{"meta":{"query_hash":"2e680e25a51e","filters":{"topic":"Signaling Pathways in Disease"},"cohort_total":736,"direct_labels_cover":1,"predictions_cover":736,"exported":736,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/2e680e25a51e","api":"https://metacan.xera.ac/api/v1/cohort?topic=Signaling+Pathways+in+Disease"},"results":[{"id":"W105146300","doi":"10.1096/fasebj.21.6.a1207-a","title":"Assessment of the contribution of various Ca <sup>2+</sup> /Calcineurin‐regulated NFAT isoforms to the process of skeletal muscle fiber remodelling","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; Laurentian University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Chesapeake Research Consortium","keywords":"NFAT; Calcineurin; Gene isoform; Transcription factor; Phenotype; Cell biology; Skeletal muscle; Colocalization; Biology; Molecular biology; Chemistry; Internal medicine; Endocrinology; Biochemistry; Medicine; Gene","score_opus":0.00845252043645198,"score_gpt":0.26876486131608796,"score_spread":0.26031234087963595,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W105146300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955172,0.0010549176,0.0025099085,0.000024818595,0.000007917075,0.000028330485,0.00024689946,0.00002261682,0.00058735535],"genre_scores_gemma":[0.9900002,0.0011762418,0.0059863743,0.00003775004,0.000012369035,0.00008478415,0.00061987014,0.000025325115,0.0020570923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982953,0.000023075534,0.000020669986,0.000044540382,0.000039537586,0.000042609816],"domain_scores_gemma":[0.9998223,0.00003200668,0.000043735265,0.000022011865,0.000031118238,0.000048857168],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034949172,0.00039901564,0.00018380262,0.00037509872,0.00019266036,0.00034085102,0.00020388368,0.00032621334,0.0010220313],"category_scores_gemma":[0.00017845123,0.00018132143,0.00018809653,0.00019973598,0.0003476128,0.00032190146,0.00015677324,0.00038146714,0.000231221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014368817,0.000009054545,0.00049282593,0.000012697069,0.000001877768,0.000013059913,0.000009086699,0.000014124675,0.9989268,0.000018550854,0.0000026836367,0.00035547378],"study_design_scores_gemma":[0.000018774992,0.00043162887,0.033039026,0.0000057669376,0.000026834523,0.0003241636,0.00006035494,0.00062805077,0.964727,0.0000790098,0.0006541294,0.0000052426853],"about_ca_topic_score_codex":0.0007203182,"about_ca_topic_score_gemma":0.0011713476,"teacher_disagreement_score":0.0010220313,"about_ca_system_score_codex":0.00022266949,"about_ca_system_score_gemma":0.00016932371,"threshold_uncertainty_score":0.0034190416},"labels":[],"label_agreement":null},{"id":"W105356510","doi":"10.1096/fasebj.24.1_supplement.lb595","title":"Altered calcineurin‐NFAT signaling in the hearts of NFATc2 null mice","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"NFAT; Calcineurin; Transcription factor; Gene isoform; Cell biology; Biology; Molecular biology; Genetics; Internal medicine; Gene; Medicine; Transplantation","score_opus":0.014762107107802555,"score_gpt":0.2611933365563013,"score_spread":0.2464312294484987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W105356510","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99116313,0.00084987143,0.004218835,0.00029383603,0.0000959324,0.000039459024,0.0016851224,0.00032050713,0.001333262],"genre_scores_gemma":[0.9679919,0.0012899652,0.007970102,0.00026851473,0.00008554751,0.0002479484,0.0027704444,0.0006083003,0.018767362],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996238,0.000041766074,0.000051866715,0.00014248834,0.000092008704,0.000048095844],"domain_scores_gemma":[0.99922276,0.00008420301,0.00029458184,0.0000652963,0.000051402127,0.00028168125],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034116916,0.0012998818,0.0005325406,0.001509834,0.00042454165,0.00066118053,0.0006107865,0.0010306102,0.005157494],"category_scores_gemma":[0.00027841853,0.0006636006,0.00047101942,0.0003091655,0.00086814066,0.000602894,0.00039047244,0.0014893529,0.0010545986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019617606,0.00004206081,0.00019966636,0.000024185485,0.000007112025,0.00014188988,0.000032108313,0.000025861043,0.9986563,0.00011889706,0.000031372572,0.00052439485],"study_design_scores_gemma":[0.0005041668,0.0010369188,0.040207487,0.000073999916,0.00015601775,0.005554842,0.0002603801,0.0017327472,0.9438829,0.00080479,0.005727841,0.000057888545],"about_ca_topic_score_codex":0.0008126523,"about_ca_topic_score_gemma":0.0010876076,"teacher_disagreement_score":0.005157494,"about_ca_system_score_codex":0.00045279792,"about_ca_system_score_gemma":0.00027858684,"threshold_uncertainty_score":0.017253578},"labels":[],"label_agreement":null},{"id":"W14783732","doi":"10.1139/o11-045","title":"The roles of peptidyl-proline isomerases in gene regulation<sup>1</sup>This review is part of Special Issue entitled Asilomar Chromatin and has undergone the Journal’s usual peer review process.","year":2012,"lang":"en","type":"review","venue":"Biochemistry and Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chromatin; Biology; Gene; Function (biology); Isomerase; Posttranslational modification; Enzyme; Cell biology; Biochemistry; Chromatin remodeling; Phosphorylation; Computational biology","score_opus":0.03296288582915695,"score_gpt":0.301953892136129,"score_spread":0.26899100630697204,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W14783732","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000120527,0.99653,0.00027858798,0.0005103072,0.0010002898,0.0000044972176,0.00001761637,0.000009913236,0.001528309],"genre_scores_gemma":[0.0010283571,0.99603903,0.0002611966,0.0002647467,0.00082835706,0.00000590587,0.000041461724,0.0000033268898,0.0015274954],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99982834,0.00002701054,0.000024286395,0.000033583852,0.00006361091,0.000023132088],"domain_scores_gemma":[0.99960023,0.00014511163,0.000050108312,0.000017572618,0.00013180522,0.000055104272],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00059674215,0.0005759652,0.00084724795,0.0011130976,0.0003137298,0.0010197272,0.00070702017,0.0008557364,0.004185524],"category_scores_gemma":[0.0006349694,0.00021705133,0.00024120105,0.0015617462,0.00068318134,0.001382272,0.00077353494,0.0014476576,0.0033767202],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006065744,0.000022713462,0.00015266886,0.0065781213,0.00003815095,0.00014492826,0.00006153744,0.00018703258,0.003715811,0.00539859,0.04047111,0.9431689],"study_design_scores_gemma":[0.000004378605,0.00003261889,0.00048094973,0.0005765318,0.000024049505,0.0006239701,0.000037505175,0.000032208536,0.0007493274,0.001155427,0.99627423,0.0000086902155],"about_ca_topic_score_codex":0.0004111647,"about_ca_topic_score_gemma":0.00075678655,"teacher_disagreement_score":0.004185524,"about_ca_system_score_codex":0.000539673,"about_ca_system_score_gemma":0.00088885834,"threshold_uncertainty_score":0.0140019655},"labels":[],"label_agreement":null},{"id":"W1495703717","doi":"10.1074/jbc.m010298200","title":"Mechanism of Cyclosporin-induced Inhibition of Intracellular Collagen Degradation","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canadian Institutes of Health Research","funders":"","keywords":"Intracellular; Mechanism (biology); Chemistry; Degradation (telecommunications); Biophysics; Pharmacology; Cell biology; Biochemistry; Medicine; Biology; Computer science; Physics","score_opus":0.025510351349867517,"score_gpt":0.250317416174132,"score_spread":0.2248070648242645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1495703717","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9604036,0.020971585,0.010882797,0.00043348823,0.00014700009,0.00015034566,0.0010325467,0.000372077,0.0056065028],"genre_scores_gemma":[0.9923193,0.0034004292,0.0016604048,0.00007597875,0.000034856737,0.00007705309,0.00036355102,0.000021006,0.0020473336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997497,0.00005554095,0.000026026828,0.000035617806,0.00006514168,0.000067975016],"domain_scores_gemma":[0.99976486,0.000054877124,0.00006307475,0.000035688325,0.00003731112,0.00004426459],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002667458,0.00040449903,0.00035509773,0.0002884579,0.00023409698,0.00043263787,0.00019664354,0.00030149694,0.0011331842],"category_scores_gemma":[0.00020319647,0.00012565199,0.00038742277,0.00018311254,0.00026821624,0.00016792938,0.00018784362,0.0006356221,0.00037051443],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022716745,0.000041838888,0.0003359764,0.0001131621,0.000014205481,0.00015275784,0.000020817894,0.00010061995,0.9946128,0.00038481737,0.00010111198,0.0038947233],"study_design_scores_gemma":[0.00005064961,0.000345543,0.008479415,0.000011076368,0.000023216608,0.0005249551,0.000019161074,0.0008884584,0.9866905,0.00008180137,0.0028806224,0.0000046201753],"about_ca_topic_score_codex":0.000730393,"about_ca_topic_score_gemma":0.00072508724,"teacher_disagreement_score":0.0011331842,"about_ca_system_score_codex":0.00049751333,"about_ca_system_score_gemma":0.00030588155,"threshold_uncertainty_score":0.0037908554},"labels":[],"label_agreement":null},{"id":"W1496816974","doi":"10.1111/j.1556-4029.2012.02172.x","title":"Recognition of Early Myocardial Infarction by Immunohistochemical Staining with Cardiac Troponin‐I and Complement C9*","year":2012,"lang":"en","type":"article","venue":"Journal of Forensic Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Windsor Regional Hospital; University of Windsor","funders":"","keywords":"Myocardial infarction; Immunohistochemistry; Troponin; Medicine; Cardiology; Internal medicine; Troponin I; Complement (music); Forensic pathology; Pathology; Autopsy; Biology; Biochemistry","score_opus":0.01955083313533995,"score_gpt":0.26966466058252553,"score_spread":0.2501138274471856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1496816974","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.980736,0.0032266837,0.010787652,0.00018467565,0.000069266585,0.000112387555,0.00012737377,0.000057743517,0.0046983063],"genre_scores_gemma":[0.9822841,0.002334797,0.012801622,0.0000909651,0.00005620141,0.00004647456,0.00016372047,0.000008073943,0.0022140131],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99993145,0.000012335973,0.000010189605,0.000013086419,0.000012998481,0.000020029966],"domain_scores_gemma":[0.99979573,0.000041274143,0.000063200445,0.000017169596,0.000041097122,0.00004156376],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028938867,0.00018910824,0.0001428392,0.0004942052,0.0001659329,0.00020242357,0.00019080336,0.00043082028,0.0018190847],"category_scores_gemma":[0.00020981366,0.00009883724,0.00010681369,0.00017311625,0.00026079963,0.00026055385,0.0001789324,0.00030573286,0.00034854995],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031275724,0.00009602712,0.012369973,0.00007857742,0.000008927196,0.0008701383,0.000049647613,0.000024196313,0.98093367,0.00017214013,0.00006741581,0.005016544],"study_design_scores_gemma":[0.000038897393,0.0023270773,0.28294775,0.00007515795,0.00008878799,0.01036287,0.000722149,0.0019240922,0.6953641,0.00080319314,0.005319053,0.000026924892],"about_ca_topic_score_codex":0.00041587558,"about_ca_topic_score_gemma":0.00092312036,"teacher_disagreement_score":0.0018190847,"about_ca_system_score_codex":0.00009816304,"about_ca_system_score_gemma":0.000108550215,"threshold_uncertainty_score":0.006085396},"labels":[],"label_agreement":null},{"id":"W1509395137","doi":"10.4049/jimmunol.188.supp.68.1","title":"Cyclophilin A restricts rotavirus infection by enhancing type 1 interferon response in infected epithelial cells (68.1)","year":2012,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Cypa; Cyclophilin A; Downregulation and upregulation; Rotavirus; Biology; Interferon; Virology; Diarrhea; Viral replication; Immunology; Virus; Molecular biology; Medicine; Gene; Internal medicine","score_opus":0.009937968937258436,"score_gpt":0.25294174561366545,"score_spread":0.24300377667640702,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1509395137","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960104,0.0010360099,0.00086109265,0.00007308583,0.000026890031,0.000015902837,0.00048703866,0.00004580089,0.0014438153],"genre_scores_gemma":[0.9958646,0.0005995948,0.0010262274,0.000046880745,0.000020757961,0.000023805294,0.0008158474,0.000012123842,0.0015901193],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989057,0.00003158386,0.000009313494,0.00001734754,0.0000187766,0.00003231953],"domain_scores_gemma":[0.9999455,0.000013281118,0.000011174836,0.000009905049,0.0000057588113,0.000014377936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009528898,0.00018661894,0.0001734257,0.00018115535,0.00010466557,0.00024293063,0.000086361106,0.00014495579,0.0015793992],"category_scores_gemma":[0.00007808921,0.00008005326,0.00019950644,0.000105573636,0.00011137554,0.00007260258,0.0001440446,0.0002610076,0.00051146065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042873526,0.000009628744,0.00008122072,0.000010236488,0.0000013200635,0.00001089306,0.0000021015803,0.000008497086,0.99956495,0.000016400678,0.000024684517,0.00022722158],"study_design_scores_gemma":[0.00002132091,0.000343152,0.014189473,0.0000058338396,0.0000129611335,0.00018349431,0.000025570895,0.0008971188,0.9813945,0.000028995742,0.0028942896,0.0000033612034],"about_ca_topic_score_codex":0.00034971634,"about_ca_topic_score_gemma":0.00057972333,"teacher_disagreement_score":0.0015793992,"about_ca_system_score_codex":0.00017118474,"about_ca_system_score_gemma":0.00009479776,"threshold_uncertainty_score":0.0052836537},"labels":[],"label_agreement":null},{"id":"W1509956998","doi":"10.1046/j.1471-4159.2002.01122.x","title":"Inhibition of lipopolysaccharide‐induced cyclooxygenase‐2, tumor necrosis factor‐α and [Ca<sup>2+</sup>]<sub>i</sub> responses in human microglia by the peripheral benzodiazepine receptor ligand PK11195","year":2002,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":83,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Heart and Stroke Foundation of British Columbia and Yukon; Heart and Stroke Foundation of Canada","keywords":"Microglia; Tumor necrosis factor alpha; Lipopolysaccharide; Cyclooxygenase; Chemistry; Agonist; Cytokine; Receptor; Pharmacology; Intracellular; MPTP; Endocrinology; Internal medicine; Inflammation; Biology; Biochemistry; Medicine; Enzyme","score_opus":0.014682693854475735,"score_gpt":0.23723120130034708,"score_spread":0.22254850744587135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1509956998","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9890871,0.007156642,0.0012411716,0.00015620336,0.000043983946,0.00007141294,0.00038037394,0.00009035625,0.0017727399],"genre_scores_gemma":[0.9927141,0.0029853191,0.0019343096,0.00007017196,0.00002757219,0.00016877407,0.00060586294,0.000011424819,0.0014824538],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987245,0.000026978934,0.00001475484,0.00001313184,0.000023724735,0.000048909547],"domain_scores_gemma":[0.9999356,0.000009370059,0.000020308875,0.000009530569,0.000009096873,0.000016142527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015691995,0.00040613962,0.00027034277,0.000112560025,0.00012258455,0.00022634178,0.00015719101,0.00019429871,0.0008899545],"category_scores_gemma":[0.00016225083,0.00013536967,0.0002346854,0.0001206325,0.00020304715,0.0001348996,0.00017160132,0.00037472238,0.0004189085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008044875,0.000055968692,0.00009564387,0.000091922026,0.000010212477,0.000101937025,0.000024469084,0.000056421595,0.9968418,0.00005692999,0.00006384192,0.0017963386],"study_design_scores_gemma":[0.00021465664,0.0016106312,0.004628673,0.000017129014,0.000027372243,0.00060404325,0.000034609813,0.0006521306,0.98986316,0.00007914117,0.0022613578,0.000007109031],"about_ca_topic_score_codex":0.0005558297,"about_ca_topic_score_gemma":0.00091269804,"teacher_disagreement_score":0.0008899545,"about_ca_system_score_codex":0.00021433995,"about_ca_system_score_gemma":0.00025899423,"threshold_uncertainty_score":0.0029771924},"labels":[],"label_agreement":null},{"id":"W1516557136","doi":"10.1111/j.1742-4658.2008.06381.x","title":"The crystal structure of human WD40 repeat‐containing peptidylprolyl isomerase (PPWD1)","year":2008,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Wellcome Trust","keywords":"Cyclophilin; Isomerase; Spliceosome; Peptidylprolyl isomerase; Cyclophilin A; Biology; PIN1; Biochemistry; Cis-trans-Isomerases; Enzyme; Cell biology; Chemistry; Molecular biology; RNA splicing; RNA","score_opus":0.014507801754012352,"score_gpt":0.2565537206235522,"score_spread":0.24204591886953986,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1516557136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8884686,0.046564784,0.005704643,0.00669236,0.0016190292,0.00016496294,0.015032199,0.0015053008,0.034248196],"genre_scores_gemma":[0.8943005,0.016982624,0.011718368,0.0016095749,0.00018553763,0.00013438014,0.049385276,0.00021355455,0.025470138],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998888,0.000010405364,0.000004851124,0.000024804127,0.000050996598,0.000020103476],"domain_scores_gemma":[0.9999037,0.000020745201,0.000014382326,0.000003926925,0.00002496864,0.00003233352],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028807094,0.00043866446,0.0007041429,0.00020914695,0.0006093163,0.000865524,0.00062590686,0.0006811007,0.003594793],"category_scores_gemma":[0.00042584178,0.0003237984,0.00022320173,0.00040827622,0.0001906744,0.00048642972,0.00034864648,0.0012320657,0.0010027856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0034115664,0.0009969824,0.018444294,0.0031054951,0.00068345,0.004605154,0.0013579213,0.01597931,0.5763661,0.011402782,0.23451619,0.12913068],"study_design_scores_gemma":[0.0019189516,0.001136229,0.10160825,0.00063819706,0.00090480724,0.0055107996,0.002024798,0.08259466,0.2004641,0.0054449863,0.5974249,0.00032934913],"about_ca_topic_score_codex":0.0045135277,"about_ca_topic_score_gemma":0.0061703958,"teacher_disagreement_score":0.0045135277,"about_ca_system_score_codex":0.0010920495,"about_ca_system_score_gemma":0.00089689356,"threshold_uncertainty_score":0.0120257735},"labels":[],"label_agreement":null},{"id":"W1549273904","doi":"10.1002/9780470015902.a0003014.pub2","title":"Proline Residues in Proteins","year":2010,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Polyproline helix; Proline; Hydroxyproline; Chemistry; Prolyl isomerase; Peptidylprolyl isomerase; Protein folding; Protein structure; Biochemistry; Imino acid; Amino acid; Isomerase; Peptide; Enzyme","score_opus":0.011413995602128553,"score_gpt":0.26808489372084726,"score_spread":0.2566708981187187,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1549273904","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5031732,0.33655646,0.039391357,0.00731834,0.0125018945,0.00020448497,0.0016034275,0.0005665442,0.09868439],"genre_scores_gemma":[0.8519025,0.05728443,0.018260434,0.0021020267,0.0015607281,0.00010779935,0.0009681054,0.00009889009,0.06771512],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99985015,0.000026447897,0.000012366808,0.000041104966,0.00004826035,0.00002158744],"domain_scores_gemma":[0.9998648,0.00001377329,0.00005167637,0.000008801616,0.000032285672,0.000028517723],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016515124,0.00043098972,0.00022775475,0.00028330775,0.00058451394,0.00063164695,0.00025799437,0.0006173807,0.0030508211],"category_scores_gemma":[0.00023358373,0.00011992931,0.00016442641,0.00042902294,0.000518283,0.0005338226,0.0005796747,0.00066903257,0.0033671982],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067275076,0.00007967663,0.0015933922,0.0020217702,0.00006233848,0.0027414234,0.00036671583,0.0013009349,0.80241627,0.04554398,0.010251007,0.13294975],"study_design_scores_gemma":[0.000077961486,0.0008938972,0.005870039,0.0002590725,0.000073185256,0.0058196555,0.00026569504,0.0011265465,0.29785958,0.020281699,0.6674114,0.000061263905],"about_ca_topic_score_codex":0.00030177645,"about_ca_topic_score_gemma":0.00024963683,"teacher_disagreement_score":0.0030508211,"about_ca_system_score_codex":0.0003324686,"about_ca_system_score_gemma":0.00023090046,"threshold_uncertainty_score":0.010206044},"labels":[],"label_agreement":null},{"id":"W1564663601","doi":"10.4049/jimmunol.174.6.3212","title":"Impaired Cytolytic Activity in Calreticulin-Deficient CTLs","year":2005,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Perforin; Granzyme; Calreticulin; Cytotoxic T cell; Cell biology; CTL*; Degranulation; Endoplasmic reticulum; Cytolysis; Biology; Granzyme A; Cytotoxicity; Exocytosis; Biochemistry","score_opus":0.011221515088208128,"score_gpt":0.25099999337725454,"score_spread":0.23977847828904642,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1564663601","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969356,0.0002817995,0.0017389357,0.000050798484,0.00002249822,0.000020303829,0.00038308412,0.00009343387,0.00047349755],"genre_scores_gemma":[0.9963831,0.0001771376,0.0013325582,0.000040188766,0.000009792422,0.00003412455,0.0005884902,0.000043735716,0.0013909903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997824,0.000033972432,0.000042873977,0.00004309534,0.000053358694,0.00004430384],"domain_scores_gemma":[0.9996013,0.000096575626,0.000115219074,0.000059704962,0.000039279937,0.000087837056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001721318,0.00044665247,0.0004525956,0.00029625808,0.00012996724,0.00043377804,0.0003070933,0.0006006626,0.0015952477],"category_scores_gemma":[0.00031089404,0.00014275736,0.00026663695,0.00018015938,0.0003496267,0.00027371437,0.00029431807,0.0010544574,0.0006872932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009091107,0.00001749035,0.00013949545,0.000012834639,0.0000029185717,0.00010803352,0.000009517486,0.000065452696,0.9990688,0.000050888248,0.000014619812,0.00041907365],"study_design_scores_gemma":[0.00011449094,0.0006371998,0.006216465,0.000009072094,0.00003462116,0.002174329,0.000044564047,0.0020434065,0.9872327,0.0001139476,0.0013694058,0.000009801613],"about_ca_topic_score_codex":0.00029285724,"about_ca_topic_score_gemma":0.00019588396,"teacher_disagreement_score":0.0015952477,"about_ca_system_score_codex":0.00030668807,"about_ca_system_score_gemma":0.00014545229,"threshold_uncertainty_score":0.0053366423},"labels":[],"label_agreement":null},{"id":"W1565044685","doi":"10.4049/jimmunol.179.7.4694","title":"Early Growth Response 1 and NF-ATc1 Act in Concert to Promote Thymocyte Development beyond the β-Selection Checkpoint","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health","keywords":"EGR1; Transcription factor; Biology; Cell biology; G2-M DNA damage checkpoint; Thymocyte; CD8; Cancer research; Negative selection; Cell cycle checkpoint; Genetics; Apoptosis; Cell cycle; Gene; Antigen; Genome","score_opus":0.009342369559000979,"score_gpt":0.2504227222000355,"score_spread":0.2410803526410345,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1565044685","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98955536,0.0026188688,0.0045301514,0.00011630967,0.00003449119,0.000031933527,0.00034380256,0.00019459915,0.0025745311],"genre_scores_gemma":[0.989349,0.00096543983,0.0040652524,0.00011038025,0.000019393105,0.000054318964,0.000579167,0.00003706967,0.0048199175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980205,0.000023327002,0.000014246109,0.000053645123,0.000043868047,0.000062857376],"domain_scores_gemma":[0.99980646,0.0000253541,0.0000689401,0.000025020983,0.000013492146,0.000060876453],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014679939,0.0007407551,0.00025809745,0.00027928123,0.00013289042,0.00027448294,0.00027348535,0.00027103184,0.0012121905],"category_scores_gemma":[0.00010130078,0.00014994045,0.00036221952,0.00010336604,0.00024098935,0.00018372307,0.00033694075,0.00067367346,0.00048845296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009667035,0.000014531278,0.00031038793,0.000023111686,0.0000041351427,0.000040511513,0.00000851382,0.00004725218,0.9985998,0.00006432053,0.000013826702,0.00077691325],"study_design_scores_gemma":[0.000020695876,0.000274453,0.010193778,0.000006836664,0.00002243981,0.00044047006,0.000029544377,0.00071764743,0.9864022,0.00006919625,0.0018188107,0.0000039287074],"about_ca_topic_score_codex":0.0005018909,"about_ca_topic_score_gemma":0.0008515072,"teacher_disagreement_score":0.0012121905,"about_ca_system_score_codex":0.00031856244,"about_ca_system_score_gemma":0.00030585763,"threshold_uncertainty_score":0.0040551424},"labels":[],"label_agreement":null},{"id":"W1571434015","doi":"10.3389/fpsyt.2015.00085","title":"From Learning to Memory: What Flies Can Tell Us about Intellectual Disability Treatment","year":2015,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women and Children’s Health Research Institute; University of Alberta","funders":"","keywords":"Intellectual disability; CREB; Neuroscience; Model organism; Cyclic adenosine monophosphate; Drosophila (subgenus); Fragile X syndrome; Population; Drosophila melanogaster; Biology; Gene; Medicine; Psychology; Genetics; Receptor; Transcription factor","score_opus":0.023821323289873308,"score_gpt":0.3101208701560744,"score_spread":0.2862995468662011,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1571434015","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000060207727,0.9978021,0.00007668769,0.001003063,0.0003136304,0.0000039020315,0.000022766397,0.000007704545,0.00070986507],"genre_scores_gemma":[0.0006109,0.9976057,0.00017560695,0.0008132895,0.00021666662,0.000009008742,0.000029058841,0.0000018353514,0.00053792406],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997726,0.00006970949,0.000039043145,0.000033312608,0.00006654301,0.000018734285],"domain_scores_gemma":[0.9996221,0.00023060727,0.00003480746,0.000013319028,0.00006664368,0.000032480933],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063927425,0.0007209167,0.0013982668,0.0014365735,0.00039678602,0.0010148939,0.0009877016,0.001865456,0.002992856],"category_scores_gemma":[0.0013117952,0.00026293757,0.0005315631,0.0010173087,0.0006011944,0.0014826893,0.00061958673,0.002386401,0.0016578924],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000090489055,0.00005150834,0.00015543704,0.012960946,0.00014493549,0.00019296857,0.00009798655,0.0002282886,0.0006402115,0.006478656,0.065955184,0.91300344],"study_design_scores_gemma":[0.000025717118,0.000075183205,0.00072318636,0.005959913,0.00010012575,0.00074722053,0.00008674719,0.00006730868,0.00019262746,0.0041589285,0.9878445,0.000018526347],"about_ca_topic_score_codex":0.0021777682,"about_ca_topic_score_gemma":0.003471583,"teacher_disagreement_score":0.002992856,"about_ca_system_score_codex":0.00081643305,"about_ca_system_score_gemma":0.0006165201,"threshold_uncertainty_score":0.01001215},"labels":[],"label_agreement":null},{"id":"W1574890201","doi":"10.4049/jimmunol.178.supp.94.19","title":"Cyclosporin A and FK506 Inhibit IL-12p40 Production through the Calmodulin/Calmodulin-dependent Protein Kinase-activated PI3K in LPS-Stimulated Human Monocytic Cells (94.19)","year":2007,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"CAMK; Calmodulin; Calcineurin; Cell biology; PI3K/AKT/mTOR pathway; Kinase; Protein kinase A; Phosphoinositide 3-kinase; Biology; Transcription factor; Signal transduction; Internal medicine; Medicine; Biochemistry; Gene; Enzyme","score_opus":0.016360081585260425,"score_gpt":0.2670951425821544,"score_spread":0.25073506099689397,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1574890201","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867025,0.0044467757,0.0032029625,0.0003127989,0.00017085,0.00011460266,0.0016925033,0.00023897321,0.003117946],"genre_scores_gemma":[0.9902075,0.0019334013,0.0022332654,0.00012441333,0.00005612183,0.0001510446,0.0014895346,0.000018857641,0.0037859504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999876,0.000018184275,0.000016971184,0.000015985323,0.000025702922,0.0000471247],"domain_scores_gemma":[0.9999263,0.00001408045,0.00001574474,0.000011038093,0.000008746477,0.000024143788],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000107862004,0.0003894267,0.00031218305,0.00022539227,0.00020680505,0.00028591428,0.00015220825,0.00023020033,0.002090185],"category_scores_gemma":[0.00010337472,0.0001286905,0.00036315186,0.0002073668,0.00017830565,0.000114785944,0.00013554574,0.0006464928,0.0007940011],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052457995,0.00007845118,0.00012163186,0.000062694606,0.000005339449,0.0000576445,0.000015283424,0.00004622431,0.9975916,0.000055374247,0.00014718775,0.0012940502],"study_design_scores_gemma":[0.00018779593,0.0013404407,0.008619762,0.000010455602,0.000033552315,0.000233538,0.000027521162,0.00091105414,0.9843629,0.000042849162,0.0042241756,0.000005984693],"about_ca_topic_score_codex":0.001517908,"about_ca_topic_score_gemma":0.0019005294,"teacher_disagreement_score":0.002090185,"about_ca_system_score_codex":0.00023195431,"about_ca_system_score_gemma":0.00030759818,"threshold_uncertainty_score":0.00699234},"labels":[],"label_agreement":null},{"id":"W1580358117","doi":"10.1002/0471203076.emm0130","title":"Myelin Associated Glycoprotein","year":2002,"lang":"en","type":"other","venue":"Wiley Encyclopedia of Molecular Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Encyclopedia; Citation; Computer science; Library science; Information retrieval; Operations research; Engineering","score_opus":0.007842835024841944,"score_gpt":0.23552332918408345,"score_spread":0.2276804941592415,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1580358117","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.016417926,0.08882491,0.022385279,0.002189776,0.002681762,0.00036384814,0.009880335,0.0044465708,0.85280955],"genre_scores_gemma":[0.02810223,0.03387869,0.010228562,0.0008765092,0.00029933648,0.00016994547,0.010937912,0.0003757952,0.91513103],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998739,0.000011385613,0.000006358454,0.00003058474,0.000050820185,0.000027057766],"domain_scores_gemma":[0.9999318,0.000007798738,0.000008222494,0.000009679582,0.000016480228,0.000025976142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016771127,0.0012031129,0.00066338904,0.0016902915,0.00056982884,0.0012407777,0.00076847785,0.00069390656,0.15179162],"category_scores_gemma":[0.0002629298,0.00021989424,0.00038133335,0.0014310523,0.00023415391,0.0006040516,0.0010438657,0.0009615316,0.17476195],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042485006,0.00016989505,0.0005496894,0.00084333104,0.000052866013,0.0010095064,0.000056552108,0.0003120108,0.14783818,0.013987938,0.2693985,0.56535673],"study_design_scores_gemma":[0.000020142099,0.000056498044,0.00096352503,0.00007735015,0.000027770047,0.0013604771,0.000016982453,0.00015566767,0.022180011,0.0017706733,0.9733589,0.000011909059],"about_ca_topic_score_codex":0.00074320764,"about_ca_topic_score_gemma":0.0013229866,"teacher_disagreement_score":0.15179162,"about_ca_system_score_codex":0.00044291816,"about_ca_system_score_gemma":0.00045589352,"threshold_uncertainty_score":0.50779355},"labels":[],"label_agreement":null},{"id":"W1627591531","doi":"10.2353/ajpath.2009.080385","title":"Valproate Attenuates Accelerated Atherosclerosis in Hyperglycemic ApoE-Deficient Mice","year":2008,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":92,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Endocrinology; Internal medicine; Inflammation; In vivo; Cholesterol; Chemistry; Unfolded protein response; Apolipoprotein E; Endoplasmic reticulum; GSK-3; Apolipoprotein B; Leptin; Medicine; Biology; Kinase; Biochemistry","score_opus":0.025142009681827265,"score_gpt":0.2585576670753952,"score_spread":0.23341565739356793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1627591531","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939567,0.0013706812,0.001387384,0.0004934128,0.00017541957,0.000035870547,0.0007109624,0.0003468488,0.0015228731],"genre_scores_gemma":[0.9901904,0.0017471579,0.0017878147,0.00029523668,0.00011589354,0.000086711065,0.00081825,0.00015146275,0.0048070084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995542,0.0000942006,0.000055211884,0.00007423891,0.00008228006,0.00013980235],"domain_scores_gemma":[0.99936765,0.000057887733,0.0001985814,0.0000792411,0.00004945992,0.00024714659],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003513403,0.0013373188,0.0011628611,0.00093571603,0.00040927358,0.0008323071,0.00076000614,0.0010635448,0.0018668816],"category_scores_gemma":[0.00040055954,0.00062232243,0.00058047083,0.00043669934,0.0007116531,0.0006137672,0.00031169294,0.0021831838,0.00075138116],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.01632911,0.00077858224,0.0004894037,0.000097298034,0.00007646105,0.00032005986,0.000057268106,0.00029770785,0.9765671,0.00043274785,0.00031372628,0.0042404663],"study_design_scores_gemma":[0.0021601468,0.0047587887,0.0080064675,0.000044320506,0.0002823925,0.00053863873,0.00017508032,0.0026982469,0.977246,0.0006283425,0.003415726,0.00004586343],"about_ca_topic_score_codex":0.0016223112,"about_ca_topic_score_gemma":0.0021964107,"teacher_disagreement_score":0.0018668816,"about_ca_system_score_codex":0.0005788159,"about_ca_system_score_gemma":0.00068371807,"threshold_uncertainty_score":0.006245315},"labels":[],"label_agreement":null},{"id":"W1684263064","doi":"10.1111/j.1471-4159.2005.03092.x","title":"Changes in calcineurin expression induced in the rat brain by the administration of antipsychotics","year":2005,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Western University","funders":"Health Canada; Canadian Psychiatric Research Foundation; National Alliance for Research on Schizophrenia and Depression","keywords":"Haloperidol; Risperidone; Antipsychotic; Schizophrenia (object-oriented programming); Calcineurin; Clozapine; Prefrontal cortex; Typical antipsychotic; Psychosis; Pharmacology; Striatum; Dopamine; Endocrinology; Internal medicine; Medicine; Atypical antipsychotic; Psychiatry; Transplantation","score_opus":0.019207910096566104,"score_gpt":0.29557202262943766,"score_spread":0.2763641125328716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1684263064","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914357,0.004303116,0.001776946,0.0001653358,0.00005440981,0.000021656295,0.00042212367,0.00015100844,0.0016697401],"genre_scores_gemma":[0.9867029,0.0038498351,0.003962243,0.00009119488,0.00003035132,0.0000563054,0.00089918385,0.00004094071,0.0043670884],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998617,0.000019096053,0.000006845773,0.000026066087,0.00003801773,0.000048254515],"domain_scores_gemma":[0.99980277,0.000033878263,0.000059517264,0.00002598141,0.000021644033,0.00005626207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016509615,0.00050633325,0.00033585215,0.00071702903,0.00026492978,0.00035695927,0.00022345535,0.00033784992,0.0011656099],"category_scores_gemma":[0.0002010078,0.00029319583,0.00028808523,0.00033270323,0.0005735759,0.0002853046,0.00016355561,0.0008330311,0.00034185106],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004570772,0.00003531781,0.00018565754,0.000027848084,0.0000097213315,0.00008084443,0.000019042247,0.000028456492,0.99802727,0.00006617153,0.000027508662,0.0010349336],"study_design_scores_gemma":[0.00006913365,0.0012128897,0.012643966,0.000011404055,0.00005745818,0.00035525596,0.00006560816,0.0006273702,0.9836976,0.00016706038,0.0010802154,0.000012026237],"about_ca_topic_score_codex":0.0029781542,"about_ca_topic_score_gemma":0.00615054,"teacher_disagreement_score":0.0029781542,"about_ca_system_score_codex":0.0005739196,"about_ca_system_score_gemma":0.0005260552,"threshold_uncertainty_score":0.0059216022},"labels":[],"label_agreement":null},{"id":"W1846608835","doi":"10.1523/jneurosci.23-35-11127.2003","title":"Matrix Metalloproteinase-9 Facilitates Remyelination in Part by Processing the Inhibitory NG2 Proteoglycan","year":2003,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":265,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Fondation pour la Recherche Médicale; Canadian Institutes of Health Research; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada","keywords":"Remyelination; Matrix metalloproteinase; Downregulation and upregulation; Neuroscience; Myelin; Extracellular matrix; Inhibitory postsynaptic potential; Cell biology; Multiple sclerosis; Proteoglycan; Biology; Chemistry; Immunology; Central nervous system; Biochemistry","score_opus":0.016480733193790356,"score_gpt":0.2722911991413898,"score_spread":0.25581046594759943,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1846608835","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942094,0.0012949151,0.0026494667,0.000102303144,0.00001706842,0.0000120253835,0.00020257625,0.000069271824,0.0014429524],"genre_scores_gemma":[0.9961358,0.0006504177,0.0013818444,0.000013264351,0.000005306684,0.00001128784,0.00014717046,0.000009000034,0.0016458441],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998814,0.000023373168,0.0000103783705,0.000024723506,0.00002732014,0.00003282766],"domain_scores_gemma":[0.9998549,0.000021465252,0.00005330138,0.000018562885,0.000015306123,0.000036498546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016453117,0.00044128424,0.00020842809,0.00017103007,0.000110165805,0.00036664214,0.0001918547,0.00021819276,0.001125986],"category_scores_gemma":[0.00016981183,0.00010449055,0.00014672871,0.000075483724,0.00028290987,0.0002604617,0.00025700743,0.00043942843,0.0004087209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000614801,0.000010592758,0.00024257855,0.000018958573,0.0000019909319,0.000060214432,0.000006217388,0.0000210356,0.99874437,0.00010216538,0.000016282887,0.0007141638],"study_design_scores_gemma":[0.000014198942,0.00018331871,0.005298206,0.0000050699305,0.000010494775,0.0003810485,0.000018349177,0.00030169025,0.9921205,0.00010474423,0.0015604618,0.0000019068091],"about_ca_topic_score_codex":0.00037036467,"about_ca_topic_score_gemma":0.00064960285,"teacher_disagreement_score":0.001125986,"about_ca_system_score_codex":0.00021375544,"about_ca_system_score_gemma":0.00018125279,"threshold_uncertainty_score":0.0037668347},"labels":[],"label_agreement":null},{"id":"W1859819500","doi":"10.1111/j.1742-4658.2007.05707.x","title":"Solution structure of the catalytic domain of RICH protein from goldfish","year":2007,"lang":"en","type":"article","venue":"FEBS Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; William Osler Health System","funders":"University of Michigan","keywords":"Antiparallel (mathematics); Hydrolase; Nucleotide; Biology; Phosphodiesterase; Residual dipolar coupling; Protein structure; Active site; Biophysics; Biochemistry; Stereochemistry; Cell biology; Chemistry; Enzyme; Nuclear magnetic resonance spectroscopy","score_opus":0.006840107275962527,"score_gpt":0.22837818401337664,"score_spread":0.22153807673741413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1859819500","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98928905,0.0028685285,0.0035080279,0.00032212428,0.000054825272,0.000037710048,0.0010854593,0.00010508853,0.0027292164],"genre_scores_gemma":[0.9782171,0.0017856616,0.0073308363,0.0001646544,0.000018575221,0.00003383956,0.0090545155,0.00005606648,0.0033387097],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994636,0.000004507349,0.0000036399908,0.000018220275,0.000016303044,0.000010875207],"domain_scores_gemma":[0.9999201,0.000014456987,0.000013412929,0.0000064748015,0.000019375422,0.000026006475],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016177903,0.00043013314,0.00041541396,0.00012521913,0.00032467936,0.00038026678,0.0008120702,0.0006101159,0.001325663],"category_scores_gemma":[0.0002688363,0.00027404702,0.0002267044,0.00020706057,0.00026114998,0.00030871487,0.00020934964,0.0007757672,0.0004609428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011149204,0.00017922246,0.0052643265,0.00064829184,0.00013240948,0.001608328,0.0005456906,0.01347313,0.95777774,0.002016897,0.0025736769,0.0146652935],"study_design_scores_gemma":[0.0010501574,0.0018263763,0.08749847,0.00025820296,0.00043559473,0.0031024967,0.0014540417,0.114639,0.72240347,0.0056722346,0.061401766,0.00025816282],"about_ca_topic_score_codex":0.0053363345,"about_ca_topic_score_gemma":0.0038391175,"teacher_disagreement_score":0.0053363345,"about_ca_system_score_codex":0.00097084884,"about_ca_system_score_gemma":0.0005714543,"threshold_uncertainty_score":0.01061058},"labels":[],"label_agreement":null},{"id":"W1861248750","doi":"10.1007/978-1-4615-1723-8_3","title":"Functional specialization of CK2 isoforms and characterization of isoform-specific binding partners","year":2001,"lang":"en","type":"article","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Gene isoform; Biology; Casein kinase 2; Isozyme; Protein subunit; Pleckstrin homology domain; Cell biology; Leucine zipper; Biochemistry; Kinase; Protein kinase A; Enzyme; Gene; Peptide sequence; Cyclin-dependent kinase 2","score_opus":0.024081244322426934,"score_gpt":0.25134011876872936,"score_spread":0.22725887444630244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1861248750","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98228514,0.0057528634,0.008317378,0.00021497553,0.000043155524,0.000027374532,0.0006611235,0.00006816313,0.0026297402],"genre_scores_gemma":[0.98830694,0.0018135675,0.0049192957,0.00008078218,0.000028389983,0.000036447374,0.0013546688,0.000043823235,0.003416093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982494,0.000025327017,0.0000157519,0.000044391923,0.000031602154,0.00005806896],"domain_scores_gemma":[0.99975127,0.00006689556,0.00003159696,0.00003764275,0.00004633684,0.00006625961],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032848466,0.000425792,0.00037318355,0.0005279321,0.00037706055,0.000613229,0.00039922795,0.00034396013,0.0024946502],"category_scores_gemma":[0.00045295875,0.00029783943,0.00039842518,0.0003813497,0.00019669285,0.0004957613,0.00026607752,0.00052402087,0.0007325159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017920116,0.000016331715,0.0008690402,0.000035065827,0.00001276516,0.000100576544,0.00002205584,0.00010832437,0.9966737,0.00026027506,0.000061252606,0.0016614419],"study_design_scores_gemma":[0.000024447036,0.000060280585,0.03007654,0.000009288726,0.000050377846,0.001394913,0.00007498292,0.0030317288,0.9588141,0.0003438691,0.0061020833,0.000017356304],"about_ca_topic_score_codex":0.0017418723,"about_ca_topic_score_gemma":0.0021889263,"teacher_disagreement_score":0.0024946502,"about_ca_system_score_codex":0.00055934215,"about_ca_system_score_gemma":0.00022137185,"threshold_uncertainty_score":0.008345485},"labels":[],"label_agreement":null},{"id":"W1872514198","doi":"10.1042/bj3640089","title":"Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene","year":2002,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Calgary","funders":"","keywords":"Molecular biology; Biology; TATA box; CAAT box; Promoter; Gene expression; Gene; Reporter gene; Exon; Intron; Genetics","score_opus":0.015259821637943115,"score_gpt":0.2682376796289755,"score_spread":0.2529778579910324,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1872514198","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9540723,0.002166627,0.038144834,0.00025317416,0.00015999902,0.00014362764,0.0028483495,0.0003693181,0.0018418233],"genre_scores_gemma":[0.9034184,0.0015105145,0.07350576,0.0001785426,0.00006774361,0.00030499932,0.010489195,0.00019056744,0.010334303],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996947,0.00004307981,0.0000290774,0.00007776858,0.00010188597,0.000053470816],"domain_scores_gemma":[0.99944705,0.00020104765,0.00015307212,0.000058304442,0.000064146145,0.000076422395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000398816,0.00050882733,0.00039204498,0.0005038761,0.00017145331,0.00035393357,0.0003494651,0.00038875538,0.0027408742],"category_scores_gemma":[0.00046246315,0.00025532756,0.000695313,0.000181333,0.00031905848,0.00023389306,0.00029921328,0.0009408936,0.0013765837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002940623,0.000009700244,0.00013474065,0.000021060267,0.000002132231,0.00003617863,0.000007692451,0.0000209205,0.9991091,0.0000370517,0.000012097632,0.0005799649],"study_design_scores_gemma":[0.000014336086,0.000204249,0.0036039301,0.000010900121,0.000021364638,0.00031564667,0.000016931826,0.0006227903,0.9917604,0.00007982457,0.0033433721,0.0000062002987],"about_ca_topic_score_codex":0.00021065779,"about_ca_topic_score_gemma":0.00035178268,"teacher_disagreement_score":0.0027408742,"about_ca_system_score_codex":0.0003016108,"about_ca_system_score_gemma":0.00044928247,"threshold_uncertainty_score":0.009169102},"labels":[],"label_agreement":null},{"id":"W1887319299","doi":"10.1038/emboj.2011.55","title":"Myelin suppresses axon regeneration by PIR‐B/SHP‐mediated inhibition of Trk activity","year":2011,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; School of Medicine, New York University; York University","keywords":"Biology; Trk receptor; Regeneration (biology); Axon; Myelin; Cell biology; Neuroscience; Neurotrophin; Biochemistry; Central nervous system; Receptor","score_opus":0.022815685537387984,"score_gpt":0.23537724744550023,"score_spread":0.21256156190811226,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1887319299","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915446,0.001350928,0.0026438157,0.00024015602,0.0000715759,0.00001762064,0.00044220386,0.00034187915,0.0033471985],"genre_scores_gemma":[0.9947836,0.00046923087,0.0014494415,0.000050591276,0.000017907576,0.000032722986,0.00036241274,0.00006302434,0.0027710723],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973124,0.000035406836,0.000026134217,0.00004604448,0.000065675915,0.00009552409],"domain_scores_gemma":[0.9997665,0.00003888287,0.000049646886,0.00003494201,0.000014163943,0.00009576298],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024326834,0.00057076267,0.00029945528,0.00047642007,0.00032126618,0.0005470057,0.0005530058,0.0005153988,0.004124924],"category_scores_gemma":[0.00023494556,0.00028354497,0.00035613432,0.00022589894,0.00067428267,0.0004178456,0.00069239025,0.0016423161,0.001192258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024327532,0.000034144232,0.00007499724,0.000036910442,0.000009115801,0.000065773,0.000008147977,0.000057605183,0.9982697,0.00018082274,0.00007211856,0.0009473629],"study_design_scores_gemma":[0.000038932,0.00018785853,0.0013703,0.0000057153056,0.000013308573,0.00026180054,0.000025722322,0.0007972354,0.9956951,0.00011815366,0.0014800729,0.000005789297],"about_ca_topic_score_codex":0.0006892154,"about_ca_topic_score_gemma":0.0009589686,"teacher_disagreement_score":0.004124924,"about_ca_system_score_codex":0.0003793191,"about_ca_system_score_gemma":0.00037153592,"threshold_uncertainty_score":0.0137991905},"labels":[],"label_agreement":null},{"id":"W1922670199","doi":"10.4049/jimmunol.1301271","title":"Calcineurin–Rcan1 Interaction Contributes to Stem Cell Factor–Mediated Mast Cell Activation","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"NFAT; Calcineurin; Stem cell factor; Cell biology; Transcription factor; Stem cell; Progenitor cell; Signal transduction; Biology; Mast cell; Haematopoiesis; Chemistry; Transplantation; Immunology; Internal medicine; Biochemistry; Medicine","score_opus":0.010790403169337232,"score_gpt":0.2303602342518022,"score_spread":0.21956983108246494,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1922670199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855341,0.008436193,0.00386417,0.0001777302,0.000034229506,0.000035762365,0.00022975443,0.00009710284,0.0015911164],"genre_scores_gemma":[0.9936445,0.0024017566,0.0017414262,0.00005906932,0.000022181077,0.000018921435,0.00039949783,0.000010403669,0.0017022855],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998323,0.00002223446,0.000010401978,0.00004009626,0.00005268147,0.000042271287],"domain_scores_gemma":[0.9998946,0.000012413371,0.000037101632,0.000008998242,0.000012357349,0.000034533026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017018206,0.00056178763,0.00025526062,0.00029047419,0.00025471434,0.00037670537,0.00027770113,0.00033808273,0.0010607798],"category_scores_gemma":[0.00010287203,0.00012365879,0.00036398284,0.00013216908,0.00023033886,0.00024313756,0.00026194943,0.00047862064,0.00025409172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060375103,0.000017903492,0.00043168865,0.00004928363,0.000006176953,0.00013390573,0.000015360856,0.000054925466,0.99793905,0.00013565147,0.00002735367,0.0011281754],"study_design_scores_gemma":[0.00001710563,0.00012483569,0.017689373,0.000010199677,0.00003721803,0.0006846887,0.000038546663,0.002248944,0.97384363,0.00014640148,0.005150674,0.000008462008],"about_ca_topic_score_codex":0.00055242365,"about_ca_topic_score_gemma":0.00094547804,"teacher_disagreement_score":0.0010607798,"about_ca_system_score_codex":0.0004295748,"about_ca_system_score_gemma":0.00023821443,"threshold_uncertainty_score":0.0035486817},"labels":[],"label_agreement":null},{"id":"W1930134848","doi":"10.1371/journal.pone.0136692","title":"Characterization of Peptidyl-Prolyl Cis-Trans Isomerase- and Calmodulin-Binding Activity of a Cytosolic Arabidopsis thaliana Cyclophilin AtCyp19-3","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"University Grants Commission","keywords":"Cyclophilin; Peptidylprolyl isomerase; Calmodulin; Cis-trans-Isomerases; Cytosol; Arabidopsis thaliana; FKBP; Prolyl isomerase; Isomerase; PIN1; Biochemistry; Biology; Chemistry; Cell biology; Enzyme; Gene","score_opus":0.0471611527034535,"score_gpt":0.23919881102566323,"score_spread":0.19203765832220973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1930134848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99659914,0.0005519053,0.001625391,0.000056334375,0.0000071561926,0.000018345869,0.0005922076,0.00002050433,0.00052902877],"genre_scores_gemma":[0.9942954,0.00032313936,0.0020604427,0.00004262892,0.000008618126,0.000015090083,0.002213104,0.000013959333,0.0010275554],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995506,0.0000053903996,0.0000033600043,0.000012061637,0.000015752357,0.000008406642],"domain_scores_gemma":[0.9999069,0.000015087668,0.00002820899,0.000008343254,0.000012063782,0.00002935185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000049448667,0.00025255728,0.00015743716,0.00015442992,0.00008922435,0.0001352551,0.00012214373,0.00014531698,0.00047693757],"category_scores_gemma":[0.00009683752,0.00005643353,0.00021181263,0.00012736568,0.00008431673,0.00008383775,0.000069718415,0.00027342225,0.0001849374],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000018220762,0.000004135817,0.000107025146,0.0000055843943,0.0000011455762,0.000016579546,0.0000021609428,0.00001020777,0.99960893,0.000007102636,0.0000035578585,0.00021535592],"study_design_scores_gemma":[0.000014634437,0.00015526004,0.032813407,0.000003186507,0.000017304073,0.0005798107,0.000020457272,0.0011977281,0.96342057,0.000027860522,0.0017454468,0.0000042928814],"about_ca_topic_score_codex":0.0010390438,"about_ca_topic_score_gemma":0.0011568062,"teacher_disagreement_score":0.0010390438,"about_ca_system_score_codex":0.00022064256,"about_ca_system_score_gemma":0.00011144152,"threshold_uncertainty_score":0.0020659566},"labels":[],"label_agreement":null},{"id":"W1964046410","doi":"10.1016/j.cardfail.2006.06.094","title":"Vitronectin Deficient Mice Exhibit Improved Healing and Function Following Myocardial Infarction","year":2006,"lang":"en","type":"article","venue":"Journal of Cardiac Failure","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Vitronectin; Myocardial infarction; Cardiology; Internal medicine; Wound healing; Surgery; Integrin; Receptor","score_opus":0.0042014682471797835,"score_gpt":0.21142581893767745,"score_spread":0.20722435069049766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964046410","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936009,0.0013137017,0.0023473792,0.0002858462,0.00010657198,0.000023081151,0.00073194207,0.00018275113,0.0014077836],"genre_scores_gemma":[0.9870406,0.00093878846,0.002041408,0.00017183207,0.000043492797,0.00007468613,0.00073423225,0.00016546092,0.008789566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995889,0.00005875545,0.000045043347,0.00009110841,0.0001039048,0.00011226016],"domain_scores_gemma":[0.9988391,0.00008583441,0.0004520178,0.00010025694,0.000045480356,0.00047739226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029352083,0.00088092935,0.00082374003,0.0012638506,0.00031450752,0.0008246353,0.00064267876,0.0013317601,0.0037400385],"category_scores_gemma":[0.0003173009,0.0006221644,0.00041562077,0.0003483234,0.0008821625,0.00062730134,0.00048432665,0.0023015211,0.0009886831],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063957745,0.00007778333,0.00021089848,0.00002774963,0.000011113002,0.00022717087,0.000019011988,0.00008399522,0.99758124,0.00016321875,0.00006488078,0.0008934421],"study_design_scores_gemma":[0.00022000825,0.0008923967,0.015578993,0.000036438665,0.00009922187,0.0024867137,0.00019364273,0.001458755,0.9758537,0.00045746952,0.002690628,0.000032088632],"about_ca_topic_score_codex":0.00034801968,"about_ca_topic_score_gemma":0.00076731027,"teacher_disagreement_score":0.0037400385,"about_ca_system_score_codex":0.0004781589,"about_ca_system_score_gemma":0.00022637953,"threshold_uncertainty_score":0.012511671},"labels":[],"label_agreement":null},{"id":"W1964249602","doi":"10.1016/j.cellsig.2013.08.033","title":"Structural basis of calcineurin activation by calmodulin","year":2013,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Calcineurin; Calmodulin; Antiparallel (mathematics); Protein subunit; Active site; Phosphatase; Chemistry; Biophysics; Structural biology; Binding site; Biochemistry; Cell biology; Biology; Enzyme","score_opus":0.010382266487646891,"score_gpt":0.21575465508710448,"score_spread":0.20537238859945758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964249602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96189123,0.0023996213,0.020049525,0.002216125,0.00028676202,0.00008954147,0.0002882943,0.00028144306,0.01249745],"genre_scores_gemma":[0.9958454,0.00046827475,0.0017786897,0.0001420963,0.000033154076,0.000016915623,0.00015263371,0.0000101783035,0.0015526944],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999387,0.000010190378,0.0000043498644,0.000015215713,0.000016757214,0.000014725903],"domain_scores_gemma":[0.9999007,0.000026879688,0.000019804196,0.000012065651,0.000012026294,0.000028548026],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118701355,0.00026846468,0.00021198641,0.000115168375,0.00041496576,0.00028462755,0.00058399665,0.00047539594,0.0027226626],"category_scores_gemma":[0.00023758522,0.00016474405,0.00022795136,0.000081408776,0.00041665314,0.00023712445,0.0002446628,0.00078955747,0.0005801456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027665176,0.000048190403,0.00022194049,0.00006955784,0.000010030883,0.00051963207,0.00005151521,0.001157064,0.98250705,0.012372721,0.00026766973,0.0024978952],"study_design_scores_gemma":[0.00012576256,0.0003052979,0.0034355565,0.000017146553,0.000017329374,0.00086180266,0.00006172774,0.010747892,0.96919036,0.0056444337,0.009569469,0.00002320495],"about_ca_topic_score_codex":0.0009166539,"about_ca_topic_score_gemma":0.00075827,"teacher_disagreement_score":0.0027226626,"about_ca_system_score_codex":0.0005031643,"about_ca_system_score_gemma":0.00029101165,"threshold_uncertainty_score":0.009108186},"labels":[],"label_agreement":null},{"id":"W1964356138","doi":"10.1016/j.bbrc.2007.08.197","title":"Mitotic regulation of CDK4 by the serine/threonine phosphatase, calcineurin","year":2007,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Calcineurin; Phosphorylation; Mitosis; Cell biology; Serine; Threonine; Phosphatase; Biology; Biochemistry; Cyclin-dependent kinase; Kinase; Cell cycle; Chemistry; Cell; Transplantation; Internal medicine","score_opus":0.04858100956641007,"score_gpt":0.3654052349497927,"score_spread":0.3168242253833826,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1964356138","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9786043,0.010480558,0.002153262,0.00039807416,0.0000980206,0.000013388369,0.00016993035,0.00010572035,0.007976743],"genre_scores_gemma":[0.9932632,0.002219914,0.0005594457,0.00004424824,0.00002165615,0.000006693795,0.00013811557,0.000021999134,0.0037247718],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999193,0.000014830755,0.0000059832355,0.000013864395,0.000018737232,0.00002736141],"domain_scores_gemma":[0.99987984,0.000024494833,0.000035153982,0.00001216105,0.000025044881,0.000023296203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014041785,0.00023220568,0.00014251989,0.00036382469,0.00039120848,0.0007591054,0.00024790064,0.00017148453,0.001705897],"category_scores_gemma":[0.0003886029,0.00016167802,0.00014753625,0.00018965121,0.00028418802,0.00030145815,0.0002593753,0.00026468237,0.00034587437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010321578,0.000042765798,0.001755804,0.0000778453,0.000017397335,0.00021735195,0.000043886143,0.00042589023,0.9833524,0.0026094862,0.0003779093,0.010047128],"study_design_scores_gemma":[0.000087603185,0.00017580783,0.018303087,0.000015564714,0.000030533112,0.0003968904,0.00011302819,0.0033152185,0.96664965,0.0008938478,0.010007246,0.000011519938],"about_ca_topic_score_codex":0.0023941156,"about_ca_topic_score_gemma":0.0044757784,"teacher_disagreement_score":0.0023941156,"about_ca_system_score_codex":0.0011210296,"about_ca_system_score_gemma":0.00056458294,"threshold_uncertainty_score":0.00813365},"labels":[],"label_agreement":null},{"id":"W1965115046","doi":"10.1139/bcb-2012-0021","title":"Proteomics based detection of differentially expressed proteins in human osteoblasts subjected to mechanical stress","year":2013,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Natural Science Foundation of China","keywords":"Downregulation and upregulation; Cell biology; Proteomics; Osteoblast; Alkaline phosphatase; Chemistry; Mechanotransduction; Protein turnover; Cytoskeleton; Biology; Molecular biology; Biochemistry; Cell; Protein biosynthesis; Enzyme","score_opus":0.006755790673966223,"score_gpt":0.2164859641429705,"score_spread":0.20973017346900427,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965115046","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988191,0.0037186285,0.0059706806,0.00013507121,0.00005219382,0.000047430647,0.0010861437,0.000056609297,0.00074225856],"genre_scores_gemma":[0.971321,0.0050913235,0.018776452,0.00031642392,0.00005802865,0.00015441241,0.0024067601,0.000025143103,0.0018504794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979824,0.00002103636,0.000013993392,0.000050409108,0.000085518644,0.00003078606],"domain_scores_gemma":[0.99992466,0.000016063812,0.00001932948,0.000004900485,0.000023201972,0.000011800447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022749473,0.00029004746,0.000338311,0.00050310243,0.00020731718,0.00028015382,0.00012735014,0.00038928702,0.00043435773],"category_scores_gemma":[0.0002209107,0.00013854323,0.00024189336,0.0005386218,0.00015957636,0.00014053879,0.00020578518,0.0003167034,0.00022081278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005900176,0.0000096493695,0.00077182666,0.00003612519,0.000007406342,0.000055403296,0.000014876198,0.000017459692,0.99812824,0.000009927855,0.000022076529,0.00086805667],"study_design_scores_gemma":[0.00003556009,0.00042240036,0.15972023,0.000023180475,0.00011608766,0.0014344718,0.00027754708,0.002232226,0.832235,0.00018003052,0.0032997793,0.000023659568],"about_ca_topic_score_codex":0.00048589217,"about_ca_topic_score_gemma":0.0006265712,"teacher_disagreement_score":0.00050310243,"about_ca_system_score_codex":0.000120397955,"about_ca_system_score_gemma":0.00017384274,"threshold_uncertainty_score":0.0014531016},"labels":[],"label_agreement":null},{"id":"W1965445778","doi":"10.1371/journal.pone.0018919","title":"Structural and Histone Binding Ability Characterizations of Human PWWP Domains","year":2011,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":181,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Biological and Environmental Research; Division of Materials Research; Office of Science; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Stiftelsen för Strategisk Forskning; National Center for Research Resources; Ontario Genomics Institute; Wellcome Trust; National Institutes of Health; Ontario Genomics; Genome Canada; Ontario Innovation Trust; GlaxoSmithKline; Brookhaven National Laboratory; Argonne National Laboratory; U.S. Department of Energy; University of Chicago; Canadian Institutes of Health Research; National Science Foundation","keywords":"Chromodomain; Histone; Chemistry; DNA-binding domain; Biology; DNA; Biochemistry; Transcription factor; Gene","score_opus":0.05893307122488449,"score_gpt":0.2608191659931047,"score_spread":0.20188609476822017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965445778","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960259,0.00092441926,0.0019377121,0.000026669459,0.0000036816225,0.000008683576,0.00058204005,0.000014549357,0.00047624865],"genre_scores_gemma":[0.99403536,0.00035962946,0.0024411788,0.000021986969,0.000005296222,0.000014641883,0.002529319,0.000007581815,0.0005849433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999504,0.0000052332216,0.000004258115,0.000013918561,0.000017280152,0.000008887504],"domain_scores_gemma":[0.9998772,0.000031833213,0.000028389672,0.000012990255,0.00002670949,0.000022883036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010594426,0.000244384,0.00012271026,0.00021141859,0.00011786007,0.00013060182,0.00018359978,0.00015548179,0.0009871969],"category_scores_gemma":[0.00021511898,0.00006573137,0.00023674766,0.00032497017,0.00012038899,0.00014198477,0.00011057712,0.00023861746,0.0002561236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028817667,0.000055269375,0.0050857477,0.000112943875,0.000023969156,0.00022709508,0.000099492565,0.00092498603,0.987575,0.00024633174,0.00017022024,0.005190719],"study_design_scores_gemma":[0.000037790996,0.00033526582,0.06546677,0.000015783708,0.000065555556,0.00227701,0.00013746558,0.0075346665,0.9143719,0.00033586807,0.009403839,0.000018053965],"about_ca_topic_score_codex":0.00080272165,"about_ca_topic_score_gemma":0.0004292535,"teacher_disagreement_score":0.0009871969,"about_ca_system_score_codex":0.00018427098,"about_ca_system_score_gemma":0.00008515887,"threshold_uncertainty_score":0.0033025146},"labels":[],"label_agreement":null},{"id":"W1965584484","doi":"10.1002/chin.200808200","title":"ChemInform Abstract: Concise Biomimetic Total Syntheses of Both Antipodes of Balasubramide.","year":2008,"lang":"en","type":"article","venue":"ChemInform","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Antipodes; Nanotechnology; Combinatorial chemistry; Information retrieval; Computer science; Geography","score_opus":0.019436532579128207,"score_gpt":0.2407269060380129,"score_spread":0.2212903734588847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965584484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.34115666,0.06788322,0.30102676,0.0038513157,0.0092249205,0.0031901414,0.019575285,0.0056065293,0.24848516],"genre_scores_gemma":[0.7493178,0.07409112,0.06626856,0.0017021106,0.0006386023,0.0014222834,0.007920522,0.00084867893,0.09779031],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998043,0.000022792836,0.000018677043,0.000026742966,0.00006453448,0.000063007865],"domain_scores_gemma":[0.99992645,0.000008036575,0.000014602962,0.000009685569,0.000013492466,0.000027691714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034333454,0.0012700061,0.0006805913,0.0010015897,0.0004781133,0.00038323586,0.0009021246,0.00036769733,0.012763658],"category_scores_gemma":[0.00028847164,0.0004037809,0.0005018435,0.0008311369,0.0003339779,0.0010980138,0.0010471172,0.0014658888,0.00524317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008142865,0.0005212294,0.00021586285,0.003832191,0.0002643619,0.0015624217,0.00056942075,0.0054410947,0.68841046,0.021005655,0.038966153,0.23839697],"study_design_scores_gemma":[0.00033116326,0.0018386041,0.0011721933,0.0002783108,0.00016433114,0.001185235,0.0001661861,0.001660395,0.73789674,0.0068275654,0.24832541,0.0001538513],"about_ca_topic_score_codex":0.00073834095,"about_ca_topic_score_gemma":0.0014828854,"teacher_disagreement_score":0.012763658,"about_ca_system_score_codex":0.00043254075,"about_ca_system_score_gemma":0.0012638242,"threshold_uncertainty_score":0.04269868},"labels":[],"label_agreement":null},{"id":"W1965635486","doi":"10.1016/s0041-1345(01)02308-9","title":"Mechanism of action of the calcineurin inhibitors","year":2001,"lang":"en","type":"article","venue":"Transplantation Proceedings","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"NS5A; Pharmacophore; Calcineurin; Mechanism of action; Small molecule; Hepatitis C virus; Biology; Plasma protein binding; Computational biology; Chemistry; Protein–protein interaction; Replicon; Biochemistry; Hepacivirus; Virus; Virology; In vitro; Medicine; Transplantation; DNA","score_opus":0.017013659080705883,"score_gpt":0.25477836603831605,"score_spread":0.23776470695761018,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1965635486","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.51551604,0.3267938,0.05387045,0.010235524,0.0028807488,0.00048428564,0.0008892777,0.0012908268,0.088039115],"genre_scores_gemma":[0.92430484,0.05247719,0.004297908,0.0009360313,0.00034573194,0.00019002288,0.00026797366,0.000040020885,0.017140277],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997713,0.00004630658,0.000009925997,0.00003173007,0.00007420292,0.00006656406],"domain_scores_gemma":[0.9998784,0.000040918698,0.000028887534,0.0000103216435,0.000014457955,0.000027102722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004958381,0.00061580597,0.00047138098,0.00048846344,0.00052820996,0.0012086764,0.0009335166,0.0006739065,0.0024309382],"category_scores_gemma":[0.0003534204,0.00023537762,0.00039109963,0.00022607303,0.0005440559,0.00055415335,0.00031515976,0.001547847,0.0005629221],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019384685,0.00038092726,0.00047532882,0.00086312386,0.00012699646,0.0016085211,0.00019083143,0.0017798849,0.85316306,0.054884344,0.0057618716,0.078826606],"study_design_scores_gemma":[0.00029500938,0.0010276865,0.0029121381,0.00009596184,0.00014018163,0.0022142127,0.00010538353,0.003389862,0.9152808,0.007549068,0.06693743,0.000052150324],"about_ca_topic_score_codex":0.0007349912,"about_ca_topic_score_gemma":0.0009823752,"teacher_disagreement_score":0.0024309382,"about_ca_system_score_codex":0.0010262335,"about_ca_system_score_gemma":0.0006036156,"threshold_uncertainty_score":0.0081323385},"labels":[],"label_agreement":null},{"id":"W1966551688","doi":"10.1002/bies.10105","title":"The role of calcium‐binding proteins in the control of transcription: structure to function","year":2002,"lang":"en","type":"review","venue":"BioEssays","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":139,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Transcription factor; Cell biology; Transcription (linguistics); Transcriptional regulation; Biology; Second messenger system; Calmodulin; DNA-binding protein; Dephosphorylation; Gene; Phosphorylation; Signal transduction; Genetics; Biochemistry; Phosphatase","score_opus":0.02836018581449472,"score_gpt":0.2807312383054828,"score_spread":0.25237105249098807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1966551688","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004822091,0.9971136,0.00058192824,0.00035754617,0.00018144182,0.0000037739667,0.000012075795,0.000015189315,0.0012521504],"genre_scores_gemma":[0.0020019792,0.9963749,0.00041340588,0.00014774034,0.00011541648,0.0000050989743,0.000020538424,0.000001920535,0.0009190241],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99984515,0.000019653822,0.000016825463,0.000044166227,0.00005574568,0.000018364997],"domain_scores_gemma":[0.9998876,0.00004458062,0.000016547896,0.000005955073,0.000029668758,0.000015672536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037041854,0.000931608,0.001397734,0.00085337047,0.00033696822,0.0009443797,0.000970989,0.0010716522,0.0018890296],"category_scores_gemma":[0.00030116225,0.00025123876,0.00025388296,0.0015899243,0.00096103066,0.0012455311,0.0005380748,0.0009930327,0.0022086492],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012939617,0.000052026768,0.00029909884,0.009237289,0.000051550855,0.00042522885,0.00013966933,0.0007082766,0.032884065,0.009115743,0.010312245,0.93664545],"study_design_scores_gemma":[0.000026393449,0.000104802784,0.0019752237,0.0012732877,0.00007075699,0.0017693366,0.00016619501,0.00019472682,0.0058083045,0.008831797,0.97975343,0.000025711184],"about_ca_topic_score_codex":0.0006722128,"about_ca_topic_score_gemma":0.00083209766,"teacher_disagreement_score":0.0018890296,"about_ca_system_score_codex":0.0008607087,"about_ca_system_score_gemma":0.0009292215,"threshold_uncertainty_score":0.0063194036},"labels":[],"label_agreement":null},{"id":"W1968765684","doi":"10.1074/jbc.m200111200","title":"Interactions between Protein Kinase CK2 and Pin1","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institutes of Health","keywords":"PIN1; Phosphorylation; Prolyl isomerase; Cyclin-dependent kinase 1; Peptidylprolyl isomerase; Biology; Kinase; Casein kinase 2; Biochemistry; Cell biology; Chemistry; Isomerase; Protein kinase A; Cyclin-dependent kinase 2; Cell cycle; Enzyme; Cell","score_opus":0.03990813639779084,"score_gpt":0.27085186976172837,"score_spread":0.23094373336393753,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968765684","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888334,0.004639001,0.0024960514,0.00010074317,0.00004882631,0.000021132328,0.00016403884,0.000046217017,0.0036506513],"genre_scores_gemma":[0.9937255,0.0010306363,0.0012775058,0.000069296635,0.000011217568,0.000021853368,0.00048128242,0.000011026617,0.0033716182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998178,0.000024631046,0.000008797879,0.000053925312,0.00004439601,0.00005056793],"domain_scores_gemma":[0.9999275,0.000011117638,0.00002193298,0.0000066214147,0.0000082043025,0.000024538696],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012095432,0.00054503576,0.00019771367,0.00023709326,0.00027304268,0.0005377674,0.00029819348,0.00022057901,0.0023321507],"category_scores_gemma":[0.00018292635,0.00020693387,0.00024254575,0.00015886207,0.00011132257,0.00034438993,0.00038385345,0.0003658522,0.00056514936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019641724,0.000017638482,0.0013586105,0.0000849132,0.000027428869,0.00020763728,0.000018614037,0.00014738832,0.99524623,0.00025988862,0.00011812596,0.0023170393],"study_design_scores_gemma":[0.000029067913,0.00014421638,0.024737364,0.000021334508,0.000056073593,0.0016071508,0.00007131286,0.004289812,0.9591421,0.00012769004,0.009758265,0.000015593589],"about_ca_topic_score_codex":0.00052555127,"about_ca_topic_score_gemma":0.00074770267,"teacher_disagreement_score":0.0023321507,"about_ca_system_score_codex":0.00049541314,"about_ca_system_score_gemma":0.000128249,"threshold_uncertainty_score":0.007801831},"labels":[],"label_agreement":null},{"id":"W1968817880","doi":"10.1074/jbc.m607774200","title":"Calcineurin Increases Cardiac Transient Outward K+ Currents via Transcriptional Up-regulation of Kv4.2 Channel Subunits","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Heart and Stroke Foundation","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; University of Toronto; American Heart Association","keywords":"Calcineurin; Transient (computer programming); Channel (broadcasting); Potassium channel; Cardiac transient outward potassium current; Cell biology; Biophysics; Internal medicine; Chemistry; Biology; Patch clamp; Electrophysiology; Medicine; Computer science; Telecommunications; Transplantation","score_opus":0.02191219342865921,"score_gpt":0.24823206774554604,"score_spread":0.22631987431688683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968817880","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99380857,0.0032549398,0.0013821915,0.000119317985,0.000041117615,0.000016464284,0.00014182014,0.000081290455,0.0011542212],"genre_scores_gemma":[0.99381834,0.0022624438,0.001507781,0.00006229044,0.0000373326,0.000032584438,0.00030518154,0.0000223574,0.001951746],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981207,0.00002555763,0.000022999771,0.00004524747,0.000054786316,0.000039341987],"domain_scores_gemma":[0.9998117,0.00003883056,0.00006419354,0.000020689376,0.000024764682,0.000039743707],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001776074,0.00040416504,0.00028459742,0.00021461623,0.00014837398,0.00032244663,0.0001727502,0.0002144399,0.0009212348],"category_scores_gemma":[0.00021112047,0.00015369247,0.0003719268,0.00013729728,0.00031189926,0.00032707438,0.00022598426,0.0004796508,0.00012479584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006699009,0.000019486804,0.0001844739,0.00002708728,0.0000035449175,0.000028550397,0.000012984763,0.000014482442,0.9991172,0.000027882354,0.000010714979,0.0004865738],"study_design_scores_gemma":[0.000031403055,0.0004385447,0.024550028,0.000010345381,0.000037108457,0.00024864983,0.00007002683,0.0006747279,0.972347,0.00006661481,0.0015190305,0.0000065392214],"about_ca_topic_score_codex":0.0005890973,"about_ca_topic_score_gemma":0.0010938405,"teacher_disagreement_score":0.0009212348,"about_ca_system_score_codex":0.00031174347,"about_ca_system_score_gemma":0.0001972546,"threshold_uncertainty_score":0.0030818582},"labels":[],"label_agreement":null},{"id":"W1968967577","doi":"10.1038/cdd.2013.160","title":"Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation","year":2013,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Associazione Italiana per la Ricerca sul Cancro; Ministero della Salute; McGill University","keywords":"HES1; Neurogenesis; PIN1; Cell biology; Psychological repression; Neural stem cell; Biology; Notch signaling pathway; Signal transduction; Stem cell; Isomerase; Genetics; Gene expression; Gene","score_opus":0.007545292985979336,"score_gpt":0.203911151119072,"score_spread":0.19636585813309265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1968967577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9800064,0.0037898698,0.007334625,0.0004594947,0.00011068258,0.000059744772,0.001263443,0.0006066432,0.0063690636],"genre_scores_gemma":[0.99068296,0.0008194737,0.002718656,0.00015507464,0.000013903749,0.000038831564,0.0007584572,0.000098271455,0.0047144145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997433,0.000024893834,0.000021630694,0.00006310396,0.00006532832,0.000081788305],"domain_scores_gemma":[0.99980575,0.00002085745,0.00006313318,0.000024510544,0.000011310383,0.000074355165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023941987,0.0007190374,0.00041767376,0.00058748556,0.00029248893,0.00076806126,0.00056645036,0.00034832436,0.002240575],"category_scores_gemma":[0.0001781979,0.0004526762,0.0003094719,0.0002935729,0.00055084156,0.0004339892,0.0009221437,0.0010484363,0.0007013231],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019399535,0.00002094135,0.00017908524,0.00004838242,0.000014687306,0.00010276088,0.000005808131,0.000089735004,0.9975994,0.00031154574,0.000101198995,0.001332415],"study_design_scores_gemma":[0.000025242181,0.000043480683,0.0025519764,0.0000032676885,0.000014371181,0.00027097194,0.000017272756,0.00067148154,0.99445564,0.00007406866,0.0018681559,0.000004109817],"about_ca_topic_score_codex":0.0006369757,"about_ca_topic_score_gemma":0.0018054637,"teacher_disagreement_score":0.002240575,"about_ca_system_score_codex":0.00064990844,"about_ca_system_score_gemma":0.00047068732,"threshold_uncertainty_score":0.007495463},"labels":[],"label_agreement":null},{"id":"W196902893","doi":"10.1096/fasebj.20.5.a1117-b","title":"Regulation of vascular smooth muscle cell function by adenylyl cyclase isoforms","year":2006,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Encana (Canada)","funders":"Canadian Institutes of Health Research","keywords":"Adenylyl cyclase; Gene isoform; Forskolin; Gene knockdown; Cell biology; cAMP-dependent pathway; Chemistry; Biology; Signal transduction; Molecular biology; Gene; Receptor; Biochemistry","score_opus":0.0051709887193124,"score_gpt":0.19379151875461295,"score_spread":0.18862053003530055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W196902893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99429566,0.0021792494,0.001700537,0.0000839855,0.000027830378,0.00002050491,0.00022297206,0.000036544858,0.0014327033],"genre_scores_gemma":[0.9955122,0.0014132848,0.0015282257,0.000033419776,0.000010343214,0.000024581877,0.00025020915,0.000009837876,0.0012178165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998528,0.000031394768,0.000012593845,0.000034149267,0.00003381359,0.00003515246],"domain_scores_gemma":[0.999856,0.000029648954,0.000032254306,0.00002007653,0.000021863209,0.000040165145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014835772,0.0002687866,0.00019977998,0.00014572813,0.00016599652,0.00042405393,0.00015865604,0.00018469931,0.00080130476],"category_scores_gemma":[0.00014834074,0.00016642205,0.00023841893,0.00011486314,0.00022856964,0.0002360343,0.00019317651,0.0006330129,0.00021532706],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031020933,0.0000042121787,0.000114419694,0.000009433578,0.0000014764987,0.000010041771,0.000006271712,0.000017503307,0.9995086,0.000040842096,0.0000074079603,0.00024880408],"study_design_scores_gemma":[0.000024446803,0.00024994666,0.020963533,0.000008960302,0.000021141796,0.00017177091,0.000068961584,0.0017747256,0.97450036,0.00008512371,0.0021226103,0.000008424572],"about_ca_topic_score_codex":0.00080589735,"about_ca_topic_score_gemma":0.00081972586,"teacher_disagreement_score":0.00080589735,"about_ca_system_score_codex":0.00032215504,"about_ca_system_score_gemma":0.00015760449,"threshold_uncertainty_score":0.0026805997},"labels":[],"label_agreement":null},{"id":"W1969412514","doi":"10.1006/jmcc.2000.1122","title":"Identification of Genes Regulated During Mechanical Load-induced Cardiac Hypertrophy","year":2000,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Suppression subtractive hybridization; Muscle hypertrophy; Pressure overload; Downregulation and upregulation; Gene; Cardiac hypertrophy; Biology; Calcineurin; Complementary DNA; Gene expression; Internal medicine; Endocrinology; cDNA library; Genetics; Medicine; Transplantation","score_opus":0.006365202623707494,"score_gpt":0.20900612930711326,"score_spread":0.20264092668340578,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969412514","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99063826,0.0015559982,0.0034649766,0.00018349594,0.000047609185,0.00007772664,0.0020297477,0.0000642198,0.0019378824],"genre_scores_gemma":[0.987783,0.00095159217,0.0028769763,0.00019454947,0.000055021774,0.000284308,0.0031880033,0.000030780786,0.0046358462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998368,0.00001669458,0.0000091612665,0.000035339388,0.00003312722,0.000068789894],"domain_scores_gemma":[0.9997563,0.0000648308,0.00005114964,0.000019873338,0.000032950225,0.00007496122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016542296,0.0002657867,0.00037089843,0.00067738397,0.00028044858,0.0003126948,0.00018242226,0.0002651451,0.0018254059],"category_scores_gemma":[0.00023710726,0.00019148004,0.00038290612,0.00038720324,0.00029684132,0.0002087284,0.0003302371,0.00051759207,0.0005265765],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034732893,0.00002597713,0.0006725622,0.00002814576,0.0000039278966,0.00010951517,0.000029823399,0.00002131496,0.99783784,0.00009786683,0.00004204494,0.00078368094],"study_design_scores_gemma":[0.00007386994,0.0006698847,0.2647274,0.000024361834,0.00007083201,0.001059027,0.000363922,0.0012793214,0.7292125,0.00027722676,0.0022207105,0.000020856412],"about_ca_topic_score_codex":0.00044835688,"about_ca_topic_score_gemma":0.00086783385,"teacher_disagreement_score":0.0018254059,"about_ca_system_score_codex":0.000302217,"about_ca_system_score_gemma":0.00021046064,"threshold_uncertainty_score":0.0061065555},"labels":[],"label_agreement":null},{"id":"W1969645554","doi":"10.1074/jbc.c112.345397","title":"STK25 Protein Mediates TrkA and CCM2 Protein-dependent Death in Pediatric Tumor Cells of Neural Origin","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie; Canadian Institutes of Health Research; European Commission; Endocyte","keywords":"Tropomyosin receptor kinase A; Receptor tyrosine kinase; Trk receptor; Cell biology; Low-affinity nerve growth factor receptor; Cancer research; Biology; Tyrosine kinase; Signal transduction; Neurotrophin; Programmed cell death; Kinase; Protein kinase A; Medulloblastoma; Receptor; Apoptosis; Biochemistry","score_opus":0.02233389787543748,"score_gpt":0.257052452397366,"score_spread":0.23471855452192852,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969645554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99782264,0.00041843898,0.000816378,0.000024693974,0.0000061781757,0.000010204545,0.00019705965,0.000021976979,0.0006823888],"genre_scores_gemma":[0.9970835,0.00034990654,0.0006124487,0.00001365041,0.0000027930255,0.000019649506,0.000576083,0.000006001546,0.0013361389],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989414,0.000013081151,0.0000073366996,0.000017913984,0.000029749619,0.000037663136],"domain_scores_gemma":[0.9999366,0.0000086573555,0.000018698729,0.000008661319,0.0000058372207,0.000021518412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007049869,0.00031243527,0.00015982946,0.00016479527,0.0002016903,0.0002229276,0.00017670284,0.00015897572,0.001145468],"category_scores_gemma":[0.00010058721,0.000100455225,0.00024872948,0.00013692114,0.00017183727,0.00013298182,0.00018283846,0.00026402657,0.00043281584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007779781,0.000012590727,0.00042173694,0.000017723423,0.0000066196403,0.00014611051,0.000011936474,0.00007288327,0.99873143,0.00007523578,0.000036404967,0.00038959904],"study_design_scores_gemma":[0.000013244193,0.00015005626,0.012776751,0.0000025710274,0.000012143023,0.00059893046,0.000029324905,0.0009694771,0.9840097,0.000031469495,0.0014028723,0.0000034531488],"about_ca_topic_score_codex":0.002051498,"about_ca_topic_score_gemma":0.003593616,"teacher_disagreement_score":0.002051498,"about_ca_system_score_codex":0.0005513994,"about_ca_system_score_gemma":0.0002807498,"threshold_uncertainty_score":0.004079044},"labels":[],"label_agreement":null},{"id":"W1971016188","doi":"10.1128/jvi.06062-11","title":"Human Coronavirus-Induced Neuronal Programmed Cell Death Is Cyclophilin D Dependent and Potentially Caspase Dispensable","year":2011,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Institute of Infection and Immunity; Canadian Institutes of Health Research","keywords":"Biology; Coronavirus; Programmed cell death; Cell biology; Necroptosis; Caspase; Cyclophilin A; Virology; Cyclophilin; Coronaviridae; Apoptosis; Caspase 8; Cell; Coronavirus disease 2019 (COVID-19); Molecular biology; Genetics; Gene; Disease","score_opus":0.047760050027681536,"score_gpt":0.28313790758691554,"score_spread":0.23537785755923402,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971016188","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9972465,0.0012992739,0.00040907573,0.000032727537,0.000010517837,0.00001298548,0.00015748909,0.000016317743,0.0008151222],"genre_scores_gemma":[0.99802715,0.0007078184,0.00036322806,0.000033995915,0.000005527575,0.000013320318,0.00035538725,0.0000025248985,0.00049109804],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999392,0.000011123144,0.0000064488636,0.000015142212,0.000012818959,0.000015252869],"domain_scores_gemma":[0.9999584,0.0000070148917,0.000011966911,0.000007524388,0.000005965954,0.000009155341],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007086583,0.00014673907,0.00012668097,0.00008036586,0.00010175357,0.00014579277,0.000067451554,0.00011715505,0.00061808067],"category_scores_gemma":[0.00007345897,0.000052579675,0.00017055846,0.00007493471,0.00013499714,0.00008546476,0.00010374958,0.00019022007,0.00013312873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025374405,0.000021523345,0.0005538425,0.00005017996,0.000010018424,0.0001103587,0.0000080166965,0.000026256173,0.99782604,0.00005315392,0.000035297526,0.0010515703],"study_design_scores_gemma":[0.00007164328,0.00075082836,0.034827277,0.000012817362,0.000036130336,0.0013841247,0.000051307503,0.00082200585,0.95857614,0.000085465836,0.003376399,0.0000058996957],"about_ca_topic_score_codex":0.0004239876,"about_ca_topic_score_gemma":0.00063138275,"teacher_disagreement_score":0.00061808067,"about_ca_system_score_codex":0.00020225222,"about_ca_system_score_gemma":0.00014991485,"threshold_uncertainty_score":0.0020676255},"labels":[],"label_agreement":null},{"id":"W1971227627","doi":"10.1016/j.yjmcc.2008.10.020","title":"Increased expression and intramitochondrial translocation of cyclophilin-D associates with increased vulnerability of the permeability transition pore to stress-induced opening during compensated ventricular hypertrophy","year":2008,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Mitochondrial permeability transition pore; Mitochondrion; Cell biology; Cyclophilin; Inner mitochondrial membrane; Biology; Programmed cell death; Chemistry; Biophysics; Biochemistry; Apoptosis","score_opus":0.007525654248571198,"score_gpt":0.20479902034270636,"score_spread":0.19727336609413515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971227627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987128,0.00031183515,0.00068245456,0.00005764086,0.000008362811,0.0000034801722,0.0000637119,0.000015485535,0.0001442404],"genre_scores_gemma":[0.99922454,0.00013091735,0.00021616762,0.000020646567,0.00000985742,0.000010650069,0.00010751093,0.000006600323,0.00027317627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998925,0.00002009937,0.000010864399,0.000022866194,0.000020752548,0.000032953834],"domain_scores_gemma":[0.99964345,0.000037478116,0.00014162692,0.000029928011,0.000022125692,0.00012540404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000116522766,0.00024685953,0.0003280525,0.0004545104,0.00019130322,0.00028471794,0.00016124402,0.0003519083,0.00096263207],"category_scores_gemma":[0.0002974538,0.0002806433,0.00023456705,0.00021269114,0.00049102935,0.00030332655,0.00030117374,0.0006154117,0.00020326837],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010905317,0.000024937666,0.0023512014,0.000020032341,0.000013250245,0.00039582094,0.000031806245,0.00002694623,0.99546933,0.00005546668,0.00003369291,0.00048692402],"study_design_scores_gemma":[0.00010711654,0.0005230238,0.4213888,0.0000115528865,0.00008616557,0.0037478718,0.00028985596,0.0017632009,0.5711107,0.00033689695,0.0006142929,0.000020484063],"about_ca_topic_score_codex":0.00029300636,"about_ca_topic_score_gemma":0.0003122944,"teacher_disagreement_score":0.00096263207,"about_ca_system_score_codex":0.00025484574,"about_ca_system_score_gemma":0.0001181068,"threshold_uncertainty_score":0.0032203794},"labels":[],"label_agreement":null},{"id":"W1971345886","doi":"10.1523/jneurosci.0406-13.2013","title":"CHP1-Mediated NHE1 Biosynthetic Maturation Is Required for Purkinje Cell Axon Homeostasis","year":2013,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health; Howard Hughes Medical Institute","keywords":"Cell biology; Axon; Biology; Neurodegeneration; Purkinje cell; Neuroscience; Gene isoform; Chemistry; Cerebellum; Biochemistry; Gene; Internal medicine","score_opus":0.021512262754130162,"score_gpt":0.2574702174474463,"score_spread":0.23595795469331615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971345886","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916408,0.002501856,0.004040397,0.00015733253,0.000024468332,0.000014890569,0.00048503125,0.0001627641,0.0009724545],"genre_scores_gemma":[0.9951507,0.0010387789,0.0017691395,0.000026355438,0.000009952658,0.0000143350535,0.0005227724,0.000028954124,0.0014389623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989283,0.0000068996997,0.000008102394,0.000036967147,0.00003523274,0.000019858508],"domain_scores_gemma":[0.99985504,0.000011811379,0.000060071812,0.00001328767,0.000017873455,0.00004183526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008581502,0.00039179163,0.00023502688,0.00014938872,0.00027280953,0.00035077002,0.00023948903,0.00034351446,0.0007743668],"category_scores_gemma":[0.000106311716,0.00013455967,0.0001606112,0.00011769812,0.0002695223,0.00028326127,0.00032140192,0.0004864559,0.00042128988],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020595688,0.0000036285242,0.00033295594,0.000022879722,0.0000022040795,0.00009108319,0.000008172437,0.00003920257,0.99874324,0.00007150176,0.000018490822,0.00064600527],"study_design_scores_gemma":[0.000011559727,0.00007322756,0.0378385,0.000008566718,0.000013678249,0.0010232984,0.000039004888,0.0008561936,0.9567997,0.00014099671,0.0031881277,0.000007201211],"about_ca_topic_score_codex":0.00087483187,"about_ca_topic_score_gemma":0.0010865373,"teacher_disagreement_score":0.00087483187,"about_ca_system_score_codex":0.00039593584,"about_ca_system_score_gemma":0.00030242652,"threshold_uncertainty_score":0.002872765},"labels":[],"label_agreement":null},{"id":"W1971899935","doi":"10.1016/j.healun.2009.11.398","title":"384: Egfl7 Prevents Coronary Endothelial ICAM-1 Expression in Response to Calcineurin Inhibition","year":2010,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Medicine; Calcineurin; ICAM-1; Pharmacology; Cardiology; Internal medicine; Immunology; Cell adhesion molecule","score_opus":0.007024358797401099,"score_gpt":0.26662105261191227,"score_spread":0.25959669381451117,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1971899935","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925303,0.0006367504,0.0010693227,0.00089443085,0.00018392039,0.000053604803,0.000671059,0.00016857538,0.0037921001],"genre_scores_gemma":[0.98740095,0.00049922237,0.0012950707,0.0003036354,0.000068187626,0.00011907033,0.0013472236,0.00006233716,0.008904325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963784,0.0000765946,0.000038290123,0.00003673052,0.00007145566,0.00013901922],"domain_scores_gemma":[0.9998436,0.000030152787,0.000021128677,0.000022463279,0.000013082837,0.00006955598],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029300136,0.00048215134,0.00051296764,0.00042582225,0.000445687,0.0005946684,0.00083439273,0.0007917133,0.006048459],"category_scores_gemma":[0.000323925,0.0002878288,0.00041056293,0.0002524309,0.0006827722,0.00040082957,0.00030803983,0.0021191149,0.0017339992],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004259927,0.0011050169,0.00028775315,0.00009966083,0.00004146272,0.00029433946,0.000047329475,0.00025557858,0.9885699,0.00062588905,0.0008549551,0.003558208],"study_design_scores_gemma":[0.00077034644,0.0017533705,0.002928478,0.000015690146,0.00005688182,0.00040748625,0.00010325991,0.0023548917,0.9869006,0.000255426,0.004435397,0.000018170087],"about_ca_topic_score_codex":0.0020779497,"about_ca_topic_score_gemma":0.0028081054,"teacher_disagreement_score":0.006048459,"about_ca_system_score_codex":0.000647596,"about_ca_system_score_gemma":0.0009751493,"threshold_uncertainty_score":0.020234168},"labels":[],"label_agreement":null},{"id":"W1972558420","doi":"10.1093/emboj/20.6.1300","title":"Cyclophilin A regulates HIV‐1 infectivity, as demonstrated by gene targeting in human T cells","year":2001,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":280,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Cypa; Cyclophilin A; Biology; Peptidylprolyl isomerase; Cis-trans-Isomerases; Viral replication; Infectivity; Virology; Group-specific antigen; Cyclophilin; Virus; Gene; Mutation; Molecular biology; Genetics; Isomerase","score_opus":0.007316917003619408,"score_gpt":0.24769242060144947,"score_spread":0.24037550359783005,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972558420","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948833,0.0014762655,0.00094730913,0.00009284763,0.00001676168,0.000012130957,0.0001858525,0.00003973383,0.0023458148],"genre_scores_gemma":[0.9980767,0.0003871866,0.00023016031,0.000022587277,0.000008075269,0.0000082053075,0.00017081224,0.0000067564442,0.0010895217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993074,0.000016200156,0.0000029896455,0.000010441408,0.000011007521,0.000028674045],"domain_scores_gemma":[0.9999298,0.000025096868,0.000009232243,0.0000113721535,0.000006207031,0.000018314131],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007255904,0.00015340609,0.00009099309,0.00020646695,0.00023159101,0.00041022568,0.00010891716,0.0001952669,0.001143315],"category_scores_gemma":[0.0000946063,0.00009957399,0.00017506204,0.00013306667,0.00017498276,0.00008931023,0.000118050266,0.00032665214,0.0003045012],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015628214,0.000015018352,0.00015311796,0.00000766628,0.0000025267352,0.00005191919,0.00001070307,0.00004680374,0.99873227,0.00017375442,0.00004648652,0.0006035183],"study_design_scores_gemma":[0.000020212894,0.00013635332,0.006569238,0.000002446559,0.000012180271,0.00021445272,0.000023741048,0.0012932575,0.99011093,0.0001141761,0.0015003452,0.0000027425021],"about_ca_topic_score_codex":0.0011551984,"about_ca_topic_score_gemma":0.0012245644,"teacher_disagreement_score":0.0011551984,"about_ca_system_score_codex":0.00036844154,"about_ca_system_score_gemma":0.00016750032,"threshold_uncertainty_score":0.0038247705},"labels":[],"label_agreement":null},{"id":"W1972619664","doi":"10.1021/jp505638w","title":"The Influence of Ser-154, Cys-113, and the Phosphorylated Threonine Residue on the Catalytic Reaction Mechanism of Pin1","year":2014,"lang":"en","type":"article","venue":"The Journal of Physical Chemistry B","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Fondo Nacional de Desarrollo Científico y Tecnológico; Vlaamse regering; Universiteit Gent; Natural Sciences and Engineering Research Council of Canada; Fonds Wetenschappelijk Onderzoek; Belgian Federal Science Policy Office","keywords":"Isomerization; Chemistry; Threonine; Serine; PIN1; Residue (chemistry); Prolyl isomerase; Isomerase; Stereochemistry; Peptide; Phosphorylation; Active site; Molecule; Catalysis; Enzyme; Biochemistry; Organic chemistry","score_opus":0.004674253071872721,"score_gpt":0.21549038547653918,"score_spread":0.21081613240466646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972619664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949994,0.00022523748,0.0032050305,0.000061937,0.000020761161,0.0000058526657,0.000032388958,0.000023420867,0.0014259096],"genre_scores_gemma":[0.9979272,0.0002186266,0.0016199746,0.000014915617,0.000002841886,0.0000078115845,0.000037690454,0.000017267404,0.00015365383],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994147,0.000011564094,0.0000032235953,0.000011124146,0.000014827562,0.00001781243],"domain_scores_gemma":[0.99990535,0.000048241203,0.000015141555,0.0000066731996,0.000010351546,0.000014236211],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016906059,0.00034876232,0.00025051425,0.00012799587,0.00029086325,0.0002466452,0.00028047958,0.00019717994,0.0009013098],"category_scores_gemma":[0.0005007188,0.00013615105,0.0003152502,0.00011262671,0.00030129004,0.00029712304,0.00026809867,0.00046197363,0.00010183268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091251114,0.00022350672,0.008970562,0.00046827935,0.000111293426,0.0010982046,0.00022986975,0.45117086,0.51346093,0.008249301,0.00042492506,0.014679791],"study_design_scores_gemma":[0.00006764212,0.00040636552,0.0057557058,0.000022612654,0.00008994774,0.0001393122,0.00015868204,0.8635915,0.12711944,0.0014300464,0.0011737165,0.000045119737],"about_ca_topic_score_codex":0.0018234244,"about_ca_topic_score_gemma":0.0010863567,"teacher_disagreement_score":0.0018234244,"about_ca_system_score_codex":0.00027335554,"about_ca_system_score_gemma":0.00040950638,"threshold_uncertainty_score":0.0036256313},"labels":[],"label_agreement":null},{"id":"W1972729755","doi":"10.1016/s0196-9781(01)00649-0","title":"Drosophila melanogaster flatline encodes a myotropin orthologue to Manduca sexta allatostatin","year":2002,"lang":"en","type":"article","venue":"Peptides","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; National Science Foundation","keywords":"Manduca sexta; Drosophila melanogaster; Melanogaster; Biology; Sphingidae; Gene; In situ hybridization; Peptide; Insect; Cell biology; Biochemistry; Gene expression; Botany","score_opus":0.022853550698456963,"score_gpt":0.24740347815656033,"score_spread":0.22454992745810337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1972729755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98407656,0.0016613742,0.007423411,0.00025074306,0.00015611394,0.00008591751,0.0027037312,0.00040913225,0.003232966],"genre_scores_gemma":[0.96626586,0.00088990934,0.006183475,0.00019418546,0.000028969922,0.000046146142,0.0048775664,0.00013173622,0.021382147],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999294,0.0000071452278,0.000005533755,0.000021731332,0.000019529727,0.000016663134],"domain_scores_gemma":[0.9998573,0.000018876193,0.000046811576,0.0000100116,0.000013527594,0.00005343516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007414642,0.0008343823,0.00022076564,0.00036592752,0.00034086162,0.00025218097,0.00027079575,0.00039607706,0.0018108779],"category_scores_gemma":[0.00008306418,0.0002943161,0.00029866977,0.00013318409,0.0002566587,0.00022714559,0.00030099862,0.0005696122,0.00096415024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058745045,0.000005817068,0.00014820875,0.000015951684,0.0000030411795,0.00020011798,0.0000064628393,0.000027476588,0.9987764,0.0000832323,0.000075417614,0.00059922144],"study_design_scores_gemma":[0.000056041423,0.00020718873,0.031852715,0.000017198388,0.000048002472,0.0017852382,0.00011528755,0.00132146,0.9488417,0.00012011204,0.015610063,0.000025081232],"about_ca_topic_score_codex":0.0022509615,"about_ca_topic_score_gemma":0.005761276,"teacher_disagreement_score":0.0022509615,"about_ca_system_score_codex":0.0006476152,"about_ca_system_score_gemma":0.00022609503,"threshold_uncertainty_score":0.0060579777},"labels":[],"label_agreement":null},{"id":"W1973283904","doi":"10.1046/j.0022-3042.2002.00783.x","title":"FKHRL1 and its homologs are new targets of nerve growth factor Trk receptor signaling","year":2002,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Canadian Institutes of Health Research; Alzheimer Society; McGill University","keywords":"Tropomyosin receptor kinase A; Trk receptor; Neurotrophin; Protein kinase B; Low-affinity nerve growth factor receptor; Biology; Cell biology; Nerve growth factor; Phosphorylation; Tropomyosin receptor kinase B; Cancer research; Neurotrophic factors; Kinase; Tropomyosin receptor kinase C; Signal transduction; Receptor; Growth factor; Biochemistry; Platelet-derived growth factor receptor","score_opus":0.021947833059616735,"score_gpt":0.2310724256425724,"score_spread":0.20912459258295568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973283904","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95898926,0.031936474,0.004125446,0.0004964692,0.00008553863,0.000018156523,0.00049680227,0.00020247852,0.0036494776],"genre_scores_gemma":[0.985436,0.0057176887,0.002428808,0.0000840677,0.00008027728,0.00001654285,0.00088289345,0.000010398757,0.0053434246],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991953,0.0000060882785,0.0000040404684,0.000020278088,0.000024512467,0.000025427702],"domain_scores_gemma":[0.9999498,0.000007499021,0.000019815427,0.0000041774097,0.00000810822,0.00001067089],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009273541,0.00023358643,0.00019777645,0.00019361668,0.00018522929,0.00030373145,0.000169991,0.00020906501,0.001236687],"category_scores_gemma":[0.000103894134,0.00008328221,0.00013975064,0.000097539174,0.00012228858,0.0003091661,0.00014351691,0.00025994543,0.00042492835],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003349537,0.000021501397,0.0009921757,0.000107189,0.000009284148,0.0005793329,0.00004742044,0.00014659944,0.9779424,0.00062197517,0.00035876286,0.01883836],"study_design_scores_gemma":[0.00006290506,0.0006464666,0.048883498,0.000026013726,0.00009280607,0.0057574837,0.00008976417,0.0015624954,0.8946388,0.0007352324,0.047472738,0.0000318128],"about_ca_topic_score_codex":0.0005644842,"about_ca_topic_score_gemma":0.0013551422,"teacher_disagreement_score":0.001236687,"about_ca_system_score_codex":0.00048118853,"about_ca_system_score_gemma":0.000110535046,"threshold_uncertainty_score":0.004137099},"labels":[],"label_agreement":null},{"id":"W1973448683","doi":"10.1002/mc.20136","title":"NFATc3 deficiency may contribute to the development of mammary gland adenocarcinoma in aging female mice","year":2005,"lang":"en","type":"article","venue":"Molecular Carcinogenesis","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University; Sudbury Regional Hospital; Northeast Cancer Centre","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Biology; NFAT; Mammary gland; Suppressor; Internal medicine; Endocrinology; Adenocarcinoma; Transcription factor; Cancer research; Cancer; Breast cancer; Gene; Genetics","score_opus":0.01294253080947274,"score_gpt":0.244209425840617,"score_spread":0.23126689503114425,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1973448683","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99448144,0.0013901129,0.0024833821,0.00010440239,0.000024056693,0.000014980581,0.00028166553,0.000113223796,0.0011066423],"genre_scores_gemma":[0.9932239,0.0011068282,0.0013184441,0.000050512434,0.000020008572,0.000028694732,0.00031174807,0.00003697775,0.0039030435],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999155,0.000013931766,0.000009735303,0.000025320398,0.000016432563,0.000019016714],"domain_scores_gemma":[0.9997683,0.000019353127,0.00009651405,0.000024197641,0.000018341741,0.000073191],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016501838,0.00047962036,0.00024531217,0.0004156116,0.00021650668,0.00022110017,0.00014745229,0.00026061942,0.0015655182],"category_scores_gemma":[0.00017461593,0.00017884525,0.00023233987,0.00012667154,0.00018004345,0.00021315992,0.00019607363,0.00044191632,0.00034109727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023618904,0.000027439917,0.0035991885,0.000018298424,0.0000061581486,0.00023410037,0.000023576447,0.00002063667,0.9934088,0.00009888744,0.000039775565,0.0022871157],"study_design_scores_gemma":[0.000063475985,0.0009466427,0.14064401,0.000016872575,0.000097898315,0.007436778,0.0001214815,0.00077916397,0.84325737,0.00031129472,0.006305931,0.00001916711],"about_ca_topic_score_codex":0.0004033389,"about_ca_topic_score_gemma":0.0006943898,"teacher_disagreement_score":0.0015655182,"about_ca_system_score_codex":0.00015818623,"about_ca_system_score_gemma":0.00014700781,"threshold_uncertainty_score":0.005237162},"labels":[],"label_agreement":null},{"id":"W1975535949","doi":"10.1007/s11010-010-0635-y","title":"The precursor to the germ cell-specific PCSK4 proteinase is inefficiently activated in transfected somatic cells: evidence of interaction with the BiP chaperone","year":2010,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Endoplasmic reticulum; Prohormone convertase; Proprotein convertase; HEK 293 cells; Biology; Somatic cell; Transfection; Cell biology; Zymogen; Kexin; Protein disulfide-isomerase; Biochemistry; Subtilisin; Furin; Chemistry; Molecular biology; Enzyme; Gene; LDL receptor; Prohormone","score_opus":0.006203169433544104,"score_gpt":0.2171617205270368,"score_spread":0.2109585510934927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1975535949","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9800079,0.0013712131,0.014176663,0.0003248636,0.00011948488,0.00004227291,0.0014273117,0.00038331584,0.0021468888],"genre_scores_gemma":[0.9818081,0.00075418735,0.005489317,0.00012925452,0.000028163142,0.000051149415,0.0024031254,0.00032351975,0.00901313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994406,0.00007668327,0.000086642554,0.00012589405,0.00017959431,0.0000905989],"domain_scores_gemma":[0.99909544,0.00023834528,0.00020195621,0.000155409,0.000088047585,0.0002208108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00039010932,0.00045369985,0.00049489515,0.0005365829,0.00036806014,0.0013141012,0.000530852,0.00057797384,0.0026767612],"category_scores_gemma":[0.00031753452,0.00047073173,0.00046215378,0.00034638733,0.0005496361,0.00041802687,0.0004128776,0.0017078926,0.0020231495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034342953,0.000006726207,0.00006243515,0.000012759997,0.000004579182,0.00004235486,0.0000089203,0.00001172879,0.9995358,0.00008108053,0.000016138734,0.00018325947],"study_design_scores_gemma":[0.000009952047,0.000033076318,0.0014920158,0.0000022373542,0.000012122403,0.00029796574,0.000018758901,0.00040950472,0.99646086,0.000036079156,0.0012231495,0.00000424875],"about_ca_topic_score_codex":0.0012172473,"about_ca_topic_score_gemma":0.0011526034,"teacher_disagreement_score":0.0026767612,"about_ca_system_score_codex":0.0005883987,"about_ca_system_score_gemma":0.00047915606,"threshold_uncertainty_score":0.008954644},"labels":[],"label_agreement":null},{"id":"W1976449858","doi":"10.1097/00007890-200007270-00017","title":"IMMUNOPHILINS MAY LIMIT CALCINEURIN INHIBITION BY CYCLOSPORINE AND TACROLIMUS AT HIGH DRUG CONCENTRATIONS1","year":2000,"lang":"en","type":"article","venue":"Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Calcineurin; Phosphatase; Dephosphorylation; Potency; Pharmacology; Tacrolimus; Chemistry; IC50; In vivo; Biochemistry; In vitro; Biology; Transplantation; Enzyme; Internal medicine; Medicine","score_opus":0.0036214131771488377,"score_gpt":0.20782974405775742,"score_spread":0.20420833088060858,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976449858","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98206156,0.009120849,0.004287208,0.0001466998,0.0000419981,0.00003877353,0.00013779526,0.0000955151,0.0040695276],"genre_scores_gemma":[0.9962936,0.0011950278,0.0015070628,0.00005576848,0.000032412012,0.00001653714,0.000099141886,0.000008911467,0.0007914278],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981076,0.00004007384,0.00001928155,0.000025540588,0.00005651457,0.000047816502],"domain_scores_gemma":[0.9997813,0.00007318728,0.00006259269,0.000014294233,0.000031488984,0.000037195456],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021753427,0.0002597455,0.00024406053,0.00017540473,0.00015981498,0.00045204064,0.00017117936,0.00033649296,0.001227654],"category_scores_gemma":[0.00037045422,0.000101845886,0.00021332827,0.0001083712,0.0002245388,0.00019660249,0.00015747335,0.00036660774,0.00028640646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011195106,0.000021558963,0.0006883713,0.00005855652,0.000009199079,0.000043389122,0.000007835799,0.000091687434,0.9948954,0.000113734866,0.000055614953,0.0039025715],"study_design_scores_gemma":[0.000013009777,0.00055590784,0.01608263,0.000009457415,0.00005132029,0.00051520637,0.000015694866,0.0012517031,0.978336,0.00007082612,0.003093742,0.000004445361],"about_ca_topic_score_codex":0.00036587767,"about_ca_topic_score_gemma":0.00072351145,"teacher_disagreement_score":0.001227654,"about_ca_system_score_codex":0.00025811122,"about_ca_system_score_gemma":0.00020711901,"threshold_uncertainty_score":0.0041068792},"labels":[],"label_agreement":null},{"id":"W1976807738","doi":"10.1523/jneurosci.2404-07.2007","title":"The Inhibition Site on Myelin-Associated Glycoprotein Is within Ig-Domain 5 and Is Distinct from the Sialic Acid Binding Site","year":2007,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health","keywords":"Chinese hamster ovary cell; Myelin-associated glycoprotein; Sialic acid; Neurite; Glycoprotein; Ganglioside; Binding site; SIGLEC; Molecular biology; Chemistry; Glycan; Biology; Biochemistry; Myelin; Receptor; In vitro; Central nervous system","score_opus":0.014975268980523804,"score_gpt":0.256409483142247,"score_spread":0.24143421416172317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1976807738","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99063134,0.0013899327,0.0051616216,0.000047530866,0.000025145971,0.000028763894,0.00016469765,0.000042914766,0.0025080077],"genre_scores_gemma":[0.9935615,0.0004043635,0.0039777337,0.00007172177,0.0000059035638,0.000019839374,0.0004891371,0.000012084273,0.001457682],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985254,0.000013212388,0.000009694649,0.000035819256,0.00004578924,0.000043036136],"domain_scores_gemma":[0.9998895,0.000018092218,0.00003925396,0.000016467466,0.000009539677,0.00002719312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008722998,0.000406784,0.00035509383,0.00016094864,0.00016581175,0.00028220296,0.00036922639,0.00043360342,0.0010247232],"category_scores_gemma":[0.00010313526,0.00014481653,0.00070109015,0.00010970707,0.0004013391,0.00025047842,0.0002968532,0.0007642166,0.00057149545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003832944,0.000009689777,0.00014987403,0.000021024423,0.0000041644735,0.000041774274,0.000006183964,0.000046447454,0.9990232,0.00013076361,0.0000065447553,0.0005219773],"study_design_scores_gemma":[0.000007765674,0.0001885528,0.0063451054,0.000007636286,0.000018543273,0.00046378258,0.000013180134,0.0004372954,0.9903645,0.000050874387,0.0020978013,0.0000049066043],"about_ca_topic_score_codex":0.0010333665,"about_ca_topic_score_gemma":0.0010680992,"teacher_disagreement_score":0.0010333665,"about_ca_system_score_codex":0.00058228057,"about_ca_system_score_gemma":0.00044174347,"threshold_uncertainty_score":0.0042247176},"labels":[],"label_agreement":null},{"id":"W1978477818","doi":"10.1016/j.bbrc.2014.03.068","title":"Basic Tilted Helix Bundle – A new protein fold in human FKBP25/FKBP3 and HectD1","year":2014,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto; University Health Network","funders":"Canadian Institutes of Health Research; National Institute of General Medical Sciences; Wellcome Trust","keywords":"Helix bundle; FKBP; Ubiquitin ligase; Bundle; Conserved sequence; Protein structure; Biology; Sequence motif; Peptide sequence; Biophysics; DNA; Crystallography; Chemistry; Ubiquitin; Cell biology; Genetics; Biochemistry; Gene; Materials science","score_opus":0.06632566146860812,"score_gpt":0.36970825152358866,"score_spread":0.3033825900549805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1978477818","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911141,0.0011660608,0.0058862595,0.00019896074,0.00010270778,0.000022491315,0.00018342097,0.00015912167,0.0011669399],"genre_scores_gemma":[0.99655044,0.00013276513,0.0018167665,0.00011602498,0.000021126454,0.000010053317,0.0003112214,0.000011391118,0.0010300871],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999232,0.000010934409,0.0000069627786,0.000022687866,0.000019206193,0.000017002669],"domain_scores_gemma":[0.9998621,0.000007909992,0.000041448595,0.000010434231,0.000012537722,0.000065582804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001232249,0.0002948278,0.00035863815,0.00014890065,0.00038444853,0.0002976904,0.00032498562,0.00039218494,0.0010535567],"category_scores_gemma":[0.00016942013,0.00017156466,0.00034065693,0.00024169506,0.00030549424,0.00037473702,0.00034003684,0.00045244864,0.0003878828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009409084,0.00006487316,0.0025917497,0.00013275142,0.00005035731,0.0025443018,0.00014707155,0.0012612534,0.9840979,0.001527835,0.00093022856,0.0057108123],"study_design_scores_gemma":[0.00028120747,0.0017857588,0.12122645,0.000060267867,0.00027237323,0.01605462,0.00072662026,0.024921976,0.79483986,0.003450625,0.036202975,0.00017717022],"about_ca_topic_score_codex":0.00062323443,"about_ca_topic_score_gemma":0.0005609521,"teacher_disagreement_score":0.0010535567,"about_ca_system_score_codex":0.00042943028,"about_ca_system_score_gemma":0.00016267637,"threshold_uncertainty_score":0.0035244226},"labels":[],"label_agreement":null},{"id":"W1979623506","doi":"10.1016/j.matbio.2015.01.018","title":"EMMPRIN, an upstream regulator of MMPs, in CNS biology","year":2015,"lang":"en","type":"review","venue":"Matrix Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Regulator; Metalloproteinase; Neuroscience; Homeostasis; Central nervous system; Integrin; Multiple sclerosis; Cell adhesion molecule; Extracellular matrix; Medicine; Immunology; Biology; Cell biology; Receptor; Internal medicine","score_opus":0.05639088614204475,"score_gpt":0.4075042400504199,"score_spread":0.35111335390837517,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979623506","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00042434095,0.99682826,0.00025912604,0.00026183072,0.0001565402,0.000003772455,0.000021905134,0.000013176131,0.002031052],"genre_scores_gemma":[0.001601099,0.99679583,0.00026091214,0.000104948485,0.000086050444,0.0000042480024,0.000027947333,0.0000016807369,0.0011173029],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99992263,0.000010508905,0.000010666551,0.000015259513,0.000030898733,0.000010123805],"domain_scores_gemma":[0.9999045,0.000035903882,0.000013941821,0.0000035257908,0.000028662193,0.00001349854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023895805,0.0005356087,0.00057530444,0.0011244082,0.00022091452,0.00066637166,0.0003928214,0.0006401919,0.0025833873],"category_scores_gemma":[0.00028784855,0.00015233952,0.00026209035,0.0012391584,0.00027859243,0.0009145178,0.00047654082,0.00096256,0.0014255667],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007962222,0.000052783143,0.00025820787,0.0104929935,0.000052644293,0.00026228503,0.00008495131,0.0003691579,0.0072056036,0.005348016,0.017356306,0.95843744],"study_design_scores_gemma":[0.000007479271,0.00007051932,0.0011802851,0.0015665762,0.00006829775,0.00131158,0.00006654311,0.000091236856,0.0017342021,0.0022476267,0.99164283,0.000012903587],"about_ca_topic_score_codex":0.0005064068,"about_ca_topic_score_gemma":0.0009156095,"teacher_disagreement_score":0.0025833873,"about_ca_system_score_codex":0.00043629008,"about_ca_system_score_gemma":0.00071432715,"threshold_uncertainty_score":0.008642256},"labels":[],"label_agreement":null},{"id":"W1979737692","doi":"10.1107/s0907444900005096","title":"Crystallization and preliminary X-ray analysis of human grancalcin, a novel cytosolic Ca<sup>2+</sup>-binding protein present in leukocytes","year":2000,"lang":"en","type":"article","venue":"Acta Crystallographica Section D Biological Crystallography","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute; ProteinQure (Canada)","funders":"","keywords":"Crystallization; Crystallography; Recombinant DNA; X-ray crystallography; Chemistry; Crystal (programming language); Cytosol; Space group; Group (periodic table); Diffraction; Biochemistry; Physics; Enzyme; Optics","score_opus":0.01727764717087375,"score_gpt":0.24914643611652168,"score_spread":0.23186878894564794,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1979737692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9774137,0.0061384374,0.0068831802,0.0007889159,0.00008306022,0.00015663714,0.00576149,0.00012497936,0.0026495578],"genre_scores_gemma":[0.90796983,0.008132303,0.035335597,0.00025580035,0.00006877101,0.00018512354,0.03722033,0.00014055656,0.010691807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998497,0.000023713292,0.00001504818,0.000032881537,0.000052199528,0.000026504897],"domain_scores_gemma":[0.99987257,0.000024044606,0.000017018452,0.00002031422,0.000038979742,0.000027054788],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021772186,0.00039729755,0.0004172183,0.00014865297,0.00045798032,0.0005723695,0.00047566928,0.00045496624,0.00067537796],"category_scores_gemma":[0.00042043952,0.00017142878,0.00027801824,0.0007364503,0.00025748153,0.00022677596,0.00018729617,0.0007027541,0.00038552334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009816822,0.00019190797,0.0020477963,0.00025075793,0.00004227906,0.0005379827,0.00025038805,0.0019137986,0.9816735,0.0010103792,0.0018662788,0.009233285],"study_design_scores_gemma":[0.00023852693,0.0002804264,0.015543746,0.000023657625,0.000053125954,0.0016030475,0.00020458267,0.004025707,0.92508876,0.00048481228,0.052424535,0.000029001414],"about_ca_topic_score_codex":0.004529079,"about_ca_topic_score_gemma":0.003847084,"teacher_disagreement_score":0.004529079,"about_ca_system_score_codex":0.0007603354,"about_ca_system_score_gemma":0.0005738654,"threshold_uncertainty_score":0.009005427},"labels":[],"label_agreement":null},{"id":"W1980974663","doi":"10.1371/journal.pone.0013559","title":"Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Karolinska Institutet; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; Canadian Institutes of Health Research; Ontario Genomics; Genome Canada; Knut och Alice Wallenbergs Stiftelse; Canadian Light Source; Ontario Innovation Trust; Wellcome Trust; GlaxoSmithKline","keywords":"Fragile X syndrome; FMR1; Biology; Heterogeneous nuclear ribonucleoprotein; Tandem repeat; Genetics; Gene; Ribonucleoprotein; Histone; Trinucleotide repeat expansion; Cell biology; Genome; Fragile x; RNA","score_opus":0.026501829274557746,"score_gpt":0.2475404433639281,"score_spread":0.22103861408937037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980974663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946613,0.0025107143,0.0012165128,0.00015241282,0.000022815697,0.000018230741,0.00038380417,0.00004404128,0.0009902822],"genre_scores_gemma":[0.99258244,0.0014347429,0.0026275103,0.000075704476,0.000015252547,0.000022647022,0.0021923447,0.000013150174,0.0010361208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992883,0.000009809375,0.0000039657884,0.000016965123,0.00002535962,0.000015052443],"domain_scores_gemma":[0.99988616,0.000024431112,0.00003989633,0.000004991145,0.000018624534,0.00002584454],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001871944,0.0004606977,0.00023752157,0.00014304105,0.00026888784,0.00020136268,0.00057252886,0.00029304522,0.0010367794],"category_scores_gemma":[0.0003337971,0.00014645838,0.0002870133,0.00020995033,0.00018319985,0.00022008555,0.0002372416,0.00068254414,0.00017183433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010108749,0.00026395934,0.008395853,0.000830655,0.0001571123,0.0015359544,0.00040683453,0.011756244,0.95789486,0.0028414875,0.0019665363,0.0129395425],"study_design_scores_gemma":[0.0006967588,0.0018520643,0.13922112,0.00024001779,0.00050217705,0.0052227913,0.0015647514,0.1201434,0.689312,0.0019493139,0.039149944,0.00014566231],"about_ca_topic_score_codex":0.0029039818,"about_ca_topic_score_gemma":0.0028401115,"teacher_disagreement_score":0.0029039818,"about_ca_system_score_codex":0.00060378015,"about_ca_system_score_gemma":0.0003709932,"threshold_uncertainty_score":0.0057742},"labels":[],"label_agreement":null},{"id":"W1981328947","doi":"10.1371/journal.pone.0122852","title":"Secoisolariciresinol Diglucoside Abrogates Oxidative Stress-Induced Damage in Cardiac Iron Overload Condition","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; NOSM University; Lakehead University","funders":"","keywords":"Oxidative stress; Inflammation; Superoxide dismutase; Apoptosis; Tumor necrosis factor alpha; Endocrinology; ASK1; Internal medicine; Pressure overload; Chemistry; Protein kinase A; Kinase; Medicine; Biochemistry; Heart failure; Cyclin-dependent kinase 2","score_opus":0.04036838340530347,"score_gpt":0.25603705819368827,"score_spread":0.2156686747883848,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1981328947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950884,0.0023571905,0.0009806525,0.00010972182,0.00005359443,0.000033674525,0.00023558218,0.00007184029,0.0010693127],"genre_scores_gemma":[0.99525934,0.0013816514,0.0012435348,0.00007595166,0.00001861849,0.000027942522,0.0004415564,0.000012445799,0.0015389691],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999554,0.000010644604,0.000005089813,0.000007752205,0.000007697087,0.000013315771],"domain_scores_gemma":[0.9999496,0.000007506518,0.000014090731,0.0000053567833,0.0000066636558,0.000016860233],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000077195036,0.00037258354,0.00030964485,0.00020898548,0.00009235171,0.000119352495,0.00014121085,0.00028859737,0.0009984158],"category_scores_gemma":[0.000060448612,0.00008016968,0.000192791,0.00009363413,0.000121381134,0.00013200674,0.00009840577,0.00037760174,0.00015605793],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00059915654,0.00011180255,0.00008817443,0.00007412268,0.000008137597,0.000071776565,0.000009097507,0.000040221974,0.9967301,0.000024334517,0.00003769935,0.0022054387],"study_design_scores_gemma":[0.000071446826,0.0022821727,0.0037965921,0.000010299825,0.00002276344,0.0001716428,0.000022784896,0.00032710322,0.9913662,0.00002582271,0.0018985316,0.0000045077386],"about_ca_topic_score_codex":0.0003131208,"about_ca_topic_score_gemma":0.00061324827,"teacher_disagreement_score":0.0009984158,"about_ca_system_score_codex":0.00008782651,"about_ca_system_score_gemma":0.00011183551,"threshold_uncertainty_score":0.0033400059},"labels":[],"label_agreement":null},{"id":"W1982070989","doi":"10.1016/j.mce.2007.05.003","title":"Cardiac BNP gene activation by angiotensin II in vivo","year":2007,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Angiotensin II; Luciferase; In vivo; Genetically modified mouse; Transgene; Internal medicine; Endocrinology; Natriuretic peptide; Renin–angiotensin system; Reporter gene; Receptor; Chemistry; Gene expression; Biology; Gene; Medicine; Heart failure; Transfection; Biochemistry","score_opus":0.00557472482076236,"score_gpt":0.21865092489991275,"score_spread":0.2130762000791504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982070989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97943044,0.002211028,0.011157484,0.0005832457,0.00035481594,0.000054764972,0.0008947963,0.00026847539,0.0050450084],"genre_scores_gemma":[0.9830981,0.0010505856,0.0039799353,0.0002654506,0.00013068273,0.00008227544,0.0013501183,0.00019291951,0.0098498985],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994825,0.0001244545,0.00003320963,0.00011918999,0.000097716395,0.0001429043],"domain_scores_gemma":[0.9992811,0.00029456025,0.00007031302,0.000085641026,0.000027404487,0.00024101729],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000492736,0.00057976367,0.0004789999,0.0006639599,0.00030141074,0.0008426516,0.0004247135,0.00045937378,0.0028309207],"category_scores_gemma":[0.0003638302,0.00047382247,0.00044116817,0.0002783551,0.00080660265,0.0005570772,0.00038805406,0.0020547123,0.0008457458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003582974,0.00004168855,0.00006866859,0.000015893467,0.0000039892534,0.000059801463,0.000016420063,0.000050040955,0.9985374,0.00026380533,0.000052847132,0.0005309993],"study_design_scores_gemma":[0.00006897297,0.00028435283,0.0020084095,0.0000052390137,0.000014422445,0.00026854646,0.000051967494,0.0010577138,0.9947125,0.00022698122,0.0012916914,0.00000915587],"about_ca_topic_score_codex":0.0012904955,"about_ca_topic_score_gemma":0.0021038214,"teacher_disagreement_score":0.0028309207,"about_ca_system_score_codex":0.00068547897,"about_ca_system_score_gemma":0.00033748633,"threshold_uncertainty_score":0.009470403},"labels":[],"label_agreement":null},{"id":"W1982552108","doi":"10.1023/b:nere.0000042218.27842.79","title":"In vitro Proteolytic Degradation of Bovine Brain Calcineurin by m-Calpain","year":2004,"lang":"en","type":"article","venue":"Neurochemical Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"Saskatchewan Health Research Foundation; Heart and Stroke Foundation of Canada","keywords":"Calpain; Proteolysis; Biochemistry; Protein subunit; Dephosphorylation; Phosphatase; Calmodulin; Protease; Cell biology; Biology; Calcineurin; Phosphorylation; Cysteine protease; Chemistry; Molecular biology; Enzyme; Internal medicine","score_opus":0.03305398205359606,"score_gpt":0.35347245538614364,"score_spread":0.3204184733325476,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982552108","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9610233,0.021893911,0.011042595,0.00044984056,0.00037070975,0.00012434002,0.0010381802,0.00012350589,0.003933581],"genre_scores_gemma":[0.9769795,0.0064611817,0.007768546,0.00016483327,0.00014157871,0.00007886583,0.0035751245,0.000051344236,0.0047789225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99953103,0.00010476271,0.00007298441,0.00008064105,0.00007826202,0.00013227772],"domain_scores_gemma":[0.999371,0.0002640359,0.00010592872,0.00010638267,0.000090681366,0.000062060506],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008669317,0.0007679841,0.000429913,0.00045512998,0.00039256574,0.00050889474,0.0007572172,0.00046189944,0.0017427199],"category_scores_gemma":[0.0008850035,0.00029568438,0.0006619447,0.00053319073,0.00032570495,0.0004433467,0.00028433788,0.0012552566,0.00061602524],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015908006,0.0002243903,0.00039923046,0.00024417575,0.000053480202,0.00023237057,0.00008391653,0.00030417825,0.9926523,0.00050563616,0.00023231519,0.0034771988],"study_design_scores_gemma":[0.000091621696,0.00036820004,0.0022040622,0.000025564155,0.000043432545,0.00047523982,0.000030215384,0.0013058332,0.99208224,0.00011732761,0.0032461605,0.000010143962],"about_ca_topic_score_codex":0.0040553277,"about_ca_topic_score_gemma":0.0043748016,"teacher_disagreement_score":0.0040553277,"about_ca_system_score_codex":0.0012945455,"about_ca_system_score_gemma":0.00054198294,"threshold_uncertainty_score":0.0093925595},"labels":[],"label_agreement":null},{"id":"W1982926678","doi":"10.1016/j.transproceed.2004.01.017","title":"Neoral C2 monitoring in solid organ transplantation","year":2004,"lang":"en","type":"review","venue":"Transplantation Proceedings","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"CXCR3; Chemokine; Transplantation; Blockade; Immunology; Receptor; Chemokine receptor; Heart transplantation; CXCL10; Medicine; Biology; Pharmacology; Internal medicine","score_opus":0.030055021311995514,"score_gpt":0.3284431687750765,"score_spread":0.298388147463081,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1982926678","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002133579,0.9963883,0.0007658656,0.00056195864,0.0004955079,0.000005348151,0.0000108544555,0.0000115852035,0.0015471396],"genre_scores_gemma":[0.0034861933,0.99116606,0.0012580337,0.0007481509,0.00091346016,0.000018496457,0.00004012727,0.000004933369,0.0023644664],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997002,0.00007018517,0.00003433671,0.000050272385,0.000118793534,0.00002626523],"domain_scores_gemma":[0.9993882,0.00035729882,0.000058914262,0.000019673975,0.0001299181,0.00004598068],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013625596,0.0011086077,0.0017049367,0.0014807732,0.00030440165,0.0013764978,0.0012764679,0.0019114264,0.0021086622],"category_scores_gemma":[0.0011799026,0.00027958787,0.00049791066,0.0014729762,0.0009940261,0.0010706052,0.00047038347,0.002533431,0.0017167479],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026716123,0.00008795073,0.00034034654,0.0032516555,0.00008229901,0.000782821,0.000028868686,0.0005575634,0.0021832413,0.0031373561,0.024451122,0.9648296],"study_design_scores_gemma":[0.00009585774,0.0002063299,0.0014824419,0.0016561777,0.00019602048,0.004951027,0.000063419386,0.00045980833,0.003319977,0.0028602243,0.98467505,0.000033734184],"about_ca_topic_score_codex":0.0016939573,"about_ca_topic_score_gemma":0.0033237499,"teacher_disagreement_score":0.0021086622,"about_ca_system_score_codex":0.0010704829,"about_ca_system_score_gemma":0.0011060492,"threshold_uncertainty_score":0.007766962},"labels":[],"label_agreement":null},{"id":"W1983020854","doi":"10.1016/j.neuron.2007.12.003","title":"A Crystal-Clear Interaction: Relating Neuroligin/Neurexin Complex Structure to Function at the Synapse","year":2007,"lang":"en","type":"letter","venue":"Neuron","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Neuroligin; Neurexin; Neuroscience; Synapse; Biology; Function (biology); NLS; Biological neural network; Cell biology; Receptor; Genetics; Postsynaptic potential; Nuclear localization sequence; Excitatory postsynaptic potential; Nucleus; Inhibitory postsynaptic potential","score_opus":0.022764779668682993,"score_gpt":0.26464691264181556,"score_spread":0.24188213297313257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983020854","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.025222916,0.0066500395,0.004282927,0.9084532,0.046197698,0.000054577376,0.0003236876,0.00025002728,0.00856484],"genre_scores_gemma":[0.3339295,0.014478721,0.008551687,0.5131294,0.07965235,0.0002584334,0.00075282075,0.0001821651,0.04906487],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995579,0.000089255904,0.00004602982,0.000064337924,0.00016589845,0.00007659761],"domain_scores_gemma":[0.9990527,0.00049165287,0.00008938699,0.000055322344,0.00012227707,0.00018854217],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008329362,0.00063525507,0.001099029,0.00026509629,0.0015194279,0.0014645006,0.0014749019,0.012391141,0.005163678],"category_scores_gemma":[0.0037637916,0.00046632992,0.00064271066,0.00028810446,0.0015597474,0.0014768844,0.0008243616,0.0108048385,0.0020874746],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0017189017,0.00024285738,0.001555535,0.00036715722,0.00012071437,0.019612996,0.00023077018,0.0009520741,0.016230479,0.019463418,0.90517205,0.034332976],"study_design_scores_gemma":[0.0032803696,0.00091225444,0.005687026,0.00021898282,0.00036808042,0.040094994,0.0009517576,0.018513747,0.051963914,0.10840729,0.7693476,0.00025394897],"about_ca_topic_score_codex":0.0010269891,"about_ca_topic_score_gemma":0.001402107,"teacher_disagreement_score":0.012391141,"about_ca_system_score_codex":0.0018597319,"about_ca_system_score_gemma":0.00073542143,"threshold_uncertainty_score":0.0172742},"labels":[],"label_agreement":null},{"id":"W1983180509","doi":"10.1139/o04-055","title":"Complex expression pattern of the Barth syndrome gene product tafazzin in human cell lines and murine tissues","year":2004,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Danmarks Tekniske Universitet; Yale University; Barth Syndrome Foundation","keywords":"Biology; Molecular biology; Exon; Alternative splicing; Cardiolipin; Complementary DNA; Gene; Genetics","score_opus":0.011864245864174556,"score_gpt":0.24057439778290843,"score_spread":0.22871015191873387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983180509","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98698205,0.004125385,0.005005245,0.000086204556,0.000021048794,0.000033386026,0.001273391,0.0001241471,0.0023491012],"genre_scores_gemma":[0.9852763,0.0018758918,0.0048959344,0.000063658146,0.000013855075,0.000042063948,0.0037454201,0.000034631234,0.0040522274],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998485,0.000018917803,0.000015747584,0.000055860604,0.000037814483,0.000023253766],"domain_scores_gemma":[0.9998394,0.000056272558,0.000023443577,0.000031240863,0.000023179979,0.000026426736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012974163,0.00020037634,0.00016537281,0.00064569386,0.00020887693,0.00042063516,0.00009767237,0.0002827373,0.002077647],"category_scores_gemma":[0.00020800406,0.00017380081,0.0001820419,0.00029188747,0.00017663292,0.00012196065,0.00016860933,0.00023654662,0.0009103791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012662291,0.000009604732,0.0011598243,0.000028121834,0.000012499963,0.0001589074,0.00006233374,0.00003370828,0.996349,0.0001371356,0.00006955569,0.0018527721],"study_design_scores_gemma":[0.000066453365,0.0005563658,0.08309874,0.00003372044,0.00012081259,0.0070620975,0.00019391453,0.0010686364,0.89048684,0.00025786605,0.017031714,0.000022886781],"about_ca_topic_score_codex":0.0006313617,"about_ca_topic_score_gemma":0.00073605037,"teacher_disagreement_score":0.002077647,"about_ca_system_score_codex":0.00018213775,"about_ca_system_score_gemma":0.00011599586,"threshold_uncertainty_score":0.0069503784},"labels":[],"label_agreement":null},{"id":"W1983251100","doi":"10.1111/j.1471-4159.2005.03567.x","title":"Expression of calcineurin and its interacting proteins in epileptic fowl","year":2005,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"Saskatchewan Health Research Foundation; University of Saskatchewan; Bristol-Myers Squibb","keywords":"Calcineurin; Calmodulin; Phosphatase; Immunohistochemistry; Fowl; Biology; Apoptosis; Cell biology; Signal transduction; Calpain; Neuroscience; Internal medicine; Biochemistry; Medicine; Immunology; Phosphorylation; Enzyme; Transplantation","score_opus":0.012819421288848876,"score_gpt":0.2710957611262057,"score_spread":0.2582763398373568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1983251100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99911577,0.00031371132,0.0002429596,0.000018441093,0.0000037414397,0.0000032536711,0.00003803127,0.000004692557,0.0002595362],"genre_scores_gemma":[0.9978941,0.00025229497,0.00060053996,0.000020681544,0.0000035164576,0.000009188747,0.00013984981,0.0000069225953,0.0010729419],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999393,0.0000058991372,0.0000061878227,0.000020471536,0.0000129926475,0.000015129194],"domain_scores_gemma":[0.99984586,0.000028443874,0.000056431298,0.000011579684,0.000024139013,0.000033569228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000089213114,0.00018101292,0.00012959918,0.00042371868,0.00014705128,0.00019737708,0.000103443155,0.00026420862,0.0006363937],"category_scores_gemma":[0.00019349874,0.00016587517,0.00011671415,0.00007316904,0.0003101888,0.00019575904,0.00011714242,0.00018834094,0.00011375472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017283406,0.0000094700235,0.0031278867,0.00003358878,0.0000071869217,0.00034687395,0.00010059798,0.0000150781825,0.9955438,0.00004861725,0.000017586068,0.00057644874],"study_design_scores_gemma":[0.00006244212,0.0010613101,0.36762834,0.000035667697,0.00011443832,0.0076362747,0.0011924338,0.0014591401,0.6179765,0.00022879557,0.0025815663,0.000023088214],"about_ca_topic_score_codex":0.0016442593,"about_ca_topic_score_gemma":0.0028489341,"teacher_disagreement_score":0.0016442593,"about_ca_system_score_codex":0.000335182,"about_ca_system_score_gemma":0.00008573969,"threshold_uncertainty_score":0.0032693744},"labels":[],"label_agreement":null},{"id":"W1984617425","doi":"10.1139/y01-037","title":"Regulation of the ANF and BNP promoters by GATA factors: Lessons learned for cardiac transcription","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Promoter; Transcription factor; Transcription (linguistics); Internal medicine; Cell biology; Biology; Endocrinology; Medicine; Chemistry; Cardiology; Genetics; Gene expression; Gene","score_opus":0.028944378331176312,"score_gpt":0.29001546564764996,"score_spread":0.26107108731647366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1984617425","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13098574,0.7376027,0.090944715,0.022867428,0.0016132346,0.000038474933,0.00042947786,0.00039507778,0.015123138],"genre_scores_gemma":[0.45057765,0.4932168,0.039719164,0.0055043665,0.001509051,0.000095512216,0.00042578377,0.00020160092,0.008750087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996475,0.00005408716,0.000025049738,0.000119209326,0.00008287667,0.00007137844],"domain_scores_gemma":[0.99951386,0.00019227785,0.000030246652,0.00006434227,0.000107659966,0.00009154863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011314383,0.00047274693,0.0008472512,0.00035050508,0.00032840951,0.0010028821,0.00057220395,0.00084307644,0.0008419465],"category_scores_gemma":[0.000792242,0.00028792815,0.00032965108,0.00036055964,0.0020169022,0.0019866782,0.00068438,0.0027480468,0.00051477255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00078994426,0.000102704274,0.003891913,0.002237087,0.00008478191,0.00146394,0.0016323387,0.0037141836,0.45303485,0.10164516,0.00546557,0.42593753],"study_design_scores_gemma":[0.0001922198,0.0007946422,0.01664596,0.0011302807,0.00018625146,0.0039332313,0.0019351848,0.007577469,0.21546105,0.18424602,0.5676554,0.00024235957],"about_ca_topic_score_codex":0.0017900007,"about_ca_topic_score_gemma":0.0020525067,"teacher_disagreement_score":0.0017900007,"about_ca_system_score_codex":0.00093915605,"about_ca_system_score_gemma":0.00078587706,"threshold_uncertainty_score":0.006814122},"labels":[],"label_agreement":null},{"id":"W1985291169","doi":"10.1007/s00395-014-0424-y","title":"Targeting MMP-2 to treat ischemic heart injury","year":2014,"lang":"en","type":"review","venue":"Basic Research in Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Medicine; Myocardial infarction; Ischemia; Cardiology; Heart failure; Intracellular; Clinical trial; Reperfusion injury; Ischemic injury; Extracellular matrix; Bioinformatics; Internal medicine; Neuroscience; Biology; Cell biology","score_opus":0.10938149648762897,"score_gpt":0.4514154317373173,"score_spread":0.34203393524968834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985291169","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034961203,0.99694186,0.00048285423,0.0003906469,0.00033899216,0.000010778302,0.000036353602,0.000019693238,0.0014290605],"genre_scores_gemma":[0.0018703208,0.99569017,0.00048703112,0.00032186293,0.00026576762,0.000014158161,0.000058073427,0.0000035421167,0.0012891042],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998816,0.000013279408,0.000014307916,0.000020850659,0.000054170036,0.000015798953],"domain_scores_gemma":[0.99986124,0.000051482326,0.000025033096,0.000005545439,0.000038245358,0.000018416751],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042772663,0.00094244623,0.0012566497,0.0014039864,0.00018351787,0.0007603684,0.0007238949,0.0008063337,0.0024708055],"category_scores_gemma":[0.0004856574,0.0002699891,0.00041918852,0.001118533,0.00043587963,0.0007746698,0.0004617115,0.0023273902,0.0016875827],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015193688,0.00017228677,0.00012483395,0.0074453703,0.000103978804,0.0002239122,0.000029849238,0.00045248936,0.006666401,0.0025764492,0.035764102,0.9462884],"study_design_scores_gemma":[0.00013046812,0.00022929818,0.0009671032,0.0017862385,0.000241248,0.0015087437,0.000041744563,0.00032220205,0.0033566286,0.0025879627,0.9887939,0.000034415803],"about_ca_topic_score_codex":0.000666392,"about_ca_topic_score_gemma":0.0017086032,"teacher_disagreement_score":0.0024708055,"about_ca_system_score_codex":0.0003778383,"about_ca_system_score_gemma":0.00061680045,"threshold_uncertainty_score":0.0082656145},"labels":[],"label_agreement":null},{"id":"W1985882243","doi":"10.1016/j.jneuroim.2014.08.277","title":"Expression of EMMPRIN on astrocytes: Relevance to normal and diseased brain","year":2014,"lang":"en","type":"article","venue":"Journal of Neuroimmunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"","keywords":"Basigin; Matrix metalloproteinase; Metalloproteinase; Microglia; Cell biology; Context (archaeology); Parenchyma; Chemistry; Neurodegeneration; Neuroinflammation; Proinflammatory cytokine; Astrocyte; Immunology; Neuroscience; Pathology; Biology; Inflammation; Medicine; Central nervous system; Disease; Biochemistry","score_opus":0.008903970072667647,"score_gpt":0.24657327889594538,"score_spread":0.23766930882327775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985882243","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99105835,0.0034142516,0.0026826141,0.00013289652,0.00002447769,0.000012192913,0.00015188032,0.00001943317,0.0025039278],"genre_scores_gemma":[0.99441177,0.0017212421,0.0015107518,0.000034479133,0.000022123453,0.000016355432,0.00017920467,0.000009084229,0.002094975],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998579,0.00003064308,0.000014821813,0.000020274092,0.00003639723,0.00004007034],"domain_scores_gemma":[0.99992216,0.000011985493,0.000015000753,0.000011510957,0.000020041241,0.00001933205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017104656,0.00018117158,0.00017437249,0.00044441444,0.00040583176,0.00043578882,0.00018054715,0.00034670514,0.0005957627],"category_scores_gemma":[0.00020570455,0.0001313776,0.00014724366,0.00023688833,0.00031156253,0.00036501538,0.000328325,0.00036583617,0.00015331761],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00060075993,0.00002408476,0.0021003787,0.0000799816,0.000012352453,0.00072762877,0.00012083772,0.00006382681,0.99129194,0.0011037934,0.00006758952,0.003806644],"study_design_scores_gemma":[0.000026208689,0.00031715014,0.07438877,0.00003424039,0.00007613309,0.005745567,0.0007400917,0.0013607618,0.9090909,0.0017889298,0.006416175,0.000015097999],"about_ca_topic_score_codex":0.00043726666,"about_ca_topic_score_gemma":0.0005233151,"teacher_disagreement_score":0.0005957627,"about_ca_system_score_codex":0.00027735214,"about_ca_system_score_gemma":0.00013166455,"threshold_uncertainty_score":0.002012372},"labels":[],"label_agreement":null},{"id":"W1985955736","doi":"10.1083/jcb.151.3.663","title":"Matching of Calcineurin Activity to Upstream Effectors Is Critical for Skeletal Muscle Fiber Growth","year":2000,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University","funders":"","keywords":"Calcineurin; Biology; Skeletal muscle; Dephosphorylation; Cell biology; Calmodulin; Signal transduction; Upstream and downstream (DNA); Calcium signaling; Phosphatase; Endocrinology; Internal medicine; Enzyme; Phosphorylation; Biochemistry; Upstream (networking); Transplantation","score_opus":0.00919575791738023,"score_gpt":0.2825831903813439,"score_spread":0.27338743246396363,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985955736","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99208015,0.0015863926,0.0045667174,0.00015400756,0.000032965752,0.000021414615,0.00018831936,0.000082699196,0.0012873398],"genre_scores_gemma":[0.996163,0.00055013073,0.0018185904,0.000031998567,0.000009065232,0.00001835003,0.0001771571,0.000020142463,0.001211584],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980074,0.00002210357,0.000018267621,0.000063329026,0.00006194165,0.000033625325],"domain_scores_gemma":[0.9997967,0.00003380689,0.000074892654,0.000021152322,0.000017909113,0.000055585795],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016178982,0.00023844872,0.00020012258,0.00014360795,0.00020986809,0.00042833027,0.00026980537,0.00029393163,0.0009879622],"category_scores_gemma":[0.00020674316,0.00012439997,0.0001378894,0.00013407899,0.0003238345,0.00019670336,0.00030312478,0.00046402146,0.00031855603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000025890553,0.0000072708685,0.000100036494,0.000006291758,6.3162116e-7,0.000012806318,0.0000027205888,0.000013592765,0.99939346,0.00005827847,0.000006263291,0.00037280514],"study_design_scores_gemma":[0.0000138868,0.000114723975,0.0113773085,0.0000054021107,0.000007971492,0.0002537183,0.000020192942,0.0007297312,0.98536855,0.00015394721,0.0019504442,0.000004150839],"about_ca_topic_score_codex":0.00054791704,"about_ca_topic_score_gemma":0.0009940241,"teacher_disagreement_score":0.0009879622,"about_ca_system_score_codex":0.00039928372,"about_ca_system_score_gemma":0.0003715223,"threshold_uncertainty_score":0.0033051372},"labels":[],"label_agreement":null},{"id":"W1986393439","doi":"10.1083/jcb.201305159","title":"Pin1 promotes histone H1 dephosphorylation and stabilizes its binding to chromatin","year":2013,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NOSM University; University of Alberta","funders":"National Institute of General Medical Sciences","keywords":"Histone H1; Biology; Histone H2A; Histone code; Chromatin; Phosphorylation; Histone methyltransferase; Cell biology; Histone-modifying enzymes; Dephosphorylation; Histone; Prolyl isomerase; Chromatin remodeling; PIN1; Molecular biology; Biochemistry; Nucleosome; DNA; Phosphatase","score_opus":0.010595278438841733,"score_gpt":0.25555818461178337,"score_spread":0.24496290617294164,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986393439","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9885942,0.0036092256,0.004559494,0.0001412757,0.000050220337,0.000026500273,0.00029148813,0.00009856953,0.0026291138],"genre_scores_gemma":[0.9959966,0.0007397609,0.0012132076,0.00004056633,0.000009951015,0.000013617649,0.00027125055,0.000012676966,0.0017022063],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998902,0.000013388705,0.0000053962267,0.0000325955,0.000025013776,0.000033436143],"domain_scores_gemma":[0.99993646,0.000011742492,0.000017010503,0.000005740522,0.0000045495185,0.000024501547],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010651618,0.00035265554,0.0002279894,0.00016307378,0.00017908635,0.00034793175,0.00022470906,0.00022046843,0.001678547],"category_scores_gemma":[0.00011313055,0.00019487723,0.00020120319,0.000085011605,0.00020738006,0.00021013581,0.00034912094,0.00054696004,0.00041147388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009436852,0.00001189663,0.000101962185,0.0000385823,0.0000031334346,0.000040665313,0.0000053984004,0.000049495415,0.99868006,0.00011409024,0.000028628105,0.0008316857],"study_design_scores_gemma":[0.0000070913934,0.0000724341,0.0027696625,0.0000032663818,0.000005346385,0.00015724025,0.000012025134,0.0006680936,0.9946004,0.000049614355,0.001651362,0.0000035072414],"about_ca_topic_score_codex":0.00029924093,"about_ca_topic_score_gemma":0.0005131588,"teacher_disagreement_score":0.001678547,"about_ca_system_score_codex":0.0003257618,"about_ca_system_score_gemma":0.000113119335,"threshold_uncertainty_score":0.0056153536},"labels":[],"label_agreement":null},{"id":"W1986804594","doi":"10.1016/j.bpj.2014.11.2295","title":"Identification of Major FKBP12 Binding Determinants in RyR1","year":2015,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"FKBP; RYR1; Ryanodine receptor; Binding site; Chemistry; Biology; Cell biology; Biochemistry; Receptor","score_opus":0.023695643658543833,"score_gpt":0.2946620789638632,"score_spread":0.2709664353053194,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1986804594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99021417,0.00068447733,0.0068387412,0.0002173707,0.000038712045,0.000031597872,0.00049930625,0.00009104079,0.0013846807],"genre_scores_gemma":[0.99170285,0.00019450957,0.004538151,0.0001279027,0.000018169982,0.00003252286,0.00082919584,0.000042262676,0.0025143684],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988055,0.00001833586,0.000010542622,0.00003305933,0.00002485346,0.000032660253],"domain_scores_gemma":[0.9996995,0.00007745083,0.00006520061,0.000030321995,0.000039548508,0.00008807158],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016382578,0.000385252,0.00041707692,0.00028306662,0.00039411284,0.00035036978,0.00041572988,0.0003952414,0.004294589],"category_scores_gemma":[0.00038574426,0.00021481913,0.0004180231,0.0001643319,0.00024650132,0.00019218076,0.00032748282,0.0007970401,0.001303253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031561562,0.000029239727,0.00049064984,0.00003071102,0.000007432776,0.0001390976,0.00003303659,0.000115523,0.99681145,0.00037028437,0.000115876755,0.001541106],"study_design_scores_gemma":[0.00003516796,0.00016593983,0.031529073,0.000017722476,0.00003685989,0.0011653261,0.00009350072,0.0038031528,0.9591524,0.00032934643,0.0036447835,0.000026775379],"about_ca_topic_score_codex":0.0018896268,"about_ca_topic_score_gemma":0.002481173,"teacher_disagreement_score":0.004294589,"about_ca_system_score_codex":0.00056011893,"about_ca_system_score_gemma":0.00023886672,"threshold_uncertainty_score":0.014366865},"labels":[],"label_agreement":null},{"id":"W1987286072","doi":"10.1016/j.molimm.2005.10.019","title":"The usage of alternative splice sites in mus musculus synaptotagmin-like 2 gene is modulated by cyclosporin A and FK506 in T-lymphocytes","year":2006,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Rural Development Administration; Fondation pour la Recherche Médicale; Centre National de la Recherche Scientifique; Association pour la Recherche sur le Cancer","keywords":"Exon; Intron; Gene isoform; Alternative splicing; Gene; splice; Biology; Transcription (linguistics); Molecular biology; Transcription preinitiation complex; Coding region; Synaptotagmin 1; Genetics; Gene expression; Promoter","score_opus":0.0033839014236594295,"score_gpt":0.20929276943313482,"score_spread":0.2059088680094754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1987286072","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980192,0.0005332973,0.0009222169,0.00004308988,0.000018579569,0.000004806526,0.00012307292,0.000015736563,0.000319999],"genre_scores_gemma":[0.9978016,0.00018495874,0.00059583405,0.000039397983,0.000012444875,0.0000121017265,0.0004145749,0.000018337321,0.0009206605],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982315,0.000037282633,0.000017358021,0.000047906287,0.000034531018,0.00003972389],"domain_scores_gemma":[0.9997737,0.00004500534,0.000067582536,0.00002562589,0.000020504423,0.00006756733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015275406,0.00026136095,0.00020702464,0.00036242572,0.00024058782,0.0003114304,0.00023550467,0.0002780787,0.0010310678],"category_scores_gemma":[0.00014757959,0.00021075581,0.00034165056,0.00016408577,0.00026064552,0.00016778211,0.00027193077,0.0005195695,0.00041263268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015491563,0.000011000852,0.00036980325,0.000010147196,0.0000049676737,0.00005318318,0.000012377499,0.000023620652,0.9987533,0.00013958897,0.000017225755,0.0004497798],"study_design_scores_gemma":[0.00008454872,0.00040095355,0.058020685,0.000022415705,0.00009503512,0.0013365035,0.00011521194,0.002125791,0.9341857,0.00031216734,0.0032782366,0.000022794424],"about_ca_topic_score_codex":0.00039788484,"about_ca_topic_score_gemma":0.0012928396,"teacher_disagreement_score":0.0010310678,"about_ca_system_score_codex":0.00029934538,"about_ca_system_score_gemma":0.00015400113,"threshold_uncertainty_score":0.0034492612},"labels":[],"label_agreement":null},{"id":"W1988029417","doi":"10.1002/jcb.20437","title":"Increased expression of calcineurin in human colorectal adenocarcinomas","year":2005,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Western blot; Calcineurin; Immunohistochemistry; Colorectal cancer; Phosphatase; Biology; Signal transduction; Calmodulin; Blot; Cytoplasm; Cancer research; Cancer; Molecular biology; Pathology; Cell biology; Medicine; Enzyme; Phosphorylation; Immunology; Internal medicine; Biochemistry; Gene; Genetics","score_opus":0.007659045999593702,"score_gpt":0.2426109403558185,"score_spread":0.23495189435622482,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988029417","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970758,0.0016351875,0.0004148555,0.00001937511,0.000007741846,0.000009407404,0.00011473687,0.000018960085,0.000703849],"genre_scores_gemma":[0.99803907,0.00073886727,0.00047849223,0.000012448846,0.0000058919145,0.0000062251625,0.00025442976,0.0000033535791,0.00046126934],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998833,0.000013639119,0.000011571474,0.00002299654,0.00004416707,0.000024222314],"domain_scores_gemma":[0.9998536,0.000025586201,0.000036325706,0.000019800598,0.00002959061,0.000035045312],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010906911,0.00016900273,0.0001395312,0.000590823,0.00017257732,0.00026727276,0.000069429225,0.00017047489,0.00059482653],"category_scores_gemma":[0.00022664778,0.00011548046,0.00011858787,0.00035149758,0.00017338735,0.00009930904,0.00015183572,0.00012350935,0.00014638815],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027808003,0.000017698454,0.020597156,0.000073190684,0.000017673085,0.0013629998,0.000087824556,0.000029292069,0.9751025,0.00004942148,0.000042171647,0.0023421021],"study_design_scores_gemma":[0.00004408287,0.00074517453,0.6018157,0.000016859118,0.00011393713,0.02627794,0.00040779932,0.00080471754,0.36348337,0.00015762313,0.0061172494,0.000015688072],"about_ca_topic_score_codex":0.00092299056,"about_ca_topic_score_gemma":0.001036927,"teacher_disagreement_score":0.00092299056,"about_ca_system_score_codex":0.0001493218,"about_ca_system_score_gemma":0.00011792853,"threshold_uncertainty_score":0.001989901},"labels":[],"label_agreement":null},{"id":"W1988252474","doi":"10.1007/s11060-012-0927-z","title":"Mechanism for the induction of cell death in ONS-76 medulloblastoma cells by Zhangfei/CREB-ZF","year":2012,"lang":"en","type":"article","venue":"Journal of Neuro-Oncology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Biology; Cell biology; MAPK/ERK pathway; Transcription factor; Signal transduction; CREB; Autocrine signalling; Protein kinase A; AP-1 transcription factor; Kinase; Autophagy; Molecular biology; Apoptosis; Cell culture; Gene; Genetics","score_opus":0.022711378089325,"score_gpt":0.2853210070440694,"score_spread":0.2626096289547444,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988252474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9517288,0.004651995,0.027962193,0.0015625759,0.00035216563,0.00025744506,0.0026013951,0.0012596273,0.009623763],"genre_scores_gemma":[0.98704123,0.00091805443,0.0034934457,0.00012653857,0.000018104625,0.0001715746,0.00072778214,0.000034149372,0.007469124],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983656,0.000011196883,0.000011751726,0.00003661708,0.00004478629,0.000059009144],"domain_scores_gemma":[0.999925,0.000007141252,0.000020751839,0.000016740152,0.000010860931,0.000019541938],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021744342,0.00055097626,0.00038361823,0.00047372558,0.00054932735,0.00034185286,0.0006826828,0.0004954696,0.0032501484],"category_scores_gemma":[0.00011135229,0.00022347858,0.0007164921,0.00019919034,0.00039358065,0.00049373956,0.00031570886,0.0013561461,0.0006761692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018443837,0.000057008,0.0003134848,0.0001004837,0.000013730859,0.00022898542,0.0000326039,0.00013465532,0.9941075,0.0022302556,0.00033200203,0.002264838],"study_design_scores_gemma":[0.000056502915,0.00010583594,0.0033769838,0.000008303201,0.000016308759,0.0003711439,0.000034928824,0.0008678538,0.9921095,0.00027443847,0.0027696379,0.00000850343],"about_ca_topic_score_codex":0.0016182323,"about_ca_topic_score_gemma":0.0014016478,"teacher_disagreement_score":0.0032501484,"about_ca_system_score_codex":0.00080701895,"about_ca_system_score_gemma":0.00042016225,"threshold_uncertainty_score":0.010872841},"labels":[],"label_agreement":null},{"id":"W1989139935","doi":"10.1139/y10-067","title":"Reversal of isoprenaline-induced cardiac remodeling by rutaecarpine via stimulation of calcitonin gene-related peptide production","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Rutaecarpine; Isoprenaline; Calcitonin gene-related peptide; Internal medicine; Endocrinology; Calcitonin; Capsaicin; Ventricle; Cardiac function curve; Stimulation; Chemistry; Ventricular remodeling; Medicine; Pharmacology; Heart failure; Receptor; Neuropeptide","score_opus":0.008315427350228806,"score_gpt":0.2562526188890241,"score_spread":0.24793719153879532,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989139935","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910047,0.0032019836,0.0027742712,0.00020390737,0.000064186905,0.000074538606,0.0002224412,0.00027193938,0.002182132],"genre_scores_gemma":[0.9923293,0.0027892147,0.002688584,0.00010636333,0.000034000044,0.0000639403,0.00037652857,0.00002500931,0.0015870348],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992645,0.000016629048,0.000006563216,0.000011145238,0.000016745349,0.00002252886],"domain_scores_gemma":[0.99990344,0.00001622371,0.000030418701,0.000013118052,0.000009789034,0.000027027874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010562448,0.0004466895,0.0003751962,0.0003749788,0.00012716508,0.00017514585,0.0002638147,0.00026941058,0.001035885],"category_scores_gemma":[0.0001880144,0.00012634452,0.00028925904,0.00016685328,0.0003241879,0.00026447754,0.00017545608,0.0008445643,0.00019750734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004916883,0.00014658668,0.0000702813,0.00008765896,0.000010618016,0.00010050227,0.000020340902,0.00007630607,0.9953576,0.00009500683,0.00005303553,0.0034904263],"study_design_scores_gemma":[0.00024661576,0.002299899,0.0077965544,0.000020627922,0.000054369055,0.00039038502,0.000048080514,0.0010166058,0.98582226,0.000099873425,0.002188159,0.000016461516],"about_ca_topic_score_codex":0.0005545531,"about_ca_topic_score_gemma":0.00084926543,"teacher_disagreement_score":0.001035885,"about_ca_system_score_codex":0.00014725488,"about_ca_system_score_gemma":0.00025934115,"threshold_uncertainty_score":0.003465414},"labels":[],"label_agreement":null},{"id":"W1989355680","doi":"10.1016/j.micres.2006.08.002","title":"Inhibitory activity against papain, a CA1 cysteine peptidase, in Saccharomycetaceae","year":2006,"lang":"en","type":"article","venue":"Microbiological Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Centre National de la Recherche Scientifique","keywords":"Papain; Yeast; Biology; Cysteine; Biochemistry; Enzyme; Intracellular; Cysteine Proteinase Inhibitors; Inhibitory postsynaptic potential; Saccharomyces cerevisiae; Biological activity; Proteases; In vitro","score_opus":0.037479976025045984,"score_gpt":0.3265590289971767,"score_spread":0.2890790529721307,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1989355680","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946003,0.0034599754,0.00086553924,0.000045934547,0.000014082731,0.0000069090497,0.00013096833,0.00003672087,0.00083960575],"genre_scores_gemma":[0.9971227,0.0010790492,0.00052927015,0.000019455048,0.000008366043,0.0000060428,0.00044639944,0.000005948758,0.000782862],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989474,0.000018934415,0.000010154735,0.000014321823,0.000031478685,0.000030358504],"domain_scores_gemma":[0.9998543,0.00003031637,0.000027447966,0.000016285941,0.000025234505,0.00004637429],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014288335,0.000379522,0.00025592296,0.00029697633,0.00018203774,0.00027830253,0.00017523771,0.00018492858,0.00037829296],"category_scores_gemma":[0.00025358348,0.000106219406,0.00017153769,0.0002643974,0.0002114083,0.00011498862,0.00012112329,0.00034344615,0.00014428078],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015109111,0.000013602388,0.00034830667,0.00002464322,0.0000032602888,0.000041899544,0.000009287044,0.000046432517,0.9980002,0.000029096851,0.0000168098,0.001315401],"study_design_scores_gemma":[0.000009223295,0.00029234533,0.008012716,0.0000035254466,0.000016612366,0.00029642624,0.000017918162,0.00042004808,0.9899462,0.000026799076,0.00095520803,0.0000030275999],"about_ca_topic_score_codex":0.0024354754,"about_ca_topic_score_gemma":0.0017531519,"teacher_disagreement_score":0.0024354754,"about_ca_system_score_codex":0.00041318926,"about_ca_system_score_gemma":0.0002384669,"threshold_uncertainty_score":0.0048425198},"labels":[],"label_agreement":null},{"id":"W1990422646","doi":"10.1002/prp2.76","title":"Analysis of FK506, timcodar (VX‐853) and FKBP51 and FKBP52 chaperones in control of glucocorticoid receptor activity and phosphorylation","year":2014,"lang":"en","type":"article","venue":"Pharmacology Research & Perspectives","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; College of Graduate Studies, University of Toledo; National Institutes of Health; School of Medicine, New York University; York University; Stranahan Foundation; National Institute on Minority Health and Health Disparities; University of Toledo Foundation","keywords":"FKBP; Phosphorylation; Glucocorticoid receptor; Receptor; Endocrinology; Internal medicine; Glucocorticoid; Chemistry; Molecular biology; Biology; Cell biology; Medicine","score_opus":0.020045100937088774,"score_gpt":0.3588516178492234,"score_spread":0.33880651691213465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990422646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9974916,0.0011540432,0.00065645477,0.0000468381,0.00001187776,0.0000076033602,0.00019216572,0.000014497153,0.00042482786],"genre_scores_gemma":[0.9972806,0.0006183713,0.0006049498,0.000027320062,0.000005653309,0.000015343738,0.0004005399,0.000006187187,0.0010409914],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992573,0.000010569666,0.000009388088,0.000017033954,0.000013664487,0.000023481045],"domain_scores_gemma":[0.9999398,0.00000728034,0.000021991978,0.0000065483614,0.0000044215312,0.00002002872],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007277816,0.00024153912,0.00020053746,0.00011713281,0.00011392526,0.00020837484,0.00017873239,0.00019440713,0.0007819016],"category_scores_gemma":[0.000050591665,0.000093234616,0.0002563352,0.000113360984,0.00014800546,0.00013947891,0.000095209776,0.00024462852,0.00019342588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012539528,0.0000067212422,0.0001432872,0.00001090596,0.0000025938582,0.000020679205,0.0000033116746,0.00001854167,0.999383,0.00003213554,0.000005624045,0.00024769024],"study_design_scores_gemma":[0.000024190726,0.00026706982,0.018378103,0.0000042599436,0.000029678724,0.00030578297,0.000030520736,0.0007704601,0.97886825,0.000030227022,0.0012867475,0.0000048930333],"about_ca_topic_score_codex":0.00049648556,"about_ca_topic_score_gemma":0.00065440685,"teacher_disagreement_score":0.0007819016,"about_ca_system_score_codex":0.0002324582,"about_ca_system_score_gemma":0.00010051501,"threshold_uncertainty_score":0.0026156902},"labels":[],"label_agreement":null},{"id":"W1990518792","doi":"10.1073/pnas.1013555107","title":"Constitutively active calcineurin induces cardiac endoplasmic reticulum stress and protects against apoptosis that is mediated by α-crystallin-B","year":2010,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Toronto General Hospital; Heart and Stroke Foundation; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Calcineurin; Endoplasmic reticulum; Apoptosis; Cell biology; Biology; Proteome; Unfolded protein response; Transcriptome; ATF6; Molecular biology; Biochemistry; Transplantation; Gene expression; Internal medicine; Medicine; Gene","score_opus":0.02032960569051562,"score_gpt":0.2682139086709771,"score_spread":0.2478843029804615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990518792","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9969963,0.00085816166,0.001320714,0.000085448875,0.000022024085,0.000021993863,0.00023144316,0.00006361271,0.00040034534],"genre_scores_gemma":[0.99580944,0.0007391931,0.0016220468,0.00006458594,0.00001139853,0.00004213338,0.00059271266,0.00001927679,0.0010992334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998265,0.000023122517,0.00002387601,0.000039219496,0.000050619947,0.000036644866],"domain_scores_gemma":[0.9997781,0.000033480123,0.00007504791,0.00003229747,0.000019275662,0.00006173661],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002303147,0.0003325364,0.00030430473,0.00030442807,0.00018549935,0.00027118772,0.00022345409,0.0002584927,0.00053541956],"category_scores_gemma":[0.00015485148,0.0001549596,0.00027855788,0.0002049942,0.00027109592,0.00017985626,0.00019256854,0.00058872404,0.0001451623],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006130842,0.000013546894,0.00009774622,0.000012709864,0.0000034034304,0.00001894691,0.0000057187244,0.00001538162,0.99951494,0.00001682382,0.000008382948,0.00023092101],"study_design_scores_gemma":[0.000035557736,0.00044477746,0.012141347,0.0000080034015,0.000021061876,0.0003175695,0.000032872234,0.0013294327,0.98457307,0.00006201823,0.0010286799,0.000005672064],"about_ca_topic_score_codex":0.00057140854,"about_ca_topic_score_gemma":0.00084030104,"teacher_disagreement_score":0.00057140854,"about_ca_system_score_codex":0.00023995347,"about_ca_system_score_gemma":0.00026130714,"threshold_uncertainty_score":0.0017911792},"labels":[],"label_agreement":null},{"id":"W1990538706","doi":"10.1016/s0009-9120(99)00080-6","title":"Minor immunophilin binding of tacrolimus and sirolimus metabolites","year":2000,"lang":"en","type":"article","venue":"Clinical Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Tacrolimus; Sirolimus; FKBP; Chemistry; Minor (academic); Medicine; Internal medicine; Biochemistry; Transplantation","score_opus":0.016739194379428526,"score_gpt":0.3086126759633901,"score_spread":0.2918734815839616,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990538706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97836566,0.0047449744,0.006417018,0.0003766074,0.00009230631,0.000042738648,0.00029025605,0.000102856575,0.009567604],"genre_scores_gemma":[0.99211895,0.000928738,0.001282749,0.00009311351,0.00003555732,0.000020447402,0.00039719604,0.000013993111,0.005109268],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996872,0.00010461823,0.000014666873,0.000033979177,0.000061622886,0.0000979061],"domain_scores_gemma":[0.99980646,0.000057758985,0.00003208931,0.000019445226,0.000026301987,0.00005799395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026219306,0.000330856,0.00025143166,0.0003690214,0.00034306673,0.00039311888,0.0002823303,0.00033360303,0.004031212],"category_scores_gemma":[0.00045284888,0.00022674439,0.00025586635,0.00018786853,0.0001484105,0.00016727224,0.00028168285,0.00041404905,0.0007485175],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00084513234,0.000049887254,0.0008896928,0.00004617752,0.00002268986,0.00020599493,0.000031133943,0.00018703342,0.991372,0.0008337061,0.0002046427,0.005312003],"study_design_scores_gemma":[0.000028693417,0.00025129144,0.01643842,0.000009189493,0.000022208404,0.0005615518,0.000039839295,0.0019568305,0.9768355,0.00024676425,0.003601785,0.000007975614],"about_ca_topic_score_codex":0.0012838911,"about_ca_topic_score_gemma":0.001792027,"teacher_disagreement_score":0.004031212,"about_ca_system_score_codex":0.00049041165,"about_ca_system_score_gemma":0.00035797956,"threshold_uncertainty_score":0.01348573},"labels":[],"label_agreement":null},{"id":"W1990820409","doi":"10.1016/j.bbadis.2010.07.018","title":"The many faces of EMMPRIN—Roles in neuroinflammation","year":2010,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; Ontario Brain Institute","funders":"","keywords":"Neuroinflammation; Blood–brain barrier; Immune system; Matrix metalloproteinase; Inflammation; Proteases; Proinflammatory cytokine; Immunology; Extracellular matrix; Neuroscience; Context (archaeology); Microglia; Biology; Cell biology; Central nervous system","score_opus":0.01463763060343117,"score_gpt":0.29397391782933785,"score_spread":0.2793362872259067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1990820409","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002170331,0.99739647,0.0002493233,0.0005782388,0.00032916322,0.000003009102,0.000017084214,0.000008811965,0.0012010089],"genre_scores_gemma":[0.0011715508,0.9965898,0.00033260894,0.00027900084,0.00039434456,0.0000049586906,0.000033846125,0.0000016551752,0.0011922299],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998808,0.000014227609,0.000017470029,0.00001921016,0.000053322892,0.000014977891],"domain_scores_gemma":[0.99985325,0.000045683886,0.000022032373,0.000006551604,0.000046161695,0.000026281828],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005399825,0.00084101,0.0009539257,0.0009786148,0.0002575898,0.00111602,0.0008458239,0.0010354281,0.0018744183],"category_scores_gemma":[0.00045279667,0.00028184484,0.00019981294,0.0014334128,0.000697789,0.0019702043,0.000867401,0.0019510791,0.0016410688],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012752405,0.00003541573,0.00026218093,0.0033628712,0.000063825326,0.00025885153,0.000038331862,0.0003266802,0.004882994,0.006379527,0.03997353,0.9442882],"study_design_scores_gemma":[0.000015021054,0.000028849377,0.0010059796,0.0006168528,0.0000442776,0.0009773191,0.00005503032,0.000110779816,0.0010205234,0.0032426782,0.9928678,0.000014969644],"about_ca_topic_score_codex":0.000750007,"about_ca_topic_score_gemma":0.0012775856,"teacher_disagreement_score":0.0018744183,"about_ca_system_score_codex":0.00063449936,"about_ca_system_score_gemma":0.00071880856,"threshold_uncertainty_score":0.006270528},"labels":[],"label_agreement":null},{"id":"W1991017196","doi":"10.1016/j.ydbio.2013.09.015","title":"Pocket proteins pRb and p107 are required for cortical lamination independent of apoptosis","year":2013,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Hospital for Sick Children; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Biology; Ectopic expression; Cell biology; Apoptosis; Cell cycle; Programmed cell death; Cell; Cell migration; Retinoblastoma protein; Population; Neuroscience; Genetics; Cell culture","score_opus":0.016573020711762424,"score_gpt":0.253665396909611,"score_spread":0.23709237619784856,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991017196","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98519576,0.0031784067,0.00665408,0.00042106086,0.00008012333,0.00002217778,0.0004488641,0.0005568112,0.0034428115],"genre_scores_gemma":[0.994131,0.00040412057,0.0022775063,0.0000586314,0.000009178967,0.000019757297,0.00040712353,0.00008948053,0.0026032284],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997336,0.000027832959,0.000023980057,0.00004248101,0.00008696021,0.00008510097],"domain_scores_gemma":[0.99940026,0.00009153326,0.00017962662,0.00011795423,0.000037828722,0.00017270389],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019704575,0.00040572014,0.00041487496,0.00038332157,0.00035931353,0.0008857808,0.0004784418,0.00059112353,0.0019944685],"category_scores_gemma":[0.000435837,0.0004957242,0.0002851061,0.00016904657,0.0005821602,0.0006324385,0.0007201545,0.0014187079,0.0012027681],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022918268,0.000009546765,0.0002688978,0.000026151638,0.0000047462354,0.00020961385,0.000009513673,0.000035089837,0.99761766,0.0003414991,0.00010047248,0.0011476261],"study_design_scores_gemma":[0.0000639912,0.00009193298,0.017802836,0.000008498881,0.00001773051,0.0026210046,0.00009527409,0.0013769107,0.9742182,0.00069201586,0.0030005737,0.000011037383],"about_ca_topic_score_codex":0.0003600734,"about_ca_topic_score_gemma":0.00071558525,"teacher_disagreement_score":0.0019944685,"about_ca_system_score_codex":0.00050456193,"about_ca_system_score_gemma":0.000303971,"threshold_uncertainty_score":0.006672144},"labels":[],"label_agreement":null},{"id":"W1991180491","doi":"10.1021/bi802242r","title":"Characterization of Lipid Binding Specificities of Dysferlin C2 Domains Reveals Novel Interactions with Phosphoinositides","year":2009,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":103,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Dysferlin; Phosphatidylinositol; Phosphatidylserine; Chemistry; Transmembrane domain; Transmembrane protein; Biochemistry; Cell biology; Plasma protein binding; Membrane; Phospholipid; Biology; Signal transduction; Receptor","score_opus":0.011370490420725451,"score_gpt":0.23710151511231292,"score_spread":0.22573102469158746,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991180491","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9986241,0.00033603134,0.00048734993,0.000022898643,0.0000024152537,0.0000066009507,0.00014969404,0.000004446172,0.0003665027],"genre_scores_gemma":[0.99767774,0.00014860505,0.00091408135,0.00005438663,0.0000025775742,0.000012323921,0.00047711443,0.0000042965985,0.0007088938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991465,0.000019474537,0.0000057644525,0.00001754845,0.00002020849,0.000022373068],"domain_scores_gemma":[0.9998996,0.00003163515,0.000015094725,0.000008462772,0.000018637738,0.000026564881],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012088848,0.00033321997,0.00016974483,0.00019431095,0.00012345107,0.00019352218,0.00018229238,0.00021643404,0.0007717207],"category_scores_gemma":[0.00017621508,0.00009656779,0.00012722694,0.00013844155,0.00011576293,0.00013380121,0.00016109817,0.00021770711,0.0002289245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011368017,0.000011115777,0.0005842297,0.000013326611,0.0000046741916,0.000079847276,0.000017780434,0.00006005546,0.9986119,0.000044653523,0.000025352658,0.00043341532],"study_design_scores_gemma":[0.000017289174,0.00012306127,0.025018347,0.0000067270685,0.00001739305,0.00087617827,0.000068151305,0.0025894458,0.9687734,0.000075429714,0.0024243896,0.000010024784],"about_ca_topic_score_codex":0.0012000874,"about_ca_topic_score_gemma":0.0017438335,"teacher_disagreement_score":0.0012000874,"about_ca_system_score_codex":0.00031400716,"about_ca_system_score_gemma":0.00008713862,"threshold_uncertainty_score":0.0025817156},"labels":[],"label_agreement":null},{"id":"W1992697077","doi":"10.1016/s0893-133x(01)00269-x","title":"Tetraspan Protein CD151 A Common Target of Mood Stabilizing Drugs?","year":2001,"lang":"en","type":"article","venue":"Neuropsychopharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Alliance for Research on Schizophrenia and Depression","keywords":"Imipramine; Lithium (medication); Mood stabilizer; Tricyclic; Pharmacology; Antidepressant; Antipsychotic; Carbamazepine; Mood disorders; Bipolar disorder; Neuroprotection; Medicine; Neuroscience; Biology; Internal medicine; Psychiatry; Hippocampus; Schizophrenia (object-oriented programming)","score_opus":0.011594193167033346,"score_gpt":0.28979289932978314,"score_spread":0.2781987061627498,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1992697077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9190077,0.04974009,0.005864492,0.00550129,0.00065770024,0.000112441514,0.0005702157,0.00021062428,0.018335477],"genre_scores_gemma":[0.9820972,0.009017203,0.0014135733,0.00091802777,0.00012785173,0.000044416025,0.00029757735,0.000010676429,0.0060734437],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998841,0.000020428204,0.0000089163395,0.000029328796,0.000019617453,0.00003743776],"domain_scores_gemma":[0.9999434,0.0000036111505,0.000019882651,0.0000074135723,0.0000103456905,0.000015359756],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017831789,0.00026588733,0.00058710465,0.00020917886,0.000273207,0.0005766425,0.00029727348,0.00070417713,0.0033786544],"category_scores_gemma":[0.0001596724,0.00011178743,0.00032793614,0.0002037762,0.0002520913,0.00046859353,0.0003061231,0.00045669146,0.000956781],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004039845,0.00022441517,0.0059848353,0.0003772134,0.0001654093,0.0026768546,0.00013750918,0.00048484126,0.8488615,0.009482331,0.0037009371,0.12386414],"study_design_scores_gemma":[0.00090191985,0.004575498,0.09750564,0.00023003879,0.00062114326,0.020681202,0.0011005612,0.004797601,0.7127494,0.013483073,0.14325625,0.00009775259],"about_ca_topic_score_codex":0.00035674882,"about_ca_topic_score_gemma":0.00047521477,"teacher_disagreement_score":0.0033786544,"about_ca_system_score_codex":0.0004630194,"about_ca_system_score_gemma":0.00030747385,"threshold_uncertainty_score":0.011302769},"labels":[],"label_agreement":null},{"id":"W1993562598","doi":"10.1007/s004380051197","title":"The yeast peptidyl proline isomerases FPR3 and FPR4, in high copy numbers, suppress defects resulting from the absence of the E3 ubiquitin ligase TOM1","year":2000,"lang":"en","type":"article","venue":"Molecular and General Genetics MGG","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Biology; Ubiquitin ligase; Gene; Ubiquitin; Trans-acting; Plasmid; Homology (biology); Genetics; Isomerase; Molecular biology; Biochemistry; Mutant","score_opus":0.004824871189780508,"score_gpt":0.2200014749744264,"score_spread":0.2151766037846459,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993562598","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9802229,0.0033818716,0.0107009085,0.00022990388,0.00006610858,0.000040532792,0.0015119833,0.00133393,0.0025118364],"genre_scores_gemma":[0.98425496,0.0009982444,0.008030542,0.0000651028,0.000016800437,0.000025580792,0.0018379621,0.0003285361,0.004442364],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996964,0.00005220944,0.000028922905,0.00005888209,0.00010943804,0.000054210075],"domain_scores_gemma":[0.9994548,0.00012014955,0.0001712005,0.000090344016,0.000036673537,0.00012684731],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023545865,0.0014174195,0.0005442037,0.0008962849,0.00022920515,0.0006332727,0.0006538685,0.0004923093,0.0012059693],"category_scores_gemma":[0.00035762857,0.00037210115,0.00042173508,0.00048191563,0.00067558204,0.00028023074,0.0006327761,0.00081598776,0.0012624165],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000120494944,0.000010834765,0.00012823893,0.000020614765,0.000008459128,0.000082898645,0.000006828971,0.00009438618,0.99789006,0.00014190329,0.000059939463,0.0014354246],"study_design_scores_gemma":[0.000019687335,0.000054759636,0.0012055396,0.0000037629984,0.000016256408,0.0005246868,0.000019522115,0.00079397723,0.99559337,0.00011288759,0.0016491882,0.0000062783997],"about_ca_topic_score_codex":0.0011876068,"about_ca_topic_score_gemma":0.0015777797,"teacher_disagreement_score":0.0014174195,"about_ca_system_score_codex":0.00078317075,"about_ca_system_score_gemma":0.0002773574,"threshold_uncertainty_score":0.005682349},"labels":[],"label_agreement":null},{"id":"W1993933934","doi":"10.1074/jbc.m201195200","title":"Characterization of New Cell Permeable C3-like Proteins That Inactivate Rho and Stimulate Neurite Outgrowth on Inhibitory Substrates","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":128,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Neurite; Cell biology; Inhibitory postsynaptic potential; Growth cone; Immunocytochemistry; Fusion protein; Cell culture; Chemistry; Recombinant DNA; Biology; Molecular biology; Biochemistry; In vitro; Axon; Neuroscience","score_opus":0.031157551690687704,"score_gpt":0.22414122028058603,"score_spread":0.19298366858989832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1993933934","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887601,0.0010117396,0.008895662,0.00008939229,0.00001432708,0.0000818343,0.0005535151,0.000052427175,0.000540923],"genre_scores_gemma":[0.976991,0.00091242074,0.016908504,0.0001602001,0.000010120431,0.00011702866,0.0027440211,0.000060810788,0.0020958295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986446,0.000018293089,0.00001308593,0.00002547074,0.000048042963,0.00003058862],"domain_scores_gemma":[0.99971396,0.0000600772,0.000074586744,0.000029648332,0.000058392307,0.00006331302],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026769456,0.0005109532,0.00029755934,0.00020063308,0.00018272134,0.0004002248,0.00030477977,0.00050053693,0.0005174071],"category_scores_gemma":[0.000304388,0.00011269406,0.00052614574,0.00028342658,0.00031177234,0.0002129383,0.00014879747,0.0006878918,0.0003343739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000042473064,0.000015761474,0.00005255584,0.000019692565,0.0000034929014,0.000028909117,0.000009839585,0.00009289781,0.9993399,0.00004649728,0.000016866623,0.00033111972],"study_design_scores_gemma":[0.000015922096,0.00018314613,0.0015370025,0.000004671508,0.000015483054,0.00027973336,0.000017518383,0.0010977581,0.9945422,0.000018685054,0.0022809266,0.000006996846],"about_ca_topic_score_codex":0.0018408842,"about_ca_topic_score_gemma":0.001322773,"teacher_disagreement_score":0.0018408842,"about_ca_system_score_codex":0.00090959016,"about_ca_system_score_gemma":0.0004037734,"threshold_uncertainty_score":0.006599605},"labels":[],"label_agreement":null},{"id":"W1994236253","doi":"10.1158/0008-5472.can-03-3448","title":"Recent Advances in Stress Signaling in Cancer","year":2004,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Signal transduction; Cancer; Apoptosis; Cancer cell; Biology; Mechanism (biology); Neuroscience; Cancer research; Cell biology; Genetics","score_opus":0.06743361268537813,"score_gpt":0.4287545266342851,"score_spread":0.361320913948907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994236253","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013527038,0.9718407,0.0005697597,0.017987337,0.005126033,0.000007970311,0.00002439308,0.000029480943,0.003061706],"genre_scores_gemma":[0.010020984,0.9680843,0.0009070372,0.0052381465,0.013152027,0.0000127131125,0.00007078056,0.000007774046,0.0025062212],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99962723,0.000099358134,0.000056102446,0.00005366726,0.000095545125,0.00006800293],"domain_scores_gemma":[0.9987697,0.0004882156,0.00009722049,0.00004045574,0.0002820908,0.0003223117],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0026564961,0.0006087196,0.0008259628,0.00146547,0.00064445473,0.002098789,0.00057769846,0.0019527847,0.0023976625],"category_scores_gemma":[0.0009983749,0.00035291084,0.00038945125,0.0015478728,0.001307515,0.0029288102,0.0010235914,0.0031502363,0.0009450359],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008060488,0.00020506226,0.0010029956,0.005840867,0.0001295998,0.00069527834,0.00046135572,0.0011595208,0.012294288,0.025192445,0.13630554,0.81590706],"study_design_scores_gemma":[0.000044869696,0.00021126521,0.0015427718,0.00055070926,0.000074964155,0.00075664633,0.0002460269,0.00032556235,0.0020436037,0.009250908,0.9849251,0.000027573458],"about_ca_topic_score_codex":0.00063154555,"about_ca_topic_score_gemma":0.0017220279,"teacher_disagreement_score":0.0026564961,"about_ca_system_score_codex":0.0013047621,"about_ca_system_score_gemma":0.0010532552,"threshold_uncertainty_score":0.014049053},"labels":[],"label_agreement":null},{"id":"W1994729367","doi":"10.1074/jbc.m010717200","title":"A Family of 16-kDa Pancreatic Secretory Stress Proteins Form Highly Organized Fibrillar Structures upon Tryptic Activation","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pancreas Centre (Canada)","funders":"","keywords":"Chemistry; Biochemistry; Cell biology; Biology","score_opus":0.016642884497826596,"score_gpt":0.2420099067576386,"score_spread":0.22536702225981198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994729367","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9873439,0.0048408923,0.005735854,0.00006894611,0.000028712082,0.00008290427,0.0007229692,0.00019450212,0.0009812725],"genre_scores_gemma":[0.9743978,0.004853825,0.011232663,0.00010201281,0.00005635531,0.00013099953,0.0032416082,0.000029588437,0.005955317],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991727,0.000006565397,0.0000073241035,0.000026720929,0.00002718698,0.000014937994],"domain_scores_gemma":[0.99971944,0.0000144091355,0.00014468905,0.000013850867,0.00004351294,0.000064104606],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012419598,0.0006871789,0.00027252903,0.00035408494,0.00021057524,0.0002786182,0.00014372879,0.00020482032,0.0005675347],"category_scores_gemma":[0.00015083454,0.00011624942,0.00027909968,0.00029688943,0.00023209413,0.00027353485,0.00022560147,0.00026960045,0.00040284818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011481341,0.000020606183,0.0039743916,0.00008794474,0.00002265243,0.0003952282,0.00006177208,0.000058503818,0.98636615,0.00008554451,0.00013223212,0.008680178],"study_design_scores_gemma":[0.00007042778,0.0016350675,0.2806252,0.00005781684,0.00013006457,0.013632484,0.00031327945,0.0016521385,0.6641067,0.00063731644,0.037097085,0.000042346328],"about_ca_topic_score_codex":0.00030047193,"about_ca_topic_score_gemma":0.00022593104,"teacher_disagreement_score":0.0006871789,"about_ca_system_score_codex":0.00019585801,"about_ca_system_score_gemma":0.00016361347,"threshold_uncertainty_score":0.0018985868},"labels":[],"label_agreement":null},{"id":"W1994912338","doi":"10.1152/ajpheart.01044.2007","title":"Important role of p38 MAP kinase/NF-κB signaling pathway in the sepsis-induced conversion of cardiac myocytes to a proinflammatory phenotype","year":2007,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute","funders":"","keywords":"Proinflammatory cytokine; Phenotype; p38 mitogen-activated protein kinases; Cell biology; Signal transduction; Sepsis; NF-κB; Myocyte; Mitogen-activated protein kinase; Kinase; Cancer research; Biology; Inflammation; Protein kinase A; Immunology; Gene; Genetics","score_opus":0.007791354002651812,"score_gpt":0.2342082536383038,"score_spread":0.22641689963565198,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1994912338","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738442,0.015094164,0.0073300954,0.00045293715,0.00014055727,0.000082039674,0.00041721,0.00011209837,0.0025266],"genre_scores_gemma":[0.9902086,0.0041326988,0.003026246,0.00007406664,0.00004118841,0.00011303597,0.00028779893,0.000010029815,0.002106292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998627,0.000033881945,0.00001207781,0.000027897358,0.000027083332,0.000036459278],"domain_scores_gemma":[0.9999186,0.0000074339764,0.000024793893,0.0000065592353,0.0000122742995,0.000030341169],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023642868,0.0006933338,0.00024799944,0.00023454693,0.00026424843,0.00024030262,0.00014699913,0.00027770537,0.001483603],"category_scores_gemma":[0.00012540075,0.00016421113,0.0003299504,0.00009488838,0.00025861003,0.00035712993,0.00022714795,0.0006879324,0.00036148768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004828077,0.00009350086,0.0003238181,0.000115863404,0.0000063658294,0.0002831525,0.000044123313,0.000064825224,0.9962537,0.00015075681,0.000062398256,0.002118595],"study_design_scores_gemma":[0.00021322827,0.0019871357,0.037587922,0.00007310824,0.000070668764,0.002280673,0.00028945084,0.0030333984,0.9474112,0.00093945744,0.006092752,0.000021035865],"about_ca_topic_score_codex":0.00015341678,"about_ca_topic_score_gemma":0.00021188233,"teacher_disagreement_score":0.001483603,"about_ca_system_score_codex":0.00018265288,"about_ca_system_score_gemma":0.00037190964,"threshold_uncertainty_score":0.0049631},"labels":[],"label_agreement":null},{"id":"W1995213608","doi":"10.1385/criai:20:1:27","title":"Signal-Transduction Defects in T cells","year":2001,"lang":"en","type":"review","venue":"Clinical Reviews in Allergy & Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"Medical Research Council","keywords":"Signal transduction; Phenotype; Biology; Function (biology); Cell biology; Transduction (biophysics); Receptor; Immunology; Computational biology; Genetics; Gene","score_opus":0.08571837274694885,"score_gpt":0.39357313280440037,"score_spread":0.3078547600574515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995213608","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0005840397,0.9949772,0.00094193546,0.00047819008,0.0011479845,0.000011135431,0.000039296952,0.000052757074,0.0017674475],"genre_scores_gemma":[0.0030422995,0.9928154,0.00078711956,0.00052856776,0.0006378986,0.000023378287,0.000095450785,0.0000063128145,0.0020635803],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997316,0.000041239946,0.000036450776,0.00004879835,0.000110031724,0.00003187876],"domain_scores_gemma":[0.99974245,0.00011732865,0.000035740723,0.000013135718,0.000062526,0.000028802737],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006111862,0.0016510959,0.0016434251,0.0013431247,0.00028414818,0.0009973581,0.0012848012,0.0016629741,0.0027566315],"category_scores_gemma":[0.00053905504,0.00035885413,0.0004498385,0.0012886659,0.00091316126,0.0008549388,0.00054310326,0.002075722,0.0033315953],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036489512,0.0001350564,0.00035148626,0.0073701735,0.00008115631,0.0017994525,0.0000533061,0.00053615705,0.05214437,0.0061858105,0.04270179,0.88827634],"study_design_scores_gemma":[0.000102013844,0.00017369862,0.0014361899,0.0013131013,0.00015556307,0.006268711,0.000058807484,0.00023041434,0.017259734,0.004242678,0.9687288,0.00003029859],"about_ca_topic_score_codex":0.00045517983,"about_ca_topic_score_gemma":0.0005238251,"teacher_disagreement_score":0.0027566315,"about_ca_system_score_codex":0.00065947097,"about_ca_system_score_gemma":0.0005524413,"threshold_uncertainty_score":0.009221852},"labels":[],"label_agreement":null},{"id":"W1995727827","doi":"10.1371/journal.pone.0095471","title":"RCAN1 Overexpression Exacerbates Calcium Overloading-Induced Neuronal Apoptosis","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Calcineurin; NFAT; Cell biology; Downregulation and upregulation; Biology; Calcium signaling; Apoptosis; Gene isoform; Calcium; Regulator; Signal transduction; Neuroscience; Internal medicine; Medicine; Biochemistry; Gene; Transplantation","score_opus":0.04372261424541377,"score_gpt":0.24441705382529266,"score_spread":0.2006944395798789,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995727827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997417,0.0011591034,0.0005635381,0.0000929754,0.000033417055,0.00001694421,0.000118211676,0.000051393854,0.0005474697],"genre_scores_gemma":[0.9951014,0.001379562,0.0008711739,0.00005832974,0.00001649105,0.000046110992,0.00029644553,0.0000129376185,0.0022175976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985194,0.000024545454,0.000015067643,0.00003313742,0.000030004448,0.000045329783],"domain_scores_gemma":[0.999874,0.000016725095,0.000041105708,0.000013962591,0.000015244357,0.00003897478],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013767407,0.0005193779,0.00043157142,0.00038418203,0.00020211074,0.00026512108,0.0002852834,0.0003475197,0.0014098401],"category_scores_gemma":[0.0001340804,0.00016995844,0.00023914494,0.0001810414,0.00028149947,0.0002382512,0.00026751088,0.00063720066,0.00024369595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037880562,0.000059284583,0.00029214474,0.00005451924,0.000008430397,0.00013654068,0.000019292866,0.00003794781,0.99799335,0.00005642271,0.0000582932,0.0009049825],"study_design_scores_gemma":[0.000070662914,0.0009419675,0.011575701,0.000016170083,0.00008234572,0.0006754072,0.00008385909,0.00090708496,0.9824949,0.00016283475,0.0029770252,0.000012128019],"about_ca_topic_score_codex":0.00049577525,"about_ca_topic_score_gemma":0.00095233467,"teacher_disagreement_score":0.0014098401,"about_ca_system_score_codex":0.0003527803,"about_ca_system_score_gemma":0.00022681121,"threshold_uncertainty_score":0.0047163367},"labels":[],"label_agreement":null},{"id":"W1995731540","doi":"10.1139/o10-137","title":"Effect of FKBP65, a putative elastin chaperone, on the coacervation of tropoelastin in vitro","year":2010,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Coacervate; Elastin; Tropoelastin; Endoplasmic reticulum; In vitro; Chemistry; Biophysics; Protein disulfide-isomerase; Chaperone (clinical); Biochemistry; In vivo; Molecular biology; Cell biology; Biology","score_opus":0.005065938888635228,"score_gpt":0.23290503125615367,"score_spread":0.22783909236751843,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995731540","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99510634,0.0016144922,0.0018397189,0.00007532804,0.00005069367,0.000030649306,0.000248891,0.000068184374,0.0009657062],"genre_scores_gemma":[0.9934009,0.00079273013,0.0030720208,0.00008338765,0.000017897513,0.000031227275,0.0006006562,0.00005246909,0.0019487634],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951196,0.00014097673,0.00004947706,0.00008683825,0.00008395144,0.00012683593],"domain_scores_gemma":[0.99958223,0.0001224627,0.000077332224,0.00005001741,0.00006210897,0.00010584204],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032750782,0.0007402072,0.00070714456,0.00018979052,0.00021178294,0.00033953754,0.00023949886,0.00032864785,0.00084482227],"category_scores_gemma":[0.00039903313,0.00020751417,0.00047492626,0.0003068302,0.00021999449,0.00021488221,0.0004155332,0.00065143703,0.0005090289],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024060353,0.00006808251,0.00008782687,0.000042533287,0.000012600364,0.000036999052,0.000036471214,0.00010294436,0.99856985,0.000014501961,0.000037403177,0.00075019925],"study_design_scores_gemma":[0.000007358341,0.0002585515,0.0010515684,0.000004191661,0.000011055569,0.000040390834,0.000014836146,0.00054881844,0.9975164,0.0000044010208,0.00053606386,0.000006324555],"about_ca_topic_score_codex":0.0019862612,"about_ca_topic_score_gemma":0.0018953381,"teacher_disagreement_score":0.0019862612,"about_ca_system_score_codex":0.00030006914,"about_ca_system_score_gemma":0.0002432514,"threshold_uncertainty_score":0.0039494038},"labels":[],"label_agreement":null},{"id":"W1995950455","doi":"10.1074/jbc.m105445200","title":"Nerve Activity-dependent Modulation of Calcineurin Signaling in Adult Fast and Slow Skeletal Muscle Fibers","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Laurentian University; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"Calcineurin; Skeletal muscle; Modulation (music); Skeletal Muscle Fibers; Neuroscience; Chemistry; Cell biology; Anatomy; Biology; Internal medicine; Medicine; Physics","score_opus":0.017056175100703452,"score_gpt":0.2548069195173539,"score_spread":0.23775074441665045,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1995950455","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979965,0.0008932814,0.00069073006,0.000010697858,0.0000043807936,0.0000060696543,0.00006137557,0.000007789808,0.0003290435],"genre_scores_gemma":[0.9968779,0.00068973016,0.0010364726,0.000015220027,0.000006803852,0.000017556344,0.00018353792,0.0000069919347,0.0011657794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988806,0.00001596685,0.000011475031,0.000029648321,0.00003136906,0.000023488581],"domain_scores_gemma":[0.99988115,0.00002686056,0.000028784105,0.000013254124,0.000013725077,0.000036252677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016159496,0.00016717704,0.00015615528,0.00014493299,0.000095779826,0.00021827224,0.00013490887,0.00013452991,0.00068612926],"category_scores_gemma":[0.00017506538,0.000074233576,0.00012223123,0.000077253,0.00017461642,0.0002590925,0.00018633553,0.00025439373,0.00012894796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008780988,0.000007204135,0.00037414042,0.000012244565,0.0000014234705,0.000014918164,0.000008236377,0.000015182252,0.99876034,0.000019929668,0.0000020426007,0.0006964186],"study_design_scores_gemma":[0.00001876121,0.00072019594,0.056842145,0.000008094284,0.000015557358,0.00021968651,0.00004897103,0.0010486396,0.94023,0.00007664322,0.0007663354,0.000004971131],"about_ca_topic_score_codex":0.00035542692,"about_ca_topic_score_gemma":0.001194603,"teacher_disagreement_score":0.00068612926,"about_ca_system_score_codex":0.00017310123,"about_ca_system_score_gemma":0.000085424996,"threshold_uncertainty_score":0.0022953749},"labels":[],"label_agreement":null},{"id":"W1996464103","doi":"10.1016/j.jmb.2004.12.034","title":"The Multifunctional Nuclear Protein p54nrb is Multiphosphorylated in Mitosis and Interacts with the Mitotic Regulator Pin1","year":2005,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"PIN1; Cyclin-dependent kinase 1; Chemistry; Mitosis; Prolyl isomerase; Molecular biology; Nuclear protein; Phosphorylation; Cell biology; Peptidylprolyl isomerase; Protein phosphorylation; Epitope; Cyclin B1; Biochemistry; Biology; Protein kinase A; Cell cycle; Antigen; Transcription factor; Isomerase; Genetics","score_opus":0.00428045284714254,"score_gpt":0.22636566101402864,"score_spread":0.2220852081668861,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996464103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883641,0.0059654936,0.0026780565,0.00024354026,0.00006547493,0.0000065131435,0.0001920197,0.00012841566,0.0023563358],"genre_scores_gemma":[0.9945353,0.0010687326,0.0010805367,0.00006985673,0.000017556262,0.000008540692,0.000490658,0.00003361443,0.002695215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998203,0.000017619906,0.000008696463,0.00005895626,0.000044692806,0.000049817696],"domain_scores_gemma":[0.9998498,0.0000132513815,0.000051809962,0.000014311363,0.000014262421,0.000056410587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018794664,0.00040915166,0.0003576848,0.00035477424,0.00054328603,0.00052842,0.00030983443,0.00040272836,0.0019184174],"category_scores_gemma":[0.0002717447,0.00039680567,0.0003060131,0.0001857048,0.00032430442,0.00045072098,0.00053483737,0.00043636042,0.0014969134],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018259147,0.0000071282875,0.00095810054,0.000034069777,0.000010775902,0.0002444472,0.0000121123685,0.00005556715,0.99669814,0.00020506281,0.00016515143,0.0014268362],"study_design_scores_gemma":[0.00007021603,0.00020143099,0.066163294,0.000024726072,0.00005353351,0.0052127577,0.00011221399,0.0029269252,0.9139123,0.0005742658,0.010717209,0.000031276217],"about_ca_topic_score_codex":0.0007634189,"about_ca_topic_score_gemma":0.0014437533,"teacher_disagreement_score":0.0019184174,"about_ca_system_score_codex":0.00065544737,"about_ca_system_score_gemma":0.00015213613,"threshold_uncertainty_score":0.0064176917},"labels":[],"label_agreement":null},{"id":"W1996817878","doi":"10.1007/s11010-005-3699-3","title":"Akt signaling pathway in pacing-induced heart failure","year":2005,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Heart failure; Protein kinase B; Oxidative stress; Internal medicine; Endocrinology; Medicine; Oxidative phosphorylation; Apoptosis; PI3K/AKT/mTOR pathway; Signal transduction; Biology; Cell biology; Biochemistry","score_opus":0.006015160255787218,"score_gpt":0.2124245755667038,"score_spread":0.20640941531091658,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1996817878","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9842892,0.0077625485,0.0023243548,0.00071717077,0.00020892078,0.00003452755,0.00025448448,0.00007248839,0.0043362672],"genre_scores_gemma":[0.99643517,0.0016807675,0.00046600372,0.000111325535,0.000046728164,0.000034298773,0.00014011947,0.000005885499,0.0010797941],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999106,0.000031838037,0.000008425628,0.000010717006,0.000016534568,0.00002180125],"domain_scores_gemma":[0.9999323,0.000016149434,0.0000150785,0.000008386424,0.0000050834087,0.0000230168],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028324858,0.000437462,0.00020965228,0.00021561734,0.00028421538,0.00033902598,0.00023094956,0.00040014254,0.0015272697],"category_scores_gemma":[0.00020814946,0.00024317628,0.00021058989,0.00013833096,0.00027785634,0.0002633955,0.00024335997,0.00092987163,0.00022130263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.008437903,0.00020147683,0.0024088728,0.00020392741,0.00003752332,0.0020062227,0.000065912594,0.000723491,0.9761544,0.0028209307,0.0004711383,0.0064683184],"study_design_scores_gemma":[0.0015741007,0.0057528345,0.112731405,0.0000969367,0.0004016233,0.011471491,0.0002446963,0.008580552,0.8432955,0.005842718,0.009955703,0.00005246311],"about_ca_topic_score_codex":0.00018957746,"about_ca_topic_score_gemma":0.00019631625,"teacher_disagreement_score":0.0015272697,"about_ca_system_score_codex":0.00031860406,"about_ca_system_score_gemma":0.000278466,"threshold_uncertainty_score":0.0051092505},"labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low"},{"model":"gpt","categories":[],"domain":null,"study_design":"bench_or_experimental","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"high"}],"label_agreement":"agree"},{"id":"W1997877101","doi":"10.1002/stem.85","title":"Embryonic Stem Cell-Derived Cardiomyogenesis: A Novel Role for Calreticulin as a Regulator","year":2009,"lang":"en","type":"article","venue":"Stem Cells","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Calreticulin; Biology; Endoplasmic reticulum; Cell biology; Actin; Molecular biology","score_opus":0.009898348413515796,"score_gpt":0.22551787309430912,"score_spread":0.21561952468079332,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1997877101","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9688649,0.00940624,0.01639377,0.00036521672,0.00009639873,0.000047148314,0.0005966529,0.0002257704,0.004003831],"genre_scores_gemma":[0.98095936,0.005378915,0.0076699518,0.00019179579,0.000039590737,0.000036550173,0.00088251475,0.00005082853,0.0047904295],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992836,0.000005646149,0.000007761301,0.00001828782,0.00002654994,0.000013350339],"domain_scores_gemma":[0.9999368,0.000009383198,0.0000149846155,0.0000081705075,0.000010120328,0.000020451054],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010633382,0.00034472745,0.00016764538,0.00019343714,0.00011017475,0.00025768313,0.00015494366,0.00018822767,0.0003911313],"category_scores_gemma":[0.000066511595,0.00011831995,0.00016269545,0.000106830295,0.00021384105,0.00014048601,0.00022191223,0.00034039447,0.00016822746],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015506988,0.0000026601585,0.00028175308,0.00001776763,0.0000018663827,0.00011790307,0.000008697438,0.00001751392,0.99816304,0.00015815771,0.000015638972,0.0011995318],"study_design_scores_gemma":[0.00001648529,0.00009661059,0.024478089,0.0000116222345,0.00002746554,0.0012604194,0.000027680877,0.0008314969,0.9654107,0.00016463631,0.0076690996,0.00000563369],"about_ca_topic_score_codex":0.00028083895,"about_ca_topic_score_gemma":0.00069713633,"teacher_disagreement_score":0.0003911313,"about_ca_system_score_codex":0.00027428204,"about_ca_system_score_gemma":0.00018608838,"threshold_uncertainty_score":0.0019900799},"labels":[],"label_agreement":null},{"id":"W1998095124","doi":"10.1161/01.cir.0000014211.47830.4d","title":"Inhibition of Calcineurin and Sarcolemmal Ca <sup>2+</sup> Influx Protects Cardiac Morphology and Ventricular Function in K <sub>v</sub> 4.2N Transgenic Mice","year":2002,"lang":"en","type":"article","venue":"Circulation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Contractility; Calcineurin; Internal medicine; Endocrinology; Phospholamban; Medicine; SERCA; Endoplasmic reticulum; Heart failure; Cardiac function curve; Myocyte; Calcium; Genetically modified mouse; Transgene; ATPase; Biology; Cell biology; Transplantation; Biochemistry; Enzyme","score_opus":0.011362791982063431,"score_gpt":0.20533422778050295,"score_spread":0.1939714357984395,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998095124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99662614,0.00051667105,0.0015068846,0.000090485955,0.000026515614,0.000039072635,0.00035668444,0.00014514616,0.0006923549],"genre_scores_gemma":[0.99005604,0.0005442779,0.0028540625,0.00008301704,0.000029588617,0.00015302496,0.00068385067,0.000100347315,0.005495783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997991,0.00002491408,0.00003226142,0.00004665367,0.00005174921,0.000045315806],"domain_scores_gemma":[0.999519,0.000031496038,0.0002407971,0.000032703785,0.00003268349,0.0001433898],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022334927,0.00078660605,0.00042214876,0.0004519422,0.00023583768,0.00037954876,0.0005848093,0.0006321721,0.0016880238],"category_scores_gemma":[0.0001864226,0.00036347384,0.0003127452,0.00014067435,0.00057783833,0.00042766423,0.00028577913,0.00067232305,0.00045693704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043095706,0.00006430348,0.00020339321,0.00002523495,0.0000068234663,0.00006386863,0.000013910276,0.00003479024,0.9986331,0.000061132996,0.000026287762,0.00043625358],"study_design_scores_gemma":[0.0003318142,0.0017389444,0.010725118,0.00003308803,0.00007108777,0.0009287881,0.00007950648,0.0013993575,0.98250663,0.00014709178,0.0020219567,0.000016684975],"about_ca_topic_score_codex":0.0006284527,"about_ca_topic_score_gemma":0.0012787818,"teacher_disagreement_score":0.0016880238,"about_ca_system_score_codex":0.0004913953,"about_ca_system_score_gemma":0.00034226765,"threshold_uncertainty_score":0.0056470633},"labels":[],"label_agreement":null},{"id":"W1998099484","doi":"10.1074/jbc.m408658200","title":"Modulation of Secretory Granule-targeting Efficiency by Cis and Trans Compounding of Sorting Signals","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"","keywords":"Compounding; Granule (geology); Sorting; Modulation (music); Chemistry; Cell biology; Biophysics; Computer science; Materials science; Nanotechnology; Biology; Physics; Acoustics; Composite material; Algorithm","score_opus":0.016585919296169354,"score_gpt":0.25309560192082997,"score_spread":0.23650968262466063,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998099484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966388,0.000631731,0.0016969343,0.00004007143,0.00001405855,0.000022438047,0.000059479666,0.00003581427,0.00086065364],"genre_scores_gemma":[0.9966344,0.0004196373,0.0019634757,0.000025267009,0.000008304125,0.000016254253,0.000109418565,0.000017663388,0.0008056444],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99956745,0.00012117393,0.000053205316,0.00006926666,0.000104174425,0.00008467254],"domain_scores_gemma":[0.99950254,0.0001594006,0.00011374392,0.00006796579,0.00004325557,0.00011299435],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045264,0.00045396184,0.0004039195,0.00020528366,0.00011302154,0.0004807642,0.0001980244,0.00027914252,0.0010639243],"category_scores_gemma":[0.00036344954,0.00018363008,0.00025990405,0.00015414745,0.00029172585,0.0003076888,0.0002968597,0.00067596586,0.0003592072],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017587662,0.000014372102,0.00007941909,0.000015419942,0.0000037568248,0.000018922425,0.0000046090727,0.000055420467,0.99903667,0.00006976474,0.0000046464584,0.00052105007],"study_design_scores_gemma":[0.000014420589,0.00022018666,0.00060033693,0.0000016511,0.000011768193,0.00010226368,0.000008287099,0.0005081463,0.99818295,0.000015474987,0.0003320768,0.0000023146088],"about_ca_topic_score_codex":0.00018265044,"about_ca_topic_score_gemma":0.00023678783,"teacher_disagreement_score":0.0010639243,"about_ca_system_score_codex":0.00028487595,"about_ca_system_score_gemma":0.00022461438,"threshold_uncertainty_score":0.0035591722},"labels":[],"label_agreement":null},{"id":"W1998203607","doi":"10.1139/y10-087","title":"Sequential alterations in Akt, GSK3β, and calcineurin signalling in the mouse left ventricle after thoracic aortic constriction","year":2010,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Ministère de l'Enseignement Supérieur et de la Recherche; Institut National de la Santé et de la Recherche Médicale","keywords":"Protein kinase B; Calcineurin; Muscle hypertrophy; Downregulation and upregulation; Internal medicine; Ventricle; Pressure overload; Medicine; Endocrinology; GSK-3; Left ventricular hypertrophy; Heart failure; Kinase; Cardiology; Chemistry; Phosphorylation; Cardiac hypertrophy; Biochemistry; Transplantation","score_opus":0.011454723170733538,"score_gpt":0.28664503791776264,"score_spread":0.2751903147470291,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998203607","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963961,0.001704821,0.0007691386,0.00007207677,0.00003302503,0.00002139177,0.00034373545,0.000060638722,0.00059916347],"genre_scores_gemma":[0.9930214,0.0012730063,0.0011401168,0.00010960936,0.000023398552,0.000103718376,0.00065636134,0.00003376098,0.0036386084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978393,0.000020485168,0.000019889474,0.000055913915,0.000044781715,0.00007492178],"domain_scores_gemma":[0.99975175,0.000018928207,0.0000893745,0.000020110385,0.000016416561,0.000103421546],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027986095,0.0004244644,0.00039067687,0.00067136966,0.00021981145,0.00046967372,0.00023331329,0.00050038187,0.0010304016],"category_scores_gemma":[0.00013087383,0.0004289604,0.0005141586,0.00025494175,0.00062650966,0.0005129449,0.00022971554,0.001389233,0.00038831146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00094699796,0.00008133244,0.00057950855,0.000031479387,0.0000073330134,0.00009809153,0.000046372596,0.000040747764,0.9973009,0.00007977417,0.00002999736,0.00075747666],"study_design_scores_gemma":[0.00020798796,0.0021806424,0.06042676,0.00002863515,0.00007988486,0.00044105694,0.00020382996,0.0010053058,0.93376356,0.00026016976,0.0013763991,0.000025747055],"about_ca_topic_score_codex":0.00079672766,"about_ca_topic_score_gemma":0.0016063398,"teacher_disagreement_score":0.0010304016,"about_ca_system_score_codex":0.0004629241,"about_ca_system_score_gemma":0.00028105083,"threshold_uncertainty_score":0.0034470558},"labels":[],"label_agreement":null},{"id":"W1998956779","doi":"10.1016/s0969-9961(02)00020-7","title":"Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice","year":2003,"lang":"en","type":"article","venue":"Neurobiology of Disease","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"XIAP; MPTP; Neurotoxicity; Neurodegeneration; Dopaminergic; Genetically modified mouse; Dopamine; Neurotoxin; Transgene; Neuroscience; Biology; Pharmacology; Programmed cell death; Medicine; Disease; Internal medicine; Apoptosis; Toxicity; Endocrinology; Biochemistry; Gene; Caspase","score_opus":0.020353075202036476,"score_gpt":0.25364236242690497,"score_spread":0.2332892872248685,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1998956779","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876129,0.0009526385,0.005733649,0.00062493555,0.000113883594,0.00007676813,0.0022062284,0.0006919445,0.001987108],"genre_scores_gemma":[0.9745662,0.001468438,0.004769041,0.00016699937,0.00005299361,0.00022633378,0.0017275255,0.00022213164,0.016800398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963915,0.000042185842,0.00004924139,0.000092475646,0.000101257276,0.00007562182],"domain_scores_gemma":[0.99924564,0.00007545449,0.0002768256,0.000081145314,0.000071199596,0.0002497207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030035852,0.0012467139,0.00062813354,0.0018571492,0.00042951276,0.00057715416,0.00079514587,0.0010305453,0.003920201],"category_scores_gemma":[0.00037235007,0.0004809888,0.0005816682,0.00046866635,0.0011370064,0.00074247783,0.00044026304,0.0023863942,0.0007811412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038138166,0.00014635234,0.00016410767,0.00004800802,0.000018843579,0.00015818681,0.00005200756,0.00013703108,0.99733233,0.00024654047,0.00011171071,0.0012035975],"study_design_scores_gemma":[0.00014943206,0.00071337895,0.0064460654,0.000037893886,0.0000900345,0.00084866537,0.00010178959,0.0026924643,0.98599374,0.0003776536,0.0025211002,0.00002779815],"about_ca_topic_score_codex":0.0020539244,"about_ca_topic_score_gemma":0.0030045244,"teacher_disagreement_score":0.003920201,"about_ca_system_score_codex":0.0006909964,"about_ca_system_score_gemma":0.00044481098,"threshold_uncertainty_score":0.013114393},"labels":[],"label_agreement":null},{"id":"W1999285273","doi":"10.1016/j.cardiores.2004.08.005","title":"Heart block in mice overexpressing calcineurin but not NF-AT3","year":2004,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Foothills Medical Centre; University of Calgary","funders":"","keywords":"Calcineurin; Internal medicine; Medicine; Cardiology; Ventricular tachycardia; Tachycardia; Refractory period; Atrioventricular block; Muscle hypertrophy; Transplantation","score_opus":0.05764306639611595,"score_gpt":0.3398529422917234,"score_spread":0.2822098758956075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999285273","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949163,0.0005808413,0.0026594338,0.00011597123,0.000051805826,0.000056418296,0.00062428194,0.00020603642,0.0007888589],"genre_scores_gemma":[0.98906004,0.0006964997,0.003152953,0.000114493574,0.000038659295,0.00019594836,0.0011701091,0.00018111723,0.0053901817],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996253,0.00004262704,0.000051856405,0.00012007863,0.000089977286,0.00007008821],"domain_scores_gemma":[0.9989631,0.00013149466,0.0005219648,0.000063475905,0.000045143737,0.00027482212],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003855748,0.000984173,0.00044082222,0.00090622634,0.0004057772,0.0005180854,0.00047078333,0.00078668405,0.0034926063],"category_scores_gemma":[0.00031178628,0.00039442012,0.0006452798,0.0002875164,0.00081672875,0.0005459431,0.00034642316,0.0011103087,0.00063370285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002927471,0.00005305793,0.00031138587,0.000027251885,0.000010364295,0.00018364252,0.000035343863,0.00004550511,0.99847394,0.00011831517,0.000023144172,0.00042545536],"study_design_scores_gemma":[0.00050367526,0.003282313,0.035047315,0.00009138537,0.00017634792,0.0052411766,0.00024645124,0.00306836,0.94819736,0.00038081888,0.0037167685,0.000048072736],"about_ca_topic_score_codex":0.00075548404,"about_ca_topic_score_gemma":0.0011252809,"teacher_disagreement_score":0.0034926063,"about_ca_system_score_codex":0.0004566159,"about_ca_system_score_gemma":0.00026909917,"threshold_uncertainty_score":0.011683881},"labels":[],"label_agreement":null},{"id":"W1999371740","doi":"10.1186/1471-2407-9-251","title":"Cyclophilin C-associated protein (CyCAP) knock-out mice spontaneously develop colonic mucosal hyperplasia and exaggerated tumorigenesis after treatment with carcinogen azoxymethane1","year":2009,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; Royal University Hospital","funders":"National Cancer Institute; Royal University Hospital Foundation; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Azoxymethane; Crypt; Hyperplasia; Dysplasia; Pathology; Carcinogenesis; Cyclin D1; Intestinal mucosa; Aberrant crypt foci; Immunohistochemistry; Medicine; Biology; Cancer research; Colorectal cancer; Internal medicine; Cancer; Cell cycle","score_opus":0.011867398570087161,"score_gpt":0.24437403612586095,"score_spread":0.23250663755577378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999371740","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98892295,0.0011084956,0.0034038115,0.00030985597,0.000107542255,0.00012190842,0.0029975187,0.00044137318,0.0025866262],"genre_scores_gemma":[0.9658793,0.001404848,0.004032309,0.0002514165,0.00006967869,0.00035738878,0.0033229815,0.00024041405,0.024441766],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995578,0.00004033466,0.00003518414,0.00013748965,0.00012932942,0.00009987143],"domain_scores_gemma":[0.99920696,0.00007479089,0.0002934749,0.000072846655,0.00004461328,0.00030722632],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026158083,0.0010942119,0.0004978869,0.0011372989,0.0004213041,0.0005018026,0.0003966771,0.0008969397,0.0064054383],"category_scores_gemma":[0.00018084246,0.0005635072,0.00047217004,0.00037949329,0.0006693294,0.00041954187,0.00037831784,0.0016808218,0.0013899818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029548575,0.0001334597,0.0003839736,0.00005471684,0.000010336072,0.00024812063,0.00002006886,0.000046459194,0.99792624,0.00012182058,0.0001462455,0.00061297923],"study_design_scores_gemma":[0.0001347225,0.0019765596,0.020601213,0.000049311573,0.00006729547,0.0034167997,0.00012778841,0.0014916767,0.96607447,0.00019130368,0.005844254,0.000024578116],"about_ca_topic_score_codex":0.0007538882,"about_ca_topic_score_gemma":0.001519122,"teacher_disagreement_score":0.0064054383,"about_ca_system_score_codex":0.00044856843,"about_ca_system_score_gemma":0.00035167774,"threshold_uncertainty_score":0.021428347},"labels":[],"label_agreement":null},{"id":"W1999425838","doi":"10.1074/jbc.c800087200","title":"Interleukin-3 (IL-3)-induced c-fos Activation Is Modulated by Gab2-Calcineurin Interaction","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Calcineurin; Cell biology; Phosphatase; Protein kinase B; Chemistry; Stimulation; Cell growth; Cytokine; Signal transduction; Receptor; Biology; Phosphorylation; Neuroscience; Biochemistry; Immunology; Transplantation; Internal medicine; Medicine","score_opus":0.04073309815782018,"score_gpt":0.2793298823492776,"score_spread":0.2385967841914574,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999425838","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9913516,0.00423923,0.0016628394,0.00021563855,0.000059227128,0.000025753541,0.00020703294,0.00004833295,0.0021904134],"genre_scores_gemma":[0.99452424,0.0021726142,0.0013921928,0.00010443486,0.000016770864,0.00004806609,0.00026472198,0.000011034923,0.0014659392],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998729,0.000018160476,0.0000102163685,0.000021159021,0.00003164704,0.000045801436],"domain_scores_gemma":[0.9999244,0.000010004255,0.000028784856,0.000004731808,0.000010778418,0.000021338845],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010621414,0.0003670447,0.00014242099,0.00022365294,0.00022044446,0.00026085906,0.00013995587,0.00021267899,0.0010864234],"category_scores_gemma":[0.00010783681,0.00011015479,0.00033271022,0.00015907624,0.00025393188,0.00020338586,0.00025467062,0.00054318743,0.0001722725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015062859,0.000024100731,0.00028854993,0.00005351557,0.000006369861,0.00011910441,0.000027375183,0.000047978552,0.99823546,0.0001632017,0.000052208572,0.00083134486],"study_design_scores_gemma":[0.00007597604,0.00027158734,0.029097416,0.000024751322,0.00003542952,0.00067887607,0.0001023622,0.002173995,0.9624225,0.00026261763,0.004841134,0.000013404763],"about_ca_topic_score_codex":0.0009653327,"about_ca_topic_score_gemma":0.0019899039,"teacher_disagreement_score":0.0010864234,"about_ca_system_score_codex":0.0003863502,"about_ca_system_score_gemma":0.00027388142,"threshold_uncertainty_score":0.0036343932},"labels":[],"label_agreement":null},{"id":"W2000780715","doi":"10.1016/j.jmb.2007.08.051","title":"Structural, Biochemical, and in Vivo Characterization of the First Virally Encoded Cyclophilin from the Mimivirus","year":2007,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Cyclophilin A; Biology; Cyclophilin; Virology; Cis-trans-Isomerases; Peptidylprolyl isomerase; Virus; Cypa; Isomerase; Gene; Molecular biology; Genetics","score_opus":0.006752856614496901,"score_gpt":0.24171773255715637,"score_spread":0.23496487594265947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000780715","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966413,0.00040142005,0.0015100098,0.00016508027,0.000023321749,0.000011877054,0.00040325025,0.000021654358,0.00082213327],"genre_scores_gemma":[0.9941227,0.0002857305,0.0018066312,0.00006900864,0.000011368137,0.000010298759,0.0017360429,0.000023364888,0.0019348498],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993503,0.000012354549,0.000005915867,0.000012796039,0.000016244814,0.00001765717],"domain_scores_gemma":[0.9998534,0.00003206909,0.00003169635,0.000018668274,0.000016557575,0.000047567293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001509695,0.00032907553,0.00017685877,0.00022242843,0.00029877998,0.0004394691,0.00023472928,0.000275118,0.00089185854],"category_scores_gemma":[0.00021377968,0.0001645988,0.00025431346,0.00017595853,0.00024409826,0.00022668431,0.00019469987,0.0007418246,0.00033499094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008289447,0.000018385004,0.00025956516,0.000014504634,0.000004098749,0.000081359234,0.00001835531,0.000119287455,0.998609,0.00030405572,0.000046818495,0.00044172117],"study_design_scores_gemma":[0.000011638969,0.00007823067,0.0058068335,0.0000038546646,0.000016479044,0.00039099692,0.00005012042,0.0012826985,0.9884703,0.00015905239,0.0037241043,0.0000056435606],"about_ca_topic_score_codex":0.001294598,"about_ca_topic_score_gemma":0.0016726053,"teacher_disagreement_score":0.001294598,"about_ca_system_score_codex":0.00078509643,"about_ca_system_score_gemma":0.0002936583,"threshold_uncertainty_score":0.0056962967},"labels":[],"label_agreement":null},{"id":"W2000963638","doi":"10.1007/s002470050735","title":"MRI appearances of hip abnormalities in mucolipidosis, type III","year":2000,"lang":"en","type":"article","venue":"Pediatric Radiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Hospital for Sick Children","funders":"","keywords":"Mucolipidosis; Medicine; Neuroradiology; Etiology; Lysosomal storage disease; Pathology; Magnetic resonance imaging; Radiology; Disease; Neurology; Nuclear magnetic resonance","score_opus":0.007427284483302506,"score_gpt":0.23379802893834806,"score_spread":0.22637074445504554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000963638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96609414,0.0035729446,0.002805545,0.0024005063,0.00010211813,0.00015747192,0.00058626186,0.00024323295,0.024037732],"genre_scores_gemma":[0.9966941,0.0010320233,0.0010736429,0.00031423036,0.00014557916,0.000013866317,0.00011983195,0.000023216175,0.00058349513],"study_design_codex":"case_report","study_design_gemma":"case_report","domain_scores_codex":[0.99980026,0.000025797359,0.000030456227,0.000026126552,0.000045860525,0.000071428025],"domain_scores_gemma":[0.99894315,0.00027566974,0.000231827,0.000057546164,0.00013314802,0.00035865585],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033692838,0.0008607174,0.0004391372,0.0020802082,0.00043754085,0.00044540243,0.0005564279,0.0016001619,0.0021059327],"category_scores_gemma":[0.0033755149,0.00054154044,0.00032120096,0.0009919136,0.00086370617,0.0008076263,0.00046333837,0.0011440373,0.0006058932],"study_design_candidate":"case_report","study_design_consensus":"case_report","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006803071,0.000114359704,0.05086811,0.00016695444,0.000047591315,0.9089268,0.00028642965,0.0006821385,0.027292555,0.0006809114,0.001577286,0.0086765345],"study_design_scores_gemma":[0.000080440695,0.00028683885,0.12029739,0.000058349815,0.00006644333,0.8676092,0.00022567682,0.0012557243,0.008425768,0.00042353082,0.0012425235,0.000028145254],"about_ca_topic_score_codex":0.005836825,"about_ca_topic_score_gemma":0.0028522061,"teacher_disagreement_score":0.005836825,"about_ca_system_score_codex":0.0005094861,"about_ca_system_score_gemma":0.00058664626,"threshold_uncertainty_score":0.01160568},"labels":[],"label_agreement":null},{"id":"W2001368305","doi":"10.1016/j.neurobiolaging.2014.07.029","title":"Amyloid-β precursor protein facilitates the regulator of calcineurin 1-mediated apoptosis by downregulating proteasome subunit α type-5 and proteasome subunit β type-7","year":2014,"lang":"en","type":"article","venue":"Neurobiology of Aging","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Canada Research Chairs","keywords":"Proteasome; Protein subunit; Neurodegeneration; Cell biology; Senile plaques; Biology; Alzheimer's disease; Molecular biology; Biochemistry; Internal medicine; Medicine; Gene; Disease","score_opus":0.008760178754369415,"score_gpt":0.2228438534951327,"score_spread":0.21408367474076329,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001368305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98497075,0.005999516,0.004796903,0.0004212695,0.00019234461,0.000028271383,0.00021116865,0.00023521826,0.0031445604],"genre_scores_gemma":[0.9915888,0.002217783,0.002179484,0.00012584562,0.0000616207,0.0000271079,0.0002468712,0.000044113116,0.0035085084],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997646,0.00004271503,0.000021535834,0.000047832447,0.00006567541,0.000057557245],"domain_scores_gemma":[0.99978274,0.000024868714,0.00006512742,0.000028343222,0.00004385369,0.000055172124],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026979457,0.0004571684,0.0002801944,0.00041391284,0.00031136477,0.00048004987,0.00024997766,0.00025820156,0.0014203854],"category_scores_gemma":[0.0002385374,0.00020579714,0.00039180715,0.00017272893,0.00033488433,0.0004027539,0.00028785077,0.0007576925,0.00041078668],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025976196,0.000049737737,0.00032200146,0.000043515032,0.000012656957,0.00014362037,0.000023798699,0.000039104587,0.9968618,0.0003459251,0.00011180398,0.0017861738],"study_design_scores_gemma":[0.00004382835,0.00027564788,0.010888199,0.000008829905,0.000044977896,0.00060001365,0.000062035004,0.00064057723,0.98266834,0.00039406412,0.004366302,0.000007197637],"about_ca_topic_score_codex":0.0004142105,"about_ca_topic_score_gemma":0.0006505046,"teacher_disagreement_score":0.0014203854,"about_ca_system_score_codex":0.00034845524,"about_ca_system_score_gemma":0.00037267784,"threshold_uncertainty_score":0.0047516227},"labels":[],"label_agreement":null},{"id":"W2001706484","doi":"10.1016/j.bbrc.2011.08.079","title":"RNA polymerase II degradation in response to rapamycin is not mediated through ubiquitylation","year":2011,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian Institutes of Health Research","keywords":"RNA polymerase I; Polymerase; RNA polymerase II; RNA polymerase; Biology; Termination factor; Cell biology; Transcription factor II D; RNA; RNA-dependent RNA polymerase; Saccharomyces cerevisiae; Ubiquitin; Biochemistry; Chemistry; Enzyme; Yeast; Gene; Gene expression","score_opus":0.14012699524507694,"score_gpt":0.3828238268579938,"score_spread":0.24269683161291689,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2001706484","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98665977,0.0066456045,0.0020564916,0.00039643794,0.00026748027,0.000028201086,0.0006071435,0.00020850307,0.0031303898],"genre_scores_gemma":[0.99612457,0.0006535241,0.0006555444,0.000087781504,0.000036414393,0.000017200384,0.0005808165,0.000027784527,0.0018162264],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996482,0.00003532174,0.000047452926,0.00010354821,0.00006290035,0.00010253244],"domain_scores_gemma":[0.9995753,0.000054213437,0.00013072634,0.00010351746,0.00003774435,0.000098453624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030234005,0.0004459067,0.00056673656,0.00031349895,0.00049637695,0.0010006531,0.00024613287,0.0005590322,0.0019448356],"category_scores_gemma":[0.0004348402,0.00043650367,0.000616494,0.00015802855,0.0005673233,0.00059513643,0.0003530165,0.0007021286,0.0009543406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006113177,0.000029641045,0.0005354835,0.00006134321,0.000025082125,0.000110240595,0.000013296038,0.000048764883,0.99672014,0.00023908677,0.0001674926,0.0014381651],"study_design_scores_gemma":[0.000044888577,0.00016456179,0.018237928,0.000011071281,0.000023661634,0.00077028,0.00003812461,0.00079381675,0.97668195,0.00016721975,0.0030510016,0.000015468167],"about_ca_topic_score_codex":0.000690153,"about_ca_topic_score_gemma":0.0012790777,"teacher_disagreement_score":0.0019448356,"about_ca_system_score_codex":0.00062146183,"about_ca_system_score_gemma":0.000358579,"threshold_uncertainty_score":0.006506145},"labels":[],"label_agreement":null},{"id":"W2002616191","doi":"10.1002/cbdv.201100418","title":"Electrochemical Investigations of Tau Protein Phosphorylations and Interactions with Pin1","year":2012,"lang":"en","type":"article","venue":"Chemistry & Biodiversity","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; The Scarborough Hospital; University of Toronto","funders":"","keywords":"PIN1; Chemistry; Phosphorylation; Isomerase; Dielectric spectroscopy; Tau protein; Biophysics; Peptidylprolyl isomerase; Electrochemistry; Biochemistry; Enzyme; Electrode; Alzheimer's disease; Physical chemistry; Biology","score_opus":0.010756964324376833,"score_gpt":0.21136697537940283,"score_spread":0.200610011055026,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2002616191","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9847772,0.0017879901,0.010829846,0.00016264775,0.00003518276,0.000019673651,0.00023416741,0.000085447035,0.0020678223],"genre_scores_gemma":[0.99237156,0.0011471155,0.0044089057,0.000069139154,0.00001836338,0.000033021253,0.00018923788,0.000011256923,0.0017514358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996972,0.000050570463,0.000013238106,0.00006392815,0.00011684622,0.000058328493],"domain_scores_gemma":[0.99980766,0.00008753688,0.000036808582,0.000011402962,0.000034148798,0.000022338865],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024293481,0.00035379475,0.0002508278,0.0002794437,0.0001950451,0.00032809877,0.00038527607,0.0004306045,0.0011991251],"category_scores_gemma":[0.00055223465,0.00019458684,0.00014892848,0.00040127613,0.00018526867,0.00033448005,0.00024932902,0.0006738581,0.0002617904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000431231,0.000014532361,0.00023666868,0.000029676621,0.000008361899,0.000041999116,0.0000448396,0.00006585007,0.9979488,0.000079429665,0.000024711704,0.0014620816],"study_design_scores_gemma":[0.0000073804404,0.000113332855,0.003877433,0.000005136541,0.000016263182,0.0002106959,0.00009477962,0.0034657044,0.9911851,0.00010492348,0.000910001,0.000009286937],"about_ca_topic_score_codex":0.0004223112,"about_ca_topic_score_gemma":0.00035915652,"teacher_disagreement_score":0.0011991251,"about_ca_system_score_codex":0.00021728738,"about_ca_system_score_gemma":0.00006702906,"threshold_uncertainty_score":0.004011452},"labels":[],"label_agreement":null},{"id":"W2003368716","doi":"10.1111/j.1365-2559.2006.02559.x","title":"Expression of Endo180 is spatially and temporally regulated during wound healing","year":2006,"lang":"en","type":"article","venue":"Histopathology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Wellcome Trust","keywords":"Wound healing; Immunostaining; Regeneration (biology); Extracellular matrix; Myofibroblast; Cell biology; Connective tissue; Pathology; Fibroblast; Epithelium; Cell migration; Scars; Biology; Chemistry; Cell; Immunohistochemistry; Immunology; Cell culture; Medicine; Fibrosis; Biochemistry","score_opus":0.0073712252836053305,"score_gpt":0.2212089713893349,"score_spread":0.21383774610572956,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003368716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917536,0.0032718845,0.003004157,0.000048136666,0.000016618209,0.000018337407,0.00026840516,0.00005674288,0.0015620411],"genre_scores_gemma":[0.9929854,0.0012818477,0.0022441563,0.000038392674,0.000014712666,0.0000404494,0.00047177187,0.000018150711,0.0029050903],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990106,0.000011014943,0.0000058094292,0.00002874364,0.000026747213,0.0000266454],"domain_scores_gemma":[0.99986506,0.000017475384,0.000060281942,0.000008066003,0.00002348316,0.000025548334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012210995,0.00019505496,0.00017196151,0.00029099526,0.000145114,0.0003529029,0.000111505506,0.00020730175,0.0011849017],"category_scores_gemma":[0.00015787974,0.00015759323,0.00013060593,0.00014210668,0.0002189386,0.00025501882,0.00017960144,0.00030702096,0.0004615291],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015773717,0.0000073312804,0.00083976914,0.000023309694,0.0000019889137,0.00009400726,0.00001626359,0.000011047733,0.99751794,0.000059171125,0.000024737717,0.0012467058],"study_design_scores_gemma":[0.000020129579,0.0004495528,0.13320445,0.000023107572,0.000024683983,0.0013392948,0.00019139129,0.0004014064,0.8583296,0.00021371186,0.005793307,0.000009382538],"about_ca_topic_score_codex":0.00015381856,"about_ca_topic_score_gemma":0.00020341786,"teacher_disagreement_score":0.0011849017,"about_ca_system_score_codex":0.00019586098,"about_ca_system_score_gemma":0.00010024862,"threshold_uncertainty_score":0.0039639473},"labels":[],"label_agreement":null},{"id":"W2003448854","doi":"10.1016/j.saa.2010.09.013","title":"Spectroscopic studies on the irreversible heat-induced structural transition of Pin1","year":2010,"lang":"en","type":"article","venue":"Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Key Technologies Research and Development Program; Sichuan University; Université Laval","keywords":"Transition (genetics); PIN1; Chemistry; Materials science; Biochemistry; Isomerase","score_opus":0.01368518378968667,"score_gpt":0.27982349322442635,"score_spread":0.26613830943473965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003448854","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914419,0.000912162,0.0033212686,0.0001507925,0.000029706682,0.000016801283,0.00019788342,0.00005875543,0.0038707482],"genre_scores_gemma":[0.99794453,0.00030811518,0.00042349237,0.000043786087,0.0000056758945,0.000013590232,0.00019132931,0.000013915527,0.0010555547],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989533,0.000015857404,0.0000025836384,0.000018805076,0.000025068233,0.000042327],"domain_scores_gemma":[0.999803,0.000079032245,0.000051500938,0.000017179449,0.000026541677,0.000022705917],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017678273,0.00024651896,0.00011444103,0.00022395168,0.0003634343,0.00014322312,0.00041930744,0.00024520227,0.004405631],"category_scores_gemma":[0.00045341387,0.00015179734,0.00017382966,0.0002756179,0.00043636977,0.0003066901,0.00024247548,0.0010471577,0.00023147046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012753843,0.0000242442,0.00022902072,0.000062599254,0.000010344281,0.00007270205,0.000087244545,0.00019426193,0.9969811,0.00046236793,0.000103000864,0.0016455922],"study_design_scores_gemma":[0.000008030758,0.000095206095,0.0050146696,0.000006311596,0.000008141262,0.00013519739,0.00006748587,0.001033178,0.99257916,0.000115286864,0.00092792546,0.000009441039],"about_ca_topic_score_codex":0.0008172546,"about_ca_topic_score_gemma":0.0006853702,"teacher_disagreement_score":0.004405631,"about_ca_system_score_codex":0.0002980042,"about_ca_system_score_gemma":0.00012362753,"threshold_uncertainty_score":0.014738262},"labels":[],"label_agreement":null},{"id":"W2003675091","doi":"10.1074/jbc.m110.171728","title":"Synthesis, Maturation, and Trafficking of Human Na+-Dicarboxylate Cotransporter NaDC1 Requires the Chaperone Activity of Cyclophilin B","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Cyclophilin; Calcineurin; Reabsorption; HEK 293 cells; Symporter; Chemistry; Cell biology; Biochemistry; Apical membrane; Biology; Kidney; Transporter; Transplantation; Receptor; Internal medicine; Endocrinology; Membrane","score_opus":0.03570080358484594,"score_gpt":0.253248483976366,"score_spread":0.21754768039152006,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003675091","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99667144,0.00096207793,0.0011145148,0.00012199784,0.000016725384,0.000013658544,0.00030973216,0.000021377387,0.0007684294],"genre_scores_gemma":[0.99576074,0.0006324893,0.001037162,0.0000509407,0.0000071364793,0.000017012138,0.0007573801,0.000013181139,0.0017239025],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992144,0.0000104573055,0.000008474054,0.000023947126,0.000017343593,0.000018291828],"domain_scores_gemma":[0.9999497,0.000009428708,0.000008667507,0.000007613307,0.000007873256,0.000016748805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000876631,0.00010206035,0.00012386944,0.00007460096,0.00014239423,0.00024840434,0.00009444433,0.00013799462,0.00085090974],"category_scores_gemma":[0.000120323,0.00008937993,0.00012973111,0.00008193737,0.00009877468,0.00009299567,0.000098171746,0.00024442523,0.00030150873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008722974,0.000009280922,0.00028288914,0.000014234962,0.000002411278,0.000028964228,0.000008098902,0.000026483074,0.9988569,0.00005951644,0.00004306826,0.0005809261],"study_design_scores_gemma":[0.000021994154,0.000079763166,0.016980706,0.0000035780351,0.0000128519005,0.000250965,0.00003017147,0.0016013238,0.9775465,0.000029814331,0.0034383552,0.0000039062566],"about_ca_topic_score_codex":0.0018912911,"about_ca_topic_score_gemma":0.0028124296,"teacher_disagreement_score":0.0018912911,"about_ca_system_score_codex":0.0003259665,"about_ca_system_score_gemma":0.00023030683,"threshold_uncertainty_score":0.0037606359},"labels":[],"label_agreement":null},{"id":"W2003855355","doi":"10.1016/j.bmcl.2011.06.006","title":"Evaluation of FKBP and DHFR based destabilizing domains in Saccharomyces cerevisiae","year":2011,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health","keywords":"FKBP; Saccharomyces cerevisiae; Chemistry; Yeast; Mutant; In vivo; In vitro; Cell biology; Directed evolution; Biochemistry; Biology; Genetics; Gene","score_opus":0.04110595737420808,"score_gpt":0.2577830116315878,"score_spread":0.2166770542573797,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2003855355","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99600416,0.0009027933,0.0020795637,0.000058023088,0.000018277651,0.000026930951,0.00041791645,0.0000602006,0.00043213143],"genre_scores_gemma":[0.9954848,0.0005277994,0.002524959,0.000022962204,0.0000028142024,0.00001344944,0.0006461389,0.000021736778,0.00075519324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998273,0.00004107048,0.00003272801,0.00002443298,0.000053051925,0.00002137749],"domain_scores_gemma":[0.9998493,0.000041214407,0.000033633565,0.00001696879,0.00003103254,0.000027826783],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031202656,0.00041789084,0.00031576367,0.00018067184,0.00023575428,0.0003650267,0.00033316124,0.00027870853,0.0008037818],"category_scores_gemma":[0.00028967272,0.00013396972,0.0002688781,0.00022207329,0.00017717811,0.00017684106,0.00017794795,0.00037517937,0.000246601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034265287,0.00006646704,0.0003190293,0.000057309808,0.0000190817,0.00010324584,0.000025202791,0.0012789731,0.99536884,0.00016536428,0.00004256219,0.002211263],"study_design_scores_gemma":[0.00001821189,0.00026574533,0.0005626381,0.0000041807007,0.00002858683,0.000104051294,0.000032409527,0.0013365663,0.99607396,0.00001535389,0.0015515689,0.0000067228343],"about_ca_topic_score_codex":0.0036013967,"about_ca_topic_score_gemma":0.0033551925,"teacher_disagreement_score":0.0036013967,"about_ca_system_score_codex":0.00056261255,"about_ca_system_score_gemma":0.0003017169,"threshold_uncertainty_score":0.007160902},"labels":[],"label_agreement":null},{"id":"W2004516600","doi":"10.1038/bjc.2014.164","title":"Small molecule MIRA-1 induces in vitro and in vivo anti-myeloma activity and synergizes with current anti-myeloma agents","year":2014,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network; Toronto General Hospital","funders":"Ministry of Science and Technology of the People's Republic of China; Leukemia and Lymphoma Society","keywords":"Downregulation and upregulation; Apoptosis; Puma; Cancer research; Multiple myeloma; In vivo; Gene knockdown; Unfolded protein response; XBP1; Bortezomib; Endoplasmic reticulum; Dexamethasone; Doxorubicin; Biology; Medicine; Immunology; Chemotherapy; Internal medicine; Cell biology; RNA splicing; Biochemistry","score_opus":0.013532566386534968,"score_gpt":0.25949235392176534,"score_spread":0.24595978753523037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2004516600","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9797968,0.011302085,0.0026905008,0.0003743573,0.00023874053,0.00013503552,0.00080773584,0.00039750055,0.004257262],"genre_scores_gemma":[0.99027985,0.0035741013,0.0021306232,0.00014676181,0.00006688259,0.00012275526,0.0013847818,0.000032079413,0.0022620296],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978226,0.000050258677,0.00001794094,0.00003115265,0.000072255396,0.000046075467],"domain_scores_gemma":[0.99981767,0.000048445494,0.000044005417,0.00002456002,0.000018891149,0.00004652484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003055752,0.0004973977,0.0005083425,0.00050709466,0.00016444444,0.0003634731,0.00031705777,0.00043675408,0.002308614],"category_scores_gemma":[0.00024873283,0.00020443457,0.00043439295,0.00021763281,0.0002588945,0.0002370788,0.00017767718,0.0011303201,0.00078554277],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008920172,0.00082736724,0.00022804867,0.00015677964,0.000040692605,0.00005583709,0.000020135389,0.0002039528,0.98997843,0.00011256502,0.0003654115,0.0071187406],"study_design_scores_gemma":[0.00022915751,0.007491662,0.0042725913,0.000016219472,0.000072430434,0.00038931204,0.000019310351,0.0008069403,0.98006433,0.000062875086,0.006566475,0.0000087799235],"about_ca_topic_score_codex":0.00022325643,"about_ca_topic_score_gemma":0.0005291235,"teacher_disagreement_score":0.002308614,"about_ca_system_score_codex":0.00027849895,"about_ca_system_score_gemma":0.00026429805,"threshold_uncertainty_score":0.0077230334},"labels":[],"label_agreement":null},{"id":"W2006350698","doi":"10.1016/j.bpj.2008.12.2662","title":"Interaction between Cardiac Ryanodine Receptor and FK506-Binding Protein Revealed by Cryo-EM and FRET","year":2009,"lang":"en","type":"article","venue":"Biophysical Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Ryanodine receptor 2; Förster resonance energy transfer; Ryanodine receptor; Biophysics; FKBP; Green fluorescent protein; Yellow fluorescent protein; Fluorescence; Binding site; Calcium; Cell biology; Chemistry; Biochemistry; Biology; Receptor; Gene","score_opus":0.010128137153073147,"score_gpt":0.2557568595685991,"score_spread":0.24562872241552597,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2006350698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9762275,0.0010697017,0.01566849,0.00076737214,0.00006776861,0.000023311308,0.00018935112,0.00008931051,0.005897129],"genre_scores_gemma":[0.9890899,0.0006609214,0.0068636667,0.0002347029,0.000019585254,0.000045019868,0.00035362763,0.00008578736,0.0026467761],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999018,0.000016788108,0.0000047173007,0.000026176092,0.000022930895,0.000027603439],"domain_scores_gemma":[0.99981385,0.00008525507,0.0000221967,0.000034217403,0.000023112987,0.000021375796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00042937257,0.00029064092,0.0004174755,0.00012741804,0.0009254739,0.00060035754,0.0008225113,0.00067059905,0.0016070886],"category_scores_gemma":[0.00043295987,0.0003151165,0.00026859704,0.00016250537,0.00096703245,0.0010982434,0.0006248864,0.0023946338,0.00062774244],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023609457,0.00005495903,0.0004274959,0.000065390006,0.000018843279,0.00022749491,0.0001449937,0.00077876373,0.9943211,0.001603957,0.00034254446,0.0017782483],"study_design_scores_gemma":[0.000112003756,0.00016790025,0.0073802634,0.000035467157,0.000040109917,0.00075370335,0.00033555704,0.026799632,0.95804834,0.0010822976,0.005200739,0.00004392053],"about_ca_topic_score_codex":0.0013306685,"about_ca_topic_score_gemma":0.001517593,"teacher_disagreement_score":0.0016070886,"about_ca_system_score_codex":0.00080107193,"about_ca_system_score_gemma":0.00026762797,"threshold_uncertainty_score":0.0058122277},"labels":[],"label_agreement":null},{"id":"W2007491678","doi":"10.1111/j.1582-4934.2004.tb00262.x","title":"Differential gene expression in infarct scar and viable myocardium from rat heart following coronary ligation","year":2004,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Institute of Circulatory and Respiratory Health; Canadian Institutes of Health Research","keywords":"Ventricle; Internal medicine; Phospholamban; Endocrinology; Myocyte; Myocardial infarction; Heart failure; Ventricular remodeling; Medicine; Gene expression; Cardiology; Biology; Gene","score_opus":0.005842083075789587,"score_gpt":0.22779057317916343,"score_spread":0.22194849010337384,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2007491678","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99436873,0.003034429,0.0009919098,0.00004835021,0.000028168237,0.000017219932,0.0005051318,0.000037993683,0.00096811523],"genre_scores_gemma":[0.9828652,0.0042895284,0.0026053009,0.00014158507,0.00006400707,0.00022583042,0.0026746271,0.000038926835,0.007095006],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998549,0.00001016844,0.000010808796,0.00004080232,0.00003767247,0.000045557623],"domain_scores_gemma":[0.99980897,0.000025545465,0.000056640292,0.000016278338,0.00003101126,0.00006163339],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017817477,0.0002872832,0.00037411755,0.00054950954,0.00015538975,0.00030731736,0.0001349198,0.00026045647,0.0012467598],"category_scores_gemma":[0.00014604001,0.00024990403,0.00028044963,0.00029772078,0.00030911303,0.000239624,0.00020828209,0.00039121913,0.00037608107],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034473743,0.00002789826,0.0008775196,0.00006128087,0.000006120047,0.00009782667,0.00006374409,0.000011672192,0.9974607,0.000047963265,0.000022174721,0.000978431],"study_design_scores_gemma":[0.0001396405,0.003030306,0.25244817,0.000057975692,0.00016822749,0.001765233,0.000688137,0.0006807738,0.7370183,0.0002860519,0.0036892826,0.000027891472],"about_ca_topic_score_codex":0.00040454356,"about_ca_topic_score_gemma":0.0006942787,"teacher_disagreement_score":0.0012467598,"about_ca_system_score_codex":0.00016277877,"about_ca_system_score_gemma":0.00017340007,"threshold_uncertainty_score":0.0041707754},"labels":[],"label_agreement":null},{"id":"W2008421466","doi":"10.1083/jcb.151.1.117","title":"Glycogen Synthase Kinase-3β Is a Negative Regulator of Cardiomyocyte Hypertrophy","year":2000,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":395,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; American Heart Association; Medical Research Council; National Institutes of Health; Medical Research Council Canada","keywords":"Biology; GSK-3; Regulator; Glycogen synthase; Glycogen; Cell biology; Kinase; GSK3B; Biochemistry; ATP synthase; Glycogen debranching enzyme; Enzyme; Gene","score_opus":0.008216944926145102,"score_gpt":0.23002527087766175,"score_spread":0.22180832595151664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2008421466","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8383085,0.110699885,0.017289922,0.0026021309,0.001177241,0.00013651735,0.0018598019,0.0013306712,0.026595376],"genre_scores_gemma":[0.9688117,0.020917939,0.0021034644,0.0003750716,0.00012512066,0.000068110596,0.0011160757,0.000038469316,0.006444039],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992895,0.000010599852,0.000006134887,0.000016242455,0.000025206753,0.000012926317],"domain_scores_gemma":[0.999926,0.0000058813857,0.000025921474,0.000006172381,0.000011735618,0.00002436249],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015679881,0.00048466335,0.00021251378,0.0002294765,0.00017391454,0.00023424569,0.00014828955,0.00015986574,0.0009224579],"category_scores_gemma":[0.00015271241,0.00010014581,0.00016208306,0.00016937668,0.00029179372,0.00010422586,0.00022695008,0.00032493484,0.0005467852],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034880513,0.000033788572,0.0023899097,0.0002885792,0.00003293251,0.00076478824,0.000034618457,0.000145476,0.97634834,0.0010812797,0.0017844758,0.01674703],"study_design_scores_gemma":[0.0003153996,0.0010860687,0.111748315,0.00019272308,0.00017704249,0.010207221,0.000172439,0.0015464077,0.77959836,0.0052815443,0.089623176,0.00005123404],"about_ca_topic_score_codex":0.00029406985,"about_ca_topic_score_gemma":0.00033992942,"teacher_disagreement_score":0.0009224579,"about_ca_system_score_codex":0.00027386888,"about_ca_system_score_gemma":0.00031508374,"threshold_uncertainty_score":0.0030859709},"labels":[],"label_agreement":null},{"id":"W2009282630","doi":"10.1016/j.biochi.2005.04.010","title":"Molecular cloning, expression, purification and characterization of calcineurin from bovine cardiac muscle","year":2005,"lang":"en","type":"article","venue":"Biochimie","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan; Saskatchewan Cancer Agency","funders":"Saskatchewan Health Research Foundation; Heart and Stroke Foundation of Canada","keywords":"Amino acid; Calcineurin; Enzyme; Phosphatase; Biochemistry; Molecular cloning; Cloning (programming); Peptide sequence; Cardiac muscle; Calmodulin; Biology; Open reading frame; Amino acid residue; Chemistry; Molecular biology; Gene; Internal medicine","score_opus":0.007371234422708858,"score_gpt":0.2260976697476725,"score_spread":0.21872643532496366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2009282630","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9193786,0.020684734,0.043343622,0.0015664843,0.00042185345,0.0005297046,0.008438988,0.00031476325,0.0053212284],"genre_scores_gemma":[0.8126636,0.01528827,0.10131471,0.0005622436,0.0002412476,0.00042907486,0.04249898,0.00031753283,0.026684424],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997079,0.00003228461,0.00003555516,0.00007670816,0.00007695596,0.00007057717],"domain_scores_gemma":[0.9994849,0.0001408505,0.000100483965,0.000077783545,0.00009893195,0.00009710425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004797127,0.0005809665,0.00056440086,0.00055743096,0.0007409422,0.000695187,0.00091469905,0.0005451524,0.0011262703],"category_scores_gemma":[0.0007415257,0.0003792732,0.00062432536,0.0007763207,0.0004076765,0.000547394,0.0003678637,0.001110324,0.0008929244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012894571,0.000040394654,0.00022388727,0.00011590178,0.000011713693,0.00012608753,0.00007046364,0.00013916519,0.9964849,0.00037255324,0.00014216518,0.002143807],"study_design_scores_gemma":[0.00006503299,0.0002536339,0.01095523,0.00008536645,0.00007482996,0.0009399996,0.00010785333,0.0016096412,0.9540317,0.00039760262,0.03145309,0.000025987298],"about_ca_topic_score_codex":0.007455038,"about_ca_topic_score_gemma":0.008468695,"teacher_disagreement_score":0.007455038,"about_ca_system_score_codex":0.0011915512,"about_ca_system_score_gemma":0.00079086696,"threshold_uncertainty_score":0.0148233175},"labels":[],"label_agreement":null},{"id":"W2010678713","doi":"10.1016/j.yjmcc.2009.01.018","title":"The A-kinase anchor protein AKAP121 is a negative regulator of cardiomyocyte hypertrophy","year":2009,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Calcineurin; Muscle hypertrophy; Gene knockdown; Dephosphorylation; Cell biology; Phosphatase; Regulator; Immunoprecipitation; Biology; Effector; Myocyte; Intracellular; Phosphorylation; NFAT; Internal medicine; Kinase; Endocrinology; Medicine; Gene; Biochemistry","score_opus":0.005575470182847307,"score_gpt":0.21165015970632167,"score_spread":0.20607468952347435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2010678713","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845083,0.005934437,0.0046364204,0.0007115163,0.00027886027,0.000035048422,0.0005601638,0.00022379783,0.0031115108],"genre_scores_gemma":[0.9942629,0.0012643079,0.001077061,0.000096268945,0.00006217191,0.000032740623,0.00086006924,0.000036099722,0.0023082504],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997577,0.0000451355,0.000025450345,0.00005382435,0.00007735339,0.00004050364],"domain_scores_gemma":[0.9996393,0.00005939929,0.0001085069,0.000034732722,0.00003423375,0.00012380029],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020980285,0.0005943363,0.0004169116,0.0003930795,0.000480923,0.00056656403,0.00039320072,0.00053705927,0.0015393045],"category_scores_gemma":[0.00042612074,0.0003096233,0.00034878927,0.0002067595,0.00035845733,0.00030192695,0.00042888985,0.0010029887,0.0009058659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003588574,0.000023468323,0.00021763488,0.000033386306,0.000011405349,0.0002790479,0.000004626929,0.00006137877,0.99775934,0.00015979278,0.0001509282,0.0009400325],"study_design_scores_gemma":[0.00015319654,0.00041675832,0.018895376,0.000014761182,0.00006630194,0.0043994007,0.00006862725,0.002831926,0.96671385,0.00061383925,0.005796881,0.000029268229],"about_ca_topic_score_codex":0.00016443236,"about_ca_topic_score_gemma":0.00014072453,"teacher_disagreement_score":0.0015393045,"about_ca_system_score_codex":0.00037342345,"about_ca_system_score_gemma":0.00020107337,"threshold_uncertainty_score":0.005149424},"labels":[],"label_agreement":null},{"id":"W2011594548","doi":"10.1152/ajpheart.00546.2002","title":"Time-dependent systolic and diastolic function in mice overexpressing calcineurin","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Internal medicine; Diastole; Medicine; Sudden death; Ventricle; Cardiology; Calcineurin; Sudden cardiac death; Muscle hypertrophy; Left ventricular hypertrophy; Endocrinology; Blood pressure; Transplantation","score_opus":0.0077480284511564496,"score_gpt":0.23043528180071732,"score_spread":0.22268725334956085,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011594548","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957995,0.0009495248,0.0017219337,0.00005964033,0.000038101072,0.000022244854,0.00047754534,0.000089874295,0.000841681],"genre_scores_gemma":[0.99122065,0.0010470204,0.002403817,0.00007696808,0.000021571012,0.00009851645,0.001292961,0.00006994408,0.0037685456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997938,0.000025779384,0.00002571976,0.00006128261,0.00005418765,0.000039145274],"domain_scores_gemma":[0.9994048,0.0000646056,0.00021198759,0.00006432537,0.000049613496,0.00020483055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030154208,0.00039097868,0.000339361,0.0006373482,0.0001700137,0.0002842311,0.00020286081,0.00038149153,0.0013661758],"category_scores_gemma":[0.0002661676,0.00022922854,0.00026062937,0.00020629144,0.0003997289,0.00047218785,0.00022674893,0.0011913106,0.0002763702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048078288,0.000063529165,0.00070915686,0.000025194451,0.00000618383,0.000073076786,0.000035389363,0.000022306021,0.9970932,0.000048284,0.000026507987,0.0014163652],"study_design_scores_gemma":[0.00009007295,0.0024303757,0.072337955,0.00001908801,0.000066740206,0.0013079143,0.00007893725,0.00089190213,0.92109144,0.00015278267,0.0015101603,0.000022713773],"about_ca_topic_score_codex":0.00024160108,"about_ca_topic_score_gemma":0.00051700405,"teacher_disagreement_score":0.0013661758,"about_ca_system_score_codex":0.0001744994,"about_ca_system_score_gemma":0.00013181956,"threshold_uncertainty_score":0.0045703053},"labels":[],"label_agreement":null},{"id":"W2011648574","doi":"10.1074/jbc.m610834200","title":"The Role of Complex Formation between the Escherichia coli Hydrogenase Accessory Factors HypB and SlyD","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Peptidylprolyl isomerase; FKBP; Biology; Escherichia coli; Isomerase; Plasma protein binding; Biochemistry; Enzyme; Gene","score_opus":0.03252867645914363,"score_gpt":0.2736163661077889,"score_spread":0.24108768964864524,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2011648574","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971937,0.0005522243,0.0017888775,0.00007876737,0.000008160473,0.000008705282,0.000045960816,0.0000440765,0.00027953062],"genre_scores_gemma":[0.9968245,0.00014718248,0.002058551,0.000039861126,0.0000060955535,0.000009577843,0.00018452035,0.000028296681,0.0007013997],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980193,0.00003313387,0.000016412843,0.000041710224,0.000060369493,0.000046356872],"domain_scores_gemma":[0.99968183,0.000057320336,0.0000717599,0.000037019312,0.000035304707,0.00011678515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020708011,0.00047617508,0.00032604142,0.00018726189,0.00023230245,0.00069707783,0.00031949498,0.0004941014,0.0008565318],"category_scores_gemma":[0.00037243578,0.0003576538,0.00027373733,0.00011112265,0.0003219653,0.0005541436,0.00077842973,0.0005803555,0.00053345656],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013800642,0.00002528335,0.00079737126,0.00002815552,0.0000067196856,0.00011219243,0.000036355046,0.00004568959,0.99787176,0.00018387286,0.00003060523,0.00072403],"study_design_scores_gemma":[0.000047791316,0.00018484463,0.014998497,0.000011253594,0.000014486824,0.0009471624,0.00013203485,0.0041384697,0.9769851,0.00011763611,0.0024080744,0.000014718565],"about_ca_topic_score_codex":0.00077780423,"about_ca_topic_score_gemma":0.0005618658,"teacher_disagreement_score":0.0008565318,"about_ca_system_score_codex":0.00047491447,"about_ca_system_score_gemma":0.0002089293,"threshold_uncertainty_score":0.0034457445},"labels":[],"label_agreement":null},{"id":"W2012651936","doi":"10.1002/prot.21584","title":"Structural and enzymatic characterization of DR1281: A calcineurin‐like phosphoesterase from <i>Deinococcus radiodurans</i>","year":2007,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Basic Energy Sciences; National Institute of General Medical Sciences; U.S. Department of Energy","keywords":"Deinococcus radiodurans; Enzyme; Chemistry; Calcineurin; Biochemistry; DNA; Medicine","score_opus":0.005324051178692136,"score_gpt":0.20013508647618883,"score_spread":0.1948110352974967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012651936","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971692,0.0005508568,0.0007178463,0.0000789643,0.000008609059,0.000017370341,0.0007302266,0.000024907504,0.0007020411],"genre_scores_gemma":[0.98041564,0.0005749634,0.0068164254,0.000060504317,0.000012375228,0.00002354712,0.010113502,0.00002927023,0.0019538067],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991,0.000008249965,0.0000064314786,0.000022489787,0.000039012702,0.000013831645],"domain_scores_gemma":[0.9998267,0.000020657373,0.00006112866,0.000011874427,0.000031888,0.00004762812],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016009164,0.00041325446,0.0003018484,0.00016788406,0.00012309384,0.00024742718,0.000445033,0.00029809258,0.000642518],"category_scores_gemma":[0.00035479656,0.000111994836,0.000226432,0.00026675724,0.00015311003,0.00016269466,0.00019597345,0.00045141025,0.00041770304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001124603,0.000050784478,0.0020157492,0.00006907538,0.000006581448,0.00030165675,0.00004187197,0.00034860746,0.9933357,0.00007928312,0.00011254195,0.0035255665],"study_design_scores_gemma":[0.000088752764,0.0006043297,0.045191802,0.000025284118,0.00003155112,0.0045086974,0.0001528208,0.004051667,0.9263404,0.00015354493,0.0188162,0.000034841738],"about_ca_topic_score_codex":0.0016650003,"about_ca_topic_score_gemma":0.001173583,"teacher_disagreement_score":0.0016650003,"about_ca_system_score_codex":0.00048075896,"about_ca_system_score_gemma":0.0002956173,"threshold_uncertainty_score":0.0034881234},"labels":[],"label_agreement":null},{"id":"W2012695452","doi":"10.1016/s0735-1097(14)60788-9","title":"INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 IN HEART FAILURE PATIENTS: A NOVEL BIOMARKER OF MYOCARDIAL DIASTOLIC FUNCTION?","year":2014,"lang":"en","type":"article","venue":"Journal of the American College of Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Medicine; Biomarker; Internal medicine; Heart failure; Cardiology; Diastolic function; Diastole; Insulin-like growth factor; Insulin-like growth factor-binding protein; Diastolic heart failure; Growth factor; Blood pressure; Ejection fraction; Receptor; Biochemistry","score_opus":0.008504396416629386,"score_gpt":0.226704295421079,"score_spread":0.2181998990044496,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012695452","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97593415,0.014619053,0.0009706956,0.0029137828,0.0005595812,0.000027909373,0.0007800375,0.000044804572,0.004149953],"genre_scores_gemma":[0.9932059,0.002786798,0.0011344269,0.00077992154,0.00078480336,0.00003441224,0.0005655795,0.000006544358,0.0007017363],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99968565,0.00009384129,0.00004083589,0.00006191875,0.000071139155,0.000046551624],"domain_scores_gemma":[0.9988986,0.00032155996,0.00028989,0.000052330124,0.00016910309,0.00026852917],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008723617,0.00070095557,0.0012916519,0.00066705473,0.00029199995,0.0015724435,0.0005481168,0.0013421968,0.0012617896],"category_scores_gemma":[0.0019064078,0.0002618346,0.00043048037,0.0008411554,0.00037374377,0.00066171825,0.00033799972,0.0014541288,0.00039156235],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018815335,0.00028128808,0.9687288,0.00009911463,0.00042831016,0.00030154703,0.000047422705,0.00014451671,0.0043512415,0.00018113307,0.0013060368,0.022249142],"study_design_scores_gemma":[0.00020425371,0.0010260531,0.9893083,0.000079279336,0.00067466206,0.0010454863,0.0002913223,0.002627613,0.0015300895,0.0007497804,0.0024203588,0.000042824402],"about_ca_topic_score_codex":0.0004338783,"about_ca_topic_score_gemma":0.0008309837,"teacher_disagreement_score":0.0015724435,"about_ca_system_score_codex":0.00027788442,"about_ca_system_score_gemma":0.00033111888,"threshold_uncertainty_score":0.0046135187},"labels":[],"label_agreement":null},{"id":"W2012738107","doi":"10.1016/s0378-1119(01)00771-5","title":"Gene structure and expression of the mouse adipocyte enhancer-binding protein","year":2001,"lang":"en","type":"article","venue":"Gene","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Diabetes Association; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Biology; Gene isoform; Alternative splicing; Molecular biology; Exon; Gene expression; Gene; Precursor mRNA; Regulation of gene expression; RNA splicing; Genetics; RNA","score_opus":0.008613074989115658,"score_gpt":0.22796947641027665,"score_spread":0.219356401421161,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2012738107","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9872476,0.0024878914,0.0064171273,0.00023726895,0.000026820879,0.000015090558,0.000655334,0.00007336964,0.0028395494],"genre_scores_gemma":[0.98687845,0.0006848457,0.0034682818,0.00009352972,0.000015501531,0.000026252368,0.0016537878,0.00006057432,0.007118845],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989474,0.00001230381,0.0000045267675,0.000031437194,0.000028285906,0.000028754179],"domain_scores_gemma":[0.9998468,0.00003959751,0.000030210049,0.000017559027,0.000021808095,0.00004399218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001102297,0.00019949237,0.00017248634,0.0005094085,0.0003194645,0.00032457508,0.00025879356,0.00032408928,0.001156261],"category_scores_gemma":[0.00015308156,0.00028860642,0.00020350458,0.00023906882,0.0003891547,0.00021968363,0.00022864791,0.00073788234,0.00063680456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013961435,0.000014021633,0.00025800912,0.000009688117,0.0000023122072,0.0000458946,0.000019792878,0.000060802733,0.99756587,0.0010594263,0.00002849014,0.00079613004],"study_design_scores_gemma":[0.00004849147,0.00019819768,0.030368816,0.000014512758,0.000030300018,0.0006121108,0.00008981521,0.0014849319,0.9611272,0.0012104962,0.0048028957,0.0000122363035],"about_ca_topic_score_codex":0.0012467572,"about_ca_topic_score_gemma":0.0021477828,"teacher_disagreement_score":0.0012467572,"about_ca_system_score_codex":0.0004710035,"about_ca_system_score_gemma":0.00027033762,"threshold_uncertainty_score":0.003868103},"labels":[],"label_agreement":null},{"id":"W2013865636","doi":"10.1016/s1567-5769(01)00002-9","title":"Selective pharmacological inhibitors reveal differences between Thy-1- and T cell receptor-mediated signal transduction in mouse T lymphocytes","year":2001,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Killam Trusts; Dalhousie University","keywords":"Signal transduction; Biology; Cell biology; T cell; T-cell receptor; MAPK/ERK pathway; CD3; Kinase; Mitogen-activated protein kinase; Wortmannin; Molecular biology; Protein kinase B; Immunology; CD8; Immune system","score_opus":0.014681496967662093,"score_gpt":0.2756319429044274,"score_spread":0.2609504459367653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013865636","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876802,0.0032399963,0.004583265,0.00023998781,0.000042297957,0.00003793984,0.0005838065,0.00015003825,0.0034424486],"genre_scores_gemma":[0.98924506,0.0029298353,0.0030255062,0.00010522717,0.000025008734,0.00007701778,0.00072483043,0.00007052131,0.0037970685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997652,0.000027836279,0.000021552796,0.00004008531,0.000049211023,0.00009612509],"domain_scores_gemma":[0.99982774,0.00005132721,0.00004763344,0.000021370404,0.000012135624,0.00003975545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022638665,0.00048557058,0.00027599258,0.0004826415,0.00023191783,0.0005504345,0.00044435813,0.00033971012,0.0016650264],"category_scores_gemma":[0.00020724445,0.00030753657,0.00035745744,0.00028470624,0.00038392973,0.00034399403,0.00018972936,0.0009899314,0.0005763285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016627621,0.000018543638,0.000056750192,0.000020951626,0.0000037863363,0.00002237874,0.000008177987,0.000030854484,0.9987326,0.00022034257,0.000020937523,0.0006983492],"study_design_scores_gemma":[0.000025196796,0.000120074845,0.0009388783,0.0000037652994,0.000016637,0.00012319825,0.000011761519,0.00026547577,0.9977443,0.000056203342,0.0006920283,0.0000024130754],"about_ca_topic_score_codex":0.0005155263,"about_ca_topic_score_gemma":0.0008710693,"teacher_disagreement_score":0.0016650264,"about_ca_system_score_codex":0.00051154743,"about_ca_system_score_gemma":0.00027960038,"threshold_uncertainty_score":0.005570054},"labels":[],"label_agreement":null},{"id":"W2014861937","doi":"10.1016/s0166-6851(01)00321-8","title":"A Schistosoma mansoni Pad1 homologue stabilizes c-Jun","year":2001,"lang":"en","type":"article","venue":"Molecular and Biochemical Parasitology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Transactivation; Proteasome; Biology; Molecular biology; Cytoplasm; Transcription (linguistics); Reporter gene; Cell biology; Transcription factor; Gene; Gene expression; Biochemistry","score_opus":0.007631524600782805,"score_gpt":0.26677439920025503,"score_spread":0.2591428745994722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2014861937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946595,0.0012318434,0.002630545,0.00012998958,0.00004981867,0.000010595815,0.00021979833,0.00009427435,0.00097364286],"genre_scores_gemma":[0.9964774,0.0002991181,0.0008178351,0.000039227005,0.000008881649,0.000009808183,0.00051870756,0.000017829443,0.0018111928],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999274,0.000010504696,0.000005477328,0.000020109428,0.0000147046585,0.000021808897],"domain_scores_gemma":[0.9998355,0.00003045004,0.000047843732,0.000027015267,0.000014713868,0.000044553304],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001517234,0.00034271154,0.00016289274,0.00017430933,0.000353185,0.0002925221,0.00023366013,0.00025954895,0.0019475715],"category_scores_gemma":[0.00020909353,0.00017415649,0.00022524467,0.00010324074,0.00025354285,0.00024277873,0.00030655533,0.0006021905,0.0009546921],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019877712,0.000017004862,0.00018706394,0.000042084223,0.000004263433,0.0001065348,0.000011360233,0.000059995073,0.9981008,0.00020626505,0.00007037143,0.0009954859],"study_design_scores_gemma":[0.000020144118,0.00008866735,0.0044561666,0.000004605275,0.000008626265,0.0005099342,0.0000330158,0.0009242086,0.9918046,0.000111149726,0.0020345927,0.0000042583224],"about_ca_topic_score_codex":0.00017965623,"about_ca_topic_score_gemma":0.0002948517,"teacher_disagreement_score":0.0019475715,"about_ca_system_score_codex":0.00031312587,"about_ca_system_score_gemma":0.0001403141,"threshold_uncertainty_score":0.006515324},"labels":[],"label_agreement":null},{"id":"W2015384362","doi":"10.1002/pmic.201200455","title":"Pilot study identifying myosin heavy chain 7, desmin, insulin‐like growth factor 7, and annexin <scp>A</scp> 2 as circulating biomarkers of human heart failure","year":2013,"lang":"en","type":"article","venue":"PROTEOMICS","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Ottawa; Heart and Stroke Foundation; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Desmin; Myosin; Insulin-like growth factor; Annexin; Growth factor; Annexin A2; Heart failure; Annexin A5; Chemistry; Medicine; Internal medicine; Biochemistry; Immunohistochemistry; Apoptosis","score_opus":0.02486470376439802,"score_gpt":0.266577517777265,"score_spread":0.24171281401286698,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015384362","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99821967,0.00032177963,0.00096130255,0.000039817194,0.000007692304,0.000048794765,0.00025791244,0.000020273561,0.00012272374],"genre_scores_gemma":[0.9944636,0.0002324044,0.003898481,0.000106400956,0.000034764926,0.00003963632,0.0009432161,0.00000966912,0.00027184852],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99970263,0.00008358006,0.000016139194,0.00010741169,0.000058076534,0.000032184285],"domain_scores_gemma":[0.99944085,0.00016323412,0.00008146344,0.000054222997,0.00011597871,0.00014427412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011990572,0.00049789785,0.00046418517,0.0005948449,0.0003390021,0.00042821333,0.00022083995,0.000369039,0.00051451556],"category_scores_gemma":[0.00075634086,0.00015718966,0.00028438045,0.00033044934,0.00020975145,0.00019216446,0.0003020211,0.00029858947,0.00014261356],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0066856677,0.0016012086,0.16220489,0.00021970338,0.00037437692,0.0010824389,0.00021153224,0.00063491095,0.80874336,0.00010876251,0.00051253993,0.01762071],"study_design_scores_gemma":[0.0004760251,0.012512138,0.82452244,0.000026211197,0.00058183394,0.0023044439,0.00024024403,0.006610902,0.15023735,0.00020836644,0.0022400809,0.000040049912],"about_ca_topic_score_codex":0.0008273196,"about_ca_topic_score_gemma":0.0008792979,"teacher_disagreement_score":0.0011990572,"about_ca_system_score_codex":0.00019547294,"about_ca_system_score_gemma":0.00031968296,"threshold_uncertainty_score":0.0063412786},"labels":[],"label_agreement":null},{"id":"W2015922146","doi":"10.1074/jbc.m207910200","title":"Regulation of GTP-binding Protein αq(Gαq) Signaling by the Ezrin-Radixin-Moesin-binding Phosphoprotein-50 (EBP50)","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Radixin; Ezrin; Phosphoprotein; Moesin; Cell biology; GTP'; Chemistry; Phosphorylation; Biology; Biochemistry; Cytoskeleton; Cell; Enzyme","score_opus":0.024119219668000652,"score_gpt":0.23586264110005759,"score_spread":0.21174342143205693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015922146","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964875,0.0013386153,0.0011977758,0.00009262639,0.000011115925,0.000015923146,0.00010233797,0.000043383192,0.00071057666],"genre_scores_gemma":[0.99750584,0.00094869325,0.0006843071,0.000054021595,0.000004058011,0.000017038705,0.00012892835,0.0000075534126,0.0006496575],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992585,0.000015766402,0.0000054781553,0.000012778094,0.00001165491,0.00002840026],"domain_scores_gemma":[0.9999713,0.0000051243283,0.00001088219,0.0000029451248,0.0000019023333,0.000007927342],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008867267,0.0003171007,0.0001478004,0.0001713425,0.000111812056,0.00023447695,0.00012949394,0.00025134563,0.00063863484],"category_scores_gemma":[0.00007827978,0.00010166997,0.00026534538,0.00010179937,0.00024400889,0.00013540841,0.0002448983,0.0002802246,0.00031095272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000083389765,0.0000123891805,0.00015723193,0.000019380837,0.0000044683175,0.00008896032,0.000008200173,0.000089898465,0.9984849,0.000105865896,0.000029186009,0.00091601163],"study_design_scores_gemma":[0.00006524381,0.00024522972,0.01825623,0.000008457533,0.000022226304,0.00048469615,0.000041757987,0.0033321134,0.9749972,0.00016082865,0.002379708,0.0000063943603],"about_ca_topic_score_codex":0.0005740933,"about_ca_topic_score_gemma":0.0007284707,"teacher_disagreement_score":0.00063863484,"about_ca_system_score_codex":0.0003543661,"about_ca_system_score_gemma":0.000101987775,"threshold_uncertainty_score":0.002571106},"labels":[],"label_agreement":null},{"id":"W2015988724","doi":"10.1073/pnas.0406874102","title":"Convergent signaling by acidosis and receptor activator of NF-κB ligand (RANKL) on the calcium/calcineurin/NFAT pathway in osteoclasts","year":2005,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":159,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; Western University","funders":"","keywords":"NFAT; RANKL; Calcineurin; Endocrinology; Internal medicine; Osteoclast; Acidosis; Chemistry; Extracellular; Cell biology; Biology; Activator (genetics); Receptor; Medicine; Transplantation","score_opus":0.030596987484451332,"score_gpt":0.28199432545488023,"score_spread":0.2513973379704289,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2015988724","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96417755,0.025946537,0.006047782,0.00032211142,0.00008902941,0.00009034514,0.0005579025,0.00010127704,0.0026674422],"genre_scores_gemma":[0.9881555,0.006590646,0.0026597995,0.00011251816,0.000043759395,0.00008168637,0.0003505213,0.000008283457,0.0019973395],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99971515,0.00004557341,0.000025903382,0.000048306465,0.00009621585,0.0000689649],"domain_scores_gemma":[0.9998994,0.000009412189,0.000029840701,0.0000089469095,0.000021862717,0.00003063629],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029528607,0.00040690947,0.00039902722,0.00030997625,0.00027734076,0.00040249538,0.00017324275,0.0002815674,0.0007266412],"category_scores_gemma":[0.00012850019,0.00015863108,0.00053869834,0.0002146234,0.00035355287,0.0003128937,0.00056301197,0.0005670608,0.00019178921],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052034523,0.000025946523,0.00080305064,0.00020776971,0.000017187098,0.00037931092,0.00007693208,0.00009153999,0.99515766,0.0002510789,0.00004903784,0.0024201153],"study_design_scores_gemma":[0.00041117615,0.0019694658,0.09864608,0.0001099831,0.00024975464,0.0036236234,0.0006005002,0.0030013719,0.8773989,0.0013823727,0.012549173,0.000057614023],"about_ca_topic_score_codex":0.00059162884,"about_ca_topic_score_gemma":0.0009467788,"teacher_disagreement_score":0.0007266412,"about_ca_system_score_codex":0.00031206018,"about_ca_system_score_gemma":0.00034811356,"threshold_uncertainty_score":0.0024308562},"labels":[],"label_agreement":null},{"id":"W2016005076","doi":"10.1016/j.molcel.2014.05.012","title":"The Calcineurin Signaling Network Evolves via Conserved Kinase-Phosphatase Modules that Transcend Substrate Identity","year":2014,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":118,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Calcineurin; Biology; Phosphatase; Kinase; Dephosphorylation; Cell biology; Phosphorylation; Biochemistry; Computational biology","score_opus":0.011054816560845131,"score_gpt":0.22372086381445785,"score_spread":0.2126660472536127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016005076","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9651447,0.0012876868,0.026444677,0.0003378833,0.00005258019,0.000020915875,0.000071548144,0.0002581472,0.0063819634],"genre_scores_gemma":[0.99335927,0.0004963772,0.0047746985,0.00006649385,0.000013129865,0.000007191951,0.00008792108,0.000027243148,0.0011677014],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998233,0.00002277758,0.000009722409,0.000053279313,0.00005431259,0.000036555946],"domain_scores_gemma":[0.9997776,0.000027066748,0.00005364084,0.00004748827,0.000043602875,0.00005063563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003101273,0.00025338627,0.00026143098,0.0002832991,0.00037984343,0.0013052132,0.00057378336,0.0004465926,0.00068035687],"category_scores_gemma":[0.000536224,0.00024030147,0.00021734934,0.00023715157,0.00061217527,0.0011168624,0.00065205107,0.00087299955,0.00050628255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015404531,0.000030265499,0.0027199858,0.000038064543,0.000024010096,0.00038973705,0.0001234183,0.0013724312,0.9578357,0.021886107,0.00016366027,0.015262637],"study_design_scores_gemma":[0.00007245723,0.00030915882,0.035216283,0.000042270498,0.00010385099,0.0033849666,0.00024459427,0.033249866,0.88923913,0.020922573,0.017150015,0.00006480225],"about_ca_topic_score_codex":0.00044532752,"about_ca_topic_score_gemma":0.00053391187,"teacher_disagreement_score":0.0013052132,"about_ca_system_score_codex":0.0005635749,"about_ca_system_score_gemma":0.00042226026,"threshold_uncertainty_score":0.0040890574},"labels":[],"label_agreement":null},{"id":"W2016384179","doi":"10.1002/pro.89","title":"Characterizing and controlling the inherent dynamics of cyclophilin‐A","year":2009,"lang":"en","type":"article","venue":"Protein Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"High Magnetic Field Laboratory, Chinese Academy of Sciences; Division of Materials Research; University of Toronto; National High Magnetic Field Laboratory; National Science Foundation","keywords":"Cypa; Cyclophilin A; Protein dynamics; Cyclophilin; Chemistry; Molecular dynamics; Relaxation (psychology); Active site; Chemical physics; Biophysics; Dynamics (music); Enzyme; Biological system; Computational chemistry; Physics; Biochemistry; Biology","score_opus":0.009894098648683501,"score_gpt":0.25134854939722506,"score_spread":0.24145445074854155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016384179","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934256,0.00026980985,0.0059470306,0.000032049225,0.000004107229,0.0000064908904,0.00004685329,0.000025907093,0.00024211446],"genre_scores_gemma":[0.9951597,0.00030851178,0.0042954665,0.000013944179,0.0000042754905,0.00000944207,0.000056252633,0.00000813014,0.0001443988],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999306,0.000013096546,0.0000036296867,0.000022188013,0.000022087137,0.000008473469],"domain_scores_gemma":[0.9998621,0.00005579353,0.000037184942,0.0000151382865,0.000010511526,0.0000192903],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018387378,0.00012485989,0.00013423493,0.00010620928,0.00012262944,0.00021972113,0.00014990142,0.00013758863,0.00031205692],"category_scores_gemma":[0.00029405413,0.000100008096,0.00007074578,0.00009349735,0.0002395137,0.00021817465,0.0001292895,0.0002885195,0.00007134747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000016591563,0.0000063418097,0.00037561014,0.000009308062,0.0000021833491,0.000005801164,0.000007721667,0.00034679158,0.99793494,0.00013498824,0.000008640684,0.0011511628],"study_design_scores_gemma":[0.000008341959,0.00007745487,0.0057633836,0.000002717484,0.0000066129296,0.00008770067,0.000017315644,0.013810991,0.9791252,0.0002057697,0.0008868574,0.000007713335],"about_ca_topic_score_codex":0.0004194737,"about_ca_topic_score_gemma":0.00080554537,"teacher_disagreement_score":0.0004194737,"about_ca_system_score_codex":0.00016800784,"about_ca_system_score_gemma":0.00011045793,"threshold_uncertainty_score":0.0012190342},"labels":[],"label_agreement":null},{"id":"W2016391040","doi":"10.1139/o04-123","title":"Cardiac-specific transgenic overexpression of α<sub>1B</sub>-adrenergic receptors induce chronic activation of ERK MAPK signalling","year":2004,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"MAPK/ERK pathway; Calcineurin; Kinase; Phosphatase; Receptor; Phosphorylation; Biology; Alpha (finance); Adrenergic receptor; Endocrinology; Protein kinase A; Internal medicine; Cell biology; Transgene; Signal transduction; Mitogen-activated protein kinase; Extracellular; Molecular biology; Medicine; Biochemistry; Gene","score_opus":0.009729004826649386,"score_gpt":0.21648502712196677,"score_spread":0.2067560222953174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016391040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956468,0.001013548,0.001265539,0.00009111072,0.000056985573,0.000036070145,0.0006466623,0.00006662365,0.0011766369],"genre_scores_gemma":[0.9865155,0.00144727,0.0024774657,0.00013840107,0.000039607217,0.00011920819,0.0017361726,0.000065458255,0.0074607865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997427,0.00002749853,0.000036249316,0.00005417584,0.000058697387,0.000080632744],"domain_scores_gemma":[0.999778,0.000025922605,0.000083808496,0.000024732268,0.000018509414,0.000069122136],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022687913,0.0003436748,0.00029535615,0.00028348548,0.0001772229,0.0004165844,0.00019476745,0.00031395658,0.0018740783],"category_scores_gemma":[0.00009120775,0.0002769199,0.0003265827,0.00015735897,0.00026756214,0.00021878377,0.0002192509,0.0011260975,0.00081983407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008793166,0.000026871608,0.00009904777,0.0000111110085,0.0000025327613,0.000024375766,0.000007173334,0.000009271942,0.99947613,0.000025720541,0.000019146302,0.00021081723],"study_design_scores_gemma":[0.00004904901,0.0009337478,0.015156512,0.000013001145,0.000032795375,0.00044473223,0.000078919235,0.0004984946,0.9800168,0.000050184455,0.0027173662,0.000008285155],"about_ca_topic_score_codex":0.00033075918,"about_ca_topic_score_gemma":0.00074810244,"teacher_disagreement_score":0.0018740783,"about_ca_system_score_codex":0.00024735052,"about_ca_system_score_gemma":0.00012705976,"threshold_uncertainty_score":0.006269455},"labels":[],"label_agreement":null},{"id":"W2016728727","doi":"10.1186/1742-2094-9-64","title":"A novel anti-EMMPRIN function-blocking antibody reduces T cell proliferation and neurotoxicity: relevance to multiple sclerosis","year":2012,"lang":"en","type":"article","venue":"Journal of Neuroinflammation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Basigin; clone (Java method); Monoclonal antibody; Experimental autoimmune encephalomyelitis; T cell; Immunology; Multiple sclerosis; Blocking antibody; Matrix metalloproteinase; Antibody; Biology; Chemistry; Molecular biology; Immune system; Biochemistry","score_opus":0.029127434209838196,"score_gpt":0.25568330521561816,"score_spread":0.22655587100577995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2016728727","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9905826,0.0024550585,0.0048678913,0.00012404667,0.000052407424,0.00008318525,0.00014890071,0.00012973808,0.0015561392],"genre_scores_gemma":[0.98585594,0.0022709046,0.007700578,0.00018555515,0.000050021903,0.00013413148,0.00076808553,0.000022549239,0.0030120742],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998778,0.000013096241,0.000011773816,0.00002798294,0.000032145133,0.000037072292],"domain_scores_gemma":[0.9999013,0.000014960209,0.00002760656,0.000007751624,0.000019550385,0.000028836228],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015787582,0.0005480659,0.00028218766,0.00025662864,0.00012252424,0.00019948134,0.00041274363,0.0005284499,0.0010506226],"category_scores_gemma":[0.00014169696,0.00012381015,0.00028202494,0.00012344353,0.0001624863,0.00014473604,0.0001192757,0.0007223468,0.00034981358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001008521,0.0001404053,0.00011601033,0.000044266657,0.000007967857,0.00005900929,0.0000043990394,0.000050219995,0.99707675,0.000032165295,0.000050331328,0.0023177208],"study_design_scores_gemma":[0.0001349916,0.002032091,0.0033679355,0.000013283584,0.00008290744,0.00080957083,0.0000058026476,0.0005510718,0.9898074,0.0000200919,0.0031706018,0.0000042628744],"about_ca_topic_score_codex":0.0004826834,"about_ca_topic_score_gemma":0.0008917434,"teacher_disagreement_score":0.0010506226,"about_ca_system_score_codex":0.00040800966,"about_ca_system_score_gemma":0.00033073366,"threshold_uncertainty_score":0.003514707},"labels":[],"label_agreement":null},{"id":"W2017068027","doi":"10.1016/j.yjmcc.2007.07.055","title":"Matrix metalloproteinase-2 degrades the cytoskeletal protein α-actinin in peroxynitrite mediated myocardial injury","year":2007,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":152,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Peroxynitrite; Desmin; Spectrin; Sarcomere; Cytoskeleton; Chemistry; Cell biology; Matrix metalloproteinase; Myocyte; Biochemistry; Internal medicine; Biology; Medicine; Vimentin; Enzyme; Superoxide","score_opus":0.007224660516874907,"score_gpt":0.24571167757139437,"score_spread":0.23848701705451947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017068027","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925569,0.0032435136,0.002805408,0.0002640097,0.000101917394,0.000015909118,0.000050653663,0.00004257334,0.00091908313],"genre_scores_gemma":[0.994909,0.00083807524,0.0009488576,0.000047842434,0.00005283996,0.000015950589,0.00014254604,0.000009029537,0.0030359216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99968994,0.00006799209,0.000024715613,0.000040642273,0.0000685402,0.00010831172],"domain_scores_gemma":[0.99980074,0.000026167558,0.000047815025,0.000022866889,0.00003588735,0.000066628265],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005250523,0.0004166339,0.00034776496,0.0004492934,0.00034882448,0.00045939282,0.00021044418,0.0005259146,0.0015467007],"category_scores_gemma":[0.00034794185,0.00037241165,0.0004023569,0.0001470158,0.00033385277,0.00047867792,0.00021782484,0.0007757018,0.00035144444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091108854,0.00009212266,0.0005009279,0.000039375183,0.000017775024,0.00041925305,0.00003845173,0.000028621125,0.9962224,0.00027235266,0.000114345065,0.001343169],"study_design_scores_gemma":[0.00011851188,0.000687875,0.015932044,0.000007937788,0.000055115455,0.00309124,0.00011872263,0.0012062882,0.9766558,0.0002931296,0.0018261953,0.0000072422235],"about_ca_topic_score_codex":0.00034671125,"about_ca_topic_score_gemma":0.0005971993,"teacher_disagreement_score":0.0015467007,"about_ca_system_score_codex":0.00044188014,"about_ca_system_score_gemma":0.0002566345,"threshold_uncertainty_score":0.005174279},"labels":[],"label_agreement":null},{"id":"W2017372504","doi":"10.1016/s1534-5807(02)00369-6","title":"Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts","year":2002,"lang":"en","type":"article","venue":"Developmental Cell","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2679,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Precursory Research for Embryonic Science and Technology; Japan Orthopaedics and Traumatology Foundation; CYTED Ciencia y Tecnología para el Desarrollo; Ministry of Health, Labour and Welfare; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Japan Science and Technology Corporation; McGill University","keywords":"RANKL; Cell biology; NFAT; Biology; Transcription factor; Osteoclast; Cellular differentiation; Signal transduction; Ectopic expression; Embryonic stem cell; Calcineurin; Activator (genetics); Receptor; Cell culture; Internal medicine; Genetics; Transplantation; Gene","score_opus":0.017677317655058748,"score_gpt":0.20627664714599758,"score_spread":0.18859932949093883,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2017372504","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97157574,0.00763215,0.01094005,0.00058526907,0.00010200647,0.00003939659,0.0012873133,0.00032269713,0.007515333],"genre_scores_gemma":[0.978864,0.0013852578,0.00441715,0.00011117205,0.000037697628,0.000028391256,0.0012052782,0.000077128345,0.013873931],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993573,0.00005547194,0.000030250194,0.00007271898,0.00023901582,0.00024532012],"domain_scores_gemma":[0.9997713,0.00001839161,0.000036099802,0.00002880626,0.00006005246,0.00008536527],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027802514,0.00042510702,0.0003675195,0.00051853945,0.0005467711,0.0009502853,0.0003343774,0.000419355,0.0019057357],"category_scores_gemma":[0.00025257774,0.00036247447,0.0005012684,0.00034015716,0.0004414789,0.0005271929,0.00060297304,0.0012612783,0.0011064879],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022791112,0.000020836607,0.00037412532,0.00002235205,0.0000029697756,0.00007510037,0.000022114133,0.00007480244,0.99682933,0.00050683715,0.000093384355,0.0017502933],"study_design_scores_gemma":[0.000025650235,0.000074936994,0.008254441,0.000005869155,0.000014155507,0.00034431228,0.0000549755,0.00059169624,0.9849636,0.0002885495,0.0053730994,0.000008770874],"about_ca_topic_score_codex":0.002133709,"about_ca_topic_score_gemma":0.006701727,"teacher_disagreement_score":0.002133709,"about_ca_system_score_codex":0.0013505445,"about_ca_system_score_gemma":0.000720981,"threshold_uncertainty_score":0.009799004},"labels":[],"label_agreement":null},{"id":"W2018026238","doi":"10.1523/jneurosci.5154-06.2007","title":"Pancortin-2 Interacts with WAVE1 and Bcl-xL in a Mitochondria-Associated Protein Complex That Mediates Ischemic Neuronal Death","year":2007,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"National Institute on Aging; National Institutes of Health","keywords":"Mitochondrion; Cell biology; Biology; Apoptosis; Ischemia; Programmed cell death; Cerebral cortex; Actin; Cortex (anatomy); Mediator; Neuroscience; Internal medicine; Medicine; Biochemistry","score_opus":0.031030526799818412,"score_gpt":0.27617334147334915,"score_spread":0.24514281467353075,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018026238","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940866,0.0014124687,0.003416366,0.00013017803,0.000018356912,0.000012191335,0.00011051068,0.00004324022,0.0007700684],"genre_scores_gemma":[0.99398583,0.00062230305,0.002207144,0.000063443855,0.000010084034,0.00001750299,0.0005578443,0.000019153957,0.0025166166],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983525,0.000027315362,0.0000118737935,0.00004072493,0.00004857032,0.000036185735],"domain_scores_gemma":[0.9998368,0.000012474695,0.000066198765,0.000018210912,0.00001814566,0.000048190446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015046049,0.00046877068,0.00017370672,0.000253097,0.00035509805,0.00040300682,0.00022599609,0.00029099945,0.0010528704],"category_scores_gemma":[0.0001797018,0.00021155631,0.00020331683,0.00014016595,0.00016307813,0.0004466514,0.00044424844,0.00037218077,0.0005180074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009918255,0.000011888594,0.0006971882,0.000020487041,0.0000085002275,0.00012675991,0.000015163702,0.000033726858,0.9982424,0.00010918356,0.000040078874,0.00059556257],"study_design_scores_gemma":[0.00006593003,0.0001820197,0.032175183,0.000015796442,0.000037805406,0.002366533,0.000070897724,0.0027422959,0.95835656,0.00028177226,0.0036957217,0.000009481667],"about_ca_topic_score_codex":0.0002761845,"about_ca_topic_score_gemma":0.00056670984,"teacher_disagreement_score":0.0010528704,"about_ca_system_score_codex":0.0005186818,"about_ca_system_score_gemma":0.00013056931,"threshold_uncertainty_score":0.003763318},"labels":[],"label_agreement":null},{"id":"W2018468066","doi":"10.1002/1521-4141(200205)32:5<1223::aid-immu1223>3.0.co;2-5","title":"Calcineurin Aα plays an exclusive role in TCR signaling in mature but not in immature T cells","year":2002,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; Calcineurin; T-cell receptor; T cell; Lymphocytic choriomeningitis; Thymocyte; Cell biology; NFAT; Immunology; Molecular biology; Antigen; Transcription factor; CD8; Immune system; Transplantation; Internal medicine; Biochemistry; Gene","score_opus":0.01131442814144367,"score_gpt":0.2194964613494321,"score_spread":0.20818203320798842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018468066","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99195814,0.004150655,0.0023624497,0.000047612368,0.000015322505,0.000012452213,0.0001695142,0.000054964803,0.0012288968],"genre_scores_gemma":[0.9953265,0.0014084321,0.0012801944,0.00001894555,0.00002544321,0.000011289452,0.00029289664,0.000010328581,0.0016260425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988675,0.000009126528,0.000010351718,0.00003737315,0.000032384694,0.000023893532],"domain_scores_gemma":[0.99971443,0.000032331405,0.00006954853,0.000041771935,0.000040528354,0.00010126896],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001320134,0.00025171327,0.00021298621,0.00025569275,0.000198378,0.0005087999,0.00021919908,0.0002494824,0.0007403842],"category_scores_gemma":[0.0002065471,0.00012027402,0.00015914632,0.0001624135,0.00030281744,0.0003907003,0.0001808366,0.00043898175,0.0002606244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000064513595,0.0000064999094,0.00044588718,0.000011352228,0.0000010801882,0.00006872279,0.000008301167,0.000010093203,0.99869484,0.00007269665,0.00000472929,0.0006112972],"study_design_scores_gemma":[0.000035856272,0.0003278293,0.028485185,0.000013120076,0.000027191263,0.0026671202,0.000066847744,0.0005903049,0.964577,0.0003264639,0.0028767453,0.000006342712],"about_ca_topic_score_codex":0.0003895851,"about_ca_topic_score_gemma":0.0004491465,"teacher_disagreement_score":0.0007403842,"about_ca_system_score_codex":0.0002570807,"about_ca_system_score_gemma":0.00028037344,"threshold_uncertainty_score":0.0024768114},"labels":[],"label_agreement":null},{"id":"W2018631267","doi":"10.1074/jbc.m115.644302","title":"Apolipoprotein D Internalization Is a Basigin-dependent Mechanism","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Internalization; Basigin; Lipocalin; Biology; Neuroprotection; Cell biology; Neurodegeneration; Receptor; Biochemistry; Neuroscience; Medicine","score_opus":0.03778581350090639,"score_gpt":0.2739141659618432,"score_spread":0.23612835246093683,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018631267","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9812743,0.004349254,0.009987237,0.0004682732,0.000047018148,0.00008834082,0.00026805763,0.0001166397,0.0034008669],"genre_scores_gemma":[0.9911576,0.002314623,0.0033200518,0.00012799891,0.000011867008,0.000040837156,0.00028425382,0.000010052035,0.0027327351],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998523,0.000020686271,0.000010063499,0.000032580654,0.000045760808,0.000038644022],"domain_scores_gemma":[0.99995565,0.000006045739,0.000011305673,0.0000063392836,0.000013048926,0.000007647066],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012339317,0.00034569125,0.00023105087,0.00016450294,0.00022662616,0.0003212472,0.00024629882,0.00046025414,0.0007406129],"category_scores_gemma":[0.000080135746,0.0001468757,0.00044903823,0.00009067313,0.0002990228,0.0002691369,0.0003997758,0.0004437668,0.00035458454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011142067,0.00001124071,0.00045436245,0.00007306651,0.000010914421,0.0003586761,0.000023857026,0.00004746211,0.99725527,0.00026438,0.00007344943,0.001316009],"study_design_scores_gemma":[0.000050431954,0.00023517173,0.018380225,0.000018480972,0.000037245678,0.0028931142,0.00013716189,0.003008225,0.96936506,0.00031237095,0.0055399,0.000022690961],"about_ca_topic_score_codex":0.0013567138,"about_ca_topic_score_gemma":0.0010373677,"teacher_disagreement_score":0.0013567138,"about_ca_system_score_codex":0.00059947016,"about_ca_system_score_gemma":0.00023352764,"threshold_uncertainty_score":0.0043495297},"labels":[],"label_agreement":null},{"id":"W2018664280","doi":"10.1371/journal.pone.0075113","title":"ß1 Integrin Binding Phosphorylates Ezrin at T567 to Activate a Lipid Raft Signalsome Driving Invadopodia Activity and Invasion","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Associazione Italiana per la Ricerca sul Cancro; University of Toronto; American Society of Nephrology","keywords":"Invadopodia; Ezrin; Cell biology; Lipid raft; Phosphorylation; Integrin; Actin cytoskeleton; Cytoskeleton; Extracellular matrix; Chemistry; Proto-oncogene tyrosine-protein kinase Src; Biology; Signal transduction; Cancer cell; Cell; Biochemistry; Cancer","score_opus":0.027282519203485837,"score_gpt":0.22053067425656922,"score_spread":0.19324815505308338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2018664280","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99752694,0.000503773,0.0006691568,0.00007703821,0.000012104511,0.000008618811,0.000096529104,0.000018102151,0.0010876652],"genre_scores_gemma":[0.99737775,0.00040678357,0.00042256602,0.000035914738,0.0000057535462,0.000010588226,0.00019498804,0.000005016801,0.0015407093],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995065,0.000004449455,0.00000289668,0.000009533403,0.000009295667,0.000023233042],"domain_scores_gemma":[0.99997425,0.0000027422775,0.000008341334,0.0000020677858,0.000002907423,0.000009749516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004083324,0.00020044416,0.00011819455,0.000077921686,0.00013970745,0.00018312983,0.0000783848,0.00014602943,0.001533044],"category_scores_gemma":[0.000058172154,0.00009727037,0.00021677602,0.00006262438,0.00008419588,0.00014099006,0.00018255746,0.0002892938,0.00045639923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007575264,0.000007979292,0.00019741866,0.000015790414,0.0000031775014,0.000069189395,0.000007013297,0.000030338082,0.9990582,0.00009709908,0.00003914595,0.00039889215],"study_design_scores_gemma":[0.00002144085,0.000082413535,0.014276762,0.0000052911037,0.000012894338,0.0004072798,0.000042599495,0.0014499278,0.98176724,0.000105939114,0.0018239084,0.0000044591525],"about_ca_topic_score_codex":0.00039135656,"about_ca_topic_score_gemma":0.00050523883,"teacher_disagreement_score":0.001533044,"about_ca_system_score_codex":0.00022784552,"about_ca_system_score_gemma":0.00008477077,"threshold_uncertainty_score":0.005128503},"labels":[],"label_agreement":null},{"id":"W2019689527","doi":"10.1371/journal.pbio.1000439","title":"Structural and Biochemical Characterization of the Human Cyclophilin Family of Peptidyl-Prolyl Isomerases","year":2010,"lang":"en","type":"article","venue":"PLoS Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":306,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Canadian Institutes of Health Research; Basic Energy Sciences; Knut och Alice Wallenbergs Stiftelse; Karolinska Institutet; Office of Science; Stiftelsen för Strategisk Forskning; Ontario Genomics Institute; Ontario Genomics; Genome Canada; GlaxoSmithKline; Ontario Innovation Trust; Wellcome Trust; U.S. Department of Energy","keywords":"Cyclophilin; Isomerase; Peptidylprolyl isomerase; Prolyl isomerase; Cis-trans-Isomerases; Cyclophilin A; Biology; Gene isoform; Biochemistry; Enzyme; PIN1; Molecular biology; Gene","score_opus":0.012262625459061635,"score_gpt":0.2441151649004988,"score_spread":0.2318525394414372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2019689527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99626046,0.0012814311,0.0009339322,0.00006078029,0.0000049140867,0.00001177498,0.00069816795,0.00001444438,0.00073421805],"genre_scores_gemma":[0.99010676,0.0012040142,0.0040528066,0.000058991973,0.0000106552,0.000012293874,0.0036742517,0.000009816021,0.00087042135],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999449,0.0000099555,0.000004714878,0.000012581956,0.000016784192,0.000010959827],"domain_scores_gemma":[0.9999194,0.000012305874,0.0000196018,0.000010163947,0.000012444118,0.000026133852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009192084,0.00025625015,0.00018535682,0.00019013285,0.00009597383,0.0001886481,0.00015480956,0.00014341746,0.0005257645],"category_scores_gemma":[0.00014980427,0.00009403626,0.00022097204,0.0002256049,0.00010314361,0.00010243945,0.000094270676,0.0002143142,0.00018809095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002833497,0.0000413764,0.0035224066,0.00006314529,0.000021402875,0.0002846104,0.000034601027,0.0010815137,0.989193,0.00019930059,0.000120199315,0.0051549952],"study_design_scores_gemma":[0.00005907217,0.0006160799,0.078964554,0.000020484105,0.000085002044,0.0021696356,0.00010913282,0.008735677,0.89863247,0.00029239763,0.010294842,0.000020780764],"about_ca_topic_score_codex":0.0014221857,"about_ca_topic_score_gemma":0.0014367932,"teacher_disagreement_score":0.0014221857,"about_ca_system_score_codex":0.0002685325,"about_ca_system_score_gemma":0.00026506372,"threshold_uncertainty_score":0.0028277636},"labels":[],"label_agreement":null},{"id":"W2020010602","doi":"10.1007/s11010-005-3072-6","title":"CK2 interacting proteins: Emerging paradigms for CK2 regulation?","year":2005,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Casein kinase 2; Phosphorylation; Cell biology; Biology; Kinase; Protein kinase A; Protein phosphorylation; Computational biology; Mitogen-activated protein kinase kinase","score_opus":0.006578867394386393,"score_gpt":0.24246244830683908,"score_spread":0.23588358091245268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020010602","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.1477258,0.6524391,0.06965832,0.08551522,0.0045448784,0.00008069372,0.0006637675,0.00086400256,0.038508195],"genre_scores_gemma":[0.69542116,0.26125437,0.015192522,0.012805971,0.004901765,0.0001938718,0.0007764484,0.000110597204,0.009343355],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961436,0.00006838785,0.00002385258,0.00008416663,0.000076368226,0.00013282541],"domain_scores_gemma":[0.99960274,0.00008666727,0.00007696416,0.00005545393,0.00006440122,0.000113787224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001434939,0.0010129126,0.0013690132,0.00064173073,0.00069837744,0.0040479526,0.0014045025,0.0020821018,0.0033184546],"category_scores_gemma":[0.0010084588,0.00033762856,0.00045108824,0.0007918865,0.0025551734,0.0061615705,0.0011972232,0.0029015779,0.0015141597],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005658496,0.00037037465,0.0067615835,0.0022062846,0.00029523417,0.003126339,0.0010235163,0.0023211828,0.3008898,0.32710087,0.043649755,0.30659655],"study_design_scores_gemma":[0.00034619423,0.0006294065,0.013949555,0.0007496538,0.00036907961,0.0071906974,0.0029008968,0.012114109,0.123463765,0.3778174,0.46019372,0.0002755414],"about_ca_topic_score_codex":0.00032870114,"about_ca_topic_score_gemma":0.0004817969,"teacher_disagreement_score":0.0040479526,"about_ca_system_score_codex":0.0011719201,"about_ca_system_score_gemma":0.00069810497,"threshold_uncertainty_score":0.011101365},"labels":[],"label_agreement":null},{"id":"W2020353856","doi":"10.1110/ps.41301","title":"pH‐induced conformational transitions of a molten–globule–like state of the inhibitory prodomain of furin: Implications for zymogen activation","year":2001,"lang":"en","type":"article","venue":"Protein Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Montreal Clinical Research Institute; Biotechnology Research Institute","funders":"Medical Research Council; Medical Research Council Canada; Government of Canada","keywords":"Furin; Chemistry; Zymogen; Cleavage (geology); Stereochemistry; Proprotein convertase; Amino acid; Residue (chemistry); Crystallography; Enzyme; Biochemistry; Biology","score_opus":0.022441915179113314,"score_gpt":0.27414377777447935,"score_spread":0.25170186259536603,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020353856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977851,0.00025423235,0.0013825716,0.000043358603,0.000006937621,0.000009196684,0.00005929907,0.000017721226,0.00044168116],"genre_scores_gemma":[0.9992899,0.00011139507,0.0003346191,0.000025855918,0.0000030010199,0.0000053012564,0.000064104446,0.0000047412555,0.00016116792],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999682,0.000004506407,0.0000017065905,0.000008185661,0.000007476922,0.000009928217],"domain_scores_gemma":[0.9999318,0.000014933781,0.000024809548,0.0000048835386,0.000007732515,0.000015832686],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008474758,0.00019797569,0.000113777714,0.000059447746,0.00011821632,0.00018925418,0.0001794542,0.00018382314,0.0010375121],"category_scores_gemma":[0.00015362933,0.00008179888,0.00011459129,0.00006457299,0.0003274831,0.00031215063,0.00010990686,0.00032639748,0.0001619996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018840616,0.00003429927,0.0007598165,0.000021771006,0.0000067902547,0.00016809322,0.00006784666,0.00031029023,0.9972102,0.00027486077,0.000030593576,0.0009269547],"study_design_scores_gemma":[0.000032035856,0.00048201598,0.020471802,0.000009081864,0.000012976705,0.00045712147,0.00013974735,0.0057314257,0.9708642,0.0006297274,0.0011497644,0.000020228223],"about_ca_topic_score_codex":0.00017542446,"about_ca_topic_score_gemma":0.00009811447,"teacher_disagreement_score":0.0010375121,"about_ca_system_score_codex":0.0001496565,"about_ca_system_score_gemma":0.00006418842,"threshold_uncertainty_score":0.003470838},"labels":[],"label_agreement":null},{"id":"W2020569068","doi":"10.1089/scd.2008.0064","title":"Tamoxifen-Inducible Cre-Mediated Calreticulin Excision to Study Mouse Embryonic Stem Cell Differentiation","year":2008,"lang":"en","type":"article","venue":"Stem Cells and Development","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Calreticulin; Stem cell; Cell biology; Embryonic stem cell; Cre recombinase; Cellular differentiation; Tamoxifen; Cre-Lox recombination; Gene targeting; Endoplasmic reticulum; Gene; Genetics; Transgene","score_opus":0.020048337444241643,"score_gpt":0.2240990211029007,"score_spread":0.20405068365865905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020569068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7683302,0.016631354,0.18979385,0.0013412233,0.00075223186,0.0014445198,0.004407321,0.0017035764,0.015595657],"genre_scores_gemma":[0.8032618,0.015672686,0.13198723,0.00064272364,0.00015146457,0.001638431,0.005310033,0.00078413606,0.040551424],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99955684,0.00007630596,0.00005769211,0.00010890036,0.00013722961,0.00006296752],"domain_scores_gemma":[0.9997272,0.00006688782,0.00007043624,0.000046610687,0.000035238532,0.0000535513],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000562888,0.0006008676,0.0005019779,0.0010516595,0.00033321715,0.00036260925,0.0006216075,0.0007296511,0.0033123535],"category_scores_gemma":[0.00024618825,0.00039558386,0.0004464677,0.00046703257,0.0005226787,0.000525876,0.00040430087,0.0014549368,0.0016282472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023598817,0.000023018825,0.000054629185,0.000034506644,0.000003113388,0.000057256242,0.000026258456,0.00003064925,0.99775106,0.00032865154,0.000064545755,0.0016026938],"study_design_scores_gemma":[0.000046582543,0.0001668707,0.0010814589,0.000013024694,0.000025808999,0.00045634378,0.00002525977,0.0006380102,0.9836242,0.00012740906,0.013787771,0.0000072500184],"about_ca_topic_score_codex":0.00053209084,"about_ca_topic_score_gemma":0.00096804,"teacher_disagreement_score":0.0033123535,"about_ca_system_score_codex":0.0003975046,"about_ca_system_score_gemma":0.0002875408,"threshold_uncertainty_score":0.011080921},"labels":[],"label_agreement":null},{"id":"W2020685795","doi":"10.1016/j.mcn.2007.08.001","title":"Combined activation of calpain and calcineurin during ligand-induced growth cone collapse","year":2007,"lang":"en","type":"article","venue":"Molecular and Cellular Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Biology; Calcineurin; Calpain; Cone (formal languages); Cell biology; Ligand (biochemistry); Growth cone; Receptor; Internal medicine; Biochemistry; Transplantation","score_opus":0.009452611917070412,"score_gpt":0.22752905376397337,"score_spread":0.21807644184690295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020685795","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936652,0.0014723673,0.0012197824,0.00018340744,0.000077151344,0.000050769304,0.00037834173,0.00009025275,0.0028626847],"genre_scores_gemma":[0.99651945,0.00030802927,0.00083416566,0.00009364825,0.000021709397,0.000046609002,0.00033768476,0.00002211426,0.0018164915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938047,0.00007538482,0.000042236592,0.000062502055,0.00018343834,0.00025587258],"domain_scores_gemma":[0.99945635,0.0001800856,0.00006233369,0.00006777779,0.000056761535,0.00017677329],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036243023,0.0004270021,0.0005789111,0.0004154922,0.000488585,0.0008014197,0.0005416408,0.0007909642,0.0020046723],"category_scores_gemma":[0.00065767905,0.00028623967,0.00054473535,0.0003626466,0.00053652894,0.00063396804,0.0005653748,0.0015789572,0.0003607432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010725508,0.0000703068,0.00015991494,0.000036373396,0.000015280764,0.00023004529,0.000042447016,0.00012387877,0.99708146,0.00024762232,0.0001132348,0.000806771],"study_design_scores_gemma":[0.000066294124,0.0002655062,0.005787005,0.00001037337,0.000018186032,0.00025602613,0.00009228559,0.0022194732,0.9904295,0.00010343898,0.00073822064,0.000013811856],"about_ca_topic_score_codex":0.0057875924,"about_ca_topic_score_gemma":0.011638899,"teacher_disagreement_score":0.0057875924,"about_ca_system_score_codex":0.0014476618,"about_ca_system_score_gemma":0.0007183891,"threshold_uncertainty_score":0.011507809},"labels":[],"label_agreement":null},{"id":"W2020695579","doi":"10.1021/ja0570279","title":"Functional Dynamics of Human FKBP12 Revealed by Methyl <sup>13</sup>C Rotating Frame Relaxation Dispersion NMR Spectroscopy","year":2006,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National High Magnetic Field Laboratory; University of Texas Southwestern Medical Center","keywords":"Chemistry; Nuclear magnetic resonance spectroscopy; Relaxation (psychology); Substrate (aquarium); Microsecond; Folding (DSP implementation); Molecular dynamics; Protein dynamics; Crystallography; Spectroscopy; Side chain; Chemical physics; Dispersion (optics); Stereochemistry; Computational chemistry","score_opus":0.005905215615945446,"score_gpt":0.24367541288962294,"score_spread":0.23777019727367749,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020695579","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99418396,0.00051900494,0.004325402,0.00008079351,0.0000068370864,0.0000054726584,0.00021850287,0.000060190323,0.0005997585],"genre_scores_gemma":[0.9951054,0.00028934822,0.0034037384,0.000027671444,0.0000046134687,0.000015649968,0.00029697077,0.000017072594,0.00083962403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99996805,0.0000053250983,0.0000014118506,0.000007730502,0.000010984315,0.0000064889223],"domain_scores_gemma":[0.99991906,0.000023562858,0.000019841687,0.0000094410525,0.000016889247,0.0000112554935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009369067,0.00013719652,0.000100716694,0.00010301947,0.00013929895,0.00009937385,0.00011647279,0.00016733444,0.0007238994],"category_scores_gemma":[0.0002285156,0.000086788496,0.00006663278,0.00010792002,0.00013195211,0.00011245682,0.00006561551,0.00020613296,0.00020211536],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000111568675,0.00000618965,0.00045266296,0.000015241044,0.0000030680112,0.00002954159,0.00002670095,0.00016382354,0.9970765,0.00007199556,0.00005828165,0.0019843658],"study_design_scores_gemma":[0.000022470193,0.00025361165,0.041304693,0.0000074421273,0.000018717126,0.00053924357,0.000058723675,0.01024456,0.9448369,0.00020214324,0.0024927116,0.00001880356],"about_ca_topic_score_codex":0.0011001261,"about_ca_topic_score_gemma":0.0009308853,"teacher_disagreement_score":0.0011001261,"about_ca_system_score_codex":0.00019913622,"about_ca_system_score_gemma":0.00007186376,"threshold_uncertainty_score":0.002421677},"labels":[],"label_agreement":null},{"id":"W2020748529","doi":"10.1007/s00547-005-2005-2","title":"Involvement of calcineurin in ischemic myocardial damage","year":2006,"lang":"en","type":"article","venue":"International Journal of Angiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Medicine; Calcineurin; Angiology; Cardiology; Internal medicine; Transplantation","score_opus":0.008334549956221233,"score_gpt":0.26322438048614,"score_spread":0.25488983052991876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020748529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8560376,0.13338159,0.0020774214,0.00061032287,0.000116031915,0.0000532918,0.0000802596,0.00009301135,0.0075503914],"genre_scores_gemma":[0.9812773,0.016545154,0.00056317315,0.00010979086,0.0001301029,0.000015785454,0.000062799816,0.0000044021463,0.0012915533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989223,0.000023381002,0.00001016846,0.000015933696,0.000031718202,0.000026640033],"domain_scores_gemma":[0.99981266,0.000033353997,0.00006315319,0.000018320214,0.000025670011,0.00004687153],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003517582,0.00035248147,0.000331152,0.0006234896,0.00028600343,0.0003656195,0.00028604927,0.00051283,0.0007933877],"category_scores_gemma":[0.00036161402,0.000118678596,0.00013695183,0.0002262203,0.00043091123,0.00034342537,0.0002596482,0.00034115242,0.00010128484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015336812,0.00025624837,0.0066276486,0.00070564303,0.00007819167,0.0034091426,0.0002490608,0.0003151097,0.94935244,0.002259696,0.00034117786,0.03487197],"study_design_scores_gemma":[0.00037269865,0.0036463826,0.2436606,0.0002994492,0.00047136148,0.015332439,0.0005109286,0.0037930715,0.7041781,0.0074774153,0.020204805,0.00005269323],"about_ca_topic_score_codex":0.00039623055,"about_ca_topic_score_gemma":0.00041930302,"teacher_disagreement_score":0.0007933877,"about_ca_system_score_codex":0.00038921277,"about_ca_system_score_gemma":0.00023186057,"threshold_uncertainty_score":0.0028240085},"labels":[],"label_agreement":null},{"id":"W2020985561","doi":"10.1016/j.jmb.2010.08.001","title":"Dissecting the Microscopic Steps of the Cyclophilin A Enzymatic Cycle on the Biological HIV-1 Capsid Substrate by NMR","year":2010,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Basic Energy Sciences; U.S. Department of Energy; Howard Hughes Medical Institute","keywords":"Cyclophilin A; Isomerase; Cyclophilin; Capsid; Active site; Biochemistry; Enzyme; Mutagenesis; Prolyl isomerase; Enzyme kinetics; Mutant; Peptidylprolyl isomerase; Conformational change; Heteronuclear single quantum coherence spectroscopy; Catalytic cycle; Biology; Chemistry; Nuclear magnetic resonance spectroscopy; Stereochemistry; Molecular biology","score_opus":0.008425893647420545,"score_gpt":0.25690619726399694,"score_spread":0.2484803036165764,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2020985561","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98221093,0.0005199146,0.00990806,0.00048394353,0.000029799534,0.00001929596,0.00007629153,0.000079999285,0.0066715847],"genre_scores_gemma":[0.9943374,0.00045260202,0.0037158006,0.000059891936,0.000011380866,0.000013968618,0.000046375404,0.00001761115,0.001345004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999713,0.0000045148695,7.5470035e-7,0.000005040569,0.00000750618,0.000010938292],"domain_scores_gemma":[0.999913,0.000049087,0.000010077932,0.00001175129,0.0000075054986,0.000008563003],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011898058,0.00018534306,0.00011000657,0.00011509843,0.00040084886,0.00032422837,0.00030568245,0.00030382615,0.0021848048],"category_scores_gemma":[0.00021517643,0.00019406987,0.00012500903,0.0000859722,0.0003712725,0.0005661384,0.00019370383,0.00091519946,0.0002404438],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001649582,0.000037515005,0.000600516,0.00007270822,0.000012067145,0.00026853534,0.00012126414,0.003480643,0.98452234,0.005965171,0.00039395384,0.004360233],"study_design_scores_gemma":[0.00007657475,0.0003552016,0.0070060315,0.000025582589,0.000024048002,0.00047522207,0.00038593812,0.08795908,0.8927891,0.0053393366,0.005510105,0.000053895463],"about_ca_topic_score_codex":0.0012306115,"about_ca_topic_score_gemma":0.0019123635,"teacher_disagreement_score":0.0021848048,"about_ca_system_score_codex":0.00042097812,"about_ca_system_score_gemma":0.00020506007,"threshold_uncertainty_score":0.0073089004},"labels":[],"label_agreement":null},{"id":"W2021978386","doi":"10.1074/jbc.m113.479964","title":"Structure and Activity of the Peptidyl-Prolyl Isomerase Domain from the Histone Chaperone Fpr4 toward Histone H3 Proline Isomerization","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Chaperone (clinical); Chemistry; Proline; Histone; Isomerization; Isomerase; Prolyl isomerase; Histone H3; Biochemistry; Enzyme; DNA; Catalysis; PIN1; Amino acid","score_opus":0.013419056388592254,"score_gpt":0.2464721112823056,"score_spread":0.23305305489371334,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2021978386","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99794704,0.00042751664,0.00087438454,0.000040017756,0.0000049231853,0.0000042953197,0.00019358567,0.000012922589,0.0004953232],"genre_scores_gemma":[0.9963652,0.000354368,0.0009630544,0.000027217886,0.0000047839335,0.000005265083,0.0010989815,0.000008510889,0.00117251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994576,0.000009970197,0.000003152985,0.000011324834,0.000013636056,0.000016312333],"domain_scores_gemma":[0.9999429,0.000010186029,0.00001450178,0.0000042954102,0.000011797264,0.000016244167],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008538753,0.00020304929,0.00014793803,0.00010046748,0.00012078973,0.0001786477,0.00026802273,0.00015478476,0.0005556279],"category_scores_gemma":[0.00015785731,0.00008576847,0.00017585371,0.00011518792,0.00014445065,0.000117771095,0.00009479243,0.0002834758,0.00022524728],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003214619,0.000027845439,0.000536674,0.0000365571,0.000009108881,0.00007289701,0.000017107552,0.00070721254,0.99665797,0.00020196848,0.00005145569,0.0013597121],"study_design_scores_gemma":[0.000025529465,0.00018989926,0.0048733717,0.0000054975853,0.00001633825,0.00020407928,0.000022151213,0.00401942,0.98901224,0.00008268321,0.0015380557,0.000010647016],"about_ca_topic_score_codex":0.0017661798,"about_ca_topic_score_gemma":0.00088887307,"teacher_disagreement_score":0.0017661798,"about_ca_system_score_codex":0.0004244379,"about_ca_system_score_gemma":0.00019901132,"threshold_uncertainty_score":0.003511846},"labels":[],"label_agreement":null},{"id":"W2022275019","doi":"10.1002/eji.201040313","title":"HPK1 competes with ADAP for SLP‐76 binding and <i>via</i> Rap1 negatively affects T‐cell adhesion","year":2010,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Biology; Rap1; Cell biology; Adhesion; Cell adhesion; Cell; Genetics; Chemistry; Signal transduction","score_opus":0.00686420898688964,"score_gpt":0.20550916978079534,"score_spread":0.1986449607939057,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022275019","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960211,0.0014423988,0.0007650312,0.00013436175,0.000032467764,0.000010850434,0.00021990346,0.000046728437,0.0013272511],"genre_scores_gemma":[0.99686337,0.00053501653,0.00063543575,0.000052404906,0.000012750895,0.000021682143,0.00031898098,0.000011381836,0.0015491806],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999813,0.00003615561,0.000015886522,0.000039202514,0.00003915308,0.000056526664],"domain_scores_gemma":[0.9999362,0.000013706788,0.000015888814,0.000008147727,0.0000048465354,0.000021189924],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009652921,0.00038027097,0.0002568401,0.0001103758,0.00019249345,0.00021775505,0.00030113355,0.0002140169,0.0027638937],"category_scores_gemma":[0.00011704428,0.00014564118,0.00020267848,0.00008127839,0.00019139389,0.00019506703,0.00020952857,0.0005937619,0.00060241873],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029495193,0.000053150598,0.00016277317,0.000058231053,0.000009620966,0.00004980006,0.0000069665634,0.0000723515,0.9981414,0.00008756836,0.00009803553,0.0009651932],"study_design_scores_gemma":[0.000016090364,0.00018117894,0.0024456922,0.0000026887362,0.0000095307705,0.00023801652,0.000008676617,0.0006226697,0.9953111,0.000020921427,0.0011403973,0.000003047121],"about_ca_topic_score_codex":0.00046776302,"about_ca_topic_score_gemma":0.0004955348,"teacher_disagreement_score":0.0027638937,"about_ca_system_score_codex":0.000341352,"about_ca_system_score_gemma":0.0001552708,"threshold_uncertainty_score":0.0092461705},"labels":[],"label_agreement":null},{"id":"W2022423993","doi":"10.1016/j.tcm.2006.01.004","title":"Assembling Pieces of the Cardiac Puzzle; Calreticulin and Calcium-Dependent Pathways in Cardiac Development, Health, and Disease","year":2006,"lang":"en","type":"review","venue":"Trends in Cardiovascular Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Faculty of Medicine and Dentistry, University of Alberta; Heart and Stroke Foundation of Canada","keywords":"Calreticulin; Endoplasmic reticulum; Myocardin; GATA6; Cell biology; Biology; Enhancer; Calsequestrin; Calcium-binding protein; Heart development; Transcription factor; Ryanodine receptor; Regulator; Internal medicine; Serum response factor; Medicine; Calcium; Gene; Genetics","score_opus":0.05503087212542188,"score_gpt":0.32584661218272326,"score_spread":0.27081574005730136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2022423993","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00006685412,0.9972881,0.00018785032,0.0013062814,0.00049135304,0.0000020528516,0.000010333995,0.000009388611,0.0006377525],"genre_scores_gemma":[0.00031917143,0.99755365,0.00026921462,0.000541784,0.000580931,0.0000036761323,0.00001902147,0.0000016901687,0.0007108968],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997733,0.000037181642,0.000028154052,0.000040320512,0.0001001359,0.000021001437],"domain_scores_gemma":[0.9994248,0.0002453465,0.000051211933,0.00001773255,0.00016052499,0.00010037152],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010506535,0.0012374535,0.0023725359,0.0020574646,0.00055029785,0.001974978,0.0016903937,0.0023786544,0.0042671463],"category_scores_gemma":[0.001160224,0.0004159053,0.00038782592,0.0027963105,0.0013386613,0.0035793874,0.0011187621,0.0038061498,0.0030106008],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014615891,0.00007062878,0.00021591249,0.006089979,0.000083793646,0.00028110872,0.00012168706,0.00049361034,0.002322724,0.0086903395,0.14065115,0.8408328],"study_design_scores_gemma":[0.000024749766,0.000032532644,0.0005736644,0.0014192042,0.000047554295,0.0006416271,0.00011905611,0.00011787909,0.00021314308,0.006489722,0.9903015,0.000019464811],"about_ca_topic_score_codex":0.0017354913,"about_ca_topic_score_gemma":0.0045906636,"teacher_disagreement_score":0.0042671463,"about_ca_system_score_codex":0.0011178135,"about_ca_system_score_gemma":0.0014156247,"threshold_uncertainty_score":0.014275074},"labels":[],"label_agreement":null},{"id":"W2025371598","doi":"10.1016/s0952-7915(02)00334-5","title":"Communication between the TCR and integrins: role of the molecular adapter ADAP/Fyb/Slap","year":2002,"lang":"en","type":"review","venue":"Current Opinion in Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Amgen (Canada); University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs; Amgen","keywords":"T-cell receptor; Integrin; Cell biology; Signal transducing adaptor protein; Biology; Avidity; Immunological synapse; Signal transduction; Adapter (computing); Integrin alpha M; T cell; Antigen; Receptor; Immunology; Immune system; Genetics","score_opus":0.06349847651208046,"score_gpt":0.3414832879082195,"score_spread":0.27798481139613906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025371598","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00043780424,0.9955907,0.0007403061,0.00095697533,0.001073634,0.0000061147052,0.000020150403,0.000020730335,0.0011535359],"genre_scores_gemma":[0.0021565265,0.9939446,0.0006755065,0.0007002936,0.0009732025,0.000011453345,0.000059778875,0.0000030290803,0.0014755888],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997501,0.000028886252,0.00003343254,0.000064582695,0.0000887081,0.000034289602],"domain_scores_gemma":[0.9996375,0.00013375707,0.000054959735,0.000011857991,0.00009343644,0.000068497655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010846402,0.0013516878,0.0020012113,0.0009879058,0.00036553634,0.0018181128,0.0018962484,0.0025420045,0.0023891293],"category_scores_gemma":[0.00064295967,0.00036938215,0.00037869762,0.0015064698,0.00097533275,0.002860749,0.0007307491,0.0026457792,0.0033433947],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037702895,0.00006616339,0.00024401685,0.00690006,0.00009160419,0.0007456522,0.00007270917,0.0005193224,0.01663591,0.0064724195,0.0413195,0.9265556],"study_design_scores_gemma":[0.0000824314,0.00012503471,0.0010789589,0.0010018911,0.00014169195,0.0023724309,0.00015093907,0.00024559814,0.0033122215,0.003978847,0.98747474,0.00003524685],"about_ca_topic_score_codex":0.00080429285,"about_ca_topic_score_gemma":0.0011646015,"teacher_disagreement_score":0.0025420045,"about_ca_system_score_codex":0.000934947,"about_ca_system_score_gemma":0.0011892663,"threshold_uncertainty_score":0.007992446},"labels":[],"label_agreement":null},{"id":"W2025834688","doi":"10.1016/j.neuroscience.2008.11.004","title":"Calcineurin inhibition eliminates the normal inverted U curve, enhances acquisition and prolongs memory in a mammalian 3′-5′-cyclic AMP–dependent learning paradigm","year":2008,"lang":"en","type":"article","venue":"Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Calcineurin; Neuroscience; CREB; Long-term potentiation; Dephosphorylation; Phosphatase; Conditioned place preference; Hippocampal formation; Chemistry; Psychology; Phosphorylation; Biochemistry; Medicine; Internal medicine; Transcription factor; Receptor; Transplantation; Dopamine","score_opus":0.018192806366779047,"score_gpt":0.24930227680380143,"score_spread":0.23110947043702237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2025834688","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99310243,0.0006308381,0.0024917459,0.0002912,0.00014049465,0.000034375793,0.0002688361,0.00040873745,0.002631385],"genre_scores_gemma":[0.98908615,0.0006367945,0.0033567,0.00014425577,0.000051028113,0.00006862479,0.00039969946,0.0001784111,0.0060782596],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999587,0.00003682735,0.000041784773,0.00008387252,0.00011823691,0.00013222384],"domain_scores_gemma":[0.99884653,0.0001983108,0.00030073564,0.00025771136,0.00008310759,0.00031351915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003214528,0.0007613385,0.0007311539,0.00089669833,0.00044663352,0.0007212256,0.0015030891,0.00070731196,0.0032140515],"category_scores_gemma":[0.0006632737,0.00033125497,0.0005985116,0.0004352244,0.0011836201,0.0010626485,0.0005645628,0.0030270952,0.00075683487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072315894,0.00030195471,0.000111194,0.00003370548,0.000010835019,0.00008573212,0.00004289352,0.00012031897,0.9937575,0.00056955277,0.00016540325,0.0040778667],"study_design_scores_gemma":[0.00004990406,0.0007684685,0.0014311456,0.000008005555,0.000015263513,0.0001477182,0.000033843957,0.0010440492,0.9952551,0.00038801436,0.00084352726,0.000014829926],"about_ca_topic_score_codex":0.00213859,"about_ca_topic_score_gemma":0.0034725217,"teacher_disagreement_score":0.0032140515,"about_ca_system_score_codex":0.0008270974,"about_ca_system_score_gemma":0.0010713291,"threshold_uncertainty_score":0.010752082},"labels":[],"label_agreement":null},{"id":"W2027058522","doi":"10.1016/s0041-1345(00)01976-x","title":"The role of ezrin in T-cell receptor-dependent signaling","year":2001,"lang":"en","type":"article","venue":"Transplantation Proceedings","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Western University","funders":"","keywords":"Signal transduction; Cell biology; Receptor; Ezrin; Biology; Immunology; Chemistry; Cancer research; Cell; Genetics; Cytoskeleton","score_opus":0.00665027752001215,"score_gpt":0.22080415148088625,"score_spread":0.2141538739608741,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027058522","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8526155,0.08258374,0.022853537,0.0071625314,0.00071961,0.00005059693,0.0002301508,0.000290782,0.03349363],"genre_scores_gemma":[0.976177,0.013376473,0.0022213699,0.00021988688,0.0001717515,0.000015191319,0.00008596182,0.000016790069,0.00771557],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987376,0.000022249045,0.0000070785813,0.000018966406,0.000031475265,0.000046459783],"domain_scores_gemma":[0.99993026,0.00001484521,0.000010762149,0.000008686412,0.000011931214,0.000023553146],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027848777,0.00034041086,0.00024542797,0.0003690265,0.0005729855,0.001209035,0.00028362204,0.0006169245,0.0013448347],"category_scores_gemma":[0.00022016572,0.00013290562,0.00016067599,0.00019613326,0.00056933996,0.0008771206,0.0004186941,0.0011440417,0.0004705792],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00072591886,0.000067028814,0.0009541578,0.00016019927,0.000026283355,0.0013941437,0.00012740011,0.0005618991,0.935697,0.028792584,0.0015391367,0.029954115],"study_design_scores_gemma":[0.0001087652,0.0003108553,0.016075121,0.000048519658,0.0000764945,0.0037804106,0.00036096384,0.0048279525,0.8820062,0.014209187,0.078155555,0.000039831903],"about_ca_topic_score_codex":0.00039161256,"about_ca_topic_score_gemma":0.0005906927,"teacher_disagreement_score":0.0013448347,"about_ca_system_score_codex":0.00079037866,"about_ca_system_score_gemma":0.00024215248,"threshold_uncertainty_score":0.005734563},"labels":[],"label_agreement":null},{"id":"W2027923622","doi":"10.1074/jbc.m114.616680","title":"ClipR-59 Interacts with Elmo2 and Modulates Myoblast Fusion","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health","keywords":"C2C12; Cell biology; Myocyte; Gene knockdown; Cell fusion; Fusion protein; Biology; GTPase; Motility; Chemistry; Cell; Myogenesis; Genetics; Cell culture; Gene","score_opus":0.025308795398486662,"score_gpt":0.255310822804738,"score_spread":0.23000202740625134,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2027923622","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99329764,0.0026251252,0.0013217991,0.0001549921,0.000042278592,0.000017288432,0.00040314344,0.00008128424,0.0020563933],"genre_scores_gemma":[0.9944372,0.00080562156,0.0008794258,0.00012511013,0.000014669808,0.000022569115,0.00087756204,0.000029446455,0.002808378],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997017,0.00003718352,0.000021931979,0.00008352627,0.00007733342,0.0000783544],"domain_scores_gemma":[0.9998772,0.000011281501,0.000040498668,0.000007621327,0.00000851981,0.000054921722],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013612963,0.00030797435,0.000401074,0.00024326392,0.00032571706,0.00034458487,0.00024548298,0.00042070152,0.0019996492],"category_scores_gemma":[0.00014252301,0.00018650226,0.0003126641,0.00013061377,0.00022231627,0.0001821909,0.00044987947,0.0004975067,0.0008607043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006597196,0.000009675675,0.0001474033,0.000020509617,0.000004208041,0.00008395208,0.000004940871,0.000015565143,0.9993051,0.000028238645,0.00003713787,0.00027722123],"study_design_scores_gemma":[0.00002496424,0.00014654762,0.021416014,0.000009025657,0.000021349199,0.0006787806,0.00005398059,0.0012391392,0.97213745,0.000030193629,0.0042343233,0.00000835503],"about_ca_topic_score_codex":0.00041907144,"about_ca_topic_score_gemma":0.0007705674,"teacher_disagreement_score":0.0019996492,"about_ca_system_score_codex":0.0004105954,"about_ca_system_score_gemma":0.00011211601,"threshold_uncertainty_score":0.006689489},"labels":[],"label_agreement":null},{"id":"W2028534230","doi":"10.1160/th04-08-0522","title":"Myocardial extra-cellular matrix and its regulation by metalloproteinases and their inhibitors","year":2005,"lang":"en","type":"review","venue":"Thrombosis and Haemostasis","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"","keywords":"Matrix metalloproteinase; Medicine; Matrix (chemical analysis); Cell biology; Cardiology; Computational biology; Biology; Internal medicine; Chemistry","score_opus":0.05592619677942941,"score_gpt":0.3262814431857945,"score_spread":0.2703552464063651,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2028534230","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017453534,0.9981335,0.00023292059,0.00018367183,0.00022038897,0.000004276138,0.000013406543,0.000008333319,0.0010290188],"genre_scores_gemma":[0.0010944138,0.996671,0.000309435,0.0001263262,0.00018845052,0.0000090628855,0.000028064977,0.0000016813681,0.0015716617],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99980944,0.000024169762,0.000027515687,0.000034232595,0.000084765765,0.000019924913],"domain_scores_gemma":[0.9997768,0.000069078495,0.00003525171,0.000010832262,0.000077211,0.000030753654],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053975586,0.0009591696,0.0013501554,0.0016372598,0.00031723618,0.0009922755,0.0008758202,0.0011539056,0.0023910792],"category_scores_gemma":[0.0005242489,0.0003305915,0.00035138213,0.0016791231,0.0005168183,0.0012906067,0.0005156268,0.001397611,0.003604329],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001304807,0.00008808522,0.0002655009,0.0056990483,0.00007315457,0.00041094335,0.000055514345,0.00036386578,0.007635502,0.0038604995,0.031613905,0.9498035],"study_design_scores_gemma":[0.00002608133,0.00009583963,0.0010283818,0.00058066513,0.000047821406,0.001607025,0.00004165206,0.00009309963,0.002206965,0.0015051283,0.9927509,0.000016469005],"about_ca_topic_score_codex":0.0008281612,"about_ca_topic_score_gemma":0.0014367944,"teacher_disagreement_score":0.0023910792,"about_ca_system_score_codex":0.0006078392,"about_ca_system_score_gemma":0.00071776536,"threshold_uncertainty_score":0.007998943},"labels":[],"label_agreement":null},{"id":"W2029306013","doi":"10.1007/s12035-014-8704-y","title":"Aberrant Expression of RCAN1 in Alzheimer’s Pathogenesis: A New Molecular Mechanism and a Novel Drug Target","year":2014,"lang":"en","type":"review","venue":"Molecular Neurobiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Neurofibrillary tangle; Neuroscience; Neuropathology; Senile plaques; Tangle; Pathogenesis; Hyperphosphorylation; Mechanism (biology); Alzheimer's disease; Dementia; Biology; Disease; Medicine; Cell biology; Pathology; Immunology; Phosphorylation","score_opus":0.026057895888964386,"score_gpt":0.2840457888736519,"score_spread":0.2579878929846875,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029306013","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022083113,0.99811125,0.00026808755,0.0003485797,0.00021826004,0.0000044635153,0.000029308247,0.000010739498,0.0007883553],"genre_scores_gemma":[0.0008810212,0.9977717,0.00027535745,0.00018399702,0.00014167835,0.000005895068,0.000040061466,0.0000015989261,0.0006986324],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998857,0.000014170414,0.000014816685,0.000021776748,0.00004833226,0.000015285588],"domain_scores_gemma":[0.9998462,0.00004804534,0.000027050566,0.0000058282,0.0000540449,0.000018888373],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00054078264,0.0010052219,0.001270962,0.0012465329,0.00020846368,0.000897294,0.00095772406,0.0010443397,0.0020063634],"category_scores_gemma":[0.00045316195,0.00024723122,0.00036911777,0.0014218153,0.0005242207,0.0010674701,0.0005738537,0.0019132311,0.0013973308],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016387462,0.000071990464,0.00020879145,0.00857757,0.00011660915,0.0004135447,0.000034126027,0.0005726483,0.0051522283,0.0046247635,0.04029148,0.9397723],"study_design_scores_gemma":[0.000038398444,0.00007483507,0.000665376,0.0012752421,0.00015424361,0.0014342241,0.00003957701,0.00015795109,0.0019410056,0.002414119,0.99177927,0.000025713814],"about_ca_topic_score_codex":0.0010956033,"about_ca_topic_score_gemma":0.0022434902,"teacher_disagreement_score":0.0020063634,"about_ca_system_score_codex":0.0007898799,"about_ca_system_score_gemma":0.0010300134,"threshold_uncertainty_score":0.0067119002},"labels":[],"label_agreement":null},{"id":"W2029766961","doi":"10.1002/glia.20568","title":"Basigin/EMMPRIN/CD147 mediates neuron‐glia interactions in the optic lamina of Drosophila","year":2007,"lang":"en","type":"article","venue":"Glia","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Cancer Institute; National Institute of Neurological Disorders and Stroke; National Eye Institute; National Center for Research Resources; Curtin University of Technology","keywords":"Basigin; Biology; Cell biology; Neurite; Extracellular matrix; Metalloproteinase; Basal lamina; Mutant; Neuroscience; Matrix metalloproteinase; Anatomy; Ultrastructure; Biochemistry; In vitro","score_opus":0.015978010336560673,"score_gpt":0.2818443006521483,"score_spread":0.26586629031558767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029766961","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967867,0.0005198376,0.00095119706,0.000046741796,0.0000065385098,0.0000042764655,0.00006446155,0.000027511593,0.001592716],"genre_scores_gemma":[0.9957878,0.00021993186,0.00089156243,0.000016356275,0.0000024159856,0.000005877907,0.00014923017,0.000010387008,0.002916358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999461,0.000005277922,0.000002619517,0.000009605584,0.000019434368,0.000016928827],"domain_scores_gemma":[0.999959,0.000003113174,0.000010796445,0.0000034713705,0.0000060023335,0.000017646518],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000047308484,0.0002697933,0.000081274666,0.0001294337,0.00016242791,0.00021734726,0.00015189726,0.00018393989,0.0007415056],"category_scores_gemma":[0.000059098995,0.00012520934,0.000092793794,0.00003623404,0.00015658574,0.0001669061,0.00022908629,0.00027525707,0.00042934474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023714769,0.0000032372989,0.00022881682,0.000010433548,0.0000016949546,0.00007646057,0.000007731838,0.000019296967,0.99913317,0.00010740806,0.000018859573,0.0003693089],"study_design_scores_gemma":[0.00001570198,0.00006395093,0.020169958,0.000007650702,0.000013315985,0.00066898926,0.000045157074,0.0016340248,0.9746873,0.00008998209,0.0026011865,0.000002685185],"about_ca_topic_score_codex":0.0011081257,"about_ca_topic_score_gemma":0.0021075194,"teacher_disagreement_score":0.0011081257,"about_ca_system_score_codex":0.00051201385,"about_ca_system_score_gemma":0.000124376,"threshold_uncertainty_score":0.0037149787},"labels":[],"label_agreement":null},{"id":"W2030242756","doi":"10.1523/jneurosci.3092-12.2013","title":"Calcium, Calpain, and Calcineurin in Low-Frequency Depression of Transmitter Release","year":2013,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada; Universiteit Gent; National Science Foundation","keywords":"Calcineurin; Calpain; Calcium; Transmitter; Neuroscience; Depression (economics); Psychology; Chemistry; Biology; Medicine; Computer science; Internal medicine; Telecommunications; Biochemistry; Economics","score_opus":0.014266454282659258,"score_gpt":0.26002826366444276,"score_spread":0.2457618093817835,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030242756","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824117,0.014820121,0.0009855791,0.00014019643,0.000031510812,0.00005586972,0.00008093946,0.000032476084,0.0014416222],"genre_scores_gemma":[0.99432534,0.002795348,0.0010428246,0.00005580106,0.000019548375,0.000044582346,0.00011233694,0.0000038752787,0.001600335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998468,0.000014001266,0.000017726727,0.000036505946,0.000043095813,0.000041796036],"domain_scores_gemma":[0.99984705,0.00001682633,0.000053883145,0.0000105961135,0.000018397743,0.00005330457],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027140134,0.00058061525,0.00057438505,0.00045479755,0.0003061377,0.0004690375,0.00056202756,0.00078048644,0.00062801444],"category_scores_gemma":[0.000239126,0.00030352155,0.00040637972,0.00022408966,0.00050856185,0.00044328478,0.00037199722,0.00080244977,0.00011210917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007417944,0.000084444204,0.0010649316,0.00015974203,0.000019415202,0.0004127694,0.000043046257,0.00009458357,0.994369,0.000115627656,0.000033669214,0.002860995],"study_design_scores_gemma":[0.0007279527,0.0029065784,0.19419993,0.00006347134,0.00021372644,0.003104707,0.00016962242,0.004298611,0.7907187,0.00042446936,0.0031335638,0.000038723396],"about_ca_topic_score_codex":0.0024766545,"about_ca_topic_score_gemma":0.0048466767,"teacher_disagreement_score":0.0024766545,"about_ca_system_score_codex":0.0006391113,"about_ca_system_score_gemma":0.00030445156,"threshold_uncertainty_score":0.0049244165},"labels":[],"label_agreement":null},{"id":"W2030334551","doi":"10.1016/j.bbagen.2015.02.018","title":"Pin1: Intimate involvement with the regulatory protein kinase networks in the global phosphorylation landscape","year":2015,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - General Subjects","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Cancer Research Society","keywords":"Kinome; PIN1; Kinase; Phosphorylation; Biology; Protein phosphorylation; Autophagy-related protein 13; Cell biology; Protein kinase A; Computational biology; Biochemistry; Isomerase; Enzyme","score_opus":0.022980850837743847,"score_gpt":0.2829950764359822,"score_spread":0.26001422559823834,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2030334551","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003313885,0.99706167,0.00043349218,0.00033226065,0.00021683033,0.000005030228,0.00003583487,0.00001389647,0.0015696695],"genre_scores_gemma":[0.0022524877,0.9963308,0.00027001684,0.00014120202,0.00019168544,0.000007068017,0.0000589009,0.0000020213392,0.0007457828],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998765,0.000012183529,0.000012977739,0.000037885427,0.000037588343,0.00002291969],"domain_scores_gemma":[0.99987936,0.00004285246,0.000027492692,0.0000054384964,0.000025011595,0.000019752017],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041411948,0.0010919949,0.0011568927,0.0013844103,0.00029562548,0.0015303042,0.00094970607,0.0009873323,0.002132905],"category_scores_gemma":[0.00036276606,0.00038175346,0.00030274212,0.0018047601,0.00077140646,0.0016415329,0.0011718174,0.001901501,0.0014584602],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017304013,0.000040309526,0.0003860037,0.012906197,0.00012661058,0.00048454007,0.000088238776,0.0007922915,0.011082568,0.01555552,0.023919204,0.9344455],"study_design_scores_gemma":[0.000017008346,0.00005162225,0.0013809713,0.0010839787,0.00013549437,0.001557443,0.00007056268,0.0002070654,0.003731319,0.0056893625,0.9860407,0.00003461605],"about_ca_topic_score_codex":0.00058078876,"about_ca_topic_score_gemma":0.0010129715,"teacher_disagreement_score":0.002132905,"about_ca_system_score_codex":0.000806011,"about_ca_system_score_gemma":0.0007666514,"threshold_uncertainty_score":0.0071352124},"labels":[],"label_agreement":null},{"id":"W2031111639","doi":"10.1021/cg700689b","title":"Crystallization Characteristics of Calmodulin in Complex and Fused with Calcineurin Peptide","year":2007,"lang":"en","type":"article","venue":"Crystal Growth & Design","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Linker; Crystallization; Peptide; Chemistry; Crystallography; Calmodulin; Phosphatase; Serine; Stereochemistry; Biochemistry; Phosphorylation; Enzyme","score_opus":0.020556569786046905,"score_gpt":0.24291393833543978,"score_spread":0.22235736854939286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031111639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9896054,0.0012159074,0.0048627276,0.00024200432,0.000059146943,0.00009081907,0.0011118588,0.00013509876,0.0026771056],"genre_scores_gemma":[0.9730233,0.0011351566,0.013236289,0.00016614402,0.000035862493,0.00014197722,0.0055246274,0.00024527742,0.0064914497],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995454,0.000033852364,0.00005027093,0.00012351025,0.00018227643,0.00006458659],"domain_scores_gemma":[0.99957854,0.00010883566,0.000068568384,0.000050895957,0.00010582136,0.00008739988],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002308113,0.00038950806,0.00063626305,0.0004444566,0.00042290843,0.00062770053,0.0006458564,0.00055289373,0.0009639023],"category_scores_gemma":[0.0007561236,0.00028588157,0.00032595094,0.0008556736,0.00030226022,0.00029207594,0.00044777727,0.0008534909,0.0003288798],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000096592245,0.00008080403,0.00104752,0.0000430924,0.000017778024,0.00019750778,0.00014723615,0.00018221281,0.99680674,0.0001658146,0.00014124604,0.0010734304],"study_design_scores_gemma":[0.000053988264,0.00011085906,0.013761981,0.000020941121,0.000035591278,0.0004005864,0.00011307035,0.0068800617,0.9736285,0.00008890131,0.0048771617,0.000028265971],"about_ca_topic_score_codex":0.00699754,"about_ca_topic_score_gemma":0.010452082,"teacher_disagreement_score":0.00699754,"about_ca_system_score_codex":0.0009591312,"about_ca_system_score_gemma":0.0004906223,"threshold_uncertainty_score":0.013913572},"labels":[],"label_agreement":null},{"id":"W2031464903","doi":"10.1002/prot.22919","title":"Structures of parasitic CDPK domains point to a common mechanism of activation","year":2010,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Structural Genomics Consortium","funders":"Structural Genomics Consortium; Canadian Institutes of Health Research; Knut och Alice Wallenbergs Stiftelse; Stiftelsen för Strategisk Forskning; Ontario Innovation Trust; Wellcome Trust; Novartis Foundation; Ontario Genomics Institute; Merck; GlaxoSmithKline","keywords":"Mechanism (biology); Apicomplexa; Biology; Conformational change; Protein structure; Computational biology; Cell biology; Sequence (biology); Kinase; Biophysics; Plasmodium falciparum; Biochemistry; Physics; Immunology","score_opus":0.005729244152178639,"score_gpt":0.22686471104114725,"score_spread":0.22113546688896862,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031464903","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96379626,0.0022451486,0.025177635,0.000476883,0.000040945433,0.00005328184,0.0007560804,0.00022032643,0.0072334707],"genre_scores_gemma":[0.9917556,0.00044157854,0.006366859,0.000037407954,0.0000034499622,0.000013206769,0.00053097424,0.0000124918915,0.00083850004],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994826,0.0000067628484,0.000004688305,0.000015281152,0.0000135466025,0.000011430241],"domain_scores_gemma":[0.9998888,0.000018959401,0.000034178283,0.000019909816,0.000017737464,0.000020430267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009941118,0.0002487205,0.0002012719,0.00021441068,0.00034425437,0.00043504732,0.00022161641,0.0003630726,0.0014098181],"category_scores_gemma":[0.00028565954,0.00013742276,0.00025653394,0.00020932611,0.0004564275,0.00051818835,0.0002710652,0.0006674487,0.0003701695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042651282,0.00002962023,0.0039951717,0.00033448238,0.000038714716,0.0012847364,0.00040147264,0.0029204218,0.96983016,0.009893025,0.00055758574,0.010288076],"study_design_scores_gemma":[0.00014631331,0.00048332618,0.06499128,0.00007065701,0.0001290035,0.010305012,0.00075795816,0.026834473,0.8300919,0.015631394,0.050448112,0.00011055732],"about_ca_topic_score_codex":0.00062302453,"about_ca_topic_score_gemma":0.0006504621,"teacher_disagreement_score":0.0014098181,"about_ca_system_score_codex":0.00045278625,"about_ca_system_score_gemma":0.0002794935,"threshold_uncertainty_score":0.0047163367},"labels":[],"label_agreement":null},{"id":"W2031635095","doi":"10.1002/jcp.21134","title":"The participation of the Na<sup>+</sup>–Ca<sup>2+</sup> exchanger in primary cardiac myofibroblast migration, contraction, and proliferation","year":2007,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Hospital Research Foundation","keywords":"Myofibroblast; Motility; Myosin; RHOA; Cell biology; Myocyte; Contraction (grammar); Downregulation and upregulation; Chemistry; Biology; Internal medicine; Endocrinology; Medicine; Signal transduction; Biochemistry; Fibrosis","score_opus":0.007414312666150672,"score_gpt":0.23123147509775266,"score_spread":0.223817162431602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2031635095","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99234515,0.0041461266,0.0017898036,0.00015929426,0.000025834184,0.000035073594,0.00025891964,0.000037768757,0.0012019742],"genre_scores_gemma":[0.99339277,0.0017866603,0.0013981346,0.00007381479,0.0000237878,0.00007611885,0.0005906441,0.000012227627,0.0026457484],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998833,0.000015580432,0.000013640497,0.00002299755,0.000031356467,0.000033150787],"domain_scores_gemma":[0.9999213,0.000019058767,0.000016338774,0.000009139952,0.00001145064,0.000022644157],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021971422,0.00021632593,0.00024168218,0.00013036541,0.00018892477,0.00030443678,0.00014127805,0.0002445814,0.0009338996],"category_scores_gemma":[0.00007835961,0.0001378748,0.00021350429,0.000080389174,0.00016257433,0.0002853076,0.00012921641,0.00034558316,0.0003137522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012148656,0.000011306888,0.00024412923,0.000025957414,0.0000016662144,0.000035869565,0.000010225176,0.0000103976045,0.99896693,0.000031131905,0.000015955764,0.0005249543],"study_design_scores_gemma":[0.00002591936,0.0003181768,0.03209872,0.0000074971654,0.00002188081,0.00034419048,0.00006358859,0.00064030656,0.964319,0.00005880966,0.0020976681,0.000004438177],"about_ca_topic_score_codex":0.00045865073,"about_ca_topic_score_gemma":0.00082702446,"teacher_disagreement_score":0.0009338996,"about_ca_system_score_codex":0.00018973026,"about_ca_system_score_gemma":0.00019767182,"threshold_uncertainty_score":0.0031241775},"labels":[],"label_agreement":null},{"id":"W2032318771","doi":"10.1016/j.neuroscience.2011.12.010","title":"Role of calcineurin in inhibiting disadvantageous associations","year":2012,"lang":"en","type":"article","venue":"Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Calcineurin; Perseveration; Neuroscience; Extinction (optical mineralogy); Psychology; Memory consolidation; Morris water navigation task; Hippocampus; Biology; Cognition; Medicine; Internal medicine; Transplantation","score_opus":0.015021271480544903,"score_gpt":0.2844995921960835,"score_spread":0.2694783207155386,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2032318771","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9698518,0.010143342,0.008289942,0.001854345,0.00023465049,0.000054102515,0.00016796989,0.00033891833,0.009064858],"genre_scores_gemma":[0.9939102,0.0018859119,0.0027393932,0.00014200356,0.00004684478,0.0000168646,0.000039570165,0.000030501144,0.0011889125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997298,0.000054132124,0.000022255475,0.00004994157,0.00007711296,0.00006669117],"domain_scores_gemma":[0.9992957,0.00017283412,0.0001240199,0.00010233727,0.00007013738,0.00023487354],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00055142335,0.00039164413,0.0004092016,0.00061879394,0.0005762123,0.001226,0.0007962901,0.0008026004,0.0017702517],"category_scores_gemma":[0.001114063,0.00018078729,0.0002358813,0.00027640763,0.00109857,0.00056103634,0.00063147116,0.0011050239,0.00021864717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008580714,0.00020208553,0.0021351187,0.00015580258,0.00009226456,0.00056267093,0.00012775676,0.0007350913,0.9641483,0.012280141,0.00036152467,0.01834112],"study_design_scores_gemma":[0.00031889044,0.0009780079,0.016933618,0.000058917223,0.00021440572,0.0024181125,0.00023653713,0.008902976,0.9388552,0.014471463,0.016566902,0.000045012657],"about_ca_topic_score_codex":0.0012248391,"about_ca_topic_score_gemma":0.0024971636,"teacher_disagreement_score":0.0017702517,"about_ca_system_score_codex":0.0006945831,"about_ca_system_score_gemma":0.0008333299,"threshold_uncertainty_score":0.005922079},"labels":[],"label_agreement":null},{"id":"W2033489887","doi":"10.2174/1570161112666140226123139","title":"Ca&lt;sup&gt;2+&lt;/sup&gt;/Calmodulin-Dependent Protein Kinase- II in Vasoactive Peptide- Induced Responses and Vascular Biology","year":2014,"lang":"en","type":"review","venue":"Current Vascular Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Espace pour la vie","funders":"Canadian Institutes of Health Research","keywords":"Vasoactive; Calmodulin; Vasoactive intestinal peptide; Protein kinase A; Peptide; Cell biology; Endocrinology; Molecular biology; Kinase; Internal medicine; Chemistry; Biology; Medicine; Biochemistry; Calcium; Neuropeptide; Receptor","score_opus":0.041358282141209415,"score_gpt":0.3554352340151425,"score_spread":0.3140769518739331,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033489887","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00023986108,0.99625397,0.000325824,0.00023436281,0.0002949894,0.000009459379,0.000026277783,0.000020637,0.002594572],"genre_scores_gemma":[0.0010930658,0.9962127,0.0003758516,0.00012954333,0.00017252944,0.000009761576,0.00004620398,0.0000031214452,0.001957217],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99991286,0.000010201335,0.000012743537,0.000018029874,0.000034828412,0.000011369326],"domain_scores_gemma":[0.9999149,0.000024743535,0.00001413479,0.0000036644171,0.000026502785,0.000016006097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022819206,0.0006821914,0.0008318623,0.0016164775,0.00026993765,0.0007496218,0.0006378824,0.00074718264,0.005008941],"category_scores_gemma":[0.00021442988,0.0002258154,0.00032303558,0.0019167034,0.00035818625,0.0010389438,0.00057279906,0.0013844016,0.0047779786],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000599642,0.00008906047,0.00012809563,0.013857821,0.000054258766,0.00020217356,0.0000504683,0.00027971162,0.00853851,0.0039691,0.024405755,0.9483651],"study_design_scores_gemma":[0.000011585443,0.000064599124,0.0007797498,0.0013728688,0.000053066284,0.0009787489,0.00003386933,0.00008088587,0.0011249458,0.0016378608,0.99384934,0.000012538168],"about_ca_topic_score_codex":0.0006453939,"about_ca_topic_score_gemma":0.0011306356,"teacher_disagreement_score":0.005008941,"about_ca_system_score_codex":0.00044879148,"about_ca_system_score_gemma":0.00079413154,"threshold_uncertainty_score":0.016756535},"labels":[],"label_agreement":null},{"id":"W2033606638","doi":"10.1016/j.neuron.2009.05.007","title":"Neural Activity Regulates Synaptic Properties and Dendritic Structure In Vivo through Calcineurin/NFAT Signaling","year":2009,"lang":"en","type":"article","venue":"Neuron","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":93,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"NFAT; Xenopus; Calcineurin; Cell biology; Biology; Transcription factor; Phosphatase; Neuroscience; Phosphorylation; Biochemistry; Transplantation; Internal medicine","score_opus":0.019572010010689592,"score_gpt":0.2413975069720346,"score_spread":0.22182549696134501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033606638","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99300367,0.0014961859,0.0030705582,0.00023249982,0.000046974743,0.000008772887,0.0002242147,0.000062539846,0.0018545467],"genre_scores_gemma":[0.9952048,0.00079016533,0.0015268392,0.000044012006,0.000016156346,0.00001758164,0.00024716428,0.000062553554,0.0020906946],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996903,0.000034728037,0.000025828489,0.000069177855,0.000108642074,0.0000712556],"domain_scores_gemma":[0.9995426,0.000078161334,0.00013009961,0.0000668525,0.00006553196,0.00011674929],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034455198,0.00032735296,0.0003691604,0.0005691455,0.00057056744,0.0013095782,0.00066961715,0.0005500485,0.0011194343],"category_scores_gemma":[0.00053145847,0.00031385364,0.00038249642,0.0004432552,0.0007960432,0.0013121233,0.0005612955,0.0011588074,0.00030604607],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019695351,0.00002624652,0.00050818454,0.000016894794,0.00000996617,0.000043250835,0.000031727566,0.00006363151,0.9975458,0.0003628423,0.000032758562,0.0011616829],"study_design_scores_gemma":[0.00004973072,0.000117858566,0.045923375,0.000018121125,0.00004520772,0.00034822736,0.00013349079,0.0031715475,0.9484024,0.0008216658,0.00095167075,0.000016652017],"about_ca_topic_score_codex":0.0024234266,"about_ca_topic_score_gemma":0.0056124334,"teacher_disagreement_score":0.0024234266,"about_ca_system_score_codex":0.0013713692,"about_ca_system_score_gemma":0.00034514477,"threshold_uncertainty_score":0.009950042},"labels":[],"label_agreement":null},{"id":"W2033845358","doi":"10.1016/j.brainres.2011.08.050","title":"Tropisetron upregulates cannabinoid CB1 receptors in cerebellar granule cells: Possible involvement of calcineurin","year":2011,"lang":"en","type":"article","venue":"Brain Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Cannabinoid receptor; Neuroscience; Cannabinoid; Receptor; Cerebellum; Calcineurin; Chemistry; Granule (geology); Biology; Medicine; Internal medicine; Agonist; Biochemistry","score_opus":0.0647577592734605,"score_gpt":0.323392763228922,"score_spread":0.2586350039554615,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2033845358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944224,0.0017640075,0.00096733135,0.00021954862,0.00005676658,0.00002305846,0.00026881834,0.00009653826,0.0021815414],"genre_scores_gemma":[0.9946057,0.0009999558,0.0008512457,0.00009362971,0.000023940931,0.000032151343,0.00021410726,0.000028353337,0.003150847],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986064,0.000024521614,0.000010840922,0.000023813585,0.000028797023,0.000051282466],"domain_scores_gemma":[0.999848,0.0000532754,0.00002785396,0.00002200773,0.000016746797,0.000031966196],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001337855,0.00040209462,0.0004620976,0.0003604931,0.0002687133,0.00038877723,0.00026690046,0.0003724951,0.003541036],"category_scores_gemma":[0.00021961077,0.00019374189,0.00051280507,0.00020167993,0.00028414684,0.00044440114,0.00016469049,0.0005727665,0.0003789954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00055177964,0.000026938716,0.00014290088,0.000039301533,0.000007767441,0.00020692655,0.000025319956,0.000024951405,0.9976301,0.00012337943,0.000044909575,0.0011757447],"study_design_scores_gemma":[0.00006643358,0.00054633414,0.0048938734,0.0000072664247,0.000047595808,0.00044420248,0.00007110134,0.00022300698,0.9924183,0.00007145529,0.0012026993,0.000007828822],"about_ca_topic_score_codex":0.001544683,"about_ca_topic_score_gemma":0.0031946946,"teacher_disagreement_score":0.003541036,"about_ca_system_score_codex":0.0005972002,"about_ca_system_score_gemma":0.00032285636,"threshold_uncertainty_score":0.011845887},"labels":[],"label_agreement":null},{"id":"W2034267606","doi":"10.1186/1472-6750-8-5","title":"Generation of functional scFv intrabody to abate the expression of CD147 surface molecule of 293A cells","year":2008,"lang":"en","type":"article","venue":"BMC Biotechnology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"Canadian Institutes of Health Research; National Center for Genetic Engineering and Biotechnology; Commission on Higher Education; Thailand Research Fund","keywords":"Biology; Recombinant DNA; Antibody; Molecular biology; Monoclonal antibody; Flow cytometry; clone (Java method); Cell biology; Colocalization; Cell; Phage display; Gene; Biochemistry; Genetics","score_opus":0.04013471171782685,"score_gpt":0.24555077396201844,"score_spread":0.2054160622441916,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034267606","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9145772,0.0023364958,0.07430129,0.00037197932,0.00024921668,0.00037616782,0.0022419943,0.00042486924,0.005120781],"genre_scores_gemma":[0.94774765,0.0014064618,0.039373394,0.00025579275,0.00004763556,0.00032715785,0.0045631835,0.00012562536,0.0061531174],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997229,0.000029912699,0.000030424,0.000053847634,0.00011128489,0.00005164706],"domain_scores_gemma":[0.9998758,0.000020866271,0.000019396213,0.000022591057,0.00003766295,0.000023601913],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002838731,0.00033861707,0.00049789785,0.00029039278,0.00019322625,0.0003788737,0.00033191405,0.0005538775,0.0013403146],"category_scores_gemma":[0.00020353311,0.00016000634,0.00042847937,0.00026823953,0.00018931752,0.00020710223,0.0002638947,0.0011731694,0.0009617025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000030505067,0.00002683765,0.00013261959,0.000031049967,0.0000042441707,0.00004071186,0.000013960564,0.000047288144,0.9985273,0.00012813689,0.00006908908,0.0009482122],"study_design_scores_gemma":[0.00001686554,0.000087487555,0.0009663513,0.0000060917487,0.00001783185,0.00029553025,0.000013695944,0.0018890817,0.9917149,0.00004919181,0.004938585,0.0000042723036],"about_ca_topic_score_codex":0.0003083463,"about_ca_topic_score_gemma":0.0002674512,"teacher_disagreement_score":0.0013403146,"about_ca_system_score_codex":0.00036043473,"about_ca_system_score_gemma":0.00017963414,"threshold_uncertainty_score":0.0044837594},"labels":[],"label_agreement":null},{"id":"W2034425544","doi":"10.1002/jcb.22761","title":"Proanthocyanidins from the American Cranberry (<i>Vaccinium macrocarpon</i>) inhibit matrix metalloproteinase‐2 and matrix metalloproteinase‐9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways","year":2010,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"","keywords":"DU145; Cancer research; Prostate cancer; Matrix metalloproteinase; Cancer cell; Biology; Protein kinase B; Cancer; Signal transduction; Chemistry; Cell biology; LNCaP; Biochemistry","score_opus":0.00951204456604687,"score_gpt":0.25298383791340445,"score_spread":0.24347179334735758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2034425544","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923218,0.0052886354,0.001034851,0.000088408604,0.000026384532,0.000027394604,0.000124859,0.000034267232,0.0010534402],"genre_scores_gemma":[0.9936574,0.0028097855,0.0017664081,0.0000618504,0.000016628212,0.000019163248,0.00025816853,0.000008032647,0.0014025989],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999964,0.000006413047,0.0000026526172,0.000006414429,0.000009818846,0.0000108341765],"domain_scores_gemma":[0.99995863,0.000007642414,0.000014638515,0.0000033603305,0.000005291727,0.000010413596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000060750557,0.00027125442,0.00014732973,0.0001262028,0.00007655623,0.000114928764,0.000076934746,0.00013372059,0.00070218684],"category_scores_gemma":[0.000068567024,0.00007898447,0.0002546427,0.00008543249,0.000102586855,0.00010760178,0.00008735752,0.00032535268,0.000100678095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009687567,0.00004013339,0.000114887356,0.00004999127,0.000006177258,0.000022114356,0.000007639187,0.000021376627,0.9980465,0.000015871314,0.000023298528,0.001555082],"study_design_scores_gemma":[0.000035193098,0.0017782515,0.016251659,0.000010053379,0.000035652283,0.0003198187,0.000026216543,0.0002581808,0.97751075,0.000025817895,0.003744161,0.0000042458287],"about_ca_topic_score_codex":0.0007964407,"about_ca_topic_score_gemma":0.0011363287,"teacher_disagreement_score":0.0007964407,"about_ca_system_score_codex":0.00008529582,"about_ca_system_score_gemma":0.00010366919,"threshold_uncertainty_score":0.002349019},"labels":[],"label_agreement":null},{"id":"W2035012256","doi":"10.1523/jneurosci.3513-12.2013","title":"Regulator of Calcineurin 1 Modulates Expression of Innate Anxiety and Anxiogenic Responses to Selective Serotonin Reuptake Inhibitor Treatment","year":2013,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institute of Neurological Disorders and Stroke; York University","keywords":"CREB; Anxiogenic; Calcineurin; Anxiolytic; Serotonin reuptake inhibitor; Endocrinology; Internal medicine; Pharmacology; Neuroscience; Psychology; Antidepressant; Biology; Transcription factor; Medicine; Receptor; Hippocampus; Biochemistry; Transplantation","score_opus":0.016020904959033435,"score_gpt":0.2677767430328633,"score_spread":0.2517558380738299,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035012256","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957722,0.0024328076,0.0003865028,0.00011648017,0.000028437638,0.000028304818,0.00022151408,0.00005556076,0.00095813844],"genre_scores_gemma":[0.99666995,0.0010618104,0.00035263892,0.00007177408,0.000012307856,0.000038820926,0.00030514618,0.000008837767,0.0014787728],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998909,0.000011624488,0.000008216312,0.00002032593,0.00002755493,0.000041333504],"domain_scores_gemma":[0.9999002,0.000007737036,0.00004376675,0.000006596917,0.000012946573,0.000028650593],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009128702,0.00021434118,0.00032926537,0.00023617389,0.00012677474,0.0002629649,0.00016718055,0.00023116238,0.0011197446],"category_scores_gemma":[0.00014382432,0.000094394454,0.00022547848,0.00012511494,0.00023101187,0.00013814153,0.00009739139,0.00053581217,0.00013646299],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067148614,0.00011158973,0.0010745858,0.00007093136,0.000018889637,0.000073879644,0.00002644212,0.00006087952,0.9949221,0.00006839413,0.00010241759,0.0027983757],"study_design_scores_gemma":[0.0001570731,0.0016339569,0.12070254,0.000024903464,0.00014442099,0.0005515801,0.00011777398,0.0020831332,0.87029976,0.00014475966,0.004118963,0.000021182916],"about_ca_topic_score_codex":0.0009409591,"about_ca_topic_score_gemma":0.0021435258,"teacher_disagreement_score":0.0011197446,"about_ca_system_score_codex":0.0003393513,"about_ca_system_score_gemma":0.0002589799,"threshold_uncertainty_score":0.003745854},"labels":[],"label_agreement":null},{"id":"W2035493973","doi":"10.1016/j.neuroscience.2004.06.016","title":"Neuroimmunophilins: A novel drug therapy for the reversal of neurodegenerative disease?","year":2004,"lang":"en","type":"review","venue":"Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Neuroprotection; Medicine; Dopaminergic; Neurotrophin; Neurotrophic factors; Neuroscience; Pharmacology; Population; Clinical trial; Internal medicine; Bioinformatics; Receptor; Biology; Dopamine","score_opus":0.0747301604370545,"score_gpt":0.34533501623971113,"score_spread":0.27060485580265664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035493973","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00035248123,0.9944425,0.0007640103,0.0014451027,0.000888705,0.00000948941,0.00003597697,0.000029289853,0.00203245],"genre_scores_gemma":[0.0018889387,0.993131,0.00074988796,0.00082344905,0.00056810665,0.000021878905,0.00006488875,0.0000041884205,0.0027476205],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99987507,0.000021821983,0.000013453471,0.000024169527,0.000045175682,0.000020284073],"domain_scores_gemma":[0.9998248,0.00007230314,0.000020215464,0.0000072951398,0.00004488445,0.000030443067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007605655,0.0014699153,0.0019416626,0.0011097277,0.00040677993,0.0012379315,0.0013037726,0.0020198778,0.0035344635],"category_scores_gemma":[0.00044871596,0.00026994818,0.00040823262,0.0013007462,0.0009243085,0.0016617135,0.0005091046,0.00325517,0.003207669],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040070794,0.00017440903,0.00016497402,0.0035747937,0.00009719237,0.000592543,0.000049390117,0.0004620954,0.0068788487,0.009023388,0.075009644,0.903572],"study_design_scores_gemma":[0.0001381262,0.00020489306,0.0004607874,0.00063016545,0.000092964736,0.0017115189,0.000049777384,0.00015789362,0.0019785846,0.0039524445,0.990598,0.000024784626],"about_ca_topic_score_codex":0.0011335183,"about_ca_topic_score_gemma":0.0028497253,"teacher_disagreement_score":0.0035344635,"about_ca_system_score_codex":0.0007241547,"about_ca_system_score_gemma":0.0007597513,"threshold_uncertainty_score":0.011823952},"labels":[],"label_agreement":null},{"id":"W2035542471","doi":"10.1021/pr800174k","title":"Comparative Proteomic Analysis of Matched Primary and Metastatic Melanoma Cell Lines","year":2008,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"National Institute of Biomedical Imaging and Bioengineering; National Cancer Institute","keywords":"Melanoma; Proteomics; Cell culture; Metastatic melanoma; Two-dimensional gel electrophoresis; Cancer research; Proteome; Metastasis; Biology; Pathology; Medicine; Cancer; Bioinformatics; Biochemistry; Genetics; Gene","score_opus":0.09580787983069965,"score_gpt":0.37474266378489945,"score_spread":0.2789347839541998,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035542471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9841353,0.0024291025,0.006056256,0.00008526488,0.00007528202,0.00012523412,0.003654003,0.00012855485,0.0033109928],"genre_scores_gemma":[0.9560384,0.0042007654,0.017559508,0.00016413504,0.000056052602,0.00025334582,0.014715905,0.00009067382,0.0069210352],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998504,0.000015932452,0.00001333248,0.000030110952,0.00006488756,0.00002538967],"domain_scores_gemma":[0.99988365,0.000024905212,0.000010400449,0.000014889945,0.00004196725,0.000024259287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017578462,0.00030729244,0.00036586597,0.0005856789,0.00027639655,0.00028468456,0.00015413555,0.0002099057,0.0016943484],"category_scores_gemma":[0.00024612958,0.00009597273,0.00035491952,0.00039073982,0.00011524483,0.00012971653,0.00016847419,0.0002792136,0.00069412414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079889316,0.000016242484,0.00029550047,0.00003777456,0.000006321528,0.00012968354,0.000021803335,0.000021452228,0.9986015,0.00003026949,0.00004190584,0.0007177214],"study_design_scores_gemma":[0.00004241516,0.0011185585,0.06289254,0.000019866506,0.00013513,0.0042137997,0.00026770853,0.0014408245,0.9199508,0.00012950551,0.00976915,0.00001970247],"about_ca_topic_score_codex":0.0014006196,"about_ca_topic_score_gemma":0.0021578213,"teacher_disagreement_score":0.0016943484,"about_ca_system_score_codex":0.00020370705,"about_ca_system_score_gemma":0.00018324424,"threshold_uncertainty_score":0.0056681633},"labels":[],"label_agreement":null},{"id":"W2035968568","doi":"10.1152/ajpheart.00386.2008","title":"iNOS in cardiac myocytes plays a critical role in death in a murine model of hypertrophy induced by calcineurin","year":2008,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta","funders":"","keywords":"Calcineurin; Internal medicine; Endocrinology; Nitric oxide synthase; Myocyte; Nitric oxide; Apoptosis; Muscle hypertrophy; NFAT; Fibrosis; Medicine; Biology; Chemistry; Transplantation; Biochemistry","score_opus":0.01556024544849111,"score_gpt":0.2519883012628259,"score_spread":0.2364280558143348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2035968568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99142706,0.0017479826,0.004355939,0.00020086745,0.00007973665,0.00008272802,0.00015809978,0.00016098341,0.0017865257],"genre_scores_gemma":[0.9899455,0.0011570498,0.0037094231,0.0001299738,0.000036168985,0.00016143307,0.00031451037,0.0000334871,0.0045125275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997433,0.00005120486,0.000025550267,0.000055815857,0.000080625105,0.000043466738],"domain_scores_gemma":[0.9997539,0.000021134158,0.00007955907,0.000025979944,0.000022150814,0.00009724048],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034127015,0.0007236997,0.00031384797,0.00037611084,0.00024740314,0.00027527072,0.0002945404,0.00048435203,0.0014810397],"category_scores_gemma":[0.00014751304,0.00025910686,0.0002486477,0.00015351291,0.00049938174,0.00029527873,0.00029999934,0.0010815931,0.00031514533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004805613,0.00014879947,0.0003643615,0.000047544254,0.000006449854,0.00016826045,0.000021317723,0.00007510346,0.99703205,0.00018914747,0.00005070064,0.0014156523],"study_design_scores_gemma":[0.00032327688,0.0054114764,0.013203174,0.00007182913,0.00010278436,0.0020916641,0.0000945387,0.0038382374,0.9709552,0.0004964043,0.003396563,0.000014913781],"about_ca_topic_score_codex":0.00023231818,"about_ca_topic_score_gemma":0.00044492885,"teacher_disagreement_score":0.0014810397,"about_ca_system_score_codex":0.00025939135,"about_ca_system_score_gemma":0.00026582598,"threshold_uncertainty_score":0.004954517},"labels":[],"label_agreement":null},{"id":"W2036185981","doi":"10.1073/pnas.0813296106","title":"Requirement for balanced Ca/NFAT signaling in hematopoietic and embryonic development","year":2009,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Leukemia and Lymphoma Society; Canadian Institutes of Health Research; Deutsche Krebshilfe; National Cancer Institute; National Institutes of Health; Cancer Research Institute","keywords":"NFAT; Calcineurin; Biology; Cell biology; Transcription factor; Embryonic stem cell; Phosphatase; Signal transduction; Phosphorylation; Molecular biology; Transplantation; Genetics; Internal medicine","score_opus":0.03619291705222411,"score_gpt":0.31062750371887476,"score_spread":0.27443458666665066,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2036185981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9804848,0.004414759,0.0101013845,0.00029910493,0.000047471545,0.00006608677,0.0008892308,0.00038537988,0.003311889],"genre_scores_gemma":[0.9894952,0.0009879265,0.006067543,0.00008638632,0.000021220167,0.000078792196,0.0008370091,0.00010012506,0.0023259013],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994894,0.000044858567,0.00005322674,0.00017698426,0.00013042027,0.00010493715],"domain_scores_gemma":[0.9994307,0.00006492989,0.0002083157,0.000079425416,0.00004456076,0.00017204945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023528675,0.00048086824,0.0002787904,0.00039406103,0.00025753627,0.0005230383,0.00067195186,0.00056623475,0.0014533458],"category_scores_gemma":[0.00028009238,0.00028848374,0.0002405362,0.00019340745,0.00056846265,0.00048211665,0.000512306,0.0007421969,0.00042219527],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006218459,0.00001756806,0.00030123157,0.00002147743,0.0000036819106,0.00007109957,0.000008602068,0.000050387964,0.9984835,0.00027269786,0.00001835962,0.0006892866],"study_design_scores_gemma":[0.000035351302,0.00016878358,0.011004597,0.000020458046,0.000029674677,0.0010682028,0.000047252157,0.0009208708,0.9787002,0.0003596193,0.00762869,0.000016349964],"about_ca_topic_score_codex":0.0010316579,"about_ca_topic_score_gemma":0.0017929127,"teacher_disagreement_score":0.0014533458,"about_ca_system_score_codex":0.00061582925,"about_ca_system_score_gemma":0.0006379554,"threshold_uncertainty_score":0.0048618913},"labels":[],"label_agreement":null},{"id":"W2038043012","doi":"10.1074/jbc.m110.177519","title":"Regulator of Calcineurin 1 (RCAN1) Facilitates Neuronal Apoptosis through Caspase-3 Activation","year":2011,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Michael Smith Health Research BC","keywords":"Neurodegeneration; Neuropathology; Biology; Neuroscience; Cell biology; Senile plaques; Neurotoxicity; Alzheimer's disease; Medicine; Internal medicine; Disease","score_opus":0.05614378207237129,"score_gpt":0.2635291405940673,"score_spread":0.20738535852169598,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038043012","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9894504,0.0046307202,0.0032295377,0.00022344179,0.00006067285,0.000024973739,0.00034126328,0.00011907058,0.001920009],"genre_scores_gemma":[0.99309534,0.0017819791,0.0019803948,0.000054084707,0.000014326949,0.000021891308,0.0003655104,0.000010880913,0.0026755433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991727,0.0000147192695,0.000005987562,0.00002621742,0.00002195391,0.000013891194],"domain_scores_gemma":[0.99991536,0.00001593683,0.000029029949,0.00000844359,0.000011507312,0.000019578461],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008616368,0.0004700701,0.00013209412,0.00023818761,0.00017973265,0.0002674104,0.00018707218,0.0002276618,0.0014431943],"category_scores_gemma":[0.00013043529,0.00007993434,0.00019337352,0.00011841882,0.00021121064,0.00018180911,0.0001941863,0.00037926016,0.00027063262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004933934,0.000011726309,0.00021753869,0.000031274514,0.0000035323685,0.00008550363,0.0000092063065,0.000035352452,0.9984861,0.00014256145,0.000030924923,0.00089678634],"study_design_scores_gemma":[0.0000204589,0.00010746893,0.0093859155,0.000010402958,0.000016635297,0.00064929784,0.000028600756,0.0009404911,0.98478645,0.00020819811,0.0038407696,0.0000053488693],"about_ca_topic_score_codex":0.0005869027,"about_ca_topic_score_gemma":0.0009474534,"teacher_disagreement_score":0.0014431943,"about_ca_system_score_codex":0.00040028643,"about_ca_system_score_gemma":0.00020186613,"threshold_uncertainty_score":0.004828036},"labels":[],"label_agreement":null},{"id":"W2039643947","doi":"10.1158/1538-7445.am2013-824","title":"Abstract 824: Regulation of PAR-4 activity in chemoresistant ovarian cancer cells: A major role for the cleaved fragment in the control of apoptosis.","year":2013,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Trois-Rivières; Innovation and Economic Development Trois Rivières","funders":"","keywords":"Cisplatin; Apoptosis; Ovarian cancer; Cancer research; In vivo; Cancer cell; Chemistry; In vitro; Cancer; Prostate cancer; Cell culture; Molecular biology; Biology; Chemotherapy; Medicine; Internal medicine; Biochemistry; Genetics","score_opus":0.032790366644780876,"score_gpt":0.3383811690952405,"score_spread":0.30559080245045966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039643947","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990308,0.002284505,0.0035584029,0.00020178671,0.000036317226,0.000073984826,0.0013950396,0.000063919986,0.0020780056],"genre_scores_gemma":[0.9882734,0.0010157998,0.0033088506,0.00011100778,0.000017176513,0.00010953739,0.0025263953,0.000022726836,0.0046151527],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984896,0.00002416037,0.000016965258,0.000032899832,0.000045208337,0.00003187223],"domain_scores_gemma":[0.9999237,0.000016625516,0.00002278445,0.000012074839,0.000012239961,0.000012492769],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009076769,0.00028191227,0.0002476299,0.0002027937,0.00012497423,0.00026945167,0.00023287504,0.000285632,0.002677012],"category_scores_gemma":[0.000118632095,0.000123946,0.0002757551,0.00022296309,0.00018318187,0.0002784448,0.00014570521,0.00063669437,0.00059793686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007401826,0.000019492,0.00013252486,0.000024616123,0.000003675791,0.00003378622,0.000006331917,0.000021572467,0.99897087,0.00006215102,0.00003298336,0.0006179319],"study_design_scores_gemma":[0.000021134223,0.00020745434,0.005738132,0.0000022938805,0.00001147935,0.00030907008,0.000014615938,0.0004158705,0.9916524,0.000032505646,0.0015923909,0.0000025858421],"about_ca_topic_score_codex":0.000575064,"about_ca_topic_score_gemma":0.00036091177,"teacher_disagreement_score":0.002677012,"about_ca_system_score_codex":0.00030447452,"about_ca_system_score_gemma":0.00015767754,"threshold_uncertainty_score":0.008955538},"labels":[],"label_agreement":null},{"id":"W2039824686","doi":"10.1042/bsr20140149","title":"The proline-rich region of 18.5 kDa myelin basic protein binds to the SH3-domain of Fyn tyrosine kinase with the aid of an upstream segment to form a dynamic complex<i>in vitro</i>","year":2014,"lang":"en","type":"article","venue":"Bioscience Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Multiple Sclerosis Society; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Multiple Sclerosis Society of Canada","keywords":"SH3 domain; FYN; Myelin basic protein; Tyrosine kinase; Kinase; Proto-oncogene tyrosine-protein kinase Src; Chemistry; SH2 domain; Protein kinase domain; Biology; Biochemistry; Biophysics; Signal transduction; Myelin","score_opus":0.009915462824366734,"score_gpt":0.24608951045562008,"score_spread":0.23617404763125335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039824686","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99262273,0.00066421455,0.005882401,0.000033885586,0.0000072171206,0.0000127339645,0.00014595728,0.00004004038,0.00059085904],"genre_scores_gemma":[0.98927665,0.00049743353,0.0076612937,0.00003406013,0.000008260856,0.000016732787,0.00082100095,0.000017344608,0.0016672371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990726,0.000013240269,0.0000048860265,0.000024029923,0.000030030988,0.000020594143],"domain_scores_gemma":[0.9999298,0.000012625494,0.000027482936,0.000007630848,0.000006715883,0.000015726248],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010727528,0.00031060312,0.00016682879,0.00009137499,0.00014227534,0.00020583639,0.00018014408,0.0001726359,0.00078765204],"category_scores_gemma":[0.00009354417,0.00010018086,0.00023226059,0.00011323017,0.00014563007,0.00013239651,0.00019877295,0.00033132947,0.000389693],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019959964,0.0000071784234,0.00019075736,0.000010245352,0.0000020993618,0.00002405036,0.000008923678,0.00001807449,0.99933285,0.00003692119,0.000009179119,0.00033966504],"study_design_scores_gemma":[0.000003953895,0.00011483536,0.005919195,0.0000030849344,0.0000059550266,0.00037688384,0.000020941034,0.0006654494,0.9905426,0.000035747817,0.0023085612,0.000002852287],"about_ca_topic_score_codex":0.00092783576,"about_ca_topic_score_gemma":0.00096777495,"teacher_disagreement_score":0.00092783576,"about_ca_system_score_codex":0.00025115567,"about_ca_system_score_gemma":0.00014061682,"threshold_uncertainty_score":0.0026349425},"labels":[],"label_agreement":null},{"id":"W2039967958","doi":"10.1021/bi800964q","title":"The Dual Histidine Motif in the Active Site of Pin1 Has a Structural Rather than Catalytic Role","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Schulich School of Medicine and Dentistry; Schulich School of Medicine and Dentistry, Western University","keywords":"Motif (music); Histidine; Structural motif; Chemistry; PIN1; Active site; Dual role; Catalysis; Biochemistry; Combinatorial chemistry; Isomerase; Enzyme; Philosophy","score_opus":0.013510642065952129,"score_gpt":0.22896278890091698,"score_spread":0.21545214683496486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2039967958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9874113,0.0010388783,0.008562724,0.00028100144,0.00010237591,0.000025504723,0.00028322102,0.00010535986,0.0021895822],"genre_scores_gemma":[0.9958866,0.00013420313,0.002474983,0.00008652741,0.000010952301,0.000007036195,0.00022450888,0.000010059966,0.0011651495],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999229,0.0000074477325,0.0000053220656,0.00002928158,0.00002085468,0.000014123719],"domain_scores_gemma":[0.9999175,0.000011979998,0.000023945273,0.000009359155,0.000007126034,0.00003006462],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000087056804,0.0003658993,0.00030248825,0.000085042826,0.00020081757,0.00036124876,0.00037034776,0.0006218568,0.0030334613],"category_scores_gemma":[0.00010992488,0.0001404911,0.0003382834,0.00007618395,0.00032574811,0.00033926815,0.00033687972,0.0005722474,0.0012526631],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022829807,0.000028048395,0.00071275316,0.00008710862,0.000008964344,0.00038259616,0.000014661514,0.00009733604,0.99534434,0.00048599494,0.00007556705,0.0025342794],"study_design_scores_gemma":[0.000055606994,0.0002597398,0.012115618,0.000015132243,0.000023835302,0.0022185706,0.00005696358,0.0020639584,0.97824246,0.00029745512,0.004631745,0.000018927827],"about_ca_topic_score_codex":0.00025549193,"about_ca_topic_score_gemma":0.00024792875,"teacher_disagreement_score":0.0030334613,"about_ca_system_score_codex":0.0002352031,"about_ca_system_score_gemma":0.00015491765,"threshold_uncertainty_score":0.010147929},"labels":[],"label_agreement":null},{"id":"W2040434984","doi":"10.1371/journal.pone.0115258","title":"Liganded Peroxisome Proliferator-Activated Receptors (PPARs) Preserve Nuclear Histone Deacetylase 5 Levels in Endothelin-Treated Sprague-Dawley Rat Cardiac Myocytes","year":2014,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Histone deacetylase 5; Histone deacetylase; Diacylglycerol kinase; Biology; Cell biology; Protein kinase C; Phosphorylation; Signal transduction; HDAC4; Mef2; Nuclear export signal; Histone; Transcription factor; Biochemistry; Cell nucleus; Cytoplasm; Enhancer","score_opus":0.028916202770932615,"score_gpt":0.23824707861178196,"score_spread":0.20933087584084933,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2040434984","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963568,0.00065560004,0.0016797284,0.00009084657,0.00005883568,0.000015226092,0.0003540269,0.00006493886,0.0007240896],"genre_scores_gemma":[0.99184084,0.00069480925,0.0020099154,0.00010049563,0.000017114431,0.00003566508,0.00069022254,0.000035167475,0.004575703],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985695,0.000014202449,0.000022056633,0.000038772407,0.000030610103,0.00003735023],"domain_scores_gemma":[0.9998456,0.000017833396,0.000037505863,0.00002426091,0.000017792388,0.000057007408],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015637446,0.00031465327,0.00023707177,0.00017463624,0.00013632253,0.0001721592,0.00018610116,0.00016064857,0.0013179347],"category_scores_gemma":[0.00009321693,0.00017734544,0.0002994413,0.0001188674,0.00022381166,0.0001576069,0.00017635728,0.00058558234,0.0003022726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018811703,0.000023452245,0.00010549813,0.000009486486,0.0000034194172,0.000015808106,0.000010211639,0.000013956925,0.99922895,0.000021677331,0.00001094202,0.00036845528],"study_design_scores_gemma":[0.000028825316,0.0005445459,0.0039525535,0.000003244237,0.000015565163,0.000057129997,0.000037461657,0.00018429763,0.9944418,0.000022196991,0.0007088792,0.0000036319318],"about_ca_topic_score_codex":0.00090130244,"about_ca_topic_score_gemma":0.0019631558,"teacher_disagreement_score":0.0013179347,"about_ca_system_score_codex":0.0002180349,"about_ca_system_score_gemma":0.00023607051,"threshold_uncertainty_score":0.0044089556},"labels":[],"label_agreement":null},{"id":"W2041766744","doi":"10.1016/j.regpep.2004.12.025","title":"Determinants of inducible brain natriuretic peptide promoter activity","year":2005,"lang":"en","type":"review","venue":"Regulatory Peptides","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Brain natriuretic peptide; NPR1; NPR2; Natriuretic peptide; Peptide; Internal medicine; Chemistry; Medicine; Biochemistry","score_opus":0.042192600980725484,"score_gpt":0.3392112717487271,"score_spread":0.29701867076800165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2041766744","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021876795,0.98721397,0.0040931753,0.0005937048,0.0007096127,0.000016424763,0.00011613244,0.00006707265,0.0050020902],"genre_scores_gemma":[0.00841217,0.9832396,0.002677965,0.00038500462,0.00047978546,0.000035132947,0.00022637108,0.000010218267,0.004533739],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998468,0.000017211376,0.000018318166,0.000044478158,0.0000530477,0.000020086458],"domain_scores_gemma":[0.99976784,0.00009451772,0.000036898775,0.000010547426,0.00006017689,0.00002995024],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005766005,0.0011248909,0.0012528176,0.00091391156,0.00019236041,0.0011045787,0.0009428806,0.00085456873,0.0016900274],"category_scores_gemma":[0.00050561776,0.00034114067,0.00022970658,0.00090325275,0.0008496961,0.00084244285,0.00048177212,0.001760675,0.0014977276],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019953602,0.00009730751,0.00058143184,0.0040922575,0.000048106485,0.00079176604,0.00007151124,0.0010203124,0.0678526,0.011617288,0.016396146,0.8972318],"study_design_scores_gemma":[0.00006867592,0.00012254548,0.003310557,0.0010564065,0.0001384688,0.0029258304,0.00014280174,0.0005093844,0.034714032,0.0064934404,0.95046324,0.00005461674],"about_ca_topic_score_codex":0.0006567104,"about_ca_topic_score_gemma":0.0008579768,"teacher_disagreement_score":0.0016900274,"about_ca_system_score_codex":0.0007164174,"about_ca_system_score_gemma":0.0007244732,"threshold_uncertainty_score":0.005653739},"labels":[],"label_agreement":null},{"id":"W2042082983","doi":"10.1074/jbc.m114.628438","title":"IgLON Cell Adhesion Molecules Are Shed from the Cell Surface of Cortical Neurons to Promote Neuronal Growth","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":104,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Neurite; Ectodomain; Cell biology; Disintegrin; Synaptogenesis; Metalloproteinase; Matrix metalloproteinase; Extracellular matrix; Biology; Cell adhesion molecule; Axon guidance; Cell adhesion; Axon; Chemistry; Cell; Receptor; Biochemistry; In vitro","score_opus":0.014726746605909996,"score_gpt":0.2270627764577942,"score_spread":0.2123360298518842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042082983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992743,0.0023529571,0.003391056,0.000061144085,0.0000187685,0.000018151992,0.00041827175,0.000052103656,0.00094439037],"genre_scores_gemma":[0.99113584,0.0020923184,0.0032954686,0.00007072392,0.00001349881,0.000029478237,0.0007625745,0.000017801529,0.0025823037],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993,0.000006543771,0.0000051027478,0.000014540299,0.000023274964,0.000020470232],"domain_scores_gemma":[0.99992025,0.000008247422,0.000023375482,0.000008516594,0.00001560982,0.000024016166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007721728,0.00034716175,0.00022524812,0.00022308729,0.00011833292,0.00027328386,0.00014346643,0.00016430182,0.0005447164],"category_scores_gemma":[0.0001250498,0.00010897212,0.00017712169,0.00013624612,0.0001084631,0.00016142016,0.00018581393,0.00031028315,0.00027744047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000019507308,0.0000025287643,0.00016116185,0.000012159908,0.0000022056968,0.000056054127,0.0000065405384,0.000009942978,0.99906343,0.000018988518,0.0000139822005,0.0006334059],"study_design_scores_gemma":[0.000007322377,0.00012419693,0.027073732,0.000009555518,0.000020244084,0.0008182284,0.000062379135,0.00065786013,0.9680544,0.00011180332,0.0030549911,0.000005299627],"about_ca_topic_score_codex":0.000647701,"about_ca_topic_score_gemma":0.0009588786,"teacher_disagreement_score":0.000647701,"about_ca_system_score_codex":0.00030011692,"about_ca_system_score_gemma":0.00021886658,"threshold_uncertainty_score":0.0021775365},"labels":[],"label_agreement":null},{"id":"W2042113382","doi":"10.1242/jcs.110262","title":"Intrinsic directionality of migrating vascular smooth muscle cells is regulated by NAD+ biosynthesis","year":2012,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Western University; Robarts Clinical Trials","funders":"Canadian Institutes of Health Research","keywords":"Lamellipodium; Cell biology; Biology; Motility; Pseudopodia; Nicotinamide phosphoribosyltransferase; Cell migration; NAD+ kinase; Filopodia; Cell; Biochemistry; Actin","score_opus":0.008005195257172868,"score_gpt":0.23047652968858962,"score_spread":0.22247133443141676,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042113382","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948053,0.000720578,0.0033847862,0.000043443157,0.000010537606,0.000005683143,0.000115178744,0.00005045029,0.00086407206],"genre_scores_gemma":[0.9974948,0.00027182163,0.0014435586,0.000006977032,0.0000026067885,0.00000468624,0.000092277805,0.000007643801,0.0006756376],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995005,0.000007997436,0.0000045359034,0.00001630035,0.000011154199,0.00000991377],"domain_scores_gemma":[0.99993885,0.000008565919,0.000016454087,0.000007536636,0.000013483745,0.0000151519425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000088846864,0.00013745579,0.00009352188,0.000088403605,0.00011099715,0.00031509486,0.00008180098,0.00009184234,0.00036587767],"category_scores_gemma":[0.0000998504,0.00009651375,0.000075045406,0.00005717996,0.00010787866,0.000101067264,0.000111899615,0.0001517383,0.00015211018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053799922,0.000002651109,0.0005379513,0.00000985279,0.0000010430272,0.000013489623,0.000007373278,0.000028370527,0.99815625,0.00006700484,0.00000941029,0.0011127921],"study_design_scores_gemma":[0.0000059717117,0.000074543495,0.014198447,0.0000030937933,0.0000057567686,0.00011821831,0.000029095183,0.0015501968,0.9824891,0.00008351135,0.0014376236,0.000004487842],"about_ca_topic_score_codex":0.0005434596,"about_ca_topic_score_gemma":0.0010750792,"teacher_disagreement_score":0.0005434596,"about_ca_system_score_codex":0.00019836039,"about_ca_system_score_gemma":0.00011936319,"threshold_uncertainty_score":0.0014392138},"labels":[],"label_agreement":null},{"id":"W2042816955","doi":"10.1016/s0041-1345(00)02325-3","title":"ISATX247: a novel calcineurin inhibitor","year":2001,"lang":"en","type":"article","venue":"Transplantation Proceedings","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":63,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Calcineurin; Medicine; Pharmacology; Internal medicine; Transplantation","score_opus":0.015456727788457449,"score_gpt":0.2507375182724478,"score_spread":0.23528079048399034,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2042816955","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8883197,0.066359825,0.011624989,0.0029714822,0.0013026512,0.0005250433,0.0015616526,0.001968747,0.02536593],"genre_scores_gemma":[0.94836307,0.02389265,0.007525938,0.0010890235,0.00036984181,0.00034097087,0.0039747963,0.0001019257,0.014341864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991465,0.000012046573,0.00000640894,0.000014922648,0.000020925074,0.00003091511],"domain_scores_gemma":[0.99995077,0.000006360338,0.000009375144,0.000004255721,0.000005004461,0.000024248911],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018304901,0.0006819486,0.00064287236,0.00053884444,0.00043852624,0.00060588017,0.000793167,0.00062204193,0.0019032684],"category_scores_gemma":[0.00013808058,0.00015016609,0.00040001594,0.00040360427,0.00032137037,0.00030728042,0.00024065892,0.0013835746,0.0010698762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0033676138,0.0010604082,0.0011340833,0.0005200844,0.00017418827,0.0030641367,0.000083883155,0.0017553956,0.84615284,0.0025140587,0.007959926,0.1322133],"study_design_scores_gemma":[0.0039905147,0.012849247,0.007859007,0.00007000066,0.00055798027,0.014963567,0.00008513357,0.0035537148,0.82986146,0.001143746,0.12494763,0.000118025724],"about_ca_topic_score_codex":0.0005064853,"about_ca_topic_score_gemma":0.0008936198,"teacher_disagreement_score":0.0019032684,"about_ca_system_score_codex":0.00051160477,"about_ca_system_score_gemma":0.0006056461,"threshold_uncertainty_score":0.0063670874},"labels":[],"label_agreement":null},{"id":"W2043198676","doi":"10.1177/1753944711432901","title":"Angiotensin II signalling and calcineurin in cardiac fibroblasts: differential effects of calcineurin inhibitors FK506 and cyclosporine A","year":2011,"lang":"en","type":"article","venue":"Therapeutic Advances in Cardiovascular Disease","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research","keywords":"Calcineurin; Kinase; Angiotensin II; Mitogen-activated protein kinase; p38 mitogen-activated protein kinases; Fibrosis; Medicine; Inflammation; Endocrinology; Pharmacology; Receptor; MAPK/ERK pathway; Internal medicine; Cell biology; Biology; Transplantation","score_opus":0.008580800611984404,"score_gpt":0.22246711829667404,"score_spread":0.21388631768468963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2043198676","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860523,0.0109218955,0.00074647326,0.0001370798,0.00011399853,0.00003257984,0.0002387736,0.00003308807,0.0017237635],"genre_scores_gemma":[0.99364215,0.0038312366,0.0008726942,0.000074540665,0.000049505707,0.00004430385,0.00023482916,0.000007468479,0.0012432132],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980277,0.000038629136,0.000025894959,0.000033956996,0.000044642948,0.00005415239],"domain_scores_gemma":[0.9998355,0.000048086215,0.000028355207,0.000013912582,0.000025650139,0.000048444414],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015468385,0.00035981758,0.0003957355,0.0001688275,0.0002025421,0.00033962022,0.0001509852,0.0002994536,0.0010860447],"category_scores_gemma":[0.00012496852,0.000100097015,0.00026875763,0.0001816762,0.00024017184,0.00020357639,0.00011488856,0.0005575901,0.00018174255],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008452677,0.00011563184,0.00027142392,0.00012238762,0.000013572167,0.00007402449,0.00003343247,0.00007014462,0.99679095,0.000037591573,0.000043639273,0.0015819166],"study_design_scores_gemma":[0.000084318,0.0017852149,0.010688203,0.000014843097,0.00006585991,0.00026939827,0.0000637544,0.00064822467,0.9845018,0.000035496414,0.0018309423,0.000011939692],"about_ca_topic_score_codex":0.001137384,"about_ca_topic_score_gemma":0.0018546485,"teacher_disagreement_score":0.001137384,"about_ca_system_score_codex":0.0002106847,"about_ca_system_score_gemma":0.0002646077,"threshold_uncertainty_score":0.0036332011},"labels":[],"label_agreement":null},{"id":"W2044009184","doi":"10.1074/jbc.m606287200","title":"Protein Kinase C-dependent Enhancement of Activity of Rat Brain NCKX2 Heterologously Expressed in HEK293 Cells","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Libin Cardiovascular Institute of Alberta; University of Calgary","funders":"","keywords":"HEK 293 cells; Chemistry; Cell biology; Protein kinase A; Kinase; Molecular biology; Biology; Biochemistry; Gene","score_opus":0.013440887038064663,"score_gpt":0.24359251304243257,"score_spread":0.2301516260043679,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044009184","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.982988,0.002951037,0.007624402,0.00031093496,0.00021928769,0.00010225707,0.0026002035,0.00028757908,0.0029162613],"genre_scores_gemma":[0.9563293,0.003276852,0.015955823,0.00017988961,0.00009859234,0.00022070404,0.011000455,0.00012452487,0.012813797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995524,0.000048534177,0.00006763599,0.0001229693,0.00011098147,0.0000974091],"domain_scores_gemma":[0.99983823,0.000033920653,0.000029293931,0.000034708042,0.000029525068,0.000034191587],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003089348,0.00058538653,0.0006150816,0.00024394793,0.00022094043,0.00043901964,0.00033565846,0.000310258,0.0020707785],"category_scores_gemma":[0.00018934316,0.00020158917,0.0005389389,0.0004816075,0.0002586034,0.00037860812,0.00025865764,0.0011722378,0.0009821516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009434067,0.000026914102,0.000044490127,0.000044755503,0.000005074527,0.000021424545,0.000010449937,0.000018391846,0.9993703,0.000050666622,0.00003712648,0.00027603627],"study_design_scores_gemma":[0.00002644506,0.00010809724,0.0016535898,0.000004695678,0.00001379026,0.00015287378,0.000016219017,0.0007469234,0.9949805,0.000020929323,0.0022711158,0.0000047951007],"about_ca_topic_score_codex":0.0007973546,"about_ca_topic_score_gemma":0.0010800888,"teacher_disagreement_score":0.0020707785,"about_ca_system_score_codex":0.00047910563,"about_ca_system_score_gemma":0.00040499636,"threshold_uncertainty_score":0.0069274902},"labels":[],"label_agreement":null},{"id":"W2044317877","doi":"10.1016/j.pharmthera.2003.08.002","title":"Immunosuppression and transplant vascular disease: benefits and adverse effects","year":2003,"lang":"en","type":"review","venue":"Pharmacology & Therapeutics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":48,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; St. Paul's Hospital","funders":"","keywords":"Immunosuppression; Calcineurin; Immune system; Transplant rejection; Immunology; Pathogenesis; Transplantation; Medicine; Heart transplantation; Mechanism of action; Blockade; Receptor; Pharmacology; Biology; Internal medicine","score_opus":0.030878637645276066,"score_gpt":0.32408293340814354,"score_spread":0.2932042957628675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044317877","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00018746294,0.99691284,0.00034484183,0.00036109364,0.00039956084,0.0000050635126,0.000017017957,0.000012103637,0.0017600415],"genre_scores_gemma":[0.0010307158,0.9957535,0.00047329007,0.00038708965,0.0005037954,0.0000101641535,0.000028598219,0.0000026784812,0.0018100903],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998461,0.000023948929,0.000018279115,0.000025761465,0.000072900344,0.000012957137],"domain_scores_gemma":[0.9996339,0.00018963998,0.000042286243,0.0000137026955,0.000087871595,0.000032663098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006355389,0.0010968052,0.0019593355,0.0014617438,0.00034579032,0.0010066004,0.0009260287,0.0014562252,0.0046391212],"category_scores_gemma":[0.00061516516,0.00024125924,0.0003981478,0.0020075801,0.00062827725,0.0010934018,0.0003871857,0.0019282188,0.0028087893],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001469509,0.000106579726,0.0001800729,0.004247385,0.00006986397,0.00032535748,0.000025967332,0.00030344978,0.0027740865,0.0022726385,0.030416248,0.95913136],"study_design_scores_gemma":[0.00006321921,0.00017205557,0.0011965003,0.001272264,0.00015662702,0.00270204,0.000062466715,0.00011212988,0.0011566378,0.0025368917,0.9905475,0.000021632643],"about_ca_topic_score_codex":0.0008638078,"about_ca_topic_score_gemma":0.002701893,"teacher_disagreement_score":0.0046391212,"about_ca_system_score_codex":0.00047343806,"about_ca_system_score_gemma":0.0007033759,"threshold_uncertainty_score":0.015519381},"labels":[],"label_agreement":null},{"id":"W2044733823","doi":"10.1016/j.bbrc.2009.07.080","title":"Inhibition of matrix metalloproteinase-2 by PARP inhibitors","year":2009,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Institutes of Health","keywords":"Matrix metalloproteinase; Poly ADP ribose polymerase; Matrix metalloproteinase 9; Chemistry; Matrix metalloproteinase inhibitor; Metalloproteinase; Pharmacology; Biochemistry; Enzyme; Biology; Polymerase","score_opus":0.04020771411827828,"score_gpt":0.3619399806902611,"score_spread":0.32173226657198284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2044733823","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92692703,0.029246977,0.018533422,0.0021128196,0.0011894403,0.000307414,0.003529161,0.0010664096,0.017087478],"genre_scores_gemma":[0.97597164,0.009741922,0.004762842,0.0002486094,0.00013794204,0.00018120142,0.0023594243,0.000037613703,0.0065587335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99970347,0.000051282474,0.000035093355,0.00004080306,0.000060805316,0.00010855268],"domain_scores_gemma":[0.9998659,0.000041989322,0.000027279051,0.00002681894,0.000011627311,0.000026364703],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003377939,0.0006518454,0.00040497878,0.00032869924,0.0002503287,0.0005714175,0.00048525986,0.00038869333,0.0031476784],"category_scores_gemma":[0.00033069833,0.00033993542,0.0004947112,0.0002713038,0.00023438598,0.00040605542,0.0002347624,0.0014332025,0.0011490423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025453868,0.0005067499,0.00028176742,0.0002716137,0.000101989855,0.00035291724,0.000039596194,0.0007951383,0.970873,0.0011790269,0.003135228,0.019917559],"study_design_scores_gemma":[0.00024696664,0.0010637763,0.001465017,0.000007944599,0.000034324876,0.0006100833,0.00001791409,0.0012784944,0.9863469,0.00016788629,0.008748458,0.00001224768],"about_ca_topic_score_codex":0.00043197256,"about_ca_topic_score_gemma":0.00061965885,"teacher_disagreement_score":0.0031476784,"about_ca_system_score_codex":0.0003692452,"about_ca_system_score_gemma":0.0003404219,"threshold_uncertainty_score":0.010530055},"labels":[],"label_agreement":null},{"id":"W2046002103","doi":"10.1038/nature04105","title":"Intrinsic dynamics of an enzyme underlies catalysis","year":2005,"lang":"en","type":"article","venue":"Nature","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1114,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; National Institutes of Health; Vetenskapsrådet; National High Magnetic Field Laboratory","keywords":"Enzyme catalysis; Chemistry; Protein dynamics; Catalysis; Enzyme; Function (biology); Cypa; Protein structure; Isomerase; Active site; Molecular dynamics; Protein engineering; Biophysics; Stereochemistry; Cyclophilin A; Computational chemistry; Biochemistry; Biology","score_opus":0.004836684631991604,"score_gpt":0.24995879494138518,"score_spread":0.24512211030939357,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046002103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.78607315,0.0026739216,0.1903939,0.002408813,0.00047325977,0.00005896844,0.00017106603,0.0006235571,0.017123407],"genre_scores_gemma":[0.9948119,0.0005989409,0.003394476,0.000046958783,0.00004078457,0.000020319245,0.00005283435,0.00003244709,0.0010013685],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996947,0.000036140093,0.000020177682,0.000112281676,0.000085554566,0.0000512349],"domain_scores_gemma":[0.9993356,0.00032068213,0.00006332517,0.0001610914,0.00005051583,0.0000686822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007431825,0.00041229886,0.0005894596,0.00026572894,0.00042607522,0.0015618495,0.0010667812,0.00093781354,0.0017493615],"category_scores_gemma":[0.0024071306,0.0004963502,0.00043864563,0.00019655975,0.001446885,0.0024052947,0.00092984684,0.0015687646,0.0005905404],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003036584,0.0001420215,0.004274595,0.00038212724,0.000109671215,0.0009579373,0.00041402667,0.024075681,0.4056762,0.53431195,0.0013639871,0.027988227],"study_design_scores_gemma":[0.0000946443,0.00032575754,0.0031188496,0.000033371252,0.00007091255,0.0016823463,0.00021980166,0.2734003,0.29184818,0.41919774,0.009888922,0.00011914131],"about_ca_topic_score_codex":0.00024638526,"about_ca_topic_score_gemma":0.00016196254,"teacher_disagreement_score":0.0017493615,"about_ca_system_score_codex":0.0007511421,"about_ca_system_score_gemma":0.00041590453,"threshold_uncertainty_score":0.0058522224},"labels":[],"label_agreement":null},{"id":"W2046146856","doi":"10.1074/jbc.m510217200","title":"Myocyte Enhancer Factors 2A and 2C Induce Dilated Cardiomyopathy in Transgenic Mice","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":191,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Heart and Stroke Foundation","funders":"","keywords":"Mef2; MEF2C; Biology; Myocyte; Transcription factor; Calcineurin; Transgene; Signal transduction; Cell biology; Enhancer; Pressure overload; Muscle hypertrophy; Internal medicine; Molecular biology; Endocrinology; Medicine; Gene; Transplantation; Genetics","score_opus":0.015036642450072735,"score_gpt":0.2397436560357864,"score_spread":0.22470701358571366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046146856","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9609885,0.0023025875,0.016412945,0.0012519035,0.00066566,0.0008895172,0.00844626,0.0023931935,0.006649339],"genre_scores_gemma":[0.93001294,0.0023988273,0.020876842,0.0010924499,0.00029517463,0.0028359473,0.009930861,0.0013473833,0.031209651],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99865615,0.00019027147,0.00017889084,0.00041872042,0.0003168493,0.00023905389],"domain_scores_gemma":[0.9985397,0.00025642817,0.000585762,0.00012783738,0.000079593505,0.0004106552],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009284446,0.0017572808,0.00082599354,0.0028508569,0.00067008927,0.0007411244,0.0011415739,0.0026711875,0.0063750353],"category_scores_gemma":[0.00050452806,0.0012709869,0.0011316205,0.0006936193,0.0011841841,0.0004989647,0.00072973175,0.0025072086,0.0018179952],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043619858,0.0003250555,0.0003181773,0.0000724584,0.000034686702,0.0003564394,0.000071514994,0.00017143224,0.9958331,0.0008435267,0.00036928224,0.0011682523],"study_design_scores_gemma":[0.0017366802,0.0020589149,0.013822511,0.00017460939,0.0002145247,0.0028361315,0.00014872309,0.007988629,0.94518304,0.00074808137,0.02501089,0.00007734232],"about_ca_topic_score_codex":0.0013613559,"about_ca_topic_score_gemma":0.002655454,"teacher_disagreement_score":0.0063750353,"about_ca_system_score_codex":0.0013771829,"about_ca_system_score_gemma":0.0006551635,"threshold_uncertainty_score":0.021326661},"labels":[],"label_agreement":null},{"id":"W2046192271","doi":"10.1074/jbc.m110.160101","title":"Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain","year":2010,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":99,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Division of Materials Research; National Center for Research Resources; National Institute of General Medical Sciences; Canadian Institutes of Health Research; National Institutes of Health; National Science Foundation","keywords":"Calnexin; Calreticulin; Endoplasmic reticulum; Cyclophilin; Protein disulfide-isomerase; Chaperone (clinical); Isomerase; Protein folding; Prolyl isomerase; Chemistry; Biochemistry; Biology; Cell biology; PIN1; Enzyme","score_opus":0.012593974709902702,"score_gpt":0.2496753155294405,"score_spread":0.2370813408195378,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046192271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99569255,0.0007989134,0.0016054381,0.00021187881,0.000018701583,0.000013792775,0.00007509446,0.000037851518,0.0015457335],"genre_scores_gemma":[0.9976503,0.00032833582,0.0012110213,0.00011777925,0.0000054078673,0.000005586016,0.0001845271,0.000006832365,0.0004902787],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999285,0.000013971717,0.0000043950254,0.000018340412,0.000017429142,0.000017401371],"domain_scores_gemma":[0.99993193,0.000013090432,0.000014323722,0.00000415671,0.000009246009,0.000027178772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006675426,0.00021619457,0.000157938,0.00010323326,0.00023555115,0.0002605223,0.00025717632,0.0003193153,0.0011103727],"category_scores_gemma":[0.00012364534,0.0001245905,0.00018425481,0.000077426535,0.00017108979,0.00012011265,0.00015503883,0.00045185428,0.00039770963],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016523623,0.000060560942,0.0014338043,0.00005999014,0.000016975124,0.00042108566,0.000023635557,0.00072690356,0.9944094,0.00059135404,0.00017984491,0.0019112276],"study_design_scores_gemma":[0.00011480646,0.0003745316,0.03501778,0.000023630728,0.000045260687,0.0013726829,0.00016626113,0.0211686,0.93445146,0.0010775205,0.0061607654,0.00002675762],"about_ca_topic_score_codex":0.0014174411,"about_ca_topic_score_gemma":0.0012548615,"teacher_disagreement_score":0.0014174411,"about_ca_system_score_codex":0.0004866502,"about_ca_system_score_gemma":0.00023416596,"threshold_uncertainty_score":0.0037145615},"labels":[],"label_agreement":null},{"id":"W2046589471","doi":"10.1007/s00395-011-0161-4","title":"Activated NHE1 is required to induce early cardiac hypertrophy in mice","year":2011,"lang":"en","type":"article","venue":"Basic Research in Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Internal medicine; Muscle hypertrophy; Endocrinology; Genetically modified mouse; Biology; GATA4; Calcineurin; Sodium–hydrogen antiporter; Transgene; Chemistry; Gene expression; Medicine; Biochemistry; Sodium; Gene; Transplantation","score_opus":0.1311700890940988,"score_gpt":0.3556068760580004,"score_spread":0.2244367869639016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046589471","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97998,0.0025131232,0.008490199,0.0012390456,0.00037260933,0.00012180214,0.0030249637,0.0009086279,0.003349545],"genre_scores_gemma":[0.9809286,0.0012966302,0.0048553785,0.00042084663,0.00010474582,0.00021300599,0.0018608086,0.00046184985,0.009858089],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993339,0.000080648526,0.0000724991,0.00019070007,0.00013778369,0.00018430514],"domain_scores_gemma":[0.9985274,0.00020915692,0.00058936514,0.0001506801,0.00005172412,0.00047159416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005041749,0.0013278851,0.00075653486,0.0013919525,0.00046430796,0.00084067945,0.0008876502,0.0014492694,0.005328921],"category_scores_gemma":[0.00039772407,0.00088669534,0.0010095455,0.00039971463,0.0012573346,0.0007879621,0.0006845004,0.003864924,0.0015583683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041915345,0.000081483384,0.00009316031,0.000040524086,0.000010499862,0.00013129266,0.000012111666,0.00006432123,0.9983308,0.000253178,0.000070806964,0.0004926218],"study_design_scores_gemma":[0.00021030063,0.00040789656,0.0039732354,0.000023603674,0.0000492407,0.00064674835,0.000058009326,0.0008634997,0.99102914,0.00031141387,0.0024100293,0.000016871825],"about_ca_topic_score_codex":0.00047311006,"about_ca_topic_score_gemma":0.0011451358,"teacher_disagreement_score":0.005328921,"about_ca_system_score_codex":0.0008083012,"about_ca_system_score_gemma":0.00044869867,"threshold_uncertainty_score":0.017827034},"labels":[],"label_agreement":null},{"id":"W2046624043","doi":"10.1016/j.cellsig.2014.04.005","title":"The prolyl isomerase Pin1 regulates hypoxia-inducible transcription factor (HIF) activity","year":2014,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hôtel-Dieu de Québec; Université Laval","funders":"National Cancer Institute; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"PIN1; Prolyl isomerase; Phosphorylation; Transcription factor; Peptidylprolyl isomerase; Cell biology; MAPK/ERK pathway; Kinase; Hypoxia-Inducible Factor 1; Immunoprecipitation; Biology; Chemistry; Transcription (linguistics); Biochemistry; Isomerase; Gene","score_opus":0.01583045515850059,"score_gpt":0.22351877927683694,"score_spread":0.20768832411833635,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2046624043","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95989054,0.013153597,0.0134240845,0.0009011859,0.0002185783,0.00004309463,0.0012051355,0.00031596204,0.0108478945],"genre_scores_gemma":[0.99052376,0.0023580503,0.0018408948,0.00016114702,0.000028398901,0.000012574348,0.0007690094,0.000042805023,0.0042632087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998578,0.000014650166,0.0000051628886,0.0000444038,0.000029349734,0.00004870589],"domain_scores_gemma":[0.9998921,0.0000124336475,0.000036015714,0.0000068344675,0.000016572165,0.00003606067],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015317266,0.0003279649,0.00020517193,0.00027997332,0.00032110422,0.00074343185,0.00024753052,0.00030013695,0.0023543863],"category_scores_gemma":[0.00024677458,0.00021696069,0.00019746195,0.00016182331,0.00023882915,0.00046549697,0.0005009297,0.00056978536,0.00092218805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035732117,0.000017989549,0.0010980119,0.0000738564,0.000010732313,0.00017191085,0.000025692992,0.00017027478,0.98926044,0.00080808747,0.00037957355,0.007626192],"study_design_scores_gemma":[0.000017587254,0.0001496019,0.020901615,0.000016050119,0.000016886517,0.0008121015,0.00010762348,0.0016306416,0.96675885,0.00055388117,0.009018433,0.000016638214],"about_ca_topic_score_codex":0.0005018457,"about_ca_topic_score_gemma":0.0006461315,"teacher_disagreement_score":0.0023543863,"about_ca_system_score_codex":0.0005114753,"about_ca_system_score_gemma":0.00019814227,"threshold_uncertainty_score":0.007876217},"labels":[],"label_agreement":null},{"id":"W2047734512","doi":"10.1021/bi035432b","title":"Metal Ion Binding Properties and Conformational States of Calcium- and Integrin-Binding Protein","year":2004,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":82,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; Biophysics; Conformational change; Calcium; Protein structure; Calcium-binding protein; Calmodulin; Binding site; Integrin; Binding domain; EF hand; Protein secondary structure; Biochemistry; Plasma protein binding; Receptor; Biology","score_opus":0.022342054552828717,"score_gpt":0.23766054257938385,"score_spread":0.21531848802655512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2047734512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99808323,0.0007530542,0.0006128381,0.000034245102,0.0000051648303,0.0000040375353,0.00007696086,0.000010801296,0.00041963055],"genre_scores_gemma":[0.9985246,0.00020770627,0.00051467516,0.000039286835,0.0000052094438,0.000009054266,0.00024020358,0.000009833019,0.00044933983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980575,0.000030549396,0.000009076611,0.000060100192,0.000049471593,0.000045093915],"domain_scores_gemma":[0.99980253,0.000056886834,0.00005271247,0.000012949878,0.000030631214,0.000044326203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022077175,0.0002395635,0.00020619783,0.00020701713,0.00018467061,0.00032482983,0.0003208545,0.00033610134,0.00095677923],"category_scores_gemma":[0.0006359869,0.00018824561,0.00011038149,0.00021763965,0.00030820788,0.00023027475,0.00012901635,0.00033652023,0.00021681574],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026825865,0.00001897402,0.0013558933,0.000028290277,0.000012542138,0.000035196033,0.000050499097,0.000116160154,0.99713033,0.00008276185,0.000044241682,0.0008567196],"study_design_scores_gemma":[0.000057118865,0.00037433914,0.06683047,0.000011170427,0.000026885771,0.00052363175,0.00010838656,0.0048868377,0.9248013,0.00022863237,0.0021158142,0.000035495483],"about_ca_topic_score_codex":0.0011307617,"about_ca_topic_score_gemma":0.0005434598,"teacher_disagreement_score":0.0011307617,"about_ca_system_score_codex":0.0003346794,"about_ca_system_score_gemma":0.000083730214,"threshold_uncertainty_score":0.0032007098},"labels":[],"label_agreement":null},{"id":"W2048325051","doi":"10.1021/jm200156c","title":"Discovery and Characterization of a Nonphosphorylated Cyclic Peptide Inhibitor of the Peptidylprolyl Isomerase, Pin1","year":2011,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; PIN1; Peptidylprolyl isomerase; Isomerase; Peptide; Cis-trans-Isomerases; Cyclic peptide; Biochemistry; Enzyme","score_opus":0.009120501929226626,"score_gpt":0.20648511012575071,"score_spread":0.1973646081965241,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2048325051","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891061,0.0017553184,0.0065086265,0.00009016551,0.000015246135,0.00008410218,0.00033795144,0.000057022047,0.002045554],"genre_scores_gemma":[0.9897427,0.00093031186,0.0060106795,0.00006280192,0.000007686946,0.000033313285,0.0012012701,0.000018466584,0.0019927798],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991536,0.000009252815,0.0000046948126,0.000016586924,0.00003642477,0.000017677412],"domain_scores_gemma":[0.9999045,0.000017821676,0.000019898303,0.000007661295,0.000017642258,0.000032460903],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013349012,0.00027374257,0.00022640525,0.00018320125,0.000086962464,0.0002827575,0.00025319113,0.0002692131,0.00076310174],"category_scores_gemma":[0.00024400889,0.00011340402,0.0001640895,0.00012100888,0.00017022117,0.0001363263,0.00012915753,0.00042236815,0.00024270861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033104476,0.000014597626,0.00012466862,0.000016142758,0.0000026347632,0.000049355498,0.000004753822,0.00016722118,0.9979752,0.000057999296,0.000016989528,0.0015374214],"study_design_scores_gemma":[0.000010444416,0.0003288385,0.0016704464,0.0000027954,0.0000075272087,0.00046136513,0.000008810149,0.0012385653,0.9943658,0.000029734256,0.0018711537,0.0000044727867],"about_ca_topic_score_codex":0.0003952073,"about_ca_topic_score_gemma":0.00048405645,"teacher_disagreement_score":0.00076310174,"about_ca_system_score_codex":0.00030469985,"about_ca_system_score_gemma":0.0002014422,"threshold_uncertainty_score":0.0025528073},"labels":[],"label_agreement":null},{"id":"W2049205589","doi":"10.1074/jbc.m114.570911","title":"Depletion of Cyclophilins B and C Leads to Dysregulation of Endoplasmic Reticulum Redox Homeostasis","year":2014,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Endoplasmic reticulum; Cyclophilin; Protein disulfide-isomerase; Unfolded protein response; Isomerase; Biochemistry; Proteostasis; Cyclophilin A; Secretion; Chemistry; Protein folding; Glutathione; Secretory protein; Cell biology; Biology; Enzyme; Molecular biology","score_opus":0.0115514835671834,"score_gpt":0.24085177663318114,"score_spread":0.22930029306599772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049205589","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99607015,0.0009904542,0.0016387044,0.00007526657,0.00002152066,0.000015254658,0.0004121687,0.00005731902,0.000719253],"genre_scores_gemma":[0.99637246,0.00063369644,0.0010145388,0.00006792498,0.000007857175,0.000025100962,0.00060988945,0.000015941756,0.001252582],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986005,0.000022643937,0.00001783826,0.000032639935,0.000030138564,0.00003661846],"domain_scores_gemma":[0.9998771,0.000021160842,0.000027600101,0.000019795987,0.000011123101,0.00004324472],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010800464,0.00030064615,0.00025958705,0.00019282209,0.00014106334,0.00025349983,0.0001383501,0.00027665042,0.00080209546],"category_scores_gemma":[0.000087707675,0.000107711945,0.0002155191,0.00015591961,0.00018154546,0.00012020523,0.00016990058,0.00046430418,0.00024501554],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009051515,0.000009027836,0.00012937658,0.000013562758,0.000006480066,0.00003241093,0.0000035102623,0.000028938712,0.9992073,0.000027589978,0.000021956115,0.00042938595],"study_design_scores_gemma":[0.000012909196,0.00013663576,0.007131036,0.0000033459758,0.000020659627,0.00022929827,0.000022292117,0.0008407271,0.9902098,0.000026899223,0.0013624962,0.0000039434176],"about_ca_topic_score_codex":0.0006230168,"about_ca_topic_score_gemma":0.0006953083,"teacher_disagreement_score":0.00080209546,"about_ca_system_score_codex":0.00022034087,"about_ca_system_score_gemma":0.00016436796,"threshold_uncertainty_score":0.002683282},"labels":[],"label_agreement":null},{"id":"W2049419164","doi":"10.1038/sj.emboj.7600378","title":"Two WXXF‐based motifs in NECAPs define the specificity of accessory protein binding to AP‐1 and AP‐2","year":2004,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Killam Trusts; McGill University","keywords":"Biology; Computational biology; Plasma protein binding; Genetics; Cell biology","score_opus":0.023350845119109627,"score_gpt":0.2754346993989597,"score_spread":0.2520838542798501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2049419164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9887664,0.00063317915,0.009297239,0.000070191825,0.000023360923,0.000020220354,0.000119445765,0.00005379911,0.001016249],"genre_scores_gemma":[0.99324894,0.00016998893,0.0045668534,0.00006902549,0.000008274409,0.000020378497,0.00025253964,0.000024462035,0.0016395805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998197,0.00002868552,0.00002450691,0.000044936904,0.00003252539,0.000049645267],"domain_scores_gemma":[0.99966323,0.000055785684,0.000089762994,0.000048808135,0.000043070566,0.000099416975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026316204,0.00042213892,0.00034681952,0.00018885543,0.0003397577,0.00074482174,0.0003575418,0.0006101217,0.0016436122],"category_scores_gemma":[0.00038655227,0.00030099234,0.00044400775,0.00012724902,0.00050875434,0.00068118016,0.0007340624,0.0010212054,0.0009360883],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003220516,0.00001796662,0.0006851596,0.000025539248,0.00001116812,0.00021598296,0.000036047935,0.000160205,0.99581784,0.0008018682,0.00004365,0.0018625156],"study_design_scores_gemma":[0.000037661644,0.00014468555,0.015556082,0.00001449747,0.00001981535,0.001492884,0.000077278586,0.0021977262,0.9777935,0.0005370227,0.0021073176,0.000021521795],"about_ca_topic_score_codex":0.00034275485,"about_ca_topic_score_gemma":0.00044591835,"teacher_disagreement_score":0.0016436122,"about_ca_system_score_codex":0.00035467197,"about_ca_system_score_gemma":0.00018201969,"threshold_uncertainty_score":0.0054984093},"labels":[],"label_agreement":null},{"id":"W2051009120","doi":"10.1002/jnr.10369","title":"Low‐density lipoprotein receptor‐related protein mediates in PC12 cell cultures the inhibition of nerve growth factor‐promoted neurite outgrowth by pregnancy zone protein and α<sub>2</sub>‐macroglobulin","year":2002,"lang":"en","type":"article","venue":"Journal of Neuroscience Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Universidad de Córdoba; International Union of Biochemistry and Molecular Biology; Universidad Nacional de Córdoba","keywords":"Neurite; Trk receptor; Tropomyosin receptor kinase A; Receptor; Cell biology; Nerve growth factor; Macroglobulin; Chemistry; Signal transduction; Endocrinology; Biology; Internal medicine; Biochemistry; In vitro; Medicine","score_opus":0.023679112488573836,"score_gpt":0.27352565034920073,"score_spread":0.24984653786062688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051009120","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989556,0.0061845593,0.0017110993,0.000057314483,0.00003126213,0.000029752968,0.00033580192,0.00009817895,0.0019959772],"genre_scores_gemma":[0.98276466,0.006642273,0.003248128,0.00004825253,0.000020932686,0.00011028442,0.0012125243,0.000026170574,0.0059267096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998708,0.00002065795,0.000012432054,0.000022259717,0.00003130161,0.000042516996],"domain_scores_gemma":[0.99989676,0.000024565594,0.000018398534,0.000016692413,0.000017018263,0.00002654262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013012782,0.00058675086,0.00047348655,0.00020824732,0.00018408395,0.00029324475,0.000287625,0.00020877797,0.0008743939],"category_scores_gemma":[0.0001183318,0.00018838602,0.0005476142,0.00020985608,0.00018109007,0.0002066448,0.00026157833,0.00048870046,0.0008461549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030801937,0.00004327678,0.0001786047,0.00010180414,0.000013581705,0.00010334659,0.000035844947,0.00003937173,0.9970854,0.000043820084,0.00004958505,0.0019974776],"study_design_scores_gemma":[0.000046719302,0.0008919537,0.014610348,0.000016932217,0.00004919571,0.0004507305,0.00005581451,0.0010772076,0.9795212,0.000040778417,0.0032285254,0.0000105768895],"about_ca_topic_score_codex":0.0036563254,"about_ca_topic_score_gemma":0.005416779,"teacher_disagreement_score":0.0036563254,"about_ca_system_score_codex":0.00034788682,"about_ca_system_score_gemma":0.00033976647,"threshold_uncertainty_score":0.0072700977},"labels":[],"label_agreement":null},{"id":"W2051532990","doi":"10.1074/jbc.m113.474932","title":"Mitotic Regulation of SEPT9 Protein by Cyclin-dependent Kinase 1 (Cdk1) and Pin1 Protein Is Important for the Completion of Cytokinesis","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Western University; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Cytokinesis; Cell biology; Cyclin-dependent kinase 1; Mitosis; PIN1; Biology; Chemistry; Cell cycle; Genetics; Cell division; Cell; Isomerase","score_opus":0.016935455496760916,"score_gpt":0.24284728083734752,"score_spread":0.2259118253405866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051532990","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9781702,0.008565634,0.006598994,0.00032868245,0.000083312996,0.000043930962,0.0011377999,0.0002031078,0.0048683947],"genre_scores_gemma":[0.99167585,0.002811608,0.0020712109,0.000039272567,0.000014633382,0.000023143915,0.00068071677,0.000019252857,0.0026643097],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999254,0.000008402402,0.000007388228,0.000022690898,0.000019163643,0.000016998361],"domain_scores_gemma":[0.9998826,0.000011533994,0.000056527144,0.000006861328,0.000013380676,0.000029141447],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009076232,0.00032074747,0.00013343985,0.00022378136,0.0003296165,0.00033315076,0.0001616942,0.00018930434,0.001781166],"category_scores_gemma":[0.00014507982,0.00014887951,0.00015388415,0.000108209075,0.00022815922,0.00022579341,0.00027167035,0.000321903,0.0007609131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002187962,0.000018845236,0.0020984495,0.00014911444,0.000007956976,0.00025321209,0.00001893627,0.00024357067,0.99007916,0.00069891266,0.00028128893,0.0059317667],"study_design_scores_gemma":[0.000020438973,0.000102844555,0.035043195,0.000022758179,0.000014853342,0.0011857679,0.000043503787,0.0020383499,0.9472923,0.00034442483,0.013882262,0.000009233211],"about_ca_topic_score_codex":0.0003682444,"about_ca_topic_score_gemma":0.00060918095,"teacher_disagreement_score":0.001781166,"about_ca_system_score_codex":0.00037695776,"about_ca_system_score_gemma":0.00022152513,"threshold_uncertainty_score":0.0059586167},"labels":[],"label_agreement":null},{"id":"W2051619902","doi":"10.1074/jbc.c100195200","title":"Cyclic AMP-independent Activation of Protein Kinase A by Vasoactive Peptides","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences","keywords":"Vasoactive; Protein kinase A; Chemistry; Vasoactive intestinal peptide; Internal medicine; Biochemistry; Kinase; Medicine; Neuropeptide; Receptor","score_opus":0.022162375671910785,"score_gpt":0.2649051736553144,"score_spread":0.24274279798340362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2051619902","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88691914,0.0798671,0.0146232955,0.0009728557,0.0006502624,0.00028615355,0.0012772797,0.00018020785,0.015223655],"genre_scores_gemma":[0.9606536,0.027482513,0.005731047,0.0002891622,0.00025946597,0.00014398771,0.00104332,0.000014374341,0.0043825237],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998387,0.00002100746,0.000011145493,0.00005280761,0.00003444328,0.000041836935],"domain_scores_gemma":[0.99994624,0.000008997145,0.000017164846,0.00000697779,0.000007156471,0.00001350495],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001242621,0.0005201671,0.00023904488,0.00028148017,0.00032421263,0.00031475857,0.0002887801,0.00032886225,0.0012576453],"category_scores_gemma":[0.00010417975,0.00012689388,0.00043540366,0.00020113261,0.00029395323,0.0003299825,0.00027464263,0.00068215333,0.00047374613],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014874044,0.00008226684,0.00013844683,0.00027557244,0.000011353198,0.00013558284,0.000016426591,0.000112076086,0.9946965,0.0003354367,0.00010004024,0.0039474685],"study_design_scores_gemma":[0.00006177735,0.0007136127,0.007177386,0.000039008813,0.000028053324,0.0008711663,0.000052240495,0.0011553688,0.9748277,0.0005303987,0.014523655,0.000019555897],"about_ca_topic_score_codex":0.00044268285,"about_ca_topic_score_gemma":0.0006018689,"teacher_disagreement_score":0.0012576453,"about_ca_system_score_codex":0.00045953933,"about_ca_system_score_gemma":0.00027821606,"threshold_uncertainty_score":0.004207313},"labels":[],"label_agreement":null},{"id":"W2052460475","doi":"10.1097/00007890-200110150-00001","title":"RAPAMYCIN: CLINICAL RESULTS AND FUTURE OPPORTUNITIES1","year":2001,"lang":"en","type":"review","venue":"Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":226,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"U.S. Public Health Service","keywords":"Intensive care medicine; Medicine","score_opus":0.10591750805492234,"score_gpt":0.38736365462189914,"score_spread":0.2814461465669768,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2052460475","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011476583,0.93538785,0.00071784796,0.034092437,0.005275411,0.000045058026,0.00034350003,0.00013835068,0.022851802],"genre_scores_gemma":[0.010085694,0.9357908,0.0020084458,0.025048764,0.015129205,0.00009664944,0.00085800036,0.000074946256,0.010907606],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990361,0.0003109553,0.00011722272,0.00012948745,0.00028268047,0.00012352904],"domain_scores_gemma":[0.9983798,0.0004942008,0.00018018903,0.00009027646,0.0005234429,0.0003320878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0029891576,0.000947058,0.0009657103,0.0011976423,0.00038366523,0.0027082323,0.00081425294,0.0023898555,0.02198473],"category_scores_gemma":[0.002878879,0.00021708403,0.00069489196,0.0011148263,0.0010650028,0.0025636922,0.0010743493,0.0033645637,0.011020939],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006662133,0.00020527096,0.00041224406,0.002887851,0.00005190627,0.0002472659,0.00005681537,0.00015652482,0.0012491768,0.005769102,0.12606208,0.8622355],"study_design_scores_gemma":[0.00012365007,0.00080206135,0.00085424475,0.003002228,0.00008037651,0.0010047893,0.00007337583,0.00007993086,0.00065845624,0.0039675715,0.989331,0.000022309492],"about_ca_topic_score_codex":0.0003478004,"about_ca_topic_score_gemma":0.0008319122,"teacher_disagreement_score":0.02198473,"about_ca_system_score_codex":0.0008751462,"about_ca_system_score_gemma":0.0015475831,"threshold_uncertainty_score":0.07354623},"labels":[],"label_agreement":null},{"id":"W2053411194","doi":"10.1074/jbc.m209900200","title":"Cardiac-specific Expression of Calcineurin Reverses Embryonic Lethality in Calreticulin-deficient Mouse","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":107,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Canadian Institutes of Health Research; University of Alberta","funders":"","keywords":"Lethality; Calreticulin; Calcineurin; Embryonic stem cell; Cell biology; Expression (computer science); Biology; Andrology; Medicine; Internal medicine; Genetics; Transplantation; Endoplasmic reticulum; Gene; Computer science","score_opus":0.036032253035093734,"score_gpt":0.2561816411836186,"score_spread":0.22014938814852486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053411194","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98686427,0.0015971571,0.0073551666,0.00036352078,0.00009462292,0.0000905176,0.0006590102,0.00055549736,0.002420101],"genre_scores_gemma":[0.9784328,0.0019009849,0.0087786885,0.00016740069,0.000048079026,0.00012317236,0.0012782787,0.00023696829,0.009033665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997062,0.000040239094,0.000037997503,0.000077749,0.000075653654,0.000062032916],"domain_scores_gemma":[0.999622,0.00005063615,0.000121162746,0.000047380458,0.00003261785,0.0001261355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027274375,0.00058503705,0.00040917745,0.0006390465,0.00021004985,0.00043454455,0.00051958783,0.0005766211,0.0011997283],"category_scores_gemma":[0.00020253785,0.00030045875,0.00028164042,0.00023642575,0.00054231856,0.00026816945,0.00027427,0.0013495871,0.000547916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007146245,0.000028370985,0.0000689552,0.00002132556,0.0000042735364,0.000082627885,0.000014600663,0.00004303246,0.99869126,0.00019414748,0.00003175597,0.0007481759],"study_design_scores_gemma":[0.00007661551,0.0003392703,0.0026482705,0.000014794845,0.000029073342,0.0005406151,0.000027363369,0.0011054161,0.9910164,0.0001333174,0.0040608393,0.000007946527],"about_ca_topic_score_codex":0.0004493885,"about_ca_topic_score_gemma":0.0009126581,"teacher_disagreement_score":0.0011997283,"about_ca_system_score_codex":0.00037643884,"about_ca_system_score_gemma":0.00036065365,"threshold_uncertainty_score":0.0040134788},"labels":[],"label_agreement":null},{"id":"W2054704883","doi":"10.1096/fj.09-137646","title":"Proteinase‐activated receptors induce interleukin‐8 expression by intestinal epithelial cells through ERK/RSK90 activation and histone acetylation","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Phosphorylation; MAPK/ERK pathway; Cell biology; Kinase; Protease-activated receptor; Signal transduction; Chemistry; Inflammation; Carcinogenesis; Molecular biology; Receptor; Biology; Cancer research; Biochemistry; Immunology; Gene","score_opus":0.011807474681731642,"score_gpt":0.25619393270871144,"score_spread":0.24438645802697978,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2054704883","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9943171,0.0015512885,0.0015116794,0.00012731935,0.00003351529,0.000033207885,0.0002914864,0.000077234356,0.0020570832],"genre_scores_gemma":[0.99556965,0.00073783624,0.0011564745,0.000056486795,0.000013315885,0.00002780652,0.00044860115,0.000008174267,0.0019816963],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984884,0.000027791151,0.000011160155,0.000016777361,0.00003598731,0.00005931222],"domain_scores_gemma":[0.99995756,0.000006571895,0.000012528592,0.0000074904738,0.0000049599553,0.000010809885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009035161,0.00027746244,0.00020490214,0.00012877127,0.00009041333,0.00020413092,0.000088997636,0.00013147046,0.0016224633],"category_scores_gemma":[0.00009635577,0.0001356317,0.00029713294,0.00012983136,0.00012870645,0.00015384481,0.00020225474,0.00046896088,0.00056892284],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001784244,0.000035816516,0.00014192156,0.000040101422,0.0000046311466,0.00009065775,0.000013081791,0.00003094498,0.9982822,0.000051362513,0.000059291957,0.001071627],"study_design_scores_gemma":[0.00008652503,0.0005941818,0.019950127,0.0000078561625,0.000022683444,0.0005542112,0.0000726474,0.001422416,0.9739246,0.00010450089,0.0032520513,0.000008268975],"about_ca_topic_score_codex":0.00030625827,"about_ca_topic_score_gemma":0.0005348126,"teacher_disagreement_score":0.0016224633,"about_ca_system_score_codex":0.00016535452,"about_ca_system_score_gemma":0.00011269427,"threshold_uncertainty_score":0.005427718},"labels":[],"label_agreement":null},{"id":"W2055089287","doi":"10.1007/s11060-008-9682-6","title":"Zhangfei induces the expression of the nerve growth factor receptor, trkA, in medulloblastoma cells and causes their differentiation or apoptosis","year":2008,"lang":"en","type":"article","venue":"Journal of Neuro-Oncology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Cameco (Canada); University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto; University of Saskatchewan","keywords":"Nerve growth factor; Tropomyosin receptor kinase A; Low-affinity nerve growth factor receptor; Biology; Cell biology; Resveratrol; Cellular differentiation; Cancer research; Receptor; Pharmacology; Gene; Genetics","score_opus":0.02843185212513465,"score_gpt":0.2612461998309,"score_spread":0.23281434770576537,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055089287","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919322,0.0020373466,0.001962757,0.00016729605,0.00005727322,0.000025366095,0.00041094428,0.00012930535,0.0032775882],"genre_scores_gemma":[0.99012005,0.00083277316,0.0010902216,0.000057286798,0.000013827333,0.000029926088,0.0008930374,0.000017338696,0.0069455667],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989986,0.000008157702,0.0000065125023,0.000015599397,0.000027988655,0.00004177219],"domain_scores_gemma":[0.99996376,0.0000041514504,0.000008432683,0.000004843568,0.000004218254,0.000014574192],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000070138194,0.000292584,0.00025940497,0.00031864477,0.00023910415,0.00021306502,0.00017120613,0.00019968666,0.002114703],"category_scores_gemma":[0.00006118463,0.00016129014,0.0003247196,0.00028427175,0.00014729027,0.0001483986,0.00014996763,0.00057622936,0.00035676363],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021419964,0.000047254383,0.0003199751,0.00003434736,0.000008481136,0.00011583128,0.000015381862,0.00004375604,0.9968727,0.00015309661,0.00015553186,0.002019527],"study_design_scores_gemma":[0.000025495265,0.00020569802,0.0037865113,0.0000015223286,0.00001418262,0.00022334357,0.000024683795,0.0003684872,0.99247825,0.000052029885,0.0028162359,0.0000035651483],"about_ca_topic_score_codex":0.0014569953,"about_ca_topic_score_gemma":0.0024309233,"teacher_disagreement_score":0.002114703,"about_ca_system_score_codex":0.00032595656,"about_ca_system_score_gemma":0.0002840401,"threshold_uncertainty_score":0.0070744157},"labels":[],"label_agreement":null},{"id":"W2055118323","doi":"10.1021/pr030003l","title":"Processing of Serum Proteins Underlies the Mass Spectral Fingerprinting of Myocardial Infarction","year":2003,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":230,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Research Canada","funders":"Vlaamse regering","keywords":"Peptide; Fibrinogen; Aminopeptidase; Myocardial infarction; Ex vivo; Cleavage (geology); Chemistry; Protease; Biochemistry; Biology; Medicine; Internal medicine; In vitro; Enzyme; Leucine; Amino acid","score_opus":0.04933648920227166,"score_gpt":0.3467892312445776,"score_spread":0.29745274204230593,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055118323","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947168,0.0014296502,0.002488496,0.00010743436,0.000013331022,0.000016081647,0.00015910344,0.00003908744,0.0010299231],"genre_scores_gemma":[0.9970385,0.0007135606,0.0015400803,0.000056168243,0.00002052425,0.000010598443,0.00024398373,0.0000056924146,0.00037097037],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991536,0.0000124864,0.000007885663,0.000019987416,0.000023504595,0.00002078753],"domain_scores_gemma":[0.9998498,0.000025219619,0.00005280039,0.000012002949,0.000027310265,0.000032911412],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026215808,0.00025694323,0.00016578218,0.00043347903,0.00011458298,0.00040912864,0.00013769152,0.00029370727,0.0005442299],"category_scores_gemma":[0.00048618147,0.00015111698,0.0001349938,0.00024072571,0.00020645298,0.00018262293,0.00017960022,0.0002900093,0.00040145734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032942535,0.000026230551,0.008823863,0.00002003713,0.000008513711,0.0003191579,0.000047623074,0.00003877578,0.9855666,0.0001561998,0.00007115761,0.004592441],"study_design_scores_gemma":[0.000031288513,0.00036572915,0.44280759,0.00001927881,0.000049508188,0.0059075616,0.00011195565,0.0029043532,0.54435605,0.0012610515,0.002169453,0.000016314816],"about_ca_topic_score_codex":0.0002884216,"about_ca_topic_score_gemma":0.0001603587,"teacher_disagreement_score":0.0005442299,"about_ca_system_score_codex":0.00018075592,"about_ca_system_score_gemma":0.0001256695,"threshold_uncertainty_score":0.0018206239},"labels":[],"label_agreement":null},{"id":"W2055137430","doi":"10.1186/1471-2407-12-229","title":"The heat shock protein-90 co-chaperone, Cyclophilin 40, promotes ALK-positive, anaplastic large cell lymphoma viability and its expression is regulated by the NPM-ALK oncoprotein","year":2012,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Alberta Innovates; Alberta Innovates - Health Solutions; University of Alberta; Alberta Cancer Foundation","keywords":"Anaplastic lymphoma kinase; Anaplastic large-cell lymphoma; Cancer research; Hsp90 inhibitor; JUNB; Heat shock protein; Hsp90; Biology; Tyrosine kinase; Crizotinib; Fusion protein; Molecular biology; Chemistry; Cell biology; Transcription factor; Signal transduction; Lymphoma; Biochemistry; Medicine; Gene; Immunology","score_opus":0.009458471611470566,"score_gpt":0.25368040090033894,"score_spread":0.24422192928886838,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055137430","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99634784,0.0016112573,0.0005597109,0.00008100288,0.000016776497,0.000011805202,0.00020194009,0.00005889438,0.0011107612],"genre_scores_gemma":[0.9969116,0.0005317015,0.000309317,0.00003464749,0.0000063999983,0.000019421772,0.0002978897,0.000007185028,0.0018819354],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999187,0.000010021997,0.0000054019265,0.000011791761,0.000032129625,0.000021914262],"domain_scores_gemma":[0.9999372,0.000009074705,0.00001856526,0.0000048952916,0.000009717288,0.000020422218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000052669602,0.0001479953,0.00013256173,0.00016523583,0.00012340458,0.00021984077,0.00007256866,0.00013715832,0.001018386],"category_scores_gemma":[0.000058515823,0.0000724382,0.00015665877,0.00010942446,0.0001361495,0.000117668606,0.00015026321,0.00030248938,0.0003128472],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058008998,0.000018545194,0.00027627344,0.000018807026,0.0000027580168,0.000035819514,0.000009334451,0.000013362786,0.9990068,0.000026010663,0.000047959424,0.00048633027],"study_design_scores_gemma":[0.000016595051,0.00026541346,0.026388079,0.000006186911,0.000021237845,0.00028174362,0.00006875487,0.0007873783,0.96877843,0.000028372257,0.0033540467,0.0000037141172],"about_ca_topic_score_codex":0.00039085175,"about_ca_topic_score_gemma":0.00079302717,"teacher_disagreement_score":0.001018386,"about_ca_system_score_codex":0.00018265114,"about_ca_system_score_gemma":0.00011032865,"threshold_uncertainty_score":0.0034068227},"labels":[],"label_agreement":null},{"id":"W2055177182","doi":"10.1002/jcb.10722","title":"Activation of calcineurin expression in ischemia‐reperfused rat heart and in human ischemic myocardium","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Calpain; Calcineurin; Ischemia; Western blot; Proteolysis; Internal medicine; Immunostaining; Sarcolemma; Extracellular; Biology; Endocrinology; Myocyte; Immunohistochemistry; Medicine; Cell biology; Biochemistry; Transplantation; Enzyme","score_opus":0.008370011762515615,"score_gpt":0.24399334033860232,"score_spread":0.2356233285760867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055177182","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879495,0.009350408,0.0008565144,0.00006204685,0.00003718367,0.000026669532,0.00021518974,0.000041334002,0.0014610708],"genre_scores_gemma":[0.99207425,0.003565127,0.0011254833,0.00004756166,0.00003860122,0.00004888306,0.0008828955,0.000007640851,0.002209706],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991477,0.00001155414,0.000006443309,0.000021631497,0.000023841825,0.000021752205],"domain_scores_gemma":[0.999902,0.00001736873,0.00002906355,0.000011983446,0.000011896814,0.00002762723],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024966968,0.00026618433,0.00020426624,0.00046577372,0.00013677865,0.00026974443,0.00011582874,0.000289323,0.0021442224],"category_scores_gemma":[0.00018111132,0.00011690262,0.00018108317,0.00031796197,0.00028216318,0.0001550727,0.00010609267,0.00033834565,0.00030919383],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026136855,0.00004000041,0.001236418,0.00008493523,0.000012185958,0.00027837534,0.00007404651,0.00001772509,0.9962662,0.000060407456,0.000038125327,0.0016301508],"study_design_scores_gemma":[0.00010351371,0.002080017,0.14766654,0.0000333813,0.00014494329,0.0049846265,0.00028258393,0.00048190227,0.83931327,0.00017906899,0.004715152,0.000014860631],"about_ca_topic_score_codex":0.0005845307,"about_ca_topic_score_gemma":0.0005320614,"teacher_disagreement_score":0.0021442224,"about_ca_system_score_codex":0.00017959885,"about_ca_system_score_gemma":0.00014527986,"threshold_uncertainty_score":0.007173121},"labels":[],"label_agreement":null},{"id":"W2055407404","doi":"10.1016/j.yexcr.2008.07.010","title":"Glycogen synthase kinase 3β regulation of nuclear factor of activated T-cells isoform c1 in the vascular smooth muscle cell response to injury","year":2008,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Heart and Stroke Foundation of Canada","keywords":"Biology; GSK-3; Gene isoform; Glycogen synthase; Cell biology; Glycogen; Vascular smooth muscle; Kinase; Biochemistry; Phosphorylation; Endocrinology; Gene; Smooth muscle","score_opus":0.03801537977364563,"score_gpt":0.32558074584669716,"score_spread":0.28756536607305155,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055407404","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957086,0.0014730697,0.0006334349,0.00028555928,0.00006960757,0.000015157183,0.0002385325,0.000030687166,0.0015454554],"genre_scores_gemma":[0.99623317,0.00073074055,0.00029841406,0.00008127295,0.00001773145,0.00003171203,0.00025604723,0.00001471741,0.0023362099],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998253,0.00003157439,0.000009981382,0.000030274232,0.000026511632,0.000076372766],"domain_scores_gemma":[0.99982905,0.000014795372,0.00003227707,0.000017717979,0.000034953395,0.00007123097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002705862,0.00031196378,0.00023040168,0.0003992833,0.000398092,0.00039812486,0.00020530973,0.00027394883,0.0014926582],"category_scores_gemma":[0.00021194658,0.00017252484,0.0003106194,0.00022328136,0.00041751037,0.00020987129,0.00025349087,0.0006114732,0.00034544696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012044306,0.000042852134,0.00068738055,0.000039250383,0.000008125011,0.000112624286,0.000060078604,0.00007461054,0.99622345,0.00032698686,0.00018002905,0.0010401706],"study_design_scores_gemma":[0.0002655981,0.0004876964,0.11688597,0.000030819334,0.000055847868,0.0005155863,0.0005821113,0.0021165574,0.87466776,0.0006134051,0.0037549164,0.000023743423],"about_ca_topic_score_codex":0.003091455,"about_ca_topic_score_gemma":0.0031773036,"teacher_disagreement_score":0.003091455,"about_ca_system_score_codex":0.00070277456,"about_ca_system_score_gemma":0.00053859485,"threshold_uncertainty_score":0.006146908},"labels":[],"label_agreement":null},{"id":"W2055460844","doi":"10.1038/ncomms4303","title":"IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling","year":2014,"lang":"en","type":"article","venue":"Nature Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":143,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"National Natural Science Foundation of China","keywords":"IRF8; Pressure overload; Innate immune system; Calcineurin; Muscle hypertrophy; Immune system; Cell biology; Biology; Immunology; Medicine; Internal medicine; Transcription factor; Endocrinology; Cardiac hypertrophy; Gene; Biochemistry; Transplantation","score_opus":0.017358877613164476,"score_gpt":0.2839505387672409,"score_spread":0.26659166115407645,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055460844","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910227,0.0028555142,0.0027647892,0.00036164394,0.00008487051,0.000024790948,0.00016077019,0.00023844166,0.002486467],"genre_scores_gemma":[0.99343675,0.0012073196,0.0022949683,0.00010431539,0.00003996433,0.000026741962,0.00021050175,0.00003450263,0.0026449536],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986935,0.000025717682,0.000012353761,0.000021370906,0.00003597494,0.000035158006],"domain_scores_gemma":[0.99989104,0.000016298598,0.00003465084,0.000015701946,0.000012127784,0.000030098423],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021044658,0.00034863033,0.00027337557,0.0002509881,0.00013922247,0.00023663526,0.00031165074,0.00033584685,0.0015717347],"category_scores_gemma":[0.000120195706,0.00012763607,0.00026175022,0.00007662774,0.00026174623,0.00016735903,0.00016042936,0.0007216092,0.0003205234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026554,0.0000659235,0.00015793082,0.00003655999,0.000007099661,0.000033743818,0.000007871413,0.00004621572,0.99659795,0.000111011,0.000060878225,0.002609269],"study_design_scores_gemma":[0.00011319618,0.0010100523,0.0040751253,0.000012618058,0.000032465723,0.00045634972,0.000026884272,0.00093743653,0.9886529,0.00016758598,0.0045086537,0.000006834955],"about_ca_topic_score_codex":0.00017972391,"about_ca_topic_score_gemma":0.00038820188,"teacher_disagreement_score":0.0015717347,"about_ca_system_score_codex":0.00014991185,"about_ca_system_score_gemma":0.00015643591,"threshold_uncertainty_score":0.0052580237},"labels":[],"label_agreement":null},{"id":"W2055982830","doi":"10.1007/s00018-009-0223-z","title":"LIM domain only 4 protein promotes granulocyte colony-stimulating factor-induced signaling in neurons","year":2009,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; Heart and Stroke Foundation; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"STAT3; Histone deacetylase; Neuroprotection; Cell biology; HDAC1; Signal transduction; Cancer research; Histone; Biology; Chemistry; Neuroscience; Gene; Biochemistry","score_opus":0.019893090155248906,"score_gpt":0.26172177202829244,"score_spread":0.24182868187304354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055982830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99567956,0.00068290986,0.0011871565,0.00021078592,0.00003064778,0.000014969206,0.00028836614,0.000066275075,0.0018394222],"genre_scores_gemma":[0.9929536,0.00044666865,0.0019955246,0.00009496221,0.0000149444195,0.000043201602,0.00082001556,0.000031643733,0.0035995313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998666,0.000022527815,0.000011076291,0.000014897177,0.000030698982,0.00005407348],"domain_scores_gemma":[0.9998652,0.00003007297,0.000018121738,0.00002082776,0.000013274619,0.000052546315],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020054205,0.0003412181,0.0002820857,0.0004380293,0.0003192891,0.0004360429,0.00040090678,0.0003298856,0.0016223057],"category_scores_gemma":[0.00021825766,0.00016518164,0.00047078446,0.00020669504,0.00036810857,0.0002542526,0.0004920958,0.0009207421,0.00046752073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004574174,0.000050804163,0.0002155748,0.0000356975,0.000009778121,0.00014849976,0.0000132350715,0.00008437652,0.99779284,0.00027656945,0.00010006247,0.00081508013],"study_design_scores_gemma":[0.00007214205,0.00015116813,0.005790329,0.0000073373885,0.000019519477,0.00027329792,0.00005950451,0.0009762126,0.990612,0.00023258885,0.0018017943,0.0000041375356],"about_ca_topic_score_codex":0.0011160471,"about_ca_topic_score_gemma":0.0020652963,"teacher_disagreement_score":0.0016223057,"about_ca_system_score_codex":0.00082950504,"about_ca_system_score_gemma":0.0005142635,"threshold_uncertainty_score":0.0060185194},"labels":[],"label_agreement":null},{"id":"W2055994404","doi":"10.1111/jcmm.12082","title":"Essential role of Pin1 <i>via </i><scp>STAT</scp>3 signalling and mitochondria‐dependent pathways in restenosis in type 2 diabetes","year":2013,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McMaster University","keywords":"Neointima; Neointimal hyperplasia; Cell cycle; Vascular smooth muscle; Cancer research; Cell biology; Apoptosis; Restenosis; Biology; Internal medicine; Endocrinology; Chemistry; Medicine; Biochemistry","score_opus":0.005558946542873801,"score_gpt":0.20885708609021458,"score_spread":0.20329813954734077,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2055994404","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865454,0.006199466,0.0027659691,0.00046305917,0.00008780508,0.000045346616,0.0012621932,0.00020202072,0.0024287105],"genre_scores_gemma":[0.9945439,0.0023232356,0.00067617005,0.00014305486,0.000027646838,0.000051214643,0.0008991661,0.000017242506,0.0013183734],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991715,0.000013012819,0.000006589295,0.000015035654,0.000016523485,0.00003163112],"domain_scores_gemma":[0.99994004,0.000004184554,0.00002157806,0.000003896998,0.0000054738725,0.000024825704],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013133013,0.00040887852,0.00026627647,0.00029887742,0.00026711024,0.0003062644,0.0001269245,0.00025858244,0.00161946],"category_scores_gemma":[0.00006260737,0.00015238061,0.00033252785,0.00021303314,0.00025640705,0.0002355141,0.0002220081,0.00077460083,0.00029509296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014987134,0.00008556803,0.0008673097,0.00018650728,0.000018304465,0.00022705826,0.000027794897,0.00016529115,0.9928652,0.0003665295,0.00033218603,0.003359564],"study_design_scores_gemma":[0.00037033073,0.0016275628,0.08213579,0.00006247699,0.00015462199,0.0015017517,0.00020026087,0.003722897,0.8979322,0.00082961225,0.011415647,0.000046810062],"about_ca_topic_score_codex":0.00049674,"about_ca_topic_score_gemma":0.00063577446,"teacher_disagreement_score":0.00161946,"about_ca_system_score_codex":0.00032907113,"about_ca_system_score_gemma":0.00031535872,"threshold_uncertainty_score":0.005417645},"labels":[],"label_agreement":null},{"id":"W2056581444","doi":"10.1006/bbrc.2001.4471","title":"Loss of Calcineurin from the Medial Preoptic Area of Primiparous Rats","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Credit Valley Hospital","funders":"","keywords":"Calcineurin; Endocrinology; Internal medicine; Hippocampus; Biology; Amygdala; Phosphatase; Western blot; Hypothalamus; Neuroscience; Cell biology; Medicine; Phosphorylation","score_opus":0.0906824049385707,"score_gpt":0.36639957365545067,"score_spread":0.27571716871687996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056581444","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971585,0.00055633474,0.0011297921,0.00024263772,0.00006121267,0.000010059999,0.00021389173,0.000043793385,0.00058383215],"genre_scores_gemma":[0.9889769,0.0010435097,0.0023220086,0.00024956468,0.000055243207,0.00007654605,0.00044100534,0.00012382845,0.0067113466],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99972457,0.000020497748,0.000015127128,0.000078012315,0.00006970719,0.00009206924],"domain_scores_gemma":[0.9987999,0.0001387278,0.00030985798,0.00017185495,0.00006399723,0.0005157781],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021739119,0.00053238636,0.00060589204,0.0010406337,0.0006176535,0.00054255046,0.0005641991,0.00050754484,0.0029493342],"category_scores_gemma":[0.0006363222,0.0006717158,0.0002841815,0.00022854873,0.0015091383,0.0006282071,0.00074129255,0.0017198315,0.00042113246],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015139357,0.0000637443,0.0012053406,0.00003113925,0.000011918348,0.00035733145,0.0000813186,0.000033742235,0.9936597,0.00030780595,0.000077452285,0.0026565269],"study_design_scores_gemma":[0.00024603924,0.001625227,0.063484795,0.00004388703,0.00009514959,0.0033757498,0.0010629975,0.0011651486,0.9235823,0.0011028007,0.0041593076,0.00005658832],"about_ca_topic_score_codex":0.002382057,"about_ca_topic_score_gemma":0.003795182,"teacher_disagreement_score":0.0029493342,"about_ca_system_score_codex":0.00063522975,"about_ca_system_score_gemma":0.0008025041,"threshold_uncertainty_score":0.009866476},"labels":[],"label_agreement":null},{"id":"W2056894517","doi":"10.1006/jmcc.2000.1150","title":"A Farnesyltransferase Inhibitor Attenuates Cardiac Myocyte Hypertrophy and Gene Expression","year":2000,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Endocrinology; Internal medicine; Farnesyltransferase; Farnesyltransferase inhibitor; Endothelin 1; Norepinephrine; Myocyte; Biology; MEK inhibitor; MAPK/ERK pathway; Chemistry; Kinase; Medicine; Prenylation; Cell biology; Biochemistry; Receptor; Dopamine","score_opus":0.004978448003956132,"score_gpt":0.19612134755693544,"score_spread":0.1911428995529793,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056894517","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867208,0.00313189,0.003978595,0.0008522851,0.00042898158,0.00013352354,0.0010362121,0.0003797899,0.0033379484],"genre_scores_gemma":[0.9860001,0.0022125808,0.0032998403,0.00029294644,0.00017878244,0.0001899597,0.0011798375,0.00008665098,0.006559215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996057,0.000058082594,0.000043488995,0.00007350202,0.00006389457,0.00015538727],"domain_scores_gemma":[0.99948955,0.00011297973,0.000086069136,0.00006416264,0.00003512893,0.00021216433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000498073,0.0009985836,0.0013301533,0.0006200431,0.0005644869,0.0007233505,0.00076183525,0.00087541103,0.0034345686],"category_scores_gemma":[0.00043462016,0.0005861505,0.0006178216,0.0003963061,0.0009843253,0.00065759756,0.0003315478,0.002457667,0.00073402456],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004863028,0.00058823085,0.00012686523,0.000087491055,0.00004352163,0.00009917554,0.000035829635,0.00020522052,0.9909793,0.0003170858,0.00028024035,0.002374188],"study_design_scores_gemma":[0.0011005442,0.0031037275,0.002613724,0.000014144057,0.00010439418,0.00018036285,0.000094307965,0.0012120053,0.9893652,0.00013219737,0.0020612874,0.000018117198],"about_ca_topic_score_codex":0.0015021389,"about_ca_topic_score_gemma":0.0034580706,"teacher_disagreement_score":0.0034345686,"about_ca_system_score_codex":0.00071616896,"about_ca_system_score_gemma":0.001338609,"threshold_uncertainty_score":0.011489749},"labels":[],"label_agreement":null},{"id":"W2057577993","doi":"10.1152/ajpcell.00196.2005","title":"Calcineurin-NFAT signaling, together with GABP and peroxisome PGC-1α, drives utrophin gene expression at the neuromuscular junction","year":2005,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"NFAT; Utrophin; Calcineurin; Synaptogenesis; Cell biology; Biology; Molecular biology; Transcription factor; Chemistry; Skeletal muscle; Dystrophin; Gene; Biochemistry; Endocrinology; Internal medicine; Transplantation; Medicine","score_opus":0.004795730394177328,"score_gpt":0.21269113487519786,"score_spread":0.20789540448102053,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057577993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99458534,0.0010404962,0.0022392643,0.00010372313,0.000032293763,0.00003744667,0.00036852807,0.0000860507,0.0015069012],"genre_scores_gemma":[0.98875135,0.00070861366,0.0045986394,0.0000502868,0.000010107724,0.00006498936,0.00055062165,0.000048361264,0.005216958],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997489,0.00003391872,0.000029313253,0.00008196953,0.00006131259,0.000044702745],"domain_scores_gemma":[0.9997665,0.00003723348,0.00006747818,0.000029306922,0.000018128194,0.000081339356],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018951167,0.0005469937,0.00029186605,0.000287163,0.00023265755,0.00027035255,0.0003644721,0.0003850576,0.001008334],"category_scores_gemma":[0.00013101356,0.00026980514,0.0003743689,0.000194859,0.00039027355,0.00023023304,0.0003414913,0.0007719826,0.000395444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039971277,0.000009609826,0.00009981481,0.000016374295,0.0000025112136,0.000025939802,0.000009125773,0.00002938633,0.99942845,0.00006305804,0.000007282532,0.000268458],"study_design_scores_gemma":[0.000016608159,0.00012503167,0.0032696486,0.0000073857486,0.000013705948,0.0001262813,0.000023974255,0.0011464369,0.99391395,0.000033138655,0.0013203326,0.0000034273626],"about_ca_topic_score_codex":0.0018592345,"about_ca_topic_score_gemma":0.005066537,"teacher_disagreement_score":0.0018592345,"about_ca_system_score_codex":0.00069819845,"about_ca_system_score_gemma":0.00038981135,"threshold_uncertainty_score":0.0050657988},"labels":[],"label_agreement":null},{"id":"W2057634274","doi":"10.4161/psb.26115","title":"ScFKBP12 bridges rapamycin and AtTOR in<i>Arabidopsis</i>","year":2013,"lang":"en","type":"article","venue":"Plant Signaling & Behavior","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute","funders":"","keywords":"FKBP; Biology; Yeast; Arabidopsis; Saccharomyces cerevisiae; Cell biology; Function (biology); TOR signaling; Sirolimus; Prolyl isomerase; Isomerase; Peptidylprolyl isomerase; Biochemistry; PIN1; Gene; Mutant","score_opus":0.014340338981199286,"score_gpt":0.23532438404685554,"score_spread":0.22098404506565625,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057634274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9497342,0.0045624874,0.019852564,0.00086381,0.00044429654,0.00013664358,0.00638349,0.002108813,0.015913747],"genre_scores_gemma":[0.9526174,0.0009909616,0.008462397,0.00031374895,0.000022945773,0.000052037776,0.0061513893,0.0001803715,0.031208724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99982363,0.000016539312,0.000014690574,0.00004579988,0.00006353501,0.00003584884],"domain_scores_gemma":[0.9999391,0.000005729756,0.000014800473,0.00000831304,0.0000073448286,0.000024670384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010112501,0.00041037038,0.0002609394,0.00030786105,0.00033787955,0.00033464655,0.00049885246,0.0004105101,0.005671871],"category_scores_gemma":[0.00008148583,0.0002224872,0.00033545325,0.0002589152,0.00020030356,0.0002083663,0.00034786426,0.00081383955,0.0030300783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009510812,0.00001610171,0.00020844667,0.000044210108,0.0000065242007,0.00011758349,0.00000804848,0.00005048938,0.9954679,0.0001981492,0.0004879327,0.0032995525],"study_design_scores_gemma":[0.0000166104,0.000055201024,0.0044511887,0.000007462863,0.000015064676,0.00045917646,0.00001627987,0.00061460386,0.970595,0.000053623065,0.02370866,0.00000715769],"about_ca_topic_score_codex":0.003026013,"about_ca_topic_score_gemma":0.0043111434,"teacher_disagreement_score":0.005671871,"about_ca_system_score_codex":0.000663079,"about_ca_system_score_gemma":0.0002551144,"threshold_uncertainty_score":0.018974245},"labels":[],"label_agreement":null},{"id":"W2057784382","doi":"10.1016/s0014-5793(01)03096-4","title":"Mechanism of Kex2p inhibition by its proregion","year":2001,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Pichia pastoris; Chemistry; Recombinant DNA; Chaperone (clinical); Proteases; Biochemistry; Cell biology; Secretion; Enzyme; Biology; Gene","score_opus":0.01047822458181149,"score_gpt":0.2215664946662519,"score_spread":0.2110882700844404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057784382","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9753337,0.012579732,0.009303201,0.00014561087,0.00003075263,0.000040077914,0.00027469764,0.00007087052,0.0022214204],"genre_scores_gemma":[0.9933761,0.0024942225,0.0019848703,0.000054048585,0.0000124836015,0.000030369178,0.00025452353,0.000009904542,0.0017835312],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998847,0.000024806344,0.000010057503,0.000027723137,0.000027264401,0.000025439285],"domain_scores_gemma":[0.999931,0.000020827105,0.000019500558,0.0000065923655,0.000011888233,0.000010147484],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016471076,0.0005097399,0.0003598313,0.00009490104,0.00010098374,0.00032017005,0.00028872397,0.0003102438,0.0006730279],"category_scores_gemma":[0.00012626214,0.00012579921,0.00025345682,0.00006431611,0.00017899196,0.00025431372,0.00015642859,0.00041399317,0.00042421278],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016825895,0.000013997456,0.0002304708,0.000057663707,0.000010418805,0.00013901282,0.000013068096,0.00016496677,0.9978612,0.00015957319,0.00002848583,0.0011528289],"study_design_scores_gemma":[0.000010997252,0.00012841153,0.0013315892,0.0000035605735,0.0000096322065,0.0004913189,0.000007608904,0.0008221259,0.9957639,0.000045593515,0.0013818298,0.00000335634],"about_ca_topic_score_codex":0.00018798285,"about_ca_topic_score_gemma":0.0001246088,"teacher_disagreement_score":0.0006730279,"about_ca_system_score_codex":0.00019432392,"about_ca_system_score_gemma":0.00010119129,"threshold_uncertainty_score":0.0022515059},"labels":[],"label_agreement":null},{"id":"W2057910472","doi":"10.1021/jm301755q","title":"Novel Inhibitors of Protein Arginine Deiminase with Potential Activity in Multiple Sclerosis Animal Model","year":2013,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto; University Health Network","funders":"Hospital for Sick Children; University Health Network","keywords":"Citrullination; Chemistry; Citrulline; Arginine; Myelin basic protein; In silico; Biochemistry; Enzyme; Multiple sclerosis; In vivo; Small molecule; Arginine deiminase; Myelin; Central nervous system; Amino acid; Immunology; Biology; Neuroscience","score_opus":0.020126626548476554,"score_gpt":0.2201589034800439,"score_spread":0.20003227693156736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2057910472","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96045685,0.022356667,0.008217588,0.0003200756,0.00011241304,0.0004298544,0.0011432326,0.0003237596,0.0066395723],"genre_scores_gemma":[0.96929204,0.01636522,0.006403208,0.00025887153,0.000033245677,0.0003103678,0.0013545543,0.000023392346,0.005959036],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999602,0.0000073380374,0.00000279792,0.000007843653,0.000008484434,0.000013390561],"domain_scores_gemma":[0.99996686,0.0000053515146,0.000009341889,0.0000022323584,0.0000057188768,0.000010506253],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014938417,0.00047917254,0.00046294215,0.00038431058,0.00011924374,0.00017811023,0.00033017917,0.0002554576,0.0012056086],"category_scores_gemma":[0.000069465976,0.00013671593,0.00025255512,0.00025177086,0.00012116892,0.00016872112,0.000122533,0.00046187808,0.000270433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011977359,0.0010126248,0.00036665786,0.00057151954,0.00009491738,0.00041176355,0.000040385225,0.0016978714,0.95692956,0.00067941897,0.0008096264,0.036187857],"study_design_scores_gemma":[0.0014046658,0.014840976,0.0050024893,0.00007965733,0.00027248924,0.0010668508,0.000040222036,0.004441243,0.948406,0.00034485015,0.024059499,0.00004113537],"about_ca_topic_score_codex":0.00039033586,"about_ca_topic_score_gemma":0.0011133251,"teacher_disagreement_score":0.0012056086,"about_ca_system_score_codex":0.00019627452,"about_ca_system_score_gemma":0.00017370936,"threshold_uncertainty_score":0.004033208},"labels":[],"label_agreement":null},{"id":"W2058609749","doi":"10.1074/jbc.c500353200","title":"Regulation of the Transcriptional Activity of c-Fos by ERK","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":278,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institutes of Health","keywords":"Transactivation; PIN1; MAPK/ERK pathway; Phosphorylation; Transcription factor; Kinase; Transcription (linguistics); c-Fos; Cell biology; Prolyl isomerase; Chemistry; Protein kinase A; Transcriptional regulation; Signal transduction; Biology; Gene; Gene expression; Biochemistry; Isomerase","score_opus":0.017598596267547083,"score_gpt":0.2441724516154613,"score_spread":0.22657385534791422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058609749","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97892994,0.0056136316,0.0070843445,0.00019954935,0.000091370806,0.00009018272,0.0008790578,0.00010158796,0.0070104017],"genre_scores_gemma":[0.985053,0.002797389,0.004911364,0.000106461666,0.000025054069,0.000108267486,0.0014144431,0.000018522685,0.0055655325],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998356,0.000018530953,0.000010308944,0.000040246723,0.000037613878,0.000057639776],"domain_scores_gemma":[0.9999267,0.000014655256,0.000014849107,0.0000071465784,0.000015535217,0.000021094875],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012669656,0.00036928375,0.00018024562,0.00031790102,0.000317241,0.00032731428,0.00021901523,0.0001616979,0.003251595],"category_scores_gemma":[0.00014328337,0.0001389633,0.00024466164,0.00018230038,0.0001842174,0.00023499998,0.0003033526,0.0005603715,0.00064971927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020240956,0.000042336163,0.00014010076,0.00009923741,0.0000054552734,0.000041941214,0.000015930449,0.000055066266,0.99573404,0.00028521736,0.000084299965,0.0032940104],"study_design_scores_gemma":[0.000023220238,0.00015524356,0.00505334,0.000010679409,0.0000069046205,0.0002891869,0.000031706237,0.0011868495,0.98842525,0.00011787533,0.004692255,0.000007498469],"about_ca_topic_score_codex":0.00029259603,"about_ca_topic_score_gemma":0.000426567,"teacher_disagreement_score":0.003251595,"about_ca_system_score_codex":0.00033737873,"about_ca_system_score_gemma":0.00021310648,"threshold_uncertainty_score":0.010877609},"labels":[],"label_agreement":null},{"id":"W2058851167","doi":"10.1016/j.saa.2012.07.105","title":"The acidic pH-induced structural changes in Pin1 as revealed by spectral methodologies","year":2012,"lang":"en","type":"article","venue":"Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; Key Technologies Research and Development Program; Sichuan University; Université Laval","keywords":"Chemistry; Fluorescence; Photochemistry; Circular dichroism; Biophysics; Chromophore; Intermolecular force; Denaturation (fissile materials); Crystallography; Nuclear chemistry; Organic chemistry; Molecule; Biology","score_opus":0.017688661529116016,"score_gpt":0.3048284622945534,"score_spread":0.2871398007654374,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2058851167","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9808655,0.0013378485,0.013086227,0.00037671477,0.000052312615,0.000024770186,0.00031585695,0.00006692519,0.0038737927],"genre_scores_gemma":[0.9955048,0.0005601022,0.0023104206,0.000119522316,0.000009247457,0.00002621711,0.00021374217,0.000015589607,0.0012404334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992,0.000015450116,0.000003212631,0.000016974684,0.000021488831,0.000022938091],"domain_scores_gemma":[0.99988353,0.000038285914,0.000036162848,0.000010797998,0.00001493457,0.00001640999],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017095199,0.00021236876,0.00007382251,0.00013222618,0.0002038349,0.00016504861,0.00023999444,0.00024545137,0.0025167214],"category_scores_gemma":[0.0002565643,0.0001817429,0.00013409727,0.00014607706,0.00032911316,0.00031508767,0.00022619162,0.00088027987,0.00025118727],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007920771,0.000005307077,0.00008568073,0.000020296957,0.000003367739,0.000031191546,0.000017504797,0.000056610497,0.9986066,0.00018763448,0.000031005293,0.0008757585],"study_design_scores_gemma":[0.000004590672,0.000047711474,0.0030089014,0.000002685533,0.000003993461,0.0001622095,0.00002871171,0.00047308748,0.99530256,0.000109664674,0.0008513106,0.000004456813],"about_ca_topic_score_codex":0.0002728699,"about_ca_topic_score_gemma":0.0003348278,"teacher_disagreement_score":0.0025167214,"about_ca_system_score_codex":0.00018922314,"about_ca_system_score_gemma":0.000092330054,"threshold_uncertainty_score":0.008419275},"labels":[],"label_agreement":null},{"id":"W2060140423","doi":"10.3892/ijo.2013.1797","title":"FKBP10/FKBP65 expression in high-grade ovarian serous carcinoma and its association with patient outcome","year":2013,"lang":"en","type":"article","venue":"International Journal of Oncology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; McGill University; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"Biology; Serous fluid; Staining; Immunohistochemistry; Stromal cell; Pathology; Ovarian carcinoma; Serous carcinoma; Tissue microarray; Cell; Cancer research; Molecular biology; Ovarian cancer; Cancer; Genetics; Immunology; Medicine","score_opus":0.012976009052428714,"score_gpt":0.27753390182537196,"score_spread":0.2645578927729432,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2060140423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99931693,0.0002581984,0.00004855797,0.000014191693,0.0000029874143,0.0000020661587,0.00012232435,0.0000037116904,0.000231161],"genre_scores_gemma":[0.99970526,0.000070048314,0.000020760854,0.000004716153,0.0000027698804,0.0000019008301,0.00009882353,8.340247e-7,0.00009500966],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99986815,0.00002272503,0.000015501735,0.000029911398,0.000023709208,0.000039993818],"domain_scores_gemma":[0.99943084,0.00010269311,0.0002463038,0.000034609333,0.0000508029,0.00013479344],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022944524,0.00014607428,0.00019257606,0.00053182105,0.0002535837,0.00038781296,0.0001411679,0.00031301458,0.0011682955],"category_scores_gemma":[0.00077010895,0.00009036807,0.00021146213,0.00056066026,0.0002451548,0.00018215581,0.00024702694,0.00029694632,0.00021183243],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047391324,0.000024195979,0.9940724,0.00002034923,0.000032592583,0.0004488647,0.00005891177,0.000052862335,0.002739993,0.000012984504,0.00005145496,0.0020115534],"study_design_scores_gemma":[0.0000027955184,0.000068285546,0.9985361,0.0000033962247,0.000020137737,0.00075891,0.00006650973,0.00010327206,0.00029680567,0.000015982334,0.00012512042,0.0000026186265],"about_ca_topic_score_codex":0.0010386865,"about_ca_topic_score_gemma":0.0012126259,"teacher_disagreement_score":0.0011682955,"about_ca_system_score_codex":0.00018889559,"about_ca_system_score_gemma":0.000109161825,"threshold_uncertainty_score":0.0039082766},"labels":[],"label_agreement":null},{"id":"W2061076297","doi":"10.1021/bi6025837","title":"A Testis Specific Isoform of Endophilin B1, Endophilin B1t, Interacts Specifically with Protein Phosphatase-1cγ2 in Mouse Testis and Is Abnormally Expressed in PP1cγ Null Mice","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Gene isoform; Mutant; Wild type; Biology; Protein phosphatase 1; Cell biology; Molecular biology; Chemistry; Phosphatase; Gene; Phosphorylation; Biochemistry","score_opus":0.009738588869393583,"score_gpt":0.22424018749878882,"score_spread":0.21450159862939525,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061076297","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932185,0.002904038,0.0020889977,0.00006873552,0.000015895417,0.000012995391,0.00046718918,0.00008284709,0.0011409201],"genre_scores_gemma":[0.9889944,0.0020669329,0.001832533,0.00006946548,0.000018770488,0.00003767908,0.0017042954,0.000053749252,0.005222203],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985325,0.00001454394,0.000009449637,0.000050203325,0.00004796327,0.000024641742],"domain_scores_gemma":[0.99982184,0.000014991211,0.0000676617,0.000010304615,0.000012104161,0.00007304548],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010202483,0.00062342366,0.0002316758,0.0008596547,0.00017556452,0.00034121276,0.00020335813,0.00036974435,0.0010988514],"category_scores_gemma":[0.00010149076,0.00044877845,0.00028320242,0.00029231273,0.00023213749,0.00017249557,0.00021531103,0.00047142053,0.0005427118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033418986,0.0000038018209,0.0003482697,0.000013616973,0.000005760579,0.00009610796,0.0000058425853,0.000016234759,0.9991761,0.000030810275,0.00001798622,0.00025203312],"study_design_scores_gemma":[0.000038595073,0.00017916865,0.101661205,0.000022664715,0.00007596838,0.004527726,0.000053247786,0.0017510577,0.8884291,0.00013557417,0.003113192,0.000012510952],"about_ca_topic_score_codex":0.00060938275,"about_ca_topic_score_gemma":0.00072734896,"teacher_disagreement_score":0.0010988514,"about_ca_system_score_codex":0.0002802532,"about_ca_system_score_gemma":0.00016132876,"threshold_uncertainty_score":0.0036759973},"labels":[],"label_agreement":null},{"id":"W2061124081","doi":"10.1021/pr201196e","title":"Myelin Basic Protein Undergoes a Broader Range of Modifications in Mammals than in Lower Vertebrates","year":2012,"lang":"en","type":"article","venue":"Journal of Proteome Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"National Center for Research Resources; National Institutes of Health; University of Michigan","keywords":"Deamidation; Citrullination; Myelin basic protein; Lysine; Arginine; Acetylation; Biochemistry; Glutamine; Chemistry; Threonine; Biology; Myelin; Phosphorylation; Amino acid; Citrulline; Central nervous system; Enzyme; Serine; Neuroscience","score_opus":0.07786117251122324,"score_gpt":0.3703397400848329,"score_spread":0.2924785675736097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061124081","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98691213,0.0067151655,0.002983559,0.00005763066,0.000014920618,0.000009220598,0.000606989,0.000047186477,0.0026532284],"genre_scores_gemma":[0.9885323,0.0032018546,0.004344515,0.00008632464,0.000019744697,0.000012692101,0.0014664688,0.00002140413,0.0023145922],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998987,0.000007912122,0.000005978361,0.00004770137,0.000025645375,0.000014124077],"domain_scores_gemma":[0.9998988,0.000007042304,0.00005354757,0.000008365607,0.00001316347,0.000019120998],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000086974826,0.00024044885,0.00016394266,0.000450292,0.0002561324,0.0002955195,0.00010414509,0.0002272515,0.0010005687],"category_scores_gemma":[0.00012344224,0.00010797025,0.000228221,0.0005816588,0.00018945077,0.00024264106,0.00021886032,0.0002457225,0.00045947192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015629946,0.00001282814,0.014299823,0.00012918394,0.000040003255,0.0003386248,0.00015983122,0.00007912921,0.9703644,0.00022017366,0.000079591024,0.014120145],"study_design_scores_gemma":[0.000008946866,0.0004674169,0.7988978,0.00004886214,0.00009995071,0.006746839,0.00033273167,0.00043747827,0.1555747,0.0006095691,0.036745027,0.00003066525],"about_ca_topic_score_codex":0.0011585106,"about_ca_topic_score_gemma":0.0011882444,"teacher_disagreement_score":0.0011585106,"about_ca_system_score_codex":0.00015627473,"about_ca_system_score_gemma":0.00012696262,"threshold_uncertainty_score":0.0033472776},"labels":[],"label_agreement":null},{"id":"W2061466239","doi":"10.1523/jneurosci.6439-11.2012","title":"Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease","year":2012,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":110,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Biomedical Imaging and Bioengineering; National Eye Institute; National Institute on Aging; National Center for Research Resources; McGill University","keywords":"NFAT; Calcineurin; Neurotoxicity; Cell biology; Neuroprotection; Transcription factor; Senile plaques; Biology; Genetically modified mouse; Alzheimer's disease; Transgene; Neuroscience; Chemistry; Biochemistry; Internal medicine; Medicine; Transplantation; Disease; Gene; Toxicity","score_opus":0.036822965429990244,"score_gpt":0.26649751243786496,"score_spread":0.2296745470078747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061466239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99288297,0.002372144,0.0024551633,0.00025364646,0.0000765179,0.000047134745,0.00031063132,0.00027388032,0.0013280223],"genre_scores_gemma":[0.98783445,0.0026222863,0.002924684,0.00012200405,0.000039756847,0.00012489836,0.00057718693,0.00007131407,0.0056832493],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980515,0.00003095509,0.000023831302,0.000040756342,0.00004800906,0.00005133692],"domain_scores_gemma":[0.9998109,0.000018202367,0.000056765584,0.000021371818,0.000020370953,0.00007251323],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024817756,0.0010566366,0.0007102912,0.00058869267,0.00028501914,0.00039058394,0.00046999508,0.0007026109,0.001269859],"category_scores_gemma":[0.00017668094,0.0003490863,0.0003350076,0.0002828322,0.000549007,0.00043695356,0.00023962311,0.0014538385,0.00033995777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071111415,0.00028288364,0.000109723405,0.00007082296,0.000018788223,0.000068142326,0.000041195355,0.00009622759,0.99649495,0.00018512162,0.00007376097,0.0018474077],"study_design_scores_gemma":[0.00030071844,0.0032086088,0.003207036,0.00003890964,0.00008788439,0.00043455116,0.000078083074,0.0017823853,0.9870957,0.00033584345,0.003413695,0.000016587375],"about_ca_topic_score_codex":0.0010655654,"about_ca_topic_score_gemma":0.0016293296,"teacher_disagreement_score":0.001269859,"about_ca_system_score_codex":0.00032447113,"about_ca_system_score_gemma":0.00036640768,"threshold_uncertainty_score":0.0042480826},"labels":[],"label_agreement":null},{"id":"W2061795524","doi":"10.1007/s12104-009-9178-0","title":"Resonance assignments of the human AKAP13-PH domain and stabilizing DH helix","year":2009,"lang":"en","type":"article","venue":"Biomolecular NMR Assignments","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Cancer Research UK; Wellcome Trust","keywords":"Helix (gastropod); Domain (mathematical analysis); Resonance (particle physics); Chemistry; Crystallography; Physics; Biology; Ecology; Mathematics; Atomic physics","score_opus":0.010749661082304329,"score_gpt":0.2656326579355413,"score_spread":0.25488299685323695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2061795524","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98685116,0.0007163459,0.008809016,0.00019938588,0.000032618955,0.000014552957,0.00035463923,0.00006702095,0.0029552425],"genre_scores_gemma":[0.99430275,0.00030247442,0.003297303,0.00007185994,0.000008424685,0.000010503465,0.00039376185,0.000018027746,0.001594969],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999465,0.000010542412,0.0000035235923,0.0000145929525,0.000011128137,0.000013707215],"domain_scores_gemma":[0.9997656,0.00006909333,0.000021746699,0.000025949443,0.000044728564,0.00007297822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024308542,0.00015399393,0.00011322963,0.00023375508,0.00047363417,0.0001541335,0.00030026547,0.0003569247,0.0019983363],"category_scores_gemma":[0.0004999426,0.0001260634,0.000115426075,0.00029025105,0.00022674807,0.00019462395,0.00019403176,0.00035538795,0.0002751647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006019781,0.00003898819,0.0013558025,0.000087879176,0.000014450678,0.00043401096,0.0001748663,0.00064061175,0.98867255,0.0010863129,0.00052512053,0.0063673155],"study_design_scores_gemma":[0.000066591594,0.00015554538,0.016164415,0.000020207128,0.000038825943,0.0010428919,0.0002757619,0.0050891708,0.96900386,0.0009112245,0.0072065615,0.00002510672],"about_ca_topic_score_codex":0.0009488165,"about_ca_topic_score_gemma":0.0010281942,"teacher_disagreement_score":0.0019983363,"about_ca_system_score_codex":0.00029196707,"about_ca_system_score_gemma":0.00020044608,"threshold_uncertainty_score":0.006685078},"labels":[],"label_agreement":null},{"id":"W2062154725","doi":"10.1016/s1570-9639(02)00441-7","title":"Calreticulin in cardiac development and pathology","year":2002,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Alberta; Canadian Institutes of Health Research","funders":"","keywords":"Calreticulin; Calnexin; Endoplasmic reticulum; Calsequestrin; Cell biology; Biology; Regulator; Chaperone (clinical); Calcium-binding protein; Internal medicine; Pathology; Medicine; Ryanodine receptor; Genetics; Gene","score_opus":0.030196013165637633,"score_gpt":0.282037738053609,"score_spread":0.25184172488797135,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2062154725","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00030910436,0.9972832,0.00034585985,0.0003409075,0.000468992,0.0000047180315,0.00001359757,0.000011536685,0.0012219545],"genre_scores_gemma":[0.0017567631,0.99517787,0.000482807,0.0002880065,0.0003735974,0.000008944658,0.000040123545,0.0000024841993,0.0018694289],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99988496,0.000013278744,0.000020264473,0.000026524214,0.000041783645,0.000013147856],"domain_scores_gemma":[0.9997985,0.000064680986,0.0000287809,0.000011494133,0.0000689122,0.00002778713],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006365475,0.0009972516,0.0015587838,0.0015267637,0.0003946046,0.0009625321,0.0008882923,0.0013317752,0.0020871835],"category_scores_gemma":[0.000492748,0.00031865353,0.00025601522,0.002137788,0.000700044,0.0014511393,0.0006918395,0.001560739,0.0023833616],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019317103,0.00007919645,0.00023637897,0.005050946,0.00006377982,0.00051386736,0.00005108399,0.00033809725,0.0066036084,0.0036013632,0.029170398,0.9540981],"study_design_scores_gemma":[0.000039202132,0.00007371375,0.0009895663,0.0008960643,0.00008959433,0.0019463585,0.000060118327,0.0001041254,0.0021171395,0.0018505276,0.9918174,0.000016176215],"about_ca_topic_score_codex":0.0011161637,"about_ca_topic_score_gemma":0.0021037653,"teacher_disagreement_score":0.0020871835,"about_ca_system_score_codex":0.0007351594,"about_ca_system_score_gemma":0.00088276784,"threshold_uncertainty_score":0.0069823265},"labels":[],"label_agreement":null},{"id":"W2063087499","doi":"10.1042/bst20130013","title":"Resolving the functions of peptidylprolyl isomerases: insights from the mutagenesis of the nuclear FKBP25 enzyme","year":2013,"lang":"en","type":"review","venue":"Biochemical Society Transactions","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Isomerase; Peptidylprolyl isomerase; Biology; Mutagenesis; Biochemistry; Cell biology; Cis-trans-Isomerases; Mutant; Mutation; Enzyme; Gene","score_opus":0.02310451136493862,"score_gpt":0.2529416573511206,"score_spread":0.229837145986182,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063087499","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029528944,0.9976163,0.00033681767,0.0002465702,0.00013031162,0.0000029376033,0.000011143926,0.000010255531,0.0013502637],"genre_scores_gemma":[0.001483251,0.9965502,0.0005020064,0.0001624297,0.00010045126,0.000005518721,0.000027075852,0.0000025147024,0.0011666093],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.999882,0.000014038984,0.000014106571,0.00002274245,0.000052891246,0.0000141792025],"domain_scores_gemma":[0.9998266,0.00006167458,0.000027862054,0.0000075090456,0.00005051955,0.000025804238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000427797,0.0007736488,0.0007702304,0.0018799298,0.0002310716,0.000637934,0.00072279817,0.00089851534,0.0014985801],"category_scores_gemma":[0.00043898218,0.00023712082,0.00025281796,0.0017816384,0.00054356654,0.0010853946,0.00055908493,0.001337794,0.0017650931],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007237186,0.000054742784,0.00014798381,0.007865307,0.00004819075,0.0003574771,0.000066901186,0.00065517693,0.0106817195,0.0061468934,0.020332113,0.95357114],"study_design_scores_gemma":[0.000008953544,0.000055702214,0.00060685235,0.000904291,0.000039155468,0.0013744895,0.000042877815,0.000108185246,0.002373707,0.001554704,0.9929162,0.0000147845385],"about_ca_topic_score_codex":0.0011403164,"about_ca_topic_score_gemma":0.0016512327,"teacher_disagreement_score":0.0018799298,"about_ca_system_score_codex":0.0008128645,"about_ca_system_score_gemma":0.000679217,"threshold_uncertainty_score":0.005897701},"labels":[],"label_agreement":null},{"id":"W2063109204","doi":"10.1139/cjpp-2014-0520","title":"Homocysteine elicits an M1 phenotype in murine macrophages through an EMMPRIN-mediated pathway","year":2015,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Heart, Lung, and Blood Institute","keywords":"Matrix metalloproteinase; Macrophage; Nitric oxide; Chemistry; Reactive oxygen species; Hyperhomocysteinemia; Extracellular matrix; Cell culture; Elastin; Homocysteine; Cell biology; Molecular biology; Biochemistry; Endocrinology; Biology; In vitro","score_opus":0.024366884517780824,"score_gpt":0.28713098064210785,"score_spread":0.26276409612432705,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063109204","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957872,0.001712826,0.000999459,0.00007416487,0.000028959328,0.000040396753,0.00031358594,0.00004113478,0.0010022175],"genre_scores_gemma":[0.9932522,0.0010113938,0.0019803017,0.00008542873,0.000026168293,0.000091371425,0.00057983777,0.0000103040775,0.0029629397],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981076,0.000044000706,0.000022946504,0.000024848287,0.00004569563,0.000051796032],"domain_scores_gemma":[0.999908,0.000013773897,0.000025628524,0.000012086043,0.000018215474,0.00002227282],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023440765,0.0004635407,0.0002609847,0.00027711556,0.00013815076,0.00013320518,0.00013111491,0.00036448287,0.0009721168],"category_scores_gemma":[0.00006836684,0.00012507652,0.0003274997,0.00012750165,0.00015666056,0.00011549853,0.00021108845,0.00041563716,0.00040775226],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021328211,0.000034501358,0.00012881149,0.00005050997,0.000002957378,0.000060969203,0.000014900577,0.000011534002,0.9990939,0.000017205519,0.000018323146,0.0003530828],"study_design_scores_gemma":[0.000037017897,0.0013197975,0.0064473613,0.0000132151345,0.000019453166,0.00026775556,0.00003021918,0.00017214044,0.99027085,0.000026805641,0.0013913158,0.0000040126006],"about_ca_topic_score_codex":0.0002723259,"about_ca_topic_score_gemma":0.00042298323,"teacher_disagreement_score":0.0009721168,"about_ca_system_score_codex":0.0001730844,"about_ca_system_score_gemma":0.00013225077,"threshold_uncertainty_score":0.003252089},"labels":[],"label_agreement":null},{"id":"W2063311617","doi":"10.1016/s1074-7613(00)80166-1","title":"Posttranslational Regulation of IRF-4 Activity by the Immunophilin FKBP52","year":2000,"lang":"en","type":"article","venue":"Immunity","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Terry Fox Research Institute","funders":"","keywords":"Biology; Transactivation; Repressor; Enhancer; Molecular biology; Gene; Transcription factor; Biochemistry","score_opus":0.010483688551872988,"score_gpt":0.24663170318335464,"score_spread":0.23614801463148166,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063311617","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9858198,0.0042563677,0.004316888,0.0005912639,0.00012505024,0.000014621325,0.0003810287,0.00014038954,0.004354594],"genre_scores_gemma":[0.9949799,0.0006337635,0.0009681197,0.000069479924,0.000021709619,0.000009678274,0.00039978817,0.000019324152,0.0028981876],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998629,0.000025047371,0.000008264095,0.000028576937,0.000018041083,0.000057244837],"domain_scores_gemma":[0.9998932,0.000017996606,0.00002631649,0.000023007695,0.000014233608,0.000025284147],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016948943,0.00035718238,0.00023067424,0.00017662115,0.00031811933,0.00042781737,0.00025696994,0.00033005959,0.00268513],"category_scores_gemma":[0.00022234659,0.00017477732,0.00027625795,0.00010262012,0.00025648478,0.00039424605,0.00028584205,0.00060434756,0.001036772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034297575,0.000020113981,0.00035571307,0.000026920101,0.0000073332453,0.00012751708,0.000012588196,0.00008551145,0.99640083,0.00057164725,0.00016156498,0.0018872691],"study_design_scores_gemma":[0.000034101307,0.000110652945,0.024368178,0.00001085812,0.000016746693,0.00036478043,0.00006471975,0.0017478336,0.97000074,0.00041142013,0.002857027,0.000013010349],"about_ca_topic_score_codex":0.00070058124,"about_ca_topic_score_gemma":0.0012561053,"teacher_disagreement_score":0.00268513,"about_ca_system_score_codex":0.0005532409,"about_ca_system_score_gemma":0.0002022908,"threshold_uncertainty_score":0.008982658},"labels":[],"label_agreement":null},{"id":"W2064095852","doi":"10.1074/jbc.m705014200","title":"Corticosteroid-binding Globulin, a Structural Basis for Steroid Transport and Proteinase-triggered Release","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"University of Sussex","keywords":"Transcortin; Steroid; Globulin; Chemistry; Biochemistry; Endocrinology; Biology; Hormone","score_opus":0.021076191658750434,"score_gpt":0.2703219777445357,"score_spread":0.24924578608578526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064095852","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.941567,0.019733107,0.023244334,0.0023062648,0.00032531194,0.00008816089,0.00019090372,0.00048014018,0.012064849],"genre_scores_gemma":[0.99215966,0.002331763,0.002578753,0.00015975599,0.000050292998,0.000019358176,0.00012998703,0.000022940834,0.0025475477],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999409,0.00000886268,0.000003504648,0.000014945571,0.000016465958,0.000015380692],"domain_scores_gemma":[0.99994683,0.0000069588673,0.000011362406,0.0000052719192,0.0000091105885,0.000020520065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000102988924,0.00031677165,0.00022387182,0.00010256514,0.0003038377,0.00049476477,0.0003423987,0.0004524752,0.0007962468],"category_scores_gemma":[0.00015500927,0.000104349565,0.00014360603,0.00006951753,0.00051297445,0.00024122176,0.00022156844,0.00034821528,0.00044212092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012600957,0.000028889177,0.0005221625,0.00007295427,0.000012073872,0.00085128605,0.00005042491,0.0010522095,0.9838508,0.008598767,0.0003883073,0.0044461736],"study_design_scores_gemma":[0.00015333103,0.00075443316,0.01097348,0.000046217498,0.000042481715,0.0050543398,0.00020621988,0.016941348,0.9198105,0.01541621,0.03055302,0.00004852554],"about_ca_topic_score_codex":0.0006669299,"about_ca_topic_score_gemma":0.00042581596,"teacher_disagreement_score":0.0007962468,"about_ca_system_score_codex":0.00048182788,"about_ca_system_score_gemma":0.00033865304,"threshold_uncertainty_score":0.0034959316},"labels":[],"label_agreement":null},{"id":"W2064830474","doi":"10.1007/s10858-007-9172-8","title":"Hypothetical protein AF2241 from Archaeoglobus fulgidus adopts a cyclophilin-like fold","year":2007,"lang":"en","type":"article","venue":"Journal of Biomolecular NMR","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Western University","funders":"","keywords":"Chemistry; Cyclophilin; Structural genomics; Cyclophilin A; Fold (higher-order function); Computational biology; Biochemistry; Molecular biology; Protein structure; Biology; Gene; Computer science","score_opus":0.009689180815360552,"score_gpt":0.2509157987459582,"score_spread":0.24122661793059766,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2064830474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99856573,0.00033102074,0.0005219013,0.0000813814,0.000014324232,0.0000030095316,0.00013363812,0.000048147824,0.00030098474],"genre_scores_gemma":[0.99808,0.00012555347,0.00069989316,0.000053234726,0.000008960037,0.000004438151,0.0005050879,0.000008317184,0.0005144757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999709,0.000004432553,0.0000019360807,0.000008400028,0.000006514915,0.000007829501],"domain_scores_gemma":[0.9999056,0.000011550189,0.000025966396,0.000011040307,0.000011993298,0.000033837154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000067682224,0.00036836186,0.00034296617,0.00019382077,0.00033664072,0.0003415092,0.00022561997,0.00042725654,0.0005499253],"category_scores_gemma":[0.00016875747,0.000109000495,0.00023542743,0.00018513534,0.0002218367,0.00023414654,0.00015558768,0.0003483664,0.0003680317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005930556,0.000042147167,0.0062459335,0.00009377933,0.000027393977,0.00094942254,0.00007515157,0.00033992736,0.9871841,0.00039827792,0.00042649495,0.0036242788],"study_design_scores_gemma":[0.000064672684,0.0005641269,0.15081346,0.000028072885,0.00012627145,0.0068101063,0.0005551513,0.0076008937,0.82370406,0.0009659144,0.008700172,0.00006698339],"about_ca_topic_score_codex":0.00072377175,"about_ca_topic_score_gemma":0.0004785522,"teacher_disagreement_score":0.00072377175,"about_ca_system_score_codex":0.00027665173,"about_ca_system_score_gemma":0.00015513983,"threshold_uncertainty_score":0.0020073056},"labels":[],"label_agreement":null},{"id":"W2066353226","doi":"10.1016/j.febslet.2006.11.061","title":"Binding of Vac14 to neuronal nitric oxide synthase: Characterisation of a new internal PDZ‐recognition motif","year":2006,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"PDZ domain; Scaffold protein; Cell biology; Binding site; Chemistry; Protein–protein interaction; Plasma protein binding; Activator (genetics); Biochemistry; Biology; Signal transduction; Gene","score_opus":0.013370248756720214,"score_gpt":0.22731393826108467,"score_spread":0.21394368950436446,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066353226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9976743,0.00028040537,0.0015880185,0.000025114206,0.000005288851,0.0000087700455,0.000052808748,0.000007620594,0.00035780354],"genre_scores_gemma":[0.99477625,0.00017663147,0.0034035132,0.000059974107,0.0000052023065,0.000015504653,0.0004799363,0.000008131737,0.001074703],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987495,0.000017085493,0.000008564539,0.000027222097,0.000041453557,0.000030614305],"domain_scores_gemma":[0.99987125,0.0000234643,0.000026379183,0.000012108522,0.000018646864,0.000048201713],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013606864,0.0002788087,0.00036889387,0.00014153802,0.0001600248,0.00034801336,0.0002556262,0.0002874435,0.0007029709],"category_scores_gemma":[0.00020619154,0.00013246395,0.00025446698,0.000105208324,0.0001961572,0.0001261809,0.0002842246,0.00032046778,0.00029012712],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000072638526,0.000024702042,0.0006753363,0.000020066671,0.000008058303,0.00010135112,0.000015932921,0.000087580105,0.997866,0.00013230924,0.00001804865,0.0009779673],"study_design_scores_gemma":[0.000020388952,0.00016933361,0.023076484,0.000007952238,0.000019931898,0.0009966288,0.000052592546,0.0037773042,0.9695612,0.000110725654,0.0021965264,0.000010986267],"about_ca_topic_score_codex":0.00049649435,"about_ca_topic_score_gemma":0.00095582707,"teacher_disagreement_score":0.0007029709,"about_ca_system_score_codex":0.0004246249,"about_ca_system_score_gemma":0.00016160434,"threshold_uncertainty_score":0.0030808449},"labels":[],"label_agreement":null},{"id":"W2066759197","doi":"10.1016/j.neuroscience.2009.03.011","title":"Antipsychotics affect multiple calcium calmodulin dependent proteins","year":2009,"lang":"en","type":"article","venue":"Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University; London Health Sciences Centre","funders":"","keywords":"Calcineurin; Pharmacology; Haloperidol; Calmodulin; Protein kinase A; Endocrinology; Chemistry; Internal medicine; Kinase; Biology; Medicine; Biochemistry; Calcium; Transplantation; Dopamine","score_opus":0.03061643813211073,"score_gpt":0.29980919883073914,"score_spread":0.2691927606986284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2066759197","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98563695,0.0042568543,0.0019272168,0.0014019421,0.00020173944,0.000049450075,0.0004685381,0.00013108896,0.005926233],"genre_scores_gemma":[0.9929357,0.0023235767,0.001125367,0.00034034144,0.000035183708,0.000024773533,0.00017407973,0.000023671308,0.0030173108],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998665,0.000033267093,0.000009843446,0.000016450856,0.000037539998,0.000036382517],"domain_scores_gemma":[0.9998209,0.000027517393,0.00007222002,0.000013290156,0.000023980345,0.000042188687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001358129,0.0005293367,0.00040230894,0.00027906615,0.0003669602,0.000336522,0.00026814977,0.0005794835,0.0026932338],"category_scores_gemma":[0.0003764053,0.00022430599,0.0002914123,0.00019004132,0.0003039507,0.0002235472,0.0002189313,0.00065653864,0.00024697158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005815517,0.00020048146,0.0023219148,0.00014282009,0.00013847442,0.0011401676,0.000061845494,0.0004337792,0.97591966,0.0011604268,0.0010362742,0.011628661],"study_design_scores_gemma":[0.002081902,0.005369001,0.11668117,0.000105982195,0.0007815033,0.0047970335,0.0004256781,0.0068714726,0.8442599,0.0033999812,0.015127487,0.0000988053],"about_ca_topic_score_codex":0.0035380863,"about_ca_topic_score_gemma":0.00880293,"teacher_disagreement_score":0.0035380863,"about_ca_system_score_codex":0.0010556857,"about_ca_system_score_gemma":0.00042946733,"threshold_uncertainty_score":0.0090097785},"labels":[],"label_agreement":null},{"id":"W2067092931","doi":"10.1096/fj.12-213124","title":"Regulation of RCAN1 translation and its role in oxidative stress‐induced apoptosis","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Oxidative stress; Apoptosis; Translation (biology); Cell biology; Chemistry; Stress (linguistics); Biology; Biochemistry; Gene; Linguistics; Messenger RNA; Philosophy","score_opus":0.024916834146920135,"score_gpt":0.2600899491022793,"score_spread":0.23517311495535914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067092931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98740315,0.009847793,0.0013490646,0.00017306423,0.00004453788,0.000020482626,0.00021713307,0.000042359996,0.0009024191],"genre_scores_gemma":[0.99168515,0.0036905,0.0018407381,0.00007964036,0.000032266238,0.00004444913,0.00062163523,0.000016010617,0.0019895572],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999884,0.000017185659,0.000011628931,0.00003642339,0.000028483428,0.00002219828],"domain_scores_gemma":[0.9998449,0.000017756658,0.00006188038,0.000012014045,0.00003289656,0.000030591353],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016355808,0.0003775904,0.00021785744,0.00037797718,0.00034395652,0.00032117218,0.00019538759,0.00026279798,0.00058664934],"category_scores_gemma":[0.00018516925,0.000109852896,0.00028435877,0.00019882734,0.00025884513,0.0002813173,0.00017934867,0.00041272337,0.0002128841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017539003,0.000022259266,0.00079192943,0.000068030975,0.000005536877,0.00014603644,0.000047908514,0.00006127802,0.99668413,0.00017619558,0.00006048094,0.001760753],"study_design_scores_gemma":[0.000029359555,0.00017834996,0.033447098,0.000022414164,0.000030510655,0.00081441907,0.00008558215,0.0021031133,0.9576981,0.00022305443,0.0053517595,0.000016263708],"about_ca_topic_score_codex":0.0007790379,"about_ca_topic_score_gemma":0.00095398026,"teacher_disagreement_score":0.0007790379,"about_ca_system_score_codex":0.0006533446,"about_ca_system_score_gemma":0.0002687146,"threshold_uncertainty_score":0.0047403574},"labels":[],"label_agreement":null},{"id":"W2067281577","doi":"10.1021/bi700265j","title":"Peptide Binding by a Fragment of Calmodulin Composed of EF-Hands 2 and 3","year":2007,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Calmodulin; Tetramer; Peptide; Biophysics; Allosteric regulation; Crystallography; Stereochemistry; Biochemistry; Receptor; Enzyme","score_opus":0.005728296034790426,"score_gpt":0.23872032842962962,"score_spread":0.2329920323948392,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067281577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971769,0.00054055284,0.0015712691,0.000028407827,0.000010153476,0.00002010791,0.000066112065,0.000027082184,0.0005595092],"genre_scores_gemma":[0.99444073,0.00018771655,0.004030126,0.000081247585,0.000009149694,0.000023983392,0.00050505897,0.000011154505,0.0007107949],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988914,0.0000168833,0.0000063979796,0.000032371307,0.00002985682,0.000025408239],"domain_scores_gemma":[0.99992657,0.000016251617,0.00001881673,0.0000067851824,0.000007328246,0.000024230687],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010987437,0.00024463647,0.00022179651,0.00006741201,0.0001404899,0.0001548035,0.00023420302,0.00026112658,0.0009840924],"category_scores_gemma":[0.00016235528,0.00009962993,0.00017982848,0.0001010296,0.00014179495,0.00009587413,0.00018105847,0.0003880354,0.00024646914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009069379,0.000011105302,0.0002031744,0.0000134556,0.000002870584,0.000020616038,0.000005113764,0.000031041123,0.99909055,0.000014353619,0.000014100071,0.00050298276],"study_design_scores_gemma":[0.000067587716,0.0002852396,0.009810566,0.000008906578,0.00001421238,0.00041255364,0.00001692959,0.0019434036,0.9855156,0.00004201991,0.0018759082,0.0000072053003],"about_ca_topic_score_codex":0.0007056547,"about_ca_topic_score_gemma":0.0010361085,"teacher_disagreement_score":0.0009840924,"about_ca_system_score_codex":0.0003224986,"about_ca_system_score_gemma":0.00015272129,"threshold_uncertainty_score":0.0032921433},"labels":[],"label_agreement":null},{"id":"W2067747320","doi":"10.1097/01.tp.0000058811.25785.f4","title":"Combination therapy of malononitrilamide FK778 with tacrolimus on cell proliferation assays and in rats receiving renal allografts1 2","year":2003,"lang":"en","type":"article","venue":"Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Hôpital Notre-Dame","funders":"","keywords":"Tacrolimus; Medicine; Combination therapy; Transplantation; Mixed lymphocyte reaction; Peripheral blood mononuclear cell; Pharmacology; Leflunomide; Calcineurin; Kidney; T cell; Immunology; In vitro; Internal medicine; Chemistry; Immune system","score_opus":0.009142277548832728,"score_gpt":0.22481810901095153,"score_spread":0.2156758314621188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2067747320","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99451315,0.002355677,0.001385746,0.00006115668,0.00011684726,0.000053816748,0.00014591038,0.000077473356,0.0012902244],"genre_scores_gemma":[0.99373937,0.0014894756,0.0021268062,0.000037244823,0.00008253163,0.00008453596,0.000289416,0.000012884018,0.002137778],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99948967,0.00009988034,0.000036342866,0.000071503215,0.00013184847,0.00017064899],"domain_scores_gemma":[0.99963534,0.00007896174,0.00009663649,0.00004408362,0.00003788662,0.00010710292],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038704087,0.00077981956,0.0007853583,0.00078364596,0.0002435308,0.00027453998,0.00030783052,0.0003202091,0.0014103975],"category_scores_gemma":[0.00021044197,0.00019084083,0.00063149707,0.00028154402,0.0003431174,0.000326993,0.0002590849,0.0008926186,0.0003520021],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028524715,0.001141211,0.0011179417,0.00013221343,0.000042563886,0.00013941526,0.00007834521,0.00035725092,0.98416996,0.00006925913,0.000112328205,0.009787015],"study_design_scores_gemma":[0.000056035,0.011909608,0.002488963,0.0000069222733,0.00009106045,0.00015005902,0.00003393642,0.0008535567,0.9835708,0.000018616793,0.0008107898,0.000009552974],"about_ca_topic_score_codex":0.0007827519,"about_ca_topic_score_gemma":0.0014069807,"teacher_disagreement_score":0.0014103975,"about_ca_system_score_codex":0.0002684181,"about_ca_system_score_gemma":0.00038855028,"threshold_uncertainty_score":0.004718244},"labels":[],"label_agreement":null},{"id":"W2068832660","doi":"10.1038/sj.onc.1207283","title":"Functional interaction of RasGAP-binding proteins Dok-1 and Dok-2 with the Tec protein tyrosine kinase","year":2003,"lang":"en","type":"article","venue":"Oncogene","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Canadian Institutes of Health Research","keywords":"Biology; TEC; Tyrosine phosphorylation; Signal transducing adaptor protein; Tyrosine kinase; Cell biology; Protein tyrosine phosphatase; Tyrosine; Phosphorylation; Receptor tyrosine kinase; Signal transduction; Molecular biology; Biochemistry","score_opus":0.013671652993944435,"score_gpt":0.23271334308150202,"score_spread":0.21904169008755758,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2068832660","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99229795,0.003035344,0.0014308398,0.00026534608,0.000056431574,0.000007540264,0.00022702487,0.000043286243,0.0026362122],"genre_scores_gemma":[0.99446094,0.0006025046,0.0007808683,0.000057990674,0.000016521099,0.000011063767,0.0005620528,0.00001254665,0.0034955414],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978596,0.000039725288,0.000011267355,0.00002559616,0.0000618893,0.00007558382],"domain_scores_gemma":[0.9998573,0.00003249765,0.000030602816,0.000019571293,0.00001877723,0.000041136358],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020456483,0.000451176,0.0001736827,0.00030694637,0.0004722544,0.0005785495,0.00044599763,0.000380515,0.002186883],"category_scores_gemma":[0.00038721634,0.00025630463,0.00033111413,0.0001771646,0.00025916912,0.0003709352,0.0004051176,0.00067325984,0.00076082174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032826362,0.000028231983,0.0003981025,0.00005904585,0.000018084242,0.00020541625,0.000021166808,0.0001470807,0.99656576,0.001064825,0.00014065021,0.0010234074],"study_design_scores_gemma":[0.000030284751,0.0000757395,0.00953152,0.000009587504,0.000034078683,0.0013321715,0.000058189296,0.0022744974,0.98170257,0.00033299584,0.0046074125,0.000010925158],"about_ca_topic_score_codex":0.0006714573,"about_ca_topic_score_gemma":0.0011077969,"teacher_disagreement_score":0.002186883,"about_ca_system_score_codex":0.0006962349,"about_ca_system_score_gemma":0.00029449575,"threshold_uncertainty_score":0.007315874},"labels":[],"label_agreement":null},{"id":"W2069238921","doi":"10.1242/jcs.077446","title":"Localization of phosphorylated CK2α to the mitotic spindle requires the peptidyl-prolyl isomerase Pin1","year":2011,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"PIN1; Biology; Prolyl isomerase; Mitosis; Cell biology; Phosphorylation; Spindle apparatus; Peptidylprolyl isomerase; Mitotic exit; Biochemistry; Isomerase; Cell division; Enzyme; Cell","score_opus":0.018570184753790187,"score_gpt":0.24317005446981219,"score_spread":0.224599869716022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069238921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906222,0.002461104,0.0035129362,0.00017977528,0.00005072966,0.000020770585,0.00021004294,0.000052070653,0.0028902688],"genre_scores_gemma":[0.9941981,0.0008542496,0.0013113617,0.0000638554,0.00001515915,0.000013282051,0.00039229277,0.000026953532,0.0031247314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988115,0.000013880509,0.000010057841,0.000031515865,0.000025855183,0.00003751839],"domain_scores_gemma":[0.9998727,0.000014293181,0.000039204293,0.000015978518,0.000017615823,0.00004013905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012600992,0.00026953826,0.00021436835,0.00017648142,0.00024908356,0.0005260296,0.00018201258,0.00019540249,0.0017361218],"category_scores_gemma":[0.00018457642,0.00020525805,0.00015901815,0.00011631995,0.00020407254,0.00033527947,0.00024458772,0.00040427234,0.0005667355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013017937,0.000007931472,0.00016465933,0.000035268895,0.000002983367,0.00008146441,0.000011622784,0.000038132144,0.99873334,0.00014979724,0.00004682303,0.0005978713],"study_design_scores_gemma":[0.000031316908,0.000080383266,0.012022459,0.000012120144,0.000007702452,0.00058590417,0.000053817115,0.0009570786,0.9821154,0.000105833766,0.004023196,0.000004927393],"about_ca_topic_score_codex":0.00079599646,"about_ca_topic_score_gemma":0.0013736142,"teacher_disagreement_score":0.0017361218,"about_ca_system_score_codex":0.00040036143,"about_ca_system_score_gemma":0.00019629416,"threshold_uncertainty_score":0.005807936},"labels":[],"label_agreement":null},{"id":"W2070389505","doi":"10.1002/prot.22032","title":"The complex structure of calmodulin bound to a calcineurin peptide","year":2008,"lang":"en","type":"article","venue":"Proteins Structure Function and Bioinformatics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canada Research Chairs","keywords":"Calmodulin; Linker; Chemistry; Peptide; Dimer; Binding site; Stereochemistry; Protein subunit; Protein structure; Biophysics; Crystallography; Biochemistry; Enzyme; Biology","score_opus":0.01391511459948736,"score_gpt":0.22892440386889001,"score_spread":0.21500928926940266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070389505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955694,0.00071737677,0.0021674628,0.00011490184,0.000023475308,0.000015865779,0.00015173119,0.000051228453,0.0011885606],"genre_scores_gemma":[0.993504,0.00042530327,0.0030135117,0.000058925943,0.000009754503,0.000019099902,0.0011908034,0.000028741993,0.0017498345],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998534,0.00001263555,0.0000048250035,0.00004924175,0.000060964827,0.000019076037],"domain_scores_gemma":[0.9999021,0.000024319917,0.000022733604,0.0000068047034,0.00001307027,0.00003081394],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000072990835,0.0003359732,0.00033089606,0.00021919487,0.00041014398,0.00053406507,0.00067110575,0.0003934775,0.0012887181],"category_scores_gemma":[0.00031053115,0.00020570593,0.00017578094,0.00032525128,0.00036953748,0.0003586149,0.00018189599,0.0009528864,0.00018071388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044997974,0.00015914577,0.0021277037,0.00014544383,0.000081641854,0.0010986767,0.00019461865,0.0033585792,0.9870342,0.0020990241,0.0004469466,0.0028041555],"study_design_scores_gemma":[0.00043416736,0.00088681787,0.05148589,0.0000550142,0.00012487765,0.00180844,0.000352512,0.123120815,0.8013564,0.0019019399,0.018361727,0.000111452166],"about_ca_topic_score_codex":0.0037491266,"about_ca_topic_score_gemma":0.004157073,"teacher_disagreement_score":0.0037491266,"about_ca_system_score_codex":0.0011713576,"about_ca_system_score_gemma":0.00036399325,"threshold_uncertainty_score":0.008498788},"labels":[],"label_agreement":null},{"id":"W2070590783","doi":"10.1016/j.biocel.2005.08.016","title":"Troponin C/calmodulin chimeras as erythrocyte plasma membrane Ca2+-ATPase activators","year":2005,"lang":"en","type":"article","venue":"The International Journal of Biochemistry & Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Medical Research Council; Financiadora de Estudos e Projetos; Conselho Nacional de Desenvolvimento Científico e Tecnológico","keywords":"Calmodulin; Troponin C; Chimera (genetics); ATP hydrolysis; ATPase; Enzyme; Biochemistry; Plasma membrane Ca2+ ATPase; Chemistry; Cell biology; Biophysics; Biology; Troponin; Gene","score_opus":0.006555459905115123,"score_gpt":0.25526638170561405,"score_spread":0.24871092180049892,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070590783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987879,0.002259254,0.006082901,0.00029832352,0.00019143718,0.00007562513,0.00036277794,0.00021030154,0.0026403093],"genre_scores_gemma":[0.9934007,0.0005965146,0.0032863715,0.00008026931,0.000014402753,0.00002947285,0.00029359641,0.00005527319,0.0022433654],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997825,0.000039474464,0.000016974162,0.000048462178,0.000058586807,0.000054049444],"domain_scores_gemma":[0.9998752,0.00003351993,0.000023650342,0.000014429313,0.000008556802,0.00004462396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031283408,0.00021629993,0.00031677075,0.00017122834,0.00024617626,0.0005638046,0.00051103916,0.0005589011,0.0013588273],"category_scores_gemma":[0.00025209825,0.00021312578,0.00015851631,0.00018209277,0.000261029,0.00022948877,0.0002296733,0.0010790789,0.0003291825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035105884,0.000039599836,0.000070876384,0.000020064834,0.00001022564,0.00005602716,0.00001418224,0.00022169294,0.9974663,0.00062524574,0.00016606711,0.00095870503],"study_design_scores_gemma":[0.0001719238,0.00009407853,0.0006288327,0.000004800126,0.000019305106,0.00022178663,0.000015316125,0.0038651736,0.9897483,0.0001407082,0.005080939,0.000008794942],"about_ca_topic_score_codex":0.0010014934,"about_ca_topic_score_gemma":0.001871416,"teacher_disagreement_score":0.0013588273,"about_ca_system_score_codex":0.0006524256,"about_ca_system_score_gemma":0.00030104112,"threshold_uncertainty_score":0.0047337413},"labels":[],"label_agreement":null},{"id":"W2070755746","doi":"10.1074/jbc.c000096200","title":"Physical and Functional Interaction of Rabphilin-11 with Mammalian Sec13 Protein","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; National Institutes of Health","keywords":"Biology; Cell biology","score_opus":0.014899889328810489,"score_gpt":0.23858317463824963,"score_spread":0.22368328530943915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2070755746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901175,0.0029726091,0.0040865857,0.00014382962,0.000037892412,0.000025424748,0.00046335836,0.000040721116,0.0021120126],"genre_scores_gemma":[0.99061894,0.001260593,0.0022892281,0.00007336702,0.000012415021,0.00003487295,0.0018614107,0.0000129355085,0.003836203],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997845,0.000039381597,0.000021555083,0.000042309963,0.00008020678,0.000032021286],"domain_scores_gemma":[0.99991584,0.000015818428,0.000018447272,0.000015368198,0.000016573176,0.000017976326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001805766,0.00035100718,0.00020413831,0.00016579578,0.00022022218,0.0003225515,0.00017709655,0.00031509637,0.0010923903],"category_scores_gemma":[0.00020446636,0.00014597096,0.00037235412,0.00019155745,0.00019913925,0.00019911495,0.000446115,0.00038075578,0.00044033313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000717043,0.000020385776,0.00065610453,0.00006246591,0.000018010951,0.00018154402,0.000010499405,0.000047838763,0.99746215,0.00025037598,0.000053509568,0.0011654402],"study_design_scores_gemma":[0.000011015089,0.000084857886,0.01531665,0.000008562279,0.000027838625,0.00078905147,0.000029047533,0.0010612679,0.97785485,0.00009382034,0.0047160857,0.000006977061],"about_ca_topic_score_codex":0.00044846628,"about_ca_topic_score_gemma":0.00051700335,"teacher_disagreement_score":0.0010923903,"about_ca_system_score_codex":0.0003786982,"about_ca_system_score_gemma":0.00017255345,"threshold_uncertainty_score":0.00365448},"labels":[],"label_agreement":null},{"id":"W2071065554","doi":"10.1523/jneurosci.3659-10.2011","title":"EMMPRIN: A Novel Regulator of Leukocyte Transmigration into the CNS in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis","year":2011,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; National Multiple Sclerosis Society; Fondation pour la Recherche Médicale; Canadian Institutes of Health Research; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada","keywords":"Experimental autoimmune encephalomyelitis; Metalloproteinase; Multiple sclerosis; Immunology; Matrix metalloproteinase; Encephalomyelitis; Medicine; Autoimmune disease; Antibody; Pathology; Internal medicine","score_opus":0.054227041330335506,"score_gpt":0.250404241363182,"score_spread":0.1961772000328465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071065554","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9738598,0.017839437,0.0047400882,0.0002415526,0.000055260396,0.00006965338,0.0003569431,0.0001420742,0.0026952347],"genre_scores_gemma":[0.9843137,0.0061199367,0.00452849,0.000164861,0.000086294895,0.00007984711,0.00070829695,0.000022599605,0.0039760494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998803,0.000026136842,0.000009108315,0.000029384675,0.000030652973,0.000024431109],"domain_scores_gemma":[0.9999467,0.0000051235916,0.000017543574,0.000004311827,0.000008834411,0.000017525364],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017389448,0.00039656385,0.00033856492,0.00033011276,0.00019880269,0.00038940576,0.00021899684,0.00041761823,0.0006821612],"category_scores_gemma":[0.00009475565,0.000092043294,0.0001596007,0.00018255955,0.00020174877,0.00036839486,0.00029105606,0.0004635471,0.00025575393],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036282692,0.000043440145,0.00067171175,0.000115179326,0.00001158801,0.00046542202,0.000022636354,0.00007266555,0.99285406,0.00021436054,0.00010491948,0.0050611557],"study_design_scores_gemma":[0.00005605785,0.0006759427,0.042749815,0.000032253913,0.000095439595,0.0029760404,0.000062417465,0.0017618061,0.93590426,0.00022302389,0.015447906,0.000015167849],"about_ca_topic_score_codex":0.00014241134,"about_ca_topic_score_gemma":0.00021888976,"teacher_disagreement_score":0.0006821612,"about_ca_system_score_codex":0.00034671853,"about_ca_system_score_gemma":0.00011256272,"threshold_uncertainty_score":0.002515614},"labels":[],"label_agreement":null},{"id":"W2071760372","doi":"10.1016/s1097-2765(03)00490-8","title":"Regulation of NF-κB Signaling by Pin1-Dependent Prolyl Isomerization and Ubiquitin-Mediated Proteolysis of p65/RelA","year":2003,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":634,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Ubiquitin; PIN1; Ubiquitin ligase; Biology; Proteolysis; NF-κB; Transcription factor; Signal transduction; Cell biology; NFKB1; Cytokine; Proteasome; Protein subunit; Peptidylprolyl isomerase; Biochemistry; Gene; Isomerase; Immunology; Enzyme","score_opus":0.003725735746048316,"score_gpt":0.1919861844017028,"score_spread":0.18826044865565447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2071760372","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9699196,0.013796929,0.009305483,0.0005604859,0.00013567253,0.00006704968,0.00067124225,0.00018741368,0.0053561893],"genre_scores_gemma":[0.99055195,0.0022518896,0.0027390067,0.00013200563,0.00002588574,0.000045566096,0.00058813504,0.000029611341,0.0036359585],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974495,0.000038666487,0.000017125192,0.000057037014,0.000039785384,0.00010238142],"domain_scores_gemma":[0.9998387,0.000014243806,0.00006627824,0.000015337173,0.000017718758,0.00004766568],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029333984,0.0007762445,0.0002809568,0.00042047098,0.00052538776,0.00066531927,0.00035046032,0.00030260274,0.0020872212],"category_scores_gemma":[0.00022709553,0.00035563827,0.0005059593,0.00015761319,0.00039237377,0.00069164793,0.0005211577,0.0008136817,0.0010283539],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000514456,0.00004008842,0.00027969887,0.000086922024,0.000011339391,0.00023897097,0.000026980706,0.00008018828,0.99550796,0.00076098443,0.000100854486,0.0023515727],"study_design_scores_gemma":[0.000045303404,0.00020474201,0.014744919,0.00001644865,0.000017715063,0.0013784362,0.00013151336,0.0011105043,0.9781059,0.0006083631,0.003618831,0.000017341585],"about_ca_topic_score_codex":0.0005205885,"about_ca_topic_score_gemma":0.00070324255,"teacher_disagreement_score":0.0020872212,"about_ca_system_score_codex":0.00073762995,"about_ca_system_score_gemma":0.0002571121,"threshold_uncertainty_score":0.0069825053},"labels":[],"label_agreement":null},{"id":"W2072304559","doi":"10.1038/sj.onc.1210153","title":"Ablation of a peptidyl prolyl isomerase Pin1 from p53-null mice accelerated thymic hyperplasia by increasing the level of the intracellular form of Notch1","year":2006,"lang":"en","type":"article","venue":"Oncogene","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Aging","funders":"","keywords":"PIN1; Biology; Prolyl isomerase; Cancer research; Peptidylprolyl isomerase; Intracellular; Apoptosis; CD8; Cell cycle; Isomerase; Cell biology; Immunology; Antigen; Biochemistry; Enzyme","score_opus":0.02327038068599391,"score_gpt":0.24029229105926644,"score_spread":0.21702191037327254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072304559","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9870948,0.0013543532,0.008142573,0.00026584588,0.00008114092,0.00003395663,0.00074159366,0.0003319944,0.0019536368],"genre_scores_gemma":[0.9905529,0.0007102562,0.002670053,0.00007475772,0.000017700486,0.00003443786,0.00052898645,0.00007705756,0.005333983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975425,0.000018792776,0.000022125529,0.000069380505,0.000072092655,0.00006324508],"domain_scores_gemma":[0.9996958,0.000045846547,0.000098501456,0.0000282751,0.00001966202,0.00011187862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015265708,0.000626367,0.00031870155,0.0006133503,0.00019381709,0.0005360142,0.00034356932,0.00046722937,0.0025016181],"category_scores_gemma":[0.00018818423,0.00035766626,0.00024351201,0.00016630118,0.000511311,0.000448891,0.0003335598,0.001433649,0.00069475424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007494692,0.0000064211436,0.00005428549,0.000011758907,0.0000020681055,0.000052306263,0.0000044493368,0.000024963074,0.99926716,0.000078650795,0.000011134097,0.00041189152],"study_design_scores_gemma":[0.000010140282,0.00006081431,0.00088233355,0.000002467284,0.0000078981175,0.00020661972,0.000010626326,0.00030147083,0.9977843,0.000041964213,0.0006886532,0.000002800688],"about_ca_topic_score_codex":0.00037010422,"about_ca_topic_score_gemma":0.00062124303,"teacher_disagreement_score":0.0025016181,"about_ca_system_score_codex":0.00044741845,"about_ca_system_score_gemma":0.00025340173,"threshold_uncertainty_score":0.008368731},"labels":[],"label_agreement":null},{"id":"W2072929674","doi":"10.1016/j.matbio.2010.10.007","title":"MMPs are less efficient than ADAMTS5 in cleaving aggrecan core protein","year":2010,"lang":"en","type":"article","venue":"Matrix Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":74,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Shriners Hospitals for Children - Canada","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Canadian Institutes of Health Research; National Institutes of Health; Wellcome Trust","keywords":"Aggrecan; Matrix metalloproteinase; Chemistry; Aggrecanase; Core protein; Cell biology; Biochemistry; Medicine; Biology; Osteoarthritis; Pathology; Articular cartilage","score_opus":0.01693210080014667,"score_gpt":0.2845931155551137,"score_spread":0.267661014754967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072929674","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990546,0.004360033,0.003114325,0.0001308667,0.000056484827,0.000025447034,0.0004390095,0.00008463526,0.001243237],"genre_scores_gemma":[0.98969984,0.0010837229,0.003042907,0.00007089907,0.00002141899,0.000019823425,0.0016773969,0.0000432369,0.004340646],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99870586,0.00030127165,0.00021496713,0.00016265785,0.0003865915,0.00022862584],"domain_scores_gemma":[0.9991622,0.0001867852,0.00015399812,0.00014313808,0.00022678435,0.00012712719],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001012577,0.00038362917,0.000639925,0.0007434354,0.0002134589,0.0010765919,0.00034244847,0.0004285002,0.002808223],"category_scores_gemma":[0.0012055947,0.00031057114,0.0006133511,0.0003477618,0.0002891253,0.0005825307,0.00029118956,0.000544247,0.0010664627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047358696,0.00005404121,0.0034927954,0.00013404737,0.000057295903,0.00014948461,0.000046946312,0.00010316361,0.988184,0.00023014142,0.00018413665,0.0068903565],"study_design_scores_gemma":[0.00001772051,0.0003645726,0.014367276,0.000009401102,0.00004364322,0.0014288378,0.000067191155,0.00044986265,0.9795259,0.00008813743,0.003630384,0.0000070773926],"about_ca_topic_score_codex":0.0014550546,"about_ca_topic_score_gemma":0.0009798459,"teacher_disagreement_score":0.002808223,"about_ca_system_score_codex":0.0005175398,"about_ca_system_score_gemma":0.00033803936,"threshold_uncertainty_score":0.009394407},"labels":[],"label_agreement":null},{"id":"W2072979714","doi":"10.1007/s10571-012-9894-3","title":"Nerve Growth Factor-Mediated Regulation of Low Density Lipoprotein Receptor-Related Protein Promoter Activation","year":2012,"lang":"en","type":"article","venue":"Cellular and Molecular Neurobiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; University of Guelph","keywords":"Nerve growth factor; LRP1; Tropomyosin receptor kinase A; Transcription factor; Neurite; Chemistry; Biology; Transfection; Cell biology; Receptor; Molecular biology; Endocrinology; LDL receptor; Biochemistry; Lipoprotein; Gene","score_opus":0.007074796878270084,"score_gpt":0.1994082056061545,"score_spread":0.1923334087278844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2072979714","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9694743,0.0063020247,0.011173781,0.00043125972,0.00018672386,0.000065771914,0.0016238819,0.00023402047,0.010508289],"genre_scores_gemma":[0.9821004,0.0013752653,0.0040683076,0.00014764738,0.00002217419,0.00007282497,0.0020868205,0.000041523,0.010084996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997403,0.000045712895,0.000015823918,0.000065862616,0.00004424498,0.00008809064],"domain_scores_gemma":[0.99981827,0.00006443046,0.000025480009,0.000022767714,0.000029260931,0.00003969726],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027945728,0.00045968476,0.00017577993,0.0004524351,0.0002492722,0.00049414474,0.0002991585,0.00021947888,0.0035697306],"category_scores_gemma":[0.00030399332,0.0002109261,0.0005151311,0.00015524209,0.0003998284,0.00028749584,0.00043638557,0.00062890025,0.0011594573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037077037,0.00004696169,0.0003519402,0.000049767175,0.0000065480976,0.00009306391,0.000038673275,0.00008607972,0.99567837,0.00056013925,0.00013115293,0.0025865426],"study_design_scores_gemma":[0.00004008822,0.00015553099,0.013006247,0.000027707825,0.000013909296,0.0002500377,0.000115549956,0.0016674309,0.9805982,0.0003103418,0.0038030255,0.00001187406],"about_ca_topic_score_codex":0.0029643476,"about_ca_topic_score_gemma":0.004594252,"teacher_disagreement_score":0.0035697306,"about_ca_system_score_codex":0.000955848,"about_ca_system_score_gemma":0.00042985237,"threshold_uncertainty_score":0.01194191},"labels":[],"label_agreement":null},{"id":"W2073441649","doi":"10.1007/s11010-009-0346-4","title":"Potential role of calcineurin in pathogenic conditions","year":2009,"lang":"en","type":"review","venue":"Molecular and Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Calcineurin; Retina; Cell biology; Optic nerve; Cornea; Phosphatase; Signal transduction; Biology; Calmodulin; Ciliary body; Choroid; Sclera; Phosphorylation; Anatomy; Neuroscience; Medicine; Biochemistry; Transplantation; Internal medicine; Genetics","score_opus":0.0066836297710274216,"score_gpt":0.25611923377023615,"score_spread":0.24943560399920872,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073441649","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015846234,0.9975157,0.00034293227,0.00047380128,0.00041177095,0.000003311466,0.00000986249,0.000008756819,0.0010754269],"genre_scores_gemma":[0.0011314338,0.9962004,0.0005736039,0.00041692983,0.0007356249,0.000008231727,0.000027673002,0.0000023322825,0.00090387155],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997991,0.00003068801,0.000032010823,0.00003800984,0.00007965666,0.000020517542],"domain_scores_gemma":[0.9996208,0.00019577837,0.00003796879,0.000017052505,0.00009283146,0.000035528],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009140649,0.0010139216,0.0015577007,0.0020058595,0.00034552126,0.0011242577,0.0013476941,0.0016879708,0.002125221],"category_scores_gemma":[0.0008404949,0.00033076297,0.0004309708,0.0019067816,0.0010643881,0.0015534452,0.0008605337,0.0023924548,0.0016933896],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019580217,0.000098500605,0.00035614098,0.008217376,0.0001120688,0.001381492,0.00006952606,0.00065358245,0.00650603,0.008250533,0.036095906,0.9380629],"study_design_scores_gemma":[0.000047698817,0.00006227414,0.00068305526,0.0012145307,0.00012228715,0.0036955972,0.00005401877,0.00018724901,0.0014251554,0.004600254,0.9878875,0.000020369689],"about_ca_topic_score_codex":0.00085151853,"about_ca_topic_score_gemma":0.0015665479,"teacher_disagreement_score":0.002125221,"about_ca_system_score_codex":0.0007961975,"about_ca_system_score_gemma":0.0011218725,"threshold_uncertainty_score":0.007109642},"labels":[],"label_agreement":null},{"id":"W2073786077","doi":"10.1074/jbc.m707115200","title":"Atrial Natriuretic Peptide Attenuates Elevations in Ca2+ and Protects Hepatocytes by Stimulating Net Plasma Membrane Ca2+ Efflux","year":2007,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Wellcome Trust; McMaster University","keywords":"Efflux; Atrial natriuretic peptide; Internal medicine; Endocrinology; Chemistry; Medicine; Biochemistry","score_opus":0.017034473881030777,"score_gpt":0.26316503768111255,"score_spread":0.24613056380008178,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2073786077","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99478275,0.0025499824,0.0015384324,0.00016498912,0.000052754363,0.000029585544,0.00007060485,0.000059380847,0.0007515866],"genre_scores_gemma":[0.9950617,0.0015482791,0.0018598043,0.00010666078,0.00004924944,0.00004660456,0.000102781196,0.000009534863,0.0012153359],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989295,0.00002081827,0.000012868707,0.000018325527,0.000026287335,0.000028711407],"domain_scores_gemma":[0.9998958,0.000016039805,0.000028021259,0.00001470366,0.000013720855,0.00003173959],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016882492,0.00036287052,0.00049710734,0.000120790086,0.000117079886,0.00019430374,0.00017551833,0.00029119037,0.0007565093],"category_scores_gemma":[0.00013685926,0.00009515006,0.0001746752,0.000076805954,0.0002710618,0.00030207264,0.000187044,0.00067172677,0.00012760432],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006266541,0.000057494588,0.00015247652,0.000051093215,0.0000070014025,0.00008357511,0.000015616426,0.000047032343,0.99603206,0.000038627215,0.00002581083,0.0028625582],"study_design_scores_gemma":[0.0001597268,0.0053049237,0.010701728,0.00000997029,0.000028327808,0.00033947447,0.0000574051,0.0008014043,0.9809461,0.00012351172,0.0015202689,0.0000071299037],"about_ca_topic_score_codex":0.00030801544,"about_ca_topic_score_gemma":0.0005437215,"teacher_disagreement_score":0.0007565093,"about_ca_system_score_codex":0.000112079244,"about_ca_system_score_gemma":0.00024332771,"threshold_uncertainty_score":0.0025307536},"labels":[],"label_agreement":null},{"id":"W2075530203","doi":"10.3389/fphys.2013.00018","title":"Non-catalytic participation of the Pin1 peptidyl-prolyl isomerase domain in target binding","year":2013,"lang":"en","type":"article","venue":"Frontiers in Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Cancer Research Society","keywords":"PIN1; WW domain; Prolyl isomerase; Isomerase; Phosphorylation; Serine; Peptidylprolyl isomerase; Threonine; Biology; Chemistry; Cell biology; Biochemistry; Enzyme; Gene","score_opus":0.006699227771380087,"score_gpt":0.2284541132052335,"score_spread":0.2217548854338534,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075530203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953129,0.0012372098,0.0021849696,0.00007077506,0.00000884422,0.000010369567,0.00019886492,0.000018139011,0.0009578582],"genre_scores_gemma":[0.9973016,0.0003285417,0.0012454948,0.000037983835,0.0000022782065,0.000013756204,0.00043922858,0.0000062596896,0.0006248251],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997093,0.0000374595,0.000021130474,0.000064580796,0.00008651134,0.00008097142],"domain_scores_gemma":[0.9998363,0.000046050765,0.000043779903,0.000018371316,0.000012144575,0.00004332663],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019301302,0.0003352996,0.00028354983,0.00019384443,0.0002590103,0.00045301186,0.00038631633,0.00042375788,0.001746225],"category_scores_gemma":[0.00031160886,0.00018323305,0.0003900628,0.00018871106,0.0002321302,0.00042872064,0.0003157706,0.00052271213,0.00043467298],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001647245,0.00002772781,0.0011821268,0.00007892647,0.000013075412,0.00017114774,0.000017852262,0.00014093998,0.99679875,0.00023307344,0.000027770471,0.0011439562],"study_design_scores_gemma":[0.0000123868695,0.000119767945,0.021830844,0.0000068749628,0.000022027718,0.0010033452,0.00006027953,0.002243025,0.9729585,0.00012842499,0.0016063262,0.000008215135],"about_ca_topic_score_codex":0.0005048886,"about_ca_topic_score_gemma":0.0006854616,"teacher_disagreement_score":0.001746225,"about_ca_system_score_codex":0.00031212057,"about_ca_system_score_gemma":0.00017272549,"threshold_uncertainty_score":0.005841732},"labels":[],"label_agreement":null},{"id":"W2075798277","doi":"10.1152/ajpheart.01041.2010","title":"Role of myosin light chain kinase in cardiotrophin-1-induced cardiac myofibroblast cell migration","year":2011,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Canadian Institutes of Health Research; Health Canada; National Institutes of Health","keywords":"Myofibroblast; Myosin light-chain kinase; Depolarization; Hyperpolarization (physics); Cell biology; Chemistry; Myosin; Internal medicine; Medicine; Biology; Fibrosis","score_opus":0.00782752324452222,"score_gpt":0.20870678478429855,"score_spread":0.20087926153977634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075798277","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98599154,0.010515808,0.0010843128,0.00019072826,0.000072395866,0.00005095595,0.0003622024,0.000042092357,0.0016898529],"genre_scores_gemma":[0.9929128,0.0038076064,0.0010740943,0.00007539761,0.000019561194,0.00007050574,0.00032976104,0.000007816337,0.001702573],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999279,0.000013537583,0.000006008183,0.000015873535,0.00001173649,0.000025100147],"domain_scores_gemma":[0.99994886,0.0000071251634,0.000015009024,0.0000035152466,0.000006075899,0.000019424955],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012229872,0.00035167573,0.00022431026,0.0001422588,0.00015351393,0.00021364378,0.000105006264,0.00029226844,0.00074330467],"category_scores_gemma":[0.00007025226,0.000102440514,0.00021655149,0.00008929585,0.00015094546,0.00014589443,0.000123676,0.00044890612,0.00027583266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020433954,0.000025367863,0.00012926725,0.000055066834,0.0000025043248,0.00003657298,0.0000086467,0.00002120377,0.9987954,0.000049667913,0.00002246761,0.00064949197],"study_design_scores_gemma":[0.00012747568,0.0006312963,0.022288134,0.000038245766,0.000021521844,0.00026985753,0.000045025867,0.0012454183,0.97266555,0.00010665293,0.002551642,0.000009179859],"about_ca_topic_score_codex":0.00031576699,"about_ca_topic_score_gemma":0.0005350319,"teacher_disagreement_score":0.00074330467,"about_ca_system_score_codex":0.00024110333,"about_ca_system_score_gemma":0.0002002203,"threshold_uncertainty_score":0.0024865866},"labels":[],"label_agreement":null},{"id":"W2076127790","doi":"10.1016/j.bbrc.2012.09.092","title":"AT motif binding factor 1 (ATBF1) is highly phosphorylated in embryonic brain and protected from cleavage by calpain-1","year":2012,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Japan Science and Technology Agency; New Energy and Industrial Technology Development Organization; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Calpain; Serine; Phosphorylation; Cell biology; Embryonic stem cell; Alkaline phosphatase; Biology; Biochemistry; Gene; Enzyme","score_opus":0.05205717014682771,"score_gpt":0.340877429206154,"score_spread":0.2888202590593263,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076127790","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9901636,0.0041969083,0.0038136814,0.00023099579,0.00005799416,0.000013032301,0.00065837847,0.00005967302,0.00080570416],"genre_scores_gemma":[0.98804575,0.0015455507,0.0029472045,0.000102735874,0.00003263126,0.000027320477,0.0021130927,0.000043702155,0.005142125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984765,0.000012229089,0.000010965044,0.000043497694,0.000038875904,0.000046835725],"domain_scores_gemma":[0.999684,0.00003431992,0.00015489313,0.00001460775,0.000028518685,0.00008374078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015566662,0.0005104357,0.00030767237,0.00050305476,0.00039220345,0.00039332555,0.00040475148,0.00045102419,0.0021676577],"category_scores_gemma":[0.000259223,0.00027258412,0.00031057882,0.00021865571,0.00028055394,0.00035719157,0.00025655475,0.00071057386,0.0005327782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018212144,0.000009400507,0.00043262297,0.000030780513,0.0000076190013,0.00021503543,0.000014270391,0.000030412042,0.9979395,0.00013050596,0.000073076,0.0009346376],"study_design_scores_gemma":[0.00005708097,0.00026861366,0.050043993,0.000023493349,0.00006314637,0.006066138,0.00012451554,0.0007887145,0.9352825,0.00046098244,0.006796989,0.000023794912],"about_ca_topic_score_codex":0.001192664,"about_ca_topic_score_gemma":0.0017998215,"teacher_disagreement_score":0.0021676577,"about_ca_system_score_codex":0.0004460801,"about_ca_system_score_gemma":0.00026946169,"threshold_uncertainty_score":0.0072515607},"labels":[],"label_agreement":null},{"id":"W2076780854","doi":"10.1016/j.bbrc.2003.08.040","title":"Calreticulin is an upstream regulator of calcineurin","year":2003,"lang":"en","type":"review","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; Canadian Institutes of Health Research","funders":"","keywords":"Calreticulin; Endoplasmic reticulum; Cell biology; Regulator; Biology; Calcineurin; Organelle; Internal medicine; Transplantation; Biochemistry; Medicine","score_opus":0.21665385966673317,"score_gpt":0.467335316395519,"score_spread":0.25068145672878583,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076780854","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013672677,0.99244726,0.0013424236,0.00048333633,0.00049844326,0.000012885674,0.00003512718,0.00004469352,0.0037685968],"genre_scores_gemma":[0.0070785796,0.98650044,0.001190301,0.00040483067,0.00038023994,0.000017207829,0.00012708707,0.0000059367126,0.004295419],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99989045,0.0000073325314,0.00001356525,0.00002963556,0.000045286117,0.000013678346],"domain_scores_gemma":[0.9998529,0.000042593423,0.000027621814,0.0000073069727,0.000050108312,0.000019485651],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003703356,0.0009121773,0.00106333,0.0008311242,0.0002914787,0.00092618796,0.00084569864,0.0008580147,0.0019136646],"category_scores_gemma":[0.00032815724,0.00020847621,0.0001851364,0.001106457,0.00064716506,0.00096655166,0.00052719563,0.0012885524,0.0027740533],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022233042,0.00007826437,0.0003389825,0.004386063,0.00004742196,0.0008184998,0.000050729053,0.0005489653,0.04135033,0.005544401,0.014579283,0.9320346],"study_design_scores_gemma":[0.00003606565,0.00008976462,0.0013301962,0.00049215177,0.00009703231,0.0023732597,0.000066786524,0.00018012252,0.018782044,0.002166419,0.9743654,0.000020824642],"about_ca_topic_score_codex":0.00081411365,"about_ca_topic_score_gemma":0.0011862111,"teacher_disagreement_score":0.0019136646,"about_ca_system_score_codex":0.00075548474,"about_ca_system_score_gemma":0.00073295756,"threshold_uncertainty_score":0.006401837},"labels":[],"label_agreement":null},{"id":"W2076855652","doi":"10.1016/s1053-2498(00)00290-4","title":"ISATX247: a novel calcineurin inhibitor","year":2001,"lang":"en","type":"article","venue":"The Journal of Heart and Lung Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Institute for Nanotechnology; University of Alberta","funders":"","keywords":"Calcineurin; Nephrotoxicity; Pharmacology; In vivo; Medicine; Immunosuppression; Pharmacokinetics; Toxicity; Adverse effect; Bioavailability; Drug; Transplantation; Internal medicine; Biology","score_opus":0.011470910910137343,"score_gpt":0.2606533246248416,"score_spread":0.24918241371470423,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076855652","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89004904,0.067821994,0.009972202,0.002952311,0.0011875017,0.0005528468,0.0024017275,0.0025054778,0.022556916],"genre_scores_gemma":[0.9431501,0.02729268,0.006646605,0.0012061414,0.00035222995,0.00038838782,0.0059129945,0.000105279505,0.014945616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992263,0.000010175338,0.000005970203,0.000014125426,0.000019043202,0.000028055809],"domain_scores_gemma":[0.99995375,0.0000050975086,0.000009544585,0.0000041075573,0.000004817666,0.000022723203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016539676,0.00070255465,0.00068496633,0.0005111419,0.00038060988,0.0005436813,0.0008047896,0.00061846105,0.0018496106],"category_scores_gemma":[0.00012626682,0.00017045911,0.0004102249,0.00038942898,0.00031121162,0.00028757533,0.000242863,0.0013865847,0.0011707603],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003745594,0.0010363639,0.0012253866,0.0006377845,0.00022444823,0.002931578,0.00007746647,0.0021076153,0.84362656,0.0020586443,0.00933203,0.13299659],"study_design_scores_gemma":[0.005899572,0.015521453,0.008914619,0.00009085326,0.0006667661,0.014359946,0.00008900912,0.004490913,0.80692065,0.0010935926,0.14181551,0.00013704022],"about_ca_topic_score_codex":0.00048848253,"about_ca_topic_score_gemma":0.0008926828,"teacher_disagreement_score":0.0018496106,"about_ca_system_score_codex":0.00046715632,"about_ca_system_score_gemma":0.0005637903,"threshold_uncertainty_score":0.006187618},"labels":[],"label_agreement":null},{"id":"W2077145758","doi":"10.1016/j.neuroscience.2008.02.043","title":"Growth cone collapse stimulated by both calpain- and Rho-mediated pathways","year":2008,"lang":"en","type":"article","venue":"Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Calpain; Signal transduction; Growth cone; Cell biology; Motility; Protease; Biology; Biophysics; Intracellular; Rho-associated protein kinase; Neuroscience; Biochemistry; Enzyme","score_opus":0.017652202008295332,"score_gpt":0.22479396387229256,"score_spread":0.20714176186399721,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077145758","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98011214,0.004051724,0.0040463605,0.00044825466,0.000091326336,0.00008468987,0.00033453942,0.00014645733,0.010684531],"genre_scores_gemma":[0.99354917,0.0012411436,0.0013499829,0.0001253856,0.000025665566,0.000055048396,0.0002128226,0.00001896766,0.0034217408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997286,0.000031102445,0.000011940804,0.000027731025,0.000093961746,0.00010665503],"domain_scores_gemma":[0.9998118,0.00003946275,0.00003325386,0.000030157293,0.000036566336,0.000048791702],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022315216,0.00044111564,0.00035188484,0.00045211648,0.00042839604,0.0005002507,0.00028283487,0.00046779314,0.0020234345],"category_scores_gemma":[0.000280787,0.00017190084,0.00054213585,0.00016070525,0.00034587632,0.00039720687,0.00048275723,0.0010932861,0.0003125282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023578589,0.000023576846,0.000092347145,0.000030344288,0.000008800694,0.00014986834,0.000017839338,0.00005891309,0.99794835,0.00040523408,0.00008981631,0.0009391943],"study_design_scores_gemma":[0.000058099562,0.0001562039,0.009835839,0.000017053553,0.000017579192,0.0004135624,0.000068168236,0.0020169835,0.98572415,0.000298203,0.0013817569,0.0000124554135],"about_ca_topic_score_codex":0.0016779939,"about_ca_topic_score_gemma":0.0032329732,"teacher_disagreement_score":0.0020234345,"about_ca_system_score_codex":0.0007742502,"about_ca_system_score_gemma":0.0004364517,"threshold_uncertainty_score":0.006769061},"labels":[],"label_agreement":null},{"id":"W2077235409","doi":"10.1016/j.febslet.2006.04.056","title":"Thermodynamics and stability of the PAAD/DAPIN/PYRIN domain of IFI‐16","year":2006,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Pyrin domain; Domain (mathematical analysis); Chemistry; Stability (learning theory); Protein stability; Computational biology; Thermodynamics; Medicine; Receptor; Biochemistry; Biology; Computer science; Physics; Mathematics; Inflammasome","score_opus":0.005546189999892426,"score_gpt":0.19625033953298562,"score_spread":0.1907041495330932,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077235409","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99908495,0.00024589757,0.0003273025,0.000018722756,0.0000030091987,0.0000018946535,0.00006606621,0.000005915247,0.00024625496],"genre_scores_gemma":[0.99914336,0.00013389983,0.0002390697,0.000005601358,0.0000027898018,0.0000052492837,0.00022342586,0.0000047838594,0.00024191293],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998983,0.0000175896,0.0000048096226,0.00002463026,0.000032545846,0.000022205542],"domain_scores_gemma":[0.99985003,0.000047243255,0.00004183509,0.000010098251,0.00002562445,0.000025136544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016953438,0.00017677378,0.00015249196,0.00017011668,0.00024072595,0.00021699317,0.00021078436,0.00014726934,0.0009884909],"category_scores_gemma":[0.000495028,0.00011887251,0.0001248537,0.00011741249,0.00032957346,0.0002643046,0.00015094936,0.00027996558,0.00022527194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005239797,0.00007519895,0.008986938,0.00008875369,0.000034875775,0.00011956367,0.0001628813,0.005141161,0.978933,0.0011348884,0.00021186066,0.004586989],"study_design_scores_gemma":[0.000047673337,0.00048817822,0.056254037,0.000013297334,0.000026244441,0.0003574205,0.0001663268,0.042488214,0.89666724,0.0014706628,0.0019632294,0.000057468835],"about_ca_topic_score_codex":0.00094884814,"about_ca_topic_score_gemma":0.00060185825,"teacher_disagreement_score":0.0009884909,"about_ca_system_score_codex":0.0004145747,"about_ca_system_score_gemma":0.00014975441,"threshold_uncertainty_score":0.003306806},"labels":[],"label_agreement":null},{"id":"W2077785304","doi":"10.1016/j.jmb.2006.10.078","title":"Functionally Important Residues in the Peptidyl-prolyl Isomerase Pin1 Revealed by Unigenic Evolution","year":2006,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":89,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"PIN1; Isomerase; Peptidylprolyl isomerase; WW domain; Prolyl isomerase; Biology; Mutant; Saccharomyces cerevisiae; Biochemistry; Chemistry; Yeast; Gene","score_opus":0.004446160316695838,"score_gpt":0.24158178987295012,"score_spread":0.23713562955625428,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077785304","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916779,0.0011071065,0.0055445805,0.00008995447,0.000030348705,0.000015144881,0.00013775751,0.000065739325,0.0013314876],"genre_scores_gemma":[0.9953257,0.0004481879,0.0027918348,0.000089442074,0.000015698328,0.0000103896855,0.00038241426,0.00004124595,0.0008950547],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979657,0.000040795887,0.000016172853,0.00005357713,0.000054091615,0.000038759084],"domain_scores_gemma":[0.9996741,0.00007227569,0.00008457196,0.00006296566,0.000036410773,0.000069578615],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045403081,0.00047854715,0.000396835,0.0005937981,0.00036686068,0.00049851544,0.0005273804,0.0005846597,0.000621681],"category_scores_gemma":[0.00041703202,0.00034985525,0.00033485368,0.00049216824,0.00044562054,0.0003971156,0.00077951356,0.0011689266,0.00042972024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030291267,0.000028359143,0.0013364203,0.00003998468,0.000021945138,0.00045940914,0.00006231582,0.00056541717,0.9881414,0.0008305254,0.000039888622,0.008171442],"study_design_scores_gemma":[0.00012557267,0.00060235977,0.09800487,0.00005802372,0.00032402255,0.006849765,0.0003320129,0.010392084,0.86608934,0.0025394952,0.014555508,0.00012701751],"about_ca_topic_score_codex":0.00043433564,"about_ca_topic_score_gemma":0.00052987377,"teacher_disagreement_score":0.000621681,"about_ca_system_score_codex":0.00047030294,"about_ca_system_score_gemma":0.0002584188,"threshold_uncertainty_score":0.0034122467},"labels":[],"label_agreement":null},{"id":"W2078367368","doi":"10.1006/jmbi.2001.4991","title":"The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9 1 1Edited J. Karn","year":2001,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"PIN1; Phosphorylation; Kinase; RNA polymerase II; Molecular biology; Biology; Protein subunit; Transcription (linguistics); Peptidylprolyl isomerase; Protein kinase A; Serine; Biochemistry; Cell biology; Isomerase; Enzyme; Gene expression; Gene; Promoter","score_opus":0.0041121924585240865,"score_gpt":0.2489228580261485,"score_spread":0.2448106655676244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078367368","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9760987,0.008415142,0.0025866183,0.00083188433,0.00038374923,0.0000283449,0.0011314214,0.00019528963,0.010328812],"genre_scores_gemma":[0.97664183,0.0021697166,0.0015604226,0.00020319002,0.000040101022,0.000015973492,0.0021812976,0.000047069207,0.017140456],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987435,0.000009685822,0.0000049018367,0.000031603653,0.00003025534,0.000049133436],"domain_scores_gemma":[0.999948,0.0000057960556,0.000009061226,0.000004479998,0.0000036776114,0.000028994733],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000875555,0.00033080933,0.00019157793,0.00019212562,0.0004645185,0.00055660936,0.00027010372,0.00025259316,0.009939252],"category_scores_gemma":[0.00018328844,0.00021592637,0.0002638509,0.00012418319,0.00017376272,0.00026083394,0.00043133125,0.00048668362,0.003336953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009135263,0.000073650794,0.0009016679,0.00019596262,0.000024716153,0.00034735867,0.000022457769,0.00025181306,0.98831356,0.00065878546,0.0011500637,0.0071464092],"study_design_scores_gemma":[0.00009393478,0.00017255318,0.024694854,0.00003273514,0.000022899347,0.0012850492,0.000089298905,0.003501731,0.95220804,0.00021361328,0.01766613,0.000019038236],"about_ca_topic_score_codex":0.0016155082,"about_ca_topic_score_gemma":0.0031581377,"teacher_disagreement_score":0.009939252,"about_ca_system_score_codex":0.00088727725,"about_ca_system_score_gemma":0.00022021674,"threshold_uncertainty_score":0.033250093},"labels":[],"label_agreement":null},{"id":"W2078669364","doi":"10.1073/pnas.0335507100","title":"The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation","year":2003,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1191,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Ottawa Hospital","funders":"","keywords":"Biology; Proprotein convertase; Cell biology; Molecular biology; Biochemistry","score_opus":0.021335556614124975,"score_gpt":0.2525858779668503,"score_spread":0.2312503213527253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2078669364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97776073,0.011247989,0.005455537,0.0002556216,0.000033285156,0.000060847444,0.00053328375,0.00018333604,0.0044692666],"genre_scores_gemma":[0.9785098,0.004855889,0.0036619755,0.00006660458,0.000018092791,0.000034925488,0.0013164493,0.0000103567045,0.011525906],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999218,0.000006212205,0.000007034344,0.000016847596,0.000028955703,0.000019098658],"domain_scores_gemma":[0.9998913,0.0000063492694,0.00003219552,0.000007711038,0.000023442784,0.00003903095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001010452,0.00038041399,0.00015435793,0.00023917298,0.00020905206,0.00035589637,0.00018098875,0.00021262829,0.0010146459],"category_scores_gemma":[0.00010957857,0.00009383668,0.00017955399,0.00014244788,0.00015455617,0.00016979744,0.0001942137,0.00040964322,0.0005126421],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013985834,0.000021121232,0.0015696094,0.00010610799,0.0000062746362,0.00031289595,0.00002366648,0.00007144458,0.9866774,0.00020006612,0.000109034234,0.010762581],"study_design_scores_gemma":[0.000015516502,0.0002356062,0.03889245,0.00002227691,0.000022574697,0.0033680901,0.0000611931,0.0007744922,0.9455593,0.00019529293,0.010842993,0.000010131872],"about_ca_topic_score_codex":0.000922225,"about_ca_topic_score_gemma":0.0010725535,"teacher_disagreement_score":0.0010146459,"about_ca_system_score_codex":0.00055728486,"about_ca_system_score_gemma":0.00041640358,"threshold_uncertainty_score":0.00404346},"labels":[],"label_agreement":null},{"id":"W2080025627","doi":"10.1021/bi0521801","title":"Structure of Calmodulin Bound to a Calcineurin Peptide:  A New Way of Making an Old Binding Mode<sup>,</sup>","year":2005,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Brookhaven National Laboratory; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Calmodulin; Calcineurin; Peptide; Phosphatase; Myosin light-chain kinase; Binding site; Chemistry; Serine; Biochemistry; Threonine; Protein subunit; Plasma protein binding; Myosin-light-chain phosphatase; Cell biology; Biology; Phosphorylation; Enzyme","score_opus":0.01401189444277023,"score_gpt":0.2842381402259727,"score_spread":0.2702262457832025,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080025627","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93461156,0.015525949,0.024628146,0.0064051114,0.0010635803,0.000056765057,0.00037877454,0.0005158292,0.016814224],"genre_scores_gemma":[0.9708689,0.0049147843,0.016838748,0.0011049283,0.00020415528,0.000027072487,0.0011738748,0.00006564654,0.0048019015],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999651,0.000004470292,0.0000013189482,0.0000072961634,0.000016267659,0.0000056052913],"domain_scores_gemma":[0.9999633,0.0000050476624,0.000008891443,0.0000033826313,0.0000068756376,0.000012394421],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000054007636,0.00021568479,0.00024894375,0.000083818886,0.00043582165,0.00045888446,0.0006519712,0.00036272092,0.0012560119],"category_scores_gemma":[0.00015070055,0.00017552736,0.00011611758,0.0001351298,0.00051694224,0.0005134602,0.00019669229,0.0008647953,0.0003104743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005995032,0.0002016982,0.0023798007,0.0004640999,0.00007254463,0.0025523123,0.00036109667,0.007431337,0.92275876,0.025847265,0.014548519,0.022783011],"study_design_scores_gemma":[0.0005262115,0.0011898335,0.0163643,0.00015429834,0.0001845329,0.005181101,0.00073570036,0.20124413,0.55810094,0.020123057,0.19603504,0.00016081867],"about_ca_topic_score_codex":0.0010268698,"about_ca_topic_score_gemma":0.0010683999,"teacher_disagreement_score":0.0012560119,"about_ca_system_score_codex":0.0004910759,"about_ca_system_score_gemma":0.00021455341,"threshold_uncertainty_score":0.0042018294},"labels":[],"label_agreement":null},{"id":"W2080346460","doi":"10.1046/j.1523-1755.2000.00003.x","title":"Association of cyclophilin A with renal brush border membranes: Redistribution by cyclosporine A","year":2000,"lang":"en","type":"article","venue":"Kidney International","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Cypa; Brush border; Chemistry; Renal cortex; Kidney; Cyclophilin A; Membrane; Internal medicine; Endocrinology; Biochemistry; Pharmacology; Biology; Molecular biology; Medicine","score_opus":0.0027917242145867756,"score_gpt":0.2316742592259644,"score_spread":0.22888253501137762,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080346460","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98563683,0.007451469,0.0030282813,0.0006837689,0.00011937833,0.00001624314,0.0002432753,0.00006430012,0.0027565244],"genre_scores_gemma":[0.9944876,0.0021301804,0.00086334575,0.00009901493,0.00004910915,0.000017353175,0.00025641161,0.000015136719,0.0020819313],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998147,0.000043715667,0.000014072957,0.000032993026,0.00003552696,0.000059042693],"domain_scores_gemma":[0.9998031,0.000040352414,0.000036852245,0.00003602381,0.00002219894,0.000061574516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023959547,0.00024701635,0.00024084141,0.0003697255,0.00060733425,0.0005697846,0.00029794112,0.00037301626,0.0017942897],"category_scores_gemma":[0.00026969635,0.0002738613,0.0004089228,0.0003627289,0.00028556393,0.00039962924,0.0002969783,0.00073675386,0.0004970301],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091021246,0.00004033869,0.00059749774,0.000056566307,0.00004025484,0.00016903676,0.000030647116,0.000072291885,0.9954072,0.00035929665,0.00017514812,0.0021414203],"study_design_scores_gemma":[0.00008218223,0.00015842899,0.03570238,0.000013132677,0.000072834155,0.00080562645,0.00012693382,0.0019676732,0.95668244,0.00018252028,0.0041917497,0.000013996524],"about_ca_topic_score_codex":0.0015657002,"about_ca_topic_score_gemma":0.0021723392,"teacher_disagreement_score":0.0017942897,"about_ca_system_score_codex":0.00078981667,"about_ca_system_score_gemma":0.00034700488,"threshold_uncertainty_score":0.0060024858},"labels":[],"label_agreement":null},{"id":"W2080958543","doi":"10.1007/s11010-009-0206-2","title":"Molecular cloning and biochemical characterization of bovine retina calcineurin","year":2009,"lang":"en","type":"article","venue":"Molecular and Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Calcineurin; Phosphatase; Acid phosphatase; Retina; Complementary DNA; Biochemistry; Cloning (programming); Amino acid; Chemistry; Biology; Enzyme; Molecular biology; Gene; Internal medicine","score_opus":0.003668393941571548,"score_gpt":0.20664734724905368,"score_spread":0.20297895330748214,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2080958543","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9557181,0.011080255,0.02298896,0.0012619057,0.00016756999,0.00018885806,0.0029468364,0.00019526602,0.005452205],"genre_scores_gemma":[0.9311994,0.006221265,0.03257434,0.00031289717,0.00009448717,0.00010911726,0.011515819,0.000114649185,0.017858146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979013,0.000029099596,0.000024675459,0.00005309702,0.00005280046,0.000050251838],"domain_scores_gemma":[0.9994553,0.00014645142,0.00010487193,0.0000913907,0.0001020281,0.00010002446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031284272,0.00040485818,0.0003036217,0.00050967827,0.0005781857,0.0008282066,0.000560501,0.0005455493,0.0010364628],"category_scores_gemma":[0.00061107846,0.00033597337,0.0004484821,0.00040097177,0.00035033002,0.0005564452,0.0002803871,0.0008646634,0.00081951026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000675293,0.000026344016,0.00017820399,0.000034271696,0.000005440222,0.000087365566,0.00003793335,0.00008091592,0.9977349,0.0005123206,0.0000575461,0.0011771165],"study_design_scores_gemma":[0.00003079308,0.00015278149,0.00841524,0.00003074718,0.00003513334,0.00072858715,0.00010479659,0.0013014607,0.97020715,0.00032394778,0.018652653,0.000016700458],"about_ca_topic_score_codex":0.007615784,"about_ca_topic_score_gemma":0.008056773,"teacher_disagreement_score":0.007615784,"about_ca_system_score_codex":0.0016708894,"about_ca_system_score_gemma":0.0008049526,"threshold_uncertainty_score":0.015142918},"labels":[],"label_agreement":null},{"id":"W2081075175","doi":"10.1016/j.ydbio.2005.06.030","title":"Homer modulates NFAT-dependent signaling during muscle differentiation","year":2005,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"NFAT; Myogenesis; Ryanodine receptor; Myocyte; Cell biology; Biology; Calcineurin; Inositol trisphosphate receptor; Signal transduction; Calcium signaling; Calcium; Skeletal muscle; Intracellular; Receptor; Transcription factor; Endocrinology; Inositol; Biochemistry; Internal medicine; Transplantation; Gene","score_opus":0.009259388906644864,"score_gpt":0.22764291085932684,"score_spread":0.21838352195268196,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081075175","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99294335,0.0018617002,0.0021996668,0.00017575354,0.000044983615,0.000010441777,0.00018972144,0.00008446511,0.0024898218],"genre_scores_gemma":[0.99388933,0.0004962574,0.0015771358,0.000090123605,0.000019686917,0.000015346888,0.00023025856,0.000046636877,0.0036352873],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997472,0.000042876596,0.000015576441,0.000046496054,0.000043577274,0.00010418541],"domain_scores_gemma":[0.99981827,0.000032469467,0.000046767796,0.000027967666,0.000017291055,0.000057335215],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020047856,0.0002631874,0.00027022167,0.00025391395,0.00025152398,0.000490918,0.0003521224,0.00033629587,0.0018953407],"category_scores_gemma":[0.00019462041,0.00021440965,0.0002638386,0.00012842032,0.00042284332,0.0003962379,0.00040531676,0.0006771791,0.0005568991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014520656,0.000009622509,0.00014849333,0.000011147636,0.0000019492143,0.000055870485,0.000009843395,0.00001632918,0.99878246,0.00015262602,0.000024477753,0.0006419719],"study_design_scores_gemma":[0.000019347683,0.00009236278,0.010032235,0.0000055393302,0.000009935229,0.00025257308,0.0000616086,0.00047782037,0.98767114,0.000091944436,0.0012812441,0.0000043630685],"about_ca_topic_score_codex":0.0006460733,"about_ca_topic_score_gemma":0.0019138551,"teacher_disagreement_score":0.0018953407,"about_ca_system_score_codex":0.00059906003,"about_ca_system_score_gemma":0.0001593091,"threshold_uncertainty_score":0.0063405633},"labels":[],"label_agreement":null},{"id":"W2081217640","doi":"10.1074/jbc.m513918200","title":"Phosphatidylinositol 3-Kinase-dependent Suppression of the Human Inducible Nitric-oxide Synthase Promoter Is Mediated by FKHRL1","year":2006,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"Canadian Institutes of Health Research; National Institutes of Health","keywords":"Molecular biology; PI3K/AKT/mTOR pathway; Biology; Promoter; Kinase; Transcription factor; Nitric oxide synthase; Transfection; Cancer research; Signal transduction; Chemistry; Cell biology; Gene expression; Biochemistry; Enzyme; Gene","score_opus":0.014431353104718282,"score_gpt":0.25159720396938073,"score_spread":0.23716585086466246,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081217640","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9850057,0.0027314662,0.008090598,0.00027213944,0.000099419376,0.000050588733,0.0010768981,0.00024918676,0.0024239952],"genre_scores_gemma":[0.99324167,0.00061370723,0.0023401836,0.00005521224,0.00000959357,0.00005219221,0.00094247947,0.000017186821,0.0027278974],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998253,0.00002808386,0.000016220385,0.000042886528,0.000037715217,0.000049841943],"domain_scores_gemma":[0.99991345,0.000016079266,0.00003266874,0.000012747495,0.000008119393,0.000016970816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014298788,0.0002892579,0.00024191895,0.00015414834,0.000114129674,0.00021813616,0.00017684106,0.0001794763,0.0012264461],"category_scores_gemma":[0.00010423033,0.00014246622,0.00027522375,0.0001218788,0.00020279079,0.000109672765,0.00019203332,0.00046061116,0.0005549859],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011725213,0.000018616298,0.00007301578,0.000035655576,0.0000029337405,0.00002541214,0.000009686622,0.000051419975,0.99877506,0.000090539346,0.000058980062,0.0007413882],"study_design_scores_gemma":[0.000031032323,0.00016069727,0.003178252,0.000008092123,0.000011963158,0.00016391817,0.000017042785,0.0018594966,0.9909758,0.00004291168,0.0035454459,0.0000054594075],"about_ca_topic_score_codex":0.0008023664,"about_ca_topic_score_gemma":0.0010090902,"teacher_disagreement_score":0.0012264461,"about_ca_system_score_codex":0.00037734842,"about_ca_system_score_gemma":0.00023652698,"threshold_uncertainty_score":0.0041028857},"labels":[],"label_agreement":null},{"id":"W2081528639","doi":"10.1523/jneurosci.3828-08.2008","title":"Genetic Variants of Nogo-66 Receptor with Possible Association to Schizophrenia Block Myelin Inhibition of Axon Growth","year":2008,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":108,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"National Institutes of Health; Dr. Ralph and Marian Falk Medical Research Trust; National Institute of Neurological Disorders and Stroke; National Institute of Mental Health; Yale University","keywords":"Schizophrenia (object-oriented programming); Endophenotype; Genetic association; Neuroscience; Biology; Myelin-associated glycoprotein; Haploinsufficiency; Myelin; Genetics; Gene; Single-nucleotide polymorphism; Psychology; Genotype; Central nervous system; Phenotype; Cognition; Psychiatry","score_opus":0.013070469071390093,"score_gpt":0.22891039004686983,"score_spread":0.21583992097547974,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2081528639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987589,0.00033533014,0.00049550924,0.000036748308,0.0000073362994,0.0000057593547,0.00013000678,0.000014304149,0.00021599825],"genre_scores_gemma":[0.99870646,0.00023641168,0.00060245954,0.000025062533,0.000007302201,0.0000054721113,0.00015764192,0.000012255247,0.00024709685],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997501,0.000059676557,0.00003962091,0.00006413934,0.000056117802,0.00003035093],"domain_scores_gemma":[0.9995877,0.00010793286,0.00018675947,0.00002829454,0.00002013322,0.00006925882],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003130629,0.0008190695,0.00030289573,0.0009157477,0.000319445,0.00019832201,0.00028192735,0.00043182325,0.0018541975],"category_scores_gemma":[0.0006133596,0.00021221938,0.00027551805,0.00039350675,0.0003941217,0.00010173776,0.0002869572,0.00027348846,0.0002066649],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002332629,0.00019978097,0.10144865,0.00012490759,0.00056136714,0.009820117,0.0003022052,0.0008800198,0.8736022,0.0010512478,0.00025142578,0.009425388],"study_design_scores_gemma":[0.0002858341,0.0014315967,0.8419882,0.00007828427,0.0010287522,0.04162994,0.00030854085,0.0042369566,0.103870906,0.0015893165,0.0034666324,0.00008499039],"about_ca_topic_score_codex":0.0018185152,"about_ca_topic_score_gemma":0.003044817,"teacher_disagreement_score":0.0018541975,"about_ca_system_score_codex":0.00021533508,"about_ca_system_score_gemma":0.00020366356,"threshold_uncertainty_score":0.006202936},"labels":[],"label_agreement":null},{"id":"W2082042446","doi":"10.1007/s00441-012-1425-5","title":"Achieving CNS axon regeneration by manipulating convergent neuro-immune signaling","year":2012,"lang":"en","type":"review","venue":"Cell and Tissue Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Canadian Institutes of Health Research; Craig H. Neilsen Foundation","keywords":"Regeneration (biology); Axon; Microglia; Neuroscience; Biology; Immune system; Spinal cord injury; Chemokine; Neuroinflammation; Cell biology; Immunology; Inflammation; Spinal cord","score_opus":0.12434511541798517,"score_gpt":0.3813999270884662,"score_spread":0.25705481167048105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082042446","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0013392755,0.99105513,0.0030186926,0.0004772682,0.00035062173,0.000012596917,0.000046057707,0.000045470137,0.0036547156],"genre_scores_gemma":[0.005354746,0.9894447,0.0024719972,0.00025657043,0.000113063856,0.000020817659,0.000067604225,0.000007658295,0.0022628878],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99986863,0.000013961931,0.0000141513065,0.000028448729,0.000055925426,0.00001881609],"domain_scores_gemma":[0.99989533,0.000044088567,0.000017567048,0.000006031686,0.000025143197,0.000011871291],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056374975,0.0011426504,0.0012033856,0.0011146936,0.00023334112,0.00094196154,0.00090792024,0.00095518347,0.001336401],"category_scores_gemma":[0.00029798856,0.0002846053,0.00032914078,0.0010972463,0.00085754076,0.0009774682,0.00056156656,0.0018049577,0.0012115494],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013661421,0.00012571119,0.00020729197,0.007073417,0.00007530694,0.0003146479,0.000043383352,0.0011826447,0.046163157,0.016226556,0.01152373,0.91692746],"study_design_scores_gemma":[0.000035933754,0.000116588686,0.0008239674,0.00094708183,0.000118563585,0.001176858,0.0000633237,0.00045440183,0.030502073,0.006706993,0.9590134,0.0000408601],"about_ca_topic_score_codex":0.00070932833,"about_ca_topic_score_gemma":0.0014485533,"teacher_disagreement_score":0.001336401,"about_ca_system_score_codex":0.0007482404,"about_ca_system_score_gemma":0.00055447646,"threshold_uncertainty_score":0.0054289103},"labels":[],"label_agreement":null},{"id":"W2082656071","doi":"10.1016/j.ejca.2005.08.011","title":"TFII-I and USF (RBF-2) regulate Ras/MAPK-responsive HIV-1 transcription in T cells","year":2005,"lang":"en","type":"review","venue":"European Journal of Cancer","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research; U.S. Forest Service","keywords":"Enhancer; Transcription factor; Psychological repression; Chromatin; Transcription (linguistics); MAPK/ERK pathway; Cell biology; Biology; Molecular biology; Gene; Genetics; Signal transduction; Gene expression","score_opus":0.0289377814907656,"score_gpt":0.3169885214940776,"score_spread":0.288050740003312,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2082656071","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0008568866,0.99570197,0.0007609393,0.00023869703,0.00033551682,0.000009082371,0.00005471132,0.000037319132,0.002004813],"genre_scores_gemma":[0.004401686,0.9910306,0.001026795,0.00022678163,0.00026724156,0.000019882382,0.00012033029,0.0000053085278,0.002901443],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99992263,0.000008782185,0.00000927842,0.000017318705,0.000028672555,0.000013207784],"domain_scores_gemma":[0.9999088,0.000029701463,0.000018479399,0.0000044542276,0.000025878518,0.000012674981],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032541476,0.000914615,0.000987446,0.00093518436,0.00022331608,0.000714042,0.00078149454,0.00085653993,0.0017961569],"category_scores_gemma":[0.00021212651,0.00027447508,0.00025207183,0.0011757985,0.00039832262,0.0005474701,0.00031782317,0.000980857,0.0022114052],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019559455,0.00003723249,0.00020442143,0.00399502,0.00005181351,0.0002447029,0.000045565022,0.0004619451,0.021759663,0.002528143,0.0163564,0.95411956],"study_design_scores_gemma":[0.000041693846,0.00009290897,0.0010253917,0.00048687018,0.000090026675,0.0009130074,0.00005184446,0.00015721159,0.011518047,0.0010815236,0.9845232,0.000018210525],"about_ca_topic_score_codex":0.0009804332,"about_ca_topic_score_gemma":0.0019499571,"teacher_disagreement_score":0.0017961569,"about_ca_system_score_codex":0.0006250205,"about_ca_system_score_gemma":0.0005722612,"threshold_uncertainty_score":0.0060087442},"labels":[],"label_agreement":null},{"id":"W2083107893","doi":"10.1016/j.cellsig.2012.07.025","title":"Leptin-induced Cardiomyocyte Hypertrophy Reveals both Calcium-dependent and Calcium-independent/RhoA-dependent Calcineurin Activation and NFAT Nuclear Translocation","year":2012,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"RHOA; Calcineurin; NFAT; Leptin; Internal medicine; Endocrinology; Chemistry; Phosphorylation; Biology; Signal transduction; Cell biology; Medicine; Transplantation","score_opus":0.029286810590892685,"score_gpt":0.2504464216621182,"score_spread":0.22115961107122553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083107893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914791,0.0032001866,0.0028102498,0.00022328048,0.00006576328,0.000031182382,0.0005069156,0.000054384753,0.001628895],"genre_scores_gemma":[0.9897832,0.0015674642,0.003515857,0.000108361,0.000030789863,0.000087594126,0.00081060367,0.000040567575,0.00405553],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996069,0.000059381284,0.000039857205,0.00006094294,0.0001228118,0.00011010354],"domain_scores_gemma":[0.9997849,0.000030622556,0.000052469444,0.00003250488,0.000021938324,0.000077601326],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003422685,0.00041756092,0.00041152097,0.00054695795,0.00029809057,0.00039445696,0.00025429358,0.0004327802,0.0020132822],"category_scores_gemma":[0.00019456809,0.00040460163,0.00053296715,0.0003252829,0.00041554627,0.0004617253,0.00036019032,0.00087200606,0.000520887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003234057,0.000014285327,0.00013563677,0.000027854583,0.000007547808,0.000120543315,0.000014351212,0.000011408344,0.9988611,0.00006340469,0.000014999576,0.00040544552],"study_design_scores_gemma":[0.00008868863,0.0002986256,0.019193858,0.000015437457,0.000038711583,0.0010495478,0.00012373726,0.00042710677,0.97734636,0.000096037125,0.0013125761,0.000009279632],"about_ca_topic_score_codex":0.00081567257,"about_ca_topic_score_gemma":0.0019943432,"teacher_disagreement_score":0.0020132822,"about_ca_system_score_codex":0.00040106007,"about_ca_system_score_gemma":0.0002585203,"threshold_uncertainty_score":0.006735146},"labels":[],"label_agreement":null},{"id":"W2083204479","doi":"10.1021/bi0002129","title":"Interaction of Lipid-Bound Myelin Basic Protein with Actin Filaments and Calmodulin","year":2000,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Calmodulin; Actin; Myelin; Chemistry; Actin-binding protein; Myelin basic protein; Cell biology; Actin remodeling; Cytoskeleton; Biochemistry; Biophysics; Biology; Actin cytoskeleton; Neuroscience; Enzyme; Cell","score_opus":0.007561608745680852,"score_gpt":0.23545236111689166,"score_spread":0.22789075237121081,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083204479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9923111,0.0023168284,0.0028407893,0.00009616771,0.000023118053,0.000021871454,0.00008565953,0.000034555,0.0022699498],"genre_scores_gemma":[0.9935091,0.0007265884,0.002705476,0.0000689473,0.000014886021,0.000031145195,0.00027973342,0.000017001666,0.0026470348],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998062,0.00003461464,0.0000076797505,0.000035874,0.00004917171,0.00006643789],"domain_scores_gemma":[0.99988985,0.00002755716,0.000019266383,0.000009392928,0.000020428864,0.000033465418],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011869728,0.00024516066,0.00023253002,0.00015907595,0.0001797431,0.00021173793,0.0003002586,0.0002664563,0.0010285205],"category_scores_gemma":[0.0001936863,0.0001537945,0.00018062102,0.00009671764,0.00017869064,0.00014189532,0.0002614584,0.00046828057,0.00032122637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003301298,0.000010630649,0.000109080014,0.000012924322,0.0000024337962,0.000016103948,0.0000058862297,0.000007840546,0.9994123,0.000038544662,0.00001047757,0.00034087835],"study_design_scores_gemma":[0.000018380568,0.00014217639,0.01098884,0.000007493823,0.00001114707,0.0001473384,0.000021559386,0.0012664655,0.9850583,0.000049439426,0.0022856037,0.0000031012594],"about_ca_topic_score_codex":0.0014699831,"about_ca_topic_score_gemma":0.0013083651,"teacher_disagreement_score":0.0014699831,"about_ca_system_score_codex":0.00040249754,"about_ca_system_score_gemma":0.0001401113,"threshold_uncertainty_score":0.0034406781},"labels":[],"label_agreement":null},{"id":"W2083253537","doi":"10.4236/ojemd.2013.34a2001","title":"Contribution of Estrogen to Sex Dimorphic Expression of Cardiac Natriuretic Peptide and Nitric Oxide Synthase Systems in ANP Gene-Disrupted Mice","year":2013,"lang":"en","type":"article","venue":"Open Journal of Endocrine and Metabolic Diseases","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Heart and Stroke Foundation of Canada","keywords":"Internal medicine; Ovariectomized rat; Endocrinology; Atrial natriuretic peptide; Ventricle; Estrogen; Cyclic guanosine monophosphate; Natriuretic peptide; Hormone; Sexual dimorphism; Biology; Medicine; Nitric oxide; Heart failure","score_opus":0.008608397014072176,"score_gpt":0.2627337238889448,"score_spread":0.2541253268748726,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083253537","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9931306,0.00093401514,0.002685706,0.00017537545,0.000044885383,0.00003999963,0.0017778293,0.000096981836,0.0011145335],"genre_scores_gemma":[0.9836586,0.0014277662,0.0032873636,0.0001906939,0.000028943205,0.00017317696,0.0015595488,0.00014269732,0.009531199],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99965465,0.000044154523,0.000034321725,0.00011290425,0.000098723016,0.00005530486],"domain_scores_gemma":[0.9994623,0.00006198905,0.00022230082,0.000052673175,0.0000353304,0.00016534541],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027527203,0.00053327356,0.00038725583,0.00095520116,0.00020440397,0.00041925267,0.0003649032,0.0004884015,0.002714868],"category_scores_gemma":[0.00022114295,0.00036330786,0.00038501006,0.00021263884,0.00059088046,0.00027088742,0.00033708583,0.00087976136,0.00042429188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004364132,0.00005716691,0.00071575376,0.000032534663,0.000009158681,0.00022186956,0.00002595295,0.000044983633,0.9972656,0.000104748804,0.000034703688,0.0010510875],"study_design_scores_gemma":[0.00019293003,0.0012604675,0.051265523,0.00004742771,0.00011497472,0.0020402938,0.00019858955,0.0008362551,0.93956065,0.00041051742,0.0040456806,0.000026585636],"about_ca_topic_score_codex":0.00033747425,"about_ca_topic_score_gemma":0.0006459133,"teacher_disagreement_score":0.002714868,"about_ca_system_score_codex":0.00031286062,"about_ca_system_score_gemma":0.00029510254,"threshold_uncertainty_score":0.009082139},"labels":[],"label_agreement":null},{"id":"W2083564793","doi":"10.1021/bi010207k","title":"FK506 Blocks Intracellular Ca<sup>2+</sup> Oscillations in Bovine Adrenal Glomerulosa Cells","year":2001,"lang":"en","type":"article","venue":"Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"Protein kinase C; Intracellular; Receptor; Dephosphorylation; Endocrinology; Internal medicine; Phosphorylation; Inositol trisphosphate; Chemistry; Inositol; Cell biology; Biology; Biochemistry; Phosphatase; Medicine","score_opus":0.007695868010913355,"score_gpt":0.22707553816392662,"score_spread":0.21937967015301327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2083564793","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99004525,0.004818507,0.0021026412,0.00028958297,0.000111943875,0.000025872227,0.00059738086,0.0002859473,0.0017229016],"genre_scores_gemma":[0.9955787,0.001158835,0.0010219853,0.00010972178,0.000027749973,0.000025910409,0.0003322541,0.000030369221,0.0017143375],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998068,0.000020024412,0.000031793716,0.00003425017,0.000045201818,0.00006196377],"domain_scores_gemma":[0.99978954,0.00005981401,0.000043826185,0.000039743012,0.000020498377,0.000046592173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012105886,0.00034061115,0.00043529412,0.00021323454,0.0001709497,0.00034231448,0.00032791207,0.00038344055,0.0009923796],"category_scores_gemma":[0.00017438762,0.00012966285,0.00027696052,0.00017897521,0.00028938617,0.00018911003,0.00016648919,0.00061406766,0.00053838984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017678546,0.000016490329,0.00007906516,0.00003401656,0.000004133349,0.000053863638,0.000016752954,0.000036391637,0.9988686,0.00003768365,0.000032377084,0.00064373657],"study_design_scores_gemma":[0.00003397466,0.0003178828,0.008247639,0.000007477691,0.000025953412,0.00018368331,0.00003633427,0.00088796264,0.98769057,0.000040835163,0.0025196425,0.000007970116],"about_ca_topic_score_codex":0.0043099294,"about_ca_topic_score_gemma":0.004510546,"teacher_disagreement_score":0.0043099294,"about_ca_system_score_codex":0.0004964718,"about_ca_system_score_gemma":0.00024270122,"threshold_uncertainty_score":0.008569658},"labels":[],"label_agreement":null},{"id":"W2084546503","doi":"10.1016/j.neuron.2009.08.020","title":"CCM2 Mediates Death Signaling by the TrkA Receptor Tyrosine Kinase","year":2009,"lang":"en","type":"article","venue":"Neuron","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":59,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Tropomyosin receptor kinase A; Receptor tyrosine kinase; Cell biology; Signal transduction; Tyrosine kinase; Receptor; Receptor Protein-Tyrosine Kinases; Neuroscience; Biology; Chemistry; Neurotrophin; Genetics","score_opus":0.012360162051042645,"score_gpt":0.24335037884473243,"score_spread":0.23099021679368978,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084546503","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9658431,0.0060986066,0.0054747723,0.0012253182,0.0002344713,0.000050045946,0.00067592034,0.00027022505,0.020127645],"genre_scores_gemma":[0.99173486,0.0010271689,0.0009491891,0.00009198422,0.000041195402,0.00001971058,0.0004046049,0.00002126175,0.005710074],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999821,0.00002032728,0.000006871343,0.00002372942,0.000053023166,0.000075056996],"domain_scores_gemma":[0.999889,0.000016472075,0.000018690653,0.000012211392,0.000016313805,0.00004719277],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016918073,0.00059593417,0.00028152016,0.00029910603,0.0005635077,0.00079211587,0.00039728318,0.00051531015,0.0027996593],"category_scores_gemma":[0.0002548708,0.000119327,0.00025128573,0.00017953893,0.0003562623,0.0005807301,0.00046710065,0.00077034306,0.0010163771],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048001995,0.000032038522,0.00046440924,0.00007307712,0.0000122019,0.0005295065,0.000024076064,0.00025562407,0.9926328,0.0022438623,0.000676966,0.00257542],"study_design_scores_gemma":[0.00006738346,0.00010452641,0.0055383127,0.000010882203,0.000012821635,0.0010620815,0.000067687964,0.0025242965,0.9827753,0.00076857803,0.0070536393,0.000014641776],"about_ca_topic_score_codex":0.0026673488,"about_ca_topic_score_gemma":0.0031215616,"teacher_disagreement_score":0.0027996593,"about_ca_system_score_codex":0.0017652981,"about_ca_system_score_gemma":0.000657118,"threshold_uncertainty_score":0.012808204},"labels":[],"label_agreement":null},{"id":"W2084865513","doi":"10.1074/jbc.m611522200","title":"Cyclosporin A and FK506 Inhibit IL-12p40 Production through the Calmodulin/Calmodulin-dependent Protein Kinase-activated Phosphoinositide 3-Kinase in Lipopolysaccharide-stimulated Human Monocytic Cells","year":2007,"lang":"en","type":"retraction","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":true,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health Research Institute; Vancouver Coastal Health; University of British Columbia; Ottawa Hospital; Children's Hospital of Eastern Ontario; University of Ottawa","funders":"","keywords":"Phosphoinositide 3-kinase; Cell biology; Calcineurin; Calmodulin; CAMK; PI3K/AKT/mTOR pathway; Kinase; Protein kinase A; Biology; Signal transduction; Chemistry; Biochemistry; Internal medicine; Enzyme; Medicine","score_opus":0.02791962191577392,"score_gpt":0.2829443093566646,"score_spread":0.2550246874408907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2084865513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888206,0.0054820143,0.002066187,0.0003368037,0.00013283211,0.00007964528,0.0005520576,0.00015556432,0.0023742206],"genre_scores_gemma":[0.9939144,0.0022149843,0.001243069,0.00009075915,0.000041494906,0.00008852187,0.00046408296,0.000009986263,0.0019327443],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999889,0.000018100493,0.000015637745,0.000014822331,0.00002309822,0.000039357325],"domain_scores_gemma":[0.9999256,0.000012141027,0.000015891783,0.000009980728,0.0000075048492,0.000028867473],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000098564204,0.00031135706,0.00027893262,0.0002063113,0.0001799132,0.00023472658,0.00013908473,0.00021385432,0.0010270625],"category_scores_gemma":[0.000096703065,0.00011358162,0.0002670845,0.00019158908,0.0001623861,0.0001093066,0.00012558431,0.0006126743,0.00040483582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044298088,0.00009856893,0.00016656374,0.00006835188,0.00000752997,0.000068696274,0.000017401802,0.00008015386,0.99673426,0.000065411565,0.00013788014,0.0021122615],"study_design_scores_gemma":[0.0003051468,0.0014747438,0.0117467325,0.000013242122,0.000049385388,0.00032899267,0.00003630084,0.0015725627,0.97884136,0.00007006853,0.0055521433,0.000009397327],"about_ca_topic_score_codex":0.0012912959,"about_ca_topic_score_gemma":0.0018069356,"teacher_disagreement_score":0.0012912959,"about_ca_system_score_codex":0.00021622838,"about_ca_system_score_gemma":0.00037360805,"threshold_uncertainty_score":0.0034359097},"labels":[],"label_agreement":null},{"id":"W2085321698","doi":"10.1016/j.biochi.2004.10.009","title":"Non-catalytic domains of subunit A negatively regulate the activity of calcineurin","year":2004,"lang":"en","type":"article","venue":"Biochimie","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"National Natural Science Foundation of China","keywords":"Calcineurin; Protein subunit; Chemistry; Phosphatase; Catalysis; Enzyme activator; Enzyme; Enzyme kinetics; Calmodulin; Stereochemistry; Biochemistry; Biophysics; Active site; Biology","score_opus":0.013460136253336925,"score_gpt":0.2515034070285412,"score_spread":0.23804327077520426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085321698","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99351233,0.0020158244,0.0020136617,0.00019307126,0.000095965195,0.0000069853495,0.00009885398,0.00004913066,0.002014217],"genre_scores_gemma":[0.9977272,0.00033964167,0.0005076876,0.00007665262,0.00002028483,0.0000053793647,0.00015404026,0.000023687564,0.0011453761],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998074,0.00003958991,0.000018698203,0.000036856345,0.000053442174,0.00004408183],"domain_scores_gemma":[0.99950826,0.00014680627,0.00008703542,0.000079542406,0.00006538146,0.000113030444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020418658,0.00033783348,0.00018235878,0.00018879853,0.0003694737,0.0006489315,0.00036143945,0.0003182971,0.0015503753],"category_scores_gemma":[0.0005353599,0.00016792744,0.00020886218,0.00012725072,0.00041397146,0.00033015996,0.0002922843,0.0006183146,0.0006929111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016114941,0.00002440042,0.0005624876,0.000014320717,0.0000038594517,0.00011044173,0.000016911641,0.000056850586,0.9972492,0.0005429431,0.00010677218,0.0011506448],"study_design_scores_gemma":[0.000049829447,0.000121701036,0.020270253,0.000012560108,0.000020262241,0.0019791366,0.000091965405,0.0025304046,0.96912956,0.0009903123,0.0047925925,0.000011546321],"about_ca_topic_score_codex":0.0005225692,"about_ca_topic_score_gemma":0.00063462456,"teacher_disagreement_score":0.0015503753,"about_ca_system_score_codex":0.0005129268,"about_ca_system_score_gemma":0.00027197096,"threshold_uncertainty_score":0.005186498},"labels":[],"label_agreement":null},{"id":"W2085364628","doi":"10.1073/pnas.1019711108","title":"Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex","year":2011,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":290,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; American Cancer Society; Canadian Institutes of Health Research; Leukemia and Lymphoma Society; National Cancer Institute; National Institutes of Health","keywords":"NFAT; Cell biology; Biology; Scaffold protein; Transcription factor; Molecular biology; Signal transduction; Biochemistry; Gene","score_opus":0.05750135098058848,"score_gpt":0.27082127792798677,"score_spread":0.2133199269473983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2085364628","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97377634,0.0075435373,0.013379741,0.00015981786,0.00011160417,0.000036761543,0.00044577642,0.00047933336,0.004067051],"genre_scores_gemma":[0.99108475,0.0012976555,0.003399039,0.00006206131,0.00003231314,0.000038271162,0.00077035837,0.000038951293,0.0032765265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998319,0.000015954904,0.000012578398,0.00007360677,0.00003655693,0.000029285675],"domain_scores_gemma":[0.9998838,0.000011835884,0.000046948862,0.00000987437,0.000015635365,0.000031969084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109442204,0.0004190157,0.00015496877,0.00016387264,0.0002802564,0.00033334646,0.00013022899,0.00018391972,0.0011977712],"category_scores_gemma":[0.00014554524,0.0000961037,0.00028236635,0.00010000897,0.00022314557,0.00019624719,0.00026645273,0.00028548937,0.00042243698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000061733066,0.000008148216,0.00041616187,0.000026250693,0.0000049771156,0.000053503423,0.000019238854,0.00003278171,0.99754167,0.00015895716,0.00007702333,0.0015995984],"study_design_scores_gemma":[0.00002226217,0.0002138303,0.017890485,0.000013724641,0.000020063573,0.00044711074,0.00004882011,0.0012709746,0.96961415,0.00021833403,0.010232837,0.000007294609],"about_ca_topic_score_codex":0.000623555,"about_ca_topic_score_gemma":0.001060747,"teacher_disagreement_score":0.0011977712,"about_ca_system_score_codex":0.00048793847,"about_ca_system_score_gemma":0.00020560631,"threshold_uncertainty_score":0.004006982},"labels":[],"label_agreement":null},{"id":"W2089442495","doi":"10.1006/bbrc.2001.4394","title":"Mutations of the C-Terminal End of Cathepsin K Affect Proenzyme Secretion and Intracellular Maturation","year":2001,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"","keywords":"Secretion; Brefeldin A; Intracellular; Cathepsin D; Tunicamycin; Cathepsin E; Cathepsin O; Cathepsin C; Cathepsin; Cathepsin L; Cathepsin L1; Cathepsin B; Biology; Cathepsin H; Cathepsin A; Secretory pathway; Cathepsin S; Lysosome; Biochemistry; Cell biology; Golgi apparatus; Endoplasmic reticulum; Enzyme; Unfolded protein response","score_opus":0.045527000407276294,"score_gpt":0.34664557288072273,"score_spread":0.3011185724734464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089442495","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99376714,0.00051007257,0.003413137,0.00017850638,0.00012840104,0.00004428771,0.0005117674,0.0001156171,0.0013311044],"genre_scores_gemma":[0.99684143,0.0002426404,0.001310435,0.00006909468,0.00002451869,0.00001903708,0.00027311977,0.00006194276,0.0011577657],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994611,0.00011921097,0.00016093535,0.00007068912,0.000103319726,0.00008468283],"domain_scores_gemma":[0.99868315,0.00039996053,0.00041377443,0.00016403182,0.0000777173,0.00026131893],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029377532,0.0010060291,0.0005379925,0.0005635375,0.0004251267,0.0006939327,0.00057813444,0.0015450704,0.0020499728],"category_scores_gemma":[0.0009558912,0.00047998372,0.0009793073,0.00036662733,0.0012006412,0.0004972592,0.00067601004,0.0012117698,0.0012957081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008332824,0.000079856385,0.00057946576,0.000056441026,0.000052209572,0.0016358456,0.000053568372,0.0005993837,0.9940356,0.0004866892,0.000113152535,0.001474441],"study_design_scores_gemma":[0.0001595529,0.000303472,0.0041805436,0.000017360406,0.00009922684,0.0046486687,0.000068975576,0.0028966658,0.9848106,0.00025289477,0.0025205603,0.000041588253],"about_ca_topic_score_codex":0.0011610365,"about_ca_topic_score_gemma":0.00089815666,"teacher_disagreement_score":0.0020499728,"about_ca_system_score_codex":0.0008171456,"about_ca_system_score_gemma":0.0004367012,"threshold_uncertainty_score":0.006857872},"labels":[],"label_agreement":null},{"id":"W2089738694","doi":"10.1139/y06-072","title":"Normalization of the calcineurin pathway underlies the regression of hypertensive hypertrophy induced by Na<sup>+</sup>/H<sup>+</sup>exchanger-1 (NHE-1) inhibitionThis paper is one of a selection of papers published in this Special Issue, entitled The Cellular and Molecular Basis of Cardiovascular Dysfunction, Dhalla 70th Birthday Tribute.","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Calcineurin; NFAT; Internal medicine; Endocrinology; Muscle hypertrophy; Left ventricular hypertrophy; Sodium–hydrogen antiporter; Brain natriuretic peptide; Medicine; Myocyte; Blood pressure; Chemistry; Heart failure; Sodium","score_opus":0.008684616841299684,"score_gpt":0.21008824600859222,"score_spread":0.20140362916729254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089738694","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98982936,0.0051978366,0.0022766036,0.000301991,0.00014969954,0.00003404966,0.00024104527,0.0002261933,0.0017431804],"genre_scores_gemma":[0.9906013,0.002944818,0.0010082208,0.00010889175,0.00008259419,0.000047325753,0.0003473567,0.00003195759,0.004827609],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998666,0.000013188969,0.00001046136,0.00002407055,0.000036762372,0.000048911454],"domain_scores_gemma":[0.999856,0.000007417012,0.000047275716,0.000011434714,0.00001421558,0.0000635775],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016983613,0.00042240054,0.0005056797,0.00025438282,0.00018990455,0.00035917087,0.00025810802,0.00026142623,0.0027701766],"category_scores_gemma":[0.00010352466,0.00019330512,0.00029844034,0.00011249469,0.00031514923,0.00029275255,0.00023994959,0.0013778015,0.0004473775],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046653103,0.0001045248,0.00039975034,0.000039147413,0.000011732358,0.00007830763,0.0000132283085,0.000008449581,0.9960568,0.000062462124,0.000087883585,0.002671196],"study_design_scores_gemma":[0.00010681481,0.0017318446,0.06420459,0.000018733885,0.00010310901,0.00089351274,0.000121657096,0.0007926271,0.92846954,0.00016333014,0.0033816465,0.000012488315],"about_ca_topic_score_codex":0.00042632836,"about_ca_topic_score_gemma":0.001048744,"teacher_disagreement_score":0.0027701766,"about_ca_system_score_codex":0.00019866398,"about_ca_system_score_gemma":0.00028977988,"threshold_uncertainty_score":0.009267211},"labels":[],"label_agreement":null},{"id":"W2089822721","doi":"10.1016/j.jmgm.2015.04.009","title":"Molecular docking study of macrocycles as Fk506-binding protein inhibitors","year":2015,"lang":"en","type":"article","venue":"Journal of Molecular Graphics and Modelling","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Atlantic Canada Opportunities Agency","keywords":"Docking (animal); Plasmodium falciparum; Active site; Computational biology; Binding site; Stereochemistry; Chemistry; Enzyme; Biochemistry; Biology; Malaria; Medicine","score_opus":0.025884083499622155,"score_gpt":0.2672076725331679,"score_spread":0.24132358903354575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2089822721","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9895822,0.00139765,0.0038208005,0.00019940124,0.00004372572,0.000032551823,0.00014037538,0.00011126912,0.0046719764],"genre_scores_gemma":[0.9965946,0.0005323913,0.0016331885,0.000020255735,0.0000024326164,0.00001747731,0.00009291159,0.000021107913,0.001085662],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99988794,0.000029814133,0.000004132953,0.000015579271,0.000027860042,0.000034621364],"domain_scores_gemma":[0.999923,0.000032208147,0.000008113433,0.0000054443435,0.0000142883255,0.000016955755],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013078052,0.0004628515,0.0007675612,0.00031733027,0.0004851089,0.0004606186,0.00061507546,0.00034546736,0.0037845513],"category_scores_gemma":[0.00029795733,0.00023281442,0.00033081693,0.00039352474,0.00019036194,0.00028631993,0.00028181795,0.00050139596,0.00027962492],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038970015,0.0008717076,0.0041765682,0.00061148586,0.0003639756,0.001218549,0.00031012855,0.6741563,0.26201192,0.016227657,0.004206552,0.031948112],"study_design_scores_gemma":[0.00021255326,0.0008959731,0.001841143,0.000026850665,0.000095363794,0.00009218256,0.00018760067,0.9285651,0.06445923,0.0011214167,0.002441555,0.00006104772],"about_ca_topic_score_codex":0.0067416267,"about_ca_topic_score_gemma":0.0055094464,"teacher_disagreement_score":0.0067416267,"about_ca_system_score_codex":0.0005365492,"about_ca_system_score_gemma":0.00039697668,"threshold_uncertainty_score":0.013404727},"labels":[],"label_agreement":null},{"id":"W2091328252","doi":"10.1016/s0171-2985(01)80015-2","title":"Engagement of CD147 Molecule-Induced Cell Aggregation through the Activation of Protein Kinases and Reorganization of the Cytoskeleton","year":2001,"lang":"en","type":"article","venue":"Immunobiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Associated Medical Services","funders":"Thailand Research Fund; National Science and Technology Development Agency","keywords":"Cell biology; Cytoskeleton; Protein kinase C; Tyrosine kinase; Cytochalasin D; Signal transduction; Chemistry; Intracellular; Cell; Biology; Biochemistry","score_opus":0.01383819738086868,"score_gpt":0.24391785653215647,"score_spread":0.2300796591512878,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091328252","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99447733,0.0014313473,0.0014449873,0.00022928721,0.00004471026,0.000023470811,0.00012610777,0.000032603715,0.002190186],"genre_scores_gemma":[0.99706584,0.00047879395,0.0007473786,0.00006980436,0.000016965956,0.000028044251,0.00021350094,0.000005311973,0.0013744169],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987876,0.000018878509,0.0000069763737,0.000013608187,0.000021519301,0.000060093753],"domain_scores_gemma":[0.9999453,0.000013872691,0.000011388882,0.000008632895,0.0000059992867,0.000014790207],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009472791,0.00021834073,0.0001766444,0.00015526148,0.00019693436,0.00030519612,0.000093331844,0.00032583973,0.0011572107],"category_scores_gemma":[0.00012563104,0.00012623252,0.00021135792,0.00013385965,0.00013580732,0.00017986381,0.00016389733,0.0005623517,0.00027534997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032356178,0.000052851,0.00021436809,0.000028806422,0.0000066910634,0.00018068551,0.000013427054,0.000055338056,0.9971621,0.0003092779,0.00014156668,0.0015114214],"study_design_scores_gemma":[0.000043786935,0.00016001603,0.006661739,0.0000042369247,0.000009455719,0.00033636516,0.000018445779,0.0011231633,0.9896143,0.000099116405,0.0019259154,0.00000349898],"about_ca_topic_score_codex":0.00033413296,"about_ca_topic_score_gemma":0.0007064305,"teacher_disagreement_score":0.0011572107,"about_ca_system_score_codex":0.0005034978,"about_ca_system_score_gemma":0.00016708381,"threshold_uncertainty_score":0.0038713217},"labels":[],"label_agreement":null},{"id":"W2091412980","doi":"10.1074/jbc.m802869200","title":"Resveratrol Inhibits Cardiac Hypertrophy via AMP-activated Protein Kinase and Akt","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":245,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; European Commission; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Agence Nationale de la Recherche; Heart and Stroke Foundation of Canada","keywords":"Resveratrol; Protein kinase B; AMPK; Protein kinase A; AMP-activated protein kinase; Cell biology; Kinase; PI3K/AKT/mTOR pathway; Chemistry; Myocyte; Phosphorylation; Biology; Signal transduction; Biochemistry","score_opus":0.0216098940061603,"score_gpt":0.23241676003371806,"score_spread":0.21080686602755777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2091412980","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98125744,0.007728988,0.0027155972,0.00043757452,0.000104738974,0.000043098986,0.0002489144,0.00016363687,0.0073001077],"genre_scores_gemma":[0.9889971,0.0046909302,0.0016243518,0.00015133723,0.00004799162,0.000034213193,0.0004243285,0.000013209898,0.0040165824],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999093,0.000027229653,0.000008236687,0.000010461886,0.000022669985,0.000022095346],"domain_scores_gemma":[0.9999609,0.000006724898,0.000013063001,0.000003951404,0.0000052918804,0.00001007507],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011350453,0.0003682923,0.00018880863,0.00026019712,0.00014258486,0.00018154216,0.00015522078,0.00025518567,0.0010309858],"category_scores_gemma":[0.000083429346,0.0001510912,0.0002875271,0.00007798116,0.00018723654,0.00015459227,0.00014016528,0.00040022994,0.0003232161],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058741734,0.00012783594,0.00027604905,0.00011853941,0.000029098157,0.000047103764,0.0000143138,0.00013051787,0.9930056,0.00026391775,0.0001288864,0.0052706944],"study_design_scores_gemma":[0.00030686462,0.0027647964,0.025486268,0.00003513524,0.00016781408,0.0003901865,0.000046950416,0.0015482429,0.95973533,0.00043995644,0.009060492,0.000017910874],"about_ca_topic_score_codex":0.00038414705,"about_ca_topic_score_gemma":0.0015345146,"teacher_disagreement_score":0.0010309858,"about_ca_system_score_codex":0.0001823767,"about_ca_system_score_gemma":0.00021985442,"threshold_uncertainty_score":0.0034489632},"labels":[],"label_agreement":null},{"id":"W2092576581","doi":"10.1038/srep02985","title":"Functional role of the flexible N-terminal extension of FKBP38 in catalysis","year":2013,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Biomedical Research Council; National Medical Research Council; Singapore Millennium Foundation","keywords":"Calmodulin; Isomerase; Cell biology; Biochemistry; Chemistry; Enzyme activator; Enzyme; Biology","score_opus":0.00993515230130096,"score_gpt":0.22349399369519946,"score_spread":0.2135588413938985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2092576581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952962,0.0015504912,0.0017866872,0.000079232734,0.000016829803,0.000009517366,0.000039943134,0.000021389586,0.0011997761],"genre_scores_gemma":[0.9981421,0.00018003311,0.00089262525,0.000020523274,0.0000060038396,0.0000053540093,0.00007498987,0.000004480539,0.00067397556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999267,0.000012310025,0.0000051546544,0.000017193017,0.000017149783,0.000021574355],"domain_scores_gemma":[0.99987614,0.000027319504,0.000028581433,0.000014057417,0.000009090314,0.0000447665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001727548,0.0002692465,0.00018564037,0.000049970346,0.00019561687,0.000227263,0.00022457947,0.00030269826,0.0015663755],"category_scores_gemma":[0.00020498365,0.00009013038,0.00020398929,0.000047835907,0.0002718455,0.00026965237,0.00019089798,0.00036479553,0.0005784302],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018418666,0.000020059688,0.00025365307,0.00002445275,0.0000033134475,0.00013709263,0.000013216781,0.00010004242,0.9978479,0.00016282419,0.00002042157,0.0012329133],"study_design_scores_gemma":[0.000052668438,0.00021636586,0.014529539,0.000014521594,0.000011493882,0.0010887131,0.00003433659,0.002044115,0.9789686,0.00028791736,0.0027360157,0.000015722924],"about_ca_topic_score_codex":0.00041858057,"about_ca_topic_score_gemma":0.0004911164,"teacher_disagreement_score":0.0015663755,"about_ca_system_score_codex":0.00031629787,"about_ca_system_score_gemma":0.00015270092,"threshold_uncertainty_score":0.0052400827},"labels":[],"label_agreement":null},{"id":"W2093520530","doi":"10.1007/s000110050747","title":"Calcium-dependent interleukin-8 gene expression in T84 human colonic epithelial cells","year":2001,"lang":"en","type":"article","venue":"Inflammation Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Gene expression; Calcium; Gene; Allergy; Rheumatology; Calcium-binding protein; Interleukin 22; Internal medicine; Interleukin; Molecular biology; Immunology; Chemistry; Medicine; Biology; Biochemistry; Cytokine","score_opus":0.0605404192187277,"score_gpt":0.3750028374196143,"score_spread":0.3144624182008866,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093520530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9926196,0.0016431186,0.0016559742,0.00028049498,0.00006668772,0.000055563138,0.0015227814,0.000049787766,0.0021059264],"genre_scores_gemma":[0.9866072,0.0014838995,0.002825706,0.00011581782,0.000046592726,0.00014291175,0.0037657688,0.000023986717,0.004988039],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99963045,0.000068984125,0.00004174517,0.00006371184,0.00007972955,0.000115449235],"domain_scores_gemma":[0.9997558,0.000087965236,0.000026574793,0.00005238702,0.00004819817,0.000029100122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022285046,0.0002408125,0.00039161617,0.0003966977,0.00033272416,0.00048010383,0.00016489084,0.000322152,0.0022930205],"category_scores_gemma":[0.00027037962,0.000202157,0.00041083051,0.000591745,0.00033223414,0.00038396945,0.00020692301,0.00084462797,0.00077806856],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00056850235,0.000035511388,0.00018823596,0.000051908308,0.0000042080565,0.0000717423,0.00006222121,0.000032364926,0.998262,0.00007858735,0.00004635721,0.00059851946],"study_design_scores_gemma":[0.00012454977,0.0006400805,0.014616649,0.000013578431,0.000023685585,0.00032335066,0.0002495776,0.0010765246,0.9796053,0.000103020306,0.0032129344,0.000010783988],"about_ca_topic_score_codex":0.0014674355,"about_ca_topic_score_gemma":0.0015232792,"teacher_disagreement_score":0.0022930205,"about_ca_system_score_codex":0.00037220918,"about_ca_system_score_gemma":0.00035679454,"threshold_uncertainty_score":0.007670939},"labels":[],"label_agreement":null},{"id":"W2094133290","doi":"10.1016/j.cardiores.2004.11.026","title":"Emerging evidence for the role of cardiotrophin-1 in cardiac repair in the infarcted heart","year":2005,"lang":"en","type":"review","venue":"Cardiovascular Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; St. Boniface Hospital","funders":"Canadian Institutes of Health Research; Manitoba Health Research Council; Heart and Stroke Foundation of Canada","keywords":"Cardiology; Medicine; Heart failure; Myofibroblast; Internal medicine; Cardiac fibrosis; Myocardial infarction; Cardiac myocyte; valvular heart disease; Heart disease; Fibrosis","score_opus":0.15838984543199952,"score_gpt":0.4450117286355662,"score_spread":0.2866218832035667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094133290","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.038580228,0.95040596,0.0017646654,0.0033172658,0.00052198494,0.00001889883,0.00015260658,0.00002759715,0.0052107703],"genre_scores_gemma":[0.098190784,0.8950878,0.0019805704,0.0015902315,0.0013120099,0.00002918388,0.00021724188,0.00000525681,0.001586813],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999219,0.000014044726,0.000010164127,0.00001739812,0.000022783324,0.000013786955],"domain_scores_gemma":[0.999574,0.00018574392,0.000090451525,0.00001688342,0.000061468774,0.00007144858],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049086206,0.00026195918,0.00032748436,0.0004749251,0.00012242323,0.00057916826,0.00027857782,0.00052749144,0.0020423993],"category_scores_gemma":[0.00032064167,0.00008682906,0.00020884027,0.00034764464,0.0005590117,0.00054100924,0.00033498427,0.0011541393,0.0004316788],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002104608,0.00057162653,0.016357865,0.01818228,0.00031882845,0.0040176017,0.0006454257,0.00044153852,0.3637213,0.014023159,0.009396502,0.5702192],"study_design_scores_gemma":[0.0002881579,0.0061525856,0.24854562,0.0065945312,0.0010472465,0.012729374,0.002219261,0.00095326145,0.09303479,0.020190304,0.60813415,0.00011072467],"about_ca_topic_score_codex":0.00012353703,"about_ca_topic_score_gemma":0.00029833338,"teacher_disagreement_score":0.0020423993,"about_ca_system_score_codex":0.00016122527,"about_ca_system_score_gemma":0.00025814568,"threshold_uncertainty_score":0.00683254},"labels":[],"label_agreement":null},{"id":"W2094214128","doi":"10.1074/jbc.m100208200","title":"Cooperative Activation by GATA-4 and YY1 of the Cardiac B-type Natriuretic Peptide Promoter","year":2001,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"U.S. Public Health Service","keywords":"Natriuretic peptide; YY1; NPR1; NPR2; Peptide; Internal medicine; Chemistry; Promoter; Endocrinology; Medicine; Gene; Biochemistry; Heart failure; Gene expression","score_opus":0.014794971693150789,"score_gpt":0.24750121651975204,"score_spread":0.23270624482660127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094214128","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9866152,0.0037032112,0.006785638,0.00015412978,0.000052513686,0.000020704769,0.00013095903,0.00008517832,0.002452504],"genre_scores_gemma":[0.9934129,0.00079226017,0.0029324407,0.00005419439,0.000018721204,0.000030505136,0.00030847054,0.00001754707,0.0024330586],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996214,0.000084365885,0.000015242351,0.00007283969,0.000098875666,0.000107227745],"domain_scores_gemma":[0.9998223,0.000038654176,0.000037177615,0.000016911788,0.000022028415,0.00006296653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029840137,0.0003609462,0.00027733415,0.00025885054,0.00021849797,0.00036748513,0.00029024246,0.00022225609,0.0013144334],"category_scores_gemma":[0.00030444836,0.00034361237,0.00032659734,0.00011020469,0.00032131706,0.0002802759,0.0010426412,0.00041064393,0.0007195666],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011425816,0.00001353904,0.00060794456,0.000031726013,0.0000059309227,0.00008206452,0.000035656907,0.000098093224,0.99724495,0.00028073092,0.000065584354,0.0014194234],"study_design_scores_gemma":[0.00007871139,0.00022421379,0.022131618,0.000019568652,0.000033864784,0.0006839311,0.00014072456,0.0062128976,0.9620004,0.00068168464,0.0077759866,0.000016480328],"about_ca_topic_score_codex":0.0005027434,"about_ca_topic_score_gemma":0.00076385005,"teacher_disagreement_score":0.0013144334,"about_ca_system_score_codex":0.00038875113,"about_ca_system_score_gemma":0.00027172267,"threshold_uncertainty_score":0.0043972135},"labels":[],"label_agreement":null},{"id":"W2094274661","doi":"10.1016/j.micinf.2011.07.009","title":"Porphyromonas gingivalis-mediated shedding of extracellular matrix metalloproteinase inducer (EMMPRIN) by oral epithelial cells: a potential role in inflammatory periodontal disease","year":2011,"lang":"en","type":"article","venue":"Microbes and Infection","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Canadian Institutes of Health Research","keywords":"Porphyromonas gingivalis; Secretion; Periodontitis; Metalloproteinase; Matrix metalloproteinase; Extracellular matrix; Cytokine; Basigin; Chronic periodontitis; Chemistry; Immunology; Biology; Cell biology; Medicine; Internal medicine; Biochemistry","score_opus":0.006476113103198154,"score_gpt":0.20451524669253734,"score_spread":0.1980391335893392,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2094274661","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9918172,0.003762666,0.0022128941,0.00036695812,0.000044176493,0.000036856356,0.00020219233,0.000044694378,0.0015124341],"genre_scores_gemma":[0.99539113,0.0011909662,0.0012004572,0.00006401805,0.000029107707,0.000031669635,0.0001527895,0.000004561047,0.0019352947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987185,0.000028939405,0.000010398999,0.000012998413,0.00002543231,0.00005047695],"domain_scores_gemma":[0.99993944,0.000012900196,0.000015060098,0.000011240747,0.0000074006657,0.000013978921],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022085849,0.00028737087,0.00018165559,0.00023057904,0.00023333287,0.00041094297,0.00016000618,0.00031890217,0.0010916522],"category_scores_gemma":[0.00017447962,0.00013776598,0.0001722004,0.00013637754,0.0002606403,0.00033720298,0.0004229066,0.00043605146,0.0002694766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052227103,0.00005100807,0.00077284215,0.000061626604,0.000003993702,0.00063314184,0.000048556936,0.000034614684,0.99405366,0.0002896097,0.00009178984,0.0034369072],"study_design_scores_gemma":[0.00006319611,0.00044434497,0.03739518,0.000016179907,0.000022103126,0.0018903645,0.00031150598,0.0010420157,0.9549331,0.0004005091,0.0034736826,0.000007868758],"about_ca_topic_score_codex":0.0002840125,"about_ca_topic_score_gemma":0.0002832672,"teacher_disagreement_score":0.0010916522,"about_ca_system_score_codex":0.00027217952,"about_ca_system_score_gemma":0.00018563223,"threshold_uncertainty_score":0.0036519766},"labels":[],"label_agreement":null},{"id":"W2096007970","doi":"10.1111/cbdd.12381","title":"Computer‐Aided Drug Discovery Approach Finds Calcium Sensitizer of Cardiac Troponin","year":2014,"lang":"en","type":"article","venue":"Chemical Biology & Drug Design","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; National Institute for Health and Care Research; National Biomedical Computation Resource; National Institute of General Medical Sciences; American Heart Association; Center for Theoretical Biological Physics; Howard Hughes Medical Institute; National Institutes of Health; National Science Foundation","keywords":"Calcium; Troponin I; Troponin C; Drug discovery; Chemistry; Troponin; Drug; Virtual screening; Biophysics; Combinatorial chemistry; Pharmacology; Biochemistry; Cardiology; Medicine; Biology","score_opus":0.014254127138461197,"score_gpt":0.2385308332588377,"score_spread":0.2242767061203765,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096007970","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.32920504,0.007587906,0.60543513,0.0024507109,0.00025930238,0.0006950239,0.003497032,0.007348029,0.04352191],"genre_scores_gemma":[0.68696827,0.0021055543,0.29978463,0.0005257381,0.000044770983,0.00064495765,0.002567632,0.00014637342,0.0072119916],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99987614,0.00003745718,0.0000059288136,0.000025526482,0.00003495487,0.00002001715],"domain_scores_gemma":[0.999819,0.000121239915,0.000013960278,0.0000053054796,0.000030988187,0.000009566298],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036416593,0.0007234553,0.0011057646,0.00081005227,0.00030419047,0.0007812093,0.0006774385,0.0007334841,0.0045272564],"category_scores_gemma":[0.00069494697,0.00030363761,0.0008184696,0.0005968943,0.00017849736,0.00025391203,0.00036860266,0.00054123387,0.00043187846],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043229657,0.00033953824,0.0032089252,0.00052381813,0.00024932658,0.00040950996,0.000057220062,0.8530825,0.010528883,0.009542214,0.00517623,0.11644965],"study_design_scores_gemma":[0.000073245705,0.000082475046,0.00019670292,0.000009381648,0.000040756877,0.000034316214,0.00001144266,0.9948809,0.0013922983,0.0012653219,0.0020079615,0.0000052245327],"about_ca_topic_score_codex":0.0071522607,"about_ca_topic_score_gemma":0.009965484,"teacher_disagreement_score":0.0071522607,"about_ca_system_score_codex":0.00051429216,"about_ca_system_score_gemma":0.0015584454,"threshold_uncertainty_score":0.015145242},"labels":[],"label_agreement":null},{"id":"W2096275987","doi":"10.1074/jbc.m002595200","title":"Structure of a Conserved Domain Common to the Transcription Factors TFIIS, Elongin A, and CRSP70","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Transcription factor; Domain (mathematical analysis); Transcription (linguistics); Computational biology; Biology; Genetics; Evolutionary biology; Gene; Mathematics","score_opus":0.015145606579068284,"score_gpt":0.24178734990077225,"score_spread":0.22664174332170398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2096275987","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824363,0.0028313566,0.010357013,0.0001966429,0.000055187196,0.000056384713,0.00082066865,0.00023522238,0.0030113147],"genre_scores_gemma":[0.9921685,0.0005546149,0.0040455014,0.00006830769,0.000010995259,0.000015655383,0.001285044,0.000010835463,0.0018405309],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99996674,0.0000034716259,0.0000017427387,0.000011210115,0.000009702573,0.0000071068116],"domain_scores_gemma":[0.99993205,0.0000062774334,0.00001730203,0.0000052311148,0.000013607394,0.000025587036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006211266,0.0002761558,0.00027982573,0.00015732521,0.00028252386,0.0003211633,0.0003240303,0.00026717543,0.0010027675],"category_scores_gemma":[0.00015179286,0.00013230993,0.0002488507,0.00021993744,0.00019428854,0.0001888909,0.00016401819,0.00040403023,0.00040030014],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063494104,0.0001158087,0.0028808268,0.0002611141,0.00005325247,0.0011484247,0.00015504308,0.009405212,0.96713287,0.003315745,0.001326792,0.013570047],"study_design_scores_gemma":[0.00053334766,0.0015865539,0.10811725,0.00017134305,0.00032248077,0.00464752,0.000846095,0.11128847,0.6698569,0.0058170897,0.096613385,0.000199649],"about_ca_topic_score_codex":0.00328835,"about_ca_topic_score_gemma":0.0022058715,"teacher_disagreement_score":0.00328835,"about_ca_system_score_codex":0.0005756552,"about_ca_system_score_gemma":0.00045662682,"threshold_uncertainty_score":0.0065384507},"labels":[],"label_agreement":null},{"id":"W2099555445","doi":"10.4049/jimmunol.167.5.2700","title":"Negative Regulation of the NFAT1 Factor by CD45: Implication in HIV-1 Long Terminal Repeat Activation","year":2001,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval; Centre hospitalier universitaire de Québec","funders":"Medical Research Council; Canadian Institutes of Health Research; Medical Research Council Canada","keywords":"NFAT; Jurkat cells; Cell biology; Molecular biology; Biology; Transcription factor; Chemistry; T cell; Gene; Genetics; Immune system","score_opus":0.009820402621826112,"score_gpt":0.2498161239738525,"score_spread":0.23999572135202638,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099555445","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948159,0.002940761,0.0013719706,0.00004718392,0.000013534518,0.000009666368,0.000088732384,0.000022247948,0.0006900587],"genre_scores_gemma":[0.99811965,0.0006962228,0.0005107528,0.000023869487,0.0000060839766,0.000006448631,0.000114695096,0.000004428729,0.0005177676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998783,0.00001980496,0.000010599638,0.000022941598,0.000030818348,0.000037415735],"domain_scores_gemma":[0.9999014,0.000014623236,0.00003940735,0.000009537862,0.000011570172,0.000023440805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011125126,0.0002560401,0.00013907612,0.00012211053,0.00010507017,0.0004251589,0.00013525446,0.00019329258,0.00074042834],"category_scores_gemma":[0.0001067072,0.00009336843,0.00013726037,0.000109399305,0.00018265184,0.0001658445,0.00015392846,0.00019885806,0.00015011756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000043451637,0.000007700812,0.0002814996,0.0000171263,0.0000012087719,0.000045499288,0.0000069468933,0.000007123139,0.9991196,0.000047910027,0.000004984855,0.00041691278],"study_design_scores_gemma":[0.000011521628,0.00010792383,0.016589696,0.0000071743557,0.000012042041,0.00060950685,0.000032117532,0.0004662385,0.9810342,0.00007609455,0.0010497227,0.000003714723],"about_ca_topic_score_codex":0.00031503028,"about_ca_topic_score_gemma":0.00028124594,"teacher_disagreement_score":0.00074042834,"about_ca_system_score_codex":0.0001689022,"about_ca_system_score_gemma":0.000106630214,"threshold_uncertainty_score":0.0024769902},"labels":[],"label_agreement":null},{"id":"W2099744865","doi":"10.1091/mbc.02-02-0016","title":"p38 Mitogen-activated Protein Kinase-, Calcium-Calmodulin–dependent Protein Kinase-, and Calcineurin-mediated Signaling Pathways Transcriptionally Regulate Myogenin Expression","year":2002,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Western University","funders":"Hong Kong University of Science and Technology; University Grants Committee","keywords":"Biology; Mef2; Cell biology; Myogenin; Protein kinase A; MyoD; Myogenic regulatory factors; c-Raf; CAMK; Signal transduction; ASK1; Calcineurin; Mitogen-activated protein kinase kinase; MAP kinase kinase kinase; Molecular biology; Transcription factor; Kinase; Enhancer; Biochemistry; Myocyte; Myogenesis","score_opus":0.016879913795771306,"score_gpt":0.22026474715493072,"score_spread":0.2033848333591594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2099744865","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9768984,0.005354329,0.011767448,0.00030472004,0.000081428836,0.000078750985,0.00038817414,0.00018029082,0.004946401],"genre_scores_gemma":[0.98387825,0.00203856,0.0057939603,0.00008006367,0.000028627814,0.00008521562,0.00045428917,0.000016718965,0.0076242182],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998573,0.000017351233,0.00000772395,0.000032691496,0.000049958227,0.000034995475],"domain_scores_gemma":[0.9999269,0.000009129124,0.000019872485,0.000010993022,0.000011666778,0.000021395468],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014235392,0.00049363676,0.00015131928,0.00019235951,0.00026821523,0.00022561113,0.00022278354,0.00020365481,0.0014494399],"category_scores_gemma":[0.00010455644,0.000116179726,0.00026621073,0.00009061625,0.00022443969,0.00023326681,0.00035860017,0.000374079,0.00040526516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046106023,0.000012310092,0.00050370494,0.000032290158,0.000003817575,0.00006191394,0.00001680999,0.000038012975,0.99689853,0.0002445521,0.000031515814,0.0021105225],"study_design_scores_gemma":[0.00002559851,0.00014332586,0.020078506,0.000013364862,0.000017458766,0.00044930537,0.00005194935,0.0013596674,0.97087514,0.00027961878,0.00670073,0.000005390605],"about_ca_topic_score_codex":0.0005454781,"about_ca_topic_score_gemma":0.0015806637,"teacher_disagreement_score":0.0014494399,"about_ca_system_score_codex":0.00038266034,"about_ca_system_score_gemma":0.0003676027,"threshold_uncertainty_score":0.004848838},"labels":[],"label_agreement":null},{"id":"W2103768648","doi":"10.1034/j.1600-6143.2001.10407.x","title":"Tissue Distribution of Calcineurin and its Sensitivity to Inhibition by Cyclosporine","year":2001,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":72,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Calcineurin; Kidney; In vivo; Spleen; In vitro; Medicine; Endocrinology; Pharmacology; Internal medicine; Biology; Transplantation; Biochemistry","score_opus":0.0051892263769953645,"score_gpt":0.2506128229313826,"score_spread":0.24542359655438722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103768648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97543204,0.011888922,0.004235392,0.00035433075,0.00011762823,0.000025829566,0.0004839953,0.00014680915,0.00731509],"genre_scores_gemma":[0.993616,0.0021101623,0.00084222795,0.000046084202,0.000056602374,0.00002263973,0.00039367343,0.000037614263,0.0028749555],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99968314,0.00007283642,0.000020477088,0.000053282518,0.000059316077,0.00011094857],"domain_scores_gemma":[0.99947256,0.00016063542,0.000080174716,0.00007859956,0.000056539757,0.00015143122],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034309435,0.00028716822,0.000479067,0.00063687796,0.00032673936,0.00080622075,0.0004781042,0.00047086435,0.002453678],"category_scores_gemma":[0.0004707851,0.00033137592,0.00039991437,0.00052972935,0.00061062403,0.0008901224,0.00023499441,0.0018537712,0.000508936],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018242744,0.00006702026,0.00047037797,0.0000449205,0.000019000881,0.00010898171,0.00004317071,0.00014265021,0.9939606,0.0006241565,0.000079966194,0.0026149037],"study_design_scores_gemma":[0.00004496972,0.00078700605,0.018209537,0.0000107377755,0.000071900344,0.00095589453,0.00013458513,0.0018027413,0.9756614,0.00023884549,0.0020677825,0.000014560181],"about_ca_topic_score_codex":0.0015728208,"about_ca_topic_score_gemma":0.0016681969,"teacher_disagreement_score":0.002453678,"about_ca_system_score_codex":0.0005541761,"about_ca_system_score_gemma":0.00050195114,"threshold_uncertainty_score":0.008208394},"labels":[],"label_agreement":null},{"id":"W2103985017","doi":"10.18632/oncotarget.3528","title":"FKBPL: a marker of good prognosis in breast cancer","year":2015,"lang":"en","type":"review","venue":"Oncotarget","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Biotechnology and Biological Sciences Research Council","keywords":"Medicine; Hazard ratio; Breast cancer; Internal medicine; Tamoxifen; Tissue microarray; Confidence interval; Oncology; Immunohistochemistry; Estrogen receptor; Univariate analysis; Cancer; Gynecology; Multivariate analysis","score_opus":0.03453066698489678,"score_gpt":0.34498607368613426,"score_spread":0.3104554067012375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2103985017","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.91155446,0.046372384,0.001463435,0.00919269,0.00074967503,0.00009734513,0.0049311584,0.0003063926,0.025332531],"genre_scores_gemma":[0.9888685,0.003930029,0.0009618517,0.0008174784,0.00033777216,0.00004641597,0.0017797227,0.000019821358,0.0032384805],"study_design_codex":"observational","study_design_gemma":"not_applicable","domain_scores_codex":[0.99969316,0.00006556546,0.000024149878,0.00006031022,0.00008939219,0.000067425564],"domain_scores_gemma":[0.99898523,0.00016962527,0.00042633564,0.000042658616,0.00016944016,0.00020669645],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00064860965,0.00041020595,0.0005041026,0.0012237232,0.00049416145,0.001383885,0.00032790456,0.00071700854,0.003346477],"category_scores_gemma":[0.0031376518,0.00014505823,0.00023963612,0.0009523165,0.00030807478,0.00044011598,0.0006556938,0.00067744695,0.0015739683],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0029615804,0.00006651435,0.85006666,0.00020863279,0.00011028389,0.00044902094,0.00010680439,0.0003558071,0.0029235128,0.0002471216,0.020028295,0.12247582],"study_design_scores_gemma":[0.00006213973,0.0003171274,0.9844259,0.0001671678,0.00016517424,0.0019340332,0.0002146471,0.001433673,0.00095451175,0.00086104387,0.00942072,0.00004386907],"about_ca_topic_score_codex":0.0041507115,"about_ca_topic_score_gemma":0.0071303993,"teacher_disagreement_score":0.0041507115,"about_ca_system_score_codex":0.0009755535,"about_ca_system_score_gemma":0.00036835604,"threshold_uncertainty_score":0.011195064},"labels":[],"label_agreement":null},{"id":"W2104686479","doi":"10.25011/cim.v36i6.20625","title":"Clinical Significance of Leukotriene B4 and Extracellular Matrix Metalloproteinase Inducer in Acute Coronary Syndrome","year":2013,"lang":"en","type":"article","venue":"Clinical and investigative medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Natural Science Foundation of Zhejiang Province","keywords":"Leukotriene B4; Medicine; Unstable angina; Matrix metalloproteinase; Myocardial infarction; Acute coronary syndrome; Zymography; Metalloproteinase; Flow cytometry; Internal medicine; Extracellular matrix; Inflammation; Immunology; Chemistry; Biochemistry","score_opus":0.08754466181916029,"score_gpt":0.3456189972299976,"score_spread":0.25807433541083735,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2104686479","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.997207,0.0018011583,0.0001280578,0.00014063378,0.000012020003,0.000012910446,0.000087189364,0.0000056964727,0.00060527417],"genre_scores_gemma":[0.9992385,0.00028036762,0.00011442969,0.000047870144,0.000050676423,0.00000908126,0.00012286715,9.4580264e-7,0.00013529483],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9996935,0.00009154963,0.00005223051,0.00004820473,0.00007037653,0.00004410868],"domain_scores_gemma":[0.9992817,0.00014899208,0.00031937327,0.000020449334,0.00007033332,0.00015921787],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031981315,0.0002914976,0.00040871216,0.0005903178,0.00034943342,0.00033837583,0.00019522743,0.0005265481,0.0015485317],"category_scores_gemma":[0.001183255,0.00011988905,0.00025893422,0.0004988731,0.00032262685,0.0002056924,0.0002360782,0.00048854307,0.0002400292],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011327264,0.00005708284,0.99047804,0.00004215263,0.00003842014,0.0017837548,0.000048237842,0.000037052807,0.0031962225,0.000031644533,0.00009704647,0.00305766],"study_design_scores_gemma":[0.00003335036,0.000273435,0.99562573,0.000012059961,0.00004283263,0.0030952923,0.00007409608,0.00017755547,0.00040675385,0.000048940055,0.00020632497,0.000003696951],"about_ca_topic_score_codex":0.0004811601,"about_ca_topic_score_gemma":0.00049611233,"teacher_disagreement_score":0.0015485317,"about_ca_system_score_codex":0.00026668096,"about_ca_system_score_gemma":0.00021226286,"threshold_uncertainty_score":0.005180359},"labels":[],"label_agreement":null},{"id":"W2105320772","doi":"10.1093/emboj/cdg570","title":"Nogo‐A at CNS paranodes is a ligand of Caspr: possible regulation of K+ channel localization","year":2003,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Institute of Molecular and Cell Biology; National Medical Research Council; National Institute of Neurological Disorders and Stroke; Medical Research Council; Canadian Institutes of Health Research; European Commission; Singapore General Hospital; Agency for Science, Technology and Research; National Institutes of Health; National University of Singapore; Yale University","keywords":"Biology; Channel (broadcasting); Ligand (biochemistry); Neuroscience; Computational biology; Cell biology; Genetics; Computer science; Receptor; Computer network","score_opus":0.01589592950294978,"score_gpt":0.24968166034566058,"score_spread":0.23378573084271081,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105320772","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98823893,0.002427932,0.0064108814,0.00031275695,0.000038975217,0.000012363821,0.00014892119,0.00006190672,0.0023473084],"genre_scores_gemma":[0.99605715,0.0005097815,0.001686413,0.00004612206,0.000008868425,0.000015741494,0.00010001586,0.000016982916,0.0015588739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985003,0.000032912234,0.000009965385,0.00002545551,0.000025615189,0.000055992485],"domain_scores_gemma":[0.99983025,0.000031154,0.000041799885,0.0000137518655,0.000022289616,0.000060701197],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021598011,0.00037567722,0.00026710946,0.00024307221,0.00044771857,0.0006076692,0.00058669073,0.000551565,0.0014102658],"category_scores_gemma":[0.00030960355,0.00016496726,0.00032593418,0.0001016561,0.0004481934,0.00076645747,0.00050698087,0.0005658263,0.00040167628],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000286368,0.000006149024,0.00033758782,0.000044988785,0.000007866537,0.0006520646,0.000031118125,0.000100661615,0.9967104,0.0009882438,0.000038602207,0.0007960222],"study_design_scores_gemma":[0.00004273402,0.00027789728,0.0134206265,0.000023814344,0.000059369024,0.002714558,0.00037979204,0.0021981695,0.97609496,0.0016208965,0.0031439268,0.000023197617],"about_ca_topic_score_codex":0.0006591813,"about_ca_topic_score_gemma":0.00082980783,"teacher_disagreement_score":0.0014102658,"about_ca_system_score_codex":0.0005042177,"about_ca_system_score_gemma":0.00027224675,"threshold_uncertainty_score":0.004717827},"labels":[],"label_agreement":null},{"id":"W2106366918","doi":"10.2174/1567205010666131212114907","title":"Regulator of Calcineurin 1 Gene Transcription is Regulated by Nuclear Factor-kappaB","year":2014,"lang":"en","type":"article","venue":"Current Alzheimer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"NFAT; Transcription factor; Gene isoform; Biology; Electrophoretic mobility shift assay; Gene expression; Transcription (linguistics); Regulation of gene expression; Response element; Molecular biology; TCF4; Calcineurin; Cell biology; Promoter; Gene; Enhancer; Genetics","score_opus":0.10436319005665819,"score_gpt":0.3765793896442407,"score_spread":0.27221619958758253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2106366918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.957801,0.02221322,0.009772386,0.00038824705,0.00019306784,0.00008353959,0.0010075746,0.00056389417,0.007977141],"genre_scores_gemma":[0.98400545,0.004795581,0.003097574,0.00011466201,0.0000405465,0.00008212393,0.000826091,0.000039426573,0.0069985054],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978536,0.000025619516,0.0000129668315,0.00007374998,0.0000641125,0.000038132654],"domain_scores_gemma":[0.99984145,0.000022184466,0.000060968232,0.0000140151515,0.00003621834,0.000025016754],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017073582,0.0005300124,0.00020915593,0.00039443158,0.00032971395,0.00041629325,0.00020667554,0.0001942189,0.0017009984],"category_scores_gemma":[0.00021118025,0.00013635634,0.00035795567,0.00024283431,0.0003003259,0.00016451471,0.00024125188,0.00040433343,0.00040492514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013842362,0.00003135953,0.0012147885,0.000101027574,0.0000127267695,0.00016805595,0.000055902652,0.00009540109,0.99389714,0.00026667555,0.00015982223,0.003858687],"study_design_scores_gemma":[0.00007696326,0.00032278048,0.06345119,0.00007293743,0.000070183654,0.0011770877,0.00018442888,0.0036615017,0.90562177,0.00079766824,0.024532666,0.000030748994],"about_ca_topic_score_codex":0.0014330727,"about_ca_topic_score_gemma":0.0014243,"teacher_disagreement_score":0.0017009984,"about_ca_system_score_codex":0.00054519606,"about_ca_system_score_gemma":0.00036858313,"threshold_uncertainty_score":0.005690396},"labels":[],"label_agreement":null},{"id":"W2107726672","doi":"10.1371/journal.pone.0011969","title":"Transgenic Overexpression of Active Calcineurin in β-Cells Results in Decreased β-Cell Mass and Hyperglycemia","year":2010,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institutes of Health; American Diabetes Association","keywords":"Calcineurin; NFAT; Glucose homeostasis; Endocrinology; Beta cell; Internal medicine; Biology; Cell biology; Insulin; Insulin resistance; Islet; Transplantation; Medicine","score_opus":0.016300172443661973,"score_gpt":0.2228342472860364,"score_spread":0.20653407484237443,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2107726672","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98782897,0.001474189,0.0073960447,0.00016750286,0.000115109964,0.0000809797,0.0008685949,0.00048247885,0.0015861174],"genre_scores_gemma":[0.98004365,0.0018641072,0.009417614,0.00016116755,0.00006242667,0.00015677098,0.0018233223,0.00032591782,0.006145057],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999584,0.000031020994,0.00006585332,0.00011523862,0.00014089631,0.00006294948],"domain_scores_gemma":[0.9992669,0.000089966816,0.00033639296,0.00007147072,0.00004403116,0.00019115505],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033196973,0.0008242088,0.00044341496,0.00052954635,0.00022356724,0.00063617725,0.00058076053,0.0006503022,0.002215034],"category_scores_gemma":[0.0002441646,0.0003007012,0.0004302785,0.00038045098,0.00069412886,0.00034425635,0.00034341603,0.0012472401,0.0006119906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008252364,0.000029988381,0.0001446717,0.000021271842,0.000007358135,0.000069506124,0.000011731486,0.000027808506,0.99918693,0.00007325797,0.000021466463,0.00032342234],"study_design_scores_gemma":[0.00006877057,0.00030036233,0.004195268,0.000020915575,0.000073015966,0.00084272004,0.00003715053,0.0008692781,0.9910986,0.00007973076,0.0024043783,0.00000973835],"about_ca_topic_score_codex":0.00040895064,"about_ca_topic_score_gemma":0.0005391789,"teacher_disagreement_score":0.002215034,"about_ca_system_score_codex":0.00045622542,"about_ca_system_score_gemma":0.00032186494,"threshold_uncertainty_score":0.00740999},"labels":[],"label_agreement":null},{"id":"W2109268312","doi":"10.1161/hypertensionaha.113.02083","title":"Interferon Regulatory Factor 9 Protects Against Cardiac Hypertrophy by Targeting Myocardin","year":2013,"lang":"en","type":"article","venue":"Hypertension","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Myocardin; Muscle hypertrophy; Pressure overload; Serum response factor; Fibrosis; Cardiac hypertrophy; Transcription factor; Internal medicine; Endocrinology; Cardiac fibrosis; Heart failure; Medicine; Biology; Cell biology; Cancer research; Biochemistry; Gene","score_opus":0.009039236916994563,"score_gpt":0.1934293408401448,"score_spread":0.18439010392315022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2109268312","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99271977,0.0019442817,0.0033930843,0.0002783875,0.00010787971,0.000032290875,0.00016215388,0.00015265871,0.0012094124],"genre_scores_gemma":[0.9953246,0.0010560264,0.0019024101,0.00011118227,0.00004705276,0.000025502291,0.000282098,0.00001926654,0.0012316747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990547,0.000022482285,0.000009257684,0.00001598183,0.000017634637,0.00002914745],"domain_scores_gemma":[0.99992406,0.000011250999,0.000020019848,0.000010663932,0.000007142723,0.000026830094],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022593234,0.00035718252,0.00031100164,0.00020063577,0.00012993836,0.00018806082,0.00023824259,0.00026718792,0.0010072825],"category_scores_gemma":[0.00009757611,0.00010985761,0.00020156766,0.000068823356,0.00021210103,0.0001701191,0.00014104802,0.0007833843,0.00027690982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002957953,0.0001031826,0.0001623281,0.000024530791,0.0000061450983,0.000031631334,0.000005406903,0.000028759954,0.9968485,0.00006607813,0.000049872346,0.00237779],"study_design_scores_gemma":[0.00022315563,0.0026190565,0.0064156326,0.000017130093,0.00004879723,0.0003444075,0.00003326324,0.0010016548,0.9860773,0.00017840553,0.0030319628,0.000009289802],"about_ca_topic_score_codex":0.00010686637,"about_ca_topic_score_gemma":0.00023641247,"teacher_disagreement_score":0.0010072825,"about_ca_system_score_codex":0.00011026334,"about_ca_system_score_gemma":0.00013332324,"threshold_uncertainty_score":0.003369689},"labels":[],"label_agreement":null},{"id":"W2110239305","doi":"10.1161/jaha.114.000965","title":"Reducing Endoglin Activity Limits Calcineurin and TRPC‐6 Expression and Improves Survival in a Mouse Model of Right Ventricular Pressure Overload","year":2014,"lang":"en","type":"article","venue":"Journal of the American Heart Association","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; Heart and Stroke Foundation; University of Toronto","funders":"National Heart, Lung, and Blood Institute","keywords":"Myofibroblast; TRPC; Calcineurin; Endoglin; Fibrosis; Pressure overload; Medicine; Cardiac fibrosis; Internal medicine; Biology; Receptor; Cell biology; Heart failure; Transplantation; Transient receptor potential channel; Stem cell","score_opus":0.009329855726489526,"score_gpt":0.24804626155590465,"score_spread":0.2387164058294151,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110239305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921653,0.001653175,0.003710657,0.00036637747,0.00011749197,0.000068741654,0.00080821273,0.0003032972,0.00080670335],"genre_scores_gemma":[0.98376125,0.0017948096,0.0061301226,0.000277969,0.00005468441,0.00027223406,0.0013125974,0.00011511647,0.0062811617],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996731,0.00004199204,0.00004809253,0.000073538664,0.00008810984,0.00007520115],"domain_scores_gemma":[0.99956053,0.000042713153,0.00017050964,0.000039246625,0.000027994665,0.00015896247],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032942486,0.0010503713,0.00066298177,0.00064254313,0.00020510916,0.00037802657,0.00059072115,0.0009077187,0.001677792],"category_scores_gemma":[0.00014854711,0.00028795452,0.0005266821,0.00020148541,0.00062489597,0.00050436455,0.00026451235,0.0017013947,0.00050484505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004742382,0.00020578997,0.00014160108,0.000049392558,0.000009818261,0.00006296509,0.000012485656,0.000074840886,0.9978782,0.000080964055,0.000058219142,0.00095143204],"study_design_scores_gemma":[0.00027130978,0.003985507,0.004183463,0.000024903515,0.000085309955,0.000497943,0.00004824768,0.0014320266,0.9873553,0.000104079314,0.0019986413,0.00001327753],"about_ca_topic_score_codex":0.00029677537,"about_ca_topic_score_gemma":0.00055582763,"teacher_disagreement_score":0.001677792,"about_ca_system_score_codex":0.00029505245,"about_ca_system_score_gemma":0.00026893144,"threshold_uncertainty_score":0.005612731},"labels":[],"label_agreement":null},{"id":"W2110243086","doi":"10.1261/rna.042648.113","title":"The prolyl isomerase, FKBP25, interacts with RNA-engaged nucleolin and the pre-60S ribosomal subunit","year":2014,"lang":"en","type":"article","venue":"RNA","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Cancer Society Research Institute","keywords":"Ribosome biogenesis; Biology; Ribosomal protein; Nucleolin; Eukaryotic Ribosome; Ribosome; Prolyl isomerase; Ribosomal RNA; Protein subunit; Eukaryotic Large Ribosomal Subunit; Chaperone (clinical); Biochemistry; FKBP; Chromatin; Cell biology; RNA; Isomerase; Nucleolus; Enzyme; Cytoplasm; DNA; Gene","score_opus":0.00553051314894309,"score_gpt":0.21214782132018026,"score_spread":0.20661730817123716,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110243086","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848622,0.0071618366,0.0052476455,0.00013289203,0.000048778944,0.00002073815,0.00032181857,0.00010427006,0.00209991],"genre_scores_gemma":[0.99300534,0.0009424327,0.0020632027,0.00006482525,0.000011058525,0.000012130354,0.00051110575,0.0000120362865,0.003377905],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984205,0.000015991594,0.000008555489,0.000063105676,0.00003245776,0.00003782993],"domain_scores_gemma":[0.99992216,0.000011920962,0.00002615821,0.0000067072037,0.000006162923,0.000026920594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000812374,0.00047831502,0.00026709496,0.00037248354,0.00041312998,0.00037954212,0.00020005791,0.00038305874,0.0012725221],"category_scores_gemma":[0.0001663835,0.00017217496,0.00038860584,0.00017625676,0.00021180375,0.0002063707,0.0002158893,0.00026303134,0.0005922243],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009194313,0.000011878954,0.0007388789,0.00004053208,0.000016895961,0.00019533798,0.000011067873,0.000049139137,0.99682826,0.00008549699,0.0000790865,0.0018513569],"study_design_scores_gemma":[0.000010825483,0.00012117521,0.05225792,0.000017411787,0.000058860747,0.0014610619,0.000054594515,0.0013443704,0.9376636,0.000110879046,0.006882408,0.000016742213],"about_ca_topic_score_codex":0.0024992716,"about_ca_topic_score_gemma":0.0033273643,"teacher_disagreement_score":0.0024992716,"about_ca_system_score_codex":0.00073338975,"about_ca_system_score_gemma":0.00020545522,"threshold_uncertainty_score":0.005321145},"labels":[],"label_agreement":null},{"id":"W2110288122","doi":"10.1091/mbc.e07-03-0237","title":"Inhibition of Pin1 Reduces Glutamate-induced Perikaryal Accumulation of Phosphorylated Neurofilament-H in Neurons","year":2007,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"National Institute of Mental Health; National Institutes of Health","keywords":"PIN1; Phosphorylation; Biology; Peptidylprolyl isomerase; Kinase; Serine; Neurofilament; Prolyl isomerase; Threonine; Cell biology; Neurodegeneration; Biochemistry; Glutamate receptor; Phosphatase; Isomerase; Enzyme","score_opus":0.022159677619393324,"score_gpt":0.2983815857258713,"score_spread":0.276221908106478,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2110288122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99509144,0.001896564,0.0010163801,0.000105278334,0.000048495483,0.000038283993,0.0004167748,0.00017891088,0.0012079808],"genre_scores_gemma":[0.9952931,0.0014645857,0.00085420045,0.00005951162,0.000011023082,0.00006257789,0.0005604519,0.000022042224,0.001672409],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989665,0.000009439724,0.000010603331,0.000017380764,0.000023037985,0.000042936328],"domain_scores_gemma":[0.9999107,0.000012446241,0.000023159402,0.000006790889,0.0000075965395,0.00003934437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010364676,0.0005980634,0.00047792675,0.00024888583,0.00016162114,0.00028113255,0.00035253185,0.00035241494,0.001549261],"category_scores_gemma":[0.00011619236,0.00017260548,0.00028237686,0.00017449692,0.00026469977,0.00026564964,0.0002316491,0.0007739257,0.00035124415],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052552397,0.00010942685,0.000119759934,0.0001355322,0.000013034434,0.0000610662,0.000018863328,0.000121373785,0.99728036,0.000070814596,0.00007262165,0.0014715384],"study_design_scores_gemma":[0.00003657947,0.0009622726,0.0032440966,0.000010241541,0.00002372885,0.000114650764,0.0000365423,0.0007139929,0.9939085,0.0000430919,0.00089988275,0.0000063555703],"about_ca_topic_score_codex":0.0005582306,"about_ca_topic_score_gemma":0.0008407948,"teacher_disagreement_score":0.001549261,"about_ca_system_score_codex":0.00031202595,"about_ca_system_score_gemma":0.00029812893,"threshold_uncertainty_score":0.0051828623},"labels":[],"label_agreement":null},{"id":"W2111868411","doi":"10.1074/jbc.m112.339788","title":"FK506 Binding Protein 8 Peptidylprolyl Isomerase Activity Manages a Late Stage of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Folding and Stability","year":2012,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Institute on Aging; Canadian Institutes of Health Research","keywords":"Cystic fibrosis transmembrane conductance regulator; ΔF508; Proteostasis; Endoplasmic reticulum; Cell biology; Biology; Protein disulfide-isomerase; Cystic fibrosis; Chemistry; Genetics","score_opus":0.02763703615525057,"score_gpt":0.2593603586096761,"score_spread":0.23172332245442553,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2111868411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902653,0.0048880484,0.002924761,0.00022762535,0.00004816373,0.000008792674,0.00019786018,0.00010877438,0.0013306183],"genre_scores_gemma":[0.99678314,0.0010068731,0.0010826639,0.000027570908,0.0000074400677,0.0000041960125,0.00015642507,0.0000055404535,0.0009261482],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999511,0.0000076044653,0.000003039511,0.000012291203,0.000010263125,0.000015744876],"domain_scores_gemma":[0.9999639,0.0000029475361,0.00001144866,0.0000022772429,0.0000037396837,0.000015698777],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005792565,0.00022504847,0.0002059968,0.00010940224,0.0001766102,0.00018102465,0.000115414965,0.0002213518,0.000773672],"category_scores_gemma":[0.00006921873,0.000055633307,0.000102065795,0.0000679906,0.00015824885,0.00015571338,0.00012782351,0.0002605968,0.00029403646],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015760698,0.00000825707,0.00036611993,0.000019343284,0.0000029940027,0.00007993519,0.0000057478514,0.000049680384,0.99749255,0.000109667766,0.00006157268,0.0016466625],"study_design_scores_gemma":[0.00002144524,0.00034725686,0.028209351,0.000009718739,0.00002792112,0.0012975665,0.00004752379,0.0015426377,0.9625226,0.00022487827,0.0057384586,0.000010612367],"about_ca_topic_score_codex":0.000507077,"about_ca_topic_score_gemma":0.00070405734,"teacher_disagreement_score":0.000773672,"about_ca_system_score_codex":0.00022786202,"about_ca_system_score_gemma":0.00012298708,"threshold_uncertainty_score":0.002588153},"labels":[],"label_agreement":null},{"id":"W2112109945","doi":"10.1128/jvi.02107-14","title":"Inhibition of Breast Cancer Cell Proliferation through Disturbance of the Calcineurin/NFAT Pathway by Human Herpesvirus 6B U54 Tegument Protein","year":2014,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; Centre hospitalier universitaire de Québec","funders":"Canadian Institutes of Health Research","keywords":"NFAT; Calcineurin; Biology; Cell biology; Cell growth; Cancer research; Cancer cell; Cancer; Transplantation; Biochemistry; Internal medicine; Medicine","score_opus":0.006306331646867813,"score_gpt":0.23838409932399932,"score_spread":0.2320777676771315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112109945","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9881995,0.008954002,0.000952294,0.00013033958,0.000030633895,0.000017881277,0.000122005615,0.000039082526,0.0015542903],"genre_scores_gemma":[0.9940896,0.003605186,0.0009878976,0.000035659832,0.000009928156,0.00001867623,0.00014870966,0.0000048095712,0.0010996355],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999386,0.000011570117,0.0000060392113,0.000007095925,0.000015185907,0.000021474234],"domain_scores_gemma":[0.99997556,0.0000058376595,0.000005748471,0.000004105438,0.000003152267,0.000005718589],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008195425,0.00018483496,0.00015956846,0.00011827731,0.00012247238,0.00013378002,0.000116954696,0.00012315548,0.00066623604],"category_scores_gemma":[0.00006377298,0.000046386464,0.0001573282,0.000085622516,0.00012007543,0.00009622529,0.0001015106,0.00032438143,0.00011637132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013653642,0.000052279916,0.00018817477,0.00005917473,0.0000068993204,0.0000330906,0.000011292091,0.0000584415,0.99531037,0.00012981366,0.000044390385,0.003969607],"study_design_scores_gemma":[0.000014090002,0.0003603339,0.0022680326,0.000006120707,0.000013711635,0.00016833197,0.000017183751,0.00033678967,0.9941928,0.000037182657,0.0025837056,0.0000016666175],"about_ca_topic_score_codex":0.0007000557,"about_ca_topic_score_gemma":0.0010822476,"teacher_disagreement_score":0.0007000557,"about_ca_system_score_codex":0.00019796248,"about_ca_system_score_gemma":0.00021177508,"threshold_uncertainty_score":0.0022287369},"labels":[],"label_agreement":null},{"id":"W2112958265","doi":"10.1074/jbc.m302719200","title":"GATA-4 Is a Nuclear Mediator of Mechanical Stretch-activated Hypertrophic Program","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute; Université de Montréal","funders":"Sydäntutkimussäätiö; Emil Aaltosen Säätiö; Canadian Institutes of Health Research; Suomen Kulttuurirahasto; Ida Montinin Säätiö; Tekes; Finska Läkaresällskapet; Aarne Koskelon Säätiö; Foundation for Cardiovascular Research","keywords":"Mediator; Internal medicine; Medicine","score_opus":0.02273320755004649,"score_gpt":0.2633394490691328,"score_spread":0.24060624151908633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2112958265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.970883,0.010030436,0.013852918,0.00031220858,0.00012326479,0.000046269553,0.00056192983,0.0002293286,0.0039605447],"genre_scores_gemma":[0.98871124,0.0019101164,0.0035217726,0.00009882915,0.00003821816,0.00004545813,0.0006821068,0.000025097808,0.0049672932],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985015,0.000025099227,0.0000079992,0.00003962768,0.00004476273,0.00003229367],"domain_scores_gemma":[0.99991107,0.00001048033,0.000024023413,0.000008001877,0.000013622962,0.000032812386],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013541784,0.00039038385,0.00025380697,0.00018041172,0.00020791146,0.00017543299,0.00024560775,0.00021801307,0.001998114],"category_scores_gemma":[0.00012075356,0.00017507505,0.00024937515,0.000113507354,0.0002682766,0.0001393133,0.00031671216,0.00037615938,0.00039123645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011836092,0.000009670065,0.0007448364,0.000048942762,0.0000063503535,0.00007237183,0.000014875057,0.000031941618,0.9975169,0.00011724432,0.00004590675,0.001272728],"study_design_scores_gemma":[0.00012922725,0.0008905557,0.0879088,0.000069487265,0.00011550661,0.0018320013,0.00015403815,0.002789228,0.89053243,0.00094301417,0.014613958,0.000021800422],"about_ca_topic_score_codex":0.00042766143,"about_ca_topic_score_gemma":0.00054811727,"teacher_disagreement_score":0.001998114,"about_ca_system_score_codex":0.00026261664,"about_ca_system_score_gemma":0.00018806281,"threshold_uncertainty_score":0.0066844225},"labels":[],"label_agreement":null},{"id":"W2115395895","doi":"10.1084/jem.20051519","title":"Regulation of peripheral T cell activation by calreticulin","year":2006,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Leukemia and Lymphoma Society; Università di Pisa; Novartis Foundation; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Cancer Institute; National Science Foundation","keywords":"Calreticulin; Biology; Cell biology; T cell; Endoplasmic reticulum; Immune system; T-cell receptor; Immunology","score_opus":0.00672788702871329,"score_gpt":0.25130842428961564,"score_spread":0.24458053726090234,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115395895","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950087,0.0018936043,0.00189344,0.000053200692,0.0000086967675,0.000008812131,0.00009989019,0.00005830306,0.00097541354],"genre_scores_gemma":[0.99797195,0.00057780073,0.0008166403,0.000014060476,0.0000045581214,0.0000068032364,0.000072440074,0.000008473978,0.0005273252],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999144,0.000017161876,0.0000049827536,0.000024931502,0.000013888624,0.000024551247],"domain_scores_gemma":[0.99991024,0.000013624692,0.00003377596,0.000011867835,0.000009245852,0.00002120049],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000080480364,0.00020950363,0.00015580903,0.00010875816,0.00009438653,0.00029976663,0.00009547844,0.00014937692,0.00077377673],"category_scores_gemma":[0.00011137534,0.00006530433,0.00007462188,0.000091007154,0.00026726536,0.00013933257,0.00015957622,0.00026421645,0.0001794164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008317089,0.0000036316253,0.00015363579,0.000007572878,5.569517e-7,0.00002546511,0.000003671376,0.000022896327,0.99891734,0.000040249586,0.0000073453466,0.0007344227],"study_design_scores_gemma":[0.000025288728,0.00021851878,0.0126954885,0.0000062403137,0.0000090682415,0.00042900324,0.00003106002,0.0012964533,0.9837887,0.00016146759,0.0013349508,0.0000037173634],"about_ca_topic_score_codex":0.0001736577,"about_ca_topic_score_gemma":0.00020806972,"teacher_disagreement_score":0.00077377673,"about_ca_system_score_codex":0.00022478942,"about_ca_system_score_gemma":0.00009517166,"threshold_uncertainty_score":0.0025885701},"labels":[],"label_agreement":null},{"id":"W2115670666","doi":"10.1038/ja.2006.26","title":"3-Normeridamycin: A Potent Non-Immunosuppressive Immunophilin Ligand is Neuroprotective in Dopaminergic Neurons","year":2006,"lang":"en","type":"article","venue":"The Journal of Antibiotics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Neurotoxin; Neuroprotection; Dopaminergic; Chemistry; Streptomyces; Dopamine; Pharmacology; Parkinsonism; EC50; Stereochemistry; Biology; Biochemistry; In vitro; Medicine; Internal medicine; Neuroscience","score_opus":0.004616158213886698,"score_gpt":0.21555810864849007,"score_spread":0.21094195043460337,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115670666","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9944811,0.0018572094,0.0010927961,0.0001528931,0.000033141852,0.000027153494,0.00030127334,0.00006197668,0.0019924827],"genre_scores_gemma":[0.9966498,0.0005350524,0.0011657939,0.00004345585,0.000013251441,0.000022368433,0.0002951463,0.000010203813,0.0012649259],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998975,0.000027209111,0.000008840701,0.000014827644,0.000021477119,0.000030228266],"domain_scores_gemma":[0.99991715,0.000015468882,0.000017052289,0.000010603063,0.000010334475,0.000029413235],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001196806,0.00022426878,0.00024393818,0.00014388963,0.00019605867,0.00021620633,0.00014095874,0.0002903482,0.0010768223],"category_scores_gemma":[0.00015774685,0.00009130826,0.000109323395,0.00011377816,0.00018292162,0.00017821709,0.00016690786,0.00036960936,0.00025764998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036698562,0.000023360015,0.00018945186,0.00002529665,0.0000060098396,0.00011688678,0.000011278964,0.00010256034,0.99711776,0.00013133351,0.00010347164,0.0018056466],"study_design_scores_gemma":[0.00003561988,0.00038656275,0.0023717924,0.000004627519,0.000008938484,0.00042457457,0.000019764379,0.00035634643,0.99334043,0.000060102564,0.002987278,0.0000040363398],"about_ca_topic_score_codex":0.0009388228,"about_ca_topic_score_gemma":0.0019999365,"teacher_disagreement_score":0.0010768223,"about_ca_system_score_codex":0.000337334,"about_ca_system_score_gemma":0.00033179825,"threshold_uncertainty_score":0.003602326},"labels":[],"label_agreement":null},{"id":"W2115904959","doi":"10.1161/circresaha.108.175463","title":"Cellular Signaling Underlying Atrial Tachycardia Remodeling of L-type Calcium Current","year":2008,"lang":"en","type":"article","venue":"Circulation Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":197,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Calcineurin; NFAT; BAPTA; Endocrinology; Internal medicine; Medicine; Downregulation and upregulation; Calcium; Calmodulin; Atrial fibrillation; Voltage-dependent calcium channel; Tachycardia; Chemistry; Transplantation","score_opus":0.30337669411191065,"score_gpt":0.42655939530844267,"score_spread":0.12318270119653202,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2115904959","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988761,0.0053275055,0.0032409895,0.00027396122,0.00004947103,0.000025142865,0.00020901467,0.00009194879,0.002020814],"genre_scores_gemma":[0.9967933,0.0015512457,0.00065916503,0.00009191247,0.000031385236,0.000027825035,0.00013788634,0.0000064430724,0.0007007175],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987733,0.000025468686,0.000008648046,0.000024453228,0.000027484535,0.000036513396],"domain_scores_gemma":[0.99991846,0.000009236023,0.000029741319,0.0000060762122,0.000013565786,0.000022775446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013400434,0.00020391129,0.00023434307,0.00011384392,0.00016397002,0.0003564087,0.00016005257,0.00031449253,0.00047624458],"category_scores_gemma":[0.000098682045,0.000102102014,0.00023807204,0.00010695149,0.00018820954,0.00030367958,0.00018823771,0.0005072339,0.00017944444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000079816564,0.000009436939,0.00027974663,0.000020273863,0.0000023716782,0.000099112556,0.000022317101,0.000021515574,0.998665,0.00007191301,0.00003144105,0.000697188],"study_design_scores_gemma":[0.0000812149,0.0008885475,0.082239315,0.000032594402,0.00005815531,0.0016415572,0.0002756477,0.0021624956,0.9073512,0.0006466522,0.0046062195,0.000016391059],"about_ca_topic_score_codex":0.0002266748,"about_ca_topic_score_gemma":0.00026384112,"teacher_disagreement_score":0.00047624458,"about_ca_system_score_codex":0.00025412271,"about_ca_system_score_gemma":0.000119389944,"threshold_uncertainty_score":0.0018438101},"labels":[],"label_agreement":null},{"id":"W2116559251","doi":"10.1007/s00109-012-0883-2","title":"Disruption of mindin exacerbates cardiac hypertrophy and fibrosis","year":2012,"lang":"en","type":"article","venue":"Journal of Molecular Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Heart and Stroke Foundation; University of Toronto; University Health Network","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Natural Science Foundation of China","keywords":"Muscle hypertrophy; Protein kinase B; Heart failure; Internal medicine; Medicine; Fibrosis; Endocrinology; GSK3B; Pressure overload; Angiotensin II; GSK-3; Cardiac fibrosis; Phospholamban; Biology; Signal transduction; Blood pressure; Cardiac hypertrophy; Cell biology","score_opus":0.00986316871702786,"score_gpt":0.2568446279616077,"score_spread":0.24698145924457982,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2116559251","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950488,0.0006249179,0.0025331003,0.00036674194,0.0001264864,0.000023195807,0.00023041334,0.00012265657,0.0009237335],"genre_scores_gemma":[0.995395,0.0003659903,0.0016033199,0.00014529224,0.000026160898,0.000033296077,0.00015887171,0.000038290782,0.002233767],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973077,0.000054487064,0.000031872478,0.000059464357,0.00004532861,0.000078151],"domain_scores_gemma":[0.9995982,0.000046758756,0.00012864772,0.000033518474,0.000013657628,0.00017913234],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024092088,0.00061332894,0.0004973751,0.00041166128,0.00032188918,0.0004200031,0.0003594497,0.0008466778,0.00311931],"category_scores_gemma":[0.00019659386,0.00042787712,0.0003479384,0.000156085,0.0007156501,0.0003708788,0.0005060346,0.0014564929,0.0005389657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00074656727,0.00008185179,0.00019444629,0.000031120097,0.00001434276,0.00014539984,0.000012309182,0.00007579415,0.99783593,0.00018419218,0.000051198927,0.0006267502],"study_design_scores_gemma":[0.00026546264,0.0014499315,0.013756481,0.000021083815,0.000107843305,0.0014241,0.00020521897,0.00213708,0.97714365,0.00047719458,0.0029861336,0.000025859545],"about_ca_topic_score_codex":0.0002880281,"about_ca_topic_score_gemma":0.00073347293,"teacher_disagreement_score":0.00311931,"about_ca_system_score_codex":0.00031531003,"about_ca_system_score_gemma":0.00023983135,"threshold_uncertainty_score":0.010435164},"labels":[],"label_agreement":null},{"id":"W2117719145","doi":"10.1074/jbc.m800267200","title":"Calcineurin B Homologous Protein 3 Promotes the Biosynthetic Maturation, Cell Surface Stability, and Optimal Transport of the Na+/H+ Exchanger NHE1 Isoform","year":2008,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Chinese hamster ovary cell; Mutant; Sodium–hydrogen antiporter; Gene isoform; Wild type; Cell biology; Cytoplasm; Immunoprecipitation; Biology; Amino acid; Transfection; Biochemistry; Calcineurin; Molecular biology; Chemistry; Receptor; Gene","score_opus":0.022246870751369194,"score_gpt":0.22181030175040967,"score_spread":0.19956343099904048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2117719145","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9937855,0.0019702988,0.002212227,0.00014817301,0.000032214106,0.000021772286,0.0002488066,0.000105380386,0.0014755996],"genre_scores_gemma":[0.9936639,0.0007800126,0.0013427451,0.00006134812,0.0000139928925,0.000018053453,0.0006576469,0.000027992259,0.0034341589],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999012,0.000010011085,0.000007713144,0.00002439218,0.00002991809,0.000026794985],"domain_scores_gemma":[0.99990416,0.000014976084,0.000021583317,0.0000118503,0.000011904103,0.000035466226],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013953932,0.00024857186,0.00021119595,0.00019859866,0.00017503048,0.00036032972,0.00017430203,0.00022563868,0.0012229088],"category_scores_gemma":[0.000104575185,0.00009838692,0.00028125482,0.00016647267,0.00020487537,0.00017516923,0.00024830585,0.0005534305,0.0003310305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006800538,0.000016030262,0.00010028092,0.000019692661,0.0000024714088,0.000028571176,0.000008288117,0.00001941957,0.9990627,0.00008498143,0.00002727612,0.0005622327],"study_design_scores_gemma":[0.000022421424,0.000102936814,0.008844713,0.000004895242,0.000011475871,0.00024375241,0.00003015878,0.0011141859,0.98583096,0.00007756315,0.0037135582,0.000003384706],"about_ca_topic_score_codex":0.0010001274,"about_ca_topic_score_gemma":0.001707153,"teacher_disagreement_score":0.0012229088,"about_ca_system_score_codex":0.00040989518,"about_ca_system_score_gemma":0.00034135085,"threshold_uncertainty_score":0.0040910244},"labels":[],"label_agreement":null},{"id":"W2118151793","doi":"10.1016/j.ymeth.2006.07.016","title":"Chemical genetic strategies to delineate MAP kinase signaling pathways using protein-fragment complementation assays (PCA)","year":2006,"lang":"en","type":"review","venue":"Methods","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Protein-fragment complementation assay; Kinase; Effector; Complementation; Signal transduction; Biology; Cell biology; Computational biology; Mitogen-activated protein kinase; Protein kinase A; MAPK/ERK pathway; MAPKAPK2; MAP kinase kinase kinase; Biochemistry; Phenotype; Gene","score_opus":0.12487395750140833,"score_gpt":0.4372686918776953,"score_spread":0.31239473437628695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118151793","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.007202184,0.8117289,0.161993,0.0017278697,0.0012928238,0.0003962395,0.0010378852,0.0012183882,0.013402718],"genre_scores_gemma":[0.025720907,0.84667337,0.11109316,0.0009793629,0.0002728956,0.00057730085,0.002007779,0.00011341079,0.01256173],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99948287,0.000061604296,0.00003207656,0.00011472356,0.00026150022,0.000047164966],"domain_scores_gemma":[0.999438,0.0002616988,0.0000747145,0.00004818496,0.00013366087,0.000043775857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0013500109,0.0026648296,0.001704983,0.002988008,0.00044252674,0.0011586242,0.0022039004,0.0012097579,0.0017902368],"category_scores_gemma":[0.0006628263,0.0007763377,0.0007302737,0.0023157925,0.0016941073,0.0010407289,0.00069676666,0.0037950936,0.0029652582],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002586906,0.00047046068,0.000294843,0.006367819,0.00009455296,0.00039719927,0.000064301064,0.001388911,0.45149523,0.01722185,0.018837066,0.50310904],"study_design_scores_gemma":[0.00013207781,0.00032563898,0.0014791653,0.00044867562,0.00017138234,0.0029207424,0.000059036414,0.0014105581,0.45612493,0.0059229336,0.53089046,0.000114437324],"about_ca_topic_score_codex":0.0015304091,"about_ca_topic_score_gemma":0.0020654504,"teacher_disagreement_score":0.002988008,"about_ca_system_score_codex":0.0015366538,"about_ca_system_score_gemma":0.0010141588,"threshold_uncertainty_score":0.011149228},"labels":[],"label_agreement":null},{"id":"W2118356664","doi":"10.1074/jbc.m113.455832","title":"Calcineurin Regulates Nuclear Factor I Dephosphorylation and Activity in Malignant Glioma Cell Lines","year":2013,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Dephosphorylation; Calcineurin; Cancer research; Glioma; Cell culture; Chemistry; Cell biology; Biology; Phosphorylation; Internal medicine; Medicine; Genetics; Phosphatase; Transplantation","score_opus":0.01529048702647199,"score_gpt":0.23314775927640508,"score_spread":0.2178572722499331,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118356664","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9628334,0.008538299,0.014881965,0.00045337656,0.0002100824,0.00029983168,0.004642961,0.0006804418,0.0074596945],"genre_scores_gemma":[0.9557784,0.005215342,0.017694052,0.00018881739,0.00006932227,0.00059175,0.011564488,0.0001671147,0.008730864],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992126,0.00011483658,0.00010903015,0.00012666138,0.00032867314,0.00010820158],"domain_scores_gemma":[0.9997012,0.000053613523,0.000050620554,0.00006819515,0.000077248624,0.000049039736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004116783,0.0005284167,0.0004427812,0.0008238825,0.00050478755,0.00059191254,0.0005690595,0.00031750332,0.0017409414],"category_scores_gemma":[0.0002976876,0.00027790957,0.00042640473,0.0009866144,0.0003723002,0.00024473303,0.00037168665,0.00077024876,0.0008729937],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000099876095,0.00010406936,0.00034571023,0.00006189613,0.000010538806,0.00006160909,0.000068005545,0.000105907704,0.9975056,0.000148476,0.00022581968,0.0012625251],"study_design_scores_gemma":[0.00004172489,0.00030515416,0.0069141667,0.000013070676,0.000029079816,0.00040282772,0.00005675174,0.0019542219,0.98226523,0.00007480129,0.007929847,0.00001327932],"about_ca_topic_score_codex":0.005024669,"about_ca_topic_score_gemma":0.007834896,"teacher_disagreement_score":0.005024669,"about_ca_system_score_codex":0.00078282796,"about_ca_system_score_gemma":0.00039696135,"threshold_uncertainty_score":0.009990871},"labels":[],"label_agreement":null},{"id":"W2118521515","doi":"10.1152/ajpcell.00246.2008","title":"Tissue inhibitor of metalloproteinase-3 inhibits neonatal mouse cardiomyocyte proliferation via EGFR/JNK/SP-1 signaling","year":2009,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Tissue inhibitor of metalloproteinase; Cancer research; Metalloproteinase; Cell biology; Signal transduction; Chemistry; Matrix metalloproteinase; Medicine; Biology; Internal medicine","score_opus":0.005415092747238318,"score_gpt":0.22949768760001266,"score_spread":0.22408259485277435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118521515","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98690134,0.0057526226,0.0044927946,0.00019128605,0.00009382251,0.00004951795,0.00069283275,0.00015445852,0.0016712787],"genre_scores_gemma":[0.98577416,0.0051890663,0.004483473,0.000138513,0.000039104874,0.000115022565,0.001110379,0.000030047466,0.003120275],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987257,0.00002105619,0.000016953623,0.000015329417,0.000041811545,0.000032303327],"domain_scores_gemma":[0.99991286,0.000012455838,0.000031151318,0.000008072046,0.000011503146,0.000023926399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021251195,0.00044707803,0.0002907396,0.00023095154,0.00011835302,0.00018188142,0.00022285704,0.00015328109,0.0010286366],"category_scores_gemma":[0.00009767311,0.00010349495,0.0004039811,0.00011176578,0.00013688917,0.00014573356,0.00014834979,0.00073253445,0.00032768206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013261341,0.00005036347,0.00017477431,0.000057466827,0.0000066803686,0.00004661219,0.000008802013,0.00003142113,0.9979171,0.000027190257,0.000054652766,0.0014923079],"study_design_scores_gemma":[0.00003646999,0.0006841474,0.005759652,0.000009525761,0.000027411841,0.00024330044,0.000023219089,0.00065604784,0.99103516,0.000036202237,0.0014855535,0.0000032937357],"about_ca_topic_score_codex":0.000346197,"about_ca_topic_score_gemma":0.00088618015,"teacher_disagreement_score":0.0010286366,"about_ca_system_score_codex":0.00018416032,"about_ca_system_score_gemma":0.00023482372,"threshold_uncertainty_score":0.0034410954},"labels":[],"label_agreement":null},{"id":"W2118986663","doi":"10.1093/bioinformatics/btu581","title":"Human structural proteome-wide characterization of Cyclosporine A targets","year":2014,"lang":"en","type":"article","venue":"Bioinformatics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Computational biology; Proteome; Drug discovery; Cyclophilin; Surface plasmon resonance; Human proteome project; Biology; Docking (animal); Cyclophilin A; Biochemistry; Proteomics; Molecular biology; Medicine; Gene; Nanotechnology","score_opus":0.007432989959109125,"score_gpt":0.23173405607790284,"score_spread":0.22430106611879372,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2118986663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778942,0.00056295283,0.0045792973,0.00010173979,0.000006020055,0.000022419412,0.015346736,0.0006354969,0.000851085],"genre_scores_gemma":[0.91808724,0.00044349345,0.013938762,0.000048476268,0.000009323567,0.000034095443,0.06696003,0.00007784707,0.00040075183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998907,0.00001801844,0.0000072507223,0.00004670028,0.000026441958,0.000010811182],"domain_scores_gemma":[0.9998149,0.000051683695,0.00004183721,0.000022391496,0.000040656814,0.000028491944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021189424,0.00042381583,0.00028035848,0.00065959105,0.00025793142,0.00035008346,0.00022585609,0.00025626944,0.0010683215],"category_scores_gemma":[0.0004138604,0.00010714616,0.00036764878,0.0009396461,0.00013664972,0.00016912588,0.0002217261,0.00024621875,0.00045174191],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0031537386,0.0005475977,0.14755192,0.0010302303,0.0004739371,0.0014420293,0.00030969386,0.043896966,0.728089,0.0011311246,0.009605537,0.062768206],"study_design_scores_gemma":[0.0002128837,0.00091200176,0.4272904,0.00005656344,0.00038321203,0.0033183456,0.00036564743,0.26047432,0.2861057,0.001934049,0.018895801,0.00005113659],"about_ca_topic_score_codex":0.0021876676,"about_ca_topic_score_gemma":0.0025105595,"teacher_disagreement_score":0.0021876676,"about_ca_system_score_codex":0.0003441876,"about_ca_system_score_gemma":0.00039894888,"threshold_uncertainty_score":0.0043498874},"labels":[],"label_agreement":null},{"id":"W2120257962","doi":"10.1152/ajplung.00096.2005","title":"Constrictor-induced translocation of NFAT3 in human and rat pulmonary artery smooth muscle","year":2005,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research","keywords":"NFAT; Biology; Chromosomal translocation; Internal medicine; Vascular smooth muscle; Endocrinology; Calcineurin; Cell biology; Medicine; Biochemistry; Transplantation; Smooth muscle","score_opus":0.0054664841581703,"score_gpt":0.2311367420881933,"score_spread":0.225670257930023,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120257962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99069947,0.0055717006,0.0017062033,0.000130983,0.00003222845,0.000035801862,0.0004706252,0.00005089281,0.0013020119],"genre_scores_gemma":[0.99025047,0.0027118153,0.0022582593,0.000115797164,0.000034036868,0.00012319704,0.0016386968,0.000019360712,0.002848371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998235,0.0000342463,0.000012157895,0.000051708295,0.000036708134,0.00004171765],"domain_scores_gemma":[0.99992037,0.000017680233,0.000021991698,0.000013550811,0.000009106908,0.000017343857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024544506,0.00023595351,0.0001937478,0.00022887955,0.00016426672,0.0001904086,0.000105748244,0.0002539292,0.0019723591],"category_scores_gemma":[0.00020015158,0.00015982214,0.00040641613,0.00023428857,0.00029130172,0.00018401323,0.00015555519,0.00041665472,0.00044095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040225397,0.00002721907,0.0002453724,0.00004999168,0.0000065761756,0.00013169648,0.000057778503,0.000014084001,0.99815184,0.00004673177,0.000032981283,0.0008334558],"study_design_scores_gemma":[0.00012422519,0.0018631024,0.04986118,0.000020893463,0.00006439164,0.0028059569,0.00018654528,0.00069229613,0.93832904,0.00012695721,0.0059135347,0.000011770823],"about_ca_topic_score_codex":0.00096516625,"about_ca_topic_score_gemma":0.0011026531,"teacher_disagreement_score":0.0019723591,"about_ca_system_score_codex":0.0002773849,"about_ca_system_score_gemma":0.00017135721,"threshold_uncertainty_score":0.0065981746},"labels":[],"label_agreement":null},{"id":"W2120747625","doi":"10.1073/pnas.0932671100","title":"Expression of utrophin A mRNA correlates with the oxidative capacity of skeletal muscle fiber types and is regulated by calcineurin/NFAT signaling","year":2003,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":132,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"NFAT; Calcineurin; Utrophin; Skeletal muscle; Myosin; Cell biology; Molecular biology; Biology; Gene expression; Myocyte; Transcription factor; Chemistry; Dystrophin; Gene; Biochemistry; Endocrinology; Internal medicine; Transplantation","score_opus":0.018244301943896396,"score_gpt":0.25405247195102143,"score_spread":0.23580817000712503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2120747625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970016,0.00088532805,0.0014380341,0.000025573729,0.000005940071,0.000008804689,0.00019397156,0.000020849255,0.0004198936],"genre_scores_gemma":[0.99384815,0.0007528393,0.0026344208,0.000028711507,0.000009576606,0.00002911746,0.00050229515,0.000013316712,0.002181442],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99984014,0.00001263443,0.000015209077,0.000065052205,0.000041155974,0.000025751558],"domain_scores_gemma":[0.9997701,0.00003233592,0.00010091894,0.00001130751,0.0000258339,0.000059461425],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001469676,0.00027418294,0.0001564119,0.00048959197,0.00019953477,0.00021192919,0.00010567506,0.00020232533,0.0011917135],"category_scores_gemma":[0.00013922379,0.00015379055,0.00024285838,0.00019475685,0.0002713473,0.00021719106,0.00019604969,0.00029986954,0.00018301583],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000038147828,0.0000054161655,0.0011864805,0.000010586331,0.000003686209,0.0000180465,0.000009013053,0.000009008517,0.998343,0.00001175061,0.0000037179948,0.00036113453],"study_design_scores_gemma":[0.00001530706,0.0003255557,0.29195362,0.000015110009,0.000037422575,0.00061327434,0.000104240484,0.0011584562,0.7044983,0.0001173357,0.0011504862,0.000010861453],"about_ca_topic_score_codex":0.00096243346,"about_ca_topic_score_gemma":0.0014540213,"teacher_disagreement_score":0.0011917135,"about_ca_system_score_codex":0.00022311961,"about_ca_system_score_gemma":0.00010482339,"threshold_uncertainty_score":0.0039866567},"labels":[],"label_agreement":null},{"id":"W2121289770","doi":"10.1084/jem.20081140","title":"Rcan1 negatively regulates FcɛRI-mediated signaling and mast cell function","year":2009,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Killam Trusts; National Institutes of Health; Nova Scotia Health Research Foundation","keywords":"Degranulation; Mast cell; Cell biology; Histamine; Biology; Signal transduction; Calcineurin; Immunoglobulin E; Cytokine; Molecular biology; Regulator; Receptor; Immunology; Antibody; Transplantation; Internal medicine; Endocrinology; Biochemistry; Medicine","score_opus":0.011033502981840844,"score_gpt":0.2510946777229966,"score_spread":0.24006117474115576,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2121289770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916433,0.0037663358,0.001755354,0.00016794355,0.000018926128,0.000016929858,0.00017790147,0.000091324386,0.0023620238],"genre_scores_gemma":[0.9940631,0.0013011988,0.0011992924,0.00006144274,0.000010393114,0.000017674865,0.0003225971,0.0000226181,0.0030016825],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998292,0.00003329267,0.000009467413,0.00003847408,0.00005106315,0.000038567654],"domain_scores_gemma":[0.9998611,0.000027838896,0.00004882059,0.000017347758,0.000017832514,0.00002694854],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016737162,0.00052751385,0.00019928114,0.000253568,0.00020038741,0.0004506677,0.00045172469,0.00032284777,0.0010089716],"category_scores_gemma":[0.00020578693,0.00013907584,0.00015892129,0.00014056815,0.00033958576,0.00021062364,0.00023510377,0.00041388863,0.00042706783],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006471121,0.0000122135925,0.00020894935,0.0000203119,0.0000024390126,0.000068989,0.000008663807,0.00008077355,0.9981274,0.00014167534,0.00003497843,0.001228947],"study_design_scores_gemma":[0.000009565741,0.000057686328,0.0071341074,0.0000069256575,0.000013895353,0.00038618364,0.000018395118,0.0018007811,0.9876045,0.00010403433,0.0028578436,0.000006135822],"about_ca_topic_score_codex":0.00071198854,"about_ca_topic_score_gemma":0.00090683135,"teacher_disagreement_score":0.0010089716,"about_ca_system_score_codex":0.00071998226,"about_ca_system_score_gemma":0.00028946233,"threshold_uncertainty_score":0.0052238703},"labels":[],"label_agreement":null},{"id":"W2122083453","doi":"10.1182/blood.v97.8.2390","title":"Regulation of nuclear factor of activated T cells by phosphotyrosyl-specific phosphatase activity: a positive effect on HIV-1 long terminal repeat–driven transcription and a possible implication of SHP-1","year":2001,"lang":"en","type":"article","venue":"Blood","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier universitaire de Québec","funders":"Medical Research Council; Canadian Institutes of Health Research","keywords":"NFAT; Jurkat cells; Transcription factor; Phosphatase; Molecular biology; T cell; Biology; Cell biology; Long terminal repeat; Protein tyrosine phosphatase; HIV Long Terminal Repeat; Kinase; Phosphorylation; Biochemistry; Gene expression; Immunology; Immune system; Gene","score_opus":0.006633602514455158,"score_gpt":0.22047088272591503,"score_spread":0.21383728021145987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122083453","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99183685,0.0046075517,0.0021083031,0.00011598056,0.00005281216,0.000018874372,0.00014240164,0.00006346895,0.0010536702],"genre_scores_gemma":[0.99662554,0.0013731766,0.00070871203,0.000032053355,0.000021420505,0.00002057979,0.00017530195,0.000007625088,0.0010356125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984527,0.000039222476,0.000011930166,0.000028603452,0.000031035644,0.00004403123],"domain_scores_gemma":[0.99991906,0.00002213686,0.000019157162,0.00001078058,0.000008136701,0.000020748905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015731188,0.0005061127,0.00015483289,0.00014392131,0.00010938126,0.000304321,0.00019429057,0.00020549243,0.0012467562],"category_scores_gemma":[0.0001100839,0.000116191135,0.0002658716,0.0001033291,0.00023360513,0.00016447627,0.0001679425,0.00043646523,0.00019137509],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013937654,0.000022790555,0.00010774386,0.000039223458,0.0000040822965,0.000049768565,0.000013128443,0.000021657077,0.99843615,0.00008862776,0.000016061238,0.0010614718],"study_design_scores_gemma":[0.00002575244,0.0002833567,0.0025212315,0.000004481975,0.000015045121,0.00021786503,0.000015165435,0.0004467485,0.99524224,0.000045101566,0.0011807447,0.0000022308643],"about_ca_topic_score_codex":0.00022873358,"about_ca_topic_score_gemma":0.00031154024,"teacher_disagreement_score":0.0012467562,"about_ca_system_score_codex":0.00017952523,"about_ca_system_score_gemma":0.000116850024,"threshold_uncertainty_score":0.0041707754},"labels":[],"label_agreement":null},{"id":"W2122518329","doi":"10.1084/jem.20051150","title":"Autoamplification of NFATc1 expression determines its essential role in bone homeostasis","year":2005,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":848,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"NFAT; Biology; Cell biology; Osteoimmunology; Osteoclast; Ectopic expression; Embryonic stem cell; Epigenetics; Haematopoiesis; Cellular differentiation; Transcription factor; Stem cell; Genetics; Gene; In vitro; RANKL","score_opus":0.014138888342471975,"score_gpt":0.30254010039428314,"score_spread":0.2884012120518112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2122518329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939845,0.0012900208,0.0029749144,0.00007157059,0.00001722144,0.000006494461,0.00014539165,0.000059275342,0.0014507308],"genre_scores_gemma":[0.99594206,0.00058264914,0.0016002076,0.000017973662,0.000008811686,0.000007432968,0.00022483077,0.000016914057,0.001599087],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986255,0.000013857238,0.000011505036,0.000035624205,0.000035900935,0.000040474217],"domain_scores_gemma":[0.99979633,0.000047788006,0.000051829677,0.00003331988,0.000026782316,0.000043940316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013602206,0.000223315,0.00013351496,0.0002010473,0.00016190294,0.00027814365,0.00018863658,0.00021716,0.001757382],"category_scores_gemma":[0.00019974113,0.00015096678,0.00013123486,0.00013069513,0.00037480186,0.00020916549,0.00016289011,0.0004459809,0.00046318516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000031416577,0.00000558775,0.0003710334,0.000007502286,7.204011e-7,0.000026356644,0.0000056814633,0.000010301792,0.9988084,0.0001069634,0.000005564623,0.0006203894],"study_design_scores_gemma":[0.00001022347,0.00007161545,0.010635626,0.000004677424,0.000010192182,0.0007430364,0.000027894199,0.0003379065,0.9858111,0.00021508243,0.0021296432,0.0000029763344],"about_ca_topic_score_codex":0.0004885156,"about_ca_topic_score_gemma":0.0009230791,"teacher_disagreement_score":0.001757382,"about_ca_system_score_codex":0.000303041,"about_ca_system_score_gemma":0.00024231599,"threshold_uncertainty_score":0.0058790445},"labels":[],"label_agreement":null},{"id":"W2124169942","doi":"10.1096/fj.13-231688","title":"miR‐17 targets tissue inhibitor of metalloproteinase 1 and 2 to modulate cardiac matrix remodeling","year":2013,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Sunnybrook Health Science Centre; University of Toronto; Health Sciences Centre; University Health Network","funders":"Canadian Institutes of Health Research","keywords":"TIMP1; Myocardial infarction; Ventricular remodeling; Cardiac function curve; microRNA; Endogeny; Heart failure; Untranslated region; Chemistry; Matrix metalloproteinase; MMP9; Antagomir; Internal medicine; Medicine; Endocrinology; Messenger RNA; Downregulation and upregulation; Gene expression; Biochemistry; Gene","score_opus":0.009796311148137097,"score_gpt":0.24923362435368165,"score_spread":0.23943731320554457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2124169942","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9766703,0.009837958,0.008725745,0.00042603255,0.00026214783,0.000121124685,0.00081723783,0.00019437024,0.0029449447],"genre_scores_gemma":[0.9743561,0.0074014543,0.010998862,0.00027028559,0.00007484359,0.00016556025,0.0010130631,0.000061054394,0.0056587923],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998242,0.000030849995,0.000016113507,0.000029878323,0.000046090587,0.000052860913],"domain_scores_gemma":[0.99985325,0.000021011332,0.000060788043,0.000012352655,0.000019397794,0.000033193894],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035426594,0.00046845397,0.00040467683,0.00034401653,0.00018124675,0.0006040314,0.0002139106,0.00026065894,0.001899729],"category_scores_gemma":[0.00017433144,0.00026705343,0.0005071237,0.00018740978,0.00026465763,0.00025060718,0.00023046586,0.0008524384,0.0006744157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034216908,0.00010307137,0.001784146,0.0001578732,0.000032132302,0.00016845197,0.00003937758,0.00018366626,0.99166846,0.00027459156,0.00017810409,0.0050679487],"study_design_scores_gemma":[0.000069003734,0.0010254513,0.009233351,0.000026275196,0.000080127,0.0007678262,0.000076414704,0.0016434981,0.97583824,0.0001353057,0.011093401,0.000011152175],"about_ca_topic_score_codex":0.00026503438,"about_ca_topic_score_gemma":0.0006531862,"teacher_disagreement_score":0.001899729,"about_ca_system_score_codex":0.00027869872,"about_ca_system_score_gemma":0.0004206101,"threshold_uncertainty_score":0.0063551664},"labels":[],"label_agreement":null},{"id":"W2125833512","doi":"10.1051/medsci/200319121251","title":"Pin1 : une peptidyl-prolyl cis/trans isomérase aux rôles insoupçonnés","year":2003,"lang":"fr","type":"review","venue":"médecine/sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Molecular biology; Chemistry; PIN1; Peptidylprolyl isomerase; Isomerase; Biology; Biochemistry; Enzyme","score_opus":0.07298227963396568,"score_gpt":0.34859132005640714,"score_spread":0.27560904042244144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2125833512","genre_codex":"empirical","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6360619,0.045724105,0.18897243,0.0032149446,0.0033948151,0.0015734492,0.03862648,0.026830206,0.055601727],"genre_scores_gemma":[0.75109667,0.012589919,0.060868725,0.0012825482,0.00030321078,0.0010559697,0.033064745,0.0037234703,0.13601488],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99953294,0.000037431255,0.000031344163,0.00015612756,0.00016088998,0.000081350285],"domain_scores_gemma":[0.9997538,0.000030754032,0.000077480596,0.000027001339,0.000022938413,0.0000881493],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002486529,0.0017968289,0.0006276305,0.00085498736,0.0008251467,0.001196864,0.0012331788,0.0008625658,0.008517519],"category_scores_gemma":[0.00025123922,0.00054893945,0.00056945503,0.0006030316,0.00064566615,0.0006916631,0.0014576016,0.002311713,0.007520245],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043572858,0.000048475365,0.00023230704,0.00017102215,0.000012280453,0.00037815224,0.000026853715,0.0002883329,0.9783856,0.00153138,0.0020076113,0.016482214],"study_design_scores_gemma":[0.00013413494,0.00044113773,0.0033444585,0.000050074552,0.00006730278,0.0025297306,0.000038492148,0.002444219,0.7904927,0.00047153042,0.19992512,0.00006120687],"about_ca_topic_score_codex":0.00068396115,"about_ca_topic_score_gemma":0.00068997836,"teacher_disagreement_score":0.008517519,"about_ca_system_score_codex":0.0009591924,"about_ca_system_score_gemma":0.0004973699,"threshold_uncertainty_score":0.028494},"labels":[],"label_agreement":null},{"id":"W2126058718","doi":"10.1091/mbc.11.11.3925","title":"Developmental Regulation of FKBP65","year":2000,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; University of Toronto","keywords":"Tropoelastin; Biology; Endoplasmic reticulum; Extracellular matrix; Cell biology; Extracellular; Subcellular localization; Elastin; Golgi apparatus; Molecular biology; Cytoplasm; Genetics","score_opus":0.005191380305098518,"score_gpt":0.21717551523307976,"score_spread":0.21198413492798124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126058718","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9693253,0.01188277,0.009755558,0.0002856977,0.00016571696,0.000036536774,0.00212503,0.00032374624,0.0060997074],"genre_scores_gemma":[0.9860308,0.0022921131,0.001784002,0.00016589586,0.000018722683,0.00004445066,0.0013871122,0.000086243104,0.008190665],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975675,0.00001958813,0.000026811435,0.00008247634,0.000047144695,0.00006720913],"domain_scores_gemma":[0.9996245,0.00004267232,0.00011243774,0.000023188524,0.00007721743,0.00011995675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012850497,0.0003159766,0.00022767787,0.00050602324,0.0003693401,0.0005805643,0.0002600835,0.00043449568,0.0017958559],"category_scores_gemma":[0.00025576368,0.00024564195,0.00034048906,0.00019322387,0.0003264467,0.00028810417,0.0006461081,0.0006490351,0.0009341625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010495434,0.000010393344,0.0013519386,0.000044813707,0.0000066200405,0.00024448294,0.00007878008,0.000036771286,0.99502313,0.00041368135,0.00016820223,0.0025162245],"study_design_scores_gemma":[0.00002283077,0.00013667236,0.19472206,0.00009018953,0.000071057075,0.0012467664,0.00028929967,0.0011529439,0.77288574,0.00031018624,0.02903669,0.000035505112],"about_ca_topic_score_codex":0.0029088238,"about_ca_topic_score_gemma":0.002643386,"teacher_disagreement_score":0.0029088238,"about_ca_system_score_codex":0.00069864176,"about_ca_system_score_gemma":0.00029435568,"threshold_uncertainty_score":0.006007731},"labels":[],"label_agreement":null},{"id":"W2126161263","doi":"10.1016/j.ajpath.2011.05.022","title":"Regulator of Calcineurin 1 (Rcan1) Is Required for the Development of Pulmonary Eosinophilia in Allergic Inflammation in Mice","year":2011,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Killam Trusts","keywords":"Regulator; Calcineurin; Eosinophilia; Allergic inflammation; Inflammation; Immunology; Pulmonary Eosinophilia; Medicine; Internal medicine; Biology; Eosinophil; Asthma; Transplantation","score_opus":0.02448828308825028,"score_gpt":0.2649072731700617,"score_spread":0.2404189900818114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126161263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855467,0.0030657873,0.00546659,0.0008452306,0.00018047006,0.000056316927,0.0013652022,0.00049430766,0.00297937],"genre_scores_gemma":[0.9874326,0.00085232593,0.003313633,0.00023695132,0.00004120842,0.00008025387,0.00088867225,0.00017815479,0.0069762995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991665,0.00012136421,0.00006401009,0.00018333437,0.0003088793,0.00015604323],"domain_scores_gemma":[0.9989974,0.000107898326,0.00041751628,0.00010680738,0.00006094297,0.00030938297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041453858,0.0008619973,0.00044877396,0.0013626497,0.0005269744,0.0009221138,0.00087944866,0.0012410011,0.00291842],"category_scores_gemma":[0.00035071798,0.00057828875,0.0005435847,0.0003139569,0.0008946574,0.00048754193,0.0004344365,0.00269617,0.00090549915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018480398,0.000044896406,0.00019833967,0.000028322018,0.000007896591,0.00020034453,0.000012015204,0.00011643864,0.99821967,0.0003211294,0.00009608768,0.0005700849],"study_design_scores_gemma":[0.00008057402,0.0001427828,0.00668769,0.000020531634,0.000054536526,0.0011126242,0.000054546406,0.0025981525,0.9853805,0.0002194314,0.0036356717,0.000012970497],"about_ca_topic_score_codex":0.00092212047,"about_ca_topic_score_gemma":0.0020808151,"teacher_disagreement_score":0.00291842,"about_ca_system_score_codex":0.0009248586,"about_ca_system_score_gemma":0.0006259639,"threshold_uncertainty_score":0.009763122},"labels":[],"label_agreement":null},{"id":"W2126248599","doi":"10.1534/genetics.110.124222","title":"A Link Between Impaired Purine Nucleotide Synthesis and Apoptosis in <i>Drosophila melanogaster</i>","year":2011,"lang":"en","type":"article","venue":"Genetics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"New Brunswick Innovation Foundation; Canadian Institutes of Health Research; Canada's Michael Smith Genome Sciences Centre; Fondation de la recherche en santé du Nouveau-Brunswick","keywords":"Biology; Imaginal disc; Drosophila melanogaster; Molecular biology; Mutant; Cell biology; Genetics; Gene","score_opus":0.02573999510118037,"score_gpt":0.2318813806647561,"score_spread":0.20614138556357575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126248599","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942115,0.0015743532,0.0017751281,0.00010328937,0.000016491897,0.000026121572,0.0011622622,0.00010220896,0.0010286805],"genre_scores_gemma":[0.9923827,0.00093651033,0.0021611622,0.00013635009,0.000012210081,0.00004813102,0.0014306364,0.000031731128,0.0028606371],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999138,0.000008446476,0.000011371527,0.00003254564,0.000020314865,0.000013550232],"domain_scores_gemma":[0.9998423,0.00002788285,0.00006746637,0.000013319307,0.00001574076,0.00003330584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006198101,0.00047745343,0.00022361244,0.00030338415,0.00017258571,0.00030185672,0.00018674301,0.0003098953,0.0009716575],"category_scores_gemma":[0.00008942298,0.0001878739,0.00023317698,0.000118720716,0.00021440536,0.0001563117,0.00018049707,0.00046379416,0.00022260453],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000044294597,0.0000070530373,0.0006670363,0.000035244513,0.0000057016828,0.00011266956,0.000007780184,0.000027423099,0.9987085,0.000029469018,0.000022846894,0.00033199502],"study_design_scores_gemma":[0.000021170465,0.00021978632,0.072262906,0.0000117569625,0.00004264964,0.0011726504,0.00005021049,0.00095609145,0.9233328,0.00007768347,0.0018426024,0.0000097849],"about_ca_topic_score_codex":0.0009482499,"about_ca_topic_score_gemma":0.002018619,"teacher_disagreement_score":0.0009716575,"about_ca_system_score_codex":0.0004224183,"about_ca_system_score_gemma":0.00010149793,"threshold_uncertainty_score":0.0032504797},"labels":[],"label_agreement":null},{"id":"W2126301105","doi":"10.1038/emboj.2009.120","title":"Structural basis for ADP‐mediated transcriptional regulation by P1 and P7 ParA","year":2009,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":79,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; National Institutes of Health","keywords":"Biology; Regulation of gene expression; Cell biology; Computational biology; Genetics; Gene","score_opus":0.016843638190877572,"score_gpt":0.25911330792753545,"score_spread":0.24226966973665787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126301105","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9407757,0.0027207097,0.03860787,0.0017470194,0.00060635665,0.00009545576,0.00081250916,0.0005830413,0.014051403],"genre_scores_gemma":[0.9929524,0.0004294013,0.0030715917,0.00017282301,0.000058654,0.00004383482,0.0005674233,0.000030212714,0.0026735603],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999057,0.000018828348,0.0000064581377,0.000028255023,0.000017997552,0.000022710328],"domain_scores_gemma":[0.99980813,0.00006479571,0.000027609332,0.00003187871,0.00002276631,0.000044801935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018541023,0.00036360585,0.00031412576,0.00012705733,0.00061135663,0.0005527863,0.0005971868,0.0007061058,0.0043560513],"category_scores_gemma":[0.00033568247,0.00018939406,0.00035303147,0.00012938447,0.00053484656,0.00037566808,0.00038406265,0.0009849746,0.002219338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009922486,0.000097812794,0.0005121838,0.00013451955,0.000012790041,0.0008581093,0.0001233837,0.0014558805,0.961965,0.026765076,0.0010000491,0.006082879],"study_design_scores_gemma":[0.00010931909,0.0004093178,0.002638037,0.000018660121,0.000014298712,0.00086214807,0.00016464775,0.008924674,0.960786,0.007918116,0.018119952,0.00003494711],"about_ca_topic_score_codex":0.00038545846,"about_ca_topic_score_gemma":0.00040732222,"teacher_disagreement_score":0.0043560513,"about_ca_system_score_codex":0.00042682645,"about_ca_system_score_gemma":0.00029710037,"threshold_uncertainty_score":0.014572442},"labels":[],"label_agreement":null},{"id":"W2126629462","doi":"10.1677/jme.1.02052","title":"Cyclosporin A inhibits apolipoprotein AI gene expression","year":2006,"lang":"en","type":"article","venue":"Journal of Molecular Endocrinology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Calcineurin; Apolipoprotein B; Gene expression; Transfection; Calcium in biology; Chemistry; Reporter gene; Hyperlipidemia; Molecular biology; Intracellular; Endocrinology; Biology; Gene; Internal medicine; Cholesterol; Biochemistry; Medicine; Transplantation","score_opus":0.0056540824573508616,"score_gpt":0.23944378499362035,"score_spread":0.2337897025362695,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126629462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907829,0.002454903,0.0018966012,0.00025318892,0.00010748119,0.00003976239,0.00027696023,0.0002225669,0.0039655278],"genre_scores_gemma":[0.99207366,0.0021384435,0.0012088811,0.000081298975,0.000043099935,0.00004485121,0.0003999429,0.00002281784,0.003986902],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987876,0.0000240192,0.0000116048295,0.000019678977,0.000035509456,0.000030384002],"domain_scores_gemma":[0.99980813,0.000053507796,0.000039713177,0.000025018117,0.000022685426,0.000051011553],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010849838,0.00023975175,0.00019830273,0.00028463107,0.00015800941,0.00027907893,0.00015246085,0.00019104472,0.0010448935],"category_scores_gemma":[0.00016498724,0.00006467122,0.00016243472,0.00019128315,0.00024380215,0.00008032097,0.00010835415,0.0005503603,0.00030213917],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014212473,0.00007245521,0.00023065099,0.000033250013,0.0000060110083,0.00003678623,0.000008701381,0.000052758307,0.99607134,0.00015954618,0.000119117736,0.003067236],"study_design_scores_gemma":[0.000057659512,0.0005966101,0.0048429295,0.0000069131024,0.000014176584,0.00017313806,0.000016458194,0.000997102,0.98831344,0.000058458427,0.0049197995,0.0000034054283],"about_ca_topic_score_codex":0.000760234,"about_ca_topic_score_gemma":0.0012682291,"teacher_disagreement_score":0.0010448935,"about_ca_system_score_codex":0.00033146786,"about_ca_system_score_gemma":0.0003916602,"threshold_uncertainty_score":0.0034955144},"labels":[],"label_agreement":null},{"id":"W2126920351","doi":"10.1021/np0702887","title":"Protein Phosphatase Inhibitors Isolated from <i>Spongia irregularis</i> Collected in Papua New Guinea","year":2007,"lang":"en","type":"article","venue":"Journal of Natural Products","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; University of Alberta; University of British Columbia","funders":"Universiteit van Amsterdam","keywords":"Phosphatase; New guinea; Stereochemistry; Sponge; Biochemistry; Protein phosphatase 2; Calcineurin; Chemistry; Biology; Guinea pig; Enzyme; Botany","score_opus":0.006831390875574267,"score_gpt":0.23089207495799602,"score_spread":0.22406068408242175,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2126920351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891192,0.004339485,0.0014918048,0.00013342025,0.000034966775,0.0001151813,0.00059435837,0.000049006565,0.004122446],"genre_scores_gemma":[0.987633,0.0047721607,0.0022924235,0.00015134238,0.000020911826,0.00006255288,0.0011080357,0.000015527447,0.0039439606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999684,0.0000028578331,0.0000022900613,0.0000085676675,0.0000098096225,0.000008176168],"domain_scores_gemma":[0.99994445,0.000008008259,0.000013217914,0.0000031862312,0.000012773629,0.000018314506],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008173533,0.00039799506,0.00023537356,0.00059687527,0.0002209027,0.00019840163,0.00013387177,0.00012877004,0.0010042718],"category_scores_gemma":[0.00012144897,0.000119696575,0.00017189463,0.00023438824,0.00022156021,0.00013416582,0.00019724481,0.0003312897,0.00016303071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020209582,0.000039563063,0.0030676462,0.00019279521,0.000036433892,0.0002986999,0.00006607834,0.0001833928,0.9815,0.00008741345,0.00010096088,0.014224942],"study_design_scores_gemma":[0.00013457311,0.0019903523,0.12391772,0.00011173764,0.0002345878,0.0025434764,0.0003791967,0.0009561347,0.84568244,0.00026702308,0.023752516,0.000030213401],"about_ca_topic_score_codex":0.003250295,"about_ca_topic_score_gemma":0.007963618,"teacher_disagreement_score":0.003250295,"about_ca_system_score_codex":0.00019316546,"about_ca_system_score_gemma":0.0003644497,"threshold_uncertainty_score":0.006462753},"labels":[],"label_agreement":null},{"id":"W2127378602","doi":"10.1128/ec.3.1.61-71.2004","title":"The Ca <sup>2+</sup> /Calcineurin-Regulated <i>cup</i> Gene Family in <i>Dictyostelium discoideum</i> and Its Possible Involvement in Development","year":2004,"lang":"en","type":"article","venue":"Eukaryotic Cell","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"China University of Petroleum, Beijing","keywords":"Dictyostelium discoideum; Biology; Calcineurin; Cell biology; Dictyostelium; Gene; Gene family; Genetics; Gene expression","score_opus":0.010339847144894046,"score_gpt":0.21501238784556728,"score_spread":0.20467254070067323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2127378602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98923653,0.0027584983,0.004850396,0.00020246733,0.000033752407,0.000042063275,0.0015016142,0.0001216301,0.0012531253],"genre_scores_gemma":[0.98255724,0.00093946175,0.006272119,0.00027357697,0.000026240266,0.00008614262,0.0057041803,0.000051418592,0.004089543],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991953,0.0000066895163,0.000008866345,0.000029088962,0.000017601516,0.00001819072],"domain_scores_gemma":[0.9998461,0.000026421469,0.00004831809,0.000018934361,0.000027124524,0.000033098382],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000092655595,0.00038999537,0.00022746371,0.00028688306,0.00021702876,0.0002411967,0.00017547583,0.00020695497,0.00045439473],"category_scores_gemma":[0.00012950803,0.00014282217,0.00036200738,0.00020357542,0.0002488588,0.00015704524,0.00020993412,0.0004035446,0.00036027047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039201095,0.0000026061225,0.0002806661,0.000026650805,0.0000012442941,0.00004633374,0.000012345363,0.000013806492,0.99885714,0.00003440087,0.000027872677,0.0006577735],"study_design_scores_gemma":[0.00001568508,0.000114583076,0.039966896,0.000016473807,0.000039487564,0.001143057,0.00006075765,0.0010260822,0.952232,0.00008938278,0.00528521,0.000010374751],"about_ca_topic_score_codex":0.0010060387,"about_ca_topic_score_gemma":0.0010259305,"teacher_disagreement_score":0.0010060387,"about_ca_system_score_codex":0.00038722262,"about_ca_system_score_gemma":0.00028964758,"threshold_uncertainty_score":0.0028095245},"labels":[],"label_agreement":null},{"id":"W2129513783","doi":"10.1111/j.1365-2559.2006.02516.x","title":"Increasing EMMPRIN and matriptase expression in hepatocellular carcinoma: tissue microarray analysis of immunohistochemical scores with clinicopathological parameters","year":2006,"lang":"en","type":"article","venue":"Histopathology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Defence Medical Centre","funders":"","keywords":"Immunostaining; Tissue microarray; Immunohistochemistry; Pathology; Basigin; Medicine; Hepatocellular carcinoma; Stage (stratigraphy); Grading (engineering); Carcinoma; Internal medicine; Matrix metalloproteinase; Biology","score_opus":0.010313422932606233,"score_gpt":0.24222261402737127,"score_spread":0.23190919109476504,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129513783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979303,0.0003116467,0.0010141707,0.000027146283,0.000004322311,0.000008304811,0.00033431174,0.00001426672,0.00035562515],"genre_scores_gemma":[0.998099,0.00012854548,0.000944033,0.000012408959,0.0000073304877,0.000029046443,0.00041543887,0.000002881695,0.00036120467],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99971586,0.00006792872,0.000031866344,0.00007781502,0.00006922854,0.00003732431],"domain_scores_gemma":[0.99968493,0.000083714505,0.00010585594,0.000036266032,0.00005409259,0.0000351357],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035616348,0.00015014446,0.00026144195,0.00065663876,0.00016062865,0.00028805804,0.00012715612,0.00020120722,0.0010899294],"category_scores_gemma":[0.0005419248,0.00013443515,0.00014382914,0.00069418276,0.00010112126,0.00021790813,0.00014618505,0.00019084373,0.0002540418],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010634301,0.000079168014,0.7207122,0.00009324723,0.00017223156,0.00025259148,0.00014696806,0.00046587927,0.2577547,0.00006290858,0.00037145437,0.018825298],"study_design_scores_gemma":[0.0000059673853,0.00010876593,0.98592454,0.000004042247,0.000052787622,0.0006254408,0.00009426328,0.001582443,0.011066277,0.000038052985,0.00049028645,0.0000070266597],"about_ca_topic_score_codex":0.00045562023,"about_ca_topic_score_gemma":0.00071037584,"teacher_disagreement_score":0.0010899294,"about_ca_system_score_codex":0.00015459597,"about_ca_system_score_gemma":0.00011842989,"threshold_uncertainty_score":0.003646195},"labels":[],"label_agreement":null},{"id":"W2129621365","doi":"10.1186/s12870-014-0282-7","title":"Genome-wide analysis of Cyclophilin gene family in soybean (Glycine max)","year":2014,"lang":"en","type":"article","venue":"BMC Plant Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada; Western University","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; Genome; Gene; Gene family; Genetics; Gene duplication; Cyclophilin; Tandem exon duplication; Intron; Functional divergence","score_opus":0.015382883858602748,"score_gpt":0.2401843261340424,"score_spread":0.22480144227543963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2129621365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9916466,0.0011580102,0.00035980344,0.000038497656,0.0000050077915,0.000008088639,0.0062969825,0.000021298454,0.00046570305],"genre_scores_gemma":[0.98395306,0.0005750449,0.0010960061,0.000055673136,0.00000755906,0.000024007986,0.0137929795,0.000010569384,0.0004851229],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991906,0.0000051855345,0.0000045927923,0.000044134496,0.000017648521,0.000009270347],"domain_scores_gemma":[0.9998903,0.000020188427,0.000042082673,0.0000047315657,0.000016219474,0.000026398306],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012257157,0.00016258952,0.0001956536,0.0006850143,0.00015765755,0.00015696813,0.00007880503,0.0001462768,0.0008996688],"category_scores_gemma":[0.000118681884,0.00005850054,0.00022339528,0.00072561746,0.000078045436,0.000059591002,0.00012813031,0.00015038332,0.00016046196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008765595,0.000045447196,0.41440973,0.00045417924,0.00025695865,0.00064441847,0.00023163119,0.00037605685,0.5650507,0.00011216441,0.0009779717,0.016564101],"study_design_scores_gemma":[0.000007815223,0.000043170403,0.9953803,0.000007181706,0.000056227338,0.0003847562,0.000043733093,0.00019888654,0.0026807825,0.000023503195,0.0011711718,0.0000024689634],"about_ca_topic_score_codex":0.0015126085,"about_ca_topic_score_gemma":0.0029193887,"teacher_disagreement_score":0.0015126085,"about_ca_system_score_codex":0.00013597615,"about_ca_system_score_gemma":0.00010707752,"threshold_uncertainty_score":0.003009677},"labels":[],"label_agreement":null},{"id":"W2130099785","doi":"10.1016/s0960-894x(02)00612-1","title":"Targeting thrombin and factor VIIa: design, synthesis, and inhibitory activity of functionally relevant indolizidinones","year":2002,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":52,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; AstraZeneca","keywords":"Chemistry; Thrombin; Factor VIIa; Serine protease; Docking (animal); Molecular model; Active site; Stereochemistry; Discovery and development of direct thrombin inhibitors; Serine; Protease; Combinatorial chemistry; Biochemistry; Pharmacology; Enzyme; Tissue factor; Coagulation; Platelet; Immunology","score_opus":0.019374099015869898,"score_gpt":0.21033608878333143,"score_spread":0.19096198976746154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2130099785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9561875,0.0158739,0.01852881,0.0006646059,0.000113808725,0.00018474055,0.0004019507,0.00018764369,0.007857127],"genre_scores_gemma":[0.9793392,0.0084424345,0.0075700083,0.00014807984,0.000031772353,0.00006608155,0.00034975883,0.000029154478,0.004023692],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999392,0.000014128677,0.0000054055413,0.0000107204105,0.000012247927,0.00001834019],"domain_scores_gemma":[0.99994636,0.000006992699,0.000017649087,0.0000046703476,0.000008083655,0.000016271822],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017862147,0.00041224502,0.00022108456,0.00020010312,0.00014987813,0.00028665914,0.00045963592,0.00022630357,0.0008653063],"category_scores_gemma":[0.000137316,0.00015093453,0.00016980585,0.00012579562,0.00020549694,0.00024295934,0.00016703538,0.00053285796,0.00043949945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038226723,0.00011558353,0.0001303254,0.00016101496,0.00001061128,0.00024054186,0.00006413173,0.0014377402,0.9823276,0.0018181769,0.00023611463,0.013075852],"study_design_scores_gemma":[0.00015846764,0.0012010226,0.00048226558,0.000015628833,0.000029493029,0.0004959016,0.000030175857,0.0012724147,0.9824723,0.0003988381,0.013427585,0.000015863026],"about_ca_topic_score_codex":0.00029884977,"about_ca_topic_score_gemma":0.00058280805,"teacher_disagreement_score":0.0008653063,"about_ca_system_score_codex":0.00037183907,"about_ca_system_score_gemma":0.00022660865,"threshold_uncertainty_score":0.0028947592},"labels":[],"label_agreement":null},{"id":"W2131887841","doi":"10.1038/npg.els.0004033","title":"Lymphocytes: Antigen‐induced Gene Activation","year":2005,"lang":"en","type":"other","venue":"Encyclopedia of Life Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials","funders":"","keywords":"clone (Java method); Antigen; Gene; Biology; Immune system; Phenotype; Cell biology; Receptor; Lymphocyte; Immunology; Gene expression; Molecular biology; Genetics","score_opus":0.017656289529724666,"score_gpt":0.2733774918045206,"score_spread":0.25572120227479594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2131887841","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13306937,0.35077143,0.039420288,0.0042074076,0.004737613,0.00035242928,0.0072954465,0.0022259455,0.4579201],"genre_scores_gemma":[0.46506727,0.15606363,0.00929034,0.002073451,0.0011610482,0.0003202913,0.0045806337,0.00027704338,0.36116627],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998136,0.0000278182,0.000006982262,0.00005157319,0.000059828057,0.00004011181],"domain_scores_gemma":[0.99992204,0.000016599774,0.000014945091,0.000008827338,0.000015621805,0.000021999118],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017435371,0.0005657832,0.00035426117,0.00076035137,0.0003155479,0.0016110683,0.0003958047,0.00056467555,0.028359527],"category_scores_gemma":[0.00017596321,0.0001347154,0.0002957997,0.0010104708,0.0003010443,0.00045168312,0.00062299427,0.000723768,0.011750928],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008326665,0.0003947821,0.0010400628,0.0031003773,0.000053217038,0.002267644,0.00027919363,0.0007953328,0.5702592,0.049048312,0.042626366,0.3293028],"study_design_scores_gemma":[0.00010633091,0.0003640919,0.00475745,0.00050118245,0.000084153355,0.003117812,0.00025581822,0.00070430443,0.25434488,0.017007418,0.7187195,0.00003708163],"about_ca_topic_score_codex":0.0002963931,"about_ca_topic_score_gemma":0.00032963944,"teacher_disagreement_score":0.028359527,"about_ca_system_score_codex":0.00047242214,"about_ca_system_score_gemma":0.00029265016,"threshold_uncertainty_score":0.09487206},"labels":[],"label_agreement":null},{"id":"W2132437442","doi":"10.1186/1477-5956-7-2","title":"Glycoproteomic analysis of two mouse mammary cell lines during transforming growth factor (TGF)-beta induced epithelial to mesenchymal transition","year":2009,"lang":"en","type":"article","venue":"Proteome Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Biotechnology Research Institute; National Research Council Canada; Institute for Biological Sciences","funders":"National Research Council Canada","keywords":"Epithelial–mesenchymal transition; Basigin; Transforming growth factor beta; Cell adhesion; Biology; Cell biology; Fibronectin; Carcinogenesis; Cell migration; Transforming growth factor; Cell signaling; Cell culture; Cell adhesion molecule; Integrin; Cell; Signal transduction; Extracellular matrix; Metastasis; Cancer; Biochemistry; Genetics","score_opus":0.011647087732167308,"score_gpt":0.2619143427474312,"score_spread":0.25026725501526387,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2132437442","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99189514,0.0015811234,0.0032070486,0.00010433684,0.000027905839,0.00006857825,0.001950766,0.00005446042,0.0011106626],"genre_scores_gemma":[0.9743095,0.0025538593,0.012581078,0.00030274267,0.000019453208,0.000218467,0.0070839534,0.0000534343,0.0028775902],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999058,0.0000101365795,0.0000058452574,0.000018273166,0.000038041748,0.000021855769],"domain_scores_gemma":[0.99987495,0.00002043392,0.000028806113,0.000008176347,0.000037887283,0.000029649347],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015058019,0.00044573206,0.00031195575,0.000512526,0.00017237569,0.0002932425,0.00018227204,0.00031699066,0.00040783972],"category_scores_gemma":[0.00014160134,0.00011876011,0.00032970135,0.000368187,0.00015123506,0.00016136921,0.00022862392,0.00049559237,0.00020804847],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007447561,0.000009770006,0.0003584102,0.000018442077,0.0000057002067,0.00004211505,0.000012263849,0.000010523132,0.9990767,0.000011713569,0.000011263593,0.0003685411],"study_design_scores_gemma":[0.000030073477,0.00047117413,0.13721043,0.000020379182,0.000116795956,0.001120026,0.00021942978,0.0016862099,0.85573393,0.00007199722,0.0033009462,0.000018657096],"about_ca_topic_score_codex":0.00071260455,"about_ca_topic_score_gemma":0.0012115643,"teacher_disagreement_score":0.00071260455,"about_ca_system_score_codex":0.00019557118,"about_ca_system_score_gemma":0.00016540165,"threshold_uncertainty_score":0.0014190078},"labels":[],"label_agreement":null},{"id":"W2135247993","doi":"10.1002/jcb.10026","title":"Calcium‐ and FK506‐independent interaction between the immunophilin FKBP51 and calcineurin*","year":2002,"lang":"en","type":"article","venue":"Journal of Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council Canada; American Cancer Society","keywords":"Calcineurin; FKBP; NFAT; Calmodulin; Calmodulin-binding proteins; Biochemistry; Chemistry; Molecular biology; Phosphatase; Transcription factor; Biology; Phosphorylation; Enzyme; Transplantation","score_opus":0.019099564752929718,"score_gpt":0.2506273889542654,"score_spread":0.23152782420133566,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135247993","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99279356,0.0016410057,0.0035571326,0.00014149408,0.000046728423,0.00002858454,0.00024586264,0.00004649775,0.0014990848],"genre_scores_gemma":[0.9931438,0.00041187316,0.0025549105,0.00006574628,0.000012274094,0.00003359481,0.00065693667,0.000014570898,0.0031062122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980706,0.000033473494,0.000018257879,0.000047976337,0.000044196735,0.000049016966],"domain_scores_gemma":[0.99987495,0.000034581084,0.000035564866,0.000017866432,0.000011941391,0.000025126097],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010882061,0.00049749296,0.00024422488,0.00014464554,0.00029263145,0.00022232709,0.00030468038,0.00033949982,0.0014784955],"category_scores_gemma":[0.0001237679,0.00017960383,0.00033153204,0.00014739016,0.00022753834,0.0001657016,0.0002593659,0.00048105873,0.0005800328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052221123,0.000014787351,0.0001780562,0.000016435773,0.0000055333912,0.00006290761,0.0000062759395,0.000031356452,0.999186,0.000075002456,0.000025954983,0.0003456413],"study_design_scores_gemma":[0.000010331526,0.00007207221,0.0060396483,0.0000051038637,0.00002139962,0.00036612217,0.000013378342,0.0009863457,0.98947185,0.000028286751,0.00298059,0.000004876131],"about_ca_topic_score_codex":0.001258821,"about_ca_topic_score_gemma":0.0023888801,"teacher_disagreement_score":0.0014784955,"about_ca_system_score_codex":0.0006505635,"about_ca_system_score_gemma":0.00014537659,"threshold_uncertainty_score":0.004946053},"labels":[],"label_agreement":null},{"id":"W2135820246","doi":"10.4141/a01-023","title":"Calcineurin-mediated signaling in skeletal muscle","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Animal Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"NFAT; Calcineurin; Muscle hypertrophy; Signal transduction; Cell biology; Skeletal muscle; Transcription factor; Biology; Phosphatase; Calcium signaling; Myocyte; Endocrinology; Internal medicine; Biochemistry; Phosphorylation; Medicine; Gene","score_opus":0.015585389306105155,"score_gpt":0.25262533312129487,"score_spread":0.23703994381518972,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2135820246","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00030911286,0.9974125,0.00023020069,0.0004334694,0.00030246412,0.000003835761,0.0000067549818,0.0000065946397,0.0012951198],"genre_scores_gemma":[0.0019791573,0.9962508,0.0001684716,0.00024296955,0.00025984648,0.0000035419384,0.000011130934,0.0000012124142,0.0010828931],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977845,0.000026009411,0.00003108691,0.00005780862,0.00008623149,0.000020337235],"domain_scores_gemma":[0.9997172,0.00010546284,0.000027203088,0.0000102832355,0.00010786657,0.000032050473],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006233764,0.00076075323,0.00066750724,0.001439659,0.0004551933,0.00084735744,0.00084158557,0.0013271967,0.0014783189],"category_scores_gemma":[0.0004904021,0.00022362395,0.00021564963,0.0019456614,0.0011545721,0.0014415763,0.00044101154,0.0013547672,0.0012275091],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010666975,0.000074498676,0.00047690043,0.010615838,0.00005723026,0.0007833718,0.00020738311,0.0007893002,0.014096363,0.010980227,0.029982425,0.93182975],"study_design_scores_gemma":[0.000020636764,0.00010735541,0.0018282648,0.0015064144,0.000057154746,0.0024578795,0.000121098645,0.00020042062,0.0034559222,0.0051424485,0.98507744,0.000025055862],"about_ca_topic_score_codex":0.0034758847,"about_ca_topic_score_gemma":0.004867639,"teacher_disagreement_score":0.0034758847,"about_ca_system_score_codex":0.0015698292,"about_ca_system_score_gemma":0.0015508949,"threshold_uncertainty_score":0.011389911},"labels":[],"label_agreement":null},{"id":"W2136997869","doi":"10.1210/me.2007-0384","title":"SH2B1β (SH2-Bβ) Enhances Expression of a Subset of Nerve Growth Factor-Regulated Genes Important for Neuronal Differentiation Including Genes Encoding Urokinase Plasminogen Activator Receptor and Matrix Metalloproteinase 3/10","year":2007,"lang":"en","type":"article","venue":"Molecular Endocrinology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences","keywords":"Biology; Gene; Cell biology; Matrix metalloproteinase; Molecular biology; Cancer research; Genetics","score_opus":0.018933423516511134,"score_gpt":0.27836006126523244,"score_spread":0.2594266377487213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2136997869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949704,0.0022833138,0.00080228865,0.00006906419,0.000026865464,0.000019946447,0.0006364743,0.000059051312,0.0011325927],"genre_scores_gemma":[0.9883956,0.002382475,0.0015121772,0.00011704164,0.000024769412,0.000056115812,0.0022709605,0.000025990768,0.0052150013],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998598,0.000012827137,0.000008756912,0.000030912,0.00003388472,0.000053874784],"domain_scores_gemma":[0.99992263,0.00001130738,0.000022891518,0.000005361136,0.0000068956424,0.00003084774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009274027,0.00049702206,0.00027817202,0.00027073483,0.00014672718,0.00021164348,0.00009850858,0.00016275008,0.0026667363],"category_scores_gemma":[0.00005891522,0.00014312593,0.00029625918,0.00018992485,0.00016721895,0.00010845524,0.0001692769,0.00044282948,0.00056912296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011734624,0.00003498959,0.00016789639,0.000034929777,0.0000063579037,0.000015977977,0.000008184525,0.000017134334,0.9986858,0.00000987566,0.00004596778,0.0008555957],"study_design_scores_gemma":[0.00003017266,0.0008283516,0.024466567,0.000012474541,0.000035415673,0.00026923986,0.000049777675,0.0004774516,0.97021896,0.000027594488,0.0035782077,0.0000058081196],"about_ca_topic_score_codex":0.0013276587,"about_ca_topic_score_gemma":0.002091386,"teacher_disagreement_score":0.0026667363,"about_ca_system_score_codex":0.0002098803,"about_ca_system_score_gemma":0.00014848707,"threshold_uncertainty_score":0.008921146},"labels":[],"label_agreement":null},{"id":"W2138487124","doi":"10.1161/circulationaha.110.011734","title":"Epidermal Growth Factor–Like Domain 7 Is a Novel Inhibitor of Neutrophil Adhesion to Coronary Artery Endothelial Cells Injured by Calcineurin Inhibition","year":2011,"lang":"en","type":"article","venue":"Circulation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network","funders":"","keywords":"Medicine; Cell adhesion molecule; Calcineurin; Intercellular Adhesion Molecule-1; Cell adhesion; Pharmacology; Molecular biology; Immunology; Internal medicine; Endocrinology; Biology; Cell; Biochemistry; Transplantation","score_opus":0.02111578692377054,"score_gpt":0.23001758628765007,"score_spread":0.20890179936387954,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138487124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99360716,0.0045437873,0.0008975725,0.00007832302,0.00002781047,0.00002483835,0.00010426386,0.000026487733,0.0006897075],"genre_scores_gemma":[0.9953858,0.0020644823,0.0008982694,0.000056882036,0.000015584043,0.000033257784,0.00040766518,0.000004655529,0.0011334129],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999411,0.000010532145,0.0000057863226,0.000009597881,0.000018015482,0.0000149203115],"domain_scores_gemma":[0.99996626,0.0000039854785,0.0000107827145,0.0000028848594,0.000005031577,0.000011075156],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009165747,0.00021642415,0.00019889961,0.00010009282,0.000104883584,0.00016180525,0.00016079386,0.00015132665,0.00079507165],"category_scores_gemma":[0.00005874478,0.00006305717,0.00022926701,0.000087894885,0.000113518174,0.00009531097,0.00010378937,0.0003137929,0.00014946652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019533472,0.000071295035,0.00023724795,0.00007408585,0.000012054386,0.000060724607,0.0000058134706,0.00003407479,0.9977465,0.000038520146,0.000041694282,0.0014826697],"study_design_scores_gemma":[0.000118171774,0.0014292174,0.009902469,0.0000147123465,0.000058309895,0.00066965114,0.000026814914,0.00083729037,0.98221946,0.000029303954,0.004688778,0.0000059037666],"about_ca_topic_score_codex":0.00020884785,"about_ca_topic_score_gemma":0.0005287144,"teacher_disagreement_score":0.00079507165,"about_ca_system_score_codex":0.0001587915,"about_ca_system_score_gemma":0.00016024071,"threshold_uncertainty_score":0.002659738},"labels":[],"label_agreement":null},{"id":"W2138783723","doi":"10.1152/ajpheart.01247.2005","title":"Decrease in density of <i>I</i><sub>Na</sub> is in the common final pathway to heart block in murine hearts overexpressing calcineurin","year":2006,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Calcineurin; Internal medicine; Endocrinology; Ryanodine receptor; Sudden death; Sodium channel; Medicine; Chemistry; Sodium; Calcium; Transplantation","score_opus":0.010503275030687936,"score_gpt":0.2422841529919872,"score_spread":0.23178087796129926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138783723","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9922881,0.0014441359,0.0031445234,0.00011703276,0.000029911036,0.000032866923,0.00048427793,0.00022436681,0.0022348112],"genre_scores_gemma":[0.99030006,0.0008597858,0.0029437852,0.000120982455,0.00002087478,0.000080734404,0.00079873187,0.000110601584,0.0047644344],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997545,0.000020897514,0.00003361101,0.000060461985,0.00006749719,0.000063034946],"domain_scores_gemma":[0.9994697,0.000043186305,0.00019127938,0.000043188487,0.00005815505,0.00019459627],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001760233,0.0004270994,0.00046103157,0.0005305181,0.00014640336,0.00034337136,0.00031778254,0.000517149,0.0019515305],"category_scores_gemma":[0.00015100377,0.0002678245,0.0003259749,0.00014347628,0.0003839149,0.00038055092,0.0003190895,0.0009808041,0.0006899633],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000055592478,0.000009894909,0.00017033474,0.000012843171,0.0000027715664,0.00003720096,0.000009974305,0.000009199913,0.999385,0.000030514619,0.000012609352,0.00026403807],"study_design_scores_gemma":[0.000016503009,0.0003441355,0.023719188,0.000009162429,0.000018906994,0.0004776185,0.00003880951,0.00049134664,0.9737897,0.00006027369,0.0010285601,0.0000058918363],"about_ca_topic_score_codex":0.00046712984,"about_ca_topic_score_gemma":0.0006172118,"teacher_disagreement_score":0.0019515305,"about_ca_system_score_codex":0.00034620988,"about_ca_system_score_gemma":0.00013829957,"threshold_uncertainty_score":0.0065284967},"labels":[],"label_agreement":null},{"id":"W2138841568","doi":"10.1007/s00401-011-0798-y","title":"Granular expression of prolyl-peptidyl isomerase PIN1 is a constant and specific feature of Alzheimer’s disease pathology and is independent of tau, Aβ and TDP-43 pathology","year":2011,"lang":"en","type":"article","venue":"Acta Neuropathologica","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; National Institutes of Health; National Institute for Health and Care Research; Alzheimer Society; Wellcome Trust","keywords":"PIN1; Progressive supranuclear palsy; Pathology; Neurodegeneration; Corticobasal degeneration; Peptidylprolyl isomerase; Frontotemporal lobar degeneration; Neuropathology; Neurofibrillary tangle; Alzheimer's disease; Senile plaques; Dementia with Lewy bodies; Lewy body; Tauopathy; Dementia; Neuroscience; Frontotemporal dementia; Medicine; Biology; Disease; Isomerase; Biochemistry","score_opus":0.02723293976707953,"score_gpt":0.23885282011909825,"score_spread":0.21161988035201873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2138841568","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98963296,0.0025824537,0.0036307045,0.00013334757,0.000056817906,0.000021990758,0.00061308936,0.00018376131,0.003144901],"genre_scores_gemma":[0.99485934,0.00093135703,0.0015046436,0.000045496658,0.00002601574,0.000022013126,0.00050514296,0.00003303289,0.0020731254],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99983215,0.0000118833295,0.000017131948,0.00005341593,0.000048332855,0.000036948197],"domain_scores_gemma":[0.9997286,0.000022005983,0.00012335595,0.000030663145,0.000032876054,0.000062473584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013638534,0.0004656217,0.0003099278,0.0010842636,0.0002946606,0.0006005384,0.00024227417,0.00028934452,0.0019226676],"category_scores_gemma":[0.00029125813,0.00029942987,0.00026778647,0.0004278545,0.0004179643,0.0005458145,0.00053057657,0.0005229977,0.00054472394],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00053392735,0.000027573036,0.0046201195,0.00010475066,0.000045816236,0.0016982664,0.00005350977,0.000033592038,0.987958,0.0002545003,0.00020195666,0.0044679972],"study_design_scores_gemma":[0.000060224233,0.00034819148,0.30852893,0.000040469058,0.00013483255,0.028233849,0.00031009238,0.0007952735,0.6553185,0.001488579,0.004704218,0.00003689926],"about_ca_topic_score_codex":0.0003718779,"about_ca_topic_score_gemma":0.00041761188,"teacher_disagreement_score":0.0019226676,"about_ca_system_score_codex":0.00019186603,"about_ca_system_score_gemma":0.000121730256,"threshold_uncertainty_score":0.006431937},"labels":[],"label_agreement":null},{"id":"W2139157185","doi":"10.1016/j.jmb.2003.10.056","title":"Structural and Functional Studies of FkpA from Escherichia coli, a cis/trans Peptidyl-prolyl Isomerase with Chaperone Activity","year":2003,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":130,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; Institut national de la recherche scientifique","keywords":"Chaperone (clinical); Periplasmic space; Protein subunit; Prolyl isomerase; Peptidylprolyl isomerase; Dimer; Isomerase; FKBP; Stereochemistry; Mutant; Protein folding; C-terminus; Escherichia coli; Chemistry; Biochemistry; Biology; Crystallography; Amino acid; Enzyme; PIN1; Gene","score_opus":0.019415891248052347,"score_gpt":0.27049074610059176,"score_spread":0.25107485485253944,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139157185","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99639624,0.00092228147,0.0012628312,0.00020925062,0.000021420334,0.000009347228,0.0004158099,0.000025101752,0.00073785475],"genre_scores_gemma":[0.9955877,0.0004948954,0.0014181811,0.0000589649,0.000009701454,0.000006325633,0.0012531971,0.000012755678,0.0011583238],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999292,0.00001098546,0.0000057716434,0.000011943735,0.000021594728,0.000020527339],"domain_scores_gemma":[0.99982506,0.000040763487,0.000033456545,0.000011109154,0.000045270852,0.000044297874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015824584,0.000397988,0.00025641537,0.00019772949,0.00036635337,0.00032577763,0.00044288818,0.00033151274,0.0006404479],"category_scores_gemma":[0.0003121188,0.00013365583,0.0002502309,0.00032398396,0.0003095008,0.0002675935,0.00014417556,0.00075250905,0.00021901919],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007052732,0.00017188184,0.0017479208,0.000117412594,0.000018622994,0.0006727758,0.00012806863,0.0017477558,0.98954916,0.0008813448,0.00034140286,0.0039184387],"study_design_scores_gemma":[0.000049589442,0.00038113052,0.017214602,0.000018394261,0.00006812575,0.002124226,0.00043470153,0.008758147,0.9621008,0.00030408142,0.008512589,0.000033576238],"about_ca_topic_score_codex":0.007506488,"about_ca_topic_score_gemma":0.004131688,"teacher_disagreement_score":0.007506488,"about_ca_system_score_codex":0.0005190797,"about_ca_system_score_gemma":0.00036873424,"threshold_uncertainty_score":0.014925599},"labels":[],"label_agreement":null},{"id":"W2139976750","doi":"10.1113/jphysiol.2003.043836","title":"Modulation of Ca<sup>2+</sup>‐dependent Cl<sup>−</sup> channels by calcineurin in rabbit coronary arterial myocytes","year":2003,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Canadian Institutes of Health Research; Royal Society; University of Pittsburgh; Wellcome Trust; Heart and Stroke Foundation of Canada","keywords":"Calcineurin; Myocyte; Dephosphorylation; Chemistry; Phosphatase; Intracellular; Patch clamp; Biophysics; Extracellular; Calmodulin; Endocrinology; Internal medicine; Biochemistry; Phosphorylation; Biology; Receptor; Enzyme; Medicine; Transplantation","score_opus":0.011852043802138926,"score_gpt":0.243783661285304,"score_spread":0.23193161748316507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2139976750","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955344,0.001999744,0.0013929863,0.0000744432,0.000018535733,0.000022138167,0.000088139735,0.000033064698,0.00083656085],"genre_scores_gemma":[0.99612063,0.0011028231,0.0017598928,0.00005196964,0.000023735689,0.0000401046,0.00015548093,0.000023233619,0.00072208705],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99975437,0.000037306178,0.00003738945,0.00005712443,0.00005691942,0.00005680955],"domain_scores_gemma":[0.9997813,0.000059298487,0.000058175512,0.000033106397,0.000031955962,0.000036185433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036723842,0.00029671937,0.0004051783,0.0001301802,0.00019194178,0.0006127108,0.00043727856,0.00032461563,0.00047472914],"category_scores_gemma":[0.00031452012,0.00022014136,0.0003201157,0.00017175061,0.00048796032,0.00044580834,0.00026385544,0.0005782163,0.0002599997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058867074,0.000003916222,0.00007478411,0.000019532132,0.0000016481235,0.000029700152,0.000020867154,0.0000130031185,0.99958915,0.000027947075,0.0000037348825,0.00015687574],"study_design_scores_gemma":[0.000038881495,0.0002188454,0.005048436,0.000005593286,0.000023240527,0.0001565795,0.0000475151,0.0010327502,0.9923079,0.000033196582,0.0010822765,0.000004864307],"about_ca_topic_score_codex":0.0010887105,"about_ca_topic_score_gemma":0.0010857555,"teacher_disagreement_score":0.0010887105,"about_ca_system_score_codex":0.00044763746,"about_ca_system_score_gemma":0.000233433,"threshold_uncertainty_score":0.0032477975},"labels":[],"label_agreement":null},{"id":"W2140566350","doi":"10.1039/c2mb25107h","title":"A novel calcineurin-independent activity of cyclosporin A in <b> <i>Saccharomyces cerevisiae</i> </b>","year":2012,"lang":"en","type":"article","venue":"Molecular BioSystems","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto; University of New Brunswick","funders":"Canadian Institutes of Health Research","keywords":"Calcineurin; Saccharomyces cerevisiae; Computational biology; Biology; Chemistry; Biochemistry; Yeast; Medicine; Transplantation; Internal medicine","score_opus":0.013718078430799308,"score_gpt":0.25600334158592564,"score_spread":0.24228526315512633,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140566350","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98592836,0.0042650867,0.003922369,0.0001549551,0.00009351224,0.00006816285,0.00075893255,0.00019056277,0.004617979],"genre_scores_gemma":[0.993997,0.0011477771,0.00243337,0.00008707413,0.000019011111,0.0000271854,0.00065286417,0.000029236133,0.0016064907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988544,0.000018539124,0.00001698323,0.000027351507,0.000035568257,0.000016210488],"domain_scores_gemma":[0.9998777,0.000021345952,0.000024965631,0.000018833243,0.000018809442,0.00003837851],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010873898,0.00031089433,0.00023690074,0.00019114677,0.00015959721,0.0003882913,0.00023931236,0.00023386051,0.0011864937],"category_scores_gemma":[0.00011498347,0.00007359296,0.00028583632,0.00025398514,0.00014377071,0.00014247844,0.00015611255,0.00041497426,0.00027107683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008639546,0.000026246478,0.0000964325,0.00003176318,0.0000054822453,0.000041754258,0.0000040005207,0.00003457607,0.9983846,0.000055237757,0.000034145618,0.0011994023],"study_design_scores_gemma":[0.000019999236,0.00029505318,0.0015670089,0.0000032874525,0.000016451753,0.00018015817,0.0000071074555,0.00025054024,0.99548423,0.000016744189,0.0021560146,0.0000032244914],"about_ca_topic_score_codex":0.00096551946,"about_ca_topic_score_gemma":0.0013119145,"teacher_disagreement_score":0.0011864937,"about_ca_system_score_codex":0.00022235721,"about_ca_system_score_gemma":0.00031462446,"threshold_uncertainty_score":0.0039691925},"labels":[],"label_agreement":null},{"id":"W2140840746","doi":"10.1371/journal.pone.0057644","title":"Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase","year":2013,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Ministero dello Sviluppo Economico; Ontario Ministry of Economic Development and Innovation; Canadian Institutes of Health Research; Genome Canada; Wellcome Trust; GlaxoSmithKline; Pfizer; Eli Lilly and Company","keywords":"Allosteric regulation; Active site; Cyclase; Adenylate kinase; Protein subunit; Chemistry; GUCY1A3; Protein structure; Biochemistry; Stereochemistry; GUCY1B3; Binding site; Enzyme; Biophysics; Guanylate cyclase 2C; Biology","score_opus":0.02068693335948622,"score_gpt":0.22458980704848905,"score_spread":0.20390287368900284,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2140840746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8643499,0.03558862,0.01998461,0.003668828,0.00085167703,0.0004447452,0.03266588,0.0010956973,0.041350033],"genre_scores_gemma":[0.8122834,0.012866119,0.043716256,0.0010411955,0.00012585976,0.00045994148,0.11037529,0.0002171934,0.018914843],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997397,0.00004246442,0.00001755271,0.00004605822,0.0001191778,0.000035115114],"domain_scores_gemma":[0.99973065,0.00006808655,0.00003419469,0.000018939254,0.00009547322,0.000052674153],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003382336,0.00049418426,0.00063780276,0.00026110394,0.00069227145,0.0006901622,0.00061366544,0.00075300864,0.0036959809],"category_scores_gemma":[0.00077332853,0.00040654247,0.00028955564,0.00093447143,0.00025518713,0.00046689034,0.0002513437,0.0013882826,0.0009747471],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003246977,0.0011935037,0.013648132,0.0023928778,0.000507331,0.0026314578,0.0017869074,0.032759868,0.7233864,0.025292018,0.109986335,0.08316823],"study_design_scores_gemma":[0.0025775977,0.00095567544,0.06800187,0.00043677367,0.00053994404,0.0044574286,0.0015572687,0.13644831,0.25762597,0.014375951,0.51269186,0.00033140767],"about_ca_topic_score_codex":0.009364653,"about_ca_topic_score_gemma":0.010106665,"teacher_disagreement_score":0.009364653,"about_ca_system_score_codex":0.0014046945,"about_ca_system_score_gemma":0.0011502974,"threshold_uncertainty_score":0.018620312},"labels":[],"label_agreement":null},{"id":"W2141136085","doi":"10.3109/01902140902870741","title":"EXPRESSION AND ACTIVITIES OF<i>N</i>-MYRISTOYLTRANSFERASE AND CALCINEURIN IN NORMAL AND INFLAMED LUNGS","year":2009,"lang":"en","type":"article","venue":"Experimental Lung Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"Calcineurin; Inflammation; Lung; Biology; Epithelium; Pharmacology; Immunology; Endocrinology; Internal medicine; Pathology; Medicine; Transplantation","score_opus":0.01733399582606654,"score_gpt":0.34822138886962034,"score_spread":0.3308873930435538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141136085","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963308,0.0016517363,0.0012653148,0.000042851974,0.000010052616,0.000009595512,0.00013478796,0.000025603704,0.00052925217],"genre_scores_gemma":[0.995843,0.0009450348,0.0015902971,0.000027153726,0.000009524113,0.000033823988,0.00029459174,0.0000074341065,0.0012490881],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998098,0.000024186165,0.000017068762,0.00005973029,0.000047547623,0.000041688756],"domain_scores_gemma":[0.99982125,0.0000194262,0.000072605944,0.000014794409,0.000021333184,0.000050642182],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017484232,0.00024171144,0.0001722717,0.00041692887,0.00013337562,0.00022854001,0.0001498084,0.00025812845,0.0008015778],"category_scores_gemma":[0.00016672112,0.00015853113,0.00020939556,0.00015880012,0.00043032257,0.0003093297,0.00017158496,0.00035115393,0.00012459894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010907465,0.000007857428,0.00048019495,0.000014927012,0.0000022956704,0.00002697162,0.0000104756755,0.000006885878,0.9990392,0.000022060442,0.0000030624865,0.00027702877],"study_design_scores_gemma":[0.00001871642,0.00059762143,0.076012164,0.000008296131,0.000029924071,0.00072612014,0.00010588961,0.0005826251,0.9208225,0.00011068451,0.0009752222,0.000010082596],"about_ca_topic_score_codex":0.00048702632,"about_ca_topic_score_gemma":0.00051405793,"teacher_disagreement_score":0.0008015778,"about_ca_system_score_codex":0.00021964363,"about_ca_system_score_gemma":0.0001684904,"threshold_uncertainty_score":0.0026814938},"labels":[],"label_agreement":null},{"id":"W2141711177","doi":"10.1093/intimm/dxl050","title":"Binding of multivalent CD147 phage induces apoptosis of U937 cells","year":2006,"lang":"en","type":"article","venue":"International Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Annexin; Apoptosis; Flow cytometry; Extracellular; Cell biology; Cell; Molecular biology; Programmed cell death; Biology; Receptor; Phage display; Cell culture; U937 cell; Chemistry; Antibody; Biochemistry; Immunology","score_opus":0.009289453422263172,"score_gpt":0.24988424225461375,"score_spread":0.24059478883235058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2141711177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949498,0.0014638257,0.0017068097,0.000080662736,0.000042526914,0.000031376883,0.00021276562,0.00006114154,0.0014509984],"genre_scores_gemma":[0.99549073,0.0006783417,0.0014341662,0.0000954922,0.000016366932,0.000041578314,0.00057249604,0.000012147548,0.0016586755],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996549,0.000057270383,0.000032679483,0.00004242139,0.00011518449,0.000097504046],"domain_scores_gemma":[0.9998603,0.000048607635,0.00001891568,0.000025805795,0.000024127348,0.000022204187],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013338008,0.00040721506,0.0004982912,0.00027123865,0.00022551803,0.0003368698,0.00014054202,0.00034609306,0.0010778373],"category_scores_gemma":[0.00016632606,0.00013289714,0.00033431302,0.00026787483,0.00015436248,0.00012367683,0.00027571435,0.00059819594,0.00033710268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023059834,0.00006367088,0.00024468114,0.00003947383,0.000012220985,0.000116408395,0.00005113372,0.000058618614,0.99758923,0.00006628854,0.000071598224,0.0014559774],"study_design_scores_gemma":[0.000025241949,0.0006529351,0.0042752107,0.000008500682,0.000020371393,0.00027620269,0.000073063755,0.0008280219,0.99240667,0.00005902956,0.0013703754,0.000004467122],"about_ca_topic_score_codex":0.0007531066,"about_ca_topic_score_gemma":0.0007473158,"teacher_disagreement_score":0.0010778373,"about_ca_system_score_codex":0.0002792575,"about_ca_system_score_gemma":0.00014122498,"threshold_uncertainty_score":0.0036057234},"labels":[],"label_agreement":null},{"id":"W2142285130","doi":"10.1152/ajpheart.00246.2010","title":"Early activation of matrix metalloproteinases underlies the exacerbated systolic and diastolic dysfunction in mice lacking TIMP3 following myocardial infarction","year":2010,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Alberta","funders":"Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; University of Alberta; National Heart, Lung, and Blood Institute; Heart and Stroke Foundation of Canada","keywords":"Matrix metalloproteinase; Cardiology; Diastole; Internal medicine; Myocardial infarction; Medicine; Blood pressure","score_opus":0.008109540693005183,"score_gpt":0.240931937873639,"score_spread":0.23282239718063383,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142285130","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.992432,0.0008682887,0.003459205,0.00028902368,0.000069187496,0.000057632937,0.0015624025,0.00028634517,0.000975842],"genre_scores_gemma":[0.98984295,0.00093248254,0.00298822,0.00021271652,0.00004318632,0.00020062839,0.0012361429,0.0001233244,0.004420384],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997073,0.000032935037,0.00005224847,0.00006535152,0.000058025045,0.00008416202],"domain_scores_gemma":[0.99934334,0.00002902181,0.00030680443,0.000032928132,0.000028708982,0.00025919802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031125406,0.0009475739,0.0006523407,0.0007805902,0.0003429104,0.0005152595,0.00038154097,0.000784866,0.0032978144],"category_scores_gemma":[0.00023766926,0.00053010235,0.00075339735,0.0003552719,0.0006090396,0.00042289673,0.00035401827,0.0018686117,0.0009832779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007606673,0.00011663615,0.0005025156,0.000042865136,0.000010715824,0.0002429622,0.000037208363,0.00004744566,0.9973918,0.00009792091,0.000084698,0.00066446245],"study_design_scores_gemma":[0.0005279642,0.0034654767,0.10288374,0.00011768345,0.00018903942,0.005520181,0.0004000938,0.0037031802,0.8782838,0.0006212386,0.004219528,0.00006800844],"about_ca_topic_score_codex":0.00066076353,"about_ca_topic_score_gemma":0.0011007232,"teacher_disagreement_score":0.0032978144,"about_ca_system_score_codex":0.00048719512,"about_ca_system_score_gemma":0.00035258412,"threshold_uncertainty_score":0.011032283},"labels":[],"label_agreement":null},{"id":"W2142566329","doi":"10.1007/s12079-009-0057-3","title":"Periostin localizes to cells in normal skin, but is associated with the extracellular matrix during wound repair","year":2009,"lang":"en","type":"article","venue":"Journal of Cell Communication and Signaling","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":87,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Institute of Musculoskeletal Health and Arthritis; Canadian Institutes of Health Research","keywords":"Periostin; Matricellular protein; Extracellular matrix; Wound healing; Cell biology; Pathology; Decorin; Skin repair; Myofibroblast; Biology; Medicine; Immunology; Fibrosis","score_opus":0.007828668616243385,"score_gpt":0.23573543627699958,"score_spread":0.2279067676607562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2142566329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9857584,0.007431983,0.0039727557,0.00014586552,0.000052324176,0.000017447686,0.00017436485,0.00007492448,0.0023719557],"genre_scores_gemma":[0.99160516,0.0022348475,0.0021888635,0.00006510284,0.000032054533,0.000030239647,0.00032632108,0.000016134396,0.0035012362],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998357,0.000024531342,0.00000922137,0.000047955295,0.000052143074,0.000030483665],"domain_scores_gemma":[0.9998122,0.000025445663,0.00006193279,0.000019477779,0.000026312902,0.000054553584],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001242647,0.00021324286,0.00017195282,0.0004319608,0.00025104004,0.0003632043,0.0000953466,0.00027959372,0.0014623725],"category_scores_gemma":[0.00016766266,0.0001236964,0.00014943433,0.0002732544,0.00031303932,0.0003476375,0.00023065315,0.00037485012,0.00043389117],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008631226,0.000006770409,0.0006635198,0.00003440764,0.0000021099377,0.00013000946,0.00002110637,0.000009974928,0.99703693,0.000099183584,0.0000330667,0.0018766024],"study_design_scores_gemma":[0.000021893662,0.0005002296,0.10991885,0.000047234196,0.00003519902,0.0058314493,0.00028510866,0.0006748654,0.8695823,0.0006511922,0.012439879,0.000011848492],"about_ca_topic_score_codex":0.00020105878,"about_ca_topic_score_gemma":0.00027805244,"teacher_disagreement_score":0.0014623725,"about_ca_system_score_codex":0.00024197383,"about_ca_system_score_gemma":0.00021204057,"threshold_uncertainty_score":0.004892111},"labels":[],"label_agreement":null},{"id":"W2144353020","doi":"10.1002/jcp.10251","title":"β‐adrenergic receptor‐mediated DNA synthesis in neonatal rat cardiac fibroblasts proceeds via a phosphatidylinositol 3‐kinase dependent pathway refractory to the antiproliferative action of cyclic AMP","year":2003,"lang":"en","type":"article","venue":"Journal of Cellular Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal; Institut Universitaire de Gériatrie de Montréal; Montreal Heart Institute","funders":"","keywords":"Kinase; Cell biology; Phosphorylation; Signal transduction; DNA synthesis; Protein kinase A; Phosphatidylinositol; Ribosomal protein s6; Biology; Ribosomal s6 kinase; PI3K/AKT/mTOR pathway; Forskolin; P70-S6 Kinase 1; Molecular biology; Biochemistry; Receptor; DNA","score_opus":0.010101534561619987,"score_gpt":0.2339422215343894,"score_spread":0.2238406869727694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144353020","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865884,0.006063489,0.0037495375,0.00007293679,0.000040023202,0.00004042283,0.00062586705,0.0000622199,0.0027570855],"genre_scores_gemma":[0.9861622,0.0052661984,0.0038920548,0.00007003868,0.000020340181,0.0001079968,0.0011155163,0.000015621825,0.0033501508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992895,0.000010357576,0.000009153762,0.000015556676,0.00002146512,0.000014543612],"domain_scores_gemma":[0.9999268,0.000015778101,0.000018816198,0.000012232938,0.000011200393,0.000015083768],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013393383,0.0003469199,0.00018089816,0.00020191022,0.00013142233,0.00015879875,0.00010663834,0.0001485974,0.0008300842],"category_scores_gemma":[0.0000783236,0.00011952288,0.0002505343,0.000112094625,0.00012250427,0.00015239268,0.000106369014,0.0003243335,0.0004564895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004135093,0.000008258039,0.00006433187,0.000019584817,0.0000011461026,0.000030674088,0.000006577457,0.000008595614,0.9991855,0.000022202708,0.000006011411,0.0006056942],"study_design_scores_gemma":[0.000011359416,0.00026128005,0.008152544,0.0000072889093,0.000010481824,0.0002733776,0.000027962009,0.00022251064,0.98959863,0.000036269932,0.0013950239,0.0000032258638],"about_ca_topic_score_codex":0.0005678221,"about_ca_topic_score_gemma":0.0011427548,"teacher_disagreement_score":0.0008300842,"about_ca_system_score_codex":0.00015919581,"about_ca_system_score_gemma":0.00021535068,"threshold_uncertainty_score":0.0027769208},"labels":[],"label_agreement":null},{"id":"W2144632351","doi":"10.1128/mcb.21.18.6102-6112.2001","title":"Synergistic Regulation of Immunoreceptor Signaling by SLP-76-Related Adaptor Clnk and Serine/Threonine Protein Kinase HPK-1","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":49,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre; Montreal Clinical Research Institute","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Biology; Signal transducing adaptor protein; Serine; Threonine; Protein-Serine-Threonine Kinases; Phosphorylation; Cell biology; Signal transduction; Kinase; Protein kinase A; AKT3","score_opus":0.00427172121766067,"score_gpt":0.20167637538848018,"score_spread":0.1974046541708195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144632351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9959571,0.001937192,0.0008033961,0.00007198121,0.000024760893,0.00001601004,0.00008000693,0.00004287836,0.0010664955],"genre_scores_gemma":[0.9975067,0.0005373664,0.00073978066,0.000033827804,0.000012052109,0.000023658491,0.00014101386,0.0000061050796,0.0009995358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997503,0.000049322345,0.000016842427,0.000040497933,0.00004881085,0.00009419464],"domain_scores_gemma":[0.9998727,0.000020056963,0.000032118372,0.000011337676,0.000010121541,0.000053762407],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015073619,0.00041509414,0.00028346715,0.00022115496,0.00015169737,0.0003884464,0.0001971871,0.00018252457,0.0011372811],"category_scores_gemma":[0.00017342324,0.0001409976,0.0002593963,0.00013571282,0.00021670185,0.00029082247,0.00080030697,0.00042833542,0.00038426422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035872567,0.000029320148,0.00049768895,0.00006664862,0.000007499507,0.00022294461,0.000014076685,0.000120683675,0.997209,0.0001007431,0.00004825858,0.0013243712],"study_design_scores_gemma":[0.00013380648,0.00053288863,0.034228858,0.00001937653,0.000052880703,0.0009990177,0.00013753356,0.0066830516,0.9537328,0.00020166888,0.0032585147,0.000019685776],"about_ca_topic_score_codex":0.00017709688,"about_ca_topic_score_gemma":0.00030682582,"teacher_disagreement_score":0.0011372811,"about_ca_system_score_codex":0.00034422617,"about_ca_system_score_gemma":0.00017149582,"threshold_uncertainty_score":0.003804624},"labels":[],"label_agreement":null},{"id":"W2144661082","doi":"10.1152/jn.2000.83.6.3388","title":"Mechanisms Involved in Tetanus-Induced Potentiation of Fast IPSCs in Rat Hippocampal CA1 Neurons","year":2000,"lang":"en","type":"article","venue":"Journal of Neurophysiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Long-term potentiation; Neuroscience; Hippocampal formation; Hippocampus; Induced pluripotent stem cell; Chemistry; Psychology; Biology; Receptor; Biochemistry","score_opus":0.014245035178192962,"score_gpt":0.23933846215148094,"score_spread":0.225093426973288,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2144661082","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9899048,0.0047146035,0.003094631,0.00010394254,0.00003791019,0.00006922369,0.00026477556,0.0001219199,0.0016882243],"genre_scores_gemma":[0.9941439,0.0028359424,0.0013072254,0.00006919648,0.000023741804,0.00007178545,0.0002293063,0.000012052995,0.0013069612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991786,0.0000062697936,0.000010167878,0.000016049951,0.000024971945,0.00002480376],"domain_scores_gemma":[0.9999188,0.0000123273385,0.000025201693,0.000011691342,0.000016394424,0.000015605166],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009152978,0.00038900858,0.0004079875,0.00022811657,0.00015287996,0.00017279763,0.00023290367,0.0003447513,0.001092854],"category_scores_gemma":[0.00011443426,0.00016462879,0.00043053678,0.00012848794,0.00018773494,0.00037033047,0.0002623456,0.0005480267,0.0002815054],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000070076814,0.000010304412,0.00012666904,0.000085452775,0.000005902165,0.00016924104,0.000011508587,0.000025690873,0.99841094,0.00005353136,0.00000872841,0.0010218564],"study_design_scores_gemma":[0.000048283677,0.00058359664,0.04914973,0.000024972964,0.00007106906,0.0008421446,0.000056755947,0.0010021895,0.9471319,0.00029409843,0.0007803828,0.000014900082],"about_ca_topic_score_codex":0.0006151968,"about_ca_topic_score_gemma":0.00092531746,"teacher_disagreement_score":0.001092854,"about_ca_system_score_codex":0.00027189215,"about_ca_system_score_gemma":0.00019429353,"threshold_uncertainty_score":0.00365597},"labels":[],"label_agreement":null},{"id":"W2145113162","doi":"10.1016/j.ajpath.2013.01.041","title":"Expression of Myoferlin in Human and Murine Carcinoma Tumors","year":2013,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; University of British Columbia","funders":"British Columbia Knowledge Development Fund; Michael Smith Health Research BC; Heart and Stroke Foundation of British Columbia and Yukon; Canada Foundation for Innovation; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Expression (computer science); Carcinoma; Cancer research; Biology; Internal medicine; Medicine; Computer science; Programming language","score_opus":0.006745298215855,"score_gpt":0.24725387715919456,"score_spread":0.24050857894333955,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145113162","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99534565,0.001570578,0.0011872083,0.00006138798,0.000012857622,0.000013162268,0.00036215558,0.000037294107,0.0014097842],"genre_scores_gemma":[0.99488884,0.0006231981,0.000970234,0.000022205044,0.000004854995,0.00001882337,0.00056772283,0.000013884924,0.0028902206],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998778,0.000016730535,0.000009349416,0.000025548125,0.000029816076,0.000040844985],"domain_scores_gemma":[0.9998933,0.000028406379,0.000025573849,0.000015214383,0.000009051869,0.000028418408],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016048353,0.00021532581,0.00013228772,0.0006231127,0.00030132596,0.00030353921,0.00012495124,0.00024850905,0.0016277132],"category_scores_gemma":[0.00016826997,0.00020786446,0.00015624688,0.00022789484,0.00021715359,0.00024382657,0.00017469618,0.00027896906,0.00026082573],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022460331,0.000014659096,0.0006022646,0.000014565534,0.0000057103025,0.00009838147,0.000031829833,0.00005438164,0.99800867,0.00033790604,0.000036047775,0.0005709864],"study_design_scores_gemma":[0.000029716277,0.00047438926,0.03634593,0.000009248263,0.000050940595,0.0018573375,0.00015891368,0.001287845,0.95511276,0.00017696583,0.0044879657,0.000008052551],"about_ca_topic_score_codex":0.0017246159,"about_ca_topic_score_gemma":0.002063353,"teacher_disagreement_score":0.0017246159,"about_ca_system_score_codex":0.0004153215,"about_ca_system_score_gemma":0.00023390645,"threshold_uncertainty_score":0.005445242},"labels":[],"label_agreement":null},{"id":"W2145208368","doi":"10.1523/jneurosci.20-01-00230.2000","title":"The Urokinase Plasminogen Activator Receptor (UPAR) Is Preferentially Induced by Nerve Growth Factor in PC12 Pheochromocytoma Cells and Is Required for NGF-Driven Differentiation","year":2000,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Royal Victoria Hospital","funders":"National Institute of Neurological Disorders and Stroke; Medical Research Council; National Institutes of Health","keywords":"Urokinase receptor; Nerve growth factor; Epidermal growth factor; Neurotrophin; Biology; Cellular differentiation; Receptor; Cell biology; Endocrinology; Plasminogen activator; Gene; Biochemistry","score_opus":0.024394299231329835,"score_gpt":0.2611775908536442,"score_spread":0.2367832916223144,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2145208368","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9813083,0.0026627432,0.012730865,0.00019263718,0.0000805292,0.000047542468,0.00089713157,0.00026559347,0.0018147683],"genre_scores_gemma":[0.9800016,0.0020831556,0.010133172,0.0000668813,0.000023403505,0.00008624004,0.001593443,0.0000986272,0.005913545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99957424,0.000037211266,0.000048005662,0.00008502584,0.00014647807,0.000108995046],"domain_scores_gemma":[0.99946433,0.00011155103,0.00013083155,0.00006780504,0.00007552558,0.00014992262],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016128737,0.00036571428,0.00064036215,0.0005598406,0.00037798384,0.00066779385,0.00029030832,0.0003052913,0.001261786],"category_scores_gemma":[0.00026934224,0.00032980196,0.00050074235,0.0004119443,0.00038917697,0.0003346102,0.00044792838,0.0009662768,0.0010345638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000032871874,0.0000057428524,0.000084713225,0.000013757927,0.0000019577851,0.000056444143,0.0000087547005,0.000008427909,0.9993956,0.00003582406,0.000010060476,0.00034582807],"study_design_scores_gemma":[0.0000065121126,0.000075559234,0.0055023436,0.0000031803825,0.000011636596,0.00037525533,0.000033140128,0.00018965379,0.9924965,0.00003063742,0.0012700936,0.0000055666],"about_ca_topic_score_codex":0.0022522823,"about_ca_topic_score_gemma":0.003145882,"teacher_disagreement_score":0.0022522823,"about_ca_system_score_codex":0.0005494839,"about_ca_system_score_gemma":0.0003877775,"threshold_uncertainty_score":0.0044783354},"labels":[],"label_agreement":null},{"id":"W2146565556","doi":"10.1096/fj.09-134296","title":"Degradation of regulator of calcineurin 1 (RCAN1) is mediated by both chaperone‐mediated autophagy and ubiquitin proteasome pathways","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":122,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Canadian HIV Trials Network, Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Autophagy; Proteasome; Cell biology; Lysosome; Ubiquitin; Regulator; Protein degradation; Calcineurin; Endoplasmic-reticulum-associated protein degradation; Biology; Proteasome inhibitor; F-box protein; Chemistry; Ubiquitin ligase; Biochemistry; Gene; Enzyme; Medicine","score_opus":0.011846173925689152,"score_gpt":0.22970392210148605,"score_spread":0.2178577481757969,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146565556","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97812724,0.015221868,0.0036244346,0.00022254564,0.0000458763,0.000027808112,0.00015246608,0.00013049724,0.0024473919],"genre_scores_gemma":[0.99044704,0.004090303,0.002140797,0.00004928251,0.000026281146,0.000024061892,0.00029096726,0.000011859948,0.0029192655],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998772,0.000019406769,0.000007904713,0.000036313784,0.000035786983,0.000023429087],"domain_scores_gemma":[0.99988043,0.00001536317,0.000041321044,0.000013675027,0.000025335476,0.000023740313],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020280184,0.00043043174,0.0001949932,0.00030679774,0.00027185664,0.0004013616,0.00016197721,0.00018676653,0.00056455634],"category_scores_gemma":[0.00015558055,0.00009389361,0.00019223869,0.00013536916,0.00023749529,0.00024200477,0.00019698094,0.00022737373,0.00020004436],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000872305,0.0000196198,0.0006359147,0.00005626887,0.0000074603777,0.00013339758,0.00001593646,0.00009385844,0.9955324,0.00031478287,0.00008109536,0.003022038],"study_design_scores_gemma":[0.000018985327,0.0001790732,0.012426867,0.000012189094,0.000032320644,0.0010102991,0.000030367415,0.0020833951,0.9775184,0.00024654574,0.0064331517,0.000008572926],"about_ca_topic_score_codex":0.0007536009,"about_ca_topic_score_gemma":0.0012354532,"teacher_disagreement_score":0.0007536009,"about_ca_system_score_codex":0.00052376895,"about_ca_system_score_gemma":0.00034950938,"threshold_uncertainty_score":0.003800273},"labels":[],"label_agreement":null},{"id":"W2146583324","doi":"10.1111/j.1582-4934.2009.00715.x","title":"Calcineurin inhibition enhances motor neuron survival following injury","year":2009,"lang":"en","type":"article","venue":"Journal of Cellular and Molecular Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University; University of Toronto","funders":"","keywords":"Neuroprotection; Calcineurin; Pharmacology; Motor neuron; Neuroscience; Biology; Medicine; Transplantation; Internal medicine","score_opus":0.00801765360578331,"score_gpt":0.2599334572816816,"score_spread":0.2519158036758983,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2146583324","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952194,0.0018269471,0.00076089194,0.00007872336,0.000030417319,0.000020504318,0.00010796719,0.00008946272,0.0018656349],"genre_scores_gemma":[0.99362963,0.0021568115,0.0013213315,0.00003205877,0.000022359422,0.00003636669,0.00023868981,0.000014754849,0.0025479875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986076,0.000015819669,0.000013562233,0.000025470692,0.000041581094,0.000042759977],"domain_scores_gemma":[0.9998857,0.000017229931,0.00003486691,0.000013444944,0.000014256951,0.000034348715],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014191818,0.0004051226,0.00040259326,0.00037349283,0.00018128564,0.00031861677,0.0002604627,0.00027273828,0.0011436582],"category_scores_gemma":[0.00012055798,0.00008186482,0.00025614144,0.00020546521,0.0002598094,0.00023225971,0.00019959605,0.00058459083,0.00023400325],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018422186,0.00007444713,0.0000922643,0.000054039625,0.0000076028746,0.00003919147,0.000016171167,0.0000623436,0.99688196,0.000063484025,0.00003576819,0.0024885777],"study_design_scores_gemma":[0.000028294631,0.0013454832,0.005180001,0.000012889406,0.000033231518,0.00016418312,0.000024947003,0.0005439044,0.9914962,0.000042550193,0.0011248076,0.0000036514375],"about_ca_topic_score_codex":0.0007864712,"about_ca_topic_score_gemma":0.002560374,"teacher_disagreement_score":0.0011436582,"about_ca_system_score_codex":0.00029686763,"about_ca_system_score_gemma":0.00034488674,"threshold_uncertainty_score":0.0038259625},"labels":[],"label_agreement":null},{"id":"W2147001533","doi":"10.1096/fj.05-4028fje","title":"NF‐κB and AP‐1 differentially contribute to the induction of Mn‐SOD and eNOS during the development of oxidant tolerance","year":2005,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Enos; Transcription factor; Cell biology; Chromosomal translocation; Myocyte; Chemistry; NF-κB; Pro-oxidant; NFKB1; Biology; Signal transduction; Nitric oxide synthase; Reactive oxygen species; Biochemistry; Enzyme","score_opus":0.009465600623726663,"score_gpt":0.22547847758290548,"score_spread":0.2160128769591788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147001533","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98667395,0.004588523,0.0069381665,0.00016789247,0.00010451289,0.000041768555,0.00014017137,0.00006633026,0.0012786255],"genre_scores_gemma":[0.99133474,0.0018316993,0.002826283,0.00009786216,0.000037411985,0.000088788016,0.00026516133,0.000014730937,0.003503172],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961,0.000053621927,0.000049061084,0.0001045908,0.00008285784,0.00009984074],"domain_scores_gemma":[0.9996457,0.000031195574,0.00010291071,0.000035002053,0.00005445261,0.00013064807],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003917401,0.00050871726,0.0004463662,0.00029664524,0.0002485337,0.0005146685,0.00033496384,0.0004304799,0.0015011473],"category_scores_gemma":[0.00028289124,0.00028189132,0.000459291,0.00014499103,0.0004519056,0.00051252724,0.00037779167,0.00096809084,0.000478321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019077293,0.00003958322,0.00028243902,0.000032439115,0.0000038461408,0.000064213455,0.000031141903,0.000017327395,0.9987256,0.0000752733,0.000009733841,0.00052759814],"study_design_scores_gemma":[0.00006429622,0.0010405706,0.032120045,0.000048481703,0.000059050948,0.0011202401,0.000338255,0.0011015049,0.96068066,0.00047505138,0.002934727,0.00001705787],"about_ca_topic_score_codex":0.00022898824,"about_ca_topic_score_gemma":0.00029709586,"teacher_disagreement_score":0.0015011473,"about_ca_system_score_codex":0.00026005277,"about_ca_system_score_gemma":0.00031919935,"threshold_uncertainty_score":0.0050218105},"labels":[],"label_agreement":null},{"id":"W2148489435","doi":"10.1034/j.1600-6143.2002.20305.x","title":"Activation-Induced Expression of Cell Surface CD28 on Mouse T Lymphocytes is Inhibited by Cyclosporine A","year":2002,"lang":"en","type":"article","venue":"American Journal of Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Research Nova Scotia","keywords":"CD28; T cell; IL-2 receptor; Interleukin 2; CD3; Flow cytometry; Molecular biology; Monoclonal antibody; Cell biology; Biology; Immunology; Cytokine; Antibody; Antigen; Immune system; CD8","score_opus":0.00896427496417032,"score_gpt":0.22452677435271712,"score_spread":0.2155624993885468,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148489435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99484336,0.0011692714,0.0009714015,0.00016925369,0.00006695285,0.000025972982,0.0002177316,0.000119414544,0.0024166114],"genre_scores_gemma":[0.99607986,0.00064399565,0.0005792021,0.00005508008,0.00003092121,0.000037922906,0.0003761358,0.00003373197,0.0021632162],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993649,0.00014492382,0.000040016643,0.000060959574,0.00012399314,0.00026515237],"domain_scores_gemma":[0.99950993,0.00014003112,0.000103284976,0.000076230375,0.000026352804,0.00014415276],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002744725,0.0008768293,0.00046804047,0.00054691365,0.00036467487,0.0007633119,0.00041360757,0.0004967315,0.0020545216],"category_scores_gemma":[0.0003100599,0.00031785405,0.00050107966,0.0004082462,0.00045882803,0.0003007964,0.00040101842,0.0026818628,0.0008622532],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048722472,0.000094481285,0.00015405675,0.00002687957,0.000008448382,0.000073520794,0.000016305756,0.00009664771,0.9979786,0.00020881084,0.00006850722,0.00078650704],"study_design_scores_gemma":[0.000077505996,0.00037292627,0.0037693377,0.0000093985545,0.000021524651,0.00018144416,0.00003336618,0.0011282484,0.9931443,0.00009023331,0.0011661357,0.000005637673],"about_ca_topic_score_codex":0.00055891264,"about_ca_topic_score_gemma":0.0012757521,"teacher_disagreement_score":0.0020545216,"about_ca_system_score_codex":0.0005261342,"about_ca_system_score_gemma":0.00045805852,"threshold_uncertainty_score":0.0068730116},"labels":[],"label_agreement":null},{"id":"W2148762097","doi":"10.1074/mcp.m100030-mcp200","title":"The Rickettsia prowazekii Invasion Gene Homolog (invA) Encodes a Nudix Hydrolase Active on Adenosine (5′)-pentaphospho-(5′)-adenosine","year":2002,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Institute of General Medical Sciences; Ministry of Defense","keywords":"Rickettsia prowazekii; Adenosine; Gene; Biology; Hydrolase; Cell biology; Biochemistry; Genetics; Enzyme; Rickettsia","score_opus":0.012412617783599082,"score_gpt":0.20849173532739024,"score_spread":0.19607911754379115,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2148762097","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9889677,0.0024146754,0.0050704745,0.00014263178,0.000047023394,0.00004187504,0.0018212835,0.00030669424,0.0011876554],"genre_scores_gemma":[0.96905154,0.0015708351,0.013709505,0.00006965079,0.000025427744,0.000060922008,0.010181885,0.000046497673,0.0052837366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999261,0.000005962633,0.000006341974,0.000023775023,0.000018856117,0.00001904581],"domain_scores_gemma":[0.99989486,0.000013998296,0.00003703949,0.0000075981366,0.000011034916,0.000035329784],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000829676,0.0006856851,0.000361844,0.00028446777,0.00018275426,0.00031410297,0.00013789386,0.00028008252,0.0010573389],"category_scores_gemma":[0.000120180586,0.00020232571,0.00034424814,0.00026363315,0.00019156314,0.0002020541,0.0002953508,0.0004554615,0.00090324495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006961897,0.000017996368,0.00081687426,0.00005212376,0.0000050407007,0.00013945994,0.000028090702,0.000040570878,0.99652535,0.00009641103,0.0000819169,0.0021265997],"study_design_scores_gemma":[0.000059475013,0.00057885423,0.081679955,0.000039130817,0.00005929808,0.0042994977,0.00025499373,0.0016587593,0.8828567,0.00034304714,0.028139042,0.0000312851],"about_ca_topic_score_codex":0.00046357978,"about_ca_topic_score_gemma":0.0004177305,"teacher_disagreement_score":0.0010573389,"about_ca_system_score_codex":0.00025702483,"about_ca_system_score_gemma":0.00021648729,"threshold_uncertainty_score":0.0035371184},"labels":[],"label_agreement":null},{"id":"W2151873866","doi":"10.1152/ajpcell.00518.2002","title":"Calcineurin-independent regulation of plasma membrane Ca<sup>2</sup><sup>+</sup> ATPase-4 in the vascular smooth muscle cell cycle","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Cell Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; Heart and Stroke Foundation; University of Toronto","funders":"","keywords":"Calcineurin; NFAT; Vascular smooth muscle; Calmodulin; BAPTA; Psychological repression; Plasma membrane Ca2+ ATPase; Cell biology; Molecular biology; Signal transduction; Biology; CAMK; Chemistry; Intracellular; ATPase; Biochemistry; Protein kinase A; Gene expression; Kinase; Internal medicine; Endocrinology; Transplantation; Enzyme","score_opus":0.006345844721638792,"score_gpt":0.2182289770648308,"score_spread":0.211883132343192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2151873866","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990932,0.0041031186,0.0026188844,0.00014480007,0.00002988546,0.00003473946,0.00042051953,0.00015156594,0.0015644683],"genre_scores_gemma":[0.9917557,0.0013465678,0.0025734464,0.000060500046,0.000016870546,0.00007976629,0.0006939669,0.00003112096,0.0034420951],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998914,0.000015273858,0.000014344959,0.00002411662,0.000028433482,0.000026361757],"domain_scores_gemma":[0.99985766,0.000021311716,0.000039216713,0.00002044924,0.000026958654,0.000034451685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010340123,0.00036220677,0.0002480276,0.0003228336,0.00028149356,0.0004491692,0.000323418,0.0002712891,0.0007885818],"category_scores_gemma":[0.00012528732,0.00020833274,0.000276965,0.00016900594,0.00025130415,0.00031482853,0.0003308907,0.00042263622,0.00039027317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009492849,0.000011162478,0.00029743044,0.000021766877,0.00000221493,0.000036156187,0.00001647932,0.000035782396,0.99850166,0.00012969952,0.000028232118,0.00082445063],"study_design_scores_gemma":[0.000027481114,0.00013206316,0.015675457,0.0000071182385,0.000013462415,0.00017818165,0.00003211128,0.001254085,0.9794038,0.0000923404,0.0031784272,0.0000055484606],"about_ca_topic_score_codex":0.0014269421,"about_ca_topic_score_gemma":0.0026443074,"teacher_disagreement_score":0.0014269421,"about_ca_system_score_codex":0.00055917585,"about_ca_system_score_gemma":0.00024879616,"threshold_uncertainty_score":0.004057169},"labels":[],"label_agreement":null},{"id":"W2152418942","doi":"10.25011/cim.v34i6.15896","title":"Over-expression of extracellular matrix metalloproteinase inducer in prostate cancer is associated with high risk of prostate-specific antigen relapse after radical prostatectomy","year":2011,"lang":"en","type":"article","venue":"Clinical and investigative medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Prostatectomy; Medicine; Prostate cancer; Prostate-specific antigen; Immunohistochemistry; Pathological; Oncology; Proportional hazards model; Internal medicine; Prostate; Grading (engineering); Cancer; Urology; Biology","score_opus":0.05541814170856611,"score_gpt":0.2968484956320586,"score_spread":0.2414303539234925,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2152418942","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99863774,0.0009796328,0.00013348485,0.000024142702,0.000004621565,0.0000035281173,0.000052079205,0.000010952464,0.00015386518],"genre_scores_gemma":[0.999608,0.00014275797,0.000056596513,0.000007882351,0.000010032612,0.0000021305204,0.00007580221,0.0000012920856,0.00009555477],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9999018,0.000020176934,0.000007838888,0.000022343313,0.00003344661,0.000014320052],"domain_scores_gemma":[0.99954104,0.00008241491,0.00020376616,0.00002390236,0.00003934295,0.000109559594],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016846246,0.0001633114,0.00020780819,0.00038391654,0.00016085764,0.0002507544,0.00016165427,0.00020086065,0.001045725],"category_scores_gemma":[0.0005896276,0.000113538525,0.00016735613,0.00038506475,0.00021710181,0.00011728315,0.00016154072,0.00034774156,0.00012963887],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005311716,0.00006868439,0.978079,0.0000634723,0.000085748296,0.00028716537,0.000058623787,0.00007367607,0.01537128,0.000022770168,0.0001787465,0.0051795715],"study_design_scores_gemma":[0.0000052946975,0.000080604055,0.9979479,0.0000019767695,0.000033328542,0.0009396727,0.00002473172,0.0001413972,0.0006575076,0.000018033923,0.00014724341,0.0000021973146],"about_ca_topic_score_codex":0.0004529797,"about_ca_topic_score_gemma":0.00061276654,"teacher_disagreement_score":0.001045725,"about_ca_system_score_codex":0.000113455404,"about_ca_system_score_gemma":0.00014791178,"threshold_uncertainty_score":0.0034983158},"labels":[],"label_agreement":null},{"id":"W2155129332","doi":"10.1242/jcs.02408","title":"Basigin (EMMPRIN/CD147) interacts with integrin to affect cellular architecture","year":2005,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Institute of General Medical Sciences; National Eye Institute","keywords":"Basigin; Biology; Cell biology; Integrin; Cytoskeleton; Extracellular matrix; Cell; Cell adhesion; Matrix metalloproteinase; Biochemistry","score_opus":0.005784763013941747,"score_gpt":0.2439626278225725,"score_spread":0.23817786480863076,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2155129332","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945598,0.0010787759,0.0015635529,0.000100913545,0.000021693666,0.000012866243,0.00013609663,0.000047962534,0.0024783334],"genre_scores_gemma":[0.9947784,0.0005397064,0.0010376667,0.000042611817,0.0000042760385,0.0000133752355,0.00017145774,0.000012953106,0.0033996666],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991155,0.000013281883,0.0000044209546,0.000015123306,0.000028175244,0.000027464566],"domain_scores_gemma":[0.9999608,0.000006477801,0.000011908547,0.000004031309,0.0000034795303,0.000013317774],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007080065,0.00035419822,0.00011507836,0.00014050183,0.00015008163,0.00018645373,0.00022656567,0.00037484278,0.0012160786],"category_scores_gemma":[0.000070629234,0.00014740771,0.00013540273,0.000069580936,0.00018919643,0.000128182,0.00019765712,0.00032125824,0.00037053722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034265253,0.000008798401,0.00011436708,0.000010304763,0.0000023209866,0.00007586501,0.0000031095576,0.000026155563,0.9991442,0.000073118106,0.000031459494,0.0004760666],"study_design_scores_gemma":[0.000014666224,0.00010495137,0.004594784,0.0000024834821,0.000011070637,0.0004902386,0.000009473553,0.0005734061,0.9916585,0.000033280347,0.002505015,0.0000020590242],"about_ca_topic_score_codex":0.000705171,"about_ca_topic_score_gemma":0.0011545076,"teacher_disagreement_score":0.0012160786,"about_ca_system_score_codex":0.0005753499,"about_ca_system_score_gemma":0.000096114694,"threshold_uncertainty_score":0.004174471},"labels":[],"label_agreement":null},{"id":"W2156858954","doi":"10.1016/j.ijcard.2015.06.024","title":"Matrix metalloproteinases and their tissue inhibitor after reperfused ST-elevation myocardial infarction treated with doxycycline. Insights from the TIPTOP trial","year":2015,"lang":"en","type":"article","venue":"International Journal of Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Doxycycline; Myocardial infarction; Percutaneous coronary intervention; Cardiology; Internal medicine; Matrix metalloproteinase; Ventricular remodeling","score_opus":0.014532040042620209,"score_gpt":0.264162416810196,"score_spread":0.24963037676757577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156858954","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9730762,0.021904875,0.00032038998,0.00081011176,0.00031393341,0.0001920631,0.00060606963,0.00003602157,0.002740221],"genre_scores_gemma":[0.98514545,0.010364721,0.00039321365,0.0006734712,0.00033964487,0.00028153657,0.0010021866,0.000008998737,0.0017908256],"study_design_codex":"randomized_trial","study_design_gemma":"observational","domain_scores_codex":[0.9998209,0.00006387505,0.000016228187,0.00002027276,0.000026271107,0.000052531865],"domain_scores_gemma":[0.99975866,0.000064087435,0.000055271907,0.0000190665,0.00001654663,0.00008626869],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057480065,0.0004850855,0.0011968954,0.00011850953,0.00013607305,0.0006132413,0.00025537334,0.00053272187,0.0013711224],"category_scores_gemma":[0.000742024,0.00010649759,0.0005266919,0.00023764344,0.00023989765,0.00040815497,0.00019716886,0.0014095374,0.00024025106],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.7567483,0.003280453,0.008921126,0.0019459567,0.0020604418,0.0005025734,0.00011519504,0.0008570466,0.019274028,0.0007912107,0.0058477246,0.19965596],"study_design_scores_gemma":[0.6613874,0.17991956,0.12581317,0.00071499,0.0046783034,0.0010073672,0.00025661552,0.0021511782,0.0082236165,0.0013533763,0.014426714,0.00006767372],"about_ca_topic_score_codex":0.0003305672,"about_ca_topic_score_gemma":0.0010160403,"teacher_disagreement_score":0.0013711224,"about_ca_system_score_codex":0.00026405172,"about_ca_system_score_gemma":0.0002460742,"threshold_uncertainty_score":0.004586816},"labels":[],"label_agreement":null},{"id":"W2157061673","doi":"10.1016/j.ydbio.2010.05.317","title":"Agtrl1b acts non-cell-autonomously for proper cell migration during myocardial progenitor development","year":2010,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Biology; Progenitor cell; Progenitor; Cell biology; Cell; Cell migration; Stem cell; Genetics","score_opus":0.006980366757152122,"score_gpt":0.22321571754661892,"score_spread":0.2162353507894668,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157061673","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96822315,0.005894885,0.014279799,0.00080113026,0.00023575671,0.000048073158,0.0013367066,0.000874037,0.008306377],"genre_scores_gemma":[0.9824785,0.00081445073,0.007233751,0.000250123,0.000034413784,0.00007526144,0.001674564,0.00029698934,0.0071419515],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99949443,0.0000658112,0.00003855147,0.00011971145,0.00013158568,0.000149929],"domain_scores_gemma":[0.9996836,0.00003723828,0.00009868728,0.000047974212,0.000038061455,0.00009453193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032132748,0.00049346505,0.00037748442,0.0005242459,0.00042334967,0.0008018341,0.00062120805,0.00065232394,0.0020794976],"category_scores_gemma":[0.0003104604,0.00044878165,0.00040714495,0.0002095172,0.00041594656,0.0004600686,0.00051155355,0.0016403346,0.0029656684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008015939,0.000009187388,0.00013980926,0.00001716209,0.0000024856186,0.00005503923,0.000006575135,0.000025143345,0.9985556,0.00015416979,0.00010170273,0.0008530588],"study_design_scores_gemma":[0.000025064961,0.000051475054,0.0041702907,0.0000073571264,0.000009986672,0.00038575046,0.00003011334,0.00083402114,0.99043334,0.0000824053,0.0039638286,0.000006328566],"about_ca_topic_score_codex":0.000618177,"about_ca_topic_score_gemma":0.0014682267,"teacher_disagreement_score":0.0020794976,"about_ca_system_score_codex":0.0007010297,"about_ca_system_score_gemma":0.00038197133,"threshold_uncertainty_score":0.0069565773},"labels":[],"label_agreement":null},{"id":"W2157891350","doi":"10.1093/carcin/bgt345","title":"Prodomain of the proprotein convertase subtilisin/kexin Furin (ppFurin) protects from tumor progression and metastasis","year":2013,"lang":"en","type":"article","venue":"Carcinogenesis","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Clinical Research Institute","funders":"Institut National Du Cancer","keywords":"Furin; Proprotein convertase; Kexin; Metastasis; Cancer research; Growth factor; Pancreatic cancer; Tumor progression; Biology; Endocrinology; Internal medicine; Cancer; Medicine; Receptor; LDL receptor; Lipoprotein; Biochemistry","score_opus":0.007286794040059441,"score_gpt":0.21033375852470063,"score_spread":0.20304696448464118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2157891350","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99655735,0.0010093665,0.0016130476,0.000056489207,0.000023966231,0.00001775787,0.00015493765,0.000051353334,0.00051565026],"genre_scores_gemma":[0.99589854,0.00066235213,0.0009353873,0.000025644049,0.000010258817,0.00002151847,0.00045765366,0.000011254639,0.0019773927],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990845,0.000015375559,0.0000089465975,0.000015959322,0.000025835012,0.000025344645],"domain_scores_gemma":[0.99987054,0.000020329413,0.00004133932,0.000018549443,0.0000114895465,0.00003777934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011530055,0.000386558,0.0002533928,0.00017096911,0.00010392168,0.00023173678,0.00016239849,0.00025413168,0.0010181905],"category_scores_gemma":[0.00010353375,0.0001295893,0.00022116446,0.00009550886,0.00014648854,0.00014491557,0.00010577023,0.00067203026,0.00025203984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014720374,0.000062064195,0.00007555665,0.000011536675,0.0000035365758,0.000034680186,0.00000500209,0.000029850948,0.9987986,0.000036994894,0.000016921014,0.00077804975],"study_design_scores_gemma":[0.000023565459,0.001488237,0.002456609,0.0000035090047,0.000011460302,0.00031971405,0.000012121322,0.00038337632,0.9941718,0.000031795153,0.0010948703,0.000002881761],"about_ca_topic_score_codex":0.00029588232,"about_ca_topic_score_gemma":0.00032322473,"teacher_disagreement_score":0.0010181905,"about_ca_system_score_codex":0.00012917194,"about_ca_system_score_gemma":0.00017749431,"threshold_uncertainty_score":0.0034062266},"labels":[],"label_agreement":null},{"id":"W2158035115","doi":"10.2337/db08-0178","title":"Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in β-Cells","year":2009,"lang":"en","type":"article","venue":"Diabetes","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":206,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Medical Research Council; Novo Nordisk; Sundhed og Sygdom, Det Frie Forskningsråd","keywords":"Proinflammatory cytokine; Cell biology; Apoptosis; Dephosphorylation; Biology; Programmed cell death; DNA fragmentation; Cytochrome c; Cytokine; Intrinsic apoptosis; Caspase; Tumor necrosis factor alpha; Mitochondrion; Chemistry; Immunology; Phosphorylation; Inflammation; Biochemistry; Phosphatase","score_opus":0.006770908525696374,"score_gpt":0.21231292871237764,"score_spread":0.20554202018668127,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158035115","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9589682,0.030450879,0.006540994,0.00038013415,0.00013961608,0.000074549724,0.0004947229,0.00009891787,0.0028519528],"genre_scores_gemma":[0.98360115,0.012494969,0.0017811809,0.00012937085,0.00007820702,0.000052094376,0.00034308364,0.000010362333,0.0015095357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979967,0.000045501565,0.000020175741,0.000030045085,0.000054533968,0.000050120456],"domain_scores_gemma":[0.9997614,0.000031079537,0.00010240703,0.000019334364,0.000053921554,0.000031990327],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020896038,0.0007413088,0.00024604346,0.00022870436,0.00020261762,0.00052754453,0.00011979409,0.0002169729,0.0019600908],"category_scores_gemma":[0.00022671693,0.00011474207,0.00028868185,0.0001641097,0.00020392062,0.00033355338,0.00026043065,0.00058141217,0.00047715794],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076138467,0.00006267795,0.001871941,0.00030209965,0.000025109981,0.0002510135,0.00004148675,0.00008385901,0.991779,0.00024407542,0.00010259973,0.0044747503],"study_design_scores_gemma":[0.00014264934,0.001189464,0.02455839,0.00009693398,0.000080035206,0.002440787,0.00011741504,0.0008562532,0.9630678,0.0005793215,0.0068614674,0.00000934707],"about_ca_topic_score_codex":0.00007290549,"about_ca_topic_score_gemma":0.000109110726,"teacher_disagreement_score":0.0019600908,"about_ca_system_score_codex":0.00024982015,"about_ca_system_score_gemma":0.00021100433,"threshold_uncertainty_score":0.0065571666},"labels":[],"label_agreement":null},{"id":"W2158542348","doi":"","title":"FKBP12.6 mice display temporal gender differences in cardiac Ca2+-signalling phenotype upon chronic pressure overload","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"NFAT; Calcineurin; Pressure overload; Ryanodine receptor 2; Internal medicine; Ryanodine receptor; Endocrinology; FKBP; Muscle hypertrophy; Heart failure; Hypertrophic cardiomyopathy; Left ventricular hypertrophy; Medicine; Receptor; Chemistry; Biology; Cell biology; Blood pressure; Transplantation; Cardiac hypertrophy","score_opus":0.02454345613844767,"score_gpt":0.2533673426367259,"score_spread":0.22882388649827823,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158542348","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9858139,0.0015337963,0.0050243353,0.0006464351,0.00025423997,0.00006072924,0.0042263656,0.0003169298,0.0021233682],"genre_scores_gemma":[0.9634548,0.001757745,0.003912891,0.00049759616,0.00010267792,0.00032359382,0.002870072,0.00033882243,0.02674181],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995159,0.0000413547,0.000054279637,0.00016199297,0.00009879482,0.00012767673],"domain_scores_gemma":[0.9993667,0.00004097209,0.0002505215,0.00004138403,0.000042748714,0.0002576772],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038486897,0.00088529993,0.0007751269,0.001041434,0.00045525518,0.0006042223,0.00051067735,0.0010316593,0.0077408617],"category_scores_gemma":[0.0002665071,0.00059152255,0.0006439498,0.00031253358,0.00079473417,0.0006082176,0.0004927788,0.0018473899,0.0018583686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00088167895,0.0001303967,0.0005283751,0.000058080066,0.000011575948,0.00034233223,0.000077120865,0.000034599103,0.99565303,0.00018692078,0.00019445308,0.0019013252],"study_design_scores_gemma":[0.0006484163,0.002882081,0.10382228,0.00014388768,0.0002851915,0.007890873,0.00062590366,0.0013854955,0.86652637,0.0010629803,0.014587934,0.00013847684],"about_ca_topic_score_codex":0.0008508028,"about_ca_topic_score_gemma":0.0016415556,"teacher_disagreement_score":0.0077408617,"about_ca_system_score_codex":0.00037051938,"about_ca_system_score_gemma":0.0002735586,"threshold_uncertainty_score":0.025895715},"labels":[],"label_agreement":null},{"id":"W2158577141","doi":"10.4049/jimmunol.1203196","title":"Regulator of Calcineurin 1 Suppresses Inflammation during Respiratory Tract Infections","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Izaak Walton Killam Health Centre; Dalhousie University","funders":"","keywords":"Regulator; Calcineurin; Inflammation; Respiratory tract; Negative regulator; Immunology; Respiratory system; Respiratory tract infections; Medicine; Biology; Microbiology; Internal medicine; Cell biology; Signal transduction; Transplantation; Biochemistry","score_opus":0.009558116714858,"score_gpt":0.2379580763564125,"score_spread":0.2283999596415545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2158577141","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9933255,0.0032684295,0.0018118675,0.00016972453,0.000050490627,0.000021512096,0.00013928565,0.000115769675,0.0010975581],"genre_scores_gemma":[0.99636984,0.00085365464,0.0011397845,0.00005985768,0.000019504872,0.000020557796,0.00017871668,0.000018193115,0.0013399483],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998184,0.000041456864,0.00001296161,0.000027809103,0.000058259066,0.000041062638],"domain_scores_gemma":[0.99978036,0.000034445144,0.00007335932,0.00002500516,0.00002581668,0.00006096108],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002436388,0.00038808072,0.00027598577,0.00029645866,0.0001452203,0.0003016571,0.00029680057,0.00026475784,0.0007471531],"category_scores_gemma":[0.00020855074,0.00010012643,0.00015485902,0.00011122028,0.0003655956,0.00018063326,0.00017545038,0.0007320501,0.00020491348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015360232,0.000036502366,0.0002234142,0.000025788137,0.0000030913181,0.000041398318,0.000008732833,0.000059342157,0.9979723,0.00006691938,0.000032757074,0.0013760561],"study_design_scores_gemma":[0.000029906332,0.00058750564,0.0057450775,0.000008566379,0.000019281266,0.00035671555,0.00002267981,0.0009299156,0.9900025,0.00009126454,0.0022016012,0.000005039551],"about_ca_topic_score_codex":0.00024327992,"about_ca_topic_score_gemma":0.0006122587,"teacher_disagreement_score":0.0007471531,"about_ca_system_score_codex":0.00025459076,"about_ca_system_score_gemma":0.00025369375,"threshold_uncertainty_score":0.0024994612},"labels":[],"label_agreement":null},{"id":"W2159559614","doi":"10.1039/c4cp01342e","title":"Computational investigations on the catalytic mechanism of maleate isomerase: the role of the active site cysteine residues","year":2014,"lang":"en","type":"article","venue":"Physical Chemistry Chemical Physics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; Compute Canada","keywords":"Active site; Cysteine; Chemistry; Mechanism (biology); Isomerase; Catalysis; Substrate (aquarium); Stereochemistry; Combinatorial chemistry; Biochemistry; Enzyme; Biology; Physics","score_opus":0.007991073639827241,"score_gpt":0.21997966683783515,"score_spread":0.21198859319800792,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159559614","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9659336,0.0007854178,0.020683406,0.0005623565,0.000049617876,0.0000643324,0.0011665339,0.00022030684,0.010534366],"genre_scores_gemma":[0.9877774,0.00063329283,0.009329109,0.00011657678,0.00001797408,0.00014280358,0.0009566395,0.000061387596,0.00096478953],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.99991214,0.000026847818,0.0000039657907,0.00001437137,0.000021604925,0.000021079184],"domain_scores_gemma":[0.9996069,0.0002660234,0.000023829914,0.000025387917,0.000049834285,0.000028071836],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003568667,0.00084359077,0.0010498196,0.00046714768,0.00057040865,0.0006008951,0.0015172361,0.0011813017,0.002305564],"category_scores_gemma":[0.0010506825,0.00028201606,0.0006716259,0.000650637,0.0004748194,0.00052451785,0.0004638563,0.00081901654,0.00025465802],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016868327,0.00009316739,0.0022886926,0.0003278848,0.00008858974,0.00029336457,0.00006273907,0.98292404,0.0035196885,0.005126174,0.00042979317,0.0046771998],"study_design_scores_gemma":[0.00004361525,0.000070577,0.00063465664,0.000013715329,0.00002922108,0.000024663284,0.000035862355,0.9962993,0.0012772797,0.0011485857,0.00041494693,0.0000075910575],"about_ca_topic_score_codex":0.008665399,"about_ca_topic_score_gemma":0.0061275824,"teacher_disagreement_score":0.008665399,"about_ca_system_score_codex":0.00072919397,"about_ca_system_score_gemma":0.0013277903,"threshold_uncertainty_score":0.017229974},"labels":[],"label_agreement":null},{"id":"W2160880695","doi":"10.1128/mcb.22.20.6993-7003.2002","title":"Cyclophilin A Peptidyl-Prolyl Isomerase Activity Promotes Zpr1 Nuclear Export","year":2002,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Columbia College","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Biology; Prolyl isomerase; Cyclophilin; Peptidylprolyl isomerase; Cis-trans-Isomerases; Cyclophilin A; Isomerase; Mutant; Saccharomyces cerevisiae; Nuclear transport; Cytoplasm; Complementation; Mutation; Nuclear localization sequence; PIN1; Biochemistry; Gene; Cell biology; Molecular biology; Cell nucleus","score_opus":0.011292334899733377,"score_gpt":0.21860038739683926,"score_spread":0.20730805249710588,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160880695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960705,0.0008692454,0.0013362902,0.00009109823,0.000007775234,0.000006701316,0.0004189683,0.00009544426,0.0011040871],"genre_scores_gemma":[0.99551105,0.000499123,0.0012599514,0.00003687738,0.0000062856207,0.000008131957,0.00094602385,0.000026601989,0.0017059981],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999087,0.0000127005105,0.000007265049,0.00002602662,0.000025871903,0.000019393428],"domain_scores_gemma":[0.99983346,0.000027124877,0.000052881416,0.000024242807,0.000016413096,0.00004574511],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007888398,0.00030686826,0.00015989928,0.00017553456,0.00011160572,0.0003409308,0.00016519439,0.00014989913,0.0013982242],"category_scores_gemma":[0.000115878785,0.00014217269,0.00016922638,0.00010779064,0.0001551928,0.00013729976,0.00023554669,0.00036340952,0.0007386401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028227509,0.0000041403546,0.00018477331,0.000011749259,0.000001692814,0.000036660087,0.000003866503,0.000016857904,0.9993284,0.000027295997,0.000018646979,0.00033781034],"study_design_scores_gemma":[0.000010189033,0.00007801292,0.01318244,0.0000070925944,0.000008002774,0.00051101,0.00003260192,0.0009803127,0.9835217,0.00003385553,0.0016318202,0.0000030324509],"about_ca_topic_score_codex":0.0005739748,"about_ca_topic_score_gemma":0.00085372914,"teacher_disagreement_score":0.0013982242,"about_ca_system_score_codex":0.00026689665,"about_ca_system_score_gemma":0.00014625434,"threshold_uncertainty_score":0.0046775937},"labels":[],"label_agreement":null},{"id":"W2160980614","doi":"10.1139/y2012-038","title":"Cyclophilin-A: a potential screening marker for vascular disease in type-2 diabetes","year":2012,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Indian Council of Medical Research","keywords":"Type 2 diabetes; Diabetes mellitus; Endothelial dysfunction; Insulin resistance; Internal medicine; Oxidative stress; Vascular disease; Pathogenesis; Vascular smooth muscle; Endocrinology; Cyclophilin A; Biology; Disease; Medicine; Immunology","score_opus":0.025084990290498634,"score_gpt":0.3007361319108096,"score_spread":0.27565114162031096,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2160980614","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025910704,0.99857247,0.00016186107,0.00022803506,0.00013711107,0.0000039618517,0.000020936583,0.0000060024768,0.0006105818],"genre_scores_gemma":[0.0021066118,0.99656904,0.00033123995,0.000162086,0.00016877905,0.0000078516905,0.000047142013,0.000001325663,0.00060588086],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998597,0.000025245714,0.000019917972,0.000028328215,0.00005522528,0.000011660276],"domain_scores_gemma":[0.9997584,0.00011543891,0.000031295196,0.000005381625,0.00006373677,0.000025665095],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000424288,0.0006347631,0.001152979,0.0022280652,0.00017302978,0.00050528796,0.0005221616,0.00090862345,0.0018062226],"category_scores_gemma":[0.00045221302,0.00018943129,0.00035913184,0.0012970323,0.0002930821,0.00057798787,0.00029651774,0.0011161875,0.0011746946],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012005411,0.000077161174,0.00090030715,0.008038689,0.00012337297,0.00042620618,0.00003806925,0.00016628932,0.0036325918,0.0016079746,0.014729778,0.9701395],"study_design_scores_gemma":[0.000048217782,0.00032586994,0.007606495,0.003197498,0.00038576376,0.006709621,0.00011213088,0.00024531677,0.0034553946,0.002266584,0.9755973,0.000049791095],"about_ca_topic_score_codex":0.0010809622,"about_ca_topic_score_gemma":0.0017031927,"teacher_disagreement_score":0.0022280652,"about_ca_system_score_codex":0.00039028935,"about_ca_system_score_gemma":0.0005737006,"threshold_uncertainty_score":0.006042421},"labels":[],"label_agreement":null},{"id":"W2161980994","doi":"10.1016/j.pneurobio.2007.09.004","title":"Myristoyltransferase and calcineurin: Novel molecular therapeutic target for epilepsy","year":2007,"lang":"en","type":"review","venue":"Progress in Neurobiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency; University of Saskatchewan","funders":"","keywords":"Myristoylation; Kinase; Signal transduction; Biology; Calcineurin; Cell biology; Cyclin-dependent kinase 5; Protein kinase A; Phosphorylation; Prenylation; Biochemistry; Neuroscience; Enzyme; Cyclin-dependent kinase 2; Medicine","score_opus":0.05334884809553481,"score_gpt":0.3662994699380972,"score_spread":0.3129506218425624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2161980994","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00030201545,0.9960328,0.0004764157,0.00083671947,0.0005792441,0.0000066866346,0.00001884699,0.000022367505,0.0017249814],"genre_scores_gemma":[0.0013871073,0.99452543,0.00072861114,0.00063421513,0.0005751933,0.000014274277,0.000052363535,0.000003287611,0.0020795816],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998771,0.00001443402,0.000014258133,0.000021410851,0.000056319506,0.000016363032],"domain_scores_gemma":[0.99984527,0.00005594882,0.00002349143,0.0000059940144,0.000043041695,0.000026210908],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00057778275,0.0011180269,0.0014264482,0.0012095281,0.00026712855,0.0008536897,0.0010063469,0.0014878801,0.0028839922],"category_scores_gemma":[0.0004065795,0.00022665663,0.00031187935,0.0014305769,0.00061804446,0.0013061402,0.00061323546,0.0023255243,0.0027302876],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022760962,0.00010358059,0.000155531,0.0038774754,0.000064553635,0.0006224792,0.000033494292,0.00041051806,0.006341487,0.004946525,0.06270622,0.92051065],"study_design_scores_gemma":[0.000074053336,0.000086757806,0.00048252824,0.00057922356,0.0000662183,0.0021544413,0.00003628934,0.00013454801,0.0012723338,0.002219959,0.99287885,0.000014698409],"about_ca_topic_score_codex":0.00062867976,"about_ca_topic_score_gemma":0.0017182196,"teacher_disagreement_score":0.0028839922,"about_ca_system_score_codex":0.0006540892,"about_ca_system_score_gemma":0.00081767683,"threshold_uncertainty_score":0.009647965},"labels":[],"label_agreement":null},{"id":"W2163357887","doi":"10.1158/0008-5472.can-08-2110","title":"ADP-Ribosylation Factor 6 Regulates Glioma Cell Invasion through the IQ-Domain GTPase-Activating Protein 1-Rac1–Mediated Pathway","year":2009,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Immunovaccine (Canada)","funders":"National Cancer Institute; National Institutes of Health","keywords":"IQGAP1; RAC1; Glioma; Cell migration; Small interfering RNA; Cancer research; Small GTPase; Biology; ADP ribosylation factor; Gene knockdown; Cell biology; GTPase-activating protein; Scaffold protein; Signal transduction; Cell; Chemistry; Transfection; Cell culture; G protein; Biochemistry","score_opus":0.059963167735313905,"score_gpt":0.34951963870754127,"score_spread":0.28955647097222736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163357887","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99248135,0.0022855059,0.0020777404,0.00019710606,0.00001961964,0.00000904207,0.00010421299,0.00009418962,0.0027313111],"genre_scores_gemma":[0.9962967,0.0010621215,0.0010785168,0.000030123862,0.000008883511,0.000008170709,0.00017627967,0.000010485237,0.0013286906],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991965,0.000020434403,0.0000036020328,0.000009991611,0.00002297011,0.000023286335],"domain_scores_gemma":[0.99994004,0.000007880985,0.000017364671,0.000004470649,0.000010827369,0.000019395926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008268587,0.00033121958,0.0001188623,0.0002588217,0.0001960424,0.0002566071,0.00012597736,0.00015726956,0.00079064013],"category_scores_gemma":[0.00009477616,0.00008493787,0.00016895213,0.000087689274,0.00020919602,0.00016079156,0.00015112996,0.00033923742,0.00043796352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010386753,0.000023115565,0.0002644692,0.000025511381,0.0000022132892,0.00009208044,0.000019544854,0.000098887045,0.9975879,0.00022152827,0.00008487581,0.0014759414],"study_design_scores_gemma":[0.000028982973,0.00025110328,0.01790443,0.000009215791,0.00001858487,0.00077256124,0.000078805,0.005047456,0.9686742,0.00041287876,0.006792393,0.000009425956],"about_ca_topic_score_codex":0.00046674238,"about_ca_topic_score_gemma":0.0006867576,"teacher_disagreement_score":0.00079064013,"about_ca_system_score_codex":0.00025128163,"about_ca_system_score_gemma":0.00012808072,"threshold_uncertainty_score":0.0026448965},"labels":[],"label_agreement":null},{"id":"W2163382569","doi":"10.1101/gad.887201","title":"Regulation of translation initiation by FRAP/mTOR","year":2001,"lang":"en","type":"review","venue":"Genes & Development","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1536,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Cancer Institute; Medical Research Council; Canadian Institutes of Health Research; Medical Research Council Canada; Howard Hughes Medical Institute","keywords":"Biology; Translation (biology); Eukaryotic translation; PI3K/AKT/mTOR pathway; Cell biology; Computational biology; eIF2; Genetics; Signal transduction; Messenger RNA; Gene","score_opus":0.047829050605386295,"score_gpt":0.3055993278234277,"score_spread":0.2577702772180414,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163382569","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0012473918,0.99180025,0.0015530854,0.00048389815,0.00065162923,0.000016692535,0.00007268422,0.00008569631,0.0040885895],"genre_scores_gemma":[0.008607789,0.986211,0.0014833467,0.0002781222,0.0005338222,0.00003747263,0.0001636898,0.000013300786,0.0026714543],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99977654,0.000028239898,0.000029881057,0.00006138496,0.0000634898,0.00004035411],"domain_scores_gemma":[0.9998276,0.00006547742,0.000039851788,0.000011268662,0.000039967952,0.000015837335],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005860986,0.0015848774,0.0017251931,0.0017202491,0.00051319995,0.0017304881,0.0013129665,0.0012782144,0.0021671134],"category_scores_gemma":[0.00038323243,0.0005166745,0.00046267215,0.0015862286,0.0008838418,0.0011595279,0.00064493,0.0019316983,0.003289127],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005103612,0.00010638804,0.00032357633,0.009662775,0.00012854087,0.0016256272,0.0001175389,0.0016046477,0.07313108,0.0151470015,0.030902022,0.86674047],"study_design_scores_gemma":[0.00009879135,0.00019713373,0.0026203783,0.0012070879,0.00018228324,0.003893138,0.00012611144,0.0007173679,0.055316452,0.0065118005,0.92906153,0.000067872345],"about_ca_topic_score_codex":0.0006723878,"about_ca_topic_score_gemma":0.00101071,"teacher_disagreement_score":0.0021671134,"about_ca_system_score_codex":0.0010630895,"about_ca_system_score_gemma":0.0006374205,"threshold_uncertainty_score":0.007713318},"labels":[],"label_agreement":null},{"id":"W2163785860","doi":"10.1074/jbc.m201747200","title":"Expression of Endomembrane Calcium Pumps in Colon and Gastric Cancer Cells","year":2002,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Sherbrooke","funders":"","keywords":"SERCA; Calcium pump; Calcium ATPase; Calcium; Butyrate; Endoplasmic reticulum; Cell biology; Calcium in biology; Cancer cell; Chemistry; Cancer research; Biology; ATPase; Internal medicine; Cancer; Biochemistry; Enzyme; Medicine","score_opus":0.030317300269326167,"score_gpt":0.2642995586013503,"score_spread":0.23398225833202413,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2163785860","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9919098,0.002887993,0.0015648662,0.0001256883,0.000030420371,0.000046355057,0.0013602161,0.000054505494,0.002020176],"genre_scores_gemma":[0.9896045,0.0020777634,0.0024556408,0.000080852384,0.000009184822,0.000078068224,0.0019924513,0.000013405935,0.003688208],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998863,0.000009770698,0.000010863949,0.00002345711,0.00004035284,0.000029182826],"domain_scores_gemma":[0.9999299,0.000007967038,0.000014456632,0.00001279451,0.00001657823,0.000018314115],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008112421,0.00013567685,0.00016463883,0.00027402616,0.00016358211,0.00021309347,0.000086858956,0.00022264804,0.0010995017],"category_scores_gemma":[0.00008144652,0.00011604366,0.00021798191,0.00047256265,0.00013531212,0.00012689678,0.00013932819,0.00032914203,0.00040834976],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014406888,0.0000076728165,0.00053038105,0.00002822926,0.0000030984845,0.00008947385,0.000022519554,0.0000159961,0.99829406,0.000047065038,0.00003265464,0.00078483747],"study_design_scores_gemma":[0.000059798607,0.0006679735,0.11357932,0.000014814425,0.000043310964,0.0022280407,0.00030319043,0.0012359384,0.8686263,0.00007989028,0.013144213,0.000017255288],"about_ca_topic_score_codex":0.0031841162,"about_ca_topic_score_gemma":0.0034347007,"teacher_disagreement_score":0.0031841162,"about_ca_system_score_codex":0.00024700267,"about_ca_system_score_gemma":0.00030954747,"threshold_uncertainty_score":0.0063311458},"labels":[],"label_agreement":null},{"id":"W2164316200","doi":"10.1186/1471-2121-5-22","title":"Multisite phosphorylation of Pin1-associated mitotic phosphoproteins revealed by monoclonal antibodies MPM-2 and CC-3","year":2004,"lang":"en","type":"article","venue":"BMC Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biology; PIN1; Molecular biology; Peptidylprolyl isomerase; Mitosis; Phosphorylation; Epitope; Prolyl isomerase; Cell biology; Biochemistry; Antigen; Isomerase; Genetics; Enzyme","score_opus":0.008692656027486636,"score_gpt":0.23256180211692867,"score_spread":0.22386914608944203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2164316200","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9786043,0.0025678654,0.014945166,0.00017285856,0.000045930643,0.000077475255,0.00042209568,0.00016970022,0.0029946142],"genre_scores_gemma":[0.97341746,0.0015744446,0.019801404,0.00029527638,0.000034279892,0.00020155002,0.0021978177,0.00006544894,0.002412352],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996878,0.000027531472,0.0000238388,0.00008068193,0.000076243356,0.00010393828],"domain_scores_gemma":[0.999759,0.00005351609,0.00006633827,0.000025678548,0.000040032042,0.0000553167],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027711238,0.00074669014,0.00019393631,0.0004598064,0.00021285264,0.00030503093,0.00048078733,0.0005417079,0.0019730362],"category_scores_gemma":[0.0002338293,0.00023953107,0.00046887482,0.00030931586,0.00022942905,0.00026747058,0.0003155867,0.0006931442,0.0005810263],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000047528003,0.0000069412927,0.00012366862,0.000029187115,0.0000052181404,0.000031765267,0.000005534762,0.00001839192,0.9993048,0.000042945216,0.000022843473,0.00036116695],"study_design_scores_gemma":[0.000019450941,0.00015767055,0.008457513,0.000013404553,0.000034898127,0.00090677344,0.000022047197,0.0011581904,0.98682886,0.00006436315,0.0023291688,0.000007626272],"about_ca_topic_score_codex":0.0004364093,"about_ca_topic_score_gemma":0.00062652223,"teacher_disagreement_score":0.0019730362,"about_ca_system_score_codex":0.000510625,"about_ca_system_score_gemma":0.00021944099,"threshold_uncertainty_score":0.0066004395},"labels":[],"label_agreement":null},{"id":"W2166133009","doi":"10.1242/dmm.014480","title":"Cyclosporin A enhances neural precursor cell survival in mice through a calcineurin-independent pathway","year":2014,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Calcineurin; In vivo; Cell biology; Pharmacology; Biology; Stem cell; Neural stem cell; Transplantation; Medicine; Internal medicine","score_opus":0.015609071765137827,"score_gpt":0.24057350901263613,"score_spread":0.22496443724749832,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2166133009","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9908784,0.0015017574,0.0028224897,0.00028293714,0.00008329116,0.000092624716,0.00058911456,0.00040605277,0.0033432734],"genre_scores_gemma":[0.9866687,0.0021179642,0.0040689465,0.00015812845,0.000056345238,0.00018009578,0.00069645693,0.00007508254,0.0059783007],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9996841,0.00005889103,0.000048688,0.00006725862,0.000075435346,0.000065624234],"domain_scores_gemma":[0.999603,0.000047597485,0.0001230377,0.000050714632,0.000028534356,0.00014713331],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026696638,0.00050204684,0.00041827123,0.0010498916,0.0002781951,0.00044313524,0.00041156492,0.00047855472,0.0015964115],"category_scores_gemma":[0.00017472934,0.00022411102,0.0003550297,0.000335259,0.0004280605,0.00033618577,0.00021833011,0.0011836817,0.00036296117],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044358522,0.00018961169,0.00024318823,0.000055909662,0.00001527037,0.000082462546,0.000026632782,0.00014775326,0.99571157,0.00023702523,0.00009486856,0.0027520936],"study_design_scores_gemma":[0.00013465119,0.0015957861,0.005184337,0.000023879857,0.000066191,0.0003014883,0.000034217734,0.0023542535,0.9859207,0.00013901944,0.00423254,0.000012827405],"about_ca_topic_score_codex":0.0008035581,"about_ca_topic_score_gemma":0.0016571828,"teacher_disagreement_score":0.0015964115,"about_ca_system_score_codex":0.00041885895,"about_ca_system_score_gemma":0.00042273002,"threshold_uncertainty_score":0.005340576},"labels":[],"label_agreement":null},{"id":"W2167462893","doi":"10.1016/j.yjmcc.2008.06.008","title":"Transient activation of P38 MAP kinase and up-regulation of Pim-1 kinase in cardiac hypertrophy despite no activation of AMPK","year":2008,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Heritage Medical Research Institute","keywords":"AMPK; Protein kinase B; p38 mitogen-activated protein kinases; Internal medicine; Phosphorylation; Kinase; Protein kinase A; Muscle hypertrophy; Endocrinology; Medicine; Pressure overload; AMP-activated protein kinase; Chemistry; Cell biology; Biology; Cardiac hypertrophy","score_opus":0.009143527966019695,"score_gpt":0.2065405549975598,"score_spread":0.1973970270315401,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167462893","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9906584,0.0021070829,0.0024804971,0.00073985214,0.00041428095,0.000083752435,0.00075268693,0.00017407945,0.0025893473],"genre_scores_gemma":[0.9917862,0.00058182975,0.0019728676,0.00021532834,0.0001285299,0.00024394244,0.0006952054,0.000039500366,0.004336556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995091,0.00007795892,0.000048559017,0.00007811863,0.0000834851,0.00020267801],"domain_scores_gemma":[0.9994406,0.00010059898,0.00009120965,0.00010288351,0.000030780247,0.00023392151],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005534276,0.0006649126,0.0006476988,0.00038255128,0.00045575164,0.00057750085,0.0005131493,0.0005243971,0.0033506209],"category_scores_gemma":[0.00044079596,0.0006523115,0.000670101,0.00032081996,0.0010145206,0.0007972711,0.00052087463,0.0022071179,0.0007315825],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0037645882,0.0002287945,0.00018666132,0.00009600825,0.000013710765,0.0002651538,0.000040188494,0.000064965716,0.9939628,0.00038627617,0.000178133,0.0008126615],"study_design_scores_gemma":[0.00037222737,0.0010026512,0.009580454,0.000011771898,0.000052012518,0.0005040056,0.00012432945,0.0010434563,0.985715,0.00023006018,0.0013477898,0.000016277521],"about_ca_topic_score_codex":0.00044796403,"about_ca_topic_score_gemma":0.00084735744,"teacher_disagreement_score":0.0033506209,"about_ca_system_score_codex":0.0006306127,"about_ca_system_score_gemma":0.0005252668,"threshold_uncertainty_score":0.0112089515},"labels":[],"label_agreement":null},{"id":"W2168109124","doi":"10.1083/jcb.200412156","title":"Calreticulin signals upstream of calcineurin and MEF2C in a critical Ca2+-dependent signaling cascade","year":2005,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research; University of Alberta","funders":"","keywords":"Calreticulin; MEF2C; Biology; Endoplasmic reticulum; Calcineurin; Cell biology; Enhancer; Signal transduction; Transcription factor; Mef2; Genetics; Transplantation; Internal medicine; Gene; Medicine","score_opus":0.016153417688649807,"score_gpt":0.2999147624558439,"score_spread":0.2837613447671941,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168109124","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9789684,0.005800734,0.00989476,0.0005864154,0.00008814012,0.0000484911,0.00023236628,0.00016963357,0.004211028],"genre_scores_gemma":[0.9883128,0.0016087728,0.006487947,0.00012340625,0.00002688133,0.000049313963,0.00024706486,0.00001928095,0.003124612],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997814,0.000043293272,0.000013892724,0.000043495726,0.00006367226,0.000054213033],"domain_scores_gemma":[0.999846,0.0000313301,0.000027804565,0.000016044696,0.000030889147,0.000047998798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022548642,0.00046989517,0.00032371812,0.0002572288,0.00029223834,0.00045168982,0.00022299924,0.00038605495,0.0008287655],"category_scores_gemma":[0.00021345768,0.00018555525,0.00020581146,0.000115103154,0.00033872246,0.00031535063,0.0005351884,0.0006735958,0.0003451018],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000067909554,0.00000787989,0.00010824681,0.000015982858,0.0000018611645,0.00012255728,0.000011146007,0.00006631917,0.99846125,0.0004569891,0.000024716848,0.000655035],"study_design_scores_gemma":[0.000047556707,0.00008737079,0.0049450803,0.000011220787,0.000011668296,0.00041443182,0.000027783768,0.0019670103,0.9860072,0.0005054965,0.005967648,0.0000075474823],"about_ca_topic_score_codex":0.00042507847,"about_ca_topic_score_gemma":0.0009980923,"teacher_disagreement_score":0.0008287655,"about_ca_system_score_codex":0.00065610954,"about_ca_system_score_gemma":0.00040704195,"threshold_uncertainty_score":0.004760444},"labels":[],"label_agreement":null},{"id":"W2168143869","doi":"10.1016/s1016-8478(23)13056-1","title":"Calreticulin, Ca2+, and Calcineurin - Signaling from the Endoplasmic Reticulum","year":2004,"lang":"en","type":"article","venue":"Molecules and Cells","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":123,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Institutes of Health Research","funders":"","keywords":"Endoplasmic reticulum; Calreticulin; Cell biology; STIM1; Calcium signaling; Calcineurin; Biology; Signal transduction; Cytoplasm; Internal medicine; Medicine; Transplantation","score_opus":0.005546225001623398,"score_gpt":0.19831437882940248,"score_spread":0.19276815382777907,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168143869","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.41458365,0.5181975,0.01891483,0.005659174,0.0012372854,0.00023406633,0.0015815527,0.0007709122,0.03882105],"genre_scores_gemma":[0.792999,0.15952979,0.0067113177,0.0009809358,0.00036643178,0.00014267433,0.0014085172,0.000057100027,0.03780429],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998267,0.000018269333,0.0000128245465,0.000045863748,0.000058911228,0.000037426118],"domain_scores_gemma":[0.9998826,0.00000695188,0.000040832172,0.000008123448,0.00002668412,0.000034757544],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018545885,0.0005380397,0.00039587644,0.00031019887,0.0004626201,0.0009049131,0.00038284206,0.0007639181,0.0011839089],"category_scores_gemma":[0.00012936731,0.00012975265,0.0002533196,0.0003453189,0.00038639002,0.00046001576,0.0005673049,0.0010276722,0.0006199622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00048475558,0.00011419102,0.0013642537,0.00094505993,0.00006177851,0.0014515226,0.00011087391,0.00055853557,0.9358799,0.010426558,0.003020122,0.04558248],"study_design_scores_gemma":[0.00019152887,0.0006362715,0.03885131,0.00025709666,0.00015671074,0.004277793,0.00034390672,0.0028426743,0.6565279,0.008956234,0.2868876,0.0000710068],"about_ca_topic_score_codex":0.0012981421,"about_ca_topic_score_gemma":0.0018977915,"teacher_disagreement_score":0.0012981421,"about_ca_system_score_codex":0.00084395777,"about_ca_system_score_gemma":0.0005076876,"threshold_uncertainty_score":0.006123364},"labels":[],"label_agreement":null},{"id":"W2168444218","doi":"10.1139/cjpp-79-8-646","title":"Mechanical load-induced alterations in B-type natriuretic peptide gene expression","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Internal medicine; Natriuretic peptide; Brain natriuretic peptide; Atrial natriuretic peptide; Volume overload; Autocrine signalling; NPR2; Endocrinology; Heart failure; Paracrine signalling; Angiotensin II; Gene expression; Medicine; Biology; Gene; Receptor","score_opus":0.019183617410113415,"score_gpt":0.2870657941201646,"score_spread":0.26788217671005116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2168444218","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9955016,0.0015983739,0.00078141567,0.00006662156,0.00006371172,0.00002525702,0.00042296766,0.00004056056,0.0014994154],"genre_scores_gemma":[0.9941514,0.0013818695,0.0005502537,0.00008421849,0.000031208037,0.00008277675,0.00052968005,0.000012033033,0.0031765937],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998542,0.000014734927,0.000007437327,0.000026170705,0.000044630942,0.000052951957],"domain_scores_gemma":[0.9998517,0.000041291496,0.000032863674,0.000014917654,0.000017966518,0.00004122673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010064094,0.00020298889,0.00023002458,0.0002828268,0.00014752486,0.00017243586,0.00012058316,0.00025462595,0.002442334],"category_scores_gemma":[0.00017145445,0.0001256157,0.00016191267,0.00021236693,0.00034908,0.00020665898,0.00018179456,0.00038771445,0.0002718196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026106904,0.00007319827,0.00040363907,0.000043645203,0.0000037194065,0.00010977908,0.0000376172,0.000029567216,0.9965044,0.000058583082,0.000055387747,0.0024193057],"study_design_scores_gemma":[0.000058114398,0.004779877,0.18426561,0.000021435399,0.000028897177,0.0008757987,0.00028341188,0.0008127313,0.8056392,0.00035449132,0.0028510487,0.000029360977],"about_ca_topic_score_codex":0.0005795717,"about_ca_topic_score_gemma":0.00077478826,"teacher_disagreement_score":0.002442334,"about_ca_system_score_codex":0.0002649803,"about_ca_system_score_gemma":0.00013488405,"threshold_uncertainty_score":0.008170426},"labels":[],"label_agreement":null},{"id":"W2169214205","doi":"10.1016/j.bbadis.2014.12.025","title":"Peroxide-mediated oxidation and inhibition of the peptidyl-prolyl isomerase Pin1","year":2015,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Western University","keywords":"PIN1; Chemistry; Sulfenic acid; Hydrogen peroxide; Sulfinic acid; Biochemistry; Cysteine; Oxidative phosphorylation; Isomerase; Prolyl isomerase; Neuroprotection; Peptidylprolyl isomerase; Enzyme; Pharmacology; Biology","score_opus":0.012552274096001558,"score_gpt":0.23864462602890454,"score_spread":0.22609235193290297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169214205","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946279,0.002255643,0.0018936775,0.000094265415,0.000040674495,0.00003467441,0.00022508577,0.00004618867,0.00078200514],"genre_scores_gemma":[0.9966888,0.0011522142,0.0009381713,0.000043620817,0.000008688087,0.000023046216,0.0002680647,0.0000084174035,0.00086901186],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990284,0.000013672673,0.000009325786,0.000022427512,0.000019029661,0.00003265939],"domain_scores_gemma":[0.9999305,0.000012304485,0.000028991379,0.0000069963708,0.000007934726,0.000013195046],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012705624,0.00042038882,0.00021864111,0.00009653465,0.000103262115,0.00014258825,0.00018207403,0.00019642373,0.00082364545],"category_scores_gemma":[0.00012344553,0.000105529056,0.00026917385,0.00008870033,0.00018904729,0.00014251309,0.00020221656,0.00041939053,0.00012696916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002185368,0.00002695348,0.00010678053,0.0000422358,0.000008396095,0.000043504548,0.00001157539,0.000050544186,0.9983015,0.000046729194,0.000033995693,0.0011091671],"study_design_scores_gemma":[0.000011588331,0.00028429265,0.0017420792,0.0000027119113,0.0000082408305,0.00010618804,0.000013302899,0.0002960871,0.99689496,0.000031253276,0.00060675107,0.0000025142388],"about_ca_topic_score_codex":0.0004357942,"about_ca_topic_score_gemma":0.00041424565,"teacher_disagreement_score":0.00082364545,"about_ca_system_score_codex":0.00016217596,"about_ca_system_score_gemma":0.00012752123,"threshold_uncertainty_score":0.002755344},"labels":[],"label_agreement":null},{"id":"W2169950117","doi":"10.1242/dev.081356","title":"<i>FKBP14</i>is an essential gene that regulates Presenilin protein levels and Notch signaling in<i>Drosophila</i>","year":2013,"lang":"en","type":"article","venue":"Development","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Notch signaling pathway; Presenilin; Notch proteins; Cell biology; Mutant; Hes3 signaling axis; Genetics; Cyclin-dependent kinase 8; Phenotype; Gene; Caenorhabditis elegans; Membrane protein; Signal transduction; Alzheimer's disease; Disease","score_opus":0.022330855451320075,"score_gpt":0.2401958550627969,"score_spread":0.21786499961147682,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2169950117","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98941934,0.0014522563,0.003985284,0.00010211305,0.0000436475,0.000029801333,0.002087738,0.0003021424,0.0025776413],"genre_scores_gemma":[0.983154,0.0006590509,0.0042337035,0.00012006239,0.000011975561,0.000046367964,0.0034321265,0.00010397829,0.008238919],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998981,0.0000066825633,0.000011362351,0.000028124288,0.000038259863,0.000017544864],"domain_scores_gemma":[0.9999037,0.000008626051,0.000046024055,0.0000075578196,0.000011239767,0.000022934895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000043892138,0.000490994,0.00019760625,0.00036738339,0.00027289332,0.00023709236,0.00028244656,0.00029514532,0.0012264258],"category_scores_gemma":[0.0000758557,0.00014808508,0.0002462169,0.00014597499,0.00020757354,0.00009486504,0.00026430865,0.00031398502,0.0006898328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000026026279,0.000005853771,0.00029264658,0.000017449538,0.000004162092,0.00010265927,0.0000039760585,0.000028725886,0.99852043,0.000054667085,0.000052381798,0.00089100405],"study_design_scores_gemma":[0.000011093621,0.00006260426,0.045331277,0.00001254533,0.00003067098,0.0012049446,0.00002154654,0.00080571574,0.9435301,0.00006169954,0.008915978,0.000011704411],"about_ca_topic_score_codex":0.0022968769,"about_ca_topic_score_gemma":0.004205881,"teacher_disagreement_score":0.0022968769,"about_ca_system_score_codex":0.00056497485,"about_ca_system_score_gemma":0.00021332238,"threshold_uncertainty_score":0.0045669675},"labels":[],"label_agreement":null},{"id":"W2170067815","doi":"10.1159/000123041","title":"FKBP Family Proteins: Immunophilins with Versatile Biological Functions","year":2008,"lang":"en","type":"review","venue":"Neurosignals","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":328,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium; University of Toronto","funders":"Biomedical Research Council","keywords":"FKBP; Peptidylprolyl isomerase; Cis-trans-Isomerases; Tetratricopeptide; Cell biology; Biology; Cyclophilin; Chemistry; Biochemistry; Isomerase; Gene","score_opus":0.07635984194024226,"score_gpt":0.300465153735949,"score_spread":0.22410531179570675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170067815","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.44289562,0.45901278,0.03593346,0.002573728,0.0010881348,0.0003336587,0.009774338,0.0038094828,0.044578772],"genre_scores_gemma":[0.84779435,0.08895017,0.009809692,0.00095363753,0.00047545088,0.00023883425,0.012138407,0.00011477154,0.039524823],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99983287,0.000015885807,0.000010285211,0.000043157812,0.000052572435,0.00004527578],"domain_scores_gemma":[0.9999261,0.000004826068,0.00002373257,0.0000038030566,0.000017833281,0.00002368161],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009600917,0.0007708795,0.00055701425,0.00080963323,0.000547621,0.0006912252,0.00028371182,0.00062101445,0.0026030443],"category_scores_gemma":[0.00014685735,0.0001402574,0.0002603934,0.0008846973,0.00026742494,0.0004033406,0.0004567944,0.00051994924,0.0023037395],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011781057,0.00022559511,0.009639443,0.0016547928,0.00015637848,0.0032218571,0.00026169527,0.0010215306,0.61785907,0.008094848,0.039682034,0.31700462],"study_design_scores_gemma":[0.00011243197,0.00037944163,0.044800572,0.00023088382,0.00018564406,0.013231215,0.00014581338,0.001991708,0.15411185,0.0031367273,0.7815838,0.00008996092],"about_ca_topic_score_codex":0.0010721883,"about_ca_topic_score_gemma":0.0006386416,"teacher_disagreement_score":0.0026030443,"about_ca_system_score_codex":0.0006667932,"about_ca_system_score_gemma":0.00027943464,"threshold_uncertainty_score":0.00870806},"labels":[],"label_agreement":null},{"id":"W2170576927","doi":"10.1128/mcb.05987-11","title":"A Novel Role for hSMG-1 in Stress Granule Formation","year":2011,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"National Medical Research Council; Australian Research Council; Griffith University; National Health and Medical Research Council; University of Rochester","keywords":"Biology; Stress granule; Genetics; Cell biology; Computational biology; Gene","score_opus":0.015121468969341358,"score_gpt":0.2252922778867368,"score_spread":0.21017080891739545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170576927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97660154,0.010779551,0.009196874,0.00039140534,0.00012275708,0.000051008272,0.00045450713,0.00020626085,0.002196161],"genre_scores_gemma":[0.9918698,0.0022536397,0.0036400617,0.00008786271,0.00004717825,0.000024405645,0.00048748485,0.000011531676,0.0015780809],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993956,0.0000076118654,0.0000044846875,0.00001956057,0.00001312954,0.000015593114],"domain_scores_gemma":[0.9999243,0.000009356899,0.000020048896,0.000011958117,0.000009982943,0.000024355133],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009590503,0.00026661053,0.0002608208,0.00017895202,0.00023985191,0.0004517436,0.000232099,0.00040014618,0.000904898],"category_scores_gemma":[0.000087986715,0.00010396717,0.00028242372,0.00011993514,0.00023972023,0.00045914986,0.00029226116,0.0003097541,0.000282129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016046903,0.000012035315,0.00056092796,0.000069137364,0.000004221724,0.00029129634,0.00002491605,0.000037836886,0.99623835,0.00049805973,0.00006848148,0.0020342183],"study_design_scores_gemma":[0.00004674248,0.00041858072,0.038240932,0.000022218657,0.000028554445,0.0022751656,0.000084830004,0.0016611007,0.94353473,0.00078783254,0.012889107,0.000010117093],"about_ca_topic_score_codex":0.00014090593,"about_ca_topic_score_gemma":0.00026463368,"teacher_disagreement_score":0.000904898,"about_ca_system_score_codex":0.00031153104,"about_ca_system_score_gemma":0.00011021919,"threshold_uncertainty_score":0.003027141},"labels":[],"label_agreement":null},{"id":"W2170728645","doi":"10.1186/1476-4598-12-84","title":"Characterization and identification of PARM-1 as a new potential oncogene","year":2013,"lang":"en","type":"article","venue":"Molecular Cancer","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Canadian Institutes of Health Research; Université du Québec à Montréal","keywords":"Biology; Cell biology; Transfection; Molecular biology; Cell culture; Genetics","score_opus":0.005891447820498951,"score_gpt":0.24278690677905196,"score_spread":0.23689545895855302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2170728645","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.989687,0.0022299439,0.0055303206,0.00020293522,0.000027859334,0.000056747795,0.0008856145,0.000048758688,0.0013307903],"genre_scores_gemma":[0.97904795,0.0014904975,0.01153361,0.00010739085,0.0000369054,0.00005934992,0.0046906043,0.000021320498,0.0030124113],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993944,0.000005421878,0.0000032134963,0.000016535518,0.000018739342,0.000016704735],"domain_scores_gemma":[0.99989045,0.000021390852,0.000029074692,0.000013167605,0.000018724453,0.000027199685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009714569,0.00025454562,0.00012500642,0.0003674601,0.0001742844,0.00032894628,0.00024813757,0.00031710585,0.001661106],"category_scores_gemma":[0.00016473148,0.00007251817,0.00025229616,0.00020907696,0.00017346059,0.0002451555,0.00017029991,0.00046534144,0.00085423124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000052983014,0.000024531535,0.000827149,0.000026911035,0.000002554631,0.00020259585,0.000011904403,0.00004091922,0.9965384,0.0002348681,0.000051780546,0.0019853231],"study_design_scores_gemma":[0.000025089153,0.00047677668,0.015409917,0.000011951862,0.0000311395,0.0045299265,0.000060762006,0.0015218444,0.9600906,0.00023829752,0.017596083,0.00000764066],"about_ca_topic_score_codex":0.00017618416,"about_ca_topic_score_gemma":0.00018669976,"teacher_disagreement_score":0.001661106,"about_ca_system_score_codex":0.0003329126,"about_ca_system_score_gemma":0.00018948907,"threshold_uncertainty_score":0.0055568814},"labels":[],"label_agreement":null},{"id":"W2171342112","doi":"10.1093/cvr/cvn357","title":"Egr-1 negatively regulates calsequestrin expression and calcium dynamics in ventricular cells","year":2008,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University","funders":"","keywords":"Calsequestrin; Phospholamban; Biology; Chromatin immunoprecipitation; Molecular biology; Calreticulin; Immunoprecipitation; Cell biology; Calcium-binding protein; Endoplasmic reticulum; Ryanodine receptor; Gene expression; Calcium; Chemistry; Promoter; Biochemistry; Gene","score_opus":0.057341107523588085,"score_gpt":0.31244159766226237,"score_spread":0.2551004901386743,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171342112","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9940128,0.002026472,0.0021213815,0.00015193496,0.00003167761,0.000008080851,0.00041012894,0.00006516917,0.0011724177],"genre_scores_gemma":[0.9934675,0.0012110737,0.0011200153,0.00012785493,0.000016828419,0.000019573747,0.0007405246,0.000042113257,0.0032546204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981326,0.000023960023,0.000017115948,0.000048226502,0.000052118434,0.000045368164],"domain_scores_gemma":[0.9998851,0.000017142253,0.000041067924,0.000017102979,0.000014792984,0.000024698946],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018985894,0.00031281228,0.000295185,0.00016583136,0.00015247554,0.0003660366,0.0002796113,0.00025113914,0.0009959498],"category_scores_gemma":[0.0001270463,0.00012880628,0.0002607191,0.00015110661,0.0002390631,0.00019850551,0.0002884546,0.00047120042,0.00041153785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054141416,0.000009792256,0.0002645098,0.000017724704,0.0000039502343,0.00004285717,0.000012307578,0.000036814425,0.9989674,0.000039045724,0.000035650268,0.00051574945],"study_design_scores_gemma":[0.000018739438,0.000113551716,0.01677088,0.000010473147,0.00002587377,0.00029581832,0.00006466583,0.0008996144,0.9788473,0.00007851707,0.002869708,0.0000047700714],"about_ca_topic_score_codex":0.00031502006,"about_ca_topic_score_gemma":0.00043620693,"teacher_disagreement_score":0.0009959498,"about_ca_system_score_codex":0.00031552382,"about_ca_system_score_gemma":0.0001461151,"threshold_uncertainty_score":0.00333184},"labels":[],"label_agreement":null},{"id":"W2171625211","doi":"10.1002/glia.21010","title":"ApoD, a glia‐derived apolipoprotein, is required for peripheral nerve functional integrity and a timely response to injury","year":2010,"lang":"en","type":"article","venue":"Glia","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":91,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Canadian Institutes of Health Research; Fonds de Recherche du Québec - Santé; Junta de Castilla y León; Ministerio de Ciencia e Innovación","keywords":"Biology; Remyelination; Regeneration (biology); Myelin; Neuroscience; Axon; Schwann cell; Angiogenesis; Cell biology; Peripheral nerve injury; Neuroglia; Wallerian degeneration; Pathology; Central nervous system; Medicine; Cancer research","score_opus":0.01812514665289943,"score_gpt":0.27764815546453947,"score_spread":0.25952300881164003,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171625211","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99382424,0.001648211,0.0033493615,0.00005598044,0.000022703765,0.000014671604,0.00026636978,0.00007669949,0.000741805],"genre_scores_gemma":[0.9923936,0.0013854823,0.0028896842,0.00003236272,0.000015902011,0.000032676795,0.00038983583,0.000017474536,0.002843042],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998976,0.00000873624,0.000013348109,0.000032855532,0.000032117827,0.000015426564],"domain_scores_gemma":[0.99984396,0.0000127813255,0.00007524133,0.000016606442,0.000020570149,0.000030754432],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008696107,0.00025287797,0.00022332245,0.00022621533,0.00013906523,0.00027577375,0.0001174032,0.0002887094,0.00063892466],"category_scores_gemma":[0.0001424957,0.00012548317,0.00019394446,0.000115597686,0.0002731622,0.00017948794,0.00021432503,0.0002925776,0.00025183664],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008141378,0.000008220774,0.00069601747,0.000022600916,0.0000020444286,0.0001202018,0.000013595219,0.000013828013,0.9979747,0.00003304396,0.000012586695,0.0010217373],"study_design_scores_gemma":[0.000020917174,0.0005452342,0.12563746,0.000021164344,0.000034351877,0.00227058,0.00012085036,0.0006888273,0.8670293,0.00024164205,0.0033740713,0.000015770434],"about_ca_topic_score_codex":0.00051980925,"about_ca_topic_score_gemma":0.0004430233,"teacher_disagreement_score":0.00063892466,"about_ca_system_score_codex":0.00020661959,"about_ca_system_score_gemma":0.00018660365,"threshold_uncertainty_score":0.0021374226},"labels":[],"label_agreement":null},{"id":"W2171706231","doi":"10.1074/jbc.m411787200","title":"Interleukin-18 Is a Pro-hypertrophic Cytokine That Acts through a Phosphatidylinositol 3-Kinase-Phosphoinositide-dependent Kinase-1-Akt-GATA4 Signaling Pathway in Cardiomyocytes","year":2004,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"National Heart, Lung, and Blood Institute","keywords":"Protein kinase B; GATA4; PI3K/AKT/mTOR pathway; Gene knockdown; Biology; Wortmannin; Signal transduction; Endocrinology; Internal medicine; LY294002; Molecular biology; Transcription factor; Cell biology; Medicine; Gene; Biochemistry","score_opus":0.035259650043083186,"score_gpt":0.2671832181204816,"score_spread":0.23192356807739845,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2171706231","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95180815,0.03274146,0.007856353,0.0005812917,0.00024040345,0.00018558133,0.0013588043,0.0002937568,0.004934222],"genre_scores_gemma":[0.97661054,0.015196879,0.00416546,0.00021509567,0.00016209092,0.00011618302,0.0011621804,0.000019611982,0.0023518875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999892,0.000014824156,0.000011147478,0.000024311184,0.000027961461,0.000029684767],"domain_scores_gemma":[0.9999058,0.000012557154,0.00004033674,0.0000049410037,0.000013206882,0.000023136572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010513391,0.00044529102,0.00022603812,0.00031519402,0.00012696032,0.00021413794,0.00010762026,0.00021725941,0.0013141255],"category_scores_gemma":[0.00010526794,0.0001504942,0.00024733637,0.00018002061,0.00017736152,0.00014378717,0.00015831993,0.00052999676,0.00037313093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008484098,0.00019002198,0.010750168,0.0003344175,0.000041508083,0.001002791,0.00005450019,0.00014373052,0.95531404,0.00023705837,0.0005600434,0.030523399],"study_design_scores_gemma":[0.00040791015,0.004344155,0.22018719,0.00012736603,0.00024888307,0.016577048,0.00016579218,0.0026166446,0.7139936,0.00087995484,0.040405657,0.000045787667],"about_ca_topic_score_codex":0.00019341483,"about_ca_topic_score_gemma":0.0002386086,"teacher_disagreement_score":0.0013141255,"about_ca_system_score_codex":0.00016683419,"about_ca_system_score_gemma":0.0001769146,"threshold_uncertainty_score":0.0043962},"labels":[],"label_agreement":null},{"id":"W2174687889","doi":"10.1139/cjc-2014-0230","title":"Noncovalent binding of a cyclic peptide inhibitor to the peptidyl-prolyl isomerase Pin1, explored by hydrogen exchange mass spectrometry","year":2014,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Cancer Research Society","keywords":"Chemistry; Prolyl isomerase; WW domain; PIN1; Peptidylprolyl isomerase; Hydrogen–deuterium exchange; Ligand (biochemistry); Stereochemistry; Isomerase; Steric effects; Circular dichroism; Peptide; Crystallography; Biophysics; Biochemistry; Mass spectrometry; Enzyme","score_opus":0.009014871154805412,"score_gpt":0.213296410182931,"score_spread":0.20428153902812557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2174687889","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99328107,0.0011781623,0.0028257768,0.000115699164,0.00003750453,0.000027334718,0.0001775456,0.000044527624,0.002312407],"genre_scores_gemma":[0.9952461,0.000988502,0.0019400498,0.0000682587,0.00001075766,0.000020200527,0.00022560143,0.000014074671,0.0014863993],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999056,0.0000080961945,0.000002568269,0.000027837374,0.000031010146,0.00002484761],"domain_scores_gemma":[0.99995387,0.000013180135,0.000014647061,0.0000049708187,0.000005158188,0.000008138901],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014234916,0.00028264054,0.00019089087,0.00007718437,0.00018042255,0.00018303869,0.00040904206,0.00029600764,0.0007822698],"category_scores_gemma":[0.00015552151,0.000121319106,0.00012981897,0.00010138098,0.00019554581,0.00019705646,0.00019178519,0.00043995993,0.0001712747],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002581152,0.00005519578,0.00021553792,0.00007649805,0.000018368202,0.000095869014,0.000024212197,0.00043001195,0.99632615,0.00022615101,0.0002068361,0.002067044],"study_design_scores_gemma":[0.000027666994,0.00022518767,0.0011961863,0.0000035107073,0.000010368427,0.000097575605,0.000024666062,0.0052649244,0.9914068,0.000058276895,0.0016748297,0.000010067841],"about_ca_topic_score_codex":0.0007464909,"about_ca_topic_score_gemma":0.00077350094,"teacher_disagreement_score":0.0007822698,"about_ca_system_score_codex":0.00032679856,"about_ca_system_score_gemma":0.00014780322,"threshold_uncertainty_score":0.0026170015},"labels":[],"label_agreement":null},{"id":"W2181981117","doi":"10.22038/ijbms.2011.4951","title":"Evaluation of Porin Interaction with Adenine Nucleotide Translocase and Cyclophilin-D Proteins after Brain Ischemia and Reperfusion","year":2011,"lang":"en","type":"article","venue":"DOAJ (DOAJ: Directory of Open Access Journals)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Porin; Voltage-dependent anion channel; Cyclophilin; Mitochondrion; Mitochondrial permeability transition pore; Biochemistry; Biology; Inner mitochondrial membrane; Blot; Adenine nucleotide translocator; Molecular biology; Cell biology; Chemistry; Bacterial outer membrane; Apoptosis; Programmed cell death; Escherichia coli","score_opus":0.18588780124497112,"score_gpt":0.49433223515065916,"score_spread":0.30844443390568804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2181981117","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99707854,0.001253289,0.0008857202,0.000055362078,0.000026697668,0.000018469123,0.0001465258,0.00001748488,0.0005179495],"genre_scores_gemma":[0.99533564,0.0008203315,0.001009795,0.0000735225,0.000029705237,0.00006898873,0.00047309484,0.000007674083,0.0021813165],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983025,0.000027519382,0.0000135469545,0.000039158607,0.000030862513,0.000058604637],"domain_scores_gemma":[0.99984074,0.000024264866,0.000048363792,0.000011040349,0.00001992299,0.00005562876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024268638,0.00027706908,0.00026523182,0.00025209345,0.00019383075,0.00021484819,0.00013320416,0.00031133686,0.0020780258],"category_scores_gemma":[0.00016455738,0.00012154919,0.00026663597,0.000174823,0.00021528066,0.00022524598,0.00014574273,0.00047237484,0.00032683252],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008899243,0.000085579835,0.0011688918,0.000071658294,0.000016487616,0.00012579649,0.000036271394,0.000015083583,0.996651,0.00003862329,0.00004283636,0.0008578522],"study_design_scores_gemma":[0.00006152847,0.0018986467,0.08507265,0.00001527109,0.00011649369,0.0009402219,0.00017654136,0.0011097507,0.9089289,0.00010453646,0.0015639773,0.0000115063995],"about_ca_topic_score_codex":0.00023544587,"about_ca_topic_score_gemma":0.0002405759,"teacher_disagreement_score":0.0020780258,"about_ca_system_score_codex":0.00015733812,"about_ca_system_score_gemma":0.00008215229,"threshold_uncertainty_score":0.0069516897},"labels":[],"label_agreement":null},{"id":"W2184268422","doi":"10.1023/a:1012209923231","title":"Endoplasmic reticulum in the heart, a forgotten organelle?","year":2001,"lang":"en","type":"review","venue":"Molecular and Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Alberta; Canadian Institutes of Health Research","funders":"","keywords":"Endoplasmic reticulum; Organelle; Cell biology; STIM1; Ryanodine receptor 2; Chemistry; Biology; Ryanodine receptor","score_opus":0.012757707307015243,"score_gpt":0.2594704198894907,"score_spread":0.24671271258247546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2184268422","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000103769344,0.9954261,0.00028216845,0.0022345858,0.0012679794,0.0000017590354,0.000008355704,0.0000128311,0.00066244433],"genre_scores_gemma":[0.0007633481,0.9958687,0.0003123136,0.001115055,0.0008140764,0.0000033284248,0.000013189924,0.000002113941,0.0011079435],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99972874,0.000054221757,0.00004350086,0.00005478102,0.00008889217,0.000029798699],"domain_scores_gemma":[0.99949443,0.0001974768,0.000047769474,0.000033749166,0.00014788003,0.00007868025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017021957,0.0012561083,0.0026985956,0.0012406411,0.00074275525,0.0025940114,0.001973529,0.0037862633,0.0022050112],"category_scores_gemma":[0.0010275225,0.00042407855,0.00036873727,0.002056982,0.0025902563,0.0072930017,0.001347282,0.0041245776,0.0035619996],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034789662,0.000052787018,0.000259567,0.008300487,0.000081390244,0.0009062907,0.00021121211,0.0006313626,0.005359603,0.02709918,0.11686343,0.8398868],"study_design_scores_gemma":[0.000021421944,0.000038334663,0.00023544989,0.001225838,0.00003476846,0.0012180402,0.00017573357,0.000093251496,0.00043070273,0.009504933,0.98700094,0.000020551948],"about_ca_topic_score_codex":0.0012724573,"about_ca_topic_score_gemma":0.002232355,"teacher_disagreement_score":0.0037862633,"about_ca_system_score_codex":0.0011932071,"about_ca_system_score_gemma":0.0014932189,"threshold_uncertainty_score":0.009002149},"labels":[],"label_agreement":null},{"id":"W2186573764","doi":"10.1379/csc-118r.1","title":"Developmental regulation and coordinate reexpression of FKBP65 with extracellular matrix proteins after lung injury suggest a specialized function for this endoplasmic reticulum immunophilin","year":2005,"lang":"en","type":"article","venue":"Cell Stress and Chaperones","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"Endoplasmic reticulum; Extracellular matrix; Downregulation and upregulation; Unfolded protein response; Tropoelastin; Protein disulfide-isomerase; Cell biology; Fibroblast; Biology; Pulmonary fibrosis; Chemistry; Molecular biology; Fibrosis; Biochemistry; Internal medicine; Medicine","score_opus":0.004114018977632512,"score_gpt":0.20771125481582026,"score_spread":0.20359723583818776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2186573764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96635145,0.008526528,0.018102072,0.0003941867,0.0001514666,0.000053349177,0.0016922067,0.0004023558,0.0043263785],"genre_scores_gemma":[0.98423314,0.0018997913,0.0046746135,0.00019782453,0.00003039692,0.00007356268,0.0011273874,0.00010213508,0.007661286],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99969256,0.000022455557,0.000033068976,0.00009302636,0.00006737776,0.00009164956],"domain_scores_gemma":[0.9995066,0.000053859298,0.00015652955,0.0000648543,0.00007935429,0.00013871677],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021368779,0.00047178444,0.00047052943,0.0011507648,0.00046439408,0.00070886133,0.0004078555,0.0006493302,0.0016299728],"category_scores_gemma":[0.000290323,0.00048676436,0.0004916656,0.00035794816,0.00042008155,0.0006742518,0.00065259135,0.0009618707,0.0008117801],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011920885,0.000009130933,0.00094395236,0.000019980345,0.0000062272666,0.0003678533,0.000024969024,0.000019979849,0.9969388,0.00037091612,0.00006773608,0.0011112298],"study_design_scores_gemma":[0.000013934903,0.00013381864,0.1338169,0.000021438238,0.00004134437,0.002358601,0.00020973952,0.0004694044,0.8580156,0.00034057233,0.0045616594,0.000017026798],"about_ca_topic_score_codex":0.0012256836,"about_ca_topic_score_gemma":0.002565951,"teacher_disagreement_score":0.0016299728,"about_ca_system_score_codex":0.0007007298,"about_ca_system_score_gemma":0.0003410399,"threshold_uncertainty_score":0.0054528117},"labels":[],"label_agreement":null},{"id":"W2200663882","doi":"10.1016/j.jamcollsurg.2015.08.321","title":"OSMR deficiency provides protection in sepsis-induced morbidity &amp; mortality in both young adult and old mice","year":2015,"lang":"en","type":"article","venue":"Journal of the American College of Surgeons","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Sepsis; Physiology; Internal medicine; Intensive care medicine","score_opus":0.037742951454623704,"score_gpt":0.2852353540774172,"score_spread":0.24749240262279348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2200663882","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93099684,0.007858702,0.004734193,0.0047104345,0.0011215353,0.00015704826,0.035486188,0.0016364482,0.013298751],"genre_scores_gemma":[0.8993946,0.011424032,0.009674059,0.001461583,0.00049003825,0.00060128066,0.018547364,0.0004122075,0.057994865],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99976856,0.000027322243,0.000035271798,0.000039007184,0.00007474934,0.00005512764],"domain_scores_gemma":[0.99956423,0.000023743674,0.00012434853,0.000029869583,0.000047070844,0.00021067238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030999517,0.0003143777,0.00039860673,0.0007424216,0.0002655704,0.00032615985,0.00036989118,0.0004296344,0.014792815],"category_scores_gemma":[0.00026900708,0.00023285883,0.00029977178,0.00027519805,0.00018848538,0.0003653482,0.0002825123,0.0007199833,0.00432997],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0121024335,0.0007527826,0.009648413,0.00047303183,0.000046904566,0.0006660675,0.00010760528,0.00023759258,0.8756229,0.0010811297,0.026358591,0.07290247],"study_design_scores_gemma":[0.0014110534,0.008418559,0.19055635,0.0006002514,0.00022831827,0.0032034682,0.000530785,0.0011856639,0.71366835,0.0010875205,0.07896089,0.00014877244],"about_ca_topic_score_codex":0.00039866506,"about_ca_topic_score_gemma":0.0009828915,"teacher_disagreement_score":0.014792815,"about_ca_system_score_codex":0.00023097754,"about_ca_system_score_gemma":0.00037033277,"threshold_uncertainty_score":0.049486935},"labels":[],"label_agreement":null},{"id":"W2205475424","doi":"10.1371/journal.pone.0145458","title":"Cyclophilin C Participates in the US2-Mediated Degradation of Major Histocompatibility Complex Class I Molecules","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Cyclophilin; Endoplasmic reticulum; Prolyl isomerase; Peptidylprolyl isomerase; Cyclophilin A; Biology; Cell biology; Major histocompatibility complex; Unfolded protein response; Endoplasmic-reticulum-associated protein degradation; Biochemistry; Immune system; Isomerase; Molecular biology; Immunology; Enzyme; Gene; PIN1","score_opus":0.135566040413346,"score_gpt":0.2857054596791459,"score_spread":0.1501394192657999,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2205475424","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99537873,0.0018879573,0.0014395247,0.000057939775,0.00001044517,0.00001390703,0.00033627122,0.000034102897,0.0008410009],"genre_scores_gemma":[0.99624395,0.00070482655,0.0012011797,0.000057735197,0.000005415453,0.000011427825,0.00046909385,0.000009338868,0.0012969506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992466,0.000010100583,0.0000055301043,0.000019044131,0.000020014457,0.000020641259],"domain_scores_gemma":[0.9999348,0.000007587723,0.000024353485,0.0000050493,0.0000101354235,0.00001808474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007940883,0.00032686428,0.00015079888,0.000293749,0.00020009643,0.0002701212,0.0000802748,0.00022648642,0.00081637816],"category_scores_gemma":[0.000097568096,0.00008108331,0.0002545051,0.00018153992,0.00014358303,0.00014779477,0.00014544453,0.00016836707,0.00019602259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000899148,0.000007172568,0.001336581,0.000032403237,0.000011641983,0.00013988906,0.000011696056,0.000050838506,0.99728537,0.00005541361,0.000043115724,0.0009359385],"study_design_scores_gemma":[0.000008177935,0.00007289053,0.06193709,0.000009019077,0.000024318299,0.0007419888,0.00004518777,0.001913607,0.9327361,0.000046219327,0.0024564757,0.0000088721645],"about_ca_topic_score_codex":0.0011863676,"about_ca_topic_score_gemma":0.0011945894,"teacher_disagreement_score":0.0011863676,"about_ca_system_score_codex":0.0003836122,"about_ca_system_score_gemma":0.00016548716,"threshold_uncertainty_score":0.002783358},"labels":[],"label_agreement":null},{"id":"W2215537962","doi":"10.1007/978-94-010-0765-8_1","title":"Calcineurin-Targeted Inhibition of Immune Reactivity","year":2001,"lang":"en","type":"book-chapter","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Calcineurin; Tacrolimus; FKBP; Immune system; Sirolimus; Drug; Pharmacology; Drug discovery; Biology; Chemistry; Transplantation; Cell biology; Immunology; Medicine; Biochemistry","score_opus":0.014797740612363061,"score_gpt":0.23538866994203772,"score_spread":0.22059092932967467,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2215537962","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17238784,0.43387258,0.055020317,0.004566631,0.0038251525,0.00024717668,0.0010030714,0.002231645,0.3268456],"genre_scores_gemma":[0.5763776,0.1727273,0.01659308,0.0018054412,0.00050087884,0.00029015998,0.000700655,0.00021638976,0.23078854],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999285,0.00000740725,0.0000027581636,0.000013207231,0.000033478074,0.000014715588],"domain_scores_gemma":[0.9999839,0.000006416001,0.000002058185,0.0000024168228,0.0000020270393,0.0000031600018],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011836205,0.0005200766,0.00033495456,0.00035538204,0.00020190618,0.00053208147,0.00055615936,0.00043412883,0.0025596262],"category_scores_gemma":[0.00007761401,0.00017595853,0.00025112118,0.00029597912,0.00025808072,0.0003307078,0.0002334172,0.001189378,0.0010399276],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028999476,0.00024672825,0.00006815072,0.00046851768,0.000036084424,0.00046823316,0.00008572343,0.0015247731,0.76035035,0.03124679,0.01407301,0.1911416],"study_design_scores_gemma":[0.000086990214,0.00043729108,0.0010890325,0.000085165586,0.000055427496,0.0015464396,0.000031833522,0.001938235,0.67873526,0.0079206675,0.3080436,0.000029999894],"about_ca_topic_score_codex":0.00041985034,"about_ca_topic_score_gemma":0.0012087321,"teacher_disagreement_score":0.0025596262,"about_ca_system_score_codex":0.0005294136,"about_ca_system_score_gemma":0.0002266694,"threshold_uncertainty_score":0.008562803},"labels":[],"label_agreement":null},{"id":"W2245508903","doi":"10.1371/journal.pone.0124117","title":"Quantitative Trait Loci and Candidate Genes for Neutrophil Recruitment in Sterile Inflammation Mapped in AXB-BXA Recombinant Inbred Mice","year":2015,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Quantitative trait locus; Biology; Candidate gene; Inbred strain; Gene; Inflammation; Genetics; Molecular biology; Immunology","score_opus":0.141962172626553,"score_gpt":0.29995077532722264,"score_spread":0.15798860270066964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2245508903","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963685,0.00020557821,0.0024782347,0.000033948447,0.0000050552876,0.00002011329,0.0006723036,0.0000477869,0.000168469],"genre_scores_gemma":[0.985873,0.0003992819,0.009032019,0.000054767836,0.00001105508,0.00013782717,0.0021342365,0.00007000532,0.0022878037],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994748,0.00009258486,0.000045902423,0.00018345306,0.00013676868,0.00006653626],"domain_scores_gemma":[0.99936897,0.00010964713,0.0003287296,0.000036745372,0.000026230098,0.00012978681],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040800072,0.0005646887,0.00034927705,0.0010746282,0.0001987487,0.00028906908,0.00031322113,0.00033974898,0.0014634423],"category_scores_gemma":[0.00026019488,0.00032412205,0.0003771862,0.0004510214,0.00029929745,0.000091214104,0.00028431675,0.00065388717,0.0002562218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027618528,0.00004840253,0.0014943754,0.000013541033,0.000011074182,0.000055715856,0.000025818228,0.0000481315,0.9972805,0.00004768894,0.000011204679,0.00068743504],"study_design_scores_gemma":[0.00043554595,0.0017041739,0.5653377,0.000045652938,0.00030876586,0.0025058012,0.00025605524,0.004211558,0.42097998,0.0004121129,0.0037148301,0.000087805034],"about_ca_topic_score_codex":0.0008297552,"about_ca_topic_score_gemma":0.0011357875,"teacher_disagreement_score":0.0014634423,"about_ca_system_score_codex":0.0002488004,"about_ca_system_score_gemma":0.00017775684,"threshold_uncertainty_score":0.004895687},"labels":[],"label_agreement":null},{"id":"W2280407519","doi":"10.1096/fasebj.23.1_supplement.812.1","title":"D‐4F attenuates calcineurin‐induced cardiac hypertrophy and heart failure","year":2009,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pediatric Oncology Group","funders":"","keywords":"Calcineurin; Internal medicine; Heart failure; Endocrinology; Muscle hypertrophy; NFAT; Medicine; Fibrosis; Cardiac function curve; Cardiology; Chemistry; Transplantation","score_opus":0.011616577591075598,"score_gpt":0.2401056204059557,"score_spread":0.2284890428148801,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2280407519","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939711,0.0028704752,0.0012962446,0.0002595891,0.00011018814,0.00005912651,0.00029720258,0.00016975842,0.0009663489],"genre_scores_gemma":[0.989131,0.0027293956,0.0021700657,0.0002256245,0.00008126264,0.00016641094,0.00075479125,0.000035745106,0.0047057904],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987733,0.000026084697,0.000012752129,0.000017390312,0.000023746128,0.000042759748],"domain_scores_gemma":[0.99982053,0.000019058189,0.000049605456,0.000014137717,0.000018336194,0.00007836401],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021520801,0.00076439034,0.00057617365,0.00051732524,0.00019586808,0.0002214111,0.00042153912,0.0005112569,0.0010648171],"category_scores_gemma":[0.00019707902,0.00020811593,0.0004541594,0.00013560014,0.00040088707,0.00021622346,0.00021331832,0.0010130502,0.0002026638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0028008292,0.0009932151,0.00034967187,0.00015533988,0.000036697445,0.00009018109,0.000021074553,0.00018131305,0.9888045,0.00010000384,0.00022305928,0.006244125],"study_design_scores_gemma":[0.001876062,0.0102835465,0.017930117,0.00005554333,0.00016629558,0.00038477464,0.00008199758,0.002342009,0.9612802,0.00023497801,0.0053337673,0.000030692783],"about_ca_topic_score_codex":0.00073363923,"about_ca_topic_score_gemma":0.0009659137,"teacher_disagreement_score":0.0010648171,"about_ca_system_score_codex":0.0002782224,"about_ca_system_score_gemma":0.00040579386,"threshold_uncertainty_score":0.0035621524},"labels":[],"label_agreement":null},{"id":"W2291905329","doi":"10.1091/mbc.e15-10-0729","title":"Inhibition of the FKBP family of peptidyl prolyl isomerases induces abortive translocation and degradation of the cellular prion protein","year":2016,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; University of Toronto","funders":"Medical Research Council; Canadian Institutes of Health Research; University of Toronto; Canada Research Chairs; University of Alberta","keywords":"FKBP; Biology; Prolyl isomerase; Endoplasmic reticulum; Chromosomal translocation; Cell biology; Scrapie; Peptidylprolyl isomerase; Proteasome; Calcineurin; Ectopic expression; PIN1; Cell culture; Isomerase; Biochemistry; Prion protein; Genetics; Transplantation; Enzyme; Disease","score_opus":0.00763165859959378,"score_gpt":0.21496457689501045,"score_spread":0.20733291829541667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2291905329","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9852378,0.007322708,0.0037082685,0.00015007584,0.00007142733,0.000031718668,0.00046312992,0.00018913575,0.0028257375],"genre_scores_gemma":[0.98984796,0.0033726697,0.0019483787,0.0000836339,0.0000150755,0.000037265072,0.00053613534,0.000021447338,0.0041373856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987257,0.000027893962,0.000013299236,0.000027508398,0.000024588764,0.00003415001],"domain_scores_gemma":[0.99994147,0.000016667149,0.00001674124,0.000006642632,0.000005338034,0.000013203121],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010255008,0.0005517317,0.00034256262,0.00018182298,0.00011548663,0.00022783119,0.00018058278,0.00032449092,0.0008308977],"category_scores_gemma":[0.00008456739,0.00008355697,0.00014630846,0.00012806691,0.00024515903,0.00012725958,0.00012948802,0.00043700438,0.00044531943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002225391,0.000044868324,0.00008665198,0.000056252746,0.000007781918,0.00009880388,0.000006891794,0.0000699176,0.9971054,0.00009374765,0.00007499239,0.0021321469],"study_design_scores_gemma":[0.00002356115,0.00037602131,0.0022187107,0.0000065030254,0.000018833915,0.00027142456,0.000010133465,0.00051059143,0.9934337,0.000040819486,0.0030850861,0.000004583267],"about_ca_topic_score_codex":0.0009913609,"about_ca_topic_score_gemma":0.0016020234,"teacher_disagreement_score":0.0009913609,"about_ca_system_score_codex":0.00034554463,"about_ca_system_score_gemma":0.00015253195,"threshold_uncertainty_score":0.002779603},"labels":[],"label_agreement":null},{"id":"W2294378932","doi":"10.1161/circ.128.suppl_22.a18619","title":"Abstract 18619: Scaffold Protein CARD11 Modulates Receptor Mediated Apoptosis in Cardiomyocytes Following Myocardial Infarction","year":2013,"lang":"en","type":"article","venue":"Circulation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; University of Toronto","funders":"","keywords":"Medicine; Apoptosis; Scaffold protein; Myocardial infarction; Scaffold; Cell biology; Receptor; Cardiology; Signal transduction; Cancer research; Internal medicine; Biomedical engineering","score_opus":0.010256641254003782,"score_gpt":0.22488510592313427,"score_spread":0.2146284646691305,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2294378932","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946402,0.0021571396,0.0011680464,0.0001379944,0.000094676696,0.00004307368,0.0006341643,0.00004446621,0.0010802489],"genre_scores_gemma":[0.99388194,0.0014413868,0.0008190807,0.000120359975,0.00004377688,0.000081587335,0.0011528917,0.000011966702,0.0024470799],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999845,0.000022082972,0.000017737282,0.00003287549,0.00002407733,0.000058161026],"domain_scores_gemma":[0.9999243,0.000007048692,0.000023644085,0.0000059501363,0.0000073049305,0.00003187238],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001636854,0.00028893515,0.0003711796,0.00016899579,0.0001883562,0.00029959236,0.0002012151,0.00027970836,0.003882285],"category_scores_gemma":[0.00012097567,0.000113820475,0.0001968636,0.00018311045,0.00026886552,0.00024013061,0.00020443634,0.00057803857,0.0008263998],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020961692,0.00016522377,0.0013212119,0.00017779475,0.000013607311,0.00028500883,0.000026845859,0.000048699272,0.992382,0.00010789454,0.00021808688,0.0031574166],"study_design_scores_gemma":[0.0004253691,0.0040215775,0.07622324,0.000040713694,0.00011678132,0.0021141255,0.00015690191,0.00086332933,0.91050684,0.00013575879,0.005379618,0.000015752163],"about_ca_topic_score_codex":0.00016444162,"about_ca_topic_score_gemma":0.00016604179,"teacher_disagreement_score":0.003882285,"about_ca_system_score_codex":0.0002518436,"about_ca_system_score_gemma":0.00015545228,"threshold_uncertainty_score":0.012987554},"labels":[],"label_agreement":null},{"id":"W2298956820","doi":"10.1161/atvb.35.suppl_1.445","title":"Abstract 445: Beraprost, a Prostacyclin Analogue, Inhibits Human Vascular Smooth Muscle Cell Migration via Activation of Exchange Protein Activated by cAMP (Epac)","year":2015,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Gibson Energy (Canada)","funders":"","keywords":"Prostacyclin; Vascular smooth muscle; Cell biology; RHOA; Cyclic adenosine monophosphate; Cell migration; Protein kinase A; Chemistry; Forskolin; Internal medicine; Endocrinology; Signal transduction; Receptor; Cell; Medicine; Biology; Biochemistry; Kinase; Smooth muscle","score_opus":0.030356320945968924,"score_gpt":0.26584397195872644,"score_spread":0.2354876510127575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2298956820","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9767104,0.007879481,0.0031613,0.0006936991,0.00038376238,0.00010539706,0.0008081879,0.0002889151,0.0099688545],"genre_scores_gemma":[0.9813269,0.0022003914,0.0022148,0.00021664148,0.00014517474,0.00006553937,0.0010424334,0.000022604698,0.0127654215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993074,0.000011597954,0.0000045924,0.000015402731,0.000017008248,0.000020524785],"domain_scores_gemma":[0.9999659,0.000010448031,0.0000068786862,0.0000031634456,0.00000393847,0.0000096398935],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008057735,0.00033669383,0.00032552148,0.00014790827,0.0001536242,0.00017762146,0.00015460304,0.00027678604,0.0062966766],"category_scores_gemma":[0.00008740451,0.000096829855,0.00019686171,0.00007433551,0.00020200458,0.00013481126,0.00009761054,0.0006703582,0.0012688659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00096575776,0.000111724934,0.00015666067,0.00016767946,0.0000078520825,0.00012992643,0.00000858606,0.000051147013,0.9926443,0.00012568761,0.00039689674,0.0052337614],"study_design_scores_gemma":[0.00020251745,0.0019887884,0.0074169454,0.000014772309,0.000028563118,0.0010609454,0.000011600959,0.0004407044,0.9833714,0.000079496436,0.0053795087,0.0000046688256],"about_ca_topic_score_codex":0.00026317508,"about_ca_topic_score_gemma":0.00022763794,"teacher_disagreement_score":0.0062966766,"about_ca_system_score_codex":0.00019715137,"about_ca_system_score_gemma":0.00020236084,"threshold_uncertainty_score":0.02106446},"labels":[],"label_agreement":null},{"id":"W2312759407","doi":"10.1139/y2012-133","title":"Electrical field stimulation induces cardiac fibroblast proliferation through the calcineurin–NFAT pathway","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Priority Academic Program Development of Jiangsu Higher Education Institutions; Nantong University; National Natural Science Foundation of China","keywords":"NFAT; Calcineurin; Cardiac fibrosis; Fibrosis; Cell growth; Myocardial fibrosis; Cell biology; Cancer research; Signal transduction; Fibroblast; Biology; Chemistry; Molecular biology; Endocrinology; Internal medicine; Medicine; Cell culture; Transplantation; Biochemistry","score_opus":0.015809199366921965,"score_gpt":0.27929497927105085,"score_spread":0.26348577990412886,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2312759407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97416794,0.012873875,0.0037381633,0.00027052552,0.00015560076,0.00010306979,0.00029701076,0.000106917956,0.008286861],"genre_scores_gemma":[0.9908552,0.0040937494,0.0018201964,0.00012591861,0.00004869098,0.000097247445,0.0003089766,0.0000065099366,0.002643524],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988544,0.000021196041,0.00000850706,0.000020172314,0.000036775516,0.00002790938],"domain_scores_gemma":[0.9999492,0.000017238308,0.000009483298,0.000005158872,0.000007978354,0.000010835536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011388702,0.00032923493,0.0002118288,0.00021557954,0.00018171985,0.00016131354,0.00008839526,0.0002538953,0.001217466],"category_scores_gemma":[0.00008663842,0.00008368112,0.00027143836,0.00015450886,0.00016385812,0.00013279491,0.0001658592,0.00043250056,0.00015006002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017762958,0.0000693548,0.00022046774,0.00009886575,0.000007285305,0.000097652905,0.000022440512,0.000046131925,0.99581426,0.00008952464,0.000076628756,0.0032797526],"study_design_scores_gemma":[0.00015897736,0.0018280315,0.022277724,0.00003679318,0.000041756117,0.00070555543,0.00008985212,0.001681,0.9653177,0.00025857837,0.0075888513,0.000015164831],"about_ca_topic_score_codex":0.00088583067,"about_ca_topic_score_gemma":0.0016623108,"teacher_disagreement_score":0.001217466,"about_ca_system_score_codex":0.00019316805,"about_ca_system_score_gemma":0.00022115879,"threshold_uncertainty_score":0.0040727854},"labels":[],"label_agreement":null},{"id":"W2315962595","doi":"10.1016/j.cjca.2012.07.697","title":"774 MMP-2 siRNA Protects Against Contractile Dysfunction in Cardiomyocytes Subjected to Ischemia/Reperfusion","year":2012,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Saskatoon Medical Imaging","funders":"","keywords":"Transfection; Contractility; Medicine; Small interfering RNA; Gene knockdown; Viability assay; Matrix metalloproteinase; Ischemia; Contraction (grammar); Cell biology; Molecular biology; Andrology; Cell culture; Internal medicine; Cell; Biology; Biochemistry","score_opus":0.010735859737194937,"score_gpt":0.2244835428487495,"score_spread":0.21374768311155457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2315962595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888337,0.0018284274,0.0025592414,0.0008156808,0.0005274968,0.00010013076,0.0009968979,0.00026818315,0.0040701935],"genre_scores_gemma":[0.9815964,0.0016190647,0.0023905577,0.0003526942,0.00012444756,0.0002428524,0.0014223978,0.00007226753,0.012179339],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994822,0.000054425847,0.00005609838,0.00008125607,0.00010018315,0.00022578947],"domain_scores_gemma":[0.99979407,0.00002714358,0.000035985166,0.000022497754,0.000027096406,0.000093251045],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040917192,0.0007648119,0.0010467392,0.00039227807,0.0004875726,0.0005572485,0.0005086472,0.0010187149,0.005376644],"category_scores_gemma":[0.0002003966,0.0004175886,0.0005955946,0.00032255703,0.000660108,0.000464977,0.00030476754,0.0020002525,0.0011486115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015703415,0.0002937236,0.0000978296,0.00009239947,0.00002552768,0.00012487265,0.00004569854,0.000057114354,0.99584717,0.0001331479,0.00037619952,0.0013359409],"study_design_scores_gemma":[0.00047049794,0.0022151673,0.0053240573,0.00002235272,0.000093963274,0.00020696472,0.00016773464,0.0012459414,0.98787516,0.000097208096,0.0022641749,0.000016826569],"about_ca_topic_score_codex":0.0022897993,"about_ca_topic_score_gemma":0.0033330445,"teacher_disagreement_score":0.005376644,"about_ca_system_score_codex":0.00044899216,"about_ca_system_score_gemma":0.0008493836,"threshold_uncertainty_score":0.017986655},"labels":[],"label_agreement":null},{"id":"W2317008040","doi":"10.1016/j.yjmcc.2016.04.004","title":"Nuclear matrix metalloproteinase-2 in the cardiomyocyte and the ischemic-reperfused heart","year":2016,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Matrix metalloproteinase; Cardiology; Internal medicine; Matrix metalloproteinase 9; Medicine","score_opus":0.005520570020355337,"score_gpt":0.21407682634639555,"score_spread":0.20855625632604022,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2317008040","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9833957,0.01237691,0.0015683527,0.00042119774,0.00012642279,0.00001011896,0.00011371634,0.00003115557,0.0019565418],"genre_scores_gemma":[0.9946286,0.0018663411,0.00046374943,0.000045774003,0.00009937296,0.000012167321,0.00012208112,0.0000058425558,0.002756049],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999871,0.000030732157,0.000009413259,0.000021902417,0.000035616893,0.000031251508],"domain_scores_gemma":[0.9998381,0.000025730715,0.000029746758,0.00001783862,0.000017354141,0.000071051494],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031064873,0.00028659028,0.0002635497,0.00040677507,0.00018248803,0.00047103042,0.0002666807,0.00036248137,0.0017286021],"category_scores_gemma":[0.00033882484,0.00023147071,0.00021510113,0.00014698078,0.0004200185,0.000535442,0.00026261937,0.00069420156,0.00023202332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018880323,0.00009401927,0.0024286886,0.00011313559,0.000030128385,0.0009921001,0.00013928594,0.00006701892,0.9890022,0.0014046764,0.00018628586,0.0036543715],"study_design_scores_gemma":[0.00054076663,0.0024064484,0.20724343,0.000060524217,0.00022219213,0.0065536564,0.00094242056,0.0035683655,0.7685658,0.0030201117,0.0068349885,0.000041331514],"about_ca_topic_score_codex":0.00050335185,"about_ca_topic_score_gemma":0.00090586895,"teacher_disagreement_score":0.0017286021,"about_ca_system_score_codex":0.0003922788,"about_ca_system_score_gemma":0.00028686255,"threshold_uncertainty_score":0.0057827234},"labels":[],"label_agreement":null},{"id":"W2318765570","doi":"10.1042/bj20112133","title":"Steric and allosteric factors prevent simultaneous binding of transferrin-binding proteins A and B to transferrin","year":2012,"lang":"en","type":"article","venue":"Biochemical Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Transferrin; Allosteric regulation; Steric effects; Chemistry; Plasma protein binding; Binding site; Biochemistry; Stereochemistry; Enzyme","score_opus":0.016947525955477966,"score_gpt":0.25767102288520466,"score_spread":0.2407234969297267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2318765570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.996439,0.00042683884,0.0017106925,0.000091013804,0.000021561176,0.00002166574,0.00005427814,0.00005732843,0.00117754],"genre_scores_gemma":[0.99738294,0.00013039014,0.0014103209,0.00007682145,0.000009248448,0.000014686696,0.00008528984,0.000019440871,0.0008707656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977595,0.000049017963,0.000018366001,0.00004184396,0.00006576572,0.000049002912],"domain_scores_gemma":[0.9996123,0.00015588761,0.000089460686,0.000046067104,0.000030097552,0.00006616857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002006287,0.00018245654,0.00021896971,0.000081662874,0.0001570358,0.0002825772,0.0003449247,0.0002984628,0.0018847819],"category_scores_gemma":[0.0004855528,0.00018441194,0.0002011234,0.000056895326,0.00042338582,0.00016259572,0.00027777103,0.00045373166,0.00036870842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018797391,0.00002953109,0.00020836819,0.000028158158,0.000003853378,0.000040545423,0.000011965094,0.00005210601,0.9985135,0.000104707775,0.000040840012,0.00077845104],"study_design_scores_gemma":[0.000054922053,0.0002325434,0.0029420448,0.000007232554,0.000010447656,0.0002674231,0.000029971727,0.0015688322,0.99281573,0.0000800088,0.0019829308,0.000007926447],"about_ca_topic_score_codex":0.0010171758,"about_ca_topic_score_gemma":0.00116167,"teacher_disagreement_score":0.0018847819,"about_ca_system_score_codex":0.00026967705,"about_ca_system_score_gemma":0.00031082082,"threshold_uncertainty_score":0.0063052177},"labels":[],"label_agreement":null},{"id":"W2318959008","doi":"10.1038/sj.onc.1204281","title":"The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways","year":2001,"lang":"en","type":"article","venue":"Oncogene","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":112,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute; Medical Research Council","keywords":"RHOA; Biology; Thrombin; Molecular biology; Cell biology; Transforming growth factor; Receptor; Signal transduction; Pertussis toxin; Thrombin receptor; Cell culture; G protein; Biochemistry; Immunology; Platelet; Genetics","score_opus":0.01523562968037273,"score_gpt":0.24131459276295422,"score_spread":0.2260789630825815,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2318959008","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9942384,0.0007889641,0.0018771727,0.0002653882,0.000060807746,0.000024183271,0.00030438285,0.00012793462,0.0023128088],"genre_scores_gemma":[0.9970401,0.0003722931,0.0004682085,0.000034752866,0.000012669414,0.000024650477,0.0004207179,0.000022950007,0.0016036142],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99951637,0.00012096569,0.000035872697,0.000039098188,0.00011516139,0.00017252113],"domain_scores_gemma":[0.99977773,0.000076315475,0.0000447802,0.00004956163,0.000010406253,0.000041262225],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020941974,0.00039631632,0.0002401835,0.0005531573,0.00029470722,0.00041936216,0.00030614733,0.00041881343,0.0018522693],"category_scores_gemma":[0.00030976618,0.00027147174,0.00041348455,0.00032865602,0.00025468884,0.00020520207,0.00027421772,0.00095416966,0.00061349146],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023774798,0.00008347092,0.00011194139,0.000009523143,0.0000049515265,0.00016947598,0.000013692037,0.000086555905,0.9980032,0.0003562666,0.000116567586,0.00080654625],"study_design_scores_gemma":[0.000033199878,0.00022658375,0.0018795019,0.000002180783,0.000012082041,0.00077843916,0.000030437517,0.001302315,0.9939902,0.000112155976,0.001628358,0.0000045464603],"about_ca_topic_score_codex":0.0008800573,"about_ca_topic_score_gemma":0.00081333215,"teacher_disagreement_score":0.0018522693,"about_ca_system_score_codex":0.00046725964,"about_ca_system_score_gemma":0.00026710134,"threshold_uncertainty_score":0.006196499},"labels":[],"label_agreement":null},{"id":"W2322489645","doi":"10.1139/y2012-032","title":"Promotion and inhibition of cardiac hypertrophy by A-kinase anchor proteins","year":2012,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"Canadian Institutes of Health Research","keywords":"Kinase; Phosphatase; Protein kinase A; Cardiac hypertrophy; Cell biology; Biology; Myocardial hypertrophy; Signal transduction; Phosphorylation; Muscle hypertrophy; Endocrinology","score_opus":0.02478150605529475,"score_gpt":0.287666661106451,"score_spread":0.2628851550511563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2322489645","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001579055,0.9944489,0.0004301799,0.00013499694,0.00017185253,0.000011416441,0.00004945493,0.000025221892,0.0031488636],"genre_scores_gemma":[0.0057273707,0.99067897,0.00053582864,0.00013371173,0.00008640358,0.000016855445,0.00009312052,0.0000047140825,0.0027230124],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99992204,0.000008324084,0.000009167485,0.00001638935,0.00003358713,0.000010401047],"domain_scores_gemma":[0.9999535,0.000011004254,0.0000095832365,0.0000020951277,0.000014191379,0.0000096519],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017980566,0.00061151193,0.0007540725,0.0012658469,0.00020102544,0.0004190537,0.00046742603,0.00047352086,0.0019683598],"category_scores_gemma":[0.00014618617,0.00015563412,0.00030244037,0.00082148955,0.00023572774,0.0005176572,0.00039977732,0.0008238048,0.002081034],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016312195,0.00017202152,0.00020917367,0.011405954,0.000105308194,0.000528648,0.000066769266,0.00037867192,0.051442053,0.0030461464,0.016883405,0.9155988],"study_design_scores_gemma":[0.000056497884,0.00038359175,0.0025785845,0.0011454043,0.00011912541,0.0022955574,0.000061144376,0.00016164152,0.020289449,0.0014374476,0.9714337,0.000037801998],"about_ca_topic_score_codex":0.00056354987,"about_ca_topic_score_gemma":0.0011157554,"teacher_disagreement_score":0.0019683598,"about_ca_system_score_codex":0.0002862787,"about_ca_system_score_gemma":0.00032208013,"threshold_uncertainty_score":0.006584823},"labels":[],"label_agreement":null},{"id":"W2325829901","doi":"10.1038/sj.cdd.4400701","title":"Promotion of growth and apoptosis in c-myc nullizygous fibroblasts by other members of the myc oncoprotein family","year":2000,"lang":"en","type":"article","venue":"Cell Death and Differentiation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research; University Health Network","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; Medical Research Council; National Institutes of Health","keywords":"Apoptosis; Proto-Oncogene Proteins c-myc; Cell growth; Cancer research; Biology; Gene; Signal transduction; Cell cycle; Cell biology; Molecular biology; Chemistry; Gene expression; Genetics","score_opus":0.0066615543958948075,"score_gpt":0.20036180486027688,"score_spread":0.19370025046438208,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2325829901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949486,0.0010308584,0.0015226654,0.00007561088,0.000023445082,0.00000963626,0.0003153667,0.00006403415,0.002009623],"genre_scores_gemma":[0.99629754,0.0005290354,0.0009564272,0.00001749091,0.000005035484,0.000011780719,0.00028598934,0.00001481553,0.0018818805],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999864,0.00002246485,0.000016595564,0.000019795729,0.000048745642,0.00002843647],"domain_scores_gemma":[0.99978083,0.000052119678,0.00004032958,0.00004822853,0.000018682806,0.00005986445],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013922193,0.0004347569,0.00016239012,0.00051325443,0.00021047227,0.0002556998,0.00014567452,0.00020755136,0.00097004534],"category_scores_gemma":[0.00014342745,0.00010185531,0.00023757615,0.00021387124,0.00017522585,0.00013749984,0.00013995518,0.00045719102,0.00025438695],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009444905,0.000012959706,0.0002866121,0.000008280143,0.0000029055338,0.00011936655,0.0000067023316,0.000022017215,0.9986719,0.000103356746,0.000019660154,0.0006519039],"study_design_scores_gemma":[0.000013288928,0.000108167354,0.0045629432,0.000002458833,0.00001225813,0.0009235995,0.000023250155,0.00051710906,0.992416,0.00006485731,0.0013533588,0.0000027429794],"about_ca_topic_score_codex":0.00062871445,"about_ca_topic_score_gemma":0.00093817094,"teacher_disagreement_score":0.00097004534,"about_ca_system_score_codex":0.00020589195,"about_ca_system_score_gemma":0.00015073102,"threshold_uncertainty_score":0.0032451153},"labels":[],"label_agreement":null},{"id":"W2331525531","doi":"10.1177/1073858414546000","title":"Secretory Leukocyte Protease Inhibitor (SLPI)","year":2014,"lang":"en","type":"review","venue":"The Neuroscientist","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"SLPI; Neuroprotection; Protease inhibitor (pharmacology); Central nervous system; Immunology; Microglia; Multiple sclerosis; Biology; Myelin; Pharmacology; Inflammation; Neuroscience; Virus","score_opus":0.034386514632056726,"score_gpt":0.31566248478891235,"score_spread":0.2812759701568556,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2331525531","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041385528,0.9958573,0.0002961139,0.00029439013,0.00030122593,0.0000084227095,0.000042794123,0.000022809127,0.002763119],"genre_scores_gemma":[0.0036152736,0.99136204,0.0005114858,0.00040830218,0.00022079395,0.000018150406,0.00012704912,0.000004476007,0.003732394],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.999887,0.000011959815,0.000016128954,0.000023165434,0.00004708308,0.000014678984],"domain_scores_gemma":[0.9999088,0.000031149553,0.000016886206,0.0000037046418,0.00002158957,0.000017818831],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002595888,0.0008868035,0.00082250306,0.0016894711,0.00025463957,0.000942669,0.0005691875,0.0008706105,0.0033424841],"category_scores_gemma":[0.00029859346,0.00018364671,0.0003546501,0.001259954,0.00043533728,0.0009067299,0.0005576483,0.0015766947,0.0038280785],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011419745,0.00008637785,0.00023168794,0.0071015162,0.000059862894,0.0005062443,0.00005276422,0.00015735686,0.008585233,0.0027871174,0.026640644,0.9536771],"study_design_scores_gemma":[0.000020883568,0.000094198636,0.00057189935,0.000660579,0.000041227013,0.0023714348,0.000026909793,0.00004050815,0.0029811081,0.0009345101,0.99224406,0.000012640617],"about_ca_topic_score_codex":0.00062648434,"about_ca_topic_score_gemma":0.0010456154,"teacher_disagreement_score":0.0033424841,"about_ca_system_score_codex":0.00042541878,"about_ca_system_score_gemma":0.00052629545,"threshold_uncertainty_score":0.011181712},"labels":[],"label_agreement":null},{"id":"W2335714135","doi":"10.1107/s0108767310099599","title":"The thermodynamic influence of trapped water molecules on a protein-ligand interaction","year":2010,"lang":"en","type":"article","venue":"Acta Crystallographica Section A Foundations of Crystallography","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Oxford; McGill University","keywords":"Molecule; Chemistry; Ligand (biochemistry); Chemical physics; Crystallography; Calorimetry; Molecular dynamics; Thermodynamics; Physical chemistry; Computational chemistry; Physics; Biochemistry; Organic chemistry","score_opus":0.006258581648553937,"score_gpt":0.2418753658258884,"score_spread":0.23561678417733445,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2335714135","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9968516,0.0002114658,0.0020629442,0.000089318586,0.00001618308,0.0000041356343,0.000040744828,0.000030586278,0.0006929967],"genre_scores_gemma":[0.9993506,0.0001236389,0.0003279842,0.000014892202,0.0000034255556,0.0000035429134,0.000029230096,0.000012742008,0.0001339225],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998863,0.000019696246,0.000004540868,0.000028351507,0.00003343891,0.000027663335],"domain_scores_gemma":[0.9997249,0.0001468462,0.00003426533,0.000020338744,0.000021812133,0.00005171035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030486373,0.00022703514,0.00028708062,0.00018222477,0.0005770378,0.00074454356,0.0004020797,0.00028163637,0.0014645772],"category_scores_gemma":[0.0008730365,0.00027152998,0.00019332889,0.00019850892,0.0013219047,0.0010511086,0.0005358252,0.0006911327,0.00015434131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011860393,0.00018098559,0.008414626,0.00019140846,0.00015178419,0.00053835835,0.00057419116,0.04440431,0.92203164,0.008991776,0.00040212195,0.012932775],"study_design_scores_gemma":[0.0002874251,0.0010283497,0.017627677,0.000034076944,0.00019448769,0.00038211507,0.0008543971,0.2515997,0.7149756,0.010427942,0.0023598354,0.00022842127],"about_ca_topic_score_codex":0.0012948125,"about_ca_topic_score_gemma":0.0016275002,"teacher_disagreement_score":0.0014645772,"about_ca_system_score_codex":0.00041794401,"about_ca_system_score_gemma":0.00046864292,"threshold_uncertainty_score":0.004899502},"labels":[],"label_agreement":null},{"id":"W2372326229","doi":"","title":"Molecular Mechanisms of Neutrophils Adhesion to ECV304 Induced by Hypoxia-Reoxygenation","year":2004,"lang":"en","type":"article","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"CAE (Canada)","funders":"","keywords":"P70-S6 Kinase 1; Cell biology; Cell adhesion molecule; Hypoxia (environmental); Cell adhesion; Signal transduction; Biology; Chemistry; Adhesion; Molecular biology; PI3K/AKT/mTOR pathway","score_opus":0.010145022952500344,"score_gpt":0.2421501782018397,"score_spread":0.23200515524933937,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2372326229","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9680712,0.02327193,0.0043906416,0.0005151912,0.00009305339,0.00012150799,0.0004518224,0.000092395305,0.0029922293],"genre_scores_gemma":[0.98941654,0.0060156453,0.0012010053,0.00012829692,0.000030087505,0.00012283918,0.00043690874,0.0000041200246,0.0026444476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998252,0.000031690135,0.000009913193,0.000025706957,0.00004535953,0.00006219289],"domain_scores_gemma":[0.9999672,0.000003416788,0.0000132959685,0.0000024074798,0.0000065487034,0.0000070689885],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009950252,0.00037157067,0.00031414253,0.00013836421,0.00019655206,0.00020839689,0.00027116676,0.00044069826,0.0009950722],"category_scores_gemma":[0.000071604976,0.00013080172,0.000363106,0.00010089664,0.00012478835,0.00025153573,0.00016442689,0.00043630422,0.00020821081],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00043218324,0.00007205957,0.0005003261,0.00028339608,0.000019408355,0.0003613777,0.00003036674,0.000113182185,0.9947267,0.0003750085,0.00020132487,0.0028845442],"study_design_scores_gemma":[0.00010411818,0.0012255006,0.08893685,0.00006391283,0.00011446744,0.0017361713,0.00017811103,0.004016825,0.8978033,0.0004941696,0.0053007635,0.000025707237],"about_ca_topic_score_codex":0.0007913249,"about_ca_topic_score_gemma":0.0006102148,"teacher_disagreement_score":0.0009950722,"about_ca_system_score_codex":0.0003097042,"about_ca_system_score_gemma":0.00015723913,"threshold_uncertainty_score":0.0033288598},"labels":[],"label_agreement":null},{"id":"W2395783170","doi":"","title":"Étude du rôle de PIN1 dans la régulation de la signalisation NOTCH et la croissance des cellules pancréatiques tumorales humaines","year":2016,"lang":"fr","type":"article","venue":"Knowledge UdeS (Institutional Deposit of the University of Sherbrooke)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Chemistry","score_opus":0.009827423785252625,"score_gpt":0.22435001043077815,"score_spread":0.21452258664552554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2395783170","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9690843,0.01540097,0.007760563,0.00027450535,0.00011592956,0.000058392638,0.00076879817,0.000082551094,0.006454],"genre_scores_gemma":[0.9747833,0.0076481113,0.0043435395,0.00017873912,0.000018620905,0.00009100269,0.0010655046,0.000029687953,0.011841578],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978465,0.00003244785,0.000012675002,0.00006582408,0.00006754687,0.000036837617],"domain_scores_gemma":[0.9998617,0.000045412486,0.000023918785,0.000013462173,0.00003017957,0.000025326015],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031233547,0.00023884643,0.0003024542,0.00032090285,0.00031898517,0.0007892964,0.000219345,0.00041258548,0.002968703],"category_scores_gemma":[0.00030873282,0.00025445584,0.00039127748,0.0003175648,0.00025822644,0.00050489657,0.00028190447,0.0005810656,0.00067251496],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005703972,0.000033523847,0.0024982446,0.00021257935,0.000020549413,0.00034903214,0.00011865078,0.0002145298,0.98564327,0.0006411748,0.00011082739,0.00958717],"study_design_scores_gemma":[0.000027706867,0.0004279423,0.028096516,0.000038546536,0.00006731887,0.0011653958,0.0003411637,0.0015643926,0.9487745,0.00026024977,0.019213988,0.00002234111],"about_ca_topic_score_codex":0.0012039136,"about_ca_topic_score_gemma":0.001143741,"teacher_disagreement_score":0.002968703,"about_ca_system_score_codex":0.00050327345,"about_ca_system_score_gemma":0.00038873943,"threshold_uncertainty_score":0.009931266},"labels":[],"label_agreement":null},{"id":"W2398648203","doi":"10.3727/000000001783986387","title":"Inhibition of Cytokine Production and Cytokine-Stimulated T-Cell Activation by FK506 (Tacrolimus)1","year":2001,"lang":"en","type":"article","venue":"Cell Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Cytokine; Ionomycin; T cell; Chemistry; Interleukin 2; Cell growth; Calcineurin; Molecular biology; Stimulation; Cell biology; Biology; Endocrinology; Internal medicine; Immunology; Immune system; Transplantation; Medicine; Biochemistry","score_opus":0.008400387413232919,"score_gpt":0.22139200897412903,"score_spread":0.2129916215608961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2398648203","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98615044,0.005160897,0.004287105,0.00009312344,0.00010972528,0.00015302692,0.00069366506,0.000115655166,0.003236376],"genre_scores_gemma":[0.98785955,0.0025789714,0.004876162,0.000074058116,0.00008568081,0.00026552638,0.0011049203,0.000024736153,0.0031302234],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995297,0.00014405693,0.00006849092,0.00005367477,0.00007361176,0.00013046472],"domain_scores_gemma":[0.9998803,0.00004588992,0.00002387857,0.000018075909,0.000016711649,0.000015226292],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023999717,0.0006544031,0.0005573834,0.00020254093,0.00014817533,0.0003280015,0.0002389665,0.00026978223,0.0012586297],"category_scores_gemma":[0.00017840887,0.00014653018,0.0003074132,0.00019316933,0.00022109425,0.0001231024,0.00016564362,0.0006203304,0.00056225795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021664682,0.000054122876,0.00009993291,0.000048844115,0.000004978661,0.000037424055,0.000008239686,0.00007613102,0.99823964,0.000032761975,0.000034095825,0.0011470369],"study_design_scores_gemma":[0.000028041357,0.0006865804,0.0021944868,0.000005679696,0.000018258348,0.00011594135,0.0000067174797,0.0006081988,0.9949228,0.000009222927,0.0014011295,0.0000029954454],"about_ca_topic_score_codex":0.00052345777,"about_ca_topic_score_gemma":0.0012278277,"teacher_disagreement_score":0.0012586297,"about_ca_system_score_codex":0.00020279486,"about_ca_system_score_gemma":0.00020009835,"threshold_uncertainty_score":0.0042105913},"labels":[],"label_agreement":null},{"id":"W2405164770","doi":"10.1111/jeu.12329","title":"Phenotypic Characterization of a <i>Leishmania donovani</i> Cyclophilin 40 Null Mutant","year":2016,"lang":"en","type":"article","venue":"Journal of Eukaryotic Microbiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Seventh Framework Programme; Fondation pour la Recherche Médicale; Leibniz-Gemeinschaft; Agence Nationale de la Recherche; Deutscher Akademischer Austauschdienst; Canadian Institutes of Health Research; European Commission","keywords":"Biology; Cell biology; Mutant; Leishmania donovani; Parasite hosting; Intracellular parasite; Amastigote; Intracellular; Leishmania; Genetics; Gene; Leishmaniasis","score_opus":0.00734605939000064,"score_gpt":0.21265004735130472,"score_spread":0.20530398796130409,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2405164770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948055,0.00029381624,0.0021880968,0.00009299163,0.000018763205,0.000021737322,0.0013942687,0.00008283714,0.001101967],"genre_scores_gemma":[0.99079204,0.00031548465,0.0023848454,0.00006135841,0.0000063470475,0.000045747973,0.0017565202,0.00010242982,0.0045352154],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999045,0.000012911476,0.000011044613,0.000022660972,0.000027642533,0.000021172202],"domain_scores_gemma":[0.9998012,0.000035863286,0.0000646139,0.00001850967,0.000018621107,0.000061286104],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000079001264,0.00033889365,0.00018458362,0.00030959083,0.00013507492,0.00025205404,0.00020914535,0.00031936096,0.0014892707],"category_scores_gemma":[0.000109661254,0.00014057886,0.00021871908,0.00016320462,0.00028145438,0.00012367046,0.00027361469,0.0004178205,0.00056365493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000189297,0.000008596597,0.00010380928,0.000010739967,0.0000015688072,0.00010491092,0.000008421018,0.00001414088,0.9994741,0.00004372145,0.000012631599,0.00019850126],"study_design_scores_gemma":[0.000009975838,0.00015699981,0.015253341,0.000007182257,0.000017125169,0.0021924963,0.00007817384,0.0007148657,0.97916496,0.000071534,0.002322905,0.000010478085],"about_ca_topic_score_codex":0.00061449065,"about_ca_topic_score_gemma":0.00066311343,"teacher_disagreement_score":0.0014892707,"about_ca_system_score_codex":0.00017052983,"about_ca_system_score_gemma":0.00011664474,"threshold_uncertainty_score":0.004982114},"labels":[],"label_agreement":null},{"id":"W2406624411","doi":"10.1097/j.pain.0000000000000258","title":"Molecular genetic mechanisms of allelic specific regulation of murine Comt expression","year":2015,"lang":"en","type":"article","venue":"Pain","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; McGill University Health Centre; McGill University and Génome Québec Innovation Centre; University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Dental and Craniofacial Research; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Allele; Expression (computer science); Genetics; Biology; Catechol-O-methyl transferase; Neuroscience; Gene; Computer science","score_opus":0.017691422125330744,"score_gpt":0.2348301983415567,"score_spread":0.21713877621622596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2406624411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98179686,0.0012694262,0.013985526,0.00017287342,0.000051749877,0.00006179218,0.0008685119,0.0002722024,0.0015210578],"genre_scores_gemma":[0.98806214,0.0008895467,0.0066776574,0.000078763595,0.000017864813,0.00008930781,0.00088794227,0.00006867728,0.003228094],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974936,0.00003224878,0.00003097474,0.0000847281,0.0000659541,0.000036814195],"domain_scores_gemma":[0.99967647,0.00003079826,0.00016757305,0.000041405623,0.000023808268,0.000059906917],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017528018,0.0004475686,0.00018305982,0.00038341986,0.00011590818,0.0003035913,0.0002941531,0.0002772641,0.0011423277],"category_scores_gemma":[0.00014862519,0.00022567376,0.00032217902,0.00012066897,0.00028885063,0.00019437583,0.00023758292,0.00066275493,0.00037844214],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000635544,0.000011022474,0.00019312483,0.000015103383,0.000003532583,0.000062184015,0.0000051344987,0.000046136687,0.9985714,0.00019837607,0.000014763324,0.00081559946],"study_design_scores_gemma":[0.000021350914,0.00027108451,0.0045739887,0.0000071405657,0.00001883906,0.0003549433,0.000015731051,0.0009817989,0.9921078,0.00012214566,0.0015174911,0.000007574955],"about_ca_topic_score_codex":0.00018033192,"about_ca_topic_score_gemma":0.00028983987,"teacher_disagreement_score":0.0011423277,"about_ca_system_score_codex":0.00025714468,"about_ca_system_score_gemma":0.00014949575,"threshold_uncertainty_score":0.0038214326},"labels":[],"label_agreement":null},{"id":"W2409808558","doi":"10.1189/jlb.3ru0215-045r","title":"The role of EMMPRIN in T cell biology and immunological diseases","year":2015,"lang":"en","type":"review","venue":"Journal of Leukocyte Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Canadian Institutes of Health Research; Multiple Sclerosis Society; Multiple Sclerosis Society of Canada; University of Calgary","keywords":"Inducer; Biology; Matrix metalloproteinase; Disease; Immunology; Pathogenesis; Cell; Cell biology; Medicine; Gene; Genetics; Pathology","score_opus":0.02690674169871501,"score_gpt":0.3327592366411935,"score_spread":0.3058524949424785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2409808558","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022574395,0.99819773,0.00018416726,0.00027559226,0.00016773002,0.000002776703,0.000014801563,0.000008333235,0.0009232263],"genre_scores_gemma":[0.0011772766,0.9974611,0.0002161146,0.00015214104,0.00019918088,0.000004098073,0.000024953268,0.000001501049,0.0007637503],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998863,0.000015797896,0.00001820216,0.000021057682,0.0000425622,0.00001601541],"domain_scores_gemma":[0.99984145,0.000055827513,0.000025667812,0.0000057135703,0.000045511755,0.000025815598],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003584944,0.00056663965,0.0008228551,0.0017770783,0.00026701856,0.0009193355,0.0005198058,0.0009430041,0.002199955],"category_scores_gemma":[0.00040804528,0.00019516284,0.00030825372,0.001604035,0.00039516625,0.0011042452,0.00065636187,0.0012881083,0.00164814],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007186871,0.000044393084,0.00027026216,0.008255148,0.00005492688,0.00037023055,0.00006672236,0.00028483183,0.005323278,0.0042289547,0.020940825,0.9600886],"study_design_scores_gemma":[0.00000728956,0.00005280852,0.001041967,0.0014688219,0.00006418065,0.0023166107,0.000052643943,0.000089761204,0.0014303428,0.0020944728,0.99136657,0.000014492485],"about_ca_topic_score_codex":0.00050823134,"about_ca_topic_score_gemma":0.00068282295,"teacher_disagreement_score":0.002199955,"about_ca_system_score_codex":0.00048269026,"about_ca_system_score_gemma":0.0006973762,"threshold_uncertainty_score":0.0073595643},"labels":[],"label_agreement":null},{"id":"W2410485947","doi":"10.1097/00007890-200402150-00008","title":"Monitoring Of NFAT-Regulated Gene Expression in the Peripheral Blood of Allograft Recipients: A Novel Perspective Towards Individual Optimized Drug Doses of Cyclosporine A.","year":2004,"lang":"en","type":"letter","venue":"Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Liver transplantation; Therapeutic drug monitoring; Calcineurin; Nephrotoxicity; Ciclosporin; Transplantation; Internal medicine; Immunosuppression; Drug; Heart transplantation; Incidence (geometry); Chronic allograft nephropathy; Tacrolimus; Immunosuppressive drug; Gastroenterology; Urology; Kidney; Kidney transplantation; Pharmacology","score_opus":0.017171057924220835,"score_gpt":0.2656399391568532,"score_spread":0.24846888123263236,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410485947","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.74733686,0.10705583,0.1385384,0.0023580964,0.0003558713,0.0002569557,0.00064247655,0.0007163408,0.0027391256],"genre_scores_gemma":[0.8449715,0.024020402,0.12736051,0.0008844796,0.0004797083,0.00019796898,0.00035324146,0.000058160327,0.0016741327],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996675,0.0001166518,0.00002030866,0.00007032224,0.00010341906,0.0000217617],"domain_scores_gemma":[0.9996568,0.00009518471,0.00008763919,0.000033397395,0.00006283554,0.00006423626],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009465867,0.00048528326,0.0006464059,0.00046683248,0.00012707345,0.0006938894,0.00035495235,0.0005610382,0.0005618695],"category_scores_gemma":[0.0004796672,0.0001964196,0.00020302625,0.0003071627,0.00041109222,0.0005284975,0.00021483305,0.0010017301,0.0001387959],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00092280045,0.00010509946,0.0030816654,0.00016391452,0.000021905142,0.00005803557,0.000027045835,0.00019293177,0.9633385,0.00017997118,0.00017578738,0.03173227],"study_design_scores_gemma":[0.0001739234,0.0069095353,0.04465458,0.00008541495,0.0002019472,0.0018810855,0.000105936706,0.008297877,0.9260149,0.0011870601,0.010435798,0.00005187739],"about_ca_topic_score_codex":0.00015061077,"about_ca_topic_score_gemma":0.00026405777,"teacher_disagreement_score":0.0009465867,"about_ca_system_score_codex":0.00031152184,"about_ca_system_score_gemma":0.00024737412,"threshold_uncertainty_score":0.005006075},"labels":[],"label_agreement":null},{"id":"W2410582071","doi":"10.1189/jlb.69.5.803","title":"Phosphatidylinositol 3-kinase inhibitors prevent mouse cytotoxic T-cell development in vitro","year":2001,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cytotoxic T cell; Biology; CTL*; CD28; T cell; CD8; Cell biology; Granzyme A; Perforin; Granzyme; CD3; Granzyme B; IL-2 receptor; Molecular biology; Immunology; Antigen; Immune system; In vitro; Biochemistry","score_opus":0.011339196127327743,"score_gpt":0.25207311442565844,"score_spread":0.24073391829833068,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410582071","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9662547,0.005387865,0.011719142,0.00028379928,0.00033881978,0.00021003622,0.002311972,0.00096649455,0.012527276],"genre_scores_gemma":[0.97358114,0.0024829973,0.0052682133,0.00020433022,0.00008508974,0.0002891577,0.0055234362,0.00015075723,0.012414986],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99937856,0.000115916424,0.000076652475,0.000075487704,0.00016734315,0.00018597717],"domain_scores_gemma":[0.9994716,0.00017891572,0.00009133496,0.00011231681,0.00005155963,0.00009418886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028471768,0.0008447539,0.0006466543,0.00039410422,0.00017774887,0.00060031004,0.0005889898,0.00037580437,0.002406753],"category_scores_gemma":[0.0004041982,0.00029831176,0.00040317242,0.00025092947,0.00020162744,0.00024521045,0.00036401165,0.0015980554,0.0020890327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000377227,0.0002602721,0.00010175221,0.00006541303,0.000010079466,0.000055131743,0.000023062954,0.00021529278,0.9960932,0.00017666403,0.00019242245,0.0024293843],"study_design_scores_gemma":[0.000053085954,0.00065021316,0.0005795408,0.0000082309425,0.000016198888,0.00007498009,0.0000055986725,0.0010007299,0.99502975,0.000044519704,0.0025342153,0.0000028505858],"about_ca_topic_score_codex":0.0007563852,"about_ca_topic_score_gemma":0.0012222595,"teacher_disagreement_score":0.002406753,"about_ca_system_score_codex":0.0005721671,"about_ca_system_score_gemma":0.0005496319,"threshold_uncertainty_score":0.008051395},"labels":[],"label_agreement":null},{"id":"W2412143945","doi":"10.1385/0-89603-258-2:205","title":"A Nonradioactive Method for the Detection of Single-Strand Conformational Polymorphisms (SSCP)","year":2003,"lang":"en","type":"review","venue":"Humana Press eBooks","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital of Western Ontario; Western University","funders":"","keywords":"Single-strand conformation polymorphism; Genetics; DNA; Sequence (biology); Point mutation; Restriction fragment length polymorphism; Biology; DNA sequencing; Molecular biology; Southern blot; Computational biology; Mutation; Gene; Polymerase chain reaction","score_opus":0.11703050490125735,"score_gpt":0.35163011577263614,"score_spread":0.2345996108713788,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2412143945","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001570237,0.94444394,0.035127122,0.00060690084,0.0014005958,0.00020892461,0.00017694716,0.0004867462,0.015978558],"genre_scores_gemma":[0.00644407,0.9337377,0.036094625,0.0007725752,0.000567554,0.00036907944,0.00050800596,0.000066502245,0.02143983],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990392,0.00018214903,0.000059903447,0.00023002594,0.00043715994,0.00005156756],"domain_scores_gemma":[0.9993197,0.00036326484,0.00008044097,0.000043893742,0.00014505746,0.000047629488],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001337643,0.002311565,0.002648447,0.0058173337,0.0005297594,0.0010061321,0.0021188124,0.0021037583,0.007149224],"category_scores_gemma":[0.0007905196,0.0005848536,0.0005234924,0.0033305427,0.0013575921,0.0013183659,0.000685871,0.0022717416,0.015923996],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011605045,0.00026465516,0.0003479829,0.007828984,0.00007277296,0.0008512305,0.000081697486,0.00025339337,0.15199889,0.004360945,0.016330875,0.81749254],"study_design_scores_gemma":[0.000031958665,0.00024496467,0.0012680985,0.00064605207,0.000086583495,0.0056700082,0.00006820403,0.00020725327,0.06853757,0.0021807775,0.92099667,0.000061824045],"about_ca_topic_score_codex":0.00049496425,"about_ca_topic_score_gemma":0.00090305816,"teacher_disagreement_score":0.007149224,"about_ca_system_score_codex":0.00065551954,"about_ca_system_score_gemma":0.00058960094,"threshold_uncertainty_score":0.023916543},"labels":[],"label_agreement":null},{"id":"W2412986543","doi":"10.1038/nsmb.3234","title":"Heavy lessons in protein allostery","year":2016,"lang":"en","type":"article","venue":"Nature Structural & Molecular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"Allosteric regulation; Hydrogen–deuterium exchange; Chemistry; Posttranslational modification; Computational biology; Mass spectrometry; Covalent bond; Biochemistry; Biophysics; Enzyme; Biology","score_opus":0.0061609102817031065,"score_gpt":0.3064472651267111,"score_spread":0.300286354845008,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2412986543","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.24232005,0.15851507,0.09541442,0.34532675,0.021174492,0.000051386683,0.00063181634,0.0016248359,0.13494118],"genre_scores_gemma":[0.8809381,0.042434726,0.008129741,0.02493401,0.009444671,0.00005907855,0.00026618212,0.00039230523,0.0334012],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996158,0.000060883536,0.000016799064,0.00010111143,0.000108244516,0.00009719331],"domain_scores_gemma":[0.9982369,0.0006813231,0.00010659272,0.00046902188,0.00019555376,0.00031055996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0020012017,0.00043329436,0.00074379577,0.00056070596,0.0013215427,0.001489694,0.0011599815,0.0018581952,0.007096063],"category_scores_gemma":[0.003868305,0.00026452672,0.00036420618,0.000417806,0.006450449,0.007422047,0.0022830095,0.0059328014,0.001821991],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005514258,0.00010683221,0.0015162828,0.00037980019,0.00008046181,0.000658081,0.00072327495,0.0031694316,0.026096158,0.7705147,0.035365634,0.16083783],"study_design_scores_gemma":[0.00006143996,0.00010126202,0.0013754801,0.000070742666,0.000017177455,0.00041912764,0.00031803263,0.0015220422,0.0053790887,0.88237125,0.108335294,0.000028946004],"about_ca_topic_score_codex":0.0005822007,"about_ca_topic_score_gemma":0.00053835,"teacher_disagreement_score":0.007096063,"about_ca_system_score_codex":0.0013504615,"about_ca_system_score_gemma":0.00059009535,"threshold_uncertainty_score":0.023738682},"labels":[],"label_agreement":null},{"id":"W2416762270","doi":"10.1385/1-59259-046-2:181","title":"Expression of MMPs and TIMPs in Mammalian Cells","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Matrix metalloproteinase; Transfection; Cell culture; Cell biology; Baby hamster kidney cell; Gene expression; HEK 293 cells; Biology; Luciferase; Mutant; Recombinant DNA; Chemistry; Molecular biology; Computational biology; Gene; Biochemistry; Genetics","score_opus":0.026957227389259823,"score_gpt":0.25319745290815787,"score_spread":0.22624022551889805,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2416762270","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.31883276,0.06715097,0.48778442,0.00323797,0.0055033728,0.0029992356,0.042330936,0.0045150076,0.06764534],"genre_scores_gemma":[0.3551065,0.064596735,0.42671612,0.00080072274,0.00063653855,0.0025540276,0.057461843,0.0006925278,0.09143501],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992155,0.000116053685,0.00014790305,0.00011324093,0.00032078614,0.000086525855],"domain_scores_gemma":[0.9998343,0.000035009023,0.000023221766,0.00004706964,0.00003932306,0.000021041995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007909389,0.0004524836,0.0005793919,0.000536829,0.00041904647,0.0011777107,0.0006700343,0.00050860934,0.0032569047],"category_scores_gemma":[0.00038279407,0.00039436654,0.00051512255,0.0008453143,0.00038901562,0.00052422343,0.00041746756,0.001375141,0.0065014847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000105736,0.00004489068,0.00010588282,0.000360305,0.000010200306,0.00013133169,0.000087310815,0.00018017596,0.9873678,0.0024256024,0.0014803143,0.0077004475],"study_design_scores_gemma":[0.000051382816,0.00025803034,0.00095753034,0.000051634663,0.000033643693,0.0006348233,0.00007994306,0.0009827319,0.81752676,0.0005628333,0.17883798,0.000022695876],"about_ca_topic_score_codex":0.0006772872,"about_ca_topic_score_gemma":0.0010844924,"teacher_disagreement_score":0.0032569047,"about_ca_system_score_codex":0.0005023128,"about_ca_system_score_gemma":0.0005608647,"threshold_uncertainty_score":0.010895491},"labels":[],"label_agreement":null},{"id":"W2432195883","doi":"10.1385/1-59259-184-1:183","title":"Proteolytic Fragments of Calcium-Binding Proteins","year":2003,"lang":"en","type":"article","venue":"Humana Press eBooks","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Toronto","funders":"","keywords":"Calmodulin; Helix (gastropod); Calcium-binding protein; Chemistry; EF hand; Proteolysis; Peptide; Protein structure; Biochemistry; Biophysics; Stereochemistry; Crystallography; Calcium; Biology","score_opus":0.0578068302613937,"score_gpt":0.28876948757728044,"score_spread":0.23096265731588672,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2432195883","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.89730537,0.036356445,0.040759653,0.0009466412,0.0007274747,0.0004833416,0.008234913,0.00025658222,0.014929657],"genre_scores_gemma":[0.8696607,0.014864245,0.045000385,0.00081838935,0.00028384564,0.00038739794,0.038698137,0.00015685211,0.030129934],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997775,0.000029656072,0.00001896796,0.000054865992,0.00006674246,0.000052309573],"domain_scores_gemma":[0.999742,0.000088875124,0.000042217594,0.000027147498,0.00004208369,0.000057753223],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002977035,0.0005361067,0.00039133793,0.00033088,0.00018623286,0.000308563,0.00039296187,0.00038091972,0.0037922394],"category_scores_gemma":[0.0003711209,0.00014493299,0.00048594797,0.00035052063,0.0001879135,0.00022671002,0.00024137844,0.00075525156,0.0021868567],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041978757,0.00007512948,0.00027698636,0.00019642136,0.000029155528,0.00038405723,0.00003424276,0.00011380428,0.99254394,0.00042242932,0.000463569,0.0050406223],"study_design_scores_gemma":[0.00018981413,0.00049579126,0.007615183,0.000084331594,0.00006384334,0.002195687,0.000056747827,0.0011770624,0.9517515,0.0005232012,0.03582945,0.00001737223],"about_ca_topic_score_codex":0.0004142249,"about_ca_topic_score_gemma":0.00041858977,"teacher_disagreement_score":0.0037922394,"about_ca_system_score_codex":0.00027597524,"about_ca_system_score_gemma":0.00018057624,"threshold_uncertainty_score":0.012686253},"labels":[],"label_agreement":null},{"id":"W2438113208","doi":"10.1111/gtc.12383","title":"Cyclophilin PpiB is involved in motility and biofilm formation via its functional association with certain proteins","year":2016,"lang":"en","type":"article","venue":"Genes to Cells","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Keio University","keywords":"Biology; Motility; Cyclophilin A; Biofilm; Cyclophilin; Microbiology; Cell biology; Bacteria; Biochemistry; Genetics; Molecular biology; Gene","score_opus":0.012456075421574678,"score_gpt":0.2114703261301069,"score_spread":0.19901425070853224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2438113208","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9921212,0.0019660331,0.003463031,0.00018409372,0.00001772922,0.000012820469,0.0004873404,0.00007590739,0.0016719083],"genre_scores_gemma":[0.99594265,0.00042728567,0.001071595,0.000043762437,0.000006582115,0.000011919682,0.00069397286,0.000015049996,0.001787118],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988866,0.000019141056,0.000005425213,0.000027587052,0.000040140912,0.000018892923],"domain_scores_gemma":[0.9999074,0.000010836973,0.000032071246,0.00000912844,0.00000967523,0.00003092512],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000057762645,0.00036142446,0.00020925727,0.00019790736,0.00020306517,0.00025364925,0.00012708423,0.00027061612,0.0012815392],"category_scores_gemma":[0.00012658015,0.00013493936,0.00019417667,0.00017742324,0.0001859059,0.000106257794,0.00024745573,0.0003250498,0.00046319154],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000034973917,0.000005066775,0.0002907829,0.00001374028,0.0000030959816,0.00007012421,0.000002866596,0.00001562559,0.999108,0.000037064776,0.000023955774,0.00039455833],"study_design_scores_gemma":[0.000009224747,0.00007956057,0.025119793,0.0000049460496,0.000013664168,0.0011608232,0.000019256468,0.0011708881,0.96918666,0.000054317716,0.003176492,0.0000043544337],"about_ca_topic_score_codex":0.00047268948,"about_ca_topic_score_gemma":0.00042232004,"teacher_disagreement_score":0.0012815392,"about_ca_system_score_codex":0.00027538964,"about_ca_system_score_gemma":0.000114873765,"threshold_uncertainty_score":0.0042871237},"labels":[],"label_agreement":null},{"id":"W2438374830","doi":"10.25011/cim.v39i3.26796","title":"Plasma EMMPRIN levels in acute myocardial infarction and stable coronary artery disease","year":2016,"lang":"en","type":"article","venue":"Clinical and investigative medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Myocardial infarction; Medicine; Internal medicine; Coronary artery disease; Cardiology; Logistic regression; Plasma levels; Plasma concentration; Disease","score_opus":0.09556675132158934,"score_gpt":0.3220286878611108,"score_spread":0.22646193653952143,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2438374830","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9980629,0.0013174893,0.00012554186,0.000028521603,0.000007383305,0.000005350374,0.000070617774,0.0000041060434,0.00037794953],"genre_scores_gemma":[0.9992539,0.00028614482,0.00012967068,0.00002220997,0.000029306677,0.000006389636,0.00012174917,9.148677e-7,0.00014956079],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9997433,0.00007968078,0.00003476099,0.00005937534,0.000047793128,0.00003505167],"domain_scores_gemma":[0.99926144,0.00022555582,0.00033404236,0.000026896649,0.00004357471,0.000108435685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031586963,0.00031312348,0.0003762494,0.0005364908,0.00023779053,0.00039570476,0.00014530771,0.00040297088,0.0016143604],"category_scores_gemma":[0.0012237962,0.00014037995,0.00023540501,0.00052518846,0.00021486457,0.00028773112,0.00034520138,0.00039422032,0.00021083561],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00091641577,0.00004977223,0.9940223,0.00003698021,0.00006479529,0.00027205615,0.000042790536,0.000029568539,0.0013054522,0.000026814969,0.00005012181,0.0031829583],"study_design_scores_gemma":[0.000013439077,0.00025294878,0.9982691,0.0000067188616,0.00003550148,0.00081758254,0.00005396212,0.00013716215,0.000222506,0.000042393018,0.00014645906,0.000002276807],"about_ca_topic_score_codex":0.00027104994,"about_ca_topic_score_gemma":0.00023037092,"teacher_disagreement_score":0.0016143604,"about_ca_system_score_codex":0.000109309534,"about_ca_system_score_gemma":0.0000826095,"threshold_uncertainty_score":0.005400598},"labels":[],"label_agreement":null},{"id":"W2465479990","doi":"10.1007/978-1-59745-030-0_12","title":"Characterization of Cardiac Gene Promoter Activity","year":2007,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Promoter; Gene; Biology; Heterologous; Reporter gene; Transcription factor; Gene expression; Transfection; Transcription (linguistics); Context (archaeology); Heterologous expression; Regulation of gene expression; Genetics; Cell biology; Molecular biology; Recombinant DNA","score_opus":0.01863919923403311,"score_gpt":0.36694940012049226,"score_spread":0.34831020088645914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2465479990","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.60753196,0.008028596,0.36506256,0.0005336042,0.00019513331,0.00060028984,0.008767553,0.00076241227,0.008517876],"genre_scores_gemma":[0.7090083,0.010159193,0.22776544,0.00036690888,0.00011541499,0.0012660264,0.036583,0.00084695825,0.013888714],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994677,0.00006710337,0.000060978524,0.00012966897,0.00018991972,0.00008466223],"domain_scores_gemma":[0.99882895,0.00041397932,0.00016100958,0.00015231046,0.00033779113,0.00010597147],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00077189173,0.00040130923,0.00044254298,0.00071568723,0.00022862415,0.00046610215,0.00046908113,0.00028414032,0.0014888644],"category_scores_gemma":[0.0011310654,0.0002428299,0.00047296332,0.0005644877,0.00035541845,0.000316775,0.00033178908,0.001255775,0.0010821739],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021399605,0.000009676497,0.00015704236,0.000045802546,0.0000027284782,0.00001772537,0.000024974262,0.000045320856,0.9977691,0.00016742824,0.000024379384,0.0017144502],"study_design_scores_gemma":[0.000007672454,0.00009135012,0.001872297,0.000021709333,0.00001445588,0.00015341322,0.000025623282,0.0007919598,0.99075794,0.00011041723,0.0061472976,0.0000059023646],"about_ca_topic_score_codex":0.00046205378,"about_ca_topic_score_gemma":0.0006770535,"teacher_disagreement_score":0.0014888644,"about_ca_system_score_codex":0.00027602314,"about_ca_system_score_gemma":0.00059091905,"threshold_uncertainty_score":0.004980743},"labels":[],"label_agreement":null},{"id":"W2469676477","doi":"10.1136/thoraxjnl-2015-207236","title":"Latrophilin receptors: novel bronchodilator targets in asthma","year":2016,"lang":"en","type":"article","venue":"Thorax","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Paul's Hospital; University of British Columbia; Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec; University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"National Heart, Lung, and Blood Institute; National Health and Medical Research Council; Medical Research Council; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs; Michael Smith Health Research BC","keywords":"Medicine; Ex vivo; Asthma; In vivo; Bronchodilator; In vitro; Airway; Receptor; Immunology; Contraction (grammar); Internal medicine; Biology; Anesthesia","score_opus":0.012867837649746442,"score_gpt":0.25466832085762847,"score_spread":0.24180048320788203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2469676477","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4395795,0.5325809,0.0076350295,0.006458222,0.00045669475,0.00017918824,0.0009244061,0.00036423732,0.01182183],"genre_scores_gemma":[0.77686805,0.20263696,0.00731782,0.0017254216,0.0005620393,0.00017662143,0.0014521051,0.000030787127,0.009230269],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999336,0.000014863278,0.0000033534532,0.000010763068,0.000016028454,0.000021450815],"domain_scores_gemma":[0.99995196,0.000009645166,0.000013433799,0.0000019410097,0.000007516142,0.000015445423],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024337157,0.00041894562,0.00044356482,0.00025858317,0.00011560573,0.0004139985,0.000313065,0.00051336724,0.0019472713],"category_scores_gemma":[0.00008920138,0.00009943489,0.00025349355,0.00015684546,0.00019784435,0.00026645197,0.0002113029,0.0005421013,0.0007147619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018517044,0.0003083919,0.0032166694,0.0013092839,0.0000993122,0.0014776019,0.00010205999,0.0011059121,0.84266466,0.0017747177,0.0042761294,0.1418135],"study_design_scores_gemma":[0.002094531,0.0141525585,0.09045009,0.00090811326,0.001085856,0.014802372,0.0007961744,0.009604753,0.51274633,0.0046112603,0.34860027,0.00014769634],"about_ca_topic_score_codex":0.00018279262,"about_ca_topic_score_gemma":0.00063414057,"teacher_disagreement_score":0.0019472713,"about_ca_system_score_codex":0.00030420988,"about_ca_system_score_gemma":0.00014808438,"threshold_uncertainty_score":0.006514311},"labels":[],"label_agreement":null},{"id":"W2486993525","doi":"10.1016/j.molimm.2016.07.009","title":"RCAN1 deficiency protects against Salmonella intestinal infection by modulating JNK activation","year":2016,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Natural Science Foundation of China","keywords":"Proinflammatory cytokine; Inflammation; Immunology; Biology; Salmonella infection; Gastrointestinal tract; Salmonella; Pathogen; Microbiology; Bacteria","score_opus":0.006905188712722389,"score_gpt":0.2226033758090586,"score_spread":0.2156981870963362,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2486993525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914586,0.0024066423,0.0018547125,0.00043986345,0.00014455312,0.000046355937,0.0011267716,0.0002569147,0.0022656024],"genre_scores_gemma":[0.9886634,0.0011243941,0.0024158072,0.00012207721,0.000027271439,0.000069621936,0.0009401683,0.00007419462,0.0065631415],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99973565,0.000043998658,0.00002442925,0.00005689328,0.000052045452,0.00008688552],"domain_scores_gemma":[0.9995863,0.000027783086,0.00014470537,0.000046714067,0.000042484637,0.00015197395],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023224863,0.00077288575,0.00038001803,0.0005770252,0.0002988096,0.0004653621,0.00068186055,0.0005599612,0.0032710277],"category_scores_gemma":[0.00018033106,0.00025580366,0.0003555347,0.00022437314,0.00047415635,0.00034065222,0.0002803002,0.0011760567,0.0010677696],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009157527,0.000091431764,0.00018687687,0.0000724399,0.00001372215,0.00007501831,0.000012225865,0.00008954693,0.9970667,0.0001566976,0.00013896612,0.0011807706],"study_design_scores_gemma":[0.000061686376,0.0002804675,0.00432664,0.000016972312,0.000039889674,0.0002632209,0.00005821947,0.00092765514,0.9905149,0.0001034538,0.003392953,0.000013990406],"about_ca_topic_score_codex":0.0010950878,"about_ca_topic_score_gemma":0.0019277995,"teacher_disagreement_score":0.0032710277,"about_ca_system_score_codex":0.0007355606,"about_ca_system_score_gemma":0.0004866957,"threshold_uncertainty_score":0.010942638},"labels":[],"label_agreement":null},{"id":"W2515802075","doi":"10.1016/j.sbi.2016.08.002","title":"Single versus dual-binding conformations in cellulosomal cohesin–dockerin complexes","year":2016,"lang":"en","type":"review","venue":"Current Opinion in Structural Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Fundação para a Ciência e a Tecnologia; Israel Science Foundation; German-Israeli Foundation for Scientific Research and Development; Branco Weiss Fellowship – Society in Science; Natural Science Foundation of Shanghai","keywords":"Cohesin; Cellulosome; Chemistry; Computational biology; Ligand (biochemistry); Biochemistry; Receptor; Cell biology; Biology; Cellulase; Enzyme; DNA; Clostridium thermocellum; Chromatin","score_opus":0.12192494785085406,"score_gpt":0.40288444254298916,"score_spread":0.2809594946921351,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2515802075","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0011346638,0.99659497,0.00048740048,0.0003638588,0.00023760415,0.0000040023283,0.000018236402,0.000016473205,0.001142795],"genre_scores_gemma":[0.006263459,0.9918024,0.00035533163,0.00023534428,0.00018266684,0.000007038872,0.00006377327,0.0000036496715,0.0010863949],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998542,0.000019807241,0.000017539442,0.00003502782,0.00004705761,0.0000263735],"domain_scores_gemma":[0.99989307,0.000036252866,0.000030058152,0.000004461223,0.000019394718,0.000016769496],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053859205,0.0005752973,0.0010988573,0.00054549857,0.00021887076,0.0013542842,0.00094870495,0.0011701811,0.0017707556],"category_scores_gemma":[0.00035779548,0.00028772317,0.00024535286,0.00080192037,0.00080214016,0.0014569084,0.00089943566,0.0012490781,0.001259891],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003031266,0.000047862126,0.00032286913,0.013276088,0.0001289226,0.0005970167,0.00011529917,0.0009472906,0.034856994,0.015188659,0.0185553,0.9156606],"study_design_scores_gemma":[0.000044021574,0.00012292077,0.0012454522,0.0016327222,0.000154524,0.0017386115,0.00017894882,0.0004844965,0.012573103,0.0061564897,0.9756114,0.00005718664],"about_ca_topic_score_codex":0.0005353785,"about_ca_topic_score_gemma":0.0010422837,"teacher_disagreement_score":0.0017707556,"about_ca_system_score_codex":0.00072294316,"about_ca_system_score_gemma":0.000605823,"threshold_uncertainty_score":0.0059238076},"labels":[],"label_agreement":null},{"id":"W2527238326","doi":"10.1371/journal.pone.0163678","title":"CD147 and Prostate Cancer: A Systematic Review and Meta-Analysis","year":2016,"lang":"en","type":"review","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Medicine; Prostate cancer; Meta-analysis; Odds ratio; Cochrane Library; Metastasis; Prostate; Oncology; Confidence interval; Cancer; Internal medicine","score_opus":0.13264459323319283,"score_gpt":0.3255512588895299,"score_spread":0.19290666565633707,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2527238326","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0030337048,0.9957767,0.00030966074,0.00014503351,0.00008796988,0.00015530606,0.00033915605,0.000013477385,0.00013909308],"genre_scores_gemma":[0.116911724,0.8781806,0.0018612598,0.00077118026,0.00030381032,0.0009579625,0.0007056509,0.000020835789,0.00028687477],"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99345547,0.002932919,0.0017983645,0.0007335242,0.0007829176,0.00029675337],"domain_scores_gemma":[0.9870337,0.009639676,0.0019063302,0.00034470062,0.0009074124,0.00016812437],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009107632,0.0026327455,0.017478202,0.006243472,0.0007162665,0.0028671029,0.0020991336,0.002169479,0.0038990483],"category_scores_gemma":[0.022479728,0.0013521095,0.032866288,0.007907116,0.0006447591,0.0015372772,0.0014790293,0.0016520229,0.0002767863],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014655457,0.000035203717,0.005515831,0.47656417,0.5023482,0.0001910886,0.00009354448,0.000566078,0.00021438433,0.00014857789,0.00078833976,0.012069049],"study_design_scores_gemma":[0.00034026144,0.0001609787,0.0037946603,0.027245993,0.9662368,0.00014266153,0.000039366398,0.0001767572,0.00007649205,0.00016281012,0.001600609,0.000022639317],"about_ca_topic_score_codex":0.0064532706,"about_ca_topic_score_gemma":0.015365768,"teacher_disagreement_score":0.017478202,"about_ca_system_score_codex":0.0021747944,"about_ca_system_score_gemma":0.0035101923,"threshold_uncertainty_score":0.048166335},"labels":[],"label_agreement":null},{"id":"W2531259928","doi":"10.1371/journal.pone.0163802","title":"Evaluating Soluble EMMPRIN as a Marker of Disease Activity in Multiple Sclerosis: Studies of Serum and Cerebrospinal Fluid","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital; McGill University; Hotchkiss Brain Institute; Université de Montréal; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Cerebrospinal fluid; Multiple sclerosis; Medicine; Matrix metalloproteinase; Metalloproteinase; Experimental autoimmune encephalomyelitis; Immunology; Encephalomyelitis; Basigin; Pathology; Extracellular matrix; Disease; Internal medicine; Biology","score_opus":0.16634225605723915,"score_gpt":0.31720963675399494,"score_spread":0.1508673806967558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2531259928","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.995118,0.0027141646,0.001458969,0.000026340123,0.000013751765,0.000022104883,0.00014256348,0.000028877725,0.00047509518],"genre_scores_gemma":[0.9968617,0.00066440925,0.0018670799,0.000024827146,0.000023797515,0.000025499692,0.00016779955,0.000004666298,0.0003602364],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.999522,0.00012770089,0.000050249044,0.000108295484,0.00015483642,0.00003693867],"domain_scores_gemma":[0.99955755,0.00009635374,0.00015124319,0.000025716528,0.00007986756,0.00008928712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006188358,0.00038458858,0.00039056924,0.001657452,0.00016444476,0.00042061132,0.00014058048,0.00048193356,0.0003831144],"category_scores_gemma":[0.0009233398,0.000118800315,0.00012827333,0.0007391178,0.000356063,0.00025130154,0.00022192766,0.00030428008,0.00015026779],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003461052,0.0002871044,0.24719538,0.0003819939,0.00018371841,0.0011833264,0.00042281236,0.00020290988,0.72043365,0.0001186104,0.00013082019,0.025998693],"study_design_scores_gemma":[0.00004980557,0.0035397443,0.74250805,0.000047453796,0.0002464794,0.0063718553,0.00031851025,0.00257044,0.24200249,0.00020566295,0.0021139972,0.000025489702],"about_ca_topic_score_codex":0.0004486822,"about_ca_topic_score_gemma":0.00037290563,"teacher_disagreement_score":0.001657452,"about_ca_system_score_codex":0.00015453494,"about_ca_system_score_gemma":0.0001372287,"threshold_uncertainty_score":0.0032727122},"labels":[],"label_agreement":null},{"id":"W2563225587","doi":"10.1016/j.tcb.2016.11.009","title":"RGMs: Structural Insights, Molecular Regulation, and Downstream Signaling","year":2016,"lang":"en","type":"review","venue":"Trends in Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":121,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Krembil Foundation","funders":"Medical Research Council; Cancer Research UK","keywords":"Biology; Downstream (manufacturing); Cell biology; Computational biology","score_opus":0.021953236089937135,"score_gpt":0.3121305773530622,"score_spread":0.29017734126312505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2563225587","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00038059108,0.99704945,0.0004917346,0.0005084725,0.00030930844,0.000004854998,0.00004144481,0.000029262526,0.001184868],"genre_scores_gemma":[0.0021884718,0.99560994,0.00039114576,0.00028126055,0.00023130656,0.0000070043443,0.00007953173,0.0000042961615,0.0012070978],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99980253,0.000020381138,0.000019806253,0.00003781332,0.000076972436,0.000042504686],"domain_scores_gemma":[0.99986064,0.000036038426,0.000032095875,0.000009069633,0.000038452552,0.000023631646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00068135647,0.0013517058,0.0013253329,0.0015237167,0.0003113731,0.0016727081,0.0014954603,0.0015185002,0.0024368567],"category_scores_gemma":[0.0004944811,0.00039681952,0.0004963382,0.0017756501,0.0011690597,0.0016861968,0.0011523212,0.0026170784,0.0028299247],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019591875,0.00006378446,0.00026390867,0.008721442,0.000094819836,0.0003915239,0.00008519414,0.0009207682,0.020548398,0.022800868,0.040498815,0.90541446],"study_design_scores_gemma":[0.00002077376,0.000051595274,0.0005507137,0.00086237444,0.00007748161,0.0010594516,0.000050762435,0.000198527,0.0041964413,0.005491584,0.9874127,0.000027573486],"about_ca_topic_score_codex":0.0008397735,"about_ca_topic_score_gemma":0.0012001102,"teacher_disagreement_score":0.0024368567,"about_ca_system_score_codex":0.0010069794,"about_ca_system_score_gemma":0.0010700623,"threshold_uncertainty_score":0.008152068},"labels":[],"label_agreement":null},{"id":"W2567289032","doi":"10.1158/1538-7445.am2015-2260","title":"Abstract 2260: Defining molecular mechanisms linking Endophilin A2 to metastasis in human breast cancer models","year":2015,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Invadopodia; Cancer research; Metastasis; Breast cancer; Internalization; Triple-negative breast cancer; Cancer; Estrogen receptor; Epithelial–mesenchymal transition; Extracellular matrix; Biology; Pathology; Medicine; Receptor; Internal medicine; Cell biology","score_opus":0.12367040410652676,"score_gpt":0.41318513727047984,"score_spread":0.2895147331639531,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2567289032","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9824728,0.0025494848,0.008411821,0.00022944147,0.00005699753,0.000226253,0.0016589379,0.000117534546,0.004276626],"genre_scores_gemma":[0.98102957,0.0017147001,0.006412089,0.00013236013,0.000027497634,0.00029953412,0.00260189,0.000029160743,0.0077532395],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989605,0.000024324734,0.0000075775656,0.000018454171,0.00003097964,0.000022488808],"domain_scores_gemma":[0.9999517,0.000007730207,0.000009979951,0.0000066126963,0.000007076616,0.000016879605],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019580123,0.00040058032,0.00021904778,0.00039176605,0.0001734659,0.000276728,0.00023460196,0.0002758929,0.0017575986],"category_scores_gemma":[0.00007419062,0.00013979115,0.00028728432,0.00015866056,0.00017175864,0.00019717393,0.000176345,0.00045938054,0.00056318636],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018443374,0.0000887272,0.00016801743,0.000038992475,0.0000055957007,0.00005219984,0.0000067037586,0.00011964912,0.998018,0.00025373866,0.00009755088,0.0009663877],"study_design_scores_gemma":[0.00006448683,0.0012266865,0.007814062,0.000010817235,0.00002705724,0.00048718476,0.000026969468,0.003775979,0.9814819,0.00018460173,0.0048925932,0.000007659143],"about_ca_topic_score_codex":0.0008613397,"about_ca_topic_score_gemma":0.0009525796,"teacher_disagreement_score":0.0017575986,"about_ca_system_score_codex":0.00033853538,"about_ca_system_score_gemma":0.0002283662,"threshold_uncertainty_score":0.00587976},"labels":[],"label_agreement":null},{"id":"W2572774001","doi":"10.1038/srep39550","title":"Soybean cyclophilin GmCYP1 interacts with an isoflavonoid regulator GmMYB176","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Agriculture and Agri-Food Canada; Western University","funders":"","keywords":"Isoflavonoid; Cyclophilin; Cytoplasm; Biology; Biochemistry; Cell biology; Peptidylprolyl isomerase; Isomerase; Abiotic stress; Flavonoid; Gene","score_opus":0.013119659635096943,"score_gpt":0.2687688228676104,"score_spread":0.25564916323251347,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2572774001","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9967553,0.0007078524,0.0007893962,0.000101205886,0.000013347352,0.00000832375,0.0004988003,0.000082071805,0.0010436903],"genre_scores_gemma":[0.9946567,0.00028128806,0.0009195232,0.00009052167,0.00000916009,0.000011693039,0.001954628,0.00002458864,0.0020519265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992883,0.000008567288,0.000003287497,0.000026535527,0.00001698455,0.000015849168],"domain_scores_gemma":[0.99994373,0.00000808624,0.000019464891,0.000005537519,0.0000048268757,0.000018400155],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006151583,0.00030125846,0.00020586603,0.00015712343,0.0001880924,0.0001516654,0.00012655686,0.00020142528,0.0015663079],"category_scores_gemma":[0.00008526296,0.00013149466,0.00028326613,0.00013750744,0.00010832192,0.000106185274,0.0002448509,0.0002332637,0.0007044338],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004850393,0.0000042460824,0.00045714455,0.00001546345,0.0000023123405,0.000059856102,0.000005263754,0.000018670422,0.9989905,0.000015771853,0.000057196034,0.0003251703],"study_design_scores_gemma":[0.00003433982,0.00014688724,0.114720955,0.000010333166,0.000025569369,0.0011438557,0.000058519043,0.0025550928,0.87669915,0.000052357074,0.004542892,0.000009991036],"about_ca_topic_score_codex":0.0011510267,"about_ca_topic_score_gemma":0.0017989101,"teacher_disagreement_score":0.0015663079,"about_ca_system_score_codex":0.00043149677,"about_ca_system_score_gemma":0.00013881762,"threshold_uncertainty_score":0.0052398443},"labels":[],"label_agreement":null},{"id":"W2581662090","doi":"10.1101/096271","title":"Regulation of eIF4F complex by the peptidyl prolyl isomerase FKBP7 in taxane-resistant prostate cancer","year":2016,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cabazitaxel; Prostate cancer; Docetaxel; Cancer research; Gene silencing; Taxane; Cancer; Biology; Medicine; Internal medicine; Breast cancer; Androgen deprivation therapy; Gene","score_opus":0.01288314540159897,"score_gpt":0.2352141927640701,"score_spread":0.22233104736247114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2581662090","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99332184,0.0026455936,0.0015191981,0.00022464275,0.000062416024,0.000015717318,0.00075210206,0.00012758224,0.0013309193],"genre_scores_gemma":[0.99406576,0.00077001733,0.0011166916,0.000047600268,0.000006936139,0.000016606135,0.00079318124,0.000022926673,0.003160217],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999385,0.000007934562,0.000004223574,0.000012125828,0.000023267348,0.000014035306],"domain_scores_gemma":[0.99997294,0.000003723962,0.000007230747,0.0000028100828,0.000005014954,0.00000820078],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000072621486,0.00016694526,0.00020787894,0.00024311992,0.0002055971,0.00023198484,0.00011401274,0.00020209089,0.0014566843],"category_scores_gemma":[0.00007174906,0.00009955178,0.00017976265,0.0001373942,0.00011485777,0.00007656113,0.00010067569,0.0003192678,0.0003753756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013487317,0.000014026792,0.00038456987,0.0000298387,0.000006655584,0.000071210896,0.0000075748426,0.000110404835,0.997792,0.000059365117,0.00017364664,0.0012158339],"study_design_scores_gemma":[0.000021139771,0.00010708024,0.011248207,0.000004038407,0.000017199302,0.0002904379,0.000024223904,0.0021805926,0.9825853,0.00004801047,0.003468892,0.00000482901],"about_ca_topic_score_codex":0.0014550172,"about_ca_topic_score_gemma":0.0014992829,"teacher_disagreement_score":0.0014566843,"about_ca_system_score_codex":0.00042545752,"about_ca_system_score_gemma":0.00015336061,"threshold_uncertainty_score":0.004873097},"labels":[],"label_agreement":null},{"id":"W2586915005","doi":"10.1093/ndt/gfw178.43","title":"SP684A CALCINEURIN INHIBITOR WITH AN IMPROVED SIDE EFFECT PROFILE?","year":2016,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Medicine; Calcineurin; Pharmacology; Internal medicine; Transplantation","score_opus":0.005358435664602016,"score_gpt":0.23037128597052522,"score_spread":0.22501285030592322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2586915005","genre_codex":"empirical","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.51191735,0.3965796,0.007957045,0.020295795,0.0034257665,0.0005768829,0.0021382503,0.0008174172,0.056291964],"genre_scores_gemma":[0.88521105,0.0683781,0.008210624,0.011104134,0.0023331845,0.00032591325,0.0024268753,0.00009343041,0.021916714],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997149,0.00007803538,0.000033144384,0.000054048884,0.00007851147,0.000041348736],"domain_scores_gemma":[0.9996828,0.00006325721,0.00009256395,0.00001992604,0.00006594083,0.00007555786],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00063499965,0.000326116,0.00069613574,0.00022624448,0.00012726213,0.0004988674,0.0004078833,0.0006958499,0.011638527],"category_scores_gemma":[0.00049983984,0.00006917993,0.00060788647,0.00030075165,0.00019062679,0.00038440878,0.00017699863,0.0011835553,0.0027097333],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.012968318,0.0016669667,0.0067652366,0.0022470853,0.0005309214,0.0017081788,0.00006321444,0.000551165,0.040898588,0.002401609,0.025879368,0.9043194],"study_design_scores_gemma":[0.016889514,0.081211254,0.06717267,0.0019288135,0.0024175155,0.050615236,0.00026194798,0.0059033628,0.09072858,0.004669452,0.67800844,0.00019318434],"about_ca_topic_score_codex":0.0001907195,"about_ca_topic_score_gemma":0.0005960231,"teacher_disagreement_score":0.011638527,"about_ca_system_score_codex":0.00032878137,"about_ca_system_score_gemma":0.000332429,"threshold_uncertainty_score":0.038934708},"labels":[],"label_agreement":null},{"id":"W2588151809","doi":"10.1093/ndt/gfw178.30","title":"SP671CALCINEURIN INHIBITION WITHOUT THERAPEUTIC DRUG MONITORING?","year":2016,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Medicine; Therapeutic drug monitoring; Drug; Pharmacology; Intensive care medicine","score_opus":0.011050522203400864,"score_gpt":0.2530823561921424,"score_spread":0.24203183398874156,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2588151809","genre_codex":"empirical","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.40163845,0.32866952,0.07304466,0.053440064,0.0040515075,0.00060559297,0.0015198609,0.0022959558,0.13473435],"genre_scores_gemma":[0.9113064,0.036622707,0.023721788,0.00818249,0.0020396188,0.0002021474,0.00086248695,0.00013849851,0.016923858],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99939454,0.00014211872,0.000055953264,0.00011127656,0.00024305475,0.000052980737],"domain_scores_gemma":[0.99947673,0.0001522416,0.00016148949,0.000049690563,0.00010505466,0.00005487889],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008928002,0.00036354485,0.00068729353,0.00026047957,0.00017125087,0.000720792,0.00049050216,0.00076141657,0.0045376606],"category_scores_gemma":[0.0013234031,0.000100892794,0.00028016075,0.00030975766,0.00040915128,0.00061586354,0.00026362285,0.001224466,0.0016249454],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00458888,0.000501151,0.008484509,0.0009975304,0.00017761384,0.0017353971,0.00006939821,0.00090444036,0.05724429,0.008235063,0.021183794,0.8958779],"study_design_scores_gemma":[0.0014634748,0.0087947035,0.026661031,0.0010195377,0.0006358889,0.036366493,0.0001983215,0.009687016,0.31693193,0.017326606,0.58079356,0.000121537276],"about_ca_topic_score_codex":0.00024855335,"about_ca_topic_score_gemma":0.0005469613,"teacher_disagreement_score":0.0045376606,"about_ca_system_score_codex":0.0006057676,"about_ca_system_score_gemma":0.000467568,"threshold_uncertainty_score":0.015180051},"labels":[],"label_agreement":null},{"id":"W2594520384","doi":"10.71781/29071","title":"Élucidation des mécanismes moléculaires par lesquels ARF6 contrôle la fonction des récepteurs couplés aux protéines G","year":2006,"lang":"fr","type":"dissertation","venue":"Papyrus : Institutional Repository (Université de Montréal)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; McGill University; Heart and Stroke Foundation of Canada","keywords":"Chemistry","score_opus":0.00684777818999154,"score_gpt":0.19517410358393564,"score_spread":0.1883263253939441,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2594520384","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95723253,0.006971702,0.017016312,0.0023301512,0.00015954794,0.0000629693,0.0012597692,0.00044293518,0.01452402],"genre_scores_gemma":[0.96054846,0.0047021066,0.00867211,0.00021296596,0.000049006696,0.000041913372,0.001319799,0.00008001409,0.024373533],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987876,0.000012867175,0.000004409887,0.000026434027,0.00003411155,0.000043386768],"domain_scores_gemma":[0.999907,0.000027744547,0.0000135005575,0.000013458893,0.00001886842,0.000019472995],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036392975,0.00046040685,0.00032168577,0.00029677962,0.00075193314,0.00082757196,0.00058538397,0.0005692656,0.0036935424],"category_scores_gemma":[0.00036490822,0.0002495414,0.00043698496,0.00020579108,0.00045337217,0.00066668325,0.000236931,0.0008561197,0.00084907777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002494715,0.000025184558,0.0009481051,0.000052796873,0.0000072652533,0.00013446098,0.00008436546,0.00027029848,0.98746186,0.0027875279,0.00034619623,0.007632449],"study_design_scores_gemma":[0.000023919183,0.00006743412,0.010102235,0.000009442657,0.00001690901,0.00030585998,0.00011694152,0.0017371017,0.9763315,0.0007250743,0.010552914,0.0000106400685],"about_ca_topic_score_codex":0.017721137,"about_ca_topic_score_gemma":0.015339831,"teacher_disagreement_score":0.017721137,"about_ca_system_score_codex":0.0010870508,"about_ca_system_score_gemma":0.0010297475,"threshold_uncertainty_score":0.035236},"labels":[],"label_agreement":null},{"id":"W2599152940","doi":"10.1093/hmg/ddx109","title":"Misregulation of calcium-handling proteins promotes hyperactivation of calcineurin–NFAT signaling in skeletal muscle of DM1 mice","year":2017,"lang":"en","type":"article","venue":"Human Molecular Genetics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Biology; Hyperactivation; NFAT; Skeletal muscle; Calcineurin; Endocrinology; Cell biology; Internal medicine; Calsequestrin; SERCA; Calcium signaling; Signal transduction; Endoplasmic reticulum; Ryanodine receptor; Biochemistry; ATPase; Transcription factor","score_opus":0.029669015046296956,"score_gpt":0.303467067642496,"score_spread":0.27379805259619905,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2599152940","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9962612,0.0011852569,0.00082201534,0.00014246657,0.000030256146,0.000024938634,0.00068843365,0.000105675856,0.000739836],"genre_scores_gemma":[0.98831636,0.0015118239,0.0021479991,0.00015271018,0.00002596411,0.00015080876,0.0012334445,0.00010277323,0.006358139],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99957603,0.000058334776,0.000055679997,0.00014001568,0.00009242837,0.00007755479],"domain_scores_gemma":[0.99947613,0.000039869818,0.0002080857,0.000027254247,0.000026249876,0.00022253934],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024200269,0.00095669675,0.00052886235,0.0010360457,0.00032698427,0.00038694387,0.00040581624,0.00065784325,0.0025264516],"category_scores_gemma":[0.00017109224,0.00043470776,0.0004704834,0.00032381137,0.00043322844,0.0002721899,0.0003625318,0.001174834,0.00045908417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00028408106,0.00004928032,0.00030652864,0.000039158884,0.0000090051435,0.0000703386,0.000025097179,0.000025080717,0.99872416,0.000048382077,0.000021137532,0.00039770314],"study_design_scores_gemma":[0.00014112327,0.00111472,0.039418954,0.000050786257,0.000082204366,0.00078213663,0.00013013948,0.0010678103,0.9543682,0.00012193789,0.0027011663,0.000020822672],"about_ca_topic_score_codex":0.0010033342,"about_ca_topic_score_gemma":0.0015513572,"teacher_disagreement_score":0.0025264516,"about_ca_system_score_codex":0.00056525547,"about_ca_system_score_gemma":0.00022843391,"threshold_uncertainty_score":0.008451879},"labels":[],"label_agreement":null},{"id":"W2601643262","doi":"","title":"Investigation of the effect mutations of CaM have upon in vitro and ex vivo function","year":2010,"lang":"en","type":"dissertation","venue":"UWSpace (University of Waterloo)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of Waterloo","keywords":"Ex vivo; In vitro; In vivo; Function (biology); Biology; Computational biology; Genetics","score_opus":0.005408249114234969,"score_gpt":0.18870291655157634,"score_spread":0.18329466743734138,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2601643262","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9945827,0.00074148213,0.0027854599,0.00009458901,0.000044914847,0.000014926372,0.00025527226,0.0000274577,0.0014532418],"genre_scores_gemma":[0.99389726,0.0005774223,0.0020255642,0.00006252596,0.000010814697,0.000025456493,0.00051360554,0.000038588343,0.0028487267],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983096,0.00004805794,0.000020272619,0.000030745643,0.00004213113,0.000027890248],"domain_scores_gemma":[0.9997465,0.00011047814,0.000046289893,0.000038829214,0.000031715455,0.000026253923],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00029640523,0.00025854175,0.00015952981,0.00007993541,0.00016570649,0.00030151475,0.00034151666,0.00030238443,0.0014482368],"category_scores_gemma":[0.00026348114,0.00011211248,0.0001478255,0.00008219155,0.00022785789,0.00030010578,0.00012747954,0.00058356376,0.0003239364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006068783,0.000037629463,0.00010782405,0.000018777402,0.000002787854,0.000032223164,0.00001647653,0.0000499859,0.9990802,0.000091336275,0.000025586265,0.00047658395],"study_design_scores_gemma":[0.000006953905,0.0001283368,0.0014633395,0.000002809152,0.0000069057337,0.00010896333,0.000018202636,0.0005564676,0.99652064,0.000017614071,0.0011673553,0.0000023702064],"about_ca_topic_score_codex":0.00092339475,"about_ca_topic_score_gemma":0.00093292346,"teacher_disagreement_score":0.0014482368,"about_ca_system_score_codex":0.00039360224,"about_ca_system_score_gemma":0.000112747155,"threshold_uncertainty_score":0.0048448443},"labels":[],"label_agreement":null},{"id":"W2604211359","doi":"10.3389/fpls.2017.00502","title":"The Kinase Activity of Calcineurin B-like Interacting Protein Kinase 26 (CIPK26) Influences Its Own Stability and that of the ABA-regulated Ubiquitin Ligase, Keep on Going (KEG)","year":2017,"lang":"en","type":"article","venue":"Frontiers in Plant Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Ubiquitin ligase; Kinase; Cell biology; Ubiquitin; Chemistry; Protein kinase A; Biochemistry; Calcineurin; DNA ligase; Enzyme; Biology; Gene","score_opus":0.02192693687706847,"score_gpt":0.26507091549546224,"score_spread":0.24314397861839376,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2604211359","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97949344,0.008856085,0.005780471,0.00019080694,0.00007148869,0.000027276434,0.00064267375,0.00016873618,0.004769112],"genre_scores_gemma":[0.9933375,0.0017314547,0.001672844,0.000039821974,0.000014696606,0.0000111183745,0.0005849857,0.000032173062,0.00257543],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986064,0.000009347643,0.0000084054,0.000059675534,0.000027073309,0.000034842706],"domain_scores_gemma":[0.9998242,0.000022011614,0.000061951905,0.0000208337,0.000019776317,0.000051152776],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014656161,0.00045463542,0.00022578998,0.00029976235,0.00032200644,0.00057359174,0.0002509747,0.00027654073,0.0018773959],"category_scores_gemma":[0.0001684864,0.00013838083,0.00031668166,0.00020476016,0.000428385,0.0004055208,0.0002937585,0.0005097057,0.0006607217],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011901958,0.000016109361,0.0006995779,0.00005614002,0.0000061632613,0.00008209512,0.000010314475,0.00010767957,0.99689204,0.00022847825,0.00006724273,0.0017151067],"study_design_scores_gemma":[0.0000116742,0.00008859493,0.015227255,0.000006540731,0.000018068804,0.00060691463,0.000034200948,0.0011924047,0.97773564,0.00017200719,0.0048910347,0.000015693764],"about_ca_topic_score_codex":0.00059009925,"about_ca_topic_score_gemma":0.00075193774,"teacher_disagreement_score":0.0018773959,"about_ca_system_score_codex":0.00046794786,"about_ca_system_score_gemma":0.00024514546,"threshold_uncertainty_score":0.0062805414},"labels":[],"label_agreement":null},{"id":"W2606694411","doi":"10.1016/j.stemcr.2017.03.018","title":"Calreticulin Is Required for TGF-β-Induced Epithelial-to-Mesenchymal Transition during Cardiogenesis in Mouse Embryonic Stem Cells","year":2017,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; University of Alberta","keywords":"Biology; Calreticulin; Embryonic stem cell; Cell biology; Mesenchymal stem cell; Stem cell; Epithelial–mesenchymal transition; Transforming growth factor; Transition (genetics); Endoplasmic reticulum; Gene; Genetics","score_opus":0.018590811869319532,"score_gpt":0.25129901313871467,"score_spread":0.23270820126939512,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2606694411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934515,0.001429881,0.0030000205,0.000092463415,0.000022079295,0.00002493451,0.0006074022,0.00011634899,0.0012553977],"genre_scores_gemma":[0.9932458,0.0007428233,0.002094752,0.00005366591,0.000007691323,0.000041841395,0.0011892882,0.000056909175,0.0025672782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984014,0.000018693412,0.0000252856,0.000029728044,0.000054952798,0.000031149848],"domain_scores_gemma":[0.99971586,0.00002980485,0.00011324158,0.000033143468,0.00002579978,0.00008220567],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001332015,0.0002830701,0.00026327194,0.0002916922,0.00017062189,0.00036059952,0.00019493446,0.00022647971,0.0009824974],"category_scores_gemma":[0.00015033499,0.00027416542,0.0002260976,0.00017056789,0.00024496182,0.00024028635,0.0003119174,0.00061062403,0.0007116259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003350209,0.000005117116,0.00017260051,0.000009317845,0.0000014371568,0.00004267984,0.000006489841,0.000014217925,0.9994136,0.000042924305,0.000008172513,0.00024993307],"study_design_scores_gemma":[0.000015184111,0.00006480374,0.01393233,0.000006922676,0.000010641888,0.0003111137,0.00002575073,0.00045077337,0.98331946,0.000049929335,0.0018097103,0.0000032415837],"about_ca_topic_score_codex":0.0006177091,"about_ca_topic_score_gemma":0.0011554742,"teacher_disagreement_score":0.0009824974,"about_ca_system_score_codex":0.00037224375,"about_ca_system_score_gemma":0.00025138995,"threshold_uncertainty_score":0.003286779},"labels":[],"label_agreement":null},{"id":"W2607053400","doi":"10.1007/s00441-017-2610-3","title":"Immunohistochemical mapping and transcript expression of the GPA2/GPB5 receptor in tissues of the adult mosquito, Aedes aegypti","year":2017,"lang":"en","type":"article","venue":"Cell and Tissue Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aedes aegypti; Immunohistochemistry; Biology; Expression (computer science); Aedes; Molecular biology; Computational biology; Pathology; Virology; Computer science; Medicine; Immunology; Dengue fever; Ecology","score_opus":0.036522784276217524,"score_gpt":0.3281885865099837,"score_spread":0.2916658022337662,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2607053400","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98921156,0.001421039,0.00450515,0.00009734126,0.000016756263,0.000019422521,0.0013354698,0.000041965894,0.003351307],"genre_scores_gemma":[0.9819395,0.0013555635,0.0056470963,0.00011144734,0.000016203336,0.000038168822,0.0024902483,0.000030477686,0.008371336],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995196,0.000004343418,0.0000029666069,0.000015544694,0.000008630005,0.0000165462],"domain_scores_gemma":[0.99996483,0.000004582153,0.000009352691,0.000003426432,0.000006678384,0.000011147876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006452153,0.00015721095,0.00009313492,0.00032062305,0.00021682441,0.00022043563,0.00010147605,0.00015631097,0.0016227507],"category_scores_gemma":[0.000054925822,0.00012695463,0.00015514441,0.00017100268,0.0001728858,0.0002824792,0.00015523854,0.00028738898,0.0004003923],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000046198857,0.0000036664803,0.0005468685,0.000015964086,0.0000035404207,0.000042264262,0.00001717289,0.00001611294,0.99851805,0.00013481862,0.000032107913,0.000623304],"study_design_scores_gemma":[0.00003356344,0.00049110985,0.27561572,0.000026315422,0.000087468376,0.0021866702,0.00081544084,0.0018152257,0.709191,0.0003786742,0.009342693,0.000015982525],"about_ca_topic_score_codex":0.0012435018,"about_ca_topic_score_gemma":0.0024815344,"teacher_disagreement_score":0.0016227507,"about_ca_system_score_codex":0.00019404489,"about_ca_system_score_gemma":0.00012180026,"threshold_uncertainty_score":0.005428612},"labels":[],"label_agreement":null},{"id":"W2613767724","doi":"10.1016/j.ceb.2017.03.011","title":"Plasma membrane repair: the adaptable cell life-insurance","year":2017,"lang":"en","type":"review","venue":"Current Opinion in Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":97,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Labex CelTisPhyBio; Institut Curie; Commissariat à l'Énergie Atomique et aux Énergies Alternatives; Centre National de la Recherche Scientifique; Ligue Contre le Cancer; Agence Nationale de la Recherche; Fondation pour la Recherche Médicale; European Research Council; Institut national de la recherche scientifique","keywords":"Extracellular; Biology; Cell biology; Membrane; Homeostasis; Cell; Cell membrane; Calcium; Biophysics; Biochemistry; Chemistry","score_opus":0.14213723703647024,"score_gpt":0.389109715098149,"score_spread":0.24697247806167877,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2613767724","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021657634,0.9945602,0.0008341505,0.0020270166,0.00075909356,0.0000047742474,0.000034296158,0.000020363761,0.0015435164],"genre_scores_gemma":[0.002788676,0.9941744,0.00031876168,0.0009192316,0.0006373395,0.0000091754555,0.0000512452,0.0000040455657,0.00109726],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99968445,0.000052466476,0.0000279755,0.00007054751,0.000104023005,0.000060509254],"domain_scores_gemma":[0.9996494,0.00014099033,0.000056852306,0.000018461064,0.00008389183,0.000050394636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009119249,0.00087156123,0.0017242646,0.0011745325,0.00040630015,0.002284238,0.0015649997,0.0026709882,0.0034960716],"category_scores_gemma":[0.0008759792,0.0002902931,0.00043773587,0.0012037227,0.0017889896,0.0027925118,0.0016125913,0.003320199,0.0022602451],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013031017,0.000044891545,0.00022019085,0.008805598,0.00008893444,0.00041021733,0.000086302265,0.0007114894,0.005958799,0.04982664,0.05792693,0.8757896],"study_design_scores_gemma":[0.000015587684,0.000043096803,0.00039357433,0.0013273485,0.000060246482,0.000995792,0.00008911234,0.00023125691,0.0012801285,0.016589398,0.97894776,0.000026684796],"about_ca_topic_score_codex":0.0005220867,"about_ca_topic_score_gemma":0.0007938993,"teacher_disagreement_score":0.0034960716,"about_ca_system_score_codex":0.0011553405,"about_ca_system_score_gemma":0.0012423445,"threshold_uncertainty_score":0.011695564},"labels":[],"label_agreement":null},{"id":"W2614215464","doi":"10.1139/cjpp-2016-0449","title":"HDAC2 is required by the physiological concentration of glucocorticoid to inhibit inflammation in cardiac fibroblasts","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"Xanthine oxidase; Inflammation; Proinflammatory cytokine; Glucocorticoid; Lipopolysaccharide; Endogeny; Endocrinology; Internal medicine; Xanthine; Downregulation and upregulation; Hydrocortisone; Oxidative stress; Chemistry; Pharmacology; Medicine; Enzyme; Biochemistry","score_opus":0.0153449959753102,"score_gpt":0.280273084958444,"score_spread":0.2649280889831338,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2614215464","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98724514,0.0066373004,0.0027540768,0.00023838175,0.0001531147,0.00002984779,0.0006569661,0.00006971108,0.0022153207],"genre_scores_gemma":[0.99554956,0.0012879152,0.0009156897,0.000074778836,0.000025080062,0.000029951167,0.0004679611,0.0000107194155,0.0016383565],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986005,0.00001713246,0.000018165889,0.000036587775,0.000030339244,0.000037672777],"domain_scores_gemma":[0.99993217,0.0000075905837,0.000018100687,0.000010851773,0.000010256228,0.000021016516],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011092584,0.00028351633,0.00033515773,0.00011151817,0.00021546795,0.00031297188,0.00014383008,0.00021309796,0.001343367],"category_scores_gemma":[0.00010538294,0.00014291426,0.00032697213,0.000100349236,0.00025142208,0.0001866914,0.00017563601,0.00042210252,0.00027956575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013985911,0.00001788857,0.0003492206,0.000046219757,0.000006217493,0.00006990825,0.000014696154,0.00002135156,0.998546,0.000060321436,0.000048901387,0.000679427],"study_design_scores_gemma":[0.00005853306,0.0002812882,0.019357447,0.0000119491215,0.000033727854,0.00038005423,0.00010083212,0.0006492834,0.9745753,0.000073291965,0.0044688056,0.000009541901],"about_ca_topic_score_codex":0.0011206708,"about_ca_topic_score_gemma":0.0019447485,"teacher_disagreement_score":0.001343367,"about_ca_system_score_codex":0.00028088555,"about_ca_system_score_gemma":0.00023432655,"threshold_uncertainty_score":0.0044940114},"labels":[],"label_agreement":null},{"id":"W2614539848","doi":"10.1016/j.molimm.2017.05.006","title":"Scaffold protein JLP mediates TCR-initiated CD4 + T cell activation and CD154 expression","year":2017,"lang":"en","type":"article","venue":"Molecular Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"CD154; Cell biology; T-cell receptor; T cell; CD40; Signal transduction; Biology; Scaffold protein; IL-2 receptor; Immune system; Chemistry; Immunology; Cytotoxic T cell; In vitro; Biochemistry","score_opus":0.01337365954829244,"score_gpt":0.2485065709658315,"score_spread":0.23513291141753906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2614539848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99098676,0.0010010834,0.0047113267,0.0002595807,0.000058805013,0.000019803028,0.0003093853,0.00016598609,0.0024872427],"genre_scores_gemma":[0.99518025,0.0002416647,0.0015508009,0.000041968848,0.000024371311,0.000021027303,0.0005431711,0.00003736847,0.0023593795],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99970466,0.000038817667,0.000016877962,0.000054040498,0.000060868104,0.0001246575],"domain_scores_gemma":[0.9997813,0.000043421365,0.00004586569,0.000027705733,0.000030422152,0.00007127173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023865364,0.000514364,0.00025167776,0.0003620148,0.00045056507,0.0006720853,0.00025401614,0.00041843872,0.002651725],"category_scores_gemma":[0.0002797244,0.00021738664,0.00033842874,0.0001691188,0.00034197103,0.00044363525,0.0007809552,0.0009278542,0.0013412954],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002114645,0.000017640159,0.00017770217,0.000026113688,0.00000292478,0.00012706817,0.000017642062,0.00004439352,0.99827075,0.00026926972,0.00008331974,0.0007515917],"study_design_scores_gemma":[0.000046550867,0.00010190672,0.00414569,0.0000063985694,0.000011381907,0.00029030495,0.00007838798,0.00097419764,0.99180204,0.00020679877,0.0023309526,0.000005405826],"about_ca_topic_score_codex":0.00055647275,"about_ca_topic_score_gemma":0.0008513287,"teacher_disagreement_score":0.002651725,"about_ca_system_score_codex":0.00075545313,"about_ca_system_score_gemma":0.00042435597,"threshold_uncertainty_score":0.0088709},"labels":[],"label_agreement":null},{"id":"W2627008401","doi":"10.1038/s41598-017-04194-7","title":"Basic surface features of nuclear FKBPs facilitate chromatin binding","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Florida International University","keywords":"Chromatin; Computational biology; Computer science; Data science; Bioinformatics; Chemistry; Biology; DNA; Biochemistry","score_opus":0.02174198004399765,"score_gpt":0.2626758629727342,"score_spread":0.24093388292873655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2627008401","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939779,0.0008381822,0.0026940254,0.00007991002,0.000020697049,0.0000059674103,0.00013931957,0.000079406585,0.0021644335],"genre_scores_gemma":[0.99721485,0.00011499476,0.00087975437,0.000029906654,0.0000056906642,0.0000030782323,0.0002614952,0.000007522595,0.0014827433],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999286,0.000008351363,0.0000033349863,0.000016492157,0.000020019137,0.000023141512],"domain_scores_gemma":[0.9999304,0.000011162853,0.000015385007,0.000008917475,0.000008729164,0.00002539572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000058245314,0.00018785633,0.00014883677,0.00009736001,0.00016023291,0.00019239492,0.00010869223,0.00019028118,0.003283456],"category_scores_gemma":[0.00013004559,0.00008276728,0.00022163881,0.000057692625,0.00014365793,0.00016976052,0.00030692705,0.00022921215,0.0012203394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005052431,0.0000041095973,0.0005551476,0.000018801253,0.0000039893357,0.00006229626,0.000008933929,0.000034220222,0.9978642,0.00009868952,0.00005209368,0.0012468989],"study_design_scores_gemma":[0.00001999964,0.00015416316,0.05075026,0.000011156706,0.00002396512,0.0010234538,0.00007017879,0.0010998842,0.93659997,0.00022710126,0.010009247,0.000010550291],"about_ca_topic_score_codex":0.00053835363,"about_ca_topic_score_gemma":0.0007633523,"teacher_disagreement_score":0.003283456,"about_ca_system_score_codex":0.00020086297,"about_ca_system_score_gemma":0.0000779263,"threshold_uncertainty_score":0.010984302},"labels":[],"label_agreement":null},{"id":"W2630164044","doi":"10.1007/s11010-017-3100-3","title":"Regulation of cardiac myocyte cell death and differentiation by myocardin","year":2017,"lang":"en","type":"review","venue":"Molecular and Cellular Biochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Myocardin; Serum response factor; Biology; Cell biology; Regulator; Myocyte; Transcription factor; Cardiac myocyte; Cellular differentiation; Cancer research; Genetics; Gene","score_opus":0.016279771056020506,"score_gpt":0.2620599254340734,"score_spread":0.2457801543780529,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2630164044","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00028248885,0.99762803,0.00033211568,0.0003446618,0.00028855508,0.0000047098247,0.00002912175,0.000012810485,0.0010774967],"genre_scores_gemma":[0.0014452497,0.9968701,0.00026388705,0.0002083914,0.00017636413,0.000007819952,0.000046646666,0.0000022525626,0.0009792366],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99989784,0.000010500359,0.0000149120415,0.000020725305,0.000039390605,0.000016701728],"domain_scores_gemma":[0.99989974,0.000030516276,0.0000204065,0.0000044112626,0.000027942458,0.00001701653],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00040252303,0.00079208944,0.0010183909,0.00091457274,0.00020022086,0.0008687559,0.00074264867,0.0007333621,0.0018574763],"category_scores_gemma":[0.0003280303,0.00022214655,0.00025430304,0.0009233843,0.00048042677,0.00088044396,0.0007591419,0.0016314664,0.0014266369],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014383844,0.00005894871,0.00021201356,0.009211035,0.000079113976,0.00027552617,0.000052483592,0.00047186203,0.010316636,0.0056605088,0.024421621,0.9490963],"study_design_scores_gemma":[0.00003444212,0.00007562254,0.0011211318,0.0015427822,0.00013389856,0.0008777733,0.000062364714,0.00016315054,0.0038340804,0.0031328313,0.988996,0.000025980999],"about_ca_topic_score_codex":0.00044679342,"about_ca_topic_score_gemma":0.0010133509,"teacher_disagreement_score":0.0018574763,"about_ca_system_score_codex":0.0005030463,"about_ca_system_score_gemma":0.0007612971,"threshold_uncertainty_score":0.0062139034},"labels":[],"label_agreement":null},{"id":"W2692708557","doi":"10.1016/j.cellsig.2017.06.013","title":"Diverse structures, functions and uses of FK506 binding proteins","year":2017,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"FKBP; Calcineurin; Biology; Peptidylprolyl isomerase; Interactome; Computational biology; Function (biology); Cis-trans-Isomerases; Cell biology; Biochemistry; Medicine; Isomerase; Transplantation","score_opus":0.09695904356124202,"score_gpt":0.32357651031367457,"score_spread":0.22661746675243255,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2692708557","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025074303,0.99808455,0.00026898543,0.0002227538,0.00012757746,0.000002743744,0.000028371385,0.000011279676,0.0010030601],"genre_scores_gemma":[0.0013245725,0.99732816,0.00025153006,0.00014258473,0.00012691319,0.0000037288805,0.00005049452,0.0000017994598,0.0007703204],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998584,0.0000138053665,0.000025998374,0.00003080413,0.000048533755,0.000022481012],"domain_scores_gemma":[0.9998363,0.00006313518,0.000034832792,0.000008052284,0.000040827013,0.00001678208],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000432374,0.00077830954,0.001092993,0.0018272123,0.00029479602,0.0012363325,0.0008788539,0.00080105703,0.0020268103],"category_scores_gemma":[0.0004885114,0.00025755615,0.0003263032,0.001955411,0.00073423865,0.0013964821,0.00077196566,0.0013270595,0.0013281096],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012724516,0.000031167663,0.000247318,0.010656181,0.00006991523,0.00031049395,0.00006902593,0.00043369806,0.007132812,0.007393833,0.019141598,0.9543867],"study_design_scores_gemma":[0.000007906167,0.000030490106,0.0006698861,0.0011982658,0.00008763787,0.0014126551,0.000046687983,0.00007338854,0.0018744906,0.0026816968,0.99189746,0.00001941049],"about_ca_topic_score_codex":0.0010038434,"about_ca_topic_score_gemma":0.0014596129,"teacher_disagreement_score":0.0020268103,"about_ca_system_score_codex":0.0006944067,"about_ca_system_score_gemma":0.0008436245,"threshold_uncertainty_score":0.0067803264},"labels":[],"label_agreement":null},{"id":"W2702369505","doi":"10.1038/s41598-017-04762-x","title":"Heart Failure and MEF2 Transcriptome Dynamics in Response to β-Blockers","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; York University; Canadian Diabetes Association; Heart and Stroke Foundation of Canada","keywords":"Transcriptome; Mef2; Heart failure; Downregulation and upregulation; Biology; Gene expression; Enhancer; Cell biology; Apoptosis; Transcription factor; Muscle hypertrophy; Cancer research; Internal medicine; Gene; Medicine; Endocrinology; Genetics","score_opus":0.00947482863569186,"score_gpt":0.2647380779601981,"score_spread":0.2552632493245062,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2702369505","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99620545,0.000997057,0.00066043687,0.000045206438,0.000014824932,0.00000617041,0.0015128729,0.000021171792,0.00053675147],"genre_scores_gemma":[0.9941729,0.0006716841,0.00054901047,0.00010080148,0.000018156516,0.000042595544,0.0027779029,0.000015560288,0.0016514015],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999224,0.000008393616,0.0000033762183,0.000024983492,0.000017196911,0.000023664477],"domain_scores_gemma":[0.9999378,0.000011028045,0.000019320816,0.000004871696,0.0000104303945,0.000016578377],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009538844,0.00013501027,0.00030191228,0.00020047036,0.00012563248,0.00025563934,0.00006157428,0.00017957453,0.00093940395],"category_scores_gemma":[0.00013234527,0.00009497601,0.00021244187,0.00020783475,0.00009448577,0.00013251814,0.00015800609,0.00024589009,0.00023093194],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052335893,0.00002036687,0.0073657315,0.00005239185,0.000027928329,0.000043539123,0.000048021644,0.00014496263,0.9892347,0.000036612884,0.000109294204,0.0023931146],"study_design_scores_gemma":[0.000025512867,0.00038273845,0.8854515,0.000025228068,0.00008442141,0.00030224843,0.00027706753,0.002122998,0.108822756,0.00016629879,0.0023206205,0.000018624785],"about_ca_topic_score_codex":0.00038571874,"about_ca_topic_score_gemma":0.0005393881,"teacher_disagreement_score":0.00093940395,"about_ca_system_score_codex":0.00009323684,"about_ca_system_score_gemma":0.0000832387,"threshold_uncertainty_score":0.0031425953},"labels":[],"label_agreement":null},{"id":"W2725350803","doi":"","title":"Intracellular Calcium Signalling and the Modulation of Myometrial Genes Associated with Human Labour.","year":2010,"lang":"en","type":"article","venue":"Research Portal (King's College London)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"Signalling; Gene; Calcium; Calcium signaling; Calcium in biology; Intracellular; Cell biology; Reproductive medicine; Reproductive biology; Biology; Endocrinology; Medicine; Andrology; Gynecology; Internal medicine; Chemistry; Genetics; Pregnancy","score_opus":0.03257621611701824,"score_gpt":0.31666776653400497,"score_spread":0.28409155041698675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2725350803","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9106361,0.07366897,0.0011011106,0.003121663,0.00018548366,0.000041972326,0.0018950009,0.000049098333,0.009300408],"genre_scores_gemma":[0.9822735,0.011120185,0.0004925194,0.0003605377,0.000110819456,0.000052438892,0.00082257483,0.000012843217,0.004754627],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987125,0.00003616975,0.00000996645,0.000021239528,0.000031151205,0.000030179168],"domain_scores_gemma":[0.99975735,0.000092798546,0.00008047069,0.000018219365,0.000018844847,0.00003235272],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014072291,0.00013322779,0.000247161,0.00043099298,0.00016620161,0.00032770145,0.00015162694,0.00041854006,0.002582815],"category_scores_gemma":[0.0006663313,0.00011393928,0.0001421388,0.00047401988,0.00044479402,0.00013081408,0.00027010214,0.0005031197,0.00043168213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.009907005,0.00012529558,0.046797775,0.0007617859,0.00006811228,0.004796928,0.0008589724,0.00028782184,0.86994416,0.002386707,0.003393879,0.060671505],"study_design_scores_gemma":[0.00023647533,0.0012380675,0.86625856,0.0002526013,0.00010265052,0.009643479,0.000954186,0.00043157497,0.09202129,0.0032412203,0.025582558,0.000037300502],"about_ca_topic_score_codex":0.000734019,"about_ca_topic_score_gemma":0.000845237,"teacher_disagreement_score":0.002582815,"about_ca_system_score_codex":0.00024432852,"about_ca_system_score_gemma":0.00016684056,"threshold_uncertainty_score":0.0086404085},"labels":[],"label_agreement":null},{"id":"W2726448331","doi":"10.1161/res.109.suppl_1.ap183","title":"Abstract P183: Cardiac Deletion of CaMKII Delta and Gamma Protects Against Heart Failure Despite Activation of Calcineurin Signaling","year":2011,"lang":"en","type":"article","venue":"Circulation Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stuart Olson (Canada)","funders":"","keywords":"Knockout mouse; Calcineurin; Phospholamban; Phosphorylation; Pressure overload; Heart failure; Cardiac function curve; Conditional gene knockout; Chemistry; Muscle hypertrophy; Endocrinology; Internal medicine; Biology; Cell biology; Cardiac hypertrophy; Medicine; Transplantation; Receptor; Phenotype; Gene; Biochemistry","score_opus":0.07427526512412798,"score_gpt":0.32227936130701484,"score_spread":0.24800409618288688,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2726448331","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9793635,0.0032702424,0.0047906316,0.0007937804,0.00040477468,0.00017384074,0.0052255304,0.00041791407,0.0055598803],"genre_scores_gemma":[0.95720154,0.0026437913,0.0047251377,0.0005024199,0.0001643642,0.0003766071,0.00469194,0.00033928777,0.029355051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997693,0.00001686766,0.0000333682,0.00006113926,0.0000614646,0.000057891728],"domain_scores_gemma":[0.9997346,0.000024138146,0.0000901217,0.000021657093,0.000020312074,0.00010928244],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015965657,0.0009099455,0.0006543046,0.0004919671,0.000280301,0.00039045085,0.00053171004,0.0007004414,0.007316819],"category_scores_gemma":[0.00011090215,0.00031604856,0.00045060393,0.0002317894,0.000502346,0.00033608128,0.0003194243,0.0017082861,0.0021947452],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009488025,0.00009732086,0.00015778757,0.00007139151,0.000010420736,0.00019032124,0.000015732965,0.00003408889,0.996494,0.00014810704,0.00020142343,0.0016306074],"study_design_scores_gemma":[0.00038609677,0.0012430594,0.0068161446,0.000043810887,0.00007038033,0.0011552703,0.00006962209,0.000525942,0.98243046,0.00015754729,0.007088932,0.000012743678],"about_ca_topic_score_codex":0.00047308367,"about_ca_topic_score_gemma":0.00044723612,"teacher_disagreement_score":0.007316819,"about_ca_system_score_codex":0.00030620335,"about_ca_system_score_gemma":0.00037148566,"threshold_uncertainty_score":0.024477243},"labels":[],"label_agreement":null},{"id":"W2741512077","doi":"10.1080/15384101.2017.1355180","title":"eEF2K protects <i>MYCN</i>-amplified cells from starvation","year":2017,"lang":"en","type":"letter","venue":"Cell Cycle","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Biology; Starvation; Cell biology; Genetics; Cancer research","score_opus":0.014213281908596035,"score_gpt":0.22774282011878363,"score_spread":0.2135295382101876,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2741512077","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.041456155,0.008750506,0.0017724509,0.8780049,0.043555386,0.00009837201,0.00061373046,0.0005559389,0.02519252],"genre_scores_gemma":[0.3397633,0.015828012,0.0031296536,0.5042061,0.04371807,0.0004917472,0.0006781356,0.00023913223,0.091945834],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996941,0.000052062154,0.00003310061,0.000033047083,0.0001130877,0.00007462611],"domain_scores_gemma":[0.99936813,0.0003252808,0.00005747174,0.000062752726,0.000092550705,0.00009388685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006060234,0.0005691881,0.0006668135,0.00024066376,0.0010431738,0.0011797441,0.0004921828,0.00737661,0.0038464866],"category_scores_gemma":[0.0020689494,0.00025327902,0.0005194655,0.00022116888,0.0009538625,0.00053298596,0.00045105556,0.0063631516,0.0024602646],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002734336,0.00039820114,0.0034889826,0.00020801931,0.000078485114,0.020680312,0.00018197937,0.0007320541,0.055798203,0.019724384,0.81827265,0.07770229],"study_design_scores_gemma":[0.0009790991,0.00067554455,0.0037371013,0.00012637062,0.000084616346,0.011660982,0.00022966588,0.0026670217,0.061242975,0.016541166,0.90196234,0.000093002214],"about_ca_topic_score_codex":0.00078432355,"about_ca_topic_score_gemma":0.0012297261,"teacher_disagreement_score":0.00737661,"about_ca_system_score_codex":0.001250438,"about_ca_system_score_gemma":0.0006522733,"threshold_uncertainty_score":0.012867808},"labels":[],"label_agreement":null},{"id":"W2743668402","doi":"10.1161/hyp.64.suppl_1.071","title":"Abstract 071: Cytokine-angiotensin II Interplay in Cyclophilin D-mediated Vascular Oxidative Stress and Hypertension","year":2014,"lang":"en","type":"article","venue":"Hypertension","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Angiotensin II; Oxidative stress; Mitochondrial ROS; Reactive oxygen species; Mitochondrion; Proinflammatory cytokine; Endothelial dysfunction; Pharmacology; Chemistry; Endothelium; Inflammation; Cytokine; Cell biology; Endocrinology; Internal medicine; Biology; Medicine; Receptor","score_opus":0.010683937092769026,"score_gpt":0.22573176926816405,"score_spread":0.21504783217539503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2743668402","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888071,0.0042898394,0.002007933,0.0006683759,0.00014482233,0.00003977873,0.00061765284,0.000050055845,0.003374503],"genre_scores_gemma":[0.99287343,0.0017693323,0.0010168845,0.00021846805,0.000050886763,0.000023399818,0.0005179028,0.0000068138283,0.003522874],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995196,0.000012768268,0.0000041576263,0.000008793505,0.000010062544,0.000012264552],"domain_scores_gemma":[0.99995446,0.000008038028,0.0000102404965,0.000003468744,0.000005205314,0.000018562572],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008780483,0.00015262784,0.00014278703,0.000086196305,0.00013317025,0.00020368413,0.00009262326,0.00024339338,0.0023855201],"category_scores_gemma":[0.00006447688,0.00007336446,0.00018021332,0.00007955033,0.00017579469,0.00010641335,0.00013220512,0.0003499717,0.00033752492],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050297164,0.000038220478,0.00063042325,0.00008802484,0.000007942494,0.0002093793,0.000012986524,0.000040739727,0.9964302,0.000115458235,0.00020869254,0.0017149604],"study_design_scores_gemma":[0.0001012228,0.0009126762,0.043866966,0.000022989369,0.00004587741,0.00091378536,0.000078236226,0.0011648334,0.9452729,0.00018491187,0.0074282186,0.0000074011523],"about_ca_topic_score_codex":0.000301019,"about_ca_topic_score_gemma":0.0004885312,"teacher_disagreement_score":0.0023855201,"about_ca_system_score_codex":0.0001908705,"about_ca_system_score_gemma":0.00012354033,"threshold_uncertainty_score":0.007980406},"labels":[],"label_agreement":null},{"id":"W2744283080","doi":"10.1139/cjpp-2016-0718","title":"Mechanisms of TFAM-mediated cardiomyocyte protection","year":2017,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health","keywords":"TFAM; Gene knockdown; Cell biology; Biology; Molecular biology; Chemistry; Mitochondrion; Apoptosis; Biochemistry; Mitochondrial biogenesis","score_opus":0.016662054350929274,"score_gpt":0.2641868217898842,"score_spread":0.2475247674389549,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2744283080","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.82962453,0.11578213,0.03734765,0.0026150965,0.0008210118,0.00027382709,0.0010173891,0.0006334686,0.011884891],"genre_scores_gemma":[0.9799897,0.0119634885,0.002778568,0.00037037325,0.0001489055,0.00014471293,0.00030889115,0.000018237783,0.004277125],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997925,0.00003467208,0.0000147740775,0.000040731422,0.00003778122,0.00007959257],"domain_scores_gemma":[0.99982625,0.00002041306,0.000046551955,0.000016625609,0.000038263828,0.000051838444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033222907,0.00042432928,0.0003852557,0.00032152055,0.0002733052,0.00044086154,0.0003486149,0.00058518286,0.001670096],"category_scores_gemma":[0.00025859993,0.00011684745,0.00044963465,0.00011186335,0.00027609023,0.00047826057,0.00041987217,0.00067244994,0.00039172405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00040901694,0.0000610613,0.00075625576,0.00054833764,0.000049844242,0.00049323787,0.00009458071,0.00011676965,0.98144054,0.0020953394,0.00047147923,0.013463518],"study_design_scores_gemma":[0.0001612945,0.0016704142,0.020578027,0.00015590944,0.00015103351,0.00202674,0.00023859592,0.0016741349,0.94797564,0.001994543,0.023348266,0.000025458656],"about_ca_topic_score_codex":0.00024172942,"about_ca_topic_score_gemma":0.00026391432,"teacher_disagreement_score":0.001670096,"about_ca_system_score_codex":0.00041594397,"about_ca_system_score_gemma":0.00019992901,"threshold_uncertainty_score":0.0055870414},"labels":[],"label_agreement":null},{"id":"W2744900448","doi":"10.1038/s41598-017-08315-0","title":"Ectodomain shedding of Limbic System-Associated Membrane Protein (LSAMP) by ADAM Metallopeptidases promotes neurite outgrowth in DRG neurons","year":2017,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Ectodomain; ADAM10; Neurite; Cell biology; Immunoglobulin superfamily; Biology; Metalloproteinase; Dorsal root ganglion; Cell adhesion; Population; Embryonic stem cell; Cell; Disintegrin; Cell adhesion molecule; Neuroscience; Matrix metalloproteinase; Receptor; In vitro; Genetics; Spinal cord; Gene; Medicine","score_opus":0.011937588858753335,"score_gpt":0.24612569211369661,"score_spread":0.23418810325494327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2744900448","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9978452,0.00086340844,0.0006054536,0.00003124904,0.000009480182,0.0000074029635,0.00011951756,0.000017279543,0.0005009433],"genre_scores_gemma":[0.99577624,0.00094784517,0.0012810404,0.000028391929,0.0000054478305,0.000019578283,0.00030891376,0.000007002221,0.0016255288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999033,0.000015809786,0.000012951577,0.000015060042,0.000023771941,0.0000290721],"domain_scores_gemma":[0.9999201,0.000013476473,0.00001833197,0.000009444989,0.000007698857,0.000030828072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012180549,0.000242371,0.0002491465,0.00015627981,0.00009845045,0.00019765826,0.00010695475,0.00015409938,0.0005021821],"category_scores_gemma":[0.00009306204,0.00009456969,0.00027915023,0.000102828184,0.00015141051,0.00016198542,0.00021292552,0.0004913011,0.00024480865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006480711,0.000015260175,0.00014485231,0.000016818094,0.000002391821,0.00005751544,0.000008611414,0.0000222729,0.9992729,0.000013333663,0.000012746766,0.0003685226],"study_design_scores_gemma":[0.000018933984,0.00053377403,0.016322203,0.000009525183,0.000017211598,0.0005222379,0.0000537514,0.00075697055,0.98074406,0.00004465779,0.00097261573,0.0000040814475],"about_ca_topic_score_codex":0.00057880493,"about_ca_topic_score_gemma":0.0011504825,"teacher_disagreement_score":0.00057880493,"about_ca_system_score_codex":0.00031207743,"about_ca_system_score_gemma":0.00020727864,"threshold_uncertainty_score":0.0022642612},"labels":[],"label_agreement":null},{"id":"W2747266872","doi":"10.1136/heartjnl-2016-310696.9","title":"P5 Pharmacological inhibition of plasma membrane calcium ATPASE 4 improves VEGF-induced angiogenesis","year":2016,"lang":"en","type":"article","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"NFAT; Angiogenesis; Calcineurin; Vascular endothelial growth factor; Medicine; Endothelial stem cell; Cell biology; Vascular endothelial growth factor A; Pharmacology; Cancer research; Biology; Biochemistry; Transplantation; In vitro; Internal medicine; VEGF receptors","score_opus":0.026887936215702016,"score_gpt":0.2790733567983089,"score_spread":0.2521854205826069,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2747266872","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9855904,0.0055357353,0.0024878923,0.00064877653,0.000323305,0.00010557617,0.0006528496,0.00041649755,0.0042389384],"genre_scores_gemma":[0.99206287,0.0021595447,0.0013270867,0.00017983577,0.000053895397,0.00008894455,0.0007437544,0.000024364368,0.003359722],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998467,0.000024376432,0.000017842889,0.00002173086,0.00003637069,0.00005297494],"domain_scores_gemma":[0.9999101,0.000017013932,0.000021825745,0.0000073663755,0.000009881224,0.000033801025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014493118,0.0004000579,0.000530937,0.00032387773,0.00018539873,0.00033662276,0.0003839067,0.00049963646,0.0024613112],"category_scores_gemma":[0.00018440824,0.00013880769,0.00037282018,0.00017216231,0.0002619015,0.00029302316,0.00018444729,0.0013732892,0.0004338113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018065231,0.000791181,0.00015570097,0.00026526276,0.000045965862,0.00011746786,0.000033800236,0.00024387374,0.98859406,0.00026150513,0.0007561669,0.0069285887],"study_design_scores_gemma":[0.00040444377,0.006480599,0.003616701,0.000026668427,0.0000956196,0.0003083567,0.000057528097,0.0017057852,0.9797721,0.00015335428,0.007363811,0.000014976077],"about_ca_topic_score_codex":0.00082632963,"about_ca_topic_score_gemma":0.0009146637,"teacher_disagreement_score":0.0024613112,"about_ca_system_score_codex":0.00029838088,"about_ca_system_score_gemma":0.00042977592,"threshold_uncertainty_score":0.008233905},"labels":[],"label_agreement":null},{"id":"W2755237646","doi":"10.1016/j.clim.2017.09.005","title":"Two novel mutations in ZAP70 gene that result in human immunodeficiency","year":2017,"lang":"en","type":"article","venue":"Clinical Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Clinical Research Institute","funders":"Consejo Nacional de Ciencia y Tecnología; McGill University Health Centre","keywords":"Immunodeficiency; T-cell receptor; Mutation; ZAP70; Gene; Primary immunodeficiency; Immunodeficiency Syndrome; Human immunodeficiency virus (HIV); Biology; Genetics; Immunology; T cell; Immune system","score_opus":0.09703584118004423,"score_gpt":0.41675916656317885,"score_spread":0.31972332538313464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2755237646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900276,0.00092185923,0.0024443697,0.00069214887,0.00039404558,0.00008449623,0.00044991268,0.00016388381,0.0048216134],"genre_scores_gemma":[0.9962096,0.00022217767,0.0015356349,0.00026482387,0.0001431812,0.00002835419,0.00022603765,0.000037035614,0.0013332072],"study_design_codex":"case_report","study_design_gemma":"observational","domain_scores_codex":[0.9996654,0.00002833368,0.000040149866,0.000060599574,0.00007459912,0.0001308942],"domain_scores_gemma":[0.9989378,0.00035303473,0.00026436252,0.000049644164,0.000055651184,0.000339601],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001973686,0.0015574677,0.00054576097,0.0011989686,0.00057004887,0.00074756297,0.0010836853,0.0028207358,0.0023875318],"category_scores_gemma":[0.0018422095,0.00036177124,0.00067579193,0.0005888781,0.0011640032,0.0005007278,0.0009547239,0.0012821576,0.0004110568],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009843024,0.00039279927,0.015848588,0.00019318673,0.00008776639,0.7790437,0.0005905806,0.0004705796,0.1863014,0.0037785282,0.0009916705,0.011316924],"study_design_scores_gemma":[0.0004960668,0.0007766528,0.065351166,0.0000553406,0.00019270137,0.8494551,0.0003841428,0.0018163922,0.07144912,0.0017406753,0.008177368,0.000105332954],"about_ca_topic_score_codex":0.0007882918,"about_ca_topic_score_gemma":0.0006189116,"teacher_disagreement_score":0.0028207358,"about_ca_system_score_codex":0.0006701199,"about_ca_system_score_gemma":0.00039110312,"threshold_uncertainty_score":0.007987082},"labels":[],"label_agreement":null},{"id":"W2758671498","doi":"10.1093/nar/gkx852","title":"The basic tilted helix bundle domain of the prolyl isomerase FKBP25 is a novel double-stranded RNA binding module","year":2017,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Biology; Prolyl isomerase; FKBP; Isomerase; Ribosome; RNA; Riboswitch; Ribosome biogenesis; Cell biology; Translation (biology); Oligonucleotide; Biochemistry; DNA; Enzyme; Non-coding RNA; Messenger RNA; Gene; PIN1","score_opus":0.06378863686090934,"score_gpt":0.35098467284343604,"score_spread":0.2871960359825267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2758671498","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98180056,0.0034287504,0.011126906,0.00014605407,0.000050437444,0.00003780419,0.00079321733,0.00025146434,0.002364739],"genre_scores_gemma":[0.9911617,0.0004995057,0.0045023267,0.000058014703,0.000014533528,0.000008755328,0.0009343279,0.000012591365,0.0028082333],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999317,0.0000074987997,0.000004192124,0.000019509183,0.00002112776,0.000015993699],"domain_scores_gemma":[0.9999366,0.0000050713975,0.000022997636,0.0000048948496,0.000004920259,0.000025566105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006869307,0.00033921318,0.0002198739,0.00022076102,0.00026976783,0.0002914637,0.00016366168,0.00022240682,0.0012684992],"category_scores_gemma":[0.00009580723,0.000100340716,0.00023659714,0.00015324733,0.00018706096,0.00019944216,0.00020382012,0.00027122468,0.00073000643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011833654,0.000011190611,0.00088532025,0.000035779572,0.000009400864,0.00026104163,0.000014023004,0.00012728013,0.992819,0.0002711945,0.0001221894,0.0053252666],"study_design_scores_gemma":[0.000025133388,0.00032401757,0.04301869,0.000017868293,0.000038338574,0.0036832138,0.000071074996,0.0014809663,0.9315436,0.00032176045,0.01945025,0.000025101697],"about_ca_topic_score_codex":0.0009250385,"about_ca_topic_score_gemma":0.0009368169,"teacher_disagreement_score":0.0012684992,"about_ca_system_score_codex":0.00033248824,"about_ca_system_score_gemma":0.00018412802,"threshold_uncertainty_score":0.0042435527},"labels":[],"label_agreement":null},{"id":"W2759618212","doi":"10.1016/j.ajhg.2017.08.013","title":"De Novo Mutations in PPP3CA Cause Severe Neurodevelopmental Disease with Seizures","year":2017,"lang":"en","type":"article","venue":"The American Journal of Human Genetics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"Janssen Biotech; National Institute of Neurological Disorders and Stroke; Health Research Council of New Zealand; Eunice Kennedy Shriver National Institute of Child Health and Human Development; AstraZeneca; UCB; Biogen; Gilead Sciences; American Epilepsy Society","keywords":"Proband; Biology; Genetics; Calcineurin; Epilepsy; Exome sequencing; Mutation; Neurodevelopmental disorder; Disease; Gene; Bioinformatics; Medicine; Neuroscience; Internal medicine; Transplantation","score_opus":0.017269065970674347,"score_gpt":0.2906130675289106,"score_spread":0.27334400155823624,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2759618212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98759925,0.001113701,0.0030504658,0.0007364935,0.00024891298,0.00004953983,0.0009562941,0.00015430072,0.0060910196],"genre_scores_gemma":[0.99750644,0.00036077964,0.0006998519,0.00011806015,0.00008250428,0.000010241814,0.0002957896,0.000039757677,0.00088664895],"study_design_codex":"case_report","study_design_gemma":"observational","domain_scores_codex":[0.9996697,0.000046929137,0.00006385035,0.000062158375,0.00010765745,0.000049743732],"domain_scores_gemma":[0.99933976,0.00016223789,0.00022747627,0.000049508842,0.00003512571,0.00018586322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000185617,0.0017598734,0.00056736515,0.0008677428,0.00045207402,0.0005362337,0.00048413765,0.0016133739,0.0018146778],"category_scores_gemma":[0.0008244386,0.00038846972,0.000567525,0.00068535487,0.0011010944,0.00033971932,0.00094852864,0.0010053795,0.0007112063],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007248343,0.00014719149,0.031973306,0.0001351246,0.00025605416,0.6997697,0.0003303845,0.00177084,0.24904417,0.0025576095,0.0024202159,0.01087055],"study_design_scores_gemma":[0.00022765576,0.00042193363,0.14680889,0.000058607122,0.00026060693,0.778865,0.00039518313,0.002599195,0.05617392,0.0046183947,0.0094572,0.00011341487],"about_ca_topic_score_codex":0.0011072366,"about_ca_topic_score_gemma":0.0020719573,"teacher_disagreement_score":0.0018146778,"about_ca_system_score_codex":0.00038599828,"about_ca_system_score_gemma":0.00042528944,"threshold_uncertainty_score":0.0060706735},"labels":[],"label_agreement":null},{"id":"W2763172347","doi":"10.1189/jlb.4a0517-197r","title":"The calcineurin-NFAT axis contributes to host defense during <i>Pseudomonas aeruginosa</i> lung infection","year":2017,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"NFAT; Calcineurin; Biology; Pseudomonas aeruginosa; Transcription factor; Inflammation; Microbiology; Immunology; NFKB1; Cell biology; Cancer research; Transplantation; Medicine; Gene; Biochemistry; Internal medicine; Genetics; Bacteria","score_opus":0.01125739536693364,"score_gpt":0.2895075560949279,"score_spread":0.27825016072799424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2763172347","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9853366,0.008279004,0.0038932126,0.0002283298,0.000051397703,0.00003370345,0.00016721782,0.00017460367,0.0018359758],"genre_scores_gemma":[0.9966838,0.001100402,0.00076113886,0.00003771349,0.00001919463,0.000018613106,0.000112787064,0.000008299263,0.0012581233],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998703,0.000023942752,0.000008318329,0.000021065121,0.00003317977,0.000043162145],"domain_scores_gemma":[0.99992824,0.000008765659,0.000018694684,0.000006182074,0.0000127627545,0.000025350682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016061196,0.00032801685,0.00020926943,0.0002751458,0.0002199278,0.00040152812,0.00013592483,0.00030053698,0.000796325],"category_scores_gemma":[0.000102646256,0.00009481313,0.00019201518,0.00010903677,0.00028097018,0.00023509994,0.00022174491,0.00049810647,0.00015896268],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009899457,0.000013261998,0.00055844424,0.000026598509,0.0000027414442,0.00009290984,0.00001597958,0.00002334587,0.9980052,0.00010536622,0.000031733154,0.0010253744],"study_design_scores_gemma":[0.000027893891,0.00040412828,0.046728197,0.00002263898,0.000036851096,0.0013055028,0.00013565783,0.001488584,0.9439858,0.0004493272,0.005404284,0.000011164971],"about_ca_topic_score_codex":0.0005443207,"about_ca_topic_score_gemma":0.00057811517,"teacher_disagreement_score":0.000796325,"about_ca_system_score_codex":0.00033942296,"about_ca_system_score_gemma":0.00023283642,"threshold_uncertainty_score":0.00266397},"labels":[],"label_agreement":null},{"id":"W2765246760","doi":"10.1039/c7md00267j","title":"Alkyne–azide cycloaddition analogues of dehydrozingerone as potential anti-prostate cancer inhibitors <i>via</i> the PI3K/Akt/NF-kB pathway","year":2017,"lang":"en","type":"article","venue":"MedChemComm","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Plant Biotechnology Institute","funders":"Ministry of Ayurveda, Yoga and Naturopathy, Unani, Siddha and Homoeopathy; Ministry of AYUSH, Government of India","keywords":"PI3K/AKT/mTOR pathway; Prostate cancer; Cycloaddition; Protein kinase B; Chemistry; Cancer research; Alkyne; Azide; Combinatorial chemistry; Pharmacology; Stereochemistry; Biochemistry; Medicine; Cancer; Signal transduction; Internal medicine; Organic chemistry","score_opus":0.009331626449674852,"score_gpt":0.25840842500996697,"score_spread":0.2490767985602921,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2765246760","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9577183,0.008550923,0.008322196,0.00035753098,0.00019614326,0.00025831893,0.0014014225,0.00020682804,0.022988249],"genre_scores_gemma":[0.98931855,0.0037081805,0.0024564872,0.000082567196,0.000015910502,0.000035756322,0.0003729001,0.0000072824205,0.00400239],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999627,0.0000046033197,0.0000031311936,0.000006200195,0.000008268027,0.000015233065],"domain_scores_gemma":[0.99997604,0.0000030037188,0.000007955318,0.000002824549,0.0000043198065,0.000005816185],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000065694214,0.00027075293,0.00014227115,0.0001254864,0.00011189194,0.00011116768,0.00021182376,0.0001236187,0.0022465857],"category_scores_gemma":[0.000056273013,0.00008268208,0.00015664771,0.00015231772,0.00015202824,0.00013151322,0.00013986487,0.00032932218,0.0003331282],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034041796,0.00008288099,0.0003133817,0.0003202005,0.000018186183,0.00042680348,0.000054210817,0.0010839833,0.9841754,0.001299053,0.0005808204,0.011304573],"study_design_scores_gemma":[0.000057497004,0.0011849828,0.0018729474,0.000012599233,0.000027461918,0.0003855165,0.00003629785,0.00050264725,0.98399067,0.00015785199,0.011757421,0.000014038688],"about_ca_topic_score_codex":0.0008782759,"about_ca_topic_score_gemma":0.0029829466,"teacher_disagreement_score":0.0022465857,"about_ca_system_score_codex":0.00026096456,"about_ca_system_score_gemma":0.00025065712,"threshold_uncertainty_score":0.0075156093},"labels":[],"label_agreement":null},{"id":"W2766830503","doi":"10.1111/cid.12549","title":"CyPA and Emmprin play a role in peri‐implantitis","year":2017,"lang":"en","type":"article","venue":"Clinical Implant Dentistry and Related Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Science and Technology Commission of Shanghai Municipality","keywords":"Cypa; Peri-implantitis; Medicine; Bleeding on probing; Dentistry; Metalloproteinase; Matrix metalloproteinase; Periodontitis; Inflammation; Molar; Peri; Internal medicine; Implant; Gastroenterology; Surgery; Immunology","score_opus":0.09059725943475207,"score_gpt":0.4564847512853769,"score_spread":0.36588749185062486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766830503","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99587566,0.0030099892,0.00044757655,0.00007013825,0.000011002598,0.000023995563,0.00008696532,0.000019301764,0.00045533862],"genre_scores_gemma":[0.9968532,0.0013048529,0.00062399346,0.0000430436,0.000019317433,0.0000527978,0.00009675652,0.0000032548214,0.0010027996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978966,0.00004213779,0.000017598659,0.000041362237,0.000052238374,0.000056977424],"domain_scores_gemma":[0.99957377,0.00004302496,0.0002134906,0.000031795524,0.00004770252,0.00009017399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003228533,0.000488663,0.00028752655,0.0005329882,0.00024605705,0.000401508,0.00017177845,0.00050179736,0.0015719037],"category_scores_gemma":[0.00027357767,0.00023657366,0.00038622614,0.00015084619,0.00043516798,0.0003330285,0.0002504825,0.0004813445,0.00023299387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0047661774,0.00051888486,0.029093392,0.00022168791,0.00006325508,0.00054492825,0.000087844346,0.00008866243,0.95472914,0.00012292538,0.00013587641,0.009627311],"study_design_scores_gemma":[0.0001470546,0.011920323,0.58021927,0.000065816326,0.00037197702,0.0036257266,0.00040359626,0.0013661301,0.39800245,0.0002918129,0.003556357,0.000029478566],"about_ca_topic_score_codex":0.00024449048,"about_ca_topic_score_gemma":0.000249718,"teacher_disagreement_score":0.0015719037,"about_ca_system_score_codex":0.00022884508,"about_ca_system_score_gemma":0.00022555845,"threshold_uncertainty_score":0.0052585006},"labels":[],"label_agreement":null},{"id":"W2766939625","doi":"10.1073/pnas.1708852114","title":"Structural insights into binding of STAC proteins to voltage-gated calcium channels","year":2017,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Research Council Canada; Western Economic Diversification Canada; Canadian Institutes of Health Research; Austrian Science Fund; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Canadian Light Source","keywords":"Ryanodine receptor; Membrane protein; Voltage-dependent calcium channel; Depolarization; Endoplasmic reticulum; Cell biology; Signal transducing adaptor protein; Calcium channel; Chemistry; Biology; Biophysics; Calcium; Biochemistry; Membrane; Signal transduction","score_opus":0.05164478880873199,"score_gpt":0.3331418620843193,"score_spread":0.2814970732755873,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2766939625","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9860724,0.0024531425,0.005352717,0.0011711969,0.000066204404,0.00001768986,0.00037180862,0.00021863099,0.0042762295],"genre_scores_gemma":[0.9947595,0.0012608572,0.0025580176,0.00021457396,0.00001491434,0.000008962931,0.00030458655,0.000012424705,0.0008661142],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999291,0.000011149073,0.0000033571625,0.000010191271,0.000027819979,0.000018432145],"domain_scores_gemma":[0.9999112,0.000024623016,0.000015449743,0.0000069136786,0.000013196477,0.000028590177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013796515,0.00043570594,0.00026346883,0.00026267674,0.0004609318,0.00038911094,0.00043110043,0.00050270866,0.0021143106],"category_scores_gemma":[0.00021005406,0.00019357256,0.00022821818,0.0002217834,0.00031603983,0.00035420412,0.00029033353,0.0012425428,0.00043301663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006724994,0.00027384423,0.004317456,0.0003214511,0.00006614157,0.0028437776,0.0003776141,0.016113235,0.94902235,0.012111977,0.0022287075,0.011650929],"study_design_scores_gemma":[0.00027222693,0.00072212657,0.050573412,0.00014358648,0.00019467961,0.00460298,0.0014302159,0.29059473,0.5900528,0.015100877,0.04616427,0.00014812802],"about_ca_topic_score_codex":0.0032236117,"about_ca_topic_score_gemma":0.0032160592,"teacher_disagreement_score":0.0032236117,"about_ca_system_score_codex":0.0006969473,"about_ca_system_score_gemma":0.0004466512,"threshold_uncertainty_score":0.007073045},"labels":[],"label_agreement":null},{"id":"W2770065845","doi":"","title":"HAI-1 maintains the integrity of epidermis through regulation of PAR-2","year":2017,"lang":"en","type":"article","venue":"The Japanese Biochemical Society/The Molecular Biology Society of Japan","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Programs for Assessment of Technology in Health Research Institute","funders":"","keywords":"Epidermis (zoology); Computer science; Business; Biology; Anatomy","score_opus":0.02318161072172175,"score_gpt":0.3074375282020857,"score_spread":0.28425591748036394,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2770065845","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97675997,0.004209829,0.010342248,0.0006148517,0.00021161023,0.00003894014,0.0005397934,0.00025974965,0.0070230425],"genre_scores_gemma":[0.9926104,0.0005777927,0.0018080862,0.00011654553,0.00004204443,0.000027766202,0.0004298769,0.00005027527,0.0043372717],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99977714,0.000027819999,0.000010227712,0.000060807593,0.000041074687,0.00008283898],"domain_scores_gemma":[0.9998574,0.000011072715,0.00003309383,0.000021341202,0.000020458128,0.000056542005],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018127321,0.00034644364,0.00024582914,0.00027605417,0.00045694402,0.000698276,0.00052181684,0.00028018295,0.0019846116],"category_scores_gemma":[0.00015303251,0.000242255,0.00025792918,0.00012721687,0.00032260406,0.0006936117,0.00040664035,0.001320935,0.000701669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008732773,0.000020919435,0.00019157259,0.000020508947,0.0000059747886,0.000046884958,0.000013281955,0.00002577452,0.9977975,0.00047473286,0.0001530606,0.0011625733],"study_design_scores_gemma":[0.00003818175,0.000104138846,0.026141379,0.0000065144595,0.000028560835,0.00039779698,0.00013675928,0.002862048,0.96308213,0.00035362865,0.006836908,0.00001187796],"about_ca_topic_score_codex":0.00043144188,"about_ca_topic_score_gemma":0.0006245533,"teacher_disagreement_score":0.0019846116,"about_ca_system_score_codex":0.00044018583,"about_ca_system_score_gemma":0.00025614095,"threshold_uncertainty_score":0.006639242},"labels":[],"label_agreement":null},{"id":"W2774685356","doi":"10.1016/j.str.2017.11.003","title":"Multivalent Interactions with Fbw7 and Pin1 Facilitate Recognition of c-Jun by the SCFFbw7 Ubiquitin Ligase","year":2017,"lang":"en","type":"article","venue":"Structure","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; University of Toronto; Université de Montréal; Institute for Research in Immunology and Cancer; Hospital for Sick Children","funders":"Vetenskapsrådet; Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Carl Tryggers Stiftelse för Vetenskaplig Forskning","keywords":"PIN1; Ubiquitin ligase; Ubiquitin; Transcription factor; WW domain; c-jun; Phosphorylation; Peptidylprolyl isomerase; NLS; Cell biology; Biology; Isomerase; Chemistry; Biochemistry; Nuclear localization sequence; Gene; Cytoplasm","score_opus":0.020377311567148892,"score_gpt":0.2647281241069034,"score_spread":0.2443508125397545,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2774685356","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98795533,0.00233642,0.0047788383,0.00023416487,0.000055599776,0.000015411255,0.000075922726,0.000074853146,0.0044735367],"genre_scores_gemma":[0.99469006,0.00043915742,0.0014893515,0.00007574681,0.000011226818,0.000010970588,0.00018955542,0.000023974539,0.0030698972],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980766,0.000019904557,0.0000074413083,0.000038780072,0.000053805587,0.00007249917],"domain_scores_gemma":[0.9998896,0.000015925847,0.000026376043,0.000011606338,0.000011011403,0.000045582063],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002032236,0.00038364125,0.00021122998,0.00022923267,0.00045246055,0.0008309765,0.0006048927,0.00048873405,0.00413724],"category_scores_gemma":[0.00029211995,0.00028242476,0.00027122366,0.00014825024,0.00033696517,0.0008670945,0.0011544462,0.000687435,0.0013207406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030448922,0.000036000692,0.00079972437,0.000069765265,0.000024656347,0.00021356603,0.00003144114,0.00017554952,0.99203,0.002185689,0.00025442822,0.003874701],"study_design_scores_gemma":[0.00002460945,0.00007276035,0.0059184046,0.0000115662815,0.000022133036,0.0005934566,0.000100184116,0.0027593626,0.9844514,0.0005176934,0.005517783,0.000010442421],"about_ca_topic_score_codex":0.00032278715,"about_ca_topic_score_gemma":0.00081332866,"teacher_disagreement_score":0.00413724,"about_ca_system_score_codex":0.0006103168,"about_ca_system_score_gemma":0.00021648605,"threshold_uncertainty_score":0.013840497},"labels":[],"label_agreement":null},{"id":"W2793284226","doi":"10.1139/cjpp-2017-0639","title":"High glucose causes vascular dysfunction through Akt/eNOS pathway: reciprocal modulation by juglone and resveratrol","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Resveratrol; Juglone; Protein kinase B; Enos; Internal medicine; Endocrinology; Fructose; Insulin; Chemistry; Vascular smooth muscle; Oxidative stress; Signal transduction; Pharmacology; Nitric oxide; Biology; Biochemistry; Medicine; Nitric oxide synthase","score_opus":0.01003379525469132,"score_gpt":0.24432413362293093,"score_spread":0.23429033836823962,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2793284226","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99065346,0.0067321486,0.0010474102,0.0002225773,0.00009958479,0.000020987705,0.000138331,0.000048022048,0.0010374351],"genre_scores_gemma":[0.9924446,0.0047108904,0.0008990275,0.0001640151,0.000039131413,0.00003451215,0.00022115672,0.00001042203,0.001476227],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998938,0.000021852631,0.000008601371,0.000022601678,0.000018438985,0.0000347058],"domain_scores_gemma":[0.9999528,0.0000045263137,0.000015622749,0.0000048311927,0.000005980857,0.000016229926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112502734,0.0004079274,0.00040590586,0.00021766975,0.00016993267,0.0002739961,0.00016332681,0.0002877539,0.0009315064],"category_scores_gemma":[0.00007014796,0.00016773668,0.0004741706,0.00020158899,0.000252274,0.00027361783,0.00015200056,0.00067779724,0.00014129558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0019477671,0.0002629206,0.00083311636,0.0001897092,0.00005635666,0.00021611816,0.000037243866,0.000090362846,0.99165666,0.00017826764,0.00012265623,0.004408773],"study_design_scores_gemma":[0.00022146088,0.004445292,0.0453352,0.00003188466,0.00028473072,0.00052048976,0.0001605775,0.00083537906,0.9443702,0.00032398253,0.0034469347,0.000023898781],"about_ca_topic_score_codex":0.00033250026,"about_ca_topic_score_gemma":0.00092829426,"teacher_disagreement_score":0.0009315064,"about_ca_system_score_codex":0.00018733065,"about_ca_system_score_gemma":0.00022929147,"threshold_uncertainty_score":0.0031161904},"labels":[],"label_agreement":null},{"id":"W2794081110","doi":"10.1093/nar/gky008","title":"The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability","year":2018,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia; BC Cancer Agency; University of Victoria","funders":"BC Cancer Agency; Canada's Michael Smith Genome Sciences Centre","keywords":"Biology; Cell biology; Prolyl isomerase; Interactome; Mitosis; Chromatin; FKBP; Microtubule polymerization; Microtubule; PIN1; Biochemistry; DNA; Isomerase; Tubulin; Gene","score_opus":0.023028472337080937,"score_gpt":0.3301560289590636,"score_spread":0.30712755662198266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2794081110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98712814,0.0046833805,0.0028394223,0.00019348918,0.000074806594,0.000021845517,0.00035780724,0.00020483827,0.00449623],"genre_scores_gemma":[0.99599236,0.00073662103,0.00032418175,0.000025638148,0.000004815217,0.000007868385,0.00013211246,0.000011995428,0.0027644797],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999915,0.0000096902995,0.0000053917156,0.000020725207,0.000016402619,0.000032811073],"domain_scores_gemma":[0.99993277,0.0000043385985,0.000023434233,0.000005061975,0.000008199434,0.000026081267],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000072231465,0.00026787404,0.00016634336,0.00025380647,0.00033493256,0.0004761338,0.00019802382,0.00027475,0.0020744996],"category_scores_gemma":[0.000113057766,0.00013074662,0.00018672683,0.00011759457,0.0002630015,0.00019299351,0.00025234403,0.00030372624,0.00060218625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027689614,0.000028161374,0.00050112215,0.000037582588,0.000009166904,0.00013225703,0.000015414422,0.00018070616,0.993933,0.00047397512,0.00029821895,0.004113538],"study_design_scores_gemma":[0.000044482415,0.0001988033,0.025740042,0.000022074302,0.000050509985,0.00028351304,0.000087276334,0.00353613,0.9612667,0.0003767565,0.00837584,0.000017935194],"about_ca_topic_score_codex":0.0022992613,"about_ca_topic_score_gemma":0.0028638109,"teacher_disagreement_score":0.0022992613,"about_ca_system_score_codex":0.0006859857,"about_ca_system_score_gemma":0.00032724312,"threshold_uncertainty_score":0.0069399476},"labels":[],"label_agreement":null},{"id":"W2802487663","doi":"10.1126/sciimmunol.aar4135","title":"Mitochondrial cyclophilin D regulates T cell metabolic responses and disease tolerance to tuberculosis","year":2018,"lang":"en","type":"article","venue":"Science Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval; McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Tuberculosis; Cell biology; Mitochondrion; Cell metabolism; Disease; T cell; Cyclophilin; Immunology; Metabolic pathway; Cell; Medicine; Genetics; Immune system; Gene; Internal medicine; Pathology","score_opus":0.007318012053222488,"score_gpt":0.25634617334361803,"score_spread":0.24902816129039554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802487663","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99535453,0.0012151285,0.00093827763,0.00034442774,0.000027291675,0.0000077791055,0.00013251173,0.000045039,0.0019350427],"genre_scores_gemma":[0.99856746,0.00028590596,0.0001230619,0.00003013815,0.000006409443,0.0000036589138,0.000071243005,0.000004076943,0.000908027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999928,0.00001482848,0.0000036773026,0.000012131507,0.000013181202,0.000028066343],"domain_scores_gemma":[0.99993455,0.0000070997817,0.000019309093,0.0000049403634,0.000007759604,0.000026397915],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006743406,0.00010366365,0.00008109645,0.00016111185,0.00018148072,0.00027515684,0.00010740466,0.00020637762,0.0013668134],"category_scores_gemma":[0.000117935284,0.00008120185,0.00009415873,0.00008311877,0.00019046944,0.00011155645,0.0001920584,0.0002471327,0.00021574898],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00047095362,0.000029263892,0.00195977,0.0000204881,0.0000061350456,0.00009758008,0.000015103693,0.00013386141,0.9935848,0.0003981535,0.00022743769,0.0030564151],"study_design_scores_gemma":[0.00011977905,0.00040918813,0.17302924,0.00002074057,0.000051274885,0.000641228,0.00022780633,0.0058236616,0.811705,0.0009796703,0.0069781737,0.000014283674],"about_ca_topic_score_codex":0.0005408734,"about_ca_topic_score_gemma":0.0012116509,"teacher_disagreement_score":0.0013668134,"about_ca_system_score_codex":0.00035484292,"about_ca_system_score_gemma":0.00016675833,"threshold_uncertainty_score":0.0045725107},"labels":[],"label_agreement":null},{"id":"W2802676543","doi":"10.1097/01.gox.0000533888.36841.96","title":"Abstract 23: FK506 Binding Protein Expression Within the Injured Peripheral Nerve","year":2018,"lang":"en","type":"article","venue":"Plastic & Reconstructive Surgery Global Open","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"FKBP; Sciatic nerve; Medicine; Axon; Neurotrophin; Peripheral nervous system; Immunostaining; Neurotrophic factors; Anatomy; Neuroscience; Cell biology; Pathology; Central nervous system; Receptor; Biology; Internal medicine; Immunohistochemistry","score_opus":0.02163456572792943,"score_gpt":0.2755230160703486,"score_spread":0.2538884503424192,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2802676543","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98920035,0.0049916976,0.003040152,0.000121724304,0.000063426596,0.0000285134,0.00039778178,0.00011593135,0.0020403713],"genre_scores_gemma":[0.98337215,0.002771388,0.001725716,0.00007379459,0.000024296818,0.000041058065,0.00055005884,0.00001955386,0.011422021],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999082,0.000006695172,0.000008689377,0.000024862964,0.000027061327,0.000024411504],"domain_scores_gemma":[0.9999311,0.0000055832916,0.000024172748,0.000004493657,0.000013843974,0.00002076899],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008258193,0.00042136817,0.0003126933,0.00020970288,0.0001995949,0.00031760265,0.00016906929,0.00041745644,0.0035279016],"category_scores_gemma":[0.000069121306,0.000079286474,0.00020434007,0.00015152547,0.00029774348,0.00023014964,0.00018755709,0.0004236951,0.00095510884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013901439,0.000016948894,0.00032343398,0.00011631781,0.000005560703,0.0002607216,0.000012526624,0.000022868626,0.9970202,0.000041678595,0.00006543294,0.0019752427],"study_design_scores_gemma":[0.000017610471,0.0009428724,0.036697812,0.000051823667,0.00007826476,0.0026653449,0.00012208652,0.00037584035,0.9551434,0.00007298905,0.0038230317,0.000008977084],"about_ca_topic_score_codex":0.00096666446,"about_ca_topic_score_gemma":0.0008219896,"teacher_disagreement_score":0.0035279016,"about_ca_system_score_codex":0.00031432015,"about_ca_system_score_gemma":0.00024273476,"threshold_uncertainty_score":0.011802018},"labels":[],"label_agreement":null},{"id":"W2803481071","doi":"10.1371/journal.pone.0197491","title":"Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways","year":2018,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":30,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Beatrice Hunter Cancer Research Institute; Izaak Walton Killam Health Centre; Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"TRIF; Signal transduction; Calcineurin; Cell biology; TLR4; Biology; Phosphorylation; Interferon regulatory factors; IκBα; Toll-like receptor; NF-κB; Immunology; Chemistry; Innate immune system; Immune system; Medicine; Transplantation; Internal medicine","score_opus":0.03412710149091789,"score_gpt":0.22329967928677558,"score_spread":0.1891725777958577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2803481071","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98745096,0.006051968,0.003196454,0.00023906534,0.000063835774,0.000051351435,0.00047449148,0.00017334962,0.0022985952],"genre_scores_gemma":[0.99432474,0.001549801,0.0014520533,0.000072672425,0.00001794201,0.00005884451,0.00045393375,0.00002133045,0.002048747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997367,0.000034119646,0.000018965578,0.00006994611,0.000071977556,0.00006823712],"domain_scores_gemma":[0.99975926,0.000022783312,0.00009476837,0.000019005585,0.000040621027,0.000063571526],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019249877,0.00047561486,0.0002586971,0.00036402012,0.00021830449,0.00041465316,0.0003378889,0.00031323844,0.0010109454],"category_scores_gemma":[0.00018798877,0.00013860877,0.00030167177,0.0001504767,0.00034426077,0.00024444622,0.0003177368,0.0005174453,0.00021850085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011594558,0.000019086128,0.00040609305,0.000041158037,0.0000041267317,0.00007244121,0.00001558445,0.00005034576,0.99823713,0.00013925869,0.00003347459,0.0008653513],"study_design_scores_gemma":[0.000050733663,0.00021264143,0.021354523,0.000017299028,0.00003530503,0.00050166965,0.000059708495,0.0020347377,0.9709919,0.00014989042,0.004578236,0.000013295718],"about_ca_topic_score_codex":0.0005924109,"about_ca_topic_score_gemma":0.00079632696,"teacher_disagreement_score":0.0010109454,"about_ca_system_score_codex":0.0005309565,"about_ca_system_score_gemma":0.00037923484,"threshold_uncertainty_score":0.0038523674},"labels":[],"label_agreement":null},{"id":"W2804470050","doi":"10.1139/bcb-2017-0334","title":"Knockdown of the prolyl isomerase Pin1 inhibits Hep-2 cell growth, migration, and invasion by targeting the β-catenin signaling pathway","year":2018,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"PIN1; Gene knockdown; Gene silencing; Cancer research; Transfection; Peptidylprolyl isomerase; Cell growth; Biology; Cyclin D1; Carcinogenesis; Cell biology; Apoptosis; Chemistry; Cell cycle; Cell culture; Cancer; Isomerase; Biochemistry; Genetics; Gene","score_opus":0.005985143019109421,"score_gpt":0.1983029398939495,"score_spread":0.19231779687484007,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2804470050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99088913,0.0031329454,0.0025312263,0.00018840907,0.00003916559,0.00003477183,0.00049052073,0.00012646968,0.002567304],"genre_scores_gemma":[0.99298793,0.0017853515,0.0015133424,0.000056318073,0.000007853984,0.000044364202,0.0006113068,0.0000132854575,0.0029802392],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999373,0.000008196125,0.0000068571894,0.0000119389015,0.000018881774,0.00001685673],"domain_scores_gemma":[0.9999738,0.0000049377213,0.0000071308473,0.0000029737275,0.0000027301944,0.00000838072],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008219155,0.0003088488,0.00019898001,0.00021230841,0.00013568849,0.00022811421,0.00011666709,0.00014678077,0.0012820043],"category_scores_gemma":[0.00005494966,0.00011217419,0.00018618157,0.00010995853,0.00016150252,0.00019324946,0.00012715066,0.00046594915,0.00025330414],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007868427,0.000029912213,0.00017390189,0.000044147306,0.000004829958,0.00004191031,0.000009983416,0.000049581085,0.9981824,0.00007973213,0.0000693518,0.0012356334],"study_design_scores_gemma":[0.00001537389,0.00021630815,0.0035087583,0.000004945382,0.000018297347,0.000171485,0.00002885085,0.0010747619,0.99223316,0.000030181589,0.0026945053,0.0000033246274],"about_ca_topic_score_codex":0.0006433183,"about_ca_topic_score_gemma":0.0013157711,"teacher_disagreement_score":0.0012820043,"about_ca_system_score_codex":0.00023327749,"about_ca_system_score_gemma":0.00024765683,"threshold_uncertainty_score":0.004288733},"labels":[],"label_agreement":null},{"id":"W2808772489","doi":"10.1007/s11033-018-4214-8","title":"Regulation of nuclear factor of activated T cells (NFAT) and downstream myogenic proteins during dehydration in the African clawed frog","year":2018,"lang":"en","type":"article","venue":"Molecular Biology Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"NFAT; Cell biology; Downstream (manufacturing); Dehydration; Biology; Chemistry; Transcription factor; Gene; Biochemistry","score_opus":0.006035421449241867,"score_gpt":0.23408162516271694,"score_spread":0.22804620371347506,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2808772489","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9987658,0.00035689163,0.00030435008,0.00004321347,0.0000065294175,0.000004050513,0.00011106178,0.0000112942025,0.0003968031],"genre_scores_gemma":[0.99721694,0.00018207375,0.00036237205,0.00006381541,0.0000067841197,0.000019199677,0.00018793278,0.000010720118,0.0019501537],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999293,0.000008856477,0.0000035963012,0.000022383854,0.000008173876,0.000027653736],"domain_scores_gemma":[0.9999058,0.000010150181,0.000030595344,0.00000868446,0.000010968349,0.000033751465],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000088553024,0.00016609184,0.00020522712,0.0002347201,0.00037992583,0.00027246927,0.00019971257,0.00025978909,0.001355514],"category_scores_gemma":[0.00011057848,0.00017743965,0.0002177316,0.00008840984,0.00036681976,0.00034486598,0.0003370068,0.0005752109,0.00016907525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032591997,0.000015588443,0.0015117528,0.00002140592,0.0000051637094,0.00008747406,0.000081568476,0.000030836636,0.9972168,0.00013135659,0.000039887047,0.00053212914],"study_design_scores_gemma":[0.0000906624,0.0005302646,0.5269338,0.000025267873,0.00006292176,0.00090204395,0.0010291821,0.0014351567,0.46519706,0.00050163956,0.003251736,0.000040276456],"about_ca_topic_score_codex":0.0016786364,"about_ca_topic_score_gemma":0.0027901477,"teacher_disagreement_score":0.0016786364,"about_ca_system_score_codex":0.00036603955,"about_ca_system_score_gemma":0.00013475664,"threshold_uncertainty_score":0.0045347214},"labels":[],"label_agreement":null},{"id":"W2883337365","doi":"10.1016/j.yjmcc.2018.07.253","title":"HDAC11 regulates interleukin-13 expression in CD4+ T cells in the heart","year":2018,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Peking Union Medical College; National Natural Science Foundation of China","keywords":"HDAC11; Transcription factor; Biology; Immune system; Molecular biology; Pathogenesis; Interleukin 13; Histone; Cell biology; Histone deacetylase; Cancer research; Immunology; Interleukin 4; Gene; Genetics","score_opus":0.007634497824889036,"score_gpt":0.22901193567211647,"score_spread":0.22137743784722744,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2883337365","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99047613,0.0032458066,0.0015493289,0.00037307088,0.00014228332,0.000016555166,0.0005332257,0.00007088009,0.0035926874],"genre_scores_gemma":[0.99265796,0.00096327555,0.00043707382,0.000095616946,0.00005253511,0.00001877552,0.0004650641,0.000027499049,0.005282177],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997367,0.000040810803,0.000012670285,0.000052172825,0.000037377093,0.00012025108],"domain_scores_gemma":[0.9998652,0.000012080721,0.0000295311,0.000011951687,0.00002308318,0.000058101876],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013186494,0.00024811816,0.00026461124,0.00034263707,0.00034699167,0.0006832956,0.00028749037,0.0003153392,0.003838764],"category_scores_gemma":[0.00014578442,0.00028578102,0.00032468152,0.00018437258,0.00041173134,0.0002543913,0.0003402144,0.0007188842,0.0011140413],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010206817,0.0000540706,0.005124897,0.00007821696,0.000022391121,0.00015689386,0.00005570819,0.00009383797,0.9882933,0.00029723207,0.0004553442,0.0043473784],"study_design_scores_gemma":[0.00027351256,0.00063554465,0.30867547,0.00005909609,0.00020190027,0.0008918016,0.0012622933,0.0025383194,0.67453194,0.0004599142,0.010439685,0.000030535597],"about_ca_topic_score_codex":0.0011672921,"about_ca_topic_score_gemma":0.0025797125,"teacher_disagreement_score":0.003838764,"about_ca_system_score_codex":0.0005533654,"about_ca_system_score_gemma":0.00032541069,"threshold_uncertainty_score":0.0128419995},"labels":[],"label_agreement":null},{"id":"W2884743907","doi":"10.1017/cjn.2018.279","title":"38 Untangling the NFI-Calpain signaling axis in malignant glioma","year":2018,"lang":"en","type":"article","venue":"Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Calpastatin; Calpain; Biology; NFAT; Molecular biology; Promoter; Calcineurin; Transcription factor; Gene; Cell biology; Gene knockdown; Gene expression; Biochemistry; Transplantation","score_opus":0.02833088187729986,"score_gpt":0.2666749228322522,"score_spread":0.23834404095495232,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2884743907","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98024637,0.014599881,0.002168219,0.00038659078,0.00004348796,0.00002437065,0.00025045074,0.00009703554,0.0021836057],"genre_scores_gemma":[0.99294513,0.0034715321,0.0010132815,0.000097710334,0.000017848317,0.00001443756,0.00032833984,0.000006793297,0.0021049622],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999553,0.0000042386714,0.000002973202,0.000008335307,0.00001527077,0.000013838157],"domain_scores_gemma":[0.99996376,0.0000031546538,0.00001251391,0.0000025446643,0.0000045046386,0.000013548802],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007012703,0.00024338016,0.00012573865,0.00021503838,0.00010505253,0.00023538637,0.00014185162,0.00019652957,0.0007257914],"category_scores_gemma":[0.000044227934,0.00008231187,0.00018858066,0.00012253721,0.00019496013,0.00015170069,0.0001424146,0.00040694242,0.000197245],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021144761,0.000033012093,0.001460006,0.00008705096,0.0000096710455,0.00033309121,0.000026026351,0.000063012994,0.99227786,0.0003362054,0.00011906628,0.0050434684],"study_design_scores_gemma":[0.000092999355,0.0009831794,0.112994686,0.000040940817,0.00009349726,0.0045599206,0.00024042321,0.0027105892,0.8542294,0.0014570595,0.022578575,0.000018793991],"about_ca_topic_score_codex":0.000788893,"about_ca_topic_score_gemma":0.0014192653,"teacher_disagreement_score":0.000788893,"about_ca_system_score_codex":0.0003370675,"about_ca_system_score_gemma":0.00021745899,"threshold_uncertainty_score":0.0024455786},"labels":[],"label_agreement":null},{"id":"W2885068254","doi":"10.1158/1538-7445.am2018-1936","title":"Abstract 1936: The central role of NFAT signalling in the mechanism of action of the TRPV6 oncochannel inhibitor and clinical candidate SOR-C13","year":2018,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Allison University","funders":"","keywords":"NFAT; Prostate cancer; Cancer research; Reporter gene; Transfection; Medicine; Biology; Chemistry; Internal medicine; Calcineurin; Cell culture; Gene expression; Cancer; Gene; Biochemistry","score_opus":0.07705651906599703,"score_gpt":0.4153374700789012,"score_spread":0.3382809510129042,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2885068254","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92115533,0.040467568,0.010396207,0.0026604391,0.0007096084,0.0005371785,0.005507839,0.0007098067,0.017856047],"genre_scores_gemma":[0.97546715,0.0071736053,0.0037603138,0.0005034332,0.00012239986,0.00021091154,0.0030274242,0.00005609162,0.009678583],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989593,0.000014879269,0.000008725633,0.000017157272,0.000034817494,0.000028498001],"domain_scores_gemma":[0.99994445,0.00000695062,0.000013498204,0.000003976003,0.0000122894935,0.000018912744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00021026707,0.00036681717,0.00045019132,0.00017900766,0.0001694673,0.00041444527,0.00022128849,0.00031799925,0.0061823223],"category_scores_gemma":[0.00014205615,0.000100697864,0.00033700242,0.00017701498,0.00021662067,0.00020438529,0.00012290911,0.0011202786,0.0011318625],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0043186382,0.0004136548,0.0005853033,0.00048583586,0.000047489095,0.0001583506,0.000028144463,0.00030519205,0.95997804,0.00046399343,0.0016212285,0.031594068],"study_design_scores_gemma":[0.0020405422,0.0093027735,0.01505607,0.000098807,0.0001605349,0.0021638137,0.000112933514,0.0021031245,0.9226354,0.0006999109,0.04559193,0.00003413617],"about_ca_topic_score_codex":0.00028225142,"about_ca_topic_score_gemma":0.00069369667,"teacher_disagreement_score":0.0061823223,"about_ca_system_score_codex":0.00031917132,"about_ca_system_score_gemma":0.00036438942,"threshold_uncertainty_score":0.020681918},"labels":[],"label_agreement":null},{"id":"W2886979595","doi":"10.3390/vetsci5030072","title":"CD147 and Cyclooxygenase Expression in Feline Oral Squamous Cell Carcinoma","year":2018,"lang":"en","type":"article","venue":"Veterinary Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Prince Edward Island","funders":"","keywords":"Stroma; Immunohistochemistry; Epithelium; CATS; Prostaglandin E2; Pathology; Cancer research; Cancer; Cyclooxygenase; Cell; Biology; Cell culture; Medicine; Internal medicine; Enzyme","score_opus":0.031165186256746056,"score_gpt":0.29084857390494734,"score_spread":0.25968338764820126,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2886979595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9979279,0.0011368577,0.00014311977,0.000025992014,0.0000039944066,0.000011250234,0.00009542,0.000004516097,0.00065101084],"genre_scores_gemma":[0.9987704,0.00035191193,0.00022410137,0.00001771276,0.000004184613,0.000011317004,0.00017858368,0.000001237021,0.00044056168],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998914,0.000010888286,0.000010140175,0.000021654356,0.000033833963,0.000032003154],"domain_scores_gemma":[0.9998646,0.000030736064,0.000043227108,0.000009329654,0.000026088617,0.00002600007],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018607295,0.00009420427,0.00019939823,0.00075134146,0.00019320248,0.00028145843,0.00009131437,0.0003750898,0.0012513376],"category_scores_gemma":[0.00031725946,0.000107179665,0.00015968458,0.00031040297,0.00019748945,0.00020184266,0.00015553665,0.00018534482,0.00014350747],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013475164,0.000113331786,0.12354598,0.00022399111,0.000041797055,0.002084522,0.00033887674,0.00015957974,0.85822386,0.00019383171,0.0002029507,0.013523681],"study_design_scores_gemma":[0.000020003317,0.000738516,0.8606206,0.000039589315,0.00006415319,0.0070434953,0.0007110371,0.0013899223,0.12521559,0.00011965066,0.0040213503,0.000015919482],"about_ca_topic_score_codex":0.0018010074,"about_ca_topic_score_gemma":0.0023215716,"teacher_disagreement_score":0.0018010074,"about_ca_system_score_codex":0.00043363872,"about_ca_system_score_gemma":0.00012935375,"threshold_uncertainty_score":0.0041861534},"labels":[],"label_agreement":null},{"id":"W2887056667","doi":"","title":"Mechanical stretch regulates TrpC proteins and calcium entry in human myometrial smooth muscle cells.","year":2004,"lang":"en","type":"article","venue":"Research Portal (King's College London)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Women's Health Research Institute","funders":"","keywords":"TRPC; Smooth muscle; Cell biology; Calcium; Chemistry; Biophysics; Transient receptor potential channel; Endocrinology; Biology; Receptor; Biochemistry","score_opus":0.03485813749852204,"score_gpt":0.3265812685002382,"score_spread":0.2917231310017162,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2887056667","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9886226,0.0073486855,0.00045313506,0.0007289043,0.000060649676,0.000021076667,0.00047019185,0.00003341691,0.002261207],"genre_scores_gemma":[0.9964784,0.0012659307,0.00019860889,0.00010190501,0.000027793334,0.000031188385,0.00034555324,0.000006915702,0.0015436105],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998677,0.000025021085,0.000008796824,0.000021437314,0.00003616138,0.000040892588],"domain_scores_gemma":[0.99989486,0.000036855843,0.000022233182,0.000014156725,0.000011568286,0.000020213736],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009964657,0.00009724347,0.00013990742,0.00016174772,0.0002376822,0.0003400886,0.00012773566,0.00031906334,0.0024631007],"category_scores_gemma":[0.00032729865,0.0001046516,0.00016768808,0.00019297696,0.00019871078,0.00034391452,0.00025125002,0.00038352588,0.00042745823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012050323,0.000052864296,0.0011295632,0.00007689509,0.000008789516,0.0002012398,0.00007534074,0.000048988837,0.9920266,0.00022098159,0.00042030608,0.0045333058],"study_design_scores_gemma":[0.0003350548,0.001861563,0.29650718,0.000037436195,0.00006030943,0.0015482409,0.000647648,0.0018948975,0.6869921,0.00077841006,0.009310154,0.000027060212],"about_ca_topic_score_codex":0.0006795184,"about_ca_topic_score_gemma":0.0012172103,"teacher_disagreement_score":0.0024631007,"about_ca_system_score_codex":0.00029433798,"about_ca_system_score_gemma":0.00014424542,"threshold_uncertainty_score":0.008239925},"labels":[],"label_agreement":null},{"id":"W2888714146","doi":"10.3390/cells7090117","title":"Agonist-Biased Signaling via Matrix Metalloproteinase-9 Promotes Extracellular Matrix Remodeling","year":2018,"lang":"en","type":"review","venue":"Cells","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Extracellular matrix; Matrix metalloproteinase; Cell biology; Agonist; Matrix (chemical analysis); Chemistry; Signal transduction; Matrix Metalloproteinase 3; Biology; Receptor; Biochemistry","score_opus":0.0369708872376108,"score_gpt":0.3195608317163613,"score_spread":0.2825899444787505,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888714146","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00039866476,0.99649197,0.00030094918,0.00037401545,0.000325485,0.000005800001,0.00003178598,0.000014378844,0.002056856],"genre_scores_gemma":[0.0018968065,0.9963601,0.00019322697,0.00015340056,0.00014814618,0.0000057116445,0.000037225713,0.0000019363463,0.0012034607],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998896,0.000015579133,0.000017178381,0.000024314511,0.000039038183,0.000014192636],"domain_scores_gemma":[0.99988306,0.000039581126,0.000018680583,0.000004732551,0.00003876011,0.000015136655],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002727024,0.0005629325,0.00057168334,0.0012597602,0.00019258872,0.0007818465,0.00047737427,0.00066585053,0.0025785116],"category_scores_gemma":[0.0003515698,0.00019907129,0.00027271514,0.0009811106,0.00036890584,0.0008374075,0.0005237118,0.0012733084,0.0018713091],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100728765,0.00007174354,0.00038625288,0.010830246,0.000074151285,0.00037440588,0.000077324425,0.0003778071,0.012208465,0.009287045,0.03124959,0.9349622],"study_design_scores_gemma":[0.000011194753,0.00006775604,0.00089427916,0.0010438854,0.000039536677,0.0013296597,0.00004529679,0.000083678715,0.0029730902,0.0021425602,0.9913545,0.000014599541],"about_ca_topic_score_codex":0.0003644634,"about_ca_topic_score_gemma":0.0007320585,"teacher_disagreement_score":0.0025785116,"about_ca_system_score_codex":0.0004755972,"about_ca_system_score_gemma":0.0005816122,"threshold_uncertainty_score":0.008625925},"labels":[],"label_agreement":null},{"id":"W2888960892","doi":"10.1016/j.jsb.2018.08.017","title":"Structural flexibility in the Helicobacter pylori peptidyl-prolyl cis,trans-isomerase HP0175 is achieved through an extension of the chaperone helices","year":2018,"lang":"en","type":"article","venue":"Journal of Structural Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Chaperone (clinical); Isomerase; Population; Chemistry; Biochemistry; Helicobacter pylori; Stereochemistry; Monomer; Biology; Enzyme; Genetics","score_opus":0.03625327523580384,"score_gpt":0.3199247209852457,"score_spread":0.28367144574944186,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2888960892","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99797446,0.0002397962,0.0011211375,0.00005492406,0.000020194799,0.0000031524553,0.00003988428,0.000031471427,0.00051498506],"genre_scores_gemma":[0.9989654,0.00005762515,0.00041056474,0.000031966745,0.0000038740436,0.0000017152219,0.00007197287,0.000009284604,0.00044757494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993265,0.000011488376,0.0000054244842,0.000012020579,0.000018296847,0.000020122388],"domain_scores_gemma":[0.99990857,0.00001237775,0.000025407304,0.000009324042,0.000011038003,0.00003319535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014470624,0.00021306239,0.00016415493,0.00006591648,0.00027622242,0.00034292988,0.00021405342,0.00029871616,0.0011073452],"category_scores_gemma":[0.00021190132,0.00014727931,0.00025561618,0.00008931867,0.00024315009,0.00023242053,0.00028454454,0.00060954393,0.00041386927],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005349958,0.000052251093,0.0012938734,0.00006637348,0.00002901355,0.0005026688,0.000060434897,0.0010904005,0.99119437,0.00094984914,0.0002334418,0.003992315],"study_design_scores_gemma":[0.00011093381,0.00073355326,0.021226501,0.00005227524,0.00009220597,0.0013428697,0.000345644,0.012790524,0.9535955,0.0007925221,0.008853259,0.00006423675],"about_ca_topic_score_codex":0.00081077317,"about_ca_topic_score_gemma":0.00093847985,"teacher_disagreement_score":0.0011073452,"about_ca_system_score_codex":0.000283318,"about_ca_system_score_gemma":0.0001851267,"threshold_uncertainty_score":0.0037044287},"labels":[],"label_agreement":null},{"id":"W2890277829","doi":"10.1016/j.ceca.2018.09.002","title":"Calmodulin-binding proteins: A journey of 40 years","year":2018,"lang":"en","type":"review","venue":"Cell Calcium","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":61,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"Heart and Stroke Foundation of Canada","keywords":"Calmodulin; Calcineurin; Phosphatase; Calmodulin-binding proteins; Calpain; Biology; Biochemistry; Cell biology; Protein kinase A; Kinase; Phosphorylation; Chemistry; Enzyme; Transplantation; Internal medicine; Medicine","score_opus":0.06653128051543152,"score_gpt":0.3367888221698698,"score_spread":0.27025754165443827,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2890277829","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000052771542,0.9980872,0.00013673284,0.0008963238,0.00043896947,0.0000014762436,0.000009931586,0.000006803075,0.00036979673],"genre_scores_gemma":[0.00073739316,0.9966018,0.00026896494,0.0007521244,0.0008712424,0.000004429642,0.000028024651,0.000002255464,0.0007337506],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99977154,0.000031955526,0.000031593056,0.00004391832,0.00008820175,0.00003280846],"domain_scores_gemma":[0.99948835,0.00022081696,0.000060744478,0.000015009926,0.00013901448,0.000075936536],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008991914,0.0007790227,0.0012917848,0.0012351742,0.00036636213,0.0014657526,0.0009608302,0.00175955,0.0026844302],"category_scores_gemma":[0.0012858687,0.00027482572,0.0002985906,0.0016195932,0.0009416896,0.0019927372,0.001033883,0.0027287796,0.0014438027],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013106164,0.000047864403,0.00024702703,0.009627236,0.0000730749,0.00020526716,0.00012724633,0.0002473092,0.0025936388,0.009115601,0.11581232,0.8617723],"study_design_scores_gemma":[0.000010748589,0.000027470081,0.00030670193,0.001272806,0.00004270023,0.00045053274,0.000054149685,0.0000611519,0.00024382088,0.0025156979,0.9950046,0.0000095231035],"about_ca_topic_score_codex":0.0010014523,"about_ca_topic_score_gemma":0.0022724236,"teacher_disagreement_score":0.0026844302,"about_ca_system_score_codex":0.0008716837,"about_ca_system_score_gemma":0.0017303366,"threshold_uncertainty_score":0.008980334},"labels":[],"label_agreement":null},{"id":"W2891451511","doi":"10.1038/s41598-018-31784-w","title":"ADAP1 limits neonatal cardiomyocyte hypertrophy by reducing integrin cell surface expression","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada; Heart and Stroke Foundation of Canada","keywords":"Muscle hypertrophy; Cell biology; Cell; Integrin; Myocyte; Bioinformatics; Biology; Medicine; Internal medicine; Biochemistry","score_opus":0.009576151281703669,"score_gpt":0.23113611986859406,"score_spread":0.2215599685868904,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2891451511","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9934384,0.002852391,0.0015025532,0.00013056632,0.000036053658,0.000022732687,0.0004344779,0.0000975458,0.0014852632],"genre_scores_gemma":[0.99311453,0.0022447896,0.0014123651,0.00006085649,0.00001970796,0.000049437393,0.00053493987,0.000028389668,0.0025350137],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989283,0.000013634333,0.000011173703,0.000026712376,0.000028774833,0.00002688117],"domain_scores_gemma":[0.99990225,0.00001614117,0.00002808929,0.000009570307,0.000010947096,0.000032927674],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000119436176,0.00033727018,0.00027767758,0.00017135541,0.00010863316,0.00023440408,0.00024441685,0.00025907005,0.0018171085],"category_scores_gemma":[0.000108676584,0.0001117123,0.00017071806,0.00008963257,0.00023787397,0.0001753676,0.0002476391,0.00060388923,0.00034670334],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019224365,0.00004820826,0.00023807774,0.00008773857,0.000005394841,0.000039458344,0.000012397376,0.00006031098,0.9963289,0.000083751314,0.000073373085,0.002830127],"study_design_scores_gemma":[0.00003254344,0.00062416174,0.010430874,0.000011567591,0.00002972695,0.00025946848,0.000047562327,0.0007362429,0.9833224,0.0000614854,0.0044378666,0.0000061272935],"about_ca_topic_score_codex":0.0001660429,"about_ca_topic_score_gemma":0.0003900727,"teacher_disagreement_score":0.0018171085,"about_ca_system_score_codex":0.0001738068,"about_ca_system_score_gemma":0.00019227077,"threshold_uncertainty_score":0.0060788393},"labels":[],"label_agreement":null},{"id":"W2895739306","doi":"10.1016/j.critrevonc.2018.09.017","title":"Crosstalk in cancer resistance and metastasis","year":2018,"lang":"en","type":"review","venue":"Critical Reviews in Oncology/Hematology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":78,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Crosstalk; Metastasis; CD44; Drug resistance; Chemotherapy; Cancer research; Medicine; Cancer; Cancer chemotherapy; Cancer treatment; Cancer cell; Tumor microenvironment; Bioinformatics; Biology; Tumor cells; Internal medicine; Cell; Genetics","score_opus":0.10951879324645543,"score_gpt":0.47477112477453154,"score_spread":0.3652523315280761,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2895739306","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00008439392,0.9973335,0.00022846872,0.00057588576,0.000749297,0.0000040726545,0.000017334443,0.000011996287,0.000995029],"genre_scores_gemma":[0.0010152333,0.99642307,0.0002445203,0.0004912385,0.0007220043,0.0000083699615,0.000033180742,0.0000025044976,0.0010598813],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99978465,0.000039890834,0.000022641234,0.000037348564,0.000082087776,0.000033338496],"domain_scores_gemma":[0.9997428,0.00010150835,0.000033998767,0.000009775111,0.000071862356,0.00004009466],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006745665,0.0010674761,0.0011965677,0.0014887417,0.0003299655,0.0015285173,0.0008968376,0.001280626,0.00438877],"category_scores_gemma":[0.0007340928,0.00029623572,0.0003717572,0.0014370654,0.00081150356,0.0012778534,0.0010139535,0.002814993,0.0020521092],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100812314,0.00006450406,0.00013945148,0.0077002365,0.00006003582,0.00019877274,0.000050688428,0.00040494298,0.0034034187,0.00941954,0.07798621,0.9004714],"study_design_scores_gemma":[0.000020568732,0.000041368894,0.0003258465,0.0015061738,0.0000664096,0.0005202562,0.00004923916,0.00010002173,0.00062765984,0.003948203,0.99278027,0.000014132895],"about_ca_topic_score_codex":0.000518059,"about_ca_topic_score_gemma":0.0012201262,"teacher_disagreement_score":0.00438877,"about_ca_system_score_codex":0.00072207564,"about_ca_system_score_gemma":0.001198855,"threshold_uncertainty_score":0.014681935},"labels":[],"label_agreement":null},{"id":"W2896608282","doi":"10.1158/1078-0432.ccr-18-0704","title":"Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer","year":2018,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Terry Fox Foundation; Camargo Foundation; Agence Nationale de la Recherche","keywords":"Taxane; Translation (biology); Prostate cancer; Prostate; Cancer; Biology; Internal medicine; Cancer research; Medicine; Genetics; Messenger RNA; Breast cancer; Gene","score_opus":0.2187812640927564,"score_gpt":0.4967308246524777,"score_spread":0.2779495605597213,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2896608282","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952683,0.0023739897,0.0012150557,0.000100986006,0.000022920305,0.000017755292,0.00038180663,0.00008369304,0.0005355458],"genre_scores_gemma":[0.99581283,0.00086205266,0.0011975277,0.000040920248,0.000005084908,0.00002797065,0.0007232438,0.000013288192,0.0013170476],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991596,0.000011408919,0.000007176354,0.000016496306,0.000031510226,0.000017511693],"domain_scores_gemma":[0.99995315,0.0000064934743,0.00001415531,0.0000042097704,0.000010307266,0.000011731706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008062693,0.00025089143,0.00026657621,0.0002606644,0.00021538907,0.00024262971,0.00015341237,0.00024806472,0.0008176437],"category_scores_gemma":[0.0000810622,0.00012048592,0.00024767808,0.00016653824,0.00014829336,0.000082232,0.00009665743,0.00035567707,0.00027998185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100479025,0.00001591766,0.00053314184,0.000042313637,0.000009357501,0.00005430982,0.000008019811,0.000089050045,0.99821174,0.000031060114,0.00006380127,0.0008408514],"study_design_scores_gemma":[0.000021514055,0.00021807312,0.016779741,0.0000057364764,0.00003798342,0.0003325497,0.000031583255,0.002459742,0.9777346,0.000029370967,0.0023425,0.0000065641325],"about_ca_topic_score_codex":0.0015658649,"about_ca_topic_score_gemma":0.001844948,"teacher_disagreement_score":0.0015658649,"about_ca_system_score_codex":0.0004888097,"about_ca_system_score_gemma":0.00022201148,"threshold_uncertainty_score":0.003546536},"labels":[],"label_agreement":null},{"id":"W2897135952","doi":"10.3390/biom8040112","title":"The Multiple Roles of Peptidyl Prolyl Isomerases in Brain Cancer","year":2018,"lang":"en","type":"review","venue":"Biomolecules","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Canadian Institutes of Health Research","keywords":"Brain cancer; Isomerase; Prolyl isomerase; PIN1; FKBP; Neuroscience; Biology; Computational biology; Cancer; Genetics; Gene","score_opus":0.03301098272307272,"score_gpt":0.34654291336785886,"score_spread":0.3135319306447861,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897135952","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0001510947,0.99845326,0.000094497205,0.00030477086,0.0001283288,0.0000023966563,0.000014045179,0.0000067355645,0.0008448863],"genre_scores_gemma":[0.0006423014,0.9986368,0.00009863133,0.00010612229,0.000100107754,0.0000026118119,0.00001971786,9.268392e-7,0.0003928143],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998846,0.000016035803,0.000021610369,0.000020459038,0.00004392848,0.000013285199],"domain_scores_gemma":[0.9998393,0.00006051632,0.00002596839,0.0000047357435,0.00004678105,0.000022667014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030297975,0.0005621082,0.0007277514,0.0020108607,0.00030293904,0.0007021045,0.00045754138,0.0006841466,0.002376319],"category_scores_gemma":[0.0003855748,0.0001800086,0.0003637806,0.0017375404,0.00038405784,0.001006354,0.0005844883,0.0013338317,0.0011874569],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006419508,0.000049991748,0.00034988628,0.013427749,0.00008517096,0.00053942786,0.000093875606,0.00030900716,0.0027893516,0.0040627695,0.029285613,0.9489429],"study_design_scores_gemma":[0.000009593137,0.000060889917,0.001118501,0.0021708477,0.000077295444,0.0030967547,0.00006847435,0.00005704928,0.0005971086,0.0019889202,0.9907391,0.000015537971],"about_ca_topic_score_codex":0.0009208131,"about_ca_topic_score_gemma":0.0016891871,"teacher_disagreement_score":0.002376319,"about_ca_system_score_codex":0.0005556115,"about_ca_system_score_gemma":0.0009202738,"threshold_uncertainty_score":0.007949591},"labels":[],"label_agreement":null},{"id":"W2897439491","doi":"10.1111/his.13764","title":"Clinicopathological significance of RCAN2 production in gastric carcinoma","year":2018,"lang":"en","type":"article","venue":"Histopathology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"Japan Society for the Promotion of Science","keywords":"Transfection; Small interfering RNA; Cancer research; Immunohistochemistry; RNA; Cancer; Biology; Cell growth; Cell culture; Protein kinase B; Molecular biology; Medicine; Pathology; Internal medicine; Gene; Phosphorylation; Cell biology","score_opus":0.023798209086551527,"score_gpt":0.27620739000525496,"score_spread":0.25240918091870346,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2897439491","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99795216,0.0010059316,0.00021915103,0.000025097303,0.000004755875,0.000008348525,0.00013170503,0.000012217319,0.0006406447],"genre_scores_gemma":[0.9994204,0.00013370633,0.00014734175,0.000006634905,0.000005730696,0.000007641187,0.0001331932,0.000001936071,0.00014342557],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998447,0.000030009613,0.000017610677,0.000044651802,0.000041001065,0.000021996075],"domain_scores_gemma":[0.9996112,0.00009061289,0.00013221809,0.00004069251,0.000056981815,0.00006834434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034937816,0.00017945233,0.00014559091,0.00075289747,0.00023586242,0.00036918256,0.00015481561,0.0002633194,0.0011568156],"category_scores_gemma":[0.00060154946,0.00011267881,0.00013517671,0.0005330233,0.00032132686,0.00018300676,0.00017739972,0.00015374142,0.00017280143],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011016721,0.000023385237,0.91900975,0.00009575948,0.000059888524,0.0033131393,0.00014369373,0.00018617442,0.07094496,0.000087325134,0.00020446093,0.0048298407],"study_design_scores_gemma":[0.000020524643,0.00013597881,0.9766618,0.000008685534,0.000076184224,0.008860311,0.00021233546,0.0006727612,0.011440202,0.000101207705,0.0018001876,0.000009760931],"about_ca_topic_score_codex":0.00047767512,"about_ca_topic_score_gemma":0.0007134614,"teacher_disagreement_score":0.0011568156,"about_ca_system_score_codex":0.00023080932,"about_ca_system_score_gemma":0.00013890144,"threshold_uncertainty_score":0.0038698912},"labels":[],"label_agreement":null},{"id":"W2898496239","doi":"10.15252/embr.201745536","title":"FMRP recruitment of β‐catenin to the translation pre‐initiation complex represses translation","year":2018,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Canadian Institutes of Health Research; York University; Government of Canada","keywords":"Translation (biology); Biology; Cell biology; Catenin; Genetics; Eukaryotic translation; Computational biology; Signal transduction; Messenger RNA; Gene; Wnt signaling pathway","score_opus":0.11646249390205261,"score_gpt":0.3459438932356195,"score_spread":0.22948139933356693,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2898496239","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98564214,0.0033410157,0.0045759585,0.00048000863,0.0001538222,0.000025348285,0.00035087933,0.00031159885,0.00511922],"genre_scores_gemma":[0.99168867,0.00058021065,0.0014889188,0.00012538795,0.00004382787,0.00002032368,0.00064014026,0.00007006913,0.0053423755],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996191,0.000031686264,0.000028931125,0.00010133698,0.000109836714,0.000109001914],"domain_scores_gemma":[0.99967945,0.00006551875,0.000072270566,0.000053696684,0.00004326042,0.000085867556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000298092,0.00049454713,0.00027979614,0.00031388717,0.0004130528,0.0008789309,0.0002895686,0.00043413258,0.002767775],"category_scores_gemma":[0.00045795194,0.00034796857,0.00038163646,0.00014863709,0.00048529252,0.00041354488,0.0005364157,0.001134417,0.0014448412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013226278,0.00001560122,0.00020775358,0.00003375109,0.0000057843768,0.00010007407,0.000023469212,0.000041535775,0.99738234,0.0003317791,0.00016421343,0.0015614036],"study_design_scores_gemma":[0.000022863134,0.00007047192,0.008089487,0.000008937209,0.0000072464954,0.00023640833,0.000033764332,0.0007221163,0.986565,0.00015783928,0.004078532,0.000007358758],"about_ca_topic_score_codex":0.0009508128,"about_ca_topic_score_gemma":0.0022592184,"teacher_disagreement_score":0.002767775,"about_ca_system_score_codex":0.0008989945,"about_ca_system_score_gemma":0.0004113139,"threshold_uncertainty_score":0.009259105},"labels":[],"label_agreement":null},{"id":"W2899048634","doi":"10.1016/j.bbrep.2018.10.012","title":"The calcium sensitizer drug MCI-154 binds the structural C-terminal domain of cardiac troponin C","year":2018,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; University of Alberta; British Deer Society","keywords":"Terminal (telecommunication); Calcium; Drug; Drug target; Troponin; Chemistry; Drug discovery; Troponin C; C-terminus; Biochemistry; Cardiology; Pharmacology; Internal medicine; Medicine; Computer science; Myocardial infarction","score_opus":0.005933386979033197,"score_gpt":0.24405960624670436,"score_spread":0.23812621926767116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899048634","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9897905,0.0037977258,0.0015037998,0.00025762926,0.000075978925,0.00008386073,0.00023094263,0.000061055674,0.004198509],"genre_scores_gemma":[0.99281865,0.0017446064,0.002357122,0.000121992925,0.000027054872,0.000043327636,0.0004124646,0.000009277798,0.002465445],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998908,0.000018937177,0.000008321364,0.000020318756,0.000033468063,0.000028105958],"domain_scores_gemma":[0.9999337,0.000017830289,0.00001430555,0.0000074036516,0.000008613437,0.000018212486],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012259751,0.00032980792,0.00041025892,0.0001954828,0.00019836266,0.00025051043,0.00035158472,0.00040846536,0.0022716993],"category_scores_gemma":[0.00016346671,0.00012363485,0.0001979217,0.00013464336,0.0002947179,0.00014190181,0.00013062211,0.0007237904,0.00035084257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001018021,0.00004594106,0.00011364971,0.000049372902,0.000008303962,0.000056695455,0.000011256784,0.00005995033,0.99787784,0.00014447127,0.0000755307,0.0014551388],"study_design_scores_gemma":[0.00006385333,0.0013200018,0.0023830968,0.000008223467,0.00002320333,0.00022452613,0.000021546504,0.0003941137,0.99272764,0.00003190008,0.0027942397,0.000007599679],"about_ca_topic_score_codex":0.001675101,"about_ca_topic_score_gemma":0.0021513873,"teacher_disagreement_score":0.0022716993,"about_ca_system_score_codex":0.00046631682,"about_ca_system_score_gemma":0.0003741352,"threshold_uncertainty_score":0.007599652},"labels":[],"label_agreement":null},{"id":"W2899586390","doi":"10.1002/cbf.3362","title":"Effects of anoxic exposure on the nuclear factor of activated T cell (NFAT) transcription factors in the stress‐tolerant wood frog","year":2018,"lang":"en","type":"article","venue":"Cell Biochemistry and Function","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"NFAT; Calcineurin; Transcription factor; Biology; Cell biology; Lithobates; Biochemistry; Internal medicine; Endocrinology; Gene; Transplantation","score_opus":0.007525668742942827,"score_gpt":0.18923768135167449,"score_spread":0.18171201260873165,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2899586390","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99818534,0.0009574384,0.00024986337,0.000053236028,0.00004709619,0.000009605473,0.00011970467,0.000011570711,0.00036600247],"genre_scores_gemma":[0.996675,0.0007798822,0.00025399672,0.00007711929,0.000023955032,0.00004379654,0.00032074194,0.0000045176857,0.0018209573],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999205,0.000010949729,0.0000068751997,0.000022360018,0.000013829786,0.000025482856],"domain_scores_gemma":[0.99993014,0.000008470572,0.000021357842,0.000007425234,0.00000883434,0.000023854293],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008194214,0.00025333624,0.00018275635,0.0001624826,0.00021731452,0.00016878934,0.00011747084,0.00018958721,0.0014469568],"category_scores_gemma":[0.00007515104,0.0001024541,0.0003190095,0.0001194151,0.00024277317,0.00016254891,0.00012704873,0.00042060466,0.00011000163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013586954,0.00017479967,0.0017977565,0.00006290748,0.000027255272,0.00013998491,0.00007417595,0.00005368855,0.9944564,0.000042163258,0.00009377408,0.0017184531],"study_design_scores_gemma":[0.000109466,0.0048354683,0.21087778,0.000027219463,0.00014796645,0.0006516027,0.0006401133,0.0012533999,0.7779051,0.00018020115,0.0033432527,0.000028434844],"about_ca_topic_score_codex":0.001143681,"about_ca_topic_score_gemma":0.0018766748,"teacher_disagreement_score":0.0014469568,"about_ca_system_score_codex":0.00018441406,"about_ca_system_score_gemma":0.000111739144,"threshold_uncertainty_score":0.004840553},"labels":[],"label_agreement":null},{"id":"W2900335512","doi":"10.1038/s41598-018-34906-6","title":"Cytoplasmic Pin1 expression is increased in human cutaneous melanoma and predicts poor prognosis","year":2018,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Vancouver Coastal Health Research Institute; University of British Columbia; Vancouver Coastal Health; Vancouver General Hospital","funders":"National Natural Science Foundation of China","keywords":"Melanoma; PIN1; Expression (computer science); Cytoplasm; Medicine; Cancer research; Computational biology; Bioinformatics; Biology; Computer science; Cell biology; Genetics; Gene","score_opus":0.009992184791316853,"score_gpt":0.24833836267010898,"score_spread":0.23834617787879211,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2900335512","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99872285,0.0005321136,0.00022149898,0.000018002698,0.00000402812,0.0000039827214,0.00018264407,0.000007833021,0.00030687897],"genre_scores_gemma":[0.99951553,0.000097761746,0.00007991648,0.0000038654057,0.000004059883,0.0000031975887,0.0001724973,0.0000011520983,0.00012211308],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9998914,0.00002288694,0.000008547772,0.0000324218,0.000025617883,0.000019018105],"domain_scores_gemma":[0.9996717,0.0000751429,0.00014290602,0.000023281249,0.000040360886,0.00004656305],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023579138,0.00019227003,0.00019995682,0.0005820215,0.00017662974,0.0002908527,0.00011742672,0.00019639039,0.0012901162],"category_scores_gemma":[0.0005894989,0.00014984683,0.00014053987,0.00041614505,0.00017394855,0.00015597076,0.0002091665,0.00020080227,0.00020278346],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071018055,0.000019069977,0.97047555,0.000043459168,0.00006420882,0.00052460626,0.000047633566,0.00014457338,0.023256639,0.000025733583,0.00017021038,0.0045181513],"study_design_scores_gemma":[0.0000055721607,0.000054880675,0.99671835,0.0000044645576,0.000026285668,0.0012234235,0.000058729198,0.00032035846,0.0013459321,0.000035512076,0.0002036604,0.0000028690688],"about_ca_topic_score_codex":0.00037091982,"about_ca_topic_score_gemma":0.00043375386,"teacher_disagreement_score":0.0012901162,"about_ca_system_score_codex":0.000095052754,"about_ca_system_score_gemma":0.000050003237,"threshold_uncertainty_score":0.004315853},"labels":[],"label_agreement":null},{"id":"W2901679055","doi":"10.1096/fasebj.31.1_supplement.771.5","title":"Uncovering Novel Substrates and Functions for the Calcineurin Phosphatase in Human Cells","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"","keywords":"Phosphatase; Proteome; Human proteome project; Calcineurin; Dephosphorylation; Computational biology; Biology; Cell biology; Phosphorylation; Biochemistry; Chemistry; Proteomics; Gene","score_opus":0.028449911486722178,"score_gpt":0.2821006148929326,"score_spread":0.25365070340621043,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2901679055","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9783927,0.004053886,0.015494969,0.00014764849,0.000010825867,0.000021932097,0.0006275549,0.0001365929,0.001113901],"genre_scores_gemma":[0.9844752,0.0017534556,0.012472425,0.00007145949,0.000006440033,0.000010627099,0.000858123,0.000008605447,0.000343609],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991953,0.000010113043,0.0000052621513,0.000030464538,0.000026597072,0.000008008823],"domain_scores_gemma":[0.99995244,0.000015168283,0.000014656093,0.000005364753,0.0000061540172,0.0000061507203],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019030442,0.00028415848,0.00035504426,0.000236259,0.00013496047,0.0004008615,0.00023543104,0.0003152042,0.0004437395],"category_scores_gemma":[0.00021687134,0.00013495261,0.00031463648,0.00040707493,0.00014677153,0.0001707521,0.0001398881,0.00014616581,0.00017113188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003726832,0.000057096924,0.016391674,0.00022677727,0.000058405803,0.00058574683,0.00007390977,0.009062815,0.9528102,0.0015598448,0.00042630875,0.018374577],"study_design_scores_gemma":[0.000042240197,0.000317826,0.046174005,0.00003059276,0.00014262131,0.001972165,0.00019400532,0.13963155,0.80015767,0.0020568313,0.00924407,0.00003646559],"about_ca_topic_score_codex":0.0012799901,"about_ca_topic_score_gemma":0.001434219,"teacher_disagreement_score":0.0012799901,"about_ca_system_score_codex":0.00038926696,"about_ca_system_score_gemma":0.0002900585,"threshold_uncertainty_score":0.0028243065},"labels":[],"label_agreement":null},{"id":"W2902492842","doi":"10.1038/s41557-018-0187-4","title":"Rapamycin-inspired macrocycles with new target specificity","year":2018,"lang":"en","type":"article","venue":"Nature Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":124,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Cancer Institute; National Institutes of Health","keywords":"FKBP; Chemistry; Effector; Calcineurin; Chemical biology; Drug discovery; Phage display; HEK 293 cells; Computational biology; Biochemistry; Cell biology; Receptor; Peptide; Biology","score_opus":0.0054359350667017425,"score_gpt":0.23422348094317189,"score_spread":0.22878754587647016,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2902492842","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.79685736,0.030419292,0.049857255,0.001494215,0.0014478201,0.00049229566,0.0014353583,0.0029443398,0.11505211],"genre_scores_gemma":[0.9647048,0.007970652,0.013772439,0.00084033696,0.00015920996,0.0004218948,0.00037579215,0.00017132126,0.011583711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990714,0.000015460351,0.0000063289363,0.000028148961,0.000015964475,0.000026987744],"domain_scores_gemma":[0.99993145,0.000015835853,0.00001569255,0.000009382334,0.000007850417,0.000019777042],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015728787,0.0005440553,0.0004226118,0.00031005486,0.00027322705,0.00058540603,0.000440385,0.0004337979,0.0035461495],"category_scores_gemma":[0.00021797857,0.00023694387,0.00021892773,0.00022655228,0.00035643487,0.00050152,0.0007310588,0.0007338578,0.0011228566],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007718399,0.00016515829,0.00031741537,0.0008675009,0.000072625066,0.00062141044,0.00024166808,0.0056721373,0.8482217,0.059716396,0.008451766,0.07488048],"study_design_scores_gemma":[0.00020298782,0.002749017,0.0013237277,0.00008350784,0.0000858763,0.0006370375,0.00006193359,0.008703423,0.82525986,0.0070964056,0.15366897,0.00012733898],"about_ca_topic_score_codex":0.00020746232,"about_ca_topic_score_gemma":0.0005423465,"teacher_disagreement_score":0.0035461495,"about_ca_system_score_codex":0.00037821382,"about_ca_system_score_gemma":0.00017162439,"threshold_uncertainty_score":0.011863053},"labels":[],"label_agreement":null},{"id":"W2911884050","doi":"10.1007/s12104-019-09878-x","title":"15N, 13C and 1H resonance assignments of FKBP12 proteins from the pathogenic fungi Mucor circinelloides and Aspergillus fumigatus","year":2019,"lang":"en","type":"article","venue":"Biomolecular NMR Assignments","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","keywords":"Mucor circinelloides; Aspergillus fumigatus; Mucor; Aspergillus; Microbiology; Filamentous fungus; Fungal protein; Biology; Biochemistry; Enzyme; Yeast; Saccharomyces cerevisiae","score_opus":0.007661802574597965,"score_gpt":0.22080851883756245,"score_spread":0.21314671626296447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2911884050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.975972,0.005059141,0.009452743,0.0005128021,0.00014525221,0.000027095348,0.0022424157,0.00020077828,0.0063878954],"genre_scores_gemma":[0.97463226,0.0037751705,0.011838839,0.0002314792,0.00006526742,0.000056432884,0.004861987,0.000071400325,0.004467151],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99986506,0.000018868206,0.000008518594,0.000029887551,0.000045571203,0.000032155673],"domain_scores_gemma":[0.99964213,0.000048175225,0.00010321011,0.00003442278,0.000105865845,0.00006619112],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002277528,0.00043938763,0.00020562022,0.0005360559,0.00047872856,0.00013957564,0.00052823714,0.00037650077,0.0027653382],"category_scores_gemma":[0.0003766282,0.00015845858,0.000194328,0.0008237958,0.00031113924,0.00029215225,0.00024541627,0.00047107512,0.0003158296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034994882,0.000028114739,0.00078412856,0.00018727838,0.00002419402,0.00028649287,0.00015714062,0.0003903304,0.9908261,0.0002063149,0.0005799318,0.0061800014],"study_design_scores_gemma":[0.00011270614,0.00091183174,0.06372408,0.00010861402,0.00017367152,0.0026492884,0.0008571583,0.0077257706,0.89947736,0.00071987923,0.023409925,0.00012959106],"about_ca_topic_score_codex":0.0044814716,"about_ca_topic_score_gemma":0.004400629,"teacher_disagreement_score":0.0044814716,"about_ca_system_score_codex":0.00036535916,"about_ca_system_score_gemma":0.00024967847,"threshold_uncertainty_score":0.009250939},"labels":[],"label_agreement":null},{"id":"W2912001981","doi":"10.1107/s010876731809877x","title":"Structural characterization of the <i>Helicobacter pylori</i> peptidyl-prolyl <i>cis</i>,<i>trans</i>-isomerase HP0175 reveals an extension of chaperone helices upon target interaction","year":2018,"lang":"en","type":"article","venue":"Acta Crystallographica Section A Foundations and Advances","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Isomerase; Helicobacter pylori; Chaperone (clinical); Chemistry; Stereochemistry; Biochemistry; Crystallography; Biology; Genetics; Enzyme; Medicine","score_opus":0.011831231632872316,"score_gpt":0.26170082746720646,"score_spread":0.24986959583433416,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2912001981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9964007,0.0008223676,0.000692125,0.00009258944,0.000016585687,0.0000088548495,0.00068863516,0.00003642991,0.001241737],"genre_scores_gemma":[0.98936486,0.0011180814,0.0023687845,0.00006734891,0.00001546933,0.00001128976,0.0057725455,0.000037742117,0.0012437807],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993956,0.0000071781246,0.000003384316,0.000010258995,0.00002598296,0.000013653604],"domain_scores_gemma":[0.99987733,0.000019422581,0.00003824444,0.0000069061953,0.000023294855,0.000034805857],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010326122,0.00032517657,0.00020514964,0.00015345597,0.00017278643,0.00026406458,0.00041882423,0.00029051738,0.0011276948],"category_scores_gemma":[0.00024204007,0.00017405572,0.00024774752,0.0003004754,0.00018340662,0.0001743607,0.00012833439,0.00039287796,0.0003106348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006788178,0.00013380249,0.0071388953,0.00026547725,0.00004567673,0.0010272517,0.00014308166,0.0021694314,0.978277,0.0005757861,0.0010602862,0.008484374],"study_design_scores_gemma":[0.00025728636,0.00216523,0.26261827,0.00012424636,0.00025883413,0.005258404,0.0011320385,0.03898604,0.65345806,0.000784111,0.03481678,0.00014060576],"about_ca_topic_score_codex":0.0068360134,"about_ca_topic_score_gemma":0.004642476,"teacher_disagreement_score":0.0068360134,"about_ca_system_score_codex":0.00063653203,"about_ca_system_score_gemma":0.0003595566,"threshold_uncertainty_score":0.013592482},"labels":[],"label_agreement":null},{"id":"W2913508461","doi":"10.1038/s41419-019-1316-8","title":"Ser46 phosphorylation of p53 is an essential event in prolyl-isomerase Pin1-mediated p53-independent apoptosis in response to heat stress","year":2019,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"PIN1; Prolyl isomerase; Phosphorylation; Cell biology; Biology; Peptidylprolyl isomerase; Apoptosis; Mitochondrion; Signal transduction; Reactive oxygen species; Context (archaeology); Transcription factor; Mediator; Cancer research; Biochemistry; Isomerase; Gene","score_opus":0.006482185021590343,"score_gpt":0.24010880262614107,"score_spread":0.23362661760455072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2913508461","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98910004,0.0053175315,0.003268914,0.00021638628,0.00007160401,0.00003229302,0.00033284893,0.00005661902,0.0016036412],"genre_scores_gemma":[0.99681264,0.0012261008,0.0006298495,0.00004187332,0.000011327333,0.000019219147,0.00026354234,0.0000045889856,0.000990872],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998888,0.000020263544,0.000009820195,0.000024126379,0.000022754644,0.000034321907],"domain_scores_gemma":[0.9999286,0.000006679887,0.000027614504,0.000006800187,0.000008837665,0.000021481128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001277872,0.00031272077,0.0001670612,0.000247868,0.00025024117,0.0001997419,0.00010431415,0.00020225706,0.0017192904],"category_scores_gemma":[0.0001480704,0.00011416668,0.00026682872,0.00013242656,0.00018980606,0.00028828825,0.0001966803,0.00039809544,0.0003328685],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00046089833,0.000029875398,0.00056551927,0.00007575243,0.000009406917,0.00027126435,0.000023577242,0.00004945644,0.996682,0.00013398755,0.000061604085,0.0016365935],"study_design_scores_gemma":[0.00003194412,0.00036581839,0.033864148,0.00001517828,0.000022913428,0.0011276492,0.000058669284,0.0008969511,0.9611726,0.00026268634,0.0021731385,0.000008344501],"about_ca_topic_score_codex":0.0002567079,"about_ca_topic_score_gemma":0.00031750635,"teacher_disagreement_score":0.0017192904,"about_ca_system_score_codex":0.00018197283,"about_ca_system_score_gemma":0.00011483423,"threshold_uncertainty_score":0.00575161},"labels":[],"label_agreement":null},{"id":"W2914708865","doi":"10.1111/jnc.14683","title":"Pink1 regulates <scp>FKBP</scp>5 interaction with <scp>AKT</scp>/<scp>PHLPP</scp> and protects neurons from neurotoxin stress induced by <scp>MPP</scp><sup>+</sup>","year":2019,"lang":"en","type":"article","venue":"Journal of Neurochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hotchkiss Brain Institute; University of Calgary; University of Ottawa","funders":"Canadian Institutes of Health Research; Krembil Foundation","keywords":"Protein kinase B; PINK1; Cell biology; Phosphatase; Kinase; Phosphorylation; Biology; Chemistry; Protein kinase A; Molecular biology; Biochemistry","score_opus":0.008867048265832704,"score_gpt":0.22413908831441567,"score_spread":0.21527204004858297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2914708865","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952809,0.00089689466,0.0017303503,0.00012734885,0.000021104632,0.000013541969,0.0008724071,0.00009205782,0.00096525415],"genre_scores_gemma":[0.9951645,0.00039787331,0.0010398004,0.000045085613,0.000004269147,0.00002328173,0.0007325488,0.000026577922,0.0025659925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985874,0.00001724446,0.000013580766,0.000030410032,0.00003970439,0.00004029985],"domain_scores_gemma":[0.9999006,0.00001005049,0.000038203227,0.00000900337,0.000008245136,0.000033893084],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000094906565,0.00041672465,0.00017937431,0.00023440497,0.00030425627,0.0003346877,0.00022611527,0.00021723393,0.0018302335],"category_scores_gemma":[0.00008304976,0.0001644286,0.00022158555,0.00015779184,0.00030046853,0.00017979949,0.00019693043,0.00045859392,0.00069944916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006724807,0.000009802407,0.00011897307,0.000021061185,0.0000041651847,0.000028768869,0.00000674627,0.00004115381,0.99939954,0.00006157038,0.000034998808,0.00020605694],"study_design_scores_gemma":[0.000009026077,0.00004987891,0.0064463033,0.0000046106984,0.000011683432,0.0001287671,0.000021109025,0.00076215924,0.991433,0.000029617706,0.001100899,0.0000029170665],"about_ca_topic_score_codex":0.0022131852,"about_ca_topic_score_gemma":0.0039078738,"teacher_disagreement_score":0.0022131852,"about_ca_system_score_codex":0.000727732,"about_ca_system_score_gemma":0.0002670784,"threshold_uncertainty_score":0.0061227083},"labels":[],"label_agreement":null},{"id":"W2918072999","doi":"","title":"Myocyte enhancer factor 2 (MEF2) : un facteur impliqué dans le maintien des fonctions stéroïdogéniques des cellules de Leydig","year":2015,"lang":"fr","type":"dissertation","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; University of Ottawa","keywords":"Mef2; Molecular biology; Biology; Cell biology; Chemistry; Enhancer; Transcription factor; Genetics","score_opus":0.018256748493774087,"score_gpt":0.2815390060280961,"score_spread":0.26328225753432205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2918072999","genre_codex":"empirical","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8976009,0.064293295,0.020250386,0.0018911796,0.00072547776,0.00007458181,0.0015184734,0.00037896508,0.013266844],"genre_scores_gemma":[0.9498031,0.015977304,0.011467299,0.00090649026,0.0002514435,0.000095207375,0.001185772,0.00005844221,0.020254908],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981195,0.000026439067,0.000008954799,0.00007100141,0.000050466897,0.000031321808],"domain_scores_gemma":[0.99980944,0.000056687444,0.00003964644,0.000017895938,0.000043006425,0.000033246863],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038527223,0.00033814844,0.00025626333,0.0005039962,0.00045023017,0.0006440053,0.00020949761,0.0007344888,0.0018434788],"category_scores_gemma":[0.00030670592,0.00017344455,0.00029767083,0.0002951709,0.00040903038,0.00042531436,0.00026769278,0.00051056634,0.0004507259],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027711538,0.000044651875,0.013682192,0.00037572312,0.000049624763,0.0004743384,0.00021065005,0.00019899014,0.9516219,0.0012547782,0.0008373492,0.030972686],"study_design_scores_gemma":[0.000071623974,0.00056701206,0.15096927,0.0002462659,0.00015124741,0.0034394942,0.0005141926,0.0016702778,0.7308166,0.0011825155,0.11030123,0.00007032048],"about_ca_topic_score_codex":0.001825055,"about_ca_topic_score_gemma":0.002559014,"teacher_disagreement_score":0.0018434788,"about_ca_system_score_codex":0.00032248785,"about_ca_system_score_gemma":0.00033820604,"threshold_uncertainty_score":0.006167054},"labels":[],"label_agreement":null},{"id":"W2943635746","doi":"10.1186/s12885-019-5500-0","title":"FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4","year":2019,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Manchester Biomedical Research Centre; Queen's University Belfast; Medical Research Council; Public Health Agency; National Institute for Health and Care Research; Queen's University; Cancer Research UK","keywords":"Breast cancer; Metastasis; Medicine; Cancer; Cancer research; Cancer stem cell; Surgical oncology; Triple-negative breast cancer; CA15-3; Internal medicine; Metastatic breast cancer; Cancer cell; In vivo; Targeted therapy; Oncology; Biology","score_opus":0.016971937322031453,"score_gpt":0.2663999447202461,"score_spread":0.24942800739821464,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2943635746","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99549896,0.0018735809,0.0008431266,0.00011282437,0.000025232832,0.000036436253,0.00021432775,0.000045501685,0.0013498545],"genre_scores_gemma":[0.99586844,0.0009705227,0.0010069391,0.00004101161,0.000008350566,0.00003420856,0.0003052962,0.000006355314,0.001759068],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994016,0.000008838786,0.0000075594357,0.000008809568,0.0000174277,0.000017233631],"domain_scores_gemma":[0.99995685,0.000010163427,0.000013656314,0.0000036389113,0.000005758706,0.000009865905],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008516009,0.00021010294,0.000179883,0.00016512447,0.00007693944,0.00015406002,0.00013475677,0.00016643744,0.0014463472],"category_scores_gemma":[0.00008675441,0.000051694344,0.00011973163,0.000097299315,0.00014746706,0.000123554,0.00008510424,0.00034121564,0.00028515776],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037344155,0.00011749437,0.00023508792,0.00010964491,0.000009183686,0.000047789075,0.00001720428,0.0001982087,0.9919018,0.00006927007,0.00013184118,0.006788995],"study_design_scores_gemma":[0.00010235004,0.002617893,0.0037183482,0.000009913603,0.000031448093,0.00037824546,0.000025829151,0.000558747,0.9885854,0.000023867065,0.0039421823,0.0000058480114],"about_ca_topic_score_codex":0.0005329608,"about_ca_topic_score_gemma":0.0009738874,"teacher_disagreement_score":0.0014463472,"about_ca_system_score_codex":0.00023170897,"about_ca_system_score_gemma":0.00016242125,"threshold_uncertainty_score":0.0048384666},"labels":[],"label_agreement":null},{"id":"W2944662665","doi":"10.1007/s00018-019-03130-4","title":"Listeria monocytogenes hijacks CD147 to ensure proper membrane protrusion formation and efficient bacterial dissemination","year":2019,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Listeria monocytogenes; Cell biology; Ezrin; Biology; Cypa; Cell membrane; Cell; Actin; Microbiology; Bacteria; Cyclophilin A; Cytoskeleton; Molecular biology; Biochemistry; Genetics","score_opus":0.01099163008486991,"score_gpt":0.25067383608696137,"score_spread":0.23968220600209145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2944662665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98944366,0.0017762971,0.0054667206,0.00051495247,0.0000794458,0.000021549557,0.00018558683,0.00018143456,0.0023303304],"genre_scores_gemma":[0.99453545,0.00027078137,0.0024888208,0.00013242732,0.000017427932,0.000015355781,0.0002533657,0.000015817048,0.0022705426],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997317,0.000027580407,0.00002291163,0.000035140965,0.00006209268,0.00012062952],"domain_scores_gemma":[0.9998323,0.00001471886,0.00004389792,0.000023708268,0.00003536586,0.000050055314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018899502,0.00023556734,0.0001889936,0.00017465571,0.00015021164,0.0005956923,0.00015708373,0.0005084632,0.0009907141],"category_scores_gemma":[0.0002430671,0.00017177944,0.0002217445,0.000073793235,0.00016676071,0.00036637645,0.00061620056,0.0006873263,0.0007840743],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015487088,0.000022749386,0.0009422909,0.000031282794,0.0000051039174,0.00010848127,0.000014987606,0.000063578285,0.9956208,0.00029822835,0.00021153204,0.0025260276],"study_design_scores_gemma":[0.00004110786,0.00030263947,0.015647357,0.000019988704,0.000014727815,0.0006887217,0.00010851116,0.0034822358,0.97335976,0.0003024421,0.0060220337,0.000010566861],"about_ca_topic_score_codex":0.00020480645,"about_ca_topic_score_gemma":0.00034997868,"teacher_disagreement_score":0.0009907141,"about_ca_system_score_codex":0.00036910584,"about_ca_system_score_gemma":0.00029974178,"threshold_uncertainty_score":0.0033142567},"labels":[],"label_agreement":null},{"id":"W2945912122","doi":"10.1158/1538-7445.am2017-1583","title":"Abstract 1583: Inhibition of proline isomerase Pin1 interrupts the function of the androgen receptor N-terminal domain and suppresses androgen-independent growth of prostate cancer cells","year":2017,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Transactivation; PIN1; Androgen receptor; Prostate cancer; Peptidylprolyl isomerase; Cancer research; Dihydrotestosterone; Transcription factor; Androgen; Biology; Chemistry; Endocrinology; Cancer; Isomerase; Biochemistry; Gene; Genetics; Hormone","score_opus":0.03385072101828961,"score_gpt":0.3413013503711698,"score_spread":0.3074506293528802,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2945912122","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9912111,0.0027274697,0.001744746,0.0001987441,0.00012309132,0.000059160255,0.0008631395,0.00018017214,0.0028922737],"genre_scores_gemma":[0.9925922,0.000998975,0.0010356638,0.000098668104,0.000022527132,0.00006198783,0.0015016972,0.000027886488,0.003660398],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998661,0.00001783065,0.000010681023,0.00002032843,0.000038123588,0.000046824174],"domain_scores_gemma":[0.9999386,0.00001219561,0.000013582395,0.0000059869644,0.0000050431786,0.000024560039],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000098225486,0.00047992583,0.0003210323,0.00017287789,0.00015235099,0.00025119612,0.00033678836,0.00023833461,0.0031591575],"category_scores_gemma":[0.00009213682,0.00014277302,0.00029925205,0.00014322954,0.00024125143,0.00014093456,0.00017967782,0.0008265269,0.0008509658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00049725344,0.00017548857,0.0001390988,0.000077800956,0.000012908281,0.00007790669,0.000007860781,0.00012353959,0.99689144,0.0001117182,0.00020403796,0.0016809598],"study_design_scores_gemma":[0.00008530024,0.0011775077,0.0028296444,0.000007851054,0.000018660654,0.00027737988,0.00001736495,0.0009578946,0.99166274,0.000032439897,0.0029287112,0.0000044052895],"about_ca_topic_score_codex":0.0004250653,"about_ca_topic_score_gemma":0.0005829189,"teacher_disagreement_score":0.0031591575,"about_ca_system_score_codex":0.00028833057,"about_ca_system_score_gemma":0.00030478006,"threshold_uncertainty_score":0.01056844},"labels":[],"label_agreement":null},{"id":"W2950485525","doi":"10.1101/632547","title":"Systematic discovery of Short Linear Motifs decodes calcineurin phosphatase signaling","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; Institute of Cancer Research; University of Toronto; Mount Sinai Hospital","funders":"Carl Tryggers Stiftelse för Vetenskaplig Forskning; National Institutes of Health; Vetenskapsrådet; Science Foundation Ireland; Canadian Institutes of Health Research; Ontario Genomics; Genome Canada","keywords":"Calcineurin; In silico; Phosphatase; Proteome; Interactome; Biology; Computational biology; Cell biology; Nuclear transport; Biochemistry; Phosphorylation; Gene; Cell nucleus","score_opus":0.012982908264073962,"score_gpt":0.2354606221791613,"score_spread":0.22247771391508733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950485525","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9446275,0.0006110806,0.051387135,0.00019664645,0.000025156487,0.000059236976,0.0006741641,0.0005727488,0.0018462734],"genre_scores_gemma":[0.955634,0.0005196441,0.042148903,0.00005785531,0.000007739205,0.000034873236,0.00096044963,0.00011354971,0.00052305066],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9998796,0.000021322287,0.00000836366,0.00003945007,0.000035866644,0.000015376523],"domain_scores_gemma":[0.9997689,0.000098623445,0.0000591421,0.000027828075,0.000022529695,0.00002297173],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037149186,0.00033952115,0.00032086857,0.00024063187,0.0001578546,0.000591584,0.00026434922,0.00021845002,0.0006768036],"category_scores_gemma":[0.0006206512,0.00023710568,0.00026614298,0.00023737576,0.00024995167,0.00029409592,0.0003065054,0.0005367315,0.00026096904],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003793458,0.00006935109,0.00563258,0.00027121068,0.00006308156,0.00023077798,0.00005265944,0.023439512,0.9465784,0.0049802167,0.00037471362,0.017928226],"study_design_scores_gemma":[0.000032423708,0.00019141386,0.0028375082,0.000019845806,0.000056968962,0.00013427684,0.00005351626,0.19625753,0.7933185,0.00382695,0.0032525542,0.000018488765],"about_ca_topic_score_codex":0.00059724425,"about_ca_topic_score_gemma":0.001352369,"teacher_disagreement_score":0.0006768036,"about_ca_system_score_codex":0.00046450386,"about_ca_system_score_gemma":0.00047690186,"threshold_uncertainty_score":0.0033701658},"labels":[],"label_agreement":null},{"id":"W2952609089","doi":"10.1007/s13346-019-00651-0","title":"Liposomal OTS964, a TOPK inhibitor: a simple method to estimate OTS964 association with liposomes that relies on enhanced OTS964 fluorescence when bound to albumin","year":2019,"lang":"en","type":"article","venue":"Drug Delivery and Translational Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Simon Fraser University; BC Cancer Agency","funders":"Canadian Institutes of Health Research; Deutsche Forschungsgemeinschaft","keywords":"Liposome; Chemistry; Fluorescence; Albumin; Pharmacology; Absorbance; Biochemistry; Biophysics; Chromatography; Biology","score_opus":0.023739097631854108,"score_gpt":0.3409061079970536,"score_spread":0.3171670103651995,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952609089","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.807809,0.0033705235,0.182736,0.00038087618,0.00012968297,0.00040441804,0.00083759363,0.0007432844,0.0035885826],"genre_scores_gemma":[0.8931365,0.0016263422,0.095862046,0.00015298928,0.000029902372,0.00036937388,0.0010342512,0.00017145429,0.0076171244],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995797,0.000079530495,0.000033394157,0.00009505962,0.00014259569,0.000069688125],"domain_scores_gemma":[0.9997931,0.000047703707,0.00005473598,0.000027207516,0.00004037406,0.000036826303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00049605744,0.0008292833,0.00036883462,0.00041253612,0.00031278306,0.00048745112,0.00048906443,0.00065035245,0.0011707519],"category_scores_gemma":[0.00051835336,0.00030721922,0.00026050044,0.00028565899,0.00035979477,0.00052870763,0.00050977495,0.0011036578,0.0005177196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010332199,0.000014970889,0.00015184382,0.000038525224,0.000011609201,0.000017769304,0.000015092293,0.00007814364,0.9975937,0.00007962866,0.000051455103,0.0018438471],"study_design_scores_gemma":[0.000010725019,0.000053615793,0.0006457048,0.0000036188537,0.000013059389,0.00005731945,0.0000091945285,0.0015953806,0.9966839,0.000037626953,0.0008815828,0.000008263661],"about_ca_topic_score_codex":0.0011606528,"about_ca_topic_score_gemma":0.0012406684,"teacher_disagreement_score":0.0011707519,"about_ca_system_score_codex":0.00052446383,"about_ca_system_score_gemma":0.00044830877,"threshold_uncertainty_score":0.0039165616},"labels":[],"label_agreement":null},{"id":"W2953123068","doi":"10.1016/j.oooo.2019.06.005","title":"Cyclooxygenase and CD147 expression in oral squamous cell carcinoma patient samples and cell lines","year":2019,"lang":"en","type":"article","venue":"Oral Surgery Oral Medicine Oral Pathology and Oral Radiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health PEI; University of Prince Edward Island","funders":"","keywords":"Medicine; Cyclooxygenase; Basal cell; Cancer research; Cell; Oncology; Cell culture; Internal medicine; Enzyme; Biochemistry","score_opus":0.01783000825100487,"score_gpt":0.24431651929167036,"score_spread":0.2264865110406655,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953123068","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9954265,0.0014400263,0.0006536036,0.00003495011,0.000017303128,0.00009626073,0.0011306647,0.000022056513,0.0011787168],"genre_scores_gemma":[0.9935464,0.00080724683,0.0012844311,0.000050722345,0.000017000928,0.00019253179,0.0032715332,0.000007446595,0.0008226598],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997745,0.000036120688,0.000029704443,0.000045788194,0.00007437929,0.000039555965],"domain_scores_gemma":[0.9997961,0.000062325154,0.000032068536,0.00003284236,0.000054361793,0.00002230055],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031899338,0.00015772236,0.00028522,0.0005171793,0.00025729233,0.00036539003,0.00017364412,0.0002837854,0.0018589657],"category_scores_gemma":[0.00057269225,0.00010357057,0.00014172602,0.00058066007,0.00020999539,0.00011927081,0.00015020906,0.00016941447,0.0005046437],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003826355,0.00052766694,0.5255901,0.00053911825,0.0001287517,0.0036930009,0.00082329405,0.00040254465,0.43170074,0.00028424402,0.001683813,0.03080042],"study_design_scores_gemma":[0.00022421878,0.0024989534,0.7858895,0.000056851535,0.00024076254,0.018803531,0.0015707164,0.0014312696,0.17499392,0.00016319484,0.014098192,0.00002887356],"about_ca_topic_score_codex":0.00086519745,"about_ca_topic_score_gemma":0.0010578905,"teacher_disagreement_score":0.0018589657,"about_ca_system_score_codex":0.00018461286,"about_ca_system_score_gemma":0.00023795951,"threshold_uncertainty_score":0.00621891},"labels":[],"label_agreement":null},{"id":"W2954482364","doi":"10.1158/1538-7445.sabcs18-1023","title":"Abstract 1023: Combining all-trans retinoic acid therapy with androgen receptor N-terminal domain inhibitors for the treatment of castration-resistant prostate cancer","year":2019,"lang":"en","type":"article","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Androgen receptor; Transactivation; Prostate cancer; LNCaP; Bicalutamide; Cancer research; Androgen deprivation therapy; Biology; Dihydrotestosterone; Signal transduction; Endocrinology; Chemistry; Androgen; Internal medicine; Cancer; Cell biology; Medicine; Transcription factor; Biochemistry; Gene; Hormone","score_opus":0.01652830879227166,"score_gpt":0.2724339506172784,"score_spread":0.2559056418250067,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2954482364","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9685177,0.013838977,0.0028705683,0.00044581448,0.00020463315,0.0005998755,0.000794734,0.0002476562,0.012480102],"genre_scores_gemma":[0.9852314,0.004200581,0.002841337,0.00021900353,0.000031122214,0.00013162744,0.00064866274,0.00002090991,0.0066753183],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993944,0.000013016101,0.0000044332673,0.00000750617,0.000016988519,0.00001854032],"domain_scores_gemma":[0.99997616,0.0000024563055,0.0000048465718,0.0000023751022,0.0000026661012,0.000011458545],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001358682,0.00035454956,0.0003887387,0.00023251162,0.00014389868,0.00025896632,0.0003076366,0.00025672553,0.002779003],"category_scores_gemma":[0.00004876636,0.000092592534,0.00028337445,0.00016165874,0.00014402717,0.00016009547,0.00012485834,0.0006267142,0.00060665567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.005443536,0.0030159224,0.0007494827,0.00045003413,0.00012711446,0.00032882087,0.00005411228,0.0009739733,0.8941489,0.00078824523,0.0016366984,0.09228322],"study_design_scores_gemma":[0.0045121936,0.061370898,0.014832606,0.00008031092,0.0003366011,0.0025359653,0.0000912243,0.0034455757,0.87243736,0.0003290321,0.039982684,0.000045677294],"about_ca_topic_score_codex":0.00070704875,"about_ca_topic_score_gemma":0.0024661452,"teacher_disagreement_score":0.002779003,"about_ca_system_score_codex":0.00022498862,"about_ca_system_score_gemma":0.00040676267,"threshold_uncertainty_score":0.009296715},"labels":[],"label_agreement":null},{"id":"W2963506962","doi":"10.1139/cjpp-2019-0142","title":"Role of Brd4 in the production of inflammatory cytokines in mouse macrophages treated with titanium particles","year":2019,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Qingdao University; Natural Science Foundation of Shandong Province; National Natural Science Foundation of China","keywords":"Cytokine; Inflammation; Chemistry; Cell biology; Downregulation and upregulation; Macrophage; BRD4; Acetylation; NF-κB; Cancer research; Molecular biology; Immunology; Biology; Biochemistry; In vitro","score_opus":0.005614780034057908,"score_gpt":0.22322516052116317,"score_spread":0.21761038048710526,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2963506962","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97770077,0.010321658,0.0072578494,0.0006177414,0.0002596559,0.00011371959,0.0012983477,0.00020111147,0.0022290011],"genre_scores_gemma":[0.9836179,0.0034384762,0.0044844067,0.0004365562,0.000050355746,0.00032416618,0.0015461402,0.000053103402,0.0060490062],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99936193,0.00008637182,0.00007501853,0.00012938672,0.00017287063,0.00017439386],"domain_scores_gemma":[0.9998221,0.0000151649465,0.00005346305,0.000017958364,0.00003737152,0.000053902353],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00041767457,0.00055103714,0.00069895375,0.0008520644,0.00036464602,0.00038310257,0.00035344635,0.00084741355,0.0021641345],"category_scores_gemma":[0.00020168434,0.00039893744,0.0010647633,0.0003498921,0.00051013095,0.0004824012,0.0004131349,0.0012018969,0.00071495236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004493562,0.00005203181,0.0002933993,0.00015322767,0.000009433994,0.00006874904,0.000029501356,0.000029365778,0.9981591,0.00004469329,0.000047257097,0.00066390785],"study_design_scores_gemma":[0.00009869847,0.00065672,0.00799543,0.000025972986,0.00005541691,0.00026682764,0.00014640985,0.0006830322,0.9873351,0.00009924185,0.002622552,0.000014481353],"about_ca_topic_score_codex":0.000657372,"about_ca_topic_score_gemma":0.00065803673,"teacher_disagreement_score":0.0021641345,"about_ca_system_score_codex":0.00044486078,"about_ca_system_score_gemma":0.00034593255,"threshold_uncertainty_score":0.0072396994},"labels":[],"label_agreement":null},{"id":"W2970446701","doi":"10.1038/s41380-019-0487-0","title":"Regulator of calcineurin 1 is a novel RNA-binding protein to regulate neuronal apoptosis","year":2019,"lang":"en","type":"article","venue":"Molecular Psychiatry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China; Government of Canada","keywords":"RNA-binding protein; Biology; Cell biology; RNA; Neurodegeneration; Gene; Biochemistry","score_opus":0.0067738996527845685,"score_gpt":0.23517539388803937,"score_spread":0.2284014942352548,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2970446701","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94093525,0.02250784,0.02090033,0.00110107,0.00054390676,0.00014690254,0.0007834757,0.0007117268,0.012369502],"genre_scores_gemma":[0.9818363,0.0022101018,0.0070351455,0.00038682492,0.00009686425,0.00005912435,0.000830435,0.000043944194,0.0075012106],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983764,0.000018846502,0.000007641097,0.000050318155,0.000062281695,0.00002325868],"domain_scores_gemma":[0.9998896,0.000018823952,0.000026253727,0.000009649368,0.000021544216,0.00003406926],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020196798,0.0004551395,0.00023896377,0.0005208297,0.0007840179,0.00040461263,0.0005135924,0.0004679501,0.0014056868],"category_scores_gemma":[0.00021627724,0.00016246756,0.0003718329,0.00018739281,0.00028291607,0.00020848932,0.00021774697,0.00073883927,0.0003644797],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012568926,0.000033263044,0.00059102534,0.000043245345,0.000016389256,0.00083959504,0.000023994968,0.00017381515,0.9932748,0.0009753127,0.00032291358,0.0035800608],"study_design_scores_gemma":[0.00008535132,0.00034036633,0.0247982,0.000024202069,0.00007808166,0.004932655,0.00006599001,0.005881771,0.94340277,0.0011105296,0.019249478,0.000030592473],"about_ca_topic_score_codex":0.0011322793,"about_ca_topic_score_gemma":0.0019382411,"teacher_disagreement_score":0.0014056868,"about_ca_system_score_codex":0.0008459392,"about_ca_system_score_gemma":0.0003913465,"threshold_uncertainty_score":0.0061377287},"labels":[],"label_agreement":null},{"id":"W2973136559","doi":"10.1016/j.molmet.2019.09.003","title":"Focus on FKBP51: A molecular link between stress and metabolic disorders","year":2019,"lang":"en","type":"review","venue":"Molecular Metabolism","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":76,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Bundesministerium für Bildung und Forschung","keywords":"Focus (optics); Link (geometry); Computational biology; Stress (linguistics); Bioinformatics; Biology; Medicine; Computer science; Physics","score_opus":0.020615290861362233,"score_gpt":0.2963721725972939,"score_spread":0.2757568817359317,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2973136559","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016133151,0.9977641,0.00013609543,0.0006561258,0.0004056253,0.0000025057454,0.000016826527,0.000007412768,0.000849949],"genre_scores_gemma":[0.0013870299,0.9966955,0.00016034133,0.0004800556,0.00038288027,0.000005012595,0.000039411472,0.0000017054365,0.0008480114],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998666,0.00002432708,0.000022267184,0.000030699273,0.00003545586,0.00002061842],"domain_scores_gemma":[0.99969697,0.00016083,0.000041146748,0.000006797872,0.000070238246,0.000024109424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003648197,0.0007321579,0.00093779207,0.0015706612,0.0003136329,0.00079649844,0.00052916794,0.0010749476,0.0037809252],"category_scores_gemma":[0.00060936797,0.00018523281,0.0004631476,0.0013982534,0.00040038943,0.0010988954,0.00057862315,0.0017972968,0.0014827154],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016951362,0.000050991417,0.0003307496,0.022875763,0.00015448718,0.00044663847,0.0001129051,0.00040580655,0.004246678,0.006921318,0.04895161,0.9153335],"study_design_scores_gemma":[0.000018760167,0.00012729096,0.0017632826,0.0054266513,0.0002152264,0.0026202598,0.000089084104,0.000126687,0.00094340503,0.0032888104,0.9853579,0.000022793907],"about_ca_topic_score_codex":0.00095008075,"about_ca_topic_score_gemma":0.0014757231,"teacher_disagreement_score":0.0037809252,"about_ca_system_score_codex":0.0007192663,"about_ca_system_score_gemma":0.001164179,"threshold_uncertainty_score":0.012648463},"labels":[],"label_agreement":null},{"id":"W2973294764","doi":"10.1038/s41467-019-12199-1","title":"Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents","year":2019,"lang":"en","type":"article","venue":"Nature Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":126,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Research Council Canada; Western Economic Diversification Canada; Canadian Institutes of Health Research; Office of Science; Michigan Technology Tri-Corridor; Astellas Pharma; University of Saskatchewan; Ministry of Trade, Industry and Energy; Natural Sciences and Engineering Research Council of Canada; Canadian Light Source; Amplyx; Astellas Pharma Global Development; National Institutes of Health; Michigan Economic Development Corporation; U.S. Department of Health and Human Services; Argonne National Laboratory; U.S. Department of Energy","keywords":"Calcineurin; Cryptococcus neoformans; Aspergillus fumigatus; FKBP; Candida albicans; Cryptococcosis; Biology; Coccidioides immitis; Microbiology; Virulence; Fungal protein; Echinocandins; Antifungal drug; Cryptococcus; Peptidylprolyl isomerase; Antifungal; Biochemistry; Fluconazole; Saccharomyces cerevisiae; Yeast; Medicine; Transplantation; Enzyme","score_opus":0.021870468467737467,"score_gpt":0.298897820951989,"score_spread":0.27702735248425153,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2973294764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9789972,0.0015078845,0.011351914,0.00084782037,0.00011052136,0.00006243415,0.0014096125,0.00048440785,0.0052282005],"genre_scores_gemma":[0.9679987,0.0019563024,0.023034692,0.00016940139,0.000021041278,0.00009416692,0.004506987,0.00013670899,0.002082027],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991477,0.000011257667,0.000003936883,0.000011512146,0.000041059157,0.000017550812],"domain_scores_gemma":[0.99987435,0.000039544222,0.000017949234,0.000007752361,0.00003650218,0.000023917744],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017240939,0.00030460925,0.00036151783,0.00018744839,0.0005510981,0.0004819636,0.00056891417,0.00038087467,0.0021030828],"category_scores_gemma":[0.00037780966,0.00022053592,0.00019586079,0.00032866572,0.00017758182,0.0003783507,0.0003396806,0.001121489,0.0002619979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011400351,0.0006550796,0.007357125,0.000828601,0.00018125471,0.0014174456,0.00094141025,0.028640337,0.9071839,0.0074364874,0.011553032,0.032665253],"study_design_scores_gemma":[0.0012413012,0.00072159746,0.029173102,0.00016091568,0.00022879237,0.0013291411,0.0013334661,0.37676635,0.5258588,0.0044127703,0.058659505,0.00011433243],"about_ca_topic_score_codex":0.008859075,"about_ca_topic_score_gemma":0.012960896,"teacher_disagreement_score":0.008859075,"about_ca_system_score_codex":0.0008187906,"about_ca_system_score_gemma":0.00077050057,"threshold_uncertainty_score":0.01761502},"labels":[],"label_agreement":null},{"id":"W2979154657","doi":"","title":"Solution NMR structure of human NFATC2IP ubiquitin-like domain, NFATC2IP_244_338, NESG target HT65A/OCSP target hs00387_244_338/SGC-toronto","year":2010,"lang":"","type":"paratext","venue":"Open MIND","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Domain (mathematical analysis); Chemistry; Ubiquitin; Biochemistry; Mathematics; Gene","score_opus":0.018244841632611117,"score_gpt":0.30490041648393357,"score_spread":0.2866555748513224,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2979154657","genre_codex":"empirical","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"dataset","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9113007,0.007636272,0.008078189,0.004156396,0.0004301513,0.0001374538,0.023588901,0.0010128275,0.043659117],"genre_scores_gemma":[0.863861,0.0065947636,0.013484458,0.00066304475,0.00015616385,0.00013629039,0.09072018,0.00027122707,0.024112925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993694,0.000005016591,0.0000028293075,0.00001481038,0.00002166784,0.000018705798],"domain_scores_gemma":[0.99988174,0.00003118884,0.000016107488,0.000007280625,0.000029897486,0.000033713208],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001766577,0.0006440811,0.0004333689,0.00024264543,0.00085163175,0.00044658175,0.0011282348,0.00066554185,0.009151241],"category_scores_gemma":[0.00038743587,0.00028258824,0.00028214918,0.0005666113,0.00020823322,0.00047616646,0.00022599199,0.0011650121,0.0015116833],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0044239773,0.00046967028,0.0033142767,0.0013961085,0.0001984189,0.0023993147,0.00085758255,0.012149034,0.8722648,0.004962011,0.07296478,0.024600107],"study_design_scores_gemma":[0.002359937,0.0019589528,0.086623,0.0003158073,0.00073305226,0.0032323725,0.0018622726,0.10127017,0.50655776,0.00391008,0.29066646,0.0005101644],"about_ca_topic_score_codex":0.015236025,"about_ca_topic_score_gemma":0.022039704,"teacher_disagreement_score":0.015236025,"about_ca_system_score_codex":0.0018391144,"about_ca_system_score_gemma":0.0008751775,"threshold_uncertainty_score":0.030613959},"labels":[],"label_agreement":null},{"id":"W2980031813","doi":"10.1016/j.chom.2019.08.004","title":"Calcium-Calmodulin-Calcineurin Signaling: A Globally Conserved Virulence Cascade in Eukaryotic Microbial Pathogens","year":2019,"lang":"en","type":"review","venue":"Cell Host & Microbe","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":187,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Korea Food Research Institute; National Research Foundation of Korea; Canadian Institute for Advanced Research; National Cancer Institute; National Institutes of Health; Max and Minnie Tomerlin Voelcker Fund","keywords":"Biology; Virulence; Calcineurin; Calmodulin; Calcium; Microbiology; Calcium signaling; Signal transduction; Pathogenicity; Cell biology; Biochemistry; Enzyme; Gene","score_opus":0.04258363763800245,"score_gpt":0.30215765011129336,"score_spread":0.2595740124732909,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2980031813","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00009981975,0.99826247,0.00017941203,0.00035861676,0.00033990492,0.0000031757036,0.000023997554,0.00000999831,0.00072248804],"genre_scores_gemma":[0.00059617346,0.9979773,0.00018175614,0.0002708334,0.00035136534,0.000004155007,0.000044332715,0.000001448995,0.00057259726],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998678,0.000014853317,0.0000154264,0.0000314103,0.00005073726,0.000019751034],"domain_scores_gemma":[0.99978155,0.000067880464,0.000039993367,0.0000062535332,0.0000642949,0.000040087954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005091019,0.0011171263,0.0012354008,0.001461384,0.00026195543,0.0013570609,0.000987248,0.0014017225,0.0024406547],"category_scores_gemma":[0.0004935697,0.00022893432,0.00030224695,0.0019459336,0.00056612625,0.0012451836,0.0009101597,0.0019525161,0.002560341],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015692611,0.00005112756,0.00014041917,0.010445866,0.000059849124,0.00018741965,0.000035124885,0.00034458947,0.0052558808,0.0049033617,0.04788136,0.9305382],"study_design_scores_gemma":[0.00002763199,0.000073750336,0.000724067,0.0017875357,0.000098362994,0.000658529,0.0000410869,0.00014586533,0.0008553427,0.002488845,0.9930813,0.00001779191],"about_ca_topic_score_codex":0.00083621853,"about_ca_topic_score_gemma":0.001580654,"teacher_disagreement_score":0.0024406547,"about_ca_system_score_codex":0.00084577076,"about_ca_system_score_gemma":0.0013654532,"threshold_uncertainty_score":0.008164823},"labels":[],"label_agreement":null},{"id":"W2981134148","doi":"10.1161/res.125.suppl_1.734","title":"Abstract 734: NF-kB Signaling Regulates Mitochondrial Permeability Transition Pore Opening of Cardiac Myocytes via Cyclophilin D (CypD) Modulation","year":2019,"lang":"en","type":"article","venue":"Circulation Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"","keywords":"Mitochondrial permeability transition pore; MPTP; Myocyte; Cell biology; IκB kinase; Programmed cell death; Mitochondrion; Biology; Signal transduction; NF-κB; Chemistry; Endocrinology; Apoptosis; Biochemistry","score_opus":0.03236418152779469,"score_gpt":0.3161472924769935,"score_spread":0.28378311094919884,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2981134148","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96665335,0.010856747,0.007426247,0.0012401714,0.0004966287,0.000099166355,0.0033815128,0.0003783492,0.009467783],"genre_scores_gemma":[0.9768554,0.0039793723,0.0016171563,0.00038099886,0.00010438094,0.00010696821,0.0026620019,0.000049580773,0.014244247],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992704,0.000008771986,0.0000073522738,0.000020024607,0.000017438642,0.000019337824],"domain_scores_gemma":[0.9999633,0.0000027717,0.000009697757,0.0000034639745,0.0000054433685,0.000015357968],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000072271774,0.00033994255,0.00019487685,0.00014207429,0.00022862632,0.00022794437,0.00017103841,0.00024402613,0.00592254],"category_scores_gemma":[0.0000555806,0.000095249736,0.0003080795,0.00014150482,0.00019825526,0.00017328007,0.00020596676,0.0005585369,0.0012796092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003394583,0.000028089353,0.00013001334,0.000115571995,0.0000060839147,0.00007806468,0.000008945965,0.00002486733,0.9971885,0.00010704892,0.0002960404,0.0016773008],"study_design_scores_gemma":[0.00010220594,0.00029220048,0.008515274,0.000019252686,0.00003636457,0.00043910273,0.000039288814,0.00044198675,0.9821958,0.000104335835,0.0078073577,0.0000068224253],"about_ca_topic_score_codex":0.00047296556,"about_ca_topic_score_gemma":0.00048679727,"teacher_disagreement_score":0.00592254,"about_ca_system_score_codex":0.00031951568,"about_ca_system_score_gemma":0.00023602799,"threshold_uncertainty_score":0.019812822},"labels":[],"label_agreement":null},{"id":"W2984142937","doi":"10.1038/s41467-019-13070-z","title":"Multiple conformations facilitate PilT function in the type IV pilus.","year":2019,"lang":"en","type":"paratext","venue":"PubMed","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; McMaster University; University of Toronto","funders":"Canada Research Chairs; Government of Canada","keywords":"Pilin; Pilus; Trimer; Chemistry; Crystallography; Protein structure; Mutant; Virulence; Biophysics; Biology; Biochemistry; Gene; Dimer","score_opus":0.03636455071082227,"score_gpt":0.23667100490725354,"score_spread":0.20030645419643128,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2984142937","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.73258567,0.0086064115,0.07461686,0.007625294,0.0013207791,0.0001823272,0.0053969016,0.0027631808,0.16690259],"genre_scores_gemma":[0.9609663,0.001705545,0.0086492775,0.00037734775,0.000062019426,0.000040672792,0.0037511727,0.000110943314,0.024336789],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998833,0.000021195168,0.000008728137,0.000022499074,0.000040623432,0.00002364431],"domain_scores_gemma":[0.9998229,0.00004995899,0.00003109897,0.00003203116,0.000022526357,0.00004145338],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018957457,0.0003622981,0.00021035149,0.00032437214,0.000490936,0.0009244908,0.00032601747,0.0005226815,0.018548053],"category_scores_gemma":[0.00052178523,0.00012432881,0.0002597876,0.00034728093,0.00034233212,0.0013118353,0.0006419732,0.00053644535,0.006268518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0012025003,0.00013731203,0.0075031053,0.0009262359,0.00003256831,0.003471956,0.000226639,0.004028869,0.80979127,0.08429471,0.018990127,0.069394834],"study_design_scores_gemma":[0.00014235737,0.00062980945,0.019379081,0.0002251258,0.00005529808,0.008772894,0.000978496,0.022805165,0.7418158,0.03983253,0.16526818,0.00009526954],"about_ca_topic_score_codex":0.00032339827,"about_ca_topic_score_gemma":0.00052678504,"teacher_disagreement_score":0.018548053,"about_ca_system_score_codex":0.00050718966,"about_ca_system_score_gemma":0.00029678163,"threshold_uncertainty_score":0.06204939},"labels":[],"label_agreement":null},{"id":"W2988318212","doi":"10.1038/s41598-019-50694-z","title":"CD109 acts as a gatekeeper of the epithelial trait by suppressing epithelial to mesenchymal transition in squamous cell carcinoma cells in vitro","year":2019,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; McGill University","funders":"CIHR Skin Research Training Centre; Canadian Institutes of Health Research; Jewish General Hospital; Government of Canada; McGill University","keywords":"Epithelial–mesenchymal transition; Phenotype; Biology; Mesenchymal stem cell; Cancer research; Signal transduction; Cell biology; Gene; Transition (genetics); Genetics","score_opus":0.005201287334897321,"score_gpt":0.2136869047844758,"score_spread":0.20848561744957847,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2988318212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9879794,0.0033076657,0.003157291,0.00031162248,0.000100102945,0.00005982587,0.0007383659,0.00015805112,0.0041876063],"genre_scores_gemma":[0.9919097,0.0013925807,0.0019421666,0.000099963756,0.000012672827,0.000056042725,0.0010150659,0.00002553537,0.0035464154],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997763,0.000046791665,0.000036036556,0.000034363897,0.00007180153,0.000034802873],"domain_scores_gemma":[0.99989367,0.000026545882,0.000017797687,0.00002472763,0.000012763361,0.000024565821],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016126293,0.00018759358,0.00032536726,0.00019692178,0.00021085331,0.00040578184,0.00018375952,0.00023063907,0.001673561],"category_scores_gemma":[0.00017964972,0.00011403764,0.00021855193,0.0002087714,0.0001804926,0.00015797882,0.00024452872,0.0006222288,0.0005991531],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000050426534,0.000029276911,0.00017148134,0.000032448082,0.0000044330827,0.00005720372,0.000009092626,0.00003834807,0.9984132,0.00004746853,0.00008345539,0.0010631575],"study_design_scores_gemma":[0.0000133958065,0.00012885565,0.0023128316,0.0000053374147,0.000011302217,0.00017577794,0.000025451436,0.0004561786,0.992605,0.000021736367,0.004241797,0.0000022634028],"about_ca_topic_score_codex":0.00077545084,"about_ca_topic_score_gemma":0.001058515,"teacher_disagreement_score":0.001673561,"about_ca_system_score_codex":0.00023133853,"about_ca_system_score_gemma":0.00025080293,"threshold_uncertainty_score":0.0055986047},"labels":[],"label_agreement":null},{"id":"W2991054518","doi":"10.1038/s41416-019-0649-5","title":"FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer","year":2019,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"BC Cancer Agency; Biotechnology and Biological Sciences Research Council; Almac Group; Almac Discovery; Medical Research Council; Department of Education and Learning, Northern Ireland","keywords":"Angiogenesis; Vasculogenic mimicry; Ovarian cancer; Cancer research; CD44; Cancer stem cell; Tissue microarray; Cancer; Immunohistochemistry; Medicine; Stem cell; Biology; Pathology; Cell; Internal medicine; Metastasis","score_opus":0.008069950884891174,"score_gpt":0.2466495777040419,"score_spread":0.2385796268191507,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2991054518","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9883354,0.008232664,0.0012200634,0.00026080964,0.000031000207,0.00006086413,0.00014283204,0.00006482828,0.0016515872],"genre_scores_gemma":[0.99659365,0.001672152,0.0008484142,0.00006325828,0.000018331302,0.000022029768,0.00014532066,0.0000043280056,0.0006324758],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993515,0.000012997401,0.000005221651,0.000008937662,0.000017743328,0.00001995138],"domain_scores_gemma":[0.9999443,0.000011985005,0.000019092933,0.0000033772326,0.0000064443107,0.000014805223],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014415536,0.00018560993,0.00015784647,0.00023940753,0.0001013892,0.00020787041,0.00011748965,0.00033464847,0.0009512134],"category_scores_gemma":[0.00010644673,0.000056852965,0.000092090966,0.00015970759,0.0002109064,0.000115821895,0.0001365924,0.00029893298,0.00025863224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071423483,0.00015114628,0.001514046,0.0003252987,0.000010473266,0.0002475974,0.000040119965,0.0005453753,0.9693625,0.0001635508,0.00034025562,0.026585378],"study_design_scores_gemma":[0.0005034395,0.009201061,0.02342702,0.000054870907,0.000081538135,0.0036665406,0.000095411335,0.0021555366,0.94304,0.00024694513,0.017511595,0.000016082906],"about_ca_topic_score_codex":0.00028079987,"about_ca_topic_score_gemma":0.00056687894,"teacher_disagreement_score":0.0009512134,"about_ca_system_score_codex":0.0002994647,"about_ca_system_score_gemma":0.00016607536,"threshold_uncertainty_score":0.0031821132},"labels":[],"label_agreement":null},{"id":"W2994351462","doi":"10.21769/bioprotoc.3449","title":"Proximity Ligation Assay for the Investigation of the Intramolecular Interaction of ELMO1","year":2019,"lang":"en","type":"article","venue":"BIO-PROTOCOL","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institut de Recherche Clinique De Montréal; Health and Medical Research Fund; Chinese University of Hong Kong","keywords":"Intramolecular force; Chemistry; Sf9; Guanine nucleotide exchange factor; Cell biology; Transfection; Biophysics; Biochemistry; Stereochemistry; GTPase; Biology; Recombinant DNA; Spodoptera","score_opus":0.018994703046232242,"score_gpt":0.29717807302989163,"score_spread":0.2781833699836594,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2994351462","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4808535,0.005052196,0.49451885,0.0009729474,0.00038575224,0.0008894621,0.001480557,0.0014185634,0.0144282775],"genre_scores_gemma":[0.7200385,0.0035796382,0.23244664,0.00039935557,0.00013588634,0.0024014707,0.0071038976,0.00022716455,0.03366748],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987877,0.00048651654,0.00006676164,0.00034414622,0.00017883116,0.00013598402],"domain_scores_gemma":[0.99925107,0.00038198094,0.00011213963,0.000088525936,0.00006607556,0.00010024254],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082690036,0.0010833225,0.0005362225,0.00078117364,0.0006445945,0.00058354065,0.000693502,0.0007994236,0.006679316],"category_scores_gemma":[0.00088278507,0.00050248567,0.0006261745,0.0006315828,0.0005290759,0.0006220058,0.00092184846,0.0031994234,0.0024086505],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011748262,0.0000819383,0.00006708106,0.00009923738,0.000014434431,0.000045592747,0.00005887813,0.000048050344,0.997359,0.0004995724,0.00011574596,0.0014930216],"study_design_scores_gemma":[0.0000270492,0.0003443904,0.001208716,0.000024738745,0.000035100875,0.00030063785,0.000044712255,0.0018538001,0.98975676,0.00022684032,0.0061626113,0.000014799381],"about_ca_topic_score_codex":0.0002470206,"about_ca_topic_score_gemma":0.0008121074,"teacher_disagreement_score":0.006679316,"about_ca_system_score_codex":0.0005973692,"about_ca_system_score_gemma":0.00035740566,"threshold_uncertainty_score":0.02234459},"labels":[],"label_agreement":null},{"id":"W2999829432","doi":"10.1126/scitranslmed.aba2906","title":"A potential gut punch to gastric cancer","year":2020,"lang":"en","type":"article","venue":"Science Translational Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cancer; Medicine; Cancer research; Drug resistance; Pharmacology; Drug; Biology; Internal medicine; Microbiology","score_opus":0.024653827631879018,"score_gpt":0.3094442472856073,"score_spread":0.2847904196537283,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2999829432","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.37206218,0.44724196,0.029280337,0.0416635,0.01397573,0.0006120629,0.0010076652,0.0029759877,0.09118063],"genre_scores_gemma":[0.70644027,0.18557669,0.02535962,0.02009222,0.0038978984,0.00045384857,0.00085878617,0.00017894465,0.057141736],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999232,0.000019273404,0.0000030386466,0.000016268526,0.000013510641,0.000024798263],"domain_scores_gemma":[0.9999006,0.000017176506,0.000017029855,0.000010024702,0.000012578639,0.000042556232],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023295722,0.0004877706,0.00053648296,0.00057798845,0.00045660874,0.0006886064,0.0004601541,0.0014612456,0.0144592095],"category_scores_gemma":[0.0002866556,0.0002096267,0.0006395747,0.00022322602,0.0004132141,0.0007514657,0.00062878075,0.0021294004,0.0029793086],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00441438,0.0011959508,0.0026984166,0.002483482,0.00021203545,0.009740343,0.00012342056,0.00066272996,0.21733315,0.0086995,0.043357816,0.7090788],"study_design_scores_gemma":[0.004148842,0.026433125,0.02174322,0.0018161449,0.0008329314,0.058086187,0.0009149959,0.002952822,0.13188376,0.012157189,0.7388783,0.00015250048],"about_ca_topic_score_codex":0.00021578395,"about_ca_topic_score_gemma":0.00081215956,"teacher_disagreement_score":0.0144592095,"about_ca_system_score_codex":0.00021343854,"about_ca_system_score_gemma":0.00023711473,"threshold_uncertainty_score":0.048370898},"labels":[],"label_agreement":null},{"id":"W3001962967","doi":"10.1139/bcb-2019-0082","title":"Ankyrin-B p.S646F undergoes increased proteasome degradation and reduces cell viability in the H9c2 rat ventricular cardiomyoblast cell line","year":2020,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of British Columbia; University of Victoria","funders":"Canadian Institutes of Health Research","keywords":"Viability assay; Proteasome; Cell culture; Chemistry; Cell; Cell biology; Biology; Internal medicine; Andrology; Biochemistry; Medicine; Genetics","score_opus":0.009956000648209855,"score_gpt":0.2165036756653029,"score_spread":0.20654767501709304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3001962967","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9970253,0.0006512997,0.00091985473,0.00007997513,0.00003019878,0.000007252685,0.0004888704,0.000049484897,0.0007476968],"genre_scores_gemma":[0.99340653,0.0005003927,0.0011423382,0.0000371034,0.000007973073,0.000030656127,0.00081419665,0.00002932742,0.004031442],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998337,0.000029471681,0.00002147311,0.000034811972,0.000052284882,0.000028193774],"domain_scores_gemma":[0.9999181,0.000014998089,0.000027772623,0.000011125561,0.000006210038,0.00002178433],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012355777,0.00035121906,0.000287523,0.0002484785,0.00018836807,0.00022486468,0.00017269848,0.000318845,0.0014689281],"category_scores_gemma":[0.000095129006,0.00013212561,0.00019364455,0.00018552163,0.00023378515,0.00012743323,0.00014689853,0.00044980718,0.000432609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000073116986,0.00001660604,0.0000964055,0.000012781152,0.000003601107,0.000085281776,0.0000065482695,0.000039389633,0.9993032,0.000028081753,0.000024861718,0.00031007858],"study_design_scores_gemma":[0.000017472323,0.00022794935,0.006056646,0.0000036971749,0.000010385947,0.00045838475,0.000029487597,0.0007997921,0.99113864,0.000037071048,0.0012149162,0.0000055105716],"about_ca_topic_score_codex":0.0011636938,"about_ca_topic_score_gemma":0.0014459086,"teacher_disagreement_score":0.0014689281,"about_ca_system_score_codex":0.00024407265,"about_ca_system_score_gemma":0.00014940911,"threshold_uncertainty_score":0.0049140453},"labels":[],"label_agreement":null},{"id":"W3002763297","doi":"10.1186/s12964-019-0473-9","title":"RNA sequencing reveals an additional Crz1-binding motif in promoters of its target genes in the human fungal pathogen Candida albicans","year":2020,"lang":"en","type":"article","venue":"Cell Communication and Signaling","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":113,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China; Canada Research Chairs","keywords":"Biology; Promoter; Chromatin immunoprecipitation; Candida albicans; Gene; Transcription factor; Electrophoretic mobility shift assay; RNA; DNA microarray; Microarray analysis techniques; Gene expression profiling; Gene expression; Mutant; Genetics; Molecular biology","score_opus":0.040164340476263626,"score_gpt":0.2673131283824185,"score_spread":0.22714878790615486,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3002763297","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9783941,0.00272545,0.008177271,0.00020085815,0.00008346584,0.000075339834,0.008176249,0.00030777857,0.0018593658],"genre_scores_gemma":[0.962037,0.0010793795,0.017172262,0.0003877195,0.000053076757,0.00016125597,0.016047906,0.00013034494,0.0029309688],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997657,0.000010524033,0.000009988234,0.00010571871,0.00006308774,0.000044996825],"domain_scores_gemma":[0.9997482,0.00006710454,0.000065258406,0.00002516478,0.000047729773,0.000046623314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010128232,0.00052566023,0.00029570778,0.00044464288,0.0003252677,0.00029854933,0.00023599513,0.0003149702,0.0016860797],"category_scores_gemma":[0.0002507599,0.00017691021,0.00045313538,0.00032568572,0.00019428057,0.000079384976,0.00014214517,0.0005077428,0.0009450386],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019594033,0.00001596356,0.00071461505,0.000072366965,0.0000074649074,0.00015098127,0.000025628693,0.000100964804,0.9963469,0.000058599184,0.00014533027,0.0021651958],"study_design_scores_gemma":[0.000037765225,0.00022201972,0.052132566,0.00005070785,0.00007947576,0.0011641036,0.00008305549,0.0016385914,0.93596154,0.00014063058,0.008464453,0.000025069885],"about_ca_topic_score_codex":0.0016134937,"about_ca_topic_score_gemma":0.0026255248,"teacher_disagreement_score":0.0016860797,"about_ca_system_score_codex":0.00043385767,"about_ca_system_score_gemma":0.00041463377,"threshold_uncertainty_score":0.005640447},"labels":[],"label_agreement":null},{"id":"W3006297435","doi":"10.3389/fmicb.2019.02879","title":"Epstein-Barr Virus Nuclear Antigen 1 Recruits Cyclophilin A to Facilitate the Replication of Viral DNA Genome","year":2019,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Key Research and Development Program of China; University of Toronto; University of Pennsylvania","keywords":"Cypa; Biology; Viral replication; Virology; Virus; Cyclophilin A; Host factor; Molecular biology","score_opus":0.01431775380217981,"score_gpt":0.22694298027410684,"score_spread":0.21262522647192703,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006297435","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.985797,0.0060532647,0.0044572256,0.00017254047,0.000048950005,0.000030274017,0.00032801626,0.000108931956,0.0030036948],"genre_scores_gemma":[0.9946508,0.0017087596,0.0010514134,0.00004393284,0.000012545623,0.000017410965,0.0002989368,0.0000060425714,0.0022101798],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999418,0.000011266327,0.0000031571067,0.00001599246,0.000013390443,0.000014493069],"domain_scores_gemma":[0.9999734,0.000004230946,0.000006624043,0.0000031884085,0.0000044418525,0.000008116892],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000055059656,0.0002152747,0.00013607526,0.00014687948,0.0001830113,0.00022735553,0.00007242701,0.00017559466,0.0011162768],"category_scores_gemma":[0.00006887621,0.00008068631,0.00022743638,0.00009178158,0.000120265315,0.00018607402,0.00022357769,0.00027214346,0.0002443847],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000054137465,0.000012989052,0.00071175897,0.000047546513,0.0000074314003,0.00010075288,0.000010497469,0.000043851305,0.99640936,0.00020939311,0.0000914981,0.002300637],"study_design_scores_gemma":[0.000017003124,0.00023245449,0.027188752,0.000012412922,0.00003942697,0.00078074564,0.00007482339,0.0029070603,0.9541808,0.00029128368,0.014266117,0.000009150708],"about_ca_topic_score_codex":0.00033783575,"about_ca_topic_score_gemma":0.0006273076,"teacher_disagreement_score":0.0011162768,"about_ca_system_score_codex":0.000234074,"about_ca_system_score_gemma":0.00016120696,"threshold_uncertainty_score":0.0037342906},"labels":[],"label_agreement":null},{"id":"W3006481764","doi":"10.1074/jbc.ra119.011136","title":"ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1)","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University Health Network; Ontario Institute for Cancer Research","funders":"National Institute of General Medical Sciences; Deutsche Forschungsgemeinschaft","keywords":"Rhomboid; Chemistry; Biochemistry; Enzyme; Proteases","score_opus":0.05197245163751866,"score_gpt":0.29263135646817495,"score_spread":0.2406589048306563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006481764","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99517375,0.0014127585,0.0022175654,0.000076960256,0.000034107394,0.000007860269,0.00027165838,0.00008031655,0.0007249462],"genre_scores_gemma":[0.99549556,0.0006311111,0.0014004383,0.00003716483,0.000011383836,0.000012700798,0.00064204604,0.000032533582,0.0017370682],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998274,0.000020928197,0.00001550462,0.000052399762,0.00004381418,0.00003987284],"domain_scores_gemma":[0.99985147,0.000017573919,0.00006646809,0.000023672663,0.000015086099,0.000025646976],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001591392,0.00026616937,0.00022406444,0.0001845453,0.00017252895,0.000344419,0.00020675379,0.00026229158,0.0014225839],"category_scores_gemma":[0.0001422539,0.00014575955,0.00029240974,0.00011123248,0.00017537881,0.00022271919,0.00025022207,0.0004327445,0.00067196076],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005752946,0.0000051384513,0.00031875717,0.000023364128,0.000007471085,0.00007331701,0.000011191846,0.00002192457,0.9989114,0.00005634797,0.000036496494,0.00047705678],"study_design_scores_gemma":[0.000009154464,0.00007487753,0.00629104,0.0000056950485,0.000017409739,0.0006466914,0.000035560053,0.00041934568,0.9890097,0.000038788792,0.0034472977,0.000004268425],"about_ca_topic_score_codex":0.0002215129,"about_ca_topic_score_gemma":0.00027777636,"teacher_disagreement_score":0.0014225839,"about_ca_system_score_codex":0.0001848949,"about_ca_system_score_gemma":0.000108696884,"threshold_uncertainty_score":0.0047590137},"labels":[],"label_agreement":null},{"id":"W3006788691","doi":"10.1016/j.cub.2020.01.041","title":"RCAN1 Regulates Bidirectional Synaptic Plasticity","year":2020,"lang":"en","type":"article","venue":"Current Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Canadian Institutes of Health Research; Alzheimer Society","keywords":"Biology; Synaptic plasticity; Plasticity; Neuroscience; Metaplasticity; Genetics","score_opus":0.03431760427856116,"score_gpt":0.2849738087141301,"score_spread":0.2506562044355689,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3006788691","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9371006,0.014663541,0.011338976,0.002356069,0.0007350557,0.00006998106,0.001188443,0.00049342244,0.032053895],"genre_scores_gemma":[0.9849829,0.002900125,0.0028877002,0.00024893304,0.000055941047,0.000031313237,0.0005367939,0.000069399015,0.0082868915],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999777,0.000029283565,0.000009971026,0.000051036193,0.00006388614,0.00006876655],"domain_scores_gemma":[0.9997781,0.00002050346,0.000057005353,0.000023109715,0.000040307285,0.00008106082],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003089139,0.000566796,0.00028705297,0.00048059673,0.000582697,0.0010871358,0.00083252555,0.0006504621,0.003093472],"category_scores_gemma":[0.00026469197,0.0001807399,0.00035434868,0.00022217326,0.0005345912,0.0006702949,0.0005630713,0.0012850564,0.0012616062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00037946188,0.000046733556,0.0005501632,0.00010088067,0.000022095694,0.00032790462,0.000029939269,0.00042991285,0.98486114,0.004912368,0.0012120752,0.007127332],"study_design_scores_gemma":[0.00004391477,0.00010898197,0.015429525,0.000054899592,0.000059101003,0.0008643449,0.00012849497,0.0076106144,0.95108926,0.0024998914,0.022074599,0.000036447236],"about_ca_topic_score_codex":0.0016187516,"about_ca_topic_score_gemma":0.0030035276,"teacher_disagreement_score":0.003093472,"about_ca_system_score_codex":0.0014845245,"about_ca_system_score_gemma":0.00060689537,"threshold_uncertainty_score":0.010771036},"labels":[],"label_agreement":null},{"id":"W3008414836","doi":"10.1038/s41591-020-0757-z","title":"TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma","year":2020,"lang":"en","type":"article","venue":"Nature Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":80,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Terry Fox Research Institute; Canada's Michael Smith Genome Sciences Centre; BC Cancer Agency; Simon Fraser University; Trillium Therapeutics (Canada); University of British Columbia; Spinal Cord Injury BC","funders":"Canadian Institutes of Health Research; National Institutes of Health; Terry Fox Research Institute","keywords":"Lymphoma; Vulnerability (computing); Function (biology); Cancer research; Loss function; Biology; Mutation; Genetics; Immunology; Gene; Computer science; Phenotype; Computer security","score_opus":0.014973207738149533,"score_gpt":0.269722264428422,"score_spread":0.2547490566902725,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3008414836","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99373996,0.0007077554,0.0015833054,0.00022574648,0.000041223615,0.00003615548,0.0005641991,0.00021042366,0.0028912404],"genre_scores_gemma":[0.9984493,0.00017229687,0.0003740792,0.00003660884,0.0000052164482,0.000014859683,0.00014952176,0.00002749372,0.00077050965],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980706,0.00004441586,0.00002143076,0.000028101085,0.000050575247,0.000048477974],"domain_scores_gemma":[0.99982494,0.000046258658,0.000049680766,0.000019692296,0.000006791148,0.000052689673],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017322539,0.0003362725,0.00025502927,0.0003779444,0.00023333222,0.00042705805,0.00028591647,0.00054903625,0.003544704],"category_scores_gemma":[0.00022309432,0.00020272912,0.00024233818,0.00024432782,0.00044468802,0.00023180773,0.00036678865,0.00091547944,0.0009763551],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001407254,0.00007191369,0.00031678952,0.000021954389,0.000010684725,0.00032174107,0.000017142162,0.00036092175,0.99592566,0.00063979084,0.00019598269,0.001976795],"study_design_scores_gemma":[0.00017476942,0.00077666447,0.012968225,0.00001674408,0.000048770566,0.0067466134,0.0001124324,0.0072704814,0.9598941,0.0011653134,0.010800455,0.000025440138],"about_ca_topic_score_codex":0.00040382805,"about_ca_topic_score_gemma":0.000684887,"teacher_disagreement_score":0.003544704,"about_ca_system_score_codex":0.00039459893,"about_ca_system_score_gemma":0.00018938522,"threshold_uncertainty_score":0.0118582845},"labels":[],"label_agreement":null},{"id":"W3011974553","doi":"10.1016/j.bbrc.2020.03.062","title":"FKBP12 dimerization mutations effect FK506 binding and differentially alter calcineurin inhibition in the human pathogen Aspergillus fumigatus","year":2020,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; National Institutes of Health","keywords":"FKBP; Calcineurin; Aspergillus fumigatus; In vivo; Mutant; Biology; Plasma protein binding; Dimer; Fungal protein; Chemistry; Cell biology; Biochemistry; Microbiology; Transplantation; Genetics; Gene; Medicine","score_opus":0.06134863285291346,"score_gpt":0.3599375714168602,"score_spread":0.29858893856394675,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3011974553","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99786913,0.00023814513,0.000524266,0.00008464363,0.000034215624,0.000008023499,0.0002679502,0.000055340024,0.00091824075],"genre_scores_gemma":[0.9985103,0.00007597539,0.0003610411,0.000049848593,0.0000035774085,0.0000059859376,0.0001454329,0.0000162746,0.0008316043],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996884,0.000070730894,0.000041716266,0.00005240227,0.00007259034,0.000074191965],"domain_scores_gemma":[0.9997973,0.000042805405,0.000048617138,0.000022091943,0.000016553806,0.00007263371],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001434061,0.00028822507,0.00023309272,0.00026357785,0.00031068482,0.00026321548,0.0002947713,0.0004567796,0.0034474274],"category_scores_gemma":[0.0002157434,0.00022018714,0.000207828,0.00019564877,0.00033472857,0.00013270933,0.00021162066,0.00049456174,0.0007411364],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018524412,0.000043180135,0.00015045986,0.0000110085775,0.000005837385,0.000058414083,0.000008584542,0.000114319286,0.9989058,0.00009007928,0.000056187637,0.00037089092],"study_design_scores_gemma":[0.000051138817,0.00024011212,0.009445685,0.0000078652665,0.000027813025,0.00046266627,0.000055241584,0.0016926897,0.9866239,0.00008655048,0.0012930548,0.000013357339],"about_ca_topic_score_codex":0.0034239404,"about_ca_topic_score_gemma":0.0051061637,"teacher_disagreement_score":0.0034474274,"about_ca_system_score_codex":0.00040707047,"about_ca_system_score_gemma":0.00025228053,"threshold_uncertainty_score":0.011532724},"labels":[],"label_agreement":null},{"id":"W3013691493","doi":"10.1074/jbc.ra119.011029","title":"Calreticulin regulates a switch between osteoblast and chondrocyte lineages derived from murine embryonic stem cells","year":2020,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Government of Canada","keywords":"Calreticulin; Cell biology; Endoplasmic reticulum; NFAT; Biology; Osteoblast; Chondrogenesis; Cellular differentiation; DKK1; Wnt signaling pathway; Stem cell; Signal transduction; Transcription factor; Biochemistry","score_opus":0.023351633158611353,"score_gpt":0.23174328640553246,"score_spread":0.2083916532469211,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3013691493","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9924533,0.0016833026,0.0020985173,0.00012495715,0.000047281657,0.00002995207,0.0007669884,0.00008712665,0.0027085508],"genre_scores_gemma":[0.9902208,0.00090813305,0.0024427457,0.00009478226,0.0000068916675,0.000037994472,0.00088919123,0.000045293593,0.0053541875],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998617,0.000017549715,0.000014845126,0.000032545624,0.00003858642,0.000034609926],"domain_scores_gemma":[0.9998933,0.000015018069,0.000035447578,0.000011446837,0.000010355133,0.000034450877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009860896,0.0002854616,0.00018369556,0.0002728946,0.00014036242,0.00027892995,0.0001349216,0.0002320753,0.0014754849],"category_scores_gemma":[0.000109747874,0.00015582953,0.0001795742,0.00015289687,0.00022857726,0.00012568351,0.00023312785,0.00042681347,0.0004432256],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000049349506,0.000007034628,0.00011941483,0.0000132513815,0.0000018104105,0.000023113067,0.000004235032,0.00001436084,0.9991596,0.00006495481,0.000017152486,0.0005257919],"study_design_scores_gemma":[0.000014419331,0.000054401433,0.0044084843,0.0000038937264,0.000007599497,0.000098906276,0.000011889728,0.0002519701,0.9931623,0.000025315694,0.0019587944,0.0000020408527],"about_ca_topic_score_codex":0.00080626033,"about_ca_topic_score_gemma":0.0028421772,"teacher_disagreement_score":0.0014754849,"about_ca_system_score_codex":0.00045233418,"about_ca_system_score_gemma":0.00028171265,"threshold_uncertainty_score":0.00493598},"labels":[],"label_agreement":null},{"id":"W3014446581","doi":"10.1523/jneurosci.1397-19.2020","title":"Basigin Associates with Integrin in Order to Regulate Perineurial Glia and<i>Drosophila</i>Nervous System Morphology","year":2020,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Child Health and Human Development; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Basigin; Nervous system; Drosophila (subgenus); Neuroscience; Cell biology; Biology; Integrin; Morphology (biology); Cell; Genetics; Gene","score_opus":0.014904561431177715,"score_gpt":0.23726455879109892,"score_spread":0.2223599973599212,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3014446581","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98577315,0.0016038907,0.008057105,0.0001419379,0.000031615764,0.000017468261,0.00023986434,0.00018109728,0.003953865],"genre_scores_gemma":[0.9908695,0.00068552076,0.0029693893,0.000095867596,0.000007622786,0.000020686664,0.00033328414,0.00006740253,0.004950736],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991834,0.000007742535,0.000005576276,0.000023875586,0.000024879155,0.000019516925],"domain_scores_gemma":[0.9999356,0.0000044674416,0.000029146106,0.000004513701,0.00000870047,0.000017426271],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006043905,0.00035148385,0.00012008607,0.00013223969,0.0002528734,0.00037947425,0.0002766217,0.00026947967,0.0007182929],"category_scores_gemma":[0.00006552247,0.00019453822,0.00017478383,0.00007837606,0.00021814741,0.00020294497,0.0003447822,0.0005066304,0.00038915544],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00001275157,0.0000023668115,0.00018567666,0.000014761316,0.0000015137341,0.00003209314,0.000009914278,0.00005471773,0.99914527,0.00010162314,0.000027991415,0.00041131926],"study_design_scores_gemma":[0.000011597811,0.000043620497,0.019596864,0.000011662028,0.000017880608,0.0002822241,0.000051600295,0.0027240866,0.9708591,0.000069107984,0.006325376,0.0000070243655],"about_ca_topic_score_codex":0.0018184441,"about_ca_topic_score_gemma":0.004296778,"teacher_disagreement_score":0.0018184441,"about_ca_system_score_codex":0.0007059416,"about_ca_system_score_gemma":0.00014983384,"threshold_uncertainty_score":0.005122006},"labels":[],"label_agreement":null},{"id":"W3015308921","doi":"10.1096/fasebj.21.5.a126-a","title":"Calcineurin, a serine/threonine phosphatase, is required for GPCR‐triggered association of paxillin, a cytoplasmic adapter protein, with high affinity α4β1 integrins in U937 cells","year":2007,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Paxillin; Calcineurin; Cell biology; Serine; Integrin; Phosphatase; Chemistry; Signal transducing adaptor protein; Phosphorylation; Biology; Biochemistry; Focal adhesion; Receptor; Transplantation; Internal medicine","score_opus":0.012127167550948413,"score_gpt":0.23722853287067944,"score_spread":0.22510136531973102,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3015308921","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9941759,0.0024420982,0.001565227,0.00012555734,0.000031762374,0.000034483845,0.00032932576,0.000067671695,0.0012279586],"genre_scores_gemma":[0.9940726,0.0011247029,0.0013354095,0.000051937135,0.000012726553,0.000054763714,0.00077241997,0.000014703036,0.0025608302],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997688,0.00003334763,0.000037673828,0.00004110295,0.00006245417,0.000056598652],"domain_scores_gemma":[0.9998797,0.000025418762,0.00003343314,0.000018388906,0.000015808988,0.000027254699],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000171228,0.0003616828,0.0003199955,0.00018740623,0.00029220575,0.0005104007,0.0002666718,0.00032670665,0.0010090753],"category_scores_gemma":[0.00015931774,0.00017468969,0.00034550362,0.00017633845,0.00018725172,0.00023381838,0.00018547264,0.00045186764,0.00037518312],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000076239965,0.000022626746,0.00011349618,0.000025567331,0.000003346238,0.000074012016,0.000012257869,0.000019106361,0.9991296,0.00005642697,0.000021226448,0.00044611635],"study_design_scores_gemma":[0.000018726316,0.0001195738,0.00999198,0.0000052055334,0.000017140483,0.00021859433,0.00003950179,0.00080900773,0.9871744,0.000027748512,0.0015738567,0.0000042823963],"about_ca_topic_score_codex":0.0016634436,"about_ca_topic_score_gemma":0.0021661557,"teacher_disagreement_score":0.0016634436,"about_ca_system_score_codex":0.00044909256,"about_ca_system_score_gemma":0.00026194195,"threshold_uncertainty_score":0.003375709},"labels":[],"label_agreement":null},{"id":"W3016945236","doi":"10.1101/2020.04.14.039800","title":"Leveraging Fungal Calcineurin-Inhibitor Structures, Biophysics and Dynamics to Design Selective and Non-Immunosuppressive FK506 Analogs","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Office of Science; National Institutes of Health; Argonne National Laboratory; Basic Energy Sciences; Amplyx; U.S. Department of Energy","keywords":"Calcineurin; FKBP; Antifungal drug; Biology; Antifungal; Microbiology; Biochemistry; Transplantation; Medicine","score_opus":0.011611405327167475,"score_gpt":0.2185044539849325,"score_spread":0.20689304865776503,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3016945236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96147513,0.002297658,0.031766627,0.00033575515,0.00004085614,0.000049234506,0.0002476466,0.00024764848,0.003539431],"genre_scores_gemma":[0.9798623,0.0012572395,0.018019257,0.000058107304,0.0000058074925,0.000033888777,0.00028835228,0.0000371579,0.00043785485],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999527,0.0000056648405,0.000003641715,0.000012065001,0.000016608374,0.000009292265],"domain_scores_gemma":[0.99993384,0.000016841757,0.000017821163,0.000007385599,0.000012202939,0.00001188855],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013295557,0.00035225152,0.00027807124,0.000093918854,0.00019831501,0.00037061548,0.00030666907,0.00021167556,0.0007568056],"category_scores_gemma":[0.00022559954,0.0001400449,0.00018193258,0.00010733083,0.0001887242,0.00034996017,0.0001972847,0.00059355487,0.0001782164],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000303138,0.00026486526,0.0033588046,0.00032324312,0.00009005448,0.00025981525,0.00009780255,0.19539092,0.7733301,0.006974957,0.0009308247,0.018675474],"study_design_scores_gemma":[0.00014080995,0.000581669,0.002347822,0.000038628204,0.00007971415,0.00021189373,0.00009213043,0.5767389,0.4079856,0.0023262333,0.009399496,0.000057180758],"about_ca_topic_score_codex":0.002375695,"about_ca_topic_score_gemma":0.0031495013,"teacher_disagreement_score":0.002375695,"about_ca_system_score_codex":0.0005573571,"about_ca_system_score_gemma":0.00037029656,"threshold_uncertainty_score":0.0047237873},"labels":[],"label_agreement":null},{"id":"W3017116690","doi":"10.1096/fasebj.2020.34.s1.04927","title":"Induction And Regulation of Endogenous DARC Expression in Primary Human Endothelial Cells","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemokine; Cell biology; Biology; Endothelium; Endothelial stem cell; Receptor; Chemokine receptor; Immunology; Endogeny; In vivo; Molecular biology; In vitro; Inflammation; Genetics; Biochemistry","score_opus":0.028716530128479346,"score_gpt":0.2334931267850818,"score_spread":0.20477659665660244,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017116690","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9505691,0.009551179,0.025066039,0.00036108855,0.0003069387,0.0002802633,0.005415905,0.00042615924,0.008023302],"genre_scores_gemma":[0.9598727,0.0040702834,0.01948368,0.00030675903,0.000094753224,0.00041502772,0.0071992124,0.000054982236,0.008502516],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99945456,0.00009399146,0.0000667265,0.00012919599,0.00013480178,0.000120775614],"domain_scores_gemma":[0.9997904,0.00004680866,0.000020069203,0.000057594476,0.00005641939,0.000028843646],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034906936,0.00018922368,0.00038310292,0.00028016235,0.0002362036,0.0004715727,0.00020587408,0.0002588528,0.0016943468],"category_scores_gemma":[0.00022100046,0.00016415132,0.00042670462,0.00039079608,0.00019219892,0.0001430667,0.00021688583,0.0006582277,0.00086397043],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000094913215,0.0000587823,0.0001554665,0.000052356754,0.000005867742,0.00007557088,0.000044802546,0.00005345191,0.99783653,0.00018289662,0.00017216649,0.001267297],"study_design_scores_gemma":[0.000027662045,0.00037785745,0.0065191262,0.00001133874,0.000022139579,0.00031073307,0.000049259914,0.0011377855,0.9823674,0.000057431942,0.009111382,0.000007954529],"about_ca_topic_score_codex":0.0009778766,"about_ca_topic_score_gemma":0.0012387477,"teacher_disagreement_score":0.0016943468,"about_ca_system_score_codex":0.0003833612,"about_ca_system_score_gemma":0.00026066243,"threshold_uncertainty_score":0.0056681633},"labels":[],"label_agreement":null},{"id":"W3017249132","doi":"10.1096/fasebj.2020.34.s1.07593","title":"Uncovering The Unique Functions And Regulation Of The Palmitoylated Calcineurin Isoform, CNβ1","year":2020,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia; Lunenfeld-Tanenbaum Research Institute","funders":"","keywords":"Palmitoylation; NFAT; Gene isoform; Phosphatase; Cell biology; Protein subunit; Biochemistry; Isozyme; Chemistry; Calcineurin; Phosphorylation; Flippase; Cysteine; Biology; Enzyme; Transcription factor; Gene; Membrane","score_opus":0.014281379735100104,"score_gpt":0.22182758613526377,"score_spread":0.20754620640016366,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3017249132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9929345,0.003698227,0.002231446,0.00014378795,0.000025787162,0.00001174111,0.00021738287,0.000021054355,0.0007159672],"genre_scores_gemma":[0.9916611,0.0034479795,0.0019972785,0.00011029856,0.000024972669,0.000016629612,0.00051375275,0.000015970836,0.0022120331],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999347,0.0000044271455,0.000004099414,0.000024286268,0.000017406457,0.000015169865],"domain_scores_gemma":[0.9999485,0.0000045550823,0.000017631932,0.0000046705177,0.00001057984,0.0000140193],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011213739,0.0002773397,0.00015375932,0.00016448741,0.000149909,0.00023931099,0.00018559399,0.0001914837,0.00038873145],"category_scores_gemma":[0.00008680662,0.00012377439,0.0001489245,0.00010591032,0.00023371362,0.00024471857,0.00017583359,0.0003984257,0.00013209789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045928024,0.000005260366,0.0003542175,0.00002217125,0.000001961803,0.000042474614,0.000013638822,0.000022636541,0.99875605,0.00009127156,0.000014520874,0.00062982034],"study_design_scores_gemma":[0.000024930068,0.0001401031,0.057582043,0.000013551064,0.000031996435,0.0010820709,0.00009025048,0.0028750952,0.93203133,0.00030036448,0.005817342,0.000010951883],"about_ca_topic_score_codex":0.00081511505,"about_ca_topic_score_gemma":0.0013442168,"teacher_disagreement_score":0.00081511505,"about_ca_system_score_codex":0.0003338948,"about_ca_system_score_gemma":0.00021644807,"threshold_uncertainty_score":0.0024225712},"labels":[],"label_agreement":null},{"id":"W3020335007","doi":"10.4049/immunohorizons.2000016","title":"Cyclophilin D Regulates Antiviral CD8+ T Cell Survival in a Cell-Extrinsic Manner","year":2020,"lang":"en","type":"article","venue":"ImmunoHorizons","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research; McGill University Health Centre; Fonds de Recherche du Québec - Santé; Fondation Jean-Louis Lévesque; McGill University","keywords":"Cyclophilin A; Cell biology; Biology; Cell; Cytotoxic T cell; Cyclophilin; CD8; T cell; Cell survival; Virology; Immunology; Molecular biology; Genetics; Apoptosis; Immune system; Gene","score_opus":0.011967859975113654,"score_gpt":0.2287799337991095,"score_spread":0.21681207382399584,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3020335007","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99447554,0.0013902617,0.0016521777,0.00014677516,0.000020890073,0.000010482133,0.00028425417,0.000033548804,0.001986065],"genre_scores_gemma":[0.997948,0.00037164442,0.00033828092,0.000031780397,0.0000064685364,0.000009394169,0.00012309455,0.0000034529469,0.0011680508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999329,0.000014723205,0.000003813302,0.0000135004175,0.000011613185,0.000023483475],"domain_scores_gemma":[0.99994576,0.000007718706,0.000016569657,0.000006055212,0.000006498804,0.000017332919],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005164438,0.00016316104,0.00008502117,0.00012334294,0.00013609564,0.00021474682,0.00010323326,0.00017746098,0.0015206336],"category_scores_gemma":[0.00005548713,0.00006234873,0.00010727262,0.00006105413,0.00019740907,0.00011417082,0.00015235171,0.00027841772,0.00024045596],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001288038,0.000011612105,0.0003839386,0.000020076359,0.0000024012575,0.000039875766,0.0000048682564,0.000030138874,0.99848676,0.00011285583,0.000052285952,0.00072632334],"study_design_scores_gemma":[0.000021151418,0.00013957515,0.019202938,0.0000085904785,0.000012464468,0.00016789942,0.000040194725,0.0010267657,0.97677535,0.0000997861,0.0025023154,0.0000029688836],"about_ca_topic_score_codex":0.00020058296,"about_ca_topic_score_gemma":0.00046761546,"teacher_disagreement_score":0.0015206336,"about_ca_system_score_codex":0.00025991644,"about_ca_system_score_gemma":0.00010919847,"threshold_uncertainty_score":0.005087018},"labels":[],"label_agreement":null},{"id":"W3035130407","doi":"10.7554/elife.52237","title":"Hepatitis C virus exploits cyclophilin A to evade PKR","year":2020,"lang":"en","type":"article","venue":"eLife","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Faculty of Health Sciences, Queen's University; Deutsche Forschungsgemeinschaft; Queen's University; European Commission; Engineering and Physical Sciences Research Council; Canadian Institutes of Health Research; National Institute for Health and Care Research; University College London; Wellcome Trust; Medical Research Council; Wellcome","keywords":"Cypa; Cyclophilin A; Protein kinase R; Hepatitis C virus; Interferon; Innate immune system; Effector; Antiviral protein; Viral replication; Virus","score_opus":0.02260253021849354,"score_gpt":0.2571391309500581,"score_spread":0.23453660073156454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3035130407","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9843156,0.0032795828,0.005025876,0.00052022503,0.00006421263,0.000019808114,0.00017331609,0.00013652058,0.0064649335],"genre_scores_gemma":[0.9964641,0.00079190684,0.0010298147,0.00007348403,0.00001310716,0.00000613214,0.000085954474,0.0000055110495,0.0015300584],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999409,0.0000129017535,0.000003487983,0.000010878518,0.000014695645,0.000017208204],"domain_scores_gemma":[0.99997556,0.000003018541,0.0000075475436,0.0000035310954,0.0000023178504,0.000008167989],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009259005,0.00020157994,0.00008892341,0.00012845486,0.00015468414,0.0002485716,0.00009625364,0.00017278611,0.0007346316],"category_scores_gemma":[0.00004891993,0.00006462153,0.00012483988,0.000066207154,0.00017850006,0.0001271469,0.00020079211,0.00028131326,0.0002460463],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051933446,0.00001155078,0.00031865563,0.000016104932,0.000004444033,0.000053117274,0.0000037821733,0.00008245013,0.9968252,0.00042275805,0.000094238814,0.0021158636],"study_design_scores_gemma":[0.000019658144,0.00028007178,0.0080280155,0.0000082968045,0.0000125625065,0.00067307317,0.000030085635,0.0026732818,0.98078936,0.00033990515,0.007138953,0.000006792118],"about_ca_topic_score_codex":0.00035874514,"about_ca_topic_score_gemma":0.0006784639,"teacher_disagreement_score":0.0007346316,"about_ca_system_score_codex":0.00025720082,"about_ca_system_score_gemma":0.00017390029,"threshold_uncertainty_score":0.002457559},"labels":[],"label_agreement":null},{"id":"W3042076923","doi":"10.1016/j.molcel.2020.06.029","title":"Systematic Discovery of Short Linear Motifs Decodes Calcineurin Phosphatase Signaling","year":2020,"lang":"en","type":"article","venue":"Molecular Cell","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lunenfeld-Tanenbaum Research Institute; University of Toronto; Mount Sinai Hospital","funders":"National Institute of General Medical Sciences; Carl Tryggers Stiftelse för Vetenskaplig Forskning; Ontario Genomics; National Institutes of Health; Vetenskapsrådet; Science Foundation Ireland; Government of Canada; Canadian Institutes of Health Research; LOEWE-Zentrum für Translationale Medizin und Pharmakologie; Ontario Research Foundation; Government of Ontario; Stanford University","keywords":"Biology; In silico; Phosphatase; Calcineurin; Cell biology; Interactome; Proteome; Computational biology; Nuclear transport; Ankyrin repeat; Biochemistry; Phosphorylation; Gene; Cell nucleus","score_opus":0.012575438289918181,"score_gpt":0.23655069185634478,"score_spread":0.2239752535664266,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042076923","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9371401,0.0015556698,0.054505166,0.00065278786,0.00022716614,0.00016852359,0.0010679498,0.00088798616,0.0037946752],"genre_scores_gemma":[0.9612575,0.0010516031,0.032566797,0.00025814428,0.000036387635,0.000060956947,0.0013628388,0.00022947765,0.003176239],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979955,0.000040307037,0.000015280599,0.000039654064,0.000066038025,0.000039229548],"domain_scores_gemma":[0.9996093,0.00013425271,0.000090781214,0.000045914334,0.00005532002,0.00006448399],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003971058,0.00045048795,0.00042046158,0.00027972678,0.0002567997,0.00071377394,0.00050145644,0.0005333422,0.0014756127],"category_scores_gemma":[0.0008505438,0.00029852457,0.0003468349,0.00029006347,0.0003699545,0.00027075317,0.00048837403,0.0015616876,0.00072699273],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025903137,0.000045004268,0.00047012916,0.00005701891,0.000018343466,0.00018271945,0.000024440411,0.0010572168,0.9899379,0.001859919,0.00016593742,0.0059224227],"study_design_scores_gemma":[0.0000451396,0.00040670804,0.0009829128,0.0000147769615,0.000051894705,0.00027656634,0.00003832008,0.010606676,0.9805387,0.0010287954,0.0059865913,0.000022847818],"about_ca_topic_score_codex":0.000689088,"about_ca_topic_score_gemma":0.0018509121,"teacher_disagreement_score":0.0014756127,"about_ca_system_score_codex":0.00060018216,"about_ca_system_score_gemma":0.0005705008,"threshold_uncertainty_score":0.004936397},"labels":[],"label_agreement":null},{"id":"W3042791234","doi":"10.3389/fphys.2020.00735","title":"An Overview of the Role of Calcium/Calmodulin-Dependent Protein Kinase in Cardiorenal Syndrome","year":2020,"lang":"en","type":"review","venue":"Frontiers in Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Cardiorenal syndrome; Calmodulin; Calcium; Cell biology; Protein kinase A; Kinase; Calcium-binding protein; Biology; Medicine; Internal medicine; Endocrinology; Heart failure","score_opus":0.02750895006179854,"score_gpt":0.29975429343218135,"score_spread":0.2722453433703828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3042791234","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00010385731,0.9990177,0.00007872068,0.00019083728,0.00012570464,0.0000035089301,0.000026859283,0.000005313395,0.0004474761],"genre_scores_gemma":[0.0004988314,0.99893576,0.00013695027,0.00011660799,0.00010521381,0.0000046752525,0.000037327638,8.2742105e-7,0.00016383798],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998331,0.000029147452,0.00004750123,0.000029581059,0.000044280914,0.000016288965],"domain_scores_gemma":[0.99962616,0.00021664133,0.000048359503,0.0000068849913,0.00007569891,0.000026210962],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005085492,0.0006568412,0.0010627345,0.0035466957,0.00026858243,0.0007208047,0.0006028202,0.0008269583,0.0038448754],"category_scores_gemma":[0.0008651538,0.00023821056,0.00075644546,0.0028877202,0.00025194758,0.0010531001,0.0005445191,0.0011576694,0.00113151],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014609031,0.000065060995,0.00042586148,0.0723028,0.00024912992,0.00037315255,0.00012315222,0.00028056256,0.0021138403,0.0025216532,0.031529684,0.889869],"study_design_scores_gemma":[0.00003649197,0.00018972025,0.003206796,0.020565275,0.0008145892,0.0031957824,0.00010947888,0.00015288025,0.0006903203,0.0021965515,0.9688024,0.000039655082],"about_ca_topic_score_codex":0.0011082898,"about_ca_topic_score_gemma":0.0018688171,"teacher_disagreement_score":0.0038448754,"about_ca_system_score_codex":0.00049566914,"about_ca_system_score_gemma":0.0012493802,"threshold_uncertainty_score":0.012862444},"labels":[],"label_agreement":null},{"id":"W3044633513","doi":"10.1101/2020.07.24.219790","title":"Expression, subcellular localization, and phosphorylation of MK5 in adult cardiac ventricular fibroblasts","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute; Bell (Canada)","funders":"Heart and Stroke Foundation of Canada","keywords":"Myofibroblast; Kinase; Myocyte; p38 mitogen-activated protein kinases; Phosphorylation; Fibroblast; Cytoplasm; Cell biology; Endocrinology; Internal medicine; Chemistry; Biology; Protein kinase A; Medicine; Fibrosis; Biochemistry","score_opus":0.007156987433217899,"score_gpt":0.20044727282610483,"score_spread":0.19329028539288692,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3044633513","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9936913,0.0020733324,0.0026102515,0.000046141085,0.000018334482,0.000013334906,0.0004947988,0.000025292393,0.0010272298],"genre_scores_gemma":[0.99263906,0.0010728692,0.0023661675,0.000052655643,0.000013537152,0.000035726716,0.0008612796,0.000010524743,0.002948184],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998951,0.000011754678,0.000014447446,0.000026259879,0.00002785514,0.000024578932],"domain_scores_gemma":[0.9999213,0.000011626892,0.000023468652,0.00000789008,0.0000114990535,0.000024173918],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001216031,0.0002273074,0.000121738485,0.00016342606,0.00014130083,0.00020653727,0.00012291719,0.00018284036,0.00083390943],"category_scores_gemma":[0.000078499026,0.00013209159,0.00018990002,0.000100473895,0.000121641715,0.00013710627,0.00015850256,0.0002879147,0.00032986832],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100254896,0.000012459841,0.00042727494,0.00003353337,0.000003506037,0.000067758716,0.000024134139,0.000017936802,0.9987482,0.00004660467,0.000017783965,0.0005006283],"study_design_scores_gemma":[0.000028262308,0.0005957512,0.045799695,0.00001611324,0.00004679341,0.0007675305,0.00015652028,0.0010747182,0.94875544,0.000095267926,0.0026555173,0.000008367304],"about_ca_topic_score_codex":0.00063618994,"about_ca_topic_score_gemma":0.0006557988,"teacher_disagreement_score":0.00083390943,"about_ca_system_score_codex":0.0002160454,"about_ca_system_score_gemma":0.00011695145,"threshold_uncertainty_score":0.0027896762},"labels":[],"label_agreement":null},{"id":"W3045337298","doi":"10.1161/hypertensionaha.120.15558","title":"Ca <sup>2+</sup> -Dependent NOX5 (NADPH Oxidase 5) Exaggerates Cardiac Hypertrophy Through Reactive Oxygen Species Production","year":2020,"lang":"en","type":"article","venue":"Hypertension","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"British Heart Foundation; Ottawa Hospital Research Institute; University of Ottawa","keywords":"Internal medicine; NADPH oxidase; Endocrinology; Pressure overload; Angiotensin II; Oxidative stress; Muscle hypertrophy; Reactive oxygen species; Heart failure; Biology; Medicine; Blood pressure; Cell biology","score_opus":0.030608995036453996,"score_gpt":0.22314014489755155,"score_spread":0.19253114986109754,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3045337298","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98772484,0.0025072268,0.0059525566,0.0004487337,0.00014332683,0.000058392972,0.0004452682,0.00022564223,0.0024939985],"genre_scores_gemma":[0.9917395,0.0010446917,0.002615463,0.00020884091,0.00004831319,0.00006810348,0.00051628833,0.000035260495,0.0037234854],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997907,0.000027936827,0.000024757172,0.000034206074,0.000054974298,0.00006744655],"domain_scores_gemma":[0.999859,0.000010395264,0.000054469318,0.000013034767,0.000014108265,0.000049044902],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022953494,0.00049356924,0.00030529712,0.000233237,0.00014836296,0.0003060347,0.000255942,0.0003183223,0.0018109427],"category_scores_gemma":[0.000086955086,0.00022278863,0.00034995083,0.00013035983,0.00036228582,0.0002633503,0.00025053645,0.00062580185,0.00036605156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023975414,0.000024575533,0.0002118298,0.000046118737,0.0000066504813,0.00012160441,0.000008341,0.000023922868,0.99852186,0.00012260037,0.000058766433,0.0006140928],"study_design_scores_gemma":[0.00006364885,0.0005460065,0.011247275,0.000013595465,0.00004741873,0.00056026026,0.00004453732,0.0009894917,0.9834156,0.000141842,0.0029246754,0.000005618119],"about_ca_topic_score_codex":0.0003695023,"about_ca_topic_score_gemma":0.0005190797,"teacher_disagreement_score":0.0018109427,"about_ca_system_score_codex":0.00025296817,"about_ca_system_score_gemma":0.000153303,"threshold_uncertainty_score":0.006058216},"labels":[],"label_agreement":null},{"id":"W3047640951","doi":"10.14740/cr1120","title":"Cyclophilins in Ischemic Heart Disease: Differences Between Acute and Chronic Coronary Artery Disease Patients","year":2020,"lang":"en","type":"article","venue":"Cardiology Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Fundación Instituto de Investigación Sanitaria de Santiago de Compostela; Instituto de Salud Carlos III; Horizon 2020 Framework Programme; Interreg; European Commission; Xunta de Galicia","keywords":"Medicine; Coronary artery disease; Cypa; Internal medicine; Cardiology; Dyslipidemia; Biomarker; Gastroenterology; Disease; Immunology","score_opus":0.04836307268690748,"score_gpt":0.325434548275111,"score_spread":0.2770714755882035,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3047640951","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9990108,0.0004573756,0.000048299276,0.000021751242,0.000004531176,0.000005990851,0.00011584969,0.0000013656535,0.0003341016],"genre_scores_gemma":[0.9995074,0.00013294336,0.000061194165,0.000014785761,0.000015913156,0.0000063273233,0.00016997651,6.66764e-7,0.000090677306],"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999673,0.000082836756,0.00004510655,0.000073459385,0.0000673528,0.000058157784],"domain_scores_gemma":[0.99920076,0.00015104395,0.0003635928,0.00003443982,0.000066736466,0.00018358142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037475541,0.00021064974,0.00026483712,0.00066426874,0.0002997775,0.0005104401,0.00013491068,0.0004192003,0.0020559495],"category_scores_gemma":[0.0010701189,0.00013761985,0.00027042013,0.00062809256,0.00021193225,0.00023703086,0.00026029014,0.00040444793,0.0002308441],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019959795,0.00003326915,0.99865025,0.000008788962,0.000028148184,0.00005039595,0.000027298605,0.000007840853,0.00031912976,0.000008277256,0.000026117863,0.0006409721],"study_design_scores_gemma":[0.000006945406,0.000102188416,0.99942696,0.000002806163,0.000018639077,0.0002490349,0.000042073727,0.000029210009,0.000043480508,0.0000097741295,0.00006779358,0.0000011345235],"about_ca_topic_score_codex":0.00061184075,"about_ca_topic_score_gemma":0.0007728302,"teacher_disagreement_score":0.0020559495,"about_ca_system_score_codex":0.00013592483,"about_ca_system_score_gemma":0.00012636476,"threshold_uncertainty_score":0.0068778396},"labels":[],"label_agreement":null},{"id":"W3082665960","doi":"10.1016/j.scr.2020.101972","title":"Calreticulin regulates Src kinase in osteogenic differentiation from embryonic stem cells","year":2020,"lang":"en","type":"article","venue":"Stem Cell Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Calreticulin; Cell biology; Biology; Stem cell; Embryonic stem cell; Embryoid body; Proto-oncogene tyrosine-protein kinase Src; Tyrosine kinase; Cellular differentiation; Kinase; Endoplasmic reticulum; Molecular biology; Signal transduction; Adult stem cell; Biochemistry","score_opus":0.04625228604606329,"score_gpt":0.2909544372523644,"score_spread":0.24470215120630112,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082665960","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98283964,0.0057983194,0.0067065298,0.00022892533,0.00007489623,0.000062237705,0.0008320538,0.00013183075,0.0033256435],"genre_scores_gemma":[0.9847178,0.0027677268,0.0039314246,0.00013167858,0.00002200788,0.00006696702,0.0015981845,0.000050232426,0.0067139934],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978465,0.000019215055,0.000025893032,0.00005214623,0.00008715336,0.000031055635],"domain_scores_gemma":[0.9999231,0.000009065115,0.000021995325,0.000010785766,0.000016412703,0.000018554098],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017469602,0.00032003302,0.00033294276,0.00023013625,0.00019485474,0.00036907417,0.000208108,0.00023529728,0.0008068056],"category_scores_gemma":[0.00011011267,0.00019108463,0.00031767593,0.0002319835,0.00022317875,0.00022892994,0.00039808365,0.0006399165,0.00047405987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000345135,0.000007604456,0.000103153805,0.000026266782,0.0000015643925,0.00003213759,0.000008876582,0.000023653645,0.9989968,0.00007685892,0.000018550527,0.0006700786],"study_design_scores_gemma":[0.000018319015,0.000056407756,0.008373214,0.0000075193193,0.000013250414,0.0002080693,0.000025867452,0.0010538888,0.9863495,0.00009278893,0.0037955327,0.0000055289697],"about_ca_topic_score_codex":0.00075361814,"about_ca_topic_score_gemma":0.0014306736,"teacher_disagreement_score":0.0008068056,"about_ca_system_score_codex":0.00038490858,"about_ca_system_score_gemma":0.0002796369,"threshold_uncertainty_score":0.002792716},"labels":[],"label_agreement":null},{"id":"W3082736234","doi":"10.1016/j.bone.2020.115624","title":"Nfil3, a target of the NACA transcriptional coregulator, affects osteoblast and osteocyte gene expression differentially","year":2020,"lang":"en","type":"article","venue":"Bone","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Shriners Hospitals for Children - Canada; McGill University","funders":"Shriners Hospitals for Children","keywords":"RUNX2; Osteoblast; Cell biology; CREB; Gene knockdown; Transcription factor; Chemistry; Osteocyte; Osteocalcin; Molecular biology; Biology; Gene; Biochemistry; Alkaline phosphatase; In vitro","score_opus":0.009775313226749061,"score_gpt":0.19752351256335365,"score_spread":0.18774819933660458,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082736234","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.986725,0.003459603,0.005045949,0.00017357207,0.00006755575,0.000040654562,0.0024203158,0.00028819428,0.0017792401],"genre_scores_gemma":[0.9921191,0.0007349821,0.0027425666,0.00015403518,0.000008559873,0.000068073045,0.0015502465,0.00005252076,0.0025699136],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9997558,0.00001383991,0.000016077298,0.00006958324,0.00008210968,0.000062554514],"domain_scores_gemma":[0.99990344,0.000013357432,0.00003307106,0.0000067698106,0.000015162609,0.000028285936],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000111733076,0.00032183304,0.00034788233,0.00024335417,0.00019764957,0.00023981076,0.00017123976,0.00031235276,0.001345895],"category_scores_gemma":[0.00011951844,0.00015321473,0.00040373454,0.00016381906,0.00032992335,0.0001614317,0.00020246275,0.0005388529,0.00025139883],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000084118255,0.000008052,0.00023128076,0.000031495438,0.0000038370977,0.000016714328,0.000010033586,0.000022478229,0.9988663,0.000022505961,0.000026593521,0.0006766299],"study_design_scores_gemma":[0.00002476487,0.0001606712,0.017603891,0.000009572378,0.000035108664,0.00021325241,0.00006173597,0.0008639664,0.9782954,0.00006113613,0.0026623032,0.0000082884935],"about_ca_topic_score_codex":0.0016772896,"about_ca_topic_score_gemma":0.003940214,"teacher_disagreement_score":0.0016772896,"about_ca_system_score_codex":0.00041227273,"about_ca_system_score_gemma":0.00032257117,"threshold_uncertainty_score":0.0045024753},"labels":[],"label_agreement":null},{"id":"W3111852362","doi":"10.7554/elife.58952.sa1","title":"Decision letter: TrpML-mediated astrocyte microdomain Ca2+ transients regulate astrocyte–tracheal interactions","year":2020,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Astrocyte; Lipid microdomain; Neuroscience; Cell biology; Chemistry; Biology; Biochemistry; Central nervous system","score_opus":0.020298260004740176,"score_gpt":0.2944554458686013,"score_spread":0.2741571858638611,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3111852362","genre_codex":"commentary","genre_gemma":"editorial","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"editorial","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009745533,0.0011495348,0.00084904983,0.5164944,0.45289558,0.00030687987,0.0009493535,0.0005205876,0.025860095],"genre_scores_gemma":[0.016070163,0.0027944609,0.0025313355,0.3818791,0.31418183,0.000583327,0.0012831922,0.0005092104,0.2801674],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9912327,0.001323919,0.0007902361,0.0006532197,0.0046159127,0.0013839157],"domain_scores_gemma":[0.9529515,0.013656472,0.0017015855,0.0018707922,0.021982826,0.007836741],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008627796,0.00080506847,0.0019404487,0.0016299264,0.00414182,0.0067939395,0.0028025203,0.029186262,0.07185399],"category_scores_gemma":[0.07040964,0.000815767,0.0017077009,0.0007828454,0.0021533116,0.0027899393,0.0022348845,0.013993563,0.054448172],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000059466256,0.000017030123,0.0000785147,0.000043024596,0.000006375069,0.00029128438,0.000014255156,0.0000192043,0.000101287376,0.0006056659,0.99422616,0.004537846],"study_design_scores_gemma":[0.00013528821,0.00004018311,0.000778746,0.00017520222,0.000017558468,0.00037803318,0.00007408418,0.00045016233,0.0004023835,0.002800904,0.99471056,0.000036919133],"about_ca_topic_score_codex":0.003482663,"about_ca_topic_score_gemma":0.008463235,"teacher_disagreement_score":0.07185399,"about_ca_system_score_codex":0.0039894315,"about_ca_system_score_gemma":0.0069170883,"threshold_uncertainty_score":0.24037558},"labels":[],"label_agreement":null},{"id":"W3112513189","doi":"10.3390/ijms21249620","title":"Inhibition of BRD4 Reduces Neutrophil Activation and Adhesion to the Vascular Endothelium Following Ischemia Reperfusion Injury","year":2020,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Mount Sinai Hospital; University Health Network; Princess Margaret Cancer Centre; Hospital for Sick Children; University of Toronto","funders":"Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Kidney; Pharmacology; Acute kidney injury; Inflammation; In vivo; Endothelium; Cell adhesion molecule; Medicine; Reperfusion injury; Renal ischemia; Immunology; Ischemia; Internal medicine; Chemistry; Biology","score_opus":0.013857512387942429,"score_gpt":0.2729536501723746,"score_spread":0.2590961377844322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3112513189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825408,0.010091211,0.0032053061,0.0003128833,0.00012380398,0.00006139944,0.0011891293,0.00025128652,0.0022243029],"genre_scores_gemma":[0.9895964,0.0035824517,0.0020531698,0.00016167392,0.000016072285,0.00006489051,0.0016513693,0.000026355743,0.0028475365],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998503,0.000028170803,0.000012570379,0.000021923819,0.000036243055,0.000050826453],"domain_scores_gemma":[0.99993825,0.000008442624,0.00001726752,0.0000056268377,0.000010702655,0.000019712796],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018159272,0.0003296992,0.00055516633,0.00026634047,0.000118728974,0.00025387062,0.00033849504,0.00024772625,0.0021230287],"category_scores_gemma":[0.0001560801,0.00011634823,0.00041092298,0.00016717559,0.00014458859,0.00014833226,0.00015787718,0.0006312723,0.00038884688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0018159645,0.00035623246,0.0005516179,0.0003180461,0.000059461097,0.000056984038,0.000009309008,0.00065816805,0.98927957,0.000104504965,0.00041444553,0.0063757803],"study_design_scores_gemma":[0.00024968345,0.0031803853,0.006866302,0.000023248333,0.00010978934,0.00019489217,0.000024664618,0.002957043,0.97986186,0.000076289216,0.006443005,0.000012771015],"about_ca_topic_score_codex":0.0008020939,"about_ca_topic_score_gemma":0.0009993627,"teacher_disagreement_score":0.0021230287,"about_ca_system_score_codex":0.0002992589,"about_ca_system_score_gemma":0.0002844512,"threshold_uncertainty_score":0.007102251},"labels":[],"label_agreement":null},{"id":"W3114195050","doi":"10.1152/ajpheart.00515.2019","title":"GPR43 regulates sodium butyrate-induced angiogenesis and matrix remodeling","year":2020,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Instituto Nacional de Ciência e Tecnologia de Nanobiofarmacêutica; Fundação de Amparo à Pesquisa do Estado de Minas Gerais; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Angiogenesis; Sodium butyrate; Chemistry; Matrix (chemical analysis); Cell biology; Biology; Cancer research; Biochemistry","score_opus":0.01518947101861744,"score_gpt":0.25004713411424834,"score_spread":0.2348576630956309,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3114195050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9902351,0.0023883947,0.0045376834,0.0005259948,0.00007776506,0.000039198756,0.0003825103,0.00008953128,0.0017238591],"genre_scores_gemma":[0.9945755,0.0012368875,0.0019483389,0.0001579689,0.000018052275,0.000042588745,0.0002770596,0.000020904012,0.0017227195],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997955,0.000052485713,0.000011333363,0.000035183984,0.00003449392,0.00007109068],"domain_scores_gemma":[0.99991465,0.000010857897,0.0000236589,0.000010114035,0.000012116441,0.000028662867],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019882373,0.00023879408,0.0003094731,0.00016867141,0.00018727759,0.00030944918,0.00013918344,0.00031628038,0.0013385391],"category_scores_gemma":[0.00016143586,0.00014039414,0.0005007982,0.00010358045,0.00027326014,0.0002669506,0.00027169028,0.00074769236,0.0004092223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00030972357,0.000022237236,0.00021388248,0.000026266316,0.0000045555607,0.00006020039,0.000012259411,0.00005288331,0.99807066,0.00009266001,0.000058524158,0.0010761428],"study_design_scores_gemma":[0.000089204485,0.00097598473,0.034208544,0.000012159151,0.000060065406,0.0006214111,0.000216919,0.0029738755,0.95519006,0.00033847246,0.005293779,0.000019495119],"about_ca_topic_score_codex":0.00086654106,"about_ca_topic_score_gemma":0.00092541444,"teacher_disagreement_score":0.0013385391,"about_ca_system_score_codex":0.00023777715,"about_ca_system_score_gemma":0.00020427986,"threshold_uncertainty_score":0.0044778585},"labels":[],"label_agreement":null},{"id":"W3118400986","doi":"10.22215/etd/2016-11700","title":"Regulation of the Nuclear Factor of Activated T Cell (NFAT) Family of Transcription Factors in the Freeze Tolerant Wood Frog, Rana sylvatica","year":2016,"lang":"en","type":"dissertation","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Carleton University; University of Ottawa","funders":"","keywords":"NFAT; Transcription factor; Cell biology; Biology; Cryoprotectant; Internal medicine; Biochemistry; Gene; Cryopreservation; Embryo","score_opus":0.012058018472195332,"score_gpt":0.22621744580194023,"score_spread":0.21415942732974488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3118400986","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917631,0.0025670053,0.001261021,0.00012910982,0.000029064466,0.000012471048,0.0004789154,0.000060503782,0.0036987497],"genre_scores_gemma":[0.98788655,0.0016909932,0.0008620653,0.0000614034,0.000013392328,0.0000271605,0.0009953649,0.000019315505,0.008443782],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999294,0.0000075284047,0.0000029863218,0.00002523929,0.000013654025,0.00002115503],"domain_scores_gemma":[0.99995196,0.000004378949,0.000016336971,0.0000033979993,0.000009377105,0.0000144906035],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007173976,0.00019203332,0.00010197513,0.00020042887,0.00027856932,0.00024336833,0.000112949354,0.00014863723,0.0013578766],"category_scores_gemma":[0.000057772566,0.00009144175,0.00020638174,0.00010229497,0.00020148714,0.00016118314,0.00016443268,0.0003351884,0.00034014886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011845665,0.00003316939,0.0017112251,0.000025774196,0.000005536092,0.0000962661,0.00009420403,0.000053261083,0.99516016,0.00026445132,0.00018163741,0.0022557562],"study_design_scores_gemma":[0.0000809279,0.0005153516,0.5307246,0.00006273623,0.00007820311,0.0012386681,0.00085493084,0.0019387509,0.44907108,0.0010483927,0.014351523,0.000034791792],"about_ca_topic_score_codex":0.0018593328,"about_ca_topic_score_gemma":0.004418391,"teacher_disagreement_score":0.0018593328,"about_ca_system_score_codex":0.0002234021,"about_ca_system_score_gemma":0.00015206623,"threshold_uncertainty_score":0.004542589},"labels":[],"label_agreement":null},{"id":"W3121527289","doi":"10.1016/j.yexcr.2021.112854","title":"NFATc1 promotes epithelial-mesenchymal transition and facilitates colorectal cancer metastasis by targeting SNAI1","year":2021,"lang":"en","type":"article","venue":"Experimental Cell Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Key Science and Technology Program of Shaanxi Province; Science and Technology Innovation as a Whole Plan Projects of Shaanxi Province; National Natural Science Foundation of China","keywords":"SNAI1; Epithelial–mesenchymal transition; Metastasis; Colorectal cancer; Biology; Cancer research; Slug; Cancer","score_opus":0.029670539322644747,"score_gpt":0.34641478150998123,"score_spread":0.3167442421873365,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3121527289","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9837621,0.0036505258,0.005503688,0.00087345735,0.00018886273,0.000039851802,0.00073383696,0.00034985004,0.0048979158],"genre_scores_gemma":[0.9919344,0.00095001544,0.002011621,0.00006226481,0.000021286967,0.00002923234,0.00043846443,0.000038348087,0.004514366],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997203,0.000034098466,0.000022679927,0.00005331891,0.000089719164,0.00007992659],"domain_scores_gemma":[0.9998246,0.000021562217,0.000046828347,0.000020461339,0.000019620833,0.00006690103],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002197951,0.0004239894,0.00021534514,0.00046200777,0.00039678637,0.00046942933,0.00030801192,0.00031906363,0.0035773776],"category_scores_gemma":[0.00018422266,0.00031766776,0.00032227146,0.0003338569,0.00045555335,0.00038217386,0.00024199137,0.0012457233,0.00074987113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023912486,0.00007288675,0.00030561295,0.00004892657,0.000007796125,0.000036602814,0.00002015957,0.00008897297,0.9968047,0.00034243154,0.00020163905,0.0018311726],"study_design_scores_gemma":[0.000043984623,0.0001792519,0.0038482025,0.0000057827524,0.00001924849,0.00020135831,0.00006011629,0.0014211563,0.9897042,0.00011511289,0.0043961075,0.0000055380006],"about_ca_topic_score_codex":0.0017158664,"about_ca_topic_score_gemma":0.0041921674,"teacher_disagreement_score":0.0035773776,"about_ca_system_score_codex":0.0006951788,"about_ca_system_score_gemma":0.000517961,"threshold_uncertainty_score":0.01196754},"labels":[],"label_agreement":null},{"id":"W3126302743","doi":"10.1002/2211-5463.13109","title":"Pin1 and JNK1 cooperatively modulate TAp63γ","year":2021,"lang":"en","type":"article","venue":"FEBS Open Bio","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pancreas Centre (Canada)","funders":"National Natural Science Foundation of China","keywords":"PIN1; Transactivation; Serine; Phosphorylation; Peptidylprolyl isomerase; Transcription factor; Gene isoform; Prolyl isomerase; Isomerase; Cell biology; Gene; Biology; Chemistry; Biochemistry","score_opus":0.023113520199262914,"score_gpt":0.28886442737456436,"score_spread":0.2657509071753014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3126302743","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.988952,0.003975989,0.0021517414,0.00019355166,0.0001018812,0.000052543874,0.00034184236,0.00011344402,0.0041171033],"genre_scores_gemma":[0.99440694,0.0013467872,0.0008873665,0.000097470176,0.000025140933,0.000056176697,0.00038104004,0.00001587327,0.002783234],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997434,0.00003480352,0.000017072252,0.000045067198,0.000054691933,0.00010499674],"domain_scores_gemma":[0.9998301,0.000024908866,0.00003460748,0.000012475777,0.000020652697,0.00007723288],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016066604,0.0007095253,0.00045633878,0.0002366576,0.00026774613,0.00047510193,0.0003649006,0.00030058424,0.0020457853],"category_scores_gemma":[0.00019836663,0.0002785858,0.00030232966,0.00013300046,0.00031230928,0.00038814766,0.0006564476,0.00068739796,0.0005485007],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006627996,0.00005321162,0.00026479474,0.00014448274,0.000009294748,0.00012913425,0.00002465522,0.000116696676,0.9965732,0.0001789331,0.00008782188,0.0017549365],"study_design_scores_gemma":[0.000051957497,0.0004589831,0.011928016,0.000009818902,0.0000350565,0.00041021625,0.000116012314,0.0020989904,0.9820033,0.00020291765,0.0026695128,0.000015219086],"about_ca_topic_score_codex":0.00045222702,"about_ca_topic_score_gemma":0.0007634778,"teacher_disagreement_score":0.0020457853,"about_ca_system_score_codex":0.0004155199,"about_ca_system_score_gemma":0.00027660004,"threshold_uncertainty_score":0.0068438053},"labels":[],"label_agreement":null},{"id":"W3130960303","doi":"10.21203/rs.3.rs-263770/v1","title":"Ezh2 as an epigenetic checkpoint regulator during monocyte differentiation: a potential target to improve cardiac repair after myocardial infarction","year":2021,"lang":"en","type":"preprint","venue":"Research Square","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"EZH2; Myocardial infarction; Epigenetics; Regulator; Monocyte; Cardiology; Medicine; Internal medicine; Cancer research; Master regulator; Biology; Transcription factor; Genetics; Gene","score_opus":0.014510786579961403,"score_gpt":0.3149223220118308,"score_spread":0.3004115354318694,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3130960303","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9653246,0.01969566,0.008914022,0.00092363387,0.00020084294,0.000056750334,0.00060324435,0.00024088423,0.004040454],"genre_scores_gemma":[0.9898357,0.0033236225,0.0017530919,0.00009617375,0.000058808626,0.00002630438,0.00034962202,0.000018654146,0.004538066],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999629,0.0000064386436,0.0000022033855,0.0000072492066,0.000008741427,0.000012591738],"domain_scores_gemma":[0.9999784,0.0000027959438,0.000005361405,0.0000027072817,0.00000315157,0.000007558723],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000120915116,0.0002187921,0.00028804567,0.00010935176,0.000081416314,0.00019198772,0.00010514354,0.00019279137,0.0024288541],"category_scores_gemma":[0.00006263919,0.000062938096,0.0001330351,0.000116305535,0.00013986287,0.00013519282,0.00015672078,0.00032070774,0.00034987225],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00076501555,0.000038541275,0.00056646793,0.00012217919,0.000012730259,0.00009480986,0.000010282413,0.00011237056,0.98968667,0.00030881152,0.00022884057,0.008053364],"study_design_scores_gemma":[0.0001294625,0.000601015,0.0119654015,0.00001181808,0.00005831532,0.0003999353,0.00002879133,0.000824902,0.9766232,0.00036070394,0.008989093,0.000007344089],"about_ca_topic_score_codex":0.00013751832,"about_ca_topic_score_gemma":0.00024453827,"teacher_disagreement_score":0.0024288541,"about_ca_system_score_codex":0.00012434008,"about_ca_system_score_gemma":0.00017322936,"threshold_uncertainty_score":0.008125365},"labels":[],"label_agreement":null},{"id":"W3132256210","doi":"10.1101/2021.02.22.432402","title":"Human basigin (CD147) does not directly interact with SARS-CoV-2 spike glycoprotein","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Medical Research Council; Wellcome Trust; Lister Institute of Preventive Medicine; University of Oxford","keywords":"Basigin; Glycoprotein; Biology; Plasmodium falciparum; Receptor; Recombinant DNA; Cell biology; Virology; Molecular biology; Genetics; Gene; Immunology; Malaria","score_opus":0.01540143194559903,"score_gpt":0.24734105178868715,"score_spread":0.2319396198430881,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3132256210","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99481755,0.001346346,0.001707987,0.0001562173,0.000027391809,0.000027120852,0.00029356434,0.000025983209,0.0015977684],"genre_scores_gemma":[0.99386793,0.00027490288,0.0016621304,0.00012452027,0.0000105135305,0.000020869586,0.0016452196,0.000008608047,0.0023852973],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99981064,0.000040544815,0.000012965194,0.000035910027,0.000062281084,0.000037588627],"domain_scores_gemma":[0.9999112,0.00003231604,0.000011866827,0.000016216223,0.000014041577,0.000014325693],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011744015,0.00017484132,0.000157318,0.00008988011,0.00010250169,0.00020810282,0.0001725816,0.0003381051,0.0015112536],"category_scores_gemma":[0.00023853626,0.00007272433,0.00022614181,0.000091027454,0.00011657079,0.00012192623,0.00017392516,0.0002859473,0.00047945944],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010376248,0.000026998325,0.00055703515,0.00003436161,0.000010970027,0.000068404224,0.000012854415,0.000047535115,0.9981103,0.000065255466,0.00011486862,0.00084767945],"study_design_scores_gemma":[0.000023415112,0.00032855844,0.009998935,0.000011837954,0.000020285068,0.0010019655,0.000041178362,0.0024545637,0.97859037,0.000051560306,0.0074713402,0.0000059138515],"about_ca_topic_score_codex":0.00096512586,"about_ca_topic_score_gemma":0.0008361098,"teacher_disagreement_score":0.0015112536,"about_ca_system_score_codex":0.00031021363,"about_ca_system_score_gemma":0.00011684868,"threshold_uncertainty_score":0.0050556064},"labels":[],"label_agreement":null},{"id":"W3132805840","doi":"10.1053/j.gastro.2021.02.039","title":"Beneficial Effect of Tacrolimus… Cyclosporin A, Still up for Discussion!","year":2021,"lang":"en","type":"letter","venue":"Gastroenterology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"West China Hospital, Sichuan University; Sichuan University; Fondation du CHUM","keywords":"Tacrolimus; Medicine; Internal medicine; Transplantation","score_opus":0.009455439361604144,"score_gpt":0.2529123161916267,"score_spread":0.24345687683002254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3132805840","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00091667427,0.009727095,0.00014045522,0.9468739,0.0388392,0.00000789557,0.00004857068,0.000028317549,0.003417821],"genre_scores_gemma":[0.013236093,0.008036377,0.00036314363,0.84258485,0.12656556,0.00003227252,0.00005744109,0.000026864804,0.009097463],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990533,0.0003087436,0.00009132616,0.00010662853,0.00029312295,0.00014687874],"domain_scores_gemma":[0.9979874,0.0011534354,0.00012455523,0.000073125244,0.00029840003,0.00036315227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0015688259,0.000538483,0.001100025,0.00035798212,0.0018191853,0.0018255893,0.00071155507,0.015490277,0.004551866],"category_scores_gemma":[0.00793585,0.00022940365,0.0009639169,0.00026316982,0.0018299617,0.0022334377,0.0005915888,0.01798621,0.0030462588],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00044442972,0.000077306795,0.00079103746,0.00015179171,0.00005146748,0.005719111,0.000051441373,0.00011283688,0.0006656199,0.0040764674,0.9573048,0.030553628],"study_design_scores_gemma":[0.0005684763,0.00021473425,0.0022731507,0.0003294632,0.00009814819,0.0071908007,0.00025664517,0.000443881,0.00070655375,0.016563613,0.9712805,0.00007395497],"about_ca_topic_score_codex":0.0017401833,"about_ca_topic_score_gemma":0.002512485,"teacher_disagreement_score":0.015490277,"about_ca_system_score_codex":0.002028326,"about_ca_system_score_gemma":0.0012780074,"threshold_uncertainty_score":0.015227497},"labels":[],"label_agreement":null},{"id":"W3133431458","doi":"10.1101/2021.02.24.431422","title":"The immunophilin protein FKBPL and its peptide derivatives are novel regulators of vascular integrity and inflammation via NF-κB signaling","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Proinflammatory cytokine; Inflammation; Cancer research; Phosphorylation; Tumor necrosis factor alpha; Pharmacology; Biology; Cytokine; Angiogenesis; Immunology; Cell biology","score_opus":0.011632721111464694,"score_gpt":0.21271526750108574,"score_spread":0.20108254638962106,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3133431458","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9696032,0.020959023,0.0053124945,0.00046415412,0.000107929,0.000034757057,0.0005419628,0.00013883173,0.0028377722],"genre_scores_gemma":[0.99284583,0.0032382524,0.0011419865,0.00009912742,0.00003415215,0.000025192427,0.00033703737,0.0000057839507,0.0022726841],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999521,0.000008611656,0.0000037902653,0.000009709688,0.0000129076825,0.00001295137],"domain_scores_gemma":[0.99995744,0.000003638615,0.000022015576,0.0000025045522,0.0000043187583,0.00001008307],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000074670206,0.0002659114,0.00014299755,0.00012996959,0.00012530907,0.00020974585,0.000095940064,0.00021266197,0.0010153223],"category_scores_gemma":[0.000051176525,0.00007000061,0.00016867688,0.00007733577,0.00015838123,0.00012654153,0.000114792194,0.00031385425,0.00028107094],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018621153,0.000014913218,0.00023780344,0.00007766198,0.000008185793,0.0001269874,0.000008157116,0.00006465058,0.9958085,0.00012953857,0.00012796508,0.0032093304],"study_design_scores_gemma":[0.00007532563,0.0008717334,0.024531495,0.000031190157,0.00006582825,0.0028572257,0.00004494597,0.001246771,0.95194566,0.00023431474,0.01807778,0.000017744082],"about_ca_topic_score_codex":0.00026606917,"about_ca_topic_score_gemma":0.00039481436,"teacher_disagreement_score":0.0010153223,"about_ca_system_score_codex":0.00022170729,"about_ca_system_score_gemma":0.00009257937,"threshold_uncertainty_score":0.0033966303},"labels":[],"label_agreement":null},{"id":"W3138058639","doi":"10.1038/s42003-021-01927-3","title":"Pin1 inhibition improves the efficacy of ralaniten compounds that bind to the N-terminal domain of androgen receptor","year":2021,"lang":"en","type":"article","venue":"Communications Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Genome British Columbia","funders":"CIHR Skin Research Training Centre; U.S. Department of Health and Human Services; Government of Canada; National Institutes of Health; National Cancer Institute; Canadian Institutes of Health Research","keywords":"Androgen receptor; PIN1; Prostate cancer; Cancer research; In vivo; Linker; Chemistry; Pharmacology; Androgen deprivation therapy; Androgen; Medicine; Biology; Hormone; Internal medicine; Cancer; Isomerase; Biochemistry; Enzyme; Computer science; Genetics","score_opus":0.03142241601383327,"score_gpt":0.3007933432108539,"score_spread":0.2693709271970206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3138058639","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98957634,0.0050075203,0.0010655548,0.0001983972,0.0001008632,0.00004492986,0.0004046535,0.0002698634,0.003331895],"genre_scores_gemma":[0.994166,0.0018404818,0.0006111613,0.00006580046,0.0000139877775,0.000020811956,0.0005063372,0.000016288745,0.0027590971],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989974,0.000013634167,0.0000053628546,0.000016487167,0.00002584095,0.000038948067],"domain_scores_gemma":[0.999956,0.00000758635,0.00000903424,0.0000042807524,0.0000043924015,0.000018598359],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000080349084,0.00032968752,0.0004099569,0.00026065396,0.00012408022,0.0003019264,0.00024842992,0.00016521425,0.0021974004],"category_scores_gemma":[0.000092507726,0.000094118426,0.0002145301,0.00013390127,0.00015170488,0.00017447994,0.00013940592,0.00074915227,0.0004235949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010409952,0.00031642115,0.00019674018,0.00011161913,0.000022817418,0.00006239961,0.000016468,0.0002204327,0.9839521,0.0001273666,0.0003999763,0.013532494],"study_design_scores_gemma":[0.00011789103,0.004264253,0.005153572,0.000009239991,0.000045742385,0.00037778306,0.000027659778,0.0008302181,0.9824639,0.000048268408,0.0066493815,0.00001200062],"about_ca_topic_score_codex":0.0006190139,"about_ca_topic_score_gemma":0.0017096407,"teacher_disagreement_score":0.0021974004,"about_ca_system_score_codex":0.0001977891,"about_ca_system_score_gemma":0.00022243863,"threshold_uncertainty_score":0.0073511004},"labels":[],"label_agreement":null},{"id":"W3152663054","doi":"10.1681/asn.2020081234","title":"A Rare Autosomal Dominant Variant in Regulator of Calcineurin Type 1 (RCAN1) Gene Confers Enhanced Calcineurin Activity and May Cause FSGS","year":2021,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"National Center for Advancing Translational Sciences; National Institute of Diabetes and Digestive and Kidney Diseases; Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; Kidney Research UK; Halpin Foundation; University of Michigan; Physicians' Services Incorporated Foundation; Nephcure Foundation; Doris Duke Charitable Foundation","keywords":"Calcineurin; NFAT; Podocyte; Biology; Regulator; Cancer research; Mutation; Nephrotic syndrome; Genetics; Gene; Internal medicine; Endocrinology; Medicine; Transplantation; Kidney","score_opus":0.0139445575022039,"score_gpt":0.2731312305540339,"score_spread":0.25918667305182996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3152663054","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99817646,0.00034851904,0.00049954175,0.00007192721,0.000010907337,0.000008854335,0.0002017487,0.000050911745,0.0006310118],"genre_scores_gemma":[0.9987925,0.00014253083,0.00050115143,0.000039387833,0.000015346366,0.000003982775,0.0001551213,0.000008942846,0.0003410562],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9998311,0.000021939964,0.0000157117,0.0000657259,0.000043248834,0.000022256816],"domain_scores_gemma":[0.99968374,0.00013727794,0.000097983386,0.00001985496,0.00001859333,0.000042602747],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00018617818,0.0008700034,0.00037811254,0.0008902497,0.00037528097,0.00022149282,0.0002941719,0.00058991794,0.0021362912],"category_scores_gemma":[0.00073644257,0.00013097833,0.00030601776,0.00053249317,0.00041043264,0.00011957429,0.0001977755,0.00029098277,0.00020169723],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011963147,0.00018966846,0.2688326,0.00030024664,0.0003558465,0.23587188,0.0008475467,0.0011109323,0.46869346,0.0013924941,0.0015394891,0.019669525],"study_design_scores_gemma":[0.00010668437,0.0004282753,0.48983988,0.000073685216,0.00034226803,0.4416291,0.00025519938,0.0023981994,0.05883689,0.00066089915,0.0053890757,0.000039793893],"about_ca_topic_score_codex":0.0012344351,"about_ca_topic_score_gemma":0.0018541225,"teacher_disagreement_score":0.0021362912,"about_ca_system_score_codex":0.00030539697,"about_ca_system_score_gemma":0.00020909293,"threshold_uncertainty_score":0.007146597},"labels":[],"label_agreement":null},{"id":"W3153201529","doi":"10.1164/rccm.202009-3545oc","title":"Secreted Extracellular Cyclophilin A Is a Novel Mediator of Ventilator-induced Lung Injury","year":2021,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Biotechnology and Biological Sciences Research Council; Medical Research Council; Directorate for Biological Sciences; Queen's University; Queen's University Belfast; Agency for Science, Technology and Research; Royal College of Anaesthetists; Academy of Medical Sciences; National Institute for Health and Care Research","keywords":"Cypa; Cyclophilin A; Pathogenesis; Extracellular; Medicine; Intracellular; Immunology; Bronchoalveolar lavage; Rheumatoid arthritis; Alveolar macrophage; Macrophage; Inflammation; Downregulation and upregulation; Lung; Cell biology; Cancer research; Biology; Gene; In vitro; Molecular biology; Internal medicine","score_opus":0.015503854120393443,"score_gpt":0.30769334358041317,"score_spread":0.2921894894600197,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3153201529","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825982,0.013030792,0.0020137369,0.0003417853,0.00007688559,0.000045478802,0.0004785212,0.000050211664,0.0013644038],"genre_scores_gemma":[0.99640214,0.0018235666,0.0005251381,0.00008952224,0.000068877176,0.000024706746,0.000342866,0.0000027133744,0.00072039757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999902,0.000025817924,0.00000831584,0.000021989197,0.000023692879,0.000018160104],"domain_scores_gemma":[0.9999032,0.0000111730305,0.000034852263,0.0000071803006,0.000013761003,0.000029916268],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011180321,0.0003009573,0.00018547705,0.0002794975,0.00014049606,0.00031710707,0.00011232008,0.00027062284,0.0012695779],"category_scores_gemma":[0.000106128384,0.00007010964,0.0002395932,0.00014371013,0.0001778789,0.00013416493,0.0002386641,0.00033826873,0.00019008173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00058840035,0.00004524857,0.008014102,0.0002088286,0.00005839695,0.0008886483,0.000026027967,0.00006581719,0.98464704,0.00019516639,0.00028307154,0.004979147],"study_design_scores_gemma":[0.00011877964,0.0018915312,0.4366454,0.00010310044,0.0002558547,0.00966353,0.00027667842,0.004255767,0.53533494,0.0005985063,0.010832411,0.000023575712],"about_ca_topic_score_codex":0.0002025869,"about_ca_topic_score_gemma":0.00019541163,"teacher_disagreement_score":0.0012695779,"about_ca_system_score_codex":0.00018286443,"about_ca_system_score_gemma":0.00010439336,"threshold_uncertainty_score":0.0042471886},"labels":[],"label_agreement":null},{"id":"W3154026021","doi":"10.3390/ijms22084118","title":"Cerebral Apolipoprotein D Exits the Brain and Accumulates in Peripheral Tissues","year":2021,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institut National de la Recherche Scientifique; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Réseau québécois de recherche sur le vieillissement","keywords":"Basigin; Lipocalin; Central nervous system; Biology; Apolipoprotein B; Peripheral; Pathology; Neuroprotection; Blood–brain barrier; Medicine; Endocrinology; Internal medicine; Neuroscience; Biochemistry; Cholesterol","score_opus":0.018265805274307968,"score_gpt":0.31389043641823255,"score_spread":0.29562463114392457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3154026021","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.990341,0.0022471638,0.004075086,0.00017007366,0.000038487175,0.00001774317,0.00047954536,0.00012686248,0.00250405],"genre_scores_gemma":[0.9865644,0.0021992975,0.002864842,0.0001337557,0.00001707825,0.000040332892,0.00074405957,0.000047419635,0.007388799],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999193,0.000006340577,0.0000053267995,0.00002638553,0.000017623954,0.000024941706],"domain_scores_gemma":[0.9999355,0.0000073575616,0.000014458492,0.000009492334,0.000016686707,0.000016490492],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000089482346,0.0002726751,0.00030884263,0.000225925,0.00017457729,0.0004409838,0.00013479314,0.00020897313,0.0012802425],"category_scores_gemma":[0.00011772561,0.000104230625,0.00020428785,0.00012523418,0.00020262129,0.00018357686,0.00018611694,0.00051818416,0.000506085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031646003,0.000021023352,0.00084891653,0.00007507443,0.000011727107,0.00035957524,0.00003923441,0.000028401655,0.99453497,0.00012899518,0.00014974567,0.0034859555],"study_design_scores_gemma":[0.000019786994,0.0002665936,0.020201903,0.000019022165,0.0000302009,0.0011561605,0.00016348452,0.00062444864,0.97448266,0.00022171535,0.0028041806,0.000009889484],"about_ca_topic_score_codex":0.0018513509,"about_ca_topic_score_gemma":0.0020097452,"teacher_disagreement_score":0.0018513509,"about_ca_system_score_codex":0.0004390495,"about_ca_system_score_gemma":0.00039576905,"threshold_uncertainty_score":0.004282832},"labels":[],"label_agreement":null},{"id":"W3158594742","doi":"10.1101/2020.06.08.129528","title":"Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia","year":2020,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Fondazione Regionale per la Ricerca Biomedica; Regione Lombardia; Ministero della Salute; E-Rare","keywords":"Amyotrophic lateral sclerosis; Frontotemporal dementia; Neurodegeneration; C9orf72; Biology; Neuroscience; Cell biology; Dementia; Medicine; Disease; Internal medicine","score_opus":0.026188322856995565,"score_gpt":0.23695918087884776,"score_spread":0.2107708580218522,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3158594742","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9971397,0.0011700339,0.00051625696,0.00011788772,0.000018913748,0.000015325206,0.00032481158,0.0000471089,0.00065000704],"genre_scores_gemma":[0.9984774,0.00037320243,0.00027163487,0.0000560182,0.000009340606,0.000015085523,0.0002173143,0.0000062609884,0.00057383924],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999367,0.000010424039,0.000009272571,0.000016433634,0.000016041502,0.000011083673],"domain_scores_gemma":[0.9999155,0.000011026811,0.000028018363,0.0000054808265,0.000006861482,0.000033098975],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009873711,0.00043200818,0.00019263371,0.0006042505,0.00021229201,0.0001670196,0.00013643241,0.0004413705,0.0010687842],"category_scores_gemma":[0.00008959797,0.000119519915,0.0002493005,0.00017991713,0.0002935253,0.00011721036,0.00021744179,0.0002657003,0.00021424882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00039818275,0.00008324388,0.0027626567,0.000036852234,0.000022979124,0.0017422346,0.000019004889,0.000060567683,0.99365073,0.0001471543,0.00007327628,0.0010030406],"study_design_scores_gemma":[0.00019367496,0.0013050814,0.3069459,0.000039696773,0.0002496118,0.028173402,0.00016411638,0.004026498,0.6531575,0.00087497936,0.004842373,0.000027268316],"about_ca_topic_score_codex":0.0006407233,"about_ca_topic_score_gemma":0.00057721906,"teacher_disagreement_score":0.0010687842,"about_ca_system_score_codex":0.00028411136,"about_ca_system_score_gemma":0.00013080584,"threshold_uncertainty_score":0.0035753846},"labels":[],"label_agreement":null},{"id":"W3159245202","doi":"10.1111/cge.13979","title":"<scp> <i>PPP3CA</i> </scp> truncating variants clustered in the regulatory domain cause early‐onset refractory epilepsy","year":2021,"lang":"en","type":"article","venue":"Clinical Genetics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; SickKids Foundation; Stollery Children's Hospital; Hospital for Sick Children; University of Toronto","funders":"National Human Genome Research Institute","keywords":"Missense mutation; Genetics; Biology; Frameshift mutation; Loss function; Epilepsy; Allele; Mutant; Mutation; Phenotype; Gene; Neuroscience","score_opus":0.0426213757449282,"score_gpt":0.32733825743014905,"score_spread":0.28471688168522086,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3159245202","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99432373,0.00028655518,0.0021614658,0.0001242382,0.000017894536,0.000034823246,0.00023493759,0.00006726313,0.0027491671],"genre_scores_gemma":[0.9986451,0.0000805645,0.00053648825,0.00006242117,0.000017951634,0.0000057826765,0.00012552024,0.00001137724,0.00051475054],"study_design_codex":"case_report","study_design_gemma":"observational","domain_scores_codex":[0.9998652,0.000017570172,0.000017632632,0.00004589268,0.000028615157,0.000025133233],"domain_scores_gemma":[0.999666,0.00008664606,0.00012443888,0.000021805396,0.000023729292,0.00007751237],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010550278,0.0008874954,0.0002827626,0.00047818173,0.0004035629,0.00022141893,0.0001986439,0.00037399164,0.0016441264],"category_scores_gemma":[0.00049073575,0.00014660787,0.0002902627,0.0002979846,0.00058419455,0.00015451564,0.00035135017,0.00039640622,0.00031390958],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063522026,0.0001492601,0.18386708,0.00012472791,0.00021836115,0.46094313,0.00078276923,0.00083056156,0.32373405,0.0011453521,0.0017545049,0.025815008],"study_design_scores_gemma":[0.00007184929,0.00033155864,0.26820096,0.000019917512,0.00010262522,0.6977561,0.00018235698,0.0006169169,0.029069312,0.00039302674,0.0032259016,0.00002941277],"about_ca_topic_score_codex":0.0011923999,"about_ca_topic_score_gemma":0.0013960885,"teacher_disagreement_score":0.0016441264,"about_ca_system_score_codex":0.00022053381,"about_ca_system_score_gemma":0.00020340233,"threshold_uncertainty_score":0.0055001974},"labels":[],"label_agreement":null},{"id":"W3166963116","doi":"10.1038/s41467-021-23496-z","title":"Structure and mechanism of the human NHE1-CHP1 complex","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Chinese Academy of Sciences; Institute of Biophysics, Chinese Academy of Sciences; National Natural Science Foundation of China; McGill University","keywords":"Chemistry; Intracellular pH; Transporter; Protein subunit; Biophysics; Conformational change; Cell biology; Intracellular; Biochemistry; Biology; Gene","score_opus":0.024668016717495363,"score_gpt":0.30746355745824544,"score_spread":0.2827955407407501,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3166963116","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825591,0.006498949,0.005274755,0.001026031,0.000044404886,0.00004113452,0.0006897367,0.000157696,0.0037082587],"genre_scores_gemma":[0.9904129,0.0016466258,0.002982779,0.00020808374,0.000020005846,0.000025839316,0.0018916216,0.000019576246,0.0027925794],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991894,0.000008092305,0.000003682983,0.000037593698,0.000016763213,0.000014900812],"domain_scores_gemma":[0.9999422,0.0000067306682,0.000017858552,0.000007081727,0.000007927467,0.000018188444],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008554532,0.00020796178,0.0001807461,0.00016639032,0.00037484564,0.00036266542,0.00042666701,0.00047125228,0.0017551808],"category_scores_gemma":[0.00016449887,0.00020659102,0.00018582332,0.00015058722,0.00022578266,0.00034753725,0.00024428475,0.00045780945,0.00054461986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00063986966,0.00007050663,0.0020914255,0.00024501138,0.0000421535,0.00057034957,0.0002387382,0.001677827,0.9819078,0.0033238977,0.0014682664,0.007724046],"study_design_scores_gemma":[0.00015778623,0.00038973588,0.044153724,0.0000745768,0.00008271937,0.003034563,0.00024099782,0.026271837,0.8832582,0.0025166157,0.039752357,0.00006677936],"about_ca_topic_score_codex":0.0013916217,"about_ca_topic_score_gemma":0.0009156011,"teacher_disagreement_score":0.0017551808,"about_ca_system_score_codex":0.00082000083,"about_ca_system_score_gemma":0.00020234329,"threshold_uncertainty_score":0.005949497},"labels":[],"label_agreement":null},{"id":"W3170949827","doi":"10.2139/ssrn.3858052","title":"The Immunophilin Protein FKBPL and its Peptide Derivatives are Novel Regulators of Vascular Integrity and Inflammation via Nf-κB Signaling","year":2021,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Inflammation; Peptide; Signal transduction; Cell biology; Chemistry; Biology; Biochemistry; Computational biology; Immunology","score_opus":0.007464525360229214,"score_gpt":0.2235785341444865,"score_spread":0.2161140087842573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3170949827","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97369313,0.01664471,0.0053637656,0.0004925816,0.000088398425,0.00001825165,0.00045595158,0.00015551943,0.0030876438],"genre_scores_gemma":[0.99243575,0.0030872866,0.0016828555,0.00010251074,0.000036252844,0.000012428067,0.0004270546,0.000011434148,0.0022044408],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999281,0.000012316477,0.0000047733056,0.00001931326,0.00001930967,0.000016131662],"domain_scores_gemma":[0.99994326,0.000005110432,0.00003010364,0.000003577496,0.000004989669,0.000012883501],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010488298,0.0002742896,0.00021322294,0.00019400807,0.00017395352,0.00037524092,0.00014074479,0.00027310752,0.000887407],"category_scores_gemma":[0.00009818269,0.00008613082,0.00015912266,0.0001171718,0.00021800913,0.00020749793,0.0001799475,0.00039779703,0.00030309707],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003810351,0.000013951188,0.0007734169,0.00006911976,0.000015927699,0.0003065289,0.000014712769,0.00013839352,0.9921405,0.00041255588,0.00017894515,0.0055548325],"study_design_scores_gemma":[0.000088841145,0.0006712906,0.05706445,0.00002586875,0.00010214013,0.0046058306,0.00008983722,0.002626053,0.91562736,0.00078126177,0.018277023,0.000039984694],"about_ca_topic_score_codex":0.00031244033,"about_ca_topic_score_gemma":0.00052013935,"teacher_disagreement_score":0.000887407,"about_ca_system_score_codex":0.0003939885,"about_ca_system_score_gemma":0.00012759604,"threshold_uncertainty_score":0.0029686093},"labels":[],"label_agreement":null},{"id":"W3174184755","doi":"10.1096/fasebj.26.1_supplement.963.7","title":"ATP alters IKK‐2 inhibitor affinity for IKK2 enzyme and reveals non‐equivalent inhibitor binding sites","year":2012,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Gilead Sciences (Canada)","funders":"","keywords":"IC50; Chemistry; Potency; Enzyme; Enzyme assay; Biochemistry; In vitro","score_opus":0.029890383364543954,"score_gpt":0.27813875755038103,"score_spread":0.2482483741858371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3174184755","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9649254,0.0024745457,0.020492375,0.00029685555,0.0002597097,0.00018149585,0.0022837676,0.0003877641,0.0086980825],"genre_scores_gemma":[0.97726464,0.00096001953,0.010829547,0.00017792989,0.00003054196,0.00031147513,0.0025200737,0.00014557254,0.007760271],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992536,0.000090277084,0.00008978545,0.00018204185,0.00022739594,0.00015688068],"domain_scores_gemma":[0.9996296,0.00014101256,0.00007740554,0.000049302285,0.000056144334,0.000046454996],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004033998,0.00044599638,0.00040191028,0.00022719103,0.00020711802,0.00069883117,0.00048097395,0.00053208525,0.009141989],"category_scores_gemma":[0.0006602857,0.00032038655,0.00027179884,0.00028163585,0.00029933456,0.0003894288,0.00019663453,0.0011497665,0.0014256686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004659415,0.00011330907,0.00026708242,0.000082505045,0.000009291151,0.00004071443,0.000016977154,0.00013972362,0.9965753,0.00016754749,0.00022036917,0.0019012308],"study_design_scores_gemma":[0.000037801765,0.00029665584,0.0030631097,0.000007067686,0.000014667228,0.00015891097,0.000018065963,0.00089785387,0.9936434,0.00004442801,0.0018097503,0.000008209206],"about_ca_topic_score_codex":0.0011905193,"about_ca_topic_score_gemma":0.0019713775,"teacher_disagreement_score":0.009141989,"about_ca_system_score_codex":0.0007082566,"about_ca_system_score_gemma":0.0005095884,"threshold_uncertainty_score":0.030582964},"labels":[],"label_agreement":null},{"id":"W3176472307","doi":"10.1096/fasebj.2019.33.1_supplement.868.10","title":"Activating the MasR/Ang1‐7 Pathway Reduces Muscle Atrophy and Function Loss Following Denervation","year":2019,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Denervation; Atrophy; Muscle atrophy; Medicine; Internal medicine; Sciatic nerve; Endocrinology; Anatomy","score_opus":0.010440044326179586,"score_gpt":0.22152357267252498,"score_spread":0.2110835283463454,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3176472307","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9963955,0.0017261568,0.00069230556,0.00010610619,0.00006387861,0.000036007805,0.00021457992,0.00007890273,0.0006865493],"genre_scores_gemma":[0.98794323,0.0032881694,0.0015940327,0.00013809973,0.000043339456,0.00011377315,0.0007623606,0.000023182412,0.0060939314],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998486,0.000017427963,0.000016676699,0.00002050338,0.00003497502,0.00006180742],"domain_scores_gemma":[0.999843,0.0000157612,0.0000442648,0.000010780409,0.000019559224,0.0000666145],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014013961,0.0004368946,0.000568259,0.00035776873,0.00013743625,0.00019972684,0.00034031124,0.00038291744,0.0012608436],"category_scores_gemma":[0.00010674211,0.00019540454,0.00033992602,0.000119430144,0.0002693854,0.00028419614,0.00015425745,0.001009686,0.00026701653],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014172108,0.00044564757,0.00032529936,0.00010316163,0.000020219504,0.000046885227,0.00001865889,0.00009288359,0.9948112,0.00004001332,0.000091894566,0.0025871196],"study_design_scores_gemma":[0.00027446199,0.012366348,0.017641904,0.000041355957,0.00014200223,0.00023877731,0.00015582427,0.001367591,0.9651693,0.0000671495,0.0025200571,0.0000152543225],"about_ca_topic_score_codex":0.0005701722,"about_ca_topic_score_gemma":0.0016236688,"teacher_disagreement_score":0.0012608436,"about_ca_system_score_codex":0.00016114042,"about_ca_system_score_gemma":0.00025902732,"threshold_uncertainty_score":0.0042179823},"labels":[],"label_agreement":null},{"id":"W3177371933","doi":"10.1096/fasebj.25.1_supplement.1059.16","title":"The NFATc2 transcription factor is required for normal heart function and signaling in adult mice","year":2011,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Chesapeake Research Consortium","keywords":"NFAT; Calcineurin; Transcription factor; Internal medicine; Muscle hypertrophy; Endocrinology; Protein kinase B; Biology; Ventricle; Cell biology; Signal transduction; Medicine; Transplantation; Genetics","score_opus":0.029932583742416075,"score_gpt":0.2419033103338419,"score_spread":0.21197072659142582,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3177371933","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9289351,0.0056975274,0.029789008,0.0019435311,0.0005301126,0.00033839745,0.013150577,0.0025749383,0.01704088],"genre_scores_gemma":[0.9192288,0.0033594738,0.023084836,0.0005158289,0.00023065304,0.0006540949,0.010821853,0.0010597096,0.041044716],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9993222,0.000088823916,0.00007619222,0.00019807211,0.0001976076,0.00011709683],"domain_scores_gemma":[0.99893135,0.00006603666,0.00035276153,0.00014089914,0.00009459476,0.0004144065],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00048684393,0.0010621141,0.0004957989,0.0012032819,0.0006046918,0.00072839326,0.0008878439,0.0010668773,0.00788442],"category_scores_gemma":[0.00041135095,0.00054921553,0.00066287967,0.00038330368,0.00072103937,0.00051792245,0.0005186848,0.0016148516,0.0024509658],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00067854393,0.00012210598,0.00066553423,0.000086024455,0.000021065423,0.0003598197,0.000054873755,0.0000821165,0.99290234,0.0006346661,0.00042130705,0.0039715404],"study_design_scores_gemma":[0.000918295,0.0014664343,0.046061575,0.00023663903,0.0001966313,0.008761968,0.00022675397,0.003472103,0.86383283,0.0014399518,0.07331729,0.00006969619],"about_ca_topic_score_codex":0.0015292736,"about_ca_topic_score_gemma":0.0022049663,"teacher_disagreement_score":0.00788442,"about_ca_system_score_codex":0.00075760944,"about_ca_system_score_gemma":0.00072281365,"threshold_uncertainty_score":0.026376009},"labels":[],"label_agreement":null},{"id":"W3178399873","doi":"10.1101/2021.07.14.451536","title":"Palmitoylation targets the Calcineurin phosphatase to the Phosphatidylinositol 4-kinase complex at the plasma membrane","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital; University of British Columbia; Lunenfeld-Tanenbaum Research Institute; University of Victoria","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Natural Sciences and Engineering Research Council of Canada; National Institute of Child Health and Human Development; Canadian Institutes of Health Research; Nemzeti Kutatási, Fejlesztési és Innovaciós Alap; National Institutes of Health; Michael Smith Health Research BC","keywords":"Calcineurin; Palmitoylation; Phosphatase; Cell biology; Biology; Biochemistry; Phosphatidylinositol; Pleckstrin homology domain; Kinase; Phosphorylation; Chemistry; Enzyme","score_opus":0.015591409899825668,"score_gpt":0.23258233621489785,"score_spread":0.2169909263150722,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3178399873","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9907898,0.0013286532,0.0053513125,0.0002750829,0.000041227402,0.000015751888,0.00021703912,0.00007021731,0.0019109574],"genre_scores_gemma":[0.9927746,0.000929443,0.0026610747,0.0000708595,0.000008739535,0.000011981217,0.00027004222,0.00001599353,0.0032571477],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993265,0.000009301885,0.000004309033,0.000019533407,0.000018481145,0.0000157399],"domain_scores_gemma":[0.99996316,0.000004817174,0.000012244834,0.000005804385,0.000004196408,0.000009724409],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010435344,0.00021862904,0.00010852486,0.000109625085,0.00023228319,0.00026574463,0.00018804829,0.00019972169,0.0011449002],"category_scores_gemma":[0.000080573285,0.000100535144,0.00012316745,0.000098557815,0.0002254617,0.00018831168,0.00023838846,0.00030654075,0.00033035487],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051476985,0.0000046130976,0.00014632243,0.000015122102,0.0000027034462,0.00004226877,0.0000059698946,0.00007716476,0.9988417,0.00021122459,0.000030655174,0.00057090714],"study_design_scores_gemma":[0.000010826957,0.000034651086,0.0032227244,0.0000037166876,0.0000057882926,0.00019400728,0.000017696288,0.001227946,0.99231285,0.00018042968,0.0027863225,0.0000029817354],"about_ca_topic_score_codex":0.0009849829,"about_ca_topic_score_gemma":0.0013274192,"teacher_disagreement_score":0.0011449002,"about_ca_system_score_codex":0.00053126784,"about_ca_system_score_gemma":0.00021061038,"threshold_uncertainty_score":0.0038546324},"labels":[],"label_agreement":null},{"id":"W3184091950","doi":"10.3390/pathogens10070902","title":"Cyclophilins and Their Roles in Hepatitis C Virus and Flavivirus Infections: Perspectives for Novel Antiviral Approaches","year":2021,"lang":"en","type":"review","venue":"Pathogens","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Virology; Flavivirus; Biology; Hepatitis C virus; Viral replication; Dengue virus; Flaviviridae; Cyclophilin; Cyclophilin A; Virus; Daclatasvir; Immunology; Genetics","score_opus":0.05520585656252743,"score_gpt":0.3009062321002116,"score_spread":0.24570037553768417,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3184091950","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00011835743,0.9978975,0.00015014023,0.000439092,0.00038038858,0.00000288622,0.000013232194,0.000007805804,0.0009905553],"genre_scores_gemma":[0.0006512434,0.99770665,0.00016234053,0.00022668693,0.0003094982,0.000004395643,0.00003182754,0.0000013606435,0.00090604054],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998925,0.000021724603,0.000012832572,0.00001737388,0.00003954245,0.000015922367],"domain_scores_gemma":[0.9997702,0.00009421458,0.000026206417,0.000008094242,0.00006216813,0.00003899799],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004314022,0.00073588203,0.0008078299,0.0014543869,0.00025129793,0.0007790357,0.00060220086,0.0010542822,0.0038969396],"category_scores_gemma":[0.00044041142,0.00017188281,0.00034986145,0.0011814107,0.0003895719,0.0012430181,0.0006233628,0.0020245807,0.0018813933],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000095785734,0.00006346115,0.00017557446,0.008120772,0.00006456794,0.00022566857,0.000044859073,0.00033608667,0.0035671254,0.0061456673,0.03959815,0.94156235],"study_design_scores_gemma":[0.000011767956,0.00008852664,0.0006135551,0.0013258669,0.000055918368,0.00089174946,0.000034660326,0.00008047201,0.0004765443,0.0020110032,0.9943984,0.000011528364],"about_ca_topic_score_codex":0.00063824817,"about_ca_topic_score_gemma":0.0012342322,"teacher_disagreement_score":0.0038969396,"about_ca_system_score_codex":0.0005286895,"about_ca_system_score_gemma":0.0009777192,"threshold_uncertainty_score":0.013036609},"labels":[],"label_agreement":null},{"id":"W3187427232","doi":"10.1016/j.jbc.2021.100987","title":"CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-β1","year":2021,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Medical Research Council; Cardiff University","keywords":"Myofibroblast; CD44; Cell biology; Transforming growth factor; Proinflammatory cytokine; Extracellular matrix; Fibroblast; Biology; Fibrosis; Cancer research; Immunology; Cell culture; Cell; Pathology; Inflammation; Medicine; Biochemistry","score_opus":0.014028151110017185,"score_gpt":0.23603504321370203,"score_spread":0.22200689210368485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3187427232","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9932371,0.0012985496,0.0026563888,0.00015045893,0.000041080573,0.0000436106,0.0002013311,0.00006409823,0.0023072977],"genre_scores_gemma":[0.99309677,0.0006727415,0.0017352789,0.00007564503,0.00002010246,0.000047823745,0.00063225586,0.000021632912,0.0036978545],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998097,0.00003145374,0.000014629608,0.00002770002,0.000048662827,0.00006784387],"domain_scores_gemma":[0.9998964,0.000012476521,0.000029823683,0.000012431093,0.000017570133,0.000031405903],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015771076,0.00023214945,0.00022399223,0.00015663532,0.00019963032,0.00025514627,0.00015076093,0.00022229063,0.0018143117],"category_scores_gemma":[0.00013861273,0.00015191376,0.0002927135,0.00008467859,0.00015109063,0.00015607697,0.0002554006,0.00036387442,0.0007698522],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051145395,0.000016583524,0.000118855154,0.000030663345,0.000002039255,0.00005411064,0.000011025108,0.000012373715,0.9989385,0.00009204617,0.000050690494,0.00062212104],"study_design_scores_gemma":[0.000019003492,0.00011600964,0.0069253994,0.000009661309,0.000008467602,0.00046045898,0.000034261884,0.0014141671,0.98808295,0.00005040457,0.0028760757,0.0000031488498],"about_ca_topic_score_codex":0.00037478667,"about_ca_topic_score_gemma":0.0005591932,"teacher_disagreement_score":0.0018143117,"about_ca_system_score_codex":0.00026900633,"about_ca_system_score_gemma":0.00018832783,"threshold_uncertainty_score":0.0060694814},"labels":[],"label_agreement":null},{"id":"W3190598927","doi":"10.1128/msphere.00647-21","title":"Human Basigin (CD147) Does Not Directly Interact with SARS-CoV-2 Spike Glycoprotein","year":2021,"lang":"en","type":"article","venue":"mSphere","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; UK Research and Innovation; Government of Canada; Wellcome Trust; Medical Research Council; Wellcome","keywords":"Basigin; Coronavirus disease 2019 (COVID-19); Spike (software development); Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Glycoprotein; 2019-20 coronavirus outbreak; Virology; Medicine; Intensive care medicine; Spike Protein; Computer science; Biology; Disease; Outbreak; Infectious disease (medical specialty); Internal medicine","score_opus":0.015752260998321672,"score_gpt":0.27493383190941617,"score_spread":0.2591815709110945,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3190598927","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98964685,0.002347343,0.0021801433,0.00040153268,0.000043429016,0.000023062226,0.00033820196,0.00003446314,0.0049850387],"genre_scores_gemma":[0.9934155,0.00043209828,0.0011854334,0.00017287608,0.000011742597,0.000010377611,0.00088609,0.000009270185,0.0038767224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998858,0.000022591239,0.0000045646593,0.00002256097,0.00003223027,0.00003229898],"domain_scores_gemma":[0.99995184,0.000013071731,0.000009243107,0.000008978682,0.00000520014,0.000011571682],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000090737565,0.00015105173,0.00015644112,0.00006152844,0.00010612372,0.00022920297,0.00021731078,0.00034707057,0.002465818],"category_scores_gemma":[0.00015659351,0.000067682224,0.00019317135,0.000051902254,0.00012801784,0.00016597327,0.00015505214,0.00029915993,0.0006816529],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019971002,0.000029888659,0.0009693365,0.00004051161,0.000016573915,0.00015974347,0.000019155996,0.000111216876,0.9948144,0.00037524223,0.00027621712,0.0029880994],"study_design_scores_gemma":[0.000035436897,0.00039150033,0.011798481,0.0000118714825,0.000022404105,0.0021608744,0.00004869819,0.0025284153,0.9648233,0.0001933025,0.017978026,0.000007654096],"about_ca_topic_score_codex":0.001205336,"about_ca_topic_score_gemma":0.001328684,"teacher_disagreement_score":0.002465818,"about_ca_system_score_codex":0.0003746779,"about_ca_system_score_gemma":0.00017208059,"threshold_uncertainty_score":0.008248985},"labels":[],"label_agreement":null},{"id":"W3206693297","doi":"10.1038/s41467-021-26326-4","title":"Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Wind Energy Institute of Canada; University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; University of British Columbia; University of Victoria","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Office of Extramural Research, National Institutes of Health; National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; National Institute of Child Health and Human Development; Canadian Institutes of Health Research; U.S. Department of Health and Human Services; Government of Canada; National Institutes of Health; Michael Smith Health Research BC","keywords":"Calcineurin; Palmitoylation; Phosphatase; Cell biology; Biology; Pleckstrin homology domain; Biochemistry; Phosphatidylinositol; Phosphatidylinositol 4,5-bisphosphate; Kinase; Phosphorylation; Chemistry; Enzyme","score_opus":0.022502940925839196,"score_gpt":0.29900662614212054,"score_spread":0.2765036852162813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3206693297","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97808707,0.0066588377,0.010611663,0.0003887568,0.000090359616,0.000035288882,0.0005225842,0.00013851051,0.003466857],"genre_scores_gemma":[0.98719656,0.0036691162,0.0048364326,0.00009203148,0.00001581137,0.000016029211,0.00046806733,0.000023467119,0.003682574],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998902,0.000013241407,0.0000065819954,0.00003489944,0.000035917205,0.0000192193],"domain_scores_gemma":[0.99993956,0.0000074495047,0.00002114026,0.000010065222,0.000008849729,0.000013006014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014092406,0.0003497204,0.00018949686,0.00019080153,0.0003088971,0.00043201743,0.00022739239,0.0002520675,0.0013312947],"category_scores_gemma":[0.00012509752,0.00012208213,0.00022355445,0.000208611,0.00029273552,0.00034203441,0.00031765475,0.00041391782,0.00033229875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006475447,0.0000060297257,0.00048013715,0.00003833902,0.00000975951,0.00008291809,0.000010659986,0.000088728186,0.9968838,0.00029630013,0.00003379953,0.0020047324],"study_design_scores_gemma":[0.000007938181,0.00005567114,0.0050121835,0.000005308614,0.000013530488,0.00049300387,0.000024804345,0.0008594037,0.98699385,0.00023750198,0.0062918984,0.0000049692026],"about_ca_topic_score_codex":0.0012258849,"about_ca_topic_score_gemma":0.0020449648,"teacher_disagreement_score":0.0013312947,"about_ca_system_score_codex":0.0005771261,"about_ca_system_score_gemma":0.00034696553,"threshold_uncertainty_score":0.004453659},"labels":[],"label_agreement":null},{"id":"W3209937759","doi":"10.5281/zenodo.4731002","title":"Antibody Characterization Report for Sequestosome-1","year":2021,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Characterization (materials science); Sequestosome 1; Antibody; Medicine; Immunology; Materials science; Nanotechnology","score_opus":0.028410526210892708,"score_gpt":0.27982002736738326,"score_spread":0.2514095011564906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3209937759","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.3730849,0.054149706,0.44750756,0.004085684,0.0038788205,0.0033845871,0.06451595,0.005665091,0.043727715],"genre_scores_gemma":[0.2717552,0.04335518,0.21609563,0.0021655532,0.0012611849,0.0035053196,0.3905874,0.0015907967,0.069683746],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99926335,0.00007448568,0.00010426805,0.00019264901,0.00021987951,0.00014536669],"domain_scores_gemma":[0.99905485,0.00017607484,0.00011135082,0.00015608384,0.0003577909,0.00014382874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00056920055,0.001680084,0.0008853117,0.0018028746,0.0009548768,0.00074965536,0.0013180205,0.00077812636,0.014920935],"category_scores_gemma":[0.0011085073,0.0006562671,0.001079065,0.0014059854,0.00025768168,0.00086433644,0.00059587654,0.0015766706,0.01640564],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021954937,0.00009345667,0.00027035028,0.000473265,0.00003769277,0.000232494,0.00004906107,0.00007922682,0.9837388,0.0006590959,0.005178777,0.00896824],"study_design_scores_gemma":[0.00007974453,0.0005463027,0.006326111,0.00009326131,0.00014331665,0.004391895,0.0000738432,0.0009666612,0.75367606,0.0005239811,0.23312506,0.00005371464],"about_ca_topic_score_codex":0.001201291,"about_ca_topic_score_gemma":0.001635472,"teacher_disagreement_score":0.014920935,"about_ca_system_score_codex":0.0006221825,"about_ca_system_score_gemma":0.0009694887,"threshold_uncertainty_score":0.049915433},"labels":[],"label_agreement":null},{"id":"W3216722889","doi":"10.7554/elife.72881.sa1","title":"Decision letter: DAAM mediates the assembly of long-lived, treadmilling stress fibers in collectively migrating epithelial cells in Drosophila","year":2021,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Cell biology; Treadmilling; Drosophila (subgenus); Biology; Chemistry; Biophysics; Genetics; Gene; Cell; Cytoskeleton","score_opus":0.02170445092897157,"score_gpt":0.291408870826997,"score_spread":0.26970441989802546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3216722889","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018332812,0.0013902714,0.0011393507,0.42811686,0.5146795,0.0003654212,0.0018552028,0.0007480918,0.049872003],"genre_scores_gemma":[0.026803043,0.00312961,0.0029192155,0.18697727,0.21052693,0.00041527866,0.0022402755,0.00076283235,0.56622547],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99299014,0.0008889487,0.0005297431,0.0005182922,0.0040523782,0.0010204354],"domain_scores_gemma":[0.95715237,0.009158322,0.0013628697,0.0019005268,0.021581208,0.008844659],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006787305,0.0006022806,0.0014912687,0.0013897438,0.003745444,0.0059480914,0.002463042,0.015633835,0.10676567],"category_scores_gemma":[0.05445591,0.0006637672,0.0009487767,0.0006516802,0.0017000579,0.002614976,0.002153671,0.0076054055,0.06136576],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008476319,0.000020198737,0.000097620556,0.00006004342,0.000007165537,0.00021181857,0.00001769305,0.000024731728,0.00022567717,0.0010070093,0.9921009,0.0061424654],"study_design_scores_gemma":[0.00008819835,0.000034514145,0.0010971847,0.000098615856,0.000011600495,0.00018528831,0.00006797887,0.00038000967,0.00068151805,0.0018216604,0.9955022,0.000031302818],"about_ca_topic_score_codex":0.0031785122,"about_ca_topic_score_gemma":0.00815255,"teacher_disagreement_score":0.10676567,"about_ca_system_score_codex":0.003281183,"about_ca_system_score_gemma":0.0070696073,"threshold_uncertainty_score":0.35716677},"labels":[],"label_agreement":null},{"id":"W3217561570","doi":"10.1159/000520040","title":"Calcineurin Aα Contributes to IgE-Dependent Mast-Cell Mediator Secretion in Allergic Inflammation","year":2021,"lang":"en","type":"article","venue":"Journal of Innate Immunity","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Izaak Walton Killam Health Centre; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Calcineurin; Immunoglobulin E; Mast cell; Cell biology; Allergic inflammation; Receptor; Inflammation; Chemistry; Signal transduction; Immunology; Biology; Molecular biology; Biochemistry; Antibody; Transplantation; Medicine; Internal medicine","score_opus":0.009265971848610197,"score_gpt":0.24875919375965394,"score_spread":0.23949322191104375,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3217561570","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95731014,0.031400677,0.008456514,0.00044671024,0.00015372824,0.00009944409,0.00020645617,0.0001432831,0.001783033],"genre_scores_gemma":[0.9900766,0.007064076,0.0014486411,0.00006577944,0.000058828828,0.000026419051,0.00011516818,0.000009585406,0.0011349809],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998585,0.000017455315,0.000019776295,0.00003510181,0.000043501484,0.000025670552],"domain_scores_gemma":[0.9997944,0.00001645871,0.00006915011,0.000020364732,0.000032763845,0.000066894805],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022667111,0.0007552635,0.00039023798,0.0003367325,0.0002748726,0.000414682,0.00036429716,0.0005079323,0.00055928563],"category_scores_gemma":[0.00020080745,0.0001975501,0.0003802786,0.00016889963,0.00053556275,0.00047525798,0.00032366722,0.0006714234,0.00017587768],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033433738,0.00005796395,0.0010358787,0.00015718685,0.000014836019,0.00048918143,0.00004028581,0.00011003686,0.99534214,0.00032230048,0.000045650893,0.002050188],"study_design_scores_gemma":[0.00021778798,0.0010934188,0.08520741,0.00009515631,0.0003133773,0.006142368,0.00020726926,0.0053748633,0.8860973,0.0020846531,0.013131585,0.000034796692],"about_ca_topic_score_codex":0.000648274,"about_ca_topic_score_gemma":0.0004549211,"teacher_disagreement_score":0.0007552635,"about_ca_system_score_codex":0.00032984442,"about_ca_system_score_gemma":0.000346403,"threshold_uncertainty_score":0.0023931265},"labels":[],"label_agreement":null},{"id":"W36081067","doi":"10.1007/978-0-387-09552-3_12","title":"Identifying the Cellular and Molecular Events Associated with the Divergent Phenotypes of Cardiac Hypertrophy","year":2008,"lang":"en","type":"book-chapter","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"","keywords":"Muscle hypertrophy; Phenotype; Cardiac myocyte; Pathological; Biology; Gene isoform; Myocyte; Cardiac hypertrophy; Ventricular hypertrophy; Phosphatidylinositol; Internal medicine; Cell biology; Signal transduction; Endocrinology; Left ventricular hypertrophy; Medicine; Genetics; Gene","score_opus":0.013400729801231385,"score_gpt":0.20330460106748946,"score_spread":0.18990387126625807,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W36081067","genre_codex":"review","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16593078,0.5313727,0.16977194,0.008727023,0.002260182,0.0002726715,0.0014131193,0.0010366418,0.11921491],"genre_scores_gemma":[0.32890835,0.3998226,0.15257497,0.003435656,0.0015690764,0.00044382527,0.0023833048,0.00029987734,0.11056233],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998914,0.000010873436,0.000006747827,0.000028621911,0.00004090023,0.000021418042],"domain_scores_gemma":[0.9998797,0.000056692614,0.000014632949,0.000011475132,0.000020319712,0.000017234297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00034904506,0.00062677095,0.0007147136,0.0008687923,0.0003066343,0.0012592654,0.0009050519,0.00090240536,0.0025342978],"category_scores_gemma":[0.00022848684,0.00036981908,0.0005611083,0.00077060744,0.00089871744,0.0015041383,0.00074873795,0.002701928,0.0012894345],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022785492,0.00008375834,0.00062264485,0.0006746748,0.000023896817,0.0007650538,0.00020694795,0.0007733098,0.8159664,0.04703785,0.0041067237,0.12951094],"study_design_scores_gemma":[0.000056762718,0.00038897112,0.021420695,0.00033486987,0.00014611756,0.0098336665,0.00057640194,0.0034768148,0.5708073,0.10329382,0.2895467,0.0001178611],"about_ca_topic_score_codex":0.00042821394,"about_ca_topic_score_gemma":0.00079155,"teacher_disagreement_score":0.0025342978,"about_ca_system_score_codex":0.0005782182,"about_ca_system_score_gemma":0.00035230172,"threshold_uncertainty_score":0.008478105},"labels":[],"label_agreement":null},{"id":"W40315891","doi":"10.1161/circ.124.suppl_21.a17281","title":"Abstract 17281: Programmed Necrosis of Ventricular Myocytes During Ischemic Stress Involves a Mitochondrial Regulated Bnip3- RIP-1- Cyclophilin D Signaling Pathway","year":2011,"lang":"en","type":"article","venue":"Circulation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Boniface Hospital","funders":"","keywords":"Medicine; Myocyte; Cell biology; Cyclophilin A; Mitochondrion; Necrosis; Signal transduction; Cardiology; Neuroscience; Internal medicine; Molecular biology; Biology","score_opus":0.018984047408866923,"score_gpt":0.2218016471055685,"score_spread":0.20281759969670157,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W40315891","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95762527,0.011128665,0.008929717,0.0018493092,0.00066161953,0.00027680324,0.005673895,0.00063688756,0.013217791],"genre_scores_gemma":[0.9602351,0.0062583033,0.0080818795,0.0008723924,0.0003441437,0.0003956237,0.0078778695,0.00008958802,0.015845116],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988186,0.000016073514,0.000016452175,0.000029869732,0.000028526234,0.0000272932],"domain_scores_gemma":[0.99992466,0.000012674468,0.000020507972,0.0000065678005,0.000008374923,0.000027225631],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015609425,0.000734175,0.0004257823,0.00020143104,0.00026165342,0.0002642308,0.0002821597,0.00041985934,0.006269531],"category_scores_gemma":[0.00010233019,0.0001365928,0.0002763971,0.00022964198,0.00027956386,0.000307876,0.0003228921,0.00093377143,0.0015854026],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007066662,0.00005232418,0.00010172068,0.00024070959,0.000010637968,0.00024834153,0.000012856682,0.000039093477,0.9958348,0.00018020939,0.000322027,0.002250422],"study_design_scores_gemma":[0.00037808067,0.0010402615,0.016626311,0.000049633654,0.000060451155,0.0017260861,0.00005103646,0.0010711503,0.9678696,0.00034386312,0.010770024,0.000013508519],"about_ca_topic_score_codex":0.00030966848,"about_ca_topic_score_gemma":0.0002941032,"teacher_disagreement_score":0.006269531,"about_ca_system_score_codex":0.00035371247,"about_ca_system_score_gemma":0.00027840736,"threshold_uncertainty_score":0.020973742},"labels":[],"label_agreement":null},{"id":"W4205302416","doi":"10.1093/brain/awab333","title":"Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia","year":2021,"lang":"en","type":"article","venue":"Brain","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Fondazione Regionale per la Ricerca Biomedica; Regione Lombardia; Ministero della Salute; E-Rare","keywords":"Amyotrophic lateral sclerosis; Frontotemporal dementia; C9orf72; Neurodegeneration; Neuroscience; Biology; Cell biology; Dementia; Medicine; Pathology; Disease","score_opus":0.025641394439559588,"score_gpt":0.26430170482234927,"score_spread":0.23866031038278968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4205302416","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99601495,0.0019564508,0.00059307157,0.0001807441,0.000027971524,0.00001948049,0.0003597664,0.00007434224,0.00077318226],"genre_scores_gemma":[0.9972703,0.00085525075,0.0004972076,0.000093658855,0.000015022863,0.000023753886,0.00031056476,0.000010112272,0.000924055],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993026,0.000011673472,0.000010686507,0.000020182706,0.000016484666,0.000010703275],"domain_scores_gemma":[0.99992037,0.000010557399,0.000026591793,0.000005744142,0.0000061665214,0.000030580624],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000086383996,0.0005449657,0.00020140204,0.0005158514,0.0002488552,0.00016878193,0.00014111582,0.00046094166,0.0010829597],"category_scores_gemma":[0.00009275389,0.00013965632,0.00026264167,0.0002205885,0.00035042237,0.00013382442,0.00023509009,0.0003289174,0.0002602688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000384799,0.000092767346,0.0023028634,0.000054030013,0.000028417968,0.0024530233,0.000027344438,0.000059629394,0.9928993,0.00014457817,0.00010773604,0.0014455314],"study_design_scores_gemma":[0.0002535264,0.0012887793,0.26854166,0.000049860028,0.00036020277,0.039492574,0.0002058945,0.0035927498,0.6767179,0.0008653404,0.008593059,0.00003839643],"about_ca_topic_score_codex":0.00088733644,"about_ca_topic_score_gemma":0.0009461683,"teacher_disagreement_score":0.0010829597,"about_ca_system_score_codex":0.0003046531,"about_ca_system_score_gemma":0.00016921993,"threshold_uncertainty_score":0.00362283},"labels":[],"label_agreement":null},{"id":"W4206048897","doi":"","title":"Hepatitis C virus exploits cyclophilin A to evade PKR","year":2020,"lang":"en","type":"article","venue":"UCL Discovery (University College London)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Faculty of Health Sciences, Queen's University; Deutsche Forschungsgemeinschaft; National Institute for Health and Care Research; Canadian Institutes of Health Research; European Commission; Wellcome","keywords":"Protein kinase R; Viral replication; Biology; Cypa; Virology; Innate immune system; Hepatitis C virus; NS5A; Interferon; Cyclophilin A; Interferon regulatory factors; Vesicular stomatitis virus; Virus; Host factor; Antiviral protein; Effector; Viral entry; Cell biology; Hepacivirus; Immune system; Protein kinase A; Kinase; Immunology; Genetics; RNA; Gene","score_opus":0.012425409461014546,"score_gpt":0.20173903968174875,"score_spread":0.1893136302207342,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206048897","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9796153,0.0041682785,0.004942658,0.00070158916,0.00007342031,0.000025408177,0.00019823447,0.0001637105,0.010111458],"genre_scores_gemma":[0.9960951,0.00087445823,0.0011010483,0.0000981245,0.000014783407,0.0000066239754,0.00009031639,0.000007094421,0.0017125724],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992704,0.000018085033,0.0000042498123,0.000012062564,0.000019546991,0.000018969911],"domain_scores_gemma":[0.9999647,0.0000057430875,0.000009743018,0.000005213426,0.0000031829122,0.000011333194],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010907826,0.00018188749,0.00010421075,0.0001436367,0.00015304945,0.0003120081,0.00008815702,0.00018759035,0.00090932625],"category_scores_gemma":[0.00006466635,0.00006916403,0.00012074125,0.000081482016,0.00020429838,0.00013608176,0.00022240575,0.00027546895,0.0003470418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000065108834,0.000011909944,0.00028196722,0.00002040282,0.0000040358946,0.00005802265,0.0000047123676,0.00009384573,0.9959777,0.00044751633,0.00012558736,0.0029092866],"study_design_scores_gemma":[0.000024662946,0.00036341822,0.0076984083,0.000011332493,0.000013211111,0.00081955217,0.0000307712,0.003023983,0.9770866,0.0003355637,0.010583882,0.0000085795255],"about_ca_topic_score_codex":0.00041931323,"about_ca_topic_score_gemma":0.00082598836,"teacher_disagreement_score":0.00090932625,"about_ca_system_score_codex":0.0002890509,"about_ca_system_score_gemma":0.0001828538,"threshold_uncertainty_score":0.0030419827},"labels":[],"label_agreement":null},{"id":"W4206273216","doi":"10.1007/978-1-4419-0461-4_581","title":"Pin1","year":2012,"lang":"en","type":"book-chapter","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"PIN1; Biology; Genetics","score_opus":0.01872308867002919,"score_gpt":0.2342434331285951,"score_spread":0.2155203444585659,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4206273216","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.008053124,0.032703776,0.042158872,0.0023065922,0.003436968,0.00020175893,0.0058275033,0.0045628124,0.9007486],"genre_scores_gemma":[0.02769637,0.0136351045,0.0112916855,0.0012597494,0.0002532942,0.0002014033,0.007576806,0.0006000676,0.9374856],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997652,0.000009482874,0.00000617551,0.00008086127,0.000101612706,0.000036545847],"domain_scores_gemma":[0.9999584,0.0000054341976,0.00000442322,0.000006959943,0.0000111171,0.0000136629005],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020541623,0.0012267336,0.0005183902,0.00085314526,0.0007853115,0.0016818767,0.0010093162,0.00079305476,0.105248764],"category_scores_gemma":[0.00022779882,0.00048796102,0.00044775225,0.00080166594,0.00039882358,0.0012897446,0.0013464425,0.0018872503,0.09387328],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021308177,0.00007886139,0.0002748007,0.0008923116,0.000026748665,0.0004488879,0.000116638425,0.00063640863,0.20374407,0.06428625,0.253369,0.475913],"study_design_scores_gemma":[0.000004783661,0.000023340697,0.00032150274,0.000046237023,0.000007910034,0.0006961464,0.000021212038,0.00017792663,0.024304194,0.0036213514,0.97076225,0.000013098003],"about_ca_topic_score_codex":0.00056076795,"about_ca_topic_score_gemma":0.0010431196,"teacher_disagreement_score":0.89475125,"about_ca_system_score_codex":0.000596778,"about_ca_system_score_gemma":0.00039010632,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W4210309754","doi":"10.1101/2022.01.30.22269378","title":"Human germline biallelic complete NFAT1 deficiency causes the triad of progressive joint contractures, osteochondromas, and susceptibility to B cell malignancy","year":2022,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pacific Centre for Reproductive Medicine; Genome British Columbia; BC Children's Hospital; University of British Columbia","funders":"Canadian Institutes of Health Research; Killam Trusts; Genome British Columbia; BC Children's Hospital; Children's Hospital Foundation","keywords":"Calcineurin; Germline; NFAT; Cancer research; Biology; Transcription factor; Cell biology; Gene; Medicine; Genetics; Internal medicine; Transplantation","score_opus":0.03535122022896375,"score_gpt":0.29320366258498376,"score_spread":0.25785244235602,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210309754","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9778382,0.003240271,0.0059840316,0.00091343274,0.000099427925,0.000024962765,0.0026793017,0.00055041467,0.008669921],"genre_scores_gemma":[0.98508584,0.0009226204,0.0028616495,0.00010810333,0.000045014436,0.000010062938,0.001510438,0.00006607475,0.009390216],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999126,0.000010011695,0.0000052668042,0.00002272268,0.000036274225,0.000013146653],"domain_scores_gemma":[0.99995804,0.000009704997,0.000010400231,0.00000554697,0.000003206986,0.000013069319],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000096018965,0.0003675589,0.00017046287,0.0003839471,0.00017533901,0.0002082652,0.00012449015,0.00040187791,0.004110142],"category_scores_gemma":[0.00011491705,0.00011435877,0.00011169824,0.00020926504,0.00024289009,0.000098344804,0.00026266646,0.00031250916,0.0010830944],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00054701365,0.000086383145,0.013476389,0.00012899585,0.00005923368,0.01297846,0.00013636972,0.000405685,0.94660234,0.0015969214,0.0042014997,0.019780599],"study_design_scores_gemma":[0.000117808406,0.00028643582,0.09096223,0.000049216043,0.00007579497,0.11072128,0.00024622833,0.0034763936,0.7240034,0.0030894428,0.06695053,0.000021221362],"about_ca_topic_score_codex":0.0004564251,"about_ca_topic_score_gemma":0.00055457,"teacher_disagreement_score":0.004110142,"about_ca_system_score_codex":0.00015604126,"about_ca_system_score_gemma":0.00009341768,"threshold_uncertainty_score":0.013749719},"labels":[],"label_agreement":null},{"id":"W4210465864","doi":"10.1016/j.ceca.2022.102545","title":"S-Palmitoylation of calcineurin β1 connects cellular Ca2+ homeostasis to phosphatidylinositol 4-kinase activity at the plasma membrane","year":2022,"lang":"en","type":"letter","venue":"Cell Calcium","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Cancer Research Society","keywords":"Palmitoylation; Dephosphorylation; Calcineurin; Phosphatidylinositol; Cell biology; Chemistry; Kinase; Membrane; Homeostasis; Biochemistry; Phosphorylation; Biology; Phosphatase; Enzyme; Cysteine; Internal medicine","score_opus":0.019282389039980235,"score_gpt":0.24493884338842722,"score_spread":0.225656454348447,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210465864","genre_codex":"commentary","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0033647553,0.0020135145,0.00040713736,0.9354998,0.053222667,0.000023184051,0.000103746876,0.00005937557,0.005305906],"genre_scores_gemma":[0.054078676,0.005142915,0.00087671186,0.7903399,0.10332566,0.00012197078,0.00012989035,0.0000562056,0.045928072],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99935204,0.000191119,0.00006843488,0.000078420126,0.00019934734,0.00011076447],"domain_scores_gemma":[0.99854785,0.0008776654,0.00009935834,0.00006872054,0.00023499543,0.000171416],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0012654057,0.0005883126,0.0005714845,0.00032347566,0.0015365339,0.0016353256,0.0006435163,0.015828164,0.0037582528],"category_scores_gemma":[0.007708694,0.0003226865,0.0007342422,0.00021441006,0.0013762317,0.001002067,0.0005162585,0.010906236,0.0027208494],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0010236413,0.00017776518,0.001257809,0.00012835157,0.00007193447,0.012146921,0.0001487956,0.0003399407,0.0034854324,0.0077681635,0.94802773,0.025423503],"study_design_scores_gemma":[0.0009156948,0.00038054198,0.0044328743,0.00019453987,0.00010706905,0.006926812,0.00039042693,0.0027160565,0.0060505983,0.027838575,0.9499554,0.00009128636],"about_ca_topic_score_codex":0.002764334,"about_ca_topic_score_gemma":0.0032634235,"teacher_disagreement_score":0.015828164,"about_ca_system_score_codex":0.0029817657,"about_ca_system_score_gemma":0.001212682,"threshold_uncertainty_score":0.02163434},"labels":[],"label_agreement":null},{"id":"W4210968093","doi":"10.1021/cr010166y","title":"Signal Peptidases","year":2002,"lang":"en","type":"review","venue":"Chemical Reviews","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":442,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of British Columbia","funders":"National Institute of General Medical Sciences","keywords":"Chemistry; SIGNAL (programming language)","score_opus":0.09751445140912125,"score_gpt":0.3546911763152383,"score_spread":0.25717672490611704,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4210968093","genre_codex":"other","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.020293113,0.056243006,0.016434906,0.0078077074,0.022857022,0.0012344236,0.1478578,0.0091833975,0.7180886],"genre_scores_gemma":[0.0347223,0.022294512,0.007460243,0.0023013542,0.0014191171,0.00042481386,0.14544219,0.00091324426,0.7850223],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.999361,0.00005185802,0.000057218396,0.00011854536,0.00027687047,0.00013462664],"domain_scores_gemma":[0.9995579,0.00005068692,0.00004561255,0.00006112278,0.00013861599,0.00014599063],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00040295496,0.0022818097,0.0008914804,0.0015560767,0.0008439264,0.0027562394,0.0009535608,0.0015440191,0.3896319],"category_scores_gemma":[0.0011729292,0.00055134634,0.0009899782,0.0015637893,0.00025041276,0.0014342094,0.0016450031,0.002106125,0.47077775],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007878904,0.0002807601,0.0008245768,0.0020796142,0.00007287459,0.0006489479,0.00009250418,0.00017479504,0.117032684,0.007572117,0.6333013,0.23713194],"study_design_scores_gemma":[0.000050866267,0.0001166926,0.0013056309,0.00010325484,0.000017648588,0.00045620953,0.000040759816,0.000095769276,0.019706966,0.0009862729,0.9771006,0.000019224583],"about_ca_topic_score_codex":0.00086131704,"about_ca_topic_score_gemma":0.0011004641,"teacher_disagreement_score":0.3896319,"about_ca_system_score_codex":0.0008376038,"about_ca_system_score_gemma":0.00091059343,"threshold_uncertainty_score":0.870616},"labels":[],"label_agreement":null},{"id":"W4212976776","doi":"10.3389/fmicb.2022.828078","title":"Emerging Roles of Cyclophilin A in Regulating Viral Cloaking","year":2022,"lang":"en","type":"review","venue":"Frontiers in Microbiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Faculty of Health Sciences, Queen's University; Queen's University; Natural Sciences and Engineering Research Council of Canada; Mitacs; Canada Foundation for Innovation; Banting Research Foundation","keywords":"Cypa; Innate immune system; Biology; Viral replication; Cyclophilin A; Viral entry; Virology; Virus; Immune system; Cell biology; Immunology","score_opus":0.014797664067140281,"score_gpt":0.2816428493330245,"score_spread":0.26684518526588424,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4212976776","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025072083,0.9981742,0.00018411355,0.00018583208,0.00013844192,0.0000026812493,0.000015712805,0.000008336743,0.0010399272],"genre_scores_gemma":[0.0011605563,0.997761,0.00018752886,0.00013610825,0.000115917916,0.0000052896735,0.000028104407,0.0000014531267,0.000603958],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999311,0.000011062079,0.000009531326,0.000015258085,0.000022566252,0.000010514678],"domain_scores_gemma":[0.99990726,0.000035904122,0.00001313727,0.000003174817,0.000023800572,0.000016697124],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028097822,0.00062276714,0.0006412156,0.0012168753,0.00021704492,0.00078164454,0.00047312403,0.00082714815,0.0019586307],"category_scores_gemma":[0.00024397144,0.00021930881,0.0002968385,0.0012190284,0.00034254955,0.0010003281,0.0005150631,0.0013070387,0.0013681542],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011366882,0.00006497614,0.00022607124,0.0114590945,0.00007325627,0.00030022295,0.00005743429,0.0005605746,0.01018588,0.006935381,0.021416135,0.94860727],"study_design_scores_gemma":[0.000019889996,0.000107894295,0.0010887355,0.0012257588,0.00008779008,0.0011507067,0.00004533524,0.00019285227,0.0021971553,0.002804673,0.9910575,0.000021680222],"about_ca_topic_score_codex":0.00052371155,"about_ca_topic_score_gemma":0.0009908387,"teacher_disagreement_score":0.0019586307,"about_ca_system_score_codex":0.00045974174,"about_ca_system_score_gemma":0.00064369204,"threshold_uncertainty_score":0.006552279},"labels":[],"label_agreement":null},{"id":"W4213055357","doi":"10.1038/s41388-022-02223-y","title":"TSPAN6 is a suppressor of Ras-driven cancer","year":2022,"lang":"en","type":"article","venue":"Oncogene","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"National Health and Medical Research Council; Medical Research Council; La Trobe University; Cancer Council Victoria; Invest Northern Ireland","keywords":"Biology; Suppressor; Carcinogenesis; Cancer; Cancer research; Tumor suppressor gene; Genetics","score_opus":0.01660922445908601,"score_gpt":0.28705734612138384,"score_spread":0.2704481216622978,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4213055357","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9920407,0.0013411834,0.0030409999,0.00015218783,0.000042589967,0.00001574591,0.0012126351,0.0001657184,0.0019883213],"genre_scores_gemma":[0.9913373,0.00052582653,0.0013752036,0.00004397761,0.000010410115,0.000010437024,0.0015489415,0.000019150362,0.0051287385],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999229,0.000012560243,0.0000057935,0.000014590215,0.000034248136,0.000009964922],"domain_scores_gemma":[0.99992347,0.000007481166,0.000022849792,0.0000062128433,0.0000074598993,0.00003241434],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006518133,0.00029268363,0.000114942144,0.0002753224,0.00016461732,0.0001321948,0.00013824196,0.00017155682,0.0021570218],"category_scores_gemma":[0.00007276817,0.00008067162,0.00014998706,0.00014201552,0.00015993466,0.000061130275,0.00016961571,0.00032157847,0.0005887224],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007002449,0.000012413664,0.0006047241,0.000024111172,0.000008598284,0.00030676785,0.0000048807387,0.00008822562,0.9970016,0.00019813488,0.00013009142,0.0015503932],"study_design_scores_gemma":[0.000030776526,0.00024999236,0.023018615,0.000008035239,0.00003751153,0.008506969,0.000029408311,0.003155033,0.9471409,0.00028309587,0.017531399,0.000008157014],"about_ca_topic_score_codex":0.00042841546,"about_ca_topic_score_gemma":0.000738991,"teacher_disagreement_score":0.0021570218,"about_ca_system_score_codex":0.00021654466,"about_ca_system_score_gemma":0.0001434139,"threshold_uncertainty_score":0.0072159767},"labels":[],"label_agreement":null},{"id":"W4220758097","doi":"10.1139/cjc-2021-0359","title":"Allosteric regulation of cyclic nucleotide-dependent protein kinases","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Allosteric regulation; Chemistry; Effector; Allosteric enzyme; Kinase; Small molecule; Computational biology; Biochemistry; Enzyme; Biology","score_opus":0.00835412518148884,"score_gpt":0.20374429984357798,"score_spread":0.19539017466208913,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220758097","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.09751655,0.8212607,0.041440737,0.005581813,0.0021048554,0.00007882259,0.00014338932,0.00044267697,0.03143052],"genre_scores_gemma":[0.45519555,0.5179037,0.011905156,0.0021567568,0.0013576323,0.000065700886,0.00012888463,0.00006961602,0.011217099],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998623,0.00002826126,0.000008176399,0.000026596337,0.000052246553,0.000022382097],"domain_scores_gemma":[0.99993205,0.000033440152,0.000011755202,0.0000037756001,0.000011273903,0.0000075761186],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031276816,0.00029823894,0.00026791645,0.00019879096,0.00024114473,0.00049305835,0.0002885341,0.00034925775,0.00083784293],"category_scores_gemma":[0.0002418615,0.00010654432,0.00018226283,0.00017051862,0.0005262769,0.00040855652,0.00032083248,0.00070198474,0.0003405748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013481629,0.00006475555,0.00043548306,0.002096018,0.000042339532,0.00041679025,0.00023757768,0.002452325,0.7559683,0.04819845,0.007526088,0.1824271],"study_design_scores_gemma":[0.00003250905,0.00034328364,0.0018916775,0.00024739993,0.000066539564,0.0015724925,0.00017326367,0.0063968385,0.45597827,0.018764209,0.51447916,0.000054368014],"about_ca_topic_score_codex":0.00041057175,"about_ca_topic_score_gemma":0.0009461566,"teacher_disagreement_score":0.00083784293,"about_ca_system_score_codex":0.00050130254,"about_ca_system_score_gemma":0.0002558405,"threshold_uncertainty_score":0.0036372542},"labels":[],"label_agreement":null},{"id":"W4220971431","doi":"10.1007/s00018-022-04201-9","title":"CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth","year":2022,"lang":"en","type":"article","venue":"Cellular and Molecular Life Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Children's Hospital Research Institute of Manitoba; University of Manitoba; St. Boniface Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Research Manitoba","keywords":"Endocrinology; Internal medicine; Autocrine signalling; Insulin-like growth factor; Biology; Paracrine signalling; Endogeny; Receptor; Growth factor; Medicine","score_opus":0.02592496982998117,"score_gpt":0.23541249450253537,"score_spread":0.20948752467255422,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4220971431","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9876001,0.0022488218,0.0044169277,0.00021770163,0.0001927424,0.000052037893,0.0017819087,0.00018759217,0.0033022172],"genre_scores_gemma":[0.9851193,0.001499812,0.0027292646,0.00015112471,0.00001911063,0.00012399247,0.0016095759,0.0001231521,0.008624626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998634,0.000005938029,0.00001180641,0.00004110786,0.0000319595,0.00004585699],"domain_scores_gemma":[0.9999218,0.0000067437218,0.000019110827,0.000007962751,0.000013316086,0.00003105486],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009332687,0.00035376524,0.0003175427,0.00020238958,0.0001999229,0.00040355077,0.0002904523,0.00021304595,0.002069672],"category_scores_gemma":[0.000076982156,0.00014270945,0.0002695804,0.00016831186,0.00026860138,0.00018358212,0.000310258,0.0007974223,0.0006628639],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100369536,0.000017054206,0.000047259982,0.000032689954,0.0000023308278,0.000012186428,0.000008509234,0.000015052667,0.99896574,0.000039016173,0.000045385033,0.0007143422],"study_design_scores_gemma":[0.000027086136,0.000119811026,0.0044155195,0.000013362145,0.000015394453,0.00005263921,0.000046021232,0.00040864092,0.9909117,0.000049759867,0.003934969,0.000005137299],"about_ca_topic_score_codex":0.0022113104,"about_ca_topic_score_gemma":0.0030819601,"teacher_disagreement_score":0.0022113104,"about_ca_system_score_codex":0.00047516558,"about_ca_system_score_gemma":0.00041326843,"threshold_uncertainty_score":0.0069237947},"labels":[],"label_agreement":null},{"id":"W4224437039","doi":"10.1038/s41392-022-00972-6","title":"Signaling cascades in the failing heart and emerging therapeutic strategies","year":2022,"lang":"en","type":"review","venue":"Signal Transduction and Targeted Therapy","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Basic and Applied Basic Research Foundation of Guangdong Province; Terry Fox Foundation; National Natural Science Foundation of China","keywords":"Heart failure; Medicine; Computational biology; Neuroscience; Bioinformatics; Biology; Internal medicine","score_opus":0.053564812657907704,"score_gpt":0.32480371556967846,"score_spread":0.2712389029117708,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4224437039","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00094563235,0.98844135,0.0022588486,0.0043475777,0.0011649093,0.000013932762,0.000026312706,0.000041859457,0.0027595514],"genre_scores_gemma":[0.00611273,0.9870407,0.0019268956,0.0019029578,0.0013288923,0.000029317325,0.000043796525,0.000007702985,0.001607116],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99982244,0.000043335203,0.000019923673,0.000029897767,0.000050533356,0.00003390401],"domain_scores_gemma":[0.9998281,0.00006280072,0.00002224807,0.000005135207,0.0000559722,0.000025651809],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006994575,0.0006587251,0.00063202454,0.0010694936,0.00033785764,0.0010524377,0.0005815771,0.0010893584,0.0016779372],"category_scores_gemma":[0.00041728077,0.000161796,0.00042033993,0.00045389924,0.00067206356,0.0014702113,0.00062614103,0.0028332516,0.0008566975],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026853295,0.0002784082,0.0007524886,0.009771155,0.00013159604,0.0011253664,0.0003991784,0.0012197118,0.029415283,0.074105084,0.059552204,0.82298106],"study_design_scores_gemma":[0.00004263501,0.00033872333,0.00079047825,0.0017658673,0.00012522895,0.0022481657,0.0002214939,0.0008414705,0.0060080695,0.018760921,0.9688118,0.000045233537],"about_ca_topic_score_codex":0.00042175115,"about_ca_topic_score_gemma":0.0008255899,"teacher_disagreement_score":0.0016779372,"about_ca_system_score_codex":0.00073024334,"about_ca_system_score_gemma":0.00083099795,"threshold_uncertainty_score":0.005613208},"labels":[],"label_agreement":null},{"id":"W4225402655","doi":"10.1096/fasebj.2022.36.s1.r6277","title":"Palmitoylation Targets the Calcineurin Phosphatase to the Phosphatidylinositol 4‐kinase Complex at the Plasma Membrane","year":2022,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of British Columbia; Lunenfeld-Tanenbaum Research Institute; University of Victoria","funders":"","keywords":"Palmitoylation; Cell biology; Phosphatase; Phosphatidylinositol; Biochemistry; Biology; Gene isoform; Phosphatidylinositol 4,5-bisphosphate; Kinase; Serine; Signal transduction; Phosphorylation; Chemistry; Enzyme; Cysteine; Gene","score_opus":0.018688617426522936,"score_gpt":0.25195988779291084,"score_spread":0.2332712703663879,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4225402655","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9858333,0.0046238503,0.00605418,0.00034584536,0.00006565135,0.000024707248,0.0002130409,0.000078077945,0.0027612075],"genre_scores_gemma":[0.9907175,0.0025822367,0.002274697,0.00010899169,0.000019096184,0.000017784381,0.00039191212,0.000019153289,0.0038685212],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998715,0.00001663662,0.000007968731,0.000032748598,0.000034873367,0.000036227997],"domain_scores_gemma":[0.9999349,0.000008457528,0.00002006395,0.000008511141,0.000009377822,0.00001870858],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012733156,0.00028896326,0.00013107953,0.00011918384,0.0002653317,0.00039897434,0.00020820266,0.00024252656,0.0011199452],"category_scores_gemma":[0.00012701978,0.00015228012,0.00021168726,0.00010304698,0.00024277248,0.0002308265,0.00029220045,0.00056565297,0.00046236327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000075355056,0.000008101824,0.0002354694,0.000032497053,0.000004353933,0.000057869256,0.000012175417,0.00006580211,0.9981135,0.00032003716,0.000037175178,0.0010375703],"study_design_scores_gemma":[0.000012542682,0.00004984329,0.005958368,0.000007208986,0.000012510738,0.00032197317,0.00002593623,0.0013390451,0.98669785,0.00019445995,0.005376231,0.0000039830406],"about_ca_topic_score_codex":0.0011917226,"about_ca_topic_score_gemma":0.0019497697,"teacher_disagreement_score":0.0011917226,"about_ca_system_score_codex":0.00063745,"about_ca_system_score_gemma":0.00038816713,"threshold_uncertainty_score":0.004625082},"labels":[],"label_agreement":null},{"id":"W4229458948","doi":"10.21203/rs.3.rs-1499067/v1","title":"Towards In Vivo Proof-of-Binding of 18F-labeled Inhibitor [18F]TRACK to Peripheral Tropomyosin Receptor Kinases","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta; McGill University; University Health Network","funders":"University of Alberta; Weston Brain Institute; Canadian Institutes of Health Research; Cancer Research Society","keywords":"In vivo; Kinase; Tropomyosin; Chemistry; Receptor; Cell biology; Molecular biology; Biochemistry; Actin; Biology; Genetics","score_opus":0.04881611705210007,"score_gpt":0.38194536843350646,"score_spread":0.33312925138140637,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229458948","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87937254,0.0064367005,0.10336547,0.00031023595,0.00013584051,0.00047649076,0.002039668,0.0005592353,0.007303872],"genre_scores_gemma":[0.9110069,0.0039932556,0.07056763,0.00017470332,0.000056240053,0.00048499875,0.0026932957,0.00019675175,0.010826224],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99961996,0.000106861815,0.000019635982,0.0001254682,0.00006369374,0.000064234446],"domain_scores_gemma":[0.9997298,0.00009685849,0.000054688164,0.000043570697,0.00004544518,0.000029632945],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006991922,0.00081554474,0.00062835356,0.00021650028,0.0002613044,0.0004759432,0.0008371849,0.0007178775,0.0026183932],"category_scores_gemma":[0.0004166196,0.00044536064,0.00040882768,0.0002486676,0.00023207995,0.00033421902,0.00023951575,0.00076667004,0.001211772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017526455,0.00004282392,0.00007785628,0.00009329256,0.0000083681525,0.000057252513,0.000020605617,0.0001953223,0.99795437,0.00013628595,0.000121892575,0.0011167224],"study_design_scores_gemma":[0.000030215107,0.00037743448,0.00041297302,0.000009571297,0.000017540626,0.0003352783,0.000012379046,0.0014892232,0.9939719,0.000021835616,0.0033146976,0.000006963147],"about_ca_topic_score_codex":0.0014218924,"about_ca_topic_score_gemma":0.0015273709,"teacher_disagreement_score":0.0026183932,"about_ca_system_score_codex":0.0004965762,"about_ca_system_score_gemma":0.00039113278,"threshold_uncertainty_score":0.008759439},"labels":[],"label_agreement":null},{"id":"W4229987485","doi":"10.1139/y01-031","title":"Mechanical load-induced alterations in B-type natriuretic peptide gene expression","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Medical Research Council; Academy of Finland; Finska Läkaresällskapet; Aarne Koskelon Säätiö","keywords":"Natriuretic peptide; Internal medicine; Brain natriuretic peptide; NPR2; Paracrine signalling; Autocrine signalling; Atrial natriuretic peptide; Endocrinology; Volume overload; Heart failure; Gene expression; Angiotensin II; Medicine; Biology; Gene; Receptor","score_opus":0.019183617410113415,"score_gpt":0.2870657941201646,"score_spread":0.26788217671005116,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4229987485","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99218315,0.0032744037,0.0013663044,0.00011875724,0.000055799967,0.00003460977,0.00050458516,0.000057151123,0.0024051396],"genre_scores_gemma":[0.99270016,0.0022597676,0.0007881064,0.00009038791,0.000025990936,0.00007178956,0.00043627844,0.000011371222,0.0036162562],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988806,0.000011151826,0.0000050934614,0.00002456128,0.000039316583,0.00003169246],"domain_scores_gemma":[0.99992585,0.000017008457,0.000018457364,0.000006216331,0.000010023818,0.00002243481],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007687666,0.00018134752,0.00018045558,0.00027796841,0.0001300301,0.00013243072,0.0001266399,0.00019311592,0.0017757735],"category_scores_gemma":[0.00009337636,0.00007959419,0.00012815841,0.00020198629,0.00030044158,0.00012899458,0.00014486059,0.00030827604,0.00015800384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010915152,0.000031014486,0.0003753725,0.000034005752,0.0000026546581,0.000105769075,0.00003156126,0.000021801885,0.99680907,0.00007160912,0.000038187525,0.0023697328],"study_design_scores_gemma":[0.000047680383,0.0025344328,0.2920385,0.000025331601,0.000031870364,0.0011620373,0.00030595725,0.0007054144,0.6986255,0.00041589534,0.0040800837,0.000027283315],"about_ca_topic_score_codex":0.0014330196,"about_ca_topic_score_gemma":0.00168276,"teacher_disagreement_score":0.0017757735,"about_ca_system_score_codex":0.00036077228,"about_ca_system_score_gemma":0.00019693379,"threshold_uncertainty_score":0.0059405565},"labels":[],"label_agreement":null},{"id":"W4231919180","doi":"10.1080/13543776.2017.1297797","title":"Tropomyosin receptor kinase inhibitors: an updated patent review for 2010-2016 – <i>Part II</i>","year":2017,"lang":"en","type":"review","venue":"Expert Opinion on Therapeutic Patents","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Trk receptor; Tropomyosin receptor kinase A; Drug development; Medicine; Pharmacology; Cancer research; Internal medicine; Drug; Receptor; Neurotrophin","score_opus":0.22703980821993844,"score_gpt":0.40521853145020315,"score_spread":0.1781787232302647,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4231919180","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00061387726,0.9865173,0.0004471196,0.0015954212,0.0012987206,0.00005051338,0.00039174326,0.00004912041,0.009036187],"genre_scores_gemma":[0.0021923506,0.9911724,0.00043912252,0.0009423847,0.00046720775,0.000028841343,0.00041853817,0.000007060505,0.004332162],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99982315,0.000019757255,0.00002291567,0.00003040089,0.00007586525,0.000027895188],"domain_scores_gemma":[0.9997967,0.000059506176,0.000051721214,0.0000052832565,0.00006627412,0.000020601216],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00038427868,0.00074711785,0.00089474686,0.0020608853,0.00024736114,0.0010249644,0.00073064957,0.00079656823,0.014345719],"category_scores_gemma":[0.0006686667,0.00023093435,0.00073451165,0.0019595695,0.00024699798,0.0013518713,0.0005153315,0.0014548219,0.0053804554],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010037288,0.00006483311,0.000083172374,0.017911192,0.000073348,0.0003053169,0.000057040135,0.00028503154,0.0037783422,0.003914504,0.11019164,0.8632352],"study_design_scores_gemma":[0.000018939034,0.00007837294,0.0003180592,0.002058897,0.00008536935,0.0007046966,0.000020288408,0.00005500522,0.0004934957,0.0006926061,0.9954625,0.000011714694],"about_ca_topic_score_codex":0.0008883042,"about_ca_topic_score_gemma":0.002408788,"teacher_disagreement_score":0.014345719,"about_ca_system_score_codex":0.0006828929,"about_ca_system_score_gemma":0.001248154,"threshold_uncertainty_score":0.047991157},"labels":[],"label_agreement":null},{"id":"W4233390212","doi":"10.1128/mcb.20.5.1898-1898.2000","title":"Cak1 Is Required for Kin28 Phosphorylation and Activation In Vivo","year":2000,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; Natural Sciences and Engineering Research Council of Canada; Damon Runyon Cancer Research Foundation","keywords":"Biology; Phosphorylation; In vivo; Cell biology; Computational biology; Molecular biology; Genetics","score_opus":0.008819110338106064,"score_gpt":0.23792308080891145,"score_spread":0.22910397047080538,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4233390212","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99465454,0.0014103816,0.0018712062,0.00011150644,0.00002094938,0.000013994786,0.0005567009,0.00010440234,0.0012562145],"genre_scores_gemma":[0.99494725,0.00036037774,0.0012414554,0.00003213982,0.000005292286,0.000021244703,0.0014355686,0.000055603425,0.001901085],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985075,0.000015822076,0.000014357227,0.00004082737,0.000040306793,0.000038027036],"domain_scores_gemma":[0.999668,0.000059946644,0.00009764276,0.00004395245,0.000025924599,0.00010454272],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012568172,0.00051458686,0.0002880572,0.00021289993,0.00025736788,0.00046810802,0.00038796215,0.00027375272,0.0016036747],"category_scores_gemma":[0.00023754172,0.00024503283,0.0001917797,0.00013178147,0.00026125408,0.00025277724,0.00041957208,0.0006005833,0.0009818111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008047409,0.000014450958,0.00022079496,0.00002044117,0.000002277881,0.000054594744,0.000008516923,0.00005307621,0.99902093,0.00007253697,0.00003205281,0.00041983838],"study_design_scores_gemma":[0.00002313249,0.000051462972,0.010337156,0.0000063946213,0.000010036444,0.0005427107,0.000030668987,0.001005667,0.9856324,0.00007523415,0.0022761708,0.000008910523],"about_ca_topic_score_codex":0.0018601057,"about_ca_topic_score_gemma":0.0027131604,"teacher_disagreement_score":0.0018601057,"about_ca_system_score_codex":0.0006789908,"about_ca_system_score_gemma":0.00036039567,"threshold_uncertainty_score":0.0053647757},"labels":[],"label_agreement":null},{"id":"W4236579140","doi":"10.21203/rs.3.rs-91695/v1","title":"NFATc1 Promotes Epithelial-Mesenchymal Transition and Facilitates Colorectal Cancer Metastasis by Targeting SNAI1","year":2020,"lang":"en","type":"preprint","venue":"Research Square","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"Key Science and Technology Program of Shaanxi Province; National Natural Science Foundation of China","keywords":"SNAI1; Epithelial–mesenchymal transition; Colorectal cancer; Metastasis; Cancer research; Breast cancer metastasis; Cancer; Cancer metastasis; Medicine; Internal medicine","score_opus":0.0415012185440376,"score_gpt":0.358258829283053,"score_spread":0.3167576107390154,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4236579140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9425582,0.008811964,0.01984281,0.0026263606,0.0005577077,0.00005231841,0.0034718255,0.0012059312,0.020872891],"genre_scores_gemma":[0.9711889,0.0021252825,0.0053331777,0.00011970069,0.00006578665,0.00002949232,0.0019498856,0.00021249238,0.018975323],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983644,0.000014803526,0.000007875541,0.00003687823,0.000066684166,0.00003730664],"domain_scores_gemma":[0.9999037,0.000015212422,0.000025381,0.000012762295,0.00001415021,0.000028791588],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001570981,0.00038174528,0.00020622987,0.00041064847,0.00025062484,0.00046319174,0.0002395041,0.00035051678,0.006752012],"category_scores_gemma":[0.0002214071,0.0002415847,0.00027014592,0.00031434806,0.00026224932,0.00030768028,0.00026746548,0.0008832722,0.0018565791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025494126,0.00004071644,0.00041829402,0.000073267016,0.000012257525,0.00008256918,0.00001865077,0.00021849641,0.9925081,0.0008904737,0.000773248,0.0047089127],"study_design_scores_gemma":[0.000056236182,0.00008984228,0.0057198233,0.000008815622,0.000021683874,0.00034456034,0.000034676654,0.00302919,0.9792747,0.00068695436,0.0107258605,0.000007663543],"about_ca_topic_score_codex":0.0012029209,"about_ca_topic_score_gemma":0.0016616193,"teacher_disagreement_score":0.006752012,"about_ca_system_score_codex":0.00049134233,"about_ca_system_score_gemma":0.00028807178,"threshold_uncertainty_score":0.022587717},"labels":[],"label_agreement":null},{"id":"W4239266640","doi":"10.1016/s0166-6851(01)00450-9","title":"A Schistosoma mansoni Pad1 homologue stabilizes c-Jun","year":2002,"lang":"en","type":"article","venue":"Molecular and Biochemical Parasitology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Fonds pour la Formation de Chercheurs et l'Aide à la Recherche","keywords":"Schistosoma mansoni; Biology; Molecular biology; Cell biology; Schistosomiasis; Immunology; Helminths","score_opus":0.010392499746855719,"score_gpt":0.24837973996152005,"score_spread":0.23798724021466433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239266640","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99464595,0.0011844164,0.002693066,0.00012955305,0.000049144426,0.000010732016,0.00021536023,0.00009598632,0.00097587425],"genre_scores_gemma":[0.99650276,0.00029088528,0.0008315549,0.000039222054,0.000008707658,0.000009840699,0.0005038337,0.000017586548,0.0017956472],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992764,0.000010433692,0.00000551439,0.00002013511,0.000014882451,0.000021427175],"domain_scores_gemma":[0.9998356,0.00003041629,0.00004798457,0.000026748039,0.000014870782,0.00004425941],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015328327,0.00034284408,0.0001634714,0.00017275166,0.00035104566,0.00028943227,0.00023572055,0.00025750755,0.001952189],"category_scores_gemma":[0.00020571965,0.00017320557,0.00022700657,0.00010186143,0.00025296287,0.00024335185,0.00030569293,0.0006058493,0.00093330676],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00019341534,0.000016568865,0.00018130796,0.00004153405,0.0000041784765,0.00010421554,0.000010961447,0.000059073747,0.9981488,0.00020143551,0.00006703861,0.0009716347],"study_design_scores_gemma":[0.000019576742,0.00008684704,0.004326506,0.0000044471935,0.000008444323,0.00050188706,0.000032392723,0.0009089101,0.99202794,0.00010912659,0.0019696709,0.000004162663],"about_ca_topic_score_codex":0.00017919447,"about_ca_topic_score_gemma":0.00029071854,"teacher_disagreement_score":0.001952189,"about_ca_system_score_codex":0.0003113992,"about_ca_system_score_gemma":0.00014263531,"threshold_uncertainty_score":0.0065307617},"labels":[],"label_agreement":null},{"id":"W4239681234","doi":"10.1155/2012/323462","title":"Corrigendum","year":2012,"lang":"en","type":"erratum","venue":"Canadian Journal of Gastroenterology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Philosophy","score_opus":0.016550125338668134,"score_gpt":0.2265651928635643,"score_spread":0.21001506752489618,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4239681234","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025143343,0.011412668,0.0010770148,0.037992645,0.86235964,0.000077986704,0.001282724,0.00062753574,0.084918365],"genre_scores_gemma":[0.0059626373,0.014168752,0.0018976139,0.024984369,0.113920175,0.00011533877,0.0017801833,0.00057702063,0.8365938],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99853015,0.00017913422,0.00015305223,0.00034115787,0.00068239606,0.00011407779],"domain_scores_gemma":[0.99520606,0.0004955552,0.00018144495,0.00042175996,0.003289863,0.0004053601],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011461071,0.00090637826,0.001002245,0.0017332828,0.0013924935,0.002564731,0.0016278202,0.0020828727,0.22604798],"category_scores_gemma":[0.012556502,0.00034818344,0.000663538,0.0009537912,0.00065182557,0.0012333873,0.0014030382,0.002411988,0.167527],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000013470551,0.0000046141568,0.00004331386,0.00009794256,0.000003575773,0.00011678805,0.000013072102,0.000027478847,0.000058187037,0.0009303952,0.9710608,0.027630297],"study_design_scores_gemma":[0.00000383103,0.0000067557717,0.00015285957,0.00006827833,0.000004637854,0.0002052929,0.000013780341,0.000024328005,0.00009673723,0.00037119543,0.9990477,0.0000045343777],"about_ca_topic_score_codex":0.006834728,"about_ca_topic_score_gemma":0.011586944,"teacher_disagreement_score":0.22604798,"about_ca_system_score_codex":0.0027755138,"about_ca_system_score_gemma":0.0020185038,"threshold_uncertainty_score":0.7562058},"labels":[],"label_agreement":null},{"id":"W4240130997","doi":"10.1055/s-0031-1276479","title":"Involvement of calcineurin in ischemic myocardial damage","year":2005,"lang":"en","type":"article","venue":"International Journal of Angiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency","funders":"","keywords":"Medicine; Calcineurin; Angiology; Cardiology; Internal medicine; Intensive care medicine; Transplantation","score_opus":0.011348495466134154,"score_gpt":0.2828853688960296,"score_spread":0.27153687342989546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240130997","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8608992,0.12823182,0.002187999,0.00067990745,0.00013214225,0.00005558318,0.00007661326,0.000098243145,0.00763847],"genre_scores_gemma":[0.9801769,0.01745775,0.00058621,0.0001306311,0.00014748488,0.00001728904,0.00006110412,0.0000045649854,0.0014180643],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988735,0.000026095908,0.000010057971,0.000015135825,0.00003298501,0.000028365874],"domain_scores_gemma":[0.9998066,0.00003435173,0.000067079796,0.000018142531,0.000024793573,0.00004907419],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035434426,0.0003608151,0.0003266101,0.000598991,0.00027622425,0.00036424198,0.00028024332,0.0005351688,0.00080991874],"category_scores_gemma":[0.00038089883,0.00012612135,0.0001349364,0.00021715545,0.00043135183,0.00034054753,0.00024783943,0.00034905205,0.000107028725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0014518456,0.00025958798,0.0058638807,0.00069118507,0.00008089813,0.0035433844,0.00023118705,0.00034445687,0.9509332,0.0022654207,0.00037356684,0.03396129],"study_design_scores_gemma":[0.00041751494,0.0038476668,0.24402991,0.00033915378,0.00049244025,0.015683481,0.00053274824,0.0042654523,0.6991867,0.0081603965,0.022990033,0.00005465029],"about_ca_topic_score_codex":0.0003709329,"about_ca_topic_score_gemma":0.00042170697,"teacher_disagreement_score":0.00080991874,"about_ca_system_score_codex":0.000402524,"about_ca_system_score_gemma":0.00022787876,"threshold_uncertainty_score":0.0029205084},"labels":[],"label_agreement":null},{"id":"W4242028916","doi":"10.1139/y01-036","title":"Signaling mechanisms underlying strain-dependent brain natriuretic peptide gene transcription","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; American Heart Association","keywords":"Signal transduction; Integrin; Natriuretic peptide; Myocyte; Atrial natriuretic peptide; Biology; Protein kinase A; Reporter gene; Molecular biology; Brain natriuretic peptide; Gene expression; Cell biology; Internal medicine; Endocrinology; Kinase; Gene; Receptor; Medicine; Biochemistry; Heart failure","score_opus":0.024584000389015443,"score_gpt":0.2766711760351063,"score_spread":0.2520871756460909,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242028916","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9722992,0.011548061,0.009872969,0.0006344729,0.00005731025,0.000061101935,0.0006197251,0.000073914314,0.00483325],"genre_scores_gemma":[0.98583764,0.0068910257,0.0030535015,0.000122069476,0.000033498083,0.0000761067,0.00055984413,0.0000069309526,0.0034193615],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998166,0.00002429417,0.000008391126,0.000033934673,0.00006530434,0.00005153863],"domain_scores_gemma":[0.9999218,0.00001351766,0.000024825442,0.0000042409433,0.000013360289,0.000022240016],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010632844,0.00034636835,0.0001406557,0.0001634111,0.00018719638,0.00026967682,0.00016359912,0.00027405354,0.0009909727],"category_scores_gemma":[0.00011622626,0.00013220009,0.00013818569,0.00009025784,0.00025011066,0.00022874233,0.00017149108,0.00054630695,0.00030033046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000039890914,0.000013930622,0.00018101861,0.000023564658,0.0000016345217,0.000053073854,0.000013562083,0.00004605678,0.99803,0.00025096568,0.000024625302,0.0013217321],"study_design_scores_gemma":[0.00004312035,0.0004527466,0.055807676,0.00003055697,0.000021856042,0.0006075545,0.00013583446,0.0024046875,0.9350604,0.0011361566,0.0042805383,0.00001881243],"about_ca_topic_score_codex":0.00080541027,"about_ca_topic_score_gemma":0.001507717,"teacher_disagreement_score":0.0009909727,"about_ca_system_score_codex":0.00050527183,"about_ca_system_score_gemma":0.0002914698,"threshold_uncertainty_score":0.0036659837},"labels":[],"label_agreement":null},{"id":"W4242189890","doi":"10.21037/tcr.2016.09.30","title":"Activation of calcineurin in cancer: many paths, one hub","year":2016,"lang":"en","type":"article","venue":"Translational Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Calcineurin; NFAT; Signal transduction; Cancer research; Biology; Cell biology; Medicine; Internal medicine; Transplantation","score_opus":0.12385343042331223,"score_gpt":0.4211641115804053,"score_spread":0.297310681157093,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242189890","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004848822,0.89030874,0.0034001907,0.088622406,0.005763901,0.000029826891,0.00014695695,0.00016316309,0.0067161284],"genre_scores_gemma":[0.056174934,0.8999012,0.0034896464,0.018959893,0.012402224,0.000061440944,0.0000892228,0.000059158276,0.0088623],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9993192,0.00016655421,0.000056603963,0.00012235707,0.00023813506,0.00009720915],"domain_scores_gemma":[0.9985191,0.00041239275,0.00013187465,0.00012642797,0.00042311515,0.00038703345],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001804419,0.0008974168,0.0011945138,0.0013312395,0.0010779841,0.0040342016,0.00078771816,0.0024056803,0.0036684496],"category_scores_gemma":[0.0011233408,0.00034448795,0.0005822628,0.0010869389,0.003001291,0.005587474,0.00238725,0.004996281,0.0013467618],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013656217,0.0003604841,0.005520169,0.0073431036,0.00043004198,0.002356821,0.0015811236,0.00083698647,0.033843968,0.12835576,0.13682282,0.68118304],"study_design_scores_gemma":[0.00015028054,0.0005842818,0.0056469627,0.0025968524,0.00021413829,0.004415306,0.0015997333,0.00051887194,0.008757042,0.103944235,0.8714326,0.0001398054],"about_ca_topic_score_codex":0.0005892231,"about_ca_topic_score_gemma":0.0011219329,"teacher_disagreement_score":0.0040342016,"about_ca_system_score_codex":0.0014749526,"about_ca_system_score_gemma":0.0019091045,"threshold_uncertainty_score":0.012272239},"labels":[],"label_agreement":null},{"id":"W4242649630","doi":"10.1007/978-3-319-67199-4_581","title":"Pin1","year":2017,"lang":"en","type":"book-chapter","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"PIN1; Physics; Nuclear magnetic resonance","score_opus":0.022250150936857876,"score_gpt":0.2585143657425208,"score_spread":0.23626421480566293,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4242649630","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0050583812,0.032401312,0.03282401,0.0025867978,0.0041323532,0.00015830393,0.004227076,0.0035546361,0.91505706],"genre_scores_gemma":[0.020284664,0.015086896,0.008263737,0.0014286472,0.00033262084,0.000172466,0.0056519904,0.0005925792,0.9481865],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99976474,0.000010404927,0.0000060546527,0.00007839836,0.00010578709,0.000034608383],"domain_scores_gemma":[0.99995244,0.000006803962,0.000004828709,0.0000076043157,0.000013131988,0.000015113732],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022253557,0.001208582,0.00048083437,0.0008449234,0.0007724101,0.0018545284,0.0010028272,0.000801713,0.118637405],"category_scores_gemma":[0.00028513762,0.0004550061,0.0004244919,0.0008113018,0.00043883256,0.0014846914,0.0014735521,0.0020159166,0.09950272],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017119665,0.000066329405,0.0002254149,0.0008540732,0.000020873262,0.00037067718,0.0001195466,0.0006028189,0.111717135,0.082073316,0.31737825,0.4864004],"study_design_scores_gemma":[0.0000036023314,0.000016004537,0.00020304318,0.000049927712,0.000005529469,0.00048805054,0.000019906327,0.00013446034,0.012048327,0.0042050364,0.9828159,0.000010112598],"about_ca_topic_score_codex":0.0005913611,"about_ca_topic_score_gemma":0.0010275856,"teacher_disagreement_score":0.8813626,"about_ca_system_score_codex":0.0006729644,"about_ca_system_score_gemma":0.00044713257,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W4244456576","doi":"10.3410/f.1002762.222575","title":"Faculty Opinions recommendation of A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein.","year":2004,"lang":"en","type":"dataset","venue":"Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Ankyrin; Cell biology; Ankyrin repeat; Signal transduction; Chemistry; Neurotrophin; Biology; Biochemistry; Gene; Receptor","score_opus":0.03521471110975401,"score_gpt":0.35214091293790833,"score_spread":0.31692620182815434,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244456576","genre_codex":"dataset","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004626495,0.00012598878,0.00009478613,0.00010292401,0.000025808811,0.000011783668,0.9979869,0.0003517778,0.00083728513],"genre_scores_gemma":[0.0009391231,0.000085532556,0.00029257307,0.00004261342,0.000005991661,0.000030491756,0.9976215,0.00003816249,0.00094398175],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9989599,0.00014250306,0.000113151415,0.00030386998,0.00033992055,0.00014067639],"domain_scores_gemma":[0.9975197,0.00066607236,0.0003418846,0.00049891573,0.00063875626,0.00033460723],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00082564057,0.0022742385,0.0013014743,0.0035024185,0.0006462787,0.0021751358,0.002280224,0.0021942484,0.039405737],"category_scores_gemma":[0.0053728,0.00055518566,0.0013962215,0.0052455603,0.0002500456,0.0011152374,0.0010040054,0.0014531508,0.039573193],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020765806,0.00004894698,0.002505521,0.00096280157,0.00009847605,0.00005318371,0.000013609803,0.0005019085,0.0004872229,0.00032525355,0.9893091,0.005486378],"study_design_scores_gemma":[0.0005227523,0.000052263487,0.017409064,0.0002694799,0.0001897162,0.00015103874,0.000058349306,0.002203029,0.0025445223,0.0010479767,0.9755023,0.0000494466],"about_ca_topic_score_codex":0.025754008,"about_ca_topic_score_gemma":0.05353106,"teacher_disagreement_score":0.039405737,"about_ca_system_score_codex":0.0012593883,"about_ca_system_score_gemma":0.0031285777,"threshold_uncertainty_score":0.13182533},"labels":[],"label_agreement":null},{"id":"W4244624056","doi":"10.1007/978-1-4614-6438-9_581-1","title":"Pin1","year":2017,"lang":"en","type":"book-chapter","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"","keywords":"PIN1; Biology; Genetics","score_opus":0.022250150936857876,"score_gpt":0.2585143657425208,"score_spread":0.23626421480566293,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4244624056","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0050583812,0.032401312,0.03282401,0.0025867978,0.0041323532,0.00015830393,0.004227076,0.0035546361,0.91505706],"genre_scores_gemma":[0.020284664,0.015086896,0.008263737,0.0014286472,0.00033262084,0.000172466,0.0056519904,0.0005925792,0.9481865],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99976474,0.000010404927,0.0000060546527,0.00007839836,0.00010578709,0.000034608383],"domain_scores_gemma":[0.99995244,0.000006803962,0.000004828709,0.0000076043157,0.000013131988,0.000015113732],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022253557,0.001208582,0.00048083437,0.0008449234,0.0007724101,0.0018545284,0.0010028272,0.000801713,0.118637405],"category_scores_gemma":[0.00028513762,0.0004550061,0.0004244919,0.0008113018,0.00043883256,0.0014846914,0.0014735521,0.0020159166,0.09950272],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017119665,0.000066329405,0.0002254149,0.0008540732,0.000020873262,0.00037067718,0.0001195466,0.0006028189,0.111717135,0.082073316,0.31737825,0.4864004],"study_design_scores_gemma":[0.0000036023314,0.000016004537,0.00020304318,0.000049927712,0.000005529469,0.00048805054,0.000019906327,0.00013446034,0.012048327,0.0042050364,0.9828159,0.000010112598],"about_ca_topic_score_codex":0.0005913611,"about_ca_topic_score_gemma":0.0010275856,"teacher_disagreement_score":0.118637405,"about_ca_system_score_codex":0.0006729644,"about_ca_system_score_gemma":0.00044713257,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W4254528243","doi":"10.1007/978-3-319-67199-4_101792","title":"GRK5","year":2017,"lang":"en","type":"book-chapter","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Computer science","score_opus":0.022108711923801865,"score_gpt":0.25735114038589463,"score_spread":0.23524242846209276,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254528243","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.012068946,0.07578443,0.030097445,0.005652848,0.009246935,0.00015065816,0.0076762345,0.005262578,0.85405993],"genre_scores_gemma":[0.049323913,0.0274028,0.011221879,0.002287705,0.00053919136,0.00013256431,0.008662282,0.000818564,0.8996111],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998006,0.00001104672,0.000007616413,0.00006668445,0.00007749457,0.000036589718],"domain_scores_gemma":[0.9999573,0.0000053704616,0.000004925234,0.000008608811,0.000010602154,0.000013204602],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017712473,0.0011032646,0.0003990854,0.0006540748,0.00051578606,0.0016075071,0.0011367839,0.000780697,0.07448517],"category_scores_gemma":[0.00025282786,0.00028992636,0.0004684859,0.00062220177,0.00041652823,0.0010194392,0.00089723506,0.0019033953,0.079016685],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026412428,0.000063697764,0.00019603103,0.0010496964,0.000036537964,0.0003088737,0.000102769016,0.001032015,0.11050596,0.07443494,0.33009708,0.48190814],"study_design_scores_gemma":[0.000010083834,0.000025561892,0.00022007345,0.00007328841,0.000010245385,0.00040647408,0.000021187005,0.00018524921,0.015398259,0.004559565,0.9790759,0.00001388757],"about_ca_topic_score_codex":0.0009544956,"about_ca_topic_score_gemma":0.0014461303,"teacher_disagreement_score":0.07448517,"about_ca_system_score_codex":0.0009828438,"about_ca_system_score_gemma":0.0005215324,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W4254819702","doi":"10.1007/978-1-4614-6438-9_101792-1","title":"GRK5","year":2016,"lang":"en","type":"book-chapter","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Computer science","score_opus":0.013462128475876274,"score_gpt":0.228024232441758,"score_spread":0.21456210396588174,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4254819702","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.014894988,0.07652738,0.03207903,0.0054100757,0.008705375,0.00016459722,0.008708402,0.0056800074,0.8478302],"genre_scores_gemma":[0.060103957,0.027029997,0.012190679,0.0022324452,0.00049539545,0.00013871922,0.009961121,0.0008341458,0.88701355],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997937,0.000010979279,0.000008369947,0.00007095049,0.00007774957,0.000038368038],"domain_scores_gemma":[0.99995756,0.000004936229,0.000005121156,0.000008782207,0.000010324587,0.00001321515],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017756931,0.0011136767,0.00041426872,0.0006622176,0.00050828734,0.0015653179,0.0011530756,0.00077043887,0.070217535],"category_scores_gemma":[0.00024211277,0.0002946811,0.0004822357,0.0006120798,0.00042057442,0.0009789338,0.0008923103,0.001878302,0.07525063],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031173386,0.000068622016,0.00022927558,0.0011413272,0.000042713265,0.00034619696,0.00011090733,0.0011287852,0.14001893,0.070094705,0.29962623,0.48688066],"study_design_scores_gemma":[0.000012124421,0.000030221529,0.00026812495,0.00007501903,0.000012326363,0.0004730187,0.000022965689,0.00020632449,0.019968418,0.004338114,0.9745774,0.000015905378],"about_ca_topic_score_codex":0.00097348535,"about_ca_topic_score_gemma":0.0014688545,"teacher_disagreement_score":0.070217535,"about_ca_system_score_codex":0.0009513076,"about_ca_system_score_gemma":0.00052097265,"threshold_uncertainty_score":0},"labels":[],"label_agreement":null},{"id":"W4281394602","doi":"10.3389/fphar.2022.795176","title":"Distinct Gene Expression Patterns of Calcium Channels and Related Signaling Pathways Discovered in Lymphomas","year":2022,"lang":"en","type":"article","venue":"Frontiers in Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; Vancouver General Hospital; Spinal Cord Injury BC; University of British Columbia","funders":"Canadian Institutes of Health Research; Urology Foundation","keywords":"Signal transduction; Gene expression; Calcium signaling; Gene; Cell biology; Biology; Cancer research; Computational biology; Neuroscience; Genetics","score_opus":0.012764767028725102,"score_gpt":0.25207094897194704,"score_spread":0.23930618194322195,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4281394602","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9957579,0.0013340355,0.0009628705,0.000028083796,0.000006402189,0.000017905808,0.000978207,0.000038718954,0.00087597227],"genre_scores_gemma":[0.99535817,0.00080401095,0.0009576825,0.00006136962,0.000015061188,0.00004807566,0.0014689045,0.000018037763,0.0012687189],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99980456,0.000013382581,0.00001540922,0.000073194904,0.0000361751,0.000057260822],"domain_scores_gemma":[0.9998485,0.000036538815,0.00004581954,0.000012243044,0.000030544994,0.000026404958],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010228873,0.000118273594,0.00018480096,0.0011112991,0.00014116454,0.00039383888,0.00009742846,0.00018952269,0.0012620311],"category_scores_gemma":[0.0002706143,0.00009857483,0.00017198511,0.0007050289,0.00020369676,0.00014243647,0.00020200614,0.00021266419,0.00034261355],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005266304,0.00003388626,0.052642364,0.00013310261,0.000051738425,0.0006005687,0.00037214629,0.00011773483,0.93050617,0.00020259833,0.00018649676,0.01462667],"study_design_scores_gemma":[0.000045906545,0.00032144735,0.8484011,0.00004089146,0.0001579877,0.0046036453,0.0012250107,0.0012396228,0.13244225,0.00062188046,0.01087303,0.00002717275],"about_ca_topic_score_codex":0.00039001246,"about_ca_topic_score_gemma":0.00059809303,"teacher_disagreement_score":0.0012620311,"about_ca_system_score_codex":0.00016913217,"about_ca_system_score_gemma":0.00009737914,"threshold_uncertainty_score":0.004221916},"labels":[],"label_agreement":null},{"id":"W4283267939","doi":"10.1016/j.celrep.2022.110974","title":"Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus","year":2022,"lang":"en","type":"article","venue":"Cell Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Institut de Recherche Clinique De Montréal; Molson Foundation; National Science Foundation","keywords":"Biology; Immune system; Immunology; Influenza A virus; Virus; Chemokine; Cell biology","score_opus":0.009073402042888862,"score_gpt":0.22075600933940723,"score_spread":0.21168260729651836,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283267939","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99377716,0.0009131803,0.0015652754,0.00020217057,0.000051385305,0.000020539355,0.0003784536,0.00011462927,0.002977167],"genre_scores_gemma":[0.99731904,0.00023087561,0.0003302759,0.000033737684,0.0000075558455,0.000016406299,0.00018825538,0.0000095484775,0.0018643549],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999088,0.00002010104,0.0000075593434,0.000018317398,0.000014631044,0.000030589395],"domain_scores_gemma":[0.9998851,0.0000145358745,0.00003171867,0.000018293325,0.000007424814,0.00004300636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008295265,0.00017196151,0.00012073457,0.00020594652,0.00012649689,0.00022140077,0.000111103465,0.0001801391,0.0019868228],"category_scores_gemma":[0.00009004507,0.000070472204,0.00012224428,0.000067814406,0.00027288916,0.000118871816,0.00018032349,0.00042322418,0.0002805609],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023343746,0.000019584231,0.0005260635,0.000020313231,0.0000036130682,0.00005182606,0.000010413266,0.00003050232,0.9976465,0.00012258405,0.00008058287,0.0012546632],"study_design_scores_gemma":[0.000031115826,0.00034058568,0.019981667,0.0000075072726,0.000012557456,0.00023657287,0.00006621377,0.00068069174,0.9752661,0.000088485765,0.0032837314,0.0000047739427],"about_ca_topic_score_codex":0.0003473503,"about_ca_topic_score_gemma":0.0009775241,"teacher_disagreement_score":0.0019868228,"about_ca_system_score_codex":0.00025822004,"about_ca_system_score_gemma":0.00016092254,"threshold_uncertainty_score":0.006646633},"labels":[],"label_agreement":null},{"id":"W4283832293","doi":"10.1182/blood.2022015674","title":"Human complete NFAT1 deficiency causes a triad of joint contractures, osteochondromas, and B-cell malignancy","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"BC Cancer Agency; BC Children's Hospital; University of British Columbia","funders":"","keywords":"NFAT; Calcineurin; Cancer research; Germline; Biology; CD8; HEK 293 cells; Cell biology; Immunology; Transcription factor; Medicine; Gene; Genetics; Transplantation; Immune system; Internal medicine","score_opus":0.01794821607786281,"score_gpt":0.2319464877928284,"score_spread":0.21399827171496558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4283832293","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.981608,0.008429714,0.0026184598,0.0003622787,0.00003942462,0.00004213733,0.0016654143,0.00027359303,0.0049609826],"genre_scores_gemma":[0.99379265,0.0018953299,0.0015670614,0.000091166825,0.000022873688,0.000010789012,0.0008746258,0.00002733354,0.0017182177],"study_design_codex":"bench_or_experimental","study_design_gemma":"case_report","domain_scores_codex":[0.9998596,0.000015813828,0.000013371247,0.0000548481,0.000037383186,0.000018994337],"domain_scores_gemma":[0.9998841,0.000028172697,0.000033797725,0.000009927004,0.000009877425,0.00003404475],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010284946,0.0006972845,0.00030662463,0.000696375,0.00031972348,0.0002027674,0.00015776597,0.00043531237,0.0027519006],"category_scores_gemma":[0.0002850947,0.00014898843,0.00015477664,0.00034951422,0.00039562874,0.00018416278,0.00032400712,0.00030319794,0.00037988255],"study_design_candidate":"case_report","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013592682,0.0001343711,0.045504067,0.00033860846,0.00011819662,0.04928669,0.0003602276,0.00029136223,0.8531631,0.0007653577,0.001800846,0.04687785],"study_design_scores_gemma":[0.00009527233,0.0009832899,0.22390756,0.000101813115,0.00018211527,0.52923477,0.00029426528,0.0005887254,0.20916697,0.0011061057,0.034298208,0.000040888208],"about_ca_topic_score_codex":0.0007090981,"about_ca_topic_score_gemma":0.00081282156,"teacher_disagreement_score":0.0027519006,"about_ca_system_score_codex":0.0001732647,"about_ca_system_score_gemma":0.00017494473,"threshold_uncertainty_score":0.009205997},"labels":[],"label_agreement":null},{"id":"W4285544994","doi":"10.2139/ssrn.3962715","title":"Divergent Allostery Reveals Critical Differences between Structurally Homologous Regulatory Domains of &lt;i&gt;Plasmodium Falciparum&lt;/i&gt; and Human Protein Kinase G","year":2021,"lang":"en","type":"article","venue":"SSRN Electronic Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Plasmodium falciparum; Allosteric regulation; Biology; Homologous chromosome; Cell biology; Genetics; Gene; Malaria; Immunology; Receptor","score_opus":0.011392329089795726,"score_gpt":0.25246173330329497,"score_spread":0.24106940421349923,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4285544994","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99708813,0.0003604176,0.0011326105,0.000049068487,0.00000983219,0.00000620403,0.00013728447,0.000031847787,0.001184531],"genre_scores_gemma":[0.9981608,0.00011862418,0.0006316861,0.00005441831,0.00000432086,0.000007918901,0.00032262065,0.000012678695,0.00068701664],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999553,0.000007447129,0.0000028015374,0.000016342228,0.000008501141,0.000009610025],"domain_scores_gemma":[0.99992144,0.000014774094,0.000031999476,0.000007427464,0.0000034318068,0.000020977384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007219566,0.00029573034,0.00018756263,0.00013035088,0.0001208342,0.0002306771,0.0002803673,0.00020097102,0.001500282],"category_scores_gemma":[0.0001041718,0.00011757607,0.00019694395,0.00010281563,0.00025445683,0.00012844273,0.00020262264,0.0005148206,0.0005348593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017022055,0.000011678391,0.0002147695,0.000014309469,0.000004860716,0.00008425515,0.000015302736,0.00018712586,0.9977849,0.00043130614,0.000037457055,0.0010438142],"study_design_scores_gemma":[0.0000938772,0.0004956215,0.042332668,0.000017908631,0.000038909777,0.0018439546,0.00012946581,0.0056320312,0.9437246,0.00083110144,0.004834399,0.00002554356],"about_ca_topic_score_codex":0.00057878863,"about_ca_topic_score_gemma":0.00068083877,"teacher_disagreement_score":0.001500282,"about_ca_system_score_codex":0.0002953404,"about_ca_system_score_gemma":0.00014067744,"threshold_uncertainty_score":0.0050189495},"labels":[],"label_agreement":null},{"id":"W4291209199","doi":"10.1186/s13046-022-02427-w","title":"CD147 mediates epidermal malignant transformation through the RSK2/AP-1 pathway","year":2022,"lang":"en","type":"article","venue":"Journal of Experimental & Clinical Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SKiN Health","funders":"Postdoctoral Research Foundation of China; Higher Education Discipline Innovation Project; Cancer Research Institute; Natural Science Foundation of Hunan Province; China Postdoctoral Science Foundation; Overseas Expertise Introduction Project for Discipline Innovation; National Natural Science Foundation of China; Science and Technology Innovative Research Team in Higher Educational Institutions of Hunan Province; Central South University","keywords":"Carcinogenesis; Cancer research; Malignant transformation; HaCaT; Gene knockdown; Biology; Chemokine; Genetically modified mouse; Flow cytometry; Transgene; Apoptosis; Immunology; Cell culture; Cancer; Inflammation; Gene","score_opus":0.1557062482217561,"score_gpt":0.4894940840734959,"score_spread":0.3337878358517398,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4291209199","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96826124,0.01008676,0.011626455,0.0007068236,0.00022776292,0.00009824787,0.0018181744,0.00046517682,0.0067093507],"genre_scores_gemma":[0.99100983,0.001909977,0.0015895208,0.00010448916,0.00004179855,0.000081264094,0.0011139013,0.000020978445,0.004128254],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997613,0.00004238425,0.000023511018,0.00005149461,0.000059176913,0.00006212164],"domain_scores_gemma":[0.9998591,0.000013378728,0.000048673915,0.000019760773,0.000022823384,0.0000363862],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017121658,0.00036895173,0.0002629674,0.00035569878,0.0002682546,0.00052415824,0.000281335,0.0003601244,0.0039022276],"category_scores_gemma":[0.00013187966,0.00013947001,0.00045310816,0.0002178832,0.00023953516,0.00028947752,0.00038133335,0.000881332,0.0013554766],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041662587,0.000114902796,0.0012250339,0.0003670933,0.000022451213,0.00042788906,0.00004054169,0.0001410883,0.9915072,0.00084747205,0.0006666885,0.0042229523],"study_design_scores_gemma":[0.00009838594,0.00040872817,0.021501059,0.000056252116,0.000074861644,0.0022333397,0.0002106886,0.0053345,0.95360404,0.0008158197,0.015644316,0.00001798349],"about_ca_topic_score_codex":0.00016358399,"about_ca_topic_score_gemma":0.00013081021,"teacher_disagreement_score":0.0039022276,"about_ca_system_score_codex":0.00025512243,"about_ca_system_score_gemma":0.00018994929,"threshold_uncertainty_score":0.013054252},"labels":[],"label_agreement":null},{"id":"W4293090934","doi":"10.1093/cvr/cvac142","title":"Emerging epigenetic therapies of cardiac fibrosis and remodelling in heart failure: from basic mechanisms to early clinical development","year":2022,"lang":"en","type":"review","venue":"Cardiovascular Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"National Heart, Lung, and Blood Institute; Biomedical Research Council; National Medical Research Council; American Heart Association; Medical Research Council; National Institutes of Health; Deutsche Forschungsgemeinschaft","keywords":"Epigenetics; Heart failure; Medicine; Disease; Bioinformatics; Fibrosis; Neuroscience; Internal medicine; Biology","score_opus":0.12576042577858318,"score_gpt":0.3872193755931007,"score_spread":0.26145894981451756,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4293090934","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00017359911,0.9975048,0.00027898894,0.00047468435,0.00037795724,0.000006206226,0.000018933417,0.00001193971,0.0011530299],"genre_scores_gemma":[0.000906528,0.9973726,0.0003340905,0.00033888646,0.0002408322,0.00000990528,0.000032608423,0.0000023039374,0.00076215976],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998572,0.000029880392,0.000016278364,0.000024467618,0.00005351798,0.00001859521],"domain_scores_gemma":[0.9997465,0.00014120562,0.000021793057,0.000007823885,0.000057658275,0.00002493849],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00062313856,0.00063235656,0.0009545448,0.0011851127,0.00022310771,0.0007326297,0.00073133956,0.0010181731,0.0035717054],"category_scores_gemma":[0.00063547434,0.00018107556,0.00043605434,0.0007764221,0.00040658432,0.0011110689,0.00062529306,0.0019923646,0.0014053414],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010429144,0.000099372184,0.0001274732,0.01252772,0.00008085091,0.00020032999,0.00008023274,0.0003466342,0.005147248,0.0068776775,0.02698913,0.947419],"study_design_scores_gemma":[0.000024903406,0.00018362804,0.0006105654,0.002813162,0.00010160352,0.0008175974,0.000054844186,0.00014411604,0.0011356754,0.0032346104,0.9908619,0.000017363689],"about_ca_topic_score_codex":0.00042513967,"about_ca_topic_score_gemma":0.0010839434,"teacher_disagreement_score":0.0035717054,"about_ca_system_score_codex":0.00042756175,"about_ca_system_score_gemma":0.0007784253,"threshold_uncertainty_score":0.0119485855},"labels":[],"label_agreement":null},{"id":"W4297339151","doi":"10.1021/acs.jmedchem.2c00996","title":"Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial <i>Pf</i> GSK3/ <i>Pf</i> PK6 with Activity against Blood Stage Parasites In Vitro","year":2022,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Bayer; National Institute of Allergy and Infectious Diseases; Structural Genomics Consortium; Janssen Pharmaceuticals; Merck KGaA; Genome Canada; Genentech; Takeda Pharmaceutical Company; Bristol-Myers Squibb; Boehringer Ingelheim; National Institutes of Health; National Science Foundation","keywords":"Chemistry; IC50; In vitro; Kinase; Drug discovery; Pharmacology; EC50; Biochemistry; Biology","score_opus":0.009244600337672526,"score_gpt":0.2430039537320592,"score_spread":0.2337593533943867,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4297339151","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9424531,0.018488033,0.020288795,0.00041645436,0.00027399062,0.0006648749,0.0022268218,0.00039780556,0.014790148],"genre_scores_gemma":[0.9695859,0.007983814,0.013981502,0.00019855295,0.000043040454,0.00019385066,0.001958162,0.000029908595,0.006025292],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999243,0.0000146846005,0.000008338516,0.000013481865,0.000016110109,0.000023118606],"domain_scores_gemma":[0.99993634,0.000008808366,0.000017221275,0.000007822341,0.000009597678,0.00002025595],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025345173,0.0004714118,0.00037787703,0.00025370534,0.00014389277,0.00026701577,0.00037014778,0.0002905866,0.0033695914],"category_scores_gemma":[0.00016643268,0.00016556702,0.00024334884,0.00022222832,0.00018475304,0.00028332716,0.0002072652,0.00065856846,0.0006940637],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009333191,0.00023919571,0.00027553298,0.00037938645,0.000029440365,0.00029951008,0.000063523425,0.0013935966,0.9612962,0.0016618222,0.0007475045,0.032681018],"study_design_scores_gemma":[0.0007292004,0.008158867,0.0028617617,0.000058190308,0.00010552259,0.0015172671,0.000047180154,0.0027055717,0.9570668,0.0006291695,0.02606896,0.000051574458],"about_ca_topic_score_codex":0.00045797354,"about_ca_topic_score_gemma":0.001668702,"teacher_disagreement_score":0.0033695914,"about_ca_system_score_codex":0.00034395553,"about_ca_system_score_gemma":0.00035240955,"threshold_uncertainty_score":0.01127243},"labels":[],"label_agreement":null},{"id":"W4307280591","doi":"10.1101/2022.10.23.513420","title":"Junctophilin-2 promotes cardiomyocyte survival by blocking MURF1-mediated Junctin ubiquitination and proteasome-dependentdegradation","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"London Health Sciences Centre; Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; National Institutes of Health; Government of Jiangsu Province","keywords":"Cell biology; Internal medicine; Proteasome; Biology; Ubiquitin; Endocrinology; Biochemistry; Medicine","score_opus":0.0106197070451607,"score_gpt":0.2182832320772572,"score_spread":0.2076635250320965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4307280591","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99615437,0.0014285991,0.001329573,0.000078860394,0.000030761392,0.000023541714,0.00015520738,0.000054694796,0.0007444474],"genre_scores_gemma":[0.99541867,0.0008619292,0.0015857766,0.00006104441,0.000016049267,0.000033309418,0.00029305063,0.000012985025,0.0017173204],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991286,0.000013649073,0.000012053239,0.000025738578,0.00001573971,0.000019917665],"domain_scores_gemma":[0.9999337,0.0000069288308,0.000025582103,0.0000065751046,0.0000059471063,0.00002113322],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112528796,0.00031124902,0.0002743304,0.000119983524,0.00015503498,0.00019251824,0.00014112887,0.00025269628,0.00092437677],"category_scores_gemma":[0.000072678435,0.000102052574,0.00017868228,0.00007627343,0.00020455351,0.00018159462,0.00013663291,0.00035441844,0.00021830513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001432765,0.000025217505,0.00009074394,0.00003971476,0.0000059709587,0.000031661708,0.000006207915,0.000033080174,0.9990121,0.00003530977,0.000025278014,0.00055148295],"study_design_scores_gemma":[0.000034175377,0.0003571032,0.002657736,0.0000053700974,0.000017211669,0.00020747409,0.000015492195,0.0004939008,0.99469465,0.000022290109,0.0014916932,0.0000029905202],"about_ca_topic_score_codex":0.00016523268,"about_ca_topic_score_gemma":0.00034427916,"teacher_disagreement_score":0.00092437677,"about_ca_system_score_codex":0.00018797998,"about_ca_system_score_gemma":0.00012725643,"threshold_uncertainty_score":0.0030923486},"labels":[],"label_agreement":null},{"id":"W4308179351","doi":"10.1161/hypertensionaha.122.19411","title":"Loss of ADAM15 Exacerbates Transition to Decompensated Myocardial Hypertrophy and Dilation Through Activation of the Calcineurin Pathway","year":2022,"lang":"en","type":"article","venue":"Hypertension","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute; University of Calgary; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; China Scholarship Council","keywords":"Muscle hypertrophy; Pressure overload; Internal medicine; Biology; Endocrinology; Cardiomyopathy; Cell biology; Heart failure; Medicine; Cardiac hypertrophy","score_opus":0.01583454443201287,"score_gpt":0.22208308508384017,"score_spread":0.2062485406518273,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308179351","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99762803,0.00083658425,0.0006448677,0.00010270427,0.0000420355,0.000024869087,0.00020766589,0.00007481057,0.00043846652],"genre_scores_gemma":[0.9970782,0.000513417,0.00066099246,0.00006265876,0.00002000186,0.000034812976,0.00033890904,0.000015310356,0.0012758387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99978894,0.000034925335,0.000037458874,0.00003995459,0.00003873588,0.000060010643],"domain_scores_gemma":[0.99964356,0.00002116129,0.00012616014,0.000022130507,0.00001696441,0.00017002804],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022523156,0.00057383976,0.00046529292,0.00033744142,0.00015485326,0.00032134372,0.00020963929,0.00039020658,0.0025129772],"category_scores_gemma":[0.00015208391,0.00021241675,0.0003561268,0.00012623493,0.00033710396,0.00026660188,0.00026063135,0.00095177226,0.00035096434],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086008926,0.00015572384,0.0011101018,0.00007873981,0.000023598684,0.0003555993,0.000037256144,0.00006202288,0.995905,0.000081107915,0.00009725601,0.0012333976],"study_design_scores_gemma":[0.0002739428,0.006162453,0.074119896,0.000076805314,0.00021374645,0.004149659,0.00022920255,0.0018517091,0.9083394,0.00022507396,0.0043367394,0.000021324182],"about_ca_topic_score_codex":0.00022932036,"about_ca_topic_score_gemma":0.00041772512,"teacher_disagreement_score":0.0025129772,"about_ca_system_score_codex":0.00023597603,"about_ca_system_score_gemma":0.00017040825,"threshold_uncertainty_score":0.008406818},"labels":[],"label_agreement":null},{"id":"W4308366794","doi":"10.1139/cjpp-2022-0172","title":"Smoothelin-like 1 knockout mice display sex-dependent alterations in blood flow and cardiac function","year":2022,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Isovolumetric contraction; Internal medicine; Cardiac function curve; Ventricle; Cardiology; Pressure overload; Endocrinology; Medicine; Blood pressure; Muscle hypertrophy; Heart failure; Diastole; Cardiac hypertrophy","score_opus":0.007546100786596271,"score_gpt":0.23646091271793832,"score_spread":0.22891481193134205,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308366794","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99251807,0.0012964339,0.0027408192,0.00016670299,0.00005363319,0.000023238423,0.0017360896,0.00016134632,0.0013037975],"genre_scores_gemma":[0.9797365,0.0020540736,0.0039444854,0.00019891675,0.000048255384,0.00017349547,0.002291535,0.00014629972,0.011406489],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99966896,0.00003073178,0.000036911035,0.000117685115,0.000083349914,0.00006243674],"domain_scores_gemma":[0.9995308,0.00003150554,0.0002379092,0.000024425364,0.00002899483,0.0001464062],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026606608,0.00060716906,0.00040053012,0.0010516238,0.00022600731,0.0004052188,0.0003123477,0.0005595405,0.003255945],"category_scores_gemma":[0.00019873674,0.00032733704,0.00036662922,0.00026943136,0.00041667777,0.00033460508,0.000383389,0.0012233747,0.0005353084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004098363,0.000059488684,0.0015248614,0.000045701123,0.000009943776,0.00020605428,0.000068839676,0.000029617235,0.99521697,0.00012053544,0.00007215135,0.0022360573],"study_design_scores_gemma":[0.0001725599,0.0019760935,0.16853046,0.00007370304,0.00015925628,0.003171274,0.00035540288,0.0011856669,0.8179375,0.0005251562,0.0058486937,0.00006424939],"about_ca_topic_score_codex":0.00032801306,"about_ca_topic_score_gemma":0.00068402267,"teacher_disagreement_score":0.003255945,"about_ca_system_score_codex":0.00021298439,"about_ca_system_score_gemma":0.00019507244,"threshold_uncertainty_score":0.010892212},"labels":[],"label_agreement":null},{"id":"W4308931580","doi":"10.1016/j.biopha.2022.113983","title":"CD147 and MMPs as key factors in physiological and pathological processes","year":2022,"lang":"en","type":"review","venue":"Biomedicine & Pharmacotherapy","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Carl Tryggers Stiftelse för Vetenskaplig Forskning; Vetenskapsrådet; Canadian Thoracic Society","keywords":"Matrix metalloproteinase; Proteases; Extracellular matrix; Cell biology; Extracellular; Metalloproteinase; Transmembrane protein; Receptor; Chemistry; Function (biology); Enzyme; Biology; Biochemistry","score_opus":0.08802739977768373,"score_gpt":0.3945371553869982,"score_spread":0.3065097556093145,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4308931580","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00014801633,0.99801636,0.00012627397,0.0002085805,0.0002016027,0.000004025958,0.000018167391,0.000006806187,0.0012702245],"genre_scores_gemma":[0.0008012741,0.9976956,0.00018131796,0.00015064306,0.0001789446,0.0000063243524,0.000035114335,0.0000014788568,0.0009493326],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998764,0.000019088377,0.000018279494,0.000022696322,0.000048610134,0.000014995032],"domain_scores_gemma":[0.9998851,0.000041124476,0.000016513142,0.0000037782465,0.000037265996,0.000016104561],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027641444,0.00061105605,0.0007889986,0.0020906606,0.00025006465,0.0009415738,0.00049102725,0.00082959194,0.0034552356],"category_scores_gemma":[0.0003659825,0.0001660885,0.00029135423,0.0020490198,0.00028096643,0.0009812966,0.00051587826,0.0011846736,0.0019896973],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008625901,0.00006575759,0.00020377677,0.014521102,0.000057909132,0.00034852372,0.00008589961,0.00023850494,0.0041794977,0.005078766,0.032536652,0.9425973],"study_design_scores_gemma":[0.000008525317,0.00006801726,0.0006473963,0.0017524458,0.00005711269,0.0016951669,0.000052779367,0.000055146076,0.0006257339,0.0016528257,0.9933729,0.0000118958915],"about_ca_topic_score_codex":0.00051994825,"about_ca_topic_score_gemma":0.0009223256,"teacher_disagreement_score":0.0034552356,"about_ca_system_score_codex":0.00041659872,"about_ca_system_score_gemma":0.0008603762,"threshold_uncertainty_score":0.01155889},"labels":[],"label_agreement":null},{"id":"W4309455496","doi":"10.3390/ijms232214214","title":"MT1-MMP Expression Levels and Catalytic Functions Dictate LDL Receptor-Related Protein-1 Ligand Internalization Capacity in U87 Glioblastoma Cells","year":2022,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Internalization; Glioblastoma; Ligand (biochemistry); Matrix metalloproteinase; Chemistry; Cell biology; Receptor; U87; Cancer research; Biochemistry; Biology","score_opus":0.016823027642376875,"score_gpt":0.24865701103914278,"score_spread":0.23183398339676592,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4309455496","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99651825,0.0011106688,0.0007608825,0.000032563963,0.000007842334,0.000021712,0.0003519931,0.000041067462,0.0011550671],"genre_scores_gemma":[0.9955681,0.0007017924,0.001071071,0.000026547577,0.0000033782146,0.000047597572,0.000626105,0.0000072417947,0.0019482693],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998103,0.000022270877,0.00002825909,0.00002190405,0.00005206433,0.00006520945],"domain_scores_gemma":[0.99993813,0.0000099749905,0.000015864405,0.000007265568,0.000015481573,0.000013256219],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011449921,0.00024026803,0.00033437676,0.00027081824,0.00015612342,0.00036384337,0.000093026014,0.00018927528,0.0005276318],"category_scores_gemma":[0.00010336604,0.00015375213,0.00023664135,0.00030328584,0.0001235507,0.00015329904,0.00012916714,0.00030375257,0.0003142144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014448515,0.000038535196,0.00087415904,0.000033428434,0.000007148193,0.00005022152,0.00006112346,0.000097609634,0.99730575,0.00005998091,0.00005775155,0.001269762],"study_design_scores_gemma":[0.000010606851,0.0003398536,0.020552294,0.0000056255253,0.00003002606,0.00017073918,0.000106931264,0.0011780998,0.9762033,0.000025466314,0.0013704626,0.0000065962145],"about_ca_topic_score_codex":0.005852759,"about_ca_topic_score_gemma":0.005442684,"teacher_disagreement_score":0.005852759,"about_ca_system_score_codex":0.00036319965,"about_ca_system_score_gemma":0.00025121792,"threshold_uncertainty_score":0.01163739},"labels":[],"label_agreement":null},{"id":"W4310384227","doi":"10.1186/s12888-022-04392-2","title":"The association of FKBP5 gene methylation, adolescents’ sex, and depressive symptoms among Chinese adolescents: a nested case-control study","year":2022,"lang":"en","type":"article","venue":"BMC Psychiatry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University Health Network","funders":"Natural Science Foundation of Guangdong Province; National Natural Science Foundation of China","keywords":"FKBP5; DNA methylation; Methylation; Medicine; Case-control study; Longitudinal study; Depressive symptoms; CpG site; Nested case-control study; Clinical psychology; Psychiatry; Internal medicine; Genetics; Gene; Biology; Glucocorticoid receptor; Cognition; Pathology","score_opus":0.0045593699098741515,"score_gpt":0.23620594094980846,"score_spread":0.2316465710399343,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4310384227","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99952936,0.00013742819,0.00012312853,0.000012265486,0.0000035042578,0.000034116314,0.00008716052,0.0000014582032,0.000071583505],"genre_scores_gemma":[0.99939466,0.000078431025,0.00018957688,0.000025396206,0.0000052891005,0.00004503773,0.0001778337,0.000001111476,0.00008263255],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.9992267,0.0001387209,0.000097619864,0.00031641623,0.00012885772,0.0000915872],"domain_scores_gemma":[0.9994205,0.00007241258,0.00017102851,0.0001244634,0.000100576624,0.00011096301],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0011819893,0.00045759106,0.0005586429,0.0007140522,0.0011373363,0.0004922612,0.0006263825,0.00045788038,0.00067902246],"category_scores_gemma":[0.0011918315,0.000596995,0.0006929388,0.0007064295,0.0005203712,0.00021464119,0.00039806828,0.0003328936,0.00008174328],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016084657,0.00006591103,0.9977654,0.000018611816,0.00013504938,0.00021808811,0.00027870017,0.000017119342,0.00065733166,0.000025956351,0.000053897616,0.0006030623],"study_design_scores_gemma":[0.000045764573,0.00021476022,0.9982243,0.000009108852,0.00022568945,0.0004423358,0.00021423961,0.00022424237,0.000150251,0.000022310871,0.00022215572,0.000004777167],"about_ca_topic_score_codex":0.021139136,"about_ca_topic_score_gemma":0.027109392,"teacher_disagreement_score":0.021139136,"about_ca_system_score_codex":0.0006716986,"about_ca_system_score_gemma":0.0007445017,"threshold_uncertainty_score":0.042032182},"labels":[],"label_agreement":null},{"id":"W4312102451","doi":"10.21203/rs.3.rs-2397012/v1","title":"The Peptidyl-Prolyl cis-trans Isomerase, Pin1, Associates with Protein Kinase C θ (PKCθ) via a Critical Phospho-Thr-Pro Motif in the V3 Regulatory Domain","year":2022,"lang":"en","type":"preprint","venue":"Research Square","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université du Québec à Montréal","funders":"Ben-Gurion University of the Negev; Kreitman School of Advanced Graduate Studies, Ben-Gurion University of the Negev; Israel Science Foundation; United States-Israel Binational Science Foundation; Israel Cancer Research Fund","keywords":"PIN1; Protein kinase C; Phosphorylation; Prolyl isomerase; Biology; Cell biology; Kinase; WW domain; Isomerase; Mutant; Peptidylprolyl isomerase; Biochemistry; Chemistry; Enzyme; Gene","score_opus":0.029040815763161476,"score_gpt":0.35064419040369543,"score_spread":0.32160337464053396,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4312102451","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9947437,0.0012232364,0.0028151025,0.000079948106,0.000026478456,0.000023356997,0.00015896244,0.000051244235,0.00087793637],"genre_scores_gemma":[0.9952773,0.00051281776,0.0019650422,0.00005640277,0.000011092423,0.000023645132,0.00038548524,0.000012081084,0.0017561755],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998579,0.000018959594,0.000008713078,0.000044220655,0.000031879903,0.000038332062],"domain_scores_gemma":[0.99987555,0.000011851204,0.00006181822,0.00000712191,0.0000056987233,0.000037897025],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011478737,0.00058419514,0.00019614861,0.00019097826,0.0002015148,0.00027557954,0.0003030621,0.0002906207,0.0017562212],"category_scores_gemma":[0.00012375881,0.0002478543,0.00040015494,0.00014218598,0.00021594613,0.00018599683,0.00031386619,0.0005162282,0.00072169484],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018749096,0.000022452434,0.00045049313,0.000050582916,0.000008143886,0.00012092127,0.000007037804,0.00008133824,0.9982712,0.00009618561,0.000029642642,0.00067445106],"study_design_scores_gemma":[0.000024640414,0.00021215482,0.015628614,0.00001141563,0.000019423866,0.0010547715,0.000033930202,0.0020620918,0.9784896,0.00009723628,0.0023581404,0.000007907829],"about_ca_topic_score_codex":0.00035472165,"about_ca_topic_score_gemma":0.0003581383,"teacher_disagreement_score":0.0017562212,"about_ca_system_score_codex":0.00036922726,"about_ca_system_score_gemma":0.000157809,"threshold_uncertainty_score":0.00587517},"labels":[],"label_agreement":null},{"id":"W4313288624","doi":"10.1021/acs.jmedchem.2c01803","title":"Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction","year":2022,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Janssen Biotech; H2020 Marie Skłodowska-Curie Actions; Genentech; Deutsche Forschungsgemeinschaft; Ontario Genomics Institute; Takeda Pharmaceutical Company; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Genomics; Genome Canada; Bayer; Bristol-Myers Squibb; Pfizer; McGill University; Boehringer Ingelheim","keywords":"Chemistry; PDZ domain; Peptide; Postsynaptic density; NMDA receptor; Cyclic peptide; Peptide Conformation; Amino acid; Biophysics; Biochemistry; Receptor","score_opus":0.01214040825009691,"score_gpt":0.2519791585186862,"score_spread":0.23983875026858928,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313288624","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9733883,0.005378775,0.014923221,0.00012316108,0.00008527662,0.00029967344,0.0003408785,0.00014184746,0.0053189048],"genre_scores_gemma":[0.9840958,0.0024865256,0.010769161,0.00012204838,0.000022156208,0.00013446515,0.00048020284,0.000014576447,0.001875051],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999473,0.0000060786024,0.000005056264,0.00001286234,0.00001532796,0.000013335183],"domain_scores_gemma":[0.9999678,0.0000042502934,0.000008851473,0.0000022457855,0.0000052892633,0.000011577297],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000093246,0.00030845185,0.00024739062,0.00013348211,0.00008562292,0.00012211833,0.00027599445,0.0001803713,0.00080309773],"category_scores_gemma":[0.000094114395,0.000100342055,0.00013735805,0.0000979011,0.00010540434,0.00011788794,0.00015189797,0.00033709002,0.00017917158],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012414009,0.00007563591,0.00007792515,0.00007342582,0.000010998366,0.000074627,0.00000988361,0.0006821978,0.99160767,0.00023445609,0.00011084748,0.006918223],"study_design_scores_gemma":[0.00013860651,0.0020416845,0.00093331217,0.000010641229,0.00003444925,0.00039180173,0.000010113988,0.0035481574,0.9858801,0.00009034604,0.0069081476,0.00001270152],"about_ca_topic_score_codex":0.00025578245,"about_ca_topic_score_gemma":0.00050305214,"teacher_disagreement_score":0.00080309773,"about_ca_system_score_codex":0.00018442549,"about_ca_system_score_gemma":0.00017949921,"threshold_uncertainty_score":0.0026865602},"labels":[],"label_agreement":null},{"id":"W4313386300","doi":"10.4049/jimmunol.190.supp.184.5","title":"Suppressor of cytokine signaling proteins are induced by IL-7 and regulate CD127 expression in human CD8 T cells (P6291)","year":2013,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ottawa Public Health; Ottawa Hospital; University of Ottawa","funders":"","keywords":"Interleukin-7 receptor; Ubiquitin ligase; STAT5; Biology; Cell biology; CD8; Signal transduction; T cell; Molecular biology; Ubiquitin; IL-2 receptor; Immunology; Immune system; Genetics; Gene","score_opus":0.01044857871532209,"score_gpt":0.23147599068991517,"score_spread":0.22102741197459308,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313386300","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949411,0.00091364497,0.0018605315,0.00008717337,0.000025849453,0.00003312333,0.00035168818,0.000068108195,0.0017187595],"genre_scores_gemma":[0.9950262,0.00032128103,0.0012496567,0.00004165919,0.000010422945,0.000060341015,0.0006485641,0.000015879215,0.0026259895],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999008,0.000012735183,0.000007713142,0.000017892864,0.00002660535,0.00003419184],"domain_scores_gemma":[0.99994946,0.0000070688698,0.000013964737,0.0000055148103,0.00000876449,0.000015162685],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007877385,0.00023073495,0.00012569298,0.0001728029,0.00011636321,0.00019599324,0.00007907995,0.00019327231,0.0020691503],"category_scores_gemma":[0.0000777151,0.0000816765,0.00017337147,0.00008467569,0.00013247164,0.00008803984,0.00016208907,0.00042325063,0.00065778155],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015457527,0.00001719355,0.00020976417,0.00002618762,0.000002216018,0.000060131348,0.000020304155,0.0000370766,0.99829596,0.00007238865,0.000056184403,0.0010479705],"study_design_scores_gemma":[0.000057808014,0.000421967,0.008742643,0.000009874584,0.00001499983,0.00043564284,0.000054080683,0.0014835473,0.9848813,0.000086758686,0.003807246,0.000004137344],"about_ca_topic_score_codex":0.00024742528,"about_ca_topic_score_gemma":0.00031252016,"teacher_disagreement_score":0.0020691503,"about_ca_system_score_codex":0.0001436904,"about_ca_system_score_gemma":0.00013683343,"threshold_uncertainty_score":0.0069220066},"labels":[],"label_agreement":null},{"id":"W4313396982","doi":"10.1016/j.yjmcc.2022.08.093","title":"Proteomic approaches to assess ischemia-reperfusion (stunning) injury to the heart","year":2022,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Stunning; Myocardial stunning; Ischemia; Endoplasmic reticulum; Reperfusion injury; Myocyte; Cardiology; Titin; Matrix metalloproteinase; Troponin I; Medicine; Internal medicine; Proteases; Cardiac muscle; Sarcomere; Chemistry; Biology; Myocardial infarction; Cell biology; Biochemistry; Enzyme","score_opus":0.0397891956993141,"score_gpt":0.24501718693748717,"score_spread":0.20522799123817306,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4313396982","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8406147,0.03259077,0.10497567,0.0014066391,0.00065199053,0.00061818055,0.00392445,0.00039717497,0.014820519],"genre_scores_gemma":[0.8406638,0.024743484,0.11563549,0.0014822959,0.00043413925,0.0008716511,0.0031197395,0.00014723968,0.012902235],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99969506,0.00005953055,0.000026595691,0.00006255478,0.00009771741,0.00005861052],"domain_scores_gemma":[0.99978477,0.00003714188,0.000048205955,0.00001544658,0.00006218741,0.00005229429],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006186804,0.00067047507,0.00046554775,0.0015539756,0.00058048853,0.0008669697,0.00040685863,0.00058706634,0.0017590524],"category_scores_gemma":[0.00039912137,0.0003727958,0.0005099664,0.00078699144,0.00036061532,0.00065778504,0.0004627125,0.0012375189,0.000759427],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001736779,0.00005794187,0.0006167992,0.00014329569,0.00003817566,0.0000566442,0.000028199833,0.00004813423,0.99523914,0.00026111453,0.00010062322,0.0032362181],"study_design_scores_gemma":[0.00004689423,0.00073591404,0.04917819,0.000060480892,0.00022580397,0.0013740642,0.0002801859,0.002544174,0.93857425,0.0010131125,0.005934868,0.000032121032],"about_ca_topic_score_codex":0.0005733668,"about_ca_topic_score_gemma":0.0015602339,"teacher_disagreement_score":0.0017590524,"about_ca_system_score_codex":0.0003505858,"about_ca_system_score_gemma":0.00040268613,"threshold_uncertainty_score":0.0058845878},"labels":[],"label_agreement":null},{"id":"W4315707288","doi":"10.21203/rs.3.rs-2410384/v1","title":"Plasmepsin X activates function of the PCRCR complex in P. falciparum by processing PfRh5 for binding to basigin and invasion of human erythrocytes","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"National Health and Medical Research Council; Medical Research Council","keywords":"Basigin; Function (biology); Computational biology; Cell biology; Chemistry; Biology; Molecular biology; Biochemistry","score_opus":0.15935504692144367,"score_gpt":0.41565586112287034,"score_spread":0.2563008142014267,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315707288","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950675,0.00039088566,0.001802482,0.00016170555,0.000026149448,0.000012540625,0.0004884156,0.000064976906,0.0019853385],"genre_scores_gemma":[0.9911691,0.00019245065,0.0012919644,0.000039642688,0.0000076747,0.000009963733,0.0011103286,0.0000344012,0.006144502],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999002,0.000014142781,0.0000058207934,0.000024237119,0.000017548313,0.000038051185],"domain_scores_gemma":[0.99995446,0.000010211961,0.000009325039,0.0000067630967,0.000004201425,0.000015100334],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012568723,0.00031891585,0.00013148262,0.00013410725,0.00021162348,0.0003286814,0.00018679752,0.00024356028,0.0057902983],"category_scores_gemma":[0.00018633588,0.00018027106,0.00018999456,0.00009353097,0.00015352521,0.00022114444,0.00031435583,0.00045309067,0.00112894],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000405885,0.00001765617,0.00041292835,0.000037017307,0.0000064165233,0.00023106513,0.000026453386,0.00010640279,0.9969971,0.00046687125,0.00029520554,0.0009969304],"study_design_scores_gemma":[0.000052645704,0.000096365045,0.01945706,0.000006705941,0.0000088518755,0.0004148989,0.0000746797,0.002692577,0.9740563,0.00020986606,0.002923679,0.000006362386],"about_ca_topic_score_codex":0.001278212,"about_ca_topic_score_gemma":0.0011254525,"teacher_disagreement_score":0.0057902983,"about_ca_system_score_codex":0.0003527218,"about_ca_system_score_gemma":0.00017751462,"threshold_uncertainty_score":0.019370437},"labels":[],"label_agreement":null},{"id":"W4315795805","doi":"10.3390/biom13010152","title":"FK506-Binding Protein 2 Participates in Proinsulin Folding","year":2023,"lang":"en","type":"article","venue":"Biomolecules","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Punjab Educational Endowment Fund; Augustinus Fonden","keywords":"Proinsulin; Protein folding; Foldase; Chaperone (clinical); Chemistry; Biochemistry; Protein disulfide-isomerase; Cell biology; Insulin; Biology; Enzyme; Endocrinology; Gene; GroEL","score_opus":0.028211738774592515,"score_gpt":0.2932038944211096,"score_spread":0.2649921556465171,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4315795805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96509296,0.017309712,0.011858726,0.0004911697,0.00012205897,0.000040845818,0.000604891,0.00023055922,0.0042491164],"genre_scores_gemma":[0.9916991,0.002178488,0.0028691613,0.000057956768,0.000022480564,0.000011538952,0.00035555396,0.000009283949,0.002796462],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999099,0.000013388712,0.0000069750613,0.00003497086,0.000012914267,0.000021813588],"domain_scores_gemma":[0.99995005,0.000005392835,0.000016047943,0.00000466352,0.000007631811,0.000016202539],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000076938704,0.00043900326,0.00021895654,0.0001912786,0.00032059767,0.00031617453,0.00011762698,0.00039687092,0.0011887024],"category_scores_gemma":[0.000073138974,0.000108590284,0.00023966172,0.00014532448,0.00013647744,0.00020142511,0.00015767828,0.00023219925,0.0005994913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036115362,0.000033816137,0.0023719778,0.00011645386,0.000016715554,0.00050584914,0.00003302488,0.00019163336,0.988947,0.0005459116,0.00024170658,0.006634895],"study_design_scores_gemma":[0.00004197783,0.0003905329,0.07172764,0.000027964385,0.00005182597,0.003349506,0.000108422355,0.0030953563,0.904601,0.00096007844,0.015617256,0.000028509654],"about_ca_topic_score_codex":0.0008924527,"about_ca_topic_score_gemma":0.0006219284,"teacher_disagreement_score":0.0011887024,"about_ca_system_score_codex":0.0003212022,"about_ca_system_score_gemma":0.0001731382,"threshold_uncertainty_score":0.0039765835},"labels":[],"label_agreement":null},{"id":"W4317472263","doi":"10.21203/rs.3.rs-2447544/v1","title":"Reciprocal inhibition of PIN1 and APC/CCDH1 controls timely G1/S transition and creates therapeutic vulnerability","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Ludwig Center at Harvard; Beth Israel Deaconess Medical Center; Owens Family Foundation; Breast Cancer Research Foundation","keywords":"Vulnerability (computing); Transition (genetics); Reciprocal; PIN1; Medicine; Computer science; Chemistry; Computer security; Biochemistry; Philosophy","score_opus":0.07739731488807716,"score_gpt":0.38600130102854385,"score_spread":0.3086039861404667,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317472263","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9561037,0.006028471,0.01177172,0.0012163261,0.00049286237,0.0001118247,0.0013827326,0.0011447349,0.021747658],"genre_scores_gemma":[0.9952872,0.00064957765,0.0013413035,0.00010196652,0.000019474297,0.00003232839,0.00022016515,0.00007541692,0.002272596],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99967015,0.000019587555,0.000013475288,0.00008999565,0.00008686675,0.00011999563],"domain_scores_gemma":[0.9998172,0.000028614084,0.000050307146,0.000023201912,0.000014985566,0.00006567154],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024466982,0.00040178504,0.00047761612,0.00048172133,0.00030434944,0.0011711641,0.00040362772,0.0005961382,0.005756528],"category_scores_gemma":[0.0005208322,0.0003143543,0.00024934398,0.00021659755,0.00045042182,0.0005379279,0.00074185716,0.0010786308,0.0010838375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001161335,0.0000696893,0.00077442155,0.00012439181,0.000022261083,0.00028147988,0.000026900487,0.00066347583,0.9782305,0.0036187517,0.0012691686,0.013757605],"study_design_scores_gemma":[0.00011700242,0.00030923434,0.007238884,0.000019771858,0.00004762176,0.0007492873,0.000074233154,0.0049030744,0.97227657,0.0020966448,0.012144777,0.000022914615],"about_ca_topic_score_codex":0.00035657795,"about_ca_topic_score_gemma":0.0005526722,"teacher_disagreement_score":0.005756528,"about_ca_system_score_codex":0.0006649506,"about_ca_system_score_gemma":0.00038001186,"threshold_uncertainty_score":0.019257486},"labels":[],"label_agreement":null},{"id":"W4317761884","doi":"10.1101/2023.01.23.525163","title":"Caltubin regulates microtubule stability via Ca <sup>2+</sup> -dependent mechanisms favouring neurite regrowth","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Windsor; Structural Genomics Consortium; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Neurite; Microtubule; Lymnaea stagnalis; Tubulin; Cell biology; Calmodulin; Tyrosine; Biology; Calcium; Chemistry; Biochemistry; Snail","score_opus":0.01596200510075371,"score_gpt":0.21717883386166806,"score_spread":0.20121682876091435,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4317761884","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9939693,0.0010265906,0.0021824797,0.00016430218,0.000028445935,0.0000113226315,0.00023595252,0.00012964914,0.0022520127],"genre_scores_gemma":[0.99373347,0.00030677902,0.0015304307,0.00004142836,0.000008774195,0.000012409108,0.0003200495,0.00003382694,0.004012814],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999404,0.0000055596774,0.0000028289774,0.000014870326,0.000019578596,0.000016724549],"domain_scores_gemma":[0.99993944,0.00000996888,0.000016095886,0.000004540733,0.0000075972293,0.00002228221],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009261179,0.00015973758,0.00012775029,0.00016476007,0.00021970562,0.00033795575,0.00014778279,0.0002089072,0.0017991953],"category_scores_gemma":[0.0000876372,0.000079963924,0.00009918128,0.00012488548,0.00021649164,0.0001563925,0.00016736715,0.00026404922,0.00040259442],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005358809,0.000007234164,0.00014213026,0.00001353674,0.0000011010683,0.000036758796,0.0000039119586,0.000036368678,0.99921167,0.00010799241,0.00004184388,0.0003438377],"study_design_scores_gemma":[0.00001899898,0.000044347944,0.006986503,0.00000408398,0.0000030684125,0.00011022892,0.000014597091,0.0019033366,0.98889565,0.00013170372,0.0018849684,0.0000024829715],"about_ca_topic_score_codex":0.0005812645,"about_ca_topic_score_gemma":0.001143308,"teacher_disagreement_score":0.0017991953,"about_ca_system_score_codex":0.00035302137,"about_ca_system_score_gemma":0.00013504297,"threshold_uncertainty_score":0.0060189366},"labels":[],"label_agreement":null},{"id":"W4318612333","doi":"10.2139/ssrn.4319531","title":"Cancer Cell Extravasation Requires Iplectin Mediated Choreography of MT1-MMP at Invadopodia","year":2023,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph; Health Sciences Centre; University of Toronto; University of Windsor; Sunnybrook Health Science Centre","funders":"","keywords":"Invadopodia; Extravasation; Matrix metalloproteinase; Cancer; Choreography; Cell biology; Cancer research; Cancer cell; Medicine; Pathology; Biology; Internal medicine; Art","score_opus":0.018546526091737157,"score_gpt":0.2719219027065552,"score_spread":0.253375376614818,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4318612333","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95719564,0.0026591755,0.017600313,0.0005536925,0.0001132791,0.00006786879,0.0007350122,0.0003802901,0.020694733],"genre_scores_gemma":[0.974051,0.0011569484,0.0075685326,0.000086377964,0.000027254837,0.000054881195,0.00058881904,0.0001363362,0.0163298],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998338,0.00001539601,0.0000057724137,0.000051907504,0.00003895664,0.000054171633],"domain_scores_gemma":[0.9998299,0.00004754495,0.000038048005,0.000027933738,0.000019676776,0.0000369706],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014755047,0.00045956342,0.00021030898,0.00037694443,0.00042183904,0.0007137144,0.0002990721,0.00052052893,0.0050125476],"category_scores_gemma":[0.00028724544,0.0003602365,0.00028808744,0.00025611263,0.00034993098,0.0005672162,0.0007171855,0.0009918285,0.0022139035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011292534,0.000013509588,0.0003079296,0.0000687428,0.0000069975154,0.00036836197,0.00006802716,0.00021250719,0.99507755,0.0013635966,0.0002781164,0.0021217274],"study_design_scores_gemma":[0.000025191934,0.000060636554,0.006881951,0.000010497164,0.000008100008,0.0007912885,0.000064742955,0.0027018161,0.9823644,0.0004603469,0.0066181277,0.000012954409],"about_ca_topic_score_codex":0.0014587409,"about_ca_topic_score_gemma":0.0013083634,"teacher_disagreement_score":0.0050125476,"about_ca_system_score_codex":0.0007191786,"about_ca_system_score_gemma":0.0002509259,"threshold_uncertainty_score":0.016768634},"labels":[],"label_agreement":null},{"id":"W4320931330","doi":"10.5281/zenodo.4300712","title":"Cyclophilin D promotes disease tolerance to influenza A virus infection by licensing NK cell development and function","year":2020,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Function (biology); Virology; Virus; Cyclophilin A; Disease; Biology; Cell function; Cell; Immunology; Cell biology; Medicine; Genetics; Internal medicine","score_opus":0.02607230258112011,"score_gpt":0.23247916853788653,"score_spread":0.2064068659567664,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4320931330","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.039640684,0.0011778466,0.043038998,0.0010877687,0.00087709446,0.00019241557,0.81485707,0.07749426,0.021633869],"genre_scores_gemma":[0.10373368,0.0010851561,0.047378127,0.0009850165,0.00010804714,0.0006841853,0.785581,0.032416526,0.02802836],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9994746,0.000038373902,0.000035967732,0.00019932615,0.00016476943,0.00008693179],"domain_scores_gemma":[0.99943405,0.0002535589,0.000039687755,0.00011134083,0.00006841556,0.000092937415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006393123,0.0008068563,0.0008779462,0.0007370186,0.0009908146,0.0016899494,0.0007706125,0.0008327267,0.12695643],"category_scores_gemma":[0.0015610408,0.0008396467,0.0010454302,0.00063971797,0.00028671653,0.0010616523,0.0013298026,0.0014330865,0.06193799],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0025764722,0.00012784352,0.012709422,0.0029567345,0.00018913519,0.0003801167,0.00028211286,0.0037743978,0.30073857,0.0048584705,0.60927117,0.062135603],"study_design_scores_gemma":[0.00090821274,0.00044820592,0.04375137,0.0005949698,0.00021988948,0.0010025678,0.00024221545,0.022099657,0.35393423,0.005769613,0.5708226,0.00020645538],"about_ca_topic_score_codex":0.0030330054,"about_ca_topic_score_gemma":0.00648055,"teacher_disagreement_score":0.12695643,"about_ca_system_score_codex":0.00073109014,"about_ca_system_score_gemma":0.0012067725,"threshold_uncertainty_score":0.42471159},"labels":[],"label_agreement":null},{"id":"W4321793637","doi":"10.1016/j.jbc.2023.103064","title":"Gβγ subunits colocalize with RNA polymerase II and regulate transcription in cardiac fibroblasts","year":2023,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada; McGill University; Faculty of Medicine, McGill University; University of Texas Southwestern Medical Center","keywords":"Colocalization; Transcription (linguistics); RNA polymerase II; Polymerase; Cell biology; Molecular biology; RNA polymerase I; RNA polymerase; Protein subunit; Chemistry; Biology; RNA; Genetics; Gene expression; Gene; Promoter","score_opus":0.014983621489123819,"score_gpt":0.233041524300999,"score_spread":0.21805790281187518,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4321793637","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98186964,0.0052427663,0.008103345,0.00029195973,0.00006589232,0.00003073397,0.00052639435,0.0001255326,0.0037437747],"genre_scores_gemma":[0.9940035,0.0010937599,0.001860368,0.00013441427,0.000015945969,0.000031635773,0.00037717476,0.000021915861,0.0024612637],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998122,0.000019851605,0.0000104849405,0.00007471888,0.00004493875,0.00003778788],"domain_scores_gemma":[0.999928,0.000016107879,0.000018183,0.000014042749,0.000007807929,0.000015792424],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00010596183,0.00022851626,0.00017516689,0.00032383605,0.00019989257,0.00040109255,0.00012188427,0.0002122483,0.0008984361],"category_scores_gemma":[0.00012474624,0.00026924547,0.00022999958,0.00014881676,0.00030120817,0.000111414214,0.00019152844,0.0003845477,0.00044240293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00003281694,0.000004194371,0.000327164,0.000011447243,0.0000031088994,0.000030768566,0.000019089666,0.00003791672,0.9988851,0.00008507749,0.00003389265,0.0005295105],"study_design_scores_gemma":[0.000028494129,0.00009085605,0.030900255,0.000013708215,0.000018752049,0.00033044018,0.00012481073,0.0013375616,0.96299225,0.00028767955,0.0038666627,0.000008589907],"about_ca_topic_score_codex":0.0017301973,"about_ca_topic_score_gemma":0.0028634025,"teacher_disagreement_score":0.0017301973,"about_ca_system_score_codex":0.00050071185,"about_ca_system_score_gemma":0.00025417944,"threshold_uncertainty_score":0.003632903},"labels":[],"label_agreement":null},{"id":"W4324370103","doi":"10.1016/j.imbio.2023.152377","title":"Mice with double knockout of Egr-1 and RCAN1 exhibit reduced inflammation during Pseudomonas aeruginosa lung infection","year":2023,"lang":"en","type":"article","venue":"Immunobiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"National Natural Science Foundation of China","keywords":"Pseudomonas aeruginosa; Proinflammatory cytokine; Inflammation; Immune system; Biology; Immunology; Microbiology; Knockout mouse; Gene; Bacteria; Biochemistry","score_opus":0.008222186169965024,"score_gpt":0.2431713860058479,"score_spread":0.23494919983588286,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4324370103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9888226,0.0016946396,0.004871898,0.000436543,0.00016235153,0.000038404647,0.0018365183,0.0004992607,0.001637899],"genre_scores_gemma":[0.97446436,0.001214331,0.0063793785,0.00029219445,0.00005235047,0.00013083704,0.0015657825,0.00037746443,0.015523387],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991947,0.000068675006,0.000079555684,0.00021627414,0.0002119507,0.00022886845],"domain_scores_gemma":[0.99889106,0.00008120715,0.00046055322,0.00008296416,0.00005882035,0.00042534314],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035235294,0.0014893756,0.0009969985,0.0017912912,0.00038743013,0.00081652874,0.0007297272,0.0013947263,0.004028623],"category_scores_gemma":[0.00029467183,0.0006432686,0.00063179777,0.0004746061,0.001121997,0.00067217444,0.0006568932,0.0023423121,0.0013665941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00033397635,0.00004062004,0.00019750494,0.00003094238,0.000012809327,0.00020619335,0.00002113134,0.0000756127,0.998323,0.000109734065,0.000080121456,0.00056839094],"study_design_scores_gemma":[0.00010410748,0.00036668414,0.015525206,0.000031955853,0.00010661372,0.002802246,0.00020822277,0.0012435584,0.9758547,0.00020513187,0.0035103937,0.000041245003],"about_ca_topic_score_codex":0.0007650648,"about_ca_topic_score_gemma":0.0014688532,"teacher_disagreement_score":0.004028623,"about_ca_system_score_codex":0.0005720592,"about_ca_system_score_gemma":0.0003372755,"threshold_uncertainty_score":0.013477087},"labels":[],"label_agreement":null},{"id":"W4362592380","doi":"10.1158/1538-7445.am2023-1458","title":"Abstract 1458: The PAX5 transcription factor is a suppressor of NFAT-mediated breast cancer aggressivity","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Moncton","funders":"","keywords":"NFAT; Cancer research; Transcription factor; Breast cancer; Medicine; Biology; Cancer; Internal medicine; Gene; Biochemistry","score_opus":0.08277783532370771,"score_gpt":0.39741280694054026,"score_spread":0.31463497161683257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4362592380","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97835916,0.004987706,0.008998341,0.00042121796,0.00017191691,0.000054949047,0.001994193,0.0003400253,0.0046724332],"genre_scores_gemma":[0.9889726,0.0007008141,0.0017155912,0.00009243176,0.000020898235,0.000037243055,0.0018047234,0.000040385334,0.006615335],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998479,0.000024388739,0.0000153386,0.000035806243,0.000049103845,0.00002744695],"domain_scores_gemma":[0.9999306,0.000009104769,0.00002354626,0.0000071445547,0.000006662805,0.00002281714],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109378656,0.00044521352,0.00020495491,0.00027071135,0.0002216796,0.0002822802,0.00028645562,0.00030276002,0.004956946],"category_scores_gemma":[0.00007542573,0.00011979797,0.00027312365,0.0001666056,0.00023877404,0.00018039934,0.00023132311,0.0006416973,0.000940648],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007936515,0.000016135975,0.00014857709,0.00003876945,0.0000068904365,0.00005562287,0.0000058080095,0.000040934174,0.9982553,0.00020248402,0.00008856947,0.001061496],"study_design_scores_gemma":[0.000028776398,0.00017050664,0.0035128987,0.000009567433,0.000023065091,0.000546678,0.0000269282,0.0011829503,0.987007,0.00010257405,0.007384441,0.000004522457],"about_ca_topic_score_codex":0.000458373,"about_ca_topic_score_gemma":0.0005048328,"teacher_disagreement_score":0.004956946,"about_ca_system_score_codex":0.0003760099,"about_ca_system_score_gemma":0.00016224942,"threshold_uncertainty_score":0.016582608},"labels":[],"label_agreement":null},{"id":"W4367320450","doi":"10.1172/jci161453","title":"Pressure overload induces ISG15 to facilitate adverse ventricular remodeling and promote heart failure","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Jewish General Hospital; McGill University; Ted Rogers Centre for Heart Research; University Health Network; University of Toronto; Toronto General Hospital; St. Michael's Hospital","funders":"Biotechnology and Biological Sciences Research Council; Heart and Stroke Foundation of Canada; Banting and Best Diabetes Centre, University of Toronto; Canadian Institutes of Health Research; University of Toronto; Diabetes Canada","keywords":"Downregulation and upregulation; Ventricular remodeling; ISG15; Pressure overload; Heart failure; Inflammation; Internal medicine; Endocrinology; Cardiomyopathy; Cell biology; Filamin; Myocyte; Diabetic cardiomyopathy; Ubiquitin; Biology; Chemistry; Medicine; Cell; Biochemistry","score_opus":0.09130328682495234,"score_gpt":0.3491667649176099,"score_spread":0.2578634780926575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367320450","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9950363,0.0017885371,0.0016251312,0.00019599768,0.000051381518,0.000020521828,0.0001723701,0.000048856728,0.0010608917],"genre_scores_gemma":[0.99723685,0.00059895514,0.00080766925,0.00015707208,0.000017583714,0.000016718172,0.00019397089,0.000009808275,0.00096122065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989164,0.000019275314,0.0000084073445,0.000025274752,0.000024194926,0.000031178144],"domain_scores_gemma":[0.99992,0.0000057935,0.000031656804,0.000007767279,0.000006497651,0.00002815993],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016696054,0.00030684716,0.0001910573,0.00019221577,0.00013981047,0.00026717645,0.00012546989,0.00027604445,0.0012999072],"category_scores_gemma":[0.00007892536,0.00009947795,0.00027328855,0.00009248497,0.00028185532,0.00015031722,0.00025025022,0.00041721892,0.00020075767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002083719,0.00002578204,0.0016799205,0.000030447058,0.000012500549,0.00013104668,0.000012541076,0.00003073632,0.99632347,0.00011073114,0.000057371282,0.0013771071],"study_design_scores_gemma":[0.000109336856,0.0012406249,0.15839009,0.000055132597,0.000091062095,0.0016080999,0.00014745639,0.0013878276,0.8297629,0.0005949541,0.0065983078,0.0000142216095],"about_ca_topic_score_codex":0.00018661362,"about_ca_topic_score_gemma":0.00041378444,"teacher_disagreement_score":0.0012999072,"about_ca_system_score_codex":0.00021121006,"about_ca_system_score_gemma":0.00015998865,"threshold_uncertainty_score":0.0043486357},"labels":[],"label_agreement":null},{"id":"W4367674462","doi":"10.1055/s-0043-1768002","title":"iGlarLixi vs. Basal- plus kurzwirksames Insulin bei Erwachsenen mit Typ-2-Diabetes, die von einer Basalinsulin-Therapie intensiviert werden: Die SoliSimplify-Praxisstudie","year":2023,"lang":"de","type":"article","venue":"Diabetologie und Stoffwechsel","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Medicine; Gynecology; Psychology","score_opus":0.02523171663849914,"score_gpt":0.2844507738955225,"score_spread":0.2592190572570233,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4367674462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95665866,0.032544833,0.00107355,0.0013427024,0.00062910706,0.0007532384,0.0014849263,0.00012899877,0.0053840736],"genre_scores_gemma":[0.97827405,0.010905735,0.0022112962,0.0015736407,0.00034515923,0.0013075672,0.0019893004,0.000035676414,0.0033574267],"study_design_codex":"randomized_trial","study_design_gemma":"observational","domain_scores_codex":[0.9994349,0.00029228147,0.00005857185,0.000082399325,0.000061843144,0.00006996582],"domain_scores_gemma":[0.9992373,0.00031947298,0.00015428974,0.00007884092,0.00004790388,0.00016227852],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0018174569,0.00044498144,0.0013544519,0.00037106127,0.00016119452,0.00089459436,0.0003456606,0.00067185226,0.0056758015],"category_scores_gemma":[0.0017546946,0.0001959968,0.0011028034,0.00042673433,0.0003442762,0.000744717,0.00042704158,0.0019548396,0.00096032495],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.8601912,0.004982589,0.003065974,0.0012315623,0.0019087248,0.000038989503,0.00010801382,0.00068119954,0.004284376,0.0003497174,0.0018290272,0.1213286],"study_design_scores_gemma":[0.33342972,0.57088083,0.051598147,0.0012989356,0.009796021,0.00031677022,0.00054173934,0.0034087235,0.009472711,0.002200341,0.016948147,0.000107875145],"about_ca_topic_score_codex":0.0005981195,"about_ca_topic_score_gemma":0.0010253433,"teacher_disagreement_score":0.0056758015,"about_ca_system_score_codex":0.0004414088,"about_ca_system_score_gemma":0.00066801853,"threshold_uncertainty_score":0.018987417},"labels":[],"label_agreement":null},{"id":"W4375862671","doi":"10.1161/circresaha.122.322213","title":"Downregulation of FKBP5 Promotes Atrial Arrhythmogenesis","year":2023,"lang":"en","type":"article","venue":"Circulation Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"National Human Genome Research Institute; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; National Cancer Institute; National Institutes of Health; Nederlandse Organisatie voor Wetenschappelijk Onderzoek; European Commission; American Heart Association","keywords":"FKBP5; Gene knockdown; Transcription factor; Downregulation and upregulation; Medicine; Heat shock protein; Internal medicine; Endocrinology; Chemistry; Cardiology; Receptor; Glucocorticoid receptor; Biochemistry; Gene","score_opus":0.10271376080357424,"score_gpt":0.392591930469764,"score_spread":0.28987816966618973,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4375862671","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952598,0.0021209256,0.001503843,0.00010611887,0.000030209138,0.000009270397,0.00023768442,0.000055093657,0.0006770418],"genre_scores_gemma":[0.9981493,0.00047118746,0.00033840403,0.00003680638,0.000007111479,0.000011871521,0.00023602507,0.0000049857836,0.00074431737],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999044,0.000010952843,0.000013035359,0.000024345034,0.000020213483,0.00002701718],"domain_scores_gemma":[0.9998568,0.00002179619,0.000052947096,0.000011409986,0.000013119518,0.000043905107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011232811,0.00023142037,0.00018739585,0.00014265286,0.00017300603,0.00022320687,0.00009931312,0.00026905836,0.0015411085],"category_scores_gemma":[0.000108430526,0.00009163186,0.0001963874,0.00006992416,0.00017544688,0.000107907676,0.00017887013,0.00041200715,0.00042491866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012902281,0.000019153238,0.0006911421,0.000042830434,0.000008675877,0.00009410667,0.000010810615,0.00002894638,0.99800915,0.000046006167,0.000067841334,0.00085239275],"study_design_scores_gemma":[0.00007607495,0.0010680609,0.116428375,0.000043312484,0.00015556988,0.0020730272,0.000100925965,0.0022954186,0.8704621,0.00014411261,0.007138597,0.000014408369],"about_ca_topic_score_codex":0.0003772583,"about_ca_topic_score_gemma":0.000644094,"teacher_disagreement_score":0.0015411085,"about_ca_system_score_codex":0.00017848544,"about_ca_system_score_gemma":0.000092218295,"threshold_uncertainty_score":0.0051555037},"labels":[],"label_agreement":null},{"id":"W4375955901","doi":"10.7554/elife.84396","title":"Insights into cargo sorting by SNX32 and its role in neurite outgrowth","year":2023,"lang":"en","type":"article","venue":"eLife","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation","funders":"Science and Engineering Research Board; Department of Biotechnology, Ministry of Science and Technology, India; Indian Institute of Science","keywords":"Cell biology; Basigin; Neurite; Amphiphysin; Gene silencing; Transport protein; Biology; Sorting nexin; Immunoglobulin domain; HEK 293 cells; Mutant; Signal transducing adaptor protein; Receptor; Chemistry; Intracellular; Signal transduction; Endocytosis; Biochemistry; Endosome; Gene","score_opus":0.008623239105556952,"score_gpt":0.24635769939977883,"score_spread":0.23773446029422188,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4375955901","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948775,0.0021940763,0.0016896526,0.00015395299,0.000009563459,0.0000057109287,0.000094672476,0.000024418654,0.0009504858],"genre_scores_gemma":[0.9922502,0.002366424,0.0024017994,0.000046497353,0.0000050534454,0.000007871844,0.00024314497,0.000008103681,0.0026708697],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99996006,0.0000064361943,0.000002697094,0.0000071715526,0.0000136913195,0.000009893817],"domain_scores_gemma":[0.9999758,0.0000021444755,0.0000059938884,0.0000022058528,0.0000036439776,0.000010198826],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009148981,0.00039647805,0.00014236858,0.00014249868,0.0001395135,0.00017385816,0.0001390423,0.00025138422,0.00077082333],"category_scores_gemma":[0.00003917609,0.00007919625,0.00018714766,0.00006995951,0.00019018922,0.00025783034,0.00025677742,0.00035266363,0.00034300247],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000033142205,0.0000040458685,0.0002318756,0.000017302431,0.0000016791654,0.00009768898,0.000009104228,0.000059783426,0.99881625,0.00015758286,0.000008337508,0.00056324044],"study_design_scores_gemma":[0.00001623428,0.00022596217,0.01910289,0.000020274705,0.000018160094,0.0014602063,0.00014040337,0.0047074603,0.96714807,0.00061283866,0.006537825,0.000009626494],"about_ca_topic_score_codex":0.0007352641,"about_ca_topic_score_gemma":0.0009306002,"teacher_disagreement_score":0.00077082333,"about_ca_system_score_codex":0.0002758616,"about_ca_system_score_gemma":0.0002009095,"threshold_uncertainty_score":0.0025787354},"labels":[],"label_agreement":null},{"id":"W4377140274","doi":"10.1101/2023.05.19.541431","title":"Importin 13-dependent Axon Diameter Growth Regulates Conduction Speeds along Myelinated CNS Axons","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Wellcome Trust; Multiple Sclerosis Society; Lister Institute of Preventive Medicine; University of Edinburgh; Biotechnology and Biological Sciences Research Council; Multiple Sclerosis Society of Canada","keywords":"Axon; Nerve conduction velocity; Neuroscience; Growth cone; Nervous system; Soma; Biology; Anatomy; Biophysics","score_opus":0.02208972681382469,"score_gpt":0.23639290111207983,"score_spread":0.21430317429825516,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377140274","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97995526,0.00139256,0.013767228,0.0002704734,0.00005335398,0.000017681961,0.0008005604,0.00034190225,0.0034009463],"genre_scores_gemma":[0.986121,0.0007529295,0.0072228545,0.00007194215,0.000010322465,0.000033080214,0.00036303175,0.00024128266,0.0051834695],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998313,0.000012715257,0.000014003467,0.000047110636,0.000065427914,0.000029396997],"domain_scores_gemma":[0.9996511,0.000050773313,0.00013720866,0.00002749483,0.00006270169,0.000070851056],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023605794,0.00032499805,0.0002804328,0.00029239495,0.0002761529,0.00045904,0.00023672778,0.00032856234,0.0015982853],"category_scores_gemma":[0.00024720366,0.00024943554,0.00024013381,0.00014103309,0.00064978894,0.0003473521,0.00056855124,0.0008007147,0.00048498914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041945324,0.0000025966997,0.00020020956,0.00001767166,0.0000014884343,0.000017965207,0.000012868378,0.00010311155,0.9989505,0.00014129597,0.000041030904,0.00046940817],"study_design_scores_gemma":[0.000021662925,0.00006692209,0.014110498,0.000020601905,0.000014732635,0.00017913771,0.000052273634,0.0032519577,0.97957957,0.00029965866,0.0023870294,0.000015875163],"about_ca_topic_score_codex":0.002666574,"about_ca_topic_score_gemma":0.0031485506,"teacher_disagreement_score":0.002666574,"about_ca_system_score_codex":0.00083587045,"about_ca_system_score_gemma":0.0004928772,"threshold_uncertainty_score":0.0060646534},"labels":[],"label_agreement":null},{"id":"W4377823313","doi":"10.1101/2023.05.22.541727","title":"Development of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic strategy for Alzheimer’s disease","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute on Aging; Novartis Pharma; Genentech; Ontario Ministry of Economic Development and Innovation; Emory University; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ministero dello Sviluppo Economico; Genome Canada; Fundação de Amparo à Pesquisa do Estado de São Paulo; Diamond Light Source; Pfizer","keywords":"FERM domain; Radixin; Allosteric regulation; Moesin; Ezrin; Binding site; Cell biology; Plasma protein binding; Scaffold protein; Chemistry; Biology; Receptor; Biochemistry; Computational biology; Membrane protein; Integral membrane protein; Signal transduction; Cytoskeleton; Cell","score_opus":0.036928744889459846,"score_gpt":0.2782765314652557,"score_spread":0.24134778657579586,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4377823313","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9683784,0.011688967,0.011863223,0.00057513575,0.000129086,0.0006041102,0.00061402743,0.00024925132,0.0058977813],"genre_scores_gemma":[0.9781773,0.006744973,0.009903519,0.00027001332,0.000033380227,0.00021655414,0.0007237041,0.000014699863,0.003915919],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993813,0.00001167775,0.0000038167573,0.000008736861,0.000017192115,0.000020484693],"domain_scores_gemma":[0.99996185,0.000005620926,0.000010106451,0.000002532086,0.000006930526,0.000012955499],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00023065115,0.00051466096,0.00041504347,0.00032186892,0.00015685354,0.0002517915,0.00038967462,0.00035912104,0.0013316111],"category_scores_gemma":[0.000095277624,0.00017165272,0.00041717634,0.00017613107,0.0001617909,0.00020982148,0.0002016551,0.00066007336,0.00031920723],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005383118,0.0007193473,0.00037016722,0.00019279367,0.000062197796,0.0002903963,0.000032337386,0.0018197102,0.96960706,0.0008315163,0.0005140733,0.025022063],"study_design_scores_gemma":[0.0015141761,0.012988381,0.004962373,0.00006294704,0.00024151106,0.0011826619,0.00005239367,0.009417196,0.9417228,0.0004595737,0.027349656,0.000046400157],"about_ca_topic_score_codex":0.00042318588,"about_ca_topic_score_gemma":0.0010725519,"teacher_disagreement_score":0.0013316111,"about_ca_system_score_codex":0.00031954917,"about_ca_system_score_gemma":0.00024788338,"threshold_uncertainty_score":0.0044546127},"labels":[],"label_agreement":null},{"id":"W4378648979","doi":"10.1152/physiol.2023.38.s1.5735185","title":"Loss of A Metalloproteinase and Disintegrin 15 leads to exacerbated myocardial hypertrophy and dilation through activation of the calcineurin pathway in male but not female micev","year":2023,"lang":"en","type":"article","venue":"Physiology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Internal medicine; Endocrinology; Muscle hypertrophy; Calcineurin; Biology; Pressure overload; Cardiomyopathy; Disintegrin; Metalloproteinase; Matrix metalloproteinase; Medicine; Heart failure; Cardiac hypertrophy; Transplantation","score_opus":0.019517453870640578,"score_gpt":0.25579703938124315,"score_spread":0.23627958551060257,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4378648979","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914249,0.0013053346,0.0028403618,0.00035816955,0.00013690679,0.00006494312,0.0017248271,0.00030599485,0.0018384781],"genre_scores_gemma":[0.9765223,0.0018237529,0.0032251119,0.00031749188,0.00007310891,0.00023339361,0.0020293917,0.0001993652,0.015576122],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99938595,0.000082855775,0.000075402786,0.0001865847,0.00012403537,0.00014509629],"domain_scores_gemma":[0.99942374,0.000037534504,0.00021958914,0.00004487706,0.00002254594,0.00025172177],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003770503,0.0011600566,0.00057900656,0.0013389336,0.0003498756,0.00050541223,0.00057776726,0.0011461764,0.0042812545],"category_scores_gemma":[0.00016735407,0.00071964687,0.0009275692,0.00034476657,0.0006602297,0.0005843193,0.00046545168,0.0017545744,0.0010917136],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00052070833,0.0001972711,0.0003983992,0.0000448526,0.000017876522,0.00029787305,0.00004268419,0.000038257815,0.9973465,0.00013569692,0.00010671786,0.0008530178],"study_design_scores_gemma":[0.0002500189,0.0043831817,0.046262152,0.00007294028,0.00013523469,0.0036116773,0.0002529675,0.0012207798,0.9389258,0.00027881705,0.00456168,0.000044800152],"about_ca_topic_score_codex":0.00061632803,"about_ca_topic_score_gemma":0.0009084321,"teacher_disagreement_score":0.0042812545,"about_ca_system_score_codex":0.0003875986,"about_ca_system_score_gemma":0.00024898647,"threshold_uncertainty_score":0.014322221},"labels":[],"label_agreement":null},{"id":"W4380836514","doi":"10.1161/circ.146.suppl_1.15505","title":"Abstract 15505: Cardiac-Specific Jarid2 Deficiency, Results in Improved Survival and Myocardial Function Following Experimental Sepsis","year":2022,"lang":"en","type":"article","venue":"Circulation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Medicine; Sepsis; Ejection fraction; Tumor necrosis factor alpha; Internal medicine; Cardiac function curve; Heart failure; Cardiology; Peritonitis; Lipopolysaccharide binding protein; Endocrinology; Inflammation; Gastroenterology; Acute-phase protein","score_opus":0.017861546797411768,"score_gpt":0.24840324157082125,"score_spread":0.23054169477340947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4380836514","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99028987,0.0019473452,0.002450704,0.00041646714,0.00017879816,0.000115829156,0.0027443785,0.00032325287,0.0015333074],"genre_scores_gemma":[0.9784062,0.0015885112,0.005765727,0.0005307023,0.00008968919,0.0003860787,0.0036828523,0.00016292396,0.009387307],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9996654,0.000043419066,0.00006503997,0.0000890272,0.00007153987,0.00006557039],"domain_scores_gemma":[0.99957985,0.000027260821,0.0001445315,0.000022955428,0.00001835897,0.00020704798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002973058,0.00090983754,0.0007019276,0.00052527484,0.00034691443,0.0005662218,0.00047496991,0.00072496635,0.0047221417],"category_scores_gemma":[0.0002164881,0.00042897652,0.00034334764,0.00022038582,0.00075492816,0.0004144206,0.00036980832,0.0010889487,0.0012486309],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011833804,0.0002519336,0.00027988476,0.00015362547,0.000017731705,0.0002102274,0.000034582168,0.00004481082,0.99624264,0.00010013079,0.00025342865,0.0012276566],"study_design_scores_gemma":[0.0010116736,0.0055745253,0.02423612,0.00012338703,0.00018632149,0.0032125881,0.00028467967,0.0016856148,0.95418805,0.00021025483,0.009239244,0.000047456473],"about_ca_topic_score_codex":0.0004154199,"about_ca_topic_score_gemma":0.00075786334,"teacher_disagreement_score":0.0047221417,"about_ca_system_score_codex":0.00040258115,"about_ca_system_score_gemma":0.0003982869,"threshold_uncertainty_score":0.015797138},"labels":[],"label_agreement":null},{"id":"W4383340407","doi":"10.1371/journal.ppat.1011445","title":"Calcineurin: The Achilles’ heel of fungal pathogens","year":2023,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases; National Institute of Allergy and Infectious Diseases; Center for AIDS Research, University of Washington; National Institutes of Health; University of Arkansas for Medical Sciences; Canadian Institute for Advanced Research; Center for AIDS Research, Duke University; Clemson University","keywords":"Heel; Calcineurin; Medicine; Microbiology; Biology; Internal medicine; Anatomy; Transplantation","score_opus":0.02459790459203198,"score_gpt":0.25341707659047713,"score_spread":0.22881917199844515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4383340407","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.04481309,0.63832825,0.018681673,0.2652919,0.014679808,0.00004634499,0.0005654376,0.0008325039,0.016760994],"genre_scores_gemma":[0.3722502,0.5477434,0.009619055,0.028391756,0.017730068,0.00006848777,0.00029592964,0.00016906648,0.023731994],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99913836,0.00017393152,0.00004887844,0.000137973,0.00033171757,0.00016912643],"domain_scores_gemma":[0.9979517,0.0006878219,0.00018874828,0.00017721557,0.00041392114,0.0005805723],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002609234,0.00091410574,0.0016478013,0.0010498286,0.0014008217,0.005298242,0.0011227588,0.0041399263,0.004115869],"category_scores_gemma":[0.0024233183,0.00041343903,0.0004369721,0.0007657887,0.0054738675,0.007898483,0.0023392376,0.008032249,0.0014443368],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002083423,0.0001827437,0.003907337,0.0035562085,0.00028096145,0.003897118,0.0015796918,0.0024690053,0.12572911,0.38801706,0.119560264,0.34873718],"study_design_scores_gemma":[0.00019549443,0.0004923568,0.004264686,0.0013736204,0.00011348921,0.0035899624,0.0031075126,0.0026276275,0.027194925,0.26514775,0.6917202,0.0001724558],"about_ca_topic_score_codex":0.001179933,"about_ca_topic_score_gemma":0.0015827948,"teacher_disagreement_score":0.005298242,"about_ca_system_score_codex":0.0014641365,"about_ca_system_score_gemma":0.002781802,"threshold_uncertainty_score":0.013799131},"labels":[],"label_agreement":null},{"id":"W4385068009","doi":"10.1101/2023.07.20.549884","title":"Induction of antiviral gene expression by cyclosporine A, but not inhibition of cyclophilin A or B, contributes to its restriction of human coronavirus 229E infection in a lung epithelial cell line","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"J.P. Bickell Foundation; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Queen's University; Fondation pour la Recherche Médicale; Banting Research Foundation","keywords":"Antiviral drug; Interferon; Biology; Immune system; Immunology; Virology; Cyclophilin; Virus; Innate immune system; Drug; Gene; Pharmacology; Genetics","score_opus":0.024013688286845435,"score_gpt":0.26739148068806773,"score_spread":0.2433777924012223,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385068009","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99345183,0.0011860625,0.0023813797,0.00012807564,0.00004017017,0.00004066656,0.00069942494,0.00006451702,0.0020077962],"genre_scores_gemma":[0.9938471,0.0007405451,0.0019256012,0.000067773304,0.000016696558,0.000050762083,0.001095534,0.000014308821,0.0022416494],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99985015,0.000026013884,0.000022185803,0.000026012396,0.000042975586,0.00003254881],"domain_scores_gemma":[0.9998791,0.00003606914,0.000015996673,0.000028093142,0.000016728913,0.000024025167],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000115965886,0.0001740388,0.00023199964,0.00016446983,0.00015694374,0.0002834755,0.00010959477,0.00018698123,0.0014258098],"category_scores_gemma":[0.000086175016,0.000090020425,0.00030026346,0.00015949422,0.0001611017,0.00010373931,0.00011259384,0.00045302438,0.00038433238],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000041589064,0.000026999931,0.00014283058,0.000016393004,0.0000029046737,0.000022567247,0.0000065777917,0.000025910143,0.9992945,0.000034376633,0.000026814609,0.0003586402],"study_design_scores_gemma":[0.000013906252,0.00031048848,0.0068006134,0.000003945564,0.000011395473,0.00015818852,0.000038314018,0.0012461366,0.9894288,0.000020865466,0.0019641796,0.0000031165464],"about_ca_topic_score_codex":0.00083097693,"about_ca_topic_score_gemma":0.0008933047,"teacher_disagreement_score":0.0014258098,"about_ca_system_score_codex":0.00017829392,"about_ca_system_score_gemma":0.00020934986,"threshold_uncertainty_score":0.004769802},"labels":[],"label_agreement":null},{"id":"W4385253493","doi":"10.7554/elife.83868.sa0","title":"Editor's evaluation: Conformational regulation and target-myristoyl switch of calcineurin B homologous protein 3","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Myristoylation; Effector; Calcineurin; Chemistry; Protein superfamily; Biophysics; Biochemistry; Cell biology; Membrane; Biology; Medicine","score_opus":0.024901266114938682,"score_gpt":0.3119915369889842,"score_spread":0.2870902708740455,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385253493","genre_codex":"editorial","genre_gemma":"other","domain_codex":null,"domain_gemma":"evaluation","model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":"evaluation","domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029470996,0.0038160025,0.00052015204,0.0865166,0.90435374,0.000074708885,0.00015925147,0.00014107661,0.0041238028],"genre_scores_gemma":[0.0057631447,0.008509383,0.0009979939,0.047451142,0.8617013,0.00011382485,0.00021585787,0.00021280578,0.07503445],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9945545,0.00080735993,0.00065149274,0.0005628057,0.0028976519,0.0005261543],"domain_scores_gemma":[0.956842,0.00599693,0.0020003456,0.00097492826,0.028147832,0.0060379673],"candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.007548213,0.00143152,0.001896002,0.001979257,0.0017673259,0.004361976,0.003251862,0.0077101383,0.043992475],"category_scores_gemma":[0.0334477,0.00056960405,0.0010599247,0.0009749319,0.0012292215,0.0019613898,0.0013304644,0.0050077937,0.02246696],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00005178559,0.000014664204,0.00009258353,0.00026281242,0.000015606956,0.00026806063,0.000012492009,0.00005231758,0.00017095612,0.00031603276,0.9852846,0.013458127],"study_design_scores_gemma":[0.0000632956,0.000035537523,0.00063893566,0.00027075064,0.000032797605,0.0006403924,0.000053815653,0.00045060454,0.0005783568,0.00052715983,0.9966833,0.000024972458],"about_ca_topic_score_codex":0.001355705,"about_ca_topic_score_gemma":0.003744501,"teacher_disagreement_score":0.9924518,"about_ca_system_score_codex":0.0021263317,"about_ca_system_score_gemma":0.0042862315,"threshold_uncertainty_score":0.14716953},"labels":[],"label_agreement":null},{"id":"W4385605642","doi":"10.1101/2023.07.28.23293350","title":"Assessing the role of rare pathogenic variants in heart failure progression by exome sequencing in 8,089 patients","year":2023,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Regeneron Pharmaceuticals; Canada Research Chairs; AstraZeneca; Alnylam Pharmaceuticals; Pfizer; Biogen; Université de Montréal; Bristol-Myers Squibb","keywords":"Biobank; Exome; Heart failure; Exome sequencing; Medicine; Disease; Candidate gene; Population; Bioinformatics; Internal medicine; Gene; Genetics; Biology; Mutation","score_opus":0.020706025657650916,"score_gpt":0.2953388414029474,"score_spread":0.2746328157452965,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385605642","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99515593,0.0003100352,0.00066867884,0.00013047137,0.000012307432,0.000012228507,0.0032396822,0.000013879277,0.00045680653],"genre_scores_gemma":[0.99454826,0.00011931208,0.0008149909,0.000118420394,0.000017113198,0.000026935371,0.0038656471,0.000014453755,0.00047490626],"study_design_codex":"observational","study_design_gemma":"observational","domain_scores_codex":[0.99965346,0.00007313542,0.00003675012,0.00014684245,0.000045736786,0.00004408778],"domain_scores_gemma":[0.99938166,0.0003076445,0.00012411542,0.000075206255,0.00004734712,0.00006406816],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00066360214,0.00029966002,0.0003984202,0.0004253533,0.00044860505,0.0006362121,0.00024125304,0.0005066837,0.002838602],"category_scores_gemma":[0.0020878967,0.00015322218,0.00034145662,0.00047875318,0.00024182392,0.000289288,0.0004911684,0.00048704655,0.0003853148],"study_design_candidate":"observational","study_design_consensus":"observational","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.002568925,0.00010520464,0.95607406,0.00011311466,0.00033670073,0.0028192378,0.00033863742,0.0011389593,0.0177569,0.00045769295,0.0026150933,0.015675567],"study_design_scores_gemma":[0.0003230687,0.00040285848,0.98008037,0.00006148364,0.0003106394,0.004979511,0.00030227142,0.002661742,0.0036842881,0.0014819312,0.005678377,0.00003345327],"about_ca_topic_score_codex":0.0009170714,"about_ca_topic_score_gemma":0.0010166038,"teacher_disagreement_score":0.002838602,"about_ca_system_score_codex":0.00016422241,"about_ca_system_score_gemma":0.00014263627,"threshold_uncertainty_score":0.009496093},"labels":[],"label_agreement":null},{"id":"W4385663970","doi":"10.12688/f1000research.130126.2","title":"Identification of high-performing antibodies for Moesin for use in Western Blot, immunoprecipitation, and immunofluorescence","year":2023,"lang":"en","type":"preprint","venue":"F1000Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Mitacs; National Institutes of Health; Ontario Genomics; Genome Canada","keywords":"Moesin; Western blot; Immunoprecipitation; Immunofluorescence; Antibody; Cytoskeleton; Cell biology; Blot; Actin cytoskeleton; Radixin; Biology; Ezrin; Molecular biology; Virology; Immunology; Cell; Genetics; Gene","score_opus":0.06620591571009488,"score_gpt":0.3621808207981537,"score_spread":0.29597490508805885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4385663970","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.21456721,0.010891086,0.6796587,0.0030582014,0.002015493,0.005396638,0.03267361,0.0108655235,0.040873595],"genre_scores_gemma":[0.11224685,0.0071545267,0.7428383,0.0010720834,0.00028870368,0.0066763405,0.0828073,0.006319735,0.04059616],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99767536,0.00035706797,0.00043685592,0.00040631686,0.0007818764,0.00034257886],"domain_scores_gemma":[0.99764675,0.00041305952,0.00020070233,0.00047652802,0.0010652529,0.00019760449],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0034075335,0.0028436724,0.0014756486,0.0028843815,0.0015127164,0.0014331964,0.0017000344,0.0014175329,0.017499119],"category_scores_gemma":[0.0034727908,0.0014016371,0.0011408797,0.0017038479,0.00070155767,0.0010807476,0.0012869034,0.0027834955,0.022032809],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001606963,0.000071203765,0.00031974615,0.00037556456,0.000025919515,0.000118735596,0.000106216394,0.00009517428,0.98447776,0.00086908386,0.0048023625,0.008577529],"study_design_scores_gemma":[0.00006767146,0.00015483933,0.0048488644,0.00014730133,0.000088577195,0.0008567787,0.00008789224,0.0013453388,0.87629956,0.00049607025,0.11555997,0.000047061345],"about_ca_topic_score_codex":0.0013910711,"about_ca_topic_score_gemma":0.0039187544,"teacher_disagreement_score":0.017499119,"about_ca_system_score_codex":0.001410282,"about_ca_system_score_gemma":0.0010796876,"threshold_uncertainty_score":0.058540404},"labels":[],"label_agreement":null},{"id":"W4386209304","doi":"10.1111/jnc.15909","title":"Function and regulation of <i>cis</i> P‐tau in the pathogenesis and treatment of conventional and nonconventional tauopathies","year":2023,"lang":"en","type":"review","venue":"Journal of Neurochemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"National Cancer Institute; National Institute on Aging; National Institutes of Health; Canada Foundation for Innovation","keywords":"Tauopathy; Progressive supranuclear palsy; Corticobasal degeneration; Tau protein; Frontotemporal dementia; Synucleinopathies; Frontotemporal lobar degeneration; Chronic traumatic encephalopathy; Neuroscience; PIN1; Hyperphosphorylation; Neurodegeneration; Alzheimer's disease; Medicine; Disease; Biology; Dementia; Biochemistry; Internal medicine; Phosphorylation; Parkinson's disease; Isomerase; Alpha-synuclein","score_opus":0.0437034697444249,"score_gpt":0.30266945448692795,"score_spread":0.25896598474250304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386209304","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.20059712,0.7699505,0.010180428,0.0034509087,0.0014162926,0.0002563947,0.00038315813,0.00040526545,0.01335995],"genre_scores_gemma":[0.684255,0.29542205,0.0091266185,0.0020929764,0.0012362141,0.00038498425,0.00079451856,0.00008520409,0.0066023753],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9997886,0.000049701797,0.000024297498,0.000037670834,0.000057520654,0.000042185955],"domain_scores_gemma":[0.9998981,0.000011467674,0.000027540102,0.0000071713816,0.000031268242,0.000024558294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005489774,0.0003974832,0.0005610812,0.00053368823,0.00023218353,0.00069584197,0.00071395043,0.00061167195,0.0011198545],"category_scores_gemma":[0.00032012182,0.00012291779,0.0006504361,0.00029443792,0.0004004868,0.00047268544,0.00038569755,0.0014636284,0.0004961142],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0039292923,0.0026737002,0.0020294904,0.0046467506,0.00038575433,0.0012234066,0.00028068692,0.0017624357,0.31763685,0.007802271,0.013293686,0.64433575],"study_design_scores_gemma":[0.0031869935,0.02068306,0.029378979,0.0019158495,0.001631504,0.008558063,0.00044431363,0.0081683025,0.35013187,0.012066231,0.5636078,0.00022700019],"about_ca_topic_score_codex":0.00046247066,"about_ca_topic_score_gemma":0.0008356463,"teacher_disagreement_score":0.0011198545,"about_ca_system_score_codex":0.0003670585,"about_ca_system_score_gemma":0.00036785792,"threshold_uncertainty_score":0.0037462711},"labels":[],"label_agreement":null},{"id":"W4386531943","doi":"10.5194/amt-2023-99-ac1","title":"Reply to CC1","year":2023,"lang":"ceb","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Environment and Climate Change Canada","funders":"National Oceanic and Atmospheric Administration; Commonwealth Scientific and Industrial Research Organisation","keywords":"Arctic; Observatory; Physics; Atmospheric research; Greenhouse gas; Meteorology; Environmental science; Atmospheric sciences; Astrophysics; Geology","score_opus":0.034862644131896124,"score_gpt":0.3276939473819296,"score_spread":0.2928313032500335,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4386531943","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00022142631,0.0009448846,0.0002508663,0.7484705,0.22430767,0.00012348394,0.0007326512,0.0004722022,0.02447637],"genre_scores_gemma":[0.0022814053,0.00055369246,0.00025511556,0.85560095,0.05741714,0.0002402479,0.0002931538,0.0002836847,0.08307459],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.995854,0.00071288354,0.00040907797,0.00072900724,0.0015302866,0.00076482113],"domain_scores_gemma":[0.9873065,0.0035142493,0.0004239024,0.0007857358,0.005840076,0.0021295238],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.004354145,0.0011487325,0.0013228467,0.0013969756,0.0042940737,0.00618654,0.0032203957,0.031032816,0.16252586],"category_scores_gemma":[0.03920117,0.0006950257,0.0015870285,0.0013437913,0.0026877502,0.0038740365,0.0031022986,0.02408191,0.114812784],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007972098,0.000003078669,0.00003205398,0.000014251336,0.0000013125722,0.000033549797,0.000010356842,0.0000040813397,0.000016170256,0.00023635812,0.9981822,0.0014586572],"study_design_scores_gemma":[0.00001542848,0.000010541135,0.00024575664,0.000063680774,0.000003284694,0.00007647095,0.00008041955,0.000038146005,0.00006878012,0.00058684364,0.9987943,0.000016352657],"about_ca_topic_score_codex":0.009058751,"about_ca_topic_score_gemma":0.00903594,"teacher_disagreement_score":0.8374741,"about_ca_system_score_codex":0.0058356794,"about_ca_system_score_gemma":0.006689815,"threshold_uncertainty_score":0.5437032},"labels":[],"label_agreement":null},{"id":"W4387240739","doi":"10.5281/zenodo.4818440","title":"Antibody Characterization Report for Sequestosome-1","year":2021,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Montreal Neurological Institute and Hospital","funders":"","keywords":"Sequestosome 1; Antibody; Characterization (materials science); Immunology; Medicine; Materials science; Nanotechnology","score_opus":0.028410526210892708,"score_gpt":0.27982002736738326,"score_spread":0.2514095011564906,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387240739","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.14263996,0.026780743,0.62712777,0.003967746,0.0042412705,0.009645646,0.109706596,0.0077901105,0.068100125],"genre_scores_gemma":[0.124772675,0.021847738,0.26698187,0.00218527,0.00093051465,0.009040899,0.46862638,0.003378754,0.10223588],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99835795,0.00019786025,0.00021103772,0.0003590422,0.0006014142,0.0002727762],"domain_scores_gemma":[0.997985,0.00029878804,0.00012209585,0.00040853818,0.000926393,0.0002591886],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014241678,0.0018559191,0.0011781186,0.0023888517,0.0015266751,0.0012300899,0.0015329695,0.001166913,0.026316252],"category_scores_gemma":[0.0028831172,0.0009935404,0.0009969795,0.0015887341,0.00040352,0.00091139285,0.0010800703,0.0026852626,0.046116307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00032510574,0.00016518359,0.00059226993,0.0008885431,0.00008127183,0.00032644058,0.0001935667,0.00024096333,0.94585794,0.0016772941,0.026253114,0.023398247],"study_design_scores_gemma":[0.000110614295,0.0003986293,0.0030573308,0.00018646965,0.00013574892,0.002289048,0.000090248395,0.0011932647,0.44422203,0.0006944438,0.54754823,0.0000740274],"about_ca_topic_score_codex":0.0013281438,"about_ca_topic_score_gemma":0.002279067,"teacher_disagreement_score":0.026316252,"about_ca_system_score_codex":0.00067637925,"about_ca_system_score_gemma":0.0014318464,"threshold_uncertainty_score":0.08803666},"labels":[],"label_agreement":null},{"id":"W4387358847","doi":"10.1016/j.antiviral.2023.105730","title":"Induction of antiviral gene expression by cyclosporine A, but not inhibition of cyclophilin A or B, contributes to its restriction of human coronavirus 229E infection in a lung epithelial cell line","year":2023,"lang":"en","type":"article","venue":"Antiviral Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Queen's University; Banting Research Foundation","keywords":"Cyclophilin A; Biology; Virology; Gene; Coronavirus; Cell culture; Cyclophilin; Gene expression; Cell biology; Coronavirus disease 2019 (COVID-19); Molecular biology; Genetics; Medicine; Pathology","score_opus":0.06718686528676804,"score_gpt":0.38283595623790806,"score_spread":0.31564909095114,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387358847","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9949222,0.00081292854,0.0018048651,0.00012954812,0.00004420644,0.000026882306,0.0004670558,0.000085899264,0.0017064066],"genre_scores_gemma":[0.9943984,0.0005566726,0.0017970988,0.000053593645,0.000020092177,0.000038228995,0.0010122356,0.00003553523,0.0020882061],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997303,0.000048264832,0.000030913892,0.000038911803,0.00006728302,0.00008427303],"domain_scores_gemma":[0.99955267,0.0001674614,0.00004395513,0.00010527688,0.000036099238,0.00009448422],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022377603,0.00031522737,0.0004800336,0.00038010298,0.00032288962,0.00051028415,0.00020678573,0.00030567017,0.0011756602],"category_scores_gemma":[0.00019447684,0.00020320404,0.00050399976,0.00037057398,0.00034342555,0.00021194597,0.00023091256,0.0010520368,0.00046694197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007023622,0.00003694647,0.0000915488,0.000009563477,0.000002208177,0.000025938945,0.0000116861265,0.000026985075,0.9994155,0.00006338993,0.000018113364,0.00022776728],"study_design_scores_gemma":[0.000013992099,0.0002286063,0.0032584583,0.0000026128955,0.000009151632,0.0001314344,0.000027718708,0.00071824767,0.9946353,0.000025655718,0.00094572455,0.0000030943559],"about_ca_topic_score_codex":0.0013797205,"about_ca_topic_score_gemma":0.0017525193,"teacher_disagreement_score":0.0013797205,"about_ca_system_score_codex":0.00034162367,"about_ca_system_score_gemma":0.00041510558,"threshold_uncertainty_score":0.0039330125},"labels":[],"label_agreement":null},{"id":"W4387866053","doi":"10.1111/jipb.13577","title":"Epigenetic regulation of <i>N</i>‐hydroxypipecolic acid biosynthesis by the AIPP3‐PHD2‐CPL2 complex","year":2023,"lang":"en","type":"article","venue":"Journal of Integrative Plant Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Epigenetics; Mutant; Gene; Biosynthesis; Biology; Histone; Psychological repression; Genetics; Regulation of gene expression; Gene expression; Cell biology; Biochemistry","score_opus":0.02101767796807798,"score_gpt":0.27039360048451877,"score_spread":0.24937592251644078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4387866053","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9825848,0.0011290173,0.011573873,0.00029391432,0.000053639265,0.000028122593,0.00080586143,0.00029281672,0.003238027],"genre_scores_gemma":[0.9957884,0.00016570762,0.001390983,0.000069742135,0.000008746792,0.000016577866,0.00052489294,0.00003914896,0.001995747],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999019,0.00000904991,0.0000049651408,0.00004071825,0.000022654258,0.0000206232],"domain_scores_gemma":[0.9998982,0.000011763775,0.000030891373,0.000013958548,0.000013645671,0.00003165303],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000112498754,0.00025813485,0.00018132679,0.00011045751,0.00021099085,0.0004261459,0.00027544162,0.00022489509,0.0012226001],"category_scores_gemma":[0.00013413986,0.000119329394,0.00022704921,0.00008656616,0.0003229601,0.000273244,0.00044310524,0.00048251683,0.00046004663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000048863272,0.000005598765,0.00034332642,0.000013323538,0.0000025495,0.000032735465,0.000007513713,0.000036412424,0.9985569,0.00012587153,0.000046681143,0.00078037323],"study_design_scores_gemma":[0.000020107918,0.00004455376,0.019153118,0.0000029456394,0.000009251702,0.00017985962,0.000028362012,0.0023673645,0.9756295,0.00017547917,0.002380643,0.000008723572],"about_ca_topic_score_codex":0.0008232747,"about_ca_topic_score_gemma":0.0012396319,"teacher_disagreement_score":0.0012226001,"about_ca_system_score_codex":0.0005175849,"about_ca_system_score_gemma":0.00022558858,"threshold_uncertainty_score":0.004090011},"labels":[],"label_agreement":null},{"id":"W4388817915","doi":"10.1016/j.bbrc.2023.149253","title":"An ex vivo screening using mouse brain mitochondria identified seco-cycline D as an inhibitor of mitochondrial permeability transition pore","year":2023,"lang":"en","type":"article","venue":"Biochemical and Biophysical Research Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"RIKEN; Centre for Studies in Religion and Society, University of Victoria; Japan Agency for Medical Research and Development","keywords":"MPTP; Mitochondrial permeability transition pore; Mitochondrion; Ex vivo; Pharmacology; In vivo; Chemistry; Cyclophilin; Biochemistry; Biology; Endocrinology; In vitro; Apoptosis; Programmed cell death; Gene; Dopamine; Genetics","score_opus":0.08778613756474919,"score_gpt":0.4076794707325479,"score_spread":0.3198933331677987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4388817915","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.967196,0.0037581252,0.0218935,0.0004743763,0.000119102886,0.0001730674,0.002916185,0.00026736528,0.003202297],"genre_scores_gemma":[0.9829898,0.0019360977,0.008592094,0.00010542399,0.000013979221,0.00006637477,0.0026147654,0.000046317884,0.0036350368],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99989283,0.000016794362,0.0000121987505,0.000028461194,0.000029224126,0.000020498264],"domain_scores_gemma":[0.99987864,0.000042394404,0.000025762893,0.000012637616,0.000016871258,0.00002357917],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024018671,0.00044440577,0.00034518787,0.0002851257,0.00022225102,0.00038219374,0.0002573507,0.00028489417,0.001296216],"category_scores_gemma":[0.00018368172,0.0001433599,0.00030018447,0.0002111591,0.00020658571,0.0001911342,0.00014205994,0.0004885477,0.000417905],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009326366,0.000024060811,0.00016825572,0.00002097847,0.0000069535577,0.000059551483,0.0000054788115,0.00006181494,0.9988323,0.000107237036,0.00004654987,0.0005736152],"study_design_scores_gemma":[0.00001171037,0.00008959547,0.00044208576,0.0000010449269,0.000010008552,0.00012675166,0.0000071515615,0.00036120857,0.99737996,0.00001495136,0.0015537988,0.0000017433504],"about_ca_topic_score_codex":0.0008163856,"about_ca_topic_score_gemma":0.0011328906,"teacher_disagreement_score":0.001296216,"about_ca_system_score_codex":0.00050240516,"about_ca_system_score_gemma":0.00029548712,"threshold_uncertainty_score":0.0043362975},"labels":[],"label_agreement":null},{"id":"W4389020140","doi":"10.1096/fasebj.31.1_supplement.846.1","title":"Troponin degradation products: more specific marker for myocardial infarction","year":2017,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"Medicine; Myocardial infarction; Troponin I; Cardiology; Troponin; Ischemia; Internal medicine; Proteases; Biochemistry; Chemistry; Enzyme","score_opus":0.024687813842614308,"score_gpt":0.27388311950067734,"score_spread":0.24919530565806303,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389020140","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8212782,0.11983128,0.034734014,0.0015713999,0.0020510992,0.0003803546,0.0031258294,0.00080539123,0.016222399],"genre_scores_gemma":[0.93856984,0.010404031,0.037262727,0.002189699,0.0013030706,0.000414812,0.0024073727,0.00008820612,0.007360275],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9985954,0.00028292168,0.00014936205,0.00051421614,0.00035534383,0.000102692546],"domain_scores_gemma":[0.99894804,0.00024628465,0.0004478754,0.000062624975,0.00017893528,0.00011621675],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014743508,0.0009710745,0.0006497335,0.0016218812,0.00018062636,0.0006124606,0.0004500105,0.0008812169,0.0036007022],"category_scores_gemma":[0.0016289861,0.00017922933,0.00030122514,0.0010520768,0.00038737254,0.0005006954,0.00032793707,0.0010262287,0.001642503],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021148988,0.00046728455,0.3917818,0.0016494805,0.00033110924,0.0016931789,0.00050609227,0.00061389874,0.46314156,0.0013576113,0.006348906,0.1299942],"study_design_scores_gemma":[0.00018423448,0.0041111074,0.74432725,0.0005647369,0.00043601962,0.03158876,0.00034508374,0.003835983,0.15796182,0.0030985223,0.053420193,0.00012633532],"about_ca_topic_score_codex":0.00021148048,"about_ca_topic_score_gemma":0.00024727106,"teacher_disagreement_score":0.0036007022,"about_ca_system_score_codex":0.00030011951,"about_ca_system_score_gemma":0.00013673118,"threshold_uncertainty_score":0.012045622},"labels":[],"label_agreement":null},{"id":"W4389026643","doi":"10.1096/fasebj.30.1_supplement.226.4","title":"Cyclophilin A is Crucial for <i>Listeria</i> and <i>Salmonella</i> Invasion and Cell‐to‐Cell Spreading","year":2016,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Cypa; Cell biology; Membrane ruffling; Cyclophilin A; Actin; Biology; Listeria monocytogenes; Cytoplasm; Listeria; Actin cytoskeleton; Motility; Cell; Cytoskeleton; Bacteria; Biochemistry; Molecular biology; Genetics","score_opus":0.014141921328287423,"score_gpt":0.2347582509925641,"score_spread":0.22061632966427666,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389026643","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99098784,0.0027307563,0.002229262,0.00030625516,0.00006868129,0.000021746097,0.0007424176,0.0001863845,0.002726706],"genre_scores_gemma":[0.9956136,0.00051657774,0.00087959744,0.000118110635,0.000016251732,0.000018657684,0.00083318166,0.000024958528,0.0019790432],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998394,0.000024616176,0.000013437938,0.000039966857,0.00004162738,0.000040871008],"domain_scores_gemma":[0.9997527,0.00002554366,0.00008252226,0.000022591035,0.000024035924,0.00009255798],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008084489,0.00032762645,0.00014290254,0.00019883874,0.00027159395,0.0003414913,0.00017221272,0.00042619652,0.0018289638],"category_scores_gemma":[0.00014244368,0.00016685232,0.00036193544,0.000097780365,0.00022879249,0.00016975566,0.0002603805,0.0005158234,0.00070510816],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009752307,0.000012646923,0.0003678026,0.000023445547,0.0000045984575,0.00010392391,0.000006349576,0.000022025872,0.9985997,0.00009412043,0.000103259925,0.0005646501],"study_design_scores_gemma":[0.000029273042,0.00017257157,0.06597193,0.000013868029,0.000027127617,0.0014041509,0.00006571526,0.0014013629,0.92499983,0.00013556024,0.005767096,0.000011510967],"about_ca_topic_score_codex":0.0007795792,"about_ca_topic_score_gemma":0.0009940388,"teacher_disagreement_score":0.0018289638,"about_ca_system_score_codex":0.00028906108,"about_ca_system_score_gemma":0.0001971745,"threshold_uncertainty_score":0.006118536},"labels":[],"label_agreement":null},{"id":"W4389801100","doi":"10.1007/s12975-023-01225-6","title":"Crosstalk Between Matrix Metalloproteinases and Their Inducer EMMPRIN/CD147: a Promising Therapeutic Target for Intracerebral Hemorrhage","year":2023,"lang":"en","type":"review","venue":"Translational Stroke Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Matrix metalloproteinase; Intracerebral hemorrhage; Medicine; Extracellular matrix; Crosstalk; Neuroinflammation; Cell biology; Metalloproteinase; Blood–brain barrier; Cancer research; Transmembrane protein; Neuroscience; Immunology; Inflammation; Biology; Internal medicine; Receptor; Central nervous system","score_opus":0.2360643552533369,"score_gpt":0.4646169425710229,"score_spread":0.22855258731768596,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4389801100","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000110870074,0.99831486,0.00013434254,0.0003068294,0.0003452596,0.0000041519793,0.000023490258,0.00000856407,0.0007516234],"genre_scores_gemma":[0.0007142967,0.9976845,0.00016581602,0.0002896879,0.00036118244,0.000009029151,0.00004243702,0.0000015983093,0.00073142414],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998784,0.00001901677,0.000015587402,0.00001955251,0.00004994966,0.000017477569],"domain_scores_gemma":[0.99983823,0.00006110034,0.000026767144,0.0000044369126,0.000047157893,0.000022144613],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005009631,0.0008800187,0.0012681452,0.0012279442,0.00018243547,0.0011356674,0.0007881705,0.0011348163,0.0031300145],"category_scores_gemma":[0.000579788,0.00024196692,0.0003373059,0.0013362118,0.0003648936,0.0010366668,0.0005780273,0.0019854296,0.0024563263],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00026994557,0.00010235654,0.00012417276,0.011493625,0.00010514713,0.0002609039,0.000029118608,0.00044548916,0.0036448704,0.0040820474,0.071211316,0.908231],"study_design_scores_gemma":[0.000087103894,0.0001422794,0.0006379465,0.0021515298,0.00016704731,0.00082401565,0.000037853475,0.00017188214,0.0008163491,0.0024415466,0.99249977,0.000022705577],"about_ca_topic_score_codex":0.0006794507,"about_ca_topic_score_gemma":0.0016286232,"teacher_disagreement_score":0.0031300145,"about_ca_system_score_codex":0.00060243276,"about_ca_system_score_gemma":0.0009165438,"threshold_uncertainty_score":0.010470927},"labels":[],"label_agreement":null},{"id":"W4391144586","doi":"10.1093/stmcls/sxae008","title":"Uterine Immunoprivileged Cells Restore Cardiac Function of Male Recipients After Myocardial Infarction","year":2024,"lang":"en","type":"article","venue":"Stem Cells","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto General Hospital; University Health Network","funders":"","keywords":"Major histocompatibility complex; MHC class I; CD8; Immunology; Biology; Cytotoxic T cell; Transplantation; MHC class II; Medicine; Internal medicine; Immune system; In vitro; Genetics","score_opus":0.007169496933460276,"score_gpt":0.225876848954006,"score_spread":0.21870735202054573,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391144586","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9952088,0.002161136,0.00094862765,0.00013168262,0.00013978535,0.0000324762,0.00014662264,0.000051466202,0.0011793354],"genre_scores_gemma":[0.9940849,0.0013708149,0.000684055,0.00012959003,0.00009908534,0.000066534296,0.00023352762,0.000024849107,0.0033067258],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998523,0.000025116471,0.000011306175,0.00002546222,0.00003470969,0.00005104456],"domain_scores_gemma":[0.9998522,0.000013063724,0.00004048866,0.000018945404,0.000009310624,0.00006591126],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002336773,0.00030599997,0.0005488322,0.00027130463,0.00015056627,0.00036269205,0.00019031894,0.00025054457,0.0023434667],"category_scores_gemma":[0.00021498466,0.00014336494,0.0002446922,0.00008577174,0.00019657586,0.00024496837,0.00024517678,0.0008710477,0.00052870286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021114224,0.0007071267,0.0008625656,0.000104165854,0.00001981249,0.00018427697,0.00008434948,0.00011029526,0.9816351,0.00022782398,0.00020460608,0.0137485955],"study_design_scores_gemma":[0.0005752404,0.026491549,0.039571855,0.00011507661,0.0002771666,0.0012877337,0.0005741944,0.002060924,0.917247,0.00035814906,0.011400341,0.000040734813],"about_ca_topic_score_codex":0.000109709894,"about_ca_topic_score_gemma":0.0001778789,"teacher_disagreement_score":0.0023434667,"about_ca_system_score_codex":0.000078401245,"about_ca_system_score_gemma":0.00014476433,"threshold_uncertainty_score":0.00783968},"labels":[],"label_agreement":null},{"id":"W4391486246","doi":"10.5194/egusphere-2023-2748-ac4","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Environment Research Council; Rheinische Friedrich-Wilhelms-Universität Bonn; Natural Sciences and Engineering Research Council of Canada; British Geological Survey; Deutsche Forschungsgemeinschaft","keywords":"Computer science","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391486246","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00016715763,0.001101377,0.00017278397,0.7832288,0.1979363,0.00008340782,0.000605339,0.00032588467,0.01637898],"genre_scores_gemma":[0.0019629863,0.00085201993,0.00022345777,0.81441206,0.07647798,0.0001331226,0.00028925596,0.00020119286,0.10544796],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99777526,0.0003052688,0.00026244784,0.0003693573,0.0009561414,0.0003315213],"domain_scores_gemma":[0.9899137,0.0026566081,0.0003702077,0.00045398826,0.0048912084,0.0017143227],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0026194605,0.0007649631,0.0009885767,0.0013116341,0.002743846,0.0037045714,0.0026643241,0.02080007,0.14371309],"category_scores_gemma":[0.027576644,0.0005321154,0.001057416,0.00090275065,0.0019899001,0.0036851575,0.0026602978,0.01788135,0.10031621],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000073061146,0.0000022273318,0.000029894934,0.00001162981,8.542092e-7,0.00003989123,0.000007024694,0.0000028758907,0.000017047207,0.00017911766,0.9981664,0.0015357705],"study_design_scores_gemma":[0.000011251807,0.0000063469306,0.0002486933,0.000051113813,0.0000023458394,0.00007168702,0.000053010997,0.000025683677,0.00004928715,0.0004770071,0.9989912,0.000012479868],"about_ca_topic_score_codex":0.009768375,"about_ca_topic_score_gemma":0.013433942,"teacher_disagreement_score":0.14371309,"about_ca_system_score_codex":0.0036389611,"about_ca_system_score_gemma":0.0035114833,"threshold_uncertainty_score":0.48076814},"labels":[],"label_agreement":null},{"id":"W4391850604","doi":"10.1016/j.cels.2024.01.009","title":"Widespread alteration of protein autoinhibition in human cancers","year":2024,"lang":"en","type":"article","venue":"Cell Systems","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Research Foundation of Korea; Canadian Institutes of Health Research; National Research Foundation; Genome Canada","keywords":"Allosteric regulation; Biology; Missense mutation; Cancer; Genetics; Mutation; Interactome; Transcriptome; Cancer cell; Computational biology; Gene; Receptor; Gene expression","score_opus":0.009521886676855548,"score_gpt":0.25064567228057383,"score_spread":0.24112378560371828,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4391850604","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99445796,0.0021142478,0.0010223864,0.00007768093,0.000008647099,0.0000054390207,0.0002207509,0.000094076444,0.0019988748],"genre_scores_gemma":[0.9989951,0.00030594793,0.00012678836,0.000011368883,0.0000035778146,0.0000018933615,0.00008059013,0.000007182858,0.00046751517],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999889,0.000016459499,0.000010141089,0.000029556148,0.000026170967,0.00002859494],"domain_scores_gemma":[0.9998306,0.000033209413,0.000039623996,0.0000380337,0.000020026093,0.000038543218],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011567035,0.00014690119,0.0002086126,0.0006673622,0.00019621893,0.000304415,0.00014600853,0.00015231728,0.0013121626],"category_scores_gemma":[0.00023791434,0.00011667844,0.00012309114,0.00046762725,0.00028205826,0.0001312246,0.00025788147,0.00022222495,0.00023794635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003337141,0.000021507964,0.011891217,0.00004442139,0.000026770258,0.0005109247,0.00005715396,0.0002168692,0.9771055,0.0006980244,0.00011116321,0.008982736],"study_design_scores_gemma":[0.000019051871,0.0003165803,0.43143106,0.000010343497,0.000090761125,0.00956692,0.0001997357,0.0013616481,0.54755735,0.0011854536,0.008245348,0.00001575466],"about_ca_topic_score_codex":0.001109474,"about_ca_topic_score_gemma":0.0009824098,"teacher_disagreement_score":0.0013121626,"about_ca_system_score_codex":0.00019310892,"about_ca_system_score_gemma":0.00018503351,"threshold_uncertainty_score":0.0043896437},"labels":[],"label_agreement":null},{"id":"W4392636266","doi":"","title":"Analyses des causes génétiques du syndrome de micro-délétion du 16p11.2 et de l’impact de la protéine majeure de la voute (MVP) et de son interaction avec MAPK3 dans la physiologie cérébrale","year":2021,"lang":"en","type":"preprint","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"University of California, Davis; Agence Nationale de la Recherche; Institute of Genetics; INFRAFRONTIER; Universität Basel","keywords":"Association (psychology); Autism; Neuroscience; Cranial vault; Biology; Genetics; Medicine; Bioinformatics; Psychology; Anatomy; Psychiatry","score_opus":0.02461385198497305,"score_gpt":0.3802292313321489,"score_spread":0.35561537934717585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4392636266","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99128914,0.0005963734,0.0061223833,0.00006122771,0.000025099635,0.000019677347,0.0006365998,0.00008122446,0.0011681854],"genre_scores_gemma":[0.9877065,0.0010976178,0.005937575,0.00004207214,0.000012270482,0.00007899759,0.0009206703,0.000053724838,0.004150635],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99984396,0.000016601565,0.000013650463,0.00006192212,0.00004063439,0.00002310035],"domain_scores_gemma":[0.9997174,0.00010463107,0.00008003506,0.000031768934,0.000020271109,0.000045766985],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017513732,0.00071553956,0.00029702025,0.0010893657,0.00023255375,0.00018730582,0.00020692537,0.00033654989,0.003338722],"category_scores_gemma":[0.00031161722,0.00025930285,0.00047258026,0.0003547453,0.0004922053,0.00013401828,0.00036823808,0.0003830808,0.00032997745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018733543,0.000019635756,0.011404487,0.00008177346,0.0000740648,0.0037435319,0.00014830254,0.00022372587,0.97900003,0.00048338107,0.000064975065,0.004568728],"study_design_scores_gemma":[0.00007197721,0.0004365499,0.26312998,0.00004467428,0.000349916,0.03377841,0.00038591435,0.0020230727,0.68956465,0.0010307078,0.00913915,0.000044954508],"about_ca_topic_score_codex":0.0013032202,"about_ca_topic_score_gemma":0.002112984,"teacher_disagreement_score":0.003338722,"about_ca_system_score_codex":0.00015361745,"about_ca_system_score_gemma":0.00019616412,"threshold_uncertainty_score":0.011169136},"labels":[],"label_agreement":null},{"id":"W4393072815","doi":"10.1158/1538-7445.am2024-2648","title":"Abstract 2648: CD155 regulates cell growth and immune evasion in diffuse midline glioma","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Evasion (ethics); Immune system; Glioma; Immune escape; Medicine; Anatomy; Biology; Immunology; Cancer research","score_opus":0.03497036371567701,"score_gpt":0.35787530168806553,"score_spread":0.3229049379723885,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393072815","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99615484,0.0013652715,0.0004919118,0.000063362626,0.000014042104,0.000012182018,0.00025384966,0.000042558448,0.0016020255],"genre_scores_gemma":[0.9978909,0.0003173789,0.0002427666,0.00002933189,0.0000051153547,0.000008812264,0.00020733032,0.000005379662,0.0012929199],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999343,0.0000086376585,0.0000048138572,0.000014290287,0.000016837559,0.00002122641],"domain_scores_gemma":[0.99996865,0.0000033332692,0.000010958414,0.0000022043903,0.0000029541186,0.000011856287],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005192859,0.00023757866,0.00014740688,0.00015311761,0.00008779227,0.0001981024,0.00010852248,0.00023655382,0.001255476],"category_scores_gemma":[0.00005708929,0.00006688719,0.000111964626,0.0000797329,0.00013506836,0.00009024355,0.0001234646,0.00031200366,0.00046277733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010822121,0.000014773779,0.000480985,0.000025537176,0.0000021882329,0.00013254053,0.000007722477,0.000048418264,0.9982023,0.00005764751,0.000064157546,0.0008556212],"study_design_scores_gemma":[0.00005437761,0.00075735076,0.038078066,0.00001861089,0.000022201028,0.001755448,0.000102641134,0.0013300516,0.9519572,0.000084247156,0.005834181,0.000005657616],"about_ca_topic_score_codex":0.0006316563,"about_ca_topic_score_gemma":0.0006801151,"teacher_disagreement_score":0.001255476,"about_ca_system_score_codex":0.00031210153,"about_ca_system_score_gemma":0.00013347104,"threshold_uncertainty_score":0.0041999817},"labels":[],"label_agreement":null},{"id":"W4393471979","doi":"10.3389/fcell.2024.1343962","title":"The role of the Pin1-cis P-tau axis in the development and treatment of vascular contribution to cognitive impairment and dementia and preeclampsia","year":2024,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Tauopathy; PIN1; Neurodegeneration; Dementia; Neuroscience; Disease; Vascular dementia; Medicine; Frontotemporal dementia; Cognition; Psychology; Bioinformatics; Internal medicine; Biology; Genetics","score_opus":0.0048762826051511055,"score_gpt":0.2128509742265298,"score_spread":0.2079746916213787,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393471979","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15192616,0.79748935,0.0136962235,0.012243717,0.0016221179,0.00013423081,0.0005585525,0.0005272872,0.02180235],"genre_scores_gemma":[0.5926025,0.38752696,0.009079783,0.0024462666,0.0013029347,0.00021207624,0.00055653625,0.00005758815,0.0062153935],"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.99977165,0.00006673557,0.00001925204,0.000036283087,0.00005820975,0.000047916063],"domain_scores_gemma":[0.99979824,0.00004859771,0.00004794339,0.000013084365,0.000047217927,0.000044955224],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00053355604,0.00037237402,0.00056385214,0.0005362629,0.00029351385,0.00079686096,0.00046863218,0.0005650896,0.0015392671],"category_scores_gemma":[0.0006707211,0.0001205834,0.00039915336,0.0002766739,0.00048165247,0.000490498,0.00060595263,0.001729519,0.0003633825],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0048024026,0.0009537465,0.006128487,0.003681378,0.0004425423,0.003422457,0.0003396285,0.0017739362,0.12833643,0.028448801,0.016946465,0.8047238],"study_design_scores_gemma":[0.0016896873,0.00806008,0.06126669,0.0033212032,0.0013716305,0.01666034,0.0010392141,0.00828791,0.19825791,0.0797802,0.62003773,0.00022731202],"about_ca_topic_score_codex":0.0005314162,"about_ca_topic_score_gemma":0.00081933534,"teacher_disagreement_score":0.0015392671,"about_ca_system_score_codex":0.0005004272,"about_ca_system_score_gemma":0.0006995138,"threshold_uncertainty_score":0.0051493645},"labels":[],"label_agreement":null},{"id":"W4393477466","doi":"10.5281/zenodo.5903022","title":"CAPN2: A Target Enabling Package","year":2025,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"R package; Computer science; Programming language","score_opus":0.01968928103274631,"score_gpt":0.25382333460535933,"score_spread":0.23413405357261302,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393477466","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024238917,0.00017546317,0.00018519777,0.00005710211,0.00001333265,0.000017208507,0.997603,0.0008422562,0.0008640217],"genre_scores_gemma":[0.0008826136,0.00015156604,0.0006908657,0.000057697373,0.000004922213,0.00012727527,0.99732554,0.0002039087,0.0005555694],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99931324,0.00015476186,0.00007199849,0.00025127185,0.00012957491,0.000079219106],"domain_scores_gemma":[0.9989512,0.00043817257,0.000120403674,0.00019800614,0.00016907057,0.00012309205],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008821175,0.0017712201,0.0011444346,0.0021551198,0.0005186897,0.0017589654,0.0020335722,0.0012572171,0.08889399],"category_scores_gemma":[0.004756441,0.00054358126,0.0012518889,0.0039537637,0.00027423393,0.0010495615,0.0014553249,0.0010499881,0.071973935],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027275746,0.000026194415,0.0019374683,0.0034792065,0.00016683635,0.00006847329,0.00004502917,0.0012878075,0.00065764796,0.0012230092,0.9834161,0.0074194153],"study_design_scores_gemma":[0.0003419938,0.00003183537,0.003297512,0.00035531708,0.00008979549,0.00007517061,0.000041976666,0.00075262896,0.0007257391,0.001960866,0.9923005,0.00002669383],"about_ca_topic_score_codex":0.007422458,"about_ca_topic_score_gemma":0.01886638,"teacher_disagreement_score":0.08889399,"about_ca_system_score_codex":0.0008605025,"about_ca_system_score_gemma":0.0016049836,"threshold_uncertainty_score":0.29737997},"labels":[],"label_agreement":null},{"id":"W4393540285","doi":"10.5281/zenodo.3256589","title":"PACN1 Purification","year":2019,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Computer science","score_opus":0.035746418324527185,"score_gpt":0.263740235716753,"score_spread":0.2279938173922258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393540285","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014551998,0.0006898126,0.00043477834,0.000078708144,0.000043539036,0.000030404479,0.9946057,0.001249424,0.0014123858],"genre_scores_gemma":[0.000930598,0.00014157679,0.0007019707,0.00004054673,0.0000032316268,0.00007472044,0.99757665,0.000109979504,0.0004206953],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99847025,0.00020967297,0.00015550175,0.000670499,0.0003216315,0.00017245386],"domain_scores_gemma":[0.99886876,0.0003240077,0.00013181822,0.000346877,0.00020907682,0.000119389064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017591789,0.0034786556,0.0021412382,0.003265504,0.0010970174,0.0026518777,0.0029064242,0.002397334,0.02487619],"category_scores_gemma":[0.0047043455,0.0007077829,0.0018132776,0.0048384685,0.00054836477,0.0012601358,0.0018566826,0.0020651782,0.04960397],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009509584,0.00013061988,0.0057778717,0.0061572,0.0004036135,0.00030650612,0.0000909181,0.002523328,0.0058857454,0.0019641616,0.96038747,0.015421684],"study_design_scores_gemma":[0.0005846295,0.00009960188,0.008845545,0.0004766531,0.00027182663,0.00039722607,0.00007542474,0.0017319744,0.0052105095,0.0027368243,0.97950786,0.000061951054],"about_ca_topic_score_codex":0.00904884,"about_ca_topic_score_gemma":0.016133636,"teacher_disagreement_score":0.02487619,"about_ca_system_score_codex":0.0013941533,"about_ca_system_score_gemma":0.002387508,"threshold_uncertainty_score":0.08321911},"labels":[],"label_agreement":null},{"id":"W4393590926","doi":"10.5281/zenodo.3256588","title":"PACN1 Purification","year":2019,"lang":"en","type":"dataset","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry","score_opus":0.035746418324527185,"score_gpt":0.263740235716753,"score_spread":0.2279938173922258,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4393590926","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0014551998,0.0006898126,0.00043477834,0.000078708144,0.000043539036,0.000030404479,0.9946057,0.001249424,0.0014123858],"genre_scores_gemma":[0.000930598,0.00014157679,0.0007019707,0.00004054673,0.0000032316268,0.00007472044,0.99757665,0.000109979504,0.0004206953],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99847025,0.00020967297,0.00015550175,0.000670499,0.0003216315,0.00017245386],"domain_scores_gemma":[0.99886876,0.0003240077,0.00013181822,0.000346877,0.00020907682,0.000119389064],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017591789,0.0034786556,0.0021412382,0.003265504,0.0010970174,0.0026518777,0.0029064242,0.002397334,0.02487619],"category_scores_gemma":[0.0047043455,0.0007077829,0.0018132776,0.0048384685,0.00054836477,0.0012601358,0.0018566826,0.0020651782,0.04960397],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009509584,0.00013061988,0.0057778717,0.0061572,0.0004036135,0.00030650612,0.0000909181,0.002523328,0.0058857454,0.0019641616,0.96038747,0.015421684],"study_design_scores_gemma":[0.0005846295,0.00009960188,0.008845545,0.0004766531,0.00027182663,0.00039722607,0.00007542474,0.0017319744,0.0052105095,0.0027368243,0.97950786,0.000061951054],"about_ca_topic_score_codex":0.00904884,"about_ca_topic_score_gemma":0.016133636,"teacher_disagreement_score":0.02487619,"about_ca_system_score_codex":0.0013941533,"about_ca_system_score_gemma":0.002387508,"threshold_uncertainty_score":0.08321911},"labels":[],"label_agreement":null},{"id":"W4394120596","doi":"10.6084/m9.figshare.19905958","title":"Additional file 9 of BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c-Fos/NFATc1","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Bone resorption; Chemistry; Resorption; Cell biology; Internal medicine; Medicine; Biology","score_opus":0.014073333067643686,"score_gpt":0.22335550576333926,"score_spread":0.20928217269569557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394120596","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000044018172,0.000028972794,0.000031046475,0.00003566611,0.0000067075316,0.000008563623,0.99955446,0.00007667643,0.00021381797],"genre_scores_gemma":[0.0014057637,0.000116125964,0.00055455416,0.0001968156,0.000020709876,0.0003648625,0.9956255,0.00017205898,0.0015436792],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9991875,0.00012377207,0.00010722353,0.00029206034,0.00015380447,0.00013563375],"domain_scores_gemma":[0.9920758,0.0054138303,0.0005392153,0.00066275545,0.00094678416,0.000361599],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011401344,0.0018095726,0.0020398148,0.0022897033,0.0009340788,0.0026143254,0.002477299,0.0023885805,0.59521043],"category_scores_gemma":[0.015023903,0.00077854027,0.0017397602,0.003933837,0.00034167903,0.0016668028,0.0013788844,0.0012488799,0.14789456],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027786227,0.000043940054,0.0020640409,0.0042474344,0.00010813794,0.000042248354,0.000028759649,0.0003544635,0.00015839122,0.00040627967,0.9885515,0.0037168716],"study_design_scores_gemma":[0.0047946437,0.0001330937,0.020110976,0.0030563928,0.0004356053,0.00029059692,0.00014030226,0.0008652519,0.0008529218,0.0065118005,0.9627022,0.0001061825],"about_ca_topic_score_codex":0.011375986,"about_ca_topic_score_gemma":0.020985235,"teacher_disagreement_score":0.59521043,"about_ca_system_score_codex":0.0012726021,"about_ca_system_score_gemma":0.0020045328,"threshold_uncertainty_score":0.57738316},"labels":[],"label_agreement":null},{"id":"W4394470422","doi":"10.6084/m9.figshare.19905955","title":"Additional file 8 of BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c-Fos/NFATc1","year":2022,"lang":"en","type":"dataset","venue":"Figshare","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Bone resorption; Resorption; Chemistry; Internal medicine; Medicine","score_opus":0.014066364887978699,"score_gpt":0.22332514859186167,"score_spread":0.20925878370388298,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394470422","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.000045585435,0.000024273424,0.00004224532,0.0000320283,0.000006660757,0.000013041129,0.99956506,0.000079907324,0.00019110015],"genre_scores_gemma":[0.0015483998,0.000107202206,0.0008538046,0.00021544247,0.000022763255,0.0006203033,0.99444336,0.00024429295,0.0019444736],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990491,0.00015944186,0.00013191937,0.00033646528,0.00017707206,0.00014584676],"domain_scores_gemma":[0.9891248,0.007856245,0.00062735874,0.0007744578,0.0012332775,0.00038379748],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0013894155,0.0018647859,0.0020916476,0.002353656,0.0010610664,0.0027389927,0.0025514825,0.0024557621,0.64404947],"category_scores_gemma":[0.017702835,0.00085162284,0.0017726017,0.0037691307,0.00036942036,0.0016434025,0.0014145776,0.0013663216,0.15636809],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00035950268,0.000060272236,0.0023565253,0.0050024567,0.00010415887,0.000047672034,0.000042552903,0.0004011527,0.0001656217,0.00040777164,0.9860437,0.0050084805],"study_design_scores_gemma":[0.00589939,0.00016658666,0.022502055,0.0038030508,0.00046773566,0.00030035884,0.00020050885,0.0010401935,0.0009837828,0.007440464,0.9570631,0.00013298912],"about_ca_topic_score_codex":0.010411719,"about_ca_topic_score_gemma":0.019280598,"teacher_disagreement_score":0.64404947,"about_ca_system_score_codex":0.0012608189,"about_ca_system_score_gemma":0.0022189652,"threshold_uncertainty_score":0.50772023},"labels":[],"label_agreement":null},{"id":"W4394688780","doi":"10.1101/2024.04.09.588654","title":"Structure of Calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; British Columbia Knowledge Development Fund; Michael Smith Health Research BC","keywords":"Calcineurin; Dual (grammatical number); Interface (matter); Computer science; Parallel computing; Medicine; Art; Internal medicine; Transplantation","score_opus":0.009922076417098016,"score_gpt":0.24542353838660377,"score_spread":0.23550146196950575,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394688780","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994272,0.0005992259,0.0018852467,0.0002755129,0.000031964122,0.000009361253,0.000369056,0.00018405664,0.0023736274],"genre_scores_gemma":[0.9908285,0.00049783575,0.002645565,0.00007136702,0.000009295458,0.000008795728,0.0021767938,0.00005949618,0.0037023386],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994934,0.0000046704727,0.0000018929987,0.000011863386,0.00002074963,0.0000114969525],"domain_scores_gemma":[0.9999391,0.0000134883785,0.000015832062,0.000004159587,0.000008062524,0.000019336878],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000086298285,0.00033777824,0.0002433284,0.00016850792,0.00050062494,0.0003516427,0.0005865127,0.0005995136,0.0036212157],"category_scores_gemma":[0.0001795165,0.00015834076,0.00025918643,0.00024422441,0.00026715227,0.00031796255,0.00028221562,0.0008710723,0.00040933717],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0013477919,0.00028545395,0.005638623,0.00036348702,0.00012168501,0.0035290483,0.0004522022,0.009349652,0.9651449,0.0029355637,0.0032894535,0.0075421925],"study_design_scores_gemma":[0.00059944694,0.00087802386,0.1179285,0.00018619052,0.00017526446,0.005070771,0.00089974015,0.23901993,0.6032686,0.002524144,0.029277561,0.00017184732],"about_ca_topic_score_codex":0.0049929707,"about_ca_topic_score_gemma":0.0030778034,"teacher_disagreement_score":0.0049929707,"about_ca_system_score_codex":0.0008758812,"about_ca_system_score_gemma":0.00031246294,"threshold_uncertainty_score":0.012114167},"labels":[],"label_agreement":null},{"id":"W4394817665","doi":"10.1101/2024.04.14.589449","title":"ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Cell cycle progression; Control (management); Cell cycle; Cell biology; Cell; Computer science; Chemistry; Biology; Genetics; Artificial intelligence","score_opus":0.008113043494418212,"score_gpt":0.23146432350831594,"score_spread":0.22335128001389773,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394817665","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98835725,0.0020478484,0.0038389468,0.00021015308,0.00004689623,0.000018286131,0.00094093493,0.00034231757,0.004197348],"genre_scores_gemma":[0.9836036,0.0009424514,0.003108441,0.00005022097,0.000019288907,0.000022386344,0.001322578,0.00010613262,0.010824803],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999391,0.000010040186,0.0000033463725,0.000015168891,0.000015745558,0.000016597412],"domain_scores_gemma":[0.9999379,0.0000073298593,0.000019770794,0.000009788765,0.000007903842,0.000017352811],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009232239,0.00038555916,0.00018577123,0.0004973858,0.00019887873,0.00029929544,0.0002225606,0.00026007334,0.002316856],"category_scores_gemma":[0.000074301846,0.00013285052,0.00015661231,0.00015498222,0.00024518004,0.00013808689,0.0002571192,0.00028946428,0.0012412955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00018831037,0.000014046418,0.00053291844,0.000030805568,0.0000059622166,0.00015180552,0.000006305908,0.00015834489,0.99657106,0.00035063742,0.00017961198,0.0018101749],"study_design_scores_gemma":[0.000025039393,0.000057976984,0.0054775,0.000005217217,0.000008377441,0.0003486354,0.000015055053,0.0015611795,0.9876036,0.00017881107,0.00471515,0.00000351219],"about_ca_topic_score_codex":0.0004199897,"about_ca_topic_score_gemma":0.0005444182,"teacher_disagreement_score":0.002316856,"about_ca_system_score_codex":0.00030768674,"about_ca_system_score_gemma":0.00015608323,"threshold_uncertainty_score":0.00775069},"labels":[],"label_agreement":null},{"id":"W4395034756","doi":"10.3390/cells13090731","title":"Pin1-Catalyzed Conformation Changes Regulate Protein Ubiquitination and Degradation","year":2024,"lang":"en","type":"review","venue":"Cells","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research; Canada Foundation for Innovation","keywords":"PIN1; Ubiquitin; Proteasome; Prolyl isomerase; Phosphorylation; Context (archaeology); Cell biology; Protein turnover; Suppressor; Chemistry; Function (biology); Protein degradation; Posttranslational modification; Biochemistry; Isomerase; Biology; Enzyme; Protein biosynthesis; Gene","score_opus":0.02911563612337932,"score_gpt":0.29956931101256995,"score_spread":0.27045367488919064,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395034756","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0018207531,0.9915998,0.0009224809,0.00023333426,0.00023177822,0.000017220918,0.00008728199,0.000043609853,0.0050436864],"genre_scores_gemma":[0.008454244,0.9876029,0.00055313355,0.00018062028,0.00008763421,0.000022075139,0.0001220916,0.000004764787,0.0029724475],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999112,0.000010663377,0.000008593485,0.000018595114,0.000029878955,0.000020998586],"domain_scores_gemma":[0.9999609,0.000010494755,0.000009521344,0.0000021877318,0.000011065479,0.00000577105],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002275785,0.0007103413,0.00061998965,0.00081080594,0.00018574022,0.0006896211,0.0005290227,0.0005547741,0.002263189],"category_scores_gemma":[0.00015882934,0.00023799624,0.00028450356,0.00063839054,0.00024043785,0.00065771065,0.00046085712,0.0007784242,0.0018360512],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020535773,0.000092118855,0.0003351962,0.0129730245,0.0001346313,0.00046215008,0.00005834121,0.0009840659,0.066200264,0.011021556,0.01874244,0.88879097],"study_design_scores_gemma":[0.000028556598,0.00015311895,0.001213137,0.0008120473,0.000080624166,0.0018775086,0.000047766414,0.0003452998,0.035101835,0.002772979,0.9575382,0.00002896072],"about_ca_topic_score_codex":0.00031489815,"about_ca_topic_score_gemma":0.0006595731,"teacher_disagreement_score":0.002263189,"about_ca_system_score_codex":0.00049233297,"about_ca_system_score_gemma":0.00039256405,"threshold_uncertainty_score":0.007571101},"labels":[],"label_agreement":null},{"id":"W4395040918","doi":"10.1161/circ.126.suppl_21.a19538","title":"Abstract 19538: Integrin-Linked Kinase Regulates Cardiomyocyte Calcium Signaling through Protein-Protein Interaction with Sarcoplasmic Reticulum Calcium ATPase","year":2012,"lang":"en","type":"article","venue":"Circulation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Endoplasmic reticulum; Medicine; Calcium; Calcium ATPase; Cell biology; Protein kinase A; Ryanodine receptor 2; Ryanodine receptor; ATPase; Sarcoplasm; Calcium signaling; Internal medicine; Kinase; Biochemistry; Enzyme; Biology","score_opus":0.0314873235868074,"score_gpt":0.27780781230213886,"score_spread":0.24632048871533146,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395040918","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8945758,0.039209004,0.009929847,0.003442577,0.0020163727,0.0003605315,0.01475036,0.0019286501,0.033786852],"genre_scores_gemma":[0.92172205,0.009468074,0.0063371225,0.00059919414,0.00034818045,0.00036369558,0.010841538,0.00019181317,0.050128404],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999764,0.000022667817,0.000024281358,0.00006911135,0.000067973975,0.00005198993],"domain_scores_gemma":[0.99994576,0.0000038754647,0.000015380005,0.0000043192185,0.0000065824493,0.000024055451],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00017924797,0.00087978103,0.0003985182,0.00027388457,0.00046601507,0.0004267738,0.00046739663,0.00047151066,0.016147085],"category_scores_gemma":[0.00012941186,0.00022596205,0.0003869776,0.00030843716,0.00023403316,0.000384341,0.00035029612,0.0008112372,0.004114722],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0008237804,0.000101121244,0.00028649473,0.00037818425,0.000021661332,0.00027193647,0.00003563994,0.000094963725,0.9854197,0.0006116016,0.002727424,0.009227447],"study_design_scores_gemma":[0.00046750664,0.0012531738,0.014084606,0.000081051105,0.00011713196,0.001573602,0.00009333455,0.0013952985,0.9004474,0.0004320861,0.08002501,0.000029798815],"about_ca_topic_score_codex":0.0007388428,"about_ca_topic_score_gemma":0.00085185206,"teacher_disagreement_score":0.016147085,"about_ca_system_score_codex":0.00072231167,"about_ca_system_score_gemma":0.00039329185,"threshold_uncertainty_score":0.054017365},"labels":[],"label_agreement":null},{"id":"W4395054146","doi":"10.5194/egusphere-2023-2764-ac1","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"Guangdong Academy of Sciences; Japan Agency for Marine-Earth Science and Technology; National Park Service; Ministry of Science and ICT, South Korea; University of California, Davis; U.S. Environmental Protection Agency; National Research Foundation of Korea; Korea Polar Research Institute; National Research Foundation; National Oceanic and Atmospheric Administration; Desert Research Institute","keywords":"Environmental science","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395054146","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002914773,0.0018501214,0.00026901206,0.71087503,0.24089661,0.00015313146,0.0010172355,0.0006383205,0.044009183],"genre_scores_gemma":[0.003233447,0.0013575017,0.00024386037,0.73947257,0.08019723,0.00021916657,0.0004905408,0.00027813076,0.17450751],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99841213,0.00028747917,0.00018267745,0.00027379964,0.00056240027,0.00028146396],"domain_scores_gemma":[0.9946067,0.001728381,0.00023956293,0.0002793372,0.0022474325,0.00089867937],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00183725,0.0009480399,0.0010324956,0.0011856033,0.002620212,0.0032072633,0.0025969024,0.02066351,0.23098515],"category_scores_gemma":[0.021315861,0.0005240039,0.0012517727,0.0008312521,0.001682317,0.00317433,0.0024280064,0.016594773,0.13957056],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009965721,0.0000030861265,0.000036736234,0.000012611099,9.05373e-7,0.000059560873,0.000007394413,0.0000034868426,0.000015098418,0.00016735241,0.9975922,0.0020916339],"study_design_scores_gemma":[0.000014822157,0.000009386326,0.00023839601,0.00006654071,0.0000024978779,0.000109182285,0.00007131339,0.000030628682,0.000056870034,0.0004687429,0.9989213,0.0000104031415],"about_ca_topic_score_codex":0.0064764153,"about_ca_topic_score_gemma":0.008086456,"teacher_disagreement_score":0.23098515,"about_ca_system_score_codex":0.0029503272,"about_ca_system_score_gemma":0.0023873423,"threshold_uncertainty_score":0.7727223},"labels":[],"label_agreement":null},{"id":"W4395089285","doi":"10.5194/gchron-2024-1-ac3","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4395089285","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00020687297,0.0011588404,0.00022329428,0.8345745,0.1479163,0.00007723506,0.00070269796,0.00036302162,0.014777257],"genre_scores_gemma":[0.002834272,0.0011011267,0.00030064784,0.83677095,0.065526724,0.00016922526,0.0004256027,0.00031458982,0.092556834],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975074,0.00041903526,0.00028912563,0.00037918214,0.0010113443,0.0003939608],"domain_scores_gemma":[0.9866985,0.004077287,0.00047355035,0.0005765259,0.006263459,0.0019106662],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0030456276,0.0007873072,0.0010151753,0.0014420954,0.0028103911,0.0034874321,0.0024571514,0.021028263,0.12576924],"category_scores_gemma":[0.041670073,0.00045543787,0.0010628104,0.0010628429,0.0018786498,0.0035686467,0.0023422365,0.016442915,0.084502056],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008281518,0.0000019110755,0.000037499227,0.000012682842,9.466376e-7,0.000053267926,0.000008833159,0.0000032048044,0.000017430712,0.00021672038,0.99818254,0.0014567912],"study_design_scores_gemma":[0.000011643723,0.00000712286,0.00027864595,0.000068424626,0.0000032374644,0.00012008038,0.00006587245,0.000031053867,0.000074108604,0.0005869857,0.99873847,0.00001452059],"about_ca_topic_score_codex":0.010250096,"about_ca_topic_score_gemma":0.012482515,"teacher_disagreement_score":0.12576924,"about_ca_system_score_codex":0.0038051126,"about_ca_system_score_gemma":0.0040690033,"threshold_uncertainty_score":0.42074},"labels":[],"label_agreement":null},{"id":"W4396514128","doi":"10.3389/fcell.2024.1343938","title":"The role of the master cancer regulator Pin1 in the development and treatment of cancer","year":2024,"lang":"en","type":"article","venue":"Frontiers in Cell and Developmental Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Robarts Clinical Trials; Lawson Health Research Institute; Western University","funders":"Canadian Institutes of Health Research","keywords":"Cancer; Regulator; Master regulator; PIN1; Cancer treatment; Cancer research; Medicine; Biology; Internal medicine; Transcription factor; Genetics","score_opus":0.00907774363679271,"score_gpt":0.23250507985694216,"score_spread":0.22342733622014946,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4396514128","genre_codex":"review","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010443589,0.993856,0.00074943766,0.0013075985,0.00057374046,0.000007379932,0.000025213349,0.000020814914,0.0024154945],"genre_scores_gemma":[0.007990691,0.9887982,0.00067373406,0.00054658134,0.0005795109,0.000013710116,0.00003684024,0.0000047717817,0.0013561036],"study_design_codex":"design_other","study_design_gemma":"observational","domain_scores_codex":[0.99978787,0.000043164022,0.000017063097,0.000033471257,0.00008502227,0.00003345798],"domain_scores_gemma":[0.99985886,0.000060531587,0.000022300885,0.0000052245296,0.000029036615,0.000024004708],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005514617,0.00046034672,0.0006295464,0.00072452263,0.00029363783,0.000817706,0.00045931397,0.000596426,0.0017276594],"category_scores_gemma":[0.00052406284,0.00016648331,0.00031077815,0.00058907404,0.0005500365,0.0010492017,0.0005460105,0.0013845606,0.0007421747],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034360468,0.00005742917,0.00068680674,0.007727634,0.000105601204,0.0011049722,0.00020766299,0.0019859716,0.034332152,0.02803721,0.04034061,0.8850703],"study_design_scores_gemma":[0.000017792721,0.00022519204,0.0012910343,0.0008183575,0.00005134618,0.002382316,0.000093008195,0.00024532786,0.0065215104,0.006411583,0.9819224,0.000020208456],"about_ca_topic_score_codex":0.00042062913,"about_ca_topic_score_gemma":0.0007649631,"teacher_disagreement_score":0.0017276594,"about_ca_system_score_codex":0.00076369825,"about_ca_system_score_gemma":0.0007726288,"threshold_uncertainty_score":0.005779624},"labels":[],"label_agreement":null},{"id":"W4397029865","doi":"10.1101/2024.05.15.594354","title":"Netrin G1 Ligand is a new stromal immunomodulator that promotes pancreatic cancer","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Pancreas Centre (Canada)","funders":"","keywords":"Pancreatic cancer; Stromal cell; Netrin; Cancer research; Ligand (biochemistry); Chemistry; Cancer; Cell biology; Medicine; Internal medicine; Biology; Receptor; Biochemistry","score_opus":0.01613029908577751,"score_gpt":0.23985141484591935,"score_spread":0.22372111576014184,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4397029865","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9953909,0.002488669,0.0007800771,0.00012333752,0.000024298159,0.00001138265,0.0001081769,0.000054490552,0.0010185449],"genre_scores_gemma":[0.9975459,0.00093191257,0.00037458248,0.000046412042,0.000010214,0.000010583701,0.00011266629,0.0000044491585,0.0009633381],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995804,0.000009174112,0.0000035519633,0.000008701055,0.00001016152,0.000010390942],"domain_scores_gemma":[0.9999541,0.000004297925,0.000017239116,0.000002629274,0.000003461631,0.00001818528],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006269633,0.00019326973,0.00011260126,0.0001785166,0.000087185996,0.00017236336,0.000067421584,0.00012814399,0.00080450246],"category_scores_gemma":[0.00004947947,0.000052824576,0.00011160253,0.00010220216,0.0001229281,0.000104142404,0.0001577592,0.00027292114,0.000109496264],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034920184,0.00003529605,0.0028469812,0.0000815426,0.000014273818,0.00025280472,0.000014177874,0.000079850965,0.9913799,0.00009625207,0.00012522405,0.0047244015],"study_design_scores_gemma":[0.00007972215,0.0012006516,0.07970994,0.000024371268,0.00012252897,0.002428415,0.0001256806,0.002215441,0.90110064,0.00020522266,0.012776564,0.000010758621],"about_ca_topic_score_codex":0.00015753297,"about_ca_topic_score_gemma":0.00028953658,"teacher_disagreement_score":0.00080450246,"about_ca_system_score_codex":0.00015106527,"about_ca_system_score_gemma":0.00008537401,"threshold_uncertainty_score":0.0026913881},"labels":[],"label_agreement":null},{"id":"W4398770969","doi":"10.5194/egusphere-2023-3013-ac1","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Environment and Climate Change Canada","funders":"","keywords":"Chemistry","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4398770969","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00020766252,0.0010405446,0.00031603078,0.7547799,0.21865791,0.00010513443,0.0010612623,0.0005345638,0.023297004],"genre_scores_gemma":[0.002378951,0.00095998583,0.0003490105,0.78748614,0.09342513,0.00021110867,0.0005805946,0.00038004183,0.11422908],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99731296,0.00041957453,0.00031601,0.0004016676,0.0011552785,0.00039448342],"domain_scores_gemma":[0.9853876,0.0045116604,0.0004727785,0.0007160254,0.0071308394,0.0017809954],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0032458557,0.00081336,0.0010093225,0.0015230421,0.002991951,0.0040719067,0.0027259884,0.0222339,0.15710157],"category_scores_gemma":[0.03831291,0.00054693734,0.0011550632,0.001066578,0.002147838,0.0039425204,0.0024383953,0.017453406,0.113295436],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000063299067,0.0000020412047,0.000026834163,0.000010999326,7.088034e-7,0.000030212208,0.0000064584415,0.0000029628713,0.000016633103,0.00018726701,0.99829096,0.001418701],"study_design_scores_gemma":[0.000011314595,0.000006713624,0.00025812312,0.000065230764,0.0000024716728,0.00006748612,0.000057280253,0.000028575452,0.000073058334,0.00057041127,0.9988464,0.000012878577],"about_ca_topic_score_codex":0.009046163,"about_ca_topic_score_gemma":0.010924914,"teacher_disagreement_score":0.15710157,"about_ca_system_score_codex":0.0029865822,"about_ca_system_score_gemma":0.0037909981,"threshold_uncertainty_score":0.5255571},"labels":[],"label_agreement":null},{"id":"W4399767204","doi":"10.1126/scisignal.adi8743","title":"Pin1-catalyzed conformational regulation after phosphorylation: A distinct checkpoint in cell signaling and drug discovery","year":2024,"lang":"en","type":"review","venue":"Science Signaling","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"National Institute of Neurological Disorders and Stroke; National Cancer Institute; National Institute on Aging; National Institutes of Health","keywords":"PIN1; Phosphorylation; Prolyl isomerase; Signal transduction; Kinase; Drug discovery; Peptidylprolyl isomerase; FKBP; Biology; Phosphatase; Cell biology; Isomerase; Cancer research; Biochemistry; Enzyme","score_opus":0.016137279746007323,"score_gpt":0.28311912607081985,"score_spread":0.26698184632481253,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399767204","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00037991253,0.9950954,0.0005212735,0.00048732513,0.0004243359,0.000013557338,0.000041534466,0.000021912814,0.0030147627],"genre_scores_gemma":[0.0019161213,0.99513274,0.000365013,0.00038235015,0.00016089054,0.000015102921,0.00006314941,0.0000038670682,0.0019607295],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998579,0.000022873146,0.000011407255,0.000028023189,0.00005204025,0.00002764103],"domain_scores_gemma":[0.99987984,0.000046310637,0.000016266331,0.0000053354556,0.000032261534,0.000020017684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000513727,0.00082603603,0.0010159479,0.0013332792,0.00028884207,0.0011673816,0.0008081544,0.000905042,0.0034369247],"category_scores_gemma":[0.0003396557,0.00032674902,0.00042681082,0.0013825868,0.00053970184,0.0015603185,0.00082225277,0.002189896,0.0026652187],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014381498,0.00008838941,0.00014152026,0.0135608325,0.00008239875,0.00042319304,0.00007815968,0.00072040857,0.011835156,0.020165041,0.0426621,0.9100989],"study_design_scores_gemma":[0.000018183648,0.00010672904,0.00025704742,0.00078197685,0.000036597077,0.00068774144,0.00002860231,0.000115364084,0.0021308588,0.0030642727,0.99275535,0.000017267266],"about_ca_topic_score_codex":0.0004401508,"about_ca_topic_score_gemma":0.0010796933,"teacher_disagreement_score":0.0034369247,"about_ca_system_score_codex":0.00077541464,"about_ca_system_score_gemma":0.0007024053,"threshold_uncertainty_score":0.011497676},"labels":[],"label_agreement":null},{"id":"W4399805121","doi":"10.1038/s41467-024-49427-2","title":"The DIAPH3 linker specifies a β-actin network that maintains RhoA and Myosin-II at the cytokinetic furrow","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"RHOA; Myosin; Linker; Actin; Cell biology; Chemistry; Computer science; Biology; Programming language; Signal transduction","score_opus":0.018394554671532958,"score_gpt":0.2868216891803219,"score_spread":0.26842713450878897,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4399805121","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9691018,0.0013309342,0.017217254,0.00022288284,0.00007465413,0.000058732923,0.002358106,0.00037598447,0.009259618],"genre_scores_gemma":[0.97604877,0.0005502744,0.010226478,0.00014171281,0.000010421992,0.000046554436,0.0024794748,0.00016936976,0.010326856],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99990296,0.000007215046,0.0000052014534,0.0000312757,0.00003067809,0.000022662818],"domain_scores_gemma":[0.99986756,0.00001995749,0.000047898593,0.000013480431,0.000009017483,0.000041971616],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006908131,0.0002881061,0.00013220122,0.00030104685,0.0003775087,0.0003365767,0.00022744919,0.0003021519,0.0032852571],"category_scores_gemma":[0.00010511276,0.0003004536,0.0001717647,0.00018634353,0.00030855156,0.00027593868,0.00040431164,0.0007581085,0.0014992345],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000029809331,0.0000034732004,0.00016731436,0.000017462959,0.0000017874463,0.00005316724,0.000007186365,0.00004307705,0.99828833,0.00045256308,0.000050522893,0.0008853698],"study_design_scores_gemma":[0.000023453375,0.000049241436,0.009665878,0.000015724872,0.000009206213,0.0010040116,0.000039902458,0.0008523756,0.97594917,0.0004558599,0.011927105,0.000008058708],"about_ca_topic_score_codex":0.00070056185,"about_ca_topic_score_gemma":0.0023113547,"teacher_disagreement_score":0.0032852571,"about_ca_system_score_codex":0.00050940405,"about_ca_system_score_gemma":0.0004264383,"threshold_uncertainty_score":0.010990262},"labels":[],"label_agreement":null},{"id":"W4400076436","doi":"10.1038/s41467-024-49552-y","title":"Structural basis for recruitment of peptidoglycan endopeptidase MepS by lipoprotein NlpI","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"College of Medicine, National Taiwan University; Academia Sinica; National Science and Technology Council; Ministry of Science and Technology, Taiwan; National Taiwan University; Public Health Agency of Canada","keywords":"Peptidoglycan; Endopeptidase; Glycan; Cell biology; Biochemistry; Plasma protein binding; Chemistry; Cell wall; Biophysics; Biology; Enzyme; Glycoprotein","score_opus":0.042601430534698205,"score_gpt":0.3439020707185522,"score_spread":0.301300640183854,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400076436","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98488706,0.0012055135,0.010520413,0.0003651375,0.000053759406,0.000035895257,0.00020071237,0.00021898358,0.0025125814],"genre_scores_gemma":[0.99426574,0.00047915557,0.0039759073,0.00009122309,0.0000094793395,0.00002276985,0.0002782804,0.000017213371,0.00086008606],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999367,0.000009449804,0.000004500978,0.000014470856,0.000020159272,0.000014673108],"domain_scores_gemma":[0.9999242,0.0000071608392,0.000024347397,0.000006828295,0.0000078449275,0.000029634806],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008639685,0.0003052712,0.00020582639,0.00008320402,0.0002838801,0.00030214697,0.0004372969,0.00049618277,0.00092098163],"category_scores_gemma":[0.00013431227,0.00017852697,0.00021641939,0.00008473191,0.00034699202,0.00026108677,0.0003222171,0.0005677227,0.00054405845],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00016271567,0.000029043702,0.0006671867,0.00006557839,0.000008877533,0.00061669183,0.000035984645,0.0013796317,0.9936761,0.002085566,0.00024264758,0.001029807],"study_design_scores_gemma":[0.00013334704,0.00031160895,0.018426608,0.000033938715,0.0000326766,0.0011085976,0.00024550423,0.06615372,0.89898866,0.002282401,0.01224047,0.00004250516],"about_ca_topic_score_codex":0.0008318349,"about_ca_topic_score_gemma":0.00071253534,"teacher_disagreement_score":0.00092098163,"about_ca_system_score_codex":0.0004738198,"about_ca_system_score_gemma":0.00036191646,"threshold_uncertainty_score":0.0034378767},"labels":[],"label_agreement":null},{"id":"W4400228883","doi":"10.5194/egusphere-2024-594-ac4","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"National Research Council Canada; Université du Québec à Montréal","funders":"","keywords":"Chemistry","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400228883","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027166234,0.0012389728,0.00023341655,0.81427014,0.16616268,0.00010020698,0.0007205468,0.00036039972,0.016641956],"genre_scores_gemma":[0.0034190866,0.0013078195,0.0002929199,0.8215116,0.07508269,0.00018880812,0.00041960002,0.00025530395,0.097522214],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977724,0.00034651184,0.00028698333,0.0003167468,0.0009070928,0.00037024246],"domain_scores_gemma":[0.9889774,0.0032874406,0.0003756762,0.0004370771,0.005018299,0.0019040377],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0028047469,0.00070711185,0.00091670227,0.0011882087,0.0025428724,0.0030209608,0.0022731847,0.02152885,0.12708883],"category_scores_gemma":[0.03236005,0.00043773543,0.0009823219,0.00082365447,0.0017438054,0.003038017,0.0019848412,0.014803396,0.0715116],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000012693263,0.000003278894,0.000056289682,0.000015488406,0.0000011384934,0.00006980569,0.000009427579,0.0000048515367,0.00002037682,0.00022093268,0.9976336,0.0019521605],"study_design_scores_gemma":[0.000015173912,0.0000099874605,0.00034040146,0.00006880565,0.0000032495304,0.00011447433,0.000069978756,0.000036846086,0.00007697796,0.0005637524,0.998684,0.000016408132],"about_ca_topic_score_codex":0.009815331,"about_ca_topic_score_gemma":0.012221158,"teacher_disagreement_score":0.87291116,"about_ca_system_score_codex":0.0035615205,"about_ca_system_score_gemma":0.0039132084,"threshold_uncertainty_score":0.4251545},"labels":[],"label_agreement":null},{"id":"W4400514261","doi":"10.1007/s12015-024-10759-7","title":"Autotaxin Inhibition Reduces Post‐Ischemic Myocardial Inflammation via Epigenetic Gene Modifications","year":2024,"lang":"en","type":"article","venue":"Stem Cell Reviews and Reports","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Canadian Heart Research Centre; University of Saskatchewan","funders":"NHLBI Division of Intramural Research; Veterans Medical Research Foundation","keywords":"Autotaxin; Inflammation; Epigenetics; Medicine; Gene; Biology; Bioinformatics; Neuroscience; Cell biology; Internal medicine; Genetics; Lysophosphatidic acid; Receptor","score_opus":0.012379641020843535,"score_gpt":0.24465303594533067,"score_spread":0.23227339492448712,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400514261","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9848179,0.0051739602,0.004884463,0.00042558167,0.0002973688,0.000048915943,0.0004121884,0.00034128243,0.0035984148],"genre_scores_gemma":[0.99142003,0.0028099618,0.0010661919,0.0001553431,0.000047069832,0.000050300147,0.00024953333,0.000033525535,0.004168035],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992824,0.0000093607905,0.0000051045927,0.000017421493,0.000016151247,0.000023811877],"domain_scores_gemma":[0.99994767,0.000008094991,0.000019102721,0.0000082671695,0.0000051391244,0.000011818481],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011463194,0.00032229206,0.0003285041,0.00014885991,0.00012862757,0.00026151576,0.00020630422,0.00023616214,0.0024782373],"category_scores_gemma":[0.00009131793,0.00012246643,0.00020199957,0.000097349795,0.00030135785,0.00018272796,0.00013913128,0.00083259697,0.00030811914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007575827,0.00011054598,0.00012909205,0.000070981165,0.000021235273,0.0000459039,0.0000147016435,0.00011212578,0.990602,0.0003515031,0.00025363857,0.007530652],"study_design_scores_gemma":[0.00023394082,0.0015652722,0.0065993913,0.000014452778,0.00009833345,0.00015698512,0.000048688802,0.0006870987,0.9838037,0.00029589227,0.0064829625,0.000013208854],"about_ca_topic_score_codex":0.0003128445,"about_ca_topic_score_gemma":0.0010009663,"teacher_disagreement_score":0.0024782373,"about_ca_system_score_codex":0.00016679538,"about_ca_system_score_gemma":0.00019078043,"threshold_uncertainty_score":0.008290529},"labels":[],"label_agreement":null},{"id":"W4400525722","doi":"10.5194/egusphere-2024-971-ac4","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Chemistry; Materials science; Environmental science; Mineralogy","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4400525722","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002442807,0.0016642129,0.00024630138,0.6951957,0.25739723,0.00013039989,0.0006921086,0.00062154804,0.043808173],"genre_scores_gemma":[0.0024137157,0.0010555121,0.00023016751,0.7421483,0.08346337,0.00016965823,0.00034698384,0.00024133358,0.16993102],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99847716,0.00026404235,0.00016004658,0.00027276922,0.00056870974,0.00025725004],"domain_scores_gemma":[0.9947672,0.0015457844,0.00023567666,0.0002810214,0.0021293247,0.0010410459],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0016976319,0.000895809,0.0009705672,0.0011660903,0.002575999,0.003386523,0.0027609027,0.021420542,0.2310145],"category_scores_gemma":[0.017885186,0.0005286555,0.001184865,0.00080851803,0.0017645749,0.0034288855,0.0026060133,0.017271422,0.14278683],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008079911,0.0000027576612,0.000027793203,0.000012005736,8.1664695e-7,0.0000531523,0.000005732564,0.0000032692835,0.000015757196,0.00017280589,0.99776125,0.0019366015],"study_design_scores_gemma":[0.000012548375,0.000008272601,0.00020635796,0.000060328894,0.0000021148824,0.00009440785,0.000055344703,0.000026983993,0.00004836264,0.00047999708,0.99899524,0.000009956674],"about_ca_topic_score_codex":0.005676469,"about_ca_topic_score_gemma":0.007863039,"teacher_disagreement_score":0.7689855,"about_ca_system_score_codex":0.0028364921,"about_ca_system_score_gemma":0.0024117185,"threshold_uncertainty_score":0.7728205},"labels":[],"label_agreement":null},{"id":"W4401456184","doi":"10.5194/egusphere-2024-925-ac1","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Environmental science","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4401456184","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029349056,0.0019295062,0.000291193,0.64022315,0.28698143,0.00018768075,0.0013699228,0.0007653826,0.067958206],"genre_scores_gemma":[0.0028443343,0.0012710142,0.00024186906,0.6497126,0.08760547,0.00021749023,0.0006235955,0.00030703537,0.25717658],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998451,0.00025382527,0.00017065596,0.0002628516,0.00057273987,0.00028892726],"domain_scores_gemma":[0.99511343,0.0015573398,0.00019546668,0.0002508779,0.0019804377,0.00090238743],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0018466226,0.0008192413,0.0009055596,0.0011059216,0.0024363513,0.0032409255,0.0023975724,0.017994959,0.29154554],"category_scores_gemma":[0.019622076,0.0004816451,0.0012736425,0.0007314633,0.0014700958,0.0028346963,0.0023354036,0.015135787,0.1833612],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011274679,0.0000033355966,0.00003036228,0.0000129004,8.153428e-7,0.00004648059,0.0000055347737,0.0000038899834,0.0000142441595,0.00021620399,0.9973713,0.002283712],"study_design_scores_gemma":[0.000015789548,0.00000860174,0.00021001055,0.000063966276,0.000002146798,0.000072359515,0.000045594727,0.000026852165,0.000047447156,0.0004440396,0.999054,0.000009186217],"about_ca_topic_score_codex":0.0061821025,"about_ca_topic_score_gemma":0.0081871515,"teacher_disagreement_score":0.7084545,"about_ca_system_score_codex":0.0025895159,"about_ca_system_score_gemma":0.0023008413,"threshold_uncertainty_score":0.975317},"labels":[],"label_agreement":null},{"id":"W4402041595","doi":"10.1016/j.str.2024.08.007","title":"Structure of calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A","year":2024,"lang":"en","type":"article","venue":"Structure","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria; University of British Columbia","funders":"British Columbia Knowledge Development Fund; Natural Sciences and Engineering Research Council of Canada; Novartis; Canadian Institutes of Health Research; University of British Columbia; Canada Foundation for Innovation; Michael Smith Health Research BC","keywords":"Calcineurin; Phosphatase; Phosphatidylinositol; Cell biology; Biology; Plasma protein binding; Biochemistry; Phosphorylation; Chemistry","score_opus":0.006699535980254664,"score_gpt":0.2754570779179732,"score_spread":0.2687575419377185,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402041595","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9882414,0.0017720724,0.0036771493,0.0011625752,0.00016899777,0.000031254258,0.00066234305,0.00039259784,0.0038916294],"genre_scores_gemma":[0.9914454,0.0006629568,0.0033439347,0.00024146232,0.000018469866,0.000017052975,0.0014127629,0.000044143726,0.0028139115],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998617,0.000015890024,0.000008132782,0.00003502855,0.00004107734,0.00003811488],"domain_scores_gemma":[0.99975044,0.00005369983,0.000078940415,0.000014847566,0.000023643828,0.00007848379],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019973294,0.00053470436,0.0005594213,0.00028382574,0.00089498097,0.000621833,0.00095485314,0.0015237551,0.0036569021],"category_scores_gemma":[0.00045394708,0.00028913797,0.0005022192,0.00037792334,0.0005785258,0.0006558013,0.00042641166,0.0019915295,0.0004356638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0038251248,0.00036429943,0.006764105,0.0006993055,0.00023044794,0.006758837,0.0008412154,0.011094951,0.9401928,0.0082933735,0.0077079255,0.013227608],"study_design_scores_gemma":[0.001494257,0.0016226249,0.1358096,0.00036667194,0.00047785838,0.013581266,0.0017208899,0.19142994,0.5818799,0.007035326,0.0639084,0.00067333976],"about_ca_topic_score_codex":0.008623225,"about_ca_topic_score_gemma":0.006491624,"teacher_disagreement_score":0.008623225,"about_ca_system_score_codex":0.0017707928,"about_ca_system_score_gemma":0.0008326482,"threshold_uncertainty_score":0.01714605},"labels":[],"label_agreement":null},{"id":"W4402253859","doi":"10.21203/rs.3.rs-5005208/v1","title":"Molecular dynamic simulation of Cyclophilin A in complex with Sanglifehrin A","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Cyclophilin; Cyclophilin A; Molecular dynamics; Epistemology; Computer science; Chemistry; Philosophy; Biology; Computational chemistry; Biochemistry","score_opus":0.04513522143637009,"score_gpt":0.40803308991446996,"score_spread":0.36289786847809985,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402253859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98484147,0.0001976041,0.0036216709,0.0008448924,0.000108871725,0.000031117284,0.0007456896,0.00023928047,0.00936943],"genre_scores_gemma":[0.99630046,0.00013584655,0.0015122959,0.0001087661,0.000024244106,0.0000506067,0.00055692357,0.00007477744,0.0012361772],"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9998079,0.000025408695,0.0000057477423,0.00003585983,0.000036662324,0.000088473025],"domain_scores_gemma":[0.9993467,0.00036627994,0.00004588398,0.00004344183,0.000066556226,0.00013118597],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00026757718,0.0007347871,0.0009669836,0.0005978947,0.0017813346,0.0011162838,0.001615882,0.0016344913,0.014202864],"category_scores_gemma":[0.0009118779,0.0005977813,0.0007718895,0.00066973205,0.0010934991,0.0010482325,0.00059496827,0.0015645362,0.0004972974],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006241873,0.00054210814,0.0043683043,0.00014931116,0.00019428584,0.000723742,0.00028156175,0.9647061,0.012667162,0.010237931,0.0029144632,0.0025908127],"study_design_scores_gemma":[0.00009169542,0.00007072752,0.0008333615,0.000007255805,0.000016799002,0.000016964797,0.000072695504,0.99616325,0.0013391922,0.00090746366,0.0004650485,0.000015485532],"about_ca_topic_score_codex":0.023225298,"about_ca_topic_score_gemma":0.013060505,"teacher_disagreement_score":0.023225298,"about_ca_system_score_codex":0.0023392765,"about_ca_system_score_gemma":0.0014748155,"threshold_uncertainty_score":0.047513306},"labels":[],"label_agreement":null},{"id":"W4402646227","doi":"10.5194/egusphere-2024-2502-cc2","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Geoscience BC; University of British Columbia","funders":"","keywords":"Materials science","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402646227","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00050027075,0.0012899986,0.0003823443,0.7334874,0.16721936,0.0003649973,0.0016448713,0.00081582565,0.09429485],"genre_scores_gemma":[0.0039984128,0.0009105822,0.00032484796,0.54504526,0.03936813,0.00034479433,0.00067456294,0.00039862117,0.4089348],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979488,0.00034748783,0.00020011775,0.00024757715,0.0008851404,0.0003708897],"domain_scores_gemma":[0.9890838,0.0025619585,0.0003063046,0.00039163136,0.005841089,0.0018152328],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002088163,0.0007391988,0.0007503523,0.0012565074,0.0035733618,0.0031802729,0.0017352997,0.014547216,0.30111352],"category_scores_gemma":[0.025690401,0.00038091734,0.00081466394,0.0009273323,0.0014877418,0.0030229161,0.002526703,0.01010917,0.1607104],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000006402466,0.0000023711752,0.000039009254,0.000011752994,5.107323e-7,0.00003505692,0.000012380378,0.0000022572397,0.000014895155,0.00013975493,0.99818856,0.0015470738],"study_design_scores_gemma":[0.0000071326285,0.0000067289166,0.00027930713,0.00005357641,0.0000016049723,0.000051333136,0.00013527575,0.000017948381,0.00004726212,0.00026851048,0.9991215,0.000009798063],"about_ca_topic_score_codex":0.01709042,"about_ca_topic_score_gemma":0.023704562,"teacher_disagreement_score":0.30111352,"about_ca_system_score_codex":0.0040436466,"about_ca_system_score_gemma":0.003970991,"threshold_uncertainty_score":0.9968768},"labels":[],"label_agreement":null},{"id":"W4402672762","doi":"10.5194/egusphere-2024-800-ac3","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402672762","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0002984571,0.0018808381,0.0004536266,0.4585235,0.33279917,0.00036642698,0.0038550394,0.0014885594,0.20033436],"genre_scores_gemma":[0.0024350144,0.0011543264,0.00029885673,0.38497555,0.07462648,0.00036529792,0.0014817342,0.00062844716,0.5340342],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977991,0.00031315302,0.00021488813,0.00037197597,0.00085335475,0.00044752756],"domain_scores_gemma":[0.994391,0.0014293394,0.00020112013,0.00041792294,0.0026493783,0.00091114733],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0023287714,0.0009269552,0.0010497121,0.0011874744,0.0028373203,0.00442043,0.0025991944,0.016772896,0.46171692],"category_scores_gemma":[0.02050514,0.00055623625,0.0014926433,0.00093565497,0.0015261016,0.0028827419,0.0025835999,0.012081055,0.35582203],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008629785,0.0000028231136,0.000016824746,0.000012170854,6.8562747e-7,0.000019616375,0.0000035627854,0.000002847715,0.000013271862,0.00025334384,0.9976404,0.0020259025],"study_design_scores_gemma":[0.000014793762,0.0000072242474,0.00017694313,0.00005554371,0.0000015680821,0.000024544423,0.00002622671,0.000017692782,0.000041716045,0.00037617626,0.9992513,0.000006297142],"about_ca_topic_score_codex":0.007564694,"about_ca_topic_score_gemma":0.008856165,"teacher_disagreement_score":0.46171692,"about_ca_system_score_codex":0.003134846,"about_ca_system_score_gemma":0.0029746366,"threshold_uncertainty_score":0.76779544},"labels":[],"label_agreement":null},{"id":"W4402746363","doi":"10.5194/egusphere-2024-2679-cc2","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Queen's University; McGill University","funders":"","keywords":"Environmental science","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402746363","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00028041375,0.0016987141,0.0002910466,0.65574706,0.27365264,0.00017592164,0.0011706492,0.00067890814,0.06630465],"genre_scores_gemma":[0.0032212501,0.001179521,0.00027529593,0.658966,0.09330809,0.00024326438,0.0005380236,0.00031731048,0.24195127],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.998415,0.0002519728,0.0001641311,0.00027772042,0.0005982137,0.00029291803],"domain_scores_gemma":[0.9951421,0.001348285,0.00020918822,0.00031445455,0.0020446978,0.0009413107],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0017532961,0.00083761377,0.0009243948,0.001002372,0.0024317224,0.0033587501,0.0023945589,0.019815292,0.2754601],"category_scores_gemma":[0.017356265,0.00046048145,0.0011415156,0.0007842544,0.001713691,0.0029247135,0.0023785457,0.015293151,0.16468251],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010185074,0.0000028662832,0.000030237934,0.000012361219,9.025623e-7,0.000039329567,0.0000046389996,0.0000035771427,0.000015326601,0.00019591856,0.9975243,0.0021603773],"study_design_scores_gemma":[0.000012513717,0.000007704141,0.00022897137,0.000052041774,0.0000019243864,0.000056239405,0.000043991313,0.000024154242,0.000052777898,0.0004382748,0.99907315,0.000008291382],"about_ca_topic_score_codex":0.006132062,"about_ca_topic_score_gemma":0.00844762,"teacher_disagreement_score":0.2754601,"about_ca_system_score_codex":0.0030480188,"about_ca_system_score_gemma":0.0023974776,"threshold_uncertainty_score":0.9215058},"labels":[],"label_agreement":null},{"id":"W4402751650","doi":"10.1093/cvr/cvae163","title":"Hypoxia-responsive zinc finger E-box-binding homeobox 2 (ZEB2) regulates a network of calcium-handling genes in the injured heart","year":2024,"lang":"en","type":"article","venue":"Cardiovascular Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Manitoba","funders":"Hartstichting; H2020 European Research Council; Fondation Leducq","keywords":"Heart failure; Homeobox; Hypoxia (environmental); Contractility; Calcium; Calcium in biology; Zinc finger; Medicine; Cardiology; Bioinformatics; Biology; Internal medicine; Gene; Chemistry; Transcription factor; Genetics","score_opus":0.06368370394366073,"score_gpt":0.35241179285594976,"score_spread":0.288728088912289,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4402751650","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98104227,0.0055436837,0.008770498,0.0003211184,0.000054950186,0.000059115424,0.001029327,0.0002288133,0.0029503077],"genre_scores_gemma":[0.98928434,0.0015548328,0.0031164347,0.0001813308,0.000019371339,0.000049791317,0.0009513154,0.000034112698,0.0048085996],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998989,0.000014841884,0.0000048947168,0.000030362511,0.000024841165,0.000026252494],"domain_scores_gemma":[0.9998976,0.000013568168,0.00004018532,0.000004988414,0.000013622207,0.000030073887],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011993651,0.0003370789,0.00021612842,0.000238169,0.0002277226,0.00025873136,0.00015153139,0.00025068125,0.0014074041],"category_scores_gemma":[0.00013188657,0.00013856872,0.00017287066,0.00018421054,0.00020623008,0.00014142065,0.00029682321,0.0003483757,0.00040299373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021195276,0.000016558368,0.0020461264,0.00006203337,0.000011335244,0.00017948357,0.000029689827,0.00010104254,0.9947994,0.00019101481,0.00018933178,0.0021619564],"study_design_scores_gemma":[0.00020016781,0.0004772758,0.19874166,0.000071413015,0.00011073404,0.0032483828,0.0003410808,0.0069417623,0.76419437,0.0007018311,0.024941785,0.000029489915],"about_ca_topic_score_codex":0.00043939287,"about_ca_topic_score_gemma":0.00054856105,"teacher_disagreement_score":0.0014074041,"about_ca_system_score_codex":0.00025633958,"about_ca_system_score_gemma":0.00015732732,"threshold_uncertainty_score":0.00470829},"labels":[],"label_agreement":null},{"id":"W4403818136","doi":"10.1093/eurheartj/ehae666.3775","title":"Calcitonin signalling system regulates function and arhythmogenicity of atrial cardiomyocytes","year":2024,"lang":"en","type":"article","venue":"European Heart Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Montreal Heart Institute","funders":"","keywords":"Medicine; Internal medicine; Cardiology; Calcitonin; Endocrinology; Function (biology); Cell biology","score_opus":0.01995240101259828,"score_gpt":0.25536138942745373,"score_spread":0.23540898841485544,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4403818136","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99218994,0.0041957223,0.0013535274,0.0001424568,0.00003984294,0.000019015972,0.00043657867,0.000057991703,0.0015648394],"genre_scores_gemma":[0.99740064,0.0010549059,0.0004672237,0.00005341633,0.000015839729,0.000024566718,0.00023993434,0.0000076837505,0.00073578564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99983215,0.000021193337,0.000018013981,0.00004270406,0.000043105952,0.00004273234],"domain_scores_gemma":[0.99989367,0.000018538445,0.000029008952,0.000009443532,0.000012708922,0.000036578404],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013300794,0.00019782795,0.00020158457,0.00024837427,0.00013312264,0.00035749134,0.00012097394,0.0002658075,0.0013134092],"category_scores_gemma":[0.00015519992,0.00008236007,0.00018278808,0.00014530313,0.0002457122,0.0001847858,0.0002168753,0.00037861697,0.0002249174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013404268,0.0000144323185,0.0010783047,0.000036193684,0.0000061003257,0.000105593885,0.000022694594,0.00003346915,0.99699426,0.000058703336,0.000042366868,0.0014738664],"study_design_scores_gemma":[0.00007554444,0.0012473175,0.26234388,0.00005212758,0.00010405794,0.002189117,0.0004244276,0.004314894,0.7228756,0.0007346054,0.005601307,0.000036975973],"about_ca_topic_score_codex":0.00028624813,"about_ca_topic_score_gemma":0.00025315612,"teacher_disagreement_score":0.0013134092,"about_ca_system_score_codex":0.00016665198,"about_ca_system_score_gemma":0.00015062327,"threshold_uncertainty_score":0.004393816},"labels":[],"label_agreement":null},{"id":"W4404041923","doi":"10.1021/acs.jmedchem.4c02010","title":"A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins","year":2024,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Princess Margaret Cancer Centre; Structural Genomics Consortium; York University; University of Toronto","funders":"National Institute of General Medical Sciences; Bristol-Myers Squibb Canada; Genentech; Innovative Medicines Initiative; Ontario Genomics Institute; University of Toronto; European Federation of Pharmaceutical Industries and Associations; Structural Genomics Consortium; Merck KGaA; National Institutes of Health; Ontario Genomics; Office of Research Infrastructure Programs, National Institutes of Health; Genome Canada; Bayer; Pfizer; Bristol-Myers Squibb; Takeda Canada; McGill University; Office of Science; Boehringer Ingelheim; Argonne National Laboratory; Janssen Canada; U.S. Department of Energy","keywords":"Chemistry; Biochemistry; Class (philosophy); Computational biology; Artificial intelligence","score_opus":0.020956002137195645,"score_gpt":0.3105981294356083,"score_spread":0.28964212729841265,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404041923","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97806495,0.0027704171,0.011747058,0.00013841178,0.000019305282,0.00037113577,0.0016234214,0.0003873807,0.0048778155],"genre_scores_gemma":[0.9830952,0.0015481566,0.010536323,0.00014569092,0.000015023606,0.00018692588,0.0022280354,0.000055708737,0.0021889508],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9992687,0.0001793856,0.000062321276,0.0001292013,0.00027342187,0.00008705499],"domain_scores_gemma":[0.99939966,0.00023757556,0.000088103036,0.00005710591,0.00015842478,0.000059069596],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014036607,0.0005069374,0.00072924816,0.0009973794,0.00039742596,0.00048904505,0.0003329091,0.00027418215,0.0022832311],"category_scores_gemma":[0.0014888233,0.00015071694,0.0003356703,0.0007038282,0.00030251592,0.00050697,0.0005941993,0.00037906552,0.00040859196],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007976639,0.00048352528,0.003424203,0.00017902248,0.00009065965,0.00011946105,0.00004683626,0.0056115994,0.9339214,0.0002858821,0.0003293024,0.054710463],"study_design_scores_gemma":[0.000093418836,0.009096736,0.00877259,0.000020567437,0.00019683383,0.0008567392,0.000077774515,0.011128215,0.9634486,0.00026203404,0.006002526,0.000044033175],"about_ca_topic_score_codex":0.00090915384,"about_ca_topic_score_gemma":0.0012803802,"teacher_disagreement_score":0.0022832311,"about_ca_system_score_codex":0.00046489565,"about_ca_system_score_gemma":0.00042329865,"threshold_uncertainty_score":0.007638216},"labels":[],"label_agreement":null},{"id":"W4404078053","doi":"10.5194/egusphere-2024-871-ac1","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Simon Fraser University","funders":"","keywords":"Environmental science","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404078053","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00040750363,0.0015437017,0.00035459307,0.7065733,0.20717849,0.00027413896,0.0016460358,0.00091112417,0.08111104],"genre_scores_gemma":[0.0035910627,0.00085881026,0.0002782951,0.6925145,0.051266845,0.00031288233,0.0005994741,0.00038456937,0.2501936],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977695,0.00039919448,0.00023538688,0.0003461772,0.0008114534,0.00043840034],"domain_scores_gemma":[0.9925904,0.0022346203,0.00026425815,0.0004037965,0.0033765242,0.00113039],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0023591928,0.00089765625,0.0010059145,0.0012608598,0.003158968,0.0040388927,0.0026934454,0.02221282,0.2766371],"category_scores_gemma":[0.02570508,0.00051137217,0.0012962667,0.00095889915,0.0017297816,0.0031035068,0.0025623182,0.015604714,0.17264614],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000113469905,0.0000037018317,0.000036737863,0.000014088307,9.241976e-7,0.000042872052,0.0000081934,0.0000042718493,0.00001814595,0.00026086782,0.99762124,0.0019776053],"study_design_scores_gemma":[0.000013285171,0.000009403176,0.00024143021,0.000062372994,0.0000022158238,0.00005948013,0.000060704315,0.000035620804,0.0000619713,0.00051646074,0.9989266,0.000010437331],"about_ca_topic_score_codex":0.0076878075,"about_ca_topic_score_gemma":0.008993121,"teacher_disagreement_score":0.7233629,"about_ca_system_score_codex":0.0036259242,"about_ca_system_score_gemma":0.0031129152,"threshold_uncertainty_score":0.9254433},"labels":[],"label_agreement":null},{"id":"W4404167794","doi":"10.1016/j.bbadis.2024.167565","title":"GPR68 supports AML cells through the calcium/calcineurin pro-survival pathway and confers chemoresistance by mediating glucose metabolic symbiosis","year":2024,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; Yale School of Management; Tufts University School of Medicine; Scripps Research Institute; Office of the Vice President for Research and Partnerships; School of Medicine, University of South Carolina; University of South Carolina; St. Baldrick's Foundation; International OCD Foundation; National Institutes of Health; Aplastic Anemia and Myelodysplasia Association of Canada; National Science Foundation; Cincinnati Children's Hospital Medical Center; Foundation for the National Institutes of Health","keywords":"Calcineurin; Metabolic pathway; Calcium; Biology; Cell biology; Cancer research; Internal medicine; Endocrinology; Metabolism; Medicine; Transplantation","score_opus":0.010454039012193155,"score_gpt":0.25621887733176457,"score_spread":0.2457648383195714,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404167794","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9956897,0.00073509564,0.0009547112,0.00038996706,0.000052771145,0.000018203265,0.00025323458,0.00011418293,0.0017920464],"genre_scores_gemma":[0.9976641,0.00024604105,0.00035645496,0.000069163776,0.0000138168425,0.000014288837,0.0002063428,0.000011811715,0.0014180556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997322,0.000048835063,0.000021994229,0.00003140952,0.000067860354,0.00009771452],"domain_scores_gemma":[0.9998745,0.000015485697,0.000027979242,0.000021736709,0.000014153548,0.00004603535],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014413214,0.00023227808,0.00027295627,0.0002880086,0.000244632,0.00043120913,0.00021134966,0.00031532536,0.0028010816],"category_scores_gemma":[0.0002018059,0.00012596571,0.00020374086,0.00018844943,0.0002646415,0.00025270638,0.0004099354,0.00084304955,0.0006836405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00042662444,0.000079489,0.00057593675,0.0000461048,0.000006563987,0.00016001529,0.000040428775,0.00005940129,0.9949431,0.0004028059,0.00025317358,0.003006392],"study_design_scores_gemma":[0.00017028743,0.0008710812,0.00968841,0.00001040247,0.00004694047,0.0012508294,0.00023733017,0.0014634196,0.972327,0.00029693672,0.013624911,0.000012515923],"about_ca_topic_score_codex":0.00071246165,"about_ca_topic_score_gemma":0.00081560685,"teacher_disagreement_score":0.0028010816,"about_ca_system_score_codex":0.0001868939,"about_ca_system_score_gemma":0.00024228088,"threshold_uncertainty_score":0.009370565},"labels":[],"label_agreement":null},{"id":"W4404230748","doi":"10.1093/neuonc/noae165.1252","title":"TMIC-75. ICAM-1 PROMOTES AN IMMUNOSUPPRESSIVE LANDSCAPE IN GLIOBLASTOMAS BY REGULATING THE PHENOTYPIC POLARIZATION STATE OF TUMOR ASSOCIATED MACROPHAGES","year":2024,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; Toronto Western Hospital; Princess Margaret Cancer Centre","funders":"","keywords":"Phenotype; ICAM-1; Glioblastoma; Cancer research; Polarization (electrochemistry); Biology; Immunology; Chemistry; Genetics; Gene; Cell adhesion molecule","score_opus":0.007259614208771409,"score_gpt":0.25993952079567284,"score_spread":0.2526799065869014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404230748","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9966383,0.00091671164,0.00030496516,0.00011390065,0.000038032784,0.00001881955,0.00030636904,0.000052399417,0.0016104372],"genre_scores_gemma":[0.9973115,0.00038923477,0.00024429458,0.00009763832,0.000010629812,0.000022101927,0.00032958685,0.000006938052,0.0015882739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999897,0.0000060473453,0.0000047724384,0.0000117272,0.000018024533,0.00006244646],"domain_scores_gemma":[0.9999615,0.0000021342191,0.0000062732734,0.0000028075247,0.000003417365,0.00002374636],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000051575185,0.00025943067,0.00019977636,0.00021683642,0.00016922169,0.00024025542,0.000109342574,0.00016605256,0.0013292832],"category_scores_gemma":[0.000035664176,0.00006935206,0.00014569702,0.00012314304,0.0001914753,0.000086149295,0.00011464386,0.00047283032,0.00042182635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015058606,0.00007577982,0.00027311072,0.000033520242,0.000003557435,0.000049011327,0.000013344206,0.000050871797,0.9976035,0.00009504501,0.00018145256,0.0014702249],"study_design_scores_gemma":[0.000098147015,0.0022130103,0.043652523,0.00002294625,0.000053193682,0.00041749072,0.00020393301,0.0011026056,0.94508135,0.00016599476,0.006976951,0.000011932682],"about_ca_topic_score_codex":0.0012963451,"about_ca_topic_score_gemma":0.002170934,"teacher_disagreement_score":0.0013292832,"about_ca_system_score_codex":0.0002558083,"about_ca_system_score_gemma":0.00024323333,"threshold_uncertainty_score":0.004446864},"labels":[],"label_agreement":null},{"id":"W4404363692","doi":"10.1161/circ.150.suppl_1.4140244","title":"Abstract 4140244: In a Murine Model of Experimental Sepsis, Cardiac-Specific Jarid2 Knockdown is Associated With Improved Myocardial Function and Survival","year":2024,"lang":"en","type":"article","venue":"Circulation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Medicine; Gene knockdown; Cardiac function curve; Cardiology; Sepsis; Internal medicine; Heart failure; Genetics; Gene","score_opus":0.017704029271736862,"score_gpt":0.242928349910155,"score_spread":0.22522432063841813,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404363692","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9678831,0.00575228,0.01013302,0.0012946585,0.00070647546,0.0002093039,0.0078013297,0.0010227995,0.005197101],"genre_scores_gemma":[0.9557036,0.0032388896,0.009988738,0.00062510703,0.00019206939,0.00050379493,0.007859492,0.00027066606,0.021617653],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997309,0.000023829372,0.000036927337,0.000078009834,0.00007656302,0.000053793297],"domain_scores_gemma":[0.99973136,0.000020057952,0.00009911569,0.000018971226,0.000024569144,0.00010584743],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022157225,0.0008262249,0.00065887166,0.0004362265,0.0003337675,0.00047018772,0.00036108782,0.0007333052,0.0058823987],"category_scores_gemma":[0.00011477139,0.00031130807,0.00039881124,0.00023960324,0.00048599218,0.00045997975,0.00030557578,0.0014718341,0.0014709508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004603335,0.00007995015,0.00010905371,0.000134101,0.000008712818,0.00006460467,0.00001385619,0.00003742442,0.9978619,0.00008274466,0.0002448636,0.0009024706],"study_design_scores_gemma":[0.00021040186,0.0016797216,0.0045271544,0.000037759473,0.000058510523,0.0007157734,0.00006308126,0.000807578,0.9854382,0.0000963663,0.0063503576,0.000015074843],"about_ca_topic_score_codex":0.00029038446,"about_ca_topic_score_gemma":0.00041189112,"teacher_disagreement_score":0.0058823987,"about_ca_system_score_codex":0.00029224085,"about_ca_system_score_gemma":0.00027038762,"threshold_uncertainty_score":0.019678652},"labels":[],"label_agreement":null},{"id":"W4404902422","doi":"10.1038/s41401-024-01424-3","title":"Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction","year":2024,"lang":"en","type":"article","venue":"Acta Pharmacologica Sinica","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Lawson Health Research Institute; London Health Sciences Centre; Western University","funders":"","keywords":"Nicotinamide mononucleotide; Mitochondrial permeability transition pore; MPTP; Sepsis; Septic shock; NAD+ kinase; Pharmacology; Nicotinamide; Medicine; Chemistry; Internal medicine; Endocrinology; Nicotinamide adenine dinucleotide; Immunology; Programmed cell death; Biochemistry; Enzyme; Apoptosis; Disease","score_opus":0.019970145568378464,"score_gpt":0.2978717012193917,"score_spread":0.27790155565101327,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404902422","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99064106,0.0034531634,0.0023517995,0.00049397926,0.00015252107,0.000059546277,0.00043538716,0.00024848364,0.0021639199],"genre_scores_gemma":[0.99036366,0.0024651156,0.0014907942,0.00013069456,0.000028321534,0.00008107708,0.00028989027,0.000026838776,0.005123626],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991727,0.000014923057,0.000007692229,0.000019365873,0.00001527128,0.000025440038],"domain_scores_gemma":[0.9998832,0.0000073059678,0.00004385057,0.000014595146,0.000010644588,0.00004047296],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00014438345,0.0005535455,0.00033768069,0.00038609045,0.00022022554,0.00025464952,0.00034719714,0.00058899546,0.001897292],"category_scores_gemma":[0.000097292635,0.00022134949,0.00024677152,0.00013110304,0.00039773257,0.00023790324,0.0001722477,0.0008917447,0.000341235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020080006,0.00012804841,0.00027106248,0.000056788478,0.000022034166,0.00011261504,0.000013972042,0.0000721492,0.9942027,0.0002479352,0.00008907113,0.0027755129],"study_design_scores_gemma":[0.00038883765,0.001920859,0.0060076443,0.000025627407,0.00010369947,0.00031639874,0.00007893029,0.0007959059,0.9874506,0.0002877005,0.0026115275,0.000012334756],"about_ca_topic_score_codex":0.00094375544,"about_ca_topic_score_gemma":0.0018859851,"teacher_disagreement_score":0.001897292,"about_ca_system_score_codex":0.0002820139,"about_ca_system_score_gemma":0.00042666684,"threshold_uncertainty_score":0.00634712},"labels":[],"label_agreement":null},{"id":"W4405123958","doi":"10.5194/hess-2024-292-cc2","title":"Reply on CC1","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Global Institute for Water Security; University of Saskatchewan","funders":"","keywords":"Chemistry","score_opus":0.027367004551241563,"score_gpt":0.32030295214398125,"score_spread":0.29293594759273966,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405123958","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034484148,0.0019995691,0.0004121892,0.7129335,0.2250793,0.00017758665,0.0013064657,0.0006824896,0.057064045],"genre_scores_gemma":[0.003423705,0.0012721729,0.00031987778,0.7500094,0.061151866,0.00021156344,0.00056118617,0.00033006925,0.18272007],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983462,0.00028320035,0.0001747786,0.0003016881,0.0005886249,0.0003054828],"domain_scores_gemma":[0.9946483,0.0014842327,0.00018666021,0.00026345262,0.0024929754,0.0009244639],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019281391,0.00079192646,0.000838911,0.0010129074,0.0024183393,0.003308988,0.0023697894,0.018373301,0.23071888],"category_scores_gemma":[0.021468198,0.0004152061,0.0011956106,0.0007073656,0.0015381376,0.0033181263,0.0023095566,0.015318087,0.13486364],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009769872,0.0000028565203,0.00003418359,0.000012568283,9.777183e-7,0.000051135965,0.0000073272818,0.00000420583,0.000016492015,0.00028303094,0.9971517,0.0024257626],"study_design_scores_gemma":[0.000012184735,0.000008695805,0.0001860682,0.00006273747,0.0000024610122,0.00010357696,0.00005887449,0.000031574917,0.0000668093,0.00059326855,0.99886405,0.000009734624],"about_ca_topic_score_codex":0.0060898107,"about_ca_topic_score_gemma":0.007264896,"teacher_disagreement_score":0.23071888,"about_ca_system_score_codex":0.0029022538,"about_ca_system_score_gemma":0.0027827688,"threshold_uncertainty_score":0.7718315},"labels":[],"label_agreement":null},{"id":"W4405940725","doi":"10.1073/pnas.2419883121","title":"Structure-guided design and synthesis of C22- and C32-modified FK520 analogs with enhanced activity against human pathogenic fungi","year":2024,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Science Foundation Graduate Research Fellowship Program; National Institute of General Medical Sciences; Canadian Institute for Advanced Research; National Institutes of Health; National Science Foundation","keywords":"Chemistry; Combinatorial chemistry","score_opus":0.03549687481012414,"score_gpt":0.30070528336069796,"score_spread":0.2652084085505738,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4405940725","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98056245,0.0030411186,0.009474624,0.00020975774,0.0000593738,0.0003667413,0.00075349386,0.00017497341,0.0053575523],"genre_scores_gemma":[0.98736507,0.0019435536,0.007720585,0.00011451295,0.000009038824,0.00010119427,0.0006989577,0.000024514531,0.0020225735],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999206,0.000012056184,0.000008720825,0.000015715863,0.000014609967,0.000028238768],"domain_scores_gemma":[0.9999547,0.000004334835,0.000011906044,0.0000043042933,0.000009038787,0.000015674967],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015234329,0.00048567634,0.00031671367,0.00019844837,0.00014636652,0.00021487218,0.00037033908,0.00026116119,0.001507323],"category_scores_gemma":[0.00016394407,0.00014446717,0.00024973444,0.0002106849,0.0001530814,0.00019285224,0.00021554026,0.0003504259,0.00043049248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00086739106,0.0002883666,0.0003065612,0.00025294983,0.000040628744,0.00040947672,0.000063244996,0.0123155285,0.9636881,0.0011291797,0.0006963916,0.019942172],"study_design_scores_gemma":[0.00067741383,0.005096971,0.0022798902,0.00005434208,0.00011649965,0.00061720243,0.00006671465,0.013996393,0.9618316,0.0002993938,0.014891626,0.00007195381],"about_ca_topic_score_codex":0.0010956174,"about_ca_topic_score_gemma":0.0018375874,"teacher_disagreement_score":0.001507323,"about_ca_system_score_codex":0.00037516595,"about_ca_system_score_gemma":0.00031588742,"threshold_uncertainty_score":0.0050424337},"labels":[],"label_agreement":null},{"id":"W4406097056","doi":"10.12688/f1000research.160371.1","title":"A guide to selecting high-performing antibodies for TAF15 (UniProt ID: Q92804) for use in western blot, immunoprecipitation, and immunofluorescence","year":2025,"lang":"en","type":"preprint","venue":"F1000Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"Genentech; Mitacs; Motor Neurone Disease Association; Government of Canada; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Ontario Genomics Institute; Génome Québec; Bayer; ALS Society of Canada; Ontario Genomics; Genome Canada; Bristol-Myers Squibb; Pfizer; ALS Association","keywords":"Immunoprecipitation; Western blot; UniProt; Immunofluorescence; Open peer review; Plant biology; Antibody; Biology; Computational biology; Blot; Medicine; Immunology; Genetics; Gene; Botany","score_opus":0.03824863310581102,"score_gpt":0.3737576350426341,"score_spread":0.3355090019368231,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406097056","genre_codex":"methods","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":"methods","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0074723833,0.013607307,0.60778135,0.0042112526,0.003012235,0.006064479,0.18589869,0.10862719,0.06332514],"genre_scores_gemma":[0.006258833,0.007786533,0.7213034,0.0017254036,0.0005214008,0.010665337,0.18015164,0.025120413,0.046466984],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99654835,0.0008630029,0.0006538524,0.0005009155,0.0011059376,0.00032804604],"domain_scores_gemma":[0.99469995,0.0017500323,0.00031387812,0.0013178618,0.0014701152,0.00044812294],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005513503,0.004045412,0.0036860416,0.0066487105,0.0024063338,0.0027835353,0.0053696465,0.0032118917,0.15429728],"category_scores_gemma":[0.010243476,0.0053627235,0.0020459197,0.004410327,0.0009374999,0.0022737375,0.0020466284,0.005042124,0.24268006],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00070053124,0.00025256517,0.00064681936,0.0031066877,0.00013516177,0.0006414067,0.00026619996,0.000539611,0.24185735,0.0036961008,0.6466101,0.10154751],"study_design_scores_gemma":[0.00018957468,0.00014554324,0.0019070564,0.0003937904,0.00007292741,0.0015620803,0.000057699188,0.00085073523,0.048378315,0.0026009644,0.94374293,0.00009834573],"about_ca_topic_score_codex":0.0017882908,"about_ca_topic_score_gemma":0.004601045,"teacher_disagreement_score":0.15429728,"about_ca_system_score_codex":0.0012965476,"about_ca_system_score_gemma":0.0021657187,"threshold_uncertainty_score":0.5161758},"labels":[],"label_agreement":null},{"id":"W4406389131","doi":"10.2139/ssrn.5098874","title":"Myotubularin Related Protein 7, a Novel Stim1 Binding Protein","year":2025,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Computational biology; Computer science; Biology","score_opus":0.009890896831931001,"score_gpt":0.2526875925149031,"score_spread":0.24279669568297207,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406389131","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9531921,0.015853705,0.0117690815,0.0013064453,0.00055733,0.00006064348,0.002850493,0.0005274518,0.013882769],"genre_scores_gemma":[0.9457559,0.0050534266,0.0118115675,0.00064570905,0.00022364665,0.00006359672,0.010035481,0.00009730804,0.026313262],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992824,0.000008420668,0.0000037848292,0.000024735678,0.0000227667,0.000012012503],"domain_scores_gemma":[0.9999372,0.0000103026005,0.0000173417,0.000006362976,0.0000084730555,0.000020354979],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000079870944,0.0002918989,0.00041213422,0.0002902627,0.00035229936,0.00031246356,0.00031053205,0.0006995828,0.0037232754],"category_scores_gemma":[0.00013121434,0.00012191623,0.00031808022,0.00025708633,0.00018823144,0.00021783647,0.00033369494,0.0005345818,0.0019344111],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002642678,0.000021191048,0.00055165635,0.0001540141,0.000029351357,0.0011764714,0.000020817952,0.00013876075,0.98892933,0.0008963827,0.00087986747,0.006937783],"study_design_scores_gemma":[0.00009884274,0.00046395525,0.031897157,0.000040403134,0.00016888864,0.016561676,0.00013934543,0.006658391,0.87698877,0.0029249869,0.06400983,0.000047904192],"about_ca_topic_score_codex":0.00023770053,"about_ca_topic_score_gemma":0.00035896277,"teacher_disagreement_score":0.0037232754,"about_ca_system_score_codex":0.00036848124,"about_ca_system_score_gemma":0.00015291072,"threshold_uncertainty_score":0.012455583},"labels":[],"label_agreement":null},{"id":"W4406546841","doi":"10.1016/s1541-9800(07)70535-5","title":"10.1016/s1541-9800(07)70535-5","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Calcineurin; Term (time); Medicine; Internal medicine; Physics; Transplantation","score_opus":0.004894923163334725,"score_gpt":0.18270475220996119,"score_spread":0.17780982904662646,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406546841","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0004675707,0.0006725195,0.00074203644,0.0005745158,0.00044451398,0.00011240295,0.0007833043,0.0008511953,0.9953519],"genre_scores_gemma":[0.00049197616,0.00023917803,0.00034730343,0.00022884512,0.00008581242,0.000053815544,0.00042057375,0.00012154185,0.99801105],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993543,0.000039063936,0.00005145294,0.00023580574,0.00018117134,0.00013820802],"domain_scores_gemma":[0.9977563,0.000509892,0.00014725066,0.0002206217,0.0004743689,0.0008915886],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0010099323,0.0029876572,0.0018383197,0.0025079802,0.0024364765,0.0040467205,0.0032556388,0.0059675425,0.98734796],"category_scores_gemma":[0.0014384792,0.00088131137,0.0015330316,0.0022678075,0.0017583126,0.0047948505,0.0029245757,0.0032181877,0.99170727],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038141702,0.00022077627,0.0006388657,0.0006012853,0.00003981979,0.0002600423,0.00008682244,0.00037764045,0.0028515588,0.005061959,0.33675972,0.65272],"study_design_scores_gemma":[0.000054600132,0.00010851948,0.000673412,0.0002692944,0.000012932037,0.00032704018,0.00008956424,0.000154436,0.0005048266,0.000586953,0.9971957,0.000022643118],"about_ca_topic_score_codex":0.0029155891,"about_ca_topic_score_gemma":0.0025703828,"teacher_disagreement_score":0.0126520395,"about_ca_system_score_codex":0.0011555749,"about_ca_system_score_gemma":0.0012589799,"threshold_uncertainty_score":0.018046498},"labels":[],"label_agreement":null},{"id":"W4406811358","doi":"","title":"Le facteur de transcription MEF2 (Myocyte Enhancer Factor 2) : un nouveau régulateur de l'expression de Gsta1 dans les cellules de Leydig MA-10","year":2014,"lang":"fr","type":"article","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"Mef2; Transcription factor; Enhancer; Molecular biology; Biology; Genetics; Gene","score_opus":0.009179977475011685,"score_gpt":0.22530856726100132,"score_spread":0.21612858978598964,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406811358","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93607813,0.023542719,0.015471944,0.0017975207,0.000669435,0.000045909375,0.0010527222,0.00032498507,0.021016616],"genre_scores_gemma":[0.9472072,0.0050044954,0.002585552,0.0002420116,0.00024573976,0.000042657583,0.00080252293,0.00006162359,0.043808334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99988854,0.000019361123,0.000004523745,0.000037484155,0.000024177321,0.000025867854],"domain_scores_gemma":[0.9999236,0.000020394224,0.000011732769,0.000006338167,0.000016139884,0.000021924257],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022797503,0.00037323622,0.00026675774,0.00032285854,0.00047733216,0.00079650985,0.0001643062,0.00044303405,0.0037117924],"category_scores_gemma":[0.0001659886,0.00014647262,0.00035136324,0.00015791527,0.0003690587,0.00036988166,0.00029805335,0.0005834016,0.00085723394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017076316,0.00001700409,0.0022050617,0.000067230154,0.000013544901,0.00026180153,0.00008388196,0.00014605687,0.9887616,0.0014979991,0.00038761925,0.006387401],"study_design_scores_gemma":[0.000038151928,0.00023445002,0.072077714,0.000032563807,0.00004184942,0.0013775188,0.0005308165,0.0016279746,0.88524294,0.00061356445,0.038161036,0.000021387112],"about_ca_topic_score_codex":0.0017447361,"about_ca_topic_score_gemma":0.0018021599,"teacher_disagreement_score":0.0037117924,"about_ca_system_score_codex":0.0005347135,"about_ca_system_score_gemma":0.00023865703,"threshold_uncertainty_score":0.012417197},"labels":[],"label_agreement":null},{"id":"W4406927552","doi":"10.1128/msphere.01078-24","title":"Structural analysis of extracellular ATP-independent chaperones of streptococcal species and protein substrate interactions","year":2025,"lang":"en","type":"article","venue":"mSphere","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary; University of Toronto","funders":"Argonne National Laboratory; Office of Science; National Institute of General Medical Sciences; Michigan Technology Tri-Corridor; Directorate for Biological Sciences; U.S. Department of Health and Human Services; National Institutes of Health; National Institute of Allergy and Infectious Diseases; University of Pittsburgh; Northwestern University; U.S. Department of Energy","keywords":"Foldase; Pneumolysin; Virulence; Biology; Chaperone (clinical); Peptidylprolyl isomerase; Cyclophilin; Secretion; Microbiology; Streptococcus pneumoniae; Protein folding; Extracellular; Streptococcus pyogenes; Isomerase; Cell biology; Biochemistry; Bacteria; GroEL; Gene; Genetics","score_opus":0.012524439732267181,"score_gpt":0.2585577048721447,"score_spread":0.2460332651398775,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4406927552","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9984534,0.00033420222,0.00070627144,0.00003203164,0.0000070368733,0.000003609568,0.00009104459,0.000022417355,0.00034991224],"genre_scores_gemma":[0.99762577,0.00017998493,0.0013060685,0.000018057695,0.0000021362837,0.0000042625816,0.000476952,0.0000071982163,0.00037944308],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99994266,0.000010427005,0.000004416891,0.000008593871,0.000022050743,0.0000118548705],"domain_scores_gemma":[0.9999207,0.000009897362,0.000027261794,0.000006960849,0.000011938361,0.000023246797],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007051274,0.0002359677,0.00017165532,0.00014144358,0.00013416877,0.000182408,0.00023820168,0.00016218679,0.0006541774],"category_scores_gemma":[0.0001555816,0.00008609444,0.00021070037,0.00019671199,0.000088352615,0.00011859126,0.000119070915,0.0002382026,0.00016731561],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023010738,0.000055235887,0.0025263764,0.00009311767,0.000028291077,0.00032107296,0.000032121738,0.0011709948,0.992362,0.00038986118,0.0001505054,0.0026402697],"study_design_scores_gemma":[0.00004897022,0.00040577323,0.03614636,0.000028364393,0.00007777505,0.0010615565,0.00015246216,0.036709238,0.91930985,0.0003468636,0.005688519,0.000024179444],"about_ca_topic_score_codex":0.00089608127,"about_ca_topic_score_gemma":0.0012060686,"teacher_disagreement_score":0.00089608127,"about_ca_system_score_codex":0.00039595828,"about_ca_system_score_gemma":0.00020040825,"threshold_uncertainty_score":0.0028728843},"labels":[],"label_agreement":null},{"id":"W4407096894","doi":"10.5194/egusphere-2024-3353-ac3","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"École de Technologie Supérieure; Université du Québec à Montréal","funders":"","keywords":"Chemistry","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407096894","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00031906393,0.0015819616,0.00039415766,0.737907,0.21256107,0.00016835117,0.0010506938,0.0005795179,0.045438208],"genre_scores_gemma":[0.0044377204,0.0015005408,0.0004013576,0.68744373,0.074215844,0.00024201696,0.0006774916,0.00045710974,0.23062418],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974815,0.00042080242,0.00027329777,0.00036545272,0.001072283,0.0003866416],"domain_scores_gemma":[0.98797506,0.003504949,0.00039146608,0.00048650234,0.005922512,0.0017194827],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0027108905,0.0006861528,0.00086549966,0.0012247108,0.0025395597,0.0034618885,0.0023205183,0.016431345,0.21050484],"category_scores_gemma":[0.035352465,0.00039097003,0.00091803004,0.0008707938,0.001444868,0.0029850209,0.0020223344,0.012786485,0.12380642],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00000984924,0.0000025215318,0.000034262637,0.0000133948515,8.834643e-7,0.000047302605,0.0000065147824,0.000003924185,0.000016368245,0.00023192297,0.99746084,0.002172229],"study_design_scores_gemma":[0.0000101427295,0.0000072595712,0.00022606015,0.000056553425,0.000002201111,0.00007847002,0.000046094963,0.00003603084,0.000069187765,0.00044048685,0.9990175,0.000010018656],"about_ca_topic_score_codex":0.0072150766,"about_ca_topic_score_gemma":0.010247465,"teacher_disagreement_score":0.78949517,"about_ca_system_score_codex":0.0032219207,"about_ca_system_score_gemma":0.0032848169,"threshold_uncertainty_score":0.70420885},"labels":[],"label_agreement":null},{"id":"W4407366103","doi":"10.5194/egusphere-2024-3828-ac1","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Saint Mary's University","funders":"","keywords":"Chemistry","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407366103","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00026233637,0.0017731077,0.00033345647,0.6165747,0.2992795,0.00020090869,0.0021434806,0.0007979757,0.0786345],"genre_scores_gemma":[0.0025099511,0.0012535527,0.00027704603,0.65016824,0.0861857,0.0002507775,0.00083270896,0.00041868258,0.25810334],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979461,0.00031854757,0.00021848004,0.00037024263,0.00075330306,0.00039329898],"domain_scores_gemma":[0.993134,0.0019724972,0.00025221342,0.00043414035,0.0031593952,0.0010477122],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0023936876,0.000845703,0.0009976294,0.0011964616,0.0027783979,0.0041712923,0.0025194508,0.018744571,0.30036977],"category_scores_gemma":[0.024923313,0.0005064401,0.0013774395,0.0009182054,0.0016355343,0.0032185838,0.002656116,0.014157012,0.20435111],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007907197,0.0000024525202,0.000025009958,0.000012698882,7.5217184e-7,0.00002750311,0.0000056146673,0.0000030530464,0.000013795211,0.0002473609,0.99758613,0.0020677708],"study_design_scores_gemma":[0.000011253199,0.0000065759436,0.00018170994,0.000058602815,0.0000018427579,0.000040666255,0.00003919498,0.000018107776,0.000043686978,0.00040351518,0.9991872,0.0000075464063],"about_ca_topic_score_codex":0.007913758,"about_ca_topic_score_gemma":0.009415307,"teacher_disagreement_score":0.30036977,"about_ca_system_score_codex":0.0031544997,"about_ca_system_score_gemma":0.0033184844,"threshold_uncertainty_score":0.9979376},"labels":[],"label_agreement":null},{"id":"W4407678948","doi":"10.1002/rmv.70023","title":"Nuclear Factor of Activated T Cells Signalling and Viral Pathogens: A Dynamic Cross‐Talk","year":2025,"lang":"en","type":"review","venue":"Reviews in Medical Virology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"NFAT; Transcription factor; Cell biology; Biology; Calcineurin; Hedgehog signaling pathway; Signal transduction; Genetics; Transplantation; Medicine","score_opus":0.02121011141876376,"score_gpt":0.34279354427648134,"score_spread":0.32158343285771757,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407678948","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00015071369,0.9981748,0.0001276988,0.00023343526,0.0002891351,0.000003388365,0.000011546767,0.0000065815716,0.0010028143],"genre_scores_gemma":[0.00067733356,0.9979917,0.00012513572,0.00017618125,0.00018297968,0.0000051535135,0.000022491125,0.0000011690569,0.00081789226],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.99986196,0.000022281376,0.000014821561,0.00002364047,0.000058385525,0.00001895009],"domain_scores_gemma":[0.99988925,0.000049027913,0.000014854967,0.0000033141803,0.000029445588,0.000014023563],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00033826276,0.0007714498,0.00096761447,0.0011846726,0.00023373678,0.0010208518,0.00060992985,0.0009909199,0.0031881717],"category_scores_gemma":[0.0002568095,0.00022384794,0.0003859201,0.0013321774,0.00037865434,0.0010359086,0.00058374036,0.0015658739,0.0020433783],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001247551,0.000067764995,0.00014289403,0.015282667,0.00010962629,0.00035224025,0.00009181939,0.000391188,0.008507226,0.0063776975,0.028510194,0.94004196],"study_design_scores_gemma":[0.00001542505,0.000091247006,0.0004923339,0.0015680867,0.000060329057,0.0011959658,0.00005167156,0.000060976607,0.0010567475,0.001959602,0.99343336,0.0000143260595],"about_ca_topic_score_codex":0.0004998365,"about_ca_topic_score_gemma":0.00083581347,"teacher_disagreement_score":0.0031881717,"about_ca_system_score_codex":0.00060431386,"about_ca_system_score_gemma":0.0008003889,"threshold_uncertainty_score":0.010665476},"labels":[],"label_agreement":null},{"id":"W4407931410","doi":"10.1101/2025.02.23.639749","title":"Astrocytic activation of EMMPRIN contributes to their pathological phenotype in ALS","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université Laval","funders":"","keywords":"Pathological; Phenotype; Neuroscience; Medicine; Psychology; Chemistry; Pathology; Gene; Biochemistry","score_opus":0.014564465652842131,"score_gpt":0.23952145869127175,"score_spread":0.22495699303842961,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4407931410","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99611807,0.0015668923,0.0011309448,0.000042643453,0.000030018384,0.000018930354,0.00010362907,0.000038170554,0.00095070584],"genre_scores_gemma":[0.9966905,0.00082152145,0.0005634161,0.000027008635,0.000023358401,0.00002129025,0.0001247412,0.0000057087677,0.0017223302],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99991846,0.000015954034,0.000010832433,0.00001093834,0.000025295833,0.00001856109],"domain_scores_gemma":[0.99992216,0.0000038105493,0.000023176437,0.0000046556133,0.00002122502,0.00002504102],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009462056,0.00031434087,0.00018654263,0.0002639596,0.00019762284,0.00020015024,0.00007371608,0.00027127226,0.00082038145],"category_scores_gemma":[0.000064647604,0.00008855674,0.00015632153,0.00014218462,0.00014510224,0.00013224207,0.000248303,0.00033301863,0.00036339395],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005110327,0.0000634795,0.0034163923,0.000096787386,0.000013519909,0.001428346,0.0000446905,0.00003993691,0.99239254,0.000072999894,0.0000862485,0.0018340596],"study_design_scores_gemma":[0.00005943216,0.0013324023,0.23074596,0.000049686798,0.00015344875,0.012317673,0.0003728154,0.0018067367,0.74430066,0.000562514,0.008285515,0.000013200731],"about_ca_topic_score_codex":0.00020442951,"about_ca_topic_score_gemma":0.00029242897,"teacher_disagreement_score":0.00082038145,"about_ca_system_score_codex":0.000117294556,"about_ca_system_score_gemma":0.0000671432,"threshold_uncertainty_score":0.0027443767},"labels":[],"label_agreement":null},{"id":"W4408470136","doi":"10.5194/egusphere-2024-2958-ac2","title":"Additional information on RC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Environment and Climate Change Canada","funders":"","keywords":"Computer science","score_opus":0.012629173488299271,"score_gpt":0.2815257665288646,"score_spread":0.2688965930405653,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4408470136","genre_codex":"dataset","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00039267715,0.0003650337,0.0031790808,0.00096465636,0.001864079,0.00046749564,0.65148014,0.01654186,0.3247449],"genre_scores_gemma":[0.009837001,0.001035902,0.0068673627,0.0018636599,0.0006963726,0.0010065323,0.5859817,0.026703931,0.36600754],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9986243,0.00015158116,0.0000876995,0.00031991678,0.00059967354,0.00021686843],"domain_scores_gemma":[0.9966066,0.000521821,0.00011445386,0.0007972597,0.0014412393,0.00051872],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0014271948,0.0015293319,0.0021329639,0.003639255,0.0022102955,0.0057918164,0.0039303806,0.0021271512,0.9325883],"category_scores_gemma":[0.0081624035,0.00094842335,0.0011934118,0.007171186,0.0005352918,0.0033822784,0.0027660276,0.0017870672,0.8328342],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000035092424,0.00001030268,0.00010833924,0.00022993915,0.0000044417725,0.000016764992,0.000016885593,0.00012985132,0.00015102071,0.00093364075,0.9871611,0.0112026],"study_design_scores_gemma":[0.000032022224,0.000008759542,0.00045676593,0.00007892818,0.0000061271703,0.000017623253,0.000032584743,0.00019047767,0.00031575907,0.0008349494,0.9980123,0.000013627145],"about_ca_topic_score_codex":0.022115037,"about_ca_topic_score_gemma":0.020066809,"teacher_disagreement_score":0.06741172,"about_ca_system_score_codex":0.0022216802,"about_ca_system_score_gemma":0.004047045,"threshold_uncertainty_score":0.09615463},"labels":[],"label_agreement":null},{"id":"W4409117068","doi":"10.1038/s41423-025-01277-8","title":"Comment on: Glycogen synthase kinase 3 controls T-cell exhaustion by regulating NFAT activation","year":2025,"lang":"en","type":"letter","venue":"Cellular and Molecular Immunology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont","funders":"Canadian HIV Trials Network, Canadian Institutes of Health Research","keywords":"GSK-3; NFAT; Glycogen synthase; ATP synthase; Cell biology; Kinase; Chemistry; Biology; Enzyme; Biochemistry; Phosphorylation; Gene; Transcription factor","score_opus":0.006684062121823879,"score_gpt":0.21635000019857742,"score_spread":0.20966593807675354,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409117068","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00056837883,0.0014691325,0.00015892807,0.93081903,0.0650691,0.000021602955,0.00010769365,0.00004793273,0.0017382135],"genre_scores_gemma":[0.0039152307,0.0007297981,0.00016479295,0.9221974,0.06781189,0.000055781627,0.0000380455,0.00002152654,0.0050655133],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9975756,0.00049613096,0.0002729755,0.00046430624,0.0006962575,0.00049483834],"domain_scores_gemma":[0.9946262,0.0031536105,0.0004293018,0.00019879595,0.0008129119,0.00077917316],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0034085049,0.0013227434,0.0019249631,0.0009599573,0.003936961,0.0033872777,0.0023099445,0.06457607,0.0066120788],"category_scores_gemma":[0.016359055,0.0009434736,0.0021692046,0.0006240303,0.0034050453,0.0025225924,0.0017249862,0.04468604,0.0065214923],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00022279227,0.000042208987,0.0004717475,0.00005774382,0.000032927706,0.0020383107,0.000087074644,0.00008118556,0.00038869563,0.0017450999,0.9900332,0.004798958],"study_design_scores_gemma":[0.0006840588,0.00031387247,0.0038024343,0.00036453485,0.00020717748,0.0026094066,0.0004097362,0.0013718052,0.0014316393,0.016075445,0.9725275,0.00020247475],"about_ca_topic_score_codex":0.005272063,"about_ca_topic_score_gemma":0.0064392826,"teacher_disagreement_score":0.06457607,"about_ca_system_score_codex":0.00570244,"about_ca_system_score_gemma":0.003073448,"threshold_uncertainty_score":0.041374266},"labels":[],"label_agreement":null},{"id":"W4409758575","doi":"10.5194/egusphere-2024-4086-ac3","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Environment and Climate Change Canada","funders":"","keywords":"Political science","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409758575","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00029214297,0.0017531504,0.00049977127,0.5126705,0.2996474,0.00038232718,0.0031467634,0.0011110381,0.18049696],"genre_scores_gemma":[0.0020553654,0.00085416075,0.00034233226,0.49821362,0.059841644,0.0004347962,0.0010346991,0.0005123696,0.43671095],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9972011,0.00034295573,0.0002622338,0.00049634074,0.00114647,0.00055099215],"domain_scores_gemma":[0.9932069,0.001806702,0.00022315184,0.00054770394,0.0032365595,0.0009789254],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.003044241,0.001074856,0.0011509751,0.0012756026,0.0033257883,0.0057802657,0.0030852654,0.025663916,0.3606195],"category_scores_gemma":[0.021132886,0.0006288113,0.001766036,0.0012546739,0.0019864058,0.003759294,0.0029633401,0.016407002,0.28403634],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008574602,0.0000034772825,0.000020610345,0.0000152145885,8.560186e-7,0.000018687335,0.000005416843,0.0000047638723,0.000022140686,0.0005558447,0.99702543,0.002318981],"study_design_scores_gemma":[0.000010591519,0.0000057956813,0.00017180711,0.000045817167,0.0000013731164,0.000015711474,0.000025686548,0.000019259098,0.00004202095,0.0005011028,0.9991534,0.0000074520644],"about_ca_topic_score_codex":0.009388692,"about_ca_topic_score_gemma":0.010393807,"teacher_disagreement_score":0.3606195,"about_ca_system_score_codex":0.003888499,"about_ca_system_score_gemma":0.0040381295,"threshold_uncertainty_score":0.9119987},"labels":[],"label_agreement":null},{"id":"W4409889295","doi":"10.1021/acs.jmedchem.5c00220","title":"Broad Target Screening Reveals Abundance of FKBP12-Based Molecular Glues in Focused Libraries","year":2025,"lang":"en","type":"article","venue":"Journal of Medicinal Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Structural Genomics Consortium","funders":"Structural Genomics Consortium; Bundesministerium für Bildung und Forschung; Deutsche Forschungsgemeinschaft","keywords":"FKBP; Drug discovery; Chemistry; Computational biology; Drug repositioning; Drug; Biochemistry; Pharmacology; Biology","score_opus":0.007855922478821418,"score_gpt":0.26019155781169107,"score_spread":0.2523356353328696,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409889295","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98067755,0.0015953518,0.014026699,0.000097171775,0.00001609374,0.00014050126,0.0005875485,0.00036810455,0.0024908625],"genre_scores_gemma":[0.98590904,0.001025583,0.00915405,0.00013644523,0.0000064937194,0.000088759596,0.0010467662,0.000047412635,0.0025854288],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997298,0.00003545098,0.000017704833,0.00006675964,0.00009286921,0.00005731555],"domain_scores_gemma":[0.99986815,0.000029333558,0.00002541059,0.000015925778,0.000021744429,0.00003943672],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00028496806,0.0005599841,0.0005305429,0.0006275471,0.00021612305,0.00033274572,0.00029840876,0.00032391943,0.0016452482],"category_scores_gemma":[0.000294687,0.0001760327,0.00030154065,0.00047432183,0.0002456218,0.00025784757,0.00048236438,0.00045512998,0.0006557679],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011974108,0.00005521603,0.0003162879,0.000056148336,0.000021259963,0.00008699452,0.000020405165,0.00042260432,0.9935315,0.0000920287,0.000092083654,0.005185691],"study_design_scores_gemma":[0.000028536724,0.0012614563,0.0031313915,0.000012884018,0.000053083895,0.00031466933,0.00003417898,0.0012248091,0.99180603,0.00006556506,0.0020560212,0.000011360363],"about_ca_topic_score_codex":0.00028125106,"about_ca_topic_score_gemma":0.00084712857,"teacher_disagreement_score":0.0016452482,"about_ca_system_score_codex":0.00030195693,"about_ca_system_score_gemma":0.00018382138,"threshold_uncertainty_score":0.005503893},"labels":[],"label_agreement":null},{"id":"W4409994378","doi":"10.1016/j.cstres.2025.100079","title":"HDAC1 is involved in the destabilization of the HSF2 protein under nonstress and stress conditions","year":2025,"lang":"en","type":"article","venue":"Cell Stress and Chaperones","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; Syöpäsäätiö; Centre National de la Recherche Scientifique; Magnus Ehrnroothin Säätiö; Labex; Institut National de la Santé et de la Recherche Médicale; Institut Pasteur; Sigrid Juséliuksen Säätiö; Fondation pour la Recherche Médicale; Academy of Finland; Agence Nationale de la Recherche; Infrastructures en Biologie Santé et Agronomie; Fondation Jérôme Lejeune","keywords":"Stress (linguistics); Unfolded protein response; Cell biology; Biology; Philosophy; Linguistics","score_opus":0.008906697382460626,"score_gpt":0.23530754662090358,"score_spread":0.22640084923844295,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4409994378","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92447543,0.047543578,0.010772246,0.00061287597,0.000633981,0.00010868181,0.0045374376,0.00084745674,0.010468302],"genre_scores_gemma":[0.9805669,0.004266659,0.0015755956,0.00012463682,0.00006693628,0.000040896764,0.0035210177,0.0000598644,0.009777342],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.999845,0.000011791207,0.000008918415,0.000055208566,0.000036680332,0.000042294043],"domain_scores_gemma":[0.9999368,0.000002926888,0.000018874363,0.000005511712,0.000012992515,0.000022905644],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00011355369,0.00065750175,0.00038774734,0.0003018533,0.0004396413,0.00032742132,0.00036560884,0.00032621055,0.0037606177],"category_scores_gemma":[0.00012315302,0.00018391499,0.00057159975,0.00020526274,0.0002592655,0.00018363008,0.0002678973,0.0003500823,0.0012890575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005236341,0.00005823063,0.004068161,0.00029834322,0.000063197425,0.00040833047,0.000042050087,0.000101291385,0.98174906,0.000339081,0.0014349908,0.010913659],"study_design_scores_gemma":[0.00008261913,0.00023559244,0.1424929,0.00003105311,0.00010221793,0.0017415944,0.00009301476,0.0015811371,0.82386255,0.00027706663,0.02947468,0.000025576326],"about_ca_topic_score_codex":0.0025981907,"about_ca_topic_score_gemma":0.0028484396,"teacher_disagreement_score":0.0037606177,"about_ca_system_score_codex":0.0005428109,"about_ca_system_score_gemma":0.0002984432,"threshold_uncertainty_score":0.012580454},"labels":[],"label_agreement":null},{"id":"W4410595775","doi":"10.1016/j.semcancer.2025.05.011","title":"The central role of Pin1 in age-related cancer signaling pathways","year":2025,"lang":"en","type":"review","venue":"Seminars in Cancer Biology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Canada Foundation for Innovation; Ontario Institute for Cancer Research","keywords":"PIN1; Prolyl isomerase; Phosphorylation; Isomerase; Signal transduction; Peptidylprolyl isomerase; Regulator; Expansive; Biology; Cancer; Cancer research; Cell biology; Chemistry; Biochemistry; Enzyme; Genetics; Gene; Materials science","score_opus":0.021010572567268893,"score_gpt":0.3376802243330037,"score_spread":0.3166696517657348,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4410595775","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00027000628,0.9972977,0.00016578034,0.00041221603,0.00024905714,0.000004230294,0.000023952904,0.000011002432,0.0015659877],"genre_scores_gemma":[0.0013617099,0.9969703,0.00016573192,0.00025183504,0.00017915144,0.000006234047,0.000038602,0.0000016362638,0.0010247919],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999206,0.00001186995,0.0000084078765,0.000016814158,0.000027482369,0.000014751457],"domain_scores_gemma":[0.9999206,0.00002779275,0.00001161384,0.000002537832,0.000023357305,0.000014171396],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00032172597,0.00059731316,0.0006617536,0.000950571,0.00022432889,0.00076469086,0.0005645509,0.0007391752,0.0030811615],"category_scores_gemma":[0.0002849447,0.00018965953,0.00027743093,0.00074730907,0.00035748983,0.0010670049,0.0005881187,0.0016760103,0.0019298814],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015060559,0.00005276634,0.0001439106,0.010143542,0.00005553812,0.00042086391,0.000065991466,0.0004894461,0.0062488522,0.0092728315,0.033263974,0.9396918],"study_design_scores_gemma":[0.000016632706,0.000080505444,0.00051761756,0.0010326487,0.000039559283,0.0012260915,0.000032897005,0.000082201936,0.0011257313,0.0023298315,0.9935033,0.000012953316],"about_ca_topic_score_codex":0.0004734588,"about_ca_topic_score_gemma":0.00073692977,"teacher_disagreement_score":0.0030811615,"about_ca_system_score_codex":0.0005584584,"about_ca_system_score_gemma":0.0006533235,"threshold_uncertainty_score":0.01030755},"labels":[],"label_agreement":null},{"id":"W4411133068","doi":"10.5194/egusphere-2024-3976-ac2","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Environment and Climate Change Canada; China Meteorological Administration; National Oceanic and Atmospheric Administration; Commonwealth Scientific and Industrial Research Organisation","keywords":"Chemistry","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411133068","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00025874228,0.0016372429,0.00034847978,0.6054892,0.32287356,0.00020308606,0.00171109,0.00089610205,0.0665826],"genre_scores_gemma":[0.0027302168,0.0011448332,0.00031638163,0.65601087,0.09240413,0.00026210042,0.0007688638,0.0004810055,0.24588151],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9977398,0.00035958466,0.00023080234,0.00040633534,0.0008179073,0.00044555022],"domain_scores_gemma":[0.9928462,0.0019618394,0.0002538084,0.0004428164,0.0032229503,0.0012724182],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0024660889,0.00095366663,0.001072151,0.0012716043,0.0030186924,0.0045079715,0.0027313319,0.020890681,0.30762425],"category_scores_gemma":[0.025802286,0.0005544627,0.0014622833,0.0009307265,0.0017833309,0.0034923241,0.002792521,0.016399203,0.20403586],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009295731,0.0000027833285,0.000024313194,0.000012616057,9.0808146e-7,0.000032023217,0.000005353,0.0000032555738,0.0000143820025,0.00022367424,0.9976666,0.0020047936],"study_design_scores_gemma":[0.000013761411,0.000008095689,0.00017210896,0.00005894221,0.0000022136837,0.00004889926,0.00004200567,0.000023438972,0.000054738513,0.00047703207,0.9990902,0.000008512007],"about_ca_topic_score_codex":0.0069505027,"about_ca_topic_score_gemma":0.0083604185,"teacher_disagreement_score":0.6923758,"about_ca_system_score_codex":0.0032743877,"about_ca_system_score_gemma":0.0033984757,"threshold_uncertainty_score":0.98758996},"labels":[],"label_agreement":null},{"id":"W4411483432","doi":"10.5194/egusphere-2025-1940-cc2","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Environment and Climate Change Canada","funders":"","keywords":"Computer science","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411483432","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00024211156,0.001144902,0.00029826077,0.72682405,0.23417155,0.00015677777,0.0012197685,0.00054063904,0.035401937],"genre_scores_gemma":[0.0030929446,0.0012211812,0.00032782595,0.7148564,0.09269688,0.00026050574,0.0007710529,0.0004019876,0.18637128],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99747866,0.0004055203,0.00030969843,0.0003500569,0.0010467526,0.00040922363],"domain_scores_gemma":[0.987912,0.0037382846,0.00041540115,0.0005318169,0.005646797,0.0017557257],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0029757724,0.0007480198,0.00093104324,0.0013509357,0.0026685111,0.0032837086,0.0022377605,0.018540582,0.18652841],"category_scores_gemma":[0.034642782,0.0004579629,0.000982532,0.001034152,0.0016330649,0.0028625382,0.0021978584,0.013114185,0.11900871],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009210478,0.000002004351,0.000032592096,0.000013603224,7.455633e-7,0.000037390553,0.0000056483495,0.0000034780358,0.000015167955,0.0001848318,0.9980882,0.0016071558],"study_design_scores_gemma":[0.000012703094,0.0000064021233,0.00028419442,0.00006007523,0.0000021826752,0.0000568993,0.000043075157,0.000029256698,0.00005939555,0.00043852648,0.99899596,0.000011347229],"about_ca_topic_score_codex":0.008956102,"about_ca_topic_score_gemma":0.011909728,"teacher_disagreement_score":0.81347156,"about_ca_system_score_codex":0.003431968,"about_ca_system_score_gemma":0.0033390087,"threshold_uncertainty_score":0.6239997},"labels":[],"label_agreement":null},{"id":"W4411543105","doi":"10.1186/s41232-025-00384-3","title":"Ca2+ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells","year":2025,"lang":"en","type":"review","venue":"Inflammation and Regeneration","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"Mochida Memorial Foundation for Medical and Pharmaceutical Research; Hori Sciences and Arts Foundation; Nakatomi Foundation; Takeda Science Foundation; Japan Foundation for Applied Enzymology; Suzuken Memorial Foundation","keywords":"Lipid microdomain; Myocyte; Excitation–contraction coupling; Coupling (piping); Vascular smooth muscle; Cardiac muscle; Cell biology; Internal medicine; Cardiology; Chemistry; Biology; Medicine; Smooth muscle; Materials science; Biochemistry","score_opus":0.013586139931779132,"score_gpt":0.2593297718033068,"score_spread":0.24574363187152767,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411543105","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.009800952,0.98050207,0.0028544846,0.0007790179,0.0007362507,0.000027788461,0.0001464991,0.00006145791,0.0050914483],"genre_scores_gemma":[0.058810174,0.9304266,0.0020616266,0.0007990059,0.0008697736,0.000064605054,0.00033601365,0.000012331197,0.0066199726],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9998871,0.00001564771,0.000015576867,0.00002811529,0.000027757067,0.000025727853],"domain_scores_gemma":[0.9999217,0.000021158961,0.000017874185,0.0000030890085,0.000024326819,0.000011907684],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020538432,0.00044079003,0.0006619529,0.0005735111,0.00029629137,0.0006983578,0.0004090074,0.0007282731,0.0017981551],"category_scores_gemma":[0.00015689422,0.00019868484,0.00044593433,0.0005888209,0.0002493792,0.0006070111,0.0003888393,0.00071267417,0.00072613556],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003893547,0.00013512385,0.0015454257,0.02487715,0.00017119269,0.002564178,0.0006907993,0.0017591626,0.43051603,0.018725721,0.01604638,0.5025795],"study_design_scores_gemma":[0.000044042987,0.00087475113,0.012778637,0.0019549234,0.0002912459,0.004728637,0.00051288307,0.0016548347,0.08388005,0.009579071,0.88359815,0.00010278273],"about_ca_topic_score_codex":0.0005647094,"about_ca_topic_score_gemma":0.0005580436,"teacher_disagreement_score":0.0017981551,"about_ca_system_score_codex":0.00041729785,"about_ca_system_score_gemma":0.00038320263,"threshold_uncertainty_score":0.00601542},"labels":[],"label_agreement":null},{"id":"W4411569222","doi":"10.1002/pmic.13980","title":"Covalent Inhibition of the Peptidyl‐Prolyl Isomerase Pin1 by Sulfopin Results in a Broad Impact on the Phosphoproteome of Human Osteosarcoma U2‐OS Cells","year":2025,"lang":"en","type":"article","venue":"PROTEOMICS","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Canada Foundation for Innovation; Ontario Institute for Cancer Research","keywords":"PIN1; Osteosarcoma; Isomerase; Chemistry; Biochemistry; Covalent bond; Posttranslational modification; Computational biology; Prolyl isomerase; Biology; Enzyme; Cancer research; Organic chemistry","score_opus":0.008089386624383823,"score_gpt":0.2582599983734384,"score_spread":0.2501706117490546,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411569222","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9946242,0.0023063328,0.0011759391,0.00007301238,0.00002848488,0.000017076469,0.0007803823,0.000054037897,0.0009404566],"genre_scores_gemma":[0.99360645,0.001616413,0.001230592,0.00007184153,0.000008298918,0.0000277677,0.0012831528,0.000015879561,0.002139506],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998969,0.000008357887,0.000007883743,0.000023834078,0.000039448874,0.000023649773],"domain_scores_gemma":[0.99995923,0.0000054545553,0.000016625692,0.000003826996,0.0000049025616,0.000010062474],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008470395,0.0003885838,0.00023346729,0.00019426538,0.00013768022,0.00022621965,0.00011485931,0.00016379876,0.0008696814],"category_scores_gemma":[0.00006223367,0.00012468142,0.00021828806,0.00018702884,0.00016754007,0.00012603647,0.00017572363,0.00030538038,0.00018052493],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010238617,0.000009859043,0.00017396505,0.000024842619,0.0000051670577,0.00002438464,0.000008149353,0.000031244876,0.99890697,0.00001531007,0.000021015945,0.00067675684],"study_design_scores_gemma":[0.0000050826425,0.00019465532,0.00925845,0.0000030986362,0.000012899711,0.00010909213,0.00003390159,0.00036255192,0.9887183,0.000014642067,0.0012841618,0.0000031834527],"about_ca_topic_score_codex":0.00076937064,"about_ca_topic_score_gemma":0.0012245248,"teacher_disagreement_score":0.0008696814,"about_ca_system_score_codex":0.00015136028,"about_ca_system_score_gemma":0.00015383586,"threshold_uncertainty_score":0.002909422},"labels":[],"label_agreement":null},{"id":"W4411659005","doi":"10.5194/egusphere-2025-2083-ac1","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Materials science","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411659005","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0003752205,0.0020585808,0.00039370617,0.717941,0.20571098,0.00019284042,0.0011911985,0.00066134386,0.07147521],"genre_scores_gemma":[0.0044639134,0.0012710098,0.00031361054,0.67912954,0.057043113,0.00024984524,0.0005170416,0.00038471774,0.2566272],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.997938,0.00037473487,0.00020369893,0.00036059957,0.00078120787,0.00034181046],"domain_scores_gemma":[0.9935747,0.0019863816,0.00024279827,0.00034039794,0.002911338,0.0009444355],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0019659474,0.000866904,0.0009861384,0.0011492178,0.0028975853,0.0036698908,0.0025025357,0.019353164,0.2615295],"category_scores_gemma":[0.02607098,0.00045890242,0.0011518038,0.00086395314,0.00169864,0.0032138405,0.0025375662,0.015950864,0.14339498],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000010819274,0.0000026770695,0.000038168164,0.000013870405,0.0000010342443,0.000052893447,0.000009700471,0.0000040203445,0.000016941574,0.00029235185,0.99714583,0.0024116503],"study_design_scores_gemma":[0.000009554033,0.000007726982,0.0001868869,0.000059864662,0.0000020880416,0.00008929844,0.00007223192,0.000030909196,0.00006740574,0.00048326445,0.9989819,0.000008861124],"about_ca_topic_score_codex":0.006463869,"about_ca_topic_score_gemma":0.008115081,"teacher_disagreement_score":0.2615295,"about_ca_system_score_codex":0.00312021,"about_ca_system_score_gemma":0.002819513,"threshold_uncertainty_score":0.8749033},"labels":[],"label_agreement":null},{"id":"W4411974527","doi":"10.1101/2025.07.01.662614","title":"A stress-dependent postembryonic role for the core CPA factor CFIM-1 in germline integrity","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Hospital for Sick Children; Queen's University; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Germline; Core (optical fiber); Stress (linguistics); Factor (programming language); Business; Psychology; Biology; Genetics; Computer science; Telecommunications","score_opus":0.02154831731449788,"score_gpt":0.26236480752300007,"score_spread":0.24081649020850218,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411974527","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99153847,0.001866507,0.0038410968,0.00015137403,0.000035837817,0.000014597598,0.0010234986,0.0001545968,0.0013740412],"genre_scores_gemma":[0.9931593,0.00045961194,0.0023114302,0.000068265916,0.000012174702,0.000014214541,0.0009319631,0.000029380497,0.0030136425],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99992037,0.0000041303883,0.0000035314663,0.000029292514,0.000021410453,0.000021144793],"domain_scores_gemma":[0.9999052,0.0000109473995,0.000036349207,0.000009787391,0.000010461666,0.000027236165],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007817899,0.00035896857,0.00018248108,0.00019778796,0.00022741646,0.00026787122,0.00010376304,0.00029061074,0.0009306817],"category_scores_gemma":[0.00008603461,0.000097752025,0.00015964576,0.00008245603,0.0002800972,0.00019549453,0.00024826016,0.00047337124,0.00028171588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000020826763,0.000002869619,0.00031148473,0.000013426394,0.0000010015779,0.0000336053,0.000004233914,0.00001689594,0.9989672,0.000048815615,0.000033306755,0.0005463326],"study_design_scores_gemma":[0.0000037255254,0.00008659287,0.046714943,0.000010208762,0.00000708464,0.0003647177,0.00004124373,0.00079789443,0.9498566,0.00013705039,0.001974129,0.0000057787097],"about_ca_topic_score_codex":0.00047456307,"about_ca_topic_score_gemma":0.0007599486,"teacher_disagreement_score":0.0009306817,"about_ca_system_score_codex":0.00026641006,"about_ca_system_score_gemma":0.00018691743,"threshold_uncertainty_score":0.003113389},"labels":[],"label_agreement":null},{"id":"W4412389942","doi":"10.3390/ijms26146699","title":"A Novel Chemotherapy Combination to Enhance Proteotoxic Cell Death in Hepatocellular Carcinoma Experimental Models Without Killing Non-Cancer Cells","year":2025,"lang":"en","type":"article","venue":"International Journal of Molecular Sciences","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NAEJA-RGM Pharmaceuticals (Canada)","funders":"State of Florida; National Institutes of Health; U.S. Department of Veterans Affairs","keywords":"Ixazomib; Cancer research; Cancer cell; Proteasome inhibitor; Programmed cell death; Biology; Cancer; Hepatocellular carcinoma; Apoptosis; Proteasome; Cell biology; Carfilzomib; Biochemistry","score_opus":0.015905010530558,"score_gpt":0.313582414941916,"score_spread":0.29767740441135804,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412389942","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9856705,0.0058718165,0.0044724047,0.00024783198,0.00014650004,0.0003407781,0.00042070527,0.0002362983,0.0025931585],"genre_scores_gemma":[0.9881131,0.0034874592,0.004313951,0.00008093405,0.000030891635,0.00020791004,0.0006034628,0.000015989195,0.003146375],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999254,0.000012079858,0.000007814963,0.000017321543,0.000019915482,0.000017446431],"domain_scores_gemma":[0.99996614,0.0000041268486,0.000008487875,0.000004893422,0.0000049970217,0.000011417415],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000096977055,0.000358458,0.0004231413,0.00038763462,0.00011928741,0.00016743611,0.00019189328,0.00018650404,0.0014046725],"category_scores_gemma":[0.0000527856,0.000098859484,0.00022574779,0.00026997522,0.00015623972,0.00018374498,0.00012704267,0.0004478624,0.00018740461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001743023,0.000788309,0.0005642184,0.00031245867,0.000054841003,0.00013647653,0.00003337428,0.0005089768,0.9721539,0.00031893453,0.00048174922,0.022903746],"study_design_scores_gemma":[0.0008034576,0.011853419,0.0058690067,0.00002042599,0.00015313023,0.00085821754,0.000029958048,0.0013265176,0.96472734,0.00007998524,0.014258479,0.000020113803],"about_ca_topic_score_codex":0.0006981013,"about_ca_topic_score_gemma":0.0022622095,"teacher_disagreement_score":0.0014046725,"about_ca_system_score_codex":0.0002730841,"about_ca_system_score_gemma":0.00033236243,"threshold_uncertainty_score":0.004699111},"labels":[],"label_agreement":null},{"id":"W4412433496","doi":"10.5194/egusphere-2024-3286-ac1","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Chemistry","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412433496","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00036527062,0.0017956237,0.00044183378,0.5207478,0.343194,0.0003378694,0.0023094676,0.0011725448,0.12963563],"genre_scores_gemma":[0.0033534996,0.0011994945,0.00033697826,0.46390563,0.09111681,0.00031988515,0.0009825701,0.0005301725,0.43825498],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9983463,0.00026752212,0.00017356672,0.00026673413,0.000633079,0.00031284857],"domain_scores_gemma":[0.99493706,0.0013898197,0.00018146374,0.00033619365,0.0022288526,0.00092662155],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0018219192,0.00079880306,0.0008496613,0.0010982681,0.002289733,0.0033028699,0.0023465524,0.015476378,0.39320973],"category_scores_gemma":[0.019054523,0.00045458516,0.0011932862,0.0007211218,0.0013242572,0.0027101224,0.0024220035,0.011969165,0.25811166],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000104844885,0.0000034210334,0.000026853908,0.000012509683,7.950694e-7,0.000036928883,0.000004731298,0.0000035822934,0.000016375345,0.00020794488,0.997139,0.0025373683],"study_design_scores_gemma":[0.000013886836,0.000007760438,0.00018076312,0.00005222671,0.000001633987,0.000042547003,0.00003295978,0.000020880934,0.0000528032,0.0003693954,0.9992186,0.0000063907264],"about_ca_topic_score_codex":0.0057750917,"about_ca_topic_score_gemma":0.007345854,"teacher_disagreement_score":0.39320973,"about_ca_system_score_codex":0.0025438839,"about_ca_system_score_gemma":0.002207481,"threshold_uncertainty_score":0.86551267},"labels":[],"label_agreement":null},{"id":"W4412726223","doi":"10.1111/bph.70139","title":"Comprehensive analysis of extracellular matrix remodelling via cyclophilin inhibition in human models of alcohol‐related liver fibrosis","year":2025,"lang":"en","type":"article","venue":"British Journal of Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"The Metabolomics Innovation Centre","funders":"King's College London; Foundation for Liver Research; Wellcome Trust","keywords":"Extracellular matrix; Hepatic stellate cell; Fibrosis; Cell biology; Transcriptome; Chemistry; Cancer research; Biology; Biochemistry; Pathology; Medicine; Gene expression","score_opus":0.01709929332126135,"score_gpt":0.30418917705706855,"score_spread":0.2870898837358072,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4412726223","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9865362,0.004576719,0.0058363182,0.000161225,0.000042250536,0.000117565585,0.0013815545,0.00013716304,0.0012111033],"genre_scores_gemma":[0.98886126,0.00295274,0.0041199876,0.00012856272,0.000017140488,0.00017645679,0.0018433905,0.00003318894,0.0018674069],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998221,0.000030198931,0.00001257385,0.0000316862,0.00007182838,0.00003166729],"domain_scores_gemma":[0.99985075,0.00002355599,0.00004881701,0.00002047513,0.000025110901,0.000031186446],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003000869,0.00032961936,0.00027744047,0.0004026345,0.00015710155,0.00019307008,0.00013706248,0.00028531224,0.0012106253],"category_scores_gemma":[0.00012779732,0.0001283131,0.00033972482,0.00023493211,0.00024711693,0.00013663435,0.00014268346,0.00046244022,0.00026438604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003824693,0.00004690905,0.0002971438,0.00008343563,0.000015466972,0.000049667557,0.000012994534,0.000088398556,0.9973015,0.000019897312,0.000059517006,0.0016426459],"study_design_scores_gemma":[0.000051676314,0.002493075,0.020306818,0.000016921169,0.00008004196,0.0006528167,0.000062342864,0.0010692709,0.97206503,0.000050339528,0.003142227,0.000009357126],"about_ca_topic_score_codex":0.00047324353,"about_ca_topic_score_gemma":0.0009575493,"teacher_disagreement_score":0.0012106253,"about_ca_system_score_codex":0.00019269912,"about_ca_system_score_gemma":0.00017792301,"threshold_uncertainty_score":0.004049957},"labels":[],"label_agreement":null},{"id":"W4413030776","doi":"10.1101/2025.08.05.668714","title":"Characterization of bacterial fucokinase/GDP-fucose pyrophosphorylase (FKP) enzymes supports the evolution of interdomain communication and modularity in the FKP family","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Queen's University","funders":"","keywords":"Modularity (biology); Characterization (materials science); Computer science; Artificial intelligence; Biology; Physics; Optics; Evolutionary biology","score_opus":0.007216945226759314,"score_gpt":0.2126573418324799,"score_spread":0.20544039660572058,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413030776","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99822134,0.0001394839,0.0011358676,0.000030384825,0.0000018085639,0.0000053066897,0.0001718493,0.000008728401,0.00028532866],"genre_scores_gemma":[0.99796706,0.0001182242,0.0012279336,0.000007057911,0.0000021030226,0.000005851018,0.00044990922,0.0000032218543,0.00021862763],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993753,0.000008858755,0.0000071770287,0.000015358919,0.0000150327905,0.000016060787],"domain_scores_gemma":[0.99989784,0.000020566355,0.000031274765,0.000011541125,0.000016701777,0.000022129045],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00013656153,0.0002513861,0.000120812205,0.00022181426,0.00009190954,0.0002124514,0.0000997091,0.00013970812,0.00038989368],"category_scores_gemma":[0.00024092157,0.00006225652,0.00018919625,0.0002609439,0.00013565835,0.00021272198,0.0001910023,0.00021742165,0.00016314084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006268286,0.000015364583,0.004277153,0.000025689791,0.000004519993,0.00010359327,0.000039632225,0.00018348945,0.99282867,0.00011707508,0.000010265069,0.002331898],"study_design_scores_gemma":[0.000008299326,0.0002160205,0.10156154,0.000012497188,0.00003058973,0.0010271101,0.00023077209,0.0045433985,0.8907314,0.00023137391,0.001396652,0.0000103981365],"about_ca_topic_score_codex":0.00097522774,"about_ca_topic_score_gemma":0.00060981297,"teacher_disagreement_score":0.00097522774,"about_ca_system_score_codex":0.00021298113,"about_ca_system_score_gemma":0.00016857896,"threshold_uncertainty_score":0.0019391775},"labels":[],"label_agreement":null},{"id":"W4413274025","doi":"10.5194/egusphere-2025-297-ac3","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Mathematics","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413274025","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00034984126,0.0014664115,0.0004912501,0.61185217,0.26436138,0.0003302889,0.0022523778,0.0011018332,0.11779446],"genre_scores_gemma":[0.0027235297,0.0008780484,0.00031427166,0.6291885,0.058228776,0.00035917095,0.00085279794,0.0005449153,0.30691007],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9974285,0.00036418915,0.00025509312,0.0003829929,0.0010144974,0.0005548526],"domain_scores_gemma":[0.99276155,0.0018632356,0.0002210736,0.0004334227,0.0035385662,0.0011820963],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0026463545,0.000936472,0.0009778123,0.0010834169,0.0030921295,0.0044624847,0.0024347075,0.02297991,0.3381732],"category_scores_gemma":[0.024383577,0.0005597688,0.0015071292,0.0008957987,0.0017521649,0.0032955268,0.0027026539,0.016224146,0.2441308],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000009648374,0.0000036123133,0.000025153893,0.000012841386,8.277697e-7,0.000024972927,0.0000058993664,0.000003844983,0.000019434514,0.00030946382,0.99773204,0.0018522431],"study_design_scores_gemma":[0.000012488525,0.0000079566835,0.00017088823,0.000054226417,0.0000017634608,0.00003170383,0.000037880374,0.000021053303,0.000052557694,0.0004297492,0.99917126,0.000008466461],"about_ca_topic_score_codex":0.009363791,"about_ca_topic_score_gemma":0.010257027,"teacher_disagreement_score":0.3381732,"about_ca_system_score_codex":0.0038821877,"about_ca_system_score_gemma":0.0037831368,"threshold_uncertainty_score":0.9440156},"labels":[],"label_agreement":null},{"id":"W4413480462","doi":"10.3390/md23090336","title":"Democratized Discovery of Microsclerodermin F as an Immunophilin Ligand","year":2025,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; Medical Research Council; University of California, San Diego; National Institutes of Health; UK Dementia Research Institute; Medical Research Council Canada","keywords":"Computational biology; Drug discovery; Medicine; Chemistry; Biology; Bioinformatics","score_opus":0.004504700921310832,"score_gpt":0.2535915805492152,"score_spread":0.24908687962790438,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413480462","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9363222,0.0035643522,0.04341586,0.0012391453,0.00014176629,0.00018625977,0.00042471863,0.00036601198,0.014339703],"genre_scores_gemma":[0.97311246,0.002205311,0.017868664,0.00028171582,0.000029955036,0.00006937813,0.00020512176,0.000024377438,0.0062031145],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987805,0.000021007443,0.0000054975562,0.000019183322,0.00004883036,0.000027432156],"domain_scores_gemma":[0.99994886,0.0000075461044,0.000012120716,0.0000082010365,0.000008432462,0.00001472667],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024259639,0.00016747508,0.00014702928,0.00020231589,0.00011458179,0.0003122459,0.00017373885,0.00030874784,0.0011825693],"category_scores_gemma":[0.00015507668,0.000088286666,0.00013384178,0.000121867415,0.00021552751,0.00020722073,0.00035222902,0.00045679466,0.00036587645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000093718765,0.00007054154,0.00033867883,0.00005769145,0.000015960193,0.00018914025,0.000034996905,0.001599878,0.9756501,0.0060999556,0.000496561,0.015352882],"study_design_scores_gemma":[0.000042929718,0.00056234526,0.0011950646,0.0000096200665,0.000014216913,0.000322816,0.000025365884,0.0035785348,0.971133,0.00074882654,0.022352159,0.0000150437445],"about_ca_topic_score_codex":0.0003749157,"about_ca_topic_score_gemma":0.00090569287,"teacher_disagreement_score":0.0011825693,"about_ca_system_score_codex":0.0003901889,"about_ca_system_score_gemma":0.00033627567,"threshold_uncertainty_score":0.00395602},"labels":[],"label_agreement":null},{"id":"W4413768144","doi":"10.1101/2025.08.26.669098","title":"A modified cyclosporine enhances lentivector transduction <i>ex vivo</i> and <i>in vivo</i> by degrading IFITM3","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Institute of Infection and Immunity","funders":"UCLH Biomedical Research Centre; Medical Research Council; University College London Hospitals NHS Foundation Trust; National Institute for Health and Care Research; Rosetrees Trust; Anthony Nolan; Wellcome Trust","keywords":"In vivo; Ex vivo; Transduction (biophysics); Biology; Cell biology; Genetics; Biophysics","score_opus":0.009006080937395763,"score_gpt":0.2205677985762754,"score_spread":0.21156171763887963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413768144","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9662161,0.0025381602,0.01297296,0.0005055059,0.00032919284,0.00012947388,0.0016804284,0.00073353347,0.014894687],"genre_scores_gemma":[0.9630893,0.0013550302,0.012045287,0.00022463674,0.0000634656,0.00005858681,0.0014986907,0.00023264643,0.021432394],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993134,0.000009171986,0.000007395321,0.000010030308,0.00003193248,0.0000101753285],"domain_scores_gemma":[0.99993813,0.000014803366,0.000020163627,0.0000057748493,0.0000093444005,0.000011826022],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012222832,0.00016090459,0.00011983591,0.00017048969,0.000110083485,0.00018226613,0.000117609714,0.00021491745,0.0027610653],"category_scores_gemma":[0.00008826066,0.00006548106,0.00017015755,0.00011357111,0.00012080897,0.0000913053,0.000076273944,0.00022234638,0.00065472437],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000090616944,0.000010907295,0.00007732981,0.00004066842,0.0000020513264,0.00003938836,0.000005207384,0.00004870135,0.99731344,0.00013215392,0.00027342924,0.0019661859],"study_design_scores_gemma":[0.000008188042,0.00006448439,0.00063351146,0.00000249887,0.000003717231,0.00009873382,0.0000025728355,0.00020338641,0.9953015,0.0000154536,0.0036643664,0.0000016261046],"about_ca_topic_score_codex":0.00048186557,"about_ca_topic_score_gemma":0.00067576714,"teacher_disagreement_score":0.0027610653,"about_ca_system_score_codex":0.00023069183,"about_ca_system_score_gemma":0.00018114256,"threshold_uncertainty_score":0.009236693},"labels":[],"label_agreement":null},{"id":"W4413787922","doi":"10.1016/j.jbc.2025.110646","title":"CLIC5A binds to and stabilizes the open and active conformation of ezrin","year":2025,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Canadian Federation of University Women","keywords":"Ezrin; Chemistry; Biophysics; Cell biology; Stereochemistry; Crystallography; Biochemistry; Biology; Cell","score_opus":0.021567500625368056,"score_gpt":0.3066939068425416,"score_spread":0.28512640621717356,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413787922","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99266994,0.0021404042,0.0026445608,0.00011834732,0.000022457487,0.000016558984,0.00035569235,0.000082223276,0.0019497619],"genre_scores_gemma":[0.9954554,0.00035175384,0.0011294954,0.0000825688,0.000005835391,0.0000099017425,0.000732172,0.000011188655,0.002221753],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998217,0.000016846103,0.000013019546,0.000057963432,0.000040463994,0.00005012319],"domain_scores_gemma":[0.99991345,0.000008044759,0.000023665778,0.000008881907,0.0000147719475,0.000031100128],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012115252,0.00031522824,0.0002222332,0.00028442545,0.00036567962,0.00036238533,0.00024774493,0.0004006151,0.0022770965],"category_scores_gemma":[0.00012735475,0.00013252383,0.00034848796,0.00018765422,0.00022375832,0.00019789134,0.00030093952,0.00037696568,0.00085397286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009839751,0.0000114395,0.0006820787,0.000042675925,0.000008418178,0.00010024316,0.0000151608165,0.00007370364,0.99736637,0.0001568371,0.00009850962,0.001346113],"study_design_scores_gemma":[0.000022095783,0.00014307018,0.02113589,0.000016956892,0.00002303245,0.00053366093,0.00006996164,0.0021169141,0.96706957,0.000094839525,0.008764392,0.0000095156565],"about_ca_topic_score_codex":0.0013575824,"about_ca_topic_score_gemma":0.0018169198,"teacher_disagreement_score":0.0022770965,"about_ca_system_score_codex":0.0007631305,"about_ca_system_score_gemma":0.00016770454,"threshold_uncertainty_score":0.0076176524},"labels":[],"label_agreement":null},{"id":"W4414138822","doi":"10.5194/egusphere-2025-2707-ac1","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Glacier; Digital elevation model; Ice caps; Elevation (ballistics); Glacier terminus; Glacier mass balance; Tidewater glacier cycle; Cryosphere","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414138822","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021315602,0.0014935399,0.00025100427,0.7035083,0.2647756,0.00011399196,0.0011274029,0.0005197795,0.02799717],"genre_scores_gemma":[0.0031694733,0.0016956208,0.00032573077,0.69534254,0.116391964,0.0001740339,0.0007176849,0.00038628827,0.18179666],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9980392,0.00028196862,0.00021322933,0.00029918662,0.00084036135,0.0003262043],"domain_scores_gemma":[0.98937607,0.0028561468,0.0003440318,0.00041712256,0.0053873165,0.0016193979],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0021309704,0.0007940113,0.0009559906,0.0014615579,0.0025025143,0.0032063457,0.0023316348,0.015748015,0.1964066],"category_scores_gemma":[0.030159796,0.00044800545,0.0010094782,0.0009816482,0.0017799117,0.00273326,0.0020750181,0.0132787535,0.117940135],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000007759144,0.0000018484465,0.000026999218,0.000010135807,7.201267e-7,0.00003511938,0.000005055066,0.0000028092084,0.000011473682,0.00011972156,0.99827754,0.0015007993],"study_design_scores_gemma":[0.000012645392,0.0000063807056,0.00024217111,0.000055341003,0.0000026270454,0.00007306984,0.000045928107,0.000025367905,0.000051924042,0.00034183988,0.9991314,0.000011315017],"about_ca_topic_score_codex":0.015045823,"about_ca_topic_score_gemma":0.019340929,"teacher_disagreement_score":0.8035934,"about_ca_system_score_codex":0.0035269544,"about_ca_system_score_gemma":0.0036726051,"threshold_uncertainty_score":0.65704554},"labels":[],"label_agreement":null},{"id":"W4414224063","doi":"10.5194/egusphere-2025-2991-ac2","title":"Reply on CC1","year":2025,"lang":"en","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Ceilometer; Smoke; HYSPLIT; Plume; Air quality index; Satellite; Particulates; Aerosol","score_opus":0.022440212224498848,"score_gpt":0.31873521195373616,"score_spread":0.29629499972923734,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414224063","genre_codex":"commentary","genre_gemma":"commentary","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"commentary","genre_consensus":"commentary","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00041466925,0.0019459397,0.0004485006,0.59483784,0.28743833,0.00033294724,0.0018580811,0.0012103709,0.11151329],"genre_scores_gemma":[0.004079064,0.0012856654,0.00033505357,0.51652825,0.08055817,0.00030189994,0.0007717352,0.0004630226,0.39567706],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99848145,0.00025804897,0.00015558716,0.00025337757,0.0005527371,0.0002988289],"domain_scores_gemma":[0.9949852,0.001333635,0.00018603663,0.00027443114,0.0022052603,0.0010155401],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0015907737,0.0008228567,0.0009031013,0.0010363163,0.0023700013,0.0034567679,0.002335037,0.016373876,0.38577175],"category_scores_gemma":[0.02044831,0.0004391276,0.0010978684,0.0006412465,0.0013822733,0.0027497816,0.0025342687,0.012986134,0.24280804],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011824443,0.000004024238,0.000033982942,0.000012717889,8.463755e-7,0.00004790247,0.000006248813,0.0000041657445,0.000015745482,0.00019785935,0.99686265,0.002801996],"study_design_scores_gemma":[0.000013432621,0.000009711706,0.0001945851,0.00005546542,0.0000018232829,0.00007014543,0.00005253279,0.00003012777,0.00005228987,0.00040125372,0.9991103,0.000008277397],"about_ca_topic_score_codex":0.0053635226,"about_ca_topic_score_gemma":0.0068510873,"teacher_disagreement_score":0.38577175,"about_ca_system_score_codex":0.002385064,"about_ca_system_score_gemma":0.0022131084,"threshold_uncertainty_score":0.87612206},"labels":[],"label_agreement":null},{"id":"W4414260588","doi":"10.1101/2025.09.09.674382","title":"CD155 regulates tumor growth and immune evasion in diffuse midline glioma","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University Health Centre; University of Calgary","funders":"","keywords":"Gene silencing; Immune system; Glioma; Apoptosis; Evasion (ethics); Immune checkpoint; Immunotherapy","score_opus":0.007891171345330353,"score_gpt":0.21569124112112226,"score_spread":0.2078000697757919,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414260588","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99570787,0.002009593,0.00054850534,0.000068685644,0.00001076534,0.0000099824765,0.00020256007,0.000037351503,0.0014045573],"genre_scores_gemma":[0.9982828,0.00047419211,0.0002555586,0.000028462448,0.000002895977,0.000005930067,0.00017570402,0.0000043657074,0.0007701637],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99995315,0.000006325625,0.0000026952448,0.000011242863,0.000011331032,0.000015198717],"domain_scores_gemma":[0.99997115,0.0000030191782,0.000011332101,0.0000017802606,0.0000026080263,0.000010160752],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005032322,0.00021348253,0.00011357988,0.00018149457,0.00009449397,0.00022463537,0.00008326665,0.00018752115,0.0007736776],"category_scores_gemma":[0.000060364055,0.000063557454,0.000089863046,0.00009585301,0.00013896846,0.00008879698,0.00011456539,0.00025187532,0.00025812353],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011144753,0.000013366417,0.0011460566,0.000032557506,0.0000036077126,0.00019178884,0.00001160006,0.00007480173,0.99662197,0.00013977426,0.000120037046,0.0015330982],"study_design_scores_gemma":[0.000048870195,0.0004517899,0.05748117,0.00001940464,0.00003474148,0.0020969757,0.00014621633,0.0019454476,0.9275837,0.00015778275,0.010026825,0.00000706123],"about_ca_topic_score_codex":0.0006094252,"about_ca_topic_score_gemma":0.00081017194,"teacher_disagreement_score":0.0007736776,"about_ca_system_score_codex":0.00036782146,"about_ca_system_score_gemma":0.0001341648,"threshold_uncertainty_score":0.0026687384},"labels":[],"label_agreement":null},{"id":"W4414350130","doi":"10.1158/1538-7445.ovarian25-a011","title":"Abstract A011: PAX8-dependent signaling networks as drivers of progression and immune evasion in high grade serous ovarian cancer","year":2025,"lang":"en","type":"article","venue":"Cancer Research","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"PAX8; Tumor progression; Neuroblastoma RAS viral oncogene homolog; Tumor microenvironment; SMAD; Transcription factor; Ovarian cancer; MHC class I; Immune system","score_opus":0.032402602929779,"score_gpt":0.38505489274572363,"score_spread":0.35265228981594465,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414350130","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9910329,0.0024713979,0.0023873642,0.00024138992,0.000030156494,0.000025268164,0.0004524072,0.00008836807,0.003270812],"genre_scores_gemma":[0.9953744,0.00080247934,0.0006312049,0.000046988876,0.000007807333,0.000017033457,0.00033110453,0.0000075353464,0.0027815043],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9999392,0.0000073234405,0.000004031626,0.000014572209,0.000020368767,0.000014423055],"domain_scores_gemma":[0.9999491,0.000006520504,0.000019298659,0.0000035949183,0.0000068719482,0.000014572797],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000994826,0.00017935636,0.00011479602,0.00027660347,0.00015602088,0.00035976924,0.00010850169,0.00020400717,0.0027436765],"category_scores_gemma":[0.00007392812,0.0000815785,0.0001351816,0.00019299627,0.00019532333,0.00026521916,0.00023297897,0.0003659701,0.00037106586],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002870174,0.00002629647,0.003848815,0.00010335425,0.000009412275,0.00022038017,0.000042926273,0.0001442416,0.9877033,0.0007462275,0.00017380135,0.006694131],"study_design_scores_gemma":[0.00006117606,0.0006875839,0.07597969,0.000046130226,0.00006141339,0.0018285167,0.00044331898,0.004568099,0.89471436,0.001068487,0.020528773,0.0000124937],"about_ca_topic_score_codex":0.0002277202,"about_ca_topic_score_gemma":0.0003174401,"teacher_disagreement_score":0.0027436765,"about_ca_system_score_codex":0.00022623347,"about_ca_system_score_gemma":0.00012618185,"threshold_uncertainty_score":0.009178579},"labels":[],"label_agreement":null},{"id":"W4414476958","doi":"10.54254/2753-8818/2025.au27080","title":"CTNNA3 and MBP Mediate Treatment Resistance Through Tumor Microenvironment Remodeling in Recurrent Glioblastoma","year":2025,"lang":"en","type":"article","venue":"Theoretical and Natural Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Milton District Hospital","funders":"","keywords":"Extracellular matrix; Tumor microenvironment; Glioblastoma; Primary tumor; Population; Disease; Brain tumor; Mechanism (biology)","score_opus":0.0038521005102374437,"score_gpt":0.25000562540507454,"score_spread":0.2461535248948371,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414476958","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9991835,0.00042198537,0.00017073752,0.000021043785,0.0000021122291,0.000002771692,0.000025832069,0.000008821626,0.0001632282],"genre_scores_gemma":[0.9996166,0.00015016398,0.00007845189,0.000011219515,0.0000015114787,0.00000393273,0.000031526313,0.0000017845309,0.000104698775],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999274,0.000013675278,0.0000048668535,0.0000097654165,0.000020540578,0.0000238018],"domain_scores_gemma":[0.99993944,0.000008922056,0.000023977518,0.0000054503084,0.0000066698003,0.000015488004],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012028204,0.00010632023,0.00018717012,0.00017306609,0.000100012774,0.00024257097,0.00009889975,0.00014361645,0.0003780253],"category_scores_gemma":[0.00016893071,0.00007698039,0.00009033137,0.00011912747,0.00017674362,0.00009681933,0.00012626575,0.00018541375,0.00008452418],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041030117,0.000050452552,0.006461401,0.00002802695,0.000013527097,0.0002045362,0.00007215921,0.00020763595,0.9880676,0.00011649887,0.000060204857,0.0043077217],"study_design_scores_gemma":[0.0000491027,0.0016021137,0.32208866,0.000011461135,0.0000839999,0.002350307,0.00036325032,0.0059324987,0.66482484,0.00047456028,0.002203311,0.00001579793],"about_ca_topic_score_codex":0.0011894851,"about_ca_topic_score_gemma":0.0016517342,"teacher_disagreement_score":0.0011894851,"about_ca_system_score_codex":0.00024571994,"about_ca_system_score_gemma":0.00015012042,"threshold_uncertainty_score":0.0023651123},"labels":[],"label_agreement":null},{"id":"W4414624975","doi":"10.1093/bib/bbaf501","title":"A simple workflow to identify novel small linear motif (SLiM)-mediated interactions with AlphaFold","year":2025,"lang":"en","type":"article","venue":"Briefings in Bioinformatics","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Fonds De La Recherche Scientifique - FNRS; European Orthodontic Society","keywords":"Workflow; Scalability; Benchmark (surveying); Metric (unit); Protein–protein interaction; Degeneracy (biology)","score_opus":0.016164437302357473,"score_gpt":0.290631053144736,"score_spread":0.2744666158423785,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414624975","genre_codex":"empirical","genre_gemma":"methods","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"methods","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.53720576,0.0017140626,0.3438904,0.0005903373,0.0002467064,0.001553372,0.044323318,0.06054486,0.009931171],"genre_scores_gemma":[0.4725554,0.0007210939,0.46026054,0.0005279677,0.00003894566,0.0018591149,0.056741383,0.002001011,0.0052945344],"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","domain_scores_codex":[0.9992772,0.000067574496,0.00006954913,0.000303341,0.0001956801,0.00008661145],"domain_scores_gemma":[0.99932814,0.00020041462,0.000095212774,0.00014390802,0.00014197043,0.00009033455],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009612275,0.0013308979,0.0008378557,0.0013222699,0.0007063305,0.0011121983,0.0007713182,0.0006534873,0.0050056893],"category_scores_gemma":[0.0021230127,0.00034751077,0.0011079209,0.0007489064,0.00037624047,0.0006378988,0.0011457741,0.00078021275,0.002925954],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.001386712,0.00036642954,0.029843468,0.0017220466,0.00029027133,0.0009217855,0.0003086173,0.016070895,0.7686725,0.0029661201,0.022765271,0.15468585],"study_design_scores_gemma":[0.00019774283,0.0010426671,0.031000016,0.00012715544,0.00016810054,0.0017432786,0.00029336778,0.1728416,0.73916763,0.0054848813,0.047760792,0.00017271367],"about_ca_topic_score_codex":0.001118687,"about_ca_topic_score_gemma":0.0022097519,"teacher_disagreement_score":0.0050056893,"about_ca_system_score_codex":0.000444727,"about_ca_system_score_gemma":0.0011437513,"threshold_uncertainty_score":0.016745687},"labels":[],"label_agreement":null},{"id":"W4414913305","doi":"10.3390/biomedicines13102442","title":"Cyclophilin Inhibitor Rencofilstat Combined with Proteasome Inhibitor Ixazomib Increases Proteotoxic Cell Death in Advanced Prostate Cancer Cells with Minimal Effects on Non-Cancer Cells","year":2025,"lang":"en","type":"article","venue":"Biomedicines","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"NAEJA-RGM Pharmaceuticals (Canada)","funders":"National Cancer Institute; Geriatric Research Education and Clinical Center; NIH Clinical Center; National Institutes of Health; U.S. Department of Veterans Affairs","keywords":"Ixazomib; Prostate cancer; Proteasome inhibitor; Programmed cell death; Cancer cell; Syngenic; Apoptosis; Cancer","score_opus":0.004092825607968657,"score_gpt":0.24005143279975863,"score_spread":0.23595860719178996,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414913305","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9915379,0.004405832,0.0009645779,0.00014139172,0.000075179414,0.00004229677,0.00059330417,0.00016300273,0.0020765157],"genre_scores_gemma":[0.9927087,0.002595564,0.0010503932,0.000052871386,0.000017112588,0.000037388236,0.0007251871,0.000012436513,0.0028002711],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993503,0.0000060044454,0.000004892793,0.000013077895,0.000020639545,0.000020408621],"domain_scores_gemma":[0.99996126,0.0000043359596,0.000009959918,0.0000036644612,0.000005773403,0.000014999994],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005324455,0.0002815204,0.00026839148,0.00018622345,0.00009550758,0.00015899603,0.000110794535,0.00012075795,0.0016845608],"category_scores_gemma":[0.000036169928,0.000079764686,0.00019717355,0.00015492446,0.00010453929,0.00009079599,0.00008997469,0.0004200111,0.000212738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00051520846,0.00011272757,0.0003246831,0.000118280994,0.000017356517,0.00004720961,0.00001379592,0.00016264133,0.9953793,0.00005612073,0.0002460267,0.0030066937],"study_design_scores_gemma":[0.00005469116,0.0013353656,0.0059556672,0.000008109363,0.00003852943,0.00017858797,0.000022392527,0.0005990826,0.9878984,0.000016732853,0.0038877109,0.0000047319813],"about_ca_topic_score_codex":0.0011423271,"about_ca_topic_score_gemma":0.002245515,"teacher_disagreement_score":0.0016845608,"about_ca_system_score_codex":0.00021908728,"about_ca_system_score_gemma":0.0002588935,"threshold_uncertainty_score":0.0056353807},"labels":[],"label_agreement":null},{"id":"W4414967695","doi":"10.1101/2025.10.02.680088","title":"Promoter hijacking by primate LINC00473 disrupts an ancestral CREB-PDE10A feedback loop","year":2025,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; University of Prince Edward Island","funders":"Innovation PEI","keywords":"Gene; Regulation of gene expression; Gene expression; Function (biology); Promoter; Homologous chromosome; HEK 293 cells; Conserved sequence","score_opus":0.01428282968604486,"score_gpt":0.2591499670947769,"score_spread":0.24486713740873203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4414967695","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.88314056,0.00616881,0.056689963,0.004165335,0.0014530469,0.00020190545,0.010707116,0.0049968865,0.032476377],"genre_scores_gemma":[0.95775795,0.002140914,0.015129822,0.0005775737,0.00007523249,0.00009515958,0.003677895,0.00030786486,0.020237602],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998883,0.000011717037,0.0000057539964,0.00003524935,0.00003678881,0.000022138966],"domain_scores_gemma":[0.99993443,0.000009435346,0.000022735421,0.0000070781466,0.0000069401044,0.000019401014],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016231844,0.00037794583,0.0002622258,0.0002265227,0.0002572452,0.0003769274,0.00033400653,0.00048312158,0.0085335765],"category_scores_gemma":[0.0001240258,0.00018679466,0.0003559829,0.00019808595,0.00037867922,0.000269548,0.00035526315,0.0013718695,0.0016239362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000101106125,0.000016262922,0.0002512952,0.00013960485,0.000011258565,0.00017462643,0.000019210967,0.00027866714,0.9927046,0.0009251769,0.0011125159,0.0042657144],"study_design_scores_gemma":[0.000046344827,0.00016308136,0.0035649796,0.000030365458,0.00004444824,0.00039974166,0.000054864166,0.0027342848,0.95837975,0.00070940284,0.033851642,0.000021073896],"about_ca_topic_score_codex":0.0010188518,"about_ca_topic_score_gemma":0.0016368508,"teacher_disagreement_score":0.0085335765,"about_ca_system_score_codex":0.00057886884,"about_ca_system_score_gemma":0.00033960518,"threshold_uncertainty_score":0.028547645},"labels":[],"label_agreement":null},{"id":"W4415300241","doi":"10.5194/egusphere-2025-3999-ac2","title":"Reply on CC1","year":2025,"lang":"","type":"peer-review","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Deep water; North Atlantic Deep Water; Biogeochemical cycle; Water mass; Current (fluid); Estuary; Deep sea","score_opus":0.02109303689008538,"score_gpt":0.31475129831923226,"score_spread":0.29365826142914686,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415300241","genre_codex":"commentary","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00021538236,0.0016688947,0.00022600546,0.7329387,0.22561301,0.00012353268,0.00085202034,0.00053429743,0.0378281],"genre_scores_gemma":[0.0025920924,0.0010960846,0.00020729365,0.75660145,0.07822791,0.00017352849,0.00038504394,0.00026241396,0.16045436],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99825305,0.00030274008,0.00018696512,0.00030728476,0.00063959474,0.00031028464],"domain_scores_gemma":[0.9939476,0.001933881,0.00024616907,0.00031167397,0.0024613095,0.0010992787],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0020684504,0.0008896226,0.0010551699,0.0012407913,0.0027854592,0.0037086497,0.0029186904,0.02211001,0.23079015],"category_scores_gemma":[0.022527853,0.0005851358,0.0012445144,0.0008551609,0.0019226082,0.0034611446,0.0027544154,0.018745873,0.1482447],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000008727712,0.000002295076,0.000025688527,0.000011315242,8.341693e-7,0.000043649965,0.0000063543857,0.0000032123262,0.000012944083,0.0001942143,0.99799037,0.0017004895],"study_design_scores_gemma":[0.000014415915,0.0000071299055,0.00020162809,0.00006410047,0.0000023103328,0.00007931014,0.000054201366,0.000027098084,0.000049204467,0.00048720694,0.999003,0.000010455705],"about_ca_topic_score_codex":0.007224565,"about_ca_topic_score_gemma":0.0097023025,"teacher_disagreement_score":0.76920986,"about_ca_system_score_codex":0.0032326241,"about_ca_system_score_gemma":0.00275402,"threshold_uncertainty_score":0.77207},"labels":[],"label_agreement":null},{"id":"W4415351739","doi":"10.1016/j.bioorg.2026.109958","title":"In silico and in vitro characterization of VC15, a short peptide derived from Pin2","year":2025,"lang":"en","type":"article","venue":"Bioorganic Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"CYTED Ciencia y Tecnología para el Desarrollo","keywords":"Peptide; In silico; Hemolysis; Liposome; In vitro; Antimicrobial; Transmembrane protein; Antimicrobial peptides; Membrane","score_opus":0.00586366112494116,"score_gpt":0.22295355367684738,"score_spread":0.21708989255190622,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4415351739","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9846133,0.001976386,0.010343767,0.000087428605,0.00006165713,0.00006672132,0.0010321044,0.000049620634,0.0017690217],"genre_scores_gemma":[0.97928864,0.0009836705,0.012863534,0.00009774941,0.000015409212,0.000042336014,0.0042535146,0.00003673551,0.0024183744],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99979943,0.00003978353,0.000013283865,0.000049084607,0.000058125934,0.00004038468],"domain_scores_gemma":[0.99983454,0.000060586135,0.000027685946,0.000012574197,0.0000255935,0.000038949984],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00036810173,0.0005139479,0.00036448997,0.00022479243,0.0002021811,0.0005806313,0.00035442386,0.00033201024,0.0012413599],"category_scores_gemma":[0.0004365395,0.00015591411,0.00045463975,0.00021740404,0.00021702649,0.00021885427,0.00022263384,0.0005823314,0.0005640752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002569588,0.00006115933,0.00058184617,0.00011697486,0.000022455102,0.00020178645,0.0000325183,0.0027595013,0.9930266,0.0002109696,0.000082407496,0.0026466993],"study_design_scores_gemma":[0.000023122775,0.00037419162,0.0012630618,0.000011648015,0.00004180052,0.0003882609,0.000043739354,0.005328298,0.98752975,0.00007570648,0.004904531,0.00001603436],"about_ca_topic_score_codex":0.00087721,"about_ca_topic_score_gemma":0.000862383,"teacher_disagreement_score":0.0012413599,"about_ca_system_score_codex":0.00033644467,"about_ca_system_score_gemma":0.00042708882,"threshold_uncertainty_score":0.004152775},"labels":[],"label_agreement":null},{"id":"W4416076177","doi":"10.1136/jitc-2025-sitc2025.1161","title":"1161 Novel cyclophilin inhibitors could serve as an NK cell-stimulating immunotherapy for triple negative breast cancer","year":2025,"lang":"","type":"article","venue":"Regular and Young Investigator Award Abstracts","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Institute of Genetics; International Seafood Sustainability Foundation","keywords":"Immunotherapy; Triple-negative breast cancer; Cyclophilin A; Cancer immunotherapy; Breast cancer","score_opus":0.012852219179175036,"score_gpt":0.2814946952335048,"score_spread":0.2686424760543297,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4416076177","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93920845,0.038539667,0.005967276,0.0009725887,0.000416049,0.000297765,0.00088238483,0.00023910057,0.013476653],"genre_scores_gemma":[0.976661,0.011173992,0.0026577031,0.00031652985,0.00006485014,0.00014676692,0.0009742844,0.000017070857,0.007987783],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99996614,0.0000058319124,0.000002910959,0.0000055087626,0.000008825741,0.000010830316],"domain_scores_gemma":[0.9999832,0.000002499465,0.0000039583906,0.0000013229048,0.0000037116793,0.0000053532603],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000059316935,0.00024854625,0.00020582325,0.0001433677,0.00007949884,0.0002608909,0.00012931676,0.00024234857,0.0025593245],"category_scores_gemma":[0.00005399651,0.000058918078,0.00019949426,0.0000915619,0.00009183884,0.00012569274,0.000119198616,0.00034633695,0.0005137745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00069396757,0.00018390143,0.00090519886,0.00037935536,0.000037428385,0.00021931336,0.000020897201,0.00043701753,0.9562891,0.0004406413,0.0013377833,0.03905539],"study_design_scores_gemma":[0.00035158504,0.003618633,0.009936897,0.0000711414,0.00017779341,0.0017472868,0.000043264405,0.0029969325,0.92306656,0.00030189386,0.057670407,0.000017680248],"about_ca_topic_score_codex":0.00020413558,"about_ca_topic_score_gemma":0.0005242837,"teacher_disagreement_score":0.0025593245,"about_ca_system_score_codex":0.00015595232,"about_ca_system_score_gemma":0.000120312325,"threshold_uncertainty_score":0.00856185},"labels":[],"label_agreement":null},{"id":"W4417295603","doi":"10.1186/s13024-025-00917-x","title":"Targeted deletion of EMMPRIN in microglia/macrophages mitigates neuronal death in intracerebral hemorrhage","year":2025,"lang":"en","type":"article","venue":"Molecular Neurodegeneration","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland; Hotchkiss Brain Institute; Alberta Bone and Joint Health Institute; University of Calgary","funders":"Canadian Institutes of Health Research; National Natural Science Foundation of China","keywords":"Neurotoxicity; Intracerebral hemorrhage; Microglia; Matrix metalloproteinase; Gene knockdown; Inflammation; Neurogenesis; Stroke (engine)","score_opus":0.005596010443765161,"score_gpt":0.23720832191094499,"score_spread":0.23161231146717984,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4417295603","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928474,0.0016675519,0.0038557658,0.00012944068,0.00003629584,0.000059206737,0.00016308918,0.00013465466,0.0011066867],"genre_scores_gemma":[0.99367934,0.0014830697,0.002548398,0.000071132854,0.00001909289,0.00010600078,0.00021169294,0.000019851912,0.0018614045],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99987257,0.00001810111,0.000011639838,0.000018734567,0.000034555258,0.000044352484],"domain_scores_gemma":[0.9999157,0.000005749481,0.00003308229,0.000008401936,0.000010943423,0.000026044036],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00019625,0.00047744092,0.00042186092,0.00027586028,0.00016605304,0.00023976938,0.00024483082,0.00032404793,0.0006704684],"category_scores_gemma":[0.00011275167,0.00011672751,0.00018655046,0.00011664574,0.00034803743,0.0002470041,0.00023075147,0.0005928518,0.00021687715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004471631,0.00012127404,0.00017824753,0.00009335597,0.000013538681,0.00008245136,0.000015887272,0.00012033143,0.99608934,0.00012220936,0.00008305953,0.0026332089],"study_design_scores_gemma":[0.000068940484,0.0013614938,0.004702761,0.000021197658,0.000065210246,0.0002404055,0.000038582555,0.00089401845,0.99046504,0.000104166145,0.0020322166,0.000005937379],"about_ca_topic_score_codex":0.00023064522,"about_ca_topic_score_gemma":0.0004909292,"teacher_disagreement_score":0.0006704684,"about_ca_system_score_codex":0.00028166754,"about_ca_system_score_gemma":0.00023080582,"threshold_uncertainty_score":0.0022429228},"labels":[],"label_agreement":null},{"id":"W52358822","doi":"10.1161/circ.116.suppl_16.ii_268-b","title":"Abstract 1312: Dietary Supplementation With Sodium Valproate Attenuates Lesion Development In Hyperglycemic Apolipoprotein E-deficient Mice","year":2007,"lang":"en","type":"article","venue":"Circulation","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Medicine; Endocrinology; Internal medicine; Valproic Acid; Diabetes mellitus; Apolipoprotein B; Streptozotocin; Oxidative stress; Inflammation; Cholesterol; Epilepsy","score_opus":0.02562943948042328,"score_gpt":0.26984961932531876,"score_spread":0.24422017984489547,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W52358822","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98492765,0.0016328086,0.003017398,0.00072888884,0.00027791766,0.000195136,0.0038079154,0.0009511644,0.0044610626],"genre_scores_gemma":[0.9600916,0.002316439,0.0069061844,0.0006701927,0.0001296061,0.00047945254,0.0054874416,0.00041793176,0.023501238],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9995648,0.000060145107,0.000065002605,0.00008997621,0.00011713029,0.0001028189],"domain_scores_gemma":[0.9994104,0.000032067604,0.0001971484,0.000043658583,0.000050485418,0.0002662043],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003057031,0.00132699,0.0010900742,0.0010253505,0.00031350914,0.00074041774,0.00068988506,0.0012560944,0.0039002614],"category_scores_gemma":[0.00022957039,0.0005890252,0.0006660675,0.00039017625,0.00059866393,0.00047152414,0.00033823325,0.001835486,0.0018943171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0027657195,0.0005604948,0.00019942295,0.000089096415,0.00003280138,0.00010782107,0.00002700248,0.00008908257,0.99386483,0.00010087795,0.0002465922,0.0019161812],"study_design_scores_gemma":[0.00089807156,0.0064911996,0.006723532,0.00006795159,0.00011113847,0.0004895025,0.000099635094,0.0013134028,0.97711724,0.00019517132,0.0064567327,0.0000364823],"about_ca_topic_score_codex":0.0013076669,"about_ca_topic_score_gemma":0.0016041236,"teacher_disagreement_score":0.0039002614,"about_ca_system_score_codex":0.00053185096,"about_ca_system_score_gemma":0.0006704875,"threshold_uncertainty_score":0.013047695},"labels":[],"label_agreement":null},{"id":"W606278942","doi":"10.71781/27667","title":"Modulation par le récepteur neurokinine-1du mécanisme d’action des immunosuppresseurs chez les cellules T","year":2012,"lang":"fr","type":"dissertation","venue":"Open MIND","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Molecular biology; Medicine; Biology","score_opus":0.056507199090692545,"score_gpt":0.3087730937320866,"score_spread":0.25226589464139404,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W606278942","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9811489,0.009192925,0.004158929,0.0003273388,0.00011812405,0.000057218982,0.00041222895,0.000068926776,0.004515488],"genre_scores_gemma":[0.9846469,0.005301336,0.002929657,0.00022314646,0.00003905226,0.00012372577,0.0003614447,0.000014540724,0.0063602347],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9998012,0.000030848227,0.000017565026,0.000042305423,0.000045322988,0.00006288593],"domain_scores_gemma":[0.9999156,0.000016924274,0.000021108004,0.000008406407,0.000014477617,0.000023598712],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016107991,0.00022595753,0.0003475866,0.00013457533,0.0002861166,0.00072109606,0.00014748829,0.0002566252,0.0023449967],"category_scores_gemma":[0.00015428774,0.00011351655,0.0003592664,0.00013790806,0.00022392435,0.00032346396,0.00018711857,0.00065367407,0.0004974742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00025193393,0.000028498958,0.000407324,0.000109029825,0.000008780159,0.00006144812,0.000029781439,0.00009050147,0.99616784,0.0002099025,0.000074362026,0.0025605476],"study_design_scores_gemma":[0.000039942857,0.0006659727,0.0099263955,0.000019752491,0.000049913862,0.00035334146,0.00014231318,0.0010293071,0.9790852,0.00010279567,0.008573262,0.000011809315],"about_ca_topic_score_codex":0.0015726553,"about_ca_topic_score_gemma":0.0016371001,"teacher_disagreement_score":0.0023449967,"about_ca_system_score_codex":0.00043064947,"about_ca_system_score_gemma":0.0004270664,"threshold_uncertainty_score":0.007844806},"labels":[],"label_agreement":null},{"id":"W6912733466","doi":"10.5281/zenodo.7468593","title":"Purification of MFSD10 (Tetrana) from Expi293FTM Cells","year":2022,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"European Commission","keywords":"Solubilization; Transporter; Transfection; Proteolysis; Cell culture; Recombinant DNA","score_opus":0.023917225366722392,"score_gpt":0.22763519044971672,"score_spread":0.20371796508299433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6912733466","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.34458068,0.0167995,0.40164635,0.0029648857,0.004170049,0.005069002,0.15877426,0.022485377,0.04350999],"genre_scores_gemma":[0.26154503,0.00839389,0.24484058,0.0015495223,0.0004858276,0.0047868323,0.37809408,0.005841953,0.0944623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991689,0.0000786061,0.000109314184,0.00023392482,0.00027205507,0.00013719793],"domain_scores_gemma":[0.9995789,0.000089305286,0.00003300941,0.00011411672,0.0001098939,0.00007487384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010048216,0.0012263563,0.0017345324,0.0009968536,0.00097644667,0.0012927534,0.0018551315,0.0013120157,0.010361857],"category_scores_gemma":[0.0010887427,0.00081116956,0.00101906,0.0011928327,0.0005323848,0.00071814476,0.0010315414,0.0034382362,0.023174964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013512453,0.00007593719,0.00026031357,0.00042245848,0.000020404974,0.00015010363,0.00012757584,0.00015604334,0.9839627,0.0007597729,0.006022551,0.007907014],"study_design_scores_gemma":[0.0001372718,0.00019483594,0.0031412481,0.000115560935,0.000051820043,0.0008323769,0.00008877891,0.0026449075,0.7904132,0.00071240065,0.20159335,0.00007421095],"about_ca_topic_score_codex":0.0018593143,"about_ca_topic_score_gemma":0.0025782112,"teacher_disagreement_score":0.010361857,"about_ca_system_score_codex":0.0010179557,"about_ca_system_score_gemma":0.00073109113,"threshold_uncertainty_score":0.034663856},"labels":[],"label_agreement":null},{"id":"W6923662536","doi":"10.14288/1.0426811","title":"[Quarles von Ufford Bros. Florists]","year":2023,"lang":"en","type":"other","venue":"cIRcle (University of British Columbia)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Front (military); Portrait; Object (grammar); Period (music)","score_opus":0.007438640563963838,"score_gpt":0.18299373140237193,"score_spread":0.1755550908384081,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6923662536","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0022500039,0.0036905692,0.00020782212,0.009323117,0.0018175928,0.000038527785,0.0008940069,0.00017843074,0.9816],"genre_scores_gemma":[0.0039056162,0.00052232,0.00007386204,0.0008211637,0.000097968485,0.0000084851345,0.00019189238,0.000050301078,0.9943283],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99987435,0.000013500709,0.000002085883,0.00002435545,0.000038879352,0.000046919413],"domain_scores_gemma":[0.99987996,0.000009136359,0.000005838538,0.0000045089846,0.000028112276,0.000072427974],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00015833789,0.0005040524,0.0001898399,0.0006533696,0.004692496,0.0019475521,0.00045558336,0.0012862171,0.30342606],"category_scores_gemma":[0.00024662074,0.0002608439,0.0001716131,0.0007373899,0.00051602727,0.0008231316,0.0009247278,0.0015681598,0.102619],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000015387932,0.0000060856014,0.00027458012,0.00001451594,6.223382e-7,0.00022139792,0.00033306953,0.000016143156,0.00012104146,0.0014865245,0.98233885,0.0151717905],"study_design_scores_gemma":[0.0000010907322,0.0000015039564,0.0005318381,0.000013204666,2.3337746e-7,0.00006515961,0.00033191257,0.0000053027284,0.000012541501,0.00005735714,0.9989785,0.0000014429845],"about_ca_topic_score_codex":0.16903709,"about_ca_topic_score_gemma":0.6368305,"teacher_disagreement_score":0.696574,"about_ca_system_score_codex":0.0015030819,"about_ca_system_score_gemma":0.000827644,"threshold_uncertainty_score":0.9935782},"labels":[],"label_agreement":null},{"id":"W6929415922","doi":"10.5061/dryad.0rxwdbs5h","title":"Glycogen synthase kinase 3 inhibition controls Mycobacterium tuberculosis Infection","year":2024,"lang":"en","type":"dataset","venue":"DRYAD","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"GSK-3; Mycobacterium tuberculosis; Innate immune system; Kinase; Intracellular; Glycogen synthase; Intracellular parasite; Signal transduction; Tyrosine kinase","score_opus":0.008435664554242748,"score_gpt":0.2535730125289241,"score_spread":0.24513734797468137,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929415922","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.004790289,0.0029907245,0.00008841143,0.00015613947,0.000036909005,0.000029889423,0.9898902,0.00023757214,0.0017798226],"genre_scores_gemma":[0.011465212,0.0016341526,0.0005572038,0.00014861496,0.000009499131,0.00016296557,0.98433304,0.00006339295,0.0016258872],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99955183,0.00009004363,0.000047815243,0.0001700804,0.0000717306,0.00006845104],"domain_scores_gemma":[0.99954236,0.00017791953,0.000085454776,0.00005975202,0.0000686024,0.00006590599],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00045378157,0.00091321394,0.0012728106,0.0013268467,0.000372594,0.0011185319,0.0009907287,0.00079116056,0.021593694],"category_scores_gemma":[0.0020451809,0.00022945112,0.0011665667,0.0026754034,0.00019197911,0.00039146625,0.0008641157,0.00065850443,0.009596826],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.003583446,0.00020759697,0.017884973,0.025351727,0.0017140885,0.00025672675,0.00009998995,0.0042003286,0.007770105,0.0015467707,0.88961256,0.04777174],"study_design_scores_gemma":[0.00226127,0.00036277287,0.045620203,0.0017430085,0.0012734166,0.0004124269,0.00013351867,0.0019006169,0.005207311,0.0015946821,0.9394142,0.000076577446],"about_ca_topic_score_codex":0.00764912,"about_ca_topic_score_gemma":0.017938945,"teacher_disagreement_score":0.021593694,"about_ca_system_score_codex":0.00078058837,"about_ca_system_score_gemma":0.001348499,"threshold_uncertainty_score":0.07223809},"labels":[],"label_agreement":null},{"id":"W6929493724","doi":"10.5061/dryad.kk17v5d/3","title":"Population and Origin Feature ID (RSV) Matrix","year":2019,"lang":"en","type":"other","venue":"Figshare","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Feature (linguistics); Pattern recognition (psychology); Population; Matrix (chemical analysis); Feature extraction; Taxon","score_opus":0.015602226948125,"score_gpt":0.2791029148884267,"score_spread":0.2635006879403017,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929493724","genre_codex":"dataset","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10479188,0.00019329527,0.014094103,0.00032226252,0.00019121062,0.00019021684,0.86933213,0.00423005,0.0066549163],"genre_scores_gemma":[0.15234318,0.000108809545,0.03867029,0.00016820269,0.00004608512,0.0003935324,0.7984902,0.0008142276,0.008965478],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9995233,0.00005350725,0.00003831357,0.00023446708,0.00008128236,0.00006906914],"domain_scores_gemma":[0.9986369,0.00047730154,0.000109793065,0.0002468757,0.0004279109,0.000101244645],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00053823384,0.00059055194,0.0006191128,0.0015548622,0.0006963643,0.00084345246,0.0005848762,0.00039621923,0.05498503],"category_scores_gemma":[0.003493702,0.00019631944,0.0004102331,0.0019622068,0.00029005684,0.00039444625,0.0007059658,0.00070527854,0.012979162],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0021963834,0.0004660934,0.17323928,0.0022886621,0.00050580763,0.0012300067,0.0014220767,0.004659405,0.06022658,0.005697512,0.4730475,0.2750207],"study_design_scores_gemma":[0.0003976176,0.0005484104,0.29451993,0.00031000705,0.00032432767,0.0016836951,0.0018912969,0.017019719,0.0251191,0.008505331,0.6494788,0.00020166389],"about_ca_topic_score_codex":0.011521474,"about_ca_topic_score_gemma":0.022912765,"teacher_disagreement_score":0.94501495,"about_ca_system_score_codex":0.0005224287,"about_ca_system_score_gemma":0.0010782589,"threshold_uncertainty_score":0.18394327},"labels":[],"label_agreement":null},{"id":"W6929904344","doi":"10.5061/dryad.4d12c92","title":"Data from: Consumer-resource interactions along urbanization gradients drive natural selection","year":2018,"lang":"en","type":"dataset","venue":"Data Archiving and Networked Services (DANS)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Urbanization; Natural selection; Habitat; Gall; Predation; Adaptation (eye)","score_opus":0.019807168140969274,"score_gpt":0.278874058596368,"score_spread":0.2590668904553987,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6929904344","genre_codex":"dataset","genre_gemma":"dataset","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"dataset","genre_consensus":"dataset","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00072627375,0.00006139954,0.00007776884,0.00009290596,0.000014602345,0.0000100207235,0.99831486,0.00023391978,0.00046841457],"genre_scores_gemma":[0.0019292618,0.0000718343,0.00038334267,0.00004066212,0.0000051814636,0.00008705266,0.99686426,0.000069386486,0.00054894626],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992299,0.0001191835,0.000108642176,0.0002258524,0.00019207352,0.00012441925],"domain_scores_gemma":[0.99805,0.00066679285,0.00031397436,0.00037525385,0.0003706359,0.00022338472],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010913579,0.001494357,0.0010455338,0.0022967008,0.0006726329,0.0017930219,0.0019813736,0.0014043541,0.043771293],"category_scores_gemma":[0.0060327533,0.00048396163,0.00093180954,0.003863294,0.0004411427,0.0008873534,0.0017572547,0.0014750916,0.031939425],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027377176,0.00006762272,0.012618719,0.0022087332,0.00018753126,0.000114281895,0.00014817312,0.0011810006,0.00073991064,0.001290448,0.97499406,0.0061758263],"study_design_scores_gemma":[0.0005677237,0.000030914696,0.036262393,0.00040097325,0.000083757055,0.0001308824,0.00016276124,0.001022145,0.0009198287,0.0017394061,0.9586253,0.00005394411],"about_ca_topic_score_codex":0.019341163,"about_ca_topic_score_gemma":0.034881875,"teacher_disagreement_score":0.043771293,"about_ca_system_score_codex":0.0011930878,"about_ca_system_score_gemma":0.0017800676,"threshold_uncertainty_score":0.1464296},"labels":[],"label_agreement":null},{"id":"W6930116358","doi":"10.5281/zenodo.10571343","title":"FIGURES 10–12 in Three New Species of Microsphecodes s.str. (Hymenoptera: Halictidae) with an updated key to species of the subgenus","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"York University","funders":"","keywords":"Subgenus; Key (lock); Taxonomy (biology); Holotype; Taxonomic key","score_opus":0.02408616309316898,"score_gpt":0.2346255801516336,"score_spread":0.21053941705846463,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930116358","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.056261204,0.008479738,0.018269489,0.0017362915,0.0047872565,0.00093017594,0.036293488,0.0027003721,0.870542],"genre_scores_gemma":[0.18695118,0.008685099,0.046476632,0.0015853051,0.001199177,0.0007012035,0.044993266,0.00095995195,0.7084483],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999025,0.000012156444,0.000008504917,0.000032395397,0.00002874804,0.000015758515],"domain_scores_gemma":[0.99992025,0.000016660915,0.000018697443,0.000011699232,0.000015374173,0.000017332874],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009130504,0.0005172707,0.00017239411,0.0014705866,0.00061762374,0.00038759268,0.00054367975,0.00047403006,0.1588635],"category_scores_gemma":[0.00019578816,0.00019191214,0.00028135217,0.0013101796,0.0005312405,0.0009441543,0.00066340674,0.0010084257,0.04973156],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003570088,0.000082776554,0.0060580526,0.0008216478,0.00003065196,0.00094001717,0.00095900625,0.0003728974,0.019151367,0.008256688,0.46859315,0.49437672],"study_design_scores_gemma":[0.000014075292,0.000030587067,0.021775682,0.000068369525,0.00001144515,0.0012228691,0.00018877666,0.00007476847,0.0010200072,0.00074647454,0.9748366,0.00001039516],"about_ca_topic_score_codex":0.0029838968,"about_ca_topic_score_gemma":0.01193503,"teacher_disagreement_score":0.1588635,"about_ca_system_score_codex":0.0003973485,"about_ca_system_score_gemma":0.00031040565,"threshold_uncertainty_score":0.53145134},"labels":[],"label_agreement":null},{"id":"W6930236530","doi":"10.5281/zenodo.10932950","title":"Mixtures of legacy and replacement perfluorosulphonic acids (PFSAs) demonstrate ratio-, concentration- and endpoint-dependent synergistic interactions","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Ternary operation; Additive function; Cell culture; Viability assay; Ternary complex","score_opus":0.015999565852694634,"score_gpt":0.25279532244880465,"score_spread":0.23679575659611002,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930236530","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9891794,0.0028942865,0.0036875398,0.00007929577,0.00003772759,0.00005806783,0.00038023497,0.00008041157,0.003603099],"genre_scores_gemma":[0.99298674,0.0011692974,0.003351007,0.000049264436,0.000010534696,0.000031221072,0.00031979376,0.000015284306,0.0020668576],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.99938536,0.00009033929,0.000048853424,0.00011596587,0.00028178858,0.00007767336],"domain_scores_gemma":[0.9997912,0.000052398063,0.000054379467,0.00001942469,0.00006049281,0.000022065027],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00031469797,0.00044955965,0.00033360333,0.00040410072,0.00016398379,0.00036542973,0.00019889124,0.00034321737,0.0009677058],"category_scores_gemma":[0.00033775024,0.00022403261,0.00044474693,0.00027171802,0.00023576934,0.00033680766,0.00044815897,0.0003479694,0.00030811707],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012417677,0.00002572339,0.001078594,0.000053726795,0.000018428931,0.000040194675,0.000023064762,0.00014695311,0.9948612,0.000040221785,0.000041357674,0.0035464254],"study_design_scores_gemma":[0.0000047987337,0.00092172954,0.0072311237,0.0000063745256,0.000038785078,0.00013746663,0.000055509292,0.00064649415,0.9895509,0.000038201586,0.0013607042,0.000007887004],"about_ca_topic_score_codex":0.0021019643,"about_ca_topic_score_gemma":0.0047614435,"teacher_disagreement_score":0.0021019643,"about_ca_system_score_codex":0.0003688232,"about_ca_system_score_gemma":0.0003355676,"threshold_uncertainty_score":0.004179418},"labels":[],"label_agreement":null},{"id":"W6930383812","doi":"10.5281/zenodo.12939584","title":"canadian criminal law","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Criminal law; Criminal justice; Criminal procedure; Legislation; Public law","score_opus":0.023608383722213758,"score_gpt":0.24732926567372154,"score_spread":0.2237208819515078,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930383812","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009530476,0.0020869863,0.00025522552,0.013736423,0.0011859777,0.000091462505,0.0020920776,0.00012370253,0.97947514],"genre_scores_gemma":[0.0050902865,0.00073067157,0.00017633382,0.003783754,0.00013521002,0.000051205345,0.00039307648,0.00005743746,0.98958206],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99680895,0.00018621526,0.0000772932,0.00042231195,0.0015677854,0.00093743246],"domain_scores_gemma":[0.99746007,0.00035542843,0.000059578775,0.0001956535,0.0014847099,0.00044460132],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0012838856,0.0012975507,0.0008613687,0.0037404152,0.0201809,0.009499908,0.0026963188,0.011521811,0.28700858],"category_scores_gemma":[0.006130833,0.00094797753,0.0009740698,0.003099252,0.0026176076,0.0023676788,0.0027783702,0.008615169,0.058536172],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000011087106,0.000023175622,0.00019174504,0.00003170718,0.0000041870544,0.0000812324,0.00016809192,0.000087879,0.000042984993,0.084700786,0.8990512,0.015605913],"study_design_scores_gemma":[0.000007877778,0.0000037665357,0.0005520714,0.00007098864,0.000005834459,0.000034834844,0.00016789883,0.00011062691,0.00005815602,0.0048338403,0.99414,0.000014196048],"about_ca_topic_score_codex":0.87601596,"about_ca_topic_score_gemma":0.95503604,"teacher_disagreement_score":0.87601596,"about_ca_system_score_codex":0.033324808,"about_ca_system_score_gemma":0.065499455,"threshold_uncertainty_score":0.9601394},"labels":[],"label_agreement":null},{"id":"W6930551623","doi":"10.5281/zenodo.12770828","title":"Supranail Canada Reviews &amp; Ingredients – Supranail Experiences Official Price, Buy","year":2024,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Product (mathematics); Quality (philosophy); Health care; Pride; Packaging and labeling; Product line","score_opus":0.029613859208711832,"score_gpt":0.25841560320746765,"score_spread":0.2288017439987558,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930551623","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0006089439,0.018539818,0.0009993825,0.0050988025,0.0043081073,0.00039891765,0.008335915,0.0030440984,0.9586661],"genre_scores_gemma":[0.0029579322,0.01124645,0.0012874601,0.0045978953,0.00086281763,0.00011841656,0.0032539503,0.0014424749,0.9742327],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9985972,0.000061814884,0.00003688711,0.00010514035,0.0010789251,0.00012002802],"domain_scores_gemma":[0.99562246,0.00031879332,0.00013188519,0.0001707861,0.0028401846,0.0009158986],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00088529143,0.00074036064,0.00055082445,0.0024255302,0.0012281606,0.004405037,0.0009878643,0.001921857,0.6425305],"category_scores_gemma":[0.0041757133,0.00042936252,0.0004904311,0.0022589539,0.0005847109,0.0023866585,0.0013005103,0.0015754716,0.47261328],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022456461,0.000017265884,0.000025392228,0.00036461646,0.0000025272823,0.000024463801,0.000032297427,0.000011755314,0.00095420075,0.0009798866,0.9547553,0.042809803],"study_design_scores_gemma":[0.0000046403457,0.000006256636,0.000079098034,0.00006085839,0.0000017082992,0.000020979132,0.000018000106,0.0000057858465,0.00016223009,0.00008181203,0.99955565,0.0000029288683],"about_ca_topic_score_codex":0.06985539,"about_ca_topic_score_gemma":0.26148212,"teacher_disagreement_score":0.3574695,"about_ca_system_score_codex":0.0046530976,"about_ca_system_score_gemma":0.008479208,"threshold_uncertainty_score":0.50988686},"labels":[],"label_agreement":null},{"id":"W6930556437","doi":"10.5281/zenodo.14130486","title":"PM_065367_E_Cuenca","year":2011,"lang":"en","type":"other","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Verisimilitude; Thematic map; Period (music); Quarter (Canadian coin)","score_opus":0.03207906334232699,"score_gpt":0.23939844733907667,"score_spread":0.20731938399674968,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6930556437","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00028961722,0.00024572248,0.00057569525,0.0005916572,0.0010491686,0.00015341004,0.13328163,0.0066989576,0.85711426],"genre_scores_gemma":[0.002300891,0.00040155184,0.0008039555,0.00027375808,0.00029097407,0.0001597368,0.03782485,0.004908622,0.9530357],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99970835,0.000025446685,0.000016742255,0.00007185872,0.00011205269,0.00006559673],"domain_scores_gemma":[0.9979686,0.00024757168,0.00007646641,0.00029114043,0.0010124634,0.00040378424],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0003723765,0.00096090976,0.00089198735,0.0018994967,0.0016081142,0.0055242013,0.0016794014,0.0012106126,0.9338317],"category_scores_gemma":[0.0033541769,0.00053603516,0.00045462372,0.004801978,0.00041535258,0.0019409114,0.0017481294,0.0009822513,0.8716496],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000028482822,0.000008835557,0.00006555996,0.000077936755,9.670412e-7,0.000016119506,0.000022134263,0.000016406722,0.000069823756,0.0002494985,0.9879615,0.011482662],"study_design_scores_gemma":[0.000018235249,0.000003840589,0.00056334696,0.00005081134,0.0000016052445,0.000019491663,0.00006458308,0.000025491596,0.00015597531,0.00011821023,0.9989717,0.0000066958323],"about_ca_topic_score_codex":0.048241913,"about_ca_topic_score_gemma":0.041596163,"teacher_disagreement_score":0.06616831,"about_ca_system_score_codex":0.0018137618,"about_ca_system_score_gemma":0.001798143,"threshold_uncertainty_score":0.09592223},"labels":[],"label_agreement":null},{"id":"W6931214767","doi":"10.5281/zenodo.4175240","title":"FLQ: la traque (2020) Film ▶ HD !Complet En Francais ~ Streaming Vf Entier 4k. wny","year":2020,"lang":"fr","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Oscillograph; Fusible alloy; Field (mathematics)","score_opus":0.021406594959964425,"score_gpt":0.23777862389135757,"score_spread":0.21637202893139315,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931214767","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0009177015,0.00057346886,0.0014670397,0.0017702264,0.00245577,0.00032903432,0.02759683,0.008743343,0.9561467],"genre_scores_gemma":[0.0041708928,0.0005519339,0.001260516,0.000590719,0.0002859245,0.00012999958,0.012805928,0.0041758977,0.9760283],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996257,0.000022538112,0.000010980617,0.000046588095,0.00018918105,0.0001050003],"domain_scores_gemma":[0.99889165,0.00005958047,0.000022220154,0.00009998293,0.00062946056,0.00029711841],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00058879703,0.0008021929,0.00034776394,0.0011453906,0.0022692666,0.0050354945,0.0010055614,0.0010878863,0.82525516],"category_scores_gemma":[0.001644877,0.0005339918,0.00052342983,0.0012375772,0.00039680814,0.0036004079,0.0020955908,0.0018380859,0.5870071],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022191209,0.000006392805,0.000045337463,0.000048433874,0.0000010583987,0.0000199621,0.000058645357,0.000017442531,0.00035283234,0.0006308672,0.9872958,0.011501209],"study_design_scores_gemma":[0.000008046843,0.000006829442,0.0004719239,0.00005004403,0.000001529333,0.000030177804,0.000115041614,0.000037309845,0.00024507268,0.00011286181,0.99891305,0.000008258072],"about_ca_topic_score_codex":0.06250227,"about_ca_topic_score_gemma":0.13290715,"teacher_disagreement_score":0.17474484,"about_ca_system_score_codex":0.0022830942,"about_ca_system_score_gemma":0.0016695784,"threshold_uncertainty_score":0.24925226},"labels":[],"label_agreement":null},{"id":"W6931829231","doi":"10.5281/zenodo.7468594","title":"Purification of MFSD10 (Tetrana) from Expi293FTM Cells","year":2022,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Discovery Centre","funders":"European Commission","keywords":"Solubilization; Transporter; Transfection; Proteolysis; Cell culture; Recombinant DNA","score_opus":0.023917225366722392,"score_gpt":0.22763519044971672,"score_spread":0.20371796508299433,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6931829231","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.34458068,0.0167995,0.40164635,0.0029648857,0.004170049,0.005069002,0.15877426,0.022485377,0.04350999],"genre_scores_gemma":[0.26154503,0.00839389,0.24484058,0.0015495223,0.0004858276,0.0047868323,0.37809408,0.005841953,0.0944623],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9991689,0.0000786061,0.000109314184,0.00023392482,0.00027205507,0.00013719793],"domain_scores_gemma":[0.9995789,0.000089305286,0.00003300941,0.00011411672,0.0001098939,0.00007487384],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0010048216,0.0012263563,0.0017345324,0.0009968536,0.00097644667,0.0012927534,0.0018551315,0.0013120157,0.010361857],"category_scores_gemma":[0.0010887427,0.00081116956,0.00101906,0.0011928327,0.0005323848,0.00071814476,0.0010315414,0.0034382362,0.023174964],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013512453,0.00007593719,0.00026031357,0.00042245848,0.000020404974,0.00015010363,0.00012757584,0.00015604334,0.9839627,0.0007597729,0.006022551,0.007907014],"study_design_scores_gemma":[0.0001372718,0.00019483594,0.0031412481,0.000115560935,0.000051820043,0.0008323769,0.00008877891,0.0026449075,0.7904132,0.00071240065,0.20159335,0.00007421095],"about_ca_topic_score_codex":0.0018593143,"about_ca_topic_score_gemma":0.0025782112,"teacher_disagreement_score":0.010361857,"about_ca_system_score_codex":0.0010179557,"about_ca_system_score_gemma":0.00073109113,"threshold_uncertainty_score":0.034663856},"labels":[],"label_agreement":null},{"id":"W6957633440","doi":"10.60692/9vbtm-m3q41","title":"Relationships between the discrete Riemann-Liouville and Liouville-Caputo fractional differences and their associated convexity results","year":2022,"lang":"en","type":"article","venue":"Greater South Information System","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Victoria","funders":"","keywords":"Nabla symbol; Convexity; Type (biology); Fractional calculus; Delta","score_opus":0.044953752138994676,"score_gpt":0.21566499465682462,"score_spread":0.17071124251782993,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6957633440","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.100429624,0.002353393,0.8458564,0.0018238601,0.0003024861,0.00007151807,0.00021015476,0.00008782831,0.04886475],"genre_scores_gemma":[0.8418771,0.001970792,0.14130576,0.00056229735,0.00039333603,0.0001525658,0.00016598066,0.00010908774,0.013463115],"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","domain_scores_codex":[0.9990452,0.00028613253,0.00007327392,0.00017782528,0.00030471897,0.00011284069],"domain_scores_gemma":[0.99583924,0.002391482,0.00046213996,0.00030422353,0.00073277083,0.00027010142],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0025629702,0.00065540115,0.00046122406,0.0021927403,0.0009089537,0.0023471664,0.0009036366,0.00084983214,0.002821864],"category_scores_gemma":[0.007909548,0.00023566416,0.0008958981,0.0010356732,0.003360925,0.00395936,0.0017005088,0.0027952632,0.00032925283],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000014701243,0.000009164636,0.00042202076,0.00003388512,0.0000070356614,0.00005967505,0.000107485284,0.00494934,0.001338201,0.9874286,0.00026843543,0.0053614564],"study_design_scores_gemma":[0.0000072672096,0.00003355738,0.0011289218,0.000028907698,0.000011736432,0.0002586503,0.0001443627,0.06396806,0.0020238173,0.92597324,0.006386814,0.000034700883],"about_ca_topic_score_codex":0.0013754829,"about_ca_topic_score_gemma":0.00088932767,"teacher_disagreement_score":0.002821864,"about_ca_system_score_codex":0.002225625,"about_ca_system_score_gemma":0.00097145437,"threshold_uncertainty_score":0.01614809},"labels":[],"label_agreement":null},{"id":"W6958401659","doi":"10.6084/m9.figshare.26756161.v1","title":"Additional file 2 of Utilization of integrated community-based case management of childhood illness and associated factors in Ethiopia: a systematic review and meta-analysis","year":2024,"lang":"en","type":"article","venue":"Figshare","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Case management; Scale (ratio); Quality (philosophy); MEDLINE; Data collection; Primary care","score_opus":0.06349664531621974,"score_gpt":0.29622339222828264,"score_spread":0.2327267469120629,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6958401659","genre_codex":"dataset","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0010546908,0.0012302044,0.00053034426,0.00030575547,0.000081475904,0.0012202607,0.99461293,0.00019434703,0.0007700684],"genre_scores_gemma":[0.090826996,0.0081186015,0.026127372,0.003811275,0.0007039974,0.113818616,0.72624856,0.0009772079,0.02936734],"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","domain_scores_codex":[0.99706775,0.00073153374,0.0011116837,0.00043269416,0.00041816846,0.0002382284],"domain_scores_gemma":[0.95349354,0.035284884,0.0066508534,0.0012778116,0.0028552187,0.00043768223],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0053501637,0.0013582071,0.00366681,0.0054353764,0.0005916931,0.0018082295,0.0015696946,0.0012405987,0.60964906],"category_scores_gemma":[0.05753644,0.0008563322,0.005579322,0.008958167,0.0003049056,0.0026382855,0.0012402968,0.000934385,0.013374999],"study_design_candidate":"meta_analysis","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.004011368,0.000113844704,0.0074380394,0.6912827,0.008978845,0.00022269292,0.00028567642,0.0009402675,0.00043455535,0.0019396996,0.26567632,0.01867595],"study_design_scores_gemma":[0.07753121,0.0020113944,0.13047096,0.2568445,0.07386086,0.0015589949,0.0013163023,0.005038195,0.0018913602,0.014591223,0.43425995,0.00062513474],"about_ca_topic_score_codex":0.006468094,"about_ca_topic_score_gemma":0.017359136,"teacher_disagreement_score":0.60964906,"about_ca_system_score_codex":0.0016638656,"about_ca_system_score_gemma":0.0035574432,"threshold_uncertainty_score":0.5567882},"labels":[],"label_agreement":null},{"id":"W6996519037","doi":"","title":"The Roles of Presenilin and FKBP14 in Drosophila Development and Notch Signalling","year":2008,"lang":"en","type":"dissertation","venue":"TSpace","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Presenilin; Nicastrin; Notch signaling pathway; Null allele; Mutant; Enhancer; Transmembrane protein; Gene","score_opus":0.01404895499903031,"score_gpt":0.2902059191250278,"score_spread":0.2761569641259975,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6996519037","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9403462,0.04155765,0.0021512287,0.0011431794,0.00013093553,0.000044617023,0.00033295265,0.00007329137,0.014219975],"genre_scores_gemma":[0.9634211,0.012289124,0.0015654681,0.00018221297,0.00003327234,0.00002692123,0.00046594767,0.00001152397,0.022004332],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9999317,0.0000064966052,0.000003715327,0.000012914992,0.000025270945,0.000019909532],"domain_scores_gemma":[0.9999597,0.0000035034707,0.000009496203,0.0000029357473,0.000008266527,0.000016040556],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008723282,0.00036502408,0.00013017685,0.00025291173,0.00031591905,0.000390543,0.00025129362,0.0003261785,0.0012181852],"category_scores_gemma":[0.000065526845,0.00019150086,0.00011282115,0.000084821964,0.00024160776,0.00023745181,0.0002521788,0.00029347243,0.00044873758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00050654216,0.000039807866,0.0017086588,0.00012477583,0.000017668946,0.00037699775,0.000044924225,0.00032510306,0.97499317,0.0016259603,0.0008197812,0.019416567],"study_design_scores_gemma":[0.00015656321,0.00045859953,0.14141577,0.000083570645,0.00010560633,0.0019653304,0.00030520576,0.0052776556,0.7898876,0.0015715493,0.05873774,0.000034733857],"about_ca_topic_score_codex":0.0033475857,"about_ca_topic_score_gemma":0.008374523,"teacher_disagreement_score":0.0033475857,"about_ca_system_score_codex":0.0010961733,"about_ca_system_score_gemma":0.00039074355,"threshold_uncertainty_score":0.007953346},"labels":[],"label_agreement":null},{"id":"W7015120669","doi":"","title":"The Role of FKBP5 in Influenza Virus Infection","year":2010,"lang":"en","type":"dissertation","venue":"Library and Archives Canada (Government of Canada)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"FKBP5; Cytokine; Immune system; Influenza A virus; Interferon; Cytokine storm; RIG-I; Glucocorticoid; Orthomyxoviridae","score_opus":0.0019513637153295857,"score_gpt":0.16366476690719706,"score_spread":0.16171340319186747,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7015120669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.72279966,0.22650236,0.00757291,0.0022048955,0.00055677776,0.00012040164,0.0011241438,0.00018016482,0.038938668],"genre_scores_gemma":[0.9562526,0.024823036,0.0015556458,0.00017301511,0.000045403256,0.000029695611,0.0004484122,0.000008498124,0.016663732],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99993265,0.000008739697,0.0000034341208,0.000012171312,0.000013787576,0.000029168488],"domain_scores_gemma":[0.99996567,0.0000036768417,0.0000064895685,0.0000021446008,0.000010302973,0.00001183077],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012940494,0.00023845554,0.0001838545,0.00025028936,0.00042109416,0.00033870226,0.000153616,0.00033993006,0.0013687928],"category_scores_gemma":[0.00009195302,0.00010612241,0.00020539647,0.00014606341,0.00023398986,0.00015877045,0.0002037731,0.00036643253,0.00048920594],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006784219,0.000055698,0.0016654658,0.00040100576,0.000025050002,0.00051860505,0.00015323928,0.00032720616,0.94456816,0.0023838195,0.0017361529,0.047487203],"study_design_scores_gemma":[0.00005314703,0.00075701403,0.21027529,0.00033356203,0.00014316509,0.0017816888,0.0004602517,0.0016497377,0.69853204,0.0016946684,0.08426175,0.000057632704],"about_ca_topic_score_codex":0.009167219,"about_ca_topic_score_gemma":0.00827456,"teacher_disagreement_score":0.009167219,"about_ca_system_score_codex":0.0012080697,"about_ca_system_score_gemma":0.0005242257,"threshold_uncertainty_score":0.018227756},"labels":[],"label_agreement":null},{"id":"W7034919481","doi":"","title":"Will Canada head back to the polls this fall?","year":2022,"lang":"en","type":"other","venue":"Bulletin of Miscellaneous Information (Royal Gardens Kew)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Head (geology); Government (linguistics)","score_opus":0.0050080924258797755,"score_gpt":0.1835413846660472,"score_spread":0.17853329224016742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7034919481","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00045465448,0.000839043,0.00023539344,0.016933633,0.0121990545,0.0001496891,0.005295211,0.0011220796,0.9627713],"genre_scores_gemma":[0.00068606634,0.00022643189,0.00007037529,0.0021951701,0.00022665117,0.000022125188,0.0005338643,0.00018374491,0.9958555],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9993437,0.00003064257,0.000014417435,0.00006299102,0.00029134174,0.0002568354],"domain_scores_gemma":[0.9974004,0.000113040944,0.00004426553,0.000064296604,0.001126307,0.0012516937],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00076512014,0.0006759327,0.00074490695,0.0015607147,0.007120653,0.006075054,0.000980669,0.0031504505,0.7720226],"category_scores_gemma":[0.0037331758,0.00051527866,0.00042477364,0.00193203,0.0007236328,0.0018590187,0.0018789145,0.0024641391,0.61372685],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000005541829,0.000003159272,0.00004577018,0.000006229396,2.8414553e-7,0.00000981127,0.000012016102,0.0000028356744,0.000014839065,0.00029414278,0.99673694,0.0028683934],"study_design_scores_gemma":[0.0000031510401,0.000001996618,0.0002793566,0.000019912035,6.4482384e-7,0.0000063934444,0.00016619964,0.0000072263874,0.000021011232,0.00007770417,0.999411,0.0000054286697],"about_ca_topic_score_codex":0.40613303,"about_ca_topic_score_gemma":0.77723837,"teacher_disagreement_score":0.7720226,"about_ca_system_score_codex":0.0052473247,"about_ca_system_score_gemma":0.009020625,"threshold_uncertainty_score":0.80753815},"labels":[],"label_agreement":null},{"id":"W7099727378","doi":"","title":"1 Executive Summary","year":2003,"lang":"en","type":"article","venue":"","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Executive summary; Stock (firearms); Population; Stock assessment; West coast","score_opus":0.010613526868686655,"score_gpt":0.2419779577637679,"score_spread":0.23136443089508124,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7099727378","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.001187413,0.011208881,0.0023641614,0.028792711,0.032798316,0.0020456717,0.060384247,0.0012758797,0.8599428],"genre_scores_gemma":[0.0040950356,0.008591519,0.0011982613,0.0075624506,0.0037269315,0.00092228665,0.026297506,0.00030274002,0.94730324],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.9979786,0.00025261656,0.00017074058,0.00027639602,0.0010859681,0.0002356611],"domain_scores_gemma":[0.9910682,0.00095448387,0.0005001345,0.00048757147,0.006288723,0.0007010036],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0029573573,0.0008626739,0.0006969403,0.0033051954,0.00092528004,0.004597238,0.0019972525,0.0024274106,0.41815436],"category_scores_gemma":[0.012197247,0.00036980957,0.00054221804,0.0033418045,0.00026696664,0.0024390216,0.0012506477,0.0016360048,0.34267095],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000023967566,0.000010830271,0.00013213766,0.00020003137,0.000002262892,0.000018631386,0.000009779279,0.00006543972,0.000059948437,0.001683273,0.9535055,0.044288117],"study_design_scores_gemma":[0.000004471494,0.000009819268,0.00047351397,0.00018432255,0.0000026684245,0.000011196217,0.000019252679,0.000024711051,0.000037407954,0.00028936705,0.9989403,0.0000029925263],"about_ca_topic_score_codex":0.008161883,"about_ca_topic_score_gemma":0.0065752626,"teacher_disagreement_score":0.58184564,"about_ca_system_score_codex":0.0015975183,"about_ca_system_score_gemma":0.006632534,"threshold_uncertainty_score":0.8299322},"labels":[],"label_agreement":null},{"id":"W7145200913","doi":"","title":"Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue","year":2020,"lang":"en","type":"article","venue":"Institutional Repositories DataBase (IRDB)","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"McMaster University","keywords":"Respiratory epithelium; Receptor; Gene expression; Gene expression profiling; Epithelium; Cell; Transcriptome; Cell culture; Microarray analysis techniques; Lung","score_opus":0.015377757724004234,"score_gpt":0.2707966997438301,"score_spread":0.25541894201982585,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7145200913","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9737594,0.0024288513,0.0057722745,0.00015029384,0.000031038322,0.000041646785,0.016377041,0.000121847545,0.0013176469],"genre_scores_gemma":[0.94150233,0.0022575825,0.014195022,0.00040125023,0.000032940297,0.00021172204,0.037422996,0.00009202766,0.0038841206],"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","domain_scores_codex":[0.9996536,0.000028979839,0.000017418286,0.00015795777,0.000086053544,0.00005602202],"domain_scores_gemma":[0.99992144,0.000019486224,0.000015436115,0.000010010236,0.00002102794,0.000012726765],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00020859769,0.00024948263,0.0004069845,0.00045650257,0.0002311227,0.00038406922,0.0001386122,0.00034157385,0.001298695],"category_scores_gemma":[0.00021582222,0.00017584213,0.0004328561,0.000494557,0.00015401185,0.00011525988,0.00024616218,0.00032299582,0.00063060696],"study_design_candidate":"observational","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002424801,0.00001599372,0.005365975,0.0001329774,0.000039922903,0.00009277185,0.00008521241,0.0001206705,0.9911642,0.000031403608,0.0002084353,0.0024999622],"study_design_scores_gemma":[0.00003765821,0.0006250922,0.45111656,0.00004486329,0.0002367236,0.0020098244,0.0005360758,0.0045948816,0.52922165,0.00019166339,0.011337891,0.000047091668],"about_ca_topic_score_codex":0.001170515,"about_ca_topic_score_gemma":0.002002524,"teacher_disagreement_score":0.001298695,"about_ca_system_score_codex":0.00014970388,"about_ca_system_score_gemma":0.00017442704,"threshold_uncertainty_score":0.0043445826},"labels":[],"label_agreement":null},{"id":"W7154596000","doi":"10.2310/6620.2008.00007dd","title":"An Update on Topical Calcineurin Inhibitors","year":2008,"lang":"en","type":"article","venue":"Dermatitis","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"","score_opus":0.012443702350622693,"score_gpt":0.2503142542879046,"score_spread":0.2378705519372819,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7154596000","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0017126672,0.97200274,0.0016628685,0.0063177766,0.008904554,0.000029094159,0.00015090303,0.000099833414,0.009119602],"genre_scores_gemma":[0.008029323,0.9473637,0.0031774174,0.011530232,0.012972068,0.00007217823,0.00042328532,0.00003216391,0.016399639],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9996172,0.00006532912,0.000080073456,0.00003501611,0.000172064,0.000030253963],"domain_scores_gemma":[0.99914694,0.00045696678,0.00009689568,0.000031168118,0.000206836,0.00006109665],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006593984,0.00068207434,0.0014710426,0.0015799933,0.00032171767,0.00092519703,0.00062623323,0.0012632933,0.0042490633],"category_scores_gemma":[0.0012311443,0.0002435315,0.00054015755,0.0011862472,0.00026189076,0.0013773206,0.00035190128,0.0018911716,0.0022813862],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00029629955,0.000103009275,0.0005441871,0.0042213267,0.00012825361,0.0014779221,0.000035343313,0.00018019925,0.0037668776,0.0008096684,0.1603928,0.82804406],"study_design_scores_gemma":[0.0000806576,0.0002074702,0.0014181761,0.00093355234,0.00025429745,0.0046111504,0.00003529909,0.0001615125,0.0009825738,0.00048505416,0.9908132,0.00001699059],"about_ca_topic_score_codex":0.0008122761,"about_ca_topic_score_gemma":0.0041037435,"teacher_disagreement_score":0.0042490633,"about_ca_system_score_codex":0.00044813956,"about_ca_system_score_gemma":0.000492683,"threshold_uncertainty_score":0.014214516},"labels":[],"label_agreement":null},{"id":"W76562646","doi":"10.1096/fasebj.24.1_supplement.lb594","title":"Differential calcineurin/NFATc1‐c3 signaling in the regulation of the skeletal muscle fiber phenotype","year":2010,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"NFAT; Gene isoform; Biology; Phenotype; Transcription factor; Skeletal muscle; Calcineurin; Cell biology; Gene expression; Transgene; Regulation of gene expression; Gene; Genetics; Internal medicine; Endocrinology; Transplantation; Medicine","score_opus":0.01050108058747752,"score_gpt":0.2377254291902551,"score_spread":0.2272243486027776,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W76562646","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99641514,0.0009715474,0.0015797007,0.00006352738,0.000010320794,0.00001350783,0.00017083406,0.000029708457,0.00074573676],"genre_scores_gemma":[0.99701345,0.00036617237,0.0009862463,0.000024840281,0.0000031343627,0.000019540716,0.00015225967,0.000011962054,0.0014224622],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997844,0.000025449472,0.000017534572,0.000058139864,0.00006410009,0.000050356517],"domain_scores_gemma":[0.9998394,0.000022500662,0.00003733843,0.000018494002,0.000021285126,0.00006088351],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00027715415,0.00041644147,0.000183071,0.00030332428,0.00026683277,0.00030527878,0.00026054317,0.00033182418,0.0011676963],"category_scores_gemma":[0.00013541784,0.00015449767,0.00025119062,0.0001726685,0.00051072385,0.00028898584,0.000219295,0.00048236438,0.00017143958],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007654261,0.0000082044535,0.00040846012,0.0000115262455,0.0000016457866,0.000021997186,0.000008336302,0.000019378416,0.9990012,0.000037749014,0.0000043895175,0.0004005344],"study_design_scores_gemma":[0.000032958054,0.00022305928,0.058491282,0.000011093421,0.000027161277,0.0004978127,0.00006996656,0.0012366404,0.9385288,0.00014947668,0.00072382257,0.000007883972],"about_ca_topic_score_codex":0.0023304836,"about_ca_topic_score_gemma":0.0058720624,"teacher_disagreement_score":0.0023304836,"about_ca_system_score_codex":0.00056851114,"about_ca_system_score_gemma":0.0004902509,"threshold_uncertainty_score":0.004633844},"labels":[],"label_agreement":null},{"id":"W802095953","doi":"10.1139/y06-004","title":"Phosphorylation and dephosphorylation of human myristoyltransferase type 1This paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference.","year":2006,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Saskatchewan Cancer Agency","funders":"","keywords":"Phosphorylation; FYN; Autophosphorylation; Biochemistry; Biology; Dephosphorylation; Protein tyrosine phosphatase; Kinase; Receptor tyrosine kinase; Phosphatase; Tyrosine; Cell biology; Proto-oncogene tyrosine-protein kinase Src; Protein kinase A","score_opus":0.01747443936829218,"score_gpt":0.28576183347505296,"score_spread":0.2682873941067608,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W802095953","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.00075042486,0.9952938,0.00028417134,0.00020496592,0.00029590627,0.000009241468,0.000027793485,0.000015642889,0.0031180473],"genre_scores_gemma":[0.0031652397,0.99132854,0.00036674342,0.00014242098,0.0001618448,0.000010947713,0.00009250265,0.0000027754008,0.004728964],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9999169,0.000008723063,0.000009293156,0.000021716849,0.000031208325,0.0000121230905],"domain_scores_gemma":[0.9999385,0.000012198145,0.000013475693,0.0000025013683,0.000020944439,0.0000124054895],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00024086141,0.000754863,0.00077662664,0.0010005239,0.00018245532,0.0004746563,0.0004613406,0.00064728135,0.002953746],"category_scores_gemma":[0.00019197784,0.00017836856,0.00021139621,0.000991026,0.00020077622,0.00073222205,0.00033665117,0.0006000132,0.0037833597],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011979608,0.000063557476,0.00022440718,0.006027268,0.000034239958,0.00032792744,0.00003353469,0.00017502952,0.01869133,0.0017419119,0.016624896,0.95593613],"study_design_scores_gemma":[0.000018816725,0.00012068844,0.0014859634,0.00055339467,0.000040620336,0.0017624052,0.000030828847,0.00006363814,0.0077509484,0.000599852,0.9875607,0.0000121031735],"about_ca_topic_score_codex":0.00059778785,"about_ca_topic_score_gemma":0.0011629825,"teacher_disagreement_score":0.002953746,"about_ca_system_score_codex":0.0004482714,"about_ca_system_score_gemma":0.00051132246,"threshold_uncertainty_score":0.009881258},"labels":[],"label_agreement":null},{"id":"W876019026","doi":"","title":"Biomechanical Insult Initiates a Novel Molecular Switch of the Adapter Protein PEA15 to Promote Matrix Remodeling and Apoptosis","year":2015,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Adapter (computing); Cell biology; Signal transducing adaptor protein; Apoptosis; Insult; Chemistry; Biology; Neuroscience; Genetics; Signal transduction; Engineering; Political science","score_opus":0.05469332205074735,"score_gpt":0.3368721255014378,"score_spread":0.28217880345069046,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W876019026","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98730683,0.0020516287,0.0062199654,0.00023929204,0.00013157983,0.00005701915,0.00021610688,0.00012199426,0.0036555408],"genre_scores_gemma":[0.9944529,0.0003673667,0.002009345,0.00012711204,0.000017461087,0.000051957697,0.00021571861,0.000015582895,0.0027425503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9997559,0.000026499252,0.000012758974,0.00005072312,0.0000536317,0.00010046071],"domain_scores_gemma":[0.9998306,0.000021955024,0.00003936516,0.000028004897,0.000026157011,0.000053993877],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00022934483,0.0003953175,0.00035595064,0.00029592976,0.00037466487,0.00044908977,0.0002932442,0.0005364083,0.0031277777],"category_scores_gemma":[0.00023955826,0.00023243448,0.0006389374,0.00011546746,0.00034555534,0.0005443129,0.0005838998,0.00072423543,0.00052926375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017771541,0.000031949065,0.00044094268,0.00002944768,0.000007891553,0.00029881776,0.000026398619,0.00004387783,0.9968581,0.00082573097,0.000088383276,0.0011709178],"study_design_scores_gemma":[0.00005038434,0.00046132322,0.035251718,0.000023529152,0.000017143815,0.0008371827,0.00018217719,0.0010663848,0.9582393,0.0009585321,0.0028981331,0.000014132369],"about_ca_topic_score_codex":0.00029248252,"about_ca_topic_score_gemma":0.0006879121,"teacher_disagreement_score":0.0031277777,"about_ca_system_score_codex":0.0005282409,"about_ca_system_score_gemma":0.00030111198,"threshold_uncertainty_score":0.010463476},"labels":[],"label_agreement":null},{"id":"W99737864","doi":"10.1074/jbc.m114.602763","title":"Sirtuin 1 Is a Negative Regulator of Parathyroid Hormone Stimulation of Matrix Metalloproteinase 13 Expression in Osteoblastic Cells","year":2015,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Health Canada","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Parathyroid hormone; Matrix metalloproteinase; Regulator; Stimulation; Sirtuin; Internal medicine; Endocrinology; Chemistry; Sirtuin 1; Matrix metalloproteinase 9; Hormone; Cell biology; Biology; Downregulation and upregulation; Medicine; Enzyme; Calcium; Gene; Biochemistry","score_opus":0.02562783521434196,"score_gpt":0.2751364938775647,"score_spread":0.24950865866322278,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W99737864","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"metacan-v3-hybrid-931329e0061c","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8369081,0.10289741,0.030213501,0.0020955668,0.0014430585,0.00019821865,0.005366027,0.0022597904,0.018618345],"genre_scores_gemma":[0.96841687,0.01307842,0.005196653,0.00041179164,0.00012399687,0.00009111125,0.0027802433,0.00008902485,0.009811945],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99974376,0.00003402332,0.000018413428,0.000059320017,0.00009859632,0.000045821558],"domain_scores_gemma":[0.99987006,0.00001151219,0.000043895558,0.000012550049,0.000032211046,0.000029844037],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001751719,0.00041229688,0.00043565486,0.00031370585,0.00037590883,0.0003061873,0.0003003299,0.0003007485,0.002461337],"category_scores_gemma":[0.00018867364,0.00020711744,0.00058579835,0.00031377436,0.00027381536,0.00015011869,0.00030173935,0.0005881924,0.00091203046],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031809448,0.000043406122,0.0014592573,0.00036139291,0.0000547955,0.0002908881,0.0000570836,0.00008390841,0.98347974,0.00045246078,0.0013962821,0.012002763],"study_design_scores_gemma":[0.00017342932,0.0005000648,0.064625114,0.000060013357,0.00020787497,0.0021042174,0.00014165652,0.0021461186,0.8536032,0.0006320553,0.07576099,0.000045355442],"about_ca_topic_score_codex":0.00083864166,"about_ca_topic_score_gemma":0.0013297201,"teacher_disagreement_score":0.002461337,"about_ca_system_score_codex":0.00036269933,"about_ca_system_score_gemma":0.00028080362,"threshold_uncertainty_score":0.008234024},"labels":[],"label_agreement":null}]}