma":[0.00013165618,0.00020569008,0.0000755863,0.0000048876486,0.0000062192426,0.000002375031,0.00044092428,0.00041510173,0.9958586,0.00032848417,0.0024177735,0.00011270087],"about_ca_topic_score_codex":0.00001888434,"about_ca_topic_score_gemma":0.000007077422,"teacher_disagreement_score":0.0070231226,"about_ca_system_score_codex":0.000030410398,"about_ca_system_score_gemma":0.00033680483,"threshold_uncertainty_score":0.44220603},"labels":[],"label_agreement":null},{"id":"W4298219754","doi":"10.48550/arxiv.1510.00455","title":"Semidefinite relaxations in optimal experiment design with application\\n to substrate injection for hyperpolarized MRI","year":2015,"lang":"en","type":"preprint","venue":"arXiv (Cornell University)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Mathematical optimization; Relaxation (psychology); Maximization; Norm (philosophy); Quadratic equation; Mathematics; Computer science; Applied mathematics","score_opus":0.05988242070470816,"score_gpt":0.212651249832387,"score_spread":0.15276882912767886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4298219754","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.35939094,0.000047634505,0.63962233,0.000017426868,0.000065055465,0.0006995045,0.000024004383,0.000015663707,0.00011741515],"genre_scores_gemma":[0.9768128,0.000038815822,0.0221656,0.00003920244,0.000073579875,0.000052755786,0.00028009978,0.00003106383,0.0005060946],"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988091,0.000072623974,0.00016326581,0.0006933157,0.000049859522,0.00021185595],"domain_scores_gemma":[0.9991047,0.000018176228,0.0001467032,0.00040338354,0.0002037785,0.00012329803],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029480454,0.00021274554,0.00019522334,0.00012821465,0.00007833501,0.000032052496,0.00023591005,0.00029099584,0.000007455514],"category_scores_gemma":[0.000021641268,0.00023341387,0.00007692724,0.00018589107,0.0000270601,0.000007100899,0.00016126253,0.00016022538,0.0000070352503],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006114444,0.0000650861,0.00024178966,0.000015272175,0.000054429,0.0000037292152,0.00013602976,0.8966919,0.100201376,0.0017791387,0.00014482968,0.000054949433],"study_design_scores_gemma":[0.0066352454,0.0039442102,0.00025706307,0.00025006905,0.00033467126,0.00001983826,0.0023534156,0.3952664,0.57023793,0.009847483,0.00838297,0.0024706835],"about_ca_topic_score_codex":0.00008056215,"about_ca_topic_score_gemma":0.00005865325,"teacher_disagreement_score":0.61745673,"about_ca_system_score_codex":0.00012174991,"about_ca_system_score_gemma":0.00023401126,"threshold_uncertainty_score":0.95183414},"labels":[],"label_agreement":null},{"id":"W4301361266","doi":"10.17615/vfjm-vw90","title":"Dynamic Regulation of Mammalian Numb by G Protein-coupled Receptors and Protein Kinase C Activation: Structural Determinants of Numb Association with the Cortical Membrane","year":2020,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; National Institutes of Health; Hospital for Sick Children","keywords":"NUMB; Cell biology; Receptor; Association (psychology); Kinase; Chemistry; Biology; Neuroscience; Biochemistry; Psychology","score_opus":0.005596737224400561,"score_gpt":0.19797408079464832,"score_spread":0.19237734357024774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4301361266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99726385,0.000059645256,0.0015076468,0.0006740495,0.000020824395,0.00042620953,0.000015447482,0.000008345961,0.000023966299],"genre_scores_gemma":[0.99638087,0.0000016222202,0.003099495,0.000041554198,0.00003731913,0.000011892959,0.00008265514,0.000015190861,0.00032942183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923676,0.00007167814,0.00020670069,0.00018706423,0.00018181467,0.00011596991],"domain_scores_gemma":[0.9995273,0.000017117869,0.00022986977,0.00011072829,0.00007094623,0.00004405971],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009376576,0.00011255755,0.00016013463,0.000014730474,0.00008093558,0.00003349337,0.0000900137,0.00011761198,0.000074797834],"category_scores_gemma":[0.00011656675,0.00007814125,0.000031746127,0.00011088451,0.00008547581,0.000028278879,0.00004194466,0.000073869734,2.7072238e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031348356,0.000008471883,0.0019301435,0.00006733284,0.000029016439,1.834433e-7,0.00021952343,0.000019376044,0.99557155,0.001488789,0.000059020702,0.00029308215],"study_design_scores_gemma":[0.00039560333,0.00036433837,0.0010758814,0.00003218747,0.000015130195,6.8363175e-7,0.00020623415,0.0018113487,0.9953603,0.00045208214,0.0001860021,0.00010022207],"about_ca_topic_score_codex":0.000016486389,"about_ca_topic_score_gemma":0.000006480836,"teacher_disagreement_score":0.0017919727,"about_ca_system_score_codex":0.000008713907,"about_ca_system_score_gemma":0.00005495552,"threshold_uncertainty_score":0.31865078},"labels":[],"label_agreement":null},{"id":"W4302023489","doi":"10.21203/rs.3.rs-2121929/v1","title":"Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Université de Montréal; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Fondation Brain Canada; McGill University","keywords":"Memory consolidation; Neuroscience; Excitatory postsynaptic potential; Long-term potentiation; Fear conditioning; Conditional gene knockout; Knockout mouse; Inhibitory postsynaptic potential; Working memory; Glutamatergic; Hippocampus; Biology; Psychology; Glutamate receptor; Cognition; Amygdala; Genetics; Gene; Phenotype","score_opus":0.041081066435489554,"score_gpt":0.3167261342657269,"score_spread":0.27564506783023734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4302023489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96176237,0.017072974,0.014200448,0.000463111,0.000600737,0.0028731609,0.00048354166,0.000019465375,0.0025241803],"genre_scores_gemma":[0.9959869,0.00031334048,0.00023021185,0.0000110162,0.00049625407,0.00028732998,0.00088945124,0.000051729585,0.0017338142],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99675053,0.00077775354,0.00036487624,0.00059209066,0.0010562851,0.00045845742],"domain_scores_gemma":[0.9988052,0.000098117554,0.00016227532,0.00057180936,0.00027484956,0.00008774153],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0020269835,0.00022013455,0.0002643527,0.0001139138,0.0003931981,0.00007700563,0.0006715922,0.00031594577,0.0016507801],"category_scores_gemma":[0.00006848346,0.0001846707,0.00022524701,0.0001565622,0.00012928263,0.00000223821,0.00046915555,0.001162459,0.0000061100936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027356358,0.00007477743,0.00016454651,0.00016656125,0.00006801207,0.000004278929,0.00018262498,0.0015218175,0.99255115,0.00011611812,0.0020009163,0.0028756165],"study_design_scores_gemma":[0.0009291469,0.0004345512,0.000044841785,0.00020003265,0.000016008054,0.00000245231,0.0009214633,0.0006344548,0.9429724,0.0003711538,0.053131778,0.00034172044],"about_ca_topic_score_codex":0.00016975935,"about_ca_topic_score_gemma":0.000013695447,"teacher_disagreement_score":0.05113086,"about_ca_system_score_codex":0.00005277071,"about_ca_system_score_gemma":0.00038289823,"threshold_uncertainty_score":0.99926186},"labels":[],"label_agreement":null},{"id":"W4302293540","doi":"10.3410/f.741524870.793594718","title":"Faculty Opinions recommendation of GPCR kinase knockout cells reveal the impact of individual GRKs on arrestin binding and GPCR regulation.","year":2022,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"G protein-coupled receptor; G protein-coupled receptor kinase; Arrestin; Kinase; Biology; Cell biology; Computational biology; Signal transduction","score_opus":0.026937257205487092,"score_gpt":0.3380481716396187,"score_spread":0.31111091443413164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4302293540","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014204154,0.0010534724,0.000027417133,0.014193729,0.0005350453,0.0010184171,0.98300123,0.000007933547,0.000020719377],"genre_scores_gemma":[0.00039740535,0.0003757132,0.00028478837,0.0006461815,0.0002308047,0.00011511264,0.99757886,0.00002554979,0.00034560804],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99637544,0.00062438514,0.0011587923,0.0005791467,0.0009937711,0.00026844206],"domain_scores_gemma":[0.9955915,0.00011572071,0.0015765853,0.0010677513,0.0014789824,0.00016944786],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0017919055,0.00042245546,0.0006288902,0.00022634957,0.0003046957,0.000087022076,0.0011570374,0.00051362126,0.0013041587],"category_scores_gemma":[0.002304734,0.0002482131,0.0005725813,0.00086971855,0.00024515594,0.000026102545,0.00063367,0.0007258979,0.0000029927457],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003247856,0.00019038611,0.0000047807744,0.0011289223,0.00018927312,1.0410083e-7,0.000084042906,0.000005057711,0.0012151478,0.00007503356,0.9953124,0.0017623799],"study_design_scores_gemma":[0.000475272,0.00047393533,0.0008108719,0.0021594085,0.00013420664,0.00001648459,0.000051230512,0.0000074886784,0.0022260721,0.000021524293,0.9933775,0.00024601477],"about_ca_topic_score_codex":0.000058664376,"about_ca_topic_score_gemma":0.000001958985,"teacher_disagreement_score":0.014577611,"about_ca_system_score_codex":0.000057659883,"about_ca_system_score_gemma":0.00037973444,"threshold_uncertainty_score":0.999997},"labels":[],"label_agreement":null},{"id":"W4302308420","doi":"","title":"Angina (unstable).","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Unstable angina; Cardiology; Myocardial infarction","score_opus":0.01142112025038964,"score_gpt":0.19107691862998089,"score_spread":0.17965579837959125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4302308420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9094716,0.0018066867,0.012501637,0.000090518835,0.00070403144,0.00045663168,0.0000054833217,0.00003016167,0.07493325],"genre_scores_gemma":[0.9948479,0.00004620103,0.00058959716,0.00020143452,0.00009426517,0.00020806208,0.0000111138015,0.000012397777,0.0039890395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994504,0.000026758009,0.000069236194,0.00015966195,0.000058856156,0.00023512235],"domain_scores_gemma":[0.9997417,0.0000023042576,0.000021036627,0.00014618668,0.00002161115,0.00006715864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019529482,0.0000659448,0.000056288813,0.000016920763,0.000040999043,0.000016805683,0.000064613276,0.0000612216,0.000086130734],"category_scores_gemma":[0.00005644488,0.00006183381,0.000044870507,0.000049387654,0.00001182292,0.0000014812111,0.000014822815,0.000030142337,0.000008668516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050402752,0.00012860831,0.0038189192,0.000025426698,0.00012765263,0.000010140593,0.000046799036,0.00011360208,0.8074042,0.024175655,0.017013382,0.1470852],"study_design_scores_gemma":[0.00019763409,0.00001795822,0.0013426963,7.0998493e-7,0.000004907444,0.000007669327,0.0000219037,0.0000028952652,0.6131845,0.00038800758,0.38472006,0.000111049914],"about_ca_topic_score_codex":0.0000021828541,"about_ca_topic_score_gemma":0.0000014738147,"teacher_disagreement_score":0.3677067,"about_ca_system_score_codex":0.000005391507,"about_ca_system_score_gemma":0.000012296513,"threshold_uncertainty_score":0.25215095},"labels":[],"label_agreement":null},{"id":"W4306772922","doi":"10.1002/jmr.2997","title":"Systematic analysis to identify novel disease indications and plausible potential chemical leads of glutamate ionotropic receptor<scp>NMDA</scp>type subunit 1,<scp>GRIN1</scp>","year":2022,"lang":"en","type":"review","venue":"Journal of Molecular Recognition","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"King Khalid University","keywords":"Ionotropic effect; Schizophrenia (object-oriented programming); NMDA receptor; Disease; Glutamate receptor; Protein subunit; Computational biology; Drug discovery; Genetics; Biology; Chemistry; Pharmacology; Bioinformatics; Gene; Receptor; Medicine; Psychiatry; Internal medicine","score_opus":0.027402602246069052,"score_gpt":0.2994095378171673,"score_spread":0.27200693557109823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306772922","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.30888793,0.6672596,0.021870188,0.000011334529,0.00056751526,0.0010158424,0.0003371073,0.000012738069,0.00003776439],"genre_scores_gemma":[0.029816765,0.9629325,0.003946419,0.00008468413,0.00043260492,0.00013539239,0.0023722732,0.00014023589,0.00013909765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963819,0.00045002345,0.0016141863,0.0005186329,0.00069496915,0.00034030288],"domain_scores_gemma":[0.9964362,0.0001497668,0.0021406761,0.0003818999,0.00047649705,0.00041496273],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00083286484,0.00046048363,0.0016211242,0.00087120786,0.0001345588,0.00011323751,0.0004746731,0.00038108983,0.00009747301],"category_scores_gemma":[0.0015298396,0.0004298738,0.0011942993,0.0010234689,0.000054350272,0.000022697706,0.00025272372,0.00049416337,0.000015629743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045276756,0.00060837314,0.000028742572,0.036016997,0.008365595,0.00006534895,0.00012542678,0.00032187006,0.93546486,0.00004830367,0.0005444921,0.018364705],"study_design_scores_gemma":[0.005655935,0.0046503474,0.00020556431,0.078922585,0.13131511,0.0019760376,0.002058589,0.0003419051,0.4819564,0.0010520564,0.28973848,0.002126987],"about_ca_topic_score_codex":0.0000057668703,"about_ca_topic_score_gemma":0.0000012987499,"teacher_disagreement_score":0.45350847,"about_ca_system_score_codex":0.00009725449,"about_ca_system_score_gemma":0.00038535462,"threshold_uncertainty_score":0.9998153},"labels":[],"label_agreement":null},{"id":"W4306973299","doi":"10.3389/fphar.2022.1049022","title":"Editorial: Methods and application in cardiovascular and smooth muscle pharmacology: 2021","year":2022,"lang":"en","type":"editorial","venue":"Frontiers in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Pharmacology; Smooth muscle; Medicine; Clinical pharmacology; Internal medicine","score_opus":0.004916981484145554,"score_gpt":0.29883867957406735,"score_spread":0.2939216980899218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4306973299","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021888071,0.033945974,0.009697939,0.00005057411,0.9532618,0.00069446384,0.00007874004,0.000010955566,0.000070756876],"genre_scores_gemma":[0.00066373206,0.022778759,0.009453679,0.00011073745,0.96532905,0.00084255094,0.0006105751,0.0000881167,0.00012282332],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9965708,0.0010917183,0.0004446673,0.0011261961,0.00029438478,0.0004721854],"domain_scores_gemma":[0.9992446,0.00011979092,0.00017463323,0.0002646274,0.00007779116,0.00011857773],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0021754222,0.0003777155,0.00079323817,0.000299243,0.00010962439,0.000023057564,0.0003353026,0.001169918,0.00017957042],"category_scores_gemma":[0.00011018452,0.00044361147,0.00014989059,0.00021291773,0.00015447832,0.000009001676,0.0004713929,0.0010986221,7.249683e-7],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016803638,0.00005180657,0.00006165889,0.000059729875,0.0002534985,0.0000107575515,0.00006165132,0.00021320666,0.16113572,0.0000012433239,0.8140744,0.023908317],"study_design_scores_gemma":[0.0024141634,0.00017110445,0.000013116309,0.000005931002,0.00023239161,0.0000014752001,0.0001234514,0.0004010975,0.012055559,0.00014555984,0.98403364,0.0004024974],"about_ca_topic_score_codex":0.00013921758,"about_ca_topic_score_gemma":0.000012719129,"teacher_disagreement_score":0.16995928,"about_ca_system_score_codex":0.00014581297,"about_ca_system_score_gemma":0.00024055383,"threshold_uncertainty_score":0.9998016},"labels":[],"label_agreement":null},{"id":"W4308451198","doi":"10.1101/2022.11.06.515338","title":"Rewarding Value or Prediction Error: Settling the debate over the role of dopamine in reward learning","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; McGill University","keywords":"Optogenetics; Mean squared prediction error; Neuroscience; Dopamine; Value (mathematics); Psychology; Reinforcement learning; Blocking (statistics); Conflation; Cognitive psychology; Computer science; Artificial intelligence; Machine learning","score_opus":0.009511554074233411,"score_gpt":0.22156891889009084,"score_spread":0.21205736481585744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308451198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9938405,0.0032313936,0.0013602419,0.00006660458,0.00076342875,0.0005796956,0.000077049575,0.00005960502,0.000021483103],"genre_scores_gemma":[0.99784994,0.0006093807,0.0006386897,0.0000898768,0.00049564545,0.00017532334,0.0000029624518,0.000109810964,0.000028382115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973312,0.0004806698,0.00060170225,0.0007490251,0.00040994422,0.00042743288],"domain_scores_gemma":[0.99825746,0.00007179426,0.0005111858,0.0009470149,0.00013854736,0.000073973555],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016705598,0.00038526798,0.00038322393,0.00013080434,0.00033234572,0.00009871139,0.0006895235,0.0003676743,0.00011226344],"category_scores_gemma":[0.0003465315,0.00027388605,0.00020795125,0.00036691446,0.000086908396,0.00001014132,0.00094043795,0.0010534137,0.0000019796726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107800304,0.00003989293,0.010159332,0.00007972032,0.00012855549,0.000006630744,0.000046860503,0.023638064,0.9655821,0.00015468898,0.00004498571,0.000011394593],"study_design_scores_gemma":[0.0005147446,0.00020117885,0.009747363,0.00027249366,0.000120265286,1.3962821e-7,0.00019624908,0.007410642,0.93342316,0.000007816558,0.04758073,0.00052523083],"about_ca_topic_score_codex":0.0001826782,"about_ca_topic_score_gemma":0.000009897557,"teacher_disagreement_score":0.047535744,"about_ca_system_score_codex":0.00009845461,"about_ca_system_score_gemma":0.0003628907,"threshold_uncertainty_score":0.99997133},"labels":[],"label_agreement":null},{"id":"W4308808050","doi":"10.7554/elife.82711.sa0","title":"Editor's evaluation: Nucleus accumbens dopamine tracks aversive stimulus duration and prediction but not value or prediction error","year":2022,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"","keywords":"Nucleus accumbens; Stimulus (psychology); Mean squared prediction error; Dopamine; Neuroscience; Aversive Stimulus; Psychology; Mathematics; Statistics; Cognitive psychology","score_opus":0.029144226991347867,"score_gpt":0.30320062474748083,"score_spread":0.27405639775613294,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308808050","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.11298579,0.114088245,0.08663502,0.04920122,0.49787492,0.04136604,0.065979876,0.0014082761,0.030460624],"genre_scores_gemma":[0.072204955,0.07215467,0.005966473,0.008118119,0.11291229,0.0035622895,0.1752933,0.0006496937,0.5491382],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9966396,0.00029991797,0.00075527193,0.000960456,0.0010372003,0.00030755813],"domain_scores_gemma":[0.99824613,0.000042597705,0.00046808404,0.0004804034,0.000612624,0.00015016024],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012222846,0.0004488211,0.00045994198,0.00010538904,0.0003537913,0.000076112796,0.0002245756,0.00058704684,0.0074193063],"category_scores_gemma":[0.00051624776,0.00040006262,0.00019487792,0.00014438119,0.00005244683,0.000021147674,0.00021353152,0.0004103909,0.000011802233],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002445241,0.00007985621,0.0000052424443,0.00053859694,0.00022348025,0.0000041927638,0.000040456893,0.0010040265,0.058536313,0.000011900079,0.9332075,0.0061038984],"study_design_scores_gemma":[0.0011704264,0.0013496801,0.0000518892,0.00031550523,0.00081868214,0.00007746762,0.00020231456,0.008177044,0.021240942,0.000018376862,0.96612734,0.00045033018],"about_ca_topic_score_codex":0.00008817824,"about_ca_topic_score_gemma":0.000051914667,"teacher_disagreement_score":0.5186776,"about_ca_system_score_codex":0.00018036528,"about_ca_system_score_gemma":0.00045324996,"threshold_uncertainty_score":0.99984515},"labels":[],"label_agreement":null},{"id":"W4309575799","doi":"10.7554/elife.81286","title":"Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor","year":2022,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; Cancer Prevention and Research Institute of Texas; Welch Foundation","keywords":"Insulin-like growth factor 1 receptor; Insulin receptor; Chemistry; Receptor; Dimer; Insulin-like growth factor; Ligand (biochemistry); Insulin; Insulin-like growth factor 2 receptor; Biophysics; Growth factor; Biochemistry; Biology; Insulin resistance; Endocrinology","score_opus":0.010686409279447149,"score_gpt":0.22953488066029967,"score_spread":0.21884847138085253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309575799","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951134,0.002035009,0.0016448742,0.0003690258,0.00014080573,0.0005245882,0.0001323919,0.0000041258127,0.000035788467],"genre_scores_gemma":[0.9980156,0.0004874456,0.00077670807,0.000332327,0.000079132,0.00016633685,0.000104538885,0.000020963149,0.000016990902],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885726,0.00017844573,0.00030559915,0.00023853929,0.00026302907,0.0001571378],"domain_scores_gemma":[0.9992786,0.00014227473,0.00019247145,0.00025085008,0.00010606227,0.000029717678],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054168387,0.00012706703,0.00016978644,0.00004878392,0.000121602636,0.000011966582,0.0002913012,0.00008056175,0.000079486395],"category_scores_gemma":[0.0003214744,0.00008915484,0.000098255965,0.00017354895,0.00004824019,0.000005954311,0.0001291807,0.00012757129,4.5606248e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022434919,0.00008075529,0.00040414775,0.000018884952,0.000042690128,9.100645e-8,0.0007027517,0.00014078007,0.9917112,0.00064632914,0.00016797514,0.0058600474],"study_design_scores_gemma":[0.0005635572,0.00038528384,0.0008554676,0.00001267196,0.000013844453,8.184672e-7,0.0018886239,0.0002623101,0.97072643,0.00014969,0.025024477,0.000116853174],"about_ca_topic_score_codex":0.00006862047,"about_ca_topic_score_gemma":0.000004728916,"teacher_disagreement_score":0.024856502,"about_ca_system_score_codex":0.00001664923,"about_ca_system_score_gemma":0.00006371252,"threshold_uncertainty_score":0.3635629},"labels":[],"label_agreement":null},{"id":"W4310020999","doi":"10.1016/j.bbrep.2022.101397","title":"Distal extracellular teneurin region (teneurin C-terminal associated peptide; TCAP) possesses independent intracellular calcium regulating actions, in vitro: A potential antagonist of corticotropin-releasing factor (CRF)","year":2022,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Protagonist Therapeutics","keywords":"Extracellular; Biology; Calcium in biology; Cell biology; Calcium; Cytosol; Intracellular; Biochemistry; Internal medicine; Medicine; Enzyme","score_opus":0.014707604573176769,"score_gpt":0.23956568868705436,"score_spread":0.2248580841138776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310020999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99753594,0.0009798771,0.0007967379,0.00002979854,0.0002832256,0.00025206062,0.00007133162,0.000020806956,0.00003024291],"genre_scores_gemma":[0.998294,0.0002049851,0.00017853457,0.000011053919,0.00018218668,0.000043818087,0.00057485286,0.0000409089,0.0004696571],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99760985,0.000103421924,0.0007319401,0.000750874,0.00042164655,0.000382236],"domain_scores_gemma":[0.9986167,0.000012573781,0.0007326387,0.00040229486,0.0001144891,0.00012132107],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000058730166,0.0003188432,0.000367949,0.000062729334,0.0003267629,0.00006835005,0.00014904237,0.00020445908,0.00002192842],"category_scores_gemma":[0.00006461107,0.00035076519,0.00019282196,0.00019490188,0.00012268635,0.000017568556,0.00030380694,0.00032597475,1.3003768e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002445654,0.00036339829,0.001825649,0.00011351642,0.00006107458,0.0007454671,0.00003562005,0.00022693114,0.9945334,0.00000632021,0.000014284677,0.001829764],"study_design_scores_gemma":[0.0004248005,0.00016081236,0.0020089159,0.00004246102,0.000045577726,0.0010298889,0.00032080244,0.0003359148,0.99502033,0.000049831862,0.00018105324,0.00037961913],"about_ca_topic_score_codex":0.00011139092,"about_ca_topic_score_gemma":0.0000017032683,"teacher_disagreement_score":0.0014501449,"about_ca_system_score_codex":0.00008355839,"about_ca_system_score_gemma":0.0001522339,"threshold_uncertainty_score":0.99989444},"labels":[],"label_agreement":null},{"id":"W4310208892","doi":"10.3389/fncel.2022.1076599","title":"Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice","year":2022,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; McGill University; Douglas Mental Health University Institute","funders":"National Institute of Mental Health; Fonds de Recherche du Québec - Santé; University of California, San Francisco; Canada Research Chairs; Langley Research Center; Institut National de la Santé et de la Recherche Médicale; Canadian Institutes of Health Research; Québec Consortium for Drug Discovery; McGill University","keywords":"Ventral tegmental area; Substantia nigra; Cell biology; G protein-coupled receptor; Receptor; Dopamine receptor D2; Dopamine; Chemistry; Biology; Neuroscience; Dopaminergic; Signal transduction; Biochemistry","score_opus":0.007156644851505155,"score_gpt":0.2196090651266273,"score_spread":0.21245242027512215,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310208892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925484,0.00046850066,0.005580653,0.00003659009,0.000852634,0.00028633277,0.00003990317,0.000008244976,0.00017871495],"genre_scores_gemma":[0.9975975,0.00041958573,0.00089632976,0.00009565099,0.000023659944,0.000049553822,0.00009085577,0.000026916647,0.00079993374],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980587,0.00031890403,0.00039371368,0.0005868409,0.00028367384,0.0003581926],"domain_scores_gemma":[0.9995167,0.000014156375,0.00015140425,0.00024054067,0.000021048058,0.000056117042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050968264,0.00015487781,0.00023502628,0.00024082058,0.00008133813,0.000016353704,0.0004380946,0.000065732216,0.00005956564],"category_scores_gemma":[0.00012738828,0.00018446606,0.000056601544,0.0007862919,0.00007640381,0.000013300989,0.00021053816,0.000150382,9.442143e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065124106,0.00015589305,0.004760851,0.000011787726,0.0000010654995,0.000013783456,0.000071286704,0.002293871,0.9910018,0.000012251363,0.0013005853,0.0003117245],"study_design_scores_gemma":[0.00059836917,0.00032317755,0.00021433804,0.000011794369,0.000003059069,0.000003500086,0.00011681768,0.00830935,0.9807917,0.000027071264,0.009416395,0.0001844521],"about_ca_topic_score_codex":0.0001206742,"about_ca_topic_score_gemma":0.0000068227446,"teacher_disagreement_score":0.010210101,"about_ca_system_score_codex":0.00006745688,"about_ca_system_score_gemma":0.00007715047,"threshold_uncertainty_score":0.7522307},"labels":[],"label_agreement":null},{"id":"W4310540339","doi":"10.1038/s41467-022-34055-5","title":"Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"U.S. National Library of Medicine; National Institutes of Health; Lundbeckfonden; H. Lundbeck A/S; Novo Nordisk Fonden; National Institute of General Medical Sciences; Medical Research Council; Novo Nordisk; Canadian Institutes of Health Research; American Lebanese Syrian Associated Charities","keywords":"G protein-coupled receptor; Computational biology; Protein–protein interaction; Coupling (piping); Biology; G protein; Promiscuity; Receptor; Bioinformatics; Chemistry; Cell biology; Genetics; Materials science","score_opus":0.010929708925905914,"score_gpt":0.2782167107239214,"score_spread":0.2672870017980155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310540339","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99600863,0.002567499,0.00052651326,0.00029090978,0.00006187961,0.00039049805,0.000040966523,0.00002074184,0.00009236065],"genre_scores_gemma":[0.99481094,0.000102302394,0.004417211,0.000066480214,0.000015888167,0.00015665834,0.00020144529,0.000018398745,0.00021070185],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992677,0.00010359218,0.00013561478,0.0002360457,0.000115557516,0.00014147963],"domain_scores_gemma":[0.9990499,0.000012675958,0.000093021496,0.0007364099,0.00006428735,0.00004370645],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034355538,0.0001029638,0.00010312293,0.000034911944,0.00067573396,0.000025543348,0.00042955737,0.00013599268,0.0000207804],"category_scores_gemma":[0.000053419604,0.000108434346,0.000037965496,0.0001031945,0.00004965433,0.0000053782032,0.00068254,0.0005425243,7.2875196e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002819015,0.00010372781,0.0027871125,0.00001064407,0.000025254241,7.240593e-7,0.000065318156,0.00024332904,0.9934826,0.0003890849,0.00008983617,0.0027741601],"study_design_scores_gemma":[0.0019448512,0.0010267731,0.020752238,0.00005499051,0.000088032044,0.00011793488,0.00043641886,0.30708322,0.5816042,0.0026929702,0.08280837,0.0013899957],"about_ca_topic_score_codex":0.000026530324,"about_ca_topic_score_gemma":0.00028483337,"teacher_disagreement_score":0.4118784,"about_ca_system_score_codex":0.000032452994,"about_ca_system_score_gemma":0.00006843227,"threshold_uncertainty_score":0.51972675},"labels":[],"label_agreement":null},{"id":"W4310680528","doi":"10.15252/emmm.202217003","title":"Targeting conformational changes in C‐reactive protein to inhibit pro‐inflammatory actions","year":2022,"lang":"en","type":"article","venue":"EMBO Molecular Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research","keywords":"Inflammation; C-reactive protein; Cell biology; Phosphocholine; Chemistry; Medicine; Immunology; Biology; Biochemistry","score_opus":0.011869760184527393,"score_gpt":0.25396466865467,"score_spread":0.2420949084701426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310680528","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877423,0.00033549513,0.006555903,0.0025399427,0.00020719228,0.00084896217,0.000014410874,0.000019727364,0.0017360377],"genre_scores_gemma":[0.9963524,0.000004952877,0.00073586364,0.0014386964,0.00024774016,0.0005659194,0.00025532854,0.000026233554,0.00037288765],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987609,0.000106648426,0.0002449335,0.00028844288,0.00034504323,0.0002540246],"domain_scores_gemma":[0.999539,0.0000072392318,0.000096295655,0.00018421638,0.00007116383,0.000102060614],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00050637097,0.00014873607,0.00016828526,0.00016286322,0.00015300163,0.000008420129,0.00016017677,0.00005922706,0.00066190417],"category_scores_gemma":[0.00015250346,0.0001469799,0.000036852016,0.00020957415,0.000031853182,0.0000050143694,0.00016830911,0.0002099228,0.0000074945833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006374232,0.00002959299,0.000045829387,0.000014512122,0.000020584052,0.000019193396,0.0004964545,0.0013228577,0.9958218,0.000833624,0.00080660824,0.0005252288],"study_design_scores_gemma":[0.0008659082,0.0006426927,0.000109027795,0.000047973244,0.000009314982,0.00002107855,0.0021373471,0.00025758398,0.9154898,0.00017389671,0.08001255,0.00023285102],"about_ca_topic_score_codex":0.000028798608,"about_ca_topic_score_gemma":0.000015982145,"teacher_disagreement_score":0.080331996,"about_ca_system_score_codex":0.000064404245,"about_ca_system_score_gemma":0.00008964749,"threshold_uncertainty_score":0.72473866},"labels":[],"label_agreement":null},{"id":"W4311284663","doi":"10.1021/acs.jproteome.2c00707","title":"Phosphoproteomic Analysis of Dopamine D2 Receptor Signaling Reveals Interplay of G Protein- and β-Arrestin-Mediated Effects","year":2022,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"Canadian Cancer Society Research Institute; Canada Research Chairs; Deutsche Forschungsgemeinschaft; Ontario Ministry of Health and Long-Term Care","keywords":"Agonist; Arrestin; Dopamine receptor D2; Phosphoproteomics; Phosphorylation; Quinpirole; Signal transduction; Biology; Cell biology; Receptor; G protein-coupled receptor; Dopamine receptor; Protein kinase A; Chemistry; Protein phosphorylation; Biochemistry","score_opus":0.01625596902457213,"score_gpt":0.3153310806471857,"score_spread":0.2990751116226136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311284663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943995,0.0021100906,0.0024929496,0.000076396114,0.00007704752,0.0007937118,0.000028916818,0.000002454935,0.000018967028],"genre_scores_gemma":[0.99482423,0.00012197542,0.004564564,0.000008728737,0.00010764197,0.00008674748,0.000021808024,0.000026055244,0.00023825985],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9968248,0.00080953474,0.0008098009,0.0002710843,0.00095260807,0.00033218245],"domain_scores_gemma":[0.9979349,0.00017585079,0.00072025874,0.0002638566,0.0007511776,0.00015395354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0052622026,0.00015142215,0.0005925323,0.00079622475,0.00014469126,0.000022280905,0.00042456354,0.00010452589,0.00037241555],"category_scores_gemma":[0.0012842219,0.00012988821,0.00025716217,0.0010981077,0.00014066092,0.000011219465,0.00038259928,0.0005877456,7.8728664e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00085087324,0.00013767189,0.0014183919,0.00021605336,0.00071316666,0.000011879262,0.000143845,0.000455343,0.9947298,0.000016444199,0.00008140328,0.0012251177],"study_design_scores_gemma":[0.00078720273,0.003222767,0.00031078325,0.00015995822,0.000103594015,0.000018776604,0.00027244719,0.00030682,0.9940502,0.00010223483,0.0005431977,0.00012203693],"about_ca_topic_score_codex":0.00004879903,"about_ca_topic_score_gemma":0.0000019590655,"teacher_disagreement_score":0.0039779805,"about_ca_system_score_codex":0.00006032379,"about_ca_system_score_gemma":0.00022877254,"threshold_uncertainty_score":0.52966875},"labels":[],"label_agreement":null},{"id":"W4311650374","doi":"10.1126/scisignal.add2519","title":"Synaptic activity–dependent changes in the hippocampal palmitoylome","year":2022,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Palmitoylation; Synaptic plasticity; Long-term potentiation; Biology; Cell biology; Neuroscience; Synaptic fatigue; Nonsynaptic plasticity; Postsynaptic density; Synapse; Metaplasticity; Synaptic augmentation; Synaptic scaling; Chemistry; Biochemistry; Receptor; Cysteine","score_opus":0.014198891742345041,"score_gpt":0.2527714817088898,"score_spread":0.23857258996654476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4311650374","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99782103,0.00022861059,0.000796971,0.00032281748,0.00034244376,0.00017914765,0.0000050631056,0.000008105954,0.00029578025],"genre_scores_gemma":[0.99911433,0.000011351484,0.00016364739,0.00042067392,0.00014795367,0.000077230216,0.0000049401124,0.000009371394,0.000050510258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983486,0.00015579254,0.00011103007,0.00041176565,0.0005813283,0.00039148307],"domain_scores_gemma":[0.9995523,0.00002509711,0.00006511051,0.00027716166,0.000030800988,0.00004952943],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023499033,0.00010870205,0.00009314658,0.00011579314,0.00062277244,0.00008032057,0.0007405338,0.000031423904,0.00022287393],"category_scores_gemma":[0.00006513318,0.00008628319,0.000043727516,0.0004819276,0.00012384613,0.000007835562,0.00028330012,0.00020005155,0.0000039631136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016672479,0.000033944085,0.00017978228,0.0000028222257,0.000005343713,0.000008608395,0.00051300426,0.0024573887,0.9945212,0.00015561556,0.000011850611,0.00209376],"study_design_scores_gemma":[0.00022451725,0.00041283047,0.00017715775,0.0000067439532,0.0000066626953,0.000047965386,0.002846959,0.00093342527,0.99321634,0.0005061982,0.0014157784,0.00020543161],"about_ca_topic_score_codex":0.000032409414,"about_ca_topic_score_gemma":0.000026490146,"teacher_disagreement_score":0.002333955,"about_ca_system_score_codex":0.00004854563,"about_ca_system_score_gemma":0.000143586,"threshold_uncertainty_score":0.47899252},"labels":[],"label_agreement":null},{"id":"W4312008696","doi":"10.3389/fnume.2022.1030387","title":"Transient equilibrium determination of dopamine D2/D3 receptor densities and affinities in brain","year":2022,"lang":"en","type":"article","venue":"Frontiers in Nuclear Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institutes of Health","keywords":"Radioligand; Putamen; Raclopride; Receptor; Binding potential; Caudate nucleus; Chemistry; Dopamine receptor; Neuroscience; Biology; Biochemistry","score_opus":0.007394638998571023,"score_gpt":0.21559744817108567,"score_spread":0.20820280917251466,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312008696","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995139,0.0017014277,0.0014268217,0.0008155832,0.0005387921,0.000137104,0.000008521831,0.0000057546818,0.00022698466],"genre_scores_gemma":[0.9962926,0.00020066148,0.0026890151,0.00032758055,0.00008535127,0.000010869835,0.000048354916,0.000021648653,0.00032392074],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99914646,0.00010475243,0.00024742703,0.000197158,0.00015679582,0.00014739911],"domain_scores_gemma":[0.9997532,0.00001520468,0.00006702103,0.00011054986,0.000020725098,0.000033308872],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040763518,0.00009625381,0.00021107333,0.00016776053,0.000034544595,0.0000036181723,0.000095306816,0.000053614905,0.00018340755],"category_scores_gemma":[0.00006833791,0.000096377415,0.000025171785,0.00010869019,0.00011880577,0.0000052051582,0.00007192484,0.00010674957,1.7936588e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003172409,0.000051644372,0.0013632487,0.000067327404,0.000012481755,0.000008221215,0.003454876,0.00012355771,0.96936697,0.00009381254,0.010537693,0.01460291],"study_design_scores_gemma":[0.015617717,0.011099052,0.00588975,0.0006685201,0.00009485829,0.0001317284,0.14996994,0.033969894,0.23833711,0.0016174108,0.54102033,0.0015836703],"about_ca_topic_score_codex":0.000040850744,"about_ca_topic_score_gemma":0.000012522402,"teacher_disagreement_score":0.73102987,"about_ca_system_score_codex":0.000029366287,"about_ca_system_score_gemma":0.000018744006,"threshold_uncertainty_score":0.39301568},"labels":[],"label_agreement":null},{"id":"W4312086944","doi":"10.1002/alz.069154","title":"In vivo imaging of the mouse cholinergic projection system using [<sup>18</sup>F]FEOBV","year":2022,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Lawson Health Research Institute; Western University","funders":"","keywords":"Cholinergic; Vesicular acetylcholine transporter; In vivo; Forebrain; Positron emission tomography; Cholinergic neuron; Chemistry; Biology; Neuroscience; Choline acetyltransferase; Central nervous system; Genetics","score_opus":0.017499534749542803,"score_gpt":0.24970536073629343,"score_spread":0.23220582598675063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312086944","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891058,0.009091141,0.0007517066,0.00003582921,0.0003317597,0.00034008166,0.000019036095,0.0000113505275,0.00031328129],"genre_scores_gemma":[0.99910593,0.000011094895,0.0005485287,0.00010601421,0.000111799585,0.00004452512,0.000014040401,0.000025145724,0.000032945336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989046,0.00014748251,0.00027968007,0.00026864008,0.00019311269,0.00020650816],"domain_scores_gemma":[0.9995105,0.0000034642505,0.00014295976,0.00027924782,0.00003896467,0.000024835012],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031941,0.00012338356,0.000123005,0.000059588674,0.00018842264,0.000016132257,0.00022809552,0.000038705468,0.0002439413],"category_scores_gemma":[0.000005595772,0.00010851595,0.00010455545,0.00017260536,0.00002435684,0.000008070328,0.00027171324,0.00010754965,8.2848584e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025879563,0.000046101297,0.0017292949,0.00000808653,0.0005003287,0.0000018499909,0.00012492077,0.017135857,0.97938746,0.00011422996,0.00062636315,0.0002996389],"study_design_scores_gemma":[0.000384693,0.000043454882,0.00003267943,0.000009770241,0.0006104336,0.000027066939,0.00083815237,0.021480305,0.9707716,0.000011871893,0.005638836,0.00015111337],"about_ca_topic_score_codex":0.0003018257,"about_ca_topic_score_gemma":0.000008599292,"teacher_disagreement_score":0.010000092,"about_ca_system_score_codex":0.000012897232,"about_ca_system_score_gemma":0.000057420995,"threshold_uncertainty_score":0.4425152},"labels":[],"label_agreement":null},{"id":"W4312187006","doi":"10.3389/fnbeh.2022.1008623","title":"Alterations in prefrontal cortical neuregulin-1 levels in post-pubertal rats with neonatal ventral hippocampal lesions","year":2022,"lang":"en","type":"article","venue":"Frontiers in Behavioral Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Japan Society for the Promotion of Science","keywords":"Prefrontal cortex; Hippocampal formation; Prepulse inhibition; Neuregulin 1; Hippocampus; Neuroscience; Lesion; ERBB4; Internal medicine; Psychology; Schizophrenia (object-oriented programming); Endocrinology; Receptor; Medicine; Receptor tyrosine kinase; Psychiatry; Cognition","score_opus":0.018832937433223677,"score_gpt":0.2623338582859698,"score_spread":0.2435009208527461,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312187006","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99635184,0.00008817571,0.0020487292,0.000096692354,0.00096307654,0.00032244937,0.000110531815,0.000008024991,0.000010487713],"genre_scores_gemma":[0.9972493,0.000005324141,0.002146223,0.0002528253,0.00003054782,0.000099752615,0.00008501884,0.000018737413,0.00011224685],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99817234,0.0001772943,0.000285645,0.00058912684,0.0003083187,0.00046728816],"domain_scores_gemma":[0.9996002,0.000005783179,0.00005444776,0.0002130531,0.000021233458,0.00010533939],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019733894,0.00017131974,0.00017449098,0.0001668778,0.00019713747,0.000045323897,0.00035747365,0.00006549415,0.000041016418],"category_scores_gemma":[0.000031242365,0.00017376467,0.000050713417,0.00038291767,0.0001504074,0.000030080637,0.0001956603,0.00041974016,4.722221e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023007848,0.00036045772,0.10212092,0.0000020239386,8.035663e-7,0.00024025158,0.00034659132,0.004538365,0.8905025,0.000031057665,0.00008662111,0.0015403368],"study_design_scores_gemma":[0.0033564104,0.0045659533,0.7658433,0.00003751032,0.000022495118,0.00034057198,0.003495677,0.008881165,0.21100916,0.00010152978,0.0012742963,0.0010719587],"about_ca_topic_score_codex":0.000099223085,"about_ca_topic_score_gemma":0.0005298445,"teacher_disagreement_score":0.6794933,"about_ca_system_score_codex":0.00008144801,"about_ca_system_score_gemma":0.00020666436,"threshold_uncertainty_score":0.7085917},"labels":[],"label_agreement":null},{"id":"W4312203731","doi":"10.1038/s41467-022-35601-x","title":"Continuous cholinergic-dopaminergic updating in the nucleus accumbens underlies approaches to reward-predicting cues","year":2022,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Western University","funders":"Canadian Institutes of Health Research; Canada First Research Excellence Fund; Canadian Institute for Advanced Research","keywords":"Nucleus accumbens; Neuroscience; Dopaminergic; Vesicular acetylcholine transporter; Dopamine; Acetylcholine; Neurochemical; Cholinergic; Medium spiny neuron; Dopamine transporter; Psychology; Striatum; Biology; Pharmacology; Choline acetyltransferase","score_opus":0.05938093382806944,"score_gpt":0.28720562785210946,"score_spread":0.22782469402404001,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312203731","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97994363,0.004807131,0.00028624412,0.0054517575,0.00020893328,0.000445685,0.00007833124,0.000040598137,0.008737688],"genre_scores_gemma":[0.99205077,0.0001488731,0.005451934,0.0013788221,0.00012399477,0.00020854724,0.00046954784,0.000023428005,0.00014409075],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987359,0.00036277407,0.00024337044,0.0002503854,0.00019264955,0.000214914],"domain_scores_gemma":[0.9985078,0.0000959487,0.00009768159,0.0012175594,0.000042479744,0.00003853101],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00074468734,0.00012900797,0.00012947764,0.000069810856,0.0006521856,0.00005980609,0.0015023864,0.00011926239,0.000028913815],"category_scores_gemma":[0.00019385554,0.000110583045,0.00006790627,0.00031039282,0.000042423777,0.0000057853763,0.0009720503,0.00079633936,0.0000025032148],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002284369,0.0016081568,0.03936799,0.000053031144,0.00033872333,0.000018286115,0.01716608,0.04327462,0.6725946,0.17233782,0.03644041,0.016571863],"study_design_scores_gemma":[0.0013252106,0.00062618,0.005452371,0.000044831435,0.000080147525,0.00013646366,0.068279386,0.006358096,0.018493934,0.0012950702,0.89690846,0.0009998269],"about_ca_topic_score_codex":0.00004894904,"about_ca_topic_score_gemma":0.00039528034,"teacher_disagreement_score":0.8604681,"about_ca_system_score_codex":0.000029854771,"about_ca_system_score_gemma":0.00004130741,"threshold_uncertainty_score":0.501615},"labels":[],"label_agreement":null},{"id":"W4312213379","doi":"10.1101/2022.12.27.522013","title":"Improved genetically encoded fluorescent biosensors for monitoring of intra- and extracellular L-lactate","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Université Laval; University of Toronto","funders":"Precursory Research for Embryonic Science and Technology; Japan Society for the Promotion of Science; National Institutes of Health; Toyota Physical and Chemical Research Institute; University of Tokyo; Japan Science and Technology Agency; Precise Measurement Technology Promotion Foundation; Montana State University","keywords":"Extracellular; Fluorescence; Intracellular; Biosensor; Biochemistry; Green fluorescent protein; Metabolite; Biophysics; In vitro; Membrane; Biology; Chemistry; Cell biology; Gene","score_opus":0.011188740335034475,"score_gpt":0.2234010693104416,"score_spread":0.21221232897540712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312213379","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9794869,0.004836033,0.013300061,0.000040219205,0.0010600566,0.0009610666,0.00026883432,0.0000456079,0.0000012543411],"genre_scores_gemma":[0.9597581,0.0013107575,0.038029354,0.000021634298,0.00050197315,0.0002285184,0.000002547413,0.00013628376,0.000010837627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997516,0.00011140235,0.0006092975,0.0010202255,0.0002450448,0.0004980413],"domain_scores_gemma":[0.99814194,0.000031412783,0.00041680253,0.0008200836,0.00036329663,0.00022643077],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055047555,0.00047978738,0.0005109742,0.00013053468,0.00015679815,0.00008054838,0.00042387453,0.00048284797,0.00003334259],"category_scores_gemma":[0.00018658093,0.00053395436,0.00022152123,0.00011868945,0.000088164896,0.0000055811333,0.0006084425,0.0003736055,4.130212e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013085692,0.00008443157,0.0012318541,0.00038137578,0.0001820883,0.00000521949,0.000009125329,0.0001394697,0.99763596,0.00016665005,0.000021605061,0.0000113787155],"study_design_scores_gemma":[0.00060418766,0.0002924106,0.0010256313,0.00009472095,0.000108846216,2.3780936e-8,0.000014102496,0.0010976823,0.9941983,0.0000030255214,0.0020017899,0.00055927085],"about_ca_topic_score_codex":0.000016121778,"about_ca_topic_score_gemma":4.593367e-7,"teacher_disagreement_score":0.024729293,"about_ca_system_score_codex":0.00005026425,"about_ca_system_score_gemma":0.00029595982,"threshold_uncertainty_score":0.9997112},"labels":[],"label_agreement":null},{"id":"W4313122926","doi":"10.2139/ssrn.4239119","title":"Distal Extracellular Teneurin Region (Teneurin C-Terminal Associated Peptide; TCAP) Possesses Independent Intracellular Calcium Regulating Actions, in Vitro: A Novel Antagonist of Corticotropin-Releasing Factor (CRF)","year":2022,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Extracellular; Antagonist; In vitro; Intracellular; Calcium in biology; Peptide; Cell biology; Corticotropin-releasing hormone; Calcium; Chemistry; Biology; Internal medicine; Receptor; Medicine; Biochemistry","score_opus":0.01867305978265335,"score_gpt":0.25127272328475914,"score_spread":0.23259966350210579,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313122926","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97663724,0.0031941219,0.019449407,0.00008695334,0.0003016467,0.0002632114,0.00003229934,0.000015390293,0.00001972709],"genre_scores_gemma":[0.9970982,0.0015902288,0.00019277772,0.000017368477,0.00019523405,0.000027644412,0.00011607697,0.000066276436,0.00069616124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963546,0.00028684395,0.0007982941,0.0005000368,0.0005432229,0.0015170278],"domain_scores_gemma":[0.9987277,0.000027365137,0.00073227164,0.00027290045,0.00012676636,0.00011299672],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024018898,0.0003141682,0.0003930708,0.00019960683,0.0005087657,0.000077783014,0.0003741435,0.00016944874,0.000037267855],"category_scores_gemma":[0.00011395166,0.00033603256,0.00026671682,0.0002561345,0.000066157016,0.000028400664,0.00020078372,0.0016918961,5.44848e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004807859,0.0004088112,0.0018640499,0.000019862919,0.00013736804,0.000055859207,0.000073704854,0.0014530995,0.9910834,0.00053201756,0.0000047645594,0.0038863132],"study_design_scores_gemma":[0.0024487227,0.0012402607,0.0028601573,0.00005860554,0.00008521426,0.0030831667,0.002660883,0.0013695514,0.9840279,0.00086864276,0.00067850907,0.0006183854],"about_ca_topic_score_codex":0.00019637488,"about_ca_topic_score_gemma":0.00012569122,"teacher_disagreement_score":0.02046099,"about_ca_system_score_codex":0.0007490573,"about_ca_system_score_gemma":0.0010411114,"threshold_uncertainty_score":0.99990916},"labels":[],"label_agreement":null},{"id":"W4313354918","doi":"10.4049/jimmunol.190.supp.59.8","title":"Functional expression of the novel C5a receptor C5L2 in human mast cells (P6014)","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada; Health PEI; National Institute for Nanotechnology","funders":"","keywords":"Degranulation; Chemotaxis; Cell biology; G protein-coupled receptor; Receptor; Chemokine; Immune system; Molecular biology; Biology; Signal transduction; Immunology; Biochemistry","score_opus":0.010457878609987616,"score_gpt":0.20895298432042514,"score_spread":0.19849510571043752,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313354918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99649453,0.00067564653,0.001720437,0.00028914073,0.0006001703,0.00009246968,0.0000023384055,0.0000010084328,0.00012424229],"genre_scores_gemma":[0.9987716,0.00012529331,0.00036795557,0.000088292196,0.00016057705,0.000002595181,0.000002544753,0.000010218303,0.00047089971],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99914575,0.00015217236,0.0003676272,0.00007520107,0.000116353156,0.00014288544],"domain_scores_gemma":[0.9992282,0.000027774115,0.00036639924,0.00021849849,0.00014031763,0.000018820081],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040133914,0.00009000268,0.0001508625,0.00004323122,0.000075793425,0.0000066175753,0.00036243116,0.00012616884,0.00062839227],"category_scores_gemma":[0.000035137593,0.000048129616,0.00010385152,0.00006114124,0.00010598655,0.000006592125,0.00012955637,0.0002320017,0.000007215525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008547597,0.000059291673,0.00009933701,0.0000029028868,0.00003138124,1.226058e-7,0.000089206325,0.00027112005,0.9973501,0.00006864278,0.001683702,0.00025871865],"study_design_scores_gemma":[0.0005588538,0.00027155833,0.0026935365,0.00003714899,0.000009257511,0.00003570445,0.00035189185,0.0000064491383,0.9937125,0.00020284712,0.0020656425,0.000054617023],"about_ca_topic_score_codex":0.000034818666,"about_ca_topic_score_gemma":0.0000042639,"teacher_disagreement_score":0.0036376058,"about_ca_system_score_codex":0.000014050399,"about_ca_system_score_gemma":0.000045958113,"threshold_uncertainty_score":0.68804544},"labels":[],"label_agreement":null},{"id":"W4313484226","doi":"10.48550/arxiv.2301.00512","title":"On the Challenges of using Reinforcement Learning in Precision Drug Dosing: Delay and Prolongedness of Action Effects","year":2023,"lang":"en","type":"preprint","venue":"arXiv (Cornell University)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut de Valorisation des Données","keywords":"Reinforcement learning; Partially observable Markov decision process; Markov decision process; Dosing; Computer science; Task (project management); Action (physics); Markov chain; Markov process; Artificial intelligence; Machine learning; Markov model; Medicine; Pharmacology; Mathematics","score_opus":0.08451059916471947,"score_gpt":0.22447861140579106,"score_spread":0.13996801224107158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313484226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908295,0.00020901058,0.008452411,0.000012327371,0.00014444563,0.0002783842,9.286546e-7,0.000006889788,0.00006609572],"genre_scores_gemma":[0.9987892,0.0010237062,0.000038328555,0.0000044808257,0.000021825934,0.0000010915926,0.000006514053,0.000014175593,0.00010069139],"study_design_codex":"simulation_or_modeling","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99918944,0.0001575558,0.00013937148,0.0003456804,0.000057054713,0.00011089627],"domain_scores_gemma":[0.9993927,0.00008050126,0.00022501631,0.00022572478,0.00005380629,0.000022291915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038346366,0.00013057335,0.0001785949,0.000103774386,0.000047313388,0.0000063115226,0.00014440398,0.00017755911,0.0000028098139],"category_scores_gemma":[0.000074658616,0.00011537136,0.00006874184,0.00008227685,0.000043157987,0.0000038491894,0.0003260354,0.00021306645,3.7773884e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002969229,0.000038545546,0.0010800371,0.00038380243,0.00007940843,0.000009515535,0.0003811937,0.70879126,0.28349397,0.004811937,0.0000038211297,0.0006295806],"study_design_scores_gemma":[0.0009325171,0.0005170796,0.0013875586,0.0014720865,0.0001077474,0.0000016285824,0.00126161,0.15805131,0.82970446,0.006160744,0.000030453723,0.00037280936],"about_ca_topic_score_codex":0.00010964556,"about_ca_topic_score_gemma":0.000032538326,"teacher_disagreement_score":0.55073994,"about_ca_system_score_codex":0.000027358812,"about_ca_system_score_gemma":0.000040474093,"threshold_uncertainty_score":0.47047076},"labels":[],"label_agreement":null},{"id":"W4313640794","doi":"10.1038/s41380-022-01928-6","title":"Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signalling","year":2023,"lang":"en","type":"article","venue":"HAL (Le Centre pour la Communication Scientifique Directe)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"Instituto de Salud Carlos III; Novo Nordisk Fonden; Université de Bordeaux; National Institute of Mental Health; Centre National de la Recherche Scientifique; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement; Brain and Behavior Research Foundation; Agence Nationale de la Recherche; Ministerio de Economía y Competitividad; U.S. Department of Health and Human Services","keywords":"Dopamine receptor D2; Docosahexaenoic acid; Polyunsaturated fatty acid; Allosteric regulation; Dopamine; Chemistry; Receptor; Dopamine receptor; Pharmacology; Biochemistry; Biology; Neuroscience; Fatty acid","score_opus":0.010652049222481799,"score_gpt":0.23622548204086546,"score_spread":0.22557343281838366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313640794","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925847,0.00016856786,0.0054468713,0.00047473787,0.00007027689,0.00012635301,0.000023262011,0.00003465762,0.0010705873],"genre_scores_gemma":[0.9948738,0.00063337735,0.0022701654,0.000013402274,0.000038807357,0.000007286424,0.00037656844,0.000022048687,0.0017645197],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985898,0.0005383907,0.00022727298,0.00030554386,0.00015494984,0.00018400894],"domain_scores_gemma":[0.99885964,0.00018447444,0.00015985007,0.0003582528,0.00035378837,0.000084006395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015226249,0.00013528657,0.00014745939,0.000111976406,0.00015308136,0.000067376364,0.00017863192,0.0001091246,0.00005684068],"category_scores_gemma":[0.0004144112,0.00012482789,0.00009727608,0.00026423435,0.000057638445,0.000010953379,0.00010235632,0.00009202783,0.000011934139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027117192,0.000053679614,0.00063112867,0.000016999016,0.000032786906,3.5085714e-7,0.0004280587,0.0000765534,0.9911982,0.00093151664,0.00014728443,0.006456361],"study_design_scores_gemma":[0.00032123167,0.000005755208,0.0008476346,0.00019432823,0.000008361762,0.0000025151737,0.00005309029,0.0018158408,0.995907,0.000046825153,0.00066713046,0.00013025446],"about_ca_topic_score_codex":0.00009181058,"about_ca_topic_score_gemma":0.00003860041,"teacher_disagreement_score":0.0063261064,"about_ca_system_score_codex":0.000016694281,"about_ca_system_score_gemma":0.000052294203,"threshold_uncertainty_score":0.5090334},"labels":[],"label_agreement":null},{"id":"W4315702519","doi":"10.1007/s00210-022-02378-1","title":"Pharmacokinetic profile of bitopertin, a selective GlyT1 inhibitor, in the rat","year":2023,"lang":"en","type":"article","venue":"Naunyn-Schmiedeberg s Archives of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier de l’Université de Montréal; McGill University Health Centre; Université de Montréal; Montreal Neurological Institute and Hospital","funders":"","keywords":"Pharmacokinetics; Cmax; Pharmacology; Chemistry; Oral administration; Volume of distribution; Tolerability; Bioavailability; High-performance liquid chromatography; Chromatography; Medicine; Adverse effect","score_opus":0.01145808532642264,"score_gpt":0.2836241111164504,"score_spread":0.2721660257900278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315702519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994412,0.00069085247,0.00020881933,0.0004928198,0.0005281906,0.00062794314,0.000024050541,0.000019863506,0.0029954405],"genre_scores_gemma":[0.9974954,0.0006164569,0.00046993396,0.00040512462,0.0003343227,0.00015484367,0.00007229041,0.000030048212,0.00042157684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980616,0.00042164102,0.00049503427,0.0003950731,0.00019768428,0.00042894357],"domain_scores_gemma":[0.9992897,0.00018928453,0.00020404898,0.00019575813,0.000068059395,0.000053153402],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041627433,0.00021805668,0.00032500303,0.00025500017,0.000068834444,0.000006851172,0.00049590616,0.000120252254,0.00017094455],"category_scores_gemma":[0.00006523186,0.0001687075,0.00017365096,0.00052496075,0.0002061902,0.0000063609305,0.0001877564,0.00024344613,0.0000111037625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054301036,0.00017241255,0.00029634507,0.000070863105,0.000091702976,0.000010271383,0.0008652009,0.00077703205,0.98299986,0.000120497396,0.010503872,0.0035489213],"study_design_scores_gemma":[0.0015597437,0.0006137294,0.0004302846,0.000024828334,0.000042716376,0.000008652285,0.00023246679,0.0014646631,0.98349446,0.0002455809,0.011712752,0.00017010237],"about_ca_topic_score_codex":0.00003852525,"about_ca_topic_score_gemma":0.00001718504,"teacher_disagreement_score":0.003378819,"about_ca_system_score_codex":0.000007809913,"about_ca_system_score_gemma":0.00014875783,"threshold_uncertainty_score":0.6879692},"labels":[],"label_agreement":null},{"id":"W4316171149","doi":"10.1016/j.isci.2023.105992","title":"Chrna5 and lynx prototoxins identify acetylcholine super-responder subplate neurons","year":2023,"lang":"en","type":"article","venue":"iScience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health; Canada Research Chairs; University of Toronto","funders":"National Institute on Drug Abuse; Canadian Institutes of Health Research; National Institutes of Health; University of Toronto","keywords":"Nicotinic acetylcholine receptor; Nicotinic agonist; Neuroscience; Biology; Cholinergic; Acetylcholine; Acetylcholine receptor; Transcriptome; Population; Transgene; Receptor; Cell biology; Gene; Genetics; Gene expression; Pharmacology; Medicine","score_opus":0.021302151894470222,"score_gpt":0.29684869101141387,"score_spread":0.27554653911694366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4316171149","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99779165,0.00021049626,0.0009707038,0.00031108496,0.00020972679,0.00024621142,0.000009698345,0.000032452837,0.00021798458],"genre_scores_gemma":[0.9964728,0.00016941156,0.00026427716,0.00023008997,0.000102392,0.0000382895,0.000014611697,0.0000136310155,0.002694551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990114,0.000031148455,0.00012069277,0.0003880821,0.00016379342,0.00028486806],"domain_scores_gemma":[0.9996086,0.000008681421,0.000029769726,0.00022196946,0.000036219528,0.00009476672],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033860796,0.00010362704,0.00008150112,0.00006002374,0.00016784159,0.00007574932,0.00021168203,0.00006802643,0.000060875685],"category_scores_gemma":[0.00008389315,0.00008995496,0.00003816803,0.00025303237,0.000102645,0.000010447903,0.00019489382,0.000068837035,0.00004738245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010911772,0.000008463842,0.00047349252,0.0000056393965,0.0000029707967,0.0000060708535,0.00006764491,0.000047738213,0.9974045,0.000077462515,0.00062932796,0.0012657723],"study_design_scores_gemma":[0.0002670049,0.00014198276,0.0063870046,0.000010143506,0.000004208222,0.000027768196,0.00008407626,0.00089220394,0.9590173,0.00016116936,0.03283095,0.00017622065],"about_ca_topic_score_codex":0.000009450943,"about_ca_topic_score_gemma":0.000009567195,"teacher_disagreement_score":0.03838724,"about_ca_system_score_codex":0.00000403271,"about_ca_system_score_gemma":0.000042800693,"threshold_uncertainty_score":0.36682567},"labels":[],"label_agreement":null},{"id":"W4316511288","doi":"10.1101/2023.01.13.523988","title":"Proofreading Is Too Noisy For Effective Ligand Discrimination","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Proofreading; Ligand (biochemistry); Computer science; Noise (video); Computational biology; Biological system; Artificial intelligence; Biology; Receptor; Genetics; DNA; Polymerase","score_opus":0.016225000116735732,"score_gpt":0.24542708483815343,"score_spread":0.2292020847214177,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4316511288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94170487,0.0008094659,0.0522351,0.00023881643,0.0020066707,0.0023270024,0.0004861957,0.00018370854,0.000008184955],"genre_scores_gemma":[0.99215233,0.00018911969,0.0049492544,0.00020167348,0.0011374567,0.0010588152,0.000007160817,0.0002019279,0.00010226051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976704,0.00007010057,0.0003831222,0.001144525,0.0002390838,0.0004927653],"domain_scores_gemma":[0.99827,0.000043986875,0.0003045088,0.0007612508,0.0004623863,0.000157882],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00057959906,0.00048359967,0.00041772382,0.00015331528,0.00020154771,0.00019082894,0.00038770863,0.00069783616,0.000008207128],"category_scores_gemma":[0.00031874413,0.0005088016,0.0002762534,0.00016717319,0.000050889965,0.000010570205,0.00040432136,0.00029185985,0.00002372649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052293686,0.00004777532,0.0004790537,0.00043657373,0.00018480867,0.000003895424,0.000017521326,0.000044878274,0.99642444,0.00030974517,0.001985154,0.00001384925],"study_design_scores_gemma":[0.00045587076,0.00018158539,0.002707277,0.00025664293,0.0001181844,9.115256e-9,0.000005623587,0.000423327,0.9887061,0.000021371123,0.0065051937,0.00061878667],"about_ca_topic_score_codex":0.000021184786,"about_ca_topic_score_gemma":0.0000029480266,"teacher_disagreement_score":0.050447475,"about_ca_system_score_codex":0.00008193476,"about_ca_system_score_gemma":0.00023478465,"threshold_uncertainty_score":0.99973637},"labels":[],"label_agreement":null},{"id":"W4317433743","doi":"10.26508/lsa.202201791","title":"Human adenylyl cyclase 9 is auto-stimulated by its isoform-specific C-terminal domain","year":2023,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"College of Medicine and Veterinary Medicine, University of Edinburgh; University of Edinburgh","keywords":"Adenylyl cyclase; Gene isoform; Stimulation; Biology; Mutant; Transmembrane domain; Basal (medicine); Gs alpha subunit; Domain (mathematical analysis); Cell biology; Receptor; Biochemistry; Gene; Neuroscience; Endocrinology","score_opus":0.021323152834543436,"score_gpt":0.29025331283271466,"score_spread":0.2689301599981712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317433743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99682325,0.0006548886,0.0009018564,0.0004020529,0.00035551656,0.00017976515,0.000039756913,0.00006763311,0.000575287],"genre_scores_gemma":[0.99204683,0.00025512124,0.00069811894,0.0008882134,0.0002403061,0.0000210525,0.00005935944,0.000024366318,0.0057666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979122,0.000025030144,0.00026536782,0.0007282913,0.00043663086,0.0006324711],"domain_scores_gemma":[0.9991041,0.000006678777,0.000099865494,0.00041398156,0.0001054215,0.00026996474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00051692623,0.00019639752,0.00015665939,0.00006147262,0.0005210362,0.00013845568,0.0006951674,0.00012897086,0.0003527569],"category_scores_gemma":[0.00005059452,0.00018779849,0.00008009065,0.00070535316,0.00025962607,0.000027032864,0.00018209995,0.00012065021,0.00038982037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010154666,0.000020253558,0.000084624524,0.000007644941,0.0000060036023,0.000009785581,0.00008998272,0.00010084523,0.9736324,0.00020621288,0.025364956,0.0004671641],"study_design_scores_gemma":[0.0004061712,0.0002023034,0.0006457983,0.000034671644,0.000003811817,0.00000837467,0.00013033292,0.0018059567,0.88880914,0.00025970032,0.10733741,0.00035635132],"about_ca_topic_score_codex":0.00000432611,"about_ca_topic_score_gemma":0.0000012560159,"teacher_disagreement_score":0.08482326,"about_ca_system_score_codex":0.00002460846,"about_ca_system_score_gemma":0.0001278529,"threshold_uncertainty_score":0.76581997},"labels":[],"label_agreement":null},{"id":"W4317816982","doi":"10.3390/ijms24032135","title":"New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Saskatchewan","funders":"Canadian Institutes of Health Research; Ministero della Salute; Natural Sciences and Engineering Research Council of Canada; Università di Pisa; GlaxoSmithKline","keywords":"Allosteric regulation; Cannabinoid receptor; Chemistry; Agonist; Cannabinoid; G protein-coupled receptor; Ligand (biochemistry); Receptor; Allosteric modulator; Cannabinoid receptor type 2; Pharmacology; Stereochemistry; Neuroscience; Biochemistry; Biology","score_opus":0.013196649944741587,"score_gpt":0.28104910508780473,"score_spread":0.26785245514306316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317816982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933587,0.0010754117,0.0030998597,0.00046898605,0.0017642968,0.00003554952,0.0000010414958,0.0000041368517,0.00019204302],"genre_scores_gemma":[0.99596053,0.000378508,0.0029424052,0.0001412257,0.00030997305,6.3567944e-7,0.000007961719,0.000007893107,0.00025087898],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988456,0.000029466732,0.00033071951,0.00015403978,0.0005226753,0.000117516465],"domain_scores_gemma":[0.999152,0.0000091611055,0.00027247955,0.00008853079,0.0003967414,0.00008107058],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025626644,0.00009005846,0.00013107221,0.00022141934,0.00004154132,0.000045061657,0.00060129515,0.00006230775,0.00006631516],"category_scores_gemma":[0.00010704207,0.000072283714,0.000109413224,0.00033962185,0.000067023415,0.00001657633,0.00013033565,0.000061764484,0.0000086230175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038385853,0.000014121181,0.00059173425,0.000003569017,0.00005379581,0.000017352899,0.00024128232,0.0005556873,0.9896849,0.00019860985,0.0009977962,0.0076027974],"study_design_scores_gemma":[0.00024207737,0.0006821109,0.0002617707,0.0000415357,0.000007636193,0.000023849967,0.00021046143,0.000078322315,0.9842143,0.0006905581,0.013457293,0.00009008211],"about_ca_topic_score_codex":0.000025854639,"about_ca_topic_score_gemma":0.0000063997463,"teacher_disagreement_score":0.012459496,"about_ca_system_score_codex":0.000013488127,"about_ca_system_score_gemma":0.00030451198,"threshold_uncertainty_score":0.29476443},"labels":[],"label_agreement":null},{"id":"W4317926744","doi":"10.26443/mjm.v10i2.458","title":"β-Adrenergic receptor signaling in cardiac function and heart failure","year":2020,"lang":"en","type":"article","venue":"McGill Journal of Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"University of North Carolina at Chapel Hill","keywords":"Medicine; Heart failure; Adrenergic; Adrenergic receptor; Cardiac function curve; Function (biology); Receptor; β2 adrenergic receptor; Internal medicine; Cardiology; Cell biology; Agonist; Biology","score_opus":0.014878895926861231,"score_gpt":0.23209938053126328,"score_spread":0.21722048460440205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317926744","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98717195,0.0035089229,0.0010158314,0.0077052913,0.00043224607,0.00006896413,0.0000044678304,0.000003718624,0.000088629364],"genre_scores_gemma":[0.99513584,0.00032352775,0.0010392097,0.0023996453,0.0010656499,9.043541e-7,0.000007862994,0.000012634404,0.000014725301],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99919605,0.000076222466,0.0003082041,0.00013560458,0.00016679127,0.00011714697],"domain_scores_gemma":[0.9995782,0.0000137085835,0.00012651774,0.000055628796,0.00008173624,0.00014423546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042868988,0.000097381206,0.00026013324,0.000052128413,0.00004005296,0.0000045664415,0.0000640733,0.00008378471,0.00012699711],"category_scores_gemma":[0.00011992686,0.00007416993,0.000060656526,0.00009311199,0.00002927954,0.0000056765225,0.000024910165,0.00014989563,0.0000014136837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012837247,0.0000074108125,0.00061752734,0.0000142496065,0.00003106235,0.0000027392352,0.00003733932,0.00014760856,0.9920976,0.000060325194,0.0057615405,0.0010942352],"study_design_scores_gemma":[0.0026169566,0.0031978097,0.0006674187,0.00020579794,0.00006843997,0.000047730497,0.0008739694,0.00005120613,0.6396053,0.0001818058,0.3522896,0.00019396652],"about_ca_topic_score_codex":0.000005234277,"about_ca_topic_score_gemma":0.0000010618811,"teacher_disagreement_score":0.35249227,"about_ca_system_score_codex":0.000008645885,"about_ca_system_score_gemma":0.000016556995,"threshold_uncertainty_score":0.3024562},"labels":[],"label_agreement":null},{"id":"W4317937195","doi":"10.26434/chemrxiv-2023-mbr7t","title":"A mechanistic model explaining ligand affinity for, and partial agonism of, cannabinoid receptor 1","year":2023,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; Compute Canada","keywords":"Cannabinoid; Cannabinoid receptor; Agonism; Chemistry; In silico; Ligand (biochemistry); Receptor; Intrinsic activity; Molecular model; Mechanism (biology); Mechanism of action; G protein-coupled receptor; Computational biology; Stereochemistry; Biology; Biochemistry; Agonist; In vitro","score_opus":0.0406030985758955,"score_gpt":0.27541399964811236,"score_spread":0.23481090107221686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317937195","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87743545,0.0005723196,0.12043311,0.000102724574,0.00072231155,0.0004941169,0.0001135051,0.000041388776,0.0000851068],"genre_scores_gemma":[0.98552585,0.0004980105,0.011800908,0.000052175787,0.00045405613,0.0002809861,0.0005283494,0.00008800136,0.00077164266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984348,0.000027544058,0.00037639905,0.0006954645,0.00013930148,0.00032649375],"domain_scores_gemma":[0.999036,0.000025525484,0.0002490501,0.0004182817,0.0001419264,0.00012918106],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004082184,0.00031355774,0.00041329843,0.000057786918,0.000105721156,0.000044022778,0.00025099504,0.0005598362,0.000012389935],"category_scores_gemma":[0.0002283015,0.0003289802,0.00019795565,0.000042825668,0.00006870522,0.000002463112,0.00055641215,0.00021793907,0.0000023375308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009290654,0.000026938602,0.0000139154845,0.00032970216,0.00009341474,8.5964257e-7,0.00020079457,0.0013000444,0.99524957,0.001214377,0.0011912733,0.00028621696],"study_design_scores_gemma":[0.00040816545,0.0001392565,0.0000032515047,0.00011066111,0.00006862472,0.0000015038829,0.00007621536,0.012978097,0.9776502,0.0074353307,0.000772063,0.00035661532],"about_ca_topic_score_codex":0.000027953367,"about_ca_topic_score_gemma":0.000008673626,"teacher_disagreement_score":0.1086322,"about_ca_system_score_codex":0.000016398815,"about_ca_system_score_gemma":0.00021812497,"threshold_uncertainty_score":0.9999162},"labels":[],"label_agreement":null},{"id":"W4319263819","doi":"10.1101/2023.02.05.527200","title":"Development of a multifunctional toolkit of intrabody-based biosensors recognizing the V5 peptide tag: highlighting applications with G protein-coupled receptors","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Computational biology; Peptide; Traceability; Computer science; Intracellular; Protein tag; Biology; Cell biology; Biochemistry; Software engineering; Gene; Fusion protein","score_opus":0.01690395155936979,"score_gpt":0.21390547868498969,"score_spread":0.19700152712561989,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319263819","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9477553,0.00019519929,0.049977474,0.00009738287,0.0003098,0.0014800534,0.000092177725,0.00008888204,0.0000037746797],"genre_scores_gemma":[0.887945,0.000036426605,0.11071083,0.00003147407,0.00028312186,0.000834571,0.000009156903,0.000129292,0.000020139436],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99733365,0.000105632105,0.00084684254,0.00087501743,0.00044243367,0.0003964183],"domain_scores_gemma":[0.99721444,0.000055792323,0.0009362879,0.000881679,0.0007906924,0.00012110804],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000861093,0.00046411104,0.00048126848,0.00018496062,0.00024099248,0.000054214146,0.00052698294,0.00042727625,0.00003558555],"category_scores_gemma":[0.00016636346,0.0003763288,0.00017419443,0.000447516,0.00015708826,0.0000075389707,0.00029074313,0.00038241054,0.000009848523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000102351085,0.000097368575,0.00048582093,0.00037638738,0.00028223358,0.0000013609978,0.000019145038,0.0008436508,0.9975877,0.00016016293,0.000030636853,0.000013226422],"study_design_scores_gemma":[0.00044107914,0.00008192792,0.0012411769,0.00058654847,0.000072696865,1.5148034e-8,0.00003165121,0.00050156325,0.9913619,0.000001473307,0.005212869,0.000467075],"about_ca_topic_score_codex":0.000031652024,"about_ca_topic_score_gemma":0.000014185662,"teacher_disagreement_score":0.06073336,"about_ca_system_score_codex":0.000067872155,"about_ca_system_score_gemma":0.0011823872,"threshold_uncertainty_score":0.99986887},"labels":[],"label_agreement":null},{"id":"W4319334860","doi":"10.1111/bcpt.13841","title":"The adhesion G protein‐coupled receptor GPR56/<i>ADGRG1</i> in cytotoxic lymphocytes","year":2023,"lang":"en","type":"review","venue":"Basic & Clinical Pharmacology & Toxicology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Deutsche Forschungsgemeinschaft","keywords":"Cytotoxic T cell; Cell biology; Effector; Biology; Receptor; Haematopoiesis; Molecular biology; In vitro; Biochemistry; Stem cell","score_opus":0.08641892576123104,"score_gpt":0.4172179063064031,"score_spread":0.33079898054517204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319334860","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016053092,0.97037715,0.00004364753,0.00047182888,0.008379916,0.004319392,0.00006950709,0.00012762069,0.00015782662],"genre_scores_gemma":[0.00031426133,0.9883391,0.0001951894,0.0012556973,0.0037119368,0.0024848788,0.00033473052,0.00024198652,0.003122197],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99005806,0.0033317502,0.0029838507,0.0018861068,0.0003059108,0.0014343094],"domain_scores_gemma":[0.99534863,0.001976766,0.0012361325,0.000911106,0.00014921147,0.00037814034],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004410958,0.0009839619,0.0027775627,0.00023658175,0.00040781897,0.00005946777,0.00167544,0.002991127,0.000665538],"category_scores_gemma":[0.0012725035,0.000720554,0.0014227927,0.00059651776,0.0007382024,0.000009449699,0.0009686803,0.0016678536,0.0010586178],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012366817,0.0014080957,0.000046868205,0.0034761075,0.0022389502,0.0002697811,0.000028454424,0.000016949267,0.22443977,0.000340743,0.08412592,0.6823717],"study_design_scores_gemma":[0.0019646115,0.0013911481,0.0000075187804,0.0008851675,0.0004733033,0.000035192283,0.00001938567,0.00004403013,0.0054244576,0.0001354602,0.988876,0.00074373564],"about_ca_topic_score_codex":0.00001757666,"about_ca_topic_score_gemma":0.00010325434,"teacher_disagreement_score":0.90475005,"about_ca_system_score_codex":0.00023087767,"about_ca_system_score_gemma":0.0017396504,"threshold_uncertainty_score":0.9997192},"labels":[],"label_agreement":null},{"id":"W4319880606","doi":"10.1016/j.bpj.2022.11.2721","title":"Dissecting diffusion and oligomerization dynamics of GPCRs in live cells using single-particle tracking","year":2023,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Tracking (education); Diffusion; Dynamics (music); Particle (ecology); Biophysics; Chemistry; Physics; Biology; Thermodynamics","score_opus":0.01767999636642161,"score_gpt":0.2528581049351932,"score_spread":0.23517810856877155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319880606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99602723,0.000019144369,0.003736394,0.000016701413,0.00014594445,0.00003964825,0.000002421191,0.000004514485,0.000007999992],"genre_scores_gemma":[0.9993224,0.000057464425,0.00039515982,0.0000071820114,0.00018363785,4.8222796e-7,0.00000786739,0.000012142556,0.00001366139],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99941707,0.00003105191,0.0001848687,0.000120576566,0.00009565194,0.00015076838],"domain_scores_gemma":[0.9997365,0.000013094256,0.00009635933,0.000051076466,0.00005071824,0.000052245232],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012058279,0.00007059508,0.000104470244,0.000041175917,0.0000689173,0.000030157142,0.000048797745,0.0000567651,0.0000056252497],"category_scores_gemma":[0.000038325565,0.00006487585,0.000045481116,0.00015262686,0.000026740281,0.000008129305,0.00004729993,0.000077090815,8.490625e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002237129,0.00004580027,0.0014696092,0.000009572081,0.0000068824597,0.0000041958488,0.000149089,0.0010143596,0.9949474,0.00005899224,5.668019e-7,0.0022711882],"study_design_scores_gemma":[0.00020918145,0.00012754124,0.0014200059,0.000045006433,0.0000067844717,0.000009524578,0.0005302892,0.07150963,0.9259625,0.000102117134,0.0000032112848,0.000074191084],"about_ca_topic_score_codex":0.000010943207,"about_ca_topic_score_gemma":0.0000054383095,"teacher_disagreement_score":0.07049526,"about_ca_system_score_codex":0.000016840411,"about_ca_system_score_gemma":0.000010945378,"threshold_uncertainty_score":0.26455605},"labels":[],"label_agreement":null},{"id":"W4319917295","doi":"10.1016/j.bpj.2022.11.1440","title":"Ancestral acetylcholine receptor beta-subunit forms homopentamers that prime before opening spontaneously","year":2023,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Prime (order theory); BETA (programming language); Protein subunit; Acetylcholine receptor; Receptor; Chemistry; Cell biology; Biophysics; Computational biology; Biology; Biochemistry; Mathematics; Combinatorics; Computer science; Gene","score_opus":0.022328261162151947,"score_gpt":0.26955899543824074,"score_spread":0.2472307342760888,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4319917295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9973507,0.000050435905,0.0012284891,0.00035041847,0.00055838784,0.00015557968,0.000027836242,0.00003720812,0.00024096819],"genre_scores_gemma":[0.99506617,0.0002277641,0.0015004465,0.00018911724,0.001533279,0.000010775536,0.0002045227,0.00005156856,0.001216369],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839544,0.000052870608,0.0002941065,0.00034770957,0.0003498284,0.00056001224],"domain_scores_gemma":[0.99920744,0.000011432585,0.00017767368,0.00023736726,0.00008022251,0.00028584275],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003134386,0.0002536129,0.00027493807,0.00007454537,0.00030905567,0.00016649351,0.00043076446,0.00016154563,0.00029493787],"category_scores_gemma":[0.000025846797,0.00019844733,0.0002952733,0.00022216947,0.00007854492,0.000026153692,0.00016930883,0.00035401172,0.00018980524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011770305,0.000045752462,0.00023813562,0.000006332164,0.00008649168,0.00007301476,0.00008464964,0.0000572408,0.9877212,0.0001189597,0.0016382284,0.009812262],"study_design_scores_gemma":[0.0007771293,0.0007683985,0.0006130132,0.000049713322,0.0000359703,0.0004370257,0.0003948185,0.00020014147,0.9682828,0.00011581303,0.027965533,0.00035962046],"about_ca_topic_score_codex":0.000009007958,"about_ca_topic_score_gemma":0.000006667185,"teacher_disagreement_score":0.026327305,"about_ca_system_score_codex":0.00003484235,"about_ca_system_score_gemma":0.00008394043,"threshold_uncertainty_score":0.80924475},"labels":[],"label_agreement":null},{"id":"W4320484912","doi":"10.1063/5.0139510","title":"Fractionation factors reveal hidden frustration in an ancient allosteric module","year":2023,"lang":"en","type":"article","venue":"The Journal of Chemical Physics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Allosteric regulation; Hydrogen bond; Frustration; Cyclic nucleotide; Cyclic guanosine monophosphate; Chemistry; Nucleotide; Biophysics; Allosteric enzyme; Stereochemistry; Crystallography; Biochemistry; Biology; Enzyme; Molecule; Neuroscience; Gene","score_opus":0.025375682861824667,"score_gpt":0.27417280317549664,"score_spread":0.24879712031367196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320484912","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99880326,0.00002692435,0.0008948607,0.00009120603,0.00011193069,0.00003813461,0.0000018883665,0.0000030725528,0.000028735523],"genre_scores_gemma":[0.99930644,0.000021461232,0.00015089831,0.000055606048,0.0003955465,7.2122657e-7,0.00003843366,0.000007618645,0.000023260347],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99946976,0.00004158824,0.00017366276,0.0000633681,0.00015994134,0.00009165864],"domain_scores_gemma":[0.99965763,0.00001528361,0.00012899988,0.00008423112,0.00007798075,0.000035875353],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024060292,0.00005893138,0.00007572222,0.000018664607,0.000022994182,0.000011768487,0.00011666598,0.00005451209,0.0000085762385],"category_scores_gemma":[0.00002963397,0.00004147333,0.000046023473,0.00011317805,0.00001494267,0.00001465282,0.00002221238,0.00011168746,0.0000022970798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037551203,0.000031215503,0.00022776815,0.000002509403,0.000007018723,4.4460288e-7,0.00011357877,0.0006306424,0.997344,0.000027373035,0.00039102492,0.0011868556],"study_design_scores_gemma":[0.0001642304,0.0001098254,0.0012205954,0.000008056478,0.000007807324,0.0000034917311,0.00013601387,0.00054271356,0.99503577,0.0025866625,0.00013059063,0.000054217922],"about_ca_topic_score_codex":0.0000028705047,"about_ca_topic_score_gemma":6.5781006e-7,"teacher_disagreement_score":0.0025592896,"about_ca_system_score_codex":0.000019420135,"about_ca_system_score_gemma":0.000028439841,"threshold_uncertainty_score":0.16912332},"labels":[],"label_agreement":null},{"id":"W4321019824","doi":"10.1016/j.jbc.2023.103030","title":"Coevolutionary signals in metabotropic glutamate receptors capture residue contacts and long-range functional interactions","year":2023,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of General Medical Sciences; National Institute on Aging; National Institutes of Health; Welch Foundation","keywords":"Functional divergence; Metabotropic glutamate receptor; Biology; Computational biology; Glutamate receptor; Genetics; Receptor; Gene","score_opus":0.025505628473929468,"score_gpt":0.2579908549796428,"score_spread":0.23248522650571335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321019824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969034,0.0018762541,0.00038736776,0.0002752925,0.0003204909,0.00005408433,0.000014290568,0.000010099018,0.00015870789],"genre_scores_gemma":[0.9976115,0.0010077158,0.00018990927,0.000104155355,0.00046255713,0.0000057996126,0.00006437693,0.000009781944,0.0005441871],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99897814,0.0000704757,0.0003869045,0.0002138893,0.0001416676,0.00020894874],"domain_scores_gemma":[0.99940556,0.000059876897,0.0002057611,0.00009266616,0.00011841338,0.000117690324],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034328495,0.00014576942,0.00024230797,0.0000535514,0.00006202755,0.00002034901,0.00011784384,0.00023098491,0.0004260326],"category_scores_gemma":[0.00023067136,0.00010973482,0.0001303582,0.00015202267,0.00006742319,0.00001071657,0.00007629665,0.00028740833,0.000006104975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023675231,0.000050608123,0.017398614,0.000017666849,0.000053922962,0.000058324833,0.000014709114,0.0002340567,0.97967666,0.000008610916,0.0020251477,0.00022489614],"study_design_scores_gemma":[0.0016687901,0.00050325267,0.110912636,0.00015003195,0.000043731183,0.0007591777,0.0005430834,0.00012315605,0.86865187,0.00074138906,0.01546385,0.00043903248],"about_ca_topic_score_codex":0.00000471484,"about_ca_topic_score_gemma":0.0000042253796,"teacher_disagreement_score":0.11102482,"about_ca_system_score_codex":0.000029256675,"about_ca_system_score_gemma":0.00005807773,"threshold_uncertainty_score":0.46647584},"labels":[],"label_agreement":null},{"id":"W4321083453","doi":"10.1101/2023.02.14.528498","title":"Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Genève; University of Toronto; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Liraglutide; Receptor; Glucagon-like peptide 1 receptor; G protein-coupled receptor; Fluorescence; Chemistry; Derivative (finance); HEK 293 cells; Förster resonance energy transfer; Biophysics; Cell biology; Biology; Biochemistry; Endocrinology; Physics; Type 2 diabetes; Agonist","score_opus":0.02596998865305265,"score_gpt":0.252898774034841,"score_spread":0.22692878538178837,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321083453","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8977627,0.00016360472,0.100257434,0.00014655753,0.00039977033,0.0010017236,0.00013836256,0.00012816781,0.0000016703517],"genre_scores_gemma":[0.9732046,0.000109156594,0.025076738,0.00007708809,0.0010241852,0.0003116818,0.000025487592,0.00015931691,0.000011705105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977749,0.000085645064,0.00044322616,0.0009968996,0.00025460197,0.00044470592],"domain_scores_gemma":[0.9984641,0.00006299273,0.00036995622,0.0005198999,0.00041521832,0.00016785326],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006328179,0.00043172337,0.00044455373,0.00013006866,0.00030041795,0.00033586568,0.00021080174,0.00065654307,0.000010281763],"category_scores_gemma":[0.00030065107,0.00043553681,0.00010909154,0.00012863141,0.000082631355,0.000027038002,0.00022711101,0.0003112107,0.0000036029298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021460108,0.000038388895,0.00032734027,0.00019301713,0.0001506623,0.0000015074272,0.000004527979,0.00028562883,0.9965245,0.0021201267,0.00013302396,0.0000066741804],"study_design_scores_gemma":[0.0011241671,0.00038829786,0.0026537853,0.00037407177,0.000080738864,1.0257912e-8,0.0000090853655,0.0005577822,0.99232924,0.000011033269,0.0018733498,0.0005984134],"about_ca_topic_score_codex":0.000054552696,"about_ca_topic_score_gemma":0.0000060621055,"teacher_disagreement_score":0.075441934,"about_ca_system_score_codex":0.00007454873,"about_ca_system_score_gemma":0.00022021902,"threshold_uncertainty_score":0.9998096},"labels":[],"label_agreement":null},{"id":"W4321375769","doi":"10.3390/nu15041015","title":"Homeostatic Reinforcement Theory Accounts for Sodium Appetitive State- and Taste-Dependent Dopamine Responding","year":2023,"lang":"en","type":"article","venue":"Nutrients","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"National Institutes of Health; Agence Nationale de la Recherche","keywords":"Taste; Dopamine; Neuroscience; Reinforcement; Sodium; Reinforcement learning; Appetite; Psychology; Preference; Chemistry; Endocrinology; Biology; Computer science; Social psychology","score_opus":0.011176965801285153,"score_gpt":0.2581599405856456,"score_spread":0.24698297478436046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321375769","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98045796,0.00023773646,0.01799233,0.000047520905,0.00032006498,0.0005292864,0.000102433245,0.000020344902,0.00029232827],"genre_scores_gemma":[0.99146986,0.0003527243,0.00027905664,0.0001222426,0.00010310745,0.00010692403,0.00027071754,0.000029730387,0.0072656204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99895,0.000040902003,0.00020137982,0.00032180685,0.000174929,0.0003109527],"domain_scores_gemma":[0.99954164,0.000042605625,0.00008343172,0.00016678542,0.00008530165,0.000080224236],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005463828,0.00014158244,0.00013559179,0.0001232255,0.00013088579,0.00004495306,0.00010977089,0.000070336515,0.00004976978],"category_scores_gemma":[0.00011367773,0.00013124383,0.00004804161,0.00012789074,0.00003193591,0.0000068196196,0.00012675715,0.00004872737,0.00003122271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013734963,0.000055820426,0.0006086484,0.00013246827,0.00013561799,0.0000100485795,0.0005424053,0.00019137234,0.98531777,0.0030258591,0.0014863113,0.0071202023],"study_design_scores_gemma":[0.0028143022,0.0007848317,0.0003388874,0.00008679433,0.000029352927,0.000005007346,0.0012690236,0.00038468544,0.96098405,0.0041950294,0.02877135,0.000336691],"about_ca_topic_score_codex":0.0000026806076,"about_ca_topic_score_gemma":0.0000013982514,"teacher_disagreement_score":0.027285038,"about_ca_system_score_codex":0.000019645695,"about_ca_system_score_gemma":0.000031220174,"threshold_uncertainty_score":0.5351968},"labels":[],"label_agreement":null},{"id":"W4322768991","doi":"10.3389/fpsyt.2023.1159000","title":"Editorial: Precision psychiatry from a pharmacogenetics perspective","year":2023,"lang":"en","type":"editorial","venue":"Frontiers in Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Alberta; NOSM University; Women and Children’s Health Research Institute","funders":"","keywords":"Pharmacogenetics; Precision medicine; Perspective (graphical); Psychiatry; Medicine; Psychology; Computer science; Biology; Genetics; Genotype; Artificial intelligence","score_opus":0.0045600039445922525,"score_gpt":0.27074538448030017,"score_spread":0.2661853805357079,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4322768991","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006647662,0.0148269385,0.004409765,0.00016123998,0.97806686,0.00046421262,0.0010077958,0.00008160951,0.00031681976],"genre_scores_gemma":[0.000036160684,0.0045383098,0.02918591,0.000067531546,0.9626954,0.00010142885,0.0022436837,0.0002891409,0.00084241235],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99569756,0.00021957447,0.0007473705,0.001587958,0.0010397705,0.0007077918],"domain_scores_gemma":[0.99806786,0.0000774832,0.00040218083,0.00089263386,0.00034366627,0.00021617753],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00054688327,0.00072544906,0.00073020416,0.00033176356,0.00014118591,0.00011062562,0.0009990004,0.0027453399,0.00007135611],"category_scores_gemma":[0.000502483,0.00078029267,0.00045489086,0.0003919997,0.000083409795,0.000008757784,0.00028909187,0.0013272552,0.00005572593],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005019006,0.00015189165,0.0005054425,0.00004922744,0.0003453889,0.0000020096638,0.00008912433,0.00007720751,0.0018416027,0.000020068805,0.99593544,0.00048071885],"study_design_scores_gemma":[0.0018920541,0.00031817282,0.000022414943,0.00029558467,0.00015535197,2.981955e-7,0.0010791445,0.000060000988,0.00044737614,0.011027189,0.9838104,0.00089197647],"about_ca_topic_score_codex":0.0002864343,"about_ca_topic_score_gemma":0.0002524067,"teacher_disagreement_score":0.024776144,"about_ca_system_score_codex":0.00017539736,"about_ca_system_score_gemma":0.0014610657,"threshold_uncertainty_score":0.9994648},"labels":[],"label_agreement":null},{"id":"W4327900067","doi":"10.7554/elife.83529","title":"Context-dependent requirement of G protein coupling for Latrophilin-2 in target selection of hippocampal axons","year":2023,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"National Institute of Neurological Disorders and Stroke; National Eye Institute; National Institute of Mental Health; National Institutes of Health; Hope for Depression Research Foundation","keywords":"Subiculum; Agonist; Cell biology; Hippocampal formation; Context (archaeology); Neuroscience; Receptor; Biology; Biophysics; G protein-coupled receptor; Intracellular; Chemistry; Signal transduction; Biochemistry","score_opus":0.02142937623317783,"score_gpt":0.27177096871534645,"score_spread":0.25034159248216864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4327900067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992067,0.00028411433,0.0070236423,0.000035584973,0.00009547622,0.00044227162,0.000021754153,0.00000854847,0.000021626322],"genre_scores_gemma":[0.99785143,0.00004259134,0.0017032888,0.000016158328,0.000099874225,0.00007437817,0.00005539795,0.000013805167,0.00014306574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992452,0.0000139778585,0.0002725457,0.00017403747,0.00014161163,0.0001525952],"domain_scores_gemma":[0.99966496,0.000007839449,0.00009735552,0.000103638245,0.00009915993,0.000027040975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043265888,0.000074207754,0.0001505423,0.00005709916,0.000025048726,0.0000034574005,0.00007232293,0.000081867875,0.000029428433],"category_scores_gemma":[0.000076581935,0.00007401038,0.000082667444,0.00009735029,0.000014991221,0.000002140607,0.000033724165,0.00003903744,0.0000016403736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000103977574,0.000034462042,0.0005689886,0.00004884092,0.000029846478,2.941967e-7,0.000038329385,0.0035058009,0.99473095,0.00026004098,0.000089558154,0.00058892294],"study_design_scores_gemma":[0.0005619814,0.00037363503,0.00012061001,0.000034201697,0.000005999679,3.3820908e-7,0.00014563162,0.0033250994,0.99341834,0.0001520872,0.0017880955,0.00007396379],"about_ca_topic_score_codex":0.000028005337,"about_ca_topic_score_gemma":0.000028188111,"teacher_disagreement_score":0.0057844585,"about_ca_system_score_codex":0.000012690319,"about_ca_system_score_gemma":0.00005797017,"threshold_uncertainty_score":0.30180556},"labels":[],"label_agreement":null},{"id":"W4360872645","doi":"10.3389/fcvm.2023.1177727","title":"Editorial: Receptors in cardiovascular diseases: Mechanisms, diagnosis, and treatment","year":2023,"lang":"en","type":"editorial","venue":"Frontiers in Cardiovascular Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Intensive care medicine; Cardiology; Internal medicine","score_opus":0.007120042479676269,"score_gpt":0.23246661322155676,"score_spread":0.2253465707418805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4360872645","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000086033164,0.2381359,0.0036589827,0.000038655,0.75696373,0.0008875902,0.00014486151,0.00004993075,0.00003433223],"genre_scores_gemma":[0.00017606262,0.11638385,0.00084240414,0.000017305827,0.87843156,0.0010142642,0.0025982144,0.00026296312,0.0002733733],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9935481,0.000693535,0.0008864434,0.0019847194,0.0019782507,0.00090894004],"domain_scores_gemma":[0.99739116,0.00017341373,0.00017430341,0.0016902942,0.0002073348,0.00036348717],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0025580644,0.0009843234,0.0030373835,0.00065273856,0.00011042168,0.000049691902,0.00052590645,0.0020389794,0.00002270976],"category_scores_gemma":[0.0019800884,0.000884742,0.0016222092,0.00056637527,0.00021774325,0.000014054523,0.00025867723,0.0007215151,0.0000072329394],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012403393,0.00007096835,0.0004303172,0.00018078856,0.004508943,0.00013056144,0.00012594077,0.0006032421,0.00009492204,0.0000036932586,0.97261965,0.021106938],"study_design_scores_gemma":[0.004441311,0.0007436987,0.000045557572,0.00061879394,0.0014343741,0.0000025416089,0.00047245718,0.000025233134,0.00043678176,0.00028436186,0.9906622,0.00083265355],"about_ca_topic_score_codex":0.0013479784,"about_ca_topic_score_gemma":0.00012924951,"teacher_disagreement_score":0.12175205,"about_ca_system_score_codex":0.00049959694,"about_ca_system_score_gemma":0.00038706884,"threshold_uncertainty_score":0.9993603},"labels":[],"label_agreement":null},{"id":"W4362457718","doi":"10.1038/s41594-023-00957-1","title":"Mapping the conformational landscape of the stimulatory heterotrimeric G protein","year":2023,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Heterotrimeric G protein; G protein; Allosteric regulation; Chemistry; Biophysics; G protein-coupled receptor; Lipid bilayer; G alpha subunit; Protein subunit; Helix (gastropod); Biochemistry; Signal transduction; Receptor; Biology; Membrane","score_opus":0.007006666051088699,"score_gpt":0.2614743101595037,"score_spread":0.254467644108415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362457718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99652886,0.001031169,0.0009607341,0.0004683408,0.00042461554,0.00037099922,0.00003092078,0.000016905797,0.00016743799],"genre_scores_gemma":[0.99874437,0.0000078286475,0.0002424095,0.00058142346,0.00012844584,0.000020333482,0.00015717199,0.0000138598125,0.00010415556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990364,0.00013752052,0.00022095331,0.00022358577,0.00014384337,0.00023772373],"domain_scores_gemma":[0.99936944,0.000012096288,0.00015271925,0.00033898148,0.00009644494,0.000030312089],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018108373,0.00015267199,0.00014194392,0.00005119793,0.00014592403,0.000012176582,0.00042319944,0.00034685852,0.00005019487],"category_scores_gemma":[0.00010800206,0.00008272611,0.00016865098,0.00028568867,0.00012810495,0.000003024502,0.00020532936,0.0003076827,0.000004466994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018828747,0.0000014946826,0.000316725,0.000010601285,0.000054729917,6.6748714e-7,0.000037947455,0.00035353765,0.9947701,0.0033213133,0.00026691388,0.0008471128],"study_design_scores_gemma":[0.00037687804,0.00010189576,0.005099822,0.000015387744,0.000009848029,0.000020856578,0.00009803348,0.000820061,0.98314136,0.0027074632,0.0074390406,0.00016934419],"about_ca_topic_score_codex":0.0000050382537,"about_ca_topic_score_gemma":0.0000012742685,"teacher_disagreement_score":0.011628758,"about_ca_system_score_codex":0.0000060896386,"about_ca_system_score_gemma":0.00006104495,"threshold_uncertainty_score":0.3373473},"labels":[],"label_agreement":null},{"id":"W4362508755","doi":"10.1101/2023.04.01.535208","title":"β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Queen's University Belfast; Biotechnology and Biological Sciences Research Council; LEO Fondet; Department for the Economy; Queen's University; Wellcome Trust","keywords":"Endosome; Arrestin; Chemistry; Vasopressin receptor; Vasopressin; Receptor; Endocrinology; Internal medicine; Cell biology; G protein-coupled receptor; Biology; Biochemistry; Medicine; Antagonist","score_opus":0.014941094137444821,"score_gpt":0.2201737536028718,"score_spread":0.205232659465427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362508755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931152,0.0012906902,0.0028026393,0.00032069656,0.0011088256,0.0010657087,0.00015075089,0.00013861925,0.0000068997642],"genre_scores_gemma":[0.99685997,0.0003437733,0.0013229215,0.000116191724,0.00075737055,0.00027433666,0.000006634012,0.0001554601,0.00016335667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99742365,0.00020577143,0.0004027835,0.0010646143,0.00043610166,0.00046708295],"domain_scores_gemma":[0.9981947,0.000030746018,0.00036371005,0.000939825,0.00028833738,0.00018271393],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006048297,0.00048865005,0.0003212476,0.0000807948,0.0002602922,0.00027056978,0.00052804855,0.0006607183,0.000059938633],"category_scores_gemma":[0.00030333988,0.00042059316,0.00010251777,0.0001805219,0.00008797564,0.000012240051,0.0007863521,0.0006140624,0.00004027028],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006284221,0.00004887184,0.00050565304,0.00009081357,0.00013001508,0.0000042606816,0.0000054758316,0.000044610682,0.99722564,0.00011480193,0.0017583743,0.000008666923],"study_design_scores_gemma":[0.0003567585,0.00010606865,0.0016637178,0.00018231844,0.00004239875,3.076506e-8,0.0000074564555,0.000084387255,0.9886316,0.000005631102,0.008421568,0.0004980716],"about_ca_topic_score_codex":0.00008706971,"about_ca_topic_score_gemma":0.00000352465,"teacher_disagreement_score":0.008594021,"about_ca_system_score_codex":0.00006170877,"about_ca_system_score_gemma":0.00031802166,"threshold_uncertainty_score":0.9998246},"labels":[],"label_agreement":null},{"id":"W4362581997","doi":"10.1101/2023.03.30.534775","title":"Medial Prefrontal Cortex Serotonin Input Regulates Cognitive Flexibility in Mice","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Toronto","funders":"National Institute of Mental Health; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Science Foundation","keywords":"Cognitive flexibility; Neuroscience; Optogenetics; Prefrontal cortex; Serotonergic; Dorsal raphe nucleus; Serotonin; Psychology; Flexibility (engineering); Cognition; Medicine; Internal medicine; Receptor","score_opus":0.01784812149181168,"score_gpt":0.24302247919986367,"score_spread":0.225174357708052,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362581997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9951985,0.00077426876,0.00081913604,0.000051049974,0.0014252677,0.001151759,0.00041597217,0.000155397,0.000008632537],"genre_scores_gemma":[0.9967661,0.00028524056,0.001549835,0.00010764986,0.0007612647,0.00031575165,0.000012736162,0.00016957146,0.00003184837],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9964412,0.00024413325,0.00067226496,0.001611809,0.00036312718,0.0006674687],"domain_scores_gemma":[0.998171,0.00005026446,0.0003551915,0.00080898637,0.00037025535,0.0002443485],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0008504926,0.0006206536,0.0006061587,0.00019639883,0.00010665083,0.000120909244,0.0005462624,0.0010988564,0.00006936139],"category_scores_gemma":[0.0004411581,0.0006926476,0.00022304569,0.00028838537,0.00015538736,0.000012044509,0.0008982234,0.0007199444,0.000058064703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000168737,0.0001130084,0.006454935,0.00017133149,0.00012615665,0.000038782135,0.000016236156,0.00008620026,0.9926824,0.000040290364,0.00009975393,0.0000021610908],"study_design_scores_gemma":[0.00072861346,0.00012453839,0.10756072,0.0003853221,0.000054887307,2.3652435e-8,0.0000121592175,0.00027364356,0.88982075,0.000009172439,0.00032152666,0.00070866296],"about_ca_topic_score_codex":0.00015501882,"about_ca_topic_score_gemma":0.000087701155,"teacher_disagreement_score":0.10286167,"about_ca_system_score_codex":0.000121056626,"about_ca_system_score_gemma":0.00065543666,"threshold_uncertainty_score":0.9995525},"labels":[],"label_agreement":null},{"id":"W4362721298","doi":"10.1016/j.jbc.2023.104690","title":"The ubiquitination status of the glucagon receptor determines signal bias","year":2023,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Glucagon receptor; G protein-coupled receptor; Cell biology; Arrestin; Signal transduction; Biology; G protein-coupled receptor kinase; Heterotrimeric G protein; G protein; Chemistry; Glucagon; Endocrinology; Insulin","score_opus":0.0342528582918815,"score_gpt":0.26835430006373046,"score_spread":0.23410144177184894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362721298","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99859095,0.0006051307,0.00010306437,0.00020099207,0.00022221504,0.000049914222,0.000012330877,0.000004818328,0.00021060147],"genre_scores_gemma":[0.99777156,0.001209541,0.00011890851,0.000043109987,0.00045671192,0.0000028974334,0.000014535127,0.0000074802956,0.00037524969],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99896365,0.00008141801,0.0004029991,0.00011971613,0.00019347557,0.00023871647],"domain_scores_gemma":[0.9990201,0.00009990358,0.00044950092,0.00015446536,0.000203762,0.00007224807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00058893574,0.00010538867,0.0001464383,0.0000112340995,0.00012136204,0.000021451106,0.0003431668,0.0001699339,0.00008861816],"category_scores_gemma":[0.0006567051,0.00004952706,0.0002277774,0.00013622882,0.00012474456,0.000003088476,0.00012039634,0.00015440174,0.0000021464994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008345898,0.000018226561,0.0012738276,0.000010732483,0.000027351914,9.554986e-7,0.000014155529,0.00003470477,0.99317485,0.000011174428,0.000972682,0.0043778648],"study_design_scores_gemma":[0.00019848913,0.00018518914,0.0013889304,0.00002487891,0.000008229063,0.000019156316,0.00020659054,0.00002969487,0.978564,0.00020581968,0.019100364,0.00006862082],"about_ca_topic_score_codex":0.0000016934407,"about_ca_topic_score_gemma":5.03163e-7,"teacher_disagreement_score":0.018127684,"about_ca_system_score_codex":0.000016107626,"about_ca_system_score_gemma":0.00008300754,"threshold_uncertainty_score":0.2019655},"labels":[],"label_agreement":null},{"id":"W4364358941","doi":"10.7554/elife.86628","title":"Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution","year":2023,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Genève; University of Toronto; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Receptor; Computational biology; High resolution; Cell biology; Computer science; Biology; Neuroscience; Nanotechnology; Materials science; Remote sensing; Geography; Genetics","score_opus":0.027636492301425074,"score_gpt":0.28783644087333204,"score_spread":0.260199948571907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4364358941","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9541985,0.000036222365,0.045135487,0.00019955567,0.000077469624,0.00026231766,0.000010268101,0.00003289438,0.00004732187],"genre_scores_gemma":[0.99272996,0.000032149448,0.005947057,0.00010769722,0.00044758676,0.00005263693,0.0005131268,0.000022420058,0.00014734424],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930024,0.000023636047,0.00014329309,0.00023782892,0.000118648786,0.00017634901],"domain_scores_gemma":[0.9996771,0.00003172254,0.00006222028,0.00009597422,0.000080640144,0.000052307816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027189264,0.00009519601,0.00011265725,0.000035521287,0.00017007647,0.00006344998,0.000044278906,0.00010396575,0.000011844189],"category_scores_gemma":[0.00011544611,0.00008421002,0.000031045543,0.00006232903,0.000024126366,0.000011640621,0.000027157697,0.000045147946,0.0000030380347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001543172,0.000009534795,0.00010449617,0.000013549321,0.000023533912,2.1234005e-7,0.000030684692,0.00017338934,0.99477994,0.0025006824,0.00058904785,0.0016206021],"study_design_scores_gemma":[0.0010010902,0.00051684096,0.0005262828,0.000034634966,0.0000109772445,7.0510555e-7,0.00012809958,0.00096978707,0.98731375,0.00008265703,0.009268101,0.00014709194],"about_ca_topic_score_codex":0.000015206855,"about_ca_topic_score_gemma":0.000006178712,"teacher_disagreement_score":0.03918843,"about_ca_system_score_codex":0.000011259046,"about_ca_system_score_gemma":0.00002305005,"threshold_uncertainty_score":0.34339848},"labels":[],"label_agreement":null},{"id":"W4365503542","doi":"10.21203/rs.3.rs-2772908/v1","title":"Profiling of basal and ligand-dependent GPCR activities by means of a polyvalent cell-based high-throughput platform","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Profiling (computer programming); G protein-coupled receptor; Computational biology; Throughput; Computer science; Receptor; Chemistry; Nanotechnology; Biology; Cell biology; Biochemistry; Materials science","score_opus":0.04650250640715837,"score_gpt":0.33867163638108105,"score_spread":0.2921691299739227,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4365503542","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908474,0.0020633691,0.005123317,0.00008030371,0.00018745617,0.0007541785,0.0007986005,0.00001665427,0.00012871689],"genre_scores_gemma":[0.9959648,0.0014033086,0.0011604863,0.000008442885,0.00014724664,0.00011228398,0.00060532044,0.00006719615,0.00053086027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974185,0.00016517959,0.00042022136,0.0006551231,0.0008654761,0.0004754514],"domain_scores_gemma":[0.9987628,0.00010717639,0.00020869548,0.0005528526,0.00024135389,0.00012716405],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001226021,0.00026360512,0.00043797784,0.00020168189,0.00010239229,0.00004624613,0.0003507829,0.0004927514,0.00003784393],"category_scores_gemma":[0.000110270616,0.00024769935,0.00017129998,0.00011282691,0.000188969,0.0000050209396,0.0009257015,0.00056631677,0.0000016058333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002395346,0.00013810853,0.00089764746,0.0023929393,0.0000969622,0.000004923458,0.00014826408,0.00092345243,0.99424356,0.00008718235,0.00052156206,0.0003058404],"study_design_scores_gemma":[0.00055841584,0.0007078599,0.000058179317,0.00044871855,0.000018882258,5.694734e-7,0.0010333583,0.00067847286,0.9956694,0.0005020098,0.00010545279,0.0002186509],"about_ca_topic_score_codex":0.00047107428,"about_ca_topic_score_gemma":0.000040394785,"teacher_disagreement_score":0.005117451,"about_ca_system_score_codex":0.000048455255,"about_ca_system_score_gemma":0.0004179599,"threshold_uncertainty_score":0.9999975},"labels":[],"label_agreement":null},{"id":"W4366519497","doi":"10.7554/elife.83529.sa2","title":"Author response: Context-dependent requirement of G protein coupling for Latrophilin-2 in target selection of hippocampal axons","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"","keywords":"Subiculum; Agonist; Hippocampal formation; Neuroscience; Cell biology; Context (archaeology); Receptor; Intracellular; Chemistry; Biophysics; G protein-coupled receptor; Cleavage (geology); Biology; Signal transduction; Biochemistry; Dentate gyrus","score_opus":0.04728230394962792,"score_gpt":0.33285076606070124,"score_spread":0.28556846211107334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4366519497","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.54294926,0.18836471,0.17856097,0.031107323,0.011122255,0.040104307,0.006868979,0.00027910335,0.00064310787],"genre_scores_gemma":[0.5187251,0.003601542,0.022043206,0.00048480878,0.0013295837,0.0028001808,0.0045132516,0.0004210721,0.44608128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99764246,0.00011041969,0.00097688,0.0005645243,0.0003823071,0.0003234207],"domain_scores_gemma":[0.9985873,0.00004990014,0.00049528235,0.00035169622,0.00045211657,0.00006370226],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002432498,0.00030052927,0.00076985726,0.00016476554,0.00004165706,0.000008931677,0.00025255137,0.00047530988,0.00027859412],"category_scores_gemma":[0.0005979502,0.00028180855,0.00038825008,0.00017812393,0.000036240144,0.000002683698,0.00011284218,0.00019421225,0.0000027305152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00096655835,0.000097648604,0.0000094674,0.002989476,0.00020694286,0.0000013052854,0.000017156766,0.0005075293,0.9433403,0.00011968032,0.05038892,0.0013549916],"study_design_scores_gemma":[0.00074271846,0.0012481344,0.0000055375053,0.002120628,0.00009172225,0.0000018324802,0.00006895595,0.000540324,0.728123,0.00020023143,0.26653412,0.00032278476],"about_ca_topic_score_codex":0.00013671604,"about_ca_topic_score_gemma":0.00020866963,"teacher_disagreement_score":0.44543818,"about_ca_system_score_codex":0.00006430005,"about_ca_system_score_gemma":0.00044703344,"threshold_uncertainty_score":0.9999634},"labels":[],"label_agreement":null},{"id":"W4368373570","doi":"10.1016/j.neuropharm.2023.109572","title":"Enhancement of memory consolidation by an avoidance conditioned stimulus: Modulation by the D3 receptor","year":2023,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Memory consolidation; Neuroscience; Psychology; Stimulus (psychology); Cognitive psychology","score_opus":0.013418053979412072,"score_gpt":0.2839091334241309,"score_spread":0.2704910794447188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4368373570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950203,0.00013377001,0.0034788721,0.00032111054,0.0005741425,0.000274616,0.00008871023,0.000023391043,0.00008510038],"genre_scores_gemma":[0.99690515,0.00028626857,0.00006435053,0.000723881,0.00013305707,0.000062326275,0.00093325047,0.000019550444,0.00087216863],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989429,0.0002489779,0.00022677414,0.00028012658,0.00012036463,0.00018084049],"domain_scores_gemma":[0.99951494,0.000043338998,0.00013979082,0.00016847634,0.00008480406,0.000048678314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021644308,0.00010917178,0.000113929054,0.000029156117,0.000114180344,0.000009748417,0.00016142883,0.00008482066,0.0005710653],"category_scores_gemma":[0.000042482086,0.000095335025,0.000038657698,0.00011567085,0.00008008647,0.000007803158,0.000049192233,0.00008221196,0.000038578677],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008020094,0.000057140074,0.000015307382,0.000007695793,0.000021518646,5.1964037e-7,0.00004467539,0.0007093371,0.9466953,0.000017496894,0.05050898,0.0018417875],"study_design_scores_gemma":[0.00056875806,0.00042937326,0.000046286743,0.0000021446117,0.000014190716,0.0000014360293,0.000048578597,0.003184803,0.97724015,0.000027218326,0.018346105,0.00009098498],"about_ca_topic_score_codex":0.000007204284,"about_ca_topic_score_gemma":8.052651e-7,"teacher_disagreement_score":0.032162875,"about_ca_system_score_codex":0.000009666288,"about_ca_system_score_gemma":0.00002820429,"threshold_uncertainty_score":0.62527645},"labels":[],"label_agreement":null},{"id":"W4368405349","doi":"10.3390/biom13050787","title":"Role of Angiotensin II in Cardiovascular Diseases: Introducing Bisartans as a Novel Therapy for Coronavirus 2019","year":2023,"lang":"en","type":"review","venue":"Biomolecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Victoria University","keywords":"Downregulation and upregulation; Angiotensin II; Angiotensin-converting enzyme 2; Medicine; Oxidative stress; Renin–angiotensin system; Coronavirus; Angiotensin receptor; Phenotype; Homeostasis; Receptor; Immunology; Coronavirus disease 2019 (COVID-19); Bioinformatics; Disease; Internal medicine; Biology; Gene; Blood pressure; Infectious disease (medical specialty)","score_opus":0.033676929894979,"score_gpt":0.3161959387547155,"score_spread":0.2825190088597365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4368405349","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012235739,0.99556327,0.0011056676,0.000009377626,0.00022157271,0.0012047685,0.00063764985,0.000020100733,0.00001403586],"genre_scores_gemma":[0.0003219838,0.99656945,0.00096726965,0.000025907315,0.00041316173,0.00020192128,0.00121548,0.0001378403,0.00014700156],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99797094,0.000095244184,0.0005717058,0.00077577063,0.0002166538,0.00036966312],"domain_scores_gemma":[0.998855,0.00003405908,0.00023310048,0.00069383456,0.000100751255,0.00008326965],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00034028458,0.00042411694,0.0013674595,0.00020580352,0.00007026606,0.000023454899,0.00035121787,0.0004251768,0.0000104912],"category_scores_gemma":[0.00011671462,0.00036798298,0.0015315902,0.000293196,0.00007505806,0.000003183118,0.00016980886,0.000096866235,0.000008783448],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000080759404,0.00019753014,0.0000027029987,0.0015969448,0.0016819359,0.000006121534,0.000054111613,0.000042871605,0.3012748,0.0002870537,0.0004153057,0.69435984],"study_design_scores_gemma":[0.0006513366,0.00043702792,0.000004143101,0.0017144827,0.00039741784,0.000014538992,0.000050664334,0.00001597706,0.025488928,0.000088527515,0.97064465,0.00049231143],"about_ca_topic_score_codex":0.00024143711,"about_ca_topic_score_gemma":0.00002033521,"teacher_disagreement_score":0.9702293,"about_ca_system_score_codex":0.00003170658,"about_ca_system_score_gemma":0.0003025283,"threshold_uncertainty_score":0.9998772},"labels":[],"label_agreement":null},{"id":"W4375867979","doi":"10.31234/osf.io/46vda","title":"I-frame Interventions Enhance S-frame Interventions","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Psychological intervention; Frame (networking); Spillover effect; Computer science; Psychology; Economics; Telecommunications; Microeconomics","score_opus":0.07322650667368001,"score_gpt":0.3731384061564162,"score_spread":0.29991189948273617,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4375867979","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15059781,0.003669011,0.8348149,0.0009858491,0.0051307147,0.00089617335,0.00028548072,0.00031111488,0.0033089172],"genre_scores_gemma":[0.88198715,0.0014955208,0.015874093,0.00027688258,0.0010336923,0.00046299485,0.0022867662,0.00016266045,0.09642025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99779725,0.000104141,0.00068087416,0.00086025475,0.00019140111,0.00036609898],"domain_scores_gemma":[0.9985217,0.000017725344,0.0002699854,0.00089487544,0.00016606729,0.00012965128],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00043124563,0.00035062726,0.00035852494,0.00013892517,0.000115345814,0.0001463045,0.00063081644,0.000637896,0.0016913561],"category_scores_gemma":[0.00019228437,0.00035259608,0.0016002628,0.00010201828,0.0000625492,0.000003251372,0.0016919753,0.0005393559,0.00035920469],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006864901,0.0007204985,0.00021528614,0.0030478423,0.0015413336,0.0000199654,0.0001862454,0.0024842066,0.90050954,0.0060664,0.07674454,0.008395471],"study_design_scores_gemma":[0.000771063,0.0010036415,0.00047691143,0.006035096,0.00044693807,0.000020953436,0.00065146567,0.0009308865,0.90539676,0.032820318,0.04915821,0.002287772],"about_ca_topic_score_codex":0.00012315586,"about_ca_topic_score_gemma":0.00026039965,"teacher_disagreement_score":0.8189408,"about_ca_system_score_codex":0.000031504216,"about_ca_system_score_gemma":0.0000862896,"threshold_uncertainty_score":0.9998926},"labels":[],"label_agreement":null},{"id":"W4376109416","doi":"10.1101/2023.05.09.539827","title":"Quantitative modeling of EGF receptor ligand discrimination via internalization proofreading","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Internalization; Clathrin; Epidermal growth factor receptor; Ligand (biochemistry); Endosome; Endocytosis; Cell biology; Epidermal growth factor; Receptor; Biology; Chemistry; Biochemistry","score_opus":0.027599994699348686,"score_gpt":0.2561134302597434,"score_spread":0.22851343556039475,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376109416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6089285,0.00050058734,0.38915503,0.000029439596,0.0008539011,0.00037510836,0.00008539452,0.00006805988,0.000003940862],"genre_scores_gemma":[0.98720425,0.00045227405,0.011696138,0.000028598106,0.00034862253,0.00009184347,0.000010354891,0.00014852369,0.000019368148],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977922,0.00011689006,0.0006267285,0.00082207576,0.00031513904,0.00032700362],"domain_scores_gemma":[0.99807894,0.000019492385,0.00051876024,0.00060189684,0.0006663372,0.000114585564],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005755056,0.00039832466,0.00042068795,0.00022933233,0.00010024767,0.00008965351,0.0003869673,0.0005130271,0.000015606074],"category_scores_gemma":[0.00029238942,0.00042911054,0.00018462895,0.00023584982,0.000056760357,0.000017330272,0.00041433016,0.00028740425,0.000015864764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064005006,0.000057470643,0.0005060917,0.00035787758,0.00015624473,0.0000020440393,0.000029974706,0.006530264,0.9914128,0.00081679056,0.00006286808,0.0000035753642],"study_design_scores_gemma":[0.00023609826,0.00015886009,0.0001845129,0.0006356618,0.000072954084,8.050977e-9,0.000015939528,0.055825356,0.94227403,0.00002334721,0.00012514472,0.00044807466],"about_ca_topic_score_codex":0.00007470307,"about_ca_topic_score_gemma":0.000007310209,"teacher_disagreement_score":0.37827575,"about_ca_system_score_codex":0.00007183336,"about_ca_system_score_gemma":0.0002273432,"threshold_uncertainty_score":0.99981606},"labels":[],"label_agreement":null},{"id":"W4376270613","doi":"10.2218/gtopdb/f20/2023.1","title":"Dopamine receptors in GtoPdb v.2023.1","year":2023,"lang":"en","type":"article","venue":"IUPHAR/BPS Guide to Pharmacology CITE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Endogenous agonist; Dopamine; D2-like receptor; Dopamine receptor D3; Dopamine receptor; D1-like receptor; Agonist; Receptor; Dopamine receptor D2; Chemistry; Dopamine receptor D1; Pharmacology; Endocrinology; Internal medicine; Biology; Medicine","score_opus":0.013682081345626814,"score_gpt":0.3247896405082563,"score_spread":0.3111075591626295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376270613","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900681,0.00047683553,0.00068532146,0.0015407762,0.0030429866,0.000580479,0.00006795496,0.00012049914,0.0034170956],"genre_scores_gemma":[0.94301414,0.0012012641,0.0018262437,0.0087960875,0.0021666882,0.0004964284,0.0007619968,0.00013198142,0.04160518],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99769336,0.00016656889,0.00051069545,0.0007065209,0.00018973037,0.0007331425],"domain_scores_gemma":[0.9992408,0.00004439741,0.00009074438,0.0002830315,0.00008590853,0.00025509595],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0007669308,0.00029317007,0.00031151978,0.0003525708,0.00010032663,0.000027602926,0.0004355257,0.00025724026,0.0022262682],"category_scores_gemma":[0.00009210633,0.00030687387,0.0001310301,0.00072434224,0.000056357694,0.000009342134,0.00030740647,0.00022750621,0.001006354],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010271718,0.00003824384,0.0006587256,0.000011187438,0.000048685284,0.00004962589,0.000053792886,0.0007759216,0.7649063,0.000027961461,0.23024519,0.0030816556],"study_design_scores_gemma":[0.0009169552,0.00017388261,0.00027740432,0.00000963695,0.000016785265,0.000009320782,0.00005286219,0.00014634251,0.4818432,0.000026334494,0.5162682,0.00025908233],"about_ca_topic_score_codex":0.000052689946,"about_ca_topic_score_gemma":0.000043432938,"teacher_disagreement_score":0.286023,"about_ca_system_score_codex":0.000053710275,"about_ca_system_score_gemma":0.0000937356,"threshold_uncertainty_score":0.9999383},"labels":[],"label_agreement":null},{"id":"W4376611765","doi":"10.7554/elife.86628.2","title":"Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Genève; University of Toronto; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Liraglutide; Receptor; Glucagon-like peptide 1 receptor; G protein-coupled receptor; Fluorescence; Chemistry; Derivative (finance); HEK 293 cells; Förster resonance energy transfer; Biophysics; Cell biology; Biology; Biochemistry; Endocrinology; Physics; Type 2 diabetes; Agonist","score_opus":0.04813993554704823,"score_gpt":0.30415283425738415,"score_spread":0.25601289871033595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376611765","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.65698797,0.000047897058,0.34167564,0.00021429086,0.00019657283,0.0007140282,0.000035638906,0.000049607163,0.00007839704],"genre_scores_gemma":[0.95916,0.00006777107,0.036564406,0.000078487086,0.0007405929,0.00021101921,0.0025565962,0.00006877347,0.0005523664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859554,0.00004569522,0.0003089639,0.00063423236,0.00016147552,0.00025412036],"domain_scores_gemma":[0.99927145,0.000053385855,0.00018973612,0.0002403302,0.00016754642,0.00007756495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040626535,0.00025345484,0.00029336588,0.000063365864,0.00018376538,0.0001990286,0.00011039844,0.00046758217,0.0000259589],"category_scores_gemma":[0.00013424223,0.00022145388,0.00008724826,0.000036930276,0.000042664018,0.000009421498,0.00019194532,0.00017975853,0.0000016349978],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003212041,0.00002332311,0.00005279298,0.000112825706,0.00011689945,3.1008062e-7,0.000029958659,0.0010233657,0.9914947,0.0048881653,0.00043472007,0.001501707],"study_design_scores_gemma":[0.0012886063,0.00074096164,0.00016569725,0.00022123191,0.000055977103,9.889313e-7,0.00016218342,0.0020181765,0.9912566,0.0015306422,0.0020997697,0.0004591437],"about_ca_topic_score_codex":0.00012489696,"about_ca_topic_score_gemma":0.000041640746,"teacher_disagreement_score":0.30511123,"about_ca_system_score_codex":0.000033185024,"about_ca_system_score_gemma":0.00007349258,"threshold_uncertainty_score":0.9030627},"labels":[],"label_agreement":null},{"id":"W4376872436","doi":"10.1073/pnas.2212795120","title":"Proofreading does not result in more reliable ligand discrimination in receptor signaling due to its inherent stochasticity","year":2023,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Proofreading; Ligand (biochemistry); Computer science; Noise (video); Receptor; Computational biology; Biological system; Algorithm; Artificial intelligence; Biology; Genetics; Polymerase; DNA; Image (mathematics)","score_opus":0.04135422487307043,"score_gpt":0.312289830919724,"score_spread":0.27093560604665357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376872436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976778,0.000029515879,0.0000132824,0.0017678565,0.000033387525,0.00027535704,0.000014346437,0.0000051855354,0.00018329227],"genre_scores_gemma":[0.9987173,0.000017733357,0.00087039074,0.0001125092,0.00006984607,0.000034299974,0.0000011841557,0.000005213887,0.0001715246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986428,0.0000067939495,0.00032678072,0.0002885498,0.00055870035,0.00017637374],"domain_scores_gemma":[0.9995766,0.000032688622,0.00018398518,0.000008551904,0.00016781714,0.000030333287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016005113,0.00008606098,0.00012985573,0.00023012797,0.000085777574,0.000021357955,0.00038183233,0.000094545445,0.0000046560763],"category_scores_gemma":[0.00078999775,0.000057416135,0.000037654398,0.00080723426,0.00008968559,0.00003202705,0.00015526138,0.00010552565,0.0000010609261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034627767,0.000020309548,0.0009401977,0.000046777666,0.000002918468,1.420829e-8,0.00040240536,0.0038515646,0.9926537,0.001769806,0.00010880335,0.00016883097],"study_design_scores_gemma":[0.0001537745,0.00005890706,0.006332021,0.00022820044,0.0000021314647,7.086513e-7,0.0005701254,0.0020323968,0.9880643,0.0024438878,0.00003380343,0.00007972595],"about_ca_topic_score_codex":0.000013364061,"about_ca_topic_score_gemma":0.0000012587175,"teacher_disagreement_score":0.0053918236,"about_ca_system_score_codex":0.0000306415,"about_ca_system_score_gemma":0.000029829549,"threshold_uncertainty_score":0.2341362},"labels":[],"label_agreement":null},{"id":"W4376954750","doi":"10.1016/j.acthis.2023.152045","title":"KCCs, NKCCs, and NCC: Potential targets for cardiovascular therapeutics? A comprehensive review of cell and region specific expression and function","year":2023,"lang":"en","type":"review","venue":"Acta Histochemica","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Scarborough Hospital; Krembil Foundation; University of Toronto","funders":"","keywords":"Internal medicine; Homeostasis; Endocrinology; Depolarization; Cardiomyopathy; Biology; Heart failure; Cell biology; Medicine","score_opus":0.04124284094410354,"score_gpt":0.27102880529774775,"score_spread":0.2297859643536442,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4376954750","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015980899,0.9966288,0.0018698644,0.000010161768,0.00018816796,0.0010678762,0.000043818116,0.000011555635,0.000019932886],"genre_scores_gemma":[0.00018574597,0.9977343,0.0009781851,0.00004658203,0.00021972973,0.000112392125,0.00054180616,0.00007040143,0.00011084449],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985175,0.000084384556,0.00042502303,0.00064069004,0.0001419228,0.00019046986],"domain_scores_gemma":[0.99903196,0.000035007102,0.00032735185,0.0004060534,0.0001235107,0.00007612008],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017132421,0.00034501194,0.001070898,0.00005718969,0.00008462641,0.000015965006,0.00011200828,0.00037943936,0.0000049712435],"category_scores_gemma":[0.000017684026,0.00029852023,0.00051981775,0.000059832622,0.00008967453,0.0000049983755,0.0001518031,0.00013661486,5.5347306e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006214422,0.000024333274,1.5861109e-7,0.102670185,0.000590602,0.0000032425103,0.000018179238,1.0719847e-7,0.6875063,0.000007540329,0.0067086653,0.20240852],"study_design_scores_gemma":[0.0003116743,0.00017266165,1.1650141e-7,0.011401283,0.0011537013,0.00003597329,0.000016670432,0.0000020380496,0.018176192,0.00003440536,0.9683996,0.00029571445],"about_ca_topic_score_codex":0.0000022332822,"about_ca_topic_score_gemma":6.594189e-8,"teacher_disagreement_score":0.9616909,"about_ca_system_score_codex":0.000018865245,"about_ca_system_score_gemma":0.000042877975,"threshold_uncertainty_score":0.9999467},"labels":[],"label_agreement":null},{"id":"W4377010573","doi":"10.1021/acs.jafc.3c01544","title":"ACE2 Activation by Tripeptide IRW (Ile-Arg-Trp) Depends on the G Protein-Coupled Receptor 30 Signaling Cascade","year":2023,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"GPER; Receptor; Chemistry; Molecular biology; Cell biology; Biochemistry; Pharmacology; Biology; Estrogen receptor","score_opus":0.009958830455594437,"score_gpt":0.2044159755584669,"score_spread":0.1944571451028725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377010573","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99830794,0.00036199292,0.00005446409,0.00090873276,0.00007886376,0.00012804015,0.000015353893,0.000012011853,0.00013259414],"genre_scores_gemma":[0.9976225,0.00021055821,0.00008597157,0.00009176958,0.0007404394,0.000013947435,0.00007570003,0.000014326833,0.0011448015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988909,0.00003542926,0.00034402678,0.00021160937,0.0002802245,0.00023783903],"domain_scores_gemma":[0.9992472,0.00003620738,0.0003421701,0.0001070315,0.00015049861,0.0001169276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002937013,0.00020409944,0.00019707262,0.000017047645,0.00018490382,0.00007156565,0.00020347351,0.0002033628,0.00014742707],"category_scores_gemma":[0.000113382186,0.00010872361,0.00016183057,0.00014349885,0.00003067508,0.000014346211,0.00005491086,0.00029924445,0.0000054184907],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006506113,0.000029071049,0.000010118526,0.0000266489,0.00010125892,9.811682e-7,0.000057932233,0.00006552474,0.992011,0.0000069685802,0.0071472763,0.00047815492],"study_design_scores_gemma":[0.0004842169,0.00040911985,0.00013596601,0.00010421466,0.000020390722,0.0000395652,0.0009458098,0.000011057759,0.99446756,0.000035609595,0.0031657668,0.0001807554],"about_ca_topic_score_codex":0.000002140301,"about_ca_topic_score_gemma":2.9968444e-7,"teacher_disagreement_score":0.0039815092,"about_ca_system_score_codex":0.000025615185,"about_ca_system_score_gemma":0.000029531739,"threshold_uncertainty_score":0.443362},"labels":[],"label_agreement":null},{"id":"W4378084179","doi":"10.3389/fpsyt.2023.1186397","title":"Chronic tianeptine induces tolerance in analgesia and hyperlocomotion via mu-opioid receptor activation in mice","year":2023,"lang":"en","type":"article","venue":"Frontiers in Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"National Institutes of Health; National Institute of Mental Health; Université de Strasbourg; National Institute on Drug Abuse; Canada Research Chairs","keywords":"Tianeptine; Pharmacology; Analgesic; Agonist; Opioid; μ-opioid receptor; Psychology; Chemistry; Medicine; Neuroscience; Receptor; Internal medicine; Antidepressant; Hippocampus","score_opus":0.0054949371435596295,"score_gpt":0.22364279022561198,"score_spread":0.21814785308205234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378084179","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925649,0.001519392,0.0032162464,0.0003800891,0.002036862,0.00020676572,0.0000027793449,0.000013123352,0.00005982066],"genre_scores_gemma":[0.9933335,0.0006124963,0.005333025,0.00009052278,0.000364181,0.000035932295,0.000115879084,0.000020497891,0.000093952774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899906,0.00006545306,0.00024968197,0.0003545918,0.00008780673,0.00024339955],"domain_scores_gemma":[0.99974954,0.000004228918,0.00006918671,0.00012779016,0.000013257682,0.000035988076],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025589782,0.00013377887,0.00016246072,0.00024646474,0.00003225514,0.0000148826975,0.000106958796,0.00019952547,0.000017911032],"category_scores_gemma":[0.000014778643,0.0001467924,0.000030052302,0.00043876804,0.00002458975,0.000013665705,0.000033299504,0.00016473189,0.0000040232007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009039526,0.000053136882,0.08366371,0.00007142549,0.000011866541,8.824964e-7,0.00017951145,0.00067159353,0.88919795,0.000029230094,0.004850244,0.021180056],"study_design_scores_gemma":[0.0072553568,0.0009988007,0.36071962,0.0009771422,0.000019317022,0.000007665286,0.002805312,0.013250288,0.59637064,0.005066165,0.011041315,0.0014883835],"about_ca_topic_score_codex":0.00006377246,"about_ca_topic_score_gemma":0.00021047471,"teacher_disagreement_score":0.2928273,"about_ca_system_score_codex":0.00005459765,"about_ca_system_score_gemma":0.000062498446,"threshold_uncertainty_score":0.598602},"labels":[],"label_agreement":null},{"id":"W4378348677","doi":"10.1111/dom.15099","title":"Safety, tolerability, pharmacodynamics and pharmacokinetics of the soluble guanylyl cyclase activator <scp>BI</scp> 685509 in patients with diabetic kidney disease: A randomized trial","year":2023,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Department of Medicine, University of Toronto; Canadian Institutes of Health Research; Kidney Foundation of Canada; University of Toronto; Diabetes Canada; Boehringer Ingelheim","keywords":"Placebo; Medicine; Renal function; Albuminuria; Internal medicine; Kidney disease; Tolerability; Creatinine; Pharmacodynamics; Urology; Endocrinology; Gastroenterology; Adverse effect; Pharmacokinetics; Pharmacology; Pathology","score_opus":0.004590596198653822,"score_gpt":0.21367781500390212,"score_spread":0.2090872188052483,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378348677","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997127,0.00081640197,0.00004687709,0.00008578756,0.00046907985,0.0012380395,0.00017305916,0.00001629891,0.000027454838],"genre_scores_gemma":[0.9983284,0.00083235244,0.00008577295,0.00024979824,0.00011830305,0.00007485921,0.00015530628,0.000028435185,0.00012677345],"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","domain_scores_codex":[0.9982226,0.00033246857,0.0003791461,0.00041660687,0.00026604833,0.00038312742],"domain_scores_gemma":[0.9990514,0.00014644225,0.00017973971,0.00027586814,0.00009153762,0.00025499272],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007238727,0.0002560195,0.0005889083,0.0000827141,0.00013184908,0.000038579165,0.00019549314,0.00011400487,0.000011225324],"category_scores_gemma":[0.0005435809,0.00018015063,0.00014408251,0.00025808424,0.00024341737,0.000017662192,0.00029344435,0.00016221235,7.6126105e-7],"study_design_candidate":"randomized_trial","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.10808254,0.0028338074,0.40086967,0.0010078346,0.0012547928,0.000004698085,0.0010000772,0.00072389754,0.47655478,0.00081797445,0.0013283379,0.0055216076],"study_design_scores_gemma":[0.66987735,0.000217758,0.12858899,0.00013948855,0.0007101868,2.231684e-7,0.000047523485,0.0035013163,0.18986575,0.0011053976,0.00557788,0.00036810228],"about_ca_topic_score_codex":0.000010623365,"about_ca_topic_score_gemma":0.000002356636,"teacher_disagreement_score":0.5617948,"about_ca_system_score_codex":0.000008433754,"about_ca_system_score_gemma":0.000089996975,"threshold_uncertainty_score":0.73463297},"labels":[],"label_agreement":null},{"id":"W4378718044","doi":"10.7554/elife.83477","title":"Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics","year":2023,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Office of Advanced Cyberinfrastructure; National Institutes of Health; Japan Science and Technology Agency; National Health and Medical Research Council; Monash University; Precursory Research for Embryonic Science and Technology; National Energy Research Scientific Computing Center; Takeda Science Foundation; Australian Research Council; Wellcome Trust; National Institute of General Medical Sciences; Medical Research Council; Wellcome","keywords":"Allosteric regulation; Drug discovery; Allosteric modulator; G protein-coupled receptor; Cooperativity; Agonist; Biophysics; Muscarinic acetylcholine receptor; Chemistry; Allosteric enzyme; Receptor; Neuroscience; Computational biology; Pharmacology; Biology; Biochemistry","score_opus":0.013197843674789893,"score_gpt":0.2657993716343126,"score_spread":0.25260152795952273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378718044","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9981717,0.00055714196,0.00013413823,0.00035852595,0.00029621992,0.0001406365,0.000088641216,0.000018175513,0.00023482545],"genre_scores_gemma":[0.99670064,0.0011080176,0.00026255692,0.00042619056,0.00016187866,0.000007788567,0.0004394172,0.00001683009,0.0008766592],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99917454,0.000068994086,0.00018208702,0.00025173437,0.00013836216,0.0001842818],"domain_scores_gemma":[0.9996268,0.00002597899,0.000078528734,0.00017666508,0.000049293507,0.000042732205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001668333,0.00011983798,0.00013787826,0.000014902134,0.00009372519,0.000012596968,0.0001539255,0.00016425808,0.00042929768],"category_scores_gemma":[0.000042626845,0.00008046595,0.000065244196,0.00009762229,0.000085030144,0.000003029694,0.00028062164,0.000099802106,0.00001080725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006613509,0.000009085981,0.00054785976,0.000011479411,0.00007339217,0.0000016030518,0.00007787199,0.00006460853,0.9917461,0.00010064371,0.006084119,0.001217053],"study_design_scores_gemma":[0.00041018688,0.00016598593,0.0010202074,0.000009525981,0.000030083009,0.000008303184,0.00017071315,0.0006464851,0.975768,0.00008066884,0.02154771,0.00014208988],"about_ca_topic_score_codex":0.000010550634,"about_ca_topic_score_gemma":0.00002976745,"teacher_disagreement_score":0.01597811,"about_ca_system_score_codex":0.000011923723,"about_ca_system_score_gemma":0.000021836726,"threshold_uncertainty_score":0.47005087},"labels":[],"label_agreement":null},{"id":"W4378800761","doi":"10.7554/elife.86628.3","title":"Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution","year":2023,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Genève; University of Toronto; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Receptor; Liraglutide; Glucagon-like peptide 1 receptor; G protein-coupled receptor; Glucose homeostasis; Glucagon receptor; Peptide; HEK 293 cells; Förster resonance energy transfer; Glucagon; Chemistry; Fluorescence; Cell biology; Biophysics; Biology; Biochemistry; Hormone; Endocrinology; Insulin; Physics; Insulin resistance; Type 2 diabetes; Agonist","score_opus":0.027636492301425074,"score_gpt":0.28783644087333204,"score_spread":0.260199948571907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378800761","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9541985,0.000036222365,0.045135487,0.00019955567,0.000077469624,0.00026231766,0.000010268101,0.00003289438,0.00004732187],"genre_scores_gemma":[0.99272996,0.000032149448,0.005947057,0.00010769722,0.00044758676,0.00005263693,0.0005131268,0.000022420058,0.00014734424],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99930024,0.000023636047,0.00014329309,0.00023782892,0.000118648786,0.00017634901],"domain_scores_gemma":[0.9996771,0.00003172254,0.00006222028,0.00009597422,0.000080640144,0.000052307816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027189264,0.00009519601,0.00011265725,0.000035521287,0.00017007647,0.00006344998,0.000044278906,0.00010396575,0.000011844189],"category_scores_gemma":[0.00011544611,0.00008421002,0.000031045543,0.00006232903,0.000024126366,0.000011640621,0.000027157697,0.000045147946,0.0000030380347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001543172,0.000009534795,0.00010449617,0.000013549321,0.000023533912,2.1234005e-7,0.000030684692,0.00017338934,0.99477994,0.0025006824,0.00058904785,0.0016206021],"study_design_scores_gemma":[0.0010010902,0.00051684096,0.0005262828,0.000034634966,0.0000109772445,7.0510555e-7,0.00012809958,0.00096978707,0.98731375,0.00008265703,0.009268101,0.00014709194],"about_ca_topic_score_codex":0.000015206855,"about_ca_topic_score_gemma":0.000006178712,"teacher_disagreement_score":0.03918843,"about_ca_system_score_codex":0.000011259046,"about_ca_system_score_gemma":0.00002305005,"threshold_uncertainty_score":0.34339848},"labels":[],"label_agreement":null},{"id":"W4380355313","doi":"10.1073/pnas.2300008120","title":"The mRNA translation initiation factor eIF4G1 controls mitochondrial oxidative phosphorylation, axonal morphogenesis, and memory","year":2023,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University; National Research Foundation of Korea; Ministry of Education, Culture, Sports, Science and Technology; National Research Foundation; Government of Canada","keywords":"EIF4G; EIF4E; Cell biology; Biology; Translation (biology); Initiation factor; Eukaryotic initiation factor; Eukaryotic translation; Messenger RNA; Genetics; Gene","score_opus":0.03598894252753066,"score_gpt":0.286285128776206,"score_spread":0.25029618624867533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380355313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976523,0.00042753815,0.000036717105,0.0011559055,0.000055308392,0.00022893728,0.000040232193,0.0000061965807,0.0003968585],"genre_scores_gemma":[0.9988956,0.00020994291,0.00056367187,0.00007764362,0.00015408538,0.000016252921,0.0000027677324,0.000003929262,0.00007610036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989373,0.000012106493,0.00022833805,0.00018236774,0.00053318834,0.00010670761],"domain_scores_gemma":[0.9993952,0.000091747075,0.00025951018,0.0000074052555,0.00022443695,0.000021713828],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006467283,0.000073447736,0.00008117835,0.00005216435,0.00031841404,0.00003145276,0.00024981386,0.00008337426,0.000010264339],"category_scores_gemma":[0.0002953559,0.00004566355,0.000050058843,0.0002577712,0.0002925866,0.000030911287,0.0000462646,0.00005847013,8.30617e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003831438,0.000005390488,0.00047413737,0.000007140744,0.000015959646,1.1109058e-9,0.00008842487,0.000108686596,0.99578947,0.0020649666,0.00027794007,0.0011295949],"study_design_scores_gemma":[0.00026770504,0.0000506559,0.013080634,0.000013505256,0.0000069025505,0.0000013479149,0.00021350337,0.0009929565,0.97896755,0.005548254,0.0007970181,0.00005998866],"about_ca_topic_score_codex":0.000002346292,"about_ca_topic_score_gemma":1.826662e-7,"teacher_disagreement_score":0.016821915,"about_ca_system_score_codex":0.000007390659,"about_ca_system_score_gemma":0.000036370442,"threshold_uncertainty_score":0.24490155},"labels":[],"label_agreement":null},{"id":"W4380364386","doi":"10.7554/elife.88058.2.sa4","title":"Author response: Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biological and Environmental Research; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Office of Science; Oregon Health and Science University; U.S. Department of Energy; National Science Foundation; National Institutes of Health; Michael Smith Health Research BC","keywords":"Allosteric regulation; Protein subunit; Phosphorylation; Chemistry; Protein kinase domain; Protein kinase C; Cell biology; Biophysics; Conformational change; Protein kinase A; Biochemistry; Receptor; Biology; Mutant","score_opus":0.06168687779236064,"score_gpt":0.34280974474697873,"score_spread":0.2811228669546181,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380364386","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.28585836,0.010364962,0.025223713,0.65452415,0.004819765,0.009371951,0.0043799607,0.00021351034,0.0052436525],"genre_scores_gemma":[0.14114778,0.035542283,0.011441349,0.092245385,0.0057944357,0.004118953,0.16935956,0.00061647303,0.53973377],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980839,0.00041430973,0.0005144842,0.00029725366,0.00047612897,0.00021391983],"domain_scores_gemma":[0.9989761,0.0002038955,0.00031708847,0.00028604057,0.0001865822,0.000030303892],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015719604,0.00023797044,0.00035302504,0.000094659656,0.000052466752,0.000022493685,0.00021969364,0.00045125996,0.00078044995],"category_scores_gemma":[0.0006300369,0.00015025317,0.00011469731,0.00032112465,0.00004892418,0.00000752068,0.00010099961,0.00021631498,0.00002410433],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00061492895,0.00005202072,7.106158e-7,0.00078038336,0.000052054504,0.0000041088333,0.00028674316,0.000004788302,0.43678436,0.00020446438,0.56058,0.000635453],"study_design_scores_gemma":[0.00046122377,0.00048461038,0.00003933726,0.0012029505,0.000026486896,0.000013460232,0.00039843624,0.000020350933,0.13388523,0.00021477627,0.8629996,0.0002535179],"about_ca_topic_score_codex":0.00004782337,"about_ca_topic_score_gemma":0.00019579066,"teacher_disagreement_score":0.56227875,"about_ca_system_score_codex":0.00002904234,"about_ca_system_score_gemma":0.00022009008,"threshold_uncertainty_score":0.85453796},"labels":[],"label_agreement":null},{"id":"W4380483235","doi":"10.7554/elife.87754.1","title":"β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Queen's University Belfast; Biotechnology and Biological Sciences Research Council; LEO Fondet; Department for the Economy; Queen's University; Wellcome Trust","keywords":"Endosome; Arrestin; Receptor; Cell biology; Vasopressin; Chemistry; Vasopressin receptor; Endocrinology; G protein-coupled receptor; Internal medicine; Biology; Biochemistry; Antagonist; Medicine","score_opus":0.022736510589650046,"score_gpt":0.25480019768616274,"score_spread":0.2320636870965127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380483235","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98537546,0.00090275833,0.009521282,0.00086989853,0.0010840482,0.0012830789,0.00006585855,0.00008923409,0.00080836547],"genre_scores_gemma":[0.9785476,0.00032426667,0.0012834538,0.00015331266,0.0006183055,0.000241652,0.0006958483,0.00008319386,0.018052423],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99825156,0.00013537837,0.00028388627,0.0007211642,0.00032632262,0.0002816935],"domain_scores_gemma":[0.99906254,0.000023833947,0.0001930605,0.0005185551,0.00011133266,0.00009066088],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039222915,0.00031021435,0.00020610965,0.00003793779,0.00015792075,0.00016067806,0.00035779053,0.000489027,0.00024138937],"category_scores_gemma":[0.00013994353,0.00022328836,0.00008498839,0.00005797745,0.000047855974,0.0000037461284,0.00093089347,0.00042681766,0.0000331884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064697604,0.000028649989,0.00008024421,0.00004122796,0.000088477434,0.0000010161465,0.000035198507,0.000100556616,0.988326,0.0001226026,0.008824901,0.0022864349],"study_design_scores_gemma":[0.00027701625,0.00013417962,0.000081659055,0.00007891651,0.000022228443,0.0000039801093,0.00011787089,0.00015195011,0.98695487,0.0006771965,0.011181175,0.00031895115],"about_ca_topic_score_codex":0.00023016868,"about_ca_topic_score_gemma":0.000024880075,"teacher_disagreement_score":0.017244058,"about_ca_system_score_codex":0.000027067073,"about_ca_system_score_gemma":0.00012133978,"threshold_uncertainty_score":0.91054344},"labels":[],"label_agreement":null},{"id":"W4380488627","doi":"10.7554/elife.87754","title":"β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor","year":2023,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Directorate for Biological Sciences; National Cancer Institute; National Institutes of Health; Biotechnology and Biological Sciences Research Council; LEO Fondet; Queen's University Belfast; Department for the Economy; UK Research and Innovation; Queen's University; Wellcome Trust","keywords":"Arrestin; Endosome; Cell biology; Vasopressin receptor; Receptor; Chemistry; Biology; G protein-coupled receptor; Signal transduction; Antagonist; Biochemistry","score_opus":0.01216974144884417,"score_gpt":0.23875735916240243,"score_spread":0.22658761771355826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380488627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99785084,0.00034213965,0.00055376254,0.0004507066,0.0002183869,0.00026625596,0.000010272169,0.000033764092,0.00027385115],"genre_scores_gemma":[0.99556804,0.00012188758,0.00019155159,0.00016969514,0.00029594245,0.000048750262,0.0001186523,0.000021552121,0.0034639153],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991358,0.00006409694,0.00012609793,0.00025809425,0.00022692328,0.00018900921],"domain_scores_gemma":[0.99962395,0.000014173961,0.000059942933,0.00019052949,0.000052643052,0.000058777376],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002641616,0.000110205714,0.00007674112,0.000021088163,0.0001438417,0.00004895432,0.00012969207,0.00010223365,0.00010004399],"category_scores_gemma":[0.00011687474,0.000080841295,0.00002890204,0.00009579845,0.000025709052,0.0000047412755,0.00011348904,0.000096924414,0.0000540715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036602196,0.000012325565,0.00017617714,0.000005284192,0.000018820303,7.094916e-7,0.000039359806,0.00001959961,0.98606473,0.00008200806,0.010742901,0.00280147],"study_design_scores_gemma":[0.0002444098,0.00010619892,0.00029252865,0.000012894502,0.0000045655847,0.000002850213,0.00010363138,0.00008513403,0.950334,0.00003705446,0.048669543,0.000107149775],"about_ca_topic_score_codex":0.00002547446,"about_ca_topic_score_gemma":0.000003493633,"teacher_disagreement_score":0.03792664,"about_ca_system_score_codex":0.000008788858,"about_ca_system_score_gemma":0.000035325364,"threshold_uncertainty_score":0.32966122},"labels":[],"label_agreement":null},{"id":"W4380628808","doi":"10.7554/elife.87754.1.sa2","title":"Reviewer #1 (Public Review): β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Queen's University Belfast; LEO Fondet; Department for the Economy; Queen's University; Wellcome Trust","keywords":"Endosome; G protein-coupled receptor; Arrestin; Internalization; Cell biology; G protein; Receptor; Signal transduction; Chemistry; Biology; Biochemistry","score_opus":0.030504910834287535,"score_gpt":0.28692114234766664,"score_spread":0.2564162315133791,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380628808","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005868806,0.9452486,0.0009978036,0.03991576,0.004646514,0.0057119485,0.00030120582,0.00011250197,0.0024788056],"genre_scores_gemma":[0.00019342624,0.54964936,0.00031175974,0.007012872,0.0014309026,0.00078341167,0.0049757804,0.0001484861,0.43549404],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9964409,0.00046024818,0.0007848305,0.0010280131,0.0007952522,0.0004907561],"domain_scores_gemma":[0.9971876,0.00004992926,0.00057755306,0.0009818238,0.0010225653,0.00018051932],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016909663,0.00059778546,0.00076966995,0.000052415806,0.00021198248,0.00011305952,0.0006653665,0.0004938109,0.002085951],"category_scores_gemma":[0.002765068,0.00039326109,0.00025681194,0.0002777825,0.00006678225,0.000011171801,0.0004945751,0.0006059934,0.00013764262],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009436578,0.00003054356,0.0000022551385,0.0042587197,0.00010916772,0.0000010456869,0.0000027159163,1.7568537e-7,0.0895804,0.000022168178,0.88873327,0.017250119],"study_design_scores_gemma":[0.00018891082,0.00016747175,0.0000024121002,0.011000018,0.00013161791,0.00000851145,0.00000806921,0.0000026174637,0.03598064,0.000018088585,0.95202965,0.00046198],"about_ca_topic_score_codex":0.00009623387,"about_ca_topic_score_gemma":0.000033843946,"teacher_disagreement_score":0.43301523,"about_ca_system_score_codex":0.00004881234,"about_ca_system_score_gemma":0.00026811438,"threshold_uncertainty_score":0.99985194},"labels":[],"label_agreement":null},{"id":"W43810226","doi":"10.1007/978-0-387-26575-9_144","title":"Agonist Activation of the Angiotensin II Type 1 Receptor Alters the Spatial Proximity of Transmembrane Domain 7 to the Ligand Binding Pocket","year":2010,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Agonist; Chemistry; Transmembrane domain; Ligand (biochemistry); Transmembrane protein; Angiotensin II; Biophysics; Cell biology; Domain (mathematical analysis); Receptor; Biochemistry; Biology; Mathematics","score_opus":0.011147641877812205,"score_gpt":0.21599745458627634,"score_spread":0.20484981270846414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W43810226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95884174,0.00027272504,0.007056255,0.006706796,0.002121555,0.0026141845,0.00022779217,0.000018434996,0.022140516],"genre_scores_gemma":[0.9511435,0.00011598978,0.0014918405,0.0006794682,0.00073000224,0.000012394292,0.00015826694,0.000075714335,0.04559284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989117,0.000045381326,0.0003278262,0.00029315904,0.00025875418,0.00016320293],"domain_scores_gemma":[0.99889994,0.000026350832,0.00028470915,0.0005775958,0.0001708245,0.000040557654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039321734,0.00023777646,0.00024721844,0.000033649565,0.00026345483,0.000018671692,0.00043594945,0.00039229685,0.0002771547],"category_scores_gemma":[0.000035484918,0.00011621143,0.0002478734,0.000048908965,0.0001506519,0.0000030032863,0.00014058001,0.00029019782,0.0000032834773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013978768,0.000013045421,0.0000020303662,0.000016863534,0.00009194098,8.009746e-8,0.00023104578,0.000014115995,0.9952892,0.0016359915,0.0008587117,0.0017071851],"study_design_scores_gemma":[0.00015185642,0.00023077916,0.000008210185,0.00006977826,0.000040801126,0.0000023152784,0.000046269368,0.000004690791,0.8874739,0.00035976345,0.11147024,0.00014139153],"about_ca_topic_score_codex":0.000093920906,"about_ca_topic_score_gemma":0.00016694675,"teacher_disagreement_score":0.11061153,"about_ca_system_score_codex":0.000011800717,"about_ca_system_score_gemma":0.000115914976,"threshold_uncertainty_score":0.47389644},"labels":[],"label_agreement":null},{"id":"W4381154306","doi":"10.5281/zenodo.8055068","title":"Investigating the Aryl Hydrocarbon Receptor Agonist/Antagonist Conformational Switch using Well-Tempered Metadynamics Simulations input and output files","year":2023,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Metadynamics; Agonist; Aryl; Aryl hydrocarbon receptor; Chemistry; Antagonist; Hydrocarbon; Computer science; Stereochemistry; Receptor; Computational chemistry; Molecular dynamics; Organic chemistry; Biochemistry","score_opus":0.035374124844672304,"score_gpt":0.2538952234895455,"score_spread":0.2185210986448732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381154306","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99067163,0.000085645486,0.004698876,0.00047698483,0.00012474204,0.00034487678,0.0002736144,0.00018512321,0.0031385287],"genre_scores_gemma":[0.99346775,0.00008471768,0.0006013852,0.00014686886,0.00017592397,9.269446e-8,0.0048122816,0.00035944025,0.00035156243],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99883956,0.00012144677,0.00025422667,0.00028994598,0.00023729783,0.00025752163],"domain_scores_gemma":[0.9992706,0.000024854595,0.00011999795,0.00025627378,0.0002233907,0.0001048513],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00052230275,0.00013680555,0.00010935233,0.0000983702,0.0024026604,0.0005255521,0.00036206678,0.00008515953,0.00063433487],"category_scores_gemma":[0.0003506609,0.00012153943,0.00004608276,0.0003180017,0.00016185382,0.000026305075,0.0005050406,0.00015541897,0.00025973006],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022796337,0.00002387206,0.00002530168,0.00004331207,0.000083099214,0.0000011535903,0.00079602294,0.006604611,0.97468764,0.0020041438,0.009568528,0.0061395047],"study_design_scores_gemma":[0.0008074948,0.00024104645,0.00035042994,0.00006399984,0.000048999816,0.00008894616,0.0019772532,0.2105201,0.069770545,0.00053718727,0.71511286,0.00048113393],"about_ca_topic_score_codex":0.0000166523,"about_ca_topic_score_gemma":7.465009e-7,"teacher_disagreement_score":0.9049171,"about_ca_system_score_codex":0.00003335044,"about_ca_system_score_gemma":0.000011648088,"threshold_uncertainty_score":0.99889606},"labels":[],"label_agreement":null},{"id":"W4381436960","doi":"10.7554/elife.86628.2.sa0","title":"Author Response: Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Genève; University of Toronto; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Liraglutide; Receptor; Glucagon-like peptide 1 receptor; G protein-coupled receptor; Fluorescence; Chemistry; HEK 293 cells; Derivative (finance); Förster resonance energy transfer; Biophysics; Cell biology; Biology; Biochemistry; Endocrinology; Physics; Agonist; Type 2 diabetes; Diabetes mellitus","score_opus":0.059859442593208134,"score_gpt":0.3525668204452048,"score_spread":0.2927073778519967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381436960","genre_codex":"methods","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.298646,0.013362032,0.5724117,0.09483993,0.0048735896,0.012747045,0.0018030636,0.0005692062,0.00074745296],"genre_scores_gemma":[0.16868784,0.0039009773,0.10636178,0.0048059863,0.00862315,0.0028263784,0.05902955,0.0010168459,0.6447475],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978588,0.00018149293,0.00051025127,0.00075833336,0.00032051018,0.00037061347],"domain_scores_gemma":[0.9986756,0.00019849646,0.00031836866,0.00032139107,0.00036480327,0.00012138236],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0015371764,0.00037972542,0.0005718239,0.00010124056,0.00027310834,0.00015570506,0.00015319884,0.0005966043,0.00010889138],"category_scores_gemma":[0.0009039776,0.0003178563,0.00014555361,0.0001127435,0.000058091868,0.00001452096,0.000089551184,0.00022274477,0.0000049733285],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015034468,0.000028794868,0.000002038253,0.0008535414,0.00016837394,9.704278e-7,0.000015041364,0.000028072996,0.70713454,0.0010904997,0.2855886,0.0035860625],"study_design_scores_gemma":[0.0012939804,0.0016538571,0.000023911489,0.0020883314,0.00015972296,0.0000034882596,0.000060940925,0.00016067659,0.26071402,0.00010491477,0.73312443,0.00061170873],"about_ca_topic_score_codex":0.00007494632,"about_ca_topic_score_gemma":0.000046130557,"teacher_disagreement_score":0.64400005,"about_ca_system_score_codex":0.0000569386,"about_ca_system_score_gemma":0.00017792563,"threshold_uncertainty_score":0.99992734},"labels":[],"label_agreement":null},{"id":"W4381682806","doi":"10.1172/jci166248","title":"Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; BC Cancer Agency","funders":"National Institutes of Health; National Institute of General Medical Sciences; Northwestern University; National Cancer Institute; Prostate Cancer Foundation","keywords":"Cell biology; Mitosis; Aurora A kinase; Aurora kinase; Biology; Cancer research; Microtubule; Mitotic catastrophe; Kinase; Aurora inhibitor; Signal transduction; Cell cycle; Cell; Genetics","score_opus":0.042031984336666356,"score_gpt":0.3437467991179001,"score_spread":0.30171481478123374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381682806","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952031,0.00024357408,0.00008167427,0.0038541227,0.00046384044,0.00012166568,0.0000075965672,0.000011601316,0.000012842955],"genre_scores_gemma":[0.99422026,0.0023261358,0.00159101,0.0005070664,0.00094532856,0.000008440953,0.000031141015,0.000023562345,0.00034705317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986424,0.00013042144,0.00068345823,0.00020345006,0.00017798512,0.00016232135],"domain_scores_gemma":[0.99885863,0.00007667422,0.00052007893,0.000092967806,0.00025422007,0.00019740808],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071976543,0.00011887651,0.00025126387,0.00006338338,0.000054933324,0.000037476828,0.00010171551,0.00007407236,0.00004342503],"category_scores_gemma":[0.0015060889,0.00009400624,0.00010824648,0.000168814,0.00010103255,0.000019873829,0.00006196242,0.00021843782,0.0000041534736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001710449,0.00003245198,0.017380344,0.000039413168,0.0000534936,0.000012630629,0.00004357489,0.000030774154,0.9704703,0.000079184014,0.003221552,0.008465217],"study_design_scores_gemma":[0.0009537999,0.0008863056,0.007874401,0.000099880104,0.000033274795,0.00002397847,0.000041141495,0.00038667556,0.981221,0.0027980627,0.005549867,0.000131568],"about_ca_topic_score_codex":0.000009215706,"about_ca_topic_score_gemma":0.000001963216,"teacher_disagreement_score":0.010750725,"about_ca_system_score_codex":0.0000065263785,"about_ca_system_score_gemma":0.00012402062,"threshold_uncertainty_score":0.38334632},"labels":[],"label_agreement":null},{"id":"W4381826758","doi":"10.7554/elife.86628.2.sa2","title":"eLife Assessment: Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Genève; University of Toronto; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Liraglutide; Receptor; Glucagon-like peptide 1 receptor; Fluorescence; Chemistry; G protein-coupled receptor; Derivative (finance); Biophysics; Cell biology; Biochemistry; Biology; Endocrinology; Physics; Agonist","score_opus":0.045965670768864916,"score_gpt":0.35083762600391927,"score_spread":0.30487195523505434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4381826758","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.072834216,0.008600293,0.8823703,0.01907226,0.003394946,0.009268455,0.0011703209,0.00037189035,0.0029173414],"genre_scores_gemma":[0.28826973,0.034567494,0.26931673,0.009659216,0.016493298,0.0043034847,0.1945013,0.0013885496,0.18150021],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99800575,0.00008428826,0.0004956172,0.000713168,0.000354356,0.00034682773],"domain_scores_gemma":[0.99880797,0.00009319286,0.00033488352,0.00027944858,0.00037495297,0.000109535016],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00079743157,0.0003675415,0.000573789,0.00007650601,0.0002514827,0.00017061796,0.00014245324,0.00048743078,0.00010277953],"category_scores_gemma":[0.0002374266,0.00030747746,0.00013900036,0.000091025955,0.000046046363,0.000016639196,0.00008865744,0.0002260793,0.0000030061917],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002343059,0.00007032652,0.000013207247,0.001998005,0.00041166437,0.0000011238532,0.0000122674355,0.000081935505,0.74738145,0.005306134,0.23528142,0.009208141],"study_design_scores_gemma":[0.0023537914,0.0019113193,0.000041428742,0.0033508209,0.00031427352,0.0000035334992,0.00008460846,0.00063474313,0.2387406,0.000178668,0.75136995,0.0010162604],"about_ca_topic_score_codex":0.00010285427,"about_ca_topic_score_gemma":0.000058146074,"teacher_disagreement_score":0.61305356,"about_ca_system_score_codex":0.000057323832,"about_ca_system_score_gemma":0.00017017446,"threshold_uncertainty_score":0.9999377},"labels":[],"label_agreement":null},{"id":"W4382318688","doi":"10.1609/aaai.v37i12.26650","title":"On the Challenges of Using Reinforcement Learning in Precision Drug Dosing: Delay and Prolongedness of Action Effects","year":2023,"lang":"en","type":"article","venue":"Proceedings of the AAAI Conference on Artificial Intelligence","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Institut de Valorisation des Données","keywords":"Partially observable Markov decision process; Reinforcement learning; Markov decision process; Computer science; Dosing; Action (physics); Markov chain; Task (project management); Markov process; Artificial intelligence; Baseline (sea); Machine learning; Markov model; Medicine; Pharmacology; Mathematics; Biology","score_opus":0.07934898163826612,"score_gpt":0.31132576034773424,"score_spread":0.23197677870946812,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382318688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986849,0.00006271508,0.00041962307,0.00018072869,0.0000970517,0.0002963488,4.1161e-7,0.000005203265,0.0002530266],"genre_scores_gemma":[0.9995694,0.00029474738,0.00005390377,0.000012153748,0.000020556065,0.00001234148,4.4528662e-7,0.000008233709,0.000028184511],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916583,0.000029956625,0.00027913268,0.0001995554,0.00019664747,0.00012889644],"domain_scores_gemma":[0.99938095,0.00007729984,0.00026882658,0.00009052775,0.00016505957,0.00001732567],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006633116,0.00010279827,0.00014642972,0.000074329226,0.0000676742,0.0000146827415,0.00020729602,0.00006924766,0.000006092146],"category_scores_gemma":[0.00042098394,0.00006704292,0.000045977293,0.00017251562,0.00009463413,0.000008492699,0.00011572898,0.00012915234,8.9356223e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019259127,0.000028153356,0.000144503,0.00010175651,0.000009821703,7.242657e-8,0.000898524,0.00201582,0.94551724,0.03777774,0.000002898769,0.013310876],"study_design_scores_gemma":[0.000029714643,0.000299474,0.00012081988,0.00046673827,0.000007382085,5.05794e-7,0.0014391,0.020265961,0.96960855,0.007693162,0.000004573476,0.00006403017],"about_ca_topic_score_codex":0.00003053201,"about_ca_topic_score_gemma":0.0000072715,"teacher_disagreement_score":0.030084576,"about_ca_system_score_codex":0.000009305406,"about_ca_system_score_gemma":0.0000270513,"threshold_uncertainty_score":0.2733931},"labels":[],"label_agreement":null},{"id":"W4382813535","doi":"10.7554/elife.86628.2.sa1","title":"Public Review: Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Genève; University of Toronto; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Liraglutide; Receptor; Glucagon-like peptide 1 receptor; Fluorescence; Derivative (finance); Chemistry; Glucagon receptor; HEK 293 cells; Green fluorescent protein; Glucagon; Biophysics; Computational biology; Hormone; Biology; Biochemistry; Endocrinology; Physics; Gene","score_opus":0.08065920883749578,"score_gpt":0.3312777414857211,"score_spread":0.2506185326482253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382813535","genre_codex":"methods","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012617281,0.34503242,0.44909292,0.1574249,0.0052489345,0.023919947,0.0016929525,0.0006878085,0.0042828447],"genre_scores_gemma":[0.025380764,0.5150776,0.06861195,0.024557043,0.01099211,0.0049874727,0.17591764,0.0011003889,0.17337503],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99774915,0.0001136238,0.0006155237,0.00077560596,0.00034693128,0.0003991532],"domain_scores_gemma":[0.9984389,0.00008805011,0.00041434288,0.00036258288,0.0005608035,0.00013535043],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011494077,0.0004015694,0.0007493985,0.00008045669,0.00023661222,0.00016219463,0.0001865907,0.00045345572,0.00018137164],"category_scores_gemma":[0.0008405091,0.00032486996,0.00018224842,0.00014256159,0.000052452982,0.000022489445,0.00010218973,0.00022648464,0.0000062390227],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010097679,0.00004633711,0.0000030748154,0.009063001,0.0002689791,7.480581e-7,0.0000047978856,0.0000051942166,0.1855498,0.0026317027,0.78763664,0.014688747],"study_design_scores_gemma":[0.00085209083,0.0007803689,0.0000036843915,0.009932223,0.00021010797,0.0000033403785,0.000014314586,0.000055479344,0.044699553,0.00008667025,0.94278765,0.0005744964],"about_ca_topic_score_codex":0.000062093924,"about_ca_topic_score_gemma":0.000059401766,"teacher_disagreement_score":0.38048097,"about_ca_system_score_codex":0.00005097796,"about_ca_system_score_gemma":0.00015995599,"threshold_uncertainty_score":0.9999203},"labels":[],"label_agreement":null},{"id":"W4383264311","doi":"10.1038/s41467-023-39132-x","title":"Profiling of basal and ligand-dependent GPCR activities by means of a polyvalent cell-based high-throughput platform","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Druggability; Computational biology; Internalization; Agonist; Receptor; Drug discovery; Biology; Functional selectivity; Bioinformatics; Biochemistry","score_opus":0.01328500598823044,"score_gpt":0.26751680431648506,"score_spread":0.2542317983282546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383264311","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99286115,0.004753601,0.0012986159,0.00025784908,0.00008385667,0.00018665014,0.00021190141,0.000016834596,0.00032956788],"genre_scores_gemma":[0.99371886,0.001317969,0.0042379834,0.000062557534,0.00002047905,0.000022035738,0.00049735315,0.000015793166,0.00010698813],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937284,0.00003968539,0.00019097439,0.00014688414,0.00013053663,0.00011906962],"domain_scores_gemma":[0.999085,0.000059095128,0.0001257961,0.0006363439,0.000060250837,0.00003350253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019291171,0.00009636424,0.00014121835,0.000053366777,0.000096955584,0.000008989804,0.0003376733,0.00022343753,0.00000675142],"category_scores_gemma":[0.000032308002,0.000091206544,0.00005135142,0.000108408574,0.0000897634,0.000005253961,0.00021790956,0.00021410543,5.592097e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023761495,0.00006793544,0.0006688959,0.00003935323,0.000028934634,1.0646028e-7,0.00007609967,0.000078440375,0.9974557,0.00081254507,0.0005468689,0.00020135341],"study_design_scores_gemma":[0.0003291106,0.000109946166,0.000114995164,0.000022648246,0.000019840863,4.6977067e-7,0.00037463606,0.0006262945,0.99693424,0.000107045875,0.0012707638,0.00008999045],"about_ca_topic_score_codex":0.000024379517,"about_ca_topic_score_gemma":0.000035834368,"teacher_disagreement_score":0.003435632,"about_ca_system_score_codex":0.000008321311,"about_ca_system_score_gemma":0.00005563511,"threshold_uncertainty_score":0.3719295},"labels":[],"label_agreement":null},{"id":"W4383888069","doi":"10.1038/s41467-023-39805-7","title":"Synaptotagmin-1-dependent phasic axonal dopamine release is dispensable for basic motor behaviors in mice","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Hôpital du Sacré-Cœur de Montréal; Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Parkinson Canada; Krembil Foundation; Michael J. Fox Foundation for Parkinson's Research","keywords":"Synaptotagmin 1; Dopamine; Neuroscience; Motor activity; Motor behavior; Chemistry; Biology; Cell biology; Endocrinology; Biochemistry; Synaptic vesicle","score_opus":0.019594047082382073,"score_gpt":0.3043876970998246,"score_spread":0.28479365001744256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383888069","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99237347,0.0034579376,0.00040089193,0.0020812366,0.0002751767,0.0006557155,0.00034387724,0.0000454641,0.00036620678],"genre_scores_gemma":[0.9925383,0.0008622283,0.002782337,0.00037455227,0.000084422456,0.0002672531,0.0013111053,0.000031428506,0.0017483783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990576,0.000059299407,0.0002276002,0.0002869356,0.00012202338,0.0002465532],"domain_scores_gemma":[0.99876153,0.000074342344,0.00007394365,0.0009089721,0.00011320041,0.00006799842],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000278703,0.00013737647,0.00013690436,0.00009710526,0.0001779864,0.000026466725,0.0006951904,0.00030339713,0.00005923793],"category_scores_gemma":[0.00012436644,0.00014032882,0.00009937946,0.00022044999,0.00004762206,0.000006653594,0.0002669686,0.00034475513,0.000028165548],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005338626,0.00015936367,0.0005987981,0.000012942884,0.00002805372,0.0000015618836,0.00006375763,0.000026763091,0.98939425,0.000982556,0.007242294,0.0014363037],"study_design_scores_gemma":[0.0021566723,0.0003791084,0.0026357276,0.000068842324,0.00009319572,0.000017924822,0.0005537682,0.0032697394,0.68004584,0.00048673808,0.3096278,0.0006646676],"about_ca_topic_score_codex":0.00003307022,"about_ca_topic_score_gemma":0.000411713,"teacher_disagreement_score":0.3093484,"about_ca_system_score_codex":0.000030075671,"about_ca_system_score_gemma":0.00006198472,"threshold_uncertainty_score":0.5722443},"labels":[],"label_agreement":null},{"id":"W4384070508","doi":"10.1093/noajnl/vdad071.044","title":"REPURPOSING OF FDA APPROVED COMPOUNDS TO INHIBIT OSM/OSMR SIGNALING IN GLIOBLASTOMA","year":2023,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Repurposing; Pharmacology; Drug repositioning; Signal transduction; Potency; Drug; Chemistry; Medicine; Biology; In vitro; Biochemistry","score_opus":0.012288482111313342,"score_gpt":0.28335554593028633,"score_spread":0.271067063818973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384070508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99675786,0.0006417263,0.0008980988,0.00020092393,0.0005245333,0.00029746784,0.000008295567,0.000041767173,0.0006293422],"genre_scores_gemma":[0.99671,0.00025337847,0.0021361043,0.0005348458,0.00018102776,0.00005583568,0.00001948556,0.0000330854,0.00007624162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983687,0.00014631414,0.00043571193,0.0005147389,0.0001524866,0.00038208664],"domain_scores_gemma":[0.9992852,0.00012982127,0.00016565458,0.00025104152,0.000077985525,0.00009026703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038834498,0.00018546528,0.0003342654,0.00020303461,0.000079285135,0.000013155012,0.00023671424,0.00018180507,0.000021499005],"category_scores_gemma":[0.0002596087,0.00019025154,0.00008935407,0.0004948705,0.00007637705,0.000012109676,0.00018240891,0.00016311368,0.000014930947],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027128274,0.00005187617,0.0008137807,0.000028538496,0.000011372834,0.000030012601,0.00017019358,0.005144588,0.98416775,0.00008327479,0.0003656947,0.008861645],"study_design_scores_gemma":[0.0005516989,0.0012901071,0.000066726076,0.0000365397,0.000007189281,0.00001726386,0.00034339583,0.0001989565,0.9192962,0.00033961041,0.07767383,0.00017849561],"about_ca_topic_score_codex":0.000009571807,"about_ca_topic_score_gemma":0.00010061746,"teacher_disagreement_score":0.07730813,"about_ca_system_score_codex":0.000026135353,"about_ca_system_score_gemma":0.00007865707,"threshold_uncertainty_score":0.77582324},"labels":[],"label_agreement":null},{"id":"W4384663251","doi":"10.1007/978-1-0716-3307-6_2","title":"Enhanced Bystander BRET (ebBRET) Biosensors as Biophysical Tools to Map the Signaling Profile of Neuropsychiatric Drugs Targeting GPCRs","year":2023,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"G protein-coupled receptor; Bioluminescence; Förster resonance energy transfer; Bystander effect; Energy transfer; Biosensor; Drug discovery; Chemistry; Computational biology; Nanotechnology; Biology; Signal transduction; Fluorescence; Biochemistry; Physics; Materials science","score_opus":0.015134696888300768,"score_gpt":0.345770585058885,"score_spread":0.33063588817058426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4384663251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.61528134,0.0002486566,0.38301644,0.0003166342,0.00045218552,0.00043158396,0.000018443756,0.000028935652,0.00020580155],"genre_scores_gemma":[0.7552129,0.00006693354,0.24311383,0.00081095676,0.0002390363,0.00011663343,0.00013761033,0.000074512405,0.0002276149],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996621,0.0013545298,0.00056884997,0.0007138521,0.0001642875,0.0005774759],"domain_scores_gemma":[0.99890596,0.00020658129,0.00018435031,0.00049264013,0.00011248697,0.000097956785],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017946274,0.00029089613,0.00040887474,0.00021462423,0.000100468416,0.000026684553,0.00049524795,0.00028811969,0.0000779696],"category_scores_gemma":[0.00073238544,0.00022818845,0.00023429506,0.0008941263,0.00012346987,0.0000041841486,0.00031460795,0.0002491242,0.000034774355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009652666,0.000029816261,0.000030367895,0.000025418163,0.000046408917,0.0000059998265,0.0002176779,0.00082238606,0.99198824,0.0016849819,0.0001906218,0.0048615816],"study_design_scores_gemma":[0.00033063383,0.0004399208,0.00003324381,0.000019798697,0.00001811643,0.0000032086034,0.0004528439,0.0003124053,0.9935697,0.0022389584,0.0023070113,0.00027420567],"about_ca_topic_score_codex":0.000026275238,"about_ca_topic_score_gemma":0.0000011038902,"teacher_disagreement_score":0.13993154,"about_ca_system_score_codex":0.000016680699,"about_ca_system_score_gemma":0.00008006271,"threshold_uncertainty_score":0.9305255},"labels":[],"label_agreement":null},{"id":"W4385336832","doi":"10.1016/j.jbc.2023.105107","title":"Development of a V5-tag–directed nanobody and its implementation as an intracellular biosensor of GPCR signaling","year":2023,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Ottawa","keywords":"G protein-coupled receptor; Intracellular; Biosensor; Cell biology; Chemistry; Signal transduction; Computational biology; Biology; Biochemistry","score_opus":0.028244756021278315,"score_gpt":0.2951589639404102,"score_spread":0.2669142079191319,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385336832","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991403,0.0005513223,0.00013996489,0.000018234847,0.000044584016,0.00006096717,0.000009837964,0.000007685367,0.000027102658],"genre_scores_gemma":[0.9956386,0.00025175966,0.003868067,0.000012967463,0.00011465708,0.0000020670198,0.00007398267,0.000008765125,0.000029148563],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885744,0.000043860073,0.00060466054,0.00017397046,0.00015824585,0.00016179553],"domain_scores_gemma":[0.9991099,0.000021805883,0.00047071636,0.00008040012,0.00021800045,0.00009916753],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005259716,0.00012443197,0.00025632934,0.000037484784,0.000043780306,0.00000839582,0.00013807631,0.00018874547,0.00014015789],"category_scores_gemma":[0.00011754414,0.00009525051,0.000086019856,0.000119319164,0.00003806979,0.0000056789745,0.0000657576,0.00009393736,8.7679973e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011617294,0.000051236424,0.00027385674,0.000053921438,0.0000729929,0.0000072411976,0.00013369723,0.000013787391,0.99727637,0.000011458527,0.00001629724,0.0019729948],"study_design_scores_gemma":[0.00044363036,0.00033726764,0.000284933,0.000038029284,0.00001563431,0.000036535013,0.0010395009,0.00004032047,0.99698377,0.00007248609,0.0005960994,0.00011177373],"about_ca_topic_score_codex":0.0000014330825,"about_ca_topic_score_gemma":3.1915243e-7,"teacher_disagreement_score":0.003728102,"about_ca_system_score_codex":0.000010433549,"about_ca_system_score_gemma":0.00009347826,"threshold_uncertainty_score":0.3884203},"labels":[],"label_agreement":null},{"id":"W4385349449","doi":"10.1038/s41598-023-39525-4","title":"Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Faculty of Medicine, McGill University; Courtois Foundation; Government of Canada; McGill University","keywords":"Induced pluripotent stem cell; Cell biology; Biology; Transcriptome; G protein-coupled receptor; Signal transduction; Kinase; Computational biology; Cell signaling; Myocyte; Cell; Embryonic stem cell; Gene expression; Genetics; Gene","score_opus":0.01615181151533872,"score_gpt":0.2357788479239675,"score_spread":0.21962703640862877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385349449","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972708,0.0015190099,0.00019408877,0.000019820602,0.0006975802,0.00018135349,0.0000018187638,0.000020483834,0.00009503884],"genre_scores_gemma":[0.99933684,0.000028389637,0.00022471842,0.000008704196,0.00007088031,0.000010829968,0.0001106094,0.000012624138,0.00019639284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99885774,0.000042238593,0.0002785656,0.0004321041,0.00019948129,0.00018987629],"domain_scores_gemma":[0.9994825,0.00001368821,0.0001210287,0.00026545368,0.000064948166,0.00005235556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010845221,0.000109568275,0.00018103965,0.00006621976,0.00034505228,0.000119396,0.00007990321,0.000056547764,0.000006105571],"category_scores_gemma":[0.00002572566,0.00008180953,0.000064385604,0.00015194067,0.00015946956,0.000008749895,0.00010665784,0.000061635335,3.4530234e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000076905635,0.000004002762,0.007144548,0.000052316213,0.000026011616,0.00001755723,0.00029486575,0.00011979287,0.9918396,0.000022162452,0.00010810385,0.00036335614],"study_design_scores_gemma":[0.00014125722,0.000039186343,0.00093458634,0.00003070515,0.000020689493,0.000069474794,0.00046511515,0.00022469042,0.9964943,0.00035690278,0.0011127507,0.00011034541],"about_ca_topic_score_codex":0.0000117081145,"about_ca_topic_score_gemma":0.000008652896,"teacher_disagreement_score":0.0062099616,"about_ca_system_score_codex":0.0000037895127,"about_ca_system_score_gemma":0.000035048844,"threshold_uncertainty_score":0.33360958},"labels":[],"label_agreement":null},{"id":"W4385379839","doi":"10.1038/s41467-023-40213-0","title":"Pathway selectivity in Frizzleds is achieved by conserved micro-switches defining pathway-determining, active conformations","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Supercomputer Centre, Linköpings Universitet; H. Lundbeck A/S; Innovative Medicines Initiative; Novo Nordisk Fonden; Vetenskapsrådet; Kungliga Tekniska Högskolan; Karolinska Institutet; Lundbeckfonden; Wenner-Gren Stiftelserna; Cancerfonden; National Science Council; Deutsche Forschungsgemeinschaft; European Commission; McGill University; National Institute of General Medical Sciences; Diamond Light Source; Novo Nordisk; European Federation of Pharmaceutical Industries and Associations","keywords":"Heterotrimeric G protein; Frizzled; G protein-coupled receptor; G protein; Biology; Mutagenesis; Smoothened; Signal transduction; Computational biology; Mutant; Genetics; Gene; Hedgehog signaling pathway","score_opus":0.016001851805778677,"score_gpt":0.2763021602291398,"score_spread":0.2603003084233611,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385379839","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937123,0.0017649964,0.00022604408,0.0012241099,0.0001170395,0.00029009834,0.00042669865,0.00007951941,0.0021591643],"genre_scores_gemma":[0.9947572,0.0005295989,0.0016122238,0.00065140345,0.000022790047,0.00011483033,0.0019794474,0.00002801126,0.00030453622],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988643,0.00015850295,0.00029171575,0.00027239625,0.00012367935,0.00028942863],"domain_scores_gemma":[0.99855435,0.00013452361,0.00014990981,0.000947115,0.00014446257,0.0000696353],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003677796,0.00018486682,0.00019145873,0.00011460727,0.00035852243,0.000051761424,0.000677348,0.00047834884,0.000029851935],"category_scores_gemma":[0.00022116827,0.0001942361,0.00009080307,0.00043449775,0.00008117356,0.00001854074,0.00036458363,0.0006940032,0.000037406666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018688284,0.00006956929,0.0020896047,0.0000068146005,0.00004414625,5.406833e-7,0.0007711843,0.000006869941,0.9885814,0.0005886047,0.0049356553,0.0028868883],"study_design_scores_gemma":[0.00056584005,0.00008742156,0.0026907502,0.000034889927,0.0000114987515,0.000007162304,0.0009586013,0.00067162246,0.91279,0.00019689683,0.081682965,0.0003023234],"about_ca_topic_score_codex":0.000037971415,"about_ca_topic_score_gemma":0.00048568766,"teacher_disagreement_score":0.07674731,"about_ca_system_score_codex":0.00003912225,"about_ca_system_score_gemma":0.00020774429,"threshold_uncertainty_score":0.7920718},"labels":[],"label_agreement":null},{"id":"W4385654875","doi":"10.1126/scisignal.adf2173","title":"Unraveling allostery within the angiotensin II type 1 receptor for Gα <sub>q</sub> and β-arrestin coupling","year":2023,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke; McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; National Institutes of Health; Université de Montréal; National Institute of General Medical Sciences; McGill University","keywords":"Allosteric regulation; Arrestin; Receptor; G protein-coupled receptor; Angiotensin II; Alanine scanning; Transmembrane domain; Functional selectivity; Biophysics; Cell biology; Biology; Coupling (piping); Signal transduction; Allosteric modulator; Mutagenesis; Chemistry; Mutant; Biochemistry; Gene; Materials science","score_opus":0.020479240453496302,"score_gpt":0.25634747057342805,"score_spread":0.23586823011993174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385654875","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.993279,0.0003765059,0.004851228,0.0002819734,0.00083931774,0.00030162765,0.0000075352355,0.000045517998,0.000017336599],"genre_scores_gemma":[0.99572515,0.00006560596,0.003393671,0.0002472745,0.00042339668,0.000017835719,0.000030948628,0.000030281477,0.000065845015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99837977,0.000022689526,0.00026347308,0.0005726037,0.00029053888,0.00047094075],"domain_scores_gemma":[0.99917215,0.0000747712,0.000121699755,0.00025703083,0.00025652794,0.00011784748],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023543255,0.0001754461,0.00014678943,0.00010655742,0.0011813061,0.00015059546,0.00032782345,0.000104280494,0.0000056761637],"category_scores_gemma":[0.0004872087,0.00013546314,0.00006859851,0.000628952,0.00027793346,0.00001701386,0.0002646349,0.000115923736,0.00001015892],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033774057,0.0000052615474,0.000056954093,0.00000937438,0.000011040895,8.742574e-7,0.00029329478,0.0074403104,0.990659,0.00020831848,0.0002159329,0.0010658741],"study_design_scores_gemma":[0.00018727918,0.00019831689,0.000026716601,0.000062681174,0.00001387368,0.0000065940917,0.0006539457,0.027076222,0.9705364,0.00040918778,0.0006235413,0.00020522284],"about_ca_topic_score_codex":0.000006872602,"about_ca_topic_score_gemma":0.0000048137276,"teacher_disagreement_score":0.02012257,"about_ca_system_score_codex":0.000017041506,"about_ca_system_score_gemma":0.00021060489,"threshold_uncertainty_score":0.9085771},"labels":[],"label_agreement":null},{"id":"W4385688465","doi":"10.1101/2023.08.09.552495","title":"Heart-on-a-chip model of immune-induced cardiac dysfunction reveals the role of free mitochondrial DNA and therapeutic effects of endothelial exosomes","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; St. Michael's Hospital; Toronto General Hospital; University Health Network; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Canadian Institutes of Health Research; Killam Trusts; University of Toronto; Canada Research Chairs","keywords":"Microvesicles; Mitochondrial DNA; Immune system; Endothelial dysfunction; Cardiac dysfunction; Mitochondrion; Medicine; Biology; Immunology; Cell biology; Cardiology; microRNA; Heart failure; Genetics; Gene","score_opus":0.012141682335438338,"score_gpt":0.21164330697532702,"score_spread":0.19950162463988869,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385688465","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945474,0.0025326216,0.00049421354,0.000028158442,0.0013003496,0.00077344314,0.00029447654,0.000025802043,0.0000035179164],"genre_scores_gemma":[0.99834645,0.00037562786,0.000632198,0.000024222189,0.00042588304,0.00010127276,9.0666373e-7,0.00008730695,0.0000061218384],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998078,0.00022558411,0.0005617422,0.0005611327,0.00030940675,0.000264142],"domain_scores_gemma":[0.9978605,0.00010405053,0.0005237221,0.0011859419,0.0002548264,0.000070974645],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042605336,0.0003530091,0.0006547261,0.00011417132,0.00007041332,0.00002308627,0.00040696905,0.0004903222,0.0000029827356],"category_scores_gemma":[0.00024212194,0.0002961447,0.00032654786,0.00012708132,0.00010445952,0.0000045176203,0.00037138132,0.00027712976,0.000001157245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015456944,0.000057739668,0.00037012275,0.00035414752,0.0003183823,4.0865382e-7,0.000019828967,0.00032095503,0.9978407,0.00053802173,0.000018393772,0.00000673523],"study_design_scores_gemma":[0.00056867267,0.0002966492,0.0022123565,0.0002759491,0.00014831575,6.5039174e-9,0.0000086333,0.00037073612,0.9956974,0.000101217636,0.000066509405,0.00025359128],"about_ca_topic_score_codex":0.00004947585,"about_ca_topic_score_gemma":8.545929e-7,"teacher_disagreement_score":0.0037990436,"about_ca_system_score_codex":0.000017066093,"about_ca_system_score_gemma":0.00022361439,"threshold_uncertainty_score":0.9999491},"labels":[],"label_agreement":null},{"id":"W4385691380","doi":"10.1088/1478-3975/aceecd","title":"Quantitative modeling of EGF receptor ligand discrimination via internalization proofreading","year":2023,"lang":"en","type":"article","venue":"Physical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Toronto Metropolitan University","keywords":"Internalization; Clathrin; Endocytosis; Ligand (biochemistry); Epidermal growth factor receptor; Cell biology; Endosome; Epidermal growth factor; Receptor; Biology; Biophysics; Chemistry; Biochemistry","score_opus":0.029496401123999885,"score_gpt":0.3156052024971973,"score_spread":0.28610880137319744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385691380","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7581169,0.000044810797,0.24146284,0.00003824029,0.0001048828,0.00008233952,0.000010203832,0.000017705555,0.00012208208],"genre_scores_gemma":[0.9984943,0.000048191836,0.0007638923,0.000020668314,0.00017307405,0.000017399258,0.00039241998,0.000013753879,0.00007626221],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993489,0.00005584535,0.00016033022,0.0002307112,0.000055760127,0.00014846325],"domain_scores_gemma":[0.9996803,0.00002092352,0.000077640114,0.000101958205,0.00008939345,0.000029785408],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012398789,0.0000933077,0.00014648514,0.000052495816,0.00003947116,0.0000059562267,0.00009745653,0.000077379555,0.000008292479],"category_scores_gemma":[0.000085779844,0.00007986849,0.000072582276,0.00012934451,0.00004067063,0.000005023768,0.00006775628,0.000047125737,0.00001942053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004955696,0.000035345536,0.00011960863,0.00001671233,0.000027639922,1.1386469e-7,0.0002373448,0.0015366569,0.9874173,0.008335848,0.00005268422,0.0021712277],"study_design_scores_gemma":[0.00014154274,0.00044187784,0.00001346241,0.000018927723,0.000009458978,4.2550408e-7,0.00010629538,0.17202887,0.81822693,0.008767314,0.00014993954,0.00009497567],"about_ca_topic_score_codex":0.000019478188,"about_ca_topic_score_gemma":0.0000034639825,"teacher_disagreement_score":0.24069895,"about_ca_system_score_codex":0.000007245398,"about_ca_system_score_gemma":0.000012906431,"threshold_uncertainty_score":0.32569426},"labels":[],"label_agreement":null},{"id":"W4385704160","doi":"10.1038/s41586-023-05995-9","title":"Intrinsic dopamine and acetylcholine dynamics in the striatum of mice","year":2023,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Institute of General Medical Sciences; Yale University; National Institutes of Health; York University","keywords":"Neuroscience; Striatum; Acetylcholine; Dopamine; Tonic (physiology); Midbrain; Glutamatergic; Cholinergic; Dopaminergic; Psychology; Biology; Glutamate receptor; Central nervous system; Endocrinology","score_opus":0.005507619236621197,"score_gpt":0.24632994527554924,"score_spread":0.24082232603892806,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385704160","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99781376,0.0011598445,0.00003873581,0.0005861272,0.00011427188,0.00008110842,0.00001959465,0.000004390234,0.00018217495],"genre_scores_gemma":[0.9988168,0.000422549,0.00014675621,0.00022014955,0.00010327302,0.0000031017637,0.0001279311,0.0000065720983,0.00015290767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99958235,0.000029222541,0.0000898657,0.00012372564,0.00007886396,0.00009599189],"domain_scores_gemma":[0.99978584,0.000015957421,0.000032180615,0.00012206252,0.000030275085,0.000013683799],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023896017,0.00005953206,0.000073293224,0.00003632724,0.00001846104,0.000007278804,0.000115229595,0.00039484183,0.0000048176075],"category_scores_gemma":[0.000078020574,0.000041563682,0.000025115585,0.00017926354,0.000017485103,0.0000013338823,0.000052146588,0.0003798403,8.8948156e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009342969,0.000034907724,0.0014265265,0.00004234137,0.000023841545,0.000006698156,0.00011647633,0.000045716544,0.9818042,0.0033438453,0.0025321392,0.010529856],"study_design_scores_gemma":[0.0029356696,0.00073681783,0.017155858,0.000091776375,0.000044970606,0.000049629754,0.0030666823,0.0037207983,0.926464,0.0020118891,0.043204747,0.00051713147],"about_ca_topic_score_codex":0.0000074050718,"about_ca_topic_score_gemma":0.00008171952,"teacher_disagreement_score":0.055340193,"about_ca_system_score_codex":0.000005054854,"about_ca_system_score_gemma":0.000013856779,"threshold_uncertainty_score":0.3045382},"labels":[],"label_agreement":null},{"id":"W4385875452","doi":"10.1101/2023.08.14.553154","title":"A non-canonical mechanism of GPCR activation","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Chemistry, Engineering and Medicine for Human Health, Stanford University; National Institutes of Health; National Science Foundation","keywords":"G protein-coupled receptor; Allosteric regulation; Intracellular; Mutagenesis; Mechanism (biology); Chemistry; Drug discovery; Function (biology); G protein; Computational biology; Signal transduction; Receptor; Cell biology; Biology; Biochemistry; Mutation; Gene; Physics","score_opus":0.016500979768904016,"score_gpt":0.23013888925328044,"score_spread":0.21363790948437641,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385875452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95594925,0.0001687459,0.041841634,0.0000850619,0.0011560293,0.00056285586,0.00012104462,0.00010244226,0.000012927697],"genre_scores_gemma":[0.9939126,0.0002492876,0.004829038,0.00008815006,0.0006227297,0.000114816256,0.000002866989,0.00015360584,0.000026901991],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99773115,0.000072564784,0.0005325642,0.00090744725,0.0003414398,0.0004148193],"domain_scores_gemma":[0.9979275,0.000019661802,0.00044482105,0.0010553201,0.0003851502,0.0001675451],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00050553685,0.0004237158,0.00047943386,0.00016401753,0.000085210755,0.00006141183,0.00051424804,0.0008756489,0.000052698182],"category_scores_gemma":[0.000164966,0.00046142627,0.0002555057,0.00023041293,0.00006045237,0.000006855215,0.00065120816,0.0004138284,0.00003217918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039421953,0.00006459019,0.00021521338,0.0001841797,0.00015614487,0.0000051023785,0.0000034623617,0.00011528132,0.99744606,0.001428237,0.0003412878,0.0000010310735],"study_design_scores_gemma":[0.00033646612,0.00012843987,0.002058355,0.00024541275,0.000053305477,6.8410384e-9,0.0000033547685,0.0003395699,0.9951558,0.000020163485,0.001189028,0.00047007218],"about_ca_topic_score_codex":0.000061548795,"about_ca_topic_score_gemma":0.0000024441833,"teacher_disagreement_score":0.037963346,"about_ca_system_score_codex":0.00004995186,"about_ca_system_score_gemma":0.0006054254,"threshold_uncertainty_score":0.99978375},"labels":[],"label_agreement":null},{"id":"W4386024113","doi":"10.1016/j.coph.2023.102377","title":"Discerning conformational dynamics and binding kinetics of GPCRs by 19F NMR","year":2023,"lang":"en","type":"review","venue":"Current Opinion in Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"College of Family Physicians of Canada; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Fluorine-19 NMR; G protein-coupled receptor; Molecular dynamics; Small molecule; Relaxation (psychology); Macromolecule; Nuclear magnetic resonance spectroscopy; Molecule; Computational chemistry; Biophysics; Stereochemistry; Receptor; Biochemistry; Organic chemistry; Biology","score_opus":0.07335087713908589,"score_gpt":0.40798109316550735,"score_spread":0.33463021602642146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386024113","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004624405,0.9930906,0.0010280376,0.000014697064,0.0044783056,0.00041923855,0.00046234945,0.00001047946,0.000033820175],"genre_scores_gemma":[0.00016421099,0.9947984,0.000054029155,0.0000049358105,0.00035792284,0.00007715791,0.0044286395,0.000038195118,0.00007647094],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.998532,0.00012838095,0.00065354834,0.00032079898,0.00011726693,0.00024803565],"domain_scores_gemma":[0.99932146,0.00006308242,0.00040786417,0.00009891178,0.00004003795,0.00006865896],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021751638,0.00026053007,0.00061733037,0.00018602352,0.000033455413,0.000013253675,0.00020238174,0.00027841592,0.000084929416],"category_scores_gemma":[0.000027680786,0.00024819933,0.00013529533,0.0001597393,0.00007871329,0.000004298946,0.00021793749,0.00028018458,0.00000816475],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003102244,0.0001827781,0.000045507575,0.031311132,0.0003230002,8.444867e-7,0.00007797934,0.00007661319,0.012694808,0.0009194039,0.023161506,0.9311754],"study_design_scores_gemma":[0.00042477172,0.000110764064,8.829825e-7,0.002278083,0.00008680885,0.000010335795,0.00002730441,0.000624903,0.0011775233,0.00001653637,0.9949619,0.00028018001],"about_ca_topic_score_codex":0.0000019267532,"about_ca_topic_score_gemma":6.9239724e-7,"teacher_disagreement_score":0.9718004,"about_ca_system_score_codex":0.00004843106,"about_ca_system_score_gemma":0.000081272236,"threshold_uncertainty_score":0.999997},"labels":[],"label_agreement":null},{"id":"W4386090061","doi":"10.1021/acschembio.3c00319","title":"G Protein-Biased Agonists for Intracellular Angiotensin Receptors Promote Collagen Secretion in Myofibroblasts","year":2023,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Institut National de la Recherche Scientifique; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Intracellular; Receptor; Chemistry; G protein-coupled receptor; Secretion; Angiotensin II; Functional selectivity; Tyrosine; Cell biology; Peptide; Amino acid; Biochemistry; Small molecule; Biology","score_opus":0.012986017742260743,"score_gpt":0.2506338083824487,"score_spread":0.23764779064018796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386090061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967022,0.00014071543,0.0015699497,0.00045435704,0.00020533265,0.0007964003,0.000031323027,0.000052048308,0.000047661604],"genre_scores_gemma":[0.9938002,0.000040025814,0.0031703794,0.00011720886,0.00032231185,0.00019988262,0.001853413,0.000039700826,0.00045685348],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984905,0.000074288946,0.00031883887,0.00055875565,0.00007184993,0.00048573472],"domain_scores_gemma":[0.999455,0.000031555748,0.00009333351,0.00024153029,0.00008574123,0.000092874994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036606868,0.00020534442,0.0002557547,0.00008161952,0.00005605497,0.000017035418,0.00019643726,0.00053355884,0.000045445144],"category_scores_gemma":[0.00031880455,0.00019683025,0.00011812839,0.000264446,0.000087291046,0.0000035696783,0.00011268611,0.00008688926,0.000030135194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018982541,0.000032552136,0.000105267674,0.000023396373,0.000026383113,0.0000029609118,0.00003711035,0.000011985708,0.99550855,0.00019502697,0.0013068197,0.002560135],"study_design_scores_gemma":[0.0007158522,0.000334226,0.000020077385,0.000027871762,0.000006870165,0.0000042463926,0.000024222112,0.00032705066,0.9667067,0.0012479036,0.030347422,0.00023757058],"about_ca_topic_score_codex":0.000011731015,"about_ca_topic_score_gemma":0.0000064401897,"teacher_disagreement_score":0.029040601,"about_ca_system_score_codex":0.000032282052,"about_ca_system_score_gemma":0.000061538,"threshold_uncertainty_score":0.8026505},"labels":[],"label_agreement":null},{"id":"W4386366735","doi":"10.1016/j.jbc.2023.105218","title":"G protein–receptor kinases 5/6 are the key regulators of G protein–coupled receptor 35–arrestin interactions","year":2023,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Biotechnology and Biological Sciences Research Council; Directorate for Biological Sciences; Fonds De La Recherche Scientifique - FNRS; Fonds National de la Recherche Luxembourg; Commonwealth Scholarship Commission; UK Research and Innovation","keywords":"G protein-coupled receptor kinase; Arrestin; Cell biology; Receptor; Kinase; Chemistry; Key (lock); 5-HT5A receptor; G protein-coupled receptor; Biology; Biochemistry; Ecology","score_opus":0.023800261971449976,"score_gpt":0.2585547816804337,"score_spread":0.23475451970898376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386366735","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9983188,0.0004415155,0.00011559084,0.00049720716,0.00022420476,0.00022582972,0.00003000065,0.000019373081,0.00012751517],"genre_scores_gemma":[0.997348,0.00013109436,0.0006866328,0.000038910373,0.00083272066,0.00003364418,0.00005065933,0.000020319547,0.00085803797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984211,0.00010362172,0.0006703514,0.00026186462,0.00026069145,0.00028239813],"domain_scores_gemma":[0.9983707,0.00005809643,0.00085364946,0.00028839923,0.0002947962,0.00013437888],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005943208,0.00022005074,0.00035830043,0.00003791947,0.00012520068,0.000029667179,0.0004681457,0.000266536,0.00054343126],"category_scores_gemma":[0.00096665387,0.00013239459,0.00035050308,0.00025157147,0.00017589967,0.000008229063,0.0001529503,0.0003528095,0.000013658157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023557233,0.00008793261,0.00095302094,0.00004702603,0.0000836388,0.00000552607,0.000023438439,0.00003082296,0.9968116,0.000016635011,0.001148826,0.00055593415],"study_design_scores_gemma":[0.00033180002,0.00030276112,0.00036676726,0.00022150703,0.000014725423,0.000030287996,0.0005110813,0.000032361626,0.98512614,0.00014749158,0.012746102,0.00016899193],"about_ca_topic_score_codex":0.0000036629265,"about_ca_topic_score_gemma":5.561025e-7,"teacher_disagreement_score":0.011685505,"about_ca_system_score_codex":0.000027548356,"about_ca_system_score_gemma":0.00009561265,"threshold_uncertainty_score":0.5950191},"labels":[],"label_agreement":null},{"id":"W4386791193","doi":"10.1101/2023.09.11.557127","title":"Discovery of a functionally selective serotonin 5-HT <sub>1A</sub> receptor agonist for the treatment of pain","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Julius-Maximilians-Universität Würzburg; Deutsche Forschungsgemeinschaft; Université de Montréal; Studienstiftung des Deutschen Volkes; Boehringer Ingelheim Stiftung; European Commission; Japan Society for the Promotion of Science; Verband der Chemischen Industrie","keywords":"Agonist; G protein-coupled receptor; Serotonin; 5-HT receptor; Functional selectivity; Chemistry; Receptor; Pharmacology; Partial agonist; Neuroscience; Medicine; Biology; Biochemistry","score_opus":0.015147271560825354,"score_gpt":0.2217538939395963,"score_spread":0.20660662237877095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386791193","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9560756,0.0018466972,0.03758968,0.00012239625,0.0011486472,0.0018856471,0.0012766747,0.000052867832,0.0000017846637],"genre_scores_gemma":[0.99383974,0.0020152412,0.002144743,0.000050300278,0.0006784394,0.0010741643,0.000013478133,0.00014327647,0.00004059445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99775,0.00018549793,0.00058009714,0.00082476676,0.0002746486,0.00038499103],"domain_scores_gemma":[0.997675,0.00017977768,0.0005983536,0.00086151174,0.0006030201,0.00008235893],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007834773,0.00047336635,0.0005594758,0.000107980486,0.0001611357,0.00007131871,0.00037976407,0.00049809896,0.000008142392],"category_scores_gemma":[0.00022978718,0.00038817953,0.0004893049,0.00023777236,0.00013362578,0.000008704848,0.0001645633,0.0001724059,0.0000042806396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032037878,0.00023745844,0.00056773715,0.00023864857,0.0007873431,0.0000011564638,0.000014542111,0.00045374336,0.9964981,0.000230342,0.00063027715,0.000020253095],"study_design_scores_gemma":[0.00059035124,0.0010112424,0.002196292,0.00015048002,0.00017439434,7.852205e-9,0.000014868012,0.00025755417,0.9907328,0.0000067288097,0.0044883615,0.0003769562],"about_ca_topic_score_codex":0.00005168145,"about_ca_topic_score_gemma":0.000015690828,"teacher_disagreement_score":0.037764158,"about_ca_system_score_codex":0.00011402275,"about_ca_system_score_gemma":0.0007365193,"threshold_uncertainty_score":0.999857},"labels":[],"label_agreement":null},{"id":"W4386929819","doi":"10.1101/2023.09.19.558526","title":"Serotonin predictively encodes value","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"Government of Ontario","keywords":"Surprise; Serotonergic; Salience (neuroscience); Reinforcement learning; Neuroscience; Psychology; Population; Tonic (physiology); Cognitive psychology; Computer science; Serotonin; Artificial intelligence; Communication; Biology","score_opus":0.01586337429953945,"score_gpt":0.22799388361079753,"score_spread":0.2121305093112581,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386929819","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97561604,0.001039365,0.019009821,0.00013208679,0.0022717777,0.0009943114,0.00048417298,0.00042050958,0.000031903393],"genre_scores_gemma":[0.98966104,0.00065263064,0.007574739,0.00017027637,0.0012788312,0.00033099193,0.0000031118548,0.00025355874,0.00007482539],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969577,0.00016654494,0.00049209874,0.0013573236,0.00039185252,0.0006344788],"domain_scores_gemma":[0.997797,0.000023377354,0.0003264411,0.0012324316,0.0003459452,0.0002748011],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00062788394,0.00060766935,0.00048195434,0.00016632752,0.00018153587,0.00017372427,0.00072246196,0.0009671119,0.000054920944],"category_scores_gemma":[0.00022896183,0.0006576351,0.00027797703,0.00023621408,0.00009668957,0.000008343609,0.00093110575,0.00058015576,0.000108499735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035541507,0.00004904312,0.0020043077,0.00015422405,0.00022511302,0.000022767732,0.000004524857,0.0007172246,0.9951886,0.00071165187,0.00088601466,9.867221e-7],"study_design_scores_gemma":[0.00033572022,0.00013142166,0.008798889,0.0002369464,0.000075959055,1.6371647e-8,0.0000031295783,0.0005747605,0.9814385,0.000015522308,0.0076445867,0.0007445339],"about_ca_topic_score_codex":0.000048759317,"about_ca_topic_score_gemma":0.0000026752068,"teacher_disagreement_score":0.014044982,"about_ca_system_score_codex":0.0000708523,"about_ca_system_score_gemma":0.0005795872,"threshold_uncertainty_score":0.9995875},"labels":[],"label_agreement":null},{"id":"W4386998234","doi":"10.31083/j.rcm2409264","title":"Status of β1-Adrenoceptor Signal Transduction System in Cardiac Hypertrophy and Heart Failure","year":2023,"lang":"en","type":"review","venue":"Reviews in Cardiovascular Medicine","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"","keywords":"Pressure overload; Heart failure; Muscle hypertrophy; Internal medicine; Medicine; Volume overload; Cardiology; Downregulation and upregulation; Signal transduction; Cardiac function curve; Endocrinology; Cardiac hypertrophy; Cell biology; Chemistry; Biology","score_opus":0.03661843132512417,"score_gpt":0.2957154345178771,"score_spread":0.2590970031927529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386998234","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017533838,0.9970793,0.0003375062,0.0000068669733,0.00052301725,0.0017836273,0.000038974988,0.000013989446,0.000041345582],"genre_scores_gemma":[0.0002071201,0.99776715,0.00041627468,0.000008442971,0.0008888218,0.0002885263,0.0003082326,0.000094823336,0.000020614518],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9955753,0.0012180553,0.0014525807,0.00083466625,0.00043203024,0.00048737237],"domain_scores_gemma":[0.9986891,0.00004890744,0.00027682772,0.00076143886,0.000064297856,0.00015941828],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0031688286,0.0005456403,0.0053520743,0.00035876423,0.00003158105,0.00000829033,0.00019657188,0.0005364114,0.000047999263],"category_scores_gemma":[0.00016074933,0.0004091277,0.0018338879,0.00065572246,0.00010949473,0.000005497784,0.00007434,0.00038973964,0.000010247236],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011143866,0.000020928379,0.000023688683,0.07354579,0.0011647847,0.000020073116,0.00009535088,0.000027670627,0.003332855,0.000022239054,0.00048672408,0.92124873],"study_design_scores_gemma":[0.00044741412,0.00016954694,0.000006658825,0.035363395,0.0012049373,0.000054712786,0.00016252093,0.0000026829434,0.00024937876,0.0000021503859,0.9620062,0.00033037673],"about_ca_topic_score_codex":0.00018285925,"about_ca_topic_score_gemma":0.000013035201,"teacher_disagreement_score":0.9615195,"about_ca_system_score_codex":0.00012021877,"about_ca_system_score_gemma":0.00016226308,"threshold_uncertainty_score":0.9998361},"labels":[],"label_agreement":null},{"id":"W4387003010","doi":"10.1139/cjpp-2023-0153","title":"Thyroid hormone induces restrictive cardiomyopathy in β1-adrenoceptor knockout mice","year":2023,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Ministério da Saúde; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Internal medicine; Endocrinology; Medicine; Ejection fraction; Angiotensin II; Cardiomyopathy; Thyroid; Heart failure; Hormone; Receptor","score_opus":0.03022539979146548,"score_gpt":0.30626043003947884,"score_spread":0.27603503024801335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387003010","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.087796696,0.91031206,0.000005835018,0.000031467316,0.0014388853,0.00025601737,0.00009910943,0.0000030897545,0.000056847177],"genre_scores_gemma":[0.020712985,0.9772951,0.000038003087,0.00013857389,0.0015314195,0.000027409533,0.000090884394,0.000053132724,0.000112512615],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99777687,0.00056142727,0.0006787166,0.0004041812,0.00006604574,0.0005127472],"domain_scores_gemma":[0.998696,0.0001029676,0.0005307928,0.00012910648,0.000121408084,0.0004196889],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046947677,0.00036844634,0.0013156924,0.0005613097,0.00011987821,0.000013836737,0.00040292804,0.00077348266,0.00024377556],"category_scores_gemma":[0.00006317824,0.00032359603,0.00033478532,0.00028041028,0.00023476493,0.000008287319,0.000069121816,0.00078892487,0.00001573968],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015094601,0.000044224627,0.000008053838,0.0022214116,0.0015786854,0.00051939447,0.0004141832,0.000047963902,0.9018197,0.000052237603,0.01612511,0.077018104],"study_design_scores_gemma":[0.001002548,0.0012432587,0.000047905298,0.00065591757,0.0007058073,0.00044423147,0.00018445702,0.0000018899684,0.01983768,0.0003142646,0.9749579,0.0006041551],"about_ca_topic_score_codex":0.00038619473,"about_ca_topic_score_gemma":0.00036484978,"teacher_disagreement_score":0.9588328,"about_ca_system_score_codex":0.000081114275,"about_ca_system_score_gemma":0.0018894365,"threshold_uncertainty_score":0.9999216},"labels":[],"label_agreement":null},{"id":"W4387004153","doi":"10.1117/1.nph.10.4.044406","title":"Shining light on the noradrenergic system","year":2023,"lang":"en","type":"review","venue":"Neurophotonics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada; Brain and Behavior Research Foundation","keywords":"Locus coeruleus; Neuroscience; Norepinephrine; Calcium imaging; Brain function; Computer science; Biology; Chemistry; Central nervous system; Calcium; Dopamine","score_opus":0.05415169311221083,"score_gpt":0.29302553384351604,"score_spread":0.23887384073130521,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387004153","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023779264,0.9953824,0.000023922434,0.000021881784,0.001445409,0.0005269128,0.00003648278,0.00007787785,0.0022472981],"genre_scores_gemma":[0.00011378469,0.99750954,0.000026836775,0.00014246834,0.00048694637,0.00013360726,0.00010489892,0.00018013752,0.0013017902],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980941,0.00026242386,0.00042438685,0.0006492949,0.00024047837,0.00032934465],"domain_scores_gemma":[0.99864733,0.00007837188,0.00026777823,0.00089185877,0.000037497688,0.00007717688],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033365987,0.00042119718,0.000708149,0.00006678763,0.00018544398,0.00008833226,0.0006419448,0.00037262618,0.00002941822],"category_scores_gemma":[0.00008410865,0.00026115993,0.0005640055,0.00024285115,0.000020264333,9.0625736e-7,0.00021718121,0.00041727556,0.00035184875],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012064778,0.00028101762,7.0352104e-7,0.057605237,0.0027047626,0.0012894203,0.00020403574,0.00095161947,0.044571143,0.039798178,0.045249317,0.8072239],"study_design_scores_gemma":[0.000049940216,0.00015079176,1.77155e-8,0.0026466837,0.00014327496,0.0000420455,0.000017128268,0.00006207226,0.0022661597,0.0000043114724,0.99435043,0.00026712593],"about_ca_topic_score_codex":0.0000029034181,"about_ca_topic_score_gemma":0.000001509259,"teacher_disagreement_score":0.94910115,"about_ca_system_score_codex":0.000032299595,"about_ca_system_score_gemma":0.00016612094,"threshold_uncertainty_score":0.9999841},"labels":[],"label_agreement":null},{"id":"W4387007475","doi":"10.1139/cjpp-2023-0206","title":"Considerations for choosing an optimal animal model of cardiovascular disease","year":2023,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Disease; Medicine; Animal model; Intensive care medicine; Diabetes mellitus; Myocardial ischemia; Bioinformatics; Ischemia; Cardiology; Pathology; Internal medicine; Biology; Endocrinology","score_opus":0.0834690837001651,"score_gpt":0.3378822389318733,"score_spread":0.2544131552317082,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387007475","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01025035,0.987577,0.0008918453,0.000021118725,0.0005192381,0.0003311228,0.00040286372,0.0000021708515,0.000004263757],"genre_scores_gemma":[0.021569066,0.9760607,0.0011253877,0.000092185655,0.00090648053,0.000035219105,0.00013673096,0.000050375533,0.000023839548],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99871093,0.00021967711,0.00047863138,0.00026834893,0.000046697434,0.000275724],"domain_scores_gemma":[0.9988015,0.00007181937,0.00031272983,0.00014625273,0.00019695895,0.00047070876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036976647,0.00021531894,0.0009468986,0.00018345803,0.00015024647,0.0000098503815,0.0001601055,0.00030087074,0.00012816355],"category_scores_gemma":[0.00006922868,0.00019603534,0.0005989991,0.000049102455,0.00016437109,0.000007680401,0.000023824932,0.00020748179,5.938382e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006126363,0.00014075977,0.00000258634,0.018893525,0.01615015,0.00017194067,0.0003202036,0.09639163,0.78308636,0.0014234228,0.0077945944,0.07501221],"study_design_scores_gemma":[0.002143632,0.002518052,0.0000028868346,0.0012987923,0.012421427,0.00031764377,0.000071284696,0.0062227347,0.045310453,0.0034425796,0.92509454,0.0011559484],"about_ca_topic_score_codex":0.000034657798,"about_ca_topic_score_gemma":0.000032124626,"teacher_disagreement_score":0.9173,"about_ca_system_score_codex":0.000019593357,"about_ca_system_score_gemma":0.0022991642,"threshold_uncertainty_score":0.7994089},"labels":[],"label_agreement":null},{"id":"W4387079644","doi":"10.1016/j.jbc.2023.105293","title":"Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor","year":2023,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"U.S. National Library of Medicine; National Institute of Mental Health; Japan Science and Technology Agency; National Institute on Drug Abuse; Japan Society for the Promotion of Science; University of California, San Diego; National Cancer Institute; National Institutes of Health; Japan Agency for Medical Research and Development","keywords":"G protein-coupled receptor; Arrestin; G protein-coupled receptor kinase; Cell biology; Biology; Internalization; G protein; Protein kinase A; Beta adrenergic receptor kinase; HEK 293 cells; Signal transduction; Gene silencing; Kinase; Receptor; Gene; Biochemistry","score_opus":0.019592633952470358,"score_gpt":0.2583155264950673,"score_spread":0.23872289254259693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387079644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9868239,0.0009932347,0.011564667,0.0001572079,0.00009712133,0.0001780306,0.00016336121,0.000011247907,0.000011192751],"genre_scores_gemma":[0.99265724,0.00083859364,0.004966582,0.000059928003,0.00047302534,0.000033147335,0.0002513019,0.000020240554,0.00069990946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989,0.000016436405,0.00037095888,0.00032843326,0.000115655814,0.00026854782],"domain_scores_gemma":[0.99914986,0.00010164649,0.00032964046,0.000115354196,0.0001825828,0.00012089557],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048571447,0.00017564523,0.00027729076,0.000018013106,0.00015689517,0.000036445672,0.0001377583,0.00031545642,0.00009002174],"category_scores_gemma":[0.0002928463,0.00012737136,0.00017099325,0.00007105193,0.000053844706,0.000008414061,0.00006607577,0.00010144606,7.4282445e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00045412962,0.00004182906,0.0005509813,0.00005605614,0.000034084424,6.124121e-7,0.000018764325,0.00008576848,0.9879682,0.000002234223,0.010363935,0.0004233952],"study_design_scores_gemma":[0.0007901072,0.00041001532,0.00007615123,0.00005579425,0.000020922584,0.000016694514,0.000069591406,0.0017620536,0.9882834,0.00041838447,0.007922136,0.0001747399],"about_ca_topic_score_codex":0.0000014398361,"about_ca_topic_score_gemma":8.531056e-8,"teacher_disagreement_score":0.0065980847,"about_ca_system_score_codex":0.000020103034,"about_ca_system_score_gemma":0.00003839034,"threshold_uncertainty_score":0.5194053},"labels":[],"label_agreement":null},{"id":"W4387241943","doi":"10.1007/s13311-023-01436-7","title":"D1R-5-HT2AR Uncoupling Reduces Depressive Behaviours via HDAC Signalling","year":2023,"lang":"en","type":"article","venue":"Neurotherapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Sanming Project of Medicine in Shenzhen; Shenzhen-Hong Kong Institute of Brain Science; National Natural Science Foundation of China","keywords":"Dopamine; Dopamine receptor D2; CREB; Antidepressant; Medicine; Pharmacology; Neuroscience; Biology; Internal medicine; Biochemistry; Transcription factor","score_opus":0.024501476230572864,"score_gpt":0.2771207227478541,"score_spread":0.25261924651728124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387241943","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98911005,0.0004860044,0.009103593,0.000113099886,0.0005474105,0.00022645133,0.000013172408,0.0001093675,0.00029085248],"genre_scores_gemma":[0.9968966,0.00039275072,0.0008026893,0.00062212464,0.000464671,0.000029280654,0.00008528188,0.000093304785,0.0006132649],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986168,0.00005300638,0.0002436118,0.00045708095,0.00022633585,0.00040313104],"domain_scores_gemma":[0.9994137,0.000026917478,0.00010116702,0.0002781963,0.00008126304,0.000098711935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018043067,0.00022124298,0.00016676656,0.00007881774,0.00018791686,0.0000595856,0.00027403995,0.0001844395,0.00007425624],"category_scores_gemma":[0.000018532373,0.00022079986,0.00013231544,0.0002143635,0.000047035654,0.000005591539,0.000068713794,0.00016854145,0.000038861694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027877155,0.000026053682,0.00044311298,0.0000060952393,0.00004165464,0.000013308199,0.00008242591,0.002534586,0.9890532,0.00003100238,0.00016969324,0.0075710043],"study_design_scores_gemma":[0.0003181216,0.000215791,0.00014260733,0.00001731344,0.00003726863,0.0000115327575,0.00008046029,0.0031408567,0.988565,0.000250805,0.006948549,0.00027168845],"about_ca_topic_score_codex":0.000011320207,"about_ca_topic_score_gemma":0.0000053935937,"teacher_disagreement_score":0.008300904,"about_ca_system_score_codex":0.000009599249,"about_ca_system_score_gemma":0.000046554127,"threshold_uncertainty_score":0.9003957},"labels":[],"label_agreement":null},{"id":"W4387294942","doi":"10.5281/zenodo.8401216","title":"Investigating the Aryl Hydrocarbon Receptor Agonist/Antagonist Conformational Switch using Well-Tempered Metadynamics Simulations input and output files","year":2023,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Metadynamics; Agonist; Aryl; Chemistry; Antagonist; Hydrocarbon; Aryl hydrocarbon receptor; Stereochemistry; Combinatorial chemistry; Computer science; Receptor; Computational chemistry; Organic chemistry; Molecular dynamics; Biochemistry","score_opus":0.035374124844672304,"score_gpt":0.2538952234895455,"score_spread":0.2185210986448732,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387294942","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99067163,0.000085645486,0.004698876,0.00047698483,0.00012474204,0.00034487678,0.0002736144,0.00018512321,0.0031385287],"genre_scores_gemma":[0.99346775,0.00008471768,0.0006013852,0.00014686886,0.00017592397,9.269446e-8,0.0048122816,0.00035944025,0.00035156243],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99883956,0.00012144677,0.00025422667,0.00028994598,0.00023729783,0.00025752163],"domain_scores_gemma":[0.9992706,0.000024854595,0.00011999795,0.00025627378,0.0002233907,0.0001048513],"candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.00052230275,0.00013680555,0.00010935233,0.0000983702,0.0024026604,0.0005255521,0.00036206678,0.00008515953,0.00063433487],"category_scores_gemma":[0.0003506609,0.00012153943,0.00004608276,0.0003180017,0.00016185382,0.000026305075,0.0005050406,0.00015541897,0.00025973006],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022796337,0.00002387206,0.00002530168,0.00004331207,0.000083099214,0.0000011535903,0.00079602294,0.006604611,0.97468764,0.0020041438,0.009568528,0.0061395047],"study_design_scores_gemma":[0.0008074948,0.00024104645,0.00035042994,0.00006399984,0.000048999816,0.00008894616,0.0019772532,0.2105201,0.069770545,0.00053718727,0.71511286,0.00048113393],"about_ca_topic_score_codex":0.0000166523,"about_ca_topic_score_gemma":7.465009e-7,"teacher_disagreement_score":0.9049171,"about_ca_system_score_codex":0.00003335044,"about_ca_system_score_gemma":0.000011648088,"threshold_uncertainty_score":0.99889606},"labels":[],"label_agreement":null},{"id":"W4387429464","doi":"10.31234/osf.io/yvp3z","title":"Machine Learning to Detect Schedules Using Spatiotemporal Data of Behavior: A Proof of Concept","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institut universitaire en santé mentale de Montréal; Institut Universitaire en Santé Mentale de Québec","funders":"","keywords":"Stimulus (psychology); Computer science; Artificial intelligence; Machine learning; Artificial neural network; Psychology; Cognitive psychology","score_opus":0.09007733188157308,"score_gpt":0.33443649223606536,"score_spread":0.2443591603544923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387429464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8046145,0.00081131485,0.19332056,0.000015584654,0.00025256252,0.0005155384,0.0004159388,0.00001925998,0.00003478164],"genre_scores_gemma":[0.93014055,0.00003819616,0.06776688,0.000010269143,0.000114987975,0.000016088545,0.0016516153,0.000050129212,0.00021129048],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984571,0.00008512736,0.0004711381,0.000596553,0.00020841422,0.00018167883],"domain_scores_gemma":[0.9985817,0.000010717975,0.00033609557,0.000856173,0.00014750005,0.000067780944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003990231,0.00021719976,0.0003841188,0.000092160786,0.000035513036,0.0000164494,0.0005966915,0.00031517245,0.00009540148],"category_scores_gemma":[0.00016113152,0.00020761447,0.00011603248,0.00007963836,0.00004648499,0.0000026186756,0.002327352,0.00023452804,8.578473e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042667754,0.00003367011,0.0012152625,0.00014989788,0.00009745108,0.0000020978896,0.00005861037,0.01671525,0.9748085,0.000027754188,0.00003072724,0.0068181064],"study_design_scores_gemma":[0.00016791222,0.0002486242,0.000054975724,0.00014053026,0.00007171826,0.000001688632,0.00008837557,0.010078329,0.98850286,0.000088607965,0.00033021966,0.00022617736],"about_ca_topic_score_codex":0.0009745307,"about_ca_topic_score_gemma":0.00013271465,"teacher_disagreement_score":0.12555367,"about_ca_system_score_codex":0.000010607873,"about_ca_system_score_gemma":0.00017430267,"threshold_uncertainty_score":0.84662724},"labels":[],"label_agreement":null},{"id":"W4387454755","doi":"10.1038/s41467-023-41893-4","title":"GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Government of Canada; Robert Bosch Stiftung; Lundbeckfonden; Karolinska Institutet; European Commission; European Federation of Pharmaceutical Industries and Associations; McGill University; Alexander S. Onassis Public Benefit Foundation; Vetenskapsrådet; Svenska Sällskapet för Medicinsk Forskning; Foundation for the National Institutes of Health","keywords":"Incretin; Drug reaction; Drug; Medicine; Adverse effect; Pharmacology; Chemistry; Bioinformatics; Computational biology; Biology; Endocrinology; Diabetes mellitus; Type 2 diabetes","score_opus":0.012392156167189118,"score_gpt":0.2830395108893407,"score_spread":0.27064735472215157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387454755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99164677,0.00067684456,0.00069299707,0.0050407983,0.00010730514,0.00038047007,0.00008833977,0.00004821408,0.0013182844],"genre_scores_gemma":[0.993977,0.00019223936,0.0046533435,0.0002983846,0.00005848158,0.00003945164,0.00028130444,0.000021272772,0.00047853668],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989993,0.00022978896,0.00021631931,0.0002029072,0.00017177017,0.00017993095],"domain_scores_gemma":[0.99787897,0.00018244924,0.0001410284,0.0014142827,0.00032033125,0.00006296826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007815609,0.000117143405,0.00013073484,0.00005715078,0.00031955913,0.000015380007,0.00077136955,0.00018528415,0.00002793335],"category_scores_gemma":[0.00031914812,0.00008705629,0.000085030275,0.000521086,0.00009420248,0.000004418268,0.00036154865,0.00044018312,0.000013769783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034908444,0.00005937547,0.0018046276,0.000007910727,0.00009079026,2.6512154e-7,0.0003819676,0.0006715718,0.98970544,0.0020070977,0.0048822383,0.00035379652],"study_design_scores_gemma":[0.000606494,0.00028669235,0.0084413765,0.00008427297,0.0001436112,0.0000041451744,0.003968973,0.00065604906,0.7868759,0.0004119412,0.1980479,0.00047265587],"about_ca_topic_score_codex":0.00005727929,"about_ca_topic_score_gemma":0.000592316,"teacher_disagreement_score":0.20282957,"about_ca_system_score_codex":0.000025268004,"about_ca_system_score_gemma":0.000085902095,"threshold_uncertainty_score":0.35500523},"labels":[],"label_agreement":null},{"id":"W4387665142","doi":"10.1073/pnas.2303794120","title":"Signal transduction at GPCRs: Allosteric activation of the ERK MAPK by β-arrestin","year":2023,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; Sarnoff Cardiovascular Research Foundation; McGill University; Howard Hughes Medical Institute","keywords":"G protein-coupled receptor; Arrestin; Allosteric regulation; Cell biology; Signal transduction; Autophosphorylation; Scaffold protein; Phosphorylation; Effector; Signal transducing adaptor protein; Biology; MAPK/ERK pathway; Chemistry; Protein kinase A; Receptor; Biochemistry","score_opus":0.02934238630923239,"score_gpt":0.2746360205572852,"score_spread":0.2452936342480528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387665142","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982028,0.000050400424,0.000010633119,0.0011660297,0.00003068074,0.00011237245,0.00001351945,0.0000037776922,0.00040975635],"genre_scores_gemma":[0.9992775,0.000028179116,0.00018687228,0.00008417142,0.00006539869,0.000006360331,0.0000012663321,0.0000034998059,0.00034675925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99898064,0.000008008503,0.00019647149,0.00016329614,0.0005588188,0.00009274534],"domain_scores_gemma":[0.99956447,0.000016564225,0.00027103827,0.000008364774,0.00012536209,0.000014176128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006239745,0.0000612097,0.00007280089,0.000044542103,0.0001405817,0.0000073634146,0.00040451216,0.00007735371,0.000028356826],"category_scores_gemma":[0.00012172885,0.000037426853,0.00007295405,0.00046077455,0.00025727492,0.000018135734,0.000096736534,0.000057419056,5.3105816e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013457398,0.000010966463,0.00047207435,0.000022299815,0.000008185797,3.08631e-10,0.000058337075,0.00021115648,0.9966158,0.00053484,0.0018272517,0.000225613],"study_design_scores_gemma":[0.000084311934,0.00004711341,0.0040440946,0.00003800933,0.0000052460637,0.0000013638165,0.00009838266,0.00033742315,0.99196553,0.0028088428,0.0005268131,0.000042872405],"about_ca_topic_score_codex":0.0000032241362,"about_ca_topic_score_gemma":3.5844995e-8,"teacher_disagreement_score":0.004650291,"about_ca_system_score_codex":0.000011451853,"about_ca_system_score_gemma":0.00001947274,"threshold_uncertainty_score":0.15262227},"labels":[],"label_agreement":null},{"id":"W4387934405","doi":"10.1016/j.jcjd.2023.10.223","title":"TRENDS IN A1C LEVELS IN INDIVIDUALS TESTED AT COMMUNITY PHARMACIES","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Pharmacy; Medical prescription; Community pharmacy; Family medicine; Environmental health; Gerontology; Pharmacology","score_opus":0.0417013556821353,"score_gpt":0.2792633204811508,"score_spread":0.23756196479901553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387934405","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987273,0.00060264417,0.0000010600473,0.00017582306,0.00015794979,0.000028991692,0.00005133607,0.0000021051858,0.00025278135],"genre_scores_gemma":[0.99938536,0.000014672998,0.0000453963,0.00016858995,0.00006724373,0.0000023670984,0.000044280263,0.000012826037,0.0002592509],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9990929,0.00016178393,0.00026979757,0.00007573376,0.00007884848,0.00032095512],"domain_scores_gemma":[0.9994999,0.00003655586,0.00009386222,0.00011042315,0.000046006924,0.00021323508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00075857405,0.000094164956,0.00017087486,0.00056704157,0.00008393922,0.000026171465,0.00023355761,0.00008912845,0.00021383436],"category_scores_gemma":[0.00013160311,0.00009219535,0.00006730592,0.00040620982,0.000044319106,0.0000074204618,0.00003360839,0.00022417722,0.000005265532],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000013241042,0.00001290747,0.57088506,0.000009419603,0.000033179356,0.000012562201,0.0005831674,0.00029472116,0.41988385,0.0000072577686,0.0036804634,0.0045961034],"study_design_scores_gemma":[0.001099505,0.0002441963,0.6397397,0.0000988535,0.000011753977,0.000005463179,0.0005938976,0.00005715307,0.3482979,0.0002862945,0.0093365,0.00022878527],"about_ca_topic_score_codex":0.0003375422,"about_ca_topic_score_gemma":0.016550073,"teacher_disagreement_score":0.07158593,"about_ca_system_score_codex":0.00005965037,"about_ca_system_score_gemma":0.00018008197,"threshold_uncertainty_score":0.9235329},"labels":[],"label_agreement":null},{"id":"W4388014730","doi":"10.1152/ajpcell.00346.2023","title":"Versatile lactate signaling via HCAR1: a multifaceted GPCR involved in many biological processes","year":2023,"lang":"en","type":"review","venue":"American Journal of Physiology-Cell Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Government of Canada","keywords":"G protein-coupled receptor; Computational biology; Neuroscience; Biology; Signal transduction; Chemistry; Cell biology","score_opus":0.03497581524866408,"score_gpt":0.2954426848890218,"score_spread":0.2604668696403577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388014730","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.29850549,0.69963634,0.00022885294,0.000020894102,0.00075305696,0.00071398506,0.00007341787,0.000044191118,0.000023772418],"genre_scores_gemma":[0.12134007,0.8760479,0.0009136743,0.0001442983,0.00089316216,0.00007794897,0.00038276348,0.00014680647,0.000053353484],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.994911,0.001195559,0.0017356392,0.0010299734,0.00021341507,0.0009143803],"domain_scores_gemma":[0.9958026,0.00042233386,0.0026805643,0.00052489847,0.00034175633,0.00022785984],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006165303,0.00088410074,0.0035599403,0.00047403845,0.00010447822,0.00002169289,0.0010876545,0.00070368836,0.000105414816],"category_scores_gemma":[0.00028677247,0.0006720434,0.0009773496,0.00091585366,0.00062221766,0.00001527544,0.0003729441,0.0010753758,0.000076775235],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033899045,0.00024541427,0.0000048787015,0.0022683567,0.0004805356,0.000025291043,0.00010922867,0.00041163145,0.9596635,0.0000033763629,0.0002307448,0.03621805],"study_design_scores_gemma":[0.008474083,0.02976874,0.00029789002,0.01615552,0.002278753,0.00042333335,0.00480366,0.00037680953,0.19945464,0.002957261,0.72728163,0.0077276803],"about_ca_topic_score_codex":0.000055805507,"about_ca_topic_score_gemma":0.000010205393,"teacher_disagreement_score":0.76020885,"about_ca_system_score_codex":0.000090179325,"about_ca_system_score_gemma":0.000686111,"threshold_uncertainty_score":0.99957305},"labels":[],"label_agreement":null},{"id":"W4388204296","doi":"10.1101/2023.10.25.564052","title":"Noradrenergic alpha-2a Receptor Stimulation Enhances Prediction Error Signaling in Anterior Cingulate Cortex and Striatum","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Striatum; Neuroscience; Anterior cingulate cortex; Psychology; Dorsolateral prefrontal cortex; Prefrontal cortex; Stimulation; Ventral striatum; Cognition; Dopamine","score_opus":0.01405488642067665,"score_gpt":0.2324578848275038,"score_spread":0.21840299840682714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388204296","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99236774,0.001600598,0.0029883948,0.000044299457,0.0019772984,0.0006323579,0.00023240822,0.0001551884,0.000001704987],"genre_scores_gemma":[0.9950267,0.001041282,0.0027365463,0.000045303008,0.0008526554,0.000113881295,0.000012603578,0.00014713271,0.000023861072],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99693596,0.00016984278,0.0007790574,0.0012869309,0.00031040935,0.0005177804],"domain_scores_gemma":[0.9984411,0.000028364137,0.00048725822,0.0006161776,0.0002378047,0.00018928334],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007376149,0.0005451252,0.00056804746,0.0003038505,0.00015191521,0.00018873008,0.00029476648,0.00077994086,0.00003395421],"category_scores_gemma":[0.00016607682,0.00060780096,0.0001476247,0.00030866184,0.00007352024,0.000022733406,0.00037594623,0.00045958033,0.000012869534],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009415373,0.000047600155,0.0067456,0.00018226905,0.00009649693,0.000010887846,0.000013373489,0.0019617637,0.99075407,0.000034105688,0.00005264233,0.0000070657084],"study_design_scores_gemma":[0.00078614085,0.0001868751,0.043291483,0.0007469954,0.0000676383,3.090639e-8,0.000011425412,0.0043036416,0.9494712,0.000005772461,0.00046521466,0.00066360406],"about_ca_topic_score_codex":0.00008991975,"about_ca_topic_score_gemma":0.00001830936,"teacher_disagreement_score":0.041282862,"about_ca_system_score_codex":0.00008172986,"about_ca_system_score_gemma":0.00027200932,"threshold_uncertainty_score":0.9996373},"labels":[],"label_agreement":null},{"id":"W4388222199","doi":"10.26434/chemrxiv-2023-mbr7t-v2","title":"A mechanistic model explaining ligand affinity for, and partial agonism of, cannabinoid receptor 1","year":2023,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; Alliance de recherche numérique du Canada; University of Windsor","keywords":"Cannabinoid; Cannabinoid receptor; Agonism; Chemistry; In silico; Ligand (biochemistry); Intrinsic activity; Receptor; Mechanism (biology); Molecular model; Mechanism of action; Stereochemistry; Computational biology; Biology; Biochemistry; Agonist; In vitro","score_opus":0.0406030985758955,"score_gpt":0.27541399964811236,"score_spread":0.23481090107221686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388222199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87743545,0.0005723196,0.12043311,0.000102724574,0.00072231155,0.0004941169,0.0001135051,0.000041388776,0.0000851068],"genre_scores_gemma":[0.98552585,0.0004980105,0.011800908,0.000052175787,0.00045405613,0.0002809861,0.0005283494,0.00008800136,0.00077164266],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984348,0.000027544058,0.00037639905,0.0006954645,0.00013930148,0.00032649375],"domain_scores_gemma":[0.999036,0.000025525484,0.0002490501,0.0004182817,0.0001419264,0.00012918106],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004082184,0.00031355774,0.00041329843,0.000057786918,0.000105721156,0.000044022778,0.00025099504,0.0005598362,0.000012389935],"category_scores_gemma":[0.0002283015,0.0003289802,0.00019795565,0.000042825668,0.00006870522,0.000002463112,0.00055641215,0.00021793907,0.0000023375308],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009290654,0.000026938602,0.0000139154845,0.00032970216,0.00009341474,8.5964257e-7,0.00020079457,0.0013000444,0.99524957,0.001214377,0.0011912733,0.00028621696],"study_design_scores_gemma":[0.00040816545,0.0001392565,0.0000032515047,0.00011066111,0.00006862472,0.0000015038829,0.00007621536,0.012978097,0.9776502,0.0074353307,0.000772063,0.00035661532],"about_ca_topic_score_codex":0.000027953367,"about_ca_topic_score_gemma":0.000008673626,"teacher_disagreement_score":0.1086322,"about_ca_system_score_codex":0.000016398815,"about_ca_system_score_gemma":0.00021812497,"threshold_uncertainty_score":0.9999162},"labels":[],"label_agreement":null},{"id":"W4388271892","doi":"10.1016/j.jcjd.2023.10.240","title":"ELECLAZINE: THE HIDDEN ANTIDIABETIC POTENTIAL?","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Traditional medicine","score_opus":0.0069983108911202616,"score_gpt":0.20250351213750026,"score_spread":0.19550520124638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388271892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966016,0.0016809914,0.000045447043,0.00089370884,0.0005504797,0.00004879319,0.000009418526,0.0000033587341,0.00016623242],"genre_scores_gemma":[0.99856824,0.000050235765,0.00007811514,0.00033212695,0.0005102618,0.0000017680838,0.000013730437,0.000017958255,0.0004275371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923116,0.000050197646,0.00019133929,0.0000944787,0.0001023863,0.00033045808],"domain_scores_gemma":[0.9993738,0.000013094392,0.00009770691,0.00015018843,0.000118906086,0.00024631576],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038907124,0.000087903914,0.00011564123,0.0001099928,0.00014375203,0.000056752484,0.00029112538,0.00007278923,0.00013102153],"category_scores_gemma":[0.00011629608,0.00006249718,0.00012271947,0.00017587647,0.000057032226,0.0000043423743,0.000016692713,0.00010931547,0.00003128166],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000016730967,0.000004408564,0.014207105,0.00001109782,0.0001227649,0.000017413673,0.00007107602,0.00020486853,0.94160163,0.00010982394,0.03731616,0.006331969],"study_design_scores_gemma":[0.0007669941,0.0006696257,0.040289126,0.000092219765,0.00010871237,0.00002548775,0.00053337927,0.00031841584,0.8175866,0.0024023578,0.1367587,0.0004483902],"about_ca_topic_score_codex":0.000039551865,"about_ca_topic_score_gemma":0.00028531346,"teacher_disagreement_score":0.124015056,"about_ca_system_score_codex":0.000011816343,"about_ca_system_score_gemma":0.00036830152,"threshold_uncertainty_score":0.2548561},"labels":[],"label_agreement":null},{"id":"W4388681746","doi":"10.20944/preprints202311.0832.v1","title":"Control of CCR5 Cell Surface Targeting by the PRAF2 Gatekeeper","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Montréal","keywords":"COPII; Cell biology; Endoplasmic reticulum; G protein-coupled receptor; Vesicle; Receptor; Chemokine receptor; Transmembrane domain; Chemistry; Intracellular; Biology; Biochemistry; Golgi apparatus; Signal transduction; Chemokine; Secretory pathway; Membrane","score_opus":0.04941626866493517,"score_gpt":0.2973451477605731,"score_spread":0.2479288790956379,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388681746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99073905,0.0012236413,0.005340828,0.00028491637,0.00070287625,0.0006347305,0.000121499324,0.000047467925,0.00090500375],"genre_scores_gemma":[0.99467105,0.00039761286,0.00030203516,0.00012407951,0.0002377906,0.0000652735,0.0002481077,0.00008247232,0.0038715852],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976269,0.00025289503,0.0005599669,0.0008768489,0.00029787445,0.00038549982],"domain_scores_gemma":[0.99813473,0.00006109109,0.00046463506,0.0010551219,0.0001931653,0.000091255475],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0013036227,0.0003443996,0.00040358567,0.000026630756,0.00010849639,0.00002091372,0.0008160711,0.00050365436,0.00038303874],"category_scores_gemma":[0.00022492255,0.00028325545,0.00032006536,0.000067533314,0.000092463124,0.0000027385297,0.0013294321,0.0005390459,0.00019874795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050894727,0.00005978053,0.017552847,0.00011488621,0.00014739312,0.0000015120283,0.00013809632,0.0060904888,0.97449976,0.000022548867,0.0012877284,0.000034066074],"study_design_scores_gemma":[0.00040673162,0.000034637556,0.0007553805,0.000049536804,0.0000584424,0.0000012103433,0.00014494997,0.00034494555,0.98696893,0.00022938786,0.010699056,0.00030677655],"about_ca_topic_score_codex":0.00023075168,"about_ca_topic_score_gemma":0.0000054028483,"teacher_disagreement_score":0.016797468,"about_ca_system_score_codex":0.000021423046,"about_ca_system_score_gemma":0.00013031428,"threshold_uncertainty_score":0.999962},"labels":[],"label_agreement":null},{"id":"W4388724871","doi":"10.22541/au.170011992.20997426/v1","title":"Inhibition of HCN1 currents by norquetiapine, an active metabolite of the atypical anti-psychotic drug quetiapine","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Quetiapine; Quetiapine Fumarate; Pharmacology; Schizophrenia (object-oriented programming); Chemistry; Metabolite; Phencyclidine; Antipsychotic; Atypical antipsychotic; Neuroscience; Medicine; Psychology; Biochemistry; Psychiatry; NMDA receptor; Receptor","score_opus":0.01731339841145227,"score_gpt":0.2791127146669747,"score_spread":0.26179931625552244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388724871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924273,0.0007347762,0.004772912,0.00013572152,0.0008869859,0.00046547552,0.00040010913,0.000019080158,0.00015762725],"genre_scores_gemma":[0.99646014,0.0008083493,0.0005896178,0.00005897936,0.00019412382,0.000029431827,0.001169065,0.000047254103,0.0006430471],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99814045,0.0002047465,0.0005250727,0.0005999022,0.000302421,0.00022739245],"domain_scores_gemma":[0.99853706,0.000011688479,0.00041583084,0.00071869686,0.0002340793,0.00008265175],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027134691,0.00029426708,0.0004495838,0.0000644261,0.000045532823,0.000016911978,0.00040053265,0.0003692294,0.00010521382],"category_scores_gemma":[0.000054488028,0.00021822,0.00033238076,0.00012897332,0.0001150028,0.000004822269,0.00053821,0.00032317717,0.0000038795733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010378469,0.00019266903,0.00030673668,0.00014223093,0.00014293769,2.533114e-7,0.00010050043,0.00021810649,0.995977,0.00024323998,0.0017122703,0.0008603105],"study_design_scores_gemma":[0.00038303476,0.00008020804,0.0016251478,0.00014166972,0.00007628762,9.623856e-7,0.000101745674,0.00018408996,0.9953387,0.0011666538,0.00067015254,0.00023136608],"about_ca_topic_score_codex":0.0001437312,"about_ca_topic_score_gemma":0.000031817657,"teacher_disagreement_score":0.0041832943,"about_ca_system_score_codex":0.000011395481,"about_ca_system_score_gemma":0.00010129427,"threshold_uncertainty_score":0.8898753},"labels":[],"label_agreement":null},{"id":"W4388797600","doi":"10.1007/978-3-031-39928-2_25","title":"Prevention of β-Adrenoceptor-Mediated Alterations in Female Heart Failure by Estrogen","year":2023,"lang":"en","type":"book-chapter","venue":"Advances in biochemistry in health and disease","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Adenylyl cyclase; Internal medicine; Endocrinology; Heart failure; Medicine; Adrenergic; Receptor","score_opus":0.009513745029469731,"score_gpt":0.28144505340936343,"score_spread":0.2719313083798937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388797600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6683102,0.31854123,0.00036179178,0.0018675498,0.00058690034,0.0027320345,0.0030749035,0.0000673841,0.004457953],"genre_scores_gemma":[0.8993274,0.042963374,0.0018186878,0.0010258644,0.00044259164,0.0003412287,0.01636847,0.00018091116,0.03753146],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985059,0.000029712934,0.0005717969,0.00049164984,0.00013665942,0.0002642847],"domain_scores_gemma":[0.9991973,0.00002746923,0.00020459198,0.00022571786,0.000031640702,0.00031325413],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017322942,0.00022896592,0.00031442585,0.000087437504,0.00003122211,0.000009391158,0.00010305147,0.00024073402,0.000061879604],"category_scores_gemma":[0.00014600622,0.00025862516,0.000071931296,0.00006596473,0.000068887486,0.000009391014,0.000057102676,0.00018173916,0.0000021839553],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004958302,0.0020166521,0.08775836,0.029187279,0.00021575257,0.00014278322,0.0008027877,0.0030185445,0.8078344,0.009504309,0.02268117,0.03187967],"study_design_scores_gemma":[0.013168141,0.0034807527,0.00061726524,0.016296847,0.00009787769,0.000025852925,0.0021535982,0.00076396903,0.41700563,0.051250905,0.48983017,0.0053090015],"about_ca_topic_score_codex":0.000026090749,"about_ca_topic_score_gemma":0.000079757214,"teacher_disagreement_score":0.467149,"about_ca_system_score_codex":0.00004556626,"about_ca_system_score_gemma":0.0004927047,"threshold_uncertainty_score":0.9999866},"labels":[],"label_agreement":null},{"id":"W4389007709","doi":"10.1096/fasebj.30.1_supplement.1016.4","title":"Altered metabolism in RGS2 KO mice","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Western University","funders":"","keywords":"RGS2; Internal medicine; Endocrinology; Metabolism; Regulator of G protein signaling; Biology; Wild type; Chemistry; G protein; Medicine; Biochemistry; Receptor; Gene; GTPase-activating protein","score_opus":0.011418683101984283,"score_gpt":0.23181699012718676,"score_spread":0.22039830702520247,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389007709","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916949,0.0010741727,0.0057937577,0.00058214593,0.0004423766,0.00004748048,0.0000046097052,0.0000028635986,0.0003576868],"genre_scores_gemma":[0.9973928,0.00038279413,0.00034303876,0.00024428437,0.0008171879,0.0000025187421,0.0000016183094,0.000011700062,0.00080406084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993156,0.000101874175,0.00016594508,0.00011246766,0.000102123086,0.00020199314],"domain_scores_gemma":[0.99966806,0.00001345649,0.0000743103,0.0001461564,0.000035694244,0.00006230676],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004590318,0.00008426458,0.00008995915,0.000030309335,0.00008068952,0.000027912052,0.00022712891,0.000057366928,0.00027936403],"category_scores_gemma":[0.000043986194,0.00004168358,0.000078538425,0.0000398566,0.000029168681,0.000004252606,0.0000466513,0.00010297171,0.000023714461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043709053,0.00001090637,0.00015505585,7.065371e-7,0.000018991384,0.0000038268386,0.000040338928,0.00000985736,0.9934278,0.00014970874,0.00064304145,0.0054960256],"study_design_scores_gemma":[0.0006027674,0.00004798999,0.00048752362,0.000018791245,0.000008820425,0.00012189881,0.000056551893,0.000007901509,0.9852437,0.0008916102,0.012428584,0.000083889776],"about_ca_topic_score_codex":0.0000067573214,"about_ca_topic_score_gemma":0.000014512151,"teacher_disagreement_score":0.011785542,"about_ca_system_score_codex":0.000009599197,"about_ca_system_score_gemma":0.0000398784,"threshold_uncertainty_score":0.30588403},"labels":[],"label_agreement":null},{"id":"W4389008254","doi":"10.1096/fasebj.30.1_supplement.945.12","title":"Angiotensin II Inhibits T‐type Ca <sup>2+</sup> Channels in Cerebral Arterial Smooth Muscle Cells","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Calgary; Western University","funders":"","keywords":"Angiotensin II; NADPH oxidase; Losartan; Chemistry; Patch clamp; Protein kinase C; Vascular smooth muscle; Endocrinology; Internal medicine; Myocyte; Cerebral arteries; Gq alpha subunit; Reactive oxygen species; Biophysics; Receptor; Signal transduction; Biology; Biochemistry; G protein; Medicine; Smooth muscle","score_opus":0.011092013610939004,"score_gpt":0.21434946915807418,"score_spread":0.20325745554713517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389008254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99709237,0.00017650166,0.0009745736,0.00070679706,0.0008127629,0.0001086932,0.000015211147,0.000006593587,0.000106519],"genre_scores_gemma":[0.9967753,0.00011768869,0.0002654002,0.00035111303,0.0017984555,0.000002244404,0.000008404339,0.000027189591,0.0006541898],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987795,0.00014102408,0.00027735144,0.00022574625,0.00017438605,0.00040203633],"domain_scores_gemma":[0.9994368,0.000014673967,0.00010577117,0.00023331011,0.00008431795,0.00012515346],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048587986,0.00017532446,0.00016726281,0.00006103662,0.0002273637,0.00005911334,0.00025144735,0.00014978889,0.00055513077],"category_scores_gemma":[0.000042636013,0.00010129147,0.00012432988,0.00009066259,0.000057825277,0.000011415531,0.00012420658,0.00016836113,0.000042376545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012228751,0.00003392925,0.000019383375,0.0000014404228,0.000019605324,0.000013184803,0.00029988593,0.00078466086,0.99299824,0.00001755764,0.0029080731,0.0027817688],"study_design_scores_gemma":[0.0011538325,0.000382728,0.000046800316,0.00005618787,0.000012080624,0.00006079303,0.00015999886,0.00037113635,0.987212,0.00031466412,0.010039046,0.00019073201],"about_ca_topic_score_codex":0.000018219589,"about_ca_topic_score_gemma":0.0000058204273,"teacher_disagreement_score":0.007130973,"about_ca_system_score_codex":0.000028798593,"about_ca_system_score_gemma":0.000091336726,"threshold_uncertainty_score":0.6078293},"labels":[],"label_agreement":null},{"id":"W4389019395","doi":"10.1096/fasebj.31.1_supplement.868.1","title":"Tumor Necrosis Factor Alpha Increases Excitability in Subfornical Organ Neurons","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Depolarization; Subfornical organ; Rheobase; Endocrinology; Tumor necrosis factor alpha; Internal medicine; Medicine; Chemistry; Angiotensin II; Receptor","score_opus":0.020837252028377353,"score_gpt":0.26663424606901925,"score_spread":0.2457969940406419,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389019395","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987158,0.00011572609,0.0003613947,0.0002985151,0.00023178564,0.00008628843,0.000020358846,0.000004465326,0.00016565336],"genre_scores_gemma":[0.99906415,0.00007144972,0.00014694028,0.00019569066,0.00037058827,0.0000036202744,0.0000051722686,0.000016415604,0.00012596583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902445,0.00013139221,0.00023407156,0.00019212245,0.00014475659,0.00027319844],"domain_scores_gemma":[0.9991108,0.000026836018,0.00017347712,0.0005006901,0.000053132888,0.00013501973],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004889095,0.00013057548,0.00014710521,0.000022110244,0.00060599385,0.00020096877,0.0005782729,0.000067068984,0.00035526318],"category_scores_gemma":[0.000499218,0.000086919885,0.0001276054,0.000023793938,0.00013139984,0.000010996967,0.00017471256,0.00027863725,0.00001085984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007773566,0.00006172729,0.023338867,0.0000027823842,0.000015545837,0.000017485416,0.000046993897,0.000007938344,0.97492385,0.000025526922,0.00009862452,0.0013829118],"study_design_scores_gemma":[0.000730997,0.00023048247,0.11197395,0.00002114464,0.000015650274,0.00021622614,0.00009181522,0.000083181585,0.8843503,0.0005619452,0.001541441,0.00018284304],"about_ca_topic_score_codex":0.0001498189,"about_ca_topic_score_gemma":0.00012154798,"teacher_disagreement_score":0.090573534,"about_ca_system_score_codex":0.000026993303,"about_ca_system_score_gemma":0.00015521677,"threshold_uncertainty_score":0.4660876},"labels":[],"label_agreement":null},{"id":"W4389020177","doi":"10.1096/fasebj.31.1_supplement.847.6","title":"Presynaptic organization of CaV2 channels with specific vesicle pools in SCG vs rat tail artery","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene isoform; Vesicle; Norepinephrine; Synaptic vesicle; Sympathetic nervous system; Superior cervical ganglion; Biology; Cell biology; Internal medicine; Chemistry; Anatomy; Endocrinology; Medicine; Dopamine; Biochemistry; Blood pressure; Gene","score_opus":0.011869032159543838,"score_gpt":0.21736532139788686,"score_spread":0.205496289238343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389020177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950429,0.00015942295,0.0041798744,0.00019291646,0.00022179073,0.00008850745,0.0000020679986,0.0000020713326,0.00011043169],"genre_scores_gemma":[0.99902135,0.0001640662,0.00022606038,0.00004035051,0.00030889138,0.0000014370438,0.0000061501755,0.000016249483,0.00021544089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993876,0.000056151206,0.00016788924,0.00011413557,0.00011998375,0.00015419384],"domain_scores_gemma":[0.99934685,0.0000065827558,0.00020911,0.00029347854,0.00009736874,0.000046625824],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003036765,0.00008668407,0.00011326323,0.000028432563,0.00023064725,0.000108982524,0.00029737805,0.000056366964,0.000111185895],"category_scores_gemma":[0.000043095482,0.00005613576,0.000031849377,0.000041085095,0.000063639956,0.000011953383,0.00005195357,0.00011730306,0.0000049648597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006950748,0.000023544686,0.0030666958,0.0000040306,0.000023682735,0.000011411585,0.00012545112,0.0004576548,0.9954555,0.000053514403,0.0001759497,0.0005330768],"study_design_scores_gemma":[0.0005658793,0.00022756723,0.0023276329,0.00004559627,0.000010284335,0.00013078791,0.0001535912,0.00007976829,0.99604577,0.00011964823,0.00021059842,0.00008288803],"about_ca_topic_score_codex":0.000005563127,"about_ca_topic_score_gemma":0.0000053678023,"teacher_disagreement_score":0.003978437,"about_ca_system_score_codex":0.000010517037,"about_ca_system_score_gemma":0.000051793915,"threshold_uncertainty_score":0.22891499},"labels":[],"label_agreement":null},{"id":"W4389034046","doi":"10.1096/fasebj.30.1_supplement.976.5","title":"Function of the Ang II system during the ontogeny of Archosaurs","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Internal medicine; Endocrinology; Biology; Baroreflex; Ontogeny; Angiotensin II; Alligator; Extant taxon; Receptor; Blood pressure; Embryogenesis; Agonist; Renin–angiotensin system; Cell biology; Medicine; Embryo; Heart rate; Evolutionary biology","score_opus":0.006817802309228208,"score_gpt":0.19333625750455266,"score_spread":0.18651845519532445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389034046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99664676,0.0004239721,0.0020512147,0.00018480199,0.00045427133,0.000072234114,0.0000065833738,0.000001890643,0.0001582536],"genre_scores_gemma":[0.99902004,0.00006096316,0.000024139958,0.000023688066,0.00036002218,0.0000018992222,3.3460378e-7,0.000007596109,0.0005013007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934065,0.00012288516,0.0001935303,0.000068657806,0.00015637594,0.0001178929],"domain_scores_gemma":[0.99940395,0.000014793949,0.00021940915,0.00024611971,0.00009130227,0.000024416297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049651496,0.000064165506,0.00007670833,0.000012456215,0.00027642475,0.000007776381,0.00028469026,0.00004088816,0.000041694686],"category_scores_gemma":[0.000038014263,0.000022181006,0.00013942191,0.000040680396,0.000067552326,0.0000028032475,0.00009091806,0.00008058641,8.841741e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000688725,0.0000071449736,0.00061951077,0.000009105783,0.000053119566,1.8497867e-7,0.00008317501,0.000048837584,0.9977856,0.00020985233,0.0000737268,0.0010408277],"study_design_scores_gemma":[0.0002637826,0.00010755299,0.003220816,0.00008822468,0.000026720672,0.00006055161,0.00039412075,0.000007668256,0.9951953,0.000080736696,0.0005180758,0.000036449055],"about_ca_topic_score_codex":0.000007678666,"about_ca_topic_score_gemma":0.000005173132,"teacher_disagreement_score":0.002601305,"about_ca_system_score_codex":0.000014649351,"about_ca_system_score_gemma":0.00003631835,"threshold_uncertainty_score":0.21260637},"labels":[],"label_agreement":null},{"id":"W4389204687","doi":"10.1038/s41467-023-42848-5","title":"How carvedilol does not activate β2-adrenoceptors","year":2023,"lang":"en","type":"letter","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Carvedilol; Adrenergic receptor; Pharmacology; Chemistry; Medicine; Computer science; Receptor; Internal medicine; Heart failure","score_opus":0.02201889401187406,"score_gpt":0.2753916602928139,"score_spread":0.25337276628093985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389204687","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021630428,0.0039905477,0.0002484372,0.98780966,0.0028843142,0.0005816175,0.00096131297,0.00018575623,0.0011752868],"genre_scores_gemma":[0.26346365,0.009372366,0.00751571,0.58083063,0.015033986,0.0005391172,0.036514696,0.0005871315,0.08614269],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983499,0.00021950662,0.0002343084,0.00052259257,0.00029302924,0.000380682],"domain_scores_gemma":[0.9964116,0.00011507376,0.00023488369,0.0029315965,0.00024310863,0.000063719664],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["research_integrity"],"category_scores_codex":[0.0001956305,0.00036926076,0.0003070313,0.00012890156,0.0003460835,0.0001748761,0.0020650858,0.0028571791,0.000052008098],"category_scores_gemma":[0.00022896139,0.0002981213,0.00026305008,0.0001773498,0.00013292774,0.0000069464218,0.0008205185,0.0036520357,0.00003990215],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000051537418,0.000012735324,0.000013804673,0.000023680203,0.00013558615,0.0000039130587,0.00002344671,9.1418053e-7,0.22192998,0.000108096945,0.77716726,0.0005754098],"study_design_scores_gemma":[0.000106296146,0.0000349509,0.000011393203,0.000030215699,0.00004701091,0.0000039040597,0.00004825799,0.000008721232,0.15882926,0.00008467276,0.8404604,0.00033487665],"about_ca_topic_score_codex":0.000025907715,"about_ca_topic_score_gemma":0.00015009897,"teacher_disagreement_score":0.40697902,"about_ca_system_score_codex":0.000040221566,"about_ca_system_score_gemma":0.00011738598,"threshold_uncertainty_score":0.9999471},"labels":[],"label_agreement":null},{"id":"W4389446646","doi":"10.1212/wnl.94.15_supplement.4593","title":"In-vitro Profile of a Novel Long Lasting Dopamine Agonist Designed to Optimize Efficacy and Safety (4593)","year":2020,"lang":"en","type":"article","venue":"Neurology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Xenon Pharmaceuticals (Canada)","funders":"","keywords":"Agonist; Safety profile; Medicine; Dopamine; Dopamine agonist; In vitro; Internal medicine; Adverse effect; Biology; Receptor; Genetics","score_opus":0.014829394616703273,"score_gpt":0.23803727498843025,"score_spread":0.22320788037172698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389446646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96911746,0.00009072732,0.028757624,0.0014758126,0.000096170705,0.00025319227,0.000013423936,0.00000819627,0.00018736937],"genre_scores_gemma":[0.987694,0.000017173186,0.01004633,0.002015527,0.0001455237,0.000011938851,0.000022039007,0.000020001247,0.000027415434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99907804,0.000054685308,0.00023345616,0.00036153,0.000060710256,0.00021157098],"domain_scores_gemma":[0.99963486,0.00004139312,0.00006858547,0.00011979944,0.000033377873,0.000101981794],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000108811015,0.00012109479,0.00021362487,0.000028461425,0.000055594846,0.000013859045,0.00011700934,0.00011629923,0.000030545052],"category_scores_gemma":[0.00017970649,0.00012053588,0.000033317272,0.00009865798,0.000039403953,0.0000026850416,0.00014422067,0.00010295328,0.0000023866864],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021547063,0.000046176327,0.00011796531,0.000017633283,0.000010095906,0.000012456591,0.000051035368,0.0011147722,0.99563885,0.000020089145,0.00006007454,0.0007561681],"study_design_scores_gemma":[0.0019781599,0.001852363,0.00068399234,0.0000048125853,0.000009689389,0.000026993768,0.000007163387,0.0018791272,0.9912918,0.0000022490344,0.0021267512,0.00013690426],"about_ca_topic_score_codex":0.000018506182,"about_ca_topic_score_gemma":0.000006676828,"teacher_disagreement_score":0.018711293,"about_ca_system_score_codex":0.0000022219106,"about_ca_system_score_gemma":0.000027821889,"threshold_uncertainty_score":0.49153104},"labels":[],"label_agreement":null},{"id":"W4389685627","doi":"10.3390/ijms242417438","title":"Control of CCR5 Cell-Surface Targeting by the PRAF2 Gatekeeper","year":2023,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Montréal; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale","keywords":"Cell biology; Endoplasmic reticulum; ER retention; Receptor; Transmembrane domain; G protein-coupled receptor; Chemokine receptor; Transport protein; Biology; Cell membrane; Chemistry; Mutant; Cell; Biochemistry; Signal transduction; Chemokine","score_opus":0.007357511949732655,"score_gpt":0.2580147213893394,"score_spread":0.25065720943960673,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389685627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9671976,0.001463921,0.029521283,0.0009491468,0.00052358827,0.000044204542,0.000008636403,0.000002585215,0.0002890502],"genre_scores_gemma":[0.99835193,0.00013796422,0.0010430402,0.00025254447,0.00010644097,7.3097283e-7,0.000004216335,0.000005870321,0.00009723208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988583,0.0000742101,0.0002799385,0.000115473376,0.0005472326,0.0001248605],"domain_scores_gemma":[0.99926853,0.000033528493,0.00029965816,0.0000641344,0.0002981726,0.00003597219],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00105818,0.000069191534,0.00009192621,0.00004506643,0.000061312945,0.000046871966,0.0006534598,0.000040015526,0.000034836703],"category_scores_gemma":[0.00011405522,0.00004557494,0.0001191224,0.00011991813,0.00011450102,0.000009536422,0.0000635446,0.00007098894,0.0000034938248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019442417,0.000016847298,0.0002325666,0.000001501555,0.000046000496,0.0000084913045,0.00004887971,0.010422756,0.9869037,0.00012872061,0.0018137343,0.00035732798],"study_design_scores_gemma":[0.000330416,0.0001809407,0.00003053336,0.000013521254,0.000008698231,0.000022637212,0.00030129115,0.00094482326,0.9924752,0.00023462326,0.0053984267,0.000058892314],"about_ca_topic_score_codex":0.000008732173,"about_ca_topic_score_gemma":3.8796267e-7,"teacher_disagreement_score":0.031154376,"about_ca_system_score_codex":0.000006308328,"about_ca_system_score_gemma":0.00008604236,"threshold_uncertainty_score":0.1858492},"labels":[],"label_agreement":null},{"id":"W4389850620","doi":"10.4103/1673-5374.389637","title":"Sexual dimorphism of G protein-coupled receptor signaling in the brain","year":2023,"lang":"en","type":"article","venue":"Neural Regeneration Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Sexual dimorphism; Biology; Signal transduction; Neuroscience; Receptor; Cell biology; Genetics; Zoology","score_opus":0.07406714175343677,"score_gpt":0.35464323061992187,"score_spread":0.2805760888664851,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389850620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964793,0.00015331463,0.00023147419,0.0025179484,0.000070521826,0.0004673543,0.0000054514576,0.000009594611,0.0000650794],"genre_scores_gemma":[0.99727446,0.000024322706,0.0001818613,0.000096841766,0.000319898,0.0001327712,0.00015715389,0.000016343873,0.00179634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815553,0.00050827407,0.00023532961,0.00028051613,0.00051692006,0.00030344675],"domain_scores_gemma":[0.99940217,0.0000806359,0.000044689856,0.00026532754,0.00016831748,0.00003887619],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023936743,0.00008747356,0.00009854957,0.0001460728,0.00014561148,0.00004556993,0.00027154703,0.00010902888,0.000096654345],"category_scores_gemma":[0.0004463248,0.000064421714,0.000042043142,0.0005777902,0.000062887186,0.000006035435,0.00008152395,0.00020917483,0.000021091153],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045134333,0.000020463753,0.00006322101,0.000014359098,0.000004980898,0.0000030493754,0.00016143473,0.0013495643,0.99317217,0.00053728203,0.0028237004,0.0018046309],"study_design_scores_gemma":[0.00025667477,0.00036372285,0.00007996702,0.000010346662,8.761319e-7,0.0000015988215,0.00044132458,0.0071981726,0.988706,0.00014850718,0.0027177397,0.00007507923],"about_ca_topic_score_codex":0.00006958974,"about_ca_topic_score_gemma":0.000054389646,"teacher_disagreement_score":0.005848608,"about_ca_system_score_codex":0.000011950869,"about_ca_system_score_gemma":0.00007597481,"threshold_uncertainty_score":0.26270413},"labels":[],"label_agreement":null},{"id":"W4390046003","doi":"10.1126/science.adh1859","title":"Molecular determinants of ligand efficacy and potency in GPCR signaling","year":2023,"lang":"en","type":"article","venue":"Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of Neurological Disorders and Stroke; Novo Nordisk Fonden; Wellcome Trust","keywords":"Allosteric regulation; G protein-coupled receptor; Heterotrimeric G protein; Signal transduction; Ligand (biochemistry); Receptor; G protein; Functional selectivity; Drug discovery; Chemistry; Cell signaling; Biology; Cell biology; Computational biology; Biochemistry; Pharmacology","score_opus":0.011532676404240402,"score_gpt":0.27540038672207917,"score_spread":0.2638677103178388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390046003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99933374,0.00023811612,0.0002002375,0.000013287598,0.00006390195,0.000064228756,0.0000012234225,0.0000048712486,0.00008036682],"genre_scores_gemma":[0.999491,0.000050280087,0.00038210262,0.00002119481,0.0000133986505,0.0000023327925,0.0000012000052,0.0000049153696,0.00003361286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993006,0.0000120799505,0.0001234243,0.00024067359,0.00013592678,0.00018731828],"domain_scores_gemma":[0.9997504,0.0000071878676,0.00003644808,0.00012504729,0.000034553817,0.000046363137],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004645621,0.000057433044,0.00007903615,0.00009320304,0.000048457514,0.000015403451,0.00015685977,0.00003788789,0.0000031712398],"category_scores_gemma":[0.00011861594,0.000052697447,0.000016620195,0.00037864063,0.00013406084,0.000004700016,0.00010691653,0.000029979377,0.000002182575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005456135,0.0000069018283,0.0022149696,0.0000077521445,6.8657556e-7,0.000005969025,0.000065844644,0.00019492993,0.99312264,0.00003209779,0.000001375913,0.0043413932],"study_design_scores_gemma":[0.0001761625,0.0000926404,0.00496564,0.000022319653,0.0000015228161,0.0000033317974,0.000067205954,0.00066263747,0.9936896,0.00020069175,0.000051058476,0.00006719473],"about_ca_topic_score_codex":0.0000101034875,"about_ca_topic_score_gemma":0.0000037852203,"teacher_disagreement_score":0.004274199,"about_ca_system_score_codex":0.0000032419834,"about_ca_system_score_gemma":0.00005903097,"threshold_uncertainty_score":0.21489395},"labels":[],"label_agreement":null},{"id":"W4390047463","doi":"10.1124/jpet.123.001920","title":"The β-Blocker Carvedilol and Related Aryloxypropanolamines Promote ERK1/2 Phosphorylation in HEK293 Cells with KA Values Distinct From Their Equilibrium Dissociation Constants as β2-Adrenoceptor Antagonists: Evidence for Functional Affinity","year":2023,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Carvedilol; Dissociation constant; Phosphorylation; Chemistry; Dissociation (chemistry); HEK 293 cells; Pharmacology; Cardiology; Biochemistry; Physical chemistry; Medicine; Receptor; Heart failure","score_opus":0.030563942855339254,"score_gpt":0.31408570891388615,"score_spread":0.2835217660585469,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390047463","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99192,0.0066903955,0.000112144204,0.0003323756,0.0006192768,0.0002762451,0.00003624243,0.0000065754994,0.0000067617084],"genre_scores_gemma":[0.9981075,0.0012759822,0.00013141106,0.00011474651,0.00021670786,0.000018057994,0.000032262513,0.000015785678,0.00008753918],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913174,0.00010882011,0.00029265485,0.00017960249,0.000114662864,0.0001725374],"domain_scores_gemma":[0.99938166,0.00017578906,0.00025679587,0.000051022405,0.00009060421,0.00004413835],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041120584,0.0001415477,0.0001686869,0.000033134023,0.00019524239,0.000034316,0.00007943163,0.000112853806,0.000029421215],"category_scores_gemma":[0.000017987426,0.000093347684,0.00004989222,0.00007526406,0.00014775786,0.000025277997,0.00004330373,0.00012872613,6.459801e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002053511,0.0000651592,0.0020838706,0.0000066004827,0.0002150094,0.00000321625,0.0005606823,0.000032945714,0.9939905,0.000009535382,0.00022949878,0.0007494768],"study_design_scores_gemma":[0.0016677661,0.00090783654,0.002077582,0.000031670614,0.000067871995,0.000023852574,0.0010377739,0.0011875499,0.99174225,0.0003829966,0.0007518885,0.00012098233],"about_ca_topic_score_codex":0.0000054694515,"about_ca_topic_score_gemma":0.0000032396592,"teacher_disagreement_score":0.0061875237,"about_ca_system_score_codex":0.000036714446,"about_ca_system_score_gemma":0.0000883368,"threshold_uncertainty_score":0.3806608},"labels":[],"label_agreement":null},{"id":"W4390367061","doi":"10.20944/preprints202312.2143.v1","title":"Development of Novel Bioluminescent Biosensors Monitoring Conformation and Activity of Merlin Tumor Suppressor","year":2023,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research","keywords":"Merlin (protein); Luciferase; Suppressor; Bioluminescence; Carcinogenesis; Biosensor; Cell growth; In vitro; Chemistry; Cell biology; Cell; Cancer; Cancer research; Biology; Biophysics; Biochemistry; Genetics; Transfection; Gene","score_opus":0.13428473723014905,"score_gpt":0.3401682288744475,"score_spread":0.20588349164429842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390367061","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99680215,0.00007515899,0.0021424843,0.000014630581,0.00047450085,0.0003713885,0.00004820076,0.000020244272,0.00005125029],"genre_scores_gemma":[0.99503815,0.00014379567,0.004485869,0.0000029368255,0.00009037581,0.000045348166,0.000075188684,0.000029925171,0.00008838207],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985065,0.0000377831,0.00055017363,0.0004914196,0.00021701277,0.00019714689],"domain_scores_gemma":[0.9987381,0.00001578843,0.0005295579,0.00046689596,0.0001776323,0.000072017356],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00052113476,0.00023996446,0.00036304863,0.00009882216,0.000050203915,0.000006044461,0.00024007027,0.00025030767,0.000022782024],"category_scores_gemma":[0.00012966966,0.00024750296,0.000109924746,0.00005665835,0.00006240866,0.000005378624,0.0011676762,0.00018911125,0.000007087189],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007333405,0.000091631315,0.020190405,0.00044274074,0.00013043154,3.9207941e-7,0.00048229765,0.00028909725,0.97781676,0.000007415009,0.0000019915287,0.00047347537],"study_design_scores_gemma":[0.00032356885,0.000019986663,0.04703711,0.00023238652,0.000024378154,0.0000015798056,0.00018101632,0.00026520868,0.9514512,0.000009162561,0.0002413083,0.00021311406],"about_ca_topic_score_codex":0.00006571373,"about_ca_topic_score_gemma":0.0000054403454,"teacher_disagreement_score":0.026846705,"about_ca_system_score_codex":0.000024367797,"about_ca_system_score_gemma":0.00013921004,"threshold_uncertainty_score":0.99999774},"labels":[],"label_agreement":null},{"id":"W4390618313","doi":"10.7554/elife.89376.2","title":"Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Japan Society for the Promotion of Science; Fujita Health University; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development","keywords":"Endophenotype; Schizophrenia (object-oriented programming); Autism; Neuroscience; Disease; Autism spectrum disorder; Psychology; Cognition; Bipolar disorder; Medicine; Internal medicine; Psychiatry","score_opus":0.020007256330220796,"score_gpt":0.27816206615012457,"score_spread":0.2581548098199038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390618313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9802114,0.00047061927,0.016945954,0.0001306695,0.00033393654,0.0013360386,0.000392814,0.000038360016,0.00014025584],"genre_scores_gemma":[0.9977695,0.00057851244,0.0006921703,0.00019255043,0.000102203645,0.00010557032,0.00017932385,0.00008847052,0.0002917291],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99769574,0.00018937803,0.0004844672,0.0009464404,0.00027818847,0.00040579357],"domain_scores_gemma":[0.9991094,0.00010863044,0.00022245225,0.0003107887,0.0001099297,0.00013878259],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00041596303,0.00042820125,0.0004628286,0.00014081763,0.00010126183,0.000050351297,0.00023270087,0.0002436371,0.0000592576],"category_scores_gemma":[0.00013835206,0.00041679826,0.00020869653,0.00012844431,0.000050329818,0.0000059454587,0.0005280383,0.00030786672,0.0000042352663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0036786841,0.0045000785,0.02648169,0.0015361792,0.002503694,0.00004530657,0.0208956,0.05038774,0.8868367,0.00032443512,0.0010370446,0.0017728114],"study_design_scores_gemma":[0.049163263,0.043706305,0.07883674,0.001912354,0.0042353505,0.000049276186,0.11441711,0.24984366,0.40967104,0.037982732,0.00020552344,0.009976656],"about_ca_topic_score_codex":0.00024025566,"about_ca_topic_score_gemma":0.0005139527,"teacher_disagreement_score":0.4771657,"about_ca_system_score_codex":0.000016365044,"about_ca_system_score_gemma":0.00022390464,"threshold_uncertainty_score":0.9998284},"labels":[],"label_agreement":null},{"id":"W4390920138","doi":"10.1016/j.jbc.2024.105649","title":"A cholesterol switch controls phospholipid scrambling by G protein–coupled receptors","year":2024,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Eye Institute; Canadian Institutes of Health Research; School of Medicine, University of Virginia; Weill Cornell Medical College; Vetenskapsrådet; Human Frontier Science Program; Science for Life Laboratory; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Karolinska Institutet; Université de Strasbourg; University of Michigan","keywords":"Scrambling; Phospholipid; Receptor; Chemistry; Cholesterol; Cell biology; Biochemistry; Biophysics; Biology; Computer science; Membrane","score_opus":0.013028200706900023,"score_gpt":0.2487133285114173,"score_spread":0.23568512780451728,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4390920138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98906285,0.005820098,0.004096583,0.00024753547,0.00036497557,0.00013064948,0.000013033567,0.00002214141,0.00024212892],"genre_scores_gemma":[0.9966826,0.00044528933,0.00067928125,0.00015238038,0.0011202875,0.000013469476,0.00004040215,0.00002527526,0.0008410199],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985153,0.00004446374,0.0005624601,0.00033528937,0.00022959187,0.00031286228],"domain_scores_gemma":[0.99923277,0.000029203035,0.00022515777,0.00017366793,0.00014347551,0.00019570682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006037499,0.00023896166,0.00033648688,0.000023968041,0.00006290064,0.000119251075,0.0003214304,0.0004175032,0.000505236],"category_scores_gemma":[0.00023247674,0.00016522394,0.00032330098,0.00011012933,0.00007228685,0.00000965866,0.00007323134,0.00041748947,0.000009513959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014078655,0.00006266605,0.00014044685,0.000044993034,0.00011027149,0.000009760595,0.0000122877655,0.00001134527,0.9956711,0.0000068579266,0.002029261,0.0017602255],"study_design_scores_gemma":[0.0005351291,0.00040080614,0.00001389795,0.00013953635,0.000020601658,0.00012388604,0.000062153544,0.00012615185,0.9428094,0.00009785126,0.055463962,0.0002066369],"about_ca_topic_score_codex":0.000002474954,"about_ca_topic_score_gemma":1.0818512e-7,"teacher_disagreement_score":0.0534347,"about_ca_system_score_codex":0.000035213478,"about_ca_system_score_gemma":0.0000927744,"threshold_uncertainty_score":0.6737637},"labels":[],"label_agreement":null},{"id":"W4391150774","doi":"10.1101/2024.01.20.576427","title":"Understanding and predicting ligand efficacy in the mu-opioid receptor through quantitative dynamical analysis of complex structures","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Ligand (biochemistry); Quantitative structure–activity relationship; Opioid receptor; Computational biology; Chemistry; Lasso (programming language); Receptor; Similarity (geometry); Molecular dynamics; Virtual screening; Drug discovery; Opioid; Bioinformatics; Computer science; Biophysics; Stereochemistry; Biology; Computational chemistry; Artificial intelligence; Biochemistry","score_opus":0.04731973297944214,"score_gpt":0.2773996043111423,"score_spread":0.23007987133170016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391150774","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9892585,0.0020703077,0.007451376,0.00008462046,0.00033772155,0.00042837398,0.00032574628,0.00003130733,0.000012025539],"genre_scores_gemma":[0.9941626,0.00044511392,0.005079978,0.000069412716,0.00015214429,0.000026447278,0.0000073679544,0.000055897413,9.965464e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977912,0.00020994013,0.0005381768,0.0008342369,0.00029943392,0.00032704603],"domain_scores_gemma":[0.9988218,0.000117020085,0.000297435,0.00057399645,0.00011995725,0.00006977346],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005992912,0.00038942063,0.0005866459,0.00026331787,0.00011360565,0.00015762988,0.00038097004,0.00045018308,0.000020884781],"category_scores_gemma":[0.00019557119,0.00032145667,0.00022897146,0.00067273504,0.00018165068,0.0000072240737,0.00048729888,0.0005605825,0.0000010222071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047569574,0.00005466584,0.0026430304,0.00024152095,0.0010551583,0.0000064736632,0.00020180072,0.0008180744,0.985894,0.008977732,0.00005916353,7.757956e-7],"study_design_scores_gemma":[0.0011079449,0.00039066531,0.05654893,0.00078275136,0.0024054418,7.77457e-8,0.0008326123,0.016964115,0.91861546,0.00031708172,0.0006530509,0.0013818644],"about_ca_topic_score_codex":0.00006623991,"about_ca_topic_score_gemma":0.000027003925,"teacher_disagreement_score":0.06727857,"about_ca_system_score_codex":0.00007225677,"about_ca_system_score_gemma":0.00016264532,"threshold_uncertainty_score":0.99992377},"labels":[],"label_agreement":null},{"id":"W4391518736","doi":"10.1101/2024.02.02.578166","title":"<i>Npbwr1</i> signaling mediates fast antidepressant action","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Universitätsklinikum Jena","keywords":"Nucleus accumbens; Antidepressant; Depression (economics); Chronic stress; Biomarker; Major depressive disorder; Medicine; Mood; Antagonist; Psychology; Internal medicine; Receptor; Psychiatry; Hippocampus; Biology","score_opus":0.01316793449578483,"score_gpt":0.23093727567278566,"score_spread":0.21776934117700084,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391518736","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9809963,0.009335181,0.004789944,0.00010245933,0.0036927108,0.0005204338,0.00025744602,0.0002808148,0.000024692583],"genre_scores_gemma":[0.99216336,0.0017690263,0.0030663197,0.00018267179,0.002420697,0.0001277355,0.0000046496775,0.00023778818,0.000027731496],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9967813,0.00013191381,0.0005835607,0.0014522552,0.00041856407,0.0006323999],"domain_scores_gemma":[0.9979935,0.000023321021,0.00032243363,0.0010628817,0.00032291465,0.00027494816],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005595021,0.00069157727,0.0005240551,0.00019910472,0.00017092835,0.00035959558,0.0005623831,0.0009445942,0.00010413691],"category_scores_gemma":[0.00011286679,0.0007109494,0.00034414668,0.00024342762,0.00008621902,0.000010085706,0.0010508938,0.00088176155,0.00010702998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003244222,0.000055375865,0.0003880305,0.00041182694,0.00025746436,0.000029993555,0.0000048632214,0.00039061593,0.99735224,0.00019798415,0.00086949207,0.0000096963995],"study_design_scores_gemma":[0.0002365149,0.00007640028,0.00035666424,0.00040425704,0.00015553972,4.1509917e-8,0.000006267726,0.00038931306,0.98625594,0.00001565427,0.011287284,0.0008161489],"about_ca_topic_score_codex":0.000039952207,"about_ca_topic_score_gemma":0.000003535631,"teacher_disagreement_score":0.0111670615,"about_ca_system_score_codex":0.000066220964,"about_ca_system_score_gemma":0.00045898746,"threshold_uncertainty_score":0.9995342},"labels":[],"label_agreement":null},{"id":"W4391609953","doi":"10.1007/s00239-024-10154-3","title":"Scaling up Functional Analyses of the G Protein-Coupled Receptor Rhodopsin","year":2024,"lang":"en","type":"article","venue":"Journal of Molecular Evolution","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; York University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Rhodopsin; Biology; G protein-coupled receptor; Transmembrane domain; Signal transduction; Mutagenesis; Transmembrane protein; Cell biology; Mutant; Genetics; Gene; Receptor; Biochemistry","score_opus":0.020297997845566417,"score_gpt":0.2768710550520944,"score_spread":0.256573057206528,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391609953","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7880123,0.0053264108,0.20551635,0.00013348603,0.0008693481,0.000092523944,0.00000351463,0.000003889617,0.00004215559],"genre_scores_gemma":[0.99734235,0.000042451837,0.0019708478,0.000028180162,0.00034341338,0.0000029764385,0.000007351989,0.000017969573,0.00024446906],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998846,0.00011756715,0.00040335595,0.00014862091,0.0003559975,0.00012844779],"domain_scores_gemma":[0.999271,0.000011164906,0.00023931736,0.00015978845,0.0002708642,0.000047879035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005094762,0.000111704234,0.00015216491,0.000092501985,0.000059389404,0.000029315825,0.00015907068,0.00011611926,0.00009320072],"category_scores_gemma":[0.00018378395,0.00007635675,0.000382855,0.0002131079,0.00004518682,0.000009976802,0.00004909552,0.0001659253,0.0000031585996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007867762,0.000021743204,0.000028467588,0.000031101605,0.00015387713,0.0000026954117,0.000016020127,0.0026783708,0.9951765,0.00057573133,0.0004554128,0.0007814021],"study_design_scores_gemma":[0.00023399272,0.00014282505,0.00023153258,0.0001812117,0.00007730262,0.000057273195,0.000059300313,0.0014663674,0.99501216,0.0006459851,0.0018043189,0.000087733664],"about_ca_topic_score_codex":0.000009700646,"about_ca_topic_score_gemma":8.086753e-7,"teacher_disagreement_score":0.20933002,"about_ca_system_score_codex":0.000049707516,"about_ca_system_score_gemma":0.00022667192,"threshold_uncertainty_score":0.3113738},"labels":[],"label_agreement":null},{"id":"W4391658342","doi":"10.1016/j.bpj.2023.11.3176","title":"Inhibition of HCN1 by norquetiapine—an active metabolite of the atypical anti-psychotic drug quetiapine","year":2024,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Quetiapine; Schizophrenia (object-oriented programming); Bipolar disorder; Drug; Pharmacology; Quetiapine Fumarate; Active metabolite; Anxiety; Antipsychotic; Metabolite; Atypical antipsychotic; Chemistry; Psychosis; Neuroscience; Medicine; Psychiatry; Psychology; Biochemistry; Lithium (medication)","score_opus":0.006381454928229249,"score_gpt":0.2462569726704482,"score_spread":0.23987551774221894,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391658342","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955818,0.0005970451,0.0029980831,0.0002495448,0.0003799645,0.00008297789,0.00004699657,0.0000055235737,0.000058050828],"genre_scores_gemma":[0.99876505,0.00020688621,0.00023254131,0.00006155948,0.000590776,0.000002234748,0.00002732279,0.000018711253,0.00009490955],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989893,0.0001244732,0.00028890237,0.00020575155,0.00023112878,0.00016047519],"domain_scores_gemma":[0.99948555,0.000011453952,0.00012308275,0.00018099789,0.000108422966,0.000090475514],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015462447,0.00013136241,0.0001995532,0.000033688375,0.000059225415,0.000031603122,0.00017033578,0.000090074995,0.000059008842],"category_scores_gemma":[0.000021232741,0.00008544678,0.00026364805,0.00014401347,0.0001105143,0.000012952685,0.000051829054,0.00022550824,0.0000031099923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009426868,0.00013751457,0.000020513424,0.00002431517,0.0000777324,0.0000016551862,0.00007856333,0.000017525206,0.9960125,0.00080132415,0.0006944759,0.0020396144],"study_design_scores_gemma":[0.00023633201,0.00018781217,0.00050895126,0.000075962016,0.000049289432,0.000022860124,0.000053043448,0.00020200519,0.9959377,0.00050613907,0.00211904,0.000100863654],"about_ca_topic_score_codex":0.000006636828,"about_ca_topic_score_gemma":8.699962e-7,"teacher_disagreement_score":0.0031832452,"about_ca_system_score_codex":0.000009529119,"about_ca_system_score_gemma":0.00006154332,"threshold_uncertainty_score":0.34844187},"labels":[],"label_agreement":null},{"id":"W4391658370","doi":"10.1016/j.bpj.2023.11.2931","title":"The binary-switch model of the adenosine A2A receptor: A molecular dynamics study","year":2024,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Allosteric regulation; G protein-coupled receptor; Molecular switch; Chemistry; Biophysics; Receptor; Molecular dynamics; Energy landscape; Biological system; Physics; Biology; Molecule; Biochemistry; Computational chemistry","score_opus":0.008815078349956372,"score_gpt":0.24559086941228267,"score_spread":0.2367757910623263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391658370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875256,0.0005468132,0.010392375,0.00067359494,0.00057784875,0.00016819482,0.000014397539,0.000007876127,0.00009329835],"genre_scores_gemma":[0.99874437,0.0001139919,0.00022903921,0.000050912626,0.00035689992,0.000007336217,0.0000042589277,0.000026681524,0.00046653074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890953,0.00010028189,0.00026058886,0.0002064187,0.00031118107,0.00021197642],"domain_scores_gemma":[0.9994384,0.000017192991,0.000083298546,0.00029616748,0.000094580166,0.0000703515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027912934,0.00014499242,0.000131098,0.000021060936,0.0002348381,0.00011661459,0.00043468055,0.00007887989,0.000012918404],"category_scores_gemma":[0.0000318539,0.000075893855,0.00026445184,0.0001483758,0.00008047113,0.0000049811256,0.00016819283,0.00029313282,0.0000055259643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004249482,0.0001255491,0.000025153675,0.000006776519,0.00011582976,0.0000046128366,0.00008770073,0.0012705226,0.9938887,0.001989409,0.0005106038,0.001932653],"study_design_scores_gemma":[0.00037671087,0.00086470996,0.000061392,0.000065573666,0.00009730657,0.00003801006,0.0005173765,0.11173225,0.88292754,0.0012066287,0.0018845961,0.00022793],"about_ca_topic_score_codex":0.0000041598837,"about_ca_topic_score_gemma":0.0000028870684,"teacher_disagreement_score":0.11096118,"about_ca_system_score_codex":0.000037297945,"about_ca_system_score_gemma":0.00015809326,"threshold_uncertainty_score":0.30948618},"labels":[],"label_agreement":null},{"id":"W4391955837","doi":"10.1021/acs.biochem.3c00647","title":"Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3","year":2024,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"National Health and Medical Research Council; Australian Research Council; Medical Research Council","keywords":"G protein-coupled receptor; Orphan receptor; Chemistry; Receptor; Ligand (biochemistry); Drug discovery; Plasma protein binding; Transmembrane protein; Transmembrane domain; Cell biology; Biophysics; Biochemistry; Biology; Gene; Transcription factor","score_opus":0.006814473975329827,"score_gpt":0.22325655379410195,"score_spread":0.21644207981877212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391955837","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99636,0.00078145583,0.0012881594,0.00017296907,0.00035437362,0.00020670955,0.000018227112,0.000024813044,0.00079327077],"genre_scores_gemma":[0.99363697,0.000035088695,0.0003171599,0.000042673728,0.00054362736,0.000036401056,0.00006115386,0.000026264917,0.0053006546],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990783,0.00002373456,0.0002035121,0.00032989614,0.00020014125,0.00016445055],"domain_scores_gemma":[0.9994307,0.0000064081987,0.000073525145,0.00037647624,0.00006601102,0.000046838682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017051997,0.00014521701,0.00010271039,0.000016636432,0.00006029361,0.00003452716,0.00024861834,0.00020203198,0.00026770117],"category_scores_gemma":[0.000066810804,0.000107897424,0.00014063985,0.00011685835,0.000048730613,0.000003638248,0.000113801856,0.00011470632,0.000010374511],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002546721,0.000026904952,0.000027367016,0.000116325085,0.00004260479,2.714449e-7,0.000021093863,0.000011071417,0.99765223,0.000089539586,0.0008861421,0.001100991],"study_design_scores_gemma":[0.0001320085,0.000044808658,0.00001060749,0.00013664587,0.000009629249,0.0000039388583,0.00005330609,0.00014786686,0.989538,0.000048216465,0.00974136,0.0001336075],"about_ca_topic_score_codex":0.000014276809,"about_ca_topic_score_gemma":8.7099943e-7,"teacher_disagreement_score":0.008855218,"about_ca_system_score_codex":0.00002716976,"about_ca_system_score_gemma":0.00014629171,"threshold_uncertainty_score":0.4399929},"labels":[],"label_agreement":null},{"id":"W4392001908","doi":"10.1038/s41598-024-54871-7","title":"Dynamic hydrogen peroxide levels reveal a rate-dependent sensitivity in B-cell lymphoma signaling","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Phenomenome Discoveries (Canada)","funders":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Radboud Universiteit","keywords":"Hydrogen peroxide; Lymphoma; Sensitivity (control systems); Signal transduction; Chemistry; Biology; Medicine; Computational biology; Immunology; Biochemistry; Engineering","score_opus":0.009609997213785094,"score_gpt":0.238760906161875,"score_spread":0.22915090894808993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392001908","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99249136,0.0012483222,0.0026035774,0.000039054885,0.002988285,0.00022944757,0.000008505324,0.00004294106,0.00034850158],"genre_scores_gemma":[0.9933049,0.000009468911,0.0005621459,0.000034880828,0.00008290452,0.000016211621,0.00009672116,0.000036441383,0.005856301],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975512,0.0001282569,0.0004700225,0.0011258035,0.00031578296,0.00040891074],"domain_scores_gemma":[0.9991405,0.000018564551,0.00010540142,0.0005467003,0.000073935626,0.00011488365],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0031757383,0.00020553227,0.00019474508,0.00015721713,0.00015155648,0.000300226,0.00009745804,0.00015947544,0.00007612713],"category_scores_gemma":[0.00006630535,0.00019584488,0.00015852737,0.00028552962,0.00007715903,0.000014302374,0.00012869772,0.00009951321,0.000031609623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000088467195,0.000059902904,0.000141078,0.00004254477,0.000016516398,0.0015686738,0.00011690772,0.0010142459,0.9951867,0.000008443849,0.0003318064,0.0015043322],"study_design_scores_gemma":[0.0001596106,0.000034721554,0.00008896651,0.00007541507,0.000013653694,0.00040367784,0.00009867747,0.002095112,0.99188113,0.0010266268,0.0038735173,0.0002488855],"about_ca_topic_score_codex":0.00004435973,"about_ca_topic_score_gemma":0.00010163357,"teacher_disagreement_score":0.0055078,"about_ca_system_score_codex":0.00008036015,"about_ca_system_score_gemma":0.00030290135,"threshold_uncertainty_score":0.79863226},"labels":[],"label_agreement":null},{"id":"W4392189893","doi":"10.1101/2024.02.21.581451","title":"Development of novel tools for dissection of central versus peripheral dopamine D <sub>2</sub> -like receptor signaling in dysglycemia","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Diabetes Canada; University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute on Drug Abuse; United States Drug Enforcement Administration; U.S. Department of Veterans Affairs; National Institutes of Health; U.S. Department of Justice; Pittsburgh Foundation; U.S. Department of Defense","keywords":"Peripheral; Dopamine; Receptor; Dissection (medical); Dopamine receptor; Medicine; Internal medicine; Anatomy","score_opus":0.018978910357267523,"score_gpt":0.23345922090117993,"score_spread":0.21448031054391242,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392189893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98268515,0.00070609053,0.013210829,0.000011304412,0.0023523797,0.0007266264,0.00026995578,0.000035785473,0.0000018790164],"genre_scores_gemma":[0.958404,0.00010758126,0.04075607,0.000010621572,0.0004140682,0.00018155725,0.000013033298,0.00011130805,0.0000017654738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99744815,0.00004208655,0.00088537537,0.0008548681,0.0002683155,0.00050120044],"domain_scores_gemma":[0.99862283,0.000038977425,0.0004219841,0.00047467137,0.0003064717,0.00013507338],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004762786,0.00046084836,0.00055655383,0.0001827313,0.00006317213,0.000075777236,0.0003215239,0.0006161436,0.000014631835],"category_scores_gemma":[0.00017195538,0.00050779205,0.00024654888,0.00024784353,0.000060520797,0.000012428149,0.0003677073,0.00035659943,0.0000013407171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00062422483,0.00016654238,0.00012581891,0.0008574077,0.00022453553,0.000001898804,0.00003452654,0.0009041061,0.9968598,0.00013000774,0.000023740597,0.000047379028],"study_design_scores_gemma":[0.0013328815,0.00018330429,0.0005343978,0.0005834311,0.000066046254,1.4712891e-8,0.000026233107,0.0004809451,0.9953132,7.332786e-7,0.00096840534,0.00051039684],"about_ca_topic_score_codex":0.000008797966,"about_ca_topic_score_gemma":0.0000136209055,"teacher_disagreement_score":0.02754524,"about_ca_system_score_codex":0.00018382506,"about_ca_system_score_gemma":0.00085583376,"threshold_uncertainty_score":0.9997374},"labels":[],"label_agreement":null},{"id":"W4392288047","doi":"10.5530/pj.2024.16.8","title":"Predictive Simulation and Functional Insights of Serotonin Transporter: Ligand Interactions Explored through Database Analysis","year":2024,"lang":"en","type":"article","venue":"Pharmacognosy Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Innovation Cluster (Canada)","funders":"","keywords":"Serotonin transporter; Serotonin Plasma Membrane Transport Proteins; Transporter; Paroxetine; Ligand (biochemistry); Chemistry; Serotonin; In silico; Hydrogen bond; Stereochemistry; Biochemistry; Receptor; Molecule","score_opus":0.03564194442728115,"score_gpt":0.32635496690729004,"score_spread":0.2907130224800089,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392288047","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73147327,0.0022455244,0.26569128,0.000037623577,0.00034958764,0.00007651036,0.000057543977,0.000008294843,0.000060403887],"genre_scores_gemma":[0.99753356,0.0010932183,0.0006270806,0.000049440983,0.00042903458,0.0000063746434,0.00018913846,0.000013459329,0.00005870933],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999194,0.000050148406,0.0002738844,0.0002174728,0.00015704797,0.000107441854],"domain_scores_gemma":[0.99962276,0.000033088094,0.00008273735,0.00007087917,0.00011255793,0.000077969344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013822324,0.00011468864,0.00013964355,0.00013768762,0.00010589313,0.000051164425,0.000049893133,0.000042630603,0.0002926874],"category_scores_gemma":[0.000010838284,0.00009773643,0.00015630737,0.00020588796,0.000030552277,0.000052084077,0.000020446603,0.00017721015,0.0000013858202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021099759,0.000051764557,0.0006983604,0.000026161646,0.0013728251,0.0000143215575,0.0006175393,0.0313601,0.96424854,0.00003148673,0.00024381322,0.0011240671],"study_design_scores_gemma":[0.00056730193,0.00014098537,0.0005549572,0.00006589112,0.00099365,0.000056131517,0.00023626183,0.078633785,0.9081514,0.00024302615,0.010213059,0.0001435623],"about_ca_topic_score_codex":0.000005445491,"about_ca_topic_score_gemma":0.000004422174,"teacher_disagreement_score":0.2660603,"about_ca_system_score_codex":0.000010019759,"about_ca_system_score_gemma":0.000049488983,"threshold_uncertainty_score":0.3985576},"labels":[],"label_agreement":null},{"id":"W4392353996","doi":"10.1101/2024.02.27.582279","title":"Multiple triggers converge to preferential effector coupling in the CB2R through a complex allosteric communication network","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Instituto de Salud Carlos III; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Allosteric regulation; Computational biology; Effector; G protein-coupled receptor; Drug discovery; Signal transduction; Biology; Mutagenesis; Receptor; Neuroscience; Cell biology; Bioinformatics; Mutant; Genetics; Gene","score_opus":0.022175919955541305,"score_gpt":0.2461165091103061,"score_spread":0.2239405891547648,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392353996","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903092,0.0027304026,0.0039798003,0.0002150563,0.001119582,0.0014333158,0.00011916546,0.000082742714,0.000010728034],"genre_scores_gemma":[0.99235666,0.00038143783,0.005450497,0.00053827115,0.0007304444,0.00040855643,0.000013671513,0.00011588774,0.000004601862],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99745876,0.00028107935,0.0005363296,0.0008890852,0.00029562163,0.0005391404],"domain_scores_gemma":[0.9980125,0.00008484368,0.00021761266,0.0014070668,0.000164264,0.000113748494],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00087883195,0.0004954368,0.00046028412,0.00008464031,0.00017350653,0.00027707638,0.0009717363,0.0005142925,0.000052612228],"category_scores_gemma":[0.00012393037,0.00043797315,0.00021103032,0.00036961003,0.00006457973,0.0000075772255,0.0011216655,0.0007100577,0.000060898805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013548956,0.00007545305,0.0006252959,0.000239351,0.00014546288,0.0000072280786,0.00005363151,0.0060586655,0.99051046,0.0001916511,0.0019561304,0.0000011829866],"study_design_scores_gemma":[0.0017271593,0.00046045374,0.0066385735,0.001467139,0.00029237472,8.777567e-8,0.00005099243,0.021170951,0.9079702,0.000021590067,0.058306348,0.001894172],"about_ca_topic_score_codex":0.000115164345,"about_ca_topic_score_gemma":0.000051932842,"teacher_disagreement_score":0.082540296,"about_ca_system_score_codex":0.00008001983,"about_ca_system_score_gemma":0.00023863422,"threshold_uncertainty_score":0.9998072},"labels":[],"label_agreement":null},{"id":"W4392624771","doi":"10.1101/2024.03.08.584132","title":"Blocking Src-PSD-95 interaction rescues glutamatergic signaling dysregulation in schizophrenia","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"","keywords":"Proto-oncogene tyrosine-protein kinase Src; NMDA receptor; Schizophrenia (object-oriented programming); Glutamatergic; Postsynaptic density; Neuroscience; Postsynaptic potential; Cell biology; Receptor; Biology; Kinase; Psychology; Glutamate receptor; Genetics; Psychiatry","score_opus":0.010326733445930934,"score_gpt":0.22826239674537938,"score_spread":0.21793566329944844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392624771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99168015,0.0042344094,0.0010271935,0.000081471764,0.0022617113,0.00048256072,0.00005651518,0.00016727325,0.000008709081],"genre_scores_gemma":[0.9943581,0.0004410022,0.0034998695,0.00006703002,0.0013323327,0.00010735928,0.0000049020614,0.00017851817,0.000010869945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969345,0.00017824557,0.00072960195,0.0012953576,0.0003318155,0.00053053076],"domain_scores_gemma":[0.99844795,0.000020438158,0.00032686105,0.0008179444,0.00023445376,0.00015233608],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006740358,0.0006007717,0.00047900985,0.00034135568,0.00012241893,0.0003884923,0.00040749786,0.0008461031,0.0000696395],"category_scores_gemma":[0.00010550375,0.00065721245,0.00023316272,0.0003477196,0.00004996247,0.000017625693,0.000756984,0.00085606193,0.000047889862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012263912,0.000049319493,0.0004076288,0.0003247429,0.000117836964,0.000033622648,0.000013419303,0.0035528583,0.9949805,0.00029148173,0.00008903743,0.000016898352],"study_design_scores_gemma":[0.00044656135,0.000072300536,0.0014600988,0.0012348769,0.00007941535,8.361938e-8,0.000009123839,0.005085204,0.9892617,0.00004656799,0.001547206,0.00075687206],"about_ca_topic_score_codex":0.000070678674,"about_ca_topic_score_gemma":0.00001312651,"teacher_disagreement_score":0.005718825,"about_ca_system_score_codex":0.00016091426,"about_ca_system_score_gemma":0.0003260901,"threshold_uncertainty_score":0.9995879},"labels":[],"label_agreement":null},{"id":"W4392845131","doi":"10.22541/au.161144035.53972444/v2","title":"Seeing Beyond the Blot: A Critical Look at  Assumptions and Raw Data Interpretation in Western Blotting","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universität Innsbruck; Medizinische Universität Innsbruck; University of Alberta; National Science Foundation","keywords":"Blot; Raw data; Leverage (statistics); Normalization (sociology); Data science; Computational biology; Experimental data; Computer science; Data mining; Biochemical engineering; Biology; Engineering; Artificial intelligence; Mathematics","score_opus":0.02568974749300976,"score_gpt":0.32170702823069935,"score_spread":0.29601728073768957,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392845131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9564907,0.0073886462,0.031250063,0.0018595235,0.0008578389,0.00041793648,0.0001041705,0.000036620222,0.0015945245],"genre_scores_gemma":[0.9957351,0.00028211137,0.0016594678,0.0003807434,0.00027532122,0.000035045974,0.0005472916,0.000034320918,0.001050583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985488,0.00009907042,0.00030027976,0.000721432,0.0001246473,0.00020574128],"domain_scores_gemma":[0.9991319,0.00007112472,0.000049138464,0.0006586585,0.000037071597,0.000052087278],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005475403,0.0002011058,0.00017500317,0.000054492713,0.0000907723,0.00019564052,0.00037172693,0.00027800383,0.00008070907],"category_scores_gemma":[0.00015411103,0.00015237549,0.00005765633,0.000037492257,0.000075303426,0.0000043133364,0.004539904,0.0004136375,0.0000147546625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009792154,0.0000948835,0.0024767779,0.00094155164,0.00033558975,0.00005256397,0.0018616114,0.0011832541,0.9677928,0.0024833067,0.0026866756,0.01999305],"study_design_scores_gemma":[0.0017693697,0.00053379894,0.0013215536,0.0036880397,0.0011937866,0.0005380377,0.0034035102,0.43983802,0.46368694,0.046876114,0.0336512,0.0034996222],"about_ca_topic_score_codex":0.000055960532,"about_ca_topic_score_gemma":0.0005809769,"teacher_disagreement_score":0.50410587,"about_ca_system_score_codex":0.000023435787,"about_ca_system_score_gemma":0.00006341238,"threshold_uncertainty_score":0.62136924},"labels":[],"label_agreement":null},{"id":"W4392900446","doi":"10.1101/2024.03.18.585390","title":"Diffusion and Oligomerization States of the Muscarinic M1 Receptor in Live Cells − The Impact of Ligands and Membrane Disruptors","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Medical Research Council; Natural Sciences and Engineering Research Council of Canada; University of Toronto","keywords":"Muscarinic acetylcholine receptor; Diffusion; Membrane; Chemistry; Cell biology; Biophysics; Receptor; Biochemistry; Physics; Biology; Thermodynamics","score_opus":0.005274293879160317,"score_gpt":0.2144741969250172,"score_spread":0.2091999030458569,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392900446","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99624324,0.0026713216,0.000049239618,0.00003877695,0.00037855908,0.00042595287,0.00018098281,0.00001022057,0.0000017048753],"genre_scores_gemma":[0.9957218,0.0039633266,0.00011911607,0.000013357881,0.00010289106,0.000024502488,0.0000012706274,0.00004855521,0.00000515907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99869555,0.0000933864,0.0003890256,0.00046739427,0.00015513615,0.00019950984],"domain_scores_gemma":[0.99896985,0.0000393572,0.00029476528,0.0005059787,0.0001226305,0.00006742],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035127398,0.00028606007,0.00033470674,0.0000854773,0.0000556799,0.00005264746,0.00024541846,0.00031437684,0.000016363643],"category_scores_gemma":[0.000077179066,0.00018015526,0.0001422022,0.00021122393,0.00015495719,0.000004795403,0.0007447762,0.00029244716,6.6768814e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034890316,0.000039707564,0.0069483886,0.0002806345,0.00009716622,5.9311907e-7,0.00008607073,0.00022554309,0.9922241,0.00004055011,0.000016834432,0.0000055092023],"study_design_scores_gemma":[0.0002158879,0.000112283815,0.024301143,0.00035497328,0.00005306073,1.4961957e-8,0.000025495377,0.000651502,0.9740301,0.0000069926273,0.00005263202,0.00019593543],"about_ca_topic_score_codex":0.00019410644,"about_ca_topic_score_gemma":0.0000074281393,"teacher_disagreement_score":0.018194033,"about_ca_system_score_codex":0.000025744395,"about_ca_system_score_gemma":0.00018859262,"threshold_uncertainty_score":0.7346518},"labels":[],"label_agreement":null},{"id":"W4392921638","doi":"10.1080/10408363.2023.2286606","title":"G protein-coupled receptor (GPCR) gene variants and human genetic disease","year":2024,"lang":"en","type":"review","venue":"Critical Reviews in Clinical Laboratory Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal; University of Toronto; Toronto Western Hospital","funders":"H. Lundbeck A/S; Lundbeckfonden; McGill University","keywords":"G protein-coupled receptor; Biology; Receptor; Genetics; 5-HT5A receptor; Gene","score_opus":0.11193756265412577,"score_gpt":0.45876744052961127,"score_spread":0.34682987787548547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392921638","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010498852,0.99632984,0.0001517576,0.00007290693,0.00089487573,0.0013007183,0.00012281506,0.000018631834,0.00005859196],"genre_scores_gemma":[0.00022843717,0.99407625,0.0038256044,0.00026631224,0.0009946319,0.00036273277,0.000050334802,0.000054154196,0.00014153926],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99380445,0.0012996008,0.0022093167,0.0017503243,0.0003575315,0.00057879684],"domain_scores_gemma":[0.9981223,0.00025929642,0.0002628826,0.0006343052,0.00011321455,0.00060804863],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0051016123,0.0005842219,0.0018984493,0.0001302845,0.0002212992,0.0002486068,0.00075864454,0.00058580807,0.00020624191],"category_scores_gemma":[0.006409198,0.0004060166,0.00055669405,0.00067555415,0.0012126229,0.000014867047,0.0004091669,0.0006801325,0.00017491958],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039098686,0.00083941896,0.0002048146,0.061361566,0.00019467824,0.0002826252,0.000020039772,0.000001005159,0.006096415,0.025644839,0.004542202,0.9007733],"study_design_scores_gemma":[0.000102813814,0.00037202743,0.000012698493,0.012702657,0.0003585146,0.0000041341614,0.0000043596892,0.00001617664,0.000024144934,0.00091656105,0.98491305,0.0005728808],"about_ca_topic_score_codex":0.000002954225,"about_ca_topic_score_gemma":0.000004871331,"teacher_disagreement_score":0.9803708,"about_ca_system_score_codex":0.000027250268,"about_ca_system_score_gemma":0.0009074946,"threshold_uncertainty_score":0.9998392},"labels":[],"label_agreement":null},{"id":"W4393156427","doi":"10.1101/2024.03.22.24304728","title":"Large-scale Mendelian randomization identifies novel pathways as therapeutic targets for heart failure with reduced ejection fraction and with preserved ejection fraction","year":2024,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Circle Cardiovascular Imaging; Barts Health NHS Trust; British Heart Foundation; Engineering and Physical Sciences Research Council; U.S. Department of Veterans Affairs; National Institute for Health and Care Research; St George's University Hospitals NHS Foundation Trust; UK Research and Innovation; Queen Mary University of London; Office of Research and Development","keywords":"Ejection fraction; Mendelian randomization; Fraction (chemistry); Heart failure; Cardiology; Internal medicine; Medicine; Randomization; Clinical trial; Biology; Chemistry; Gene; Genetics; Genetic variants","score_opus":0.014207145515034532,"score_gpt":0.25174036225032803,"score_spread":0.2375332167352935,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393156427","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.70904565,0.00075414754,0.28802556,0.00020128314,0.00064466946,0.0011419965,0.00004658951,0.000069589856,0.00007054894],"genre_scores_gemma":[0.99325955,0.00022222461,0.003892162,0.000068252404,0.00058957067,0.00055559736,0.00091483904,0.000098784534,0.00039903162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815536,0.00010384589,0.000313442,0.00089212577,0.00026264694,0.000272609],"domain_scores_gemma":[0.9990098,0.000024838739,0.0002611595,0.00033953766,0.00028585395,0.00007879423],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00056158757,0.00036526454,0.0003573116,0.00014997448,0.00025847778,0.00022889921,0.00009346065,0.00050827005,0.000043070777],"category_scores_gemma":[0.00004526137,0.00029271317,0.00013555106,0.00012305305,0.000034583743,0.00002554137,0.00011142728,0.00038651554,0.0000040717778],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0016985614,0.00008453253,0.0007200853,0.00027781125,0.00029291923,6.5792676e-7,0.00012046624,0.0013462248,0.9950188,0.000039375438,0.00026848784,0.00013212016],"study_design_scores_gemma":[0.0030955358,0.000744928,0.00039030585,0.00027335464,0.000343675,0.000026879758,0.0013088337,0.0071501727,0.97528356,0.0017078753,0.009159005,0.0005158799],"about_ca_topic_score_codex":0.000054376076,"about_ca_topic_score_gemma":0.00020887962,"teacher_disagreement_score":0.2842139,"about_ca_system_score_codex":0.000056691737,"about_ca_system_score_gemma":0.00011729576,"threshold_uncertainty_score":0.9999525},"labels":[],"label_agreement":null},{"id":"W4393156617","doi":"10.1101/2024.03.23.586386","title":"Structural insights into the agonist selectivity and structure-based engineering of the adenosine A3 receptor","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"Exploratory Research for Advanced Technology; Japan Society for the Promotion of Science; Ono Medical Research Foundation; Kao Foundation for Arts and Sciences; Japan Agency for Medical Research and Development; Uehara Memorial Foundation","keywords":"Agonist; Adenosine receptor; Adenosine; Chemistry; Receptor; Functional selectivity; Selectivity; Pharmacology; Neuroscience; Biophysics; Biology; Biochemistry","score_opus":0.004934832896205002,"score_gpt":0.1890500371595349,"score_spread":0.1841152042633299,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393156617","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888094,0.00841145,0.0004891474,0.00019050637,0.0014838591,0.0004695036,0.00009701994,0.00004795449,0.0000011676747],"genre_scores_gemma":[0.9974842,0.00012760833,0.001616492,0.00008605748,0.00055165606,0.00003493337,0.0000012863457,0.000093520735,0.000004224714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982285,0.000119872544,0.00034997202,0.0007339869,0.0002735806,0.00029407153],"domain_scores_gemma":[0.9984953,0.000029510464,0.00024044985,0.0009052657,0.00022855664,0.00010090785],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00021154727,0.00045922236,0.000349302,0.000079911966,0.00020489402,0.00016133927,0.000540948,0.00048366483,0.000020071635],"category_scores_gemma":[0.00014564475,0.0003040351,0.00017601026,0.00028248233,0.00015709235,0.0000053123167,0.00079288596,0.00071736,0.000001271159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022733768,0.000009587714,0.00045394886,0.00039495388,0.00013791585,0.000001303176,0.000025059462,0.00093241996,0.99754876,0.00039220232,0.000075712924,0.0000054287843],"study_design_scores_gemma":[0.00018372046,0.000054416207,0.003981621,0.00021314879,0.00009191209,2.7336649e-8,0.0000025021484,0.0022041777,0.9903115,0.000020215386,0.0025637152,0.00037301233],"about_ca_topic_score_codex":0.000055170232,"about_ca_topic_score_gemma":0.000015364692,"teacher_disagreement_score":0.00867483,"about_ca_system_score_codex":0.00005800361,"about_ca_system_score_gemma":0.00043694975,"threshold_uncertainty_score":0.9999412},"labels":[],"label_agreement":null},{"id":"W4393386594","doi":"10.1515/bmc-2022-0047","title":"Seeing beyond the blot: A critical look at assumptions and raw data interpretation in Western blotting","year":2024,"lang":"en","type":"article","venue":"BioMolecular Concepts","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universität Innsbruck; Medizinische Universität Innsbruck; University of Alberta; National Science Foundation","keywords":"Blot; Raw data; Leverage (statistics); Computational biology; Data science; Normalization (sociology); Experimental data; Computer science; Biochemical engineering; Data mining; Biology; Engineering; Artificial intelligence; Biochemistry; Mathematics","score_opus":0.01991902734556596,"score_gpt":0.33505114911323497,"score_spread":0.315132121767669,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393386594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8539699,0.018032724,0.1259178,0.0009793693,0.00045271768,0.00027072328,0.0000434163,0.000036293935,0.00029704673],"genre_scores_gemma":[0.9981815,0.00012515385,0.00071566703,0.00041624377,0.00014461225,0.000017078408,0.00018636908,0.000026383073,0.00018699125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99881595,0.00012245587,0.00020854097,0.00050221564,0.00013047636,0.0002203588],"domain_scores_gemma":[0.9994245,0.00005916154,0.000024833766,0.00040444173,0.00002865058,0.000058415542],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037232097,0.00013981997,0.00010829305,0.000047682,0.000113685324,0.00014841637,0.00024193911,0.00011091233,0.000042758464],"category_scores_gemma":[0.0001398724,0.00011352238,0.00004701235,0.000101482576,0.00013411815,0.000014995927,0.0004464657,0.00010787385,0.000016518958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001528837,0.000012203903,0.00035713246,0.00003715741,0.00003668251,0.000049399605,0.0003735155,0.000015592046,0.9909342,0.00051338616,0.00021286772,0.007442583],"study_design_scores_gemma":[0.0009755172,0.0003608124,0.00064211857,0.00056528905,0.00018620197,0.0004445814,0.0009029448,0.061665386,0.8539302,0.00090782734,0.07854691,0.0008722566],"about_ca_topic_score_codex":0.000016453272,"about_ca_topic_score_gemma":0.00007421712,"teacher_disagreement_score":0.1442116,"about_ca_system_score_codex":0.000018950626,"about_ca_system_score_gemma":0.000044771205,"threshold_uncertainty_score":0.46293083},"labels":[],"label_agreement":null},{"id":"W4393742850","doi":"10.5281/zenodo.8049259","title":"Molecular dynamics trajectories for \"Reservoir-REMD facilitates kinetic rescue from metastable peptide conformations","year":2023,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Metastability; Molecular dynamics; Dynamics (music); Peptide; Kinetic energy; Chemistry; Computational biology; Physics; Biology; Computational chemistry; Classical mechanics; Biochemistry","score_opus":0.023746442925672056,"score_gpt":0.24662309963348522,"score_spread":0.22287665670781318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393742850","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0038848561,0.00023691611,0.012053798,0.0001265561,0.00027003748,0.00081700203,0.98191303,0.00018458047,0.00051321334],"genre_scores_gemma":[0.0018717952,0.00029631838,0.0005053275,0.00007209675,0.00021690666,0.0000010441413,0.9952093,0.000922214,0.0009050228],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977863,0.0002429896,0.00044303088,0.0006457417,0.0003667288,0.0005152212],"domain_scores_gemma":[0.99814445,0.000038038615,0.00016866585,0.0007983025,0.00067208224,0.00017845625],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000566604,0.00032426443,0.00031366645,0.0001961628,0.0012110958,0.00065335305,0.0012352112,0.00027979925,0.0017480414],"category_scores_gemma":[0.0011129454,0.00034786417,0.00018454433,0.00028359896,0.000121279045,0.000023252225,0.0009713073,0.00029218654,0.0020854687],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008207231,0.000047204274,4.493033e-8,0.00015382843,0.00020865306,0.0000049505143,0.00009989928,0.000888058,0.03915017,0.0002176241,0.95821303,0.0009344348],"study_design_scores_gemma":[0.00047879986,0.00037513327,0.0000032838418,0.000046054665,0.00008613083,0.000010098229,0.00046389273,0.00081659015,0.008624871,0.00025780627,0.9884679,0.00036947583],"about_ca_topic_score_codex":0.00038824003,"about_ca_topic_score_gemma":0.00003069483,"teacher_disagreement_score":0.030525299,"about_ca_system_score_codex":0.0001162379,"about_ca_system_score_gemma":0.000023546398,"threshold_uncertainty_score":0.99989736},"labels":[],"label_agreement":null},{"id":"W4393879358","doi":"10.5281/zenodo.8049258","title":"Molecular dynamics trajectories for \"Reservoir-REMD facilitates kinetic rescue from metastable peptide conformations","year":2023,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Metastability; Molecular dynamics; Kinetic energy; Peptide; Dynamics (music); Chemistry; Chemical physics; Physics; Computational chemistry; Classical mechanics; Biochemistry","score_opus":0.023746442925672056,"score_gpt":0.24662309963348522,"score_spread":0.22287665670781318,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393879358","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0038848561,0.00023691611,0.012053798,0.0001265561,0.00027003748,0.00081700203,0.98191303,0.00018458047,0.00051321334],"genre_scores_gemma":[0.0018717952,0.00029631838,0.0005053275,0.00007209675,0.00021690666,0.0000010441413,0.9952093,0.000922214,0.0009050228],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977863,0.0002429896,0.00044303088,0.0006457417,0.0003667288,0.0005152212],"domain_scores_gemma":[0.99814445,0.000038038615,0.00016866585,0.0007983025,0.00067208224,0.00017845625],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000566604,0.00032426443,0.00031366645,0.0001961628,0.0012110958,0.00065335305,0.0012352112,0.00027979925,0.0017480414],"category_scores_gemma":[0.0011129454,0.00034786417,0.00018454433,0.00028359896,0.000121279045,0.000023252225,0.0009713073,0.00029218654,0.0020854687],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008207231,0.000047204274,4.493033e-8,0.00015382843,0.00020865306,0.0000049505143,0.00009989928,0.000888058,0.03915017,0.0002176241,0.95821303,0.0009344348],"study_design_scores_gemma":[0.00047879986,0.00037513327,0.0000032838418,0.000046054665,0.00008613083,0.000010098229,0.00046389273,0.00081659015,0.008624871,0.00025780627,0.9884679,0.00036947583],"about_ca_topic_score_codex":0.00038824003,"about_ca_topic_score_gemma":0.00003069483,"teacher_disagreement_score":0.030525299,"about_ca_system_score_codex":0.0001162379,"about_ca_system_score_gemma":0.000023546398,"threshold_uncertainty_score":0.99989736},"labels":[],"label_agreement":null},{"id":"W4394695508","doi":"10.1101/2024.04.03.588016","title":"Functional Bias of Contractile Control in Mouse Resistance Arteries","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Resistance (ecology); Control (management); Business; Cardiology; Computer science; Biology; Medicine; Artificial intelligence; Ecology","score_opus":0.013085275168639023,"score_gpt":0.20894138266605347,"score_spread":0.19585610749741444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394695508","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99133295,0.004011802,0.0025008298,0.00010747446,0.0010373199,0.0004088262,0.00052532856,0.000051942745,0.00002353195],"genre_scores_gemma":[0.9980611,0.00024313215,0.00086609647,0.000118585594,0.0004223698,0.00011839866,0.0000017788828,0.000084939384,0.000083561274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980086,0.000108530054,0.0005621362,0.00074458215,0.0002483869,0.00032774184],"domain_scores_gemma":[0.99864185,0.000030874424,0.00030171723,0.0006590999,0.0002638025,0.00010268278],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00046650643,0.0003655832,0.00046839722,0.00015921374,0.00004380517,0.00008655751,0.00025021215,0.000528616,0.000080833735],"category_scores_gemma":[0.00015791705,0.00038222835,0.00018947404,0.00014819387,0.0000916327,0.0000059778554,0.00022975595,0.00046395787,0.00001686003],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017517505,0.000071033035,0.000951532,0.00029695296,0.00013012522,0.000016572983,0.0000037439358,0.00020966,0.996531,0.00088024104,0.0007332907,6.865151e-7],"study_design_scores_gemma":[0.00056630856,0.00005016028,0.0039530573,0.00025961458,0.000045607932,1.1737242e-8,0.000004613997,0.00012027549,0.9870125,0.000015420594,0.0075775855,0.00039485775],"about_ca_topic_score_codex":0.0000229596,"about_ca_topic_score_gemma":0.000022112017,"teacher_disagreement_score":0.0095185,"about_ca_system_score_codex":0.000048499413,"about_ca_system_score_gemma":0.0004553248,"threshold_uncertainty_score":0.99986297},"labels":[],"label_agreement":null},{"id":"W4394931123","doi":"10.1021/acsptsci.4c00086","title":"Development of a Fluorescent Ligand for the Intracellular Allosteric Binding Site of the Neurotensin Receptor 1","year":2024,"lang":"en","type":"article","venue":"ACS Pharmacology & Translational Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Université de Montréal; Deutsche Forschungsgemeinschaft; Verband der Chemischen Industrie","keywords":"Allosteric regulation; Allosteric modulator; G protein-coupled receptor; Chemistry; Intracellular; Ligand (biochemistry); Neurotensin receptor; Binding site; Drug discovery; Receptor; Neurotensin; Biochemistry","score_opus":0.018635674451955027,"score_gpt":0.2836444569590039,"score_spread":0.2650087825070489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394931123","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98650736,0.0011484383,0.010322157,0.00088516466,0.0007594534,0.00033795723,0.000025384372,0.0000038188955,0.00001026008],"genre_scores_gemma":[0.9947242,0.0000652095,0.004916911,0.00012371375,0.00008956758,0.000021707478,0.000012022024,0.0000070509404,0.00003960083],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991791,0.00002522297,0.00021624278,0.00022102466,0.00020125894,0.00015715492],"domain_scores_gemma":[0.9996679,0.000059961858,0.000058613932,0.00008482025,0.00010076404,0.000027951326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005813491,0.00007717169,0.00007421873,0.00003741369,0.0002083168,0.000014690713,0.0002734113,0.000042258584,0.000034240733],"category_scores_gemma":[0.000016273087,0.000047130303,0.00006516396,0.00025233405,0.00027386646,0.0000080048085,0.000052921834,0.00006441646,0.000001877794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000036117766,0.000016485177,0.000044767374,0.000020388967,0.000031627413,1.5339307e-7,0.00033496573,0.00034481467,0.9945993,0.00011729201,0.00016767118,0.004286413],"study_design_scores_gemma":[0.00015629012,0.000037937534,0.0003117659,0.00001691361,0.000029400373,0.0000028980758,0.000019267938,0.0019963633,0.9762685,0.000024465255,0.021082135,0.00005408146],"about_ca_topic_score_codex":0.0000010861079,"about_ca_topic_score_gemma":0.0000022719373,"teacher_disagreement_score":0.020914463,"about_ca_system_score_codex":0.000008953553,"about_ca_system_score_gemma":0.00033495433,"threshold_uncertainty_score":0.1921918},"labels":[],"label_agreement":null},{"id":"W4394935967","doi":"10.1016/j.jddst.2024.105686","title":"In vitro and in vivo evaluation of isoxsuprine loaded invasomes for efficient treatment of diabetes‐accelerated atherosclerosis","year":2024,"lang":"en","type":"article","venue":"Journal of Drug Delivery Science and Technology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"Prince Sattam bin Abdulaziz University","keywords":"In vivo; Diabetes mellitus; Bioavailability; Vasodilation; In vitro; Insulin; Pharmacology; Medicine; Chemistry; Internal medicine; Endocrinology; Biology; Biochemistry; Biotechnology","score_opus":0.018931025806220365,"score_gpt":0.2668502489224176,"score_spread":0.24791922311619724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394935967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956363,0.0038806738,0.00004777986,0.00019527653,0.00008199554,0.00014741218,0.000005418533,0.0000013958091,0.000003741422],"genre_scores_gemma":[0.99900526,0.00055575743,0.00040285097,0.000008243805,0.0000123017735,0.0000068611944,5.3632397e-7,0.0000034141979,0.000004767998],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99928296,0.000019283643,0.00026488642,0.00014890564,0.00016077198,0.00012320119],"domain_scores_gemma":[0.9994946,0.000020312467,0.00010548039,0.00006581132,0.00029110233,0.000022703422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009336239,0.000064523214,0.0001737441,0.00046107516,0.0000205146,0.000011156511,0.00008656126,0.000065432505,0.000004650029],"category_scores_gemma":[0.000072935785,0.000049461585,0.000027576649,0.0004137101,0.00017319246,0.000012786201,0.000031170548,0.00003668562,3.9483343e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030515124,0.000064295804,0.0011895406,0.000016708937,0.000012456008,4.32451e-7,0.000101713136,0.00016425288,0.98849356,0.000022980978,0.000005266626,0.009898256],"study_design_scores_gemma":[0.0007643752,0.00049936166,0.0002815259,0.000057182417,0.000021051284,0.0000039247093,0.00026599565,0.009229173,0.9885074,0.00026150295,0.00006452671,0.00004399108],"about_ca_topic_score_codex":0.000008060722,"about_ca_topic_score_gemma":0.000008482631,"teacher_disagreement_score":0.009854265,"about_ca_system_score_codex":0.00004152823,"about_ca_system_score_gemma":0.00018796079,"threshold_uncertainty_score":0.20169848},"labels":[],"label_agreement":null},{"id":"W4395000631","doi":"10.1079/9781800620742.0002","title":"Endocrine Methodologies","year":2024,"lang":"en","type":"book-chapter","venue":"CABI eBooks","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Endocrine system; Medicine; Internal medicine; Hormone","score_opus":0.041456573434366935,"score_gpt":0.28813487144099276,"score_spread":0.24667829800662583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395000631","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001787139,0.004637512,0.0016247648,0.000032302843,0.0009533519,0.00018647213,0.00004929153,0.00006142629,0.9922762],"genre_scores_gemma":[0.0008890632,0.0002175797,0.002897463,0.00016240582,0.00094843627,0.000019337624,0.00011545593,0.00010445602,0.9946458],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989163,0.00001541833,0.00022517188,0.00050260895,0.00012211554,0.00021834108],"domain_scores_gemma":[0.99937636,0.000018333285,0.0000743365,0.00040736864,0.0000547242,0.00006886923],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015326201,0.00031801363,0.00028361366,0.00006375998,0.000045195393,0.00004100779,0.00021022523,0.00038595527,0.00040667047],"category_scores_gemma":[0.000025410174,0.0002817598,0.00027680065,0.0000039463366,0.000078238496,5.211994e-7,0.0002385779,0.00025648516,0.00014318411],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031567517,0.0000018681926,2.529872e-7,0.0001091637,0.0002680603,0.0000832165,0.000031203006,0.0000044233457,0.674687,0.2305872,0.003259216,0.09093679],"study_design_scores_gemma":[0.00006781295,0.00011196815,9.364536e-8,0.000056500205,0.000057706773,0.000033941822,0.0000087919425,0.000001424971,0.24125035,0.04648269,0.7116794,0.0002492948],"about_ca_topic_score_codex":0.0000027474073,"about_ca_topic_score_gemma":0.0000037872928,"teacher_disagreement_score":0.7084202,"about_ca_system_score_codex":0.00001610193,"about_ca_system_score_gemma":0.00006350574,"threshold_uncertainty_score":0.99996346},"labels":[],"label_agreement":null},{"id":"W4395954718","doi":"10.1101/2024.04.25.591166","title":"Combination of Haloperidol with UNC9994, β-arrestin-biased analog of Aripiprazole, ameliorates schizophrenia-related phenotypes induced by NMDAR deficit in mice","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Haloperidol; Aripiprazole; Pharmacology; Agonist; Dopamine receptor D2; Schizophrenia (object-oriented programming); Partial agonist; NMDA receptor; Antipsychotic; Typical antipsychotic; Psychology; Atypical antipsychotic; Dopamine; Medicine; Internal medicine; Neuroscience; Receptor; Psychiatry","score_opus":0.007525806572012149,"score_gpt":0.2049356971629925,"score_spread":0.19740989059098035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395954718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948373,0.0033620878,0.00041223934,0.00004430666,0.00044520496,0.0005749,0.0002563975,0.000053464642,0.000014118696],"genre_scores_gemma":[0.9974943,0.00023285455,0.0019724732,0.000028192339,0.000070519745,0.00006267613,0.0000127938265,0.00012178516,0.0000044386566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973731,0.00015462928,0.0008665188,0.0009033011,0.00033741407,0.00036503948],"domain_scores_gemma":[0.9979815,0.00003080887,0.0006751956,0.0006512747,0.00053899974,0.00012223257],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00051421253,0.0005241616,0.0006788304,0.00033502537,0.00004997443,0.00006540046,0.0004448591,0.0007483619,0.00002734642],"category_scores_gemma":[0.0001651793,0.0005104609,0.00013573364,0.0007036066,0.00012461471,0.000010386182,0.0003349007,0.00063915324,0.0000064413507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024156997,0.00020004532,0.0012587538,0.00045493434,0.00022929488,0.000009116946,0.000013027717,0.00053795497,0.9965011,0.00048746885,0.000058817386,0.00000793131],"study_design_scores_gemma":[0.00105943,0.00031127036,0.0029872013,0.0008338779,0.00012187391,2.9283623e-8,0.000011989401,0.00048855325,0.9935176,0.000019159861,0.00009959074,0.00054942153],"about_ca_topic_score_codex":0.0002846223,"about_ca_topic_score_gemma":0.000022910215,"teacher_disagreement_score":0.0031292334,"about_ca_system_score_codex":0.000055960158,"about_ca_system_score_gemma":0.00068699464,"threshold_uncertainty_score":0.9997347},"labels":[],"label_agreement":null},{"id":"W4396523647","doi":"10.1007/978-981-99-7808-3_14","title":"Von der Natur inspirierte Rechentechniken zur Entwicklung von Medikamenten und Therapeutika","year":2024,"lang":"de","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Emergent BioSolutions (Canada)","funders":"","keywords":"Medicine","score_opus":0.017345194667387525,"score_gpt":0.2691882623987096,"score_spread":0.25184306773132203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396523647","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00517615,0.36791384,0.017717948,0.0032427723,0.013318322,0.0034244042,0.00056750193,0.00054389774,0.5880952],"genre_scores_gemma":[0.14704594,0.06009749,0.0031048567,0.0043443074,0.004192412,0.00012351837,0.00290336,0.0007536995,0.7774344],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9953008,0.00006964904,0.0010556468,0.0019193982,0.0007470764,0.00090740796],"domain_scores_gemma":[0.99773693,0.000040838317,0.00039369985,0.0011563434,0.00030040645,0.0003718027],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.00063661806,0.0013367306,0.0009031812,0.00030592427,0.00023370916,0.00028555127,0.000861827,0.0027738158,0.0054301484],"category_scores_gemma":[0.000030583058,0.0011595287,0.0009317422,0.00010971081,0.00022933433,0.0000132868645,0.00070694543,0.0014330208,0.0009227548],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027712918,0.00010792838,0.000033072196,0.00031401438,0.005452977,0.00012876133,0.00015659479,0.000007665846,0.8803926,0.080721594,0.006383171,0.026024465],"study_design_scores_gemma":[0.00046477327,0.0005668739,0.000001531519,0.00051400455,0.00090036134,0.000028157561,0.000062910294,0.00010202414,0.27871013,0.008054286,0.70950717,0.001087797],"about_ca_topic_score_codex":0.00007811518,"about_ca_topic_score_gemma":0.00007799776,"teacher_disagreement_score":0.703124,"about_ca_system_score_codex":0.00017378891,"about_ca_system_score_gemma":0.00025504956,"threshold_uncertainty_score":0.99993837},"labels":[],"label_agreement":null},{"id":"W4396534697","doi":"10.1021/acs.jpcb.4c01035","title":"Diffusion and Oligomerization States of the Muscarinic M<sub>1</sub> Receptor in Live Cells─The Impact of Ligands and Membrane Disruptors","year":2024,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Medical Research Foundation; Medical Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; G protein-coupled receptor; Biophysics; Allosteric regulation; Fluorescence recovery after photobleaching; Receptor; Lipid raft; Lipid bilayer; Membrane; Biochemistry; Biology","score_opus":0.0035563173858555956,"score_gpt":0.22647192279206194,"score_spread":0.22291560540620634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396534697","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99904746,0.0007391392,0.000037687132,0.000057133486,0.000039183098,0.00005389859,0.000012167559,0.0000010677117,0.000012243064],"genre_scores_gemma":[0.9985394,0.0012607281,0.0000042246547,0.0000049575488,0.00016289855,7.6606943e-7,0.0000038047442,0.000010078489,0.000013141003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99943745,0.00004151571,0.00021896928,0.00008523381,0.00012673995,0.000090081456],"domain_scores_gemma":[0.9995397,0.00008882234,0.00016774207,0.000117923206,0.00004920956,0.00003662696],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022323485,0.00010067782,0.00016192388,0.000010902964,0.000034278106,0.000013739916,0.00013905711,0.000053144347,0.000007290174],"category_scores_gemma":[0.00003816981,0.00004615322,0.0001259419,0.00009621711,0.00012596436,0.0000063276275,0.00008716644,0.0001598144,1.2544439e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007941207,0.000043748045,0.00013520905,0.000078198296,0.000053807504,3.2069917e-7,0.0008109735,0.00051061774,0.99746615,0.0000030985311,0.000020478901,0.00079801446],"study_design_scores_gemma":[0.00018401326,0.00017724936,0.0006003544,0.00012524435,0.000041645075,0.000010440132,0.00030316264,0.0016250394,0.99673694,0.00013045587,0.000012801596,0.000052626165],"about_ca_topic_score_codex":0.000012088538,"about_ca_topic_score_gemma":7.69918e-7,"teacher_disagreement_score":0.0011144216,"about_ca_system_score_codex":0.000010330622,"about_ca_system_score_gemma":0.000043494427,"threshold_uncertainty_score":0.18820737},"labels":[],"label_agreement":null},{"id":"W4396577729","doi":"10.1016/j.str.2024.04.007","title":"The critical importance of conditions: Reconciling GPCR functionality and biophysical findings","year":2024,"lang":"en","type":"article","venue":"Structure","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs","keywords":"G protein-coupled receptor; Computational biology; Chemistry; Biology; Receptor; Biochemistry","score_opus":0.007797602364941687,"score_gpt":0.2716227053254438,"score_spread":0.2638251029605021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396577729","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964623,0.0021215382,0.0004942803,0.0003307317,0.00035551176,0.000044329863,0.00009577095,0.0000073374363,0.0000882434],"genre_scores_gemma":[0.9992376,0.00006438332,0.0002595333,0.00006646415,0.00023402074,0.0000032031662,0.000043508728,0.0000067203123,0.00008455554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995304,0.000017471762,0.000111853406,0.00017459474,0.000073119496,0.000092595445],"domain_scores_gemma":[0.9997654,0.00004946466,0.000013078368,0.00010027498,0.000042555606,0.000029216744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008568457,0.0000649422,0.000063036205,0.000008769532,0.00010439781,0.000037911093,0.00004949564,0.00007669668,0.00011087604],"category_scores_gemma":[0.00009891564,0.00004384379,0.000045111767,0.00004154273,0.00013273775,0.0000036414888,0.000027365486,0.00009466481,6.839946e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011522944,0.0000018869409,0.00035366346,0.000031401723,0.0000241912,0.0000010282318,0.000021675052,0.0000033393144,0.969478,0.02887465,0.00069716934,0.0005014725],"study_design_scores_gemma":[0.00013157638,0.00014517344,0.002674302,0.000049624694,0.000035362835,0.000047933656,0.00019387645,0.00039105833,0.90933216,0.06609362,0.020731978,0.00017332849],"about_ca_topic_score_codex":0.000002207379,"about_ca_topic_score_gemma":0.000005569171,"teacher_disagreement_score":0.060145836,"about_ca_system_score_codex":0.0000043778514,"about_ca_system_score_gemma":0.00003564296,"threshold_uncertainty_score":0.17878978},"labels":[],"label_agreement":null},{"id":"W4396645874","doi":"10.1101/2024.05.01.592054","title":"Computational modelling of specific serotonin reuptake inhibitor inhibition on the TREK-2 channel","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Trinity College","funders":"","keywords":"Serotonin reuptake inhibitor; Serotonin; Serotonin Uptake Inhibitors; Pharmacology; Chemistry; Medicine; Fluoxetine; Biochemistry","score_opus":0.023601771509744462,"score_gpt":0.21271593590622587,"score_spread":0.1891141643964814,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396645874","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9707703,0.0016957683,0.024984565,0.00027655272,0.0011344266,0.0007305,0.00031013342,0.00007190455,0.000025853697],"genre_scores_gemma":[0.9951304,0.00030082322,0.0031013212,0.00014483706,0.0010482275,0.00013102667,0.0000056741037,0.000124291,0.000013374288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99767363,0.00012516105,0.0005571354,0.0008971207,0.00041102976,0.00033589886],"domain_scores_gemma":[0.9984288,0.00003622671,0.00032238784,0.0007475325,0.0003548211,0.000110182795],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005816339,0.00045672155,0.00036362605,0.0001627683,0.00013562942,0.000131104,0.00030714,0.00053762714,0.000048406902],"category_scores_gemma":[0.00003654068,0.00039403807,0.00026523115,0.00022813898,0.00009689867,0.000005060503,0.0004316052,0.00063426903,0.000038236478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006100443,0.00008268758,0.000009786354,0.0001931314,0.00011905836,0.000009225166,0.000013846575,0.0703214,0.9239357,0.004419973,0.00083250745,0.0000016438601],"study_design_scores_gemma":[0.00022982719,0.00013052128,0.000060759474,0.0006380961,0.000040847754,2.8549488e-8,0.0000082171355,0.01524672,0.98115236,0.00015489287,0.0019014358,0.00043631395],"about_ca_topic_score_codex":0.000009149008,"about_ca_topic_score_gemma":4.9213935e-7,"teacher_disagreement_score":0.057216607,"about_ca_system_score_codex":0.000058575482,"about_ca_system_score_gemma":0.00028637337,"threshold_uncertainty_score":0.99985117},"labels":[],"label_agreement":null},{"id":"W4396849754","doi":"10.1124/jpet.368.968610","title":"A new signalling metabolite? Characterizing N-Lactotyl-phenylalanine (Lac-Phe) activation of G protein-coupled receptors (GPCRs)","year":2024,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Allison University","funders":"","keywords":"Phenylalanine; G protein-coupled receptor; Receptor; Metabolite; Chemistry; Biochemistry; Amino acid","score_opus":0.0180543965866187,"score_gpt":0.30644252209949613,"score_spread":0.2883881255128774,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396849754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738857,0.016168553,0.008524991,0.00029132538,0.0009236696,0.00016701475,0.0000026934185,0.0000083432815,0.000027721382],"genre_scores_gemma":[0.9951909,0.0008198814,0.0024736167,0.00037185356,0.00087691314,0.0000052337687,0.000010256579,0.000028674502,0.0002226794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989679,0.00008478,0.00043904412,0.00017746438,0.00014993081,0.00018088658],"domain_scores_gemma":[0.99950284,0.000023958519,0.00025732434,0.000054128348,0.000077581324,0.00008418221],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030652736,0.00017632496,0.0002683842,0.00009926546,0.00005964091,0.000033571334,0.00012439948,0.00014804635,0.0003593265],"category_scores_gemma":[0.0000047406334,0.0001478926,0.00013644257,0.00009376109,0.0000466235,0.000030213749,0.000044732737,0.00020994966,0.0000012173148],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006039014,0.00008307413,0.000018720813,0.00003218271,0.00048617294,0.000005039287,0.0005369912,0.000026685611,0.99456435,0.00017506385,0.00010611956,0.0033616652],"study_design_scores_gemma":[0.0008742724,0.000801487,0.000009232675,0.0000578887,0.00010541607,0.0000442298,0.00027748276,0.0006135881,0.9786233,0.000087518914,0.01836408,0.00014151321],"about_ca_topic_score_codex":0.0000047493463,"about_ca_topic_score_gemma":1.035941e-7,"teacher_disagreement_score":0.021305202,"about_ca_system_score_codex":0.000026011003,"about_ca_system_score_gemma":0.00013729412,"threshold_uncertainty_score":0.6030885},"labels":[],"label_agreement":null},{"id":"W4396865566","doi":"10.1101/2024.05.10.593308","title":"A single dose of cocaine rewires the 3D genome structure of midbrain dopamine neurons","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Midbrain; Dopamine; Neuroscience; Biology; Central nervous system","score_opus":0.009715887080385843,"score_gpt":0.20884819389464382,"score_spread":0.19913230681425798,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396865566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914416,0.0058284667,0.0005106723,0.00013209123,0.0007321306,0.0004751782,0.0008318296,0.00003864642,0.000009398123],"genre_scores_gemma":[0.9965723,0.00023693984,0.0024107643,0.00009474849,0.0005287701,0.00002075053,0.0000035560704,0.00011499268,0.000017185652],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997882,0.00014224832,0.00059482385,0.00074770226,0.0002898181,0.00034341993],"domain_scores_gemma":[0.9978426,0.000032592947,0.00044239283,0.0012325372,0.00034299388,0.00010686895],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000311927,0.00044014104,0.00050525577,0.00013021215,0.000068644746,0.00006398708,0.0006474224,0.00048749393,0.000066363726],"category_scores_gemma":[0.00018918331,0.00035346585,0.00023548352,0.0002729874,0.00019269105,0.000003628056,0.0009348646,0.00049182924,0.0000028387014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047279467,0.000068694,0.00009333131,0.00049675116,0.00021876284,0.000011835947,0.0000121046405,0.00020255185,0.9984204,0.00033367611,0.0000905113,0.0000041136614],"study_design_scores_gemma":[0.00023387122,0.00020680952,0.0014087809,0.00019816884,0.00013389309,7.9204135e-8,0.000005284484,0.00011899993,0.99274033,0.000012761172,0.0045949044,0.0003461272],"about_ca_topic_score_codex":0.000033268272,"about_ca_topic_score_gemma":0.0000071206637,"teacher_disagreement_score":0.005680068,"about_ca_system_score_codex":0.000029552282,"about_ca_system_score_gemma":0.00035728453,"threshold_uncertainty_score":0.99989176},"labels":[],"label_agreement":null},{"id":"W4396978743","doi":"10.7554/elife.95694","title":"Comment on 'Accumbens cholinergic interneurons dynamically promote dopamine release and enable motivation'","year":2024,"lang":"en","type":"letter","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Mental Health; Irma T. Hirschl Trust; York University; Howard Hughes Medical Institute; National Institutes of Health; National Science Foundation","keywords":"Optogenetics; Dopamine; Neuroscience; Cholinergic; Acetylcholine; Nucleus accumbens; Striatum; Nicotinic agonist; Cholinergic neuron; Chemistry; Stimulation; Neurotransmitter; Biology; Endocrinology; Receptor; Central nervous system; Biochemistry","score_opus":0.012543771362844331,"score_gpt":0.23823695290879363,"score_spread":0.2256931815459493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396978743","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20658652,0.0011856656,0.0011405153,0.7867162,0.0015028531,0.00073834724,0.00026536718,0.00009644063,0.0017680905],"genre_scores_gemma":[0.104566164,0.0006036514,0.00059558,0.8744522,0.004814251,0.000076677265,0.002684224,0.0001679823,0.012039299],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99849135,0.000063710955,0.0002780472,0.0006273533,0.00024784068,0.00029168164],"domain_scores_gemma":[0.99935937,0.000022718243,0.00009378743,0.00037821173,0.00006578799,0.00008009593],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00012798622,0.00031885164,0.00023728712,0.00007677946,0.00005969308,0.000093039394,0.00019177311,0.00046459198,0.00009549482],"category_scores_gemma":[0.00009367551,0.00027730616,0.00011461028,0.000053983134,0.00003683653,0.0000024078613,0.00019646008,0.0007420074,0.000047370217],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023583103,0.000036039735,0.000008677802,0.000117205396,0.00008811764,0.00010323538,0.000017448885,0.000042575393,0.057602543,0.00009497019,0.9414524,0.00041322192],"study_design_scores_gemma":[0.00022797952,0.0003796184,0.000004901373,0.00013778594,0.000037394435,0.000019566061,0.000004854773,0.0005644766,0.05930862,0.00006646412,0.9389642,0.00028415694],"about_ca_topic_score_codex":0.000018061914,"about_ca_topic_score_gemma":0.0000028009138,"teacher_disagreement_score":0.10202036,"about_ca_system_score_codex":0.000029201597,"about_ca_system_score_gemma":0.000044107994,"threshold_uncertainty_score":0.99996793},"labels":[],"label_agreement":null},{"id":"W4396991704","doi":"10.1681/asn.20213210s1398d","title":"Interaction/Modulation of PKD2 by TACAN","year":2021,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Modulation (music); Medicine; Physics","score_opus":0.009291074616607036,"score_gpt":0.2605143018104976,"score_spread":0.25122322719389056,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396991704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926031,0.00031187563,0.0055881734,0.0012913335,0.00013217791,0.000022556853,0.0000055985306,6.8257384e-7,0.000044461358],"genre_scores_gemma":[0.99394995,0.00042371103,0.0036857584,0.0016655433,0.00016749083,4.005503e-7,0.000004273036,0.0000072510284,0.00009563274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931616,0.00010429127,0.00029783914,0.00008018093,0.00011524074,0.00008627691],"domain_scores_gemma":[0.99869084,0.00002241646,0.0008832225,0.00014274962,0.00023421374,0.00002654922],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017162357,0.00006143932,0.00021901635,0.000010165927,0.000029202434,0.0000030608346,0.00015198126,0.00005257164,0.00004820863],"category_scores_gemma":[0.000032254255,0.00004623038,0.0003496553,0.00010107653,0.00016490793,0.0000040009295,0.000061730985,0.00011240452,1.8363757e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060306338,0.000041764157,0.00054452935,0.000005531966,0.00015908851,2.4727922e-7,0.000080280755,0.00026207932,0.97380507,0.000011661489,0.023056764,0.0019726732],"study_design_scores_gemma":[0.0002905254,0.0005100326,0.0042144256,0.000011913829,0.000036619556,0.00008938082,0.0009749212,0.00013707379,0.93338287,0.00012579092,0.06017029,0.000056171473],"about_ca_topic_score_codex":0.000022128435,"about_ca_topic_score_gemma":0.0000026117264,"teacher_disagreement_score":0.04042222,"about_ca_system_score_codex":0.000011980118,"about_ca_system_score_gemma":0.00010152729,"threshold_uncertainty_score":0.18852201},"labels":[],"label_agreement":null},{"id":"W4398510884","doi":"10.7910/dvn/1pc3lo/v9d5lu","title":"GBFE-PGDP.RAT","year":2019,"lang":"en","type":"dataset","venue":"Harvard Dataverse","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"HEC Montréal","funders":"","keywords":"Computer science","score_opus":0.013713468243092247,"score_gpt":0.2412713538137566,"score_spread":0.22755788557066436,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398510884","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00019724763,0.000012566369,0.00022621904,0.0000026166335,0.001856423,0.00025771916,0.99726385,0.000010953467,0.00017239366],"genre_scores_gemma":[0.0000451634,0.0009148847,0.00031145354,0.0005586882,0.00085060083,0.000018597368,0.99465567,0.00004033722,0.0026046014],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998312,0.00007111376,0.00027857654,0.00070766255,0.0002601191,0.00037050882],"domain_scores_gemma":[0.9979537,0.000011029092,0.00017521948,0.0016601726,0.000068630456,0.00013124112],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00021291102,0.0003707816,0.00032742906,0.000075342374,0.00007894124,0.00008322913,0.0007276535,0.00060225074,0.024772424],"category_scores_gemma":[0.000091900125,0.0003572027,0.00019432756,0.00006160581,0.00004443885,0.000006442245,0.0005465766,0.000275001,0.07398625],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048006532,0.00003652166,0.0000015163786,0.0000719011,0.000079752244,0.000017881739,0.0000021549677,0.000014503473,0.04770207,0.000007632374,0.9519039,0.00011418972],"study_design_scores_gemma":[0.0003678776,0.00016121277,7.703889e-7,0.00004304168,0.00007720459,0.000017384651,0.000020719912,0.000006970068,0.020993482,0.000007422948,0.9778667,0.00043720356],"about_ca_topic_score_codex":0.00005698837,"about_ca_topic_score_gemma":0.00003275117,"teacher_disagreement_score":0.049213823,"about_ca_system_score_codex":0.000021707057,"about_ca_system_score_gemma":0.00014969661,"threshold_uncertainty_score":0.999888},"labels":[],"label_agreement":null},{"id":"W4399053704","doi":"10.3390/ijms25115779","title":"Structural Features Influencing the Bioactive Conformation of Angiotensin II and Angiotensin A: Relationship between Receptor Desensitization, Addiction, and the Blood–Brain Barrier","year":2024,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Victoria University","keywords":"Angiotensin II; Tachyphylaxis; Chemistry; Inverse agonist; Receptor; Agonist; Sarcosine; Losartan; Desensitization (medicine); Pharmacology; Peptide; Biophysics; Antagonist; Biochemistry; Internal medicine; Endocrinology; Amino acid; Glycine; Biology; Medicine","score_opus":0.009611225211985427,"score_gpt":0.25696760869931223,"score_spread":0.2473563834873268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399053704","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98742384,0.004323417,0.0032419642,0.004611583,0.0002814493,0.00007377181,0.000013369697,0.0000027528224,0.000027845612],"genre_scores_gemma":[0.9980683,0.00010719631,0.0013417171,0.00024536642,0.00019965258,6.6656406e-7,0.000009239478,0.000004701849,0.000023194418],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991045,0.00011635944,0.00026599437,0.00011255836,0.0003269849,0.00007360897],"domain_scores_gemma":[0.9991674,0.00015935773,0.00019674073,0.000055316847,0.00038939225,0.000031790587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00086092716,0.00007795383,0.000094272364,0.0001086447,0.0002051558,0.00010965803,0.00016600416,0.00005865807,0.0000053717404],"category_scores_gemma":[0.0004389773,0.000043753447,0.000070819435,0.00013109336,0.00041465857,0.00004344705,0.00006928437,0.00011078046,1.3769632e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013082828,0.000006125872,0.0057723117,0.0000065920262,0.0005839642,0.000008074762,0.0034012084,0.0012508428,0.9594668,0.02019392,0.0010867579,0.008092567],"study_design_scores_gemma":[0.0014881225,0.0005593786,0.046527416,0.00030190454,0.00026072637,0.00089197163,0.0020474694,0.0026674028,0.93296987,0.008866042,0.003139215,0.00028047536],"about_ca_topic_score_codex":0.00001971669,"about_ca_topic_score_gemma":0.000003001986,"teacher_disagreement_score":0.040755104,"about_ca_system_score_codex":0.0000083346085,"about_ca_system_score_gemma":0.00009106637,"threshold_uncertainty_score":0.17842138},"labels":[],"label_agreement":null},{"id":"W4399128816","doi":"10.1038/s41467-024-48196-2","title":"G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Agencia Estatal de Investigación; Instituto de Salud Carlos III; Canadian Institutes of Health Research; Ministerio de Ciencia e Innovación; European Regional Development Fund; Deutsche Forschungsgemeinschaft; Eusko Jaurlaritza; Bundesministerium für Bildung und Forschung; Xunta de Galicia; European Commission","keywords":"G protein-coupled receptor; Neuroscience; Psychosis; Schizophrenia (object-oriented programming); Receptor; Agonist; 5-HT receptor; Serotonin; Signal transduction; Endogenous agonist; Functional selectivity; Stimulation; Biology; Pharmacology; Cell biology; Psychology; Biochemistry; Psychiatry","score_opus":0.009324325043515146,"score_gpt":0.26139003897273505,"score_spread":0.2520657139292199,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399128816","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8269242,0.15845983,0.0016101433,0.0065803444,0.0007375967,0.0024205425,0.000032337593,0.000111294976,0.0031237102],"genre_scores_gemma":[0.98992884,0.0025358594,0.0063150343,0.00026804663,0.00004847041,0.00031382192,0.00018536339,0.000031118943,0.00037341603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988427,0.00030628356,0.0002100843,0.00032251424,0.00013512453,0.00018326209],"domain_scores_gemma":[0.99866974,0.00008340796,0.000045415683,0.0011112544,0.000049749622,0.000040458086],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056834205,0.00016270121,0.00012309675,0.000078450365,0.00019811917,0.00010092675,0.00068410207,0.00043232375,0.000031943495],"category_scores_gemma":[0.00004259013,0.00012264968,0.000065676744,0.0002976805,0.00007238017,0.000008419267,0.00017969776,0.0007549548,0.000019362846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001287835,0.000048737907,0.000009756205,0.00003364105,0.00003527902,0.0000015721315,0.0003030053,0.0000060054967,0.94515055,0.046596594,0.001917025,0.0058849757],"study_design_scores_gemma":[0.0006820208,0.0003047428,0.00054184295,0.00045242332,0.000040881267,0.00005025584,0.00045198787,0.0006983172,0.6563109,0.0079476,0.33200437,0.0005146448],"about_ca_topic_score_codex":0.000007635882,"about_ca_topic_score_gemma":0.000051142484,"teacher_disagreement_score":0.33008733,"about_ca_system_score_codex":0.00001693154,"about_ca_system_score_gemma":0.000026717596,"threshold_uncertainty_score":0.50015086},"labels":[],"label_agreement":null},{"id":"W4399324177","doi":"10.1126/scisignal.ade8041","title":"Growth factor–dependent phosphorylation of Gα <sub>i</sub> shapes canonical signaling by G protein–coupled receptors","year":2024,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, San Diego; National Cancer Institute; National Institutes of Health; Université de Montréal; National Institute of Allergy and Infectious Diseases; Augusta University; National Institute of General Medical Sciences; University of South Carolina; American Association of Immunologists","keywords":"G protein-coupled receptor; Phosphorylation; Signal transduction; Tyrosine phosphorylation; G protein; Biology; Cell biology; Protein phosphorylation; Receptor; Biochemistry; Chemistry; Protein kinase A","score_opus":0.008897355700794574,"score_gpt":0.23638411050797636,"score_spread":0.22748675480718178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399324177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.984517,0.0016638725,0.012915121,0.00004298827,0.00038177168,0.00034467672,0.000015502936,0.0000343298,0.000084774336],"genre_scores_gemma":[0.99885195,0.000076936776,0.00076693116,0.000029844858,0.00013851443,0.00003229629,0.000024266252,0.00003312416,0.000046137815],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974185,0.000065535816,0.00051962194,0.00080710737,0.00066400133,0.00052520307],"domain_scores_gemma":[0.99931663,0.000039242852,0.00012755964,0.00017970259,0.00018719322,0.00014964983],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012906161,0.00024252973,0.00024434229,0.00021421845,0.00017048328,0.0001541316,0.00042033347,0.00017895296,0.00013821425],"category_scores_gemma":[0.00020922083,0.00022686942,0.0001293555,0.0007079269,0.00022468143,0.000047068555,0.00012411032,0.00022383174,0.0000093257795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029351255,0.00003273578,0.00015830234,0.00005467987,0.00001568458,0.000004092397,0.00018135144,0.0010799015,0.99603444,0.00028908468,0.000017530378,0.0021028642],"study_design_scores_gemma":[0.0001937053,0.00017927929,0.000026443246,0.000214506,0.000009852133,0.000003691337,0.00017634101,0.0051000686,0.9933578,0.00038301575,0.00007904236,0.00027626613],"about_ca_topic_score_codex":0.00008027818,"about_ca_topic_score_gemma":0.000013850596,"teacher_disagreement_score":0.014334986,"about_ca_system_score_codex":0.00009843328,"about_ca_system_score_gemma":0.00050608645,"threshold_uncertainty_score":0.92514664},"labels":[],"label_agreement":null},{"id":"W4399642399","doi":"10.1038/s42255-024-01061-4","title":"Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes","year":2024,"lang":"en","type":"article","venue":"Nature Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Diabetesforeningen; Svenska Läkaresällskapet; Sundhedsstyrelsen; Novo Nordisk Fonden; Svenska Sällskapet för Medicinsk Forskning; Université de Montréal; Vetenskapsrådet; Lundbeckfonden; H. Lundbeck A/S; Stiftelsen för Strategisk Forskning; Eli Lilly and Company; European Foundation for the Study of Diabetes; Augusta University; Robert Bosch Stiftung; McGill University; Novo Nordisk Foundation Center for Basic Metabolic Research; Novo Nordisk; European Federation of Pharmaceutical Industries and Associations","keywords":"Phenotype; Biology; Genetics; Evolutionary biology; Computational biology; Gene","score_opus":0.004458533803256562,"score_gpt":0.2417431001062858,"score_spread":0.23728456630302924,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399642399","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9613157,0.017754247,0.019687096,0.00004747814,0.00072818995,0.000247284,0.0001691018,0.000008546848,0.000042366173],"genre_scores_gemma":[0.9958983,0.00044999027,0.003007272,0.00007035706,0.00031330204,0.000011242966,0.00013266377,0.00002004911,0.00009683017],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989275,0.00008232155,0.00039373746,0.00025261706,0.00019764625,0.00014621465],"domain_scores_gemma":[0.9992567,0.000014294361,0.00015842225,0.00022795876,0.0002907899,0.000051868017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030861967,0.00013180112,0.0003486864,0.00012214818,0.000016640635,0.000009552187,0.00015199308,0.00028640914,0.00006110304],"category_scores_gemma":[0.00022210897,0.00011402142,0.000119744116,0.00029685206,0.000025644154,0.0000059333206,0.00005227362,0.00012033221,0.000002258313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060207196,0.000028754825,0.00011327117,0.00006463124,0.00009392475,6.663016e-7,0.00007348718,0.00002454663,0.98730147,0.007866979,0.00004451706,0.0043275435],"study_design_scores_gemma":[0.00020043613,0.00006108806,0.026231071,0.000073869254,0.0001076572,0.0000026448115,0.000005047511,0.00005989215,0.9596021,0.0004283667,0.01312709,0.00010069955],"about_ca_topic_score_codex":0.000010801968,"about_ca_topic_score_gemma":0.0000018518724,"teacher_disagreement_score":0.034582604,"about_ca_system_score_codex":0.0000029630833,"about_ca_system_score_gemma":0.00006241841,"threshold_uncertainty_score":0.46496588},"labels":[],"label_agreement":null},{"id":"W4399767133","doi":"10.1126/scisignal.adi4747","title":"Conformation- and activation-based BRET sensors differentially report on GPCR–G protein coupling","year":2024,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"G protein-coupled receptor; Heterotrimeric G protein; Receptor; G protein; Cell biology; Förster resonance energy transfer; Functional selectivity; Chemistry; Biophysics; Signal transduction; Biology; Biochemistry","score_opus":0.010316488265952042,"score_gpt":0.2543559810697836,"score_spread":0.24403949280383153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399767133","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9396438,0.000068432775,0.05947896,0.000118750264,0.00020076049,0.00019976098,0.0000034775173,0.000036284764,0.00024976945],"genre_scores_gemma":[0.9981434,0.0000037941586,0.0013960369,0.00008819464,0.00014476986,0.000015737663,0.000032648164,0.000013553834,0.00016190356],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987725,0.000012081528,0.00022127698,0.00042297962,0.00034117844,0.00022996798],"domain_scores_gemma":[0.9995142,0.000023290408,0.00008948693,0.00017775262,0.00010879116,0.000086479886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007510729,0.00012735212,0.00009098763,0.00012562869,0.00028469655,0.00021711162,0.00012861715,0.000069639245,0.00005817326],"category_scores_gemma":[0.00017134397,0.00010963745,0.000044337074,0.00022095357,0.00013382465,0.000021812031,0.000037639864,0.00010165385,0.0000057763964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000119860315,0.0000072593275,0.000034824832,0.000027809283,0.0000067786345,0.0000064089063,0.00005106382,0.0062081744,0.9919321,0.001216837,0.000014178542,0.00048259785],"study_design_scores_gemma":[0.00010335902,0.000100404046,0.000029815104,0.00015752297,0.0000050518224,0.000010412688,0.00007429876,0.056009132,0.9426877,0.000316373,0.00036029003,0.0001456478],"about_ca_topic_score_codex":0.000008623643,"about_ca_topic_score_gemma":6.35189e-7,"teacher_disagreement_score":0.05849956,"about_ca_system_score_codex":0.000023206154,"about_ca_system_score_gemma":0.00027731943,"threshold_uncertainty_score":0.44708854},"labels":[],"label_agreement":null},{"id":"W4399933042","doi":"10.34172/jnp.2024.22542","title":"Zilebesiran for treating hypertension; the result of recent findings","year":2024,"lang":"en","type":"article","venue":"Journal of Nephropathology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Université de Montréal","funders":"","keywords":"Medicine; Dosing; Blood pressure; Adverse effect; Concomitant; Food and drug administration; Clinical trial; Pharmacology; Intensive care medicine; Internal medicine","score_opus":0.025836223283550643,"score_gpt":0.280920772396892,"score_spread":0.2550845491133414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399933042","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841562,0.003777106,0.010098034,0.0009126421,0.00077376165,0.00010660427,0.000010091855,0.0000034697568,0.00016209472],"genre_scores_gemma":[0.9933934,0.0011487996,0.00431653,0.00035603638,0.0006064333,0.000003624054,0.0000063093594,0.000018934774,0.00014992438],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991814,0.000073263436,0.00038738936,0.00012450374,0.00009502588,0.00013842188],"domain_scores_gemma":[0.9993979,0.00008089535,0.00014602882,0.00012281482,0.00021948814,0.000032869957],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00071962236,0.00008636925,0.00019044899,0.00006008645,0.00006006276,0.000016226444,0.00014877447,0.00008984657,0.00004428971],"category_scores_gemma":[0.00025841384,0.000051760268,0.00017508016,0.00007642833,0.000056399156,0.0000040601026,0.00003225303,0.00011349247,0.000001037031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014831153,0.000020338844,0.000021078802,0.000020856487,0.000043856504,0.00002984214,0.00012724922,0.00004494848,0.98428786,0.00029570746,0.0042240717,0.01073589],"study_design_scores_gemma":[0.000605244,0.0016700975,0.00028214746,0.00008422646,0.00009864755,0.001454285,0.00035148062,0.00026591634,0.8328876,0.00082216074,0.16137299,0.000105227205],"about_ca_topic_score_codex":0.0000013706533,"about_ca_topic_score_gemma":8.504314e-7,"teacher_disagreement_score":0.15714891,"about_ca_system_score_codex":0.000009428199,"about_ca_system_score_gemma":0.00007642858,"threshold_uncertainty_score":0.21107225},"labels":[],"label_agreement":null},{"id":"W4400011975","doi":"10.26434/chemrxiv-2023-mbr7t-v3","title":"A mechanistic model explaining ligand affinity for, and partial agonism of, cannabinoid receptor 1","year":2024,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; University of Windsor","keywords":"Agonism; Cannabinoid; Ligand (biochemistry); Chemistry; Cannabinoid receptor; Receptor; Biochemistry; Antagonist; Political science","score_opus":0.023164772064859087,"score_gpt":0.26453507270922855,"score_spread":0.24137030064436946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400011975","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9459092,0.0027635943,0.049445525,0.00011193852,0.0008524276,0.00047644053,0.00011788167,0.000032204054,0.0002907864],"genre_scores_gemma":[0.9875428,0.0004028017,0.0103142075,0.000055995675,0.00050122367,0.00022343914,0.00030492956,0.000072930874,0.0005816838],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984707,0.000022824986,0.00036146014,0.000721187,0.00012920366,0.0002945774],"domain_scores_gemma":[0.99918884,0.000016464437,0.00017378219,0.00037654035,0.000119806085,0.00012456924],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033962488,0.00032827587,0.0003941104,0.00005679986,0.000078475045,0.00006357917,0.0002174105,0.00055675226,0.000018089298],"category_scores_gemma":[0.00012325532,0.00032854764,0.00021782373,0.000038360693,0.00006850419,0.0000017913352,0.00074375415,0.00029368058,0.0000022993645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000082548475,0.0000265167,0.0000030973513,0.00063855865,0.00011380388,0.0000011143418,0.00024293976,0.00058235053,0.9932269,0.003377888,0.0011673674,0.0005369148],"study_design_scores_gemma":[0.0002807017,0.00013780607,4.87918e-7,0.00017173935,0.000110790046,0.0000029557832,0.000059713126,0.015064392,0.9633765,0.019152924,0.001293288,0.00034866587],"about_ca_topic_score_codex":0.000016800546,"about_ca_topic_score_gemma":0.0000046809078,"teacher_disagreement_score":0.041633587,"about_ca_system_score_codex":0.000018709217,"about_ca_system_score_gemma":0.00026816913,"threshold_uncertainty_score":0.9999167},"labels":[],"label_agreement":null},{"id":"W4400026073","doi":"10.17615/66k5-6h03","title":"Allostery of atypical modulators at oligomeric G protein-coupled receptors","year":2024,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Allosteric regulation; Receptor; Chemistry; Biophysics; Biochemistry; Computational biology; Cell biology; Biology","score_opus":0.008086611378661887,"score_gpt":0.20927017989650243,"score_spread":0.20118356851784053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400026073","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922761,0.0034300578,0.0027833139,0.00012227645,0.0005897878,0.00019436216,0.0000094822535,0.00005061203,0.00054403266],"genre_scores_gemma":[0.9889614,0.000028428221,0.0058150333,0.00006934771,0.00030779192,0.000025487247,0.00009393026,0.000040613704,0.0046579824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999067,0.000033532353,0.00023360351,0.00031726056,0.00014509755,0.00020348009],"domain_scores_gemma":[0.9996121,0.000014645617,0.000044802953,0.00022952018,0.000025846422,0.00007311871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000871684,0.00015702443,0.0001738585,0.00005767833,0.000056917088,0.000058670743,0.00015272651,0.00016247923,0.0006466685],"category_scores_gemma":[0.00003592304,0.0001310847,0.0001351301,0.00014001342,0.0001029925,0.000014806317,0.00017822803,0.000073576775,0.000029828117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013117927,0.000019298077,0.0002546481,0.000086211105,0.00008131977,0.0000036744611,0.00011467816,0.00002957269,0.97163916,0.024807632,0.0018530881,0.0009795614],"study_design_scores_gemma":[0.00012772199,0.00020933199,0.000051288305,0.000057680252,0.000013472829,0.0000051908646,0.000050442017,0.00036135188,0.9591382,0.005343345,0.034471482,0.00017049981],"about_ca_topic_score_codex":0.000007401608,"about_ca_topic_score_gemma":0.000002200214,"teacher_disagreement_score":0.032618396,"about_ca_system_score_codex":0.000010831304,"about_ca_system_score_gemma":0.00008449038,"threshold_uncertainty_score":0.7080566},"labels":[],"label_agreement":null},{"id":"W4400190320","doi":"10.1021/acs.jmedchem.4c00665","title":"Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for <i>In Vivo</i> Mouse Studies","year":2024,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Chemistry; Penetrant (biochemical); Allosteric regulation; Pharmacology; In vivo; Agonist; Receptor; Orphan receptor; Biochemistry; Genetics; Medicine; Gene; Biology","score_opus":0.015826209052560176,"score_gpt":0.29031762411401896,"score_spread":0.2744914150614588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400190320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9787563,0.016228452,0.0035029945,0.00060486555,0.000566032,0.00012056278,0.00006694299,0.000004841372,0.0001490008],"genre_scores_gemma":[0.9945021,0.0014613996,0.0010185901,0.00016720826,0.0012104291,0.000008846244,0.000020800202,0.000032080927,0.0015785065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843264,0.000028594737,0.0007310209,0.00024252171,0.00032286035,0.00024234637],"domain_scores_gemma":[0.99915314,0.00014550699,0.00026423755,0.00016470677,0.00019832289,0.000074084724],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00083448144,0.00020712473,0.0004638426,0.00005794103,0.00004179136,0.00003994398,0.00024873886,0.00014833845,0.000052453404],"category_scores_gemma":[0.00028003388,0.00016082039,0.000295603,0.000103955404,0.00012980052,0.000016930708,0.00005030154,0.00023943,5.182602e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000370488,0.00007640739,0.00004658433,0.0008008015,0.0002640698,0.00004050535,0.00014787598,0.000050288436,0.9854157,0.00003935927,0.012220709,0.00052719534],"study_design_scores_gemma":[0.0010206666,0.00048015782,0.0000033077324,0.00065060664,0.0000705587,0.00018590855,0.0010253428,0.000047015285,0.9741975,0.00014363846,0.022007547,0.0001677589],"about_ca_topic_score_codex":0.000005056592,"about_ca_topic_score_gemma":0.0000033772062,"teacher_disagreement_score":0.015745832,"about_ca_system_score_codex":0.000058377125,"about_ca_system_score_gemma":0.00026870702,"threshold_uncertainty_score":0.65580654},"labels":[],"label_agreement":null},{"id":"W4400233237","doi":"10.1126/scisignal.abq7038","title":"Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling","year":2024,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Japan Society for the Promotion of Science; Japan Science and Technology Agency; Biotechnology and Biological Sciences Research Council; Medical Research Council; Breakthrough T1D Canada; Japan Agency for Medical Research and Development","keywords":"G protein-coupled receptor; Internalization; Endosome; Endocytic cycle; Cell biology; Intracellular; G protein; Signal transduction; Biology; Receptor; Arrestin; Phosphorylation; Cell signaling; Endocytosis; Biochemistry","score_opus":0.0066046718563671164,"score_gpt":0.23221514601529708,"score_spread":0.22561047415892996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400233237","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91926473,0.0025951099,0.07739849,0.000070452224,0.0002952777,0.00024754915,0.000008708733,0.000023393088,0.000096289215],"genre_scores_gemma":[0.99799514,0.00006646359,0.0015895445,0.0000338105,0.00017954002,0.000015911259,0.000010897397,0.0000196254,0.000089082125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859864,0.00004285203,0.00029614364,0.00044642974,0.0003300432,0.0002859046],"domain_scores_gemma":[0.9994574,0.00003357953,0.00008112612,0.00021097886,0.00013117542,0.00008572296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010733824,0.00016209688,0.00013583202,0.00011934867,0.00019534667,0.00018625047,0.00032472712,0.00007780496,0.000041060295],"category_scores_gemma":[0.00012732334,0.00011579896,0.00007317813,0.00042756784,0.00032638796,0.000022653276,0.00012948764,0.00012287138,0.0000024663018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001111277,0.000011180148,0.000056653527,0.000051206443,0.00002455473,0.000003642435,0.00045390858,0.0027807436,0.9922703,0.00088568404,0.000008822463,0.0034421966],"study_design_scores_gemma":[0.00010634571,0.00013529422,0.000007808149,0.00019817128,0.000025723019,0.000022372124,0.0003581829,0.017030386,0.98097426,0.0004498103,0.0005410973,0.00015052824],"about_ca_topic_score_codex":0.000019019959,"about_ca_topic_score_gemma":0.0000022232102,"teacher_disagreement_score":0.07873039,"about_ca_system_score_codex":0.00001572484,"about_ca_system_score_gemma":0.00013885276,"threshold_uncertainty_score":0.47221446},"labels":[],"label_agreement":null},{"id":"W4400378486","doi":"10.1101/2024.07.03.601861","title":"Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Lundbeckfonden; NYU Grossman School of Medicine; H. Lundbeck A/S; York University","keywords":"Striatum; Neuroscience; Tonic (physiology); Dopamine; Basal ganglia; Extracellular; Biology; Psychology; Cell biology; Central nervous system","score_opus":0.015875063517511206,"score_gpt":0.22672203975744637,"score_spread":0.21084697623993517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400378486","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9753494,0.003460593,0.01953905,0.000054074913,0.00094868895,0.00039770102,0.00021677595,0.000027353142,0.000006311085],"genre_scores_gemma":[0.99536765,0.0006530272,0.003467614,0.000030524356,0.00034232173,0.000051748222,0.0000056155836,0.00007465488,0.00000685073],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99785817,0.00013063534,0.0006203125,0.00072016823,0.0003531318,0.00031758507],"domain_scores_gemma":[0.99865556,0.000038471997,0.00029927367,0.00068135164,0.00026337808,0.000061994026],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006805442,0.00036663172,0.00038729,0.00018910038,0.000074681586,0.00016044852,0.0005863402,0.00042706224,0.000009857816],"category_scores_gemma":[0.000030837895,0.00032775156,0.00019293826,0.00025951825,0.00009242477,0.000006649285,0.0004443216,0.00048087476,0.000007637002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000107406515,0.00024211376,0.003190743,0.0009770155,0.00019896885,0.00009541964,0.00005919453,0.07120335,0.91655356,0.007001909,0.00035747763,0.000012813749],"study_design_scores_gemma":[0.0007179574,0.00014825848,0.0025461768,0.0010932614,0.000120842626,2.1215808e-7,0.00008604483,0.22208147,0.770544,0.00033278888,0.0011922924,0.0011367071],"about_ca_topic_score_codex":0.00004799657,"about_ca_topic_score_gemma":0.000017475924,"teacher_disagreement_score":0.15087812,"about_ca_system_score_codex":0.00007541781,"about_ca_system_score_gemma":0.00027124365,"threshold_uncertainty_score":0.99991745},"labels":[],"label_agreement":null},{"id":"W4400397991","doi":"10.1038/s42003-024-06512-y","title":"Role of the V2R–βarrestin–Gβγ complex in promoting G protein translocation to endosomes","year":2024,"lang":"en","type":"article","venue":"Communications Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Fonds de Recherche du Québec - Santé; Government of Canada; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Howard Hughes Medical Institute","keywords":"Endosome; Heterotrimeric G protein; G protein-coupled receptor; Cell biology; Internalization; G protein-coupled receptor kinase; G protein; Arrestin; Gq alpha subunit; Signal transduction; Transport protein; Chemistry; Biology; Receptor; Biochemistry; Intracellular","score_opus":0.025038340187304997,"score_gpt":0.2983995030669378,"score_spread":0.2733611628796328,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400397991","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987997,0.0065759015,0.0015327252,0.0023190095,0.00006787773,0.0006366136,0.000021204682,0.000020168056,0.00082950934],"genre_scores_gemma":[0.9959128,0.00010771606,0.0036192532,0.00005835814,0.000024508934,0.0001408864,0.0000788322,0.000010705398,0.000046948033],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99926114,0.00019008717,0.00022570131,0.00016814504,0.000033890017,0.000121061115],"domain_scores_gemma":[0.9991537,0.000028417591,0.00004017776,0.0007165436,0.00004239908,0.000018800933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000247055,0.00007526199,0.000095916555,0.00005655924,0.000071268674,0.000011011078,0.0006173559,0.000086412656,0.000019926058],"category_scores_gemma":[0.000088390385,0.000058137302,0.00005241168,0.00022036817,0.00008751402,0.0000024270855,0.00022432714,0.000104977335,0.000005041519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004494022,0.000028411136,0.0003715003,0.000011766203,0.000010203041,3.0631398e-8,0.00032168566,0.000022502774,0.97097194,0.0069958395,0.000013585729,0.021248035],"study_design_scores_gemma":[0.00013232532,0.00013229823,0.0010144808,0.00012961814,0.0000061902206,0.000003972796,0.00022237691,0.0026800567,0.9438757,0.0034513385,0.048236992,0.00011466219],"about_ca_topic_score_codex":0.00005448749,"about_ca_topic_score_gemma":0.00012921302,"teacher_disagreement_score":0.048223406,"about_ca_system_score_codex":0.000011497395,"about_ca_system_score_gemma":0.00006370899,"threshold_uncertainty_score":0.23707703},"labels":[],"label_agreement":null},{"id":"W4400673739","doi":"10.1139/bcb-2024-0053","title":"Pathophysiological relevance and therapeutic outlook of GPR43 in atherosclerosis","year":2024,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Natural Science Foundation of Hunan Province","keywords":"G protein-coupled receptor; Inflammation; Receptor; Pathophysiology; Lipoprotein; Oxidative stress; Dyslipidemia; Apolipoprotein B; Biology; Endothelial dysfunction; Pathogenesis; Pharmacology; Bioinformatics; Biochemistry; Endocrinology; Cholesterol; Diabetes mellitus; Immunology","score_opus":0.02448773653384415,"score_gpt":0.28137676077118284,"score_spread":0.25688902423733867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400673739","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.033694956,0.9657454,0.0000142701465,0.000004532549,0.00009806971,0.0001746367,0.000076818425,0.0000076222686,0.00018368178],"genre_scores_gemma":[0.03371296,0.96536636,0.00013013085,0.000028957233,0.00013712331,0.00004637506,0.0001649507,0.00002903397,0.00038408794],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99847066,0.00010231051,0.00042538226,0.00071701064,0.000041358595,0.0002432963],"domain_scores_gemma":[0.99944127,0.00004145292,0.00016847323,0.00026490912,0.000019312427,0.000064578315],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00017855217,0.00036612805,0.00082723337,0.00003938231,0.000027641327,0.0000120532,0.00016852422,0.00092584477,0.000018769519],"category_scores_gemma":[0.000026745407,0.00026543433,0.00019581529,0.00008553938,0.0002016484,9.21901e-7,0.00020328021,0.00025162255,0.0000031189088],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013186144,0.000035876717,0.000009770026,0.004721772,0.000047613856,0.0000016622193,0.000010246623,1.1947367e-7,0.81965935,0.000050768667,0.000024874269,0.17542478],"study_design_scores_gemma":[0.0003636978,0.0005823129,0.000004106545,0.0025802217,0.0003671271,0.000027831167,0.00005312021,0.0000061644046,0.29985166,0.00050751737,0.6949107,0.0007455437],"about_ca_topic_score_codex":0.0000042743236,"about_ca_topic_score_gemma":5.778672e-7,"teacher_disagreement_score":0.69488585,"about_ca_system_score_codex":0.000010278683,"about_ca_system_score_gemma":0.000072107054,"threshold_uncertainty_score":0.9999798},"labels":[],"label_agreement":null},{"id":"W4400686815","doi":"10.1021/acsptsci.4c00330","title":"Exploring an Intracellular Allosteric Site of CC-Chemokine Receptor 4 from 3D Models, Probe Simulations, and Mutagenesis","year":2024,"lang":"en","type":"article","venue":"ACS Pharmacology & Translational Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"HORIZON EUROPE Marie Sklodowska-Curie Actions; University of Glasgow; Biotechnology and Biological Sciences Research Council; European Commission; Queen's University; Queen's University Belfast","keywords":"Allosteric regulation; In silico; Homology modeling; Molecular dynamics; Computational biology; Chemistry; Mutagenesis; CC chemokine receptors; G protein-coupled receptor; Chemokine receptor; Binding site; Biophysics; Biology; Receptor; Biochemistry; Chemokine; Mutant; Gene; Computational chemistry","score_opus":0.055725389234979404,"score_gpt":0.2920995912128945,"score_spread":0.23637420197791512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400686815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9635536,0.0019741042,0.03357733,0.00023490764,0.00034083682,0.0001667057,0.00010545171,0.000019856318,0.000027174046],"genre_scores_gemma":[0.98631394,0.00038756797,0.012719888,0.000087175824,0.00025031265,0.000021547865,0.00018485215,0.000014951935,0.000019772968],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998812,0.00004741909,0.00022891648,0.00049038895,0.00022168607,0.00019958796],"domain_scores_gemma":[0.9996136,0.00003976531,0.000043264747,0.000108294065,0.0000962279,0.000098841265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031028813,0.00012954835,0.000119845696,0.00009606135,0.00014031658,0.000038237635,0.0001678157,0.00007043195,0.00014324201],"category_scores_gemma":[0.0000073553156,0.00012613209,0.000034501107,0.00026215712,0.00021813667,0.00010407798,0.000048510272,0.00008142765,0.0000027622561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039422124,0.00008082737,0.00010611512,0.000015269727,0.000031846113,0.000001683088,0.00039403743,0.0056121806,0.9864277,0.0002882162,0.0000076764145,0.0069950214],"study_design_scores_gemma":[0.0005383468,0.00009737425,0.00015224365,0.0000137989,0.00004586812,0.0000032035268,0.000025717185,0.07111143,0.92580724,0.0005689146,0.0014911017,0.00014475276],"about_ca_topic_score_codex":0.000026764312,"about_ca_topic_score_gemma":0.0000057487996,"teacher_disagreement_score":0.06549925,"about_ca_system_score_codex":0.000011202216,"about_ca_system_score_gemma":0.00013347877,"threshold_uncertainty_score":0.5143517},"labels":[],"label_agreement":null},{"id":"W4400966813","doi":"10.1101/2024.07.22.604482","title":"The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Breast cancer; Biology; Cancer research; Matrigel; G protein-coupled receptor; Cancer cell; Cancer; Cell biology; Signal transduction; Angiogenesis; Genetics","score_opus":0.006620318467648406,"score_gpt":0.20539303738981782,"score_spread":0.1987727189221694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400966813","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891512,0.00400778,0.0030705454,0.00047499037,0.0013731716,0.0010903281,0.00073899137,0.00009164993,0.0000013619433],"genre_scores_gemma":[0.9950849,0.00066222035,0.002684883,0.00009118359,0.00094609044,0.00020973658,0.0000034924828,0.00023247574,0.000085014435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974106,0.00007501016,0.0006284324,0.0010221733,0.00040374784,0.0004600252],"domain_scores_gemma":[0.99697095,0.000015324547,0.0005183137,0.0011939161,0.0011245682,0.0001769378],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005026123,0.0005360093,0.0004303829,0.0001011159,0.00021785208,0.00020861287,0.0006534785,0.00071311556,0.00020738118],"category_scores_gemma":[0.00014510695,0.00045001926,0.00020622458,0.000459996,0.00013198062,0.0000075329904,0.0008013223,0.0004608072,0.000029218369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005620443,0.00008076837,0.00026387267,0.0003827819,0.00041449998,0.0000018532525,0.000013583445,0.00006242484,0.99792963,0.00041207683,0.00037874826,0.0000035537298],"study_design_scores_gemma":[0.00037206238,0.000045058365,0.0007712325,0.0005183431,0.00015437388,3.6442376e-8,0.0000068159193,0.00088456454,0.9925001,0.000003025163,0.004210827,0.0005335438],"about_ca_topic_score_codex":0.000108604654,"about_ca_topic_score_gemma":0.000005035238,"teacher_disagreement_score":0.005933722,"about_ca_system_score_codex":0.00009926842,"about_ca_system_score_gemma":0.0008898274,"threshold_uncertainty_score":0.99979514},"labels":[],"label_agreement":null},{"id":"W4401011037","doi":"10.1101/2024.07.26.605371","title":"Ligand induced receptor multimerization achieves the specificity enhancement of kinetic proofreading without associated costs","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Proofreading; Receptor; Ligand (biochemistry); Biophysics; Chemistry; Cell biology; Computational biology; Biology; Biochemistry; DNA; Polymerase","score_opus":0.01331919926958216,"score_gpt":0.2318128866899039,"score_spread":0.21849368742032174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401011037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939864,0.0012550148,0.0021449777,0.00008320759,0.0013444726,0.0009742919,0.00012401967,0.000068609246,0.000018988974],"genre_scores_gemma":[0.99709976,0.00032605464,0.0017337801,0.000054017404,0.00048629404,0.00013863343,0.000006659985,0.00011964957,0.00003514963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997573,0.00019470592,0.00060477527,0.0008670543,0.0003712947,0.00038916356],"domain_scores_gemma":[0.9981014,0.00002510739,0.00055047055,0.0007927001,0.0004155993,0.000114692004],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006672934,0.00047999568,0.00046478107,0.00011195078,0.00013590211,0.00015216137,0.00047669164,0.0006024903,0.000044949677],"category_scores_gemma":[0.00028414713,0.00040418978,0.0001853862,0.0002911709,0.000085219246,0.0000060906177,0.000600457,0.0005614564,0.000023808763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042460695,0.000112079215,0.0011475036,0.00017216112,0.00029068807,0.0000014677238,0.000019072138,0.00003176922,0.9979035,0.00013303586,0.00013389856,0.000012318205],"study_design_scores_gemma":[0.00027117014,0.00015821082,0.002774389,0.000607579,0.00012452847,7.727596e-9,0.000006285479,0.0005205359,0.9943864,0.0000026867167,0.0007044347,0.00044379293],"about_ca_topic_score_codex":0.000046581772,"about_ca_topic_score_gemma":0.0000048730753,"teacher_disagreement_score":0.0035171665,"about_ca_system_score_codex":0.00012103272,"about_ca_system_score_gemma":0.0003373075,"threshold_uncertainty_score":0.999841},"labels":[],"label_agreement":null},{"id":"W4401014484","doi":"10.1124/jpet.124.002226","title":"Comparison of the Genomic Activity of an EP4-Receptor and β2-Adrenoceptor Agonist in BEAS-2B Human Bronchial Epithelial Cells: In Search of Compartmentalized, cAMP-Dependent Gene Expression","year":2024,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Agonist; Receptor; Adrenergic receptor; Gene; Chemistry; Biology; Pharmacology; Genetics","score_opus":0.029704324071590998,"score_gpt":0.3662831807827922,"score_spread":0.3365788567112012,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401014484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936655,0.005545666,0.00005811636,0.00002433947,0.00048029816,0.00017320883,0.000043343705,0.0000011354168,0.000008396013],"genre_scores_gemma":[0.9991571,0.00030772967,0.00034636143,0.000030237617,0.00012530765,0.0000032269024,0.0000059692616,0.000013676882,0.000010399348],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987974,0.000270922,0.00047736702,0.00016139692,0.00014888206,0.00014403062],"domain_scores_gemma":[0.9995937,0.000023711744,0.00023102676,0.00007380773,0.000030614272,0.000047155805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035425043,0.00013273823,0.00033932787,0.00008062222,0.000052242878,0.0000101845835,0.00016136665,0.00012158194,0.00009549397],"category_scores_gemma":[8.4048685e-7,0.00010132703,0.00008334049,0.000051989515,0.00021375967,0.000014892356,0.00011371932,0.00021323812,1.3866253e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010440466,0.0006790028,0.0021336146,0.00004445686,0.00010141036,0.0000022673032,0.0016344858,0.00023214922,0.99355465,0.0000117884165,0.000020298894,0.00054180244],"study_design_scores_gemma":[0.0018973809,0.0010626627,0.0005586616,0.000037890375,0.00003774379,0.000014133633,0.0010142338,0.00037272618,0.9947084,0.000015459227,0.00019199321,0.0000887102],"about_ca_topic_score_codex":0.000028027152,"about_ca_topic_score_gemma":0.000012861035,"teacher_disagreement_score":0.0054915952,"about_ca_system_score_codex":0.000042583568,"about_ca_system_score_gemma":0.00008077535,"threshold_uncertainty_score":0.41319963},"labels":[],"label_agreement":null},{"id":"W4401461538","doi":"10.1080/10408363.2024.2358304","title":"G protein-coupled receptor (GPCR) pharmacogenomics","year":2024,"lang":"en","type":"review","venue":"Critical Reviews in Clinical Laboratory Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital","funders":"Danmarks Frie Forskningsfond; Lundbeckfonden","keywords":"Pharmacogenomics; G protein-coupled receptor; Computational biology; Receptor; Chemistry; Pharmacology; Bioinformatics; Biology; Genetics","score_opus":0.15986998363797228,"score_gpt":0.49371082697802887,"score_spread":0.3338408433400566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401461538","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012533915,0.9953696,0.00012724701,0.000088205124,0.0024825095,0.0013834299,0.00012019079,0.000025054851,0.00027839886],"genre_scores_gemma":[0.000021008387,0.99340147,0.0037487855,0.00045183348,0.00162636,0.00038943955,0.00005591015,0.000065637854,0.00023956863],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9931002,0.0014071128,0.0027741897,0.0016736571,0.0003669996,0.0006778327],"domain_scores_gemma":[0.99813944,0.00042248482,0.00033349756,0.0005911476,0.00014005823,0.00037336242],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.009386857,0.0006416022,0.0023726544,0.0001506307,0.000153855,0.00021651233,0.0011948074,0.0008377846,0.000434009],"category_scores_gemma":[0.0078092557,0.00044123683,0.0010689344,0.0010331622,0.0010361096,0.000015653322,0.00039222307,0.0010796586,0.0009758621],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014420403,0.0002681535,0.000005362072,0.019388111,0.00008623806,0.00003621231,0.000008550988,4.572137e-7,0.0023502745,0.0065691182,0.008137986,0.9631351],"study_design_scores_gemma":[0.00008673719,0.00030098268,6.448322e-8,0.0116886925,0.00026865053,0.000003940629,0.000008264194,0.000018914927,0.00012825978,0.00028134006,0.9866722,0.00054194283],"about_ca_topic_score_codex":0.0000015928233,"about_ca_topic_score_gemma":0.0000035938108,"teacher_disagreement_score":0.9785342,"about_ca_system_score_codex":0.00005273552,"about_ca_system_score_gemma":0.0014289168,"threshold_uncertainty_score":0.99980396},"labels":[],"label_agreement":null},{"id":"W4401578078","doi":"10.7554/elife.99373","title":"Endosomal chemokine receptor signalosomes regulate central mechanisms underlying cell migration","year":2024,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"National Institute of General Medical Sciences; Japan Society for the Promotion of Science; LEO Fondet; Biotechnology and Biological Sciences Research Council; Wellcome Trust; National Cancer Institute; Daiichi Sankyo Foundation of Life Science; Japan Science and Technology Agency; Uehara Memorial Foundation","keywords":"Endosome; Chemokine receptor; Cell biology; Chemokine; CCL25; CC chemokine receptors; Receptor; Cell migration; Cell; Biology; Genetics; Intracellular","score_opus":0.01245089612734895,"score_gpt":0.23868650334740302,"score_spread":0.22623560722005406,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401578078","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91849923,0.0033785698,0.07480307,0.00053133524,0.0014421862,0.00026167207,0.00003438503,0.00012842217,0.00092111237],"genre_scores_gemma":[0.9907636,0.00037539686,0.0050616316,0.000226667,0.00050172186,0.00002006047,0.00027587728,0.00005141003,0.002723608],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986444,0.000045394136,0.00023896708,0.00045298453,0.0002471388,0.00037110655],"domain_scores_gemma":[0.999549,0.0000123727705,0.000048813457,0.00021383983,0.00005005325,0.00012596871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017366787,0.00020694904,0.00014628266,0.000057317444,0.00010185157,0.00011542999,0.00014727356,0.00018271558,0.00050097133],"category_scores_gemma":[0.000019496001,0.00019245013,0.00015399815,0.00011587173,0.000022010938,0.000011051174,0.00006054808,0.000121955076,0.00008052471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024683992,0.000023524008,0.000014223643,0.00004026085,0.000038671293,0.0000058742526,0.00008935872,0.00013417154,0.9929103,0.0018300023,0.0031756498,0.0017132359],"study_design_scores_gemma":[0.00022129664,0.00017297185,0.000034020595,0.000041453997,0.000020541305,0.000008501571,0.00009588423,0.0012831907,0.9513814,0.00042029918,0.046088774,0.00023167655],"about_ca_topic_score_codex":0.00001508547,"about_ca_topic_score_gemma":0.000008597819,"teacher_disagreement_score":0.07226438,"about_ca_system_score_codex":0.000029695782,"about_ca_system_score_gemma":0.000085436026,"threshold_uncertainty_score":0.78478885},"labels":[],"label_agreement":null},{"id":"W4401580119","doi":"10.7554/elife.99373.1","title":"Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration","year":2024,"lang":"en","type":"preprint","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"","keywords":"Cell biology; Chemokine receptor; Endosome; G protein-coupled receptor; CCR1; Chemotaxis; CCL21; C-C chemokine receptor type 7; Biology; Signal transduction; C-C chemokine receptor type 6; Receptor; Chemokine; Chemistry; Biochemistry","score_opus":0.016615124470260673,"score_gpt":0.2485366383298133,"score_spread":0.23192151385955262,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401580119","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96001375,0.006025404,0.026417453,0.00074101816,0.004366397,0.0007626199,0.00021597759,0.00017447722,0.0012829171],"genre_scores_gemma":[0.9829022,0.0009618264,0.009167505,0.0002766781,0.0011702917,0.00008292041,0.0016175439,0.0001373189,0.0036837042],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99731755,0.000095173804,0.000506259,0.0010494909,0.00045302798,0.0005785024],"domain_scores_gemma":[0.9988363,0.000012358251,0.00023248707,0.0005826919,0.00012715765,0.00020901323],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028099315,0.00053271285,0.00040374743,0.00010988534,0.0001189921,0.00020004356,0.00039326647,0.0007894053,0.00043966342],"category_scores_gemma":[0.00003481519,0.00052496593,0.0004124631,0.00009562921,0.00003780366,0.0000042811735,0.0008554976,0.0005993313,0.00010541861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004854987,0.00004770148,0.000009224377,0.00023253217,0.00012781697,0.00000846585,0.00012834281,0.0009925665,0.9920175,0.0008688492,0.0046521816,0.0008662451],"study_design_scores_gemma":[0.00031000224,0.00016748226,0.000019544887,0.00017931919,0.00008872842,0.0000068649456,0.00010599559,0.0011481121,0.9800576,0.0040431214,0.013293217,0.0005800021],"about_ca_topic_score_codex":0.000049306513,"about_ca_topic_score_gemma":0.000021878677,"teacher_disagreement_score":0.022888474,"about_ca_system_score_codex":0.00007632929,"about_ca_system_score_gemma":0.00027734917,"threshold_uncertainty_score":0.9997202},"labels":[],"label_agreement":null},{"id":"W4401713328","doi":"10.1016/j.slasd.2024.100177","title":"Development of a time-resolved fluorescence resonance energy transfer ultra-high throughput screening assay targeting SYK and FCER1G interaction","year":2024,"lang":"en","type":"article","venue":"SLAS DISCOVERY","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Cancer Institute; Emory University; National Institute on Aging; Istituto Superiore di Sanità; University of Toronto; University of Oxford","keywords":"Förster resonance energy transfer; Energy transfer; Fluorescence; Throughput; High-throughput screening; Syk; Chemistry; Computer science; Physics; Optics; Telecommunications; Chemical physics; Biochemistry","score_opus":0.008751320385448184,"score_gpt":0.2281399771055996,"score_spread":0.21938865672015143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401713328","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6555968,0.0038401913,0.3398516,0.000027392063,0.00026850254,0.000062237246,0.00002082812,0.000020863503,0.00031161436],"genre_scores_gemma":[0.9870173,0.00043422903,0.011428036,0.000039236136,0.0001599254,0.000015185741,0.00011829264,0.000028440078,0.00075936207],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892014,0.000049669266,0.0002813484,0.00039361708,0.00015279575,0.00020244428],"domain_scores_gemma":[0.9997415,0.000030520805,0.00003314957,0.00012162016,0.000032429052,0.00004079377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002554475,0.00016173524,0.00015821225,0.000042298616,0.00008266206,0.000083651044,0.00009570709,0.000106020925,0.00004345743],"category_scores_gemma":[0.000029218074,0.000144426,0.00007360368,0.00008246769,0.000041837517,0.00003401618,0.0000440511,0.00009072565,0.0000025531367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000665706,0.000016847573,0.00003134216,0.000043258733,0.00006145491,0.0000035108305,0.00034595316,0.00005436173,0.9724476,0.0007523064,0.00020256237,0.025974268],"study_design_scores_gemma":[0.00016230046,0.000066613946,0.00005150315,0.00025863157,0.000015462228,0.0000055252763,0.00017672741,0.00068820757,0.9695085,0.000056057666,0.028828433,0.00018198388],"about_ca_topic_score_codex":0.000048828148,"about_ca_topic_score_gemma":0.000022774724,"teacher_disagreement_score":0.3314205,"about_ca_system_score_codex":0.000015649322,"about_ca_system_score_gemma":0.000080984355,"threshold_uncertainty_score":0.5889521},"labels":[],"label_agreement":null},{"id":"W4401820452","doi":"10.1139/cjpp-2024-0265","title":"Retraction: β-arrestin-1 mediates the endothelin-1-induced activation of Akt and integrin-linked kinase","year":2024,"lang":"en","type":"retraction","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":true,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Protein kinase B; Integrin; Cell biology; Arrestin; Chemistry; Kinase; Endothelin 1; Internal medicine; Signal transduction; Biology; Medicine; Biochemistry; G protein-coupled receptor; Receptor","score_opus":0.01861895602927667,"score_gpt":0.27807186885900914,"score_spread":0.2594529128297325,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401820452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9717814,0.01666819,0.000054166,0.0010974059,0.009929067,0.00021732204,0.000077351375,0.0000032632838,0.00017183798],"genre_scores_gemma":[0.98812234,0.0074013993,0.000049674858,0.0003266725,0.003571763,0.0000074237682,0.00006471118,0.000027711063,0.00042830672],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998807,0.00024041404,0.0004085272,0.00024356632,0.00007821252,0.00022227722],"domain_scores_gemma":[0.9988392,0.00015167336,0.00047541616,0.000101547324,0.0002257789,0.0002063884],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045457983,0.00021450764,0.0003760814,0.00020803855,0.00013218148,0.00001627874,0.00016792423,0.0008128215,0.0005625867],"category_scores_gemma":[0.0001103286,0.00015694769,0.0001183799,0.00007683419,0.00022216569,0.000010084909,0.000028951927,0.0011223656,0.0000019992483],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011475545,0.000012205951,0.000013067143,0.00018237584,0.00029854625,0.00001481977,0.00011717296,0.000019486597,0.9847631,0.000045154677,0.010186922,0.0042324252],"study_design_scores_gemma":[0.00039105536,0.00075994816,0.00009696872,0.00010759814,0.00026467984,0.00021029814,0.000118174714,0.000044917244,0.8801556,0.0006899951,0.11699672,0.00016401643],"about_ca_topic_score_codex":0.0004471538,"about_ca_topic_score_gemma":0.00028598984,"teacher_disagreement_score":0.106809795,"about_ca_system_score_codex":0.000035170873,"about_ca_system_score_gemma":0.0008683214,"threshold_uncertainty_score":0.6400141},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":["research_integrity"],"domain":null,"study_design":"not_applicable","genre":"editorial","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"split"},{"id":"W4401830302","doi":"10.1016/j.cellsig.2024.111358","title":"Understanding the impact of nuclear-localized GPCRs on cellular signalling","year":2024,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Courtois Foundation","keywords":"G protein-coupled receptor; Endosome; Signalling; Receptor; Cell biology; Biology; Signal transduction; Signalling pathways; Computational biology; Biochemistry","score_opus":0.09231620280239398,"score_gpt":0.3144668460483334,"score_spread":0.22215064324593942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401830302","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00060742086,0.9376073,0.059571683,0.0000073337274,0.0005362502,0.00082217436,0.00005610401,0.000052407184,0.00073935796],"genre_scores_gemma":[0.061322287,0.9362421,0.00025442446,0.000028483008,0.0009892888,0.000038425755,0.00041147013,0.00037418783,0.0003393029],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9960985,0.00042762258,0.0011604459,0.0010713044,0.00052916416,0.00071297213],"domain_scores_gemma":[0.99814904,0.00014712871,0.00065084134,0.0007651225,0.000088263936,0.000199592],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011770803,0.0009946037,0.0016294302,0.00027667877,0.00031090213,0.0002169006,0.00095905754,0.0008708466,0.0004190535],"category_scores_gemma":[0.00006305073,0.00063766056,0.00278394,0.0004699592,0.00015616322,0.000007075116,0.0002659628,0.0009405539,0.00011291823],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017060789,0.00024019813,6.62356e-7,0.011737535,0.0050198915,0.00019041025,0.00043310347,0.01280789,0.9240135,0.00514613,0.002432477,0.037807606],"study_design_scores_gemma":[0.0010593461,0.0025112338,2.7769158e-8,0.03663698,0.0060580443,0.00007103433,0.00073450187,0.008864902,0.11464887,0.0033880817,0.82243264,0.0035943247],"about_ca_topic_score_codex":0.000023324365,"about_ca_topic_score_gemma":8.2136285e-7,"teacher_disagreement_score":0.8200002,"about_ca_system_score_codex":0.00025868762,"about_ca_system_score_gemma":0.00039125793,"threshold_uncertainty_score":0.99960744},"labels":[],"label_agreement":null},{"id":"W4401994983","doi":"10.14293/p2199-8442.1.sop-.pa3hbr.v1","title":"Mechanisms of neurotransmitter receptor subunit compatibility","year":2024,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neurotransmitter receptor; Neurotransmitter; Compatibility (geochemistry); Neurotransmitter systems; Receptor; Protein subunit; Chemistry; Neuroscience; Psychology; Biochemistry; Materials science; Gene","score_opus":0.01676205323655472,"score_gpt":0.2569240498688994,"score_spread":0.24016199663234467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401994983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89890254,0.00077325915,0.09280893,0.00027949768,0.0020352812,0.00063527346,0.00023256024,0.000064166656,0.0042684926],"genre_scores_gemma":[0.98834854,0.00010458958,0.009188803,0.00023680234,0.0001748243,0.000037021007,0.00037093423,0.000062384264,0.0014761076],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99821377,0.000104465886,0.000473577,0.0007506432,0.00022546452,0.00023210948],"domain_scores_gemma":[0.99889094,0.000011347484,0.0001281844,0.0007363427,0.00014371713,0.00008945671],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000341114,0.00032513874,0.0003818998,0.00007140326,0.000028915627,0.000040069095,0.00038753563,0.0005028466,0.0013906545],"category_scores_gemma":[0.000022507313,0.00028534298,0.00037250924,0.00006461127,0.000055140514,8.8757537e-7,0.0008701225,0.00044350958,0.00004687578],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044090742,0.000055339322,0.000020198217,0.0004253472,0.00011446871,0.0000014160636,0.00004118816,0.00015064144,0.9933047,0.0027304376,0.002047738,0.0010644348],"study_design_scores_gemma":[0.00013334326,0.00020037942,0.000028552624,0.00009826166,0.000053052947,0.0000022492102,0.000035846562,0.00036083895,0.9657244,0.03016516,0.0028906742,0.0003072381],"about_ca_topic_score_codex":0.00008296722,"about_ca_topic_score_gemma":0.000017936803,"teacher_disagreement_score":0.08944599,"about_ca_system_score_codex":0.000012134045,"about_ca_system_score_gemma":0.00013369702,"threshold_uncertainty_score":0.9999599},"labels":[],"label_agreement":null},{"id":"W4402031318","doi":"10.1021/acssensors.4c00806","title":"Class-Wide Analysis of Frizzled-Dishevelled Interactions Using BRET Biosensors Reveals Functional Differences among Receptor Paralogs","year":2024,"lang":"en","type":"article","venue":"ACS Sensors","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Innovative Medicines Initiative; Horizon 2020 Framework Programme; Novo Nordisk Fonden; Vetenskapsrådet; Cancerfonden; Karolinska Institutet; European Commission; Kungliga Tekniska Högskolan; Deutsche Forschungsgemeinschaft; Diamond Light Source; Novo Nordisk; European Federation of Pharmaceutical Industries and Associations; McGill University","keywords":"Dishevelled; Frizzled; Computational biology; Biology; Biosensor; Receptor; Class (philosophy); Evolutionary biology; Neuroscience; Cell biology; Genetics; Signal transduction; Computer science; Biochemistry; Wnt signaling pathway; Artificial intelligence","score_opus":0.024755442204237654,"score_gpt":0.26589778209956155,"score_spread":0.2411423398953239,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402031318","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99491495,0.00032757534,0.0034571332,0.00008765999,0.0007042501,0.00012195912,0.00009388606,0.00003393965,0.0002586387],"genre_scores_gemma":[0.996478,0.000120890596,0.0008756907,0.000058618873,0.00020158188,0.000005771545,0.00025799513,0.000029101939,0.001972351],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99843764,0.00013062962,0.00044847652,0.0004999806,0.00022139131,0.0002618741],"domain_scores_gemma":[0.9992298,0.00012176817,0.00013613162,0.0002872071,0.00013029657,0.00009483085],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00021577503,0.00022573212,0.00036923436,0.00032678328,0.00011208128,0.000067902016,0.000135385,0.0001869096,0.000989774],"category_scores_gemma":[0.00013584114,0.00019801871,0.00037327353,0.00054039917,0.00010592974,0.000015683467,0.0000663921,0.0001609621,0.000019151068],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045545272,0.000033686007,0.019176716,0.000024162078,0.001460777,0.0000035284286,0.00018838726,0.002757861,0.97466224,0.00017348268,0.0013436489,0.00012998047],"study_design_scores_gemma":[0.00034162094,0.000241332,0.031089274,0.00017536581,0.0016454316,0.000017331195,0.0011093618,0.022668492,0.93675715,0.00033841075,0.004886939,0.00072930264],"about_ca_topic_score_codex":0.00009561227,"about_ca_topic_score_gemma":0.00006313072,"teacher_disagreement_score":0.037905086,"about_ca_system_score_codex":0.000029167542,"about_ca_system_score_gemma":0.000048599293,"threshold_uncertainty_score":0.99992347},"labels":[],"label_agreement":null},{"id":"W4402217106","doi":"10.1007/s00018-024-05416-8","title":"G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors","year":2024,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Sherbrooke","funders":"National Institute of General Medical Sciences; National Cancer Institute; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Downstream (manufacturing); Effector; Selectivity; Chemistry; Cell biology; Downstream processing; Biophysics; Molecular biology; Biochemistry; Biology; Business","score_opus":0.006143262088120926,"score_gpt":0.2328060081819287,"score_spread":0.22666274609380777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402217106","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9875128,0.009951062,0.0012594282,0.000041608117,0.00013218331,0.0004204089,0.000008059972,0.00001726786,0.00065718463],"genre_scores_gemma":[0.99947304,0.000071681585,0.00018622872,0.00003920258,0.000062863095,0.00003382561,0.000010164317,0.000013901317,0.00010907341],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99878824,0.00014020679,0.00013322641,0.00051291304,0.00020857675,0.00021685864],"domain_scores_gemma":[0.9996676,0.000028637203,0.000039805876,0.00011998261,0.000028820526,0.00011516877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00065413816,0.00017344185,0.00017813018,0.00008287003,0.000118378295,0.000057494046,0.00011265775,0.00010991544,0.000018595627],"category_scores_gemma":[0.00013561935,0.0001302345,0.00007480541,0.00018815753,0.00015547764,0.000008632672,0.00007534617,0.000088998924,0.0000036556162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023677165,0.000017781125,0.0000917838,0.00017218068,0.000029248024,0.000007770166,0.000027701659,0.000013794251,0.9954811,0.0010812894,0.000036316484,0.0030173545],"study_design_scores_gemma":[0.00016138652,0.0018015214,0.000032161417,0.000109126464,0.000020826745,0.0000062448426,0.000015061823,0.00091168674,0.9959031,0.00010430303,0.0007780598,0.00015656263],"about_ca_topic_score_codex":0.000010350667,"about_ca_topic_score_gemma":8.8918046e-7,"teacher_disagreement_score":0.0119602615,"about_ca_system_score_codex":0.0000041951407,"about_ca_system_score_gemma":0.00008035426,"threshold_uncertainty_score":0.53108084},"labels":[],"label_agreement":null},{"id":"W4402270139","doi":"10.21203/rs.3.rs-4869264/v1","title":"G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Downstream (manufacturing); Effector; Chemistry; Selectivity; Cell biology; Biophysics; Business; Biochemistry; Biology","score_opus":0.020204454781610637,"score_gpt":0.34526742477761274,"score_spread":0.3250629699960021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402270139","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926123,0.0031706395,0.000024102816,0.000045235076,0.00016551699,0.0025933625,0.0001707856,0.000026489452,0.0011915418],"genre_scores_gemma":[0.99769247,0.00012981231,0.000072128605,0.0000032836747,0.0003259812,0.0006699696,0.00017706882,0.00006153315,0.0008677398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996946,0.000836126,0.00022259969,0.0008994391,0.00062306976,0.00047276358],"domain_scores_gemma":[0.998866,0.00012077349,0.00007777743,0.00049325475,0.0002895711,0.00015257765],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0020222445,0.00031679042,0.00039620118,0.00023400909,0.00010375858,0.00008078971,0.0002628061,0.0005941127,0.0000826423],"category_scores_gemma":[0.00060920254,0.00025423127,0.00019060275,0.00020236868,0.00008385755,0.0000019599968,0.0012219129,0.0011768829,0.000035303212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002794401,0.000083013,0.00016666006,0.0048078927,0.00012679207,0.000011482927,0.000045897872,0.000030415742,0.9865469,0.00027493853,0.0004283189,0.007198295],"study_design_scores_gemma":[0.0002649253,0.003666294,0.00018003258,0.0015007276,0.000017162907,0.0000030793335,0.000014776503,0.00029142958,0.99271375,0.00056480395,0.0005531907,0.00022979929],"about_ca_topic_score_codex":0.00007709788,"about_ca_topic_score_gemma":0.0000120887,"teacher_disagreement_score":0.006968496,"about_ca_system_score_codex":0.00005634677,"about_ca_system_score_gemma":0.0002735576,"threshold_uncertainty_score":0.999991},"labels":[],"label_agreement":null},{"id":"W4402276553","doi":"10.1038/s41593-024-01748-7","title":"Sex-biased neural encoding of threat discrimination in nucleus accumbens afferents drives suppression of reward behavior","year":2024,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University","funders":"Canadian Institutes of Health Research; Ludmer Centre for Neuroinformatics and Mental Health; Government of Canada","keywords":"Nucleus accumbens; Neuroscience; Glutamatergic; Prefrontal cortex; Psychology; Hippocampus; Ventral pallidum; Glutamate receptor; Central nervous system; Biology; Basal ganglia; Cognition","score_opus":0.017995581858671016,"score_gpt":0.308186513344704,"score_spread":0.290190931486033,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402276553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99816006,0.00030925465,0.00033856838,0.00003651809,0.0009196522,0.00012561402,0.00002211872,0.000008741001,0.00007944726],"genre_scores_gemma":[0.9995648,0.00007527339,0.00016298269,0.000038182316,0.000039340728,0.000006169449,0.00001714229,0.000010526838,0.00008553115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990751,0.000042692103,0.00017626495,0.00033902374,0.00022042466,0.00014648383],"domain_scores_gemma":[0.9996956,0.000015821332,0.000057712354,0.00016218015,0.00003411832,0.000034554865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012096327,0.000099378245,0.00011774024,0.0000880987,0.000032072323,0.000023811686,0.00021861588,0.00016331718,0.00000888575],"category_scores_gemma":[0.00011756305,0.00008127954,0.00006345353,0.00018859217,0.00007549134,0.000019059065,0.00009069307,0.00019245128,1.7004852e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013783674,0.000041916526,0.003016622,0.000035419187,7.3322525e-7,0.0000066641082,0.000119832854,0.000080727936,0.9944969,0.00011513655,0.00003085193,0.0020414123],"study_design_scores_gemma":[0.000115340394,0.00016267673,0.010825789,0.00008143944,0.000008792808,0.0000058404094,0.000059431197,0.0016286535,0.9868671,0.00004912912,0.000118285876,0.00007756904],"about_ca_topic_score_codex":0.000007734634,"about_ca_topic_score_gemma":0.000008314887,"teacher_disagreement_score":0.007809167,"about_ca_system_score_codex":0.000007883404,"about_ca_system_score_gemma":0.000029013481,"threshold_uncertainty_score":0.33144835},"labels":[],"label_agreement":null},{"id":"W4402313779","doi":"10.1038/s44318-024-00223-0","title":"Histamine synthesis and transport are coupled in axon terminals via a dual quality control system","year":2024,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Directorate for Biological Sciences; Ministry of Science and Technology of the People's Republic of China; Institute of Genetics; National Natural Science Foundation of China","keywords":"Biology; Dual (grammatical number); Cell biology; Axon; Histamine; Quality (philosophy); Neuroscience; Endocrinology","score_opus":0.010999506277942515,"score_gpt":0.24813546456065982,"score_spread":0.2371359582827173,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402313779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98374075,0.0036522865,0.011788799,0.00031953643,0.00027023724,0.00011447805,0.000017404509,0.00001027339,0.00008621838],"genre_scores_gemma":[0.9991641,0.00016468212,0.00007199541,0.0000640977,0.00037671943,0.000013080019,0.0000029896537,0.000016229742,0.00012610706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899936,0.00016403735,0.0003278855,0.00017611746,0.00014656897,0.00018604434],"domain_scores_gemma":[0.999612,0.000060925177,0.00009265494,0.00012703626,0.00003687602,0.00007055508],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013699783,0.00012445648,0.00021818868,0.000043187203,0.000097247714,0.000058673562,0.00010181769,0.000077215,0.00005277062],"category_scores_gemma":[0.0000377968,0.00008097059,0.000097413285,0.000050440165,0.00003674164,0.0000051231405,0.000013004496,0.00018773947,0.000002515788],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019940193,0.000026449832,0.0009312297,0.00014651769,0.00011551452,0.00022302105,0.00019670214,0.00007733949,0.9945254,0.0001737973,0.00009202235,0.0032926104],"study_design_scores_gemma":[0.0067902473,0.0014249883,0.044357173,0.004430498,0.001078755,0.014845636,0.010098528,0.04034444,0.85660887,0.0015267305,0.01624449,0.0022496234],"about_ca_topic_score_codex":0.000029727084,"about_ca_topic_score_gemma":0.00003076002,"teacher_disagreement_score":0.1379165,"about_ca_system_score_codex":0.000029599867,"about_ca_system_score_gemma":0.000046041263,"threshold_uncertainty_score":0.33018848},"labels":[],"label_agreement":null},{"id":"W4402687011","doi":"10.7554/elife.101105.1.sa3","title":"eLife Assessment: Ultraslow serotonin oscillations in the hippocampus delineate substates across NREM and waking","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"Hippocampus; Serotonin; Non-rapid eye movement sleep; Neuroscience; Physics; Psychology; Internal medicine; Electroencephalography; Medicine","score_opus":0.023398720736376468,"score_gpt":0.35143517420355114,"score_spread":0.3280364534671747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402687011","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.2691083,0.61281145,0.014294539,0.0682693,0.007990656,0.007051965,0.0027328099,0.00021738526,0.017523643],"genre_scores_gemma":[0.4656768,0.3847584,0.009399025,0.023463145,0.0033266793,0.0011076654,0.016783258,0.0004165555,0.095068455],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979842,0.00015709165,0.0004883723,0.0006550087,0.00031953727,0.0003958272],"domain_scores_gemma":[0.99919,0.000058298112,0.00013039366,0.00041041835,0.00014605376,0.00006487416],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012411433,0.00037189305,0.00039043382,0.000048601054,0.0001531909,0.00021617408,0.00031671126,0.00034755454,0.00015545731],"category_scores_gemma":[0.00006110828,0.00025012987,0.00017009891,0.00018912498,0.00005418227,0.000004521526,0.00014896557,0.0004565468,0.000012056897],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002977179,0.0001363873,0.00047111567,0.0053020664,0.0005356045,0.0000811546,0.0008769221,0.00033908463,0.09130039,0.00071255735,0.7784718,0.12174309],"study_design_scores_gemma":[0.000199226,0.00008794435,0.00004187164,0.0012964397,0.000095742165,0.000050489445,0.00032324044,0.0005074641,0.0043556243,0.0006922477,0.99191415,0.0004355511],"about_ca_topic_score_codex":0.00013659582,"about_ca_topic_score_gemma":0.0007633945,"teacher_disagreement_score":0.228053,"about_ca_system_score_codex":0.000025383488,"about_ca_system_score_gemma":0.00014606728,"threshold_uncertainty_score":0.9999951},"labels":[],"label_agreement":null},{"id":"W4402722805","doi":"10.1111/dom.15940","title":"A novel, centrally acting mammalian aminosterol, <scp>ENT</scp> ‐03, induces weight loss in obese and lean rodents","year":2024,"lang":"en","type":"article","venue":"Diabetes Obesity and Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Weston Family Foundation; Weston Brain Institute","keywords":"Medicine; Weight loss; Pharmacology; Cell biology; Endocrinology; Internal medicine; Obesity; Biology","score_opus":0.008218874300047111,"score_gpt":0.2178197142001367,"score_spread":0.2096008399000896,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402722805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98541355,0.013487664,0.00013012919,0.000057596353,0.00051295833,0.00017090532,0.000037176942,0.000024124565,0.00016591007],"genre_scores_gemma":[0.9965125,0.0019237364,0.00045558714,0.00023841257,0.0003550362,0.000013634883,0.000060741488,0.000030323221,0.00041004908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985036,0.000051203762,0.00024297334,0.0005568432,0.00015740347,0.00048792467],"domain_scores_gemma":[0.9995322,0.00003661085,0.00005630376,0.00017020204,0.000033186454,0.00017147786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035534424,0.00025593303,0.00028634403,0.00011662467,0.000112918846,0.00017885289,0.00015148178,0.00022783625,0.000015032078],"category_scores_gemma":[0.0000809035,0.00023566064,0.000075928016,0.00013691265,0.00006808218,0.000035432746,0.00019060636,0.00021692476,0.0000076679935],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000051033585,0.00008516959,0.033018272,0.00015184337,0.000080041566,0.00001671622,0.00056589785,0.0000041376343,0.9585891,0.00037813897,0.0000958851,0.0070097204],"study_design_scores_gemma":[0.00079914316,0.00006768421,0.115667835,0.00016756965,0.000079582715,0.000010481576,0.00020309431,0.00017423567,0.849071,0.00032155833,0.033222593,0.0002151672],"about_ca_topic_score_codex":0.00003742124,"about_ca_topic_score_gemma":0.000031759693,"teacher_disagreement_score":0.10951802,"about_ca_system_score_codex":0.000008511958,"about_ca_system_score_gemma":0.000030953008,"threshold_uncertainty_score":0.9609962},"labels":[],"label_agreement":null},{"id":"W4402751504","doi":"10.1111/gtc.13164","title":"The repertoire of G‐protein‐coupled receptor variations in the Japanese population 54KJPN","year":2024,"lang":"en","type":"article","venue":"Genes to Cells","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Science and Technology Agency; Japan Society for the Promotion of Science; Institute of Genetics; Japan Agency for Medical Research and Development","keywords":"Biology; Repertoire; Receptor; Population; Evolutionary biology; Computational biology; Genetics; Zoology; Demography; Sociology","score_opus":0.0072790107935697,"score_gpt":0.23545468576063247,"score_spread":0.22817567496706276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402751504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99421835,0.0028192268,0.0012870224,0.000704516,0.00041447778,0.0003715559,0.0000112531125,0.000009047892,0.00016453507],"genre_scores_gemma":[0.99752825,0.0001614162,0.0006587605,0.00010487531,0.00021816338,0.000059994585,0.000047708592,0.000013498063,0.0012073527],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99923235,0.000087375796,0.00021497742,0.00019661673,0.00013264158,0.00013602391],"domain_scores_gemma":[0.99958605,0.000034318782,0.000036606216,0.0002831369,0.000036168894,0.000023729683],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004891046,0.000084147476,0.00007519699,0.000029367504,0.000097460485,0.000054148208,0.00019563796,0.00007660899,0.00005567193],"category_scores_gemma":[0.000040272887,0.00005031166,0.000067038716,0.00016873587,0.000013761506,0.0000030635908,0.000041509953,0.000052896197,0.000015823183],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015546659,0.000011384553,0.000017448834,0.000012667209,0.000013535678,5.6592353e-7,0.00039122152,0.00033746308,0.9932416,0.00040042872,0.00051797484,0.00504014],"study_design_scores_gemma":[0.000101950274,0.00015977492,0.00014449954,0.000039978622,0.000013186361,0.0000023974205,0.00055861584,0.0012187383,0.92989063,0.00025948763,0.06747991,0.00013085532],"about_ca_topic_score_codex":0.00018778378,"about_ca_topic_score_gemma":0.000090331145,"teacher_disagreement_score":0.06696194,"about_ca_system_score_codex":0.0000101327105,"about_ca_system_score_gemma":0.000027018412,"threshold_uncertainty_score":0.205165},"labels":[],"label_agreement":null},{"id":"W4402802804","doi":"10.21203/rs.3.rs-5024207/v1","title":"A red fluorescent genetically encoded biosensor for in vivo imaging of extracellular L-lactate dynamics","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Precursory Research for Embryonic Science and Technology; National Institutes of Health; Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering; Japan Society for the Promotion of Science; Imperial College London; Medical Research Council; Kanazawa University; Japan Science and Technology Agency; UK Dementia Research Institute; Precise Measurement Technology Promotion Foundation; Montana State University","keywords":"Fluorescence; Biosensor; In vivo; Fluorescent protein; Extracellular; Green fluorescent protein; Chemistry; Dynamics (music); Biophysics; Biochemistry; Cell biology; Biology; Genetics; Gene; Psychology; Physics; Optics","score_opus":0.026879520007912695,"score_gpt":0.34377872804241105,"score_spread":0.31689920803449834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402802804","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9723141,0.010362881,0.011975999,0.0007912164,0.0005168241,0.0026221708,0.00084034394,0.000029531086,0.0005469318],"genre_scores_gemma":[0.9892872,0.0011082091,0.007859076,0.00000899148,0.00026497763,0.00026561864,0.00042172463,0.00009993633,0.0006842893],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9970195,0.00026104262,0.00056904875,0.0009158659,0.0005441189,0.0006904145],"domain_scores_gemma":[0.9984062,0.000071993214,0.00010197935,0.00066989975,0.0005999647,0.00014996715],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016072637,0.00029181238,0.000386861,0.00037342476,0.00006232729,0.00009404268,0.0004745239,0.00042484634,0.00007070963],"category_scores_gemma":[0.00036224228,0.00028610937,0.00031881098,0.00019968807,0.00013399542,0.0000017233758,0.0011999983,0.00074285455,0.000004345576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024371584,0.000109125045,0.00017992788,0.0018488668,0.000064930595,0.00003507394,0.00010370841,0.00056699634,0.99262697,0.0009998765,0.0005927906,0.0026280303],"study_design_scores_gemma":[0.00047231044,0.00027336658,0.000033486183,0.0008952566,0.000021384116,0.000004226723,0.00031924984,0.06352103,0.9261493,0.0064307665,0.0015611179,0.00031849404],"about_ca_topic_score_codex":0.000075014046,"about_ca_topic_score_gemma":0.00008115792,"teacher_disagreement_score":0.06647765,"about_ca_system_score_codex":0.00014327644,"about_ca_system_score_gemma":0.00046554435,"threshold_uncertainty_score":0.9999591},"labels":[],"label_agreement":null},{"id":"W4403587269","doi":"10.1038/s41380-024-02790-4","title":"Npbwr1 signaling mediates fast antidepressant action","year":2024,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Leibniz-Gemeinschaft; Universitätsklinikum Jena; Australian Government","keywords":"Antidepressant; Nucleus accumbens; Depression (economics); Chronic stress; Major depressive disorder; Psychology; Biomarker; Mood; Medicine; Neuroscience; Internal medicine; Psychiatry; Receptor; Hippocampus; Biology","score_opus":0.008736920264705052,"score_gpt":0.2613359905596124,"score_spread":0.2525990702949073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403587269","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8921202,0.016347954,0.08601196,0.00042863126,0.0034086863,0.00017595135,0.000016027385,0.000112318594,0.00137829],"genre_scores_gemma":[0.99324465,0.00026653789,0.0047375415,0.00038045735,0.0008421457,0.000023074866,0.00012518816,0.00006830099,0.00031210628],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986759,0.000060731323,0.00023197923,0.00052423996,0.00021020233,0.00029696352],"domain_scores_gemma":[0.9995061,0.0000067750493,0.000043005104,0.00030407502,0.000039275812,0.0001007265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001990408,0.00021491478,0.00013974356,0.0000852671,0.00009200243,0.00012382107,0.00018213497,0.00015876192,0.00019463159],"category_scores_gemma":[0.000016699405,0.00020282976,0.00021065157,0.00015237283,0.000030614123,0.000007689016,0.000066094086,0.00016813839,0.00006257604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001914761,0.000030144136,0.0002849931,0.00006990101,0.00010557129,0.000017059412,0.000021124853,0.00034974728,0.99188656,0.0017184734,0.0019942885,0.0035030094],"study_design_scores_gemma":[0.00020181296,0.00014318581,0.0000605526,0.000096708085,0.00004825428,0.000038269376,0.00012059408,0.00069137884,0.97220284,0.0016194672,0.0244591,0.00031785227],"about_ca_topic_score_codex":0.000010601867,"about_ca_topic_score_gemma":0.000006783379,"teacher_disagreement_score":0.101124465,"about_ca_system_score_codex":0.000010782749,"about_ca_system_score_gemma":0.000102885344,"threshold_uncertainty_score":0.8271158},"labels":[],"label_agreement":null},{"id":"W4403630341","doi":"10.1038/s41598-024-75838-8","title":"Functional bias of contractile control in mouse resistance arteries","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Nifedipine; Phenylephrine; Agonist; Vasoconstriction; Internal medicine; Biophysics; Coupling (piping); Endocrinology; Chemistry; Medicine; Biology; Materials science; Receptor; Calcium","score_opus":0.014002940475737745,"score_gpt":0.23060488557212738,"score_spread":0.21660194509638964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403630341","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99012905,0.0015465816,0.0036988396,0.00006306839,0.0036133942,0.00012695738,0.000011560679,0.000013410296,0.0007971388],"genre_scores_gemma":[0.98865044,0.000009143222,0.00014296664,0.000019066953,0.00007873331,0.000014568951,0.000056798737,0.0000089931455,0.011019292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989389,0.000027692435,0.00031912417,0.00039334764,0.00018511571,0.00013582146],"domain_scores_gemma":[0.9995201,0.000013811887,0.000087281995,0.00027173763,0.00007284071,0.000034232573],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000771694,0.00007417877,0.00010864017,0.00007352278,0.00004776924,0.000095826545,0.000043843975,0.00006127095,0.00019045992],"category_scores_gemma":[0.000090260226,0.0000650854,0.00007329784,0.00012360283,0.00009333467,0.000007855659,0.000016165204,0.000050763403,0.000004528651],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029500716,0.00002017294,0.0004946654,0.000023955088,0.0000131697725,0.00005697642,0.000035479166,0.00011817469,0.989251,0.00022197448,0.009499645,0.00023528941],"study_design_scores_gemma":[0.00009875048,0.0000212375,0.00020892701,0.00003417841,0.0000048491665,0.0000287281,0.000049827493,0.000106718886,0.8663968,0.001408562,0.13156332,0.000078105426],"about_ca_topic_score_codex":0.00000667043,"about_ca_topic_score_gemma":0.00005788942,"teacher_disagreement_score":0.122854196,"about_ca_system_score_codex":0.000009474788,"about_ca_system_score_gemma":0.00012092846,"threshold_uncertainty_score":0.26541054},"labels":[],"label_agreement":null},{"id":"W4403740380","doi":"10.1016/j.bpsc.2024.10.001","title":"Antipsychotic-Induced Dysregulation of Glucose Metabolism Through the Central Nervous System: A Scoping Review of Animal Models","year":2024,"lang":"en","type":"review","venue":"Biological Psychiatry Cognitive Neuroscience and Neuroimaging","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Antipsychotic; Glucose homeostasis; Energy homeostasis; Insulin resistance; Central nervous system; Carbohydrate metabolism; Endocrinology; Neurotransmitter systems; Medicine; Insulin; Animal studies; Internal medicine; Neuroscience; Biology; Pharmacology; Schizophrenia (object-oriented programming); Obesity; Dopamine; Psychiatry","score_opus":0.10332623134051663,"score_gpt":0.3699460096850864,"score_spread":0.26661977834456974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403740380","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008508953,0.98750305,0.0011146193,0.000054769756,0.0012697813,0.0013290038,0.000082088234,0.000022463479,0.000115265255],"genre_scores_gemma":[0.06137618,0.9376799,0.000121643294,0.00046944167,0.00024108599,0.000040211577,0.00003499415,0.000032888423,0.000003697928],"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","domain_scores_codex":[0.9969235,0.0004980649,0.00090797653,0.0010070375,0.00026430291,0.0003990835],"domain_scores_gemma":[0.9987811,0.00007433718,0.0006351706,0.00030616147,0.00012283953,0.00008041371],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042148176,0.00045827593,0.0011384963,0.00007482027,0.00015225873,0.00005437972,0.00041096975,0.00018758932,0.000003801573],"category_scores_gemma":[0.00017147836,0.0002678524,0.0005080544,0.0004832508,0.00033288787,0.000024595585,0.0002619317,0.00030836757,0.0000010527548],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030449452,0.00041616004,0.000035626585,0.40439412,0.00020654718,0.000037799553,0.0001449145,0.000008680732,0.29996037,0.0073590926,0.00019156732,0.2869406],"study_design_scores_gemma":[0.0008063266,0.0027372984,0.0002597355,0.9676464,0.003907428,0.00084014627,0.0003160922,0.0007356015,0.008997882,0.0009456232,0.010927081,0.0018803767],"about_ca_topic_score_codex":0.0000068400627,"about_ca_topic_score_gemma":4.6027805e-7,"teacher_disagreement_score":0.5632523,"about_ca_system_score_codex":0.0000058473092,"about_ca_system_score_gemma":0.00024194532,"threshold_uncertainty_score":0.99997735},"labels":[],"label_agreement":null},{"id":"W4404029705","doi":"10.1021/acs.jcim.4c00788","title":"Understanding and Predicting Ligand Efficacy in the μ-Opioid Receptor through Quantitative Dynamical Analysis of Complex Structures","year":2024,"lang":"en","type":"article","venue":"Journal of Chemical Information and Modeling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Opioid; Opioid receptor; Computational biology; Ligand (biochemistry); Chemistry; Computer science; Receptor; Biology; Biochemistry","score_opus":0.07721734421023392,"score_gpt":0.3213617009987585,"score_spread":0.24414435678852459,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404029705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82427603,0.00049586425,0.1750269,0.000074698415,0.000035437384,0.000037559075,0.0000063039265,0.0000016600854,0.000045539855],"genre_scores_gemma":[0.9960189,0.00033324727,0.0035013517,0.00007630492,0.000035376033,4.6108966e-7,0.000031066633,0.0000029273713,4.0068116e-7],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9992838,0.000021992419,0.00042267155,0.000059338356,0.00013804118,0.0000741906],"domain_scores_gemma":[0.99969494,0.00005921993,0.00012159249,0.000040534454,0.000057681707,0.000026053194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000350682,0.00006817483,0.00015878103,0.000110287896,0.000029268964,0.000066273766,0.000060393577,0.00007022572,0.0000051388615],"category_scores_gemma":[0.00008571867,0.00004542306,0.00007352406,0.000153751,0.00003460324,0.000045198278,0.000024720855,0.00013394126,4.7900862e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013209901,0.000018124892,0.00014671974,0.000104592036,0.000391499,6.9099343e-7,0.0077644736,0.02936502,0.9519013,0.008884797,0.000060758663,0.001229904],"study_design_scores_gemma":[0.00040984192,0.00010944753,0.000039193164,0.00010561385,0.00017749201,0.000020237065,0.0055771237,0.9435424,0.04780754,0.001916456,0.00020249056,0.00009216562],"about_ca_topic_score_codex":0.000005399265,"about_ca_topic_score_gemma":0.0000011246021,"teacher_disagreement_score":0.91417736,"about_ca_system_score_codex":0.0000147438695,"about_ca_system_score_gemma":0.000023441722,"threshold_uncertainty_score":0.18522987},"labels":[],"label_agreement":null},{"id":"W4404169423","doi":"10.1101/2024.11.07.622536","title":"The Tailtag System: Tracking Multiple Mice in a Complex Environment Over a Prolonged Period Using ArUco Markers","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; CMC Microsystems (Canada)","funders":"","keywords":"Period (music); Tracking (education); Computer science; Psychology; Philosophy","score_opus":0.015111091091496434,"score_gpt":0.2169263517815552,"score_spread":0.20181526069005876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404169423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921847,0.0042236093,0.0014060931,0.00006505804,0.00080577406,0.0010979271,0.00013103423,0.0000787718,0.0000070193864],"genre_scores_gemma":[0.99566877,0.00022499,0.003185981,0.000043541684,0.00049020856,0.00021205109,0.0000017888387,0.0001652667,0.000007375778],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969223,0.00025176027,0.0006396877,0.0011772177,0.00035242966,0.0006566015],"domain_scores_gemma":[0.9984326,0.000031267027,0.0003252549,0.00096082955,0.000092314425,0.00015776588],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00089957484,0.0005819489,0.00046035906,0.00013175714,0.00027441245,0.00037801778,0.00055921054,0.0006028899,0.000024474602],"category_scores_gemma":[0.00009951686,0.00052136945,0.00025137875,0.00017245497,0.000119984215,0.0000074247732,0.000904487,0.00072167127,0.000017468145],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000110725305,0.000046873847,0.0016590282,0.00044951457,0.00017459317,0.00005398827,0.000017732706,0.0008396588,0.99646145,0.00012525215,0.00005538994,0.0000058079827],"study_design_scores_gemma":[0.0012102756,0.00013772324,0.013794735,0.0013049202,0.000242173,4.1421058e-7,0.00012072198,0.034919746,0.93764955,0.000003928735,0.0090550445,0.0015607458],"about_ca_topic_score_codex":0.000085585336,"about_ca_topic_score_gemma":0.000017873886,"teacher_disagreement_score":0.058811862,"about_ca_system_score_codex":0.00029587344,"about_ca_system_score_gemma":0.00032539145,"threshold_uncertainty_score":0.9997238},"labels":[],"label_agreement":null},{"id":"W4404405312","doi":"10.48550/arxiv.2411.07258","title":"A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new $β$-arrestin inhibitor","year":2024,"lang":"en","type":"preprint","venue":"arXiv (Cornell University)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Région Normandie; Réseau québécois de recherche sur la douleur; Canadian Institutes of Health Research; European Commission; Université de Sherbrooke","keywords":"Terminal (telecommunication); Receptor; Peptide; Chemistry; Cell biology; Internal medicine; Endocrinology; Computer science; Biology; Biochemistry; Medicine; Telecommunications","score_opus":0.03479421421752468,"score_gpt":0.1912179056809754,"score_spread":0.15642369146345073,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404405312","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995638,0.00061076676,0.0012148003,0.00023209708,0.0011349594,0.00056021166,0.00016447714,0.000034067296,0.0004105943],"genre_scores_gemma":[0.99101365,0.00015156013,0.00033367917,0.00015454783,0.0008233399,0.000004046134,0.00015495784,0.000050719224,0.0073134773],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981297,0.00024080716,0.00028609278,0.00092818163,0.00012639836,0.00028881113],"domain_scores_gemma":[0.99830085,0.00004999623,0.0003122541,0.0010410249,0.00012132757,0.00017451751],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00018931672,0.00038117694,0.000316472,0.00004424817,0.00014294714,0.00008371466,0.0011183824,0.00047791304,0.00043775715],"category_scores_gemma":[0.00018277961,0.00027307824,0.00042975668,0.00019558884,0.0001733974,0.000005933531,0.0021576737,0.000641733,0.00004731672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000348687,0.00006728907,0.00055214367,0.00007517977,0.0003486651,0.000045997163,0.0003342018,0.003418019,0.9808792,0.00043619162,0.01300386,0.0004906037],"study_design_scores_gemma":[0.0010206643,0.00018744421,0.00020220397,0.00092048576,0.0005492616,0.000011308415,0.00048364594,0.0033136436,0.9699577,0.0095485775,0.013103933,0.0007011439],"about_ca_topic_score_codex":0.00085979106,"about_ca_topic_score_gemma":0.00019145606,"teacher_disagreement_score":0.0109214755,"about_ca_system_score_codex":0.000050041002,"about_ca_system_score_gemma":0.0008348809,"threshold_uncertainty_score":0.99997216},"labels":[],"label_agreement":null},{"id":"W4404432450","doi":"10.1038/s41467-024-54103-6","title":"A non-canonical mechanism of GPCR activation","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"National Institute of General Medical Sciences; Chemistry, Engineering and Medicine for Human Health, Stanford University; U.S. Department of Health and Human Services; National Institutes of Health; National Science Foundation","keywords":"G protein-coupled receptor; Allosteric regulation; Intracellular; Mutagenesis; Computational biology; Mechanism (biology); Function (biology); Drug discovery; G protein; Receptor; Signal transduction; Chemistry; Cell biology; Biology; Bioinformatics; Biochemistry; Mutation; Physics; Gene","score_opus":0.013382220394401238,"score_gpt":0.2954731890793676,"score_spread":0.28209096868496636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404432450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7269133,0.050416157,0.1597058,0.009675115,0.0023033808,0.0015234379,0.00018892503,0.00024304407,0.04903088],"genre_scores_gemma":[0.9923313,0.0005692466,0.006406964,0.00013825115,0.00008219333,0.000022536742,0.00020645373,0.00001501149,0.00022799653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951035,0.000033002034,0.00014077577,0.00014469285,0.00008689178,0.000084305524],"domain_scores_gemma":[0.9990782,0.000030830775,0.00003526625,0.0007409327,0.000085433676,0.000029332157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015648111,0.00007212819,0.00007707084,0.000045923734,0.00006770579,0.000019756313,0.00041649846,0.00027277425,0.00004552221],"category_scores_gemma":[0.000044838267,0.00006629126,0.00007143922,0.00012904128,0.000036510915,0.000004365034,0.00018008587,0.00031028304,0.0000080814725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000542136,0.000027736985,0.0000105014105,0.000010838667,0.000033909488,1.2659763e-7,0.00003701673,0.000004801297,0.9114833,0.08537929,0.00189842,0.0011086668],"study_design_scores_gemma":[0.000093487295,0.00007552474,0.000067358014,0.000048826616,0.000017818746,0.000003848711,0.00005111945,0.0015024024,0.8709777,0.0015904239,0.12547216,0.0000993107],"about_ca_topic_score_codex":0.000009627324,"about_ca_topic_score_gemma":0.000021818067,"teacher_disagreement_score":0.26541808,"about_ca_system_score_codex":0.000010955917,"about_ca_system_score_gemma":0.00009216038,"threshold_uncertainty_score":0.2703279},"labels":[],"label_agreement":null},{"id":"W4404538676","doi":"10.1016/j.jcjd.2024.09.025","title":"Unveiling Gaps in hESCβ-cell Function: Combining Single-cell Electrophysiology and scRNA-Seq","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Diabetes","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Alberta Hospital Edmonton","funders":"","keywords":"Medicine; Electrophysiology; Function (biology); Computational biology; Cell biology; Physiology; Biology","score_opus":0.006283156630060206,"score_gpt":0.1846508214508357,"score_spread":0.17836766482077548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404538676","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.974041,0.024683546,0.0001347743,0.000085587766,0.0005298313,0.000039141498,0.000003839899,0.0000028405816,0.00047942824],"genre_scores_gemma":[0.9989555,0.00007754151,0.00024588787,0.00021177862,0.00029172673,0.0000013494214,0.000009217168,0.000021596801,0.00018543817],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991592,0.0000516565,0.00024339429,0.00017433299,0.000055973658,0.0003154271],"domain_scores_gemma":[0.9995357,0.000025031615,0.00006666048,0.00007819299,0.000055675202,0.00023873123],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021804868,0.0001191583,0.00017264995,0.00018989043,0.000062487,0.00007853333,0.00009751708,0.00011925497,0.000093599934],"category_scores_gemma":[0.000029825116,0.00011299556,0.0000723685,0.0001139553,0.000045368455,0.000010124428,0.000012071922,0.00021374972,0.0000044704443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000044742133,0.000010338112,0.0016570251,0.000042102558,0.000023001016,0.00001679157,0.00005287161,0.00011946126,0.99602824,0.00006813214,0.0005774042,0.0014001335],"study_design_scores_gemma":[0.0007593699,0.0024480952,0.00090540695,0.00024697988,0.000051321418,0.000021153928,0.000301142,0.00046110785,0.97015756,0.0013241817,0.022980433,0.0003432599],"about_ca_topic_score_codex":0.00005770415,"about_ca_topic_score_gemma":0.00035577768,"teacher_disagreement_score":0.025870716,"about_ca_system_score_codex":0.000038003112,"about_ca_system_score_gemma":0.00038247654,"threshold_uncertainty_score":0.46078253},"labels":[],"label_agreement":null},{"id":"W4404623434","doi":"10.1021/acsomega.4c07071","title":"A High-Throughput Method for Screening Peptide Activators of G-Protein-Coupled Receptors","year":2024,"lang":"en","type":"article","venue":"ACS Omega","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Receptor; High-throughput screening; G protein-coupled receptor; Peptide; Throughput; Chemistry; Computational biology; Computer science; Biochemistry; Biology; Telecommunications","score_opus":0.01450543753523547,"score_gpt":0.2837908894849703,"score_spread":0.2692854519497348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404623434","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5648239,0.0009234851,0.4332204,0.00014925025,0.0004237636,0.00032069263,0.00002606808,0.000032601114,0.00007981101],"genre_scores_gemma":[0.8505913,0.00005413838,0.14669304,0.00007083317,0.00042818167,0.00009201015,0.00010692599,0.000057279656,0.0019062883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99882287,0.000046255616,0.000277708,0.0004323268,0.00014918661,0.00027162867],"domain_scores_gemma":[0.9994378,0.000056369903,0.00008358558,0.0002679088,0.00008601135,0.000068301575],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00046304273,0.00018499942,0.00023671385,0.0000741741,0.000073141826,0.000040831463,0.00018905036,0.00018778627,0.00004252711],"category_scores_gemma":[0.00013091177,0.00016701003,0.00019221946,0.00016651017,0.000030966392,0.00001012331,0.000085964595,0.00010223577,0.0000042366764],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009077105,0.00001661389,0.000008582139,0.0000871716,0.00015264434,0.0000012129557,0.00006290231,0.00013388532,0.9849732,0.0023814314,0.001678121,0.010413466],"study_design_scores_gemma":[0.0003253616,0.00031574903,0.0000054442653,0.00008601536,0.000032711792,0.0000034081938,0.00011450458,0.0007737274,0.9278978,0.0009922688,0.06926044,0.00019256171],"about_ca_topic_score_codex":0.00009792212,"about_ca_topic_score_gemma":0.0000063225966,"teacher_disagreement_score":0.28652734,"about_ca_system_score_codex":0.000014565165,"about_ca_system_score_gemma":0.00006931629,"threshold_uncertainty_score":0.68104714},"labels":[],"label_agreement":null},{"id":"W4404646564","doi":"10.1186/s12964-024-01931-0","title":"The cell adhesion molecule CD44 acts as a modulator of 5-HT7 receptor functions","year":2024,"lang":"en","type":"article","venue":"Cell Communication and Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"G protein-coupled receptor; Transactivation; Förster resonance energy transfer; Chemistry; Receptor; Cell biology; Agonist; Signal transduction; Biophysics; Biology; Transcription factor; Biochemistry","score_opus":0.00856106623885731,"score_gpt":0.23284517816914768,"score_spread":0.22428411193029038,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404646564","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9588764,0.029416386,0.0063165273,0.00020424537,0.00018146043,0.00018908316,0.000008020472,0.000028562568,0.0047793514],"genre_scores_gemma":[0.9923224,0.0031693736,0.00097007427,0.000067760055,0.000055929835,0.000018747682,0.00008239414,0.000023395181,0.003289952],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916565,0.00013368209,0.00023711233,0.00020860495,0.00011370621,0.00014126368],"domain_scores_gemma":[0.99921787,0.00008647438,0.000077688506,0.0004672885,0.000085184714,0.00006547893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037215147,0.00011697754,0.00009911764,0.00003708912,0.00032827904,0.00011991512,0.00023653945,0.00010959971,0.0000852447],"category_scores_gemma":[0.000032213375,0.00009180699,0.00008663821,0.000104951345,0.00006632905,0.000010732598,0.00013870839,0.00014213809,0.000018985174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000024192814,0.000024981504,0.000008438954,0.000037386042,0.000016055126,2.0032392e-7,0.00016882739,0.000113020156,0.9967924,0.0009932993,0.0006902931,0.0011309118],"study_design_scores_gemma":[0.00014297295,0.00011257126,0.0000028819927,0.00005158631,0.000019207746,0.0000018562747,0.0005944691,0.0010487143,0.92776394,0.00026831595,0.069886595,0.00010691065],"about_ca_topic_score_codex":0.000016478996,"about_ca_topic_score_gemma":0.000003089124,"teacher_disagreement_score":0.0691963,"about_ca_system_score_codex":0.000009623858,"about_ca_system_score_gemma":0.000052499705,"threshold_uncertainty_score":0.37437806},"labels":[],"label_agreement":null},{"id":"W4404874621","doi":"10.1093/ijnp/pyae060","title":"Combination of Haloperidol With UNC9994, β-arrestin-Biased Analog of Aripiprazole, Ameliorates Schizophrenia-Related Phenotypes Induced by NMDAR Deficit in Mice","year":2024,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Aripiprazole; Haloperidol; Partial agonist; Pharmacology; Dopamine receptor D2; Prefrontal cortex; Typical antipsychotic; Schizophrenia (object-oriented programming); Agonist; NMDA receptor; Dopamine; Psychology; Antipsychotic; Open field; Dopamine transporter; Atypical antipsychotic; Neuroscience; Medicine; Internal medicine; Receptor; Psychiatry; Dopaminergic; Cognition","score_opus":0.009284110535505033,"score_gpt":0.2711820577896552,"score_spread":0.26189794725415017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404874621","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960468,0.001206794,0.0003835595,0.00078848586,0.0013185731,0.000112033915,0.000019843534,0.0000044202734,0.00011951706],"genre_scores_gemma":[0.9990257,0.00039923805,0.0001627926,0.00021515621,0.0001232204,0.0000034189577,0.000017887265,0.00002112899,0.000031477826],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986546,0.0001632579,0.00061227113,0.00016921085,0.00028010184,0.0001205826],"domain_scores_gemma":[0.9989466,0.00010003227,0.00043720542,0.00008278805,0.00039417163,0.00003922059],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040343503,0.00013457779,0.00021033651,0.0002112685,0.000020706004,0.000021451719,0.00048133754,0.00008354506,0.00009419006],"category_scores_gemma":[0.00007087759,0.0000946987,0.000087153334,0.00023495579,0.000089030196,0.000015735359,0.00004651761,0.000290967,0.0000020812365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017994033,0.0001551484,0.00018735214,0.000013204594,0.00026951052,0.00003547683,0.00008825994,0.0015101953,0.99284154,0.00021568044,0.0005610254,0.0023231783],"study_design_scores_gemma":[0.0029382373,0.0012776817,0.0012940918,0.00013436467,0.00007936968,0.00017326506,0.00008701132,0.0011923921,0.9911755,0.0004516554,0.0010602336,0.00013624308],"about_ca_topic_score_codex":0.00003043364,"about_ca_topic_score_gemma":0.000007473421,"teacher_disagreement_score":0.002978907,"about_ca_system_score_codex":0.000019593264,"about_ca_system_score_gemma":0.00014815854,"threshold_uncertainty_score":0.3861701},"labels":[],"label_agreement":null},{"id":"W4405239409","doi":"10.1039/9781837672059-00031","title":"Combinatorial Behavioural Phenotyping of Mouse Models of Schizophrenia","year":2024,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Schizophrenia (object-oriented programming); Psychology; Neuroscience; Psychiatry","score_opus":0.02080335100714973,"score_gpt":0.22685892058135723,"score_spread":0.2060555695742075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405239409","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09600916,0.008707958,0.010785465,0.000030335834,0.0038386295,0.00084547576,0.0005924437,0.00007298043,0.87911755],"genre_scores_gemma":[0.70613205,0.00031536186,0.0010634454,0.00001465964,0.00039063493,0.0000052477935,0.00029741682,0.00011477171,0.2916664],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989195,0.0000066132425,0.000416138,0.00032742036,0.00019500624,0.00013531664],"domain_scores_gemma":[0.9993042,0.0000053388253,0.00018547682,0.0003163231,0.00013637976,0.000052306856],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010036817,0.00024834182,0.0003703623,0.00007578425,0.00001962189,0.000010732067,0.00019789134,0.00047605703,0.0003183582],"category_scores_gemma":[0.0000044208205,0.00022910675,0.00029452884,0.000013223226,0.000062607025,0.0000023431903,0.00016489688,0.00016745232,0.000007403416],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094670846,0.00001385988,5.244343e-7,0.00007777989,0.00012348504,0.0000012115552,0.000012678752,0.000057599806,0.42126906,0.5776524,0.0001894502,0.00050726655],"study_design_scores_gemma":[0.0005516258,0.00025226455,1.0698536e-7,0.00018107836,0.00015486048,0.0000034864124,0.000013945356,0.0004677083,0.87222,0.12292409,0.0028687695,0.00036210177],"about_ca_topic_score_codex":0.000034173056,"about_ca_topic_score_gemma":0.000006521205,"teacher_disagreement_score":0.6101229,"about_ca_system_score_codex":0.000010211003,"about_ca_system_score_gemma":0.00008004341,"threshold_uncertainty_score":0.9342702},"labels":[],"label_agreement":null},{"id":"W4405499104","doi":"10.1103/prxlife.2.043019","title":"Mpemba-Like Sensory Withdrawal Effect","year":2024,"lang":"en","type":"article","venue":"PRX Life","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Materials Research; Banff International Research Station for Mathematical Innovation and Discovery; University of North Carolina at Chapel Hill; National Science Foundation","keywords":"Sensory system; Psychology; Cognitive psychology","score_opus":0.006286502857811232,"score_gpt":0.24147863260661395,"score_spread":0.23519212974880271,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405499104","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9861483,0.004889244,0.004453485,0.00014220593,0.0012078802,0.0001571486,0.00001055655,0.00007345641,0.0029177417],"genre_scores_gemma":[0.99516237,0.000089606154,0.00038424454,0.00039613486,0.000806254,0.0000178898,0.00004121416,0.000030759584,0.0030715116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992471,0.000052633746,0.000113080474,0.0002916801,0.00010851624,0.00018699738],"domain_scores_gemma":[0.9996691,0.000017495731,0.000016253534,0.00017815985,0.000019678213,0.00009935777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020137869,0.00012509213,0.00010646717,0.000029080707,0.000050025028,0.0000580931,0.000091001646,0.00011095536,0.0001951506],"category_scores_gemma":[0.00004789342,0.00010254579,0.000100507576,0.000055316825,0.000022121994,0.000002617315,0.00005389348,0.00009211849,0.00014680269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003419232,0.00000905802,0.00018615225,0.000062312654,0.00006773355,0.000013625009,0.00003957656,0.000031504496,0.9876904,0.00027399432,0.008109419,0.0034820312],"study_design_scores_gemma":[0.00020224928,0.00032662615,0.000049074162,0.00003376862,0.00002542734,0.000021038695,0.000021924488,0.0005642759,0.7671914,0.00008547849,0.23128122,0.00019752842],"about_ca_topic_score_codex":0.0000071671952,"about_ca_topic_score_gemma":0.0000021908459,"teacher_disagreement_score":0.2231718,"about_ca_system_score_codex":0.0000067716237,"about_ca_system_score_gemma":0.00005869176,"threshold_uncertainty_score":0.4181696},"labels":[],"label_agreement":null},{"id":"W4405635648","doi":"10.1016/j.nsa.2024.105351","title":"The negative allosteric modulator of GABAA receptor, L655,708, increased dopamine neuronal activity 24 hours but not immediately after injection","year":2024,"lang":"en","type":"article","venue":"Neuroscience Applied","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"GABAA receptor; Allosteric modulator; Allosteric regulation; Dopamine; Chemistry; Neuroscience; Pharmacology; Dopamine receptor; Receptor; Medicine; Psychology; Biochemistry","score_opus":0.011946351499562904,"score_gpt":0.23413027451015667,"score_spread":0.22218392301059375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405635648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965005,0.000080913094,0.001462739,0.000102554164,0.0013655568,0.0002792096,0.00004410499,0.000029031162,0.00013541087],"genre_scores_gemma":[0.9988927,0.00010976163,0.00011839995,0.00030349963,0.00023612638,0.00008431482,0.000009298369,0.000028851951,0.00021702208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984369,0.000076497396,0.00021794594,0.00059971906,0.00035014766,0.00031875345],"domain_scores_gemma":[0.99938923,0.00006433426,0.00009917552,0.00029774426,0.000049581697,0.00009991251],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003011995,0.00020409263,0.00015380872,0.000058417132,0.00016121019,0.00011027025,0.00028500176,0.00010092844,0.000023168983],"category_scores_gemma":[0.00009841349,0.00015277433,0.00010178903,0.00029653142,0.00024660982,0.00001713638,0.00015727906,0.00018978896,0.000010234342],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003525301,0.00003487738,0.000039435963,0.000012588432,0.000006319424,0.0000022500653,0.000035296518,0.0000930739,0.99424624,0.00006781915,0.00010959317,0.004999958],"study_design_scores_gemma":[0.0002046472,0.0003584058,0.005198651,0.00001082603,0.000011680599,0.000008416917,0.000041926258,0.0010041166,0.99101263,0.000051612915,0.0019328046,0.00016427171],"about_ca_topic_score_codex":0.000032846307,"about_ca_topic_score_gemma":0.0000071403288,"teacher_disagreement_score":0.005159215,"about_ca_system_score_codex":0.000019669867,"about_ca_system_score_gemma":0.00011395759,"threshold_uncertainty_score":0.6229957},"labels":[],"label_agreement":null},{"id":"W4405675148","doi":"10.1101/2024.12.17.628075","title":"AlphaFold prediction and analysis of Adhesion-family G protein coupled receptor (aGPCR) structures","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Adhesion; Computational biology; Chemistry; Biology","score_opus":0.008874230971024605,"score_gpt":0.21432825059738997,"score_spread":0.20545401962636536,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405675148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895297,0.006508646,0.001554224,0.000036115354,0.00073412934,0.0006632945,0.0008798719,0.00008976435,0.0000042495867],"genre_scores_gemma":[0.99391395,0.0007588433,0.0046133725,0.000049631817,0.0004086812,0.00012470262,0.000012410813,0.00010207328,0.000016339087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997438,0.00011150912,0.0006209883,0.0011273632,0.0003601902,0.00034192146],"domain_scores_gemma":[0.9981697,0.000014693078,0.00037826528,0.00087995664,0.00036527126,0.00019208221],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004668653,0.0004986338,0.00067787344,0.0004229574,0.00009172419,0.00012417392,0.0003235737,0.0008027312,0.00008215074],"category_scores_gemma":[0.00011533369,0.0004896938,0.00032560006,0.0005573803,0.00010253189,0.0000067241717,0.0006309403,0.00044312177,0.0000049021464],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006738996,0.0000394994,0.00076885545,0.0003815244,0.001684493,0.000004067252,0.000006901896,0.00017729794,0.99617857,0.00048140337,0.00020590484,0.000004078634],"study_design_scores_gemma":[0.00025214234,0.00015192834,0.008626713,0.0002353207,0.0011132439,8.447168e-9,0.000006089986,0.0026157983,0.9851124,0.000013458123,0.0014025326,0.00047031252],"about_ca_topic_score_codex":0.000054598782,"about_ca_topic_score_gemma":0.0000026246046,"teacher_disagreement_score":0.011066132,"about_ca_system_score_codex":0.00004455052,"about_ca_system_score_gemma":0.00031600308,"threshold_uncertainty_score":0.99975544},"labels":[],"label_agreement":null},{"id":"W4405695727","doi":"10.1016/j.pharmthera.2024.108788","title":"Non-canonical signaling initiated by hormone-responsive G protein-coupled receptors from subcellular compartments","year":2024,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Receptor; G protein-coupled receptor; Non canonical; Signal transduction; Cell biology; Hormone; Hormone receptor; Chemistry; Biology; Internal medicine; Endocrinology; Biochemistry; Medicine","score_opus":0.06249043893659233,"score_gpt":0.3633521660185275,"score_spread":0.30086172708193515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405695727","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012712998,0.98227763,0.00061193854,0.000058455793,0.001886299,0.0019147686,0.0004217976,0.00007336765,0.00004275051],"genre_scores_gemma":[0.0040860926,0.9877978,0.00030418864,0.0010081459,0.0010211882,0.0005836894,0.0041684653,0.0002787278,0.00075172447],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9959895,0.0006164496,0.0010464458,0.0012366724,0.00032368486,0.00078726525],"domain_scores_gemma":[0.9985461,0.000102078186,0.00049341004,0.00045607434,0.00015016331,0.0002521801],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004414332,0.0010255635,0.001679624,0.00015760772,0.00019346905,0.00010197411,0.0007819941,0.0012276882,0.0006753606],"category_scores_gemma":[0.0000064698843,0.00088426186,0.00079722545,0.00030242966,0.00018554444,0.000007891978,0.00032970202,0.0010538716,0.00031629336],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024632932,0.00021711452,5.9835116e-7,0.0006234969,0.005518404,0.000059456564,0.00006260838,0.0000059127146,0.96618956,0.000004747932,0.008727739,0.018344054],"study_design_scores_gemma":[0.0007894279,0.00044545042,4.124688e-8,0.0006061526,0.005590693,0.000011469564,0.000022459157,0.00017085786,0.15960975,0.00003877677,0.8319422,0.0007726946],"about_ca_topic_score_codex":0.000021316288,"about_ca_topic_score_gemma":0.0000017002197,"teacher_disagreement_score":0.8232145,"about_ca_system_score_codex":0.00014108252,"about_ca_system_score_gemma":0.0006584847,"threshold_uncertainty_score":0.9993608},"labels":[],"label_agreement":null},{"id":"W4406002323","doi":"10.1038/s41573-024-01083-3","title":"Functional dynamics of G protein-coupled receptors reveal new routes for drug discovery","year":2025,"lang":"en","type":"review","venue":"Nature Reviews Drug Discovery","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences","keywords":"Drug discovery; G protein-coupled receptor; Computational biology; Drug; Receptor; Pharmacology; Chemistry; Bioinformatics; Medicine; Biology; Biochemistry","score_opus":0.013628298758519813,"score_gpt":0.2885396217707293,"score_spread":0.27491132301220944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406002323","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00003155252,0.98149574,0.010522762,0.00009503546,0.0022481633,0.004700469,0.0007062298,0.000018759669,0.00018126152],"genre_scores_gemma":[0.000014982267,0.9142011,0.0025237298,0.00012197952,0.0015380777,0.0006759017,0.007674024,0.00011778096,0.07313242],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9956941,0.00035188854,0.0017063943,0.001295896,0.00040778227,0.0005439649],"domain_scores_gemma":[0.99701196,0.00018241044,0.0014428324,0.0010368596,0.00017836234,0.00014755785],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0010889617,0.0010354129,0.0031423965,0.00022330266,0.00014222006,0.00016681265,0.0008272148,0.001271907,0.00005944394],"category_scores_gemma":[0.0007880764,0.0007775111,0.0029517752,0.00048183987,0.00007729531,0.000055456807,0.00034038708,0.00097358966,0.000008708572],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019803175,0.00022510471,0.0000030223116,0.09241216,0.0009709229,0.0000021225414,0.000024718782,0.000015852167,0.001794827,0.004853298,0.14309561,0.75640434],"study_design_scores_gemma":[0.00038164476,0.000077839526,1.948523e-7,0.025675587,0.000934274,0.0000066160437,0.000020472022,0.0000067189994,0.0015051664,0.00035620335,0.9702768,0.0007585189],"about_ca_topic_score_codex":0.000026248608,"about_ca_topic_score_gemma":0.00007294156,"teacher_disagreement_score":0.82718116,"about_ca_system_score_codex":0.00018367427,"about_ca_system_score_gemma":0.0016247013,"threshold_uncertainty_score":0.9994676},"labels":[],"label_agreement":null},{"id":"W4406016732","doi":"10.1038/s41467-024-55466-6","title":"Generic residue numbering of the GAIN domain of adhesion GPCRs","year":2025,"lang":"en","type":"article","venue":"Nature Communications","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"Novo Nordisk Fonden; Stiftung Charité; Universität Leipzig; Novo Nordisk; Deutsche Forschungsgemeinschaft; H. Lundbeck A/S; Lundbeckfonden; Friedrich-Alexander-Universität Erlangen-Nürnberg","keywords":"Numbering; Residue (chemistry); G protein-coupled receptor; Computer science; Computational biology; Chemistry; Biology; Biochemistry; Receptor; Algorithm","score_opus":0.01040240673857263,"score_gpt":0.2786203329747887,"score_spread":0.2682179262362161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406016732","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9685768,0.017627683,0.0025927527,0.0012779967,0.00025858398,0.0002513734,0.000025535941,0.000008726288,0.009380552],"genre_scores_gemma":[0.99147296,0.0005198406,0.0075739557,0.00013529522,0.000015809652,0.000009029981,0.00002998633,0.000005531682,0.00023758684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995147,0.00010805686,0.00016213249,0.00008734634,0.00006422053,0.00006356175],"domain_scores_gemma":[0.99863756,0.00002974235,0.00009197311,0.0011362389,0.000093195085,0.000011311616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017421493,0.0000548784,0.00008146598,0.000025816566,0.0000987813,0.0000035683565,0.00070127106,0.00017388602,0.000008278007],"category_scores_gemma":[0.000085946944,0.000042198008,0.00007208106,0.00017862217,0.00006964407,0.000001302865,0.00038420127,0.00018293032,3.265162e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006969598,0.000026960523,0.000940901,0.000010779079,0.000020893183,1.6617806e-8,0.000032457745,0.000055584096,0.9858089,0.011453561,0.001214728,0.000428263],"study_design_scores_gemma":[0.00011689934,0.000015722122,0.0015072405,0.000045182223,0.000012039416,5.9668866e-7,0.000107183965,0.0000708196,0.9716178,0.0008624155,0.02559933,0.00004476959],"about_ca_topic_score_codex":0.00001770417,"about_ca_topic_score_gemma":0.000112991394,"teacher_disagreement_score":0.024384603,"about_ca_system_score_codex":0.0000070209385,"about_ca_system_score_gemma":0.000059609585,"threshold_uncertainty_score":0.17207849},"labels":[],"label_agreement":null},{"id":"W4406087143","doi":"10.1038/s44320-024-00080-3","title":"Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs","year":2025,"lang":"en","type":"erratum","venue":"Molecular Systems Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; University of Regina; Princess Margaret Cancer Centre; Institute for Research in Immunology and Cancer; University Health Network; University of Toronto","funders":"","keywords":"Biology; G protein-coupled receptor; Computational biology; Bioinformatics; Genetics; Receptor","score_opus":0.022944040843938366,"score_gpt":0.31393005221528436,"score_spread":0.290986011371346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406087143","genre_codex":"methods","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010100418,0.016488086,0.795491,0.000496867,0.1484411,0.01913133,0.00031185243,0.00029880324,0.009240557],"genre_scores_gemma":[0.24234053,0.0001150102,0.002446099,0.00036998617,0.0062519824,0.009734014,0.008142327,0.0003531579,0.7302469],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99441564,0.0011102426,0.0020202647,0.001505497,0.00024567885,0.0007026603],"domain_scores_gemma":[0.99656814,0.00005747766,0.0014658696,0.0011749894,0.0005772296,0.00015628578],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0016433304,0.0007764492,0.0015477164,0.00034094806,0.0003465025,0.00015922767,0.0006908603,0.0025675907,0.000025901512],"category_scores_gemma":[0.001017171,0.00072155375,0.00079355005,0.00020489463,0.00009018167,0.000006115129,0.00026980301,0.000850658,0.000022086326],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095810195,0.00006394508,0.0000023180778,0.014986084,0.00068911276,0.000014126828,0.000027213178,0.00003996167,0.8672535,0.0015131467,0.11514569,0.00016913525],"study_design_scores_gemma":[0.0014885401,0.003629644,0.0000013043326,0.036053307,0.00051511644,0.00013608768,0.0006689982,0.0030109065,0.14621899,0.0006198718,0.8055413,0.0021159363],"about_ca_topic_score_codex":0.00012571008,"about_ca_topic_score_gemma":0.000022243614,"teacher_disagreement_score":0.79304487,"about_ca_system_score_codex":0.00016000523,"about_ca_system_score_gemma":0.000406347,"threshold_uncertainty_score":0.9995236},"labels":[],"label_agreement":null},{"id":"W4406099205","doi":"10.1001/jamaneurol.2024.4519","title":"An Acetylcholine M<sub>1</sub> Receptor–Positive Allosteric Modulator (TAK-071) in Parkinson Disease With Cognitive Impairment","year":2025,"lang":"en","type":"article","venue":"JAMA Neurology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Cognitive impairment; Parkinson's disease; Allosteric modulator; Cognition; Disease; Medicine; Neuroscience; Allosteric regulation; Acetylcholine; Psychology; Receptor; Pharmacology; Internal medicine","score_opus":0.004537686724188424,"score_gpt":0.22671919165232937,"score_spread":0.22218150492814095,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406099205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99539274,0.00028179717,0.002391928,0.00096258806,0.00024534034,0.0005295733,0.00006868608,0.000025630688,0.000101696045],"genre_scores_gemma":[0.99391603,0.00020207425,0.00014767617,0.0049742335,0.00020887954,0.0001275383,0.00035306983,0.000037850146,0.000032639124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99803495,0.00032803812,0.0002782044,0.0007902303,0.00013202103,0.00043658033],"domain_scores_gemma":[0.9992267,0.000035427965,0.00010468307,0.00032905594,0.00011686177,0.00018728011],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001918751,0.0002837752,0.00027119135,0.00013898687,0.00008245043,0.000042467003,0.00020520085,0.00029858275,0.000028321647],"category_scores_gemma":[0.000058155223,0.00026127172,0.00007927061,0.00021881668,0.000097305696,0.00001551556,0.000121300865,0.000312535,0.000009950899],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0056482474,0.00040450066,0.013843854,0.000023367349,0.000073486415,0.000076393924,0.00008400623,0.00066189375,0.97245437,0.00006755704,0.00023851858,0.0064237905],"study_design_scores_gemma":[0.00405445,0.0036656703,0.08346679,0.00007671676,0.00006892622,0.000021204389,0.00008508376,0.0022731521,0.90181696,0.00012902284,0.0038744654,0.00046757617],"about_ca_topic_score_codex":0.000014295951,"about_ca_topic_score_gemma":0.000046516492,"teacher_disagreement_score":0.07063744,"about_ca_system_score_codex":0.000020776532,"about_ca_system_score_gemma":0.0001302493,"threshold_uncertainty_score":0.99998397},"labels":[],"label_agreement":null},{"id":"W4406150626","doi":"10.1038/s41589-024-01812-0","title":"Molecular mechanisms of inverse agonism via κ-opioid receptor–G protein complexes","year":2025,"lang":"en","type":"article","venue":"Nature Chemical Biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Center for Complementary and Integrative Health; National Institute of General Medical Sciences; National Institute on Drug Abuse; U.S. Department of Health and Human Services; National Institutes of Health; University of California, San Francisco; Canada Excellence Research Chairs, Government of Canada; University of Southern California","keywords":"Agonism; G protein-coupled receptor; Chemistry; Opioid; Opioid receptor; Inverse agonist; Computational biology; Receptor; Pharmacology; Neuroscience; Medicine; Biochemistry; Biology; Antagonist","score_opus":0.004206913001146756,"score_gpt":0.24239450570748536,"score_spread":0.2381875927063386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406150626","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9414742,0.0015539698,0.054527562,0.00033918774,0.00046615486,0.0004001517,0.00004741942,0.000032932312,0.0011583959],"genre_scores_gemma":[0.98694915,0.000033220214,0.011258804,0.0010184239,0.000094026094,0.000040140738,0.0004277957,0.000019760177,0.00015870958],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986547,0.00008329011,0.0003252834,0.00052054325,0.00009774382,0.00031843953],"domain_scores_gemma":[0.9992514,0.000018964096,0.00012377834,0.00037877588,0.0001499202,0.00007715864],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017417895,0.0002385012,0.00033096276,0.0000766738,0.000044403798,0.000007985291,0.00039552388,0.0011988305,0.00013183278],"category_scores_gemma":[0.00017081718,0.00021429268,0.0001893571,0.00017599005,0.00016453357,0.0000024937146,0.00023195098,0.00041743816,0.000007619032],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009395372,0.00006937674,0.000019574913,0.00004279438,0.00008582297,0.0000010724577,0.000007039125,0.0000025611907,0.9634868,0.034192726,0.000671115,0.0013271681],"study_design_scores_gemma":[0.00046064454,0.00015621589,0.0000030026877,0.000031649226,0.000017762679,0.0000026343266,0.000015592299,0.000028267295,0.95139134,0.031826716,0.015870554,0.00019563515],"about_ca_topic_score_codex":0.000011447275,"about_ca_topic_score_gemma":0.000002032005,"teacher_disagreement_score":0.045474894,"about_ca_system_score_codex":0.000021348615,"about_ca_system_score_gemma":0.00008030522,"threshold_uncertainty_score":0.9246479},"labels":[],"label_agreement":null},{"id":"W4406236695","doi":"10.1016/j.phrs.2025.107597","title":"A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor","year":2025,"lang":"en","type":"article","venue":"Pharmacological Research","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Région Normandie; Fonds de Recherche du Québec - Santé; Réseau québécois de recherche sur la douleur; Canadian Institutes of Health Research; European Commission; Université de Sherbrooke","keywords":"Peptide; Chemistry; Terminal (telecommunication); Receptor; Vasopressin; Neuropeptide; Vasopressin receptor; Pharmacology; Cell biology; Antagonist; Endocrinology; Biochemistry; Biology; Computer science","score_opus":0.06226957035471797,"score_gpt":0.38299179210960216,"score_spread":0.3207222217548842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406236695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99357575,0.0009357383,0.00020889068,0.0030261555,0.0003822801,0.0007865549,0.00003020592,0.00001389581,0.0010404981],"genre_scores_gemma":[0.9916066,0.00019139776,0.0005121749,0.00086896884,0.000675474,0.00013254456,0.000030648902,0.000014662469,0.0059675095],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974057,0.0008833378,0.0003095107,0.00047037282,0.00047721236,0.0004538731],"domain_scores_gemma":[0.99873286,0.00038371186,0.00008524759,0.00036410202,0.00024737336,0.0001867279],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001017578,0.00017118601,0.00019598649,0.000035941597,0.0003208682,0.00007220958,0.0009877646,0.00020333518,0.0022349046],"category_scores_gemma":[0.0021045832,0.00009237271,0.00015887004,0.00035528792,0.00032636893,0.00000556108,0.0008643871,0.00059602794,0.00003184827],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006401187,0.00011531463,0.00046566452,0.000009543279,0.000079797166,0.000004644714,0.00006793109,0.000014240117,0.9176177,0.000062610474,0.07616078,0.0047616865],"study_design_scores_gemma":[0.0008762953,0.00021031877,0.00056398776,0.000069433394,0.000031865315,0.0000017904086,0.0001210714,0.00014480723,0.944175,0.0007153012,0.05298803,0.00010207156],"about_ca_topic_score_codex":0.0002642604,"about_ca_topic_score_gemma":0.000025807454,"teacher_disagreement_score":0.026557364,"about_ca_system_score_codex":0.000034135028,"about_ca_system_score_gemma":0.00073001406,"threshold_uncertainty_score":0.9986772},"labels":[],"label_agreement":null},{"id":"W4406331962","doi":"10.1111/all.16460","title":"Allergic Reactivity and Memory Occur Independently of Sequential Switching Through <scp>IgG1</scp>","year":2025,"lang":"en","type":"article","venue":"Allergy","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; Population Health Research Institute; McMaster University Medical Centre","funders":"European Social Fund; Instituto de Salud Carlos III; Canadian Institutes of Health Research; University of Illinois at Urbana-Champaign; Food Allergy Canada; McMaster University; Canadian Allergy, Asthma and Immunology Foundation","keywords":"Reactivity (psychology); Immunology; Medicine","score_opus":0.01053397754536986,"score_gpt":0.2514418109451276,"score_spread":0.24090783339975771,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406331962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9796699,0.0016021744,0.009212984,0.000042997974,0.00031546908,0.00010500655,0.0000066829534,0.000013281144,0.009031496],"genre_scores_gemma":[0.9969888,0.00064979127,0.0007683189,0.00022856513,0.00011051909,0.000009001466,0.000033961067,0.000015551772,0.001195544],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99899465,0.000068182206,0.0002238197,0.00035945134,0.00013616259,0.00021771784],"domain_scores_gemma":[0.9994863,0.000034288118,0.00011108758,0.00026375728,0.000058804417,0.000045724762],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020026308,0.00015907036,0.00020138656,0.000042099826,0.00008342529,0.000023035172,0.00016398577,0.00020309012,0.00002346919],"category_scores_gemma":[0.00008036926,0.00015699498,0.000093609146,0.00007346918,0.000038477727,0.000010313515,0.00021028434,0.00012230386,0.0000015569644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021621296,0.0000472527,0.000119840115,0.00002552583,0.00019875809,0.00000397892,0.00019908838,0.00007761145,0.9948659,0.0014987449,0.00094165286,0.00200002],"study_design_scores_gemma":[0.00061210035,0.00010879427,0.00046292396,0.000031813084,0.000017861665,0.000008502259,0.0003970289,0.00007586464,0.96243805,0.001494431,0.034274183,0.00007845815],"about_ca_topic_score_codex":0.000261284,"about_ca_topic_score_gemma":0.00013616121,"teacher_disagreement_score":0.03333253,"about_ca_system_score_codex":0.000010016751,"about_ca_system_score_gemma":0.000082586106,"threshold_uncertainty_score":0.64020693},"labels":[],"label_agreement":null},{"id":"W4406514172","doi":"10.1101/2025.01.15.633249","title":"Cognitive enrichment preserves retrosplenial parvalbumin density and cognitive function in female 5xFAD mice","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Parvalbumin; Retrosplenial cortex; Cognition; Function (biology); Psychology; Neuroscience; Cognitive psychology; Biology; Cell biology; Hippocampus","score_opus":0.01152129142089968,"score_gpt":0.2313294943429193,"score_spread":0.21980820292201964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406514172","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989758,0.003103127,0.005132363,0.000028764758,0.0007332,0.0008746917,0.00030177826,0.000047400914,0.000020683909],"genre_scores_gemma":[0.997809,0.000586853,0.00072551984,0.00019002045,0.00039364665,0.00019479624,0.000008212206,0.00004782157,0.000044110406],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973738,0.00024486435,0.00044015492,0.0012492309,0.00024335331,0.00044856538],"domain_scores_gemma":[0.99862796,0.000060978102,0.00027426795,0.00039476986,0.00048343762,0.00015857317],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00053387333,0.0004963801,0.0004829903,0.00017596401,0.00013737984,0.00012659842,0.00021479746,0.0007418771,0.000030752453],"category_scores_gemma":[0.00038414742,0.00056186784,0.00013107702,0.00021508295,0.000106277716,0.000013972965,0.0007357865,0.0005428773,0.000006221282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004818824,0.00015041715,0.030168256,0.00030049725,0.00029176657,0.000019094716,0.00001945962,0.000011877625,0.9683739,0.00010097906,0.00006888202,0.000012991285],"study_design_scores_gemma":[0.0011133286,0.0002092359,0.0968908,0.00070711004,0.00026120833,2.3157549e-8,0.000032353768,0.00009390698,0.89966875,0.0000050100966,0.00041895238,0.0005992954],"about_ca_topic_score_codex":0.000106704676,"about_ca_topic_score_gemma":0.000041154974,"teacher_disagreement_score":0.06870512,"about_ca_system_score_codex":0.00005195916,"about_ca_system_score_gemma":0.0003845731,"threshold_uncertainty_score":0.99968326},"labels":[],"label_agreement":null},{"id":"W4406520848","doi":"10.1016/s0029-7437(06)71868-7","title":"10.1016/s0029-7437(06)71868-7","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine; Fetus; First trimester; Obstetrics; Pregnancy; Biology; Genetics","score_opus":0.004762390398388728,"score_gpt":0.17950698975697357,"score_spread":0.17474459935858486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406520848","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.01040966,0.00019497536,0.0000397633,0.000074090894,4.3874516e-7,0.00014320375,0.000015133209,0.000037461392,0.98908526],"genre_scores_gemma":[0.0015052573,0.0000016969312,0.00047383847,0.00007906337,0.00031613943,0.000015711332,0.00008712419,0.000029080431,0.9974921],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99917203,0.00002999013,0.00014460273,0.00029180187,0.00010971305,0.00025183178],"domain_scores_gemma":[0.99952096,0.0000050018707,0.000022641558,0.00028318667,0.000037204944,0.00013101095],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00011591798,0.00014016827,0.00012172425,0.000026963015,0.000071486276,0.00003123097,0.00018692273,0.00011547581,0.9918601],"category_scores_gemma":[0.000018124212,0.00013577972,0.00008559376,0.00007067501,0.00001720188,0.0000025778013,0.000047154062,0.000060670252,0.9503719],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006451755,0.000031868218,9.260505e-8,0.0000033992153,0.000023786048,0.0000016285351,0.0000055159903,0.00012118061,0.19067152,0.0000012561129,0.7423256,0.06674962],"study_design_scores_gemma":[0.00017517801,0.00022538706,0.0000021584078,0.000007040355,0.000008635032,0.000007277723,0.0000010811177,0.0000586715,0.09471679,0.000007696607,0.9046149,0.00017514368],"about_ca_topic_score_codex":0.0000070486635,"about_ca_topic_score_gemma":1.3080877e-7,"teacher_disagreement_score":0.16228932,"about_ca_system_score_codex":0.000008489734,"about_ca_system_score_gemma":0.000024086083,"threshold_uncertainty_score":0.55369365},"labels":[],"label_agreement":null},{"id":"W4406522453","doi":"10.1016/s0029-7437(06)71974-7","title":"10.1016/s0029-7437(06)71974-7","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Venlafaxine; Gabapentin; Psychology; Medicine; Psychiatry; Antidepressant; Anxiety","score_opus":0.004861837364133517,"score_gpt":0.18018340230494734,"score_spread":0.17532156494081383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406522453","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.010701703,0.00019555698,0.000036444857,0.00007214458,4.2999528e-7,0.00014149072,0.000015702926,0.00003730838,0.9887992],"genre_scores_gemma":[0.0014058569,0.0000014568085,0.00047638285,0.00007585013,0.00030688554,0.000015956088,0.00008927278,0.000028841785,0.9975995],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991712,0.000029926685,0.00014490684,0.00029119616,0.00011046529,0.00025231298],"domain_scores_gemma":[0.9995184,0.0000051011743,0.0000232737,0.0002845661,0.00003741871,0.00013121923],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000115611365,0.00014033582,0.00012215954,0.000027292968,0.00006998067,0.000030279432,0.00018940128,0.00011556715,0.9920492],"category_scores_gemma":[0.000017863116,0.00013587174,0.00008289491,0.000072817886,0.0000172587,0.000002588258,0.000047232475,0.000060371734,0.9512295],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006845561,0.00003239357,9.0488484e-8,0.0000035015933,0.000024469913,0.0000016741226,0.0000059816034,0.0001466954,0.17216147,0.0000012619896,0.7605951,0.066958934],"study_design_scores_gemma":[0.00017424769,0.00022880985,0.000002116601,0.0000072247253,0.000008687532,0.000007352599,0.0000011561709,0.000065533844,0.08497256,0.000007658987,0.91434747,0.00017715732],"about_ca_topic_score_codex":0.000006789776,"about_ca_topic_score_gemma":1.3041968e-7,"teacher_disagreement_score":0.15375243,"about_ca_system_score_codex":0.000008500877,"about_ca_system_score_gemma":0.000024260165,"threshold_uncertainty_score":0.55406886},"labels":[],"label_agreement":null},{"id":"W4406578428","doi":"10.1016/s1544-8800(05)70431-0","title":"10.1016/s1544-8800(05)70431-0","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Cardiotoxicity; Medicine; Drug; Internal medicine; Pharmacology; Chemotherapy","score_opus":0.003998925988990048,"score_gpt":0.1716824987419522,"score_spread":0.16768357275296217,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406578428","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012338427,0.00016949557,0.000033391967,0.00008699249,0.0000040294653,0.00014342138,0.0000139828135,0.000032701973,0.98717755],"genre_scores_gemma":[0.0018033052,0.0000017096405,0.00040938583,0.00008618667,0.00030577573,0.00001579119,0.00007084991,0.000029175295,0.9972778],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991689,0.000029901656,0.00014431585,0.00029179375,0.000110589346,0.0002545222],"domain_scores_gemma":[0.9995173,0.0000050653375,0.000023196926,0.00028458325,0.00003756297,0.00013228336],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00011200782,0.00014042045,0.00012277353,0.00002728623,0.000069241054,0.000030486277,0.00019058162,0.00011522377,0.98995537],"category_scores_gemma":[0.000017188871,0.00013568727,0.0000830263,0.000072166666,0.00001742711,0.000002653371,0.000049213224,0.000059574606,0.9280105],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012372022,0.000043101798,7.647054e-8,0.000004546241,0.000031641182,0.0000037964694,0.000007718287,0.00016604288,0.2627393,0.0000016186826,0.27828363,0.45859483],"study_design_scores_gemma":[0.00017946349,0.00028012219,0.0000029871842,0.0000067001897,0.000008518164,0.00000910201,0.0000010912734,0.00004952047,0.10387965,0.000007680581,0.89540213,0.00017304154],"about_ca_topic_score_codex":0.00001261153,"about_ca_topic_score_gemma":2.1966913e-7,"teacher_disagreement_score":0.61711854,"about_ca_system_score_codex":0.000008708144,"about_ca_system_score_gemma":0.000025514582,"threshold_uncertainty_score":0.5533166},"labels":[],"label_agreement":null},{"id":"W4406580166","doi":"10.1016/s1541-9800(06)70889-4","title":"10.1016/s1541-9800(06)70889-4","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Medicine","score_opus":0.003910097945246142,"score_gpt":0.17078262795048177,"score_spread":0.16687253000523564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406580166","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011869358,0.00019973812,0.00003438995,0.000083149425,0.0000026859057,0.00014303585,0.000015287258,0.000032432526,0.98761994],"genre_scores_gemma":[0.0019992096,0.0000018376478,0.00038755455,0.0000869818,0.0003016633,0.000015978674,0.00009405604,0.000029205583,0.9970835],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99916327,0.00003078355,0.00014560703,0.00029234716,0.00011213621,0.0002558688],"domain_scores_gemma":[0.99951434,0.0000051866155,0.000022868422,0.0002848447,0.00003818152,0.00013455485],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001183884,0.00014082275,0.00012296808,0.00002757767,0.00006961868,0.000030540716,0.0001899649,0.000116274634,0.9904827],"category_scores_gemma":[0.000018897515,0.0001362252,0.00008323624,0.00007396597,0.000017487864,0.0000026574369,0.000047469013,0.000060524377,0.9480508],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011171534,0.00005115403,1.4370329e-7,0.0000056557647,0.000038619444,0.0000036433478,0.000009899953,0.0002114362,0.33626217,0.0000019611387,0.3626088,0.3006948],"study_design_scores_gemma":[0.00017932485,0.00022358165,0.0000022960342,0.000007024096,0.000008570923,0.0000069218972,0.0000011660505,0.000055777946,0.1010528,0.000008027894,0.8982798,0.00017471417],"about_ca_topic_score_codex":0.0000070410333,"about_ca_topic_score_gemma":1.3062512e-7,"teacher_disagreement_score":0.535671,"about_ca_system_score_codex":0.000008656084,"about_ca_system_score_gemma":0.00002605613,"threshold_uncertainty_score":0.5555102},"labels":[],"label_agreement":null},{"id":"W4406811653","doi":"10.1146/annurev-pharmtox-061724-080727","title":"G Protein–Coupled Receptor Heteromers in Brain: Functional and Therapeutic Importance in Neuropsychiatric Disorders","year":2025,"lang":"en","type":"review","venue":"The Annual Review of Pharmacology and Toxicology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"G protein-coupled receptor; Context (archaeology); Receptor; Neuroscience; Computational biology; Drug discovery; Drug development; Function (biology); Biology; Functional selectivity; Drug; Chemistry; Bioinformatics; Pharmacology; Cell biology; Biochemistry","score_opus":0.012767950945206883,"score_gpt":0.3171485547011193,"score_spread":0.3043806037559124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406811653","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0034819588,0.9930177,0.000015592805,0.0012553666,0.00039366918,0.0017253378,0.00003181702,0.0000042052857,0.00007434947],"genre_scores_gemma":[0.0012146379,0.9952542,0.000026973461,0.0026848002,0.000102919155,0.00044209295,0.000064090695,0.000021464763,0.00018877456],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974451,0.000915771,0.0007324752,0.0005245354,0.000077384975,0.00030471367],"domain_scores_gemma":[0.99915177,0.00021356987,0.00036903218,0.00018248697,0.00003962401,0.000043536773],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00089993706,0.00033943728,0.0011622511,0.00017309953,0.000057593643,0.000004529496,0.0002594356,0.0003486809,0.00018330466],"category_scores_gemma":[0.00010867366,0.00024104398,0.00018711666,0.00035382377,0.0002250133,0.00000528188,0.00018027752,0.00044715276,0.0000018993693],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028301252,0.00038133023,0.00014577464,0.09329579,0.0005020052,0.0000104218325,0.00008107416,0.000005237226,0.010739947,0.0009077375,0.0042258403,0.8894218],"study_design_scores_gemma":[0.0008908977,0.00063517445,0.00008067449,0.006730453,0.00037061702,0.00003405662,0.000031316602,0.000006094913,0.00009095363,0.00020279994,0.990582,0.0003449744],"about_ca_topic_score_codex":0.0000059048925,"about_ca_topic_score_gemma":0.000036226993,"teacher_disagreement_score":0.98635614,"about_ca_system_score_codex":0.000018033988,"about_ca_system_score_gemma":0.00024532416,"threshold_uncertainty_score":0.9829488},"labels":[],"label_agreement":null},{"id":"W4407119808","doi":"10.26508/lsa.202503226","title":"Unconventional receptor functions and location-biased signaling of the lactate GPCR in the nucleus","year":2025,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research; Université de Montréal","keywords":"G protein-coupled receptor; Nucleus; Biology; Cell biology; Chromatin; Signal transduction; Computational biology; Gene; Genetics","score_opus":0.011315985400000068,"score_gpt":0.25328903718033785,"score_spread":0.2419730517803378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407119808","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948233,0.0004891938,0.0025347315,0.0011657701,0.0003145396,0.00014445788,0.000006765802,0.0000026835125,0.00051857444],"genre_scores_gemma":[0.9982827,0.000042607262,0.00041986298,0.0006610188,0.000037700647,0.000013568529,0.0000035930898,0.0000023518407,0.0005366423],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99932736,0.000043783835,0.0001432638,0.00020230228,0.00016066054,0.00012263292],"domain_scores_gemma":[0.9995802,0.00002611002,0.000061441,0.00019494949,0.00011424363,0.000023023378],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056211284,0.000056346504,0.00005522128,0.000022680058,0.00019605306,0.00003433623,0.00032837276,0.000031346313,0.000023778015],"category_scores_gemma":[0.00026579155,0.000036464615,0.000027004842,0.00061254203,0.00026862381,0.0000090681815,0.00005754866,0.00006119003,0.000002119093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012030934,0.00002360251,0.0034027686,0.000011455504,0.0000058995943,5.7392246e-8,0.00009244564,0.0010034287,0.99197006,0.0024712367,0.0004194991,0.00058749336],"study_design_scores_gemma":[0.00064617454,0.000105837906,0.023464588,0.00022432145,0.000021281305,0.000002016553,0.002335103,0.0023258606,0.9494078,0.0018335799,0.01942316,0.00021023401],"about_ca_topic_score_codex":0.00001990512,"about_ca_topic_score_gemma":0.00001977668,"teacher_disagreement_score":0.04256224,"about_ca_system_score_codex":0.000007999797,"about_ca_system_score_gemma":0.0002752247,"threshold_uncertainty_score":0.15079014},"labels":[],"label_agreement":null},{"id":"W4407257284","doi":"10.7554/elife.99373.2","title":"Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration","year":2025,"lang":"en","type":"preprint","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"Daiichi Sankyo Europe; Moonshot Research and Development Program; School of Medicine, New York University; National Institute of General Medical Sciences; Japan Society for the Promotion of Science; Wellcome Trust; National Cancer Institute; Japan Science and Technology Agency; Daiichi Sankyo Foundation of Life Science; National Institutes of Health; Biotechnology and Biological Sciences Research Council; LEO Fondet; Uehara Memorial Foundation","keywords":"Cell biology; Chemokine receptor; Endosome; G protein-coupled receptor; CCR1; Chemotaxis; C-C chemokine receptor type 7; CCL21; Biology; C-C chemokine receptor type 6; Signal transduction; Receptor; Chemistry; Chemokine; Biochemistry; Intracellular","score_opus":0.01641026564224464,"score_gpt":0.252572163661834,"score_spread":0.23616189801958937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407257284","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8300356,0.0037833995,0.1561068,0.00080516684,0.004543778,0.0012502124,0.00040951496,0.00017358111,0.0028919147],"genre_scores_gemma":[0.97020465,0.0012427308,0.017558627,0.0005163511,0.000748339,0.000097238444,0.0022926447,0.000068563066,0.0072708656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974593,0.00012314982,0.0005136951,0.0009489518,0.00039587863,0.0005590486],"domain_scores_gemma":[0.9986815,0.000017396276,0.00030522945,0.0006460788,0.00017477227,0.00017503611],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026204108,0.00050358736,0.0004343611,0.00011155331,0.00015890636,0.000118715616,0.00046773104,0.0008093874,0.0003512468],"category_scores_gemma":[0.000053370797,0.00052262313,0.00036931335,0.00009717027,0.00003540309,0.00000556683,0.0006150478,0.00043667183,0.000020943946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007023217,0.0000666102,0.0000344924,0.00016231502,0.000111691814,0.000002793739,0.00009039972,0.0017419178,0.9926351,0.0006624794,0.0034615158,0.00096045976],"study_design_scores_gemma":[0.0004950798,0.00013256558,0.000051094386,0.00015655275,0.000067532834,0.0000022582801,0.00009104667,0.0008291252,0.97988135,0.0010157096,0.016756246,0.0005214219],"about_ca_topic_score_codex":0.000063787076,"about_ca_topic_score_gemma":0.000026722919,"teacher_disagreement_score":0.14016901,"about_ca_system_score_codex":0.00007333754,"about_ca_system_score_gemma":0.00035142136,"threshold_uncertainty_score":0.99972254},"labels":[],"label_agreement":null},{"id":"W4407377947","doi":"10.1101/2025.02.10.637554","title":"Pallidal prototypic neuron and astrocyte activities regulate flexible reward-seeking behaviors","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Kootenay Association for Science & Technology","funders":"Korea Advanced Institute of Science and Technology; Institute for Information and Communications Technology Promotion; Electronics and Telecommunications Research Institute; Soonchunhyang University; National Research Foundation; National Research Foundation of Korea; Ministry of Science and ICT, South Korea; Mayo Clinic","keywords":"Astrocyte; Neuroscience; Neuron; Psychology; Reward system; Central nervous system","score_opus":0.009603024310649652,"score_gpt":0.224757005698847,"score_spread":0.21515398138819733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407377947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99117136,0.0013783446,0.005150657,0.00005138283,0.0008664923,0.0010658525,0.0001402251,0.00015658545,0.00001909017],"genre_scores_gemma":[0.9932107,0.00050706405,0.005118843,0.00011686685,0.00048138882,0.00032955452,0.0000022593204,0.000103439575,0.00012993385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973174,0.00014993585,0.0004446519,0.0012438082,0.00027125582,0.00057300355],"domain_scores_gemma":[0.99829376,0.000015832777,0.00031493427,0.0009936898,0.00018166995,0.00020009185],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00037191535,0.00060724677,0.00050728733,0.0001899272,0.00023240143,0.00025012568,0.00042709065,0.0007360481,0.000028813956],"category_scores_gemma":[0.00006507705,0.0006741184,0.00018497124,0.00016366898,0.00011298202,0.000014937125,0.00083861017,0.00059953297,0.0000031349246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010387745,0.000050464438,0.0027093554,0.00032538443,0.000104309074,0.000011710083,0.000006894152,0.00010077856,0.9963258,0.00017113276,0.00007631425,0.000013994388],"study_design_scores_gemma":[0.0004180545,0.00016705727,0.0077750534,0.00039154434,0.00011416761,4.688428e-8,0.000005631283,0.0001170775,0.9832389,0.0000033710107,0.0071030497,0.00066607556],"about_ca_topic_score_codex":0.00003087073,"about_ca_topic_score_gemma":0.0000032379594,"teacher_disagreement_score":0.013086914,"about_ca_system_score_codex":0.000056382498,"about_ca_system_score_gemma":0.00045314137,"threshold_uncertainty_score":0.999571},"labels":[],"label_agreement":null},{"id":"W4407387346","doi":"10.1093/ijnp/pyae059.374","title":"AMPA RECEPTOR DENSITY DETERMINES LOCAL AND GLOBAL FUNCTIONAL CONNECTIVITY","year":2025,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"AMPA receptor; Functional connectivity; Neuroscience; Receptor; Biology; Glutamate receptor; Genetics","score_opus":0.009925397917147475,"score_gpt":0.29102078986616065,"score_spread":0.2810953919490132,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407387346","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96713156,0.00032654873,0.024886906,0.0027369016,0.0046188347,0.000055934062,0.0000074907402,0.0000035046694,0.00023233364],"genre_scores_gemma":[0.995576,0.00025928058,0.00015693325,0.0032845188,0.00056146766,0.0000021741932,0.0000030748893,0.000005083346,0.00015146786],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992206,0.00012501334,0.00023990465,0.00014921642,0.00016037741,0.00010488276],"domain_scores_gemma":[0.99931395,0.00006357866,0.00016379778,0.00007375561,0.00033772973,0.00004717198],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027688424,0.00009808959,0.00011974142,0.00004498741,0.00006713197,0.000028507313,0.00030794684,0.0000604858,0.00010756349],"category_scores_gemma":[0.00008816234,0.00007201383,0.00008838477,0.00005768987,0.00012414574,0.0000075315706,0.00012684346,0.000141227,0.0000029762498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013799462,0.00006176683,0.0023710716,0.000002503177,0.00022293921,0.000019262248,0.000008483285,0.0001954288,0.9732742,0.0004933818,0.010042831,0.011928185],"study_design_scores_gemma":[0.007367536,0.0012060348,0.07584123,0.00005664961,0.00021858257,0.0027660353,0.00020110379,0.0010260436,0.75463945,0.006135472,0.15013269,0.00040915675],"about_ca_topic_score_codex":0.0000050838435,"about_ca_topic_score_gemma":0.0000071079044,"teacher_disagreement_score":0.21863472,"about_ca_system_score_codex":0.000028338203,"about_ca_system_score_gemma":0.00008912792,"threshold_uncertainty_score":0.29366386},"labels":[],"label_agreement":null},{"id":"W4407426323","doi":"10.3389/fmolb.2025.1567250","title":"Editorial: Omics in endocrinology: from biomarker discovery to targeting therapeutic strategies","year":2025,"lang":"en","type":"editorial","venue":"Frontiers in Molecular Biosciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Omics; Biomarker discovery; Biomarker; Computational biology; Medicine; Bioinformatics; Biology; Proteomics; Biochemistry","score_opus":0.0050963318581478635,"score_gpt":0.25437345224267144,"score_spread":0.24927712038452357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407426323","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008974116,0.0053433776,0.059891947,0.000087229426,0.92490125,0.00039949146,0.00021429558,0.000016891232,0.0001713965],"genre_scores_gemma":[0.02157637,0.0026486218,0.022752954,0.00031516314,0.9504214,0.00018576505,0.0015572892,0.0000940306,0.00044838715],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9963931,0.0002702813,0.0005856761,0.0013358293,0.0006532062,0.0007619294],"domain_scores_gemma":[0.99905807,0.00006994608,0.00018837367,0.0004815001,0.00011049254,0.00009159095],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006447072,0.00049300096,0.00059160806,0.00051199546,0.00009541543,0.00036361627,0.0011755103,0.0011045572,0.0000062877393],"category_scores_gemma":[0.0006182151,0.000475934,0.0001812522,0.00060440856,0.00019906221,0.000028830713,0.00039189347,0.00054580363,0.0000018177703],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009390099,0.00003805503,0.00023009941,0.000019234647,0.000048031237,0.000013913737,0.000053255917,0.00021890785,0.37817568,0.00003501276,0.6202854,0.0007885029],"study_design_scores_gemma":[0.00060551165,0.00020842164,0.000031020078,0.00016980739,0.000032863445,2.0587441e-7,0.0014079582,0.000113658454,0.11887772,0.002473101,0.8753268,0.0007528929],"about_ca_topic_score_codex":0.0005790361,"about_ca_topic_score_gemma":0.00015859707,"teacher_disagreement_score":0.25929797,"about_ca_system_score_codex":0.00011735851,"about_ca_system_score_gemma":0.0010459269,"threshold_uncertainty_score":0.9997692},"labels":[],"label_agreement":null},{"id":"W4407431005","doi":"10.1016/j.bpj.2024.11.632","title":"BPS2025 - Waltz in the membrane: Unveiling the spatiotemporal dynamics of M1 muscarinic receptors and G proteins","year":2025,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Waltz; Muscarinic acetylcholine receptor; Dynamics (music); Biophysics; Chemistry; Receptor; Biology; Physics; Biochemistry","score_opus":0.007103351606494617,"score_gpt":0.24332922435341994,"score_spread":0.23622587274692533,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407431005","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953069,0.00014139948,0.002716302,0.0011547174,0.00022070274,0.00018173465,0.000003735894,0.000002265411,0.00027224643],"genre_scores_gemma":[0.9989777,0.00017592193,0.00035511612,0.00016446417,0.00019601357,0.0000070257,0.0000094575935,0.000006775722,0.00010749793],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991599,0.00014746867,0.00025179834,0.00014715374,0.00014228327,0.00015141396],"domain_scores_gemma":[0.9996093,0.000035417037,0.00010542945,0.0001698701,0.000050290022,0.000029705227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00044262662,0.00010453704,0.00013629178,0.000038839582,0.00012853794,0.000046445413,0.00026110938,0.00008884103,0.000011574133],"category_scores_gemma":[0.000060157745,0.000059226444,0.000097196425,0.00015920069,0.000094266274,0.000004834676,0.00007448109,0.00025267675,4.9856135e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070028684,0.0000833757,0.000664561,0.000026286622,0.000047904236,0.0000024383226,0.00016236103,0.00008183483,0.9842877,0.0037469626,0.000111823625,0.010714742],"study_design_scores_gemma":[0.001075281,0.0005313928,0.0032012025,0.00015838938,0.000060480783,0.000035976256,0.0016544333,0.005318593,0.9816028,0.0024567053,0.0036464457,0.000258313],"about_ca_topic_score_codex":0.000039260867,"about_ca_topic_score_gemma":0.000036917605,"teacher_disagreement_score":0.01045643,"about_ca_system_score_codex":0.000014538689,"about_ca_system_score_gemma":0.0000784328,"threshold_uncertainty_score":0.24151842},"labels":[],"label_agreement":null},{"id":"W4407479266","doi":"10.1016/j.bpj.2024.11.635","title":"BPS2025 - Quantifying GPCR-G protein binding affinity by analysis of steady-state fluorescence fluctuations with two-color image cumulant analysis","year":2025,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Cumulant; Steady state (chemistry); Fluorescence; Biological system; Chemistry; Biology; Mathematics; Statistics; Physics; Optics; Physical chemistry","score_opus":0.013121895454346437,"score_gpt":0.28596138669792637,"score_spread":0.2728394912435799,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407479266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8682028,0.00004017107,0.131344,0.00006313386,0.00004366215,0.00013517235,0.000090866335,0.00000834332,0.00007185765],"genre_scores_gemma":[0.9923525,0.000043621825,0.007108077,0.00002718141,0.00005631411,0.000012580757,0.00017204252,0.000012264159,0.0002154075],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842924,0.00014245258,0.0004469207,0.0003701417,0.0003070949,0.00030413293],"domain_scores_gemma":[0.99897283,0.000031896056,0.0003159568,0.0002892916,0.0002685539,0.00012148802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031930694,0.00021030163,0.00049284426,0.00045583266,0.000252143,0.00011361916,0.00028764986,0.00007888255,0.000059823145],"category_scores_gemma":[0.000055508575,0.00016450841,0.00046788898,0.0019863057,0.000104832114,0.000019639581,0.00008567816,0.00022143548,0.0000023631428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014825983,0.00014832002,0.0004986453,0.000013958128,0.0039898506,0.0000060562197,0.000046708537,0.0026861085,0.99167895,0.0002381103,0.00004635793,0.0004986553],"study_design_scores_gemma":[0.00048315435,0.00018565526,0.0006556554,0.000042377113,0.002378719,0.0000016971545,0.0001690868,0.015350892,0.9804341,0.00002721872,0.000072425064,0.0001990256],"about_ca_topic_score_codex":0.000064306674,"about_ca_topic_score_gemma":0.00004262864,"teacher_disagreement_score":0.12423592,"about_ca_system_score_codex":0.000034566445,"about_ca_system_score_gemma":0.00013452709,"threshold_uncertainty_score":0.6708458},"labels":[],"label_agreement":null},{"id":"W4407494307","doi":"10.1016/j.bpj.2024.11.2779","title":"BPS2025 - Quantifying GPCR-G protein binding affinity by analysis of steady-state fluorescence fluctuations with two-color image cumulant analysis","year":2025,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Cumulant; Fluorescence; Chemistry; Biological system; G protein-coupled receptor; Image (mathematics); Biophysics; Biology; Mathematics; Physics; Statistics; Computer science; Biochemistry; Artificial intelligence; Receptor; Optics","score_opus":0.013121895454346437,"score_gpt":0.28596138669792637,"score_spread":0.2728394912435799,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407494307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8682028,0.00004017107,0.131344,0.00006313386,0.00004366215,0.00013517235,0.000090866335,0.00000834332,0.00007185765],"genre_scores_gemma":[0.9923525,0.000043621825,0.007108077,0.00002718141,0.00005631411,0.000012580757,0.00017204252,0.000012264159,0.0002154075],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842924,0.00014245258,0.0004469207,0.0003701417,0.0003070949,0.00030413293],"domain_scores_gemma":[0.99897283,0.000031896056,0.0003159568,0.0002892916,0.0002685539,0.00012148802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031930694,0.00021030163,0.00049284426,0.00045583266,0.000252143,0.00011361916,0.00028764986,0.00007888255,0.000059823145],"category_scores_gemma":[0.000055508575,0.00016450841,0.00046788898,0.0019863057,0.000104832114,0.000019639581,0.00008567816,0.00022143548,0.0000023631428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014825983,0.00014832002,0.0004986453,0.000013958128,0.0039898506,0.0000060562197,0.000046708537,0.0026861085,0.99167895,0.0002381103,0.00004635793,0.0004986553],"study_design_scores_gemma":[0.00048315435,0.00018565526,0.0006556554,0.000042377113,0.002378719,0.0000016971545,0.0001690868,0.015350892,0.9804341,0.00002721872,0.000072425064,0.0001990256],"about_ca_topic_score_codex":0.000064306674,"about_ca_topic_score_gemma":0.00004262864,"teacher_disagreement_score":0.12423592,"about_ca_system_score_codex":0.000034566445,"about_ca_system_score_gemma":0.00013452709,"threshold_uncertainty_score":0.6708458},"labels":[],"label_agreement":null},{"id":"W4407545332","doi":"10.1080/21688370.2025.2465048","title":"β-arrestin 1 and integrin-linked kinase interact in epidermal keratinocytes and regulate cell motility","year":2025,"lang":"en","type":"article","venue":"Tissue Barriers","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; Children’s Health Research Institute; Lawson Health Research Institute","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cell biology; Integrin-linked kinase; Arrestin; Biology; Motility; Integrin; Epidermis (zoology); Signal transduction; Scaffold protein; Cell migration; G protein-coupled receptor; Cell; Protein kinase A; Kinase; Cyclin-dependent kinase 2; Anatomy; Biochemistry","score_opus":0.005208639251775729,"score_gpt":0.24933977597844198,"score_spread":0.24413113672666625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407545332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99563813,0.0020903714,0.0012633288,0.00015156121,0.00014815142,0.00016686223,0.000005958111,0.000009968267,0.00052565587],"genre_scores_gemma":[0.9972862,0.00011968017,0.0013452027,0.00016280227,0.000039089333,0.000011816732,0.000018100249,0.000010042196,0.0010070938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99911875,0.00008380157,0.00020717004,0.00035098277,0.000048396538,0.0001908766],"domain_scores_gemma":[0.9996163,0.000025565143,0.000040875788,0.00017948999,0.000027064783,0.00011065096],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023891957,0.0001455284,0.00016608828,0.00005652972,0.00006818955,0.00004018871,0.00008223162,0.00012777375,0.00007776135],"category_scores_gemma":[0.00018656347,0.00014087738,0.00002372856,0.00006527431,0.00007918821,0.000006229992,0.00011990545,0.00012580334,0.0000011699253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000081503546,0.000014294803,0.007828043,0.000059548147,0.000012831539,0.000012332308,0.00020464142,0.00008358409,0.9816387,0.00015745207,0.00025672102,0.009650314],"study_design_scores_gemma":[0.0007710499,0.00012878109,0.009863807,0.000071717805,0.000013798756,0.000006349046,0.0003786012,0.001276844,0.9793908,0.00046755568,0.0074478574,0.00018283543],"about_ca_topic_score_codex":0.000107079184,"about_ca_topic_score_gemma":0.000049586204,"teacher_disagreement_score":0.009467479,"about_ca_system_score_codex":0.0000118024755,"about_ca_system_score_gemma":0.00004865609,"threshold_uncertainty_score":0.5744813},"labels":[],"label_agreement":null},{"id":"W4407592364","doi":"10.1101/2025.02.10.637468","title":"Helix-8 and Carboxyl Terminal Tail Regulation of Proteinase Activated Receptor-4 (PAR4) signalling","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Intracellular; Phosphorylation; Arrestin; Cell biology; Receptor; Transmembrane domain; Signal transduction; G protein; Helix (gastropod); Cell signaling; Biology; Chemistry; Biochemistry","score_opus":0.009357324143448252,"score_gpt":0.21323796480134968,"score_spread":0.20388064065790143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407592364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99214476,0.0015268603,0.0047187586,0.000046153837,0.000459753,0.0008300155,0.00019486508,0.00006389026,0.000014935664],"genre_scores_gemma":[0.9908569,0.00039181972,0.008079997,0.0000455864,0.00038273356,0.00012452014,0.000005286014,0.00006775294,0.00004539639],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99758244,0.0001660993,0.0005914712,0.0009899683,0.00028465298,0.00038537796],"domain_scores_gemma":[0.99799955,0.00002215158,0.0005351276,0.0007574963,0.00051711797,0.00016857304],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004934544,0.0005008534,0.0005358809,0.00019793467,0.00013018618,0.00008596101,0.00034499238,0.0008083659,0.000051390176],"category_scores_gemma":[0.00017197501,0.0005480241,0.00015720044,0.00023286004,0.00010934331,0.00001237637,0.00048729312,0.00040750924,0.0000023517703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013028129,0.0000669935,0.000511964,0.0005540167,0.00015944427,0.000003805186,0.0000071917248,0.00018466625,0.9981125,0.00017392903,0.00007964817,0.000015546251],"study_design_scores_gemma":[0.0004358518,0.00014557505,0.0012245106,0.0006922914,0.00008783447,2.3693119e-8,0.0000051814764,0.00031131992,0.99455684,0.0000048700335,0.0020119369,0.00052376144],"about_ca_topic_score_codex":0.00006159476,"about_ca_topic_score_gemma":0.0000021264095,"teacher_disagreement_score":0.0035556701,"about_ca_system_score_codex":0.00005580885,"about_ca_system_score_gemma":0.00053026155,"threshold_uncertainty_score":0.99969715},"labels":[],"label_agreement":null},{"id":"W4407689967","doi":"10.1126/scisignal.adf6206","title":"Sustained Gα <sub>s</sub> signaling mediated by vasopressin type 2 receptors is ligand dependent but endocytosis and β-arrestin independent","year":2025,"lang":"en","type":"article","venue":"Science Signaling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"","keywords":"Endocytosis; Cell biology; Endosome; G protein-coupled receptor; Arrestin; Internalization; Receptor; Biology; G protein; Signal transduction; Vasopressin; Enzyme-linked receptor; Chemistry; Intracellular; Biochemistry; Endocrinology","score_opus":0.007136377732427779,"score_gpt":0.23827818598579997,"score_spread":0.2311418082533722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407689967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901273,0.0023522638,0.006018975,0.00016131962,0.0006923396,0.00032435328,0.000022313872,0.000047443453,0.00025365365],"genre_scores_gemma":[0.99791986,0.0003436031,0.0007013952,0.0005293842,0.00013200025,0.000023595532,0.000050807306,0.000031578762,0.0002678051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99688125,0.00010093973,0.00049196807,0.0010887615,0.00066182745,0.00077525165],"domain_scores_gemma":[0.99864984,0.0000886046,0.00019795286,0.0003851118,0.0003913898,0.00028707634],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001406226,0.00036009966,0.00031776473,0.00027167652,0.0006792521,0.00033282136,0.00057256967,0.00025461294,0.00006431725],"category_scores_gemma":[0.0005808223,0.00034658486,0.00008998773,0.0008113044,0.00034878275,0.000040517174,0.00051262975,0.00027270938,0.000009615645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007455623,0.00003788515,0.00076721894,0.000030107543,0.000046063953,0.000005855948,0.00015801913,0.00021018682,0.99430895,0.000063032996,0.00054694456,0.0037511545],"study_design_scores_gemma":[0.00064294663,0.00016381111,0.000033640103,0.00011362688,0.00004372644,0.0000064094224,0.00091679237,0.0005568544,0.9961402,0.00040569002,0.00059399946,0.00038230998],"about_ca_topic_score_codex":0.000051413208,"about_ca_topic_score_gemma":0.0000074675604,"teacher_disagreement_score":0.007792493,"about_ca_system_score_codex":0.00008890936,"about_ca_system_score_gemma":0.00056537107,"threshold_uncertainty_score":0.9998986},"labels":[],"label_agreement":null},{"id":"W4407766055","doi":"10.1021/acs.biochem.4c00492","title":"Role of the Palmitoyl Group and of the Amphipathic α Helix in the Membrane Binding of the C-Terminus of G-Protein Receptor Kinase 4α/β","year":2025,"lang":"en","type":"article","venue":"Biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Fonds de Recherche du Québec - Santé; Fondation des Maladies de l'Oeil","keywords":"Chemistry; Helix (gastropod); N-terminus; Amphiphile; Receptor; Biophysics; Cell biology; Stereochemistry; Biochemistry; Biology; Peptide sequence; Gene; Ecology","score_opus":0.0041749532482475505,"score_gpt":0.20549893167343278,"score_spread":0.20132397842518523,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407766055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99730325,0.001808411,0.00000923493,0.00014699611,0.000101104255,0.00028224627,0.00005798408,0.0000014058456,0.00028939458],"genre_scores_gemma":[0.9994904,0.00007354081,0.00006417025,0.0000457406,0.000042574316,0.000019507566,0.0000066885773,0.000009156732,0.00024822482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989216,0.00013975748,0.00037139805,0.00021661923,0.0002065048,0.00014412755],"domain_scores_gemma":[0.99888253,0.000034759043,0.0003214852,0.00068404403,0.000060296305,0.000016869428],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004482035,0.00014092847,0.00019991904,0.000019017003,0.00006851068,0.0000067732612,0.0006902791,0.00020001514,0.000015130378],"category_scores_gemma":[0.00018370558,0.00007158592,0.00018518214,0.00025260303,0.0002739564,0.0000022489014,0.00030704102,0.00015328365,7.8547416e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041457788,0.000058831,0.0017557642,0.00025360452,0.000028146223,1.2790441e-7,0.00014684342,0.000004948695,0.9970363,0.00013334579,0.000038613736,0.00050203747],"study_design_scores_gemma":[0.000310544,0.000035691442,0.0008916645,0.00035363476,0.000024183531,0.0000026713312,0.0006821104,0.000013403016,0.9971832,0.00013154456,0.0002998942,0.00007143505],"about_ca_topic_score_codex":0.00006592153,"about_ca_topic_score_gemma":0.000014703685,"teacher_disagreement_score":0.0021871733,"about_ca_system_score_codex":0.000009804914,"about_ca_system_score_gemma":0.00009961697,"threshold_uncertainty_score":0.2919189},"labels":[],"label_agreement":null},{"id":"W4407770155","doi":"10.1103/physreve.111.024408","title":"Ligand-induced receptor multimerization achieves specificity enhancement of kinetic proofreading without associated costs","year":2025,"lang":"en","type":"article","venue":"Physical review. E","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Proofreading; Ligand (biochemistry); Chemistry; Receptor; Biophysics; Cell biology; Computational biology; Biochemistry; Biology; Enzyme; Polymerase","score_opus":0.013376031300306257,"score_gpt":0.3153517200864268,"score_spread":0.3019756887861206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407770155","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99087113,0.002016603,0.0052865352,0.00009809274,0.00014209279,0.00050195266,0.0000064992278,0.0000114825725,0.0010656219],"genre_scores_gemma":[0.9965667,0.0022324002,0.00046834524,0.00017623052,0.00009850567,0.00004492261,0.00012188246,0.00001321846,0.00027775884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99901974,0.0000965568,0.00028480185,0.0002857178,0.00014859978,0.00016460015],"domain_scores_gemma":[0.9994254,0.000020083338,0.00017749869,0.0002096138,0.00012435127,0.000043024193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019050707,0.00015011594,0.00033398802,0.000022472104,0.000047387566,0.0000109732855,0.00013690641,0.00005626371,0.00003116171],"category_scores_gemma":[0.0002993964,0.00012984526,0.00012926654,0.00017949405,0.000022399547,0.000004112423,0.000062581894,0.00008020725,0.00001203897],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019714726,0.00018137887,0.00037665872,0.00016446157,0.00005447003,6.888719e-8,0.000014701774,0.000002249664,0.98749113,0.00038585346,0.00027546973,0.0110338135],"study_design_scores_gemma":[0.00022623148,0.00018008199,0.00035714183,0.0009643841,0.000053327713,8.654194e-8,0.000005365186,0.00034882646,0.9957362,0.000104478895,0.0018984821,0.00012538632],"about_ca_topic_score_codex":0.0000099302215,"about_ca_topic_score_gemma":0.0000019439024,"teacher_disagreement_score":0.010908428,"about_ca_system_score_codex":0.000031256295,"about_ca_system_score_gemma":0.000040820574,"threshold_uncertainty_score":0.5294936},"labels":[],"label_agreement":null},{"id":"W4408109575","doi":"10.1016/j.bpj.2025.02.027","title":"Flipping the switch: Illuminating inverted ligand activation of peptide-gated ion channels","year":2025,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; SGS (Canada); University of British Columbia","funders":"Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Michael Smith Health Research BC","keywords":"Ion channel; Chemistry; Peptide; Biophysics; Ligand (biochemistry); Receptor; Biology; Biochemistry","score_opus":0.012240425706998058,"score_gpt":0.2477371532659683,"score_spread":0.23549672755897022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408109575","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778154,0.00003566977,0.021167163,0.00033197555,0.00034383775,0.000078737045,0.0000010980997,0.000005050197,0.0002210668],"genre_scores_gemma":[0.998843,0.00003838919,0.00018003178,0.00017761638,0.00054667564,0.0000022204383,0.000008892432,0.0000082570195,0.00019489738],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929005,0.00006145998,0.00023099125,0.00013394485,0.00013584079,0.00014769801],"domain_scores_gemma":[0.9995072,0.000023256289,0.00015845378,0.00011736004,0.00015565834,0.000038056827],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021625469,0.00009838201,0.00012409186,0.000045051052,0.00018352106,0.000042340194,0.00015799078,0.000087113935,0.000011716692],"category_scores_gemma":[0.0001120146,0.00006795771,0.00011175201,0.00016909715,0.00004587794,0.000007162808,0.00006133747,0.00016265514,0.0000014220615],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000037762835,0.00003489924,0.000028908758,0.000010463972,0.000054829037,5.339384e-7,0.00008697113,0.00013570255,0.9944094,0.0002709176,0.00030311215,0.0046265223],"study_design_scores_gemma":[0.00028743132,0.0001108784,0.0001516592,0.000101829726,0.000015714471,0.0000053531376,0.00025679296,0.0024487516,0.9953212,0.0002604181,0.00096407236,0.000075891956],"about_ca_topic_score_codex":0.000008011596,"about_ca_topic_score_gemma":4.2526543e-7,"teacher_disagreement_score":0.021027617,"about_ca_system_score_codex":0.0000136641365,"about_ca_system_score_gemma":0.000053357595,"threshold_uncertainty_score":0.2771235},"labels":[],"label_agreement":null},{"id":"W4408244228","doi":"10.1038/s41586-025-08683-y","title":"Prohormone cleavage prediction uncovers a non-incretin anti-obesity peptide","year":2025,"lang":"en","type":"article","venue":"Nature","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Stanford Cardiovascular Institute, School of Medicine, Stanford University; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Stanford Maternal and Child Health Research Institute; Howard Hughes Medical Institute; Stanford Bio-X; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; Stanford Diabetes Research Center; National Institute of General Medical Sciences; American Heart Association","keywords":"Prohormone convertase; Peptide; Prohormone; Melanocortin; Proprotein Convertases; Proglucagon; Leptin; Incretin; Receptor; Glucose homeostasis; Chemistry; Peptide hormone; Glucagon-like peptide-1; Biology; Hormone; Biochemistry; Endocrinology; Insulin; Diabetes mellitus; Obesity","score_opus":0.0023331935363943962,"score_gpt":0.2219852714702794,"score_spread":0.21965207793388503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408244228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98714817,0.0009074419,0.003597888,0.00019339268,0.00052888924,0.00023852837,0.00003267565,0.000027667253,0.007325376],"genre_scores_gemma":[0.9954669,0.00015366804,0.000791068,0.00072869984,0.00023725937,0.000011063031,0.00014807768,0.000012015475,0.0024512599],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992275,0.00002941527,0.0001265342,0.000311777,0.00012473484,0.00017998618],"domain_scores_gemma":[0.99960876,0.0000056895747,0.000044518194,0.00023143737,0.000066913795,0.00004271247],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018240113,0.00012626276,0.000119782024,0.000043531218,0.00010219208,0.0000260793,0.0001444961,0.0010219017,0.000028062137],"category_scores_gemma":[0.00006614893,0.00011624894,0.00008709562,0.00013085426,0.00002156436,0.0000039993106,0.00007900787,0.00062663184,0.0000073095516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006175999,0.000033455883,0.0054299794,0.000025611263,0.000045823155,0.0000028687257,0.000017451452,0.00003352408,0.9519421,0.00020562815,0.041612856,0.0005889522],"study_design_scores_gemma":[0.00044421945,0.000117568954,0.008814561,0.00003973054,0.00002425938,0.0000031211723,0.000059434467,0.00011227504,0.9288886,0.00015976364,0.06121003,0.00012641834],"about_ca_topic_score_codex":0.000012215585,"about_ca_topic_score_gemma":0.000006894127,"teacher_disagreement_score":0.023053471,"about_ca_system_score_codex":0.000020814568,"about_ca_system_score_gemma":0.000067002016,"threshold_uncertainty_score":0.78818417},"labels":[],"label_agreement":null},{"id":"W4408290871","doi":"10.1152/ajpheart.00151.2025","title":"From signal to action: the roles of β<sub>1</sub>-adrenergic receptors in cardiac function and disease","year":2025,"lang":"en","type":"letter","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"B.C. Women's Hospital & Health Centre; Women's Health Research Institute; Dalhousie University","funders":"","keywords":"Action (physics); Adrenergic receptor; Receptor; Function (biology); Adrenergic; Disease; SIGNAL (programming language); Cardiology; Internal medicine; Medicine; Neuroscience; Biology; Cell biology; Physics; Computer science","score_opus":0.007282523375435421,"score_gpt":0.2202163039709647,"score_spread":0.21293378059552928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408290871","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900736,0.0020877498,0.000017946855,0.006782101,0.0008274939,0.00015695502,0.00004604072,0.0000040141845,0.0000040531963],"genre_scores_gemma":[0.96370435,0.0006828147,0.00004068351,0.032411955,0.0029794911,0.000018169532,0.0001232126,0.000028738754,0.000010596568],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99782145,0.00061372976,0.0005302398,0.00056293333,0.0001593395,0.0003123109],"domain_scores_gemma":[0.99871385,0.00012772702,0.00052240293,0.0003472471,0.00014383574,0.00014495978],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00024158918,0.00033923078,0.0009199812,0.00018143581,0.000092575676,0.000011872728,0.00021909524,0.00034008248,0.000023534885],"category_scores_gemma":[0.000042259573,0.00026406732,0.0003129312,0.000173128,0.00048109374,0.000010802706,0.00013126995,0.0007225232,0.0000013663688],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048679952,0.000027534274,0.0002499045,0.000042875345,0.00029955502,5.1965463e-7,0.00006233739,0.00024479037,0.9718763,0.0000072415364,0.024819486,0.001882616],"study_design_scores_gemma":[0.0019279413,0.0060820696,0.45069438,0.0006517802,0.0011363473,0.000033412965,0.0021162678,0.00007584186,0.30124864,0.009854285,0.22449371,0.0016853092],"about_ca_topic_score_codex":0.00003667981,"about_ca_topic_score_gemma":0.000005375094,"teacher_disagreement_score":0.6706277,"about_ca_system_score_codex":0.000024789135,"about_ca_system_score_gemma":0.00024023921,"threshold_uncertainty_score":0.99998116},"labels":[],"label_agreement":null},{"id":"W4408462533","doi":"10.1111/apha.70027","title":"Editorial related to the special issue: “Extrarenal functions of the renin‐angiotensin‐system”","year":2025,"lang":"en","type":"editorial","venue":"Acta Physiologica","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Receptor; Angiotensin II; Signal transduction; Angiotensin II receptor type 1; Angiotensin receptor; G protein-coupled receptor; Biology; Renin–angiotensin system; Pharmacology; Cell biology; Endocrinology; Biochemistry","score_opus":0.004724826080664671,"score_gpt":0.22548173801592786,"score_spread":0.2207569119352632,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408462533","genre_codex":"editorial","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"editorial","genre_consensus":"editorial","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017456352,0.000128252,0.000021326527,0.00041596,0.99436295,0.00047658308,0.0004523119,0.00002352885,0.0023734346],"genre_scores_gemma":[0.015019876,0.0000686628,0.00005197809,0.00006230309,0.97596145,0.00004533565,0.00072555925,0.000028082915,0.008036734],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977127,0.0002857836,0.00048557945,0.0006415131,0.0005369816,0.0003374626],"domain_scores_gemma":[0.99798685,0.00016253167,0.00035469464,0.0009773899,0.0004539594,0.000064547916],"candidate_categories":["research_integrity"],"consensus_categories":[],"category_scores_codex":[0.00034969702,0.0003687752,0.00046025624,0.000043465865,0.00037503516,0.000042264175,0.001032737,0.0013950781,0.00019350895],"category_scores_gemma":[0.00094406423,0.00020108266,0.00050738745,0.0002831837,0.00010859993,0.0000031510456,0.0005500545,0.0006992994,0.00003220296],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017126858,0.000024607323,5.079066e-7,0.000012555251,0.00014132187,2.8033253e-7,0.000025570323,0.00007701882,0.19931673,0.000024438066,0.7999481,0.0002575995],"study_design_scores_gemma":[0.00024952402,0.00034088115,0.000020273856,0.000107956555,0.00010823014,6.734338e-7,0.000051120907,0.000003742757,0.012889471,0.000055496705,0.98594165,0.00023100921],"about_ca_topic_score_codex":0.000055340624,"about_ca_topic_score_gemma":0.000016340584,"teacher_disagreement_score":0.18642727,"about_ca_system_score_codex":0.00004263576,"about_ca_system_score_gemma":0.00037220705,"threshold_uncertainty_score":0.9999013},"labels":[],"label_agreement":null},{"id":"W4408665468","doi":"10.1021/acsmedchemlett.4c00592","title":"Design, Synthesis, and Evaluation of a New Fluorescent Ligand for the M<sub>2</sub> Muscarinic Acetylcholine Receptor","year":2025,"lang":"en","type":"article","venue":"ACS Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Drug Research and Development","funders":"European Regional Development Fund; Nemzeti Kutatási Fejlesztési és Innovációs Hivatal; Xunta de Galicia; Magyar Tudományos Akadémia; European Commission","keywords":"Muscarinic acetylcholine receptor; Acetylcholine receptor; Ligand (biochemistry); Acetylcholine; Fluorescence; Muscarinic acetylcholine receptor M5; Chemistry; Computer science; Muscarinic acetylcholine receptor M3; Biophysics; Combinatorial chemistry; Receptor; Pharmacology; Medicine; Biochemistry; Biology; Physics","score_opus":0.020814440417040152,"score_gpt":0.2703035362684855,"score_spread":0.24948909585144538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408665468","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96410286,0.0029367574,0.029609928,0.0027245681,0.00016584217,0.00042818487,0.000007350687,0.0000065204304,0.000017965593],"genre_scores_gemma":[0.9973743,0.00059642154,0.0007925276,0.0006652017,0.00038884277,0.000095724725,0.00004239223,0.000015543936,0.000029028784],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99893117,0.00004916393,0.00025641508,0.0003067786,0.00026482996,0.00019166106],"domain_scores_gemma":[0.9992598,0.00014550288,0.000117943615,0.00027804903,0.00013198705,0.00006671352],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001011582,0.00016035461,0.00018189763,0.00002003036,0.00009374498,0.000015665524,0.0001903486,0.00012635479,0.000015055789],"category_scores_gemma":[0.00042995412,0.00012229879,0.00007112631,0.00007962217,0.000098474695,0.0000035115775,0.000060165385,0.00009844402,4.175545e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016359307,0.00001602597,0.000021866272,0.00008665922,0.000123199,1.774364e-7,0.0000645393,0.00015960062,0.96891665,0.0000026955397,0.0071134577,0.023331527],"study_design_scores_gemma":[0.0009068046,0.000037297774,0.000039383678,0.00013411407,0.00029121412,0.0000041802414,0.00014593735,0.00046560293,0.9964716,0.00004391276,0.0013470502,0.0001129465],"about_ca_topic_score_codex":0.000008989929,"about_ca_topic_score_gemma":0.0000011889063,"teacher_disagreement_score":0.033271436,"about_ca_system_score_codex":0.000027594884,"about_ca_system_score_gemma":0.00018370587,"threshold_uncertainty_score":0.49872002},"labels":[],"label_agreement":null},{"id":"W4408787466","doi":"10.1111/jnc.70048","title":"Hippocampal Inhibitory Interneuron‐Specific <scp>DREADDs</scp> Treatment Alters <scp>mTORC1</scp>‐<scp>4E</scp>‐<scp>BP</scp> Signaling and Impairs Memory Formation","year":2025,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; Université de Montréal; McGill University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"mTORC1; Hippocampal formation; Neuroscience; Inhibitory postsynaptic potential; Excitatory postsynaptic potential; Biology; Cell biology; Signal transduction; PI3K/AKT/mTOR pathway","score_opus":0.01038085585289289,"score_gpt":0.2328066033244908,"score_spread":0.2224257474715979,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408787466","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98506814,0.006832672,0.0031815316,0.00004992137,0.0014139774,0.0004085667,0.00005706906,0.00006598335,0.002922124],"genre_scores_gemma":[0.98900956,0.0032688284,0.0006582564,0.00063594145,0.0019777848,0.000039632916,0.00014873898,0.00014698309,0.0041142497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9951415,0.00027939177,0.0016592061,0.0010382603,0.0007826703,0.001098953],"domain_scores_gemma":[0.9957717,0.000924238,0.0013823349,0.0007318846,0.0005103819,0.00067944295],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007099492,0.0009908078,0.0009812753,0.0003641501,0.00039522484,0.00039671495,0.00081243366,0.0006947619,0.000012482764],"category_scores_gemma":[0.0014834285,0.0009456221,0.00078603404,0.00035988545,0.00022969891,0.00012265526,0.00036383362,0.0009681809,0.000015210995],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023693105,0.0002908061,0.00040478192,0.00026417448,0.0003163513,0.00017830548,0.0010525943,0.0005510083,0.96226686,0.000015237489,0.033513103,0.0011231067],"study_design_scores_gemma":[0.002414225,0.0009942318,0.00028165488,0.0003499544,0.00023339414,0.00073149806,0.006513853,0.00021372191,0.92362636,0.00021486313,0.064323366,0.00010288506],"about_ca_topic_score_codex":0.000007649219,"about_ca_topic_score_gemma":0.000002376965,"teacher_disagreement_score":0.038640484,"about_ca_system_score_codex":0.00027873946,"about_ca_system_score_gemma":0.00040011588,"threshold_uncertainty_score":0.9992994},"labels":[],"label_agreement":null},{"id":"W4408875598","doi":"10.1101/2025.03.24.645031","title":"T-World: A highly general computational model of a human ventricular myocyte","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"ZonMw; Wellcome Trust","keywords":"Mexiletine; Neuroscience; Internal medicine; Computer science; Cardiology; Artificial intelligence; Medicine; Psychology","score_opus":0.0127811487446095,"score_gpt":0.23646648503740045,"score_spread":0.22368533629279094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408875598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9511719,0.0011618331,0.046155542,0.00004276517,0.00047779767,0.00044501602,0.00045541336,0.000059717502,0.00003002445],"genre_scores_gemma":[0.96781737,0.00006509816,0.031359643,0.0001994018,0.00032185233,0.000076049575,0.000008854466,0.000058545105,0.00009321326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99781364,0.00009342062,0.00057209027,0.0008283122,0.0003288257,0.00036373653],"domain_scores_gemma":[0.9981901,0.000010443259,0.0003924907,0.0007610189,0.0005025004,0.000143443],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029879177,0.00043023852,0.0004959705,0.00028609668,0.00012810019,0.00006328792,0.00050849805,0.00045037942,0.000028285922],"category_scores_gemma":[0.00003849948,0.00048088783,0.00030021483,0.00026627994,0.00007379157,0.000005428107,0.000575827,0.00032932177,0.0000036073498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025079173,0.00010292395,0.00035780252,0.00021014018,0.00021788664,0.000008956919,0.0000027408917,0.06754531,0.9271654,0.0038781348,0.0004849963,6.2593205e-7],"study_design_scores_gemma":[0.00053807825,0.000068432935,0.00052810065,0.00020791005,0.00011246136,1.0296315e-8,7.191958e-7,0.02903736,0.9676328,0.000045499466,0.0012984613,0.0005301889],"about_ca_topic_score_codex":0.000024199751,"about_ca_topic_score_gemma":0.00000292794,"teacher_disagreement_score":0.04046737,"about_ca_system_score_codex":0.0000618645,"about_ca_system_score_gemma":0.00067425723,"threshold_uncertainty_score":0.99976426},"labels":[],"label_agreement":null},{"id":"W4409148282","doi":"10.1038/s41593-025-01912-7","title":"Nonlinear recurrent inhibition through facilitating serotonin release in the raphe","year":2025,"lang":"en","type":"article","venue":"Nature Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"General Dynamics (Canada); University of Ottawa","funders":"Krembil Foundation; Fondation Brain Canada","keywords":"Dorsal raphe nucleus; Neuroscience; Serotonergic; Optogenetics; Raphe nuclei; Serotonin; Inhibitory postsynaptic potential; Biology; Psychology; Receptor","score_opus":0.010248592032903943,"score_gpt":0.2920143663368978,"score_spread":0.28176577430399385,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409148282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931096,0.00070256006,0.0037988955,0.00073277653,0.00057014014,0.00026560022,0.000010441925,0.000009155149,0.00080085616],"genre_scores_gemma":[0.99382013,0.00010520143,0.0012239092,0.0046461266,0.000055924935,0.000023893637,0.000014336758,0.000004001786,0.00010646903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990497,0.00010863639,0.00013904671,0.0003512627,0.00017227248,0.00017903832],"domain_scores_gemma":[0.99966437,0.000028653118,0.000039706618,0.00021182367,0.000038543763,0.00001689131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032417197,0.00009489327,0.000067007466,0.000034821474,0.00013250868,0.000043664248,0.00022744197,0.00014225245,0.000004187797],"category_scores_gemma":[0.000453752,0.00006816261,0.000047596837,0.00040219977,0.00006132869,0.000008394481,0.0000638614,0.00037190228,0.0000012412821],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002186439,0.00003980272,0.00012214287,0.000010404265,5.177973e-7,0.000003922688,0.000116317395,0.000112442576,0.996699,0.0007056456,0.00056993146,0.0015980372],"study_design_scores_gemma":[0.00035627044,0.00021473787,0.0005910978,0.000058201374,0.0000036967988,0.000008103924,0.00035516376,0.0014065944,0.943395,0.0007633548,0.05271039,0.00013736583],"about_ca_topic_score_codex":0.000005531233,"about_ca_topic_score_gemma":0.00001079771,"teacher_disagreement_score":0.05330395,"about_ca_system_score_codex":0.0000078204475,"about_ca_system_score_gemma":0.000054371572,"threshold_uncertainty_score":0.27795908},"labels":[],"label_agreement":null},{"id":"W4409484397","doi":"10.1021/acs.jmedchem.5c00678","title":"The Prosperity and Adversity of M<sub>4</sub> Muscarinic Acetylcholine Receptor Activators in the Treatment of Neuropsychiatric Disorders","year":2025,"lang":"en","type":"review","venue":"Journal of Medicinal Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"National Health and Medical Research Council; Australian Research Council","keywords":"Muscarinic acetylcholine receptor; Chemistry; Prosperity; Acetylcholine; Muscarinic acetylcholine receptor M3; Acetylcholine receptor; Neuroscience; Muscarinic acetylcholine receptor M4; Muscarinic acetylcholine receptor M1; Muscarinic acetylcholine receptor M5; Pharmacology; Receptor; Psychology; Biochemistry; Political science; Medicine","score_opus":0.008315775950148015,"score_gpt":0.27156332125275234,"score_spread":0.2632475453026043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409484397","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20824264,0.7911311,0.000009375801,0.00005601408,0.00020785685,0.00026015865,0.000014717904,6.750548e-7,0.00007751525],"genre_scores_gemma":[0.04023125,0.95937485,0.000027238173,0.000008276434,0.00030164057,0.000009401569,0.000016904174,0.00001146033,0.000018960238],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99836046,0.00017851872,0.00074646075,0.00020466531,0.00034808915,0.00016180913],"domain_scores_gemma":[0.9983867,0.00015452251,0.0009879201,0.000294868,0.000113685644,0.00006233247],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007799601,0.00025502502,0.0008135763,0.00005039283,0.00006321154,0.000008208858,0.0003965193,0.00025071047,0.0000075992534],"category_scores_gemma":[0.0002006837,0.00013402419,0.00045289434,0.00022021164,0.0001420387,0.0000036353722,0.000051435058,0.0003462656,6.109332e-8],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022810124,0.00041748752,0.00017259312,0.0056910575,0.0004292725,0.000004201676,0.00014863357,0.000004171446,0.053427346,0.0000027366766,0.00030494647,0.93916947],"study_design_scores_gemma":[0.0033093488,0.0023890727,0.00014938421,0.007687012,0.003029322,0.0002296724,0.0013768128,0.0000057717507,0.16439754,0.000057612022,0.81688476,0.00048371716],"about_ca_topic_score_codex":0.000005164259,"about_ca_topic_score_gemma":0.000004683795,"teacher_disagreement_score":0.9386857,"about_ca_system_score_codex":0.00004515057,"about_ca_system_score_gemma":0.00048275743,"threshold_uncertainty_score":0.5465348},"labels":[],"label_agreement":null},{"id":"W4409687583","doi":"10.1016/j.molpha.2025.100040","title":"Extracellular ATP increases agonist potency and reduces latency at class B G protein-coupled receptors","year":2025,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"Agonist; Extracellular; Receptor; Chemistry; Potency; G protein-coupled receptor; Latency (audio); Cell biology; Pharmacology; Biochemistry; Biophysics; Biology; Computer science; In vitro","score_opus":0.005718394237770888,"score_gpt":0.2506404597319988,"score_spread":0.2449220654942279,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409687583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98201764,0.012882632,0.0019902699,0.00084168196,0.0005883683,0.00062417163,0.000009726124,0.000043429096,0.0010020694],"genre_scores_gemma":[0.9889539,0.0005287451,0.0010882606,0.00074136467,0.00015302059,0.00016192783,0.00011900493,0.00004312826,0.008210651],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980796,0.00021935617,0.00036208102,0.0007212839,0.00014424347,0.00047343018],"domain_scores_gemma":[0.99931633,0.000017301258,0.000129483,0.00026542798,0.00011195215,0.00015947646],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00028136195,0.00032142803,0.00030506903,0.00011514226,0.00027961397,0.000039434337,0.00027535463,0.00032559235,0.00061561464],"category_scores_gemma":[0.00006209249,0.0003237293,0.00014338242,0.00017507515,0.00018602694,0.0000068609897,0.00035133885,0.00018516253,0.000017308457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021028184,0.000114481314,0.00007207659,0.000043651824,0.00018783676,0.00006305792,0.000026616208,0.000046519435,0.9946202,0.0010091889,0.0017719185,0.00183419],"study_design_scores_gemma":[0.00098333,0.00023394382,0.000030278165,0.000022204613,0.00010070686,0.00002504685,0.00003566804,0.0002585268,0.89560527,0.00023201812,0.10217869,0.00029434357],"about_ca_topic_score_codex":0.00007264259,"about_ca_topic_score_gemma":0.0000072570947,"teacher_disagreement_score":0.10040677,"about_ca_system_score_codex":0.000047987585,"about_ca_system_score_gemma":0.0001378414,"threshold_uncertainty_score":0.9999215},"labels":[],"label_agreement":null},{"id":"W4409726902","doi":"10.1101/2025.04.16.649213","title":"Antimuscarinic drugs exert β-arrestin-biased agonism at the muscarinic acetylcholine type 1 receptor","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Uehara Memorial Foundation; Canadian Institutes of Health Research; Japan Science and Technology Agency; Japan Society for the Promotion of Science; Japan Agency for Medical Research and Development","keywords":"Muscarinic acetylcholine receptor; Arrestin; Pharmacology; Muscarinic acetylcholine receptor M1; Functional selectivity; Chemistry; Muscarinic acetylcholine receptor M3; Agonism; Muscarinic acetylcholine receptor M4; Acetylcholine; Muscarinic acetylcholine receptor M5; Receptor; Medicine; Agonist; G protein-coupled receptor; Biochemistry; Political science","score_opus":0.01211476928669286,"score_gpt":0.2352499613647855,"score_spread":0.22313519207809263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409726902","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863899,0.0054158703,0.00072299317,0.00042278686,0.0051803757,0.0011040871,0.00043996458,0.00020388047,0.000120140896],"genre_scores_gemma":[0.9914696,0.0024944267,0.0024177833,0.00091624685,0.0015272351,0.0001833718,0.000020290581,0.00017773872,0.000793303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9958365,0.00031458575,0.0007919124,0.0017204324,0.00048625132,0.00085029646],"domain_scores_gemma":[0.9957933,0.00008410827,0.00053511915,0.0026516225,0.0006418616,0.00029400946],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00096701435,0.0008839168,0.00071859575,0.00016482173,0.00047302374,0.0002267079,0.0013613182,0.0011826453,0.00042323896],"category_scores_gemma":[0.00041232473,0.0007818879,0.00046454996,0.0004819552,0.00021134983,0.000010316395,0.0021912227,0.0009821625,0.00015561514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014380719,0.000093332455,0.00063551014,0.00017338121,0.00030044612,0.000006191156,0.000013067824,0.00024797893,0.99150515,0.000111435475,0.0067538847,0.000015843087],"study_design_scores_gemma":[0.00070158823,0.00010497991,0.0014349212,0.00030903294,0.0001800247,3.6073665e-8,0.0000074198283,0.00016478552,0.88102263,0.0000019942472,0.11517375,0.00089881895],"about_ca_topic_score_codex":0.00007922776,"about_ca_topic_score_gemma":0.000011302589,"teacher_disagreement_score":0.11048247,"about_ca_system_score_codex":0.0001650967,"about_ca_system_score_gemma":0.0011111174,"threshold_uncertainty_score":0.9994632},"labels":[],"label_agreement":null},{"id":"W4409764776","doi":"10.1101/2025.04.23.650231","title":"Midbrain organoids with an SNCA gene triplication display dopamine-dependent alterations in network activity","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Midbrain; Organoid; Dopamine; Gene; Neuroscience; Biology; Cell biology; Computational biology; Genetics; Central nervous system","score_opus":0.008425281783295288,"score_gpt":0.22568253453077014,"score_spread":0.21725725274747484,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409764776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9500224,0.00048507957,0.047913574,0.00008843184,0.00044257852,0.00077126996,0.000193511,0.000070179514,0.000012997248],"genre_scores_gemma":[0.9891832,0.00019304584,0.009288436,0.00017833036,0.000723333,0.00030564208,0.000012788242,0.000075976386,0.000039271647],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974571,0.00023835055,0.0003970859,0.0011848537,0.00024736204,0.0004752709],"domain_scores_gemma":[0.99799156,0.000019711639,0.00028284124,0.0012567805,0.0002686825,0.00018043123],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000540909,0.0004839132,0.0004156966,0.0001471932,0.00017246616,0.00017332278,0.00046764838,0.00060209376,0.000022133498],"category_scores_gemma":[0.00005858904,0.0004883771,0.00009076791,0.000357748,0.000050927138,0.000019597892,0.00033111652,0.0004842658,0.0000042989354],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016021685,0.00017984874,0.0024939585,0.0000762601,0.000088205634,0.000009879868,0.000004896966,0.002480898,0.9941811,0.0002680202,0.0000469841,0.000009751497],"study_design_scores_gemma":[0.000618069,0.00018496237,0.012150838,0.00016149222,0.000060578575,3.1837857e-8,0.0000024637723,0.0014498521,0.98382866,0.0000033090444,0.0009324502,0.0006073113],"about_ca_topic_score_codex":0.000066345056,"about_ca_topic_score_gemma":0.00009730472,"teacher_disagreement_score":0.039160796,"about_ca_system_score_codex":0.00011174179,"about_ca_system_score_gemma":0.00065987045,"threshold_uncertainty_score":0.9997568},"labels":[],"label_agreement":null},{"id":"W4409963331","doi":"10.1139/cjpp-2025-0004","title":"The calcium-sensitive receptor in the pathogenesis of sepsis","year":2025,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Sepsis; Organ dysfunction; Pathogenesis; Calcium-sensing receptor; Receptor; Medicine; Signal transduction; Immunology; Biology; Bioinformatics; Calcium; Internal medicine; Cell biology; Calcium metabolism","score_opus":0.022233957286085813,"score_gpt":0.31482713800085144,"score_spread":0.29259318071476564,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409963331","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00556228,0.99277526,0.000016131351,0.0001656227,0.001073313,0.00023817895,0.00008976681,4.2546216e-7,0.000079004436],"genre_scores_gemma":[0.010512426,0.98848474,0.000030266729,0.00040088082,0.00042534442,0.000017629047,0.000030699965,0.000011524976,0.00008646048],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979525,0.0010158046,0.0005248827,0.00018254324,0.00004801799,0.00027624596],"domain_scores_gemma":[0.99879354,0.0003812508,0.0004415346,0.00013955576,0.0001344314,0.00010969143],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00070194213,0.0002031754,0.0007136525,0.00015017971,0.00016379784,0.000008326539,0.00042002415,0.00036635748,0.00012566173],"category_scores_gemma":[0.00008195829,0.000115984876,0.00029445367,0.00015874524,0.00028524795,0.0000024057033,0.00003441347,0.0003870242,0.0000010682355],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001393246,0.00004468651,0.000014003211,0.0034513879,0.0011871293,0.00007502106,0.0003756562,0.000022021775,0.6354933,0.0005110561,0.017730126,0.34095633],"study_design_scores_gemma":[0.0002214606,0.00025995326,0.000017942353,0.00046933288,0.00037940594,0.000082950646,0.00013273445,9.3682183e-7,0.018560912,0.00012911657,0.9796072,0.00013805243],"about_ca_topic_score_codex":0.0001360208,"about_ca_topic_score_gemma":0.0004668387,"teacher_disagreement_score":0.96187705,"about_ca_system_score_codex":0.000024313696,"about_ca_system_score_gemma":0.0014698514,"threshold_uncertainty_score":0.4729726},"labels":[],"label_agreement":null},{"id":"W4410069003","doi":"10.1101/2025.05.02.651384","title":"Profiling of HCAR1 signaling reveals Gα <sub>i/o</sub> and Gα <sub>s</sub> activation without β-arrestin recruitment and the discovery of an allosteric agonist","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; Novo Nordisk Fonden; Stiftelsen Konung Gustaf V:s 80-årsfond; Vetenskapsrådet; Novo Nordisk; Natural Sciences and Engineering Research Council of Canada; Karolinska Institutet; AstraZeneca; European Foundation for the Study of Diabetes; Stiftelsen för Strategisk Forskning; Svenska Sällskapet för Medicinsk Forskning","keywords":"Allosteric regulation; Agonist; Arrestin; Profiling (computer programming); Drug discovery; Computational biology; Chemistry; Cell biology; Receptor; G protein-coupled receptor; Signal transduction; Biology; Computer science; Biochemistry","score_opus":0.017084716691349856,"score_gpt":0.23815085750085116,"score_spread":0.2210661408095013,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410069003","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99075335,0.0016149798,0.005420771,0.000061104234,0.00033047938,0.0015969328,0.00018572366,0.000032768356,0.000003908634],"genre_scores_gemma":[0.99484503,0.0011064117,0.0033792253,0.000090001275,0.00025278554,0.00024389722,0.00000839846,0.00007211617,0.0000021254282],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997044,0.00040432054,0.0008213581,0.0010204082,0.00032995405,0.00037994972],"domain_scores_gemma":[0.9975666,0.000087649445,0.0009205689,0.00089021254,0.00040127945,0.00013372395],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012350123,0.00054230314,0.000773368,0.00015325326,0.00018902152,0.00017171577,0.00036002594,0.00053172937,9.979676e-7],"category_scores_gemma":[0.00028675544,0.00047474977,0.00016477157,0.00022679652,0.00028877266,0.00003663207,0.0006236994,0.00039985674,2.968239e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035275536,0.00007783653,0.00151857,0.0007809763,0.00023114463,0.0000024896276,0.000023990598,0.00020174352,0.9963498,0.00039532484,0.00000541691,0.00005994934],"study_design_scores_gemma":[0.0009568896,0.00016657305,0.0021529477,0.000994385,0.00019369822,8.183072e-8,0.000023177408,0.00036286164,0.9946392,0.000024381594,0.00003050652,0.00045526214],"about_ca_topic_score_codex":0.000028898245,"about_ca_topic_score_gemma":0.0000039420743,"teacher_disagreement_score":0.004091707,"about_ca_system_score_codex":0.000049162674,"about_ca_system_score_gemma":0.0004288074,"threshold_uncertainty_score":0.9997704},"labels":[],"label_agreement":null},{"id":"W4410537865","doi":"10.1038/s41380-025-03023-y","title":"Cholinergic system in schizophrenia: A systematic review and meta-analysis","year":2025,"lang":"en","type":"review","venue":"Molecular Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Ottawa Hospital; Royal Ottawa Mental Health Centre; Université du Québec en Outaouais; University of Ottawa","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Meta-analysis; Schizophrenia (object-oriented programming); Cholinergic; Psychology; Neuroscience; Cholinergic system; Psychosis; MEDLINE; Medicine; Psychiatry; Internal medicine; Biology","score_opus":0.016761911164817785,"score_gpt":0.29855371928537305,"score_spread":0.28179180812055526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410537865","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0000021086712,0.9956884,0.0014411858,0.000045729365,0.00015927486,0.0022712164,0.00008758138,0.000022594131,0.00028192453],"genre_scores_gemma":[0.0000506052,0.9961852,0.0012712332,0.00048774475,0.000043045882,0.0010622335,0.0003295402,0.00006229549,0.0005080984],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9962113,0.0007753616,0.0013934559,0.0010401802,0.00024114441,0.00033855787],"domain_scores_gemma":[0.9979632,0.000022431273,0.0005871995,0.0012433238,0.00006642572,0.00011744146],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00079157733,0.0007421461,0.006928098,0.00046833107,0.00005945848,0.000063472384,0.0005123329,0.0004691697,0.000048168702],"category_scores_gemma":[0.00007277729,0.0005484561,0.0037557024,0.0010320502,0.000025886055,0.0000029425612,0.00020471677,0.00033109693,0.000011432861],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000022740005,0.000028757768,1.8088376e-7,0.92949796,0.06940709,0.000014559704,0.0000011361739,0.000010417144,0.0000055582145,0.00074380275,0.00014860326,0.00013965291],"study_design_scores_gemma":[0.00016841589,0.000038361028,4.1426848e-8,0.06507403,0.92688596,0.00006565803,0.000010561525,0.0000063812013,0.000007860114,0.000020136982,0.0071243453,0.00059827423],"about_ca_topic_score_codex":0.0000107941605,"about_ca_topic_score_gemma":0.00001800367,"teacher_disagreement_score":0.86442393,"about_ca_system_score_codex":0.000032966473,"about_ca_system_score_gemma":0.00029475725,"threshold_uncertainty_score":0.9996967},"labels":[],"label_agreement":null},{"id":"W4410765029","doi":"10.17504/protocols.io.4r3l2br2jl1y/v1","title":"Live-Imaging of GCase Activity in iPSC-Derived Dopaminergic Neurons Using the PFB-FDGlu Probe v1","year":2025,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Dopaminergic; Neuroscience; Psychology; Dopamine","score_opus":0.02202081467693019,"score_gpt":0.27742957506159593,"score_spread":0.25540876038466576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410765029","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9706205,0.0006200589,0.026598683,0.00015771374,0.0004098244,0.0005093299,0.000036877518,0.000014318365,0.0010326833],"genre_scores_gemma":[0.9962892,0.00020471627,0.0026202737,0.00014122299,0.00013097649,0.0000355803,0.000043819404,0.000024278641,0.00050992216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99838376,0.00021134145,0.00034449197,0.0006176912,0.00015377536,0.0002889121],"domain_scores_gemma":[0.9989155,0.000033893342,0.00023418243,0.00066579756,0.00010242043,0.000048189682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003357197,0.00031016913,0.0003529629,0.00009828374,0.00007666593,0.00004362299,0.0004207961,0.00024671183,0.00007650092],"category_scores_gemma":[0.00007560121,0.00024093472,0.00021957695,0.000106079904,0.00008012336,0.0000036620233,0.0011370069,0.0004290449,8.1941687e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005019391,0.00008452887,0.000586638,0.00013187903,0.000043763466,0.000009394988,0.00010544329,0.006001492,0.99141663,0.00008155644,0.000041090905,0.0014473946],"study_design_scores_gemma":[0.00034998864,0.00004798234,0.00033416244,0.00019270448,0.00005500824,0.000010582682,0.00026278902,0.019823287,0.97805244,0.00024711573,0.0003020019,0.00032191363],"about_ca_topic_score_codex":0.0008660233,"about_ca_topic_score_gemma":0.00015985357,"teacher_disagreement_score":0.0256687,"about_ca_system_score_codex":0.000029912879,"about_ca_system_score_gemma":0.00029159657,"threshold_uncertainty_score":0.98250324},"labels":[],"label_agreement":null},{"id":"W4410833265","doi":"10.1101/2025.05.27.656467","title":"System-wide dissociation of reward and aversive dopaminergic signals","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Air Force Office of Scientific Research; Canadian Institutes of Health Research; Peking University; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada","keywords":"Dopaminergic; Dissociation (chemistry); Reward system; Psychology; Neuroscience; Cognitive psychology; Dopamine; Chemistry","score_opus":0.006384810450024811,"score_gpt":0.2049419728977112,"score_spread":0.1985571624476864,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410833265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9903947,0.0024483693,0.005502922,0.00005097285,0.0006887676,0.00047892905,0.0003392202,0.00005238044,0.000043721837],"genre_scores_gemma":[0.99733,0.000495785,0.0017282127,0.00006226316,0.0002544656,0.000049456215,0.000002548293,0.000038968967,0.000038293936],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982109,0.00013613513,0.0004524435,0.00069934496,0.00022238177,0.00027879194],"domain_scores_gemma":[0.9983639,0.000039638955,0.0004892265,0.0005911243,0.00039737692,0.00011875044],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042495914,0.00034849584,0.00048207666,0.00013738114,0.00009025781,0.000056365683,0.0002846828,0.00058580877,0.000012435642],"category_scores_gemma":[0.00021519391,0.00037483976,0.00015991495,0.00015384534,0.00005995447,0.0000052530904,0.00044056575,0.0002255787,0.000002550848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033893277,0.000030365636,0.0029566037,0.0007259636,0.00020640783,0.000005077873,0.0000066435305,0.00017635281,0.99493915,0.00068505417,0.00023337096,0.0000011090996],"study_design_scores_gemma":[0.00033736814,0.00007469666,0.003141936,0.0005755896,0.00013454762,9.084702e-9,0.000016816637,0.00013727623,0.9935258,0.0000021380665,0.0016726399,0.00038118105],"about_ca_topic_score_codex":0.00003982751,"about_ca_topic_score_gemma":0.0000016317964,"teacher_disagreement_score":0.0069352896,"about_ca_system_score_codex":0.00006858914,"about_ca_system_score_gemma":0.0003174105,"threshold_uncertainty_score":0.99987036},"labels":[],"label_agreement":null},{"id":"W4410846053","doi":"10.22541/au.174855614.47209749/v1","title":"Molecular dynamics simulations reveal the impact of Ser295 phosphorylation on the structure of pyrin domain-containing NOD-like receptor 3","year":2025,"lang":"en","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Pyrin domain; Nod; Domain (mathematical analysis); Phosphorylation; Dynamics (music); Receptor; Computational biology; Biology; Cell biology; Physics; Genetics; Inflammasome; Gene; Mathematics","score_opus":0.00829266820113813,"score_gpt":0.26544735923984797,"score_spread":0.25715469103870986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410846053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98133415,0.0002180787,0.01575295,0.00014512212,0.00029794197,0.0006616713,0.00072531844,0.000009748992,0.00085500244],"genre_scores_gemma":[0.99717605,0.000030346991,0.0013838942,0.00010839985,0.000082782084,0.0000085517095,0.0008845188,0.000027432636,0.00029802215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842376,0.00019148296,0.0005021399,0.0004225693,0.00024625228,0.0002138085],"domain_scores_gemma":[0.99823636,0.000097175274,0.00046455703,0.00088411086,0.00027708794,0.00004068314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002886478,0.00032928443,0.00035005997,0.00006471755,0.000118048054,0.000031481766,0.0005173095,0.00048124636,0.00027542305],"category_scores_gemma":[0.00009864669,0.00019300764,0.000452534,0.00013837455,0.00008016668,0.0000024419169,0.00040128132,0.00041839233,5.418151e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016046625,0.000030600626,0.00028080365,0.000043422544,0.00036742966,2.4850183e-7,0.00023318823,0.19722229,0.7966499,0.004309443,0.00019015679,0.00051208155],"study_design_scores_gemma":[0.0003471966,0.00036837163,0.00028101786,0.00016910017,0.00007218865,0.0000010389303,0.00048047627,0.021113902,0.9703573,0.006387615,0.00012215482,0.00029961718],"about_ca_topic_score_codex":0.00033155546,"about_ca_topic_score_gemma":0.0000723048,"teacher_disagreement_score":0.17610839,"about_ca_system_score_codex":0.00010963286,"about_ca_system_score_gemma":0.00042647278,"threshold_uncertainty_score":0.78706235},"labels":[],"label_agreement":null},{"id":"W4410876610","doi":"10.1101/2025.05.28.656610","title":"Molecular dynamics simulations reveal the impact of Ser295 phosphorylation on the structure of pyrin domain-containing NOD-like receptor 3","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Pyrin domain; Nod; Phosphorylation; Domain (mathematical analysis); Dynamics (music); Molecular dynamics; Receptor; Cell biology; Chemistry; Inflammasome; Computational biology; Biology; Physics; Biochemistry; Gene; Mathematics","score_opus":0.006991166985859271,"score_gpt":0.2305839230924184,"score_spread":0.22359275610655913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410876610","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919629,0.0004621032,0.004863011,0.000090656016,0.0004647479,0.0007745619,0.0013445289,0.000023528328,0.000013964675],"genre_scores_gemma":[0.998137,0.0000468399,0.0014676254,0.000092695365,0.00015331697,0.000018755012,0.000013548109,0.00006194389,0.0000082660745],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99787915,0.00025421704,0.00060191454,0.0006155096,0.0003203637,0.00032883286],"domain_scores_gemma":[0.9972174,0.000092897986,0.00070403796,0.0013465068,0.00055981363,0.00007933754],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042370087,0.00046330914,0.00045642187,0.00011368834,0.0001783817,0.000059213246,0.00068098056,0.00059009786,0.00007138454],"category_scores_gemma":[0.00020291984,0.00032615458,0.00039199728,0.00033405665,0.00012442566,0.000006870579,0.00037877157,0.0005513767,0.0000010824773],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012458002,0.000046043682,0.0012518712,0.00008021716,0.0003729525,9.4955976e-7,0.000028305305,0.027245516,0.96860456,0.002169324,0.00007186642,0.0000037800057],"study_design_scores_gemma":[0.00031249158,0.00019803946,0.0029176725,0.00025591103,0.000077491924,1.1219698e-8,0.000022845066,0.0036656149,0.99202925,0.000043923475,0.00014136064,0.00033536405],"about_ca_topic_score_codex":0.00011869177,"about_ca_topic_score_gemma":0.00000953753,"teacher_disagreement_score":0.023579901,"about_ca_system_score_codex":0.00017796982,"about_ca_system_score_gemma":0.00086326286,"threshold_uncertainty_score":0.99991906},"labels":[],"label_agreement":null},{"id":"W4410894568","doi":"10.3390/molecules30112399","title":"Gating Mechanism for Biased Agonism at Angiotensin II Type 1 Receptors","year":2025,"lang":"en","type":"article","venue":"Molecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Victoria University; RMIT University","keywords":"Chemistry; Carboxylate; Angiotensin II; Receptor; Biophysics; Stereochemistry; Biochemistry; Biology","score_opus":0.0124507147843684,"score_gpt":0.2545384756880195,"score_spread":0.2420877609036511,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410894568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92793417,0.00069457246,0.06784652,0.0005776632,0.0011519263,0.0004211186,0.000021663971,0.00004928744,0.001303061],"genre_scores_gemma":[0.9614236,0.00007953568,0.0268647,0.0017289566,0.00021881885,0.00005096248,0.0003095955,0.000048508293,0.009275332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989776,0.00003723809,0.00020699951,0.0003939179,0.000093140225,0.00029110533],"domain_scores_gemma":[0.9994057,0.000018264906,0.00007144162,0.00026733492,0.00017960665,0.000057665304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015343924,0.00018030334,0.00016497103,0.00006160468,0.00033897278,0.000027786202,0.00015835567,0.00019761559,0.000066462715],"category_scores_gemma":[0.00015646484,0.00017712062,0.0001486366,0.00012151544,0.000029112593,0.0000022644153,0.00017477394,0.000055805453,0.000007975684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000073984425,0.000021870232,0.000015202508,0.000013940359,0.000056527402,0.0000011035215,0.000038331917,0.000045391294,0.98253405,0.007197132,0.008098187,0.0019043072],"study_design_scores_gemma":[0.00043378508,0.0002626897,0.000011134777,0.000033003107,0.000027546917,0.0000023338348,0.000057474805,0.0005387564,0.9511329,0.002539785,0.044767886,0.00019273532],"about_ca_topic_score_codex":0.000015301903,"about_ca_topic_score_gemma":0.000018448558,"teacher_disagreement_score":0.040981825,"about_ca_system_score_codex":0.000027689206,"about_ca_system_score_gemma":0.00006332921,"threshold_uncertainty_score":0.7222769},"labels":[],"label_agreement":null},{"id":"W4410907203","doi":"10.1111/bph.70072","title":"Biodiversity2Drugs—Renaissance of exploring nature‐derived peptides for GPCR ligand discovery","year":2025,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Université de Montréal; Université de Sherbrooke","funders":"Agencia Estatal de Investigación; Fundação para a Ciência e a Tecnologia; Fundación Biodiversidad; Vlaamse regering; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Agence Nationale de la Recherche; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; Biodiversa+; European Commission; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Conselho Nacional das Fundações Estaduais de Amparo à Pesquisa; Innovationsfonden; Norges Forskningsråd; Austrian Science Fund; Vetenskapsrådet; National Science Foundation","keywords":"The Renaissance; G protein-coupled receptor; Drug discovery; Computational biology; Data science; Ligand (biochemistry); Chemistry; Computer science; Neuroscience; Biology; Bioinformatics; Receptor; Biochemistry; Art; Art history","score_opus":0.016795720460498736,"score_gpt":0.277989091024899,"score_spread":0.2611933705644003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410907203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981977,0.008530809,0.00760532,0.00014829653,0.0014857933,0.000117643256,0.000043959164,0.0000026277962,0.00008855285],"genre_scores_gemma":[0.99422026,0.0032395136,0.0016673837,0.00030579715,0.00036068924,0.0000107628875,0.000008899496,0.000008370848,0.0001783116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999228,0.000050304257,0.0003103824,0.00015529916,0.00008113781,0.00017487172],"domain_scores_gemma":[0.9993747,0.000040815474,0.00024495664,0.00004598714,0.00025222066,0.000041326744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027541918,0.000092657894,0.00024618194,0.000081369275,0.00009101843,0.000026688323,0.00023920987,0.00013137906,0.000030191512],"category_scores_gemma":[0.000079137964,0.00010644296,0.00019394342,0.00007394261,0.00007545968,0.000022771303,0.00008307597,0.00018205309,2.5950592e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030174665,0.000065373446,0.00019980576,0.00005943406,0.00021807903,0.0000246943,0.000022928545,0.000097676486,0.9803706,0.000060633545,0.014355942,0.0042231036],"study_design_scores_gemma":[0.0015200592,0.00025873038,0.00033207334,0.00011461775,0.000092180606,0.0000944469,0.00014233237,0.000012234103,0.98559475,0.00015881608,0.011585964,0.00009382249],"about_ca_topic_score_codex":0.000007743107,"about_ca_topic_score_gemma":0.0000039233514,"teacher_disagreement_score":0.012243273,"about_ca_system_score_codex":0.000014055225,"about_ca_system_score_gemma":0.00010242279,"threshold_uncertainty_score":0.4340618},"labels":[],"label_agreement":null},{"id":"W4411156615","doi":"10.1080/17460441.2025.2515045","title":"Advances in the application of NMR to the study of GPCRs and ligand–GPCR interactions","year":2025,"lang":"en","type":"review","venue":"Expert Opinion on Drug Discovery","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Drug discovery; Computational biology; Nuclear magnetic resonance spectroscopy; Identification (biology); Ligand (biochemistry); Chemistry; Bioinformatics; Data science; Computer science; Biology; Receptor; Biochemistry; Stereochemistry","score_opus":0.019607222579546512,"score_gpt":0.36110909444700834,"score_spread":0.34150187186746184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411156615","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00092044345,0.9965039,0.00076564326,0.0000823288,0.0003184396,0.0011084971,0.000025482275,0.0000018342386,0.00027343817],"genre_scores_gemma":[0.018573595,0.9805963,0.000015918693,0.00007929554,0.00015444178,0.00040592797,0.00007499079,0.000010161147,0.00008936708],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989866,0.00017183348,0.00035168655,0.00028014492,0.00012769013,0.00008204888],"domain_scores_gemma":[0.99926025,0.00011117599,0.00018896998,0.00040146124,0.000024019879,0.000014134449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022629206,0.00016067193,0.0003722126,0.000077403995,0.00004834544,0.000020889223,0.000296706,0.00005868626,0.0000020403588],"category_scores_gemma":[0.000035907662,0.00008772011,0.00011695952,0.00016943163,0.00002119395,0.000008323878,0.0001023698,0.00010618797,6.958214e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048478032,0.0004361315,0.000008041369,0.0008647101,0.000059306047,1.6763673e-7,0.00135218,0.00012748319,0.0007916883,0.0007193753,0.0011998231,0.99439263],"study_design_scores_gemma":[0.00011634403,0.00019257108,0.0000031353247,0.0016229269,0.000011685851,0.0000010758705,0.0024261826,0.0000036941767,0.0013616724,0.000013468637,0.9941479,0.000099321645],"about_ca_topic_score_codex":0.00004598504,"about_ca_topic_score_gemma":0.00006894618,"teacher_disagreement_score":0.9942933,"about_ca_system_score_codex":0.000009663946,"about_ca_system_score_gemma":0.000053633346,"threshold_uncertainty_score":0.3577122},"labels":[],"label_agreement":null},{"id":"W4411210549","doi":"10.3390/biom15060855","title":"Docking Simulations of G-Protein Coupled Receptors Uncover Crossover Binding Patterns of Diverse Ligands to Angiotensin, Alpha-Adrenergic and Opioid Receptors: Implications for Cardiovascular Disease and Addiction","year":2025,"lang":"en","type":"article","venue":"Biomolecules","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Receptor; Opioid; Adrenergic receptor; Docking (animal); Alpha-2 adrenergic receptor; Pharmacology; G protein-coupled receptor; Alpha (finance); Addiction; Chemistry; Medicine; Computational biology; Bioinformatics; Neuroscience; Internal medicine; Biology; Clinical psychology","score_opus":0.011957107993604617,"score_gpt":0.2574435745414144,"score_spread":0.2454864665478098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411210549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93557274,0.0023414276,0.06105197,0.00007724646,0.00014086899,0.0004662797,0.00033561452,0.000009321187,0.000004558309],"genre_scores_gemma":[0.9976047,0.00024568557,0.0016551978,0.000038558504,0.00006049096,0.00003941163,0.00026260436,0.00001766617,0.00007567206],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990975,0.000025013764,0.00025501449,0.00036613166,0.00009677086,0.00015953464],"domain_scores_gemma":[0.9993175,0.000024067329,0.000095916526,0.00027543135,0.00019184545,0.00009524224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013264222,0.00015003569,0.00021751584,0.00013487737,0.00013838218,0.00002913822,0.00008232952,0.000106035055,0.000009920143],"category_scores_gemma":[0.000116760384,0.00015036379,0.00019810947,0.00016744966,0.00006544014,0.000009909009,0.00011455576,0.000028026107,1.6728255e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012990381,0.00003213804,0.0037539604,0.000060273418,0.00035936414,2.1353665e-7,0.000047822243,0.0012376428,0.99114054,0.00057137274,0.00010428014,0.0025624717],"study_design_scores_gemma":[0.0011091284,0.00019103427,0.0033917655,0.0002151241,0.0003601281,8.336548e-7,0.00011901391,0.00076195726,0.9882708,0.0002931577,0.005037478,0.000249566],"about_ca_topic_score_codex":0.00010977494,"about_ca_topic_score_gemma":0.000016573256,"teacher_disagreement_score":0.062032,"about_ca_system_score_codex":0.0000159496,"about_ca_system_score_gemma":0.000051948915,"threshold_uncertainty_score":0.61316574},"labels":[],"label_agreement":null},{"id":"W4411401749","doi":"10.1126/sciadv.adv9267","title":"Discovery of a functionally selective serotonin receptor (5-HT <sub>1A</sub> R) agonist for the treatment of pain","year":2025,"lang":"en","type":"article","venue":"Science Advances","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; Elitenetzwerk Bayern; Japan Science and Technology Agency; Studienstiftung des Deutschen Volkes; Université de Montréal; Deutsche Forschungsgemeinschaft; Genentech; Boehringer Ingelheim Stiftung; European Commission; Julius-Maximilians-Universität Würzburg; Open Philanthropy Project; Japan Society for the Promotion of Science; Verband der Chemischen Industrie","keywords":"Heterotrimeric G protein; Agonist; 5-HT receptor; Receptor; Serotonin; G protein-coupled receptor; Ligand (biochemistry); Chemistry; G protein; Biophysics; Partial agonist; Pharmacology; Cell biology; Neuroscience; Biology; Biochemistry","score_opus":0.007127912771202818,"score_gpt":0.26028704403696823,"score_spread":0.2531591312657654,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411401749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9143612,0.0039497316,0.08027559,0.00016960631,0.0004379729,0.0005579692,0.00004959784,0.0000048026695,0.0001935703],"genre_scores_gemma":[0.9968007,0.00068154803,0.0018013845,0.00006363633,0.000060429356,0.00013952189,0.000013977237,0.0000046830437,0.00043408226],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999238,0.000029863928,0.00016206078,0.00026987938,0.00013884439,0.00016134095],"domain_scores_gemma":[0.99943393,0.000093253,0.00010913633,0.0001701911,0.00017558517,0.0000178842],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045180885,0.00009173635,0.00012149691,0.000042141648,0.00019851894,0.000021475129,0.00019579669,0.000033195083,0.000003115952],"category_scores_gemma":[0.00012481333,0.000059144408,0.00009550422,0.00027656433,0.0003374737,0.00001892527,0.000024240959,0.000019026802,2.939778e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013340697,0.00006663654,0.00023198426,0.000015314901,0.000027160058,2.8959601e-8,0.000053238426,0.00047967004,0.9653847,0.0005905359,0.000065933,0.032951366],"study_design_scores_gemma":[0.00023141727,0.0010325362,0.0001658397,0.000020931535,0.000013844277,2.3074638e-7,0.00034985735,0.0001149675,0.98682463,0.0006261588,0.010558212,0.00006137689],"about_ca_topic_score_codex":0.000007936316,"about_ca_topic_score_gemma":0.000029761411,"teacher_disagreement_score":0.08243957,"about_ca_system_score_codex":0.000029965877,"about_ca_system_score_gemma":0.0002900586,"threshold_uncertainty_score":0.24118389},"labels":[],"label_agreement":null},{"id":"W4411413756","doi":"10.1080/13543784.2025.2522885","title":"Acetylcholine and muscarinic receptor targeting in bipolar disorder: does xanomeline-trospium chloride and other investigational muscarinic agonists hold promise as mechanistically informed treatments for manic episodes, mixed features and cognitive deficits in bipolar disorder?","year":2025,"lang":"en","type":"review","venue":"Expert Opinion on Investigational Drugs","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Muscarinic acetylcholine receptor; Mania; Bipolar disorder; Pharmacology; Medicine; Muscarinic acetylcholine receptor M4; Muscarinic acetylcholine receptor M1; Muscarinic acetylcholine receptor M3; Investigational Drugs; Acetylcholine; Cognition; Internal medicine; Psychiatry; Receptor; Clinical trial","score_opus":0.018240322109553266,"score_gpt":0.31328305457724753,"score_spread":0.29504273246769425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411413756","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.028885411,0.96656823,0.0001909708,0.00033780525,0.0004725576,0.002515204,0.0009787234,0.000026362495,0.00002473979],"genre_scores_gemma":[0.0019742197,0.98461473,0.0032530369,0.00072285975,0.0003878657,0.0016781057,0.007026775,0.00010653974,0.00023584455],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99663204,0.00026698294,0.0010485465,0.001207836,0.00034917786,0.00049540726],"domain_scores_gemma":[0.9982916,0.0006115809,0.00044255567,0.00023266532,0.00014013602,0.0002814646],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00055821537,0.0007890905,0.0010584602,0.00043283016,0.00025972768,0.00016658906,0.00023337599,0.00075477234,0.000020757512],"category_scores_gemma":[0.001687053,0.0006575173,0.00019511992,0.00030369114,0.00029431004,0.000047721252,0.0002638983,0.00044548165,0.0000024727835],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014737432,0.0010791615,0.003972447,0.013918656,0.0016558216,0.0000066086604,0.0024958944,0.00005619201,0.010871381,0.040910218,0.0015137935,0.92204607],"study_design_scores_gemma":[0.0063537643,0.00094001484,0.00061535515,0.014112606,0.00017539682,0.000024427143,0.0006035986,0.00036694683,0.0059217666,0.0048060725,0.96425676,0.0018232662],"about_ca_topic_score_codex":0.00024774772,"about_ca_topic_score_gemma":0.00014237451,"teacher_disagreement_score":0.962743,"about_ca_system_score_codex":0.000111712856,"about_ca_system_score_gemma":0.00079330325,"threshold_uncertainty_score":0.9995876},"labels":[],"label_agreement":null},{"id":"W4411437172","doi":"10.7554/elife.101105.2.sa4","title":"eLife Assessment: Ultraslow serotonin oscillations in the hippocampus delineate substates across NREM and waking","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Hippocampus; Non-rapid eye movement sleep; Serotonin; Physics; Neuroscience; Psychology; Internal medicine; Electroencephalography; Medicine","score_opus":0.019830469032948952,"score_gpt":0.35160482336936494,"score_spread":0.331774354336416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411437172","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.29502797,0.49652562,0.05708495,0.076715074,0.008185203,0.012506562,0.003619285,0.00023596402,0.05009936],"genre_scores_gemma":[0.31096393,0.51314265,0.014283571,0.034536075,0.0019809543,0.0011844008,0.018522931,0.00023173519,0.10515377],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980336,0.00020320849,0.0005000263,0.00059393013,0.00028206533,0.0003871912],"domain_scores_gemma":[0.99903846,0.00008235659,0.00017152018,0.00045226744,0.00020058683,0.00005482528],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0011673094,0.0003542882,0.00042261227,0.000050714014,0.00020451617,0.00013817965,0.00036449052,0.0003576747,0.000116785],"category_scores_gemma":[0.00010512541,0.00025034096,0.00015382424,0.0001967555,0.000051143295,0.000004443317,0.00014719661,0.00037592402,0.000002672832],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000056233468,0.00025562802,0.0019354995,0.005558783,0.0006468442,0.00004333751,0.000693567,0.00062969426,0.0848126,0.001004727,0.65957576,0.24478732],"study_design_scores_gemma":[0.00037476773,0.00008261933,0.000119909484,0.0013872094,0.00008459517,0.000020438685,0.00032525958,0.00037929037,0.006147178,0.00043510034,0.99018466,0.00045896583],"about_ca_topic_score_codex":0.00015902176,"about_ca_topic_score_gemma":0.0007348748,"teacher_disagreement_score":0.3306089,"about_ca_system_score_codex":0.000024799943,"about_ca_system_score_gemma":0.00020403518,"threshold_uncertainty_score":0.9999949},"labels":[],"label_agreement":null},{"id":"W4411555666","doi":"10.1016/j.cell.2025.05.042","title":"GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity","year":2025,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Science for Life Laboratory; Vetenskapsrådet; Novo Nordisk; Insamlingsstiftelsen Diabetes Wellness Network Sverige; Novo Nordisk Fonden; Svenska Sällskapet för Medicinsk Forskning; National Science Council; Knut och Alice Wallenbergs Stiftelse; Robert Bosch Stiftung; Deutsche Forschungsgemeinschaft; Cancerfonden; Augusta University; European Foundation for the Study of Diabetes; Uppsala Multidisciplinary Center for Advanced Computational Science; European Federation of Pharmaceutical Industries and Associations; Karolinska Institutet; McGill University","keywords":"Biology; Type 2 diabetes; Obesity; Endocrinology; Internal medicine; Adrenergic; Diabetes mellitus; Pharmacology; Receptor; Genetics","score_opus":0.008627477684094722,"score_gpt":0.23241688339622646,"score_spread":0.22378940571213174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411555666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922155,0.0065057785,0.0006248524,0.000024705056,0.00014026773,0.00012813282,0.000007070309,0.0000021386545,0.0003515176],"genre_scores_gemma":[0.9964889,0.0009383468,0.000263962,0.000047869893,0.000042591982,0.000013296312,0.000026835469,0.0000039586703,0.0021742042],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997371,0.000009416806,0.000059229576,0.00010292898,0.000018901334,0.000072422816],"domain_scores_gemma":[0.99979967,0.00002214263,0.000021845317,0.000113653194,0.000028874125,0.000013824234],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000038777875,0.000053358715,0.00006934624,0.000008140026,0.000050067327,0.000006853742,0.00004413352,0.00004291491,0.0000118643],"category_scores_gemma":[0.0000063885896,0.00003510195,0.000043091324,0.0000247879,0.000021536545,4.1799825e-7,0.000011970806,0.0000082556335,3.5406e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022263135,0.00005822475,0.0007753837,0.000021824802,0.00003075528,7.1190165e-8,0.000024536634,0.00002920755,0.9961152,0.000115957504,0.0003007203,0.0025058577],"study_design_scores_gemma":[0.00032234442,0.00034227056,0.00034548546,0.000004029131,0.00003001268,4.807355e-8,0.000023310844,0.00021820872,0.96457875,0.00012030442,0.033978947,0.00003626932],"about_ca_topic_score_codex":0.0000057403004,"about_ca_topic_score_gemma":0.000003795413,"teacher_disagreement_score":0.033678226,"about_ca_system_score_codex":0.0000036648614,"about_ca_system_score_gemma":0.000020194157,"threshold_uncertainty_score":0.1431416},"labels":[],"label_agreement":null},{"id":"W4412069751","doi":"10.1093/ijnp/pyaf045","title":"Efficacy and safety of the muscarinic receptor agonist KarXT (Xanomeline-Trospium) in schizophrenia: a systematic review, meta-analysis and Bayesian sensitivity analysis","year":2025,"lang":"en","type":"article","venue":"The International Journal of Neuropsychopharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Impact","funders":"","keywords":"Meta-analysis; Positive and Negative Syndrome Scale; Schizophrenia (object-oriented programming); Placebo; Adverse effect; Internal medicine; Medicine; Randomized controlled trial; Nausea; Psychology; Psychiatry; Psychosis","score_opus":0.012087640585269009,"score_gpt":0.3006260180902946,"score_spread":0.2885383775050256,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412069751","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97064716,0.017330157,0.0047757775,0.0059931907,0.0006472307,0.000513644,0.000039268078,0.0000025377947,0.00005103359],"genre_scores_gemma":[0.99306566,0.004668153,0.0001823883,0.0018950008,0.00006715737,0.000008681661,0.0000049169817,0.000007064197,0.0001010017],"study_design_codex":"bench_or_experimental","study_design_gemma":"meta_analysis","domain_scores_codex":[0.9976626,0.00088867336,0.000864069,0.00022842376,0.00024428082,0.000111948975],"domain_scores_gemma":[0.99843705,0.00024761786,0.0007300943,0.00024595385,0.00029720817,0.00004209809],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015485454,0.00015366968,0.0009059373,0.00028960148,0.000058879425,0.000026225725,0.00043733077,0.00006170244,0.00006886575],"category_scores_gemma":[0.00030279814,0.00008779243,0.000751639,0.00063094666,0.00011473566,0.000007487646,0.00018754564,0.00023972258,2.897815e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013527122,0.0001526667,0.0008208359,0.0010304785,0.1167207,0.000019200075,0.000057148227,0.0017501778,0.87751365,0.00012071199,0.00021858752,0.0002431194],"study_design_scores_gemma":[0.011430778,0.0007593664,0.04976216,0.0019078328,0.8048117,0.0004607771,0.00018846539,0.0055682585,0.1228578,0.0003723213,0.0010725842,0.000807962],"about_ca_topic_score_codex":0.000019928246,"about_ca_topic_score_gemma":0.000049665105,"teacher_disagreement_score":0.75465584,"about_ca_system_score_codex":0.00001802308,"about_ca_system_score_gemma":0.00006037267,"threshold_uncertainty_score":0.35800716},"labels":[],"label_agreement":null},{"id":"W4412492277","doi":"10.1021/acschemneuro.5c00280","title":"A Structure–Activity Relationship Study of Novel Positive Allosteric Modulators for the δ-Opioid Receptor","year":2025,"lang":"en","type":"article","venue":"ACS Chemical Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"National Health and Medical Research Council","keywords":"Allosteric regulation; Functional selectivity; Addiction; Chronic pain; Allosteric modulator; μ-opioid receptor; Opioid; Opioid receptor; Pharmacology; Depression (economics); Medicine; Neuroscience; Receptor; Psychology; G protein-coupled receptor; Internal medicine","score_opus":0.0207104759258174,"score_gpt":0.2811608677681856,"score_spread":0.2604503918423682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412492277","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9803131,0.000029049537,0.018752825,0.00008797294,0.0002991306,0.00045983,0.00003288715,0.000005799191,0.000019411134],"genre_scores_gemma":[0.999116,0.000003943722,0.00046877496,0.0002303058,0.000039956336,0.000028649582,0.000006092733,0.0000074607196,0.00009883449],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991687,0.000025536021,0.00015152074,0.00036250087,0.00013585285,0.00015589176],"domain_scores_gemma":[0.99942297,0.00011428663,0.00008030004,0.0002754539,0.000074376745,0.000032623328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012223923,0.00010644943,0.00010996079,0.00002515798,0.00013904771,0.000022516111,0.00032179838,0.00007256962,0.0000024013987],"category_scores_gemma":[0.00045688415,0.00007831697,0.000053739008,0.00022785648,0.00010218741,0.000006615567,0.00014666458,0.00009348654,1.0282885e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006947041,0.0001484096,0.00081555895,0.0000066282105,0.0000067184014,5.3095242e-8,0.000058477828,0.00013991143,0.9980297,0.00020908253,0.000058097474,0.00045789854],"study_design_scores_gemma":[0.00043501565,0.00022927305,0.0039313566,0.0000066315674,0.00001689352,0.0000010176062,0.00006771204,0.0010295566,0.9938749,0.00010790692,0.00021996126,0.00007978472],"about_ca_topic_score_codex":0.000010591796,"about_ca_topic_score_gemma":0.000002028911,"teacher_disagreement_score":0.018802887,"about_ca_system_score_codex":0.0000098785595,"about_ca_system_score_gemma":0.00004543107,"threshold_uncertainty_score":0.31936732},"labels":[],"label_agreement":null},{"id":"W4412493880","doi":"10.1371/journal.pone.0320114","title":"Optimization of the prostaglandin F2α receptor for structural biology","year":2025,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Receptor; G protein-coupled receptor; Heterotrimeric G protein; Signal transduction; Biology; Cell biology; Structural biology; Biochemistry; Ligand (biochemistry); Protein structure; G protein; Biophysics","score_opus":0.017886262561188533,"score_gpt":0.2407378974665224,"score_spread":0.22285163490533388,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412493880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97574025,0.0003262092,0.022881126,0.00019524491,0.0001590336,0.00046601015,0.00006171145,0.0000060773073,0.00016431737],"genre_scores_gemma":[0.97931993,0.000063176834,0.019352421,0.000104191655,0.00009234508,0.00004118737,0.00016205004,0.0000080227,0.0008566989],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995991,0.000025002832,0.00011748707,0.00012969106,0.000038576978,0.00009012828],"domain_scores_gemma":[0.99969107,0.000009420038,0.00005745107,0.00014395473,0.000086740125,0.000011356904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006761731,0.00005704497,0.00009372073,0.00001687065,0.000054584216,0.0000054460434,0.00011105543,0.00008677488,0.00004307489],"category_scores_gemma":[0.00009638113,0.00004008557,0.00004821997,0.000054957804,0.00002863487,0.0000011092047,0.000047255744,0.000028375609,2.7820494e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052368396,0.000037468373,0.0013801478,0.00003984897,0.00007935465,3.9450585e-9,0.000012933629,0.00028746107,0.99686486,0.00082811614,0.00021332012,0.00020414722],"study_design_scores_gemma":[0.00030207247,0.00011598789,0.00005302136,0.0000335479,0.000028043947,6.3354e-8,0.00001569904,0.0014316244,0.9969927,0.00042069666,0.0005584155,0.000048124177],"about_ca_topic_score_codex":0.0000028159666,"about_ca_topic_score_gemma":0.0000018597294,"teacher_disagreement_score":0.0035796363,"about_ca_system_score_codex":0.000005624631,"about_ca_system_score_gemma":0.00003108803,"threshold_uncertainty_score":0.16346422},"labels":[],"label_agreement":null},{"id":"W4412726703","doi":"10.1111/dom.16660","title":"Evaluating biased agonism of glucagon‐like peptide‐1 ( <scp>GLP</scp> ‐1) receptors to improve cellular bioenergetics: A systematic review","year":2025,"lang":"en","type":"review","venue":"Diabetes Obesity and Metabolism","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Medicine; Agonism; Glucagon-like peptide-1; Receptor; Bioenergetics; Exenatide; Pharmacology; Endocrinology; Internal medicine; Cell biology; Diabetes mellitus; Type 2 diabetes; Biology","score_opus":0.01946024597199198,"score_gpt":0.294103723815944,"score_spread":0.27464347784395204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412726703","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0059476397,0.98896646,0.00026730783,0.000007953617,0.0012257033,0.0032593193,0.00021652495,0.000028983712,0.00008007427],"genre_scores_gemma":[0.00007303391,0.9937402,0.0022090222,0.0004455059,0.00030939665,0.0006130554,0.0005930441,0.00008899579,0.001927749],"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","domain_scores_codex":[0.9950394,0.0009745174,0.0016639628,0.0011502433,0.00047325875,0.00069864234],"domain_scores_gemma":[0.99680835,0.0002999429,0.0010816023,0.0011157641,0.000364064,0.00033030126],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002381265,0.00090395607,0.0043145902,0.00031827454,0.00018339125,0.00008234589,0.0007030046,0.00068790617,0.000025513893],"category_scores_gemma":[0.0025140878,0.0007488469,0.0011362839,0.0005433893,0.000085976055,0.00001115509,0.00051548064,0.00034332095,0.000019778065],"study_design_candidate":"systematic_review","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000014528902,0.0001072111,0.0000021843891,0.9207495,0.00084189535,0.0000015548706,0.000060924962,0.0000031661502,0.04214207,0.00011818741,0.00086315966,0.035108726],"study_design_scores_gemma":[0.0004387228,0.00032930306,0.0000011897943,0.40960774,0.011328755,0.0000028148054,0.00006457867,0.000022975028,0.09049942,0.000076751596,0.48693165,0.0006960994],"about_ca_topic_score_codex":0.000014794003,"about_ca_topic_score_gemma":0.0000018188158,"teacher_disagreement_score":0.5111417,"about_ca_system_score_codex":0.00002840925,"about_ca_system_score_gemma":0.00037878967,"threshold_uncertainty_score":0.9994963},"labels":[],"label_agreement":null},{"id":"W4413037146","doi":"10.1101/2025.08.06.668689","title":"Sex-specific exploration accounts for differences in valence learning in male and female mice","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Douglas Mental Health University Institute; McGill University; McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Valence (chemistry); Psychology; Developmental psychology; Salience (neuroscience); Cognitive psychology; Chemistry","score_opus":0.022033519082799883,"score_gpt":0.23264977602850842,"score_spread":0.21061625694570854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413037146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9815057,0.0026198758,0.014738971,0.000041779243,0.000380797,0.000603987,0.00007512937,0.00002590946,0.000007867749],"genre_scores_gemma":[0.9931965,0.0025281033,0.0036799118,0.00004489393,0.00016360004,0.00029067873,0.0000026694065,0.000033198598,0.000060448314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99817353,0.00011141748,0.00037529768,0.0008753409,0.0001309306,0.0003334555],"domain_scores_gemma":[0.9992439,0.00003920489,0.00017761256,0.00033994598,0.00013474857,0.00006455071],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0005057508,0.0003150154,0.00036583657,0.00019527457,0.000082933846,0.00012544318,0.00026670098,0.00047211518,0.000011358755],"category_scores_gemma":[0.000110888934,0.00035576013,0.00006380003,0.00017359678,0.000042610467,0.000017804276,0.0002788937,0.0003576164,0.0000016580663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049679984,0.00004865226,0.03776971,0.00026973098,0.000020245014,0.000004065684,0.000030069814,0.0002317757,0.9613632,0.00016611714,0.000025828274,0.000020938474],"study_design_scores_gemma":[0.0007395621,0.000105451225,0.01671765,0.00059938553,0.000017142596,1.505863e-8,0.000064346335,0.0011359069,0.97670066,0.000012418978,0.003286615,0.0006208325],"about_ca_topic_score_codex":0.000028257173,"about_ca_topic_score_gemma":0.000022879512,"teacher_disagreement_score":0.021052059,"about_ca_system_score_codex":0.000046989233,"about_ca_system_score_gemma":0.00019348605,"threshold_uncertainty_score":0.99988943},"labels":[],"label_agreement":null},{"id":"W4413108930","doi":"10.1017/s109285292510045x","title":"Biased agonism in psychopharmacology: an opportunity to improve efficacy and safety of treatments","year":2025,"lang":"en","type":"review","venue":"CNS Spectrums","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta; University of Toronto; Brain and Cognition Discovery Foundation; University Health Network","funders":"","keywords":"Agonism; Psychopharmacology; Medicine; Psychology; Pharmacology; Psychotherapist; Psychiatry; Political science","score_opus":0.030023209256323805,"score_gpt":0.35666128644713746,"score_spread":0.32663807719081367,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413108930","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.011489092,0.9849204,0.00013843724,0.000036752997,0.00055236666,0.0016594408,0.00025611487,0.00001332082,0.0009341034],"genre_scores_gemma":[0.0010361818,0.9971867,0.0003711851,0.00013381886,0.00014311036,0.000087115375,0.0004096125,0.000033316846,0.0005989275],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983784,0.00016171265,0.00049391476,0.00061407924,0.00007899266,0.0002728923],"domain_scores_gemma":[0.9990836,0.000033017615,0.00018054282,0.00042337703,0.000024922188,0.00025456917],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00022372004,0.00034361577,0.0009176038,0.00018723606,0.000046154444,0.00001411442,0.00025210503,0.0003755841,0.00014204273],"category_scores_gemma":[0.00007753986,0.00030005036,0.00017966094,0.00018835378,0.00003927754,0.0000034517352,0.00012551468,0.00017250168,0.00000316453],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016587084,0.00028252706,0.0000043679543,0.0015107676,0.00023027879,0.000012700584,0.000025719997,0.0000022380223,0.04336236,0.000121267534,0.0001354336,0.95414644],"study_design_scores_gemma":[0.0039472706,0.0024822387,0.000066051645,0.004066087,0.0008745367,0.000019849478,0.00003705097,0.00000670826,0.025408855,0.00013140697,0.96201247,0.00094746734],"about_ca_topic_score_codex":0.000028234326,"about_ca_topic_score_gemma":0.000018233779,"teacher_disagreement_score":0.96187705,"about_ca_system_score_codex":0.00004581437,"about_ca_system_score_gemma":0.00040568667,"threshold_uncertainty_score":0.99994516},"labels":[],"label_agreement":null},{"id":"W4413226870","doi":"10.1021/acsmedchemlett.5c00354","title":"Terpene-Based Thiazole Hydrazines as Negative Allosteric Modulators of MRGPRX4: In Vitro Evaluation and Binding Site Analysis","year":2025,"lang":"en","type":"article","venue":"ACS Medicinal Chemistry Letters","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Agricultural Research Service","keywords":"Allosteric regulation; Thiazole; Terpene; In vitro; Binding site; Chemistry; Stereochemistry; Computational biology; Biochemistry; Combinatorial chemistry; Pharmacology; Biology; Enzyme","score_opus":0.00557615620928051,"score_gpt":0.2583332822025833,"score_spread":0.25275712599330274,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413226870","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99759626,0.00036614624,0.0010760763,0.0005716923,0.000051351195,0.0001350045,0.000010045566,0.000005246015,0.000188195],"genre_scores_gemma":[0.99852234,0.000023511777,0.00036104073,0.0006915825,0.00005369392,0.000021105023,0.00028030414,0.000009020742,0.00003742259],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887365,0.00005647848,0.0002865752,0.00035071262,0.00025449687,0.00017808654],"domain_scores_gemma":[0.999485,0.00003732668,0.0001362504,0.00021550378,0.00007386398,0.000052017265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040764012,0.00016308785,0.00026143732,0.00013435101,0.00004164917,0.000013682973,0.00012050334,0.00011571116,0.00005134025],"category_scores_gemma":[0.00012806444,0.0001557236,0.000083231535,0.00041616987,0.00008557989,0.0000062321956,0.000053997013,0.000101805876,7.179947e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014242277,0.000020090036,0.002873343,0.000069900656,0.00019111764,0.0000033300923,0.00008413367,0.0012946115,0.9944244,6.2527124e-7,0.000051615727,0.0008444012],"study_design_scores_gemma":[0.0008261356,0.000022960325,0.0007874188,0.000068424066,0.00033885005,0.0000017200886,0.00016223907,0.0035697743,0.9940112,0.000020438632,0.00005917581,0.00013161876],"about_ca_topic_score_codex":0.00008671794,"about_ca_topic_score_gemma":0.000007779612,"teacher_disagreement_score":0.0022751628,"about_ca_system_score_codex":0.00003515073,"about_ca_system_score_gemma":0.000076046344,"threshold_uncertainty_score":0.6350224},"labels":[],"label_agreement":null},{"id":"W4413304628","doi":"10.1101/2025.08.13.670154","title":"Computational design of allosteric pathways reprograms ligand-selective GPCR signaling","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"G protein-coupled receptor; Allosteric regulation; Computational biology; Functional selectivity; Drug discovery; Signal transduction; Ligand (biochemistry); Receptor; Biology; Agonist; Cell biology; Bioinformatics; Biochemistry","score_opus":0.017738475462059734,"score_gpt":0.22599516154001356,"score_spread":0.20825668607795383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413304628","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.70009756,0.0018014018,0.29608944,0.000023953044,0.00069997454,0.00094754796,0.00022380367,0.00010288557,0.000013419634],"genre_scores_gemma":[0.943664,0.00017027867,0.055514835,0.00011529433,0.0003081419,0.00013915486,0.000005183039,0.000073424424,0.0000096562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99713194,0.00023392362,0.00068601535,0.0011455424,0.00035255824,0.00045003247],"domain_scores_gemma":[0.997597,0.000060359856,0.0005558025,0.0007973031,0.00083755754,0.00015197662],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00070367526,0.0005258282,0.0005975388,0.00018646118,0.00013646341,0.00010301445,0.00053608435,0.00070469873,0.000019239342],"category_scores_gemma":[0.00018577617,0.00058151246,0.0002702314,0.00034313367,0.00008328792,0.00000821345,0.0005223906,0.0004251591,0.000005411515],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010381617,0.00013559025,0.00037191433,0.0002346871,0.00033539464,0.000008722103,0.000012918697,0.022077058,0.97627795,0.0003019624,0.00012835214,0.000011659513],"study_design_scores_gemma":[0.00044398577,0.00024965624,0.00036350297,0.00037342994,0.00010497913,2.950617e-8,0.0000069031007,0.0024029282,0.99509495,0.000029105982,0.00035955847,0.0005709698],"about_ca_topic_score_codex":0.00001892346,"about_ca_topic_score_gemma":3.6613977e-7,"teacher_disagreement_score":0.24356644,"about_ca_system_score_codex":0.000064974876,"about_ca_system_score_gemma":0.0009917489,"threshold_uncertainty_score":0.99966365},"labels":[],"label_agreement":null},{"id":"W4413308588","doi":"10.3390/cells14161284","title":"Decoding ADGRE5: How Proteolytic Cleavage and Mechanical Forces Unleash Cellular Signals","year":2025,"lang":"en","type":"article","venue":"Cells","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer; Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Mitacs","keywords":"Receptor; Chemistry; Signal transduction; Cell biology; Proteolysis; G protein-coupled receptor; Biology; Biochemistry","score_opus":0.0071496898248998705,"score_gpt":0.22195128011354937,"score_spread":0.2148015902886495,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413308588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9139486,0.001968505,0.08114514,0.0002530942,0.00037575146,0.00047302645,0.000007549427,0.000027709651,0.0018006017],"genre_scores_gemma":[0.99309975,0.0001853518,0.002173284,0.0002710608,0.00013152129,0.000022628616,0.000014457696,0.000018635954,0.0040833345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990553,0.000054101623,0.00015209618,0.00038376407,0.000095853386,0.00025885372],"domain_scores_gemma":[0.9995712,0.000020412683,0.000057943333,0.00022505078,0.000039574043,0.00008580132],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024334872,0.0001618985,0.00017419858,0.000045919343,0.00011532909,0.00008259903,0.00016054534,0.00018538779,0.00005457856],"category_scores_gemma":[0.000040895105,0.00014945383,0.00008292171,0.00007512401,0.000040078852,0.0000050047192,0.00014490217,0.000094732015,0.0000081459975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022144233,0.000025026984,0.00002136,0.000048579386,0.000033142995,0.0000035936528,0.000016379981,0.0000085040965,0.9948772,0.00072334934,0.0015915582,0.0026291301],"study_design_scores_gemma":[0.00044391965,0.00012738093,0.0000043543355,0.000047654983,0.000026449594,0.0000017671364,0.000108794695,0.0006035587,0.98536813,0.000885893,0.012214167,0.0001679331],"about_ca_topic_score_codex":0.000003695932,"about_ca_topic_score_gemma":0.0000027863468,"teacher_disagreement_score":0.0791511,"about_ca_system_score_codex":0.000009228339,"about_ca_system_score_gemma":0.000040038685,"threshold_uncertainty_score":0.60945505},"labels":[],"label_agreement":null},{"id":"W4413332430","doi":"10.1016/j.celrep.2025.116160","title":"Structural basis of peptide recognition and modulation for neuropeptide FF receptors","year":2025,"lang":"en","type":"article","venue":"Cell Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Program of Shanghai Academic Research Leader; China Postdoctoral Science Foundation; National Natural Science Foundation of China; Canadian Anesthesiologists' Society; Shanghai Lingjun Program","keywords":"Receptor; Neuropeptide; Peptide; Modulation (music); Neuropeptide Y receptor; G protein-coupled receptor; Chemistry; Cell biology; Neuroscience; Biology; Biochemistry; Physics","score_opus":0.014150185343291209,"score_gpt":0.23235346810853666,"score_spread":0.21820328276524545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413332430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939432,0.00017739831,0.0042035207,0.000016653035,0.00036632715,0.00020849044,0.000005942711,0.0000064150445,0.0010720405],"genre_scores_gemma":[0.99548006,0.000060691247,0.0028273866,0.00004570358,0.000063364525,0.0000136248755,0.00018961636,0.000010734406,0.0013088166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99934626,0.00001999611,0.00024400874,0.00024329746,0.000052107243,0.00009433627],"domain_scores_gemma":[0.9995656,0.000011039351,0.00014649409,0.00014573465,0.00010324254,0.00002786846],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014225036,0.00008196664,0.00010241226,0.00003810716,0.000049714898,0.000011571285,0.000027334132,0.000074855176,0.000028450017],"category_scores_gemma":[0.00008746971,0.00007937775,0.00005990775,0.000046149296,0.000020675416,0.000003866916,0.000029371704,0.000028461085,2.6122794e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031276868,0.000006962552,0.0012482662,0.000055147873,0.00001215814,0.0000013933874,0.00001798146,0.0001012063,0.9834846,0.000008847814,0.00066072063,0.0143714],"study_design_scores_gemma":[0.00016475879,0.000097422766,0.0009611007,0.000022188357,0.000021482578,0.000009532696,0.000036303867,0.0002959112,0.99236643,0.0013020498,0.00463499,0.0000878244],"about_ca_topic_score_codex":0.0000130028175,"about_ca_topic_score_gemma":0.0000033786014,"teacher_disagreement_score":0.014283576,"about_ca_system_score_codex":0.0000052026317,"about_ca_system_score_gemma":0.000027901782,"threshold_uncertainty_score":0.32369307},"labels":[],"label_agreement":null},{"id":"W4413447519","doi":"10.1007/s00210-025-04540-x","title":"Mapping the evolution of kainate receptor research over five decades: trends, hotspots, and emerging frontiers","year":2025,"lang":"en","type":"article","venue":"Naunyn-Schmiedeberg s Archives of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"China Postdoctoral Science Foundation; National Natural Science Foundation of China","keywords":"Evolutionary biology; Geography; Data science; Economic geography; Biology; Computational biology; Computer science","score_opus":0.014501407090997323,"score_gpt":0.3191787527052854,"score_spread":0.30467734561428805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413447519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96919787,0.011437768,0.012820346,0.001062456,0.00073492463,0.0003308004,0.000029034274,0.000011499027,0.004375301],"genre_scores_gemma":[0.9909376,0.0020725895,0.003058218,0.00014266033,0.00016609005,0.00004655738,0.00002355107,0.000019178075,0.0035335564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980832,0.0004945386,0.00040400983,0.00042575368,0.00018132152,0.00041121125],"domain_scores_gemma":[0.99925303,0.00018582259,0.00017351529,0.00021609188,0.00011137725,0.00006018262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068916206,0.00017964099,0.00029436938,0.00055649574,0.00023861742,0.000011643386,0.0003966431,0.00015309607,0.00012481146],"category_scores_gemma":[0.00007072392,0.00014904691,0.00013746807,0.0004668254,0.0005119187,0.000008364956,0.00033526504,0.00031115118,6.5649033e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043509473,0.00005687194,0.00069322385,0.00007871971,0.00027591016,8.2346764e-7,0.0006813605,0.00015125041,0.9577071,0.0027517027,0.014762919,0.022405012],"study_design_scores_gemma":[0.0014062027,0.00029796083,0.0027424903,0.00008508832,0.000056330082,0.0000021874132,0.0021784003,0.001818675,0.90197617,0.0022657246,0.08698016,0.00019060927],"about_ca_topic_score_codex":0.00015674022,"about_ca_topic_score_gemma":0.000016343756,"teacher_disagreement_score":0.07221724,"about_ca_system_score_codex":0.00003254393,"about_ca_system_score_gemma":0.00016597357,"threshold_uncertainty_score":0.60779566},"labels":[],"label_agreement":null},{"id":"W4413448456","doi":"10.1101/2025.08.13.670122","title":"Tunable Bias Signaling of the Angiotensin II Type 1 Receptor for Inotropy via C-Terminal Peptide Modifications and Allosteric Site Targeting","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; Université de Sherbrooke","funders":"","keywords":"Allosteric regulation; Terminal (telecommunication); Receptor; Chemistry; Peptide; Angiotensin II; Cell biology; Biochemistry; Biology; Computer science; Telecommunications","score_opus":0.017311971923916238,"score_gpt":0.22648344654755304,"score_spread":0.2091714746236368,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413448456","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9839695,0.0017664055,0.012220404,0.00011551482,0.0008009686,0.00078123965,0.0003074108,0.00003434178,0.0000042311312],"genre_scores_gemma":[0.96927595,0.00022107213,0.029759776,0.00013774492,0.0003768109,0.00008096931,0.0000062684835,0.00006114824,0.000080277874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980568,0.00011976494,0.00052370765,0.00075324456,0.00017885162,0.00036761773],"domain_scores_gemma":[0.9979128,0.000046734214,0.00048126013,0.00075594516,0.0006998557,0.000103406164],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00047599725,0.0003794634,0.00040725805,0.00010243861,0.00034032925,0.00007377206,0.00040102485,0.00046229604,0.00001802758],"category_scores_gemma":[0.00030760217,0.00034598092,0.00021876257,0.00025107746,0.000098548626,0.000009248748,0.0007243226,0.0002757634,0.0000015945039],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006279384,0.00004701233,0.000635674,0.00023492932,0.00011767212,6.339289e-7,0.000018631503,0.00040308543,0.9978077,0.00011940697,0.00054835674,0.000004142905],"study_design_scores_gemma":[0.00027737863,0.00011587446,0.00060009473,0.0002943354,0.00012562911,2.877972e-8,0.0000066640805,0.001095037,0.9884861,0.000004902743,0.008613796,0.00038015473],"about_ca_topic_score_codex":0.00004201755,"about_ca_topic_score_gemma":0.0000018678554,"teacher_disagreement_score":0.01753937,"about_ca_system_score_codex":0.000039790542,"about_ca_system_score_gemma":0.00040075302,"threshold_uncertainty_score":0.9998992},"labels":[],"label_agreement":null},{"id":"W4413449430","doi":"10.1016/j.neuropharm.2025.110654","title":"Positive allosteric modulation of M1 mAChRs with VU0486846 reverses cognitive deficits in male APPswe/PSEN1ΔE9 alzheimer's mice","year":2025,"lang":"en","type":"article","venue":"Neuropharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; University of Ottawa","funders":"Canadian Institutes of Health Research; Krembil Foundation; Michael Smith Health Research BC; Alzheimer Society","keywords":"Allosteric regulation; Neuroscience; Medicine; Cognition; Psychology; Pharmacology; Internal medicine; Receptor","score_opus":0.010640453009775189,"score_gpt":0.2693342152490015,"score_spread":0.2586937622392263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413449430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959041,0.0005777885,0.0012547075,0.000086602726,0.00024375695,0.0003880933,0.000029638522,0.000007935681,0.0015074096],"genre_scores_gemma":[0.9982537,0.00014793084,0.0003128091,0.0008819424,0.00004758874,0.000032297576,0.00006377277,0.000019330559,0.00024064547],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9988789,0.00019436488,0.00023717365,0.0003838027,0.000082650135,0.00022312264],"domain_scores_gemma":[0.999542,0.00006701279,0.00011893963,0.000097171825,0.00013654576,0.000038354832],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008581295,0.0001653446,0.00021596724,0.000122028556,0.00004221528,0.000006968525,0.00011964,0.00012104154,0.00010834097],"category_scores_gemma":[0.0000323397,0.00016120361,0.00005139713,0.00021912107,0.00008238078,0.000006431553,0.00008654915,0.0001274963,0.0000051095385],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00087879074,0.00009998472,0.0014442139,0.00002111594,0.00013616566,0.000038067436,0.000048765432,0.0006751148,0.9944213,0.00006350894,0.00013481267,0.0020381738],"study_design_scores_gemma":[0.0017490134,0.0006614423,0.0064464062,0.000048785485,0.00014866202,0.000032961532,0.00011426972,0.0005888444,0.9895906,0.000022563367,0.00042651372,0.00016996045],"about_ca_topic_score_codex":0.00004100879,"about_ca_topic_score_gemma":0.00002003648,"teacher_disagreement_score":0.005002192,"about_ca_system_score_codex":0.000010817201,"about_ca_system_score_gemma":0.00007670803,"threshold_uncertainty_score":0.65736926},"labels":[],"label_agreement":null},{"id":"W4413470134","doi":"10.1101/2025.08.19.671074","title":"GPC5 expression highlights astrocytic heterogeneity and divergent hippocampal responses in Alzheimer’s and Parkinson’s Dementia","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Hippocampal formation; Dementia; Neuroscience; Parkinson's disease; Expression (computer science); Psychology; Medicine; Internal medicine; Computer science; Disease","score_opus":0.01642431728859749,"score_gpt":0.23916774312672037,"score_spread":0.22274342583812287,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413470134","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9787802,0.018995073,0.00097108295,0.000050559906,0.0005541383,0.00046203873,0.000145918,0.00003853732,0.000002456866],"genre_scores_gemma":[0.99219793,0.0029080806,0.0044606356,0.00009926907,0.00018213052,0.00010459392,0.0000018510614,0.000041656273,0.0000038769517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975473,0.00025624668,0.00043404568,0.0011270479,0.00020861729,0.0004267248],"domain_scores_gemma":[0.9987856,0.000025675014,0.00021556881,0.00063863804,0.00011911927,0.00021541191],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042989742,0.0004791138,0.00042596913,0.00018770585,0.00015585194,0.00012577805,0.00027663255,0.0005596382,0.000020134697],"category_scores_gemma":[0.00007754448,0.000489013,0.00009363077,0.000107470085,0.0000823161,0.000010634663,0.0010491445,0.00030884586,0.0000019846188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017518044,0.000059654398,0.02010985,0.00012343511,0.00024257798,0.000016441196,0.0000069051894,0.000027805603,0.9790774,0.00006156234,0.00009268281,0.000006487166],"study_design_scores_gemma":[0.000598691,0.000091635055,0.037467036,0.0003311646,0.00016610348,3.568816e-8,0.0000030973479,0.00010400081,0.9546412,0.000002564886,0.006109917,0.0004845387],"about_ca_topic_score_codex":0.000039861825,"about_ca_topic_score_gemma":0.000019632767,"teacher_disagreement_score":0.024436202,"about_ca_system_score_codex":0.000039226306,"about_ca_system_score_gemma":0.00026236457,"threshold_uncertainty_score":0.99975616},"labels":[],"label_agreement":null},{"id":"W4414011109","doi":"10.1101/2025.09.01.673498","title":"Next generation neural mass model with dopamine modulation mediated by D1-type receptors","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Agence Nationale de la Recherche","keywords":"Receptor; Dopamine receptor; Dopamine; Neuroscience; Modulation (music); Computer science; Chemistry; Psychology; Physics; Biochemistry","score_opus":0.01756367277377933,"score_gpt":0.21753161050135647,"score_spread":0.19996793772757715,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414011109","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9252438,0.0012553713,0.07116701,0.00012446313,0.0012166477,0.00062296697,0.00023539053,0.00012432312,0.0000100421275],"genre_scores_gemma":[0.98583144,0.00049673603,0.012497991,0.00023740897,0.0005659657,0.00009533638,0.00006790023,0.00010203491,0.0001051708],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975217,0.00012592529,0.00046499074,0.0011139971,0.00033852467,0.00043486632],"domain_scores_gemma":[0.9979798,0.000012111642,0.00033881734,0.00087070523,0.00061075424,0.0001878011],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00029152987,0.00056801754,0.00041317916,0.00014302263,0.00016217022,0.00021859774,0.0003834547,0.0007706466,0.000043066142],"category_scores_gemma":[0.0001082809,0.0005628224,0.000110005596,0.00030517197,0.00005709547,0.00002208146,0.00021843458,0.00041842106,0.000007410466],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008128878,0.000048617432,0.0003566263,0.000075229604,0.00012231196,0.0000024349254,0.0000026294235,0.027782362,0.97007686,0.00006332209,0.0013828239,0.0000055217834],"study_design_scores_gemma":[0.00041265323,0.00012666402,0.000082341154,0.000073356896,0.000067532674,9.445853e-9,0.0000015874496,0.22043309,0.7759355,0.0000010070984,0.0022874074,0.0005788688],"about_ca_topic_score_codex":0.000026145146,"about_ca_topic_score_gemma":0.0000038434364,"teacher_disagreement_score":0.19414134,"about_ca_system_score_codex":0.00008803597,"about_ca_system_score_gemma":0.0004835149,"threshold_uncertainty_score":0.9996823},"labels":[],"label_agreement":null},{"id":"W4414061620","doi":"10.1016/j.celrep.2025.116255","title":"Multimode neural population coding of diverse innate fear response by mitral and tufted cells","year":2025,"lang":"en","type":"article","venue":"Cell Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of Education and Child Care","funders":"National Key Research and Development Program of China; Nanjing Medical University; National Natural Science Foundation of China","keywords":"Calcium imaging; ENCODE; Olfactory bulb; Population; Optogenetics; Innate immune system; Neural coding","score_opus":0.006035119617433064,"score_gpt":0.23305146901341983,"score_spread":0.22701634939598678,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414061620","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9982731,0.00040226322,0.00081550557,0.000018020733,0.00021953566,0.000105546584,0.0000069152675,0.0000068171353,0.00015229339],"genre_scores_gemma":[0.99805516,0.00004480125,0.000463648,0.000047377045,0.0000131153665,0.000002462045,0.000060361115,0.000007681335,0.0013054163],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99931854,0.000054704284,0.00021898546,0.00022782819,0.00006740304,0.000112560265],"domain_scores_gemma":[0.99962574,0.00001137703,0.00012535222,0.00015892112,0.000041391682,0.0000372312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022207011,0.000084864274,0.00010814564,0.000037542777,0.000051257848,0.000012324792,0.000034660614,0.00009492724,0.000014643244],"category_scores_gemma":[0.0000447804,0.000084204934,0.000057299025,0.00005009623,0.000022280548,0.0000034212271,0.000056546272,0.00004578947,2.1406942e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015927706,0.00001933052,0.004245381,0.000020603668,0.000011757658,0.00001539888,0.000031423482,0.00013201825,0.994184,0.0000028297754,0.00072456844,0.00045336783],"study_design_scores_gemma":[0.00021423682,0.00005912495,0.0021289694,0.000014783563,0.000015938147,0.000006311511,0.000052447118,0.00070511363,0.9952637,0.000028864259,0.0014278357,0.00008265593],"about_ca_topic_score_codex":0.000087943394,"about_ca_topic_score_gemma":0.0000029019523,"teacher_disagreement_score":0.0021164117,"about_ca_system_score_codex":0.0000075442463,"about_ca_system_score_gemma":0.000019652825,"threshold_uncertainty_score":0.34337774},"labels":[],"label_agreement":null},{"id":"W4414082537","doi":"10.1097/aln.0000000000005600","title":"Current and Developing Approaches for Facilitating Emergence from General Anesthesia","year":2025,"lang":"en","type":"review","venue":"Anesthesiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institute on Aging","keywords":"Anesthetic; Narrative review; Leverage (statistics); Process (computing); MEDLINE","score_opus":0.07666001243247755,"score_gpt":0.3279886395356645,"score_spread":0.25132862710318693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414082537","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0058724685,0.98796433,0.0052741505,0.000012800171,0.00017020541,0.00064726634,0.000032883767,0.000015494115,0.000010382215],"genre_scores_gemma":[0.000060194932,0.98669416,0.011006203,0.00008234821,0.00035845666,0.00040802293,0.0012399757,0.000036916575,0.00011373269],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99802727,0.0002299365,0.0004987726,0.000832746,0.000060881222,0.00035040162],"domain_scores_gemma":[0.99917394,0.00019078547,0.00022057327,0.0003041009,0.000048223887,0.00006239977],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00025892878,0.00042828268,0.0010143837,0.00008175694,0.000140661,0.00002245318,0.0002958881,0.00051635137,0.000013888861],"category_scores_gemma":[0.0001310729,0.00036023726,0.0002913193,0.000082733684,0.00006821906,0.000002815641,0.00007992065,0.00014655328,0.0000037534396],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011118973,0.000011453084,0.000033183824,0.0036201489,0.0000856906,0.0000031800437,0.000037660706,0.0000033805081,0.00013947337,0.00071158714,0.0003605468,0.9949826],"study_design_scores_gemma":[0.00011359135,0.00013049714,0.000012032998,0.0014666966,0.00018275985,0.00003805782,0.000042069103,0.000021937376,0.00025684855,0.0006183837,0.99667174,0.00044539745],"about_ca_topic_score_codex":0.000014580699,"about_ca_topic_score_gemma":0.000004039651,"teacher_disagreement_score":0.9963112,"about_ca_system_score_codex":0.00001292872,"about_ca_system_score_gemma":0.00028824183,"threshold_uncertainty_score":0.99988496},"labels":[],"label_agreement":null},{"id":"W4414098391","doi":"10.1101/2025.09.09.671438","title":"Teneurin-4 switches between self-recognition and canonical Latrophilin binding to direct neuronal migration","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Cell migration; Cell adhesion; Process (computing); HEK 293 cells; Plasma protein binding; Neuronal migration; Adhesion; Mutant","score_opus":0.01521672432207108,"score_gpt":0.22096973868809341,"score_spread":0.20575301436602234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414098391","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964345,0.00040460713,0.0011820955,0.00017394418,0.0005473053,0.000555308,0.00056822825,0.00012164185,0.000012350454],"genre_scores_gemma":[0.9931295,0.00042022645,0.0051340903,0.00019113626,0.00092319865,0.00010923364,0.000011141443,0.000066684996,0.000014772671],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997658,0.00012675127,0.0004377756,0.0011254906,0.00023573819,0.000416248],"domain_scores_gemma":[0.9987077,0.000036878027,0.00019402814,0.0005477436,0.0002431589,0.00027049996],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00038032958,0.0004628186,0.00043442645,0.00021194768,0.00016516722,0.00017145577,0.0002919388,0.00060553855,0.000016634034],"category_scores_gemma":[0.00015751997,0.0005076148,0.0001433817,0.00021312147,0.000033713546,0.000009619625,0.00056228245,0.00040299215,0.000017005355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030160114,0.000042371597,0.0070584663,0.00014509588,0.00017403894,0.0000040640134,0.000006623306,0.000048208523,0.99234575,0.000012988798,0.000116165924,0.000016093963],"study_design_scores_gemma":[0.0002839593,0.0001556018,0.014525513,0.00020699136,0.0001883128,1.9532354e-8,0.0000019195274,0.000052132757,0.97872347,0.0000028314425,0.0052614026,0.000597832],"about_ca_topic_score_codex":0.000062171675,"about_ca_topic_score_gemma":0.000014876799,"teacher_disagreement_score":0.013622238,"about_ca_system_score_codex":0.00006482249,"about_ca_system_score_gemma":0.00044637828,"threshold_uncertainty_score":0.99973756},"labels":[],"label_agreement":null},{"id":"W4414109894","doi":"10.1146/annurev-pharmtox-062124-015046","title":"Incretin Signaling Neighborhoods and Adverse Drug Reactions","year":2025,"lang":"en","type":"review","venue":"The Annual Review of Pharmacology and Toxicology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Science for Life Laboratory; Vetenskapsrådet; Novo Nordisk Fonden; Svenska Sällskapet för Medicinsk Forskning; Cancerfonden; Eli Lilly and Company; European Foundation for the Study of Diabetes; Robert Bosch Stiftung; European Commission; Novo Nordisk; Diamond Light Source; McGill University; European Federation of Pharmaceutical Industries and Associations; Kungliga Tekniska Högskolan","keywords":"Incretin; Drug; Type 2 diabetes; Receptor; Drug reaction; Functional selectivity; Adverse effect; Action (physics)","score_opus":0.012266978394967355,"score_gpt":0.34052635612613696,"score_spread":0.3282593777311696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414109894","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001343932,0.9972057,0.000049084396,0.00035705414,0.0004671202,0.0009529398,0.00011372643,0.000009269606,0.00071076077],"genre_scores_gemma":[0.00018720781,0.99629605,0.00011946994,0.001854356,0.00028201312,0.00018015859,0.00010620628,0.000023364431,0.0009511788],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99735314,0.0010580977,0.0007427692,0.0004783755,0.00007841218,0.00028920767],"domain_scores_gemma":[0.99861795,0.00042234862,0.0005199676,0.00024099328,0.000120879755,0.00007787358],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012368133,0.00036975805,0.0013528494,0.00009654305,0.00017858643,0.0000052717387,0.00033307556,0.00038620242,0.0002904933],"category_scores_gemma":[0.00021292262,0.0002540543,0.00030318825,0.00018029238,0.00031570034,0.0000062083272,0.00041257715,0.00043878684,0.0000046270693],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008395567,0.0001467769,0.0000031276966,0.17978927,0.0013968277,0.000017580705,0.00011588417,0.0000019465506,0.012688816,0.0023541877,0.024093168,0.77930844],"study_design_scores_gemma":[0.0002218039,0.00018178776,5.7873e-7,0.011694207,0.0017682837,0.00009333862,0.00005229114,9.985164e-7,0.0013749503,0.00007237011,0.9843177,0.00022164924],"about_ca_topic_score_codex":0.000007015169,"about_ca_topic_score_gemma":0.0000021296605,"teacher_disagreement_score":0.96022457,"about_ca_system_score_codex":0.00001281602,"about_ca_system_score_gemma":0.0002877575,"threshold_uncertainty_score":0.9999912},"labels":[],"label_agreement":null},{"id":"W4414272757","doi":"10.1016/j.neuron.2025.07.023","title":"Branch logic: Dendritic computations diversify inhibition","year":2025,"lang":"en","type":"letter","venue":"Neuron","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research","keywords":"Parvalbumin; Synapse; Inhibitory postsynaptic potential; Computation; Biological neural network; Somatostatin","score_opus":0.01434047940892664,"score_gpt":0.24096044489570076,"score_spread":0.22661996548677413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414272757","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.07988401,0.002106406,0.11295872,0.76936686,0.009919004,0.0019057358,0.00081864203,0.000277665,0.022762964],"genre_scores_gemma":[0.085629016,0.0002286734,0.0006284836,0.8952725,0.0040540146,0.000033090953,0.005026155,0.00005796837,0.009070099],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989524,0.00008620971,0.00016402958,0.00042738114,0.00014803663,0.00022196476],"domain_scores_gemma":[0.9995784,0.000021862932,0.00007093125,0.0002301612,0.00007207489,0.000026541224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000041133466,0.00019493303,0.0001594036,0.00007193173,0.00011538189,0.000044857898,0.00013249174,0.0005576693,0.0001288394],"category_scores_gemma":[0.000030345263,0.00020641394,0.0001379173,0.0000659235,0.000030228439,0.000002135085,0.000106311476,0.00048165233,0.000032884825],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005957245,0.000012084588,0.0000075208677,0.00007867532,0.000020971358,0.000046138182,0.000006767449,0.000082695864,0.11825456,0.00005314831,0.88079584,0.000635662],"study_design_scores_gemma":[0.0002804534,0.00017862803,0.000030654362,0.000068671085,0.000050936767,0.000016805816,0.000004743227,0.000040676812,0.06075705,0.0007538013,0.9375545,0.00026309976],"about_ca_topic_score_codex":0.000009198539,"about_ca_topic_score_gemma":0.000002439485,"teacher_disagreement_score":0.12590565,"about_ca_system_score_codex":0.000014584674,"about_ca_system_score_gemma":0.000054102373,"threshold_uncertainty_score":0.8417316},"labels":[],"label_agreement":null},{"id":"W4414484989","doi":"10.1016/j.cryobiol.2025.105319","title":"Interrupted slow cooling of mouse cardiac endothelial cell monolayers","year":2025,"lang":"en","type":"article","venue":"Cryobiology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Cryopreservation; Monolayer; Intracellular; Endothelial stem cell; Dimethyl sulfoxide; Endothelium; Viability assay; Hydroxyethyl starch; Substrate (aquarium)","score_opus":0.006143843101182644,"score_gpt":0.2330021233918676,"score_spread":0.22685828029068494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414484989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882039,0.0009976248,0.0074723903,0.000021882215,0.0007119724,0.00013226256,0.00004713451,0.000013380054,0.0023994585],"genre_scores_gemma":[0.9960689,0.00018860977,0.0007649573,0.00015694913,0.00010739189,0.000013928152,0.00008395991,0.000012965101,0.002602329],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991599,0.00008307255,0.0002350077,0.00027627216,0.00003254039,0.00021321423],"domain_scores_gemma":[0.9995364,0.000020401241,0.000079822785,0.00025606112,0.000072977564,0.00003436484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014307298,0.00012972244,0.00023672762,0.000066225686,0.000041844367,0.0000064402166,0.0001926854,0.0002259611,0.000053352316],"category_scores_gemma":[0.000047966936,0.00012184649,0.00014578432,0.00006597,0.000070303075,0.0000015128923,0.00011144424,0.00008730856,0.000007568962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012709634,0.00002885151,0.0005985582,0.000019686253,0.00006607826,4.7117373e-7,0.000035360757,0.00008567676,0.9969649,0.0002868412,0.0009062638,0.0008802243],"study_design_scores_gemma":[0.00037552437,0.00017301322,0.000044999237,0.000009255536,0.000019712828,7.5681794e-7,0.0001298609,0.000057479898,0.97386575,0.000058122605,0.025159432,0.000106071464],"about_ca_topic_score_codex":0.000029849765,"about_ca_topic_score_gemma":0.0000031477782,"teacher_disagreement_score":0.024253167,"about_ca_system_score_codex":0.000010448231,"about_ca_system_score_gemma":0.00006715558,"threshold_uncertainty_score":0.49687555},"labels":[],"label_agreement":null},{"id":"W4414593663","doi":"10.5194/egusphere-2025-4352-ac1","title":"Authors&amp;amp;#8217; preliminary reply to RC1 (Maarten G. Kleinhans)","year":2025,"lang":"nl","type":"peer-review","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Froude number; Planform; Hydraulics; Hydrology (agriculture); Sediment transport; Floodplain; Bank erosion; Reynolds number; Flow conditions","score_opus":0.028447577403722602,"score_gpt":0.3158828251150686,"score_spread":0.287435247711346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414593663","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005237313,0.4128307,0.23384818,0.23058368,0.019230872,0.008443377,0.0031081236,0.0003244187,0.09110691],"genre_scores_gemma":[0.00014942962,0.041560568,0.031892825,0.052983657,0.0016065931,0.00038066594,0.009955567,0.00015954657,0.86131114],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9923642,0.00057633704,0.00195713,0.0028049764,0.00085897837,0.0014383479],"domain_scores_gemma":[0.9945676,0.000086604196,0.00066816906,0.0029774753,0.0008200279,0.0008801487],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow","insufficient_payload"],"category_scores_codex":[0.001967494,0.0014895498,0.0020490375,0.00031401418,0.0004324147,0.00021885872,0.0015987202,0.0014402072,0.01655293],"category_scores_gemma":[0.0009445484,0.0014044376,0.0013229661,0.0006500894,0.00009550416,0.000009097864,0.0014652573,0.00094731286,0.0027292168],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001419168,0.00017486567,0.0000018890197,0.0034734684,0.0005000408,0.000010067576,0.00006699292,0.000051786286,0.040800463,0.00012922766,0.922975,0.0316743],"study_design_scores_gemma":[0.00038600276,0.00094319676,0.0000024852852,0.0068977564,0.0004461763,0.000048571983,0.0000466638,0.000024232693,0.02162598,0.00009683694,0.9680128,0.0014692682],"about_ca_topic_score_codex":0.00045107194,"about_ca_topic_score_gemma":0.00017594795,"teacher_disagreement_score":0.77020425,"about_ca_system_score_codex":0.00015125025,"about_ca_system_score_gemma":0.0013509885,"threshold_uncertainty_score":0.9998561},"labels":[],"label_agreement":null},{"id":"W4414619067","doi":"10.20944/preprints202509.2326.v1","title":"Sex-Specific Effects of the β3-Adrenergic Receptor Agonist Mirabegron in a Murine Two-Hit Heart Failure Model with Preserved Ejection Fraction","year":2025,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval","keywords":"Mirabegron; Heart failure with preserved ejection fraction; Ejection fraction; Heart failure; Brown adipose tissue; Muscle hypertrophy; Agonist","score_opus":0.030658067100887774,"score_gpt":0.2821124069040038,"score_spread":0.25145433980311604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414619067","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932759,0.0003690648,0.003780546,0.00017611649,0.0005305275,0.0011281766,0.00002658983,0.00003379076,0.0006793327],"genre_scores_gemma":[0.9950445,0.0002535556,0.0014467374,0.000049551756,0.00019898053,0.00032584017,0.00015338979,0.00004507576,0.00248236],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974217,0.0003208578,0.00050292246,0.0010992505,0.00032629684,0.0003289781],"domain_scores_gemma":[0.99802625,0.000031387328,0.00036093497,0.0013464335,0.00016406774,0.00007091701],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045893362,0.00042542262,0.0005057477,0.00012312908,0.000117032374,0.000026906624,0.0005549822,0.000546683,0.00011020826],"category_scores_gemma":[0.00008012006,0.00034878592,0.00028079076,0.00019869649,0.00008007408,0.000009960167,0.0011085046,0.0007612434,0.000010324861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002626833,0.00019250045,0.05667224,0.00040028698,0.00011059948,8.1517743e-7,0.000064663356,0.06314707,0.878891,0.0000622426,0.000114265276,0.00008163431],"study_design_scores_gemma":[0.0009178177,0.0000843064,0.0070698536,0.00055372814,0.000044840413,0.0000022119934,0.00005620384,0.0020129688,0.9856,0.00031019677,0.003003327,0.0003445226],"about_ca_topic_score_codex":0.00035965012,"about_ca_topic_score_gemma":0.00021295386,"teacher_disagreement_score":0.10670902,"about_ca_system_score_codex":0.00012272326,"about_ca_system_score_gemma":0.00024416167,"threshold_uncertainty_score":0.9998964},"labels":[],"label_agreement":null},{"id":"W4414823164","doi":"10.1016/j.jmccpl.2025.100486","title":"Quantification of morphological, functional, and biochemical features of H9c2 rat cardiomyoblast retinoic acid differentiation","year":2025,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology Plus","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Victoria","funders":"Canadian Institutes of Health Research; University of Victoria","keywords":"Retinoic acid; Context (archaeology); Cellular differentiation; Cytoskeleton; Cell culture; Cell; Actin cytoskeleton; Limiting","score_opus":0.008621817533218912,"score_gpt":0.21786252716303678,"score_spread":0.20924070962981786,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414823164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.867592,0.019572865,0.1123655,0.000060287453,0.00022426916,0.00007650423,0.0000055036644,0.0000017282002,0.00010138513],"genre_scores_gemma":[0.99837273,0.0008664417,0.00054351153,0.000039374285,0.00007671765,0.000002500653,0.000045346147,0.000007482953,0.000045890523],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989776,0.00017241207,0.0004010764,0.00020430076,0.00013200034,0.00011258897],"domain_scores_gemma":[0.9992368,0.000020388701,0.00029360031,0.00016417593,0.0002373528,0.000047636986],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036970826,0.00012931736,0.00042230758,0.00010628513,0.000040089617,0.000009547099,0.00009339627,0.00025802146,0.000004921023],"category_scores_gemma":[0.0001101728,0.000106873056,0.0002648065,0.0000796601,0.00016568179,0.0000037802165,0.000074112686,0.00013877371,9.066793e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026163924,0.000017320617,0.0006161871,0.000053269832,0.00031193704,0.000017210135,0.000012110254,0.00026379098,0.99715203,0.0003506501,0.00039496503,0.00054889824],"study_design_scores_gemma":[0.00067808636,0.00028884213,0.001986139,0.000035640933,0.00019350312,0.00020939331,0.00009137342,0.000024058778,0.9957908,0.00030298758,0.00031318815,0.00008602394],"about_ca_topic_score_codex":0.0000023169089,"about_ca_topic_score_gemma":1.7374516e-7,"teacher_disagreement_score":0.13078077,"about_ca_system_score_codex":0.000009528497,"about_ca_system_score_gemma":0.00006283319,"threshold_uncertainty_score":0.43581566},"labels":[],"label_agreement":null},{"id":"W4414957485","doi":"10.1177/14703203251386305","title":"Dose-dependent effects of the ACE inhibitor, ramipril, on kidney function and structure in the Alport COL4A3 <sup>−/−</sup> mouse","year":2025,"lang":"en","type":"article","venue":"Journal of the Renin-Angiotensin-Aldosterone System","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"St. Michael's Hospital Foundation","keywords":"Ramipril; Alport syndrome; ACE inhibitor; Glomerulosclerosis; Podocyte; Renal function; Kidney; Kidney disease","score_opus":0.004093256759083831,"score_gpt":0.20397366934408995,"score_spread":0.1998804125850061,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414957485","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99469477,0.0011677169,0.00032288945,0.0018259725,0.0013498898,0.0005776048,0.000012233078,0.000004985081,0.000043962813],"genre_scores_gemma":[0.99824494,0.00004166582,0.000105633175,0.000789397,0.000348067,0.0000037282095,0.0000031006407,0.000024119872,0.00043932008],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9977689,0.00060753344,0.0006394874,0.0002582374,0.0004880664,0.00023778027],"domain_scores_gemma":[0.9984515,0.000073117684,0.0006228135,0.0006112976,0.00016987637,0.00007143547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00079689675,0.00025881018,0.00041741782,0.00009972083,0.0001649776,0.00006385493,0.0004932326,0.0002739938,0.0000028535603],"category_scores_gemma":[0.00017652233,0.00012749009,0.0002946149,0.00022072699,0.00007783851,0.000011687717,0.00021033078,0.00041798985,6.5417925e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047964836,0.000058247937,0.0019676576,0.00013467835,0.00025485296,0.000010893139,0.00033665364,0.0017233551,0.98637694,0.00014381799,0.007792831,0.0007203944],"study_design_scores_gemma":[0.0026546523,0.0008152769,0.0070208344,0.0015038576,0.00030872138,0.00034825466,0.0006177282,0.00029042727,0.9813382,0.000111611014,0.004778746,0.00021171292],"about_ca_topic_score_codex":0.000022680504,"about_ca_topic_score_gemma":0.000012828598,"teacher_disagreement_score":0.005053177,"about_ca_system_score_codex":0.00007627798,"about_ca_system_score_gemma":0.0001428182,"threshold_uncertainty_score":0.5198895},"labels":[],"label_agreement":null},{"id":"W4414989595","doi":"10.22215/cujs.v5i3.5409","title":"Testing the Benefits of Rat Tickling on a Rodent Model of Persistent Inflammatory Pain","year":2025,"lang":"en","type":"article","venue":"Carleton undergraduate journal of science.","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo; Carleton University","funders":"","keywords":"Nociception; Biopsychosocial model; Analgesic; Pain sensation; Somatosensory system; Animal testing; Rodent; Sensation; Pain assessment","score_opus":0.023126275593455415,"score_gpt":0.24261865347301775,"score_spread":0.21949237787956233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414989595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917774,0.0008641109,0.006007382,0.00045395576,0.00033377798,0.00008118883,0.0000012162608,0.0000016160637,0.0004793539],"genre_scores_gemma":[0.99836683,0.00011320815,0.0011851856,0.00016020972,0.000055764092,0.0000010261143,3.9626204e-7,0.000006019975,0.00011136466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870324,0.00006876421,0.0004638663,0.0001579581,0.0004242093,0.00018196978],"domain_scores_gemma":[0.9986236,0.00007104534,0.00043686954,0.00020240837,0.0006044706,0.000061609964],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0023351635,0.000105210136,0.00018706848,0.00016116168,0.00015456691,0.000026883703,0.00045101438,0.000051013012,0.0000016338337],"category_scores_gemma":[0.00057673745,0.00007054122,0.00022110525,0.00030392327,0.00033478893,0.000010746812,0.00009044538,0.00012370561,1.3517453e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000027984184,0.000023184235,0.00025996967,0.000021077696,0.000026446889,4.1372977e-7,0.0000948588,0.20720145,0.7888194,0.0012895071,0.000090023124,0.002145692],"study_design_scores_gemma":[0.00035279238,0.0005788905,0.00011200489,0.0003679245,0.000056592005,0.00000959724,0.0010517773,0.050670154,0.9454911,0.0011110322,0.00010222746,0.000095937125],"about_ca_topic_score_codex":0.0000040415107,"about_ca_topic_score_gemma":0.000001409001,"teacher_disagreement_score":0.15667167,"about_ca_system_score_codex":0.000041977717,"about_ca_system_score_gemma":0.00051516556,"threshold_uncertainty_score":0.28765872},"labels":[],"label_agreement":null},{"id":"W4415128778","doi":"10.1021/acs.joc.5c01533","title":"Rapid Chemical Synthesis of Neuroprotective Hi1a","year":2025,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Artificial Intelligence in Medicine (Canada)","funders":"National Institute of Allergy and Infectious Diseases; National Cancer Institute","keywords":"Chemical synthesis; Peptide synthesis; Peptide; Recombinant DNA; Biomolecule; Amino acid; Translation (biology); Chemical modification","score_opus":0.004668184829212769,"score_gpt":0.20667571891702619,"score_spread":0.2020075340878134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415128778","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99369764,0.0012740792,0.003178423,0.00022942906,0.00010084077,0.00004844458,0.0000029307769,0.0000027646545,0.001465473],"genre_scores_gemma":[0.9989197,0.00032766254,0.000286805,0.00006685723,0.00017595713,0.0000010431246,8.977272e-7,0.000012021483,0.00020903128],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99929285,0.00004935234,0.00031724852,0.00009344018,0.0001337008,0.000113422524],"domain_scores_gemma":[0.99923307,0.000060392413,0.0002654774,0.00023504072,0.00016792133,0.000038071685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042088467,0.00010352871,0.00018867111,0.000015146922,0.000036912697,0.0000067790975,0.00037501537,0.00010926613,0.00040039947],"category_scores_gemma":[0.00044933232,0.00007219864,0.00012755631,0.00010831334,0.00006940113,0.0000022614856,0.00009808652,0.00018796006,8.9207776e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015507021,0.000035570094,0.000013576553,0.000038575996,0.00010853361,0.0000014871463,0.000023777722,0.0000054359125,0.9968282,0.0000039930155,0.0004084848,0.0023772682],"study_design_scores_gemma":[0.00023484975,0.00004628856,0.000019347437,0.00005605644,0.00007886002,0.000086585205,0.0001535807,0.0000062173644,0.99800175,0.0001571671,0.001095928,0.0000633623],"about_ca_topic_score_codex":0.0000011521682,"about_ca_topic_score_gemma":1.05940956e-7,"teacher_disagreement_score":0.0052221096,"about_ca_system_score_codex":0.000017485438,"about_ca_system_score_gemma":0.00014027343,"threshold_uncertainty_score":0.43840933},"labels":[],"label_agreement":null},{"id":"W4415211976","doi":"10.1101/2025.10.14.682450","title":"4E-BP2-dependent translational control in GABAergic interneurons is required for long-term memory","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"GABAergic; Inhibitory postsynaptic potential; Translation (biology); Excitatory postsynaptic potential; Conditional gene knockout; Neuropeptide; Synaptic plasticity; Neuroplasticity","score_opus":0.013411477370069112,"score_gpt":0.24263122179519822,"score_spread":0.2292197444251291,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415211976","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92084587,0.002204085,0.07221027,0.00034395812,0.0015989618,0.0015684563,0.0011388027,0.00007162985,0.000017951706],"genre_scores_gemma":[0.9965522,0.00024184883,0.0014309105,0.0006625713,0.0005223538,0.00041179842,0.000007674057,0.00008453248,0.00008608462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99719477,0.00013138278,0.0006657518,0.0012074639,0.000273202,0.0005274215],"domain_scores_gemma":[0.998389,0.000045283097,0.0002711701,0.00082611403,0.00030506,0.00016336112],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00048764315,0.0005290168,0.0005496114,0.00022090077,0.0000938026,0.0001151471,0.00059620576,0.00075624045,0.00009918709],"category_scores_gemma":[0.00009555758,0.0005975363,0.00035040494,0.00013679947,0.000064113425,0.000011001465,0.00024137659,0.0004248835,0.0000075645844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002305277,0.00013705484,0.0059985984,0.00033731575,0.00021367398,0.000017657849,0.0000092335895,0.00028028127,0.9923654,0.00019358173,0.00020771436,0.00000894464],"study_design_scores_gemma":[0.0024081485,0.00012369583,0.010045827,0.00038497758,0.00012438442,2.6845422e-8,0.0000022578802,0.00084145967,0.9845385,0.000008843222,0.0008089713,0.00071289856],"about_ca_topic_score_codex":0.000017140937,"about_ca_topic_score_gemma":0.000019995467,"teacher_disagreement_score":0.07570634,"about_ca_system_score_codex":0.00007033369,"about_ca_system_score_gemma":0.00063076586,"threshold_uncertainty_score":0.9996476},"labels":[],"label_agreement":null},{"id":"W4415371423","doi":"10.1016/j.ejmcr.2025.100302","title":"The impact of secondary site interactions on the binding specificity of bitopic dopamine D2/D3 receptor ligands","year":2025,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry Reports","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Nemzeti Kutatási, Fejlesztési és Innovaciós Alap; Általános Orvostudományi Kar, Pécsi Tudományegyetem; Nemzeti Kutatási Fejlesztési és Innovációs Hivatal; Nemzeti Kutatási és Technológiai Hivatal; Magyar Tudományos Akadémia; Hungarian Scientific Research Fund; Deutsche Forschungsgemeinschaft; Canadian Institutes of Health Research; Hungarian Research Network","keywords":"G protein-coupled receptor; Receptor; Dopamine receptor D2; Dopamine receptor; Dopaminergic; Dopamine receptor D3; Dopamine; Functional selectivity; Binding site","score_opus":0.01051303338622405,"score_gpt":0.2633189411748376,"score_spread":0.25280590778861356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415371423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887702,0.0007872541,0.00023440146,0.00026602283,0.0004888491,0.000052885644,0.0000061548812,0.0000021285023,0.009392112],"genre_scores_gemma":[0.99756944,0.00018927839,0.00005852591,0.000021751182,0.00056409114,5.48851e-7,0.000011281287,0.000012906585,0.0015721612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99853605,0.00009950738,0.000827307,0.00014953109,0.00024718078,0.00014044896],"domain_scores_gemma":[0.9981663,0.000098795994,0.0010563432,0.0003437126,0.00026342596,0.00007137871],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015595163,0.00014159153,0.00023723426,0.000038762977,0.00011926385,0.000017914583,0.00023444521,0.00003694772,0.00024154977],"category_scores_gemma":[0.00054379174,0.0000757133,0.0002879787,0.00012453293,0.00012104464,0.00000509215,0.000070697315,0.00037322677,8.173325e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016007022,0.000053123964,0.0011316239,0.000028035778,0.00017362197,0.00006855118,0.000061171646,0.000043177442,0.99010974,0.000005594957,0.0052772933,0.002888005],"study_design_scores_gemma":[0.00022709172,0.00040797328,0.00088894495,0.0003348683,0.000036315458,0.00035800037,0.00040644302,0.0000060803186,0.98593664,0.000022300039,0.011311464,0.000063859494],"about_ca_topic_score_codex":0.0000034293125,"about_ca_topic_score_gemma":3.9674995e-7,"teacher_disagreement_score":0.008799263,"about_ca_system_score_codex":0.000030501627,"about_ca_system_score_gemma":0.00018112897,"threshold_uncertainty_score":0.30874988},"labels":[],"label_agreement":null},{"id":"W4415382370","doi":"10.17504/protocols.io.x54v95onzl3e/v1","title":"Live-Imaging of GCase Activity in iPSC-Derived Dopaminergic Neurons Using the Lyso-FQ Probe v1","year":2025,"lang":"","type":"preprint","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"Michael J. Fox Foundation for Parkinson's Research","keywords":"Dopaminergic; Premovement neuronal activity; Glucocerebrosidase; Midbrain; Neuron","score_opus":0.021923006170344844,"score_gpt":0.2757355028020804,"score_spread":0.25381249663173555,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415382370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9365592,0.0016809237,0.057416085,0.0003270964,0.00097696,0.0012649867,0.0000784397,0.000016356391,0.0016799495],"genre_scores_gemma":[0.99364495,0.0013280798,0.003475509,0.00022502909,0.00024939489,0.000068836096,0.00005938375,0.00005484768,0.00089393836],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9955868,0.0007258823,0.0010287289,0.0015367551,0.00035857412,0.0007632368],"domain_scores_gemma":[0.9972752,0.0001140372,0.0007291388,0.0014353332,0.00030238635,0.00014390414],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0009072766,0.00082810724,0.00093023566,0.00023369973,0.00026150775,0.00012501121,0.0009692214,0.00060761295,0.00036566844],"category_scores_gemma":[0.00018595297,0.00067934755,0.0006302374,0.00034073906,0.0002866362,0.000012995489,0.0023963365,0.0010055626,0.0000027490694],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020256997,0.00032959486,0.0008173904,0.00039068545,0.00015785609,0.000028098179,0.00034402235,0.012748783,0.9793748,0.00016296563,0.00002004894,0.0054231305],"study_design_scores_gemma":[0.0008277064,0.00013756035,0.00032867127,0.00051095715,0.00019045499,0.000032024138,0.00092762616,0.06478035,0.930913,0.00022395057,0.00042964274,0.0006980576],"about_ca_topic_score_codex":0.0016776106,"about_ca_topic_score_gemma":0.0002509907,"teacher_disagreement_score":0.05708578,"about_ca_system_score_codex":0.000096241885,"about_ca_system_score_gemma":0.00090052636,"threshold_uncertainty_score":0.9995658},"labels":[],"label_agreement":null},{"id":"W4415521265","doi":"10.1016/j.cell.2025.10.002","title":"Unveiling conformation-selective regulation of the norepinephrine transporter","year":2025,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Shanghai Lingjun Program; China Postdoctoral Science Foundation; National Natural Science Foundation of China; National Key Research and Development Program of China; Canadian Anesthesiologists' Society; China Association for Science and Technology","keywords":"Allosteric regulation; Norepinephrine transporter; Transporter; Neurotransmission; Virtual screening; Antidepressant; Norepinephrine","score_opus":0.0035001247971334216,"score_gpt":0.20008124641369268,"score_spread":0.19658112161655927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415521265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96657616,0.00018792921,0.019910943,0.000045024743,0.00014756582,0.00011709812,0.0000032796045,0.0000035323046,0.013008472],"genre_scores_gemma":[0.9976446,0.000016829226,0.00024230167,0.00009715737,0.00002593094,0.0000032937805,0.000026289023,0.0000029643668,0.0019406087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99970204,0.000011531307,0.00011808189,0.000073053794,0.000040996074,0.000054273496],"domain_scores_gemma":[0.9997639,0.0000033544707,0.000048703532,0.000118074706,0.000058003054,0.000007956757],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000060329294,0.000042652515,0.000048681213,0.0000142526715,0.00003564672,0.0000025256923,0.00006538037,0.000046738245,0.000055527486],"category_scores_gemma":[0.000006161382,0.00003151741,0.000050261388,0.00006636692,0.00001534881,0.0000016364717,0.000012088457,0.000028737137,0.0000013024837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012832602,0.000008419385,0.00030245262,0.000017563254,0.000008245015,1.4883981e-8,0.00005124863,0.00043019172,0.99820995,0.00019619778,0.00037863772,0.00038426684],"study_design_scores_gemma":[0.00018796783,0.00001904865,0.0036126066,0.000010687465,0.00000814996,1.9680017e-7,0.00003600611,0.00034044075,0.98952323,0.0001925287,0.006035943,0.000033214445],"about_ca_topic_score_codex":0.000004881133,"about_ca_topic_score_gemma":0.000004126203,"teacher_disagreement_score":0.031068468,"about_ca_system_score_codex":0.0000039320207,"about_ca_system_score_gemma":0.00003314413,"threshold_uncertainty_score":0.12852427},"labels":[],"label_agreement":null},{"id":"W4415617777","doi":"10.1002/cmdc.202500572","title":"Synthesis and Evaluation of Fluorinated Peptidomimetics Enabling the Development of <sup>18</sup> F‐Labeled Radioligands Targeting Muscarinic Acetylcholine Receptor Subtype M3","year":2025,"lang":"en","type":"article","venue":"ChemMedChem","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Northern Alberta Institute of Technology; Alberta Cancer Foundation; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Allard Foundation; Alberta Cancer Foundation","keywords":"Radioligand; Peptidomimetic; Pharmacophore; Muscarinic acetylcholine receptor; Reductive amination; Receptor; Radioligand Assay; Acetylcholine","score_opus":0.023818409375828346,"score_gpt":0.27816766836542456,"score_spread":0.2543492589895962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415617777","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99589175,0.002277895,0.00085692207,0.00006850386,0.000094594296,0.00030175224,0.0000054789134,0.000009526759,0.00049356854],"genre_scores_gemma":[0.9933274,0.0002600677,0.005989633,0.00002541539,0.00009305369,0.000054509474,0.00006922827,0.000020836356,0.00015985925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99848837,0.00011026385,0.0005558918,0.00033342515,0.00028102592,0.00023105029],"domain_scores_gemma":[0.99884,0.0001104299,0.00023693411,0.00030011896,0.00046258152,0.000049933784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020908592,0.00019246057,0.00030345595,0.00007469906,0.000120562,0.0000152738,0.00022890377,0.00019786994,0.00013121324],"category_scores_gemma":[0.0009826475,0.00015490751,0.00008851123,0.00024783172,0.000090293,0.0000056063045,0.00016198505,0.000117917836,0.0000011324117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007493278,0.000046551435,0.00023295589,0.000102435704,0.00017607899,5.4186227e-8,0.00047577813,0.00019095361,0.9837213,0.000032113472,0.0003074196,0.014639421],"study_design_scores_gemma":[0.0007871868,0.000034344514,0.00008515857,0.00010989055,0.00013299215,7.8341213e-7,0.00086528703,0.0033336137,0.99285245,0.000043445463,0.0016075321,0.0001473381],"about_ca_topic_score_codex":0.0000048434044,"about_ca_topic_score_gemma":0.0000018247364,"teacher_disagreement_score":0.014492083,"about_ca_system_score_codex":0.00004049253,"about_ca_system_score_gemma":0.00029150376,"threshold_uncertainty_score":0.6316945},"labels":[],"label_agreement":null},{"id":"W4415901194","doi":"10.1016/j.isci.2025.113935","title":"Molecular insights into ligand recognition and receptor activation of GPR15","year":2025,"lang":"en","type":"article","venue":"iScience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Singapore National Academy of Science; National Key Research and Development Program of China Stem Cell and Translational Research; Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Canadian Anesthesiologists' Society; National Key Research and Development Program of China; Chinese Academy of Sciences, Shanghai Branch; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Receptor; Mutagenesis; Docking (animal); Molecular recognition; Immune system; Protein–protein interaction; Ligand (biochemistry); Plasma protein binding","score_opus":0.010648594332472323,"score_gpt":0.24218593745439415,"score_spread":0.23153734312192184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415901194","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9749911,0.0005463013,0.023615852,0.000070555805,0.000085788735,0.000068285895,9.1106733e-7,0.0000035750184,0.0006176238],"genre_scores_gemma":[0.99792045,0.00013576345,0.0016945793,0.00013235348,0.000016672455,0.000005322328,0.0000136202025,0.0000027286032,0.00007853265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995646,0.000018378403,0.00009493701,0.00018534281,0.00006998134,0.0000667841],"domain_scores_gemma":[0.9997681,0.0000063572616,0.000041245887,0.000094619616,0.000067165616,0.000022504166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000954623,0.000052341427,0.000057370187,0.000045169512,0.000052738844,0.000014058698,0.00007108736,0.00005667011,0.000006869959],"category_scores_gemma":[0.00007243222,0.000047477362,0.000018546438,0.00013258783,0.000062011764,0.000006636892,0.000048001737,0.000026876498,0.000001457305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000107778715,0.000010035188,0.00004857034,0.000011324846,0.0000040498126,7.202841e-8,0.00008852394,0.000012658933,0.9804161,0.0002484376,0.0000531355,0.019096294],"study_design_scores_gemma":[0.000110633584,0.00007735561,0.00009891946,0.000038375816,0.0000031770169,2.4379014e-7,0.00007670016,0.0000789499,0.99446,0.002744572,0.002256234,0.000054870317],"about_ca_topic_score_codex":0.000015675489,"about_ca_topic_score_gemma":0.0000023557134,"teacher_disagreement_score":0.02292932,"about_ca_system_score_codex":0.0000049915184,"about_ca_system_score_gemma":0.000037839054,"threshold_uncertainty_score":0.19360706},"labels":[],"label_agreement":null},{"id":"W4416144644","doi":"10.1021/acschemneuro.5c00521","title":"G Protein: β-Arrestin Bias Confers Differential Regulation of Gα <sub>q</sub> Signaling by GPR17 Antagonists","year":2025,"lang":"en","type":"article","venue":"ACS Chemical Neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Multiple Sclerosis Australia","keywords":"Signal transduction; G protein-coupled receptor; HEK 293 cells; Receptor; Endogeny; G protein; Cell signaling; Functional selectivity","score_opus":0.012531765809044778,"score_gpt":0.2361758411343569,"score_spread":0.22364407532531214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416144644","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944705,0.000041826443,0.004957856,0.00009017124,0.00016491121,0.00019711272,0.0000089585465,0.0000104045685,0.00005829664],"genre_scores_gemma":[0.9995702,0.000016352224,0.00014764915,0.00013152513,0.000033397184,0.000015936757,0.000029477773,0.000009421139,0.00004606253],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987684,0.000046681445,0.0002896262,0.00045349944,0.00019457661,0.00024721737],"domain_scores_gemma":[0.9995578,0.000019828582,0.00010380404,0.00020926067,0.000051844294,0.000057440284],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001430438,0.00013822239,0.00015956345,0.000048181457,0.00005492236,0.000033216984,0.00027055817,0.00012614056,0.0000054505695],"category_scores_gemma":[0.000290256,0.00013460728,0.000057320533,0.000230807,0.00017133649,0.000007915726,0.00012308772,0.00010986898,6.035429e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047698115,0.00005669997,0.00024153075,0.000022867998,0.0000017384017,8.5654455e-7,0.000006694388,0.00004612247,0.99848545,0.00020914864,0.00012138034,0.0007597996],"study_design_scores_gemma":[0.00032116665,0.00006149251,0.00027224683,0.00005316722,0.000004594364,0.0000014666346,0.0000065018203,0.0006051954,0.9981125,0.0002074797,0.0002311805,0.0001230226],"about_ca_topic_score_codex":0.000006910312,"about_ca_topic_score_gemma":7.025823e-7,"teacher_disagreement_score":0.0050997157,"about_ca_system_score_codex":0.0000124947055,"about_ca_system_score_gemma":0.00007043463,"threshold_uncertainty_score":0.5489126},"labels":[],"label_agreement":null},{"id":"W4416179079","doi":"10.1073/pnas.2512423122","title":"Dissociation kinetics of G proteins from G protein–coupled receptors and effects of allosteric modulation","year":2025,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"Office of Advanced Cyberinfrastructure; National Health and Medical Research Council; Australian Research Council; Office of Science; National Institute of General Medical Sciences; Medical Research Council; U.S. Department of Energy; Department of Health and Aged Care, Australian Government; National Heart Foundation of Australia; National Science Foundation; Department of Education and Training; National Institutes of Health","keywords":"Allosteric regulation; G protein-coupled receptor; Dissociation (chemistry); Förster resonance energy transfer; Kinetics; G protein; Protein–protein interaction","score_opus":0.010586157967173911,"score_gpt":0.2573617796402425,"score_spread":0.24677562167306857,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416179079","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9989794,0.00018927404,0.00010807693,0.00021851747,0.00001894252,0.0003183377,0.0000059144145,0.000001480936,0.00016004371],"genre_scores_gemma":[0.9968958,0.00002897725,0.0029488595,0.000022593418,0.000024641868,0.00001197393,9.4263976e-7,0.0000022067813,0.00006402592],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992091,0.0000078492685,0.00024102186,0.00014454627,0.00033937467,0.000058092548],"domain_scores_gemma":[0.9993281,0.000027376585,0.0004131306,0.000007794505,0.00021292355,0.000010687925],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031347515,0.00005810469,0.00011578494,0.00006150206,0.00003797842,0.000005614489,0.00019602949,0.00008990303,0.0000024273552],"category_scores_gemma":[0.0004232845,0.000042859803,0.000041393956,0.00024047786,0.0001899494,0.000014096395,0.000082868246,0.00003835329,2.4543265e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001849301,0.000028936534,0.0017636165,0.000121736426,0.00001915069,2.732243e-10,0.000055994915,0.00004343092,0.994565,0.002893323,0.000012915609,0.00047736824],"study_design_scores_gemma":[0.00015572106,0.00011082901,0.021681434,0.00016292877,0.000011150992,7.255645e-8,0.000038937345,0.0009102683,0.96420693,0.0126677,0.000017470025,0.000036577767],"about_ca_topic_score_codex":0.000010171991,"about_ca_topic_score_gemma":9.513818e-8,"teacher_disagreement_score":0.030358123,"about_ca_system_score_codex":0.000007744002,"about_ca_system_score_gemma":0.000015339354,"threshold_uncertainty_score":0.17477721},"labels":[],"label_agreement":null},{"id":"W4416203511","doi":"10.7554/elife.104549.3","title":"Membrane-mimetic thermal proteome profiling (MM-TPP) toward mapping membrane protein–ligand dynamic interactions","year":2025,"lang":"en","type":"article","venue":"eLife","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Regina; University of British Columbia","funders":"","keywords":"Proteome; Druggability; Membrane protein; Interactome; Membrane; Human proteome project; Proteomics","score_opus":0.011078508951985106,"score_gpt":0.2593634743344034,"score_spread":0.24828496538241826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416203511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97970176,0.00042384284,0.01548391,0.0004738797,0.00045673174,0.0009971847,0.000011682354,0.000059965765,0.0023910576],"genre_scores_gemma":[0.9893645,0.000048012465,0.0059231287,0.00029915827,0.00020673373,0.000257954,0.00008302664,0.00003498075,0.003782502],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985062,0.0000822755,0.00036102918,0.00048791987,0.00019832216,0.0003642626],"domain_scores_gemma":[0.99930865,0.000013472326,0.000111131616,0.00035618624,0.00012504258,0.00008552969],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031102626,0.00024536767,0.00024074173,0.00012335868,0.00019404195,0.00007659007,0.00026047078,0.00016184656,0.00011497232],"category_scores_gemma":[0.00011337616,0.00022857079,0.00015728781,0.0002059886,0.000046167886,0.000011712439,0.00014879825,0.00023699828,0.000030770872],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000063186984,0.00004777712,0.000058441332,0.00012606898,0.000107029286,0.000003995056,0.000085240164,0.00020336494,0.9976922,0.00017163037,0.000038355814,0.0014026633],"study_design_scores_gemma":[0.00046504036,0.0000824104,0.0000988125,0.00015319906,0.000024398241,0.0000078215735,0.00023930658,0.0014289053,0.9899023,0.00004287327,0.0073070046,0.00024788408],"about_ca_topic_score_codex":0.000021832004,"about_ca_topic_score_gemma":0.00000992777,"teacher_disagreement_score":0.009662759,"about_ca_system_score_codex":0.00003557384,"about_ca_system_score_gemma":0.00014875003,"threshold_uncertainty_score":0.9320846},"labels":[],"label_agreement":null},{"id":"W4416967325","doi":"10.1001/jamapsychiatry.2025.3636","title":"Muscarinic Receptor Activators—What Is Their Place in Clinical Care?","year":2025,"lang":"en","type":"article","venue":"JAMA Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Muscarinic acetylcholine receptor; Muscarinic acetylcholine receptor M4; Muscarinic acetylcholine receptor M1; Muscarinic acetylcholine receptor M3; Muscarinic acetylcholine receptor M2; Receptor; Muscarinic acetylcholine receptor M5","score_opus":0.008242864126542139,"score_gpt":0.2908631171929872,"score_spread":0.28262025306644506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416967325","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9830828,0.0071037905,0.00033395452,0.0020582562,0.004848416,0.00021698073,0.000014215554,0.000020019228,0.0023215914],"genre_scores_gemma":[0.9885406,0.00227757,0.0019970508,0.0051097884,0.00093265646,0.00003129258,0.00007643922,0.00003132492,0.0010032721],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984673,0.00014205203,0.00044729924,0.00055757456,0.00010123215,0.00028451197],"domain_scores_gemma":[0.99922395,0.000031427106,0.00010090566,0.0005074586,0.00005739284,0.00007884447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037810186,0.00020333848,0.00024401101,0.00007765735,0.00007162779,0.000095462296,0.00031420644,0.0004911065,0.00019358748],"category_scores_gemma":[0.000046645164,0.00018405811,0.00024168084,0.00018851191,0.00004274418,0.000014838583,0.00013899796,0.00032679614,0.00002555288],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020188806,0.00094449514,0.19316153,0.00035567503,0.0005872331,0.0000034384054,0.0015778934,0.00006339129,0.25411585,0.0049419776,0.15211858,0.39011106],"study_design_scores_gemma":[0.0053706383,0.00060641207,0.011184296,0.000567987,0.00004100924,0.0000040636946,0.01156939,0.000070207876,0.25725058,0.0021189002,0.71040493,0.0008115601],"about_ca_topic_score_codex":0.000019636691,"about_ca_topic_score_gemma":0.00005626755,"teacher_disagreement_score":0.55828637,"about_ca_system_score_codex":0.000026136597,"about_ca_system_score_gemma":0.00028505837,"threshold_uncertainty_score":0.7505672},"labels":[],"label_agreement":null},{"id":"W45715142","doi":"10.1016/b978-0-12-408143-7.00001-3","title":"Spatial Intensity Distribution Analysis (SpIDA)","year":2013,"lang":"en","type":"article","venue":"Methods in cell biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; McGill University; University of British Columbia; Institut Universitaire en Santé Mentale de Québec","funders":"Canadian Institutes of Health Research","keywords":"Biology; Confocal microscopy; Biological system; Biophysics; Colocalization; Confocal; Receptor; Receptor tyrosine kinase; Immunostaining; Cell biology; Biochemistry; Optics; Immunohistochemistry","score_opus":0.01728354411179402,"score_gpt":0.32848784511053347,"score_spread":0.31120430099873947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W45715142","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42733243,0.0001482183,0.5717903,0.000034187902,0.0001954078,0.00008785556,0.000008136204,0.0000061216438,0.00039738615],"genre_scores_gemma":[0.8911848,0.000062377774,0.10780206,0.00017883572,0.00012245348,0.000029236478,0.00045591456,0.0000080046275,0.00015630732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99863887,0.00042996628,0.0002488063,0.0003765159,0.00003704172,0.00026880918],"domain_scores_gemma":[0.9994698,0.000038525843,0.00008233516,0.00026677758,0.00008401301,0.000058515343],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007254226,0.00012984374,0.00026724624,0.000074695134,0.000043529977,0.000013405755,0.00015408309,0.00039563637,0.0005425353],"category_scores_gemma":[0.00014068141,0.00011337819,0.0001491148,0.00022963283,0.00006121629,0.0000021573576,0.000117095275,0.0001678273,0.000020905443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016758346,0.000028918577,0.012241513,0.00000310889,0.00005200595,4.2475634e-7,0.000011957049,0.00007013848,0.95855504,0.0000424197,0.00012231857,0.028855419],"study_design_scores_gemma":[0.00020493117,0.00017194812,0.00691941,0.0000013667351,0.000049324764,9.911953e-7,0.000043477598,0.0032468224,0.97901034,0.0009432739,0.009237169,0.0001709679],"about_ca_topic_score_codex":0.00056411105,"about_ca_topic_score_gemma":0.00006264164,"teacher_disagreement_score":0.46398818,"about_ca_system_score_codex":0.000017929613,"about_ca_system_score_gemma":0.000017264825,"threshold_uncertainty_score":0.59403807},"labels":[],"label_agreement":null},{"id":"W51235113","doi":"10.1096/fasebj.21.6.lb82","title":"The Dynamic regulation of ßarrestin trafficking in endosomes","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"William Osler Health System; McGill University","funders":"","keywords":"Endosome; Arrestin; Internalization; G protein-coupled receptor; Receptor; Cell biology; Chemistry; Agonist; Avidity; Biology; Biochemistry; Immunology; Antibody","score_opus":0.007981745930483614,"score_gpt":0.24398206243483078,"score_spread":0.23600031650434716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W51235113","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99012023,0.0010798794,0.008281496,0.00010006294,0.00018863892,0.00004993631,5.779592e-7,0.0000016510596,0.00017753338],"genre_scores_gemma":[0.99927944,0.00016006186,0.00028322169,0.000025925941,0.00013082767,5.853522e-7,0.0000021469334,0.0000066377725,0.00011112456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994057,0.000060136656,0.00021152702,0.00006135474,0.00011102406,0.00015025036],"domain_scores_gemma":[0.9996627,0.000046058827,0.00012325849,0.00010875615,0.00003443697,0.000024814286],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012537384,0.00005409715,0.00005622535,0.000026431975,0.00014439308,0.000020488265,0.00015589269,0.000041784588,0.000015260151],"category_scores_gemma":[0.00006154654,0.000030167357,0.00005412854,0.000059079208,0.000041212268,0.0000022452366,0.000020546133,0.00011795976,7.2865436e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005328234,0.0000073461974,0.00036287104,0.000001205874,0.000009402045,0.0000015431775,0.00009923787,0.0010258419,0.982759,0.00015760903,0.000019693554,0.015502988],"study_design_scores_gemma":[0.00027237114,0.00007204689,0.006292789,0.000021820853,0.000005708597,0.000073169875,0.0005050652,0.00079737604,0.99066967,0.00065618183,0.000582682,0.00005114375],"about_ca_topic_score_codex":0.000003873713,"about_ca_topic_score_gemma":0.000059665188,"teacher_disagreement_score":0.015451844,"about_ca_system_score_codex":0.000012032602,"about_ca_system_score_gemma":0.00002970857,"threshold_uncertainty_score":0.12301891},"labels":[],"label_agreement":null},{"id":"W51659193","doi":"10.1007/978-1-4939-0956-8_9","title":"Pharmacogenetics of the G Protein-Coupled Receptors","year":2014,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; Canada Research Chairs; University of Toronto; Lunenfeld-Tanenbaum Research Institute; University of New Brunswick","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Pharmacogenomics; Pharmacogenetics; Biology; Receptor; Computational biology; Cannabinoid; Cannabinoid receptor; Drug; Pharmacology; Genetics; Bioinformatics; Gene; Agonist; Genotype","score_opus":0.03366837627831454,"score_gpt":0.420562522465909,"score_spread":0.38689414618759443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W51659193","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000100732694,0.6970486,0.30120665,0.000006941133,0.0006582345,0.0008389495,0.000010910459,0.0000055635264,0.00012339646],"genre_scores_gemma":[0.000013103659,0.75593245,0.24322064,0.000074211486,0.00015875492,0.00020601809,0.00008181459,0.00008655571,0.00022641623],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99426824,0.0035168228,0.0009553575,0.00071732805,0.000118303215,0.0004239795],"domain_scores_gemma":[0.99819714,0.000077645935,0.00065991224,0.0009169529,0.000080914644,0.000067415574],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0019020691,0.00050178415,0.001462341,0.00014627221,0.00004619166,0.000009541582,0.0010059421,0.0009831882,0.00008880673],"category_scores_gemma":[0.0005445493,0.000343723,0.00086485734,0.0003644431,0.00020486476,7.7001476e-7,0.00049043074,0.0004424879,0.000003853619],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000072120033,0.000028987315,0.0000048533093,0.0012393238,0.00013612064,0.0000010254591,0.0000055471423,0.000010445903,0.5692546,0.0004208981,0.000019567091,0.42887145],"study_design_scores_gemma":[0.00018471519,0.00013679946,1.436981e-7,0.0007768185,0.00015381286,0.00001070215,0.000002804932,0.000020029842,0.25269756,0.0004523726,0.74525285,0.0003113757],"about_ca_topic_score_codex":0.0000116950405,"about_ca_topic_score_gemma":0.000002769951,"teacher_disagreement_score":0.7452333,"about_ca_system_score_codex":0.000029230987,"about_ca_system_score_gemma":0.00023365722,"threshold_uncertainty_score":0.9999015},"labels":[],"label_agreement":null},{"id":"W52812077","doi":"10.1007/978-1-59745-205-2_8","title":"G Protein-Coupled Receptor Pharmacogenetics","year":2008,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Pharmacogenomics; G protein-coupled receptor; Pharmacogenetics; Receptor; Biology; Computational biology; Gene; 5-HT5A receptor; Single-nucleotide polymorphism; Genetics; Pharmacology; Genotype","score_opus":0.04669006543727119,"score_gpt":0.42818064027582264,"score_spread":0.3814905748385515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W52812077","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000040587216,0.66750723,0.33083493,0.000005516416,0.00046323272,0.0009351328,0.00002738349,0.000018696239,0.00016730161],"genre_scores_gemma":[5.8168604e-7,0.61163497,0.38689467,0.00007523536,0.00023885691,0.0003645443,0.0004145262,0.00011270367,0.0002639017],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9941321,0.0026636359,0.0010497017,0.0012727269,0.00013578376,0.0007460392],"domain_scores_gemma":[0.9983696,0.00007016589,0.00045660703,0.00084985216,0.00009082546,0.00016299821],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009742137,0.0008159548,0.0018137543,0.00031339622,0.00008203726,0.00002092821,0.0008233375,0.0015393507,0.00022520336],"category_scores_gemma":[0.00038921135,0.0007287845,0.00086849794,0.00041462522,0.0001805986,0.0000017449925,0.00041697553,0.0006403577,0.000042166543],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011684182,0.000045441557,7.8583446e-7,0.00051881076,0.00015552207,0.000021544642,0.000006129826,0.0000041048233,0.5276525,0.00015271129,0.000072341216,0.47135845],"study_design_scores_gemma":[0.00031779893,0.00024341502,2.9481875e-8,0.00056741526,0.000089627814,0.000089549736,0.0000035193834,0.000018594192,0.13772105,0.00018659321,0.86007607,0.0006863395],"about_ca_topic_score_codex":0.000012333546,"about_ca_topic_score_gemma":0.0000016506359,"teacher_disagreement_score":0.8600037,"about_ca_system_score_codex":0.00006582632,"about_ca_system_score_gemma":0.00039393248,"threshold_uncertainty_score":0.9997569},"labels":[],"label_agreement":null},{"id":"W56134520","doi":"10.1016/b978-0-12-381298-8.00016-2","title":"Probing the Constitutive Activity Among Dopamine D1 and D5 Receptors and Their Mutants","year":2010,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Receptor; Dopamine receptor; G protein-coupled receptor; Biology; Cell biology; Intracellular; HEK 293 cells; Biochemistry","score_opus":0.025243114816886663,"score_gpt":0.35314051262589646,"score_spread":0.3278973978090098,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W56134520","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9331723,0.0007151894,0.062110424,0.00027265187,0.00201772,0.00070675125,0.000014387607,0.000032358825,0.00095824164],"genre_scores_gemma":[0.64086425,0.00020969972,0.3580679,0.0003428171,0.00018019447,0.0001476928,0.000009778518,0.000048099064,0.00012955986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99069434,0.006246242,0.00069293263,0.0013577468,0.00011436639,0.00089437654],"domain_scores_gemma":[0.9961386,0.002478217,0.0003396613,0.0007826663,0.000088673856,0.00017219501],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.008732082,0.000621158,0.00096923276,0.00036594248,0.00031787774,0.000053954544,0.0005246098,0.0012733481,0.00012456671],"category_scores_gemma":[0.0031110675,0.00046838302,0.00012575164,0.0003897437,0.0024617375,0.000023644121,0.0005497832,0.0017448815,0.0000020795042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002525386,0.00013329722,0.0068466426,0.000020091324,0.00007082388,0.000029488849,0.0006873765,0.0000349137,0.88109404,0.0029666028,0.00002539886,0.10783877],"study_design_scores_gemma":[0.0018847575,0.0012605767,0.041429866,0.000058231457,0.00004017208,0.0006451378,0.00075549196,0.00032822604,0.9306376,0.015529207,0.0066212155,0.0008095478],"about_ca_topic_score_codex":0.00023143673,"about_ca_topic_score_gemma":0.0015123307,"teacher_disagreement_score":0.29595748,"about_ca_system_score_codex":0.000046438792,"about_ca_system_score_gemma":0.00013961815,"threshold_uncertainty_score":0.9997768},"labels":[],"label_agreement":null},{"id":"W568987353","doi":"10.1007/978-1-59259-919-6","title":"The G Protein-Coupled Receptors Handbook","year":2005,"lang":"en","type":"book","venue":"Contemporary clinical neuroscience","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biocenter, University of Oulu; Universitat Autònoma de Barcelona; Oulun Yliopisto; University of California, Irvine; University of Toronto; University of Washington; University of Glasgow; Brigham and Women's Hospital","keywords":"Receptor; G protein-coupled receptor; Computational biology; Neuroscience; Chemistry; Biology; Biochemistry","score_opus":0.05440044263652703,"score_gpt":0.31614286922421414,"score_spread":0.2617424265876871,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W568987353","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.021930808,0.08814836,0.017085427,0.0059906286,0.04326473,0.0131289195,0.00023057025,0.00060674996,0.8096138],"genre_scores_gemma":[0.012149677,0.0022645546,0.00022816545,0.0024895922,0.0026072366,0.0000731991,0.00007303156,0.00009162323,0.9800229],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.996449,0.00025966807,0.0010980696,0.0012397164,0.0004878938,0.00046565518],"domain_scores_gemma":[0.99773586,0.00016464567,0.00060729514,0.0010493605,0.00014596983,0.0002968426],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0016457489,0.00043994279,0.00046928547,0.00003860278,0.000520626,0.00019115114,0.0013850053,0.0006338715,0.0000617408],"category_scores_gemma":[0.0010666762,0.00031116864,0.0005074418,0.000079167345,0.0009369632,0.0000115413395,0.0004589471,0.000746915,0.00007683417],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004732039,0.0001881454,0.000099813784,0.00004233675,0.00005875777,0.00004707727,0.000018753166,0.000016260214,0.3668769,0.0013519867,0.60404867,0.02677809],"study_design_scores_gemma":[0.00038899205,0.0007731957,0.000012479852,0.00010533847,0.000009796252,0.000006358809,0.0000037464124,0.00013880777,0.0091704065,0.0004417147,0.98855704,0.0003921306],"about_ca_topic_score_codex":0.0000021952922,"about_ca_topic_score_gemma":0.000006194432,"teacher_disagreement_score":0.38450834,"about_ca_system_score_codex":0.000024861292,"about_ca_system_score_gemma":0.0015526183,"threshold_uncertainty_score":0.999934},"labels":[],"label_agreement":null},{"id":"W57568958","doi":"10.1096/fasebj.24.1_supplement.850.5","title":"Arachidonoyl substrate specificity of diacylglycerol kinases","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Health Sciences Centre; McMaster University Medical Centre","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Diacylglycerol kinase; Moiety; Biochemistry; Arachidonic acid; Enzyme; Gene isoform; Kinase; Substrate (aquarium); Mutant; Chemistry; Isozyme; Cell biology; Protein kinase C; Biology; Stereochemistry; Gene","score_opus":0.011573949281442043,"score_gpt":0.23142488325586164,"score_spread":0.2198509339744196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W57568958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99699306,0.00017756144,0.0013715527,0.00007522384,0.0005418562,0.000052543448,0.000008826538,0.0000031420043,0.00077625184],"genre_scores_gemma":[0.9983541,0.00011523258,0.00047473997,0.000057730227,0.0008095938,0.0000012948785,0.0000064702626,0.000011345813,0.00016950943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999342,0.000055013934,0.00020294044,0.00010581065,0.00012940494,0.00016482515],"domain_scores_gemma":[0.99945223,0.000015697156,0.00015714884,0.00022276287,0.00007797502,0.000074184725],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00043500846,0.00009419545,0.00010460353,0.000022326896,0.0001423648,0.00003740052,0.00026362637,0.00007419736,0.00040986502],"category_scores_gemma":[0.00004702982,0.000060394625,0.00012664183,0.00004009643,0.00007860496,0.0000036020283,0.000037538357,0.00029300503,0.000007778045],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006318469,0.000029291392,0.0011474747,0.0000022670486,0.000025881029,0.0000033688393,0.000033059794,0.000060303402,0.9966555,0.0002987707,0.00020312598,0.0014777783],"study_design_scores_gemma":[0.00021951969,0.00012918738,0.0013361477,0.0000054565653,0.000013841742,0.00013413285,0.00009363067,0.000033909182,0.99609363,0.00054775923,0.0013150364,0.00007773118],"about_ca_topic_score_codex":0.000008769322,"about_ca_topic_score_gemma":0.000018647777,"teacher_disagreement_score":0.0014000472,"about_ca_system_score_codex":0.0000026816697,"about_ca_system_score_gemma":0.000048855476,"threshold_uncertainty_score":0.44877347},"labels":[],"label_agreement":null},{"id":"W57937358","doi":"10.1139/y10-013","title":"Functional linkage as a direction for studies in oxidative stress: α-adrenergic receptorsThis review is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.","year":2010,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Receptor; Adenylyl cyclase; Biology; Vascular smooth muscle; Endocrinology; Adrenergic receptor; Internal medicine; Cell biology; Oxidative stress; Diacylglycerol kinase; Signal transduction; Chemistry; Biochemistry; Protein kinase C; Medicine","score_opus":0.0348760194105396,"score_gpt":0.33927605379676923,"score_spread":0.30440003438622965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W57937358","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.03359101,0.96422714,0.0000022892268,0.00029833146,0.00094017823,0.00069510494,0.00021899711,6.9668505e-7,0.000026277477],"genre_scores_gemma":[0.0064372197,0.9917345,0.00004777733,0.00038120657,0.0011032596,0.00006583473,0.0001643046,0.00001584951,0.000050034738],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979031,0.0006088982,0.00083844835,0.00033730967,0.00006680543,0.0002454248],"domain_scores_gemma":[0.9984042,0.00015160997,0.0009255911,0.0000681144,0.0001930212,0.00025743412],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00058657915,0.00023875695,0.0013316144,0.0004894962,0.0000505051,0.000003890942,0.00010720593,0.00031820536,0.0015027758],"category_scores_gemma":[0.00032055058,0.00021113807,0.00015023343,0.00024276356,0.0002032857,0.0000144813575,0.00002156399,0.0005220112,2.0303742e-7],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038269213,0.0012512909,0.00079678494,0.12875798,0.0031135883,0.000048296726,0.0035490328,0.00020838306,0.3506073,0.0004559969,0.025344338,0.48204008],"study_design_scores_gemma":[0.0037712636,0.0061760154,0.00028975387,0.040096298,0.00066375,0.000048890804,0.0006324238,0.0000105209165,0.10522116,0.0010070661,0.8413396,0.00074327353],"about_ca_topic_score_codex":0.00032338387,"about_ca_topic_score_gemma":0.003432024,"teacher_disagreement_score":0.8159953,"about_ca_system_score_codex":0.000103922466,"about_ca_system_score_gemma":0.0016763671,"threshold_uncertainty_score":0.99941},"labels":[],"label_agreement":null},{"id":"W582888628","doi":"10.1016/j.ejphar.2015.06.026","title":"In-vivo pharmacology of Trace-Amine Associated Receptor 1","year":2015,"lang":"en","type":"review","venue":"European Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Dopamine receptor; Dopamine; Receptor; Pharmacology; Neurotransmission; Neuroscience; Dopamine receptor D3; Regulator; Chemistry; Biology; Biochemistry","score_opus":0.04104769568851614,"score_gpt":0.3467293641435474,"score_spread":0.30568166845503125,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W582888628","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0028558138,0.9905402,0.000080098675,0.0000646047,0.0052004503,0.00033574938,0.00008642224,0.000005040761,0.0008316223],"genre_scores_gemma":[0.00079417916,0.99500585,0.00034962513,0.00018470353,0.0025100822,0.000006070794,0.00003880554,0.00011719666,0.0009934778],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9941577,0.0030438292,0.0017787645,0.00035088748,0.00024640368,0.0004224185],"domain_scores_gemma":[0.99675554,0.00008178802,0.0023738812,0.00014458707,0.00044167755,0.00020250116],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0025489922,0.0004453576,0.0018672959,0.0003945882,0.000030120018,0.000009652896,0.00080114143,0.00028844166,0.0025051783],"category_scores_gemma":[0.00012486552,0.0003819447,0.00064322405,0.00028325993,0.00011852024,0.000010558242,0.00019463999,0.000771655,0.000033009565],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024481118,0.0005008172,0.0000019146178,0.0011083583,0.001340677,0.0005035781,0.000100048026,0.000048192538,0.5749203,0.0000043547284,0.29885626,0.122370705],"study_design_scores_gemma":[0.0019947307,0.0013808848,3.2650064e-7,0.0005995207,0.0008054333,0.00022158933,0.000019690746,0.0000025509678,0.039850846,0.0000028570794,0.9548265,0.00029511636],"about_ca_topic_score_codex":0.0000012402236,"about_ca_topic_score_gemma":6.5299866e-7,"teacher_disagreement_score":0.6559702,"about_ca_system_score_codex":0.00010739745,"about_ca_system_score_gemma":0.0005770953,"threshold_uncertainty_score":0.99986327},"labels":[],"label_agreement":null},{"id":"W59199282","doi":"10.1139/y10-052","title":"β-arrestin-1 mediates the endothelin-1-induced activation of Akt and integrin-linked kinaseThis article is one of a selection of papers published in the two-part special issue entitled 20 Years of Endothelin Research.","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":true,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Ministero della Salute","keywords":"Protein kinase B; Integrin-linked kinase; Cell biology; PI3K/AKT/mTOR pathway; Phosphorylation; Autocrine signalling; GSK-3; Cancer research; Arrestin; Chemistry; Kinase; Signal transduction; Biology; Protein kinase A; G protein-coupled receptor; Receptor; Biochemistry; Cyclin-dependent kinase 2","score_opus":0.021425791570719405,"score_gpt":0.294625874486822,"score_spread":0.2732000829161026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W59199282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987485,0.00010646331,0.0000034740324,0.0005670252,0.00034655654,0.0001262152,0.000022934351,3.271759e-7,0.00007850383],"genre_scores_gemma":[0.99892884,0.00012716647,0.00007271204,0.00012513611,0.00071324,0.000003610755,0.00000418672,0.0000054882353,0.000019603314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989584,0.0003540547,0.00033723228,0.00010842113,0.00008676275,0.0001551084],"domain_scores_gemma":[0.9991064,0.00022051428,0.00027938324,0.00008101108,0.00024282599,0.000069845606],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0010713874,0.000065838765,0.00020974253,0.0001395376,0.000044815948,0.0000042662314,0.00017405019,0.00013092728,0.0035052334],"category_scores_gemma":[0.00026192755,0.00004789655,0.000046940637,0.000120810124,0.00034581003,0.000010276582,0.000019309056,0.00038420162,2.628837e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022053257,0.000046030105,0.000534751,0.000022528398,0.00007354172,0.00000100105,0.0009952048,0.000016412218,0.99605745,0.00009847342,0.00045042645,0.0014836744],"study_design_scores_gemma":[0.0007790524,0.0004886201,0.0016631869,0.000013055467,0.00002799638,0.00000886265,0.00034627007,0.000036802983,0.99391335,0.0007047395,0.0019796165,0.00003846281],"about_ca_topic_score_codex":0.0009342267,"about_ca_topic_score_gemma":0.0019753652,"teacher_disagreement_score":0.0035049706,"about_ca_system_score_codex":0.000006848504,"about_ca_system_score_gemma":0.00029794237,"threshold_uncertainty_score":0.9974057},"labels":[],"label_agreement":null},{"id":"W597642536","doi":"10.1139/y05-150","title":"Differential changes in β-adrenoceptor signal transduction in left and right ventricles of infarcted ratsThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.","year":2006,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Ventricle; Heart failure; Adenylyl cyclase; Internal medicine; Cardiology; Medicine; Signal transduction; Inotrope; Myocardial infarction; Downregulation and upregulation; Endocrinology; Receptor; Biology; Cell biology","score_opus":0.004971888333484654,"score_gpt":0.21132796970468604,"score_spread":0.20635608137120137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W597642536","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99883366,0.00038567258,0.0000045444663,0.00026013088,0.00026335148,0.000099795325,0.000029233775,3.6227127e-7,0.00012325338],"genre_scores_gemma":[0.9990584,0.00048392644,0.00004107838,0.000050530587,0.00030235443,0.000002331958,0.000019470597,0.0000048615047,0.000037007303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992528,0.00009303694,0.0003284393,0.00014184724,0.00005074947,0.00013311919],"domain_scores_gemma":[0.99959314,0.00001573098,0.00021055844,0.000025188265,0.00009732335,0.000058038644],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014012888,0.00009038959,0.00028068584,0.0002881319,0.00001872374,0.000004810362,0.00006390835,0.00016089887,0.78704244],"category_scores_gemma":[0.000007955542,0.00008835499,0.000029910761,0.00008128906,0.00016351092,0.000018528332,0.000010080363,0.00015069298,5.6345854e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037062287,0.00005597383,0.004014075,0.000054086584,0.00006385882,0.0000031346763,0.00041819012,0.000010912535,0.99397117,0.00001475096,0.00030924025,0.00071395695],"study_design_scores_gemma":[0.0015057037,0.00032004132,0.011131843,0.00002736995,0.000020635685,0.000012500394,0.000085747764,0.000045506826,0.984967,0.00030789475,0.0015051787,0.00007056907],"about_ca_topic_score_codex":0.0010949804,"about_ca_topic_score_gemma":0.010488607,"teacher_disagreement_score":0.78704244,"about_ca_system_score_codex":0.000019227644,"about_ca_system_score_gemma":0.00014631795,"threshold_uncertainty_score":0.5852889},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":["insufficient_payload"],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"split"},{"id":"W62323985","doi":"10.1007/978-94-007-4765-4_4","title":"The Functional Size of GPCRs – Monomers, Dimers or Tetramers?","year":2012,"lang":"en","type":"review","venue":"Sub-cellular biochemistry/Subcellular biochemistry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Receptor; Context (archaeology); Dimer; Allosteric regulation; Monomer; Order (exchange); Computational biology; Chemistry; Biology; Biochemistry; Business","score_opus":0.02627298111946049,"score_gpt":0.25580850136087774,"score_spread":0.22953552024141724,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W62323985","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007880996,0.9880919,0.0007647193,0.00002413508,0.0011231145,0.00090127793,0.00039880033,0.00007051775,0.0007445663],"genre_scores_gemma":[0.020415531,0.9603281,0.0004953951,0.000035631154,0.0024342528,0.00029594282,0.0044523915,0.00042215816,0.011120617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99275464,0.00027954945,0.0021522874,0.0020324844,0.0010790001,0.0017020585],"domain_scores_gemma":[0.99379134,0.00036628355,0.001834482,0.0028909286,0.00037199794,0.00074497756],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.0012816935,0.0019224547,0.002176342,0.00010418832,0.0006235333,0.00017830673,0.0020237095,0.0025581075,0.0005959161],"category_scores_gemma":[0.00064756395,0.0014506981,0.0024378125,0.0007191069,0.0009793057,0.000014779876,0.00079879694,0.0011932825,0.000084676314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019391908,0.00027318756,0.0000053649214,0.0071308813,0.001294521,0.00002551673,0.000013667583,0.0000037565198,0.88986397,0.000012635629,0.002524567,0.09865801],"study_design_scores_gemma":[0.00039296073,0.000084759246,1.11442596e-7,0.00082288875,0.0007287928,0.00010267271,0.00012425252,0.000003431787,0.5717284,0.0000072187154,0.42499763,0.0010068627],"about_ca_topic_score_codex":0.000018281029,"about_ca_topic_score_gemma":0.000002310283,"teacher_disagreement_score":0.42247304,"about_ca_system_score_codex":0.0002548876,"about_ca_system_score_gemma":0.0017058853,"threshold_uncertainty_score":0.9993519},"labels":[],"label_agreement":null},{"id":"W646803347","doi":"10.1016/bs.mie.2014.12.017","title":"Ion Channel Reporter for Monitoring the Activity of Engineered GPCRs","year":2015,"lang":"en","type":"article","venue":"Methods in enzymology on CD-ROM/Methods in enzymology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Agence Nationale de la Recherche","keywords":"G protein-coupled receptor; Ion channel; Chemistry; Xenopus; Receptor; Biophysics; Ligand-gated ion channel; Biochemistry; Biology","score_opus":0.08736648618564795,"score_gpt":0.41752703603668073,"score_spread":0.33016054985103277,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W646803347","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5649214,0.0008393296,0.4295933,0.00021982775,0.0033235953,0.00067884184,0.000011262667,0.00002417418,0.000388258],"genre_scores_gemma":[0.4380271,0.00007461058,0.56068665,0.00014644518,0.00043527645,0.0003370948,0.000016008938,0.00006315527,0.0002136681],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9920393,0.004871984,0.0010239129,0.0010241148,0.00019304152,0.0008476453],"domain_scores_gemma":[0.99642146,0.0016905344,0.0005179345,0.0010104829,0.0002133649,0.00014624355],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.012865674,0.000479921,0.0010115418,0.00040931287,0.00008599915,0.000014150611,0.00066135544,0.0010851953,0.000025207004],"category_scores_gemma":[0.0049876226,0.00040477756,0.0002761229,0.00041818974,0.00031287246,0.000013883584,0.00028068305,0.0006334697,0.0000015458203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007540438,0.00023703376,0.00086226425,0.00003905928,0.00009168403,0.000023983117,0.0005008289,0.0026064399,0.9682053,0.0008598815,0.00018521742,0.025634265],"study_design_scores_gemma":[0.0018099359,0.0016934761,0.0053066467,0.000043646916,0.000040360545,0.00015274904,0.00041236664,0.00055159145,0.97217935,0.013250638,0.0041154227,0.00044381904],"about_ca_topic_score_codex":0.00013583543,"about_ca_topic_score_gemma":0.00008653317,"teacher_disagreement_score":0.13109332,"about_ca_system_score_codex":0.00011582972,"about_ca_system_score_gemma":0.00016797181,"threshold_uncertainty_score":0.99984044},"labels":[],"label_agreement":null},{"id":"W647659435","doi":"10.1016/j.biopsych.2015.05.020","title":"Mice Lacking GPR88 Show Motor Deficit, Improved Spatial Learning, and Low Anxiety Reversed by Delta Opioid Antagonist","year":2015,"lang":"en","type":"article","venue":"Biological Psychiatry","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut Universitaire en Santé Mentale de Québec","funders":"National Institute on Drug Abuse; National Institute on Alcohol Abuse and Alcoholism","keywords":"Naltrindole; Striatum; Morris water navigation task; Neuroscience; Motor coordination; Elevated plus maze; Rotarod performance test; Psychology; Opioid; Pharmacology; Opioid receptor; Medicine; Hippocampus; Endocrinology; Anxiety; Dopamine; Receptor; Internal medicine; Psychiatry","score_opus":0.011974666587378929,"score_gpt":0.24049731721662174,"score_spread":0.22852265062924282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W647659435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99052477,0.0032868786,0.0044511924,0.00016070019,0.0008498576,0.00023768176,0.00006620587,0.000046645542,0.0003760639],"genre_scores_gemma":[0.9933271,0.00062240876,0.004078507,0.00051208143,0.0006640215,0.000016252936,0.00037574777,0.000025726391,0.00037817672],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985342,0.00012692435,0.00026129684,0.0006034796,0.000110324494,0.00036374814],"domain_scores_gemma":[0.99937326,0.000011363233,0.00013312543,0.00017668786,0.000072784205,0.00023276887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031905575,0.00025693444,0.00023277893,0.000020763267,0.0001624488,0.000061024733,0.00019143477,0.00043308365,0.000061009425],"category_scores_gemma":[0.00012297096,0.00020437677,0.00011420963,0.000057605936,0.00010422142,0.0000054446887,0.0001490162,0.00023153645,0.000008880803],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002732509,0.000082870945,0.037036292,0.000016133965,0.000029569106,7.057741e-7,0.00001564978,0.000003489364,0.9567945,0.000057393547,0.0032722042,0.0024179139],"study_design_scores_gemma":[0.0101088,0.010881398,0.009377681,0.00014137826,0.00013180668,0.00015723848,0.0025693933,0.0041324934,0.33319756,0.0017412703,0.62399983,0.003561129],"about_ca_topic_score_codex":0.000092465365,"about_ca_topic_score_gemma":0.000029833436,"teacher_disagreement_score":0.62359697,"about_ca_system_score_codex":0.00001646648,"about_ca_system_score_gemma":0.0000831069,"threshold_uncertainty_score":0.83342427},"labels":[],"label_agreement":null},{"id":"W651626263","doi":"10.1096/fasebj.26.1_supplement.lb530","title":"Effect of early diabetes on the expression of alpha‐1 adrenoceptors in aorta of Wistar Kyoto and Spontaneously Hypertensive rats","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Consejo Nacional de Ciencia y Tecnología; Swine Innovation Porc","keywords":"Alpha (finance); Endocrinology; Internal medicine; Diabetes mellitus; Receptor; Adrenergic receptor; Medicine; Alpha-2 adrenergic receptor; Adrenergic; Blood pressure; Surgery","score_opus":0.007117197136849794,"score_gpt":0.22098977206949982,"score_spread":0.21387257493265002,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W651626263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99846524,0.0012273581,0.000014427712,0.000023021585,0.000098143224,0.00012029956,0.0000065751165,6.9275046e-7,0.00004424415],"genre_scores_gemma":[0.9996693,0.0001340286,0.000042527117,0.000031499112,0.00009204491,0.0000022662086,0.0000021038675,0.0000094514,0.000016755677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99916804,0.00025428785,0.00021417532,0.00007241001,0.00013785047,0.00015325405],"domain_scores_gemma":[0.9994145,0.00013575472,0.00020547172,0.00014652248,0.000052379266,0.00004535853],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00080148724,0.00009642741,0.00019239275,0.000031633557,0.000046822784,0.000005607391,0.00013924165,0.00006247372,0.000044956167],"category_scores_gemma":[0.000102411934,0.00004764213,0.000076188466,0.00004027295,0.000080781,0.000005296477,0.00004226006,0.0001216592,3.9258174e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002553675,0.000025653202,0.009983944,0.000016050135,0.000026753918,0.0000016615072,0.00030603138,0.000017025945,0.98863703,0.000018877476,0.000048071153,0.00066354347],"study_design_scores_gemma":[0.00027787645,0.0011591001,0.0012056016,0.00011272277,0.000023409166,0.00002607141,0.00017820222,0.000008698366,0.9969057,0.000024187437,0.000027266016,0.000051164207],"about_ca_topic_score_codex":0.000012957816,"about_ca_topic_score_gemma":0.0000014589632,"teacher_disagreement_score":0.008778342,"about_ca_system_score_codex":0.0000043816303,"about_ca_system_score_gemma":0.000015773314,"threshold_uncertainty_score":0.19427897},"labels":[],"label_agreement":null},{"id":"W6884323378","doi":"10.1021/acs.jcim.0c00890.s001","title":"Structural Assessment of Agonist Efficacy in the μ‑Opioid\\nReceptor: Morphine and Fentanyl Elicit Different Activation Patterns","year":2021,"lang":"en","type":"article","venue":"Figshare","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Fentanyl; Morphine; Agonist; Opioid; μ-opioid receptor; G protein-coupled receptor; Opioid receptor; Receptor","score_opus":0.023390637254397797,"score_gpt":0.2831349892763028,"score_spread":0.25974435202190505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6884323378","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99391174,0.00013759738,0.00002550074,0.00006197463,0.000036903173,0.00012789012,0.005620554,0.0000029294886,0.00007491616],"genre_scores_gemma":[0.9662071,0.000020047131,0.000060196064,0.00011093936,0.000097531825,0.000028330898,0.03344085,0.000008812493,0.000026181473],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993828,0.000052299838,0.00014209769,0.00018830421,0.0001245204,0.00010995893],"domain_scores_gemma":[0.99966633,0.000025037134,0.0000698802,0.00016658136,0.000047571175,0.000024576202],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00003164427,0.000100410136,0.000105896885,0.000015529879,0.000044869867,0.000035682773,0.00010224612,0.00006651946,0.008464124],"category_scores_gemma":[0.00007176316,0.000072412884,0.000046677796,0.00004509528,0.0000041455564,0.0000036129652,0.00008293202,0.00008473154,0.0000014367868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009981849,0.00006098829,0.0028527305,0.000089053625,0.000024004496,0.000003358152,0.00014192838,0.00004455085,0.991243,0.00003315561,0.001954335,0.0035428829],"study_design_scores_gemma":[0.0005175412,0.00010772923,0.18216819,0.00026876535,0.000006648742,0.000007924526,0.00024249905,0.00033013517,0.81311715,0.000024023584,0.0030699763,0.00013944038],"about_ca_topic_score_codex":0.000009449885,"about_ca_topic_score_gemma":0.00002482348,"teacher_disagreement_score":0.17931545,"about_ca_system_score_codex":0.000011596134,"about_ca_system_score_gemma":0.0000291646,"threshold_uncertainty_score":0.99244225},"labels":[],"label_agreement":null},{"id":"W6903344019","doi":"10.1051/jbio/2022007/pdf","title":"Le récepteur de l’insuline a 50 ans – Revue des progrès accomplis","year":2022,"lang":"fr","type":"article","venue":"Springer Link (Chiba Institute of Technology)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Poison control; Arginine kinase; Circumstantial evidence","score_opus":0.015523051971683792,"score_gpt":0.23454057670435016,"score_spread":0.21901752473266636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6903344019","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9375037,0.03190162,0.015441863,0.007365386,0.0024662092,0.0007189218,0.00019905562,0.00019571006,0.004207517],"genre_scores_gemma":[0.9063852,0.0021007312,0.088133805,0.00020333426,0.00063200464,0.00019229943,0.0001253968,0.00008619402,0.0021410293],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975191,0.0000691729,0.0006397229,0.00078179187,0.00020222377,0.0007879904],"domain_scores_gemma":[0.9984461,0.0000071402656,0.00035209153,0.0008829927,0.00017225047,0.00013940496],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00051462295,0.00039702235,0.0005069059,0.00035766582,0.0006281121,0.00003614649,0.0010597067,0.00067969307,0.00029588625],"category_scores_gemma":[0.00016359621,0.00049909996,0.00028947933,0.000642315,0.0009306061,0.000027510854,0.001348233,0.0008882904,0.00001682511],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009705048,0.00054539996,0.001811107,0.00034646163,0.00026835644,0.000061669976,0.00016146158,0.002412258,0.83892715,0.072534636,0.0003502766,0.08248414],"study_design_scores_gemma":[0.00075692084,0.0007234294,0.000100029676,0.00012910436,0.00007177737,0.00024864695,0.0002912147,0.0002215094,0.3479739,0.003200469,0.64587516,0.0004078196],"about_ca_topic_score_codex":0.00025593082,"about_ca_topic_score_gemma":0.00012387702,"teacher_disagreement_score":0.6455249,"about_ca_system_score_codex":0.00012532317,"about_ca_system_score_gemma":0.0006552031,"threshold_uncertainty_score":0.9997461},"labels":[],"label_agreement":null},{"id":"W6906331080","doi":"10.17605/osf.io/ugcbv","title":"A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor","year":2024,"lang":"en","type":"article","venue":"OSF Preprints (OSF Preprints)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Peptide; Vasopressin; Receptor; Vasopressin receptor; Peptide hormone; Peptide sequence","score_opus":0.011799051388991583,"score_gpt":0.2425817292248409,"score_spread":0.2307826778358493,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6906331080","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98172915,0.000055011158,0.001461533,0.0007145484,0.0008952074,0.0008773566,0.000056251207,0.000054578904,0.014156343],"genre_scores_gemma":[0.8977009,0.000101920625,0.0019125317,0.00030299684,0.0008192273,0.00015100147,0.00007811766,0.000071467875,0.09886183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99684256,0.00051657006,0.00051883305,0.0014251955,0.00035428512,0.00034258224],"domain_scores_gemma":[0.99701256,0.0001832742,0.0002053316,0.0022905786,0.00010485344,0.00020341741],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0013447816,0.00031451767,0.00027769472,0.00003449522,0.0001742425,0.00017649274,0.0012376057,0.00027895442,0.11736282],"category_scores_gemma":[0.0021141488,0.00021985924,0.0003286023,0.00017496549,0.0001751148,0.000019272347,0.0013822387,0.0004097793,0.034253348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001977294,0.00007607579,0.0011072198,0.00003886494,0.00018590532,0.000007829434,0.00084944215,0.00014545828,0.93726,0.00009487357,0.050278477,0.009758132],"study_design_scores_gemma":[0.000386916,0.0000051700313,0.0006520783,0.000289166,0.000082474035,0.000026335629,0.0001467835,0.00031580337,0.8668943,0.00095781585,0.13000175,0.00024138208],"about_ca_topic_score_codex":0.0005787048,"about_ca_topic_score_gemma":0.00009117981,"teacher_disagreement_score":0.08470549,"about_ca_system_score_codex":0.000047588816,"about_ca_system_score_gemma":0.00063583103,"threshold_uncertainty_score":0.9664986},"labels":[],"label_agreement":null},{"id":"W6930021547","doi":"10.5281/zenodo.12080204","title":"c++ pour les nuls pdf gratuit","year":2024,"lang":"fr","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Filter (signal processing); Limiting; Nucleofection; Pretext","score_opus":0.02226679663371084,"score_gpt":0.2381822355224971,"score_spread":0.21591543888878625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930021547","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012568207,0.005388526,0.0114428075,0.0008114956,0.0007156826,0.00052327017,0.00045787144,0.00028475473,0.97911876],"genre_scores_gemma":[0.03517901,0.0016526827,0.0008953998,0.00019029896,0.0022379374,1.1124789e-7,0.00449245,0.009146669,0.94620544],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975301,0.00037556552,0.0003411454,0.0008922291,0.00031724724,0.00054370455],"domain_scores_gemma":[0.99862885,0.000008523832,0.00015256558,0.00059252244,0.00037380806,0.0002437018],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000507752,0.0003800618,0.00027595874,0.00021672492,0.00096410903,0.0009452818,0.0010520394,0.0004873106,0.44947395],"category_scores_gemma":[0.00034378725,0.00040062386,0.00020422525,0.0002768164,0.00019079937,0.0000098645705,0.0013623231,0.00049846666,0.13082026],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032466356,0.00009285969,3.8841122e-7,0.00027089362,0.00020720556,0.000028693652,0.00017839893,0.000017713332,0.20810221,0.008736104,0.6945789,0.08775415],"study_design_scores_gemma":[0.00030937503,0.00035033753,0.000005041031,0.00023244107,0.000068000234,0.0001385243,0.00026831136,0.000092245005,0.01879256,0.0005677298,0.9787535,0.00042189707],"about_ca_topic_score_codex":0.000021321086,"about_ca_topic_score_gemma":0.0000014237917,"teacher_disagreement_score":0.3186537,"about_ca_system_score_codex":0.00012323105,"about_ca_system_score_gemma":0.000014075244,"threshold_uncertainty_score":0.99984455},"labels":[],"label_agreement":null},{"id":"W6931458459","doi":"10.5281/zenodo.6795904","title":"thanneken/TheologicalQuestions: v2022","year":2022,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Mary's University","funders":"","keywords":"Identification (biology); Process (computing); Term (time); Work (physics)","score_opus":0.022008227295897326,"score_gpt":0.23764268025130963,"score_spread":0.2156344529554123,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931458459","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017927359,0.0012062074,0.004983189,0.00017338745,0.0002465096,0.00044669883,0.0005311876,0.00057732756,0.99165624],"genre_scores_gemma":[0.017576084,0.0024806364,0.0013390173,0.0006912146,0.0017197876,7.123006e-7,0.038645048,0.018045876,0.9195016],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984334,0.00035158134,0.00016197692,0.0005226277,0.00025063637,0.0002797764],"domain_scores_gemma":[0.99915797,0.0000043966893,0.00012773831,0.0005023067,0.00009942906,0.000108183194],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00040008052,0.00018472296,0.00015392591,0.00016136988,0.001007038,0.00018993278,0.00090003025,0.0001814898,0.34938326],"category_scores_gemma":[0.00026381487,0.00019133004,0.000089030706,0.00018430721,0.00009238812,0.0000032626644,0.0015039431,0.00026625177,0.0022680748],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022777609,0.000064083804,3.4971987e-7,0.00002495774,0.00006108922,0.000007653657,0.000034145316,0.000018824881,0.016769666,0.0028937142,0.96680117,0.013301543],"study_design_scores_gemma":[0.0002062092,0.00034133147,0.0000034090774,0.000015911322,0.000013640353,0.000057990877,0.00008760972,0.000015093881,0.00093756715,0.00012516131,0.9979711,0.00022498598],"about_ca_topic_score_codex":0.000011841283,"about_ca_topic_score_gemma":3.5048694e-7,"teacher_disagreement_score":0.3471152,"about_ca_system_score_codex":0.000046090805,"about_ca_system_score_gemma":0.00000432063,"threshold_uncertainty_score":0.99850875},"labels":[],"label_agreement":null},{"id":"W6931528930","doi":"10.5281/zenodo.7843135","title":"Modelling and simulating age-dependent pedestrian behaviour with an autonomous vehicle","year":2023,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Pedestrian; Order (exchange); Work (physics); Autonomous system (mathematics)","score_opus":0.03213574260295659,"score_gpt":0.24589538339108122,"score_spread":0.21375964078812462,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931528930","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.28832266,0.0016555164,0.15835935,0.00023140013,0.0006602561,0.0037401794,0.0014562209,0.0071168873,0.5384575],"genre_scores_gemma":[0.8509439,0.00060993293,0.0031746125,0.0000709051,0.0010433117,2.4612405e-7,0.0046553886,0.025927331,0.113574326],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99874824,0.00012220218,0.00014832137,0.0005188672,0.0001979799,0.00026438755],"domain_scores_gemma":[0.9993049,0.000003926046,0.00010976139,0.00033885462,0.00009502125,0.00014752902],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002740121,0.00018216649,0.00014837425,0.0001200003,0.00061053754,0.00039547423,0.00034685276,0.00017097699,0.0020047268],"category_scores_gemma":[0.000041893974,0.00018197348,0.000029905787,0.000101396145,0.00006070737,0.000008752554,0.0004146704,0.0001764678,0.00024149052],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011103089,0.0010969054,0.000096195894,0.001061069,0.0013591247,0.0007733143,0.0041495957,0.1442998,0.24816212,0.0023435622,0.2390785,0.35646948],"study_design_scores_gemma":[0.00089812506,0.001118522,0.000012967821,0.00013144966,0.00005350675,0.000067640416,0.000408102,0.011066155,0.002909663,0.00004316997,0.9827287,0.0005619571],"about_ca_topic_score_codex":0.00013837033,"about_ca_topic_score_gemma":0.000009298558,"teacher_disagreement_score":0.74365026,"about_ca_system_score_codex":0.000026965345,"about_ca_system_score_gemma":0.00000492042,"threshold_uncertainty_score":0.99890757},"labels":[],"label_agreement":null},{"id":"W6931822635","doi":"10.5281/zenodo.6869765","title":"Sorex monticolus Merriam 1890","year":2018,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Subspecies; Shrew; Sorex; Subgenus; Holotype; Taxonomy (biology)","score_opus":0.022221287014699508,"score_gpt":0.2422431147319537,"score_spread":0.2200218277172542,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931822635","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60563457,0.00045915047,0.07772759,0.00077017787,0.00083977194,0.00091780355,0.00019506412,0.000721024,0.31273487],"genre_scores_gemma":[0.9950484,0.00006203672,0.0007599241,0.00020875114,0.0007064733,3.3228705e-8,0.00065647584,0.0007383834,0.0018195442],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99892414,0.00013036361,0.00015026641,0.00034068446,0.00017837032,0.00027617576],"domain_scores_gemma":[0.9990838,0.0000026990238,0.00005627948,0.00034987263,0.00038487086,0.00012245243],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00035947995,0.00010531208,0.00008671975,0.0000643158,0.0011566255,0.00026874925,0.0005298374,0.0000803492,0.010703894],"category_scores_gemma":[0.00022187212,0.00010897149,0.000050898427,0.00015677913,0.00012610796,0.000009425328,0.0005986962,0.000091061425,0.0030525376],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007290741,0.000058656864,0.0000022381776,0.000011088722,0.00004147506,0.0000027048652,0.00022081027,0.000010070015,0.79035664,0.001522411,0.16434439,0.043356624],"study_design_scores_gemma":[0.00028906498,0.00046740056,0.00009453904,0.0000076116776,0.00000727381,0.00003390139,0.000086781714,0.00017951304,0.11451468,0.00013722679,0.8840495,0.00013253409],"about_ca_topic_score_codex":0.000009486573,"about_ca_topic_score_gemma":5.4790416e-7,"teacher_disagreement_score":0.7197051,"about_ca_system_score_codex":0.000023486158,"about_ca_system_score_gemma":0.0000033320634,"threshold_uncertainty_score":0.9977237},"labels":[],"label_agreement":null},{"id":"W6932069408","doi":"10.5683/sp3/nvqd51","title":"Lac Peabody (East) Quebec. 1:50,000. Map Sheet 031O10, ed. 1, 1962","year":2022,"lang":"en","type":"dataset","venue":"Borealis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Georeference; General partnership; Raster graphics; Geographic information system; Aerial photography; Viewshed analysis; Natural (archaeology); Digital mapping","score_opus":0.00909118598457053,"score_gpt":0.2384390693703559,"score_spread":0.22934788338578535,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6932069408","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000077520854,0.0025876656,0.000086606655,0.00018453368,0.00095757307,0.00033224025,0.9952661,0.00003209211,0.00047570348],"genre_scores_gemma":[0.000032940352,0.0011137858,0.00014434173,0.00085560145,0.0014788471,0.0001606731,0.99284816,0.00008586126,0.0032798022],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9973194,0.00019988202,0.0004725357,0.00092852657,0.0004907738,0.00058886677],"domain_scores_gemma":[0.99804914,0.000015895459,0.0002879551,0.0013328486,0.00009037305,0.00022378445],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00038629794,0.0005583109,0.00049492135,0.000119937766,0.0002502395,0.0001162813,0.000933943,0.00061813963,0.02384229],"category_scores_gemma":[0.000069258254,0.00056096126,0.00034927842,0.00008991451,0.00007275389,0.000005140571,0.0006195023,0.00046872292,0.00003417267],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007832585,0.00009150828,0.0000024368092,0.00009381181,0.00014941838,0.000040044313,0.000021821807,0.00003153438,0.010683753,0.000049132934,0.988321,0.0004372111],"study_design_scores_gemma":[0.00035779332,0.0002539646,0.000008554611,0.000029473238,0.00011194465,0.000021523982,0.000098538156,0.000004188949,0.003730857,0.000045164103,0.9946756,0.000662403],"about_ca_topic_score_codex":0.07132332,"about_ca_topic_score_gemma":0.025474476,"teacher_disagreement_score":0.045848846,"about_ca_system_score_codex":0.00009928529,"about_ca_system_score_gemma":0.00040915067,"threshold_uncertainty_score":0.9996842},"labels":[],"label_agreement":null},{"id":"W6939348599","doi":"10.6084/m9.figshare.26608527.v1","title":"Additional file 3 of Lack of HCAR1, the lactate GPCR, signaling promotes autistic-like behavior","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Signal transduction; Ubiquitin-Protein Ligases; Mechanism (biology); Key (lock)","score_opus":0.03757317868010054,"score_gpt":0.2736087376912872,"score_spread":0.23603555901118664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6939348599","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00090912037,0.00033669634,0.00000891928,0.000013765996,0.000043325283,0.00013391855,0.99806774,0.000011842735,0.00047466127],"genre_scores_gemma":[0.09560067,0.0000020187572,0.0006411732,0.00004517616,0.0001708657,0.00041319753,0.9015537,0.000023177057,0.0015500089],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993642,0.000025999489,0.00017326183,0.00018229993,0.00013300603,0.00012121614],"domain_scores_gemma":[0.9994917,0.00015777927,0.000075947704,0.00014979522,0.00009853898,0.00002624353],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000032365497,0.00009698843,0.000100293306,0.000021852089,0.00003993085,0.00002064706,0.0001526779,0.00008754724,0.9577258],"category_scores_gemma":[0.00039311437,0.00007232536,0.00011703754,0.00007473518,0.000014894491,0.0000034042582,0.00007525852,0.000077363686,0.00016965691],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000044253848,0.000016508322,3.4942335e-7,0.0000998711,0.00002640847,0.000004083457,0.000023186018,0.000008731655,0.10642098,0.000010443087,0.8923022,0.0010827914],"study_design_scores_gemma":[0.000045123008,0.00010886715,0.000045221124,0.0010940471,0.000016500588,0.000009011754,0.000036086105,0.00024291535,0.2488198,0.000045125016,0.749434,0.00010333376],"about_ca_topic_score_codex":0.0000018963655,"about_ca_topic_score_gemma":0.000001926628,"teacher_disagreement_score":0.9575562,"about_ca_system_score_codex":0.0000047504914,"about_ca_system_score_gemma":0.00010245037,"threshold_uncertainty_score":0.29493427},"labels":[],"label_agreement":null},{"id":"W6969253717","doi":"10.5683/sp2/kbx2p8","title":"Canadian Gallup Poll, September 1972, #355","year":2019,"lang":"en","type":"dataset","venue":"Borealis","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Voting; Politics; Control (management); Voting behavior; Ask price; Special Interest Group; Birth control","score_opus":0.011092135365628766,"score_gpt":0.2433741471779016,"score_spread":0.23228201181227282,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6969253717","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011147725,0.0005340091,0.000021492011,0.00007434976,0.0005088192,0.0002332483,0.9949506,0.00000679942,0.003559191],"genre_scores_gemma":[0.00018363797,0.00036861622,0.00007902099,0.001142747,0.00085043156,0.000023509088,0.99468035,0.00003852868,0.0026331597],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9984666,0.000056029643,0.0002452639,0.0005383307,0.0002020695,0.00049167406],"domain_scores_gemma":[0.9985184,0.0000064954666,0.00011975922,0.00095220126,0.00008261988,0.0003205423],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016236122,0.00034143473,0.00029981488,0.00011440524,0.00008860829,0.00006817374,0.00048439112,0.0007630595,0.0013562696],"category_scores_gemma":[0.000035487752,0.0003294269,0.00019776676,0.00005803332,0.000025970998,0.0000023028572,0.00010221969,0.00022154824,0.00020006974],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010712699,0.000012215569,0.000006460501,0.000037447287,0.00008581349,0.000016983533,0.0000030267486,0.000011879508,0.0035263044,0.000008468889,0.9961119,0.0001687584],"study_design_scores_gemma":[0.00018857389,0.00010622795,0.000015339245,0.00003407932,0.000052389674,0.000016341171,0.000011495337,0.000003322854,0.004659065,0.0000150010665,0.99447906,0.0004190936],"about_ca_topic_score_codex":0.5469968,"about_ca_topic_score_gemma":0.7196884,"teacher_disagreement_score":0.17269166,"about_ca_system_score_codex":0.000073760006,"about_ca_system_score_gemma":0.0006173891,"threshold_uncertainty_score":0.9999158},"labels":[],"label_agreement":null},{"id":"W6977164131","doi":"10.6084/m9.figshare.26608527","title":"Additional file 3 of Lack of HCAR1, the lactate GPCR, signaling promotes autistic-like behavior","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Signal transduction; Ubiquitin-Protein Ligases; Mechanism (biology); Key (lock)","score_opus":0.03757317868010054,"score_gpt":0.2736087376912872,"score_spread":0.23603555901118664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6977164131","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00090912037,0.00033669634,0.00000891928,0.000013765996,0.000043325283,0.00013391855,0.99806774,0.000011842735,0.00047466127],"genre_scores_gemma":[0.09560067,0.0000020187572,0.0006411732,0.00004517616,0.0001708657,0.00041319753,0.9015537,0.000023177057,0.0015500089],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993642,0.000025999489,0.00017326183,0.00018229993,0.00013300603,0.00012121614],"domain_scores_gemma":[0.9994917,0.00015777927,0.000075947704,0.00014979522,0.00009853898,0.00002624353],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000032365497,0.00009698843,0.000100293306,0.000021852089,0.00003993085,0.00002064706,0.0001526779,0.00008754724,0.9577258],"category_scores_gemma":[0.00039311437,0.00007232536,0.00011703754,0.00007473518,0.000014894491,0.0000034042582,0.00007525852,0.000077363686,0.00016965691],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000044253848,0.000016508322,3.4942335e-7,0.0000998711,0.00002640847,0.000004083457,0.000023186018,0.000008731655,0.10642098,0.000010443087,0.8923022,0.0010827914],"study_design_scores_gemma":[0.000045123008,0.00010886715,0.000045221124,0.0010940471,0.000016500588,0.000009011754,0.000036086105,0.00024291535,0.2488198,0.000045125016,0.749434,0.00010333376],"about_ca_topic_score_codex":0.0000018963655,"about_ca_topic_score_gemma":0.000001926628,"teacher_disagreement_score":0.9575562,"about_ca_system_score_codex":0.0000047504914,"about_ca_system_score_gemma":0.00010245037,"threshold_uncertainty_score":0.29493427},"labels":[],"label_agreement":null},{"id":"W6981238798","doi":"","title":"Do disparities in suicide-related behaviour across sexual orientations differ by neighbourhood deprivation? A discrete-time survival analysis in Ontario, Canada (2007-2017)","year":2022,"lang":"en","type":"other","venue":"Brock University Digital Repository (Brock University)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Odds; Neighbourhood (mathematics); Sexual orientation; Odds ratio; Sexual minority; Stressor; Disadvantage","score_opus":0.005608894493962831,"score_gpt":0.19184880533358933,"score_spread":0.18623991083962652,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6981238798","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94030166,0.00013121885,0.00045927992,0.000003847506,0.0003855661,0.00040186042,0.0017309312,0.000059004884,0.056526627],"genre_scores_gemma":[0.27222976,0.000017181026,0.000015280815,0.000009103929,0.000025637646,6.788183e-7,0.0028528548,0.00007196411,0.7247775],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977653,0.00014455334,0.0002901159,0.0008841237,0.000407915,0.0005079981],"domain_scores_gemma":[0.99895096,0.000032716085,0.00029784022,0.00045110582,0.0000616691,0.00020570612],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000007537535,0.000424721,0.0005133196,0.00054128846,0.00029074735,0.0001130035,0.00063161534,0.00041746083,0.0006264725],"category_scores_gemma":[0.000018251925,0.0005667451,0.00021820462,0.0008086214,0.00007596782,0.000062793595,0.0006069805,0.00044118927,0.000003369159],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016846207,0.00021200106,0.872727,0.000015846419,0.00061660475,0.00026695157,0.000043798416,0.00079173286,0.0067827464,0.000021490867,0.11833369,0.000019704292],"study_design_scores_gemma":[0.006855708,0.0006914703,0.37886134,0.00016494769,0.0016105127,0.00005428815,0.038486227,0.000025883232,0.0011138355,0.00002306842,0.56795645,0.00415627],"about_ca_topic_score_codex":0.7323308,"about_ca_topic_score_gemma":0.9715077,"teacher_disagreement_score":0.6682509,"about_ca_system_score_codex":0.0013293138,"about_ca_system_score_gemma":0.00071135943,"threshold_uncertainty_score":0.9996784},"labels":[],"label_agreement":null},{"id":"W6991859913","doi":"","title":"Investigating G protein- and β-arrestin-dependent bias at the dopamine D1 receptor in cellulo","year":2024,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Dopamine; Receptor; Dopamine receptor D1; Dopamine receptor; Dopamine receptor D2","score_opus":0.01785009601712143,"score_gpt":0.2361862023357695,"score_spread":0.21833610631864808,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6991859913","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98701775,0.004109895,2.0554832e-7,0.00003735123,0.0010715869,0.0010018867,0.00033913748,0.000056085933,0.006366083],"genre_scores_gemma":[0.96585006,0.00061956,0.0005438576,0.00015757109,0.00019429812,0.0003504378,0.0018716132,0.00023579289,0.030176815],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9963179,0.00037547664,0.0008079769,0.001329617,0.00054849376,0.00062052533],"domain_scores_gemma":[0.99848866,0.00007590204,0.00040361224,0.0006249756,0.00015823077,0.00024860716],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0012805043,0.0007130662,0.0004978148,0.00018322047,0.0006565121,0.000115912684,0.00048490035,0.0008471794,0.00026324615],"category_scores_gemma":[0.0008318821,0.00059172325,0.00021570614,0.0003053395,0.000086142114,0.000022233933,0.00039231137,0.0011971048,0.00013348261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007642889,0.000037653896,0.000026957192,0.0003362665,0.000085436375,0.000021977005,0.00001574509,0.000027498108,0.9795515,0.0017087883,0.000017940101,0.018093795],"study_design_scores_gemma":[0.00047750917,0.0002121707,0.00006901631,0.0007110762,0.00007327506,0.000024020866,0.0003875071,0.000023529656,0.95265424,0.0027388618,0.04189941,0.0007294003],"about_ca_topic_score_codex":0.00027493454,"about_ca_topic_score_gemma":0.002751792,"teacher_disagreement_score":0.04188147,"about_ca_system_score_codex":0.00021885017,"about_ca_system_score_gemma":0.000081714476,"threshold_uncertainty_score":0.9996534},"labels":[],"label_agreement":null},{"id":"W6999748591","doi":"","title":"Development and Validation of a Novel Quantitative Assay for Cell surface Expression of GPCRs using a Receptor Î²-lactamase fusion Protein and the Colourometric Substrate Nitrocefin","year":2013,"lang":"en","type":"dissertation","venue":"Library and Archives Canada (Government of Canada)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"G protein-coupled receptor; Receptor; Internalization; Substrate (aquarium); Cell; Cell membrane; Agonist; Fusion; Lipid bilayer fusion","score_opus":0.008998202028762095,"score_gpt":0.1837043959370746,"score_spread":0.17470619390831252,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6999748591","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970008,0.0007209081,0.00089994306,0.00003135515,0.00005763432,0.00061227847,0.00015848665,8.981514e-7,0.000517679],"genre_scores_gemma":[0.9677678,0.00016357601,0.03063402,0.000017011957,0.000010751814,0.000021771688,0.00017500586,0.000020296411,0.0011897676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872553,0.00006819677,0.00035120687,0.00023119706,0.0004909997,0.00013283882],"domain_scores_gemma":[0.9991653,0.00012649804,0.000538589,0.00008847059,0.000006477452,0.00007468878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059149133,0.00017783092,0.00027994113,0.000029883264,0.00011380866,0.000014316758,0.00008933325,0.000074633295,0.000006429108],"category_scores_gemma":[0.000016313492,0.00014030574,0.000027161332,0.00005968521,0.000048353733,0.000019106643,0.000051274023,0.00006766831,2.3852192e-10],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013694301,0.000027424316,0.0001090378,0.0005851456,0.000038437964,2.4511314e-7,0.00021488784,0.000055006734,0.9961731,0.001045418,0.000016447944,0.00036542554],"study_design_scores_gemma":[0.0009188569,0.00013260514,0.0002537355,0.00025983615,0.000027396514,4.348958e-7,0.0040953,0.0010447431,0.9928286,0.000049793038,0.00023852185,0.0001501762],"about_ca_topic_score_codex":0.0006585188,"about_ca_topic_score_gemma":0.00091718556,"teacher_disagreement_score":0.029734077,"about_ca_system_score_codex":0.0000036009383,"about_ca_system_score_gemma":0.00084334967,"threshold_uncertainty_score":0.5721502},"labels":[],"label_agreement":null},{"id":"W7008129070","doi":"","title":"Biased allosteric regulation of the Prostaglandin F2α receptor: from small molecules to large receptor complexes","year":2013,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; McGill University","keywords":"Allosteric regulation; G protein-coupled receptor; Receptor; Functional selectivity; Extracellular; Allosteric modulator; Signal transduction; Small molecule; Agonist; Intracellular","score_opus":0.015106322078426772,"score_gpt":0.22652847814477436,"score_spread":0.2114221560663476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7008129070","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99124974,0.00046028206,0.000012123992,0.000020926947,0.0015076809,0.0014702335,0.0034070893,0.000050683855,0.0018212101],"genre_scores_gemma":[0.97502834,0.0002293971,0.0037040177,0.00033534958,0.00018542475,0.00026253366,0.013620728,0.00023952604,0.006394694],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99619496,0.00047304333,0.0009533192,0.0011602918,0.0005935461,0.0006248498],"domain_scores_gemma":[0.9972561,0.000061258506,0.0008185533,0.0010787006,0.0005230961,0.00026231582],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004901379,0.00072743767,0.0006881956,0.00017410786,0.0005698232,0.000068482994,0.00091302604,0.00096355233,0.0010794335],"category_scores_gemma":[0.00044073362,0.00062455476,0.00048433786,0.00036155074,0.0000440421,0.00002695609,0.0002940685,0.0005369887,0.00016486202],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032742327,0.00012868448,0.00005545131,0.00010958983,0.00018840261,5.9790557e-7,0.000019055331,0.00004336642,0.99063516,0.00152192,0.00020822523,0.006762123],"study_design_scores_gemma":[0.00072970375,0.0002865546,0.0013582752,0.0003967289,0.00009416379,0.0000013909981,0.0002542585,0.000021067839,0.9190207,0.0011372473,0.07599189,0.00070800545],"about_ca_topic_score_codex":0.0004429968,"about_ca_topic_score_gemma":0.001023673,"teacher_disagreement_score":0.07578367,"about_ca_system_score_codex":0.0001438371,"about_ca_system_score_gemma":0.00006831191,"threshold_uncertainty_score":0.9998337},"labels":[],"label_agreement":null},{"id":"W7011146943","doi":"","title":"Les dimensions du retrait social à l'enfance : associations avec les difficultés interpersonnelles, étiologie génétique et précurseurs tempéramentaux","year":2021,"lang":"fr","type":"other","venue":"Corpus Université Laval (Université Laval)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Solitude; Social environment; Social relationship","score_opus":0.015093133206872122,"score_gpt":0.23803957337437404,"score_spread":0.22294644016750192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7011146943","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8382674,0.017071191,0.008251854,0.008375913,0.0027001714,0.0014090007,0.0019956673,0.00030609718,0.121622704],"genre_scores_gemma":[0.6927461,0.021301076,0.0014061134,0.0003675152,0.0009033834,0.000008394513,0.0032950132,0.0003334202,0.279639],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99595743,0.00078865304,0.00044608203,0.0014612696,0.00046554802,0.0008810385],"domain_scores_gemma":[0.9977297,0.00015131549,0.00075899315,0.0005624235,0.00044751208,0.00035003465],"candidate_categories":["metaepi_narrow","sts","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029647443,0.00095795514,0.0009789399,0.00031510598,0.0014971244,0.00012619435,0.00096087006,0.0019650108,0.0028207488],"category_scores_gemma":[0.00014595351,0.0011393976,0.000986807,0.00052308774,0.00035136842,0.000034303146,0.00093795377,0.0010434249,0.000020265696],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028801645,0.0007410298,0.010091852,0.00020093849,0.0023747073,0.0007468648,0.01633831,0.000309386,0.88930476,0.040898874,0.01826195,0.020443324],"study_design_scores_gemma":[0.004280531,0.0010784642,0.013021667,0.001124335,0.0017005412,0.0001638938,0.033228613,0.000392128,0.16111483,0.00019266261,0.7804488,0.0032535272],"about_ca_topic_score_codex":0.0060391854,"about_ca_topic_score_gemma":0.01788176,"teacher_disagreement_score":0.7621868,"about_ca_system_score_codex":0.0012563433,"about_ca_system_score_gemma":0.00072454347,"threshold_uncertainty_score":0.99980277},"labels":[],"label_agreement":null},{"id":"W7014644560","doi":"","title":"Regulation of the endocytic adaptor proteins [beta] arrestin and AP-2 during clathrin-mediated internalization of Angiotensin II type 1 receptor","year":2006,"lang":"en","type":"dissertation","venue":"eScholarship@McGill (McGill)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Internalization; Endocytic cycle; Receptor; Endocytosis; Arrestin; Signal transducing adaptor protein; Clathrin; Immune receptor; Phosphorylation","score_opus":0.007969239423427626,"score_gpt":0.20715428530246083,"score_spread":0.1991850458790332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7014644560","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972206,0.00061001023,0.0000052072364,0.0000058944106,0.00047518514,0.00068057847,0.00032398629,0.000022317352,0.00065625634],"genre_scores_gemma":[0.9960916,0.00017577944,0.0006492439,0.000022277594,0.0000920904,0.000022696893,0.0014377347,0.000095163574,0.0014134326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99781615,0.00019492833,0.00074189965,0.0005793746,0.00039634344,0.00027128466],"domain_scores_gemma":[0.9980319,0.000024430057,0.000912559,0.00041708423,0.0005200315,0.00009397216],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026868703,0.00038474207,0.0004359164,0.00011660845,0.00031174612,0.0000136245535,0.00029303026,0.0006090597,0.000060680864],"category_scores_gemma":[0.00038500724,0.00034414104,0.00020764991,0.00028822152,0.000059447655,0.000022722277,0.00014380536,0.00033467202,0.0000024228393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035346296,0.000053270036,0.00007340683,0.00024982152,0.00009366265,7.519446e-7,0.000010888193,0.00018784213,0.99653167,0.0008446893,0.000006098377,0.0015944279],"study_design_scores_gemma":[0.0006334847,0.00027918702,0.0018456327,0.000502304,0.00009626514,0.0000048883117,0.000048329013,0.000068903304,0.9937685,0.00029253092,0.0021277587,0.0003322299],"about_ca_topic_score_codex":0.00013883252,"about_ca_topic_score_gemma":0.00019093565,"teacher_disagreement_score":0.002763192,"about_ca_system_score_codex":0.00007301472,"about_ca_system_score_gemma":0.000060859795,"threshold_uncertainty_score":0.99990106},"labels":[],"label_agreement":null},{"id":"W7026937214","doi":"","title":"Biased allosteric regulation of the Prostaglandin F2Î± receptor: from small molecules to large receptor complexes","year":2013,"lang":"en","type":"other","venue":"Library and Archives Canada (Government of Canada)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Allosteric regulation; G protein-coupled receptor; Receptor; Functional selectivity; Extracellular; Signal transduction; Allosteric modulator; Small molecule; Agonist; Intracellular","score_opus":0.004233598678070442,"score_gpt":0.14688941240454462,"score_spread":0.14265581372647418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7026937214","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4349124,0.0039011878,0.003986292,0.003711171,0.0023972492,0.0034274282,0.012884977,0.000043305303,0.534736],"genre_scores_gemma":[0.46411273,0.00046265614,0.010041871,0.0019963714,0.0005386399,0.00005874019,0.00095496356,0.00036396857,0.52147007],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984525,0.00009297865,0.00026986795,0.00032361652,0.0006356497,0.00022541339],"domain_scores_gemma":[0.9991923,0.000029924453,0.00029906005,0.00033378505,0.0000012281641,0.0001436904],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000011126774,0.00024141725,0.0002854052,0.000022472974,0.000066546745,0.000015959982,0.00030118867,0.00009404177,0.000716913],"category_scores_gemma":[0.000005034869,0.00019218955,0.00005439832,0.000052085335,0.000043490603,0.0000060619486,0.00023591083,0.00007958629,1.9900659e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014017643,0.00001830209,0.0012272767,0.00008455221,0.000104329694,5.6416013e-7,0.000024875433,0.000014755184,0.93376064,0.0018248447,0.062029056,0.0007706488],"study_design_scores_gemma":[0.00023963195,0.000073840165,0.0016586006,0.00021826812,0.00001524125,3.0672635e-7,0.00023527656,0.00008469127,0.6276976,0.0000634267,0.36950433,0.00020882562],"about_ca_topic_score_codex":0.005668148,"about_ca_topic_score_gemma":0.02508063,"teacher_disagreement_score":0.30747527,"about_ca_system_score_codex":0.000003999643,"about_ca_system_score_gemma":0.00044992156,"threshold_uncertainty_score":0.9927091},"labels":[],"label_agreement":null},{"id":"W7037712822","doi":"","title":"Evolutionary Alternatives on the Road to a New Specificity in a G Protein-Coupled Receptor","year":2017,"lang":"en","type":"dissertation","venue":"TSpace (University of Toronto)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Danmarks Grundforskningsfond; National Research Foundation","keywords":"G protein-coupled receptor; Receptor; Ligand (biochemistry); Regulator; Signal transduction; G protein; Functional selectivity; Plasma protein binding","score_opus":0.015201077491031383,"score_gpt":0.2525582571087772,"score_spread":0.23735717961774583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7037712822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96829695,0.0006122094,0.00026585677,0.00045121732,0.00026757005,0.0006548625,0.000021392223,0.000007827776,0.029422138],"genre_scores_gemma":[0.8699857,0.00035275478,0.0015302068,0.000023592938,0.00022851126,0.000003044821,0.00023683588,0.00002451539,0.12761487],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9990807,0.00006058535,0.000092781025,0.0003784557,0.00020677561,0.00018067154],"domain_scores_gemma":[0.9991537,0.000008356528,0.00023593764,0.0004290518,0.00008628561,0.00008669465],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014063818,0.00019101457,0.00023267846,0.000035597554,0.00017022814,0.000016165626,0.00056041515,0.00023151391,0.0071236338],"category_scores_gemma":[0.000064017746,0.00018939664,0.0001436008,0.00002434971,0.000030577754,0.000011601314,0.00006253114,0.0001331107,0.000025306928],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014226203,0.00008948354,0.00002450327,0.000034875557,0.000105459345,0.000005591209,0.0047744173,0.00003511528,0.9655498,0.0005447222,0.0036083267,0.023805078],"study_design_scores_gemma":[0.0049132286,0.0047407364,0.16281223,0.0028000288,0.0001824799,0.000003989656,0.09314158,0.0006026364,0.61743516,0.00052673346,0.10984699,0.0029942207],"about_ca_topic_score_codex":0.07201628,"about_ca_topic_score_gemma":0.06424256,"teacher_disagreement_score":0.34811467,"about_ca_system_score_codex":0.00012582832,"about_ca_system_score_gemma":0.00018532449,"threshold_uncertainty_score":0.993784},"labels":[],"label_agreement":null},{"id":"W7100401841","doi":"","title":"GPC3 (GLYPICAN 3) ET A�PP (AMYLOID �- PRECURSOR PROTEIN).","year":2014,"lang":"en","type":"article","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Subject (documents); Term (time); Sequence (biology)","score_opus":0.006748751791649033,"score_gpt":0.2304778517833849,"score_spread":0.22372909999173587,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7100401841","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8778487,0.00021356672,0.06984548,0.00046260265,0.00020172837,0.0004014714,0.0000073124934,0.00005526495,0.050963916],"genre_scores_gemma":[0.9829529,0.00002564,0.007942343,0.0007810568,0.0002546516,0.00004449183,0.000051394833,0.000025133555,0.007922419],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991547,0.00007584185,0.00014194666,0.00029954183,0.000112707145,0.00021528247],"domain_scores_gemma":[0.99952585,0.0000057426964,0.000046794805,0.00028326467,0.00004921968,0.000089136396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028086963,0.00013034619,0.00011113661,0.000016007605,0.000055055894,0.000033394044,0.0001601115,0.00011745459,0.0004883339],"category_scores_gemma":[0.00006431649,0.00010800565,0.0000769144,0.000040029612,0.000024551753,0.0000026176883,0.000071073926,0.00007030111,0.000064896216],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023996061,0.000027085998,0.000049841645,0.0000073856604,0.000014826709,2.3367629e-7,0.00001500148,0.000011851092,0.98529124,0.007944596,0.0026271578,0.003986752],"study_design_scores_gemma":[0.00025063183,0.00029406243,0.000043319294,0.000007758362,0.0000042437823,0.000002895097,0.000019449955,0.00013689119,0.7826781,0.00062711426,0.21578602,0.00014945689],"about_ca_topic_score_codex":0.000019158468,"about_ca_topic_score_gemma":0.000021774322,"teacher_disagreement_score":0.21315886,"about_ca_system_score_codex":0.0000048478573,"about_ca_system_score_gemma":0.00003122586,"threshold_uncertainty_score":0.5346914},"labels":[],"label_agreement":null},{"id":"W7108214129","doi":"10.1101/2025.11.27.690850","title":"Reverse-engineering β-Arrestin Bias in the δ-Opioid Receptor","year":2025,"lang":"","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Functional selectivity; G protein-coupled receptor; Receptor; Signal transduction; Rational design; Drug discovery; Addiction; Drug design; Signaling proteins","score_opus":0.015236979038706624,"score_gpt":0.21882892263876672,"score_spread":0.20359194360006008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7108214129","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9730713,0.0082524745,0.0085900575,0.0005987108,0.006323837,0.0024046334,0.0005378725,0.0001531756,0.00006797847],"genre_scores_gemma":[0.98420036,0.003918016,0.008746473,0.0008727087,0.0016221907,0.0003989065,0.0000042030274,0.00016804966,0.00006910272],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99393076,0.0005822131,0.0013794855,0.0021233147,0.0006670676,0.0013171498],"domain_scores_gemma":[0.99582,0.00018441417,0.0006199712,0.0025619725,0.0004987028,0.00031493392],"candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.002529081,0.0012987765,0.0009986158,0.00044063592,0.00032190044,0.0004368361,0.0020072723,0.001634026,0.00023567185],"category_scores_gemma":[0.0012409351,0.0012441844,0.0005398351,0.0011429187,0.00014439307,0.000024642317,0.0009423217,0.0018100211,0.00008560521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000088001565,0.00021324286,0.0017148802,0.0006723903,0.00021859916,0.000040873907,0.000039666145,0.001319872,0.99298036,0.0009611436,0.0017408554,0.000010121759],"study_design_scores_gemma":[0.00088490185,0.00016472135,0.0031163814,0.001480736,0.00014880144,5.407855e-8,0.000033775756,0.0011062628,0.7969596,0.0000017466435,0.19463712,0.001465954],"about_ca_topic_score_codex":0.00013138166,"about_ca_topic_score_gemma":0.000008816728,"teacher_disagreement_score":0.1960208,"about_ca_system_score_codex":0.00021497121,"about_ca_system_score_gemma":0.0013151027,"threshold_uncertainty_score":0.9999764},"labels":[],"label_agreement":null},{"id":"W7117146354","doi":"10.1111/bph.70312","title":"Profiling of HCAR1 signalling reveals Gα <sub>i/o</sub> and Gα <sub>s</sub> activation without β‐arrestin recruitment and the discovery of an allosteric agonist","year":2025,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute for Research in Immunology and Cancer","funders":"Institute of Circulatory and Respiratory Health; Svenska Sällskapet för Medicinsk Forskning; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Novo Nordisk Fonden; Novo Nordisk; Stiftelsen för Strategisk Forskning; Karolinska Institutet; Vetenskapsrådet; Jeanssons Stiftelser; Natural Sciences and Engineering Research Council of Canada; Knut och Alice Wallenbergs Stiftelse; Ragnar Söderbergs stiftelse; AstraZeneca","keywords":"Allosteric regulation; Signalling; Profiling (computer programming); Agonist; Signalling pathways; Drug discovery; Signal transduction","score_opus":0.016237179372614197,"score_gpt":0.28489056408943886,"score_spread":0.26865338471682465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117146354","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910814,0.0033027858,0.004599589,0.0002090169,0.00030966816,0.00045444941,0.00001761892,0.0000030705098,0.000022359889],"genre_scores_gemma":[0.99470335,0.003890401,0.0008251434,0.00027967093,0.00023412338,0.000022158387,0.000017118742,0.000017898574,0.000010145009],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99831134,0.00040826527,0.0006674211,0.00024728285,0.00015960692,0.00020609752],"domain_scores_gemma":[0.99885404,0.000096975346,0.0006670378,0.00007485671,0.00024176078,0.000065323926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010653323,0.0001570736,0.0004303797,0.000083040075,0.00012590419,0.000056864665,0.00016974502,0.00013930368,0.0000033775445],"category_scores_gemma":[0.00011059119,0.00014429764,0.00010844228,0.00010270862,0.00022683613,0.000037349364,0.00011417907,0.00023342957,6.9144726e-8],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00083398964,0.00008992252,0.00026069162,0.000119850694,0.00022051083,0.000017973534,0.000052864973,0.00021221668,0.97751516,0.00004783974,0.00010468422,0.020524275],"study_design_scores_gemma":[0.00257081,0.00044228334,0.00048965047,0.00032244396,0.00018629627,0.00027540314,0.00012536078,0.00024842512,0.9947819,0.0003769137,0.00005777021,0.00012273352],"about_ca_topic_score_codex":0.000013218352,"about_ca_topic_score_gemma":0.000009234467,"teacher_disagreement_score":0.020401541,"about_ca_system_score_codex":0.000021112393,"about_ca_system_score_gemma":0.00014524933,"threshold_uncertainty_score":0.5884287},"labels":[],"label_agreement":null},{"id":"W7117551583","doi":"10.1111/bph.70230","title":"The Concise Guide to PHARMACOLOGY 2025/26: G protein‐coupled receptors","year":2025,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Université de Sherbrooke; Université de Montréal; University of Toronto","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; National Institute on Alcohol Abuse and Alcoholism; National Institute for Health and Care Excellence","keywords":"Scope (computer science); Clinical pharmacology; Identification (biology); Conjunction (astronomy); Action (physics); Drug discovery","score_opus":0.006960662763196128,"score_gpt":0.3039453196402757,"score_spread":0.2969846568770796,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117551583","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96167016,0.01198875,0.010324462,0.0046837325,0.009445925,0.00088078546,0.000010288976,0.000023003555,0.00097286224],"genre_scores_gemma":[0.9699355,0.0046056425,0.0026438215,0.00752751,0.0026715707,0.00012771452,0.000008244977,0.00006175643,0.012418248],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980225,0.00033700513,0.00072407594,0.00028085578,0.00017868864,0.00045689166],"domain_scores_gemma":[0.9988602,0.000078883,0.00030742868,0.00009527484,0.0004851704,0.00017309104],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011534962,0.00018107526,0.00032092253,0.00010075404,0.000335401,0.00007163334,0.00064193405,0.00018358704,0.0008924299],"category_scores_gemma":[0.00019415049,0.00017042426,0.00021423458,0.00021142868,0.00012783874,0.000009114179,0.00019803227,0.00037438195,0.000018719566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003171403,0.00005208494,0.000011810345,0.000008603627,0.00021997286,0.000075197604,0.000011116719,0.000122069694,0.6685154,0.000038535058,0.3177827,0.0128453635],"study_design_scores_gemma":[0.0012928786,0.00031460027,0.000014153482,0.000034180004,0.000072266135,0.00021140458,0.00007084553,0.000046225658,0.5572733,0.00007240714,0.44049007,0.00010765515],"about_ca_topic_score_codex":0.000027559752,"about_ca_topic_score_gemma":0.000023940169,"teacher_disagreement_score":0.12270737,"about_ca_system_score_codex":0.00005956046,"about_ca_system_score_gemma":0.00041041328,"threshold_uncertainty_score":0.9771482},"labels":[],"label_agreement":null},{"id":"W7117558201","doi":"10.1021/acsptsci.5c00726","title":"Deciphering Opioid Peptide Binding Modes at Atypical Chemokine Receptor 3","year":2025,"lang":"en","type":"article","venue":"ACS Pharmacology & Translational Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Fonds National de la Recherche Luxembourg; Deutsche Forschungsgemeinschaft; European Cooperation in Science and Technology; Joachim Herz Stiftung","keywords":"Dynorphin; Nociceptin receptor; Pharmacophore; Ligand (biochemistry); Opioid receptor; Internalization; G protein-coupled receptor; Receptor","score_opus":0.01113572206533058,"score_gpt":0.2973773950853763,"score_spread":0.2862416730200457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117558201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9878372,0.00034203482,0.008773725,0.0006469448,0.00057207915,0.00016743394,0.000013343023,0.000021152451,0.0016261039],"genre_scores_gemma":[0.9930948,0.00010496545,0.004829321,0.0006275361,0.00020035927,0.000029824067,0.000048387472,0.0000094437055,0.0010553551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9986555,0.000033442266,0.00021845402,0.0004966194,0.00023047932,0.00036551774],"domain_scores_gemma":[0.99958396,0.000038675378,0.000048670125,0.00011993356,0.00010673174,0.00010201823],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042666803,0.00014388456,0.00012546625,0.000091535534,0.00046561004,0.000028114287,0.00039432387,0.000112507114,0.00060424797],"category_scores_gemma":[0.00002982767,0.00014149632,0.000068079855,0.0003636238,0.00032835518,0.00001919451,0.00012979541,0.00011471612,0.000024411434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013824423,0.00003077167,0.0015145066,0.00000714232,0.000027358074,8.4551783e-7,0.00003654924,0.0012150884,0.9935596,0.00085444807,0.0010395128,0.001575919],"study_design_scores_gemma":[0.000547973,0.000042543536,0.0012340791,0.0000110225055,0.000020402806,0.0000046284763,0.000016370364,0.001184783,0.9744887,0.0002456357,0.022057587,0.00014631511],"about_ca_topic_score_codex":0.000003359849,"about_ca_topic_score_gemma":0.000005471296,"teacher_disagreement_score":0.021018075,"about_ca_system_score_codex":0.000055877004,"about_ca_system_score_gemma":0.00025188748,"threshold_uncertainty_score":0.6616092},"labels":[],"label_agreement":null},{"id":"W7117647749","doi":"10.1016/j.apsb.2025.12.043","title":"A neurotensin receptor type 1-derived pepducin acts as a biased allosteric modulator to regulate target receptor function","year":2025,"lang":"en","type":"article","venue":"Acta Pharmaceutica Sinica B","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Institute of Neurosciences, Mental Health and Addiction; Région Normandie; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; European Commission","keywords":"Allosteric regulation; Neurotensin receptor; Neurotensin; G protein-coupled receptor; Allosteric modulator; Agonist; Receptor; Function (biology); Intracellular","score_opus":0.022306956343136602,"score_gpt":0.3105612511352747,"score_spread":0.2882542947921381,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7117647749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98810846,0.0004137685,0.0009840628,0.005757814,0.002543512,0.0008561356,0.000030448842,0.00010499868,0.0012008244],"genre_scores_gemma":[0.98301005,0.0002735091,0.0038199387,0.008755116,0.00040619448,0.00004926381,0.00021599593,0.00007657729,0.0033933776],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99743223,0.00026028993,0.00049855,0.0009560696,0.00026163293,0.00059123413],"domain_scores_gemma":[0.9984074,0.000055824745,0.00014797431,0.00073050655,0.00029014793,0.00036811086],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00040517055,0.00039753361,0.0003863163,0.00016073276,0.00020228514,0.00009962676,0.0003994104,0.0003031437,0.001293543],"category_scores_gemma":[0.00054531224,0.00039957042,0.0001869269,0.00058085046,0.00006264792,0.000018410561,0.00030658187,0.00027438885,0.00029993098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018928961,0.00012456144,0.000034611687,0.000026427271,0.00018128379,0.0000027957544,0.0000457335,0.000087594075,0.96210724,0.00005772586,0.03333714,0.0021020037],"study_design_scores_gemma":[0.0007200285,0.00046953204,0.00012816442,0.00003955227,0.00005572238,0.000003755761,0.000029301773,0.00025505945,0.5676698,0.00004236148,0.4303217,0.00026501584],"about_ca_topic_score_codex":0.0000115828625,"about_ca_topic_score_gemma":0.0000020667119,"teacher_disagreement_score":0.39698458,"about_ca_system_score_codex":0.000052732277,"about_ca_system_score_gemma":0.00027652326,"threshold_uncertainty_score":0.9998456},"labels":[],"label_agreement":null},{"id":"W7132869033","doi":"","title":"Sites and roles of arrestin phosphorylation in regulating interactions between arrestin and rhodopsin of squid eyes","year":2008,"lang":"","type":"dissertation","venue":"TSpace","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Library and Archives Canada","funders":"","keywords":"Arrestin; Rhodopsin; Phosphorylation; Visual phototransduction; Phospholipase C; Depolarization; Kinase","score_opus":0.021114587730243602,"score_gpt":0.31733628505961,"score_spread":0.2962216973293664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132869033","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99176383,0.0068436405,0.00064175465,0.000033916775,0.00012525162,0.00029811476,0.000022850936,0.0000051351676,0.0002655318],"genre_scores_gemma":[0.9931102,0.0018613364,0.003733654,0.0000038559647,0.00012579012,0.000011346642,0.00062958425,0.000039756906,0.0004845212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99813503,0.00014470865,0.00076251756,0.0005339532,0.00018793101,0.00023587926],"domain_scores_gemma":[0.9984838,0.00016997692,0.0008361153,0.00023110984,0.00019257754,0.00008646205],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003050528,0.0003466325,0.00059687893,0.00020210494,0.00011223995,0.00002284366,0.00010700079,0.00039366484,0.000045474513],"category_scores_gemma":[0.00037728806,0.0003860791,0.00009472227,0.0001857662,0.00013918057,0.000013419714,0.00007305407,0.00024472247,3.777595e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021114305,0.000044972243,0.035221588,0.00031977805,0.00006692221,0.0000012281553,0.005299969,0.00034618328,0.94959754,0.000035924193,0.000013853372,0.008840876],"study_design_scores_gemma":[0.0005654019,0.00031353874,0.032115027,0.0009264074,0.00009189082,0.0000073235387,0.0072938735,0.0011688304,0.9569442,0.000109802415,0.00012212877,0.00034156823],"about_ca_topic_score_codex":0.000391383,"about_ca_topic_score_gemma":0.00050086936,"teacher_disagreement_score":0.008499308,"about_ca_system_score_codex":0.000017354138,"about_ca_system_score_gemma":0.00010529015,"threshold_uncertainty_score":0.9998591},"labels":[],"label_agreement":null},{"id":"W7132943989","doi":"","title":"Modelling the Effects of β-arrestin-Mediated Signaling in Cortical D2R Expressing Neurons using CRISPR-Cas9","year":2023,"lang":"","type":"dissertation","venue":"TSpace","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Dopamine; Signal transduction; Affect (linguistics); Schizophrenia (object-oriented programming); Dopamine receptor D2; Functional selectivity","score_opus":0.02802549391152688,"score_gpt":0.32028944253842323,"score_spread":0.29226394862689636,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7132943989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9586046,0.0036214516,0.034991793,0.000027347056,0.0018527512,0.00080455595,0.000008395541,0.000027439297,0.00006171283],"genre_scores_gemma":[0.9961156,0.0008914805,0.0015606544,0.00004154645,0.00037829654,0.000046668327,0.0003421274,0.00020094347,0.00042267446],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995877,0.00063259254,0.0010485909,0.0010140053,0.0005564753,0.00087132026],"domain_scores_gemma":[0.9973153,0.0008860465,0.0007221284,0.0006331357,0.00025750572,0.00018590673],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007413436,0.00069548486,0.0008059332,0.0002376935,0.0004055395,0.00011688483,0.00053262105,0.0008789156,0.00005795458],"category_scores_gemma":[0.0011876553,0.00063127733,0.0003732881,0.0005817696,0.00014421732,0.000011228616,0.00018147528,0.0010290241,0.000009466265],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018428061,0.00007438242,0.000054869004,0.0006455099,0.00008483546,0.00004278156,0.0039623138,0.23862308,0.7560339,0.000016455799,0.000014428341,0.00026314417],"study_design_scores_gemma":[0.00056811294,0.00021397666,0.000023055838,0.0016163241,0.00020291055,0.0000055232654,0.0055881096,0.33881178,0.65241265,0.000047099722,0.000043744534,0.0004666912],"about_ca_topic_score_codex":0.00091166777,"about_ca_topic_score_gemma":0.00004269841,"teacher_disagreement_score":0.103621244,"about_ca_system_score_codex":0.000055364377,"about_ca_system_score_gemma":0.00042546043,"threshold_uncertainty_score":0.9996139},"labels":[],"label_agreement":null},{"id":"W7133023578","doi":"","title":"Functional Properties of Monomers and Oligomers ofthe M2 Muscarinic Receptor","year":2014,"lang":"","type":"dissertation","venue":"TSpace","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Allosteric regulation; Cooperativity; G protein-coupled receptor; Receptor; Cooperative binding; Binding site; Monomer; G protein","score_opus":0.019021105453464113,"score_gpt":0.2575938732074195,"score_spread":0.2385727677539554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133023578","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9877568,0.007828083,0.000659658,0.00011708093,0.0013233416,0.00041516832,0.000012220981,0.000010595136,0.0018770781],"genre_scores_gemma":[0.98031074,0.003370658,0.00038727242,0.00006965581,0.00041062396,0.000050958537,0.00058762316,0.00008228338,0.014730188],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99782246,0.00013932884,0.0005591187,0.0007825317,0.0003052317,0.00039133456],"domain_scores_gemma":[0.9985472,0.00001873954,0.00055036,0.00041611525,0.00029092198,0.00017669477],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00036654054,0.00051301613,0.00059662864,0.0001333524,0.00017666705,0.00004583768,0.00021801406,0.0007159624,0.000820107],"category_scores_gemma":[0.00010028478,0.00048100576,0.00027699102,0.00011769843,0.00018227819,0.0000068859076,0.0000925105,0.00027309256,0.00002590178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005746937,0.00005755421,0.00007559756,0.0005120542,0.00032714376,2.3295662e-7,0.0020674975,0.000119202115,0.98966855,0.00014286306,0.00038757065,0.006067066],"study_design_scores_gemma":[0.00068987673,0.00064091414,0.0001993391,0.00029601902,0.0001617238,0.0000038158983,0.011030477,0.00017375432,0.96815413,0.00001886957,0.01805666,0.00057443994],"about_ca_topic_score_codex":0.00018801031,"about_ca_topic_score_gemma":0.000033324362,"teacher_disagreement_score":0.021514416,"about_ca_system_score_codex":0.00002775691,"about_ca_system_score_gemma":0.00024032374,"threshold_uncertainty_score":0.99976414},"labels":[],"label_agreement":null},{"id":"W7133044999","doi":"","title":"Amino acid-activated family C G-protein coupled receptors","year":2006,"lang":"","type":"dissertation","venue":"TSpace","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Toronto","keywords":"Amino acid; Allosteric regulation; Receptor; Metabotropic glutamate receptor; Metabotropic receptor; Ligand (biochemistry); Isoleucine; Peptide sequence","score_opus":0.012516415356289242,"score_gpt":0.27995040258937903,"score_spread":0.2674339872330898,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7133044999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.980548,0.005123772,0.0036486513,0.000068275964,0.0023675787,0.0012047762,0.000028392657,0.00006905271,0.0069415034],"genre_scores_gemma":[0.88489735,0.0007118862,0.0018904404,0.00012267841,0.001004358,0.0001816717,0.009042176,0.00027617058,0.10187326],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99552053,0.00024207788,0.00091658306,0.0016265782,0.0006442315,0.0010500242],"domain_scores_gemma":[0.99729735,0.000019427816,0.0008925453,0.00094737165,0.00052676065,0.00031657383],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003873169,0.0012018665,0.0009422761,0.00020463133,0.00045019024,0.00019837079,0.0006474975,0.0021131982,0.0016158454],"category_scores_gemma":[0.00013127849,0.0013027665,0.00058948435,0.00041790967,0.000110589,0.000011150578,0.00012126755,0.00073332293,0.000173371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059832627,0.0001779698,0.000013382856,0.00019348855,0.00027259378,0.000012943597,0.00054924376,0.000112798225,0.9924841,0.00007155845,0.0024106596,0.003102933],"study_design_scores_gemma":[0.0011101373,0.0007341812,0.0000815393,0.00031672567,0.00014305631,0.00000422308,0.004385651,0.00030548082,0.95132244,0.00004966446,0.040172037,0.0013748932],"about_ca_topic_score_codex":0.0011954905,"about_ca_topic_score_gemma":0.00013393632,"teacher_disagreement_score":0.09565064,"about_ca_system_score_codex":0.00013455517,"about_ca_system_score_gemma":0.00051760423,"threshold_uncertainty_score":0.9992968},"labels":[],"label_agreement":null},{"id":"W7162197060","doi":"10.82308/6382","title":"G protein-coupled receptor-mediated transcriptional regulation in pathological cardiac remodelling","year":2020,"lang":"en","type":"dissertation","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Heart failure; Pathological; Contractility; Cardiac function curve; Ventricle; Receptor; Disease; Signal transduction; Fibrosis","score_opus":0.012968271915417754,"score_gpt":0.22966582299440874,"score_spread":0.216697551078991,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7162197060","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9836661,0.001176207,0.0103402585,0.00009215515,0.0006811866,0.00094255887,0.00003291644,0.000051415103,0.003017189],"genre_scores_gemma":[0.9597554,0.00042320407,0.0059096217,0.00009194038,0.0005571339,0.00017330066,0.02701712,0.00007660531,0.0059956303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982133,0.000111820336,0.00046376642,0.00066977716,0.00028117216,0.00026019962],"domain_scores_gemma":[0.9994521,0.000009013332,0.00014331605,0.0001826152,0.00011828306,0.00009466768],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00026619312,0.00030878172,0.0003669615,0.00007900882,0.000060865514,0.000034012068,0.00015867039,0.0008231645,0.00058472727],"category_scores_gemma":[0.00007948809,0.0002943034,0.00023466808,0.00014579033,0.000015590109,0.0000050156605,0.000014114813,0.0003091039,0.0000370236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033949438,0.000030869287,0.000018214429,0.0000491101,0.000028581771,0.000002411323,0.00012049155,0.00021217382,0.99776345,0.00074635365,0.00012726984,0.00056160364],"study_design_scores_gemma":[0.00076997554,0.00036583695,0.0005240484,0.00016223385,0.000030610085,0.0000013093139,0.0005035264,0.0065261293,0.9762087,0.0007176846,0.013390468,0.0007994788],"about_ca_topic_score_codex":0.000020812606,"about_ca_topic_score_gemma":0.000032621017,"teacher_disagreement_score":0.026984204,"about_ca_system_score_codex":0.000031171054,"about_ca_system_score_gemma":0.00012894391,"threshold_uncertainty_score":0.9999509},"labels":[],"label_agreement":null},{"id":"W74426933","doi":"10.1182/blood.v95.3.894.003k15_894_902","title":"Platelet secretion induced by phorbol esters stimulation is mediated through phosphorylation of MARCKS: a MARCKS-derived peptide blocks MARCKS phosphorylation and serotonin release without affecting pleckstrin phosphorylation*","year":2000,"lang":"en","type":"article","venue":"Blood","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"MARCKS; Phosphorylation; Protein kinase C; Biology; Pleckstrin homology domain; Cell biology; Biochemistry","score_opus":0.008919457842009702,"score_gpt":0.2299009571910334,"score_spread":0.2209814993490237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W74426933","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99449897,0.0009545522,0.002684303,0.00007291997,0.00009361786,0.0011826605,0.00009316475,0.000067309644,0.0003524949],"genre_scores_gemma":[0.9950685,0.0006066267,0.002241081,0.00015201444,0.000118383825,0.00007946123,0.001357105,0.000085419946,0.0002913883],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973064,0.00018362766,0.00074763247,0.00083693373,0.00046538466,0.00046001014],"domain_scores_gemma":[0.99863505,0.00007016819,0.0004826382,0.00041527065,0.00022929652,0.00016758649],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00045401682,0.00046818572,0.00044915194,0.00009380388,0.0002573547,0.00007801684,0.00017610399,0.0005314434,0.0007496442],"category_scores_gemma":[0.00014051353,0.0005077414,0.00013487534,0.00035832942,0.000085994885,0.00006530095,0.000070735434,0.00027981002,0.000010367205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00065943564,0.00021090676,0.006891774,0.000059405855,0.00016965452,0.0000025182126,0.0010633589,0.00060293067,0.98273706,0.000006471306,0.00018033368,0.007416117],"study_design_scores_gemma":[0.0045135007,0.0006435971,0.00417625,0.00013856107,0.00014575946,0.00001705095,0.0003222302,0.005682018,0.98298836,0.00012815189,0.0006846675,0.00055986806],"about_ca_topic_score_codex":0.00034448455,"about_ca_topic_score_gemma":0.000025683046,"teacher_disagreement_score":0.0068562487,"about_ca_system_score_codex":0.000049947495,"about_ca_system_score_gemma":0.000107772335,"threshold_uncertainty_score":0.99973744},"labels":[],"label_agreement":null},{"id":"W744522243","doi":"10.71781/4774","title":"Implication des interactions médicamenteuses, des transporteurs membranaires, du sexe et du diabète dans les mécanismes de survenue du syndrome du QT long médicamenteux","year":2008,"lang":"fr","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine","score_opus":0.007199791989489639,"score_gpt":0.18961877103505295,"score_spread":0.1824189790455633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W744522243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96471345,0.014783453,0.016543727,0.000367886,0.0007493442,0.0004442091,0.00027719577,0.00007150483,0.0020492226],"genre_scores_gemma":[0.973776,0.017958187,0.0011087456,0.00009238565,0.00028392812,0.00008134439,0.0030583704,0.00008321177,0.003557849],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9970185,0.00038646502,0.0006152901,0.00089001306,0.00046828052,0.00062142446],"domain_scores_gemma":[0.9980872,0.00008896816,0.000541138,0.0004300937,0.00039792465,0.0004546601],"candidate_categories":["metaepi_narrow","sts"],"consensus_categories":[],"category_scores_codex":[0.0003596704,0.00065163843,0.00050368026,0.00023265858,0.006961283,0.000100528625,0.0005591953,0.0005838539,0.000081297665],"category_scores_gemma":[0.00009671047,0.0007865578,0.0005719066,0.0002536106,0.00066710374,0.0001196507,0.00012082248,0.00044677433,0.000012275429],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00073802535,0.00083354494,0.23166682,0.0003625571,0.0012598159,0.0031669454,0.024403792,0.0059928256,0.71905285,0.007754208,0.00043056114,0.0043380484],"study_design_scores_gemma":[0.0025718072,0.00071438344,0.52976346,0.0011566975,0.0011945389,0.016576232,0.03321141,0.0015683887,0.3623311,0.00034926573,0.048749603,0.0018130955],"about_ca_topic_score_codex":0.045217853,"about_ca_topic_score_gemma":0.031826947,"teacher_disagreement_score":0.35672176,"about_ca_system_score_codex":0.0029817512,"about_ca_system_score_gemma":0.0017014337,"threshold_uncertainty_score":0.99945855},"labels":[],"label_agreement":null},{"id":"W760715003","doi":"10.1016/j.bcp.2015.06.019","title":"From B.Sc. to Ph.D., my shuffle off to Buffalo","year":2015,"lang":"en","type":"review","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Nucro Technics","funders":"","keywords":"Muscarinic acetylcholine receptor; Tachyphylaxis; Chemistry; Contraction (grammar); Depolarization; Neuroscience; Pharmacology; Medicine; Receptor; Internal medicine; Biology; Biochemistry","score_opus":0.04395937114015567,"score_gpt":0.3743621040463773,"score_spread":0.33040273290622163,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W760715003","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.002176457,0.9930778,0.00032468291,0.00016917645,0.0021199498,0.0011462446,0.00039767494,0.000047123343,0.0005408928],"genre_scores_gemma":[0.00030713092,0.9846631,0.0022971302,0.002501346,0.006480571,0.0005008559,0.0018316634,0.00017096108,0.0012471917],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99673843,0.00022071846,0.0007032394,0.0013391444,0.00027220254,0.00072623923],"domain_scores_gemma":[0.9980788,0.000051165433,0.00019417911,0.00056263286,0.0001790361,0.0009341741],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00032041513,0.0007019365,0.0014702865,0.00014464515,0.000062216735,0.000037197264,0.000988742,0.00109685,0.0012035724],"category_scores_gemma":[0.00012242635,0.00063928874,0.0005034384,0.0002891036,0.00006300474,0.0000028677107,0.0008512028,0.00041252974,0.001031777],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055458662,0.00006711444,7.008295e-8,0.00019314434,0.00019088548,0.0000092693945,0.000019441879,0.0000016269713,0.33219597,0.0000031081804,0.5370836,0.13018031],"study_design_scores_gemma":[0.00030706072,0.00026054095,4.832735e-8,0.000270474,0.0003738532,0.0000120919285,0.000008850596,0.000001449504,0.19620778,0.000030482795,0.80192626,0.00060109684],"about_ca_topic_score_codex":0.000043697735,"about_ca_topic_score_gemma":0.0000012703365,"teacher_disagreement_score":0.26484266,"about_ca_system_score_codex":0.00013647514,"about_ca_system_score_gemma":0.00044800638,"threshold_uncertainty_score":0.999746},"labels":[],"label_agreement":null},{"id":"W77380462","doi":"10.1007/978-0-387-26575-9_72","title":"The Structural Determinants of GPCR Binding and Activation: Insights from Mutagenesis and Molecular Modeling Studies of the Human Angiotensin II Type 1 (hAT1) Receptor","year":2010,"lang":"en","type":"book-chapter","venue":"","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Mutagenesis; Angiotensin II; Computational biology; Receptor; Genetics; Chemistry; Biology; Mutation; Gene","score_opus":0.02448202600998421,"score_gpt":0.26155625121034043,"score_spread":0.23707422520035623,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W77380462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99464077,0.004495073,0.00006240575,0.000025822215,0.0002358857,0.00018657824,0.00001798015,0.0000036885885,0.00033178512],"genre_scores_gemma":[0.9943996,0.0009300771,0.0009395654,0.000027839602,0.00011542597,0.0000019976292,0.000026627557,0.000035286954,0.0035235623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99905664,0.000025801388,0.00033154755,0.0003156071,0.00015818859,0.00011224487],"domain_scores_gemma":[0.9990932,0.00002774433,0.00028766328,0.00033523975,0.0002232075,0.000032979195],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008597759,0.00023988858,0.00031882233,0.000035297016,0.00038280434,0.000019082647,0.00016698871,0.0003346645,0.000021212105],"category_scores_gemma":[0.00003702261,0.00013890577,0.000099139885,0.000020181218,0.00020363335,0.0000048231013,0.00034707555,0.00014400664,1.5193503e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020273448,0.0000017728579,0.00003377342,0.00001604114,0.00017194828,3.5783455e-7,0.00016420714,0.000010432469,0.997315,0.001177424,0.000013610961,0.0010751458],"study_design_scores_gemma":[0.00015895168,0.000117425465,0.000018641977,0.00013493471,0.00008001096,0.000002337323,0.00018072934,0.00020259949,0.99435115,0.003594176,0.0009692983,0.00018973829],"about_ca_topic_score_codex":0.00004631498,"about_ca_topic_score_gemma":0.000073614,"teacher_disagreement_score":0.0035649962,"about_ca_system_score_codex":0.0000067493,"about_ca_system_score_gemma":0.000033077944,"threshold_uncertainty_score":0.56644136},"labels":[],"label_agreement":null},{"id":"W779999566","doi":"","title":"GPR81 (HCA1), a Novel Lactate Receptor, mediates the Development of Inner Vasculature in Mouse Retina","year":2015,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Hôpital Maisonneuve-Rosemont; McGill University","funders":"","keywords":"Retina; Cell biology; Receptor; Neuroscience; Chemistry; Biology; Medicine; Internal medicine","score_opus":0.04243565339220379,"score_gpt":0.310777744276583,"score_spread":0.2683420908843792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W779999566","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987554,0.00017077138,0.000056031808,0.00017262665,0.0002181251,0.00020973169,0.0000057638485,0.0000066882562,0.00040484226],"genre_scores_gemma":[0.9897694,0.00000530177,0.009790447,0.00011344243,0.000060689687,0.00003559229,0.000021173992,0.000014059695,0.00018988503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.998166,0.00014883508,0.00037747712,0.0005124035,0.00039087512,0.0004043794],"domain_scores_gemma":[0.9989879,0.000039534167,0.00019492612,0.0002457482,0.00032672385,0.00020517834],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019763347,0.00019691094,0.00021929688,0.0001000984,0.000149492,0.000025619136,0.00058721896,0.00017221893,0.000031294858],"category_scores_gemma":[0.00094321585,0.00013636256,0.000047845155,0.00057193084,0.0017751532,0.00002158401,0.00033499463,0.00020744989,0.000010119067],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033675253,0.000071287825,0.0048026564,0.0000054919196,0.000014664694,0.0000027440692,0.002401586,0.00009040084,0.9923147,0.00009302579,0.00004200391,0.00012776713],"study_design_scores_gemma":[0.00036885167,0.0002951177,0.0034798102,0.00002391995,0.0000036384758,0.000022614557,0.00091640616,0.00011948799,0.9935831,0.0006004733,0.00040511717,0.00018148067],"about_ca_topic_score_codex":0.000046474655,"about_ca_topic_score_gemma":0.000018074044,"teacher_disagreement_score":0.0097344145,"about_ca_system_score_codex":0.000055441913,"about_ca_system_score_gemma":0.00082418113,"threshold_uncertainty_score":0.65406257},"labels":[],"label_agreement":null},{"id":"W794565495","doi":"10.3791/52824","title":"Tracking Drug-induced Changes in Receptor Post-internalization Trafficking by Colocalizational Analysis","year":2015,"lang":"en","type":"article","venue":"Journal of Visualized Experiments","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Internalization; Colocalization; Intracellular; Receptor; Cell biology; Extracellular; Confocal microscopy; Biology; Chemistry; Biochemistry","score_opus":0.02852636616673982,"score_gpt":0.38007518067857116,"score_spread":0.35154881451183134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W794565495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9709237,0.0010358643,0.027396949,0.00007719569,0.00040504566,0.00010188922,0.0000074255736,0.000005436977,0.000046455876],"genre_scores_gemma":[0.9980482,0.00008856806,0.0011168144,0.00025792414,0.00022131132,0.000006541914,0.00013363232,0.00002456751,0.000102444035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984565,0.00019094937,0.00052707846,0.0002051964,0.000416858,0.00020341818],"domain_scores_gemma":[0.99886537,0.000011873916,0.00045220292,0.00010433458,0.0004109928,0.00015523011],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006362926,0.00016184282,0.00032548173,0.00028590098,0.000040149658,0.00006118436,0.00020079118,0.00011986348,0.0001434617],"category_scores_gemma":[0.0001275309,0.00015114731,0.00015536643,0.00033904478,0.000016327309,0.000020954465,0.000039594637,0.00009108921,0.0000020753703],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031635285,0.00019543072,0.0017011842,0.000003940418,0.00029016213,0.000004443045,0.0010696537,0.00070116436,0.9939957,0.000028708708,0.0011252505,0.00056795415],"study_design_scores_gemma":[0.0018821915,0.00044318134,0.00006255204,0.00004437845,0.00006748311,0.000009198824,0.0014253414,0.0009188437,0.99114203,0.000012042332,0.0038169655,0.00017576833],"about_ca_topic_score_codex":0.000033087552,"about_ca_topic_score_gemma":0.000033447504,"teacher_disagreement_score":0.027124459,"about_ca_system_score_codex":0.00009334121,"about_ca_system_score_gemma":0.00009732756,"threshold_uncertainty_score":0.61636084},"labels":[],"label_agreement":null},{"id":"W850168373","doi":"10.1096/fasebj.20.5.a1115-b","title":"Modeling Ca <sup>2+</sup> oscillations in vascular smooth muscle cells","year":2006,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"SERCA; Biophysics; Vascular smooth muscle; Endoplasmic reticulum; Chemistry; Calcium; Cytosol; Oscillation (cell signaling); Coupling (piping); Smooth muscle; Materials science; Biology; Biochemistry; ATPase; Endocrinology","score_opus":0.009773018613802337,"score_gpt":0.2133466400897496,"score_spread":0.20357362147594726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W850168373","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95361835,0.00068594405,0.044910837,0.00009075128,0.00010734119,0.00007826816,0.000006263975,0.000004959218,0.00049728504],"genre_scores_gemma":[0.9978402,0.00016704801,0.0011100085,0.00011322087,0.00058616593,0.0000031845457,0.000018011457,0.000018658064,0.00014346748],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99907225,0.00009552733,0.00025081102,0.0001552726,0.00017088148,0.0002552519],"domain_scores_gemma":[0.9996259,0.000008243634,0.0000522173,0.00019965065,0.000058385842,0.00005559328],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005041098,0.00011606874,0.00010628542,0.000052943313,0.00023001555,0.00006798882,0.00019475336,0.00008820363,0.00015067092],"category_scores_gemma":[0.0000137431525,0.00008534177,0.00013645682,0.000086299544,0.00002244972,0.0000062234394,0.00004448163,0.00020075095,0.000014012275],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004409054,0.000013906785,0.00002115565,0.0000011075376,0.0000070237334,0.000002737755,0.000058981168,0.49123427,0.508208,0.000030437983,0.00015941898,0.0002585404],"study_design_scores_gemma":[0.0010996858,0.00012324525,0.00014095726,0.000043573607,0.00004354413,0.000027605027,0.00091259636,0.6569157,0.32996917,0.002408004,0.0079454025,0.00037050774],"about_ca_topic_score_codex":0.000174273,"about_ca_topic_score_gemma":0.000036034304,"teacher_disagreement_score":0.17823882,"about_ca_system_score_codex":0.00002342892,"about_ca_system_score_gemma":0.000061670806,"threshold_uncertainty_score":0.34801364},"labels":[],"label_agreement":null},{"id":"W85943631","doi":"","title":"Contribució del receptor domini discoidina 1 (ddr1) en el procés de mielinització. Aplicació de diferents models experimentals","year":2010,"lang":"ca","type":"dissertation","venue":"TDX (Tesis Doctorals en Xarxa)","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Humanities; Art; Philosophy; Cartography; Geography","score_opus":0.014131637207475702,"score_gpt":0.3245840063186973,"score_spread":0.31045236911122165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W85943631","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9787013,0.0055934237,0.010034578,0.00017917728,0.001764047,0.001950065,0.00081010524,0.000103918785,0.0008634128],"genre_scores_gemma":[0.97233075,0.0029347003,0.0083826985,0.0003816312,0.0021063944,0.0009808788,0.0072368113,0.0003875026,0.0052586533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9925123,0.0009162869,0.0016907788,0.0021351026,0.0008199998,0.0019255502],"domain_scores_gemma":[0.9957806,0.00029971273,0.0010983497,0.001382329,0.00050184474,0.0009372042],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.001526133,0.0016616443,0.001691555,0.00027790063,0.0005625312,0.0003876887,0.0015329546,0.0035918371,0.0016654697],"category_scores_gemma":[0.00056978036,0.0016749483,0.0010598507,0.00026724456,0.00015032188,0.000069638125,0.0002985204,0.0013478997,0.0001416271],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010564125,0.0006625862,0.0007926679,0.00030458797,0.0006935546,0.000017315879,0.0026849622,0.00015015995,0.9879227,0.0006162748,0.001896169,0.0032025522],"study_design_scores_gemma":[0.0025482844,0.0006925909,0.0001701968,0.00046925948,0.00048486126,0.000029450992,0.002670432,0.001552843,0.9809588,0.0010145195,0.0074728653,0.0019359034],"about_ca_topic_score_codex":0.00041684855,"about_ca_topic_score_gemma":0.00010898634,"teacher_disagreement_score":0.0069639636,"about_ca_system_score_codex":0.00042562882,"about_ca_system_score_gemma":0.00090261153,"threshold_uncertainty_score":0.99961305},"labels":[],"label_agreement":null},{"id":"W869617475","doi":"10.1139/y05-158","title":"NPY, ET-1, and Ang II nuclear receptors in human endocardial endothelial cellsThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell.","year":2006,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; Centre Hospitalier Universitaire de Québec","keywords":"Receptor; Nucleus; Neuropeptide Y receptor; Cell biology; Biology; G protein-coupled receptor; Homeostasis; Endocrinology; Internal medicine; Neuropeptide; Biochemistry; Medicine","score_opus":0.009889874174331839,"score_gpt":0.2529915794736858,"score_spread":0.24310170529935393,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W869617475","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.42147002,0.5678922,0.0000011274835,0.0002241285,0.0031100975,0.0010432898,0.0002611268,0.0000034440034,0.00599458],"genre_scores_gemma":[0.21367604,0.7815812,0.00015331511,0.0006628881,0.0031109422,0.00001770527,0.00007014401,0.00007600183,0.00065177795],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979119,0.0006109599,0.00079402607,0.00030260856,0.00008321336,0.0002973201],"domain_scores_gemma":[0.9988628,0.000054615055,0.0007543888,0.00010335367,0.0000860296,0.00013880871],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00057961885,0.00026247956,0.0010174873,0.00033681083,0.00010943295,0.000013120774,0.00024483944,0.00049220043,0.024468545],"category_scores_gemma":[0.000019938607,0.00021348833,0.00024308315,0.00017876687,0.00026219914,0.00001557249,0.000057568817,0.0006297221,9.670016e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010212734,0.00008567907,0.00002422573,0.0009243577,0.00016420402,0.000008807402,0.00084776623,0.000014289921,0.98084694,0.000032720036,0.01318281,0.0037660727],"study_design_scores_gemma":[0.0011840311,0.0007110361,0.00001456064,0.00024509995,0.0002686721,0.000031535274,0.00008796359,0.0000026918983,0.15429775,0.00009828062,0.8428524,0.0002059546],"about_ca_topic_score_codex":0.0017560498,"about_ca_topic_score_gemma":0.0021268995,"teacher_disagreement_score":0.8296696,"about_ca_system_score_codex":0.0000492695,"about_ca_system_score_gemma":0.00063821935,"threshold_uncertainty_score":0.9764232},"labels":[],"label_agreement":null},{"id":"W872001886","doi":"10.1016/j.ymeth.2015.07.005","title":"Caged ligands to study the role of intracellular GPCRs","year":2015,"lang":"en","type":"article","venue":"Methods","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Institut National de la Recherche Scientifique; Armand Frappier Museum; Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Fondation Leducq; Heart and Stroke Foundation of Canada","keywords":"G protein-coupled receptor; Intracellular; Chemistry; Computational biology; Receptor; Cell biology; Biology; Biochemistry","score_opus":0.03486807526369279,"score_gpt":0.3510148254625026,"score_spread":0.31614675019880983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W872001886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.86698455,0.0009355514,0.13114004,0.000043279688,0.0001561422,0.00020359943,0.0000013511602,0.0000050942,0.000530404],"genre_scores_gemma":[0.9378881,0.000005702345,0.061652884,0.00007198601,0.00012352134,0.000019403884,0.0000031227594,0.00001261155,0.00022269448],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991684,0.0002795953,0.0001515091,0.00017009422,0.00010808352,0.00012233271],"domain_scores_gemma":[0.9994651,0.000019816756,0.00004508512,0.00031113575,0.00007783199,0.000080999875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020041803,0.00008217479,0.00012109289,0.00002012459,0.000040800125,0.000011629505,0.0002038175,0.00005636796,0.000027384149],"category_scores_gemma":[0.00021548831,0.00005572713,0.0000484765,0.00009186317,0.000015840475,0.0000010298736,0.000108188244,0.00005884875,0.000003497869],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003202346,0.00005329156,0.00039253006,8.9778547e-7,0.0000393363,5.846843e-7,0.00096615,0.00013168737,0.96395296,0.00005509905,0.0000834945,0.03429197],"study_design_scores_gemma":[0.00020628228,0.00051949546,0.00007423441,0.0000015143908,0.00001899548,0.0000017422801,0.0028942062,0.00009656124,0.97409266,0.0005775139,0.021444162,0.000072646806],"about_ca_topic_score_codex":0.000035412642,"about_ca_topic_score_gemma":0.000004470033,"teacher_disagreement_score":0.07090353,"about_ca_system_score_codex":0.000004581367,"about_ca_system_score_gemma":0.000030155608,"threshold_uncertainty_score":0.22724864},"labels":[],"label_agreement":null},{"id":"W900130332","doi":"10.1016/j.cellsig.2015.07.006","title":"Functional importance of two conserved residues in intracellular loop 1 and transmembrane region 2 of Family A GPCRs: Insights from ligand binding and signal transduction responses of D1 and D5 dopaminergic receptor mutants","year":2015,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"G protein-coupled receptor; Adenylyl cyclase; Receptor; Dopamine receptor D2; Transmembrane domain; Dopamine receptor; Signal transduction; cAMP-dependent pathway; Cell biology; Gs alpha subunit; Dopaminergic; Biology; Mutant; G protein; Chemistry; Biochemistry; Dopamine; Gene; Neuroscience","score_opus":0.031341181751974465,"score_gpt":0.2316544531406032,"score_spread":0.20031327138862876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W900130332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97090214,0.02043481,0.008320839,0.000020009611,0.00007479289,0.00020308112,0.000025976224,0.0000058536552,0.000012513398],"genre_scores_gemma":[0.99723434,0.0012369024,0.0012848083,0.000008969937,0.0000771225,0.0000061239784,0.00009379357,0.00002490919,0.000033010667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983841,0.00017972205,0.0006172195,0.0004375573,0.00021498554,0.00016638535],"domain_scores_gemma":[0.9992299,0.00008836259,0.00028548617,0.0001428898,0.0001438513,0.00010948814],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045497128,0.00021273652,0.0004261188,0.00016380381,0.000042796786,0.00001474155,0.00007771051,0.00019376553,0.000012115503],"category_scores_gemma":[0.000047362246,0.00020803172,0.000058447655,0.00015509469,0.00021720961,0.000024900248,0.000028257482,0.00012123321,1.2336345e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001252042,0.000057522724,0.0045507154,0.00012377715,0.00006695313,0.000017830547,0.00057169364,0.00035647358,0.99260044,0.00008131182,0.0000039250212,0.00031730067],"study_design_scores_gemma":[0.0021035096,0.00050097954,0.00038304421,0.0002866773,0.00005750766,0.000017211645,0.00092359865,0.0008618358,0.9941153,0.0005210757,0.000024353667,0.0002049133],"about_ca_topic_score_codex":0.000122575,"about_ca_topic_score_gemma":0.00003487827,"teacher_disagreement_score":0.026332235,"about_ca_system_score_codex":0.000010335309,"about_ca_system_score_gemma":0.000092223854,"threshold_uncertainty_score":0.8483287},"labels":[],"label_agreement":null},{"id":"W93536020","doi":"10.69645/ydzo9530","title":"Mechanism-based therapies for heart failure and cardiac arrhythmias","year":2007,"lang":"en","type":"article","venue":"The biomedical & life sciences collection.","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"","keywords":"Mechanism (biology); Heart failure; Cardiology; Medicine; Internal medicine; Physics","score_opus":0.01136679877768491,"score_gpt":0.2593117628530476,"score_spread":0.24794496407536268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W93536020","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.45808214,0.003016104,0.5283528,0.0072301268,0.002056481,0.00094838097,0.00003307665,0.000056258694,0.0002246446],"genre_scores_gemma":[0.98572826,0.000041012696,0.0114379125,0.0012812519,0.00082210824,0.000056070257,0.00001580471,0.0000130301205,0.00060455187],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9987213,0.000059882314,0.00020096902,0.00036888142,0.00031284217,0.00033614557],"domain_scores_gemma":[0.999429,0.00011549634,0.000059516606,0.00014261653,0.000075033546,0.00017837384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0016779265,0.00013067762,0.0001476618,0.00008482831,0.0008411746,0.00006216455,0.00017345998,0.00014974718,0.00005535879],"category_scores_gemma":[0.000103801685,0.000087489905,0.00011188149,0.0004237323,0.0004462853,0.000005767411,0.000044847326,0.00008174185,0.0000025117465],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013636102,0.000058377824,0.000326034,0.00002077341,0.00007468222,9.783546e-7,0.00017744172,0.000036763548,0.95468587,0.0023228738,0.03982865,0.0023311768],"study_design_scores_gemma":[0.0010076622,0.0019265234,0.00030466556,0.000022088754,0.00003777336,0.000020710704,0.0021481952,0.0025049588,0.2664216,0.003371677,0.7218301,0.0004040153],"about_ca_topic_score_codex":0.000025100346,"about_ca_topic_score_gemma":0.000041255676,"teacher_disagreement_score":0.6882643,"about_ca_system_score_codex":0.000013633871,"about_ca_system_score_gemma":0.00024078571,"threshold_uncertainty_score":0.64697206},"labels":[],"label_agreement":null},{"id":"W94953866","doi":"10.1096/fasebj.20.5.lb79-b","title":"Tonic plasma membrane association increases the function of RGS proteins as inhibitors of M1 muscarinic receptor signaling","year":2006,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"","keywords":"RGS2; Muscarinic acetylcholine receptor; Chemistry; Muscarinic acetylcholine receptor M1; Cell biology; Muscarinic acetylcholine receptor M3; Regulator of G protein signaling; Biophysics; Biochemistry; G protein; Receptor; Biology; GTPase-activating protein","score_opus":0.005875882293217744,"score_gpt":0.20287188961909156,"score_spread":0.1969960073258738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W94953866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979796,0.00046028942,0.00064896897,0.0001245844,0.0003082417,0.00018213342,0.000010711973,0.0000048633165,0.0002806235],"genre_scores_gemma":[0.99824345,0.000111334724,0.00016551916,0.00003858693,0.00095065316,0.0000075266103,0.000024362964,0.000015955828,0.00044260154],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987112,0.00023511033,0.00041861623,0.00012374956,0.00032633552,0.00018497225],"domain_scores_gemma":[0.9989157,0.000069654176,0.0006189227,0.00017019651,0.00018950248,0.000036047124],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011811672,0.00011941741,0.00015935226,0.000040511026,0.00020564254,0.000031555905,0.0002001918,0.00012599824,0.00019494913],"category_scores_gemma":[0.00015799752,0.00007242847,0.0001945786,0.00011126782,0.000046286415,0.000008855368,0.00004722604,0.00020332693,0.000004791602],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015391922,0.000055678003,0.00063385273,0.0000101204305,0.00009707842,3.7058015e-7,0.00004717054,0.0011840947,0.9965393,0.00012974661,0.0003650708,0.00078358647],"study_design_scores_gemma":[0.00044782352,0.000397732,0.0002626676,0.000048118167,0.00007467784,0.000018818431,0.00029334918,0.00005958806,0.9970341,0.00035254526,0.000925639,0.0000849404],"about_ca_topic_score_codex":0.00019498378,"about_ca_topic_score_gemma":0.000024636414,"teacher_disagreement_score":0.0011245066,"about_ca_system_score_codex":0.000039693226,"about_ca_system_score_gemma":0.00012315427,"threshold_uncertainty_score":0.29535475},"labels":[],"label_agreement":null},{"id":"W971580233","doi":"10.1016/j.bcp.2015.07.003","title":"The Triggle effect","year":2015,"lang":"en","type":"review","venue":"Biochemical Pharmacology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of British Columbia","funders":"","keywords":"Biopharmaceutical; Calcium channel; Pharmacology; Dihydropyridine; Engineering ethics; Chemistry; Calcium; Engineering; Medicine; Biology; Biotechnology","score_opus":0.03125057473576634,"score_gpt":0.376087645506922,"score_spread":0.34483707077115566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W971580233","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00012800645,0.9968648,0.0000290091,0.000027158118,0.0017190871,0.0007130438,0.000027462256,0.000023849096,0.0004676017],"genre_scores_gemma":[0.000040365,0.9958649,0.000050794748,0.00010396028,0.0020717506,0.0003088333,0.0003306047,0.000071522816,0.0011572295],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9978583,0.00046064315,0.00044872085,0.00057151803,0.000172653,0.00048820424],"domain_scores_gemma":[0.9989724,0.00014168568,0.00022431252,0.0003651532,0.0000786768,0.0002177691],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00075284607,0.00045048198,0.0008965282,0.000037990674,0.00014484531,0.000034895515,0.00070250966,0.00076662115,0.00012377885],"category_scores_gemma":[0.00010790808,0.00026930936,0.00056185824,0.00013191572,0.00016402024,0.0000011624459,0.0003235967,0.00040029752,0.00015389372],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054750853,0.000024899186,3.50404e-8,0.000667142,0.00026473316,0.0000051875813,0.0000015101499,1.2268464e-7,0.048477434,0.000013285576,0.63649106,0.31399983],"study_design_scores_gemma":[0.00035851327,0.00027100096,6.0122143e-9,0.00013060104,0.00047018455,0.000044613167,0.0000014091268,0.0000017294524,0.05140352,0.000021143433,0.9470004,0.00029688564],"about_ca_topic_score_codex":0.0000015795272,"about_ca_topic_score_gemma":8.314631e-8,"teacher_disagreement_score":0.31370294,"about_ca_system_score_codex":0.000060546314,"about_ca_system_score_gemma":0.000312298,"threshold_uncertainty_score":0.9999759},"labels":[],"label_agreement":null}]}