{"meta":{"query_hash":"f365fca433ca","filters":{"topic":"Synthesis and pharmacology of benzodiazepine derivatives"},"cohort_total":78,"direct_labels_cover":0,"predictions_cover":78,"exported":78,"export_cap":100000,"truncated":false,"label_status":"direct model label, unvalidated","prediction_status":"machine_predicted_unvalidated (Codex and Gemma teacher distillation)","score_status":"score_only:v0-immature-baseline","snapshot":{"source":"OpenAlex, pinned release, all 482 partitions","release":"2026-06-24","frame_built":"2026-07-12"},"permalink":"https://metacan.xera.ac/q/f365fca433ca","api":"https://metacan.xera.ac/api/v1/cohort?topic=Synthesis+and+pharmacology+of+benzodiazepine+derivatives"},"results":[{"id":"W1754922100","doi":"10.1515/hc.2002.8.1.19","title":"Design and Synthesis of Novel Pyrrolo[2,1-c][1,4]benzodiazepine - Imidazole Containing Polyamide Conjugates","year":2002,"lang":"en","type":"article","venue":"Heterocyclic Communications","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Imidazole; Chemistry; Polyamide; Conjugate; Benzodiazepine; Combinatorial chemistry; Stereochemistry; Organic chemistry; Receptor; Biochemistry","score_opus":0.0879943772564784,"score_gpt":0.2983913620527311,"score_spread":0.21039698479625268,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1754922100","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.96390945,0.008641116,0.0025419786,0.0047087707,0.000053741325,0.00031242977,0.00014180913,0.00024661864,0.019444091],"genre_scores_gemma":[0.98383963,0.0025801952,0.0130344555,0.00019364661,0.000029487817,0.00018047038,0.000012824775,0.000033870492,0.000095421434],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99862784,0.00012623213,0.00054029265,0.00027634198,0.00013198708,0.00029732712],"domain_scores_gemma":[0.9948823,0.0034587835,0.00030784003,0.0011578475,0.00007125854,0.000122005025],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000204428,0.00023700715,0.00044792268,0.000119300465,0.00032165894,0.00003189787,0.000771122,0.00013230563,0.0014859423],"category_scores_gemma":[0.00038255952,0.00024663046,0.00009782576,0.00012606877,0.00057965156,0.00015932653,0.0003404639,0.00025572986,0.000021783924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00004610652,0.0007818304,0.0014422638,0.000084259234,0.00025722006,0.0000012795325,0.0014779354,0.00008644799,0.97992647,0.0004559996,0.000386313,0.015053859],"study_design_scores_gemma":[0.0015682477,0.00007315431,0.0019643093,0.00034203878,0.00023071734,0.000050011804,0.0008541617,0.074037865,0.9120306,0.00013105404,0.008143688,0.0005741951],"about_ca_topic_score_codex":0.000060373397,"about_ca_topic_score_gemma":0.000009237211,"teacher_disagreement_score":0.07395142,"about_ca_system_score_codex":0.000028518381,"about_ca_system_score_gemma":0.0000098599485,"threshold_uncertainty_score":0.99999857},"labels":[],"label_agreement":null},{"id":"W1819808716","doi":"10.1139/v11-108","title":"Development of a copper(II)-catalyzed three-component tandem synthesis of isoindolinone derivatives","year":2011,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":32,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Chemistry; Alkyne; Propargyl; Tandem; Combinatorial chemistry; DNA gyrase; Catalysis; Amine gas treating; Aldehyde; Cascade reaction; Organic chemistry; Biochemistry","score_opus":0.03773786385963178,"score_gpt":0.23744947564232916,"score_spread":0.19971161178269736,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1819808716","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9867194,0.00088119955,0.00004284166,0.00007477228,0.0000653289,0.0000366455,0.000049006132,0.000005863519,0.012124897],"genre_scores_gemma":[0.9950062,0.000026533122,0.0047523375,0.000016087022,0.00009810878,0.0000069852344,0.0000055158866,0.000025641479,0.00006256569],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981781,0.000018963321,0.001043987,0.00018053985,0.00023665249,0.00034171055],"domain_scores_gemma":[0.99769837,0.00016899174,0.0010782323,0.00023940016,0.00031574702,0.00049925793],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00032773125,0.0002454911,0.0006818682,0.00011304983,0.00013672328,0.0000068575,0.00059007894,0.00018521937,0.0047293035],"category_scores_gemma":[0.00031408414,0.0002358585,0.00021905995,0.00012823366,0.00039646577,0.00009793703,0.00004188061,0.00026468837,0.0000023195082],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008760865,0.00014038113,0.01037836,0.0002947487,0.00052252744,0.00004517097,0.004452375,0.0000022627942,0.97950166,0.000008839397,0.00028077906,0.0042852764],"study_design_scores_gemma":[0.00053032,0.00001310244,0.0072904374,0.0004518473,0.00007765653,0.000074157186,0.0012424923,0.0000068837094,0.988633,0.000073261755,0.0013909601,0.0002159251],"about_ca_topic_score_codex":0.00025224936,"about_ca_topic_score_gemma":0.00034264423,"teacher_disagreement_score":0.012062332,"about_ca_system_score_codex":0.0001265419,"about_ca_system_score_gemma":0.0018371353,"threshold_uncertainty_score":0.99618053},"labels":[],"label_agreement":null},{"id":"W1896010292","doi":"10.1002/0471264229.os089.13","title":"Catalytic IntramolecularFriedel‐Crafts Reaction of Benzyl Meldrum's Acid Derivatives: Preparation of 5,6‐Dimethoxy‐2‐Methyl‐1‐Indanone","year":2014,"lang":"en","type":"other","venue":"Organic Syntheses","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chemistry; Catalysis; Meldrum's acid; Organic chemistry","score_opus":0.016788889021376877,"score_gpt":0.28451726757380225,"score_spread":0.2677283785524254,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1896010292","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.10004192,0.0077463496,0.005391164,0.00039146838,0.0010952457,0.0010488562,0.00073181454,0.00066725264,0.88288593],"genre_scores_gemma":[0.9701596,0.0006098861,0.0022890177,0.00004365425,0.0004441427,0.00006515656,0.00016019787,0.0005974169,0.02563096],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9972437,0.0002485627,0.00090815045,0.0007218821,0.000490264,0.0003874523],"domain_scores_gemma":[0.99606496,0.001004881,0.0017269399,0.00092539133,0.00015677598,0.00012103317],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00042666905,0.00062724645,0.0013532494,0.00037471554,0.00006398449,0.000019753541,0.000582326,0.00080846326,0.013981055],"category_scores_gemma":[0.0020726805,0.0006193938,0.0002788402,0.0003080353,0.00046049873,0.00011079389,0.00013771612,0.00035618624,0.00010449394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100076926,0.000249055,0.00009586147,0.0010107375,0.0008825695,0.0000037770149,0.0005500734,0.0000012071954,0.9738094,0.00009756997,0.015585124,0.0076145255],"study_design_scores_gemma":[0.000303504,0.000083319974,0.00008820633,0.0011046994,0.00040981584,0.0000122808715,0.00029900085,0.000034441593,0.9507861,0.000091816924,0.046291493,0.00049528986],"about_ca_topic_score_codex":0.00020335181,"about_ca_topic_score_gemma":0.000053336054,"teacher_disagreement_score":0.87011766,"about_ca_system_score_codex":0.000079032456,"about_ca_system_score_gemma":0.00020962337,"threshold_uncertainty_score":0.99962574},"labels":[],"label_agreement":null},{"id":"W1963559110","doi":"10.1107/s1600536807002097","title":"An unexpected<i>N</i>-substituted oxindole: 1-(3,3,5-trimethyl-2-phenyl-1,2-oxazolidin-5-yl)-1<i>H</i>-indol-3(2<i>H</i>)-one","year":2007,"lang":"en","type":"article","venue":"Acta Crystallographica Section E Structure Reports Online","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Oxindole; Isoindole; Chemistry; Ring (chemistry); Stereochemistry; Medicinal chemistry; Organic chemistry; Catalysis","score_opus":0.013808323497342269,"score_gpt":0.2798827634451523,"score_spread":0.26607443994781,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963559110","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9917891,0.0006439937,0.0012325022,0.00040472715,0.0016977887,0.00042875652,0.00024268265,0.0011603746,0.0024000697],"genre_scores_gemma":[0.9888635,0.00022941077,0.005384152,0.00047704988,0.0031499774,0.000027047943,0.0015440523,0.00018572416,0.00013905067],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.993692,0.00016623603,0.0019610533,0.0017911319,0.0010536846,0.0013358853],"domain_scores_gemma":[0.9950542,0.0003895121,0.0014975845,0.0016108634,0.0006447631,0.0008031079],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009094596,0.0010306125,0.0011473899,0.0009163297,0.00073374703,0.0001592392,0.0006438176,0.0011690526,0.0024117632],"category_scores_gemma":[0.0003890594,0.0010340887,0.00052848057,0.0018628968,0.0006104246,0.0007623306,0.00013524086,0.001689297,1.9297568e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0003752869,0.0009153418,0.013371105,0.00013599939,0.000623731,0.00056920055,0.00031130353,0.00007644065,0.97964734,0.0000118003045,0.00047332485,0.0034891348],"study_design_scores_gemma":[0.0035828443,0.00035983117,0.11245867,0.0002856278,0.00097617105,0.004304701,0.0012512859,0.00023423166,0.38236314,0.0027832466,0.4880114,0.0033888388],"about_ca_topic_score_codex":0.00023221773,"about_ca_topic_score_gemma":0.00073340576,"teacher_disagreement_score":0.5972842,"about_ca_system_score_codex":0.00016508409,"about_ca_system_score_gemma":0.00023655791,"threshold_uncertainty_score":0.99921095},"labels":[],"label_agreement":null},{"id":"W1963565708","doi":"10.1002/chin.200127032","title":"ChemInform Abstract: Competitive [3 + 2] and [2 + 2] Cycloadditions of Ester Stabilized Azaallyl Anions to Benzynes. Ring Expansion of Initial [3 + 2] Products to Isoquinolin‐3‐ones.","year":2001,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Aryne; Ring (chemistry); Service (business); Medicinal chemistry; Combinatorial chemistry; Computational chemistry; Stereochemistry; Organic chemistry; Business; Marketing","score_opus":0.02712357168525326,"score_gpt":0.3013130369580698,"score_spread":0.27418946527281657,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1963565708","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.693714,0.000085831845,0.0000012066428,0.00046567264,0.00007099297,0.00026887507,0.0002720547,0.00004908869,0.30507228],"genre_scores_gemma":[0.99729306,0.00009041453,0.0003921874,0.0001814333,0.00019050793,0.00011151201,0.0001419733,0.000030480798,0.001568429],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981772,3.3684532e-7,0.0007655182,0.00036344051,0.00029118184,0.00040235688],"domain_scores_gemma":[0.9983839,0.00027096688,0.00030798535,0.00039802282,0.00037390713,0.00026522425],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001667714,0.0003134097,0.00055604125,0.00016844086,0.000105971114,0.000020273326,0.0002799119,0.00017383808,0.0043750424],"category_scores_gemma":[0.00040449406,0.00031569932,0.00010446003,0.00032184628,0.00022753581,0.0003162735,0.0002246984,0.00020435202,0.00002168721],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00038850258,0.00027037555,0.00025297675,0.00064716284,0.00012019722,0.000010437863,0.0064450703,0.000003901667,0.84727186,0.00035971703,0.00489928,0.13933049],"study_design_scores_gemma":[0.0008774619,0.00006713672,0.0040530916,0.0003224348,0.000046981553,0.000028295584,0.0024720537,0.000005355987,0.9602591,0.000032490698,0.031505518,0.0003301031],"about_ca_topic_score_codex":0.00003897012,"about_ca_topic_score_gemma":0.000014784077,"teacher_disagreement_score":0.30357906,"about_ca_system_score_codex":0.000064101594,"about_ca_system_score_gemma":0.0001215148,"threshold_uncertainty_score":0.9999295},"labels":[],"label_agreement":null},{"id":"W1969453931","doi":"10.1039/c5ra02307f","title":"Expeditious synthesis of (±)-diethyl 2-alkyl- and 2-aryl-(3-oxoisoindolin-1-yl)phosphonates catalysed by OSU-6","year":2015,"lang":"en","type":"article","venue":"RSC Advances","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stillwater (Canada)","funders":"College of Arts and Sciences, Oklahoma State University; Oklahoma State University; National Science Foundation","keywords":"Aryl; Alkyl; Chemistry; Catalysis; Amine gas treating; Organic chemistry; Condensation; Medicinal chemistry","score_opus":0.017013048148237755,"score_gpt":0.27639939118364787,"score_spread":0.25938634303541014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1969453931","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9456977,0.04393324,0.000040358107,0.00048190227,0.00021763159,0.00008915059,0.00029899113,0.00010472541,0.009136263],"genre_scores_gemma":[0.99598724,0.0022458897,0.00083027245,0.000113056405,0.0001809597,0.00008256908,0.00004642435,0.00003505429,0.0004785357],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99855256,0.00003390707,0.00040086667,0.00041613457,0.00027339088,0.00032314574],"domain_scores_gemma":[0.99841225,0.00070740376,0.00029237304,0.00025963274,0.00011782565,0.0002104949],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019467466,0.00028073054,0.00051366445,0.000057463647,0.00009456526,0.000018946153,0.00027410634,0.00014052144,0.00049844943],"category_scores_gemma":[0.0004887493,0.00025915293,0.00008798895,0.00011177748,0.00041527193,0.000327773,0.000082966086,0.00015371598,0.000020039713],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00034511878,0.0004621963,0.009747674,0.0004775562,0.00032935574,0.000030688705,0.0022755866,0.00005246234,0.85449564,0.0001183034,0.03356661,0.098098814],"study_design_scores_gemma":[0.0006975708,0.00004376118,0.00031004922,0.00007245374,0.00006692862,0.000011381338,0.001656809,0.00007404313,0.9566992,0.00085503043,0.039206557,0.00030621648],"about_ca_topic_score_codex":0.000091507776,"about_ca_topic_score_gemma":0.000009573355,"teacher_disagreement_score":0.10220356,"about_ca_system_score_codex":0.000034860943,"about_ca_system_score_gemma":0.000059267823,"threshold_uncertainty_score":0.99998605},"labels":[],"label_agreement":null},{"id":"W1970604092","doi":"10.1016/j.ejmech.2005.02.005","title":"Design, synthesis and in vitro cytotoxic studies of novel bis-pyrrolo[2,1][1,4] benzodiazepine-pyrrole and imidazole polyamide conjugates","year":2005,"lang":"en","type":"article","venue":"European Journal of Medicinal Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Pyrrole; Imidazole; Polyamide; Stereochemistry; Combinatorial chemistry; In vitro; Conjugate; Organic chemistry; Biochemistry","score_opus":0.04219036408863442,"score_gpt":0.28745544237253745,"score_spread":0.24526507828390304,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1970604092","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9798195,0.016807217,0.000088322995,0.0013717313,0.000039246697,0.00004676758,0.000022120876,0.000014152271,0.0017909501],"genre_scores_gemma":[0.99391925,0.002423141,0.0028867878,0.00017196593,0.0004797146,0.0000035105033,0.0000015501844,0.000039309703,0.00007477318],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979128,0.00014408014,0.0010175047,0.00028013217,0.00032396222,0.00032152352],"domain_scores_gemma":[0.99737406,0.0012846458,0.0007736372,0.00017350765,0.00016380896,0.00023034174],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00159263,0.00031855295,0.0008066185,0.00012359735,0.00007415567,0.000016638685,0.00031348554,0.00007758091,0.00024352787],"category_scores_gemma":[0.0013001297,0.00026941608,0.000094466406,0.000112981026,0.00062649325,0.00016065332,0.00011679944,0.00049788144,0.0000013771333],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0007299936,0.00019057619,0.0005526937,0.0003995975,0.00025754957,0.00015043399,0.00087674346,0.000089588524,0.989567,5.719355e-7,0.00029556942,0.0068896846],"study_design_scores_gemma":[0.0019538638,0.00006683889,0.0013488575,0.0008459521,0.00016474373,0.0005381201,0.0019654173,0.0002776043,0.9917685,0.00000501497,0.0008370249,0.00022810255],"about_ca_topic_score_codex":0.0000022403208,"about_ca_topic_score_gemma":4.024051e-7,"teacher_disagreement_score":0.014384077,"about_ca_system_score_codex":0.00005185425,"about_ca_system_score_gemma":0.00007943158,"threshold_uncertainty_score":0.9999758},"labels":[],"label_agreement":null},{"id":"W1980006164","doi":"10.1039/b303650m","title":"Synthesis and cytotoxicity evaluation of novel C7–C7, C7–N3 and N3–N3 dimers of 1-chloromethyl-5-hydroxy-1,2-dihydro-3H-benzo[e]indole (seco-CBI) with pyrrole and imidazole polyamide conjugates","year":2003,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Indole test; Pyrrole; Imidazole; Stereochemistry; Cytotoxicity; Organic chemistry; In vitro; Biochemistry","score_opus":0.013984328132076769,"score_gpt":0.245338624376,"score_spread":0.23135429624392323,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1980006164","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9928821,0.0039548557,0.00042369458,0.00013039875,0.000022771184,0.00022996643,0.00015495754,0.000045622222,0.0021556623],"genre_scores_gemma":[0.9987732,0.00033496885,0.00057529757,0.0000621995,0.000037507834,0.00004512423,0.000032097265,0.00008192963,0.00005768739],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99738705,0.00011542975,0.00062382343,0.00082113635,0.0005843795,0.00046819128],"domain_scores_gemma":[0.99804425,0.0003950054,0.0005556478,0.0004997216,0.00023945731,0.0002659063],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008069913,0.00053536874,0.0007918409,0.0000865763,0.00016764991,0.000045087574,0.00025003808,0.00039412966,0.0015569903],"category_scores_gemma":[0.00071988936,0.0005226892,0.00010777217,0.00029561698,0.00083004334,0.00014936258,0.0001390046,0.00027383087,0.0000019112458],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000104839026,0.00034665858,0.0025015953,0.0006951284,0.0004903158,0.000009227376,0.00033699154,0.00001161714,0.9948097,0.000012610176,0.000022463564,0.0006588704],"study_design_scores_gemma":[0.0022569906,0.000054438893,0.0009503836,0.00028147243,0.0006594235,0.0000737588,0.0008005931,0.0017073198,0.9925502,0.00004707529,0.0000758087,0.00054255285],"about_ca_topic_score_codex":0.00006206554,"about_ca_topic_score_gemma":0.000006588799,"teacher_disagreement_score":0.0058911163,"about_ca_system_score_codex":0.00007202789,"about_ca_system_score_gemma":0.00023019873,"threshold_uncertainty_score":0.9997225},"labels":[],"label_agreement":null},{"id":"W1985108093","doi":"10.1107/s1600536801003270","title":"6,9-Methano-4-methyl-3a,4,5a,6,9,10-hexahydro-5-oxa-1<i>H</i>,3<i>H</i>-furano[3,4-<i>c</i>]isoindol-3-one","year":2001,"lang":"en","type":"article","venue":"Acta Crystallographica Section E Structure Reports Online","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto; University of Guelph","funders":"","keywords":"Chemistry; Medicinal chemistry; Computational chemistry","score_opus":0.014777489114733557,"score_gpt":0.26136250111275416,"score_spread":0.2465850119980206,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1985108093","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9845377,0.00097337295,0.00018396742,0.0019662308,0.0013894273,0.00042209736,0.00032868775,0.00092968554,0.009268824],"genre_scores_gemma":[0.98947656,0.0012838664,0.0018697529,0.00080850045,0.002580789,0.00007121686,0.0012427523,0.00020124976,0.0024653026],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9937856,0.0002342936,0.0018248765,0.0018104315,0.0010904587,0.0012543203],"domain_scores_gemma":[0.99544084,0.00044955162,0.0014658835,0.0015243404,0.00053306244,0.00058629655],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00056221324,0.0011045275,0.001319751,0.0007585769,0.0006864644,0.00016070782,0.00062419317,0.0010803108,0.016427753],"category_scores_gemma":[0.0005261292,0.0010840009,0.0007796018,0.0017282978,0.0006115217,0.0006525908,0.00022908108,0.0015171529,7.427754e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00031018053,0.0006246872,0.017211467,0.00014995006,0.00080019323,0.0005573297,0.00016930922,0.00010615919,0.9707923,0.0000036774954,0.0047528655,0.004521883],"study_design_scores_gemma":[0.0015375119,0.00017814366,0.018085886,0.00015090153,0.00050226145,0.0037618862,0.00022076539,0.00015275025,0.020213298,0.0016184405,0.95207256,0.001505585],"about_ca_topic_score_codex":0.00018027732,"about_ca_topic_score_gemma":0.00031194428,"teacher_disagreement_score":0.950579,"about_ca_system_score_codex":0.0001332501,"about_ca_system_score_gemma":0.00020221763,"threshold_uncertainty_score":0.999161},"labels":[],"label_agreement":null},{"id":"W1988251035","doi":"10.1139/v99-234","title":"Construction of bicyclic tetrahydroisoquinolinones by combination of an IMDAF-ring cleavage reaction of <i>N</i>-allyl-2-furan-2-yl-acetamides","year":2000,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"National Institutes of Health; National Science Foundation","keywords":"Chemistry; Cycloaddition; Furan; Intramolecular force; Medicinal chemistry; Amide; Bicyclic molecule; Ether; Ring (chemistry); Stereochemistry; Organic chemistry","score_opus":0.008625762964749354,"score_gpt":0.2248560797504725,"score_spread":0.21623031678572316,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1988251035","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9909707,0.0006921221,0.0000052103246,0.00009439604,0.00009746655,0.00003347116,0.000116138945,0.00000687825,0.007983642],"genre_scores_gemma":[0.99924517,0.00019507733,0.00020736034,0.0000151178265,0.0001297772,0.0000014441586,0.000029555338,0.000020870899,0.00015565263],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99851066,0.00003559444,0.0008624209,0.00015617277,0.0002161181,0.00021901967],"domain_scores_gemma":[0.9981341,0.000097336255,0.0009841013,0.00020087334,0.00029896668,0.00028466262],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00022473316,0.00017562314,0.00047841322,0.000108127126,0.00006333516,0.000011118186,0.00028525648,0.00021363769,0.001747459],"category_scores_gemma":[0.00012765193,0.00019336274,0.00016140839,0.00014936726,0.00043507892,0.00027285673,0.0000054862903,0.0002766292,7.6803957e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00009042686,0.00009138676,0.0027027735,0.00032154724,0.000120106466,0.000008719515,0.0003163884,0.000036841884,0.9764233,0.000005423778,0.00030015458,0.019582918],"study_design_scores_gemma":[0.0008585198,0.000058511134,0.0018405783,0.00024533403,0.00007447822,0.00015433284,0.0008253036,0.00006317398,0.9947281,0.000119152784,0.00088191417,0.00015063015],"about_ca_topic_score_codex":0.0008968413,"about_ca_topic_score_gemma":0.00011993532,"teacher_disagreement_score":0.019432288,"about_ca_system_score_codex":0.00008684206,"about_ca_system_score_gemma":0.00035288505,"threshold_uncertainty_score":0.99916506},"labels":[],"label_agreement":null},{"id":"W1991443131","doi":"10.2174/1389557033488097","title":"Recent Developments in Novel Pyrrolo[2,1-c][1,4]Benzodiazepine Conjugates: Synthesis and Biological Evaluation","year":2003,"lang":"en","type":"review","venue":"Mini-Reviews in Medicinal Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":26,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"DNA; Chemistry; Nucleic acid; Small molecule; Stereochemistry; Context (archaeology); Transcription (linguistics); Biochemistry; RNA; Substituent; Biological activity; Biology; In vitro; Gene","score_opus":0.18829117302946136,"score_gpt":0.3986680311449859,"score_spread":0.21037685811552453,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1991443131","genre_codex":"review","genre_gemma":"review","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"review","genre_consensus":"review","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.0021198562,0.987429,0.0000017582653,0.00010438736,0.00017534338,0.0009241061,0.000094190575,0.000031676565,0.009119675],"genre_scores_gemma":[0.00014831795,0.9957712,0.00067160913,0.00022424874,0.0002568146,0.0023265926,0.00033619517,0.000073351315,0.00019161316],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9938194,0.0005357471,0.002759174,0.001466675,0.0005861278,0.00083283643],"domain_scores_gemma":[0.99634224,0.0015488585,0.0011362275,0.000592713,0.00008827295,0.00029169544],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0044973227,0.0011898617,0.004476186,0.00021847428,0.00008668659,0.000031249747,0.0007038417,0.0012610024,0.007646034],"category_scores_gemma":[0.005055845,0.000942524,0.00032284076,0.000644204,0.00042965886,0.00008364755,0.00018272744,0.001409335,0.000053994216],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002024835,0.00031054238,0.0001498055,0.016663557,0.000117460295,0.000040002073,0.00013520151,2.0736204e-7,0.0014359304,0.0000013422267,0.00043777775,0.9806879],"study_design_scores_gemma":[0.00095676153,0.000015253446,0.00005208995,0.03421367,0.00056564383,0.00013984581,0.0001179951,0.000013030552,0.0021810587,0.000012755007,0.9608675,0.0008643547],"about_ca_topic_score_codex":0.000007629389,"about_ca_topic_score_gemma":0.0000064115197,"teacher_disagreement_score":0.9798236,"about_ca_system_score_codex":0.0008310522,"about_ca_system_score_gemma":0.00085971266,"threshold_uncertainty_score":0.9993025},"labels":[],"label_agreement":null},{"id":"W1999067617","doi":"10.1002/chin.200914138","title":"ChemInform Abstract: Novel Synthesis of 2,2‐Dialkyl‐3‐dialkylamino‐2,3‐dihydro‐1H‐naphtho[2,1‐b]pyrans.","year":2009,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acadia University","funders":"","keywords":"Chemistry; Combinatorial chemistry; Service (business); Stereochemistry; Business; Marketing","score_opus":0.01975109844303959,"score_gpt":0.2621071944709757,"score_spread":0.2423560960279361,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W1999067617","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.13443688,0.00033960672,7.8909414e-7,0.00043763217,0.0001435959,0.00015284694,0.00017668844,0.00019411807,0.86411786],"genre_scores_gemma":[0.9886215,0.00021800482,0.00018179252,0.00039160866,0.00047476517,0.00007024631,0.00008988421,0.00005101707,0.009901213],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9969058,1.3427382e-7,0.0011936204,0.00051834295,0.0005572788,0.00082484627],"domain_scores_gemma":[0.9973811,0.0006231972,0.00070776907,0.00077199703,0.00019383329,0.00032209232],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00036188803,0.0006262796,0.0009292641,0.00018203739,0.00016321788,0.000051842817,0.00090414967,0.0005457576,0.013411826],"category_scores_gemma":[0.0005650899,0.0006134862,0.0004939546,0.00030820415,0.00035066763,0.0005357505,0.00009178935,0.00045943787,0.00011792696],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012989885,0.00033227078,0.00005490178,0.0002848037,0.00013586965,0.000007415585,0.00067432533,0.0000010620442,0.47351772,0.00023690079,0.010205344,0.5144195],"study_design_scores_gemma":[0.00091872475,0.00003601479,0.0024513928,0.00021023714,0.00011839267,0.00003021625,0.00036940345,0.000027586853,0.94262284,0.00013733115,0.052433226,0.0006446417],"about_ca_topic_score_codex":0.000028443388,"about_ca_topic_score_gemma":0.0000023052207,"teacher_disagreement_score":0.85421664,"about_ca_system_score_codex":0.00013421506,"about_ca_system_score_gemma":0.00016976552,"threshold_uncertainty_score":0.99963164},"labels":[],"label_agreement":null},{"id":"W2000655631","doi":"10.1021/ol8021403","title":"Syntheses of Substituted 3-Methyleneisoindolin-1-ones By a Palladium-Catalyzed Sonogashira Coupling−Carbonylation−Hydroamination Sequence in Phosphonium Salt-Based Ionic liquids","year":2008,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":146,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Hydroamination; Sonogashira coupling; Carbonylation; Phosphonium; Phosphonium salt; Palladium; Catalysis; Combinatorial chemistry; Salt (chemistry); Organic chemistry; Ionic liquid; Ionic bonding; Ion; Carbon monoxide","score_opus":0.024050789991319568,"score_gpt":0.24797571126330417,"score_spread":0.2239249212719846,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2000655631","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9961451,0.0005635064,0.0004118558,0.0023298059,0.0001264234,0.00014831843,0.00006565677,0.00011218807,0.000097137476],"genre_scores_gemma":[0.9986787,0.00019977296,0.00036070374,0.00041187115,0.00008211734,0.000047083453,0.00014260084,0.000054667646,0.000022524146],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980792,0.00006099239,0.0006216214,0.0004933013,0.00032810363,0.00041681874],"domain_scores_gemma":[0.99829715,0.0007708861,0.00037422148,0.00037561328,0.00008614935,0.000095994685],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002794009,0.00032481804,0.00048896717,0.00018032541,0.00014102632,0.000017347444,0.0003977934,0.00020890222,0.0010703888],"category_scores_gemma":[0.0004181122,0.00034728934,0.00012109305,0.00044947455,0.00039351988,0.00020149258,0.000042043914,0.00028904015,0.000027757025],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000108912565,0.00019063371,0.008331828,0.00009491673,0.00006393325,0.00003338701,0.00049642334,0.00067500165,0.989484,0.000013233614,0.00037172262,0.0001359664],"study_design_scores_gemma":[0.0011446116,0.000016696411,0.002493637,0.0001400331,0.000042255557,0.000012898485,0.00007325615,0.0056156754,0.98997724,0.000007734668,0.00013283352,0.00034315302],"about_ca_topic_score_codex":0.00019432552,"about_ca_topic_score_gemma":0.000026879663,"teacher_disagreement_score":0.0058381916,"about_ca_system_score_codex":0.00024735148,"about_ca_system_score_gemma":0.00024437733,"threshold_uncertainty_score":0.9998979},"labels":[],"label_agreement":null},{"id":"W2005862705","doi":"10.3390/m461","title":"2-(cyclooct-2-enyloxy)-isoindole-1,3-dione","year":2006,"lang":"en","type":"article","venue":"Molbank","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Chemistry; Acetonitrile; Isoindole; Nitrogen; Nuclear chemistry; Organic chemistry","score_opus":0.007901432737235103,"score_gpt":0.22413212351627682,"score_spread":0.21623069077904172,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2005862705","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8108567,0.001039246,0.00007260714,0.0008959986,0.00013943666,0.00004141128,0.000022919527,0.00018898209,0.18674272],"genre_scores_gemma":[0.98920953,0.000026152005,0.00057266204,0.00028571268,0.0007625964,0.000035284287,0.000050511582,0.000032546886,0.009025031],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9989092,0.00001733809,0.00025423814,0.00030532366,0.00017777755,0.0003361261],"domain_scores_gemma":[0.99943584,0.000096864525,0.000098854885,0.00027280967,0.00004242325,0.00005321688],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009239839,0.00019644575,0.00022651919,0.00004105749,0.00013544044,0.000033084525,0.00023510309,0.00013563762,0.008470588],"category_scores_gemma":[0.000018403269,0.00019141412,0.000115393,0.00010460536,0.00010547494,0.00010610322,0.00005573376,0.00018162727,0.00043994645],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006270194,0.00037552806,0.0122376885,0.000113258255,0.00010391176,0.00010307535,0.0000736171,0.00008906897,0.8990765,0.0029238022,0.0745016,0.01033921],"study_design_scores_gemma":[0.0009624194,0.000013821111,0.018198432,0.00004954617,0.000045953268,0.000026235959,0.00006494594,0.00028338237,0.7194276,0.0022866451,0.25823486,0.00040618877],"about_ca_topic_score_codex":0.00014216318,"about_ca_topic_score_gemma":0.000007640678,"teacher_disagreement_score":0.18373325,"about_ca_system_score_codex":0.000031699572,"about_ca_system_score_gemma":0.000023668896,"threshold_uncertainty_score":0.9924358},"labels":[],"label_agreement":null},{"id":"W2013051244","doi":"10.1002/chin.200932174","title":"ChemInform Abstract: A Convenient Synthesis of Indolo‐ and Pyrrolobenzazepines via a Threefold Norbornene‐Mediated Domino Reaction.","year":2009,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Domino; Combinatorial chemistry; Norbornene; Organic chemistry; Catalysis","score_opus":0.014756547720552857,"score_gpt":0.24603020172300386,"score_spread":0.231273654002451,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2013051244","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.5531237,0.00044090915,1.4852483e-7,0.0004517709,0.00006678331,0.00013520775,0.00006393187,0.0001171314,0.44560042],"genre_scores_gemma":[0.9976871,0.0003463822,0.000048283462,0.00029188726,0.00016811612,0.00006258931,0.0000593745,0.00002295871,0.001313328],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99815285,2.1451005e-7,0.0007592645,0.00035095646,0.00028931053,0.00044741915],"domain_scores_gemma":[0.99812734,0.0005504255,0.0005713345,0.00038293278,0.00014648728,0.00022150694],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002369317,0.00039033065,0.00063338084,0.00012087059,0.000100786056,0.000025750269,0.0003133648,0.00035608766,0.00249219],"category_scores_gemma":[0.0004431033,0.00035846562,0.00017439347,0.00017969203,0.00026376257,0.00034573907,0.00006964787,0.00028625943,0.000034968605],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027427982,0.00018831964,0.00032079197,0.00027595542,0.00014845244,0.000007947549,0.0006381919,1.2721239e-7,0.52960116,0.000051107152,0.0039195125,0.46457416],"study_design_scores_gemma":[0.0009127421,0.000042116768,0.015378568,0.00013011391,0.00009135585,0.000027815784,0.00032897058,0.00004137161,0.9695448,0.00014289595,0.0129872635,0.00037198392],"about_ca_topic_score_codex":0.00003829768,"about_ca_topic_score_gemma":0.0000027495516,"teacher_disagreement_score":0.46420217,"about_ca_system_score_codex":0.00007567111,"about_ca_system_score_gemma":0.00007512591,"threshold_uncertainty_score":0.99988675},"labels":[],"label_agreement":null},{"id":"W2024320050","doi":"10.1021/jo701467d","title":"1,3,5-Trisubstituted 1,4-Diazepin-2-ones","year":2007,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Fonds Québécois de la Recherche sur la Nature et les Technologies","keywords":"Annulation; Chemistry; Yield (engineering); Alkyl; Substituent; Amination; Sequence (biology); Reductive amination; Medicinal chemistry; Organic chemistry; Stereochemistry; Catalysis; Materials science; Biochemistry","score_opus":0.013931545977932643,"score_gpt":0.26291723443867826,"score_spread":0.24898568846074562,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2024320050","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9851002,0.0017508683,0.0005367339,0.0007515001,0.0001896243,0.000021787637,0.000004398535,0.00003110867,0.011613749],"genre_scores_gemma":[0.9971963,0.00032857983,0.00023330834,0.00014391897,0.001228884,3.9410432e-7,0.0000023339571,0.000027710117,0.0008385727],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985999,0.000022840453,0.00063266134,0.00011106924,0.0003177432,0.00031582135],"domain_scores_gemma":[0.998093,0.00065243494,0.0006221082,0.00028284817,0.00019315032,0.00015645854],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0011432858,0.0001957874,0.0003107006,0.000029725772,0.00014474338,0.000018224038,0.000689209,0.00015306866,0.014030506],"category_scores_gemma":[0.00039092192,0.0001350034,0.0001529716,0.00018717264,0.00020580443,0.000100576384,0.000070373964,0.00057233573,0.000028892606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017179645,0.000091214846,0.0007491177,0.000056457728,0.00016593834,0.000052691707,0.0003661339,0.0000042941533,0.99395216,0.000003613634,0.002332612,0.0020539912],"study_design_scores_gemma":[0.00066144357,0.000010831866,0.0011292163,0.000055916735,0.00013457425,0.0008122105,0.00083231204,0.0000064434726,0.9825225,0.000109176115,0.013569523,0.0001558491],"about_ca_topic_score_codex":0.0000023261703,"about_ca_topic_score_gemma":0.0000014131125,"teacher_disagreement_score":0.0140016135,"about_ca_system_score_codex":0.000080860336,"about_ca_system_score_gemma":0.00012671351,"threshold_uncertainty_score":0.9868708},"labels":[],"label_agreement":null},{"id":"W2026308999","doi":"10.1002/mrc.1298","title":"Solution <sup>1</sup>H and <sup>13</sup>C NMR of new chiral 1,4‐oxazepinium heterocycles and their intermediates from the reaction of 2,4‐pentanedione with α‐<scp>L</scp>‐amino acids and (<i>R</i>)‐(—)‐2‐phenylglycinol","year":2003,"lang":"en","type":"article","venue":"Magnetic Resonance in Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Boron trifluoride; Nuclear magnetic resonance spectroscopy; Medicinal chemistry; Stereochemistry; Amino acid; Organic chemistry; Catalysis","score_opus":0.011570960508321992,"score_gpt":0.217884411719249,"score_spread":0.206313451210927,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2026308999","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97947556,0.018642722,0.000013124336,0.00016610019,0.000016182963,0.00015096864,0.000105298364,0.000025435213,0.0014046265],"genre_scores_gemma":[0.9957243,0.0031656357,0.00039122067,0.00005860146,0.0001485695,0.00003733826,0.00003448956,0.0000332621,0.0004065867],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981987,0.00007347854,0.0005550509,0.0005798633,0.00022137257,0.00037152268],"domain_scores_gemma":[0.99820733,0.0009339894,0.00030110907,0.00037017948,0.00005502288,0.00013234594],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00019971795,0.00039442792,0.0005596908,0.00003660251,0.00009485493,0.000036389454,0.00023489966,0.00026295765,0.0001386609],"category_scores_gemma":[0.0003106746,0.0003000007,0.000060298393,0.00013553338,0.00082332763,0.00015734996,0.000115734605,0.00038387443,6.8126735e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002464966,0.0001872571,0.1382625,0.00045442744,0.00007845145,0.000010323391,0.0072733066,0.000050801136,0.82523084,0.000012006894,0.00053894497,0.02765466],"study_design_scores_gemma":[0.0026691318,0.00013486305,0.075269476,0.0005894852,0.00008151792,0.0001021988,0.007360032,0.0018941436,0.9066259,0.0005661799,0.0044666096,0.00024041343],"about_ca_topic_score_codex":0.00024686658,"about_ca_topic_score_gemma":0.000018260547,"teacher_disagreement_score":0.08139512,"about_ca_system_score_codex":0.000032173168,"about_ca_system_score_gemma":0.00006181854,"threshold_uncertainty_score":0.9999452},"labels":[],"label_agreement":null},{"id":"W2029266370","doi":"10.1002/chin.200714130","title":"A BF<sub>3</sub>‐Mediated Nitrogen‐to‐Carbon Rearrangement of N‐Protected 2,3‐Dihydro‐3‐hydroxy‐1H‐benzisoindol‐1‐ones, and Its Interception for a Facile Preparation of 3‐Substituted Benzisoindolones.","year":2007,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Guelph","funders":"","keywords":"Chemistry; Interception; Nitrogen; Carbon fibers; Combinatorial chemistry; Medicinal chemistry; Organic chemistry; Algorithm; Computer science","score_opus":0.02099797880039511,"score_gpt":0.28016303307416185,"score_spread":0.25916505427376674,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2029266370","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99265397,0.0002625116,0.00006242447,0.00005660398,0.000078983016,0.0008657296,0.0001865751,0.00008355568,0.005749632],"genre_scores_gemma":[0.9989186,0.00006994462,0.00018148783,0.00003787565,0.00010838518,0.00025292923,0.00032032828,0.000031642052,0.00007880802],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99805355,0.0000032723594,0.00087337516,0.00037809988,0.0002846332,0.00040707688],"domain_scores_gemma":[0.99843967,0.00026400387,0.0005521578,0.00026400306,0.0003083903,0.00017176311],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000472879,0.00031837588,0.00053920405,0.00022782863,0.000072002986,0.000012557099,0.00020448735,0.00030210413,0.0001371046],"category_scores_gemma":[0.00044524405,0.000327879,0.00014066984,0.0002936764,0.00011521791,0.00016393981,0.00008713194,0.00016451417,0.0000065555882],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0011567891,0.00015364646,0.000297062,0.00066756696,0.00017295143,0.0000013239193,0.0023131147,0.000007585408,0.9791399,0.000020277397,0.0002835214,0.015786227],"study_design_scores_gemma":[0.001814077,0.0001641683,0.00064909435,0.00020308244,0.00009719789,0.000007222391,0.00039915505,0.0015041548,0.993932,0.000060653234,0.0008666873,0.00030252305],"about_ca_topic_score_codex":0.000031433297,"about_ca_topic_score_gemma":0.00004715608,"teacher_disagreement_score":0.0154837025,"about_ca_system_score_codex":0.00010198217,"about_ca_system_score_gemma":0.000070803966,"threshold_uncertainty_score":0.9999173},"labels":[],"label_agreement":null},{"id":"W2038216881","doi":"10.1002/adsc.200700500","title":"Efficient Preparation of the Isoindoline Framework <i>via</i> a Six Component, Tandem Double A<sup>3</sup>‐Coupling and [2+2+2] Cycloaddition Reaction","year":2008,"lang":"en","type":"article","venue":"Advanced Synthesis & Catalysis","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":72,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Cycloaddition; Isoindoline; Chemistry; Alkyne; Tandem; Aldehyde; Catalysis; Amine gas treating; Combinatorial chemistry; Cascade reaction; Bromide; Coupling reaction; Organic chemistry","score_opus":0.015662183293493594,"score_gpt":0.270047711159994,"score_spread":0.25438552786650037,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2038216881","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99673975,0.00062126596,0.0012119035,0.0002828194,0.0000671655,0.00020032347,0.000051509905,0.0000871304,0.0007381329],"genre_scores_gemma":[0.9977313,0.00036896465,0.0013521626,0.000055589462,0.00014813115,0.0001672088,0.00006198349,0.00003590841,0.00007869403],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99812764,0.00005528275,0.000596947,0.00053844217,0.00037766382,0.00030404128],"domain_scores_gemma":[0.9975261,0.0011158,0.0005541505,0.0005813785,0.00013125477,0.00009130978],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023966031,0.00030376858,0.0005341356,0.00010509989,0.0005700524,0.000014914132,0.0002532547,0.00020528177,0.00025488334],"category_scores_gemma":[0.00034839724,0.00025545812,0.00025511804,0.00037640403,0.00031395495,0.00016262078,0.00009187832,0.0002754972,0.0000122114525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004767068,0.0004898883,0.004312272,0.00010773149,0.0003639968,0.0000047268545,0.0015725691,0.09040208,0.89698476,0.000060140344,0.00010112008,0.00512401],"study_design_scores_gemma":[0.0006274281,0.00001871189,0.0031938695,0.00021679886,0.00035929968,0.000038145317,0.0004137304,0.0496642,0.9442097,0.00012153683,0.00081833894,0.00031823607],"about_ca_topic_score_codex":0.000064322645,"about_ca_topic_score_gemma":0.000007453385,"teacher_disagreement_score":0.04722495,"about_ca_system_score_codex":0.000092159855,"about_ca_system_score_gemma":0.000039661947,"threshold_uncertainty_score":0.99998975},"labels":[],"label_agreement":null},{"id":"W2053591350","doi":"10.1002/chin.201011158","title":"ChemInform Abstract: One‐Pot Construction of Isoindolo[2,1‐a]quinoline System.","year":2010,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Steacie Institute for Molecular Sciences; University of Ottawa","funders":"","keywords":"Chemistry; Quinoline; Service (business); Combinatorial chemistry; Organic chemistry; Business; Marketing","score_opus":0.0179704131232586,"score_gpt":0.2544685051534805,"score_spread":0.23649809203022193,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2053591350","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.35146132,0.000052606716,1.3059893e-7,0.000070970586,0.0002543448,0.00006500598,0.00005445501,0.00010778815,0.64793336],"genre_scores_gemma":[0.99330765,0.0000455408,0.00034717048,0.000043535114,0.00052366086,0.000039946262,0.000098933124,0.000027070213,0.0055664983],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984216,5.995967e-8,0.0007031764,0.00024090336,0.00027007548,0.00036417198],"domain_scores_gemma":[0.99852115,0.00016327642,0.0005403623,0.0004368848,0.00018066051,0.00015764261],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020316418,0.00026926122,0.00045586476,0.0000865867,0.00009362153,0.000022843933,0.00037320922,0.0003818753,0.013074102],"category_scores_gemma":[0.00015530971,0.0002668646,0.00017326057,0.00012743141,0.0004013178,0.00026465792,0.00008320268,0.0005008313,0.00009309109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000071542054,0.000089738445,0.00028542086,0.00096376135,0.0001193661,0.0000024625706,0.00037206136,8.880375e-8,0.69596964,0.0010819209,0.0045299213,0.29651403],"study_design_scores_gemma":[0.0007022019,0.00001247889,0.0008919053,0.0001110901,0.000049730574,0.00007058961,0.0010352853,0.000014937762,0.9599447,0.000044162574,0.036856517,0.00026637648],"about_ca_topic_score_codex":0.000019362435,"about_ca_topic_score_gemma":0.0000040896352,"teacher_disagreement_score":0.6423669,"about_ca_system_score_codex":0.00005392927,"about_ca_system_score_gemma":0.000105160296,"threshold_uncertainty_score":0.99997836},"labels":[],"label_agreement":null},{"id":"W2056466869","doi":"10.1021/jo301958q","title":"Regio- and Stereoselective Synthesis of Cyclic Imidates via Electrophilic Cyclization of 2-(1-Alkynyl)benzamides. A Correction","year":2012,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":77,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; Iowa State University; Ryerson University; University of Kansas","keywords":"Electrophile; Stereoselectivity; Chemistry; Amide; Stereochemistry; Organic chemistry; Catalysis","score_opus":0.008212000574632268,"score_gpt":0.2302476725942878,"score_spread":0.22203567201965554,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2056466869","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99598205,0.0025098782,0.0002770331,0.00017788284,0.0000834227,0.0000393196,0.000005256036,0.000010602207,0.00091455405],"genre_scores_gemma":[0.9984525,0.0010454148,0.00007096465,0.000018697838,0.00027962014,0.0000020566688,0.0000018946765,0.000026612757,0.000102251564],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987615,0.000079428486,0.0006077633,0.00010242422,0.00022449864,0.00022441843],"domain_scores_gemma":[0.99743813,0.00082434353,0.0012351787,0.00020044058,0.00021244003,0.00008944023],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00053412194,0.0001824822,0.0004347925,0.0000578926,0.00007453613,0.000006533148,0.0002604476,0.00013914853,0.0011187191],"category_scores_gemma":[0.0005757539,0.00013809485,0.000106713516,0.00020696146,0.00018257239,0.00017117997,0.000051291932,0.00029958016,0.0000010455473],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002284005,0.00016789733,0.0063831746,0.00019193659,0.00027963374,6.6694804e-7,0.000983839,0.0000057298375,0.9884592,0.0000015596396,0.00019977987,0.0030981358],"study_design_scores_gemma":[0.0003250716,0.000034013578,0.004759477,0.00014861664,0.0003525421,0.00040787933,0.0007213638,0.00007445891,0.9928844,0.00010250437,0.00006807751,0.000121582365],"about_ca_topic_score_codex":0.0000076104684,"about_ca_topic_score_gemma":9.372429e-7,"teacher_disagreement_score":0.0044251666,"about_ca_system_score_codex":0.00007363642,"about_ca_system_score_gemma":0.00007043993,"threshold_uncertainty_score":0.99979436},"labels":[],"label_agreement":null},{"id":"W2059396121","doi":"10.1002/chem.201103421","title":"From Low to Very High Birefringence in Bis(2‐pyridylimino)isoindolines: Synthesis and Structure–Property Analysis","year":2012,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Natural Resources Canada; McMaster University","keywords":"Isoindoline; Birefringence; Polarizability; Crystallography; Molecule; Chemistry; Anisotropy; Crystal structure; Stereochemistry; Medicinal chemistry; Organic chemistry; Optics; Physics","score_opus":0.0186886739858678,"score_gpt":0.2435350898620727,"score_spread":0.2248464158762049,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2059396121","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99647695,0.00077119767,0.00005852084,0.0003768163,0.0001326492,0.00003608212,0.00014426014,0.000042575746,0.0019609227],"genre_scores_gemma":[0.99634755,0.00014781224,0.0012205963,0.00016395138,0.00173069,0.0000060657203,0.000020788017,0.000057420362,0.00030511947],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99785393,0.00017418209,0.0006221532,0.0004642612,0.00027330517,0.0006121763],"domain_scores_gemma":[0.9983957,0.0002644794,0.0002827421,0.00038604604,0.00007213495,0.0005989265],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00052012596,0.00038843462,0.00055466074,0.00014856391,0.0001945855,0.00013265348,0.00053883967,0.00009854358,0.006390132],"category_scores_gemma":[0.0004958572,0.000299062,0.00017795946,0.0004040333,0.0001301159,0.0002472644,0.00020161555,0.0006124192,0.00003137398],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013299275,0.00014080798,0.03523964,0.00007921243,0.0005816077,0.00018472513,0.001106974,0.0002006405,0.94721705,3.7781138e-7,0.00063113344,0.014484824],"study_design_scores_gemma":[0.00087663205,0.000014123165,0.088406526,0.00024849872,0.0006941118,0.00020113551,0.001062874,0.00067438796,0.89971846,0.00001553286,0.007285922,0.0008018133],"about_ca_topic_score_codex":0.000035166464,"about_ca_topic_score_gemma":0.00000238966,"teacher_disagreement_score":0.05316688,"about_ca_system_score_codex":0.00009233738,"about_ca_system_score_gemma":0.000050201048,"threshold_uncertainty_score":0.9999462},"labels":[],"label_agreement":null},{"id":"W2063864438","doi":"10.1139/v01-140","title":"Asymmetric synthesis of 3-aryl-substituted 2,3-dihydro-1<i>H</i>-isoindol-1-ones","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":74,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Aryl; Cleavage (geology); Nucleophile; Tandem; Ring (chemistry); Stereochemistry; Bond cleavage; Medicinal chemistry; Organic chemistry; Catalysis","score_opus":0.0152760666558687,"score_gpt":0.23275210691575426,"score_spread":0.21747604025988557,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2063864438","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9449698,0.0033795328,0.000023574696,0.0005339646,0.00018045222,0.000027343587,0.00007135963,0.000012958091,0.05080107],"genre_scores_gemma":[0.99839574,0.000337212,0.00022614324,0.00007222173,0.0004894663,0.0000047267577,0.0000065650793,0.00003314901,0.0004347587],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99825835,0.00001620407,0.0007819479,0.00020937154,0.0002715936,0.00046251056],"domain_scores_gemma":[0.9974371,0.0004513699,0.000714554,0.00029514002,0.00032255883,0.00077923795],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00030123096,0.00026514588,0.00060780335,0.00024343868,0.00012366784,0.000031881966,0.0006666174,0.0002566729,0.0055196183],"category_scores_gemma":[0.0011033606,0.00026490935,0.0003107586,0.00047067626,0.0003137009,0.00017216182,0.000019023202,0.00041611464,0.000012607188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000106630294,0.0001162899,0.031019725,0.00034668294,0.0005158625,0.00086529437,0.00023830406,0.000104590785,0.93856853,0.0000129726905,0.008109252,0.019995868],"study_design_scores_gemma":[0.0005077389,0.000010083271,0.0016669725,0.00024684882,0.00010800587,0.0006960349,0.00024767243,0.000031567437,0.9664151,0.000096562355,0.029715212,0.0002581996],"about_ca_topic_score_codex":0.0005314776,"about_ca_topic_score_gemma":0.00017597989,"teacher_disagreement_score":0.053426012,"about_ca_system_score_codex":0.00014709716,"about_ca_system_score_gemma":0.0011624848,"threshold_uncertainty_score":0.99998033},"labels":[],"label_agreement":null},{"id":"W2069953855","doi":"10.1107/s0108270105005457","title":"Ethyl 5-isopropoxy-4-methyl-β-carboline-3-carboxylate: structural determinants of benzodiazepine-receptor antagonism","year":2005,"lang":"en","type":"article","venue":"Acta Crystallographica Section C Crystal Structure Communications","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Antagonism; Benzodiazepine; Chemistry; Carboxylate; Pharmacology; Receptor; Stereochemistry; Biology; Biochemistry","score_opus":0.018799210835120414,"score_gpt":0.2914022693282597,"score_spread":0.27260305849313926,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2069953855","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9925727,0.0014767973,0.000050323615,0.0018820119,0.00046106655,0.0003501629,0.0011081068,0.00031498703,0.0017837943],"genre_scores_gemma":[0.9908227,0.0009969559,0.0064332015,0.00016852988,0.0007120381,0.0000777082,0.0005959899,0.0001028308,0.00009009676],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.996461,0.00027859322,0.001323182,0.0007316069,0.00051266013,0.0006929902],"domain_scores_gemma":[0.99549776,0.0005808513,0.00097228115,0.002221679,0.0004299839,0.0002974645],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002791042,0.000675373,0.000867068,0.0004834833,0.0008533216,0.00009245953,0.001940028,0.0006928557,0.003289536],"category_scores_gemma":[0.00023510816,0.00066165405,0.00050759135,0.00090191705,0.0012425039,0.0005688055,0.0006047825,0.0012278897,0.0000015033332],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011016192,0.00015673613,0.008236677,0.00011036542,0.0002854878,0.000001142138,0.00084227906,0.0000636335,0.98176783,0.00010036674,0.00045970254,0.0078656245],"study_design_scores_gemma":[0.0030258244,0.00023059481,0.030621594,0.00019116802,0.0004941779,0.00018161084,0.0014074388,0.005158407,0.59648424,0.0021444196,0.3581003,0.00196022],"about_ca_topic_score_codex":0.00022690269,"about_ca_topic_score_gemma":0.0006668912,"teacher_disagreement_score":0.38528356,"about_ca_system_score_codex":0.00014244972,"about_ca_system_score_gemma":0.00015060154,"threshold_uncertainty_score":0.9995835},"labels":[],"label_agreement":null},{"id":"W2075881224","doi":"10.1007/s00280-007-0544-2","title":"Identification, characterization and potent antitumor activity of ECO-4601, a novel peripheral benzodiazepine receptor ligand","year":2007,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":53,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Pharmacology; In vivo; Glioma; Receptor; Cell culture; Chemistry; Biology; Cancer research; Biochemistry; Genetics","score_opus":0.016617771239689334,"score_gpt":0.3031539496841207,"score_spread":0.28653617844443136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2075881224","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911895,0.00096849655,0.0050535537,0.0017197378,0.0003802151,0.00024539357,0.00030986598,0.000032644126,0.000100621095],"genre_scores_gemma":[0.99381334,0.003871277,0.0002968712,0.0008354354,0.00057976274,0.00009435586,0.000047915433,0.000029204388,0.0004318334],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99892783,0.00001941374,0.00033287046,0.00037273957,0.000078291094,0.00026887454],"domain_scores_gemma":[0.9991843,0.00016875638,0.00031916302,0.00009458944,0.00012441694,0.000108755],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00029760567,0.00020386642,0.00035094612,0.0000703961,0.00013931312,0.000016701824,0.00010679197,0.00014936113,0.0011051237],"category_scores_gemma":[0.000014643143,0.00020751127,0.000058310274,0.00009379995,0.00026164897,0.00014168212,0.000023403662,0.0001265683,5.127054e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00081283605,0.00019993125,0.0031187239,0.00026789092,0.00018911797,5.4792133e-7,0.0006907173,0.000002405643,0.9332615,0.000046902584,0.00032386137,0.061085533],"study_design_scores_gemma":[0.0025319606,0.000050826704,0.020983994,0.000025436848,0.00006752755,0.0000055295855,0.00004500334,0.00046645,0.95256954,0.000020031724,0.023031624,0.0002020743],"about_ca_topic_score_codex":0.000015241782,"about_ca_topic_score_gemma":0.0000046541627,"teacher_disagreement_score":0.060883462,"about_ca_system_score_codex":0.00004257722,"about_ca_system_score_gemma":0.000052034186,"threshold_uncertainty_score":0.999808},"labels":[],"label_agreement":null},{"id":"W2076262099","doi":"10.1039/c4gc02486a","title":"Efficient syntheses of substituted (±)-3-oxoisoindoline-1-carbonitriles and carboxamides using OSU-6","year":2015,"lang":"en","type":"article","venue":"Green Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":21,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stillwater (Canada)","funders":"College of Arts and Sciences, Oklahoma State University","keywords":"Catalysis; Hexagonal crystal system; Combinatorial chemistry; Mesoporous material; Mesoporous silica; Chemistry; Organic chemistry; Crystallography","score_opus":0.06925856190862717,"score_gpt":0.28397677104031294,"score_spread":0.21471820913168577,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2076262099","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98608005,0.0018992304,0.0000137052,0.00006557828,0.000051183935,0.000046377205,0.00007567028,0.00006612686,0.011702103],"genre_scores_gemma":[0.99894124,0.000022950228,0.00055934,0.000014785159,0.0002454485,0.0000088630295,0.0000115491375,0.000027615812,0.00016818754],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9987168,0.000023204084,0.00037194998,0.0003488754,0.00025045633,0.00028874754],"domain_scores_gemma":[0.9988499,0.0002839631,0.00023334759,0.0002910537,0.00014728776,0.00019444029],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001965919,0.00025450927,0.00041618396,0.000038313974,0.000065809225,0.000016317757,0.00022524694,0.00019091838,0.0002514554],"category_scores_gemma":[0.00038916102,0.0002482101,0.00008368569,0.0001256758,0.00041730716,0.000034977398,0.00012353764,0.0001768354,0.0000023218795],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007830792,0.000096018935,0.010408153,0.0003600174,0.00010773817,0.000017824426,0.00035812752,0.0004503355,0.9871943,0.000007859356,0.00004740005,0.00087393366],"study_design_scores_gemma":[0.00056104537,0.000005623546,0.00035770313,0.0001744498,0.00010055078,0.000052711985,0.00069755164,0.012450023,0.9849294,0.000052480085,0.00034434622,0.0002741139],"about_ca_topic_score_codex":0.00034020853,"about_ca_topic_score_gemma":0.0000033649326,"teacher_disagreement_score":0.012861236,"about_ca_system_score_codex":0.000056946268,"about_ca_system_score_gemma":0.00014185437,"threshold_uncertainty_score":0.999997},"labels":[],"label_agreement":null},{"id":"W2077130594","doi":"10.3762/bjoc.7.142","title":"A simple and convenient one-pot synthesis of substituted isoindolin-1-ones via lithiation, substitution and cyclization of <i>N'</i>-benzyl-<i>N,N</i>-dimethylureas","year":2011,"lang":"en","type":"article","venue":"Beilstein Journal of Organic Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Tellabs (Canada)","funders":"Cardiff University","keywords":"Chemistry; Substitution (logic); Simple (philosophy); Combinatorial chemistry; Medicinal chemistry; Computational chemistry; Organic chemistry; Programming language; Computer science","score_opus":0.019871763532588675,"score_gpt":0.2279284308086871,"score_spread":0.20805666727609842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2077130594","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9965015,0.0019670855,0.0006995415,0.000072307776,0.00005563386,0.00006506763,0.000032737582,0.000014927768,0.0005912212],"genre_scores_gemma":[0.9981866,0.0007124726,0.00090318656,0.000016701215,0.00012034849,0.0000040684895,0.000009859111,0.000025205076,0.000021548085],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9982117,0.00005598099,0.0010136709,0.0002328171,0.0002930464,0.00019280137],"domain_scores_gemma":[0.9974376,0.00032275586,0.0014112896,0.00021391551,0.0004530076,0.0001614372],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00042299248,0.00023615985,0.0006297,0.00007853768,0.00007662179,0.000012478543,0.00021825205,0.00022726545,0.0015834137],"category_scores_gemma":[0.00059973414,0.0002325092,0.00011422261,0.00018412728,0.00036935174,0.00021306552,0.00006355383,0.00021745141,7.54136e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0002504536,0.0003051619,0.025597597,0.0007306822,0.00029999937,0.000008429383,0.00077160716,0.000003509803,0.97082746,0.000041471445,0.00002160866,0.001142019],"study_design_scores_gemma":[0.0010644787,0.00003832862,0.013310092,0.000284334,0.00035232448,0.00017660132,0.00035007435,0.00007008574,0.9836279,0.00043338566,0.000093456685,0.00019893574],"about_ca_topic_score_codex":0.000028527924,"about_ca_topic_score_gemma":0.0000036955046,"teacher_disagreement_score":0.012800442,"about_ca_system_score_codex":0.000040539417,"about_ca_system_score_gemma":0.00015959275,"threshold_uncertainty_score":0.99932927},"labels":[],"label_agreement":null},{"id":"W2090600541","doi":"10.1002/chin.200920163","title":"ChemInform Abstract: 11‐Phenyl‐[b,e]‐dibenzazepine Compounds: Novel Antitumor Agents.","year":2009,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Ministry of the Environment, Conservation and Parks","funders":"","keywords":"Chemistry; Combinatorial chemistry; Stereochemistry","score_opus":0.03359333208835296,"score_gpt":0.2869631208981477,"score_spread":0.2533697888097947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2090600541","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.103241935,0.00020020481,0.000001027205,0.00076715206,0.00019334392,0.00013207979,0.00009016533,0.00030043823,0.89507365],"genre_scores_gemma":[0.9691836,0.00009130706,0.00019316246,0.0018569172,0.0007231788,0.000033359032,0.00037198453,0.00004203531,0.027504431],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975263,6.667064e-8,0.0007978276,0.00045828475,0.0004306141,0.00078694755],"domain_scores_gemma":[0.9983635,0.00016514988,0.00042082174,0.0005911574,0.0001332653,0.00032612967],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00020900399,0.0005347439,0.00060020987,0.000101974285,0.00023285503,0.00010749693,0.0007275948,0.00030752577,0.018729655],"category_scores_gemma":[0.00018899271,0.0005222996,0.00028738056,0.00022002732,0.00019560635,0.0005687193,0.0001027152,0.00040507774,0.00025559423],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0001401267,0.0007763268,0.00020882535,0.0003431544,0.00018469684,0.00003049761,0.001256387,0.0000017618516,0.42774203,0.0013480636,0.28301665,0.28495148],"study_design_scores_gemma":[0.0012485409,0.000021453303,0.0041970583,0.00007660946,0.000040634462,0.00004350556,0.00031951044,0.000030446676,0.6931181,0.00011552096,0.30028585,0.00050281506],"about_ca_topic_score_codex":0.000017600953,"about_ca_topic_score_gemma":0.0000025839315,"teacher_disagreement_score":0.8675692,"about_ca_system_score_codex":0.00015636708,"about_ca_system_score_gemma":0.000107806314,"threshold_uncertainty_score":0.99972284},"labels":[],"label_agreement":null},{"id":"W2093060989","doi":"10.3390/m459","title":"2-(1-ethyl-but-2-enyloxy)-isoindole-1,3-dione","year":2006,"lang":"en","type":"article","venue":"Molbank","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Chemistry; Acetonitrile; Isoindole; Organic chemistry; Nitrogen; Nuclear chemistry","score_opus":0.010811216430267815,"score_gpt":0.23450965939422558,"score_spread":0.22369844296395777,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093060989","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.84787035,0.0011448051,0.00008825194,0.0010635039,0.00016463867,0.00004907026,0.000032581527,0.00020713113,0.14937967],"genre_scores_gemma":[0.9869937,0.000030253994,0.000614797,0.00034579996,0.0008315291,0.000040758914,0.000058086924,0.000038193815,0.011046914],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99875635,0.000023207404,0.00028872307,0.00034683093,0.00020380766,0.0003811112],"domain_scores_gemma":[0.9993347,0.0001272618,0.00011526458,0.0003064225,0.000053666863,0.00006270788],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00011736787,0.00022447688,0.0002590437,0.000046678964,0.00015425798,0.00003854608,0.000268222,0.00016512217,0.009356753],"category_scores_gemma":[0.000025610956,0.00021976748,0.00013352727,0.00011277213,0.00012759281,0.00011774448,0.00006621349,0.00022406309,0.0005038815],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053086107,0.00027853943,0.0059280447,0.00009704441,0.000085376065,0.000092478345,0.000060518585,0.00005916668,0.94006795,0.0016793119,0.043827716,0.007770768],"study_design_scores_gemma":[0.0008715441,0.0000146285265,0.011999303,0.000045725254,0.000042642037,0.000023730185,0.00008866627,0.00023094528,0.8348998,0.0018278123,0.14957474,0.00038045523],"about_ca_topic_score_codex":0.00019951636,"about_ca_topic_score_gemma":0.000008070706,"teacher_disagreement_score":0.1391233,"about_ca_system_score_codex":0.00003828101,"about_ca_system_score_gemma":0.00003070352,"threshold_uncertainty_score":0.99154884},"labels":[],"label_agreement":null},{"id":"W2093239349","doi":"10.1021/ol020047k","title":"Design and Synthesis of Bis 1-Chloromethyl-5-hydroxy-1,2- dihydro-3<i>H</i>-benz[<i>e</i>]indole (<i>s</i><i>eco</i>-CBI)-Pyrrole Polyamide Conjugates","year":2002,"lang":"he","type":"article","venue":"Organic Letters","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":12,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Indole test; Pyrrole; Conjugate; Polyamide; Stereochemistry; Combinatorial chemistry; Medicinal chemistry; Organic chemistry","score_opus":0.016621892488868615,"score_gpt":0.21871115880934594,"score_spread":0.20208926632047733,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2093239349","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9719901,0.0109173665,0.0004656447,0.013448366,0.00055271067,0.0006232864,0.00025867228,0.00022165812,0.0015222018],"genre_scores_gemma":[0.9870911,0.0050645005,0.0014226128,0.004972337,0.00051223475,0.00008939654,0.000016609176,0.00028972907,0.0005414816],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99392617,0.0007224559,0.0015685599,0.0015351255,0.00075009704,0.0014976008],"domain_scores_gemma":[0.993185,0.003909075,0.0011013511,0.0011014565,0.00013301609,0.00057009264],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0009172399,0.001266816,0.0018917442,0.0003723103,0.00050798495,0.00018281312,0.0011047022,0.0006738162,0.021146527],"category_scores_gemma":[0.0006648195,0.001328798,0.00042978316,0.0007486759,0.0013214906,0.0004972345,0.00040522803,0.0008792638,0.0005241113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014048401,0.0006609576,0.0011546287,0.0006464811,0.0011260994,0.000114731,0.001674951,0.00005405489,0.9626495,0.000018592222,0.029149756,0.0026097596],"study_design_scores_gemma":[0.0022420639,0.00017261451,0.00036123465,0.00047906197,0.0009610145,0.0001071549,0.00038961822,0.0021053897,0.9865352,0.000041323372,0.0052750194,0.0013303029],"about_ca_topic_score_codex":0.00013933229,"about_ca_topic_score_gemma":0.0000048807,"teacher_disagreement_score":0.023885697,"about_ca_system_score_codex":0.0001924672,"about_ca_system_score_gemma":0.00011351492,"threshold_uncertainty_score":0.99891615},"labels":[],"label_agreement":null},{"id":"W2105961411","doi":"10.1039/b306685a","title":"Design, synthesis and in vitro cytotoxicity studies of novel pyrrolo [2,1][1,4] benzodiazepine-glycosylated pyrrole and imidazole polyamide conjugates","year":2003,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Polyamide; Conjugate; Imidazole; Pyrrole; Cytotoxicity; Solubility; Combinatorial chemistry; In vitro; Organic chemistry; Biochemistry","score_opus":0.024128530987367804,"score_gpt":0.2650796328397733,"score_spread":0.2409511018524055,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2105961411","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900031,0.0075482638,0.0014455051,0.00020426438,0.000023430626,0.00013863991,0.00007070562,0.00006600627,0.000500077],"genre_scores_gemma":[0.99714875,0.0009216276,0.0016371739,0.00010112655,0.000025329135,0.000047561047,0.000011814791,0.00006124197,0.00004535828],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979571,0.00008166539,0.0005934163,0.00066874566,0.00021161056,0.00048744614],"domain_scores_gemma":[0.9984171,0.00065135595,0.00028840333,0.0003647729,0.00010783394,0.00017054199],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00042244868,0.00045687193,0.00076823344,0.00007830731,0.000118718985,0.00002888289,0.00022778656,0.00032534395,0.0005643439],"category_scores_gemma":[0.0013394661,0.0004661136,0.00008808789,0.0002839233,0.00058675563,0.00009579342,0.00014371627,0.0002721898,0.0000025650206],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00017573322,0.0002793461,0.00047685916,0.00051640195,0.0003211969,0.00004518121,0.00028992788,0.000002568512,0.99767184,0.00000437218,0.000023229211,0.00019336161],"study_design_scores_gemma":[0.0011662001,0.000015482254,0.00018171126,0.00018316427,0.00013200012,0.000096847725,0.0006857923,0.00031824436,0.996657,0.000059762762,0.00006226727,0.00044148855],"about_ca_topic_score_codex":0.000016379472,"about_ca_topic_score_gemma":0.0000017961158,"teacher_disagreement_score":0.007145659,"about_ca_system_score_codex":0.0000704105,"about_ca_system_score_gemma":0.0001020022,"threshold_uncertainty_score":0.99977905},"labels":[],"label_agreement":null},{"id":"W2147817805","doi":"10.1002/cctc.201500744","title":"Back Cover: Heterogeneously Catalyzed Hydrogenation of Squalene to Squalane under Mild Conditions (ChemCatChem 14/2015)","year":2015,"lang":"en","type":"paratext","venue":"ChemCatChem","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"SiliCycle (Canada); Université Laval","funders":"","keywords":"Squalane; Squalene; Catalysis; Biomass (ecology); Chemistry; Cover (algebra); Organic chemistry; Engineering; Biology","score_opus":0.0412585103925604,"score_gpt":0.32549689677326465,"score_spread":0.28423838638070426,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2147817805","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.85628545,0.0055723763,0.000110939494,0.00197182,0.0013834266,0.00083132606,0.0068996,0.00015444764,0.1267906],"genre_scores_gemma":[0.76437587,0.0008090109,0.0009087264,0.0011149952,0.0018702587,0.0005720731,0.02138495,0.0004701065,0.20849404],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9951305,0.00009716776,0.0014799709,0.0014330603,0.0008890187,0.00097029196],"domain_scores_gemma":[0.9952372,0.0004901911,0.0011900228,0.0014466501,0.00087108725,0.0007648575],"candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000394173,0.0012102633,0.0019105249,0.0003085628,0.00016323655,0.00006900696,0.0012569955,0.0014824468,0.05369792],"category_scores_gemma":[0.00017676815,0.001323899,0.00059613225,0.0005419613,0.00042497212,0.00018128718,0.00040171522,0.0008122731,0.021642512],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000100330435,0.00038377588,0.000019689967,0.0007188752,0.0006010872,0.0000047746826,0.00089622615,0.0002053762,0.47770634,0.000004722227,0.5192016,0.00015719623],"study_design_scores_gemma":[0.0015008958,0.000043093118,0.00001471834,0.0003199727,0.00029319755,0.00003354692,0.00037635484,0.00004807923,0.8115124,0.000060023813,0.18471275,0.0010849547],"about_ca_topic_score_codex":0.00015085269,"about_ca_topic_score_gemma":0.000018957646,"teacher_disagreement_score":0.33448884,"about_ca_system_score_codex":0.00058802037,"about_ca_system_score_gemma":0.00077027676,"threshold_uncertainty_score":0.99981385},"labels":[],"label_agreement":null},{"id":"W2156123265","doi":"10.3762/bjoc.10.81","title":"Aza-Diels–Alder reaction between <i>N</i>-aryl-1-oxo-1<i>H</i>-isoindolium ions and <i>tert</i>-enamides: Steric effects on reaction outcome","year":2014,"lang":"en","type":"article","venue":"Beilstein Journal of Organic Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Acadia University","funders":"Natural Sciences and Engineering Research Council of Canada; Nova Scotia Health Research Foundation","keywords":"Chemistry; Steric effects; Aryl; Anhydrous; Medicinal chemistry; Diels–Alder reaction; Lewis acids and bases; Stereochemistry; Reaction mechanism; Organic chemistry; Catalysis","score_opus":0.01496667282237816,"score_gpt":0.26003491693962105,"score_spread":0.2450682441172429,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2156123265","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.994797,0.00042385544,0.00009806946,0.0007755135,0.0003125407,0.000080773694,0.000013708003,0.000073286734,0.00342529],"genre_scores_gemma":[0.9967363,0.00024432526,0.00018763743,0.00030031768,0.0018368704,0.000008318015,0.000019610681,0.00007926001,0.00058736774],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975461,0.00009195744,0.0010048542,0.0004425798,0.00045023882,0.00046431666],"domain_scores_gemma":[0.9969162,0.0010657689,0.0010376514,0.0004159406,0.00018672629,0.00037772028],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006394244,0.00046975198,0.0008125475,0.00009652947,0.0002638829,0.00007702879,0.00037839016,0.00037854866,0.00041402614],"category_scores_gemma":[0.00066687976,0.00043141752,0.00025831079,0.00020093296,0.0001894798,0.00033844786,0.000095360505,0.0009748546,0.00002322593],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000117957905,0.0001429184,0.01920198,0.0005856836,0.0002187877,0.000031377225,0.00021741555,9.4395364e-7,0.9663794,0.000002041754,0.0005725799,0.012528912],"study_design_scores_gemma":[0.0022089821,0.00017255399,0.024512574,0.0005135665,0.00034126852,0.00047949768,0.00021867707,0.0000112804355,0.96434015,0.0001558361,0.0066093775,0.00043622276],"about_ca_topic_score_codex":0.000006253794,"about_ca_topic_score_gemma":0.0000011540247,"teacher_disagreement_score":0.012092689,"about_ca_system_score_codex":0.0002069617,"about_ca_system_score_gemma":0.00008309426,"threshold_uncertainty_score":0.99981374},"labels":[],"label_agreement":null},{"id":"W2159149981","doi":"10.1139/v04-153","title":"Synthesis and characterization of a series of 4-methyl-1-[2-aryl-1-diazenyl]-1,4-diazepanes and 1,4-di-[2-aryl-1-diazenyl]-1,4-diazepanes","year":2004,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":24,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Dalhousie University","keywords":"Chemistry; Aryl; Triazene; Proton NMR; Carbon-13 NMR; Salt (chemistry); Nuclear magnetic resonance spectroscopy; Stereochemistry; Crystallography; Organic chemistry; Alkyl","score_opus":0.010632799743204207,"score_gpt":0.21348127078065907,"score_spread":0.20284847103745485,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2159149981","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99386156,0.0028566555,0.0000100553425,0.0013974432,0.00014086379,0.000093260496,0.00045855774,0.000019387473,0.0011622049],"genre_scores_gemma":[0.99761957,0.0013926107,0.0003119034,0.00008762872,0.00032995144,0.000014111025,0.000032652762,0.0000665048,0.00014506925],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974202,0.000039927905,0.0012308647,0.000410923,0.000344096,0.00055400835],"domain_scores_gemma":[0.99661756,0.00037870253,0.0013068353,0.00036994403,0.00046402856,0.0008629144],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004325799,0.00049470284,0.0011520899,0.00028382178,0.00018514943,0.00006608844,0.00048229564,0.0004484269,0.0010216113],"category_scores_gemma":[0.0006690579,0.00050301524,0.00025363202,0.00028692564,0.0010924444,0.0005259719,0.00006265995,0.00045508737,0.0000013481211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014695624,0.00007824325,0.013069436,0.0011969245,0.0003683387,0.00012724317,0.0016205121,0.000028164826,0.9800058,0.00003804997,0.00010026773,0.0032200518],"study_design_scores_gemma":[0.0009774736,0.00007183095,0.011727824,0.0007530295,0.00025775473,0.0006837586,0.0012983115,0.000014833338,0.9810237,0.0003774562,0.002364635,0.0004493891],"about_ca_topic_score_codex":0.0007944393,"about_ca_topic_score_gemma":0.0002453428,"teacher_disagreement_score":0.0037579965,"about_ca_system_score_codex":0.000118401105,"about_ca_system_score_gemma":0.0011220522,"threshold_uncertainty_score":0.9998916},"labels":[],"label_agreement":null},{"id":"W2167045189","doi":"10.1007/978-0-387-73657-0_84","title":"Synthesis of pyrrolo[3,2-e][1,4]diazepin-2-ones as potential γ-turn mimetics","year":2009,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Turn (biochemistry); Chemistry; Combinatorial chemistry; Stereochemistry; Biochemistry","score_opus":0.02017006533322392,"score_gpt":0.3580057181352081,"score_spread":0.3378356528019842,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2167045189","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.93054336,0.05526342,0.000013074707,0.0014021829,0.00020239827,0.000066140885,0.0000092204045,0.000024356907,0.012475864],"genre_scores_gemma":[0.991701,0.006980701,0.00037055896,0.0006437061,0.00023312948,0.000019374085,0.000011823787,0.000008454222,0.000031226566],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99887896,0.000056187888,0.00040258045,0.00031948352,0.0000786016,0.0002641834],"domain_scores_gemma":[0.9992668,0.00032430218,0.00016621033,0.00014301295,0.000023900448,0.00007579192],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00012046923,0.00020670755,0.00050394883,0.00011207679,0.000048645736,0.0000022776971,0.00017366109,0.00014781624,0.0009804008],"category_scores_gemma":[0.0001711066,0.00015904421,0.000050220537,0.00009593833,0.00069998065,0.00010482246,0.000041720075,0.0001330515,0.000003429468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00021314954,0.00020419403,0.00200313,0.000027840706,0.00002442741,0.000014075038,0.00047174524,0.0000032060702,0.9267881,0.001003631,0.00006091564,0.069185615],"study_design_scores_gemma":[0.0008950644,0.0005840945,0.00084856746,0.00011317012,0.000028000039,0.000037506896,0.0025319797,0.00004629016,0.98397577,0.0022080867,0.008553524,0.00017796173],"about_ca_topic_score_codex":0.000031903925,"about_ca_topic_score_gemma":0.0000023541807,"teacher_disagreement_score":0.06900766,"about_ca_system_score_codex":0.000016676517,"about_ca_system_score_gemma":0.000013230589,"threshold_uncertainty_score":0.9999328},"labels":[],"label_agreement":null},{"id":"W2176025995","doi":"10.1016/j.bmcl.2004.07.001","title":"Synthesis of a novel tetrahydroisoquinolino[2,1-c][1,4]benzodiazepine ring system with DNA recognition potential","year":2004,"lang":"en","type":"article","venue":"Bioorganic & Medicinal Chemistry Letters","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":9,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Benzodiazepine; Ring (chemistry); Stereochemistry; DNA; Combinatorial chemistry; Biochemistry; Organic chemistry; Receptor","score_opus":0.014802109695932271,"score_gpt":0.21690018533970715,"score_spread":0.20209807564377488,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2176025995","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9935197,0.00021278084,0.0018374792,0.0017625346,0.00011592137,0.00011645506,0.00013578688,0.0002107682,0.002088571],"genre_scores_gemma":[0.99740803,0.000030018688,0.001312902,0.00023267865,0.0008002685,0.0000521772,0.00007267132,0.00007479899,0.00001646907],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975082,0.000020503196,0.0006755796,0.00064288935,0.0005919358,0.0005608375],"domain_scores_gemma":[0.99852455,0.00016224818,0.0005030506,0.00044248407,0.00011849377,0.0002491859],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023072571,0.00047272915,0.0006746323,0.000083886356,0.00014828244,0.00002228193,0.00046108555,0.00024909177,0.0009868554],"category_scores_gemma":[0.00016592191,0.00042526855,0.0001742363,0.00028121518,0.00044473197,0.00013182763,0.000067324036,0.000407227,0.00002049209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020732784,0.00026420428,0.00015332057,0.0013776757,0.00032341137,0.0001324609,0.00019336352,0.000087109125,0.9961252,0.000005322593,0.00007084118,0.001059746],"study_design_scores_gemma":[0.0026246002,0.000029875859,0.0004464299,0.001618236,0.0003728472,0.000621028,0.0010754139,0.00011041169,0.99256474,0.0000032052512,0.0000623712,0.00047085897],"about_ca_topic_score_codex":0.000111939546,"about_ca_topic_score_gemma":0.0000021888056,"teacher_disagreement_score":0.0038883125,"about_ca_system_score_codex":0.00029556308,"about_ca_system_score_gemma":0.00015550377,"threshold_uncertainty_score":0.9999264},"labels":[],"label_agreement":null},{"id":"W2252861824","doi":"10.1021/acs.orglett.5b02677","title":"Formal Synthesis of (+)-Lasubine II and (−)-Subcosine II via Organocatalytic Michael Addition of a Ketone to an α-Nitrostyrene","year":2015,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Michael reaction; Chemistry; Ketone; Organocatalysis; Organic chemistry; Combinatorial chemistry; Catalysis; Enantioselective synthesis","score_opus":0.014656482076209336,"score_gpt":0.2350357165325188,"score_spread":0.22037923445630947,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2252861824","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9960557,0.00009780983,0.0002164416,0.0031220366,0.00006193333,0.000095677846,0.0001392871,0.000043872045,0.00016722271],"genre_scores_gemma":[0.9979666,0.000013277905,0.00095753244,0.0007500922,0.00014516231,0.000019358065,0.000070044836,0.000042532705,0.000035384757],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99872375,0.0000360581,0.00040829272,0.00030491877,0.00022848068,0.00029849738],"domain_scores_gemma":[0.9989994,0.00012586376,0.00023296372,0.00031879733,0.0000998613,0.00022306867],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023462938,0.00022535938,0.00044664208,0.0001247781,0.00011367016,0.0000073975975,0.00023952492,0.000102757025,0.0014424169],"category_scores_gemma":[0.00022290986,0.00022269435,0.000053698328,0.00019923504,0.00017892709,0.000231019,0.00021390751,0.000111861096,0.0000117474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020465156,0.00019247425,0.00051485474,0.000096615215,0.0001072656,0.000004850863,0.0014351276,0.0000038596168,0.99151605,0.000007833265,0.0023526133,0.0035638106],"study_design_scores_gemma":[0.0008164294,0.00024749414,0.0014155726,0.00006798192,0.00013089758,0.00003127438,0.00026451336,0.000111825226,0.9962969,0.00002870944,0.0003606864,0.00022773385],"about_ca_topic_score_codex":0.000042604708,"about_ca_topic_score_gemma":0.000008318247,"teacher_disagreement_score":0.0047808383,"about_ca_system_score_codex":0.00006061202,"about_ca_system_score_gemma":0.000056715253,"threshold_uncertainty_score":0.9994704},"labels":[],"label_agreement":null},{"id":"W2331513443","doi":"10.1515/hc.2002.8.2.115","title":"Design and Synthesis of Novel DNA Interstrand Cross-Linking Agents: C2-Linked Pyrrolo[2,1-c][1,4]benzodiazepine Polyamide Conjugates","year":2002,"lang":"en","type":"article","venue":"Heterocyclic Communications","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Conjugate; Benzodiazepine; Combinatorial chemistry; Polyamide; Stereochemistry; DNA; Organic chemistry; Biochemistry; Receptor","score_opus":0.10440611366749933,"score_gpt":0.32924628491534846,"score_spread":0.22484017124784914,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2331513443","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9863543,0.0034546272,0.0020409003,0.0020278986,0.000064617816,0.00025967095,0.00013040025,0.00016065547,0.0055069136],"genre_scores_gemma":[0.98738223,0.003159708,0.008766454,0.00024935463,0.00004501146,0.00016045639,0.000033946264,0.000045830533,0.00015701324],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9981352,0.00015844945,0.0007681486,0.00038150686,0.00019001623,0.0003666454],"domain_scores_gemma":[0.9954035,0.0025782534,0.00040590495,0.0013650402,0.0001013119,0.00014596393],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002906566,0.00031769104,0.00053208583,0.00015428751,0.00042361135,0.00008698618,0.0011949214,0.00020033731,0.0016115349],"category_scores_gemma":[0.00029847358,0.00032952402,0.00015695588,0.00015617683,0.00093818345,0.00024352831,0.0004426276,0.0003548162,0.000024489946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0000795207,0.0011656611,0.0039104815,0.00020990965,0.0004759339,0.0000024328199,0.0023762595,0.00011428116,0.97883177,0.00016198111,0.00033495954,0.012336816],"study_design_scores_gemma":[0.0033898046,0.00008144909,0.00663885,0.0007225257,0.0003403194,0.000059165075,0.0005638836,0.06252102,0.9161308,0.00022483217,0.008510006,0.0008173402],"about_ca_topic_score_codex":0.000042979278,"about_ca_topic_score_gemma":0.000012364998,"teacher_disagreement_score":0.06270096,"about_ca_system_score_codex":0.00004483235,"about_ca_system_score_gemma":0.000011389554,"threshold_uncertainty_score":0.99991566},"labels":[],"label_agreement":null},{"id":"W2331932049","doi":"10.1021/jo200424q","title":"Pyrrolo[3,2-<i>e</i>][1,4]diazepin-2-one Synthesis: A Head-to-Head Comparison of Soluble versus Insoluble Supports","year":2011,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":15,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research","keywords":"Chemistry; Cleavage (geology); Combinatorial chemistry; Diazepine; Solid-phase synthesis; Ring (chemistry); Organic chemistry; Materials science","score_opus":0.07929494691841707,"score_gpt":0.3138640356554065,"score_spread":0.23456908873698942,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2331932049","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.987212,0.0011613193,0.00007587856,0.0006421724,0.00034679886,0.00007468646,0.00001587068,0.00003713272,0.01043413],"genre_scores_gemma":[0.9980632,0.00020955286,0.0008812657,0.00009679026,0.00037590988,0.0000068851564,0.0000028854722,0.00006130802,0.00030222308],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9973875,0.000085044754,0.0012348414,0.00025065787,0.0005252409,0.0005166668],"domain_scores_gemma":[0.9966858,0.0007933432,0.0012604336,0.0006217574,0.00031594103,0.000322722],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008480994,0.00035543146,0.00094536133,0.00006218005,0.00015630721,0.00001790009,0.0011763871,0.00024718806,0.020497242],"category_scores_gemma":[0.0006530229,0.0002884155,0.00027623016,0.00027661028,0.0002751686,0.00015463129,0.00021267837,0.0006968369,0.000044022516],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0020430037,0.00082121504,0.0026084138,0.000245513,0.00059068564,0.000021589703,0.0028650872,0.000011628187,0.98579854,0.0000026596108,0.0031058528,0.0018857918],"study_design_scores_gemma":[0.0013619809,0.00015413694,0.0011309409,0.00025352908,0.00052430865,0.00014098837,0.0020171434,0.000028219292,0.9917847,0.00006328505,0.0022549385,0.00028583506],"about_ca_topic_score_codex":0.000039834213,"about_ca_topic_score_gemma":0.000018059074,"teacher_disagreement_score":0.02045322,"about_ca_system_score_codex":0.000112359725,"about_ca_system_score_gemma":0.0003063523,"threshold_uncertainty_score":0.9999568},"labels":[],"label_agreement":null},{"id":"W2333884474","doi":"10.1021/jo2021345","title":"Synthesis of Extended, π-Conjugated Isoindolin-1-ones","year":2012,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":31,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Conjugated system; Stereospecificity; Nucleophile; Amide; Chemistry; Combinatorial chemistry; Alkyne; Molecule; Stereochemistry; Organic chemistry; Catalysis; Polymer","score_opus":0.015359235259798048,"score_gpt":0.2571423155878659,"score_spread":0.24178308032806783,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2333884474","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9900621,0.0028102384,0.00003058137,0.000473962,0.00012682262,0.000021454822,0.000013367454,0.000015593674,0.006445875],"genre_scores_gemma":[0.99814373,0.0004770716,0.00016042923,0.000051333467,0.0007884115,0.0000014477121,0.0000010703689,0.00003037724,0.00034612505],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99861515,0.000058905247,0.00065581454,0.000082226834,0.0002857949,0.00030211234],"domain_scores_gemma":[0.9975737,0.0008988732,0.00090263644,0.0003012859,0.00017523528,0.00014826837],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0007742558,0.00019624467,0.00043925407,0.000025105708,0.000082198014,0.000007925782,0.00058790063,0.00014390518,0.016486268],"category_scores_gemma":[0.0006538996,0.00013365108,0.0001841189,0.0001269715,0.00021884944,0.00014075148,0.0000801782,0.00038604927,0.000017754526],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015949468,0.00023376968,0.0016734104,0.00015218346,0.00029677988,0.0000037488703,0.0005492077,0.00000225256,0.9940827,0.0000030232447,0.0011472639,0.001696202],"study_design_scores_gemma":[0.00039768263,0.000010308385,0.0011999066,0.00010872805,0.0003031989,0.00050485844,0.0012055602,0.000007230422,0.9945704,0.000052771644,0.0014999734,0.0001393894],"about_ca_topic_score_codex":0.0000026843632,"about_ca_topic_score_gemma":1.7879658e-7,"teacher_disagreement_score":0.016468514,"about_ca_system_score_codex":0.00004643147,"about_ca_system_score_gemma":0.000103101986,"threshold_uncertainty_score":0.9844128},"labels":[],"label_agreement":null},{"id":"W2404004983","doi":"","title":"Synthesis and antitumor cytotoxicity evaluation of novel pyrrolo[2,1-c][1,4]benzodiazepine imidazole containing polyamide conjugates.","year":2003,"lang":"en","type":"article","venue":"PubMed","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":7,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Cytotoxicity; Imidazole; Chemistry; Conjugate; Cancer cell; Cytotoxic T cell; Polyamide; Structure–activity relationship; Stereochemistry; In vitro; Pyrrole; Biological activity; Cancer; Combinatorial chemistry; Biochemistry; Biology; Organic chemistry","score_opus":0.06048955236647287,"score_gpt":0.277880901145361,"score_spread":0.21739134877888816,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2404004983","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9806766,0.0010434134,0.000047766644,0.00019789506,0.00008974969,0.0004069692,0.00009877318,0.00006134465,0.017377505],"genre_scores_gemma":[0.9981148,0.00008654936,0.00030005383,0.00013075721,0.00006968951,0.0012083293,0.0000082630095,0.000031623305,0.000049929382],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9980334,0.0001449069,0.00049718167,0.00042302322,0.00041867152,0.0004828121],"domain_scores_gemma":[0.99817,0.00081354723,0.00034825463,0.000274573,0.00021783027,0.00017578564],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0019316224,0.00026027378,0.00050586194,0.00012214528,0.0001288315,0.000030724197,0.00017295181,0.000148038,0.0009660849],"category_scores_gemma":[0.0033454825,0.0002603684,0.000099952944,0.00015301099,0.00027780983,0.00018803772,0.000049937895,0.00017142382,0.0000029682092],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00023251247,0.00066724705,0.03783136,0.0002729322,0.000528467,0.000006458975,0.00041381954,0.000205276,0.9098205,0.0014062691,0.00019901249,0.048416156],"study_design_scores_gemma":[0.0013818521,0.000010258348,0.11014472,0.000039302366,0.00023802715,0.000017961476,0.00025495517,0.0012051107,0.8859673,0.00010336053,0.0003778392,0.00025929097],"about_ca_topic_score_codex":0.00004195907,"about_ca_topic_score_gemma":0.000008266939,"teacher_disagreement_score":0.07231336,"about_ca_system_score_codex":0.00007559086,"about_ca_system_score_gemma":0.0000835242,"threshold_uncertainty_score":0.99998486},"labels":[],"label_agreement":null},{"id":"W2410298648","doi":"","title":"SB-277011 GlaxoSmithKline.","year":2001,"lang":"en","type":"article","venue":"PubMed","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":16,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Nucleus accumbens; Pharmacology; Neurochemical; Dopamine; Antagonist; Neuroscience; Psychology; Dopamine receptor; Chemistry; Receptor; Medicine; Internal medicine","score_opus":0.037627711535571845,"score_gpt":0.23919716941874605,"score_spread":0.2015694578831742,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2410298648","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.76905245,0.0004903021,0.000023715897,0.0018605684,0.00016916546,0.0000957542,0.000009467418,0.00015837372,0.2281402],"genre_scores_gemma":[0.9896269,0.00017130467,0.00010357247,0.00068484386,0.00054014573,0.00074811827,0.000008227865,0.00002054979,0.00809635],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9990606,0.000017106242,0.00017582714,0.00023152333,0.00012251723,0.00039246303],"domain_scores_gemma":[0.9994295,0.00013418893,0.000065700624,0.00020243149,0.000030197612,0.0001379838],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00014041783,0.00013248216,0.00016290936,0.000041164512,0.0000755215,0.00002193976,0.00021270089,0.00008584376,0.004028086],"category_scores_gemma":[0.00013089938,0.00012354682,0.000084609346,0.00009975807,0.00007148256,0.000086521744,0.000043502325,0.0001306841,0.00010399795],"study_design_candidate":"design_other","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00011145156,0.00024401417,0.06369062,0.00004259702,0.00016505833,0.000079205754,0.00017397906,0.000006134933,0.006313674,0.00027684204,0.036272693,0.8926237],"study_design_scores_gemma":[0.00069049635,0.00000380549,0.24941538,0.000006476392,0.000035481862,0.000034400582,0.000098552286,0.000063738,0.07544685,0.0004380012,0.6734846,0.0002822068],"about_ca_topic_score_codex":0.000012634114,"about_ca_topic_score_gemma":0.0000029669009,"teacher_disagreement_score":0.89234155,"about_ca_system_score_codex":0.000028611541,"about_ca_system_score_gemma":0.000010358234,"threshold_uncertainty_score":0.9968824},"labels":[],"label_agreement":null},{"id":"W2411943562","doi":"10.1021/acs.orglett.5b01679","title":"γ-Turn Mimicry with Benzodiazepinones and Pyrrolobenzodiazepinones Synthesized from a Common Amino Ketone Intermediate","year":2015,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":33,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Dihedral angle; Ozonolysis; Ketone; Intramolecular force; Aniline; Acylation; Stereochemistry; Ring (chemistry); Amino acid; Olefin fiber; Turn (biochemistry); Medicinal chemistry; Organic chemistry; Molecule; Catalysis; Biochemistry","score_opus":0.016671628509679504,"score_gpt":0.23079248378893585,"score_spread":0.21412085527925634,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2411943562","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9911476,0.0010141804,0.000091065005,0.006435993,0.0002347677,0.00015003941,0.00011978107,0.00026351554,0.00054306735],"genre_scores_gemma":[0.9945564,0.00014214255,0.0006553614,0.0038044134,0.00052419957,0.00005163485,0.00009108493,0.00010837067,0.0000663858],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99764717,0.00014107318,0.0004793005,0.0007511912,0.00036357006,0.00061772275],"domain_scores_gemma":[0.99796605,0.0006689434,0.00032058582,0.00054278364,0.00007044544,0.00043119772],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00024028883,0.0005512632,0.0007753342,0.00012013314,0.00015488768,0.00011272367,0.0004915318,0.00022366554,0.0013923714],"category_scores_gemma":[0.00015459619,0.00046846725,0.00009473586,0.00016980589,0.0005493904,0.00032399016,0.00020260396,0.00043997183,0.0001217288],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0004857318,0.00014093761,0.04244819,0.0000634256,0.0003949153,0.00017790539,0.0022271567,0.000003640759,0.94548804,0.0000136790595,0.0051158573,0.0034405112],"study_design_scores_gemma":[0.004710896,0.00012660811,0.036127757,0.00025252232,0.0004023444,0.00012231036,0.0016449838,0.00023106173,0.95008826,0.00017431834,0.0049707,0.0011482525],"about_ca_topic_score_codex":0.0003243644,"about_ca_topic_score_gemma":0.00011078156,"teacher_disagreement_score":0.006320433,"about_ca_system_score_codex":0.000114458846,"about_ca_system_score_gemma":0.00009089889,"threshold_uncertainty_score":0.9997767},"labels":[],"label_agreement":null},{"id":"W2569553785","doi":"10.1007/s11030-016-9718-3","title":"Convenient access to 5-arylisoindolo[2,1- $${\\varvec{a}}$$ a ]quinolin-11(6a $${\\varvec{H}}$$ H )-ones","year":2017,"lang":"en","type":"article","venue":"Molecular Diversity","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Acadia University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aryl; Lewis acids and bases; Catalysis; Chemistry; Medicinal chemistry; Organic chemistry; Alkyl","score_opus":0.05721680818644301,"score_gpt":0.32217266882373213,"score_spread":0.26495586063728915,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2569553785","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9795212,0.00014425734,0.0005054261,0.0032445206,0.0004420345,0.00023025316,0.00014341588,0.000149964,0.015618916],"genre_scores_gemma":[0.99704593,0.000034583038,0.00030941115,0.0015044372,0.00018258888,0.000029824716,0.000030145544,0.00003448277,0.0008286065],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9975565,0.000078503406,0.00029006205,0.0009820737,0.00046470505,0.0006281575],"domain_scores_gemma":[0.9973919,0.0000916251,0.00032740066,0.0016048993,0.00017198734,0.00041219796],"candidate_categories":["metaepi_narrow","sts","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003371783,0.00039404223,0.0005106891,0.00012801195,0.0017835621,0.00037491843,0.0025792758,0.00023247325,0.0030497771],"category_scores_gemma":[0.0004233648,0.00042298433,0.00031332797,0.00009518361,0.0003308211,0.0005010958,0.0043709916,0.0002553602,0.0003015834],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0006284514,0.00090110203,0.46037215,0.000298373,0.0009653858,0.0014628484,0.0026269513,0.00017578673,0.49284327,0.0013893457,0.02845247,0.009883863],"study_design_scores_gemma":[0.0021224315,0.000056805264,0.16751805,0.0000939999,0.00019877988,0.000019024503,0.00021552782,0.00009965472,0.7855531,0.00045621293,0.0427915,0.00087489554],"about_ca_topic_score_codex":0.0006959852,"about_ca_topic_score_gemma":0.000075914526,"teacher_disagreement_score":0.2928541,"about_ca_system_score_codex":0.00010198402,"about_ca_system_score_gemma":0.00006128651,"threshold_uncertainty_score":0.9998222},"labels":[],"label_agreement":null},{"id":"W2617943271","doi":"10.1007/s00280-008-0848-x","title":"Identification, characterization and potent antitumor activity of ECO-4601, a novel peripheral benzodiazepine receptor ligand","year":2008,"lang":"en","type":"article","venue":"Cancer Chemotherapy and Pharmacology","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":3,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Identification (biology); Benzodiazepine; Ligand (biochemistry); Peripheral; Pharmacology; Chemistry; GABAA receptor; Receptor; Biology; Medicine; Biochemistry; Internal medicine; Botany","score_opus":0.022173343416873204,"score_gpt":0.289562908502084,"score_spread":0.2673895650852108,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2617943271","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99448305,0.0010993341,0.0013080854,0.0020634676,0.00030663123,0.00023504178,0.00040152323,0.000033755805,0.0000690977],"genre_scores_gemma":[0.9864158,0.011235861,0.00022423349,0.0007664206,0.00047741598,0.00019189293,0.00005193812,0.00002895503,0.0006074832],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99900377,0.000026732947,0.00029065096,0.0003783238,0.000077096374,0.00022340292],"domain_scores_gemma":[0.99928087,0.00011339088,0.00029218566,0.000098060475,0.00011979956,0.000095706615],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000115345625,0.00020594355,0.00037866863,0.000057391368,0.00020238645,0.000010949888,0.00010726093,0.00013430609,0.001268133],"category_scores_gemma":[0.000012701537,0.00020885852,0.00006166894,0.00008407495,0.0003609273,0.0001544008,0.000023656972,0.00012034355,6.5387275e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0005615609,0.00022049723,0.004221883,0.00023722123,0.00019993768,8.089892e-7,0.0009948411,0.0000046740897,0.9745975,0.000023023726,0.00074706913,0.018190954],"study_design_scores_gemma":[0.002703594,0.000052286337,0.019675227,0.00002173739,0.000057267447,0.000015570253,0.00002379568,0.00086270913,0.95602053,0.000012502931,0.020348718,0.00020603382],"about_ca_topic_score_codex":0.00001611991,"about_ca_topic_score_gemma":0.000001601107,"teacher_disagreement_score":0.019601649,"about_ca_system_score_codex":0.00003468038,"about_ca_system_score_gemma":0.0000763815,"threshold_uncertainty_score":0.9996448},"labels":[],"label_agreement":null},{"id":"W2788600770","doi":"10.1016/j.heliyon.2018.e00539","title":"Synthesis and biological activity of fused tetracyclic Pyrrolo[2,1-c][1,4]benzodiazepines","year":2018,"lang":"en","type":"article","venue":"Heliyon","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Research and Development Corporation of Newfoundland and Labrador","keywords":"Electrophile; Stereochemistry; Cytotoxicity; Chemistry; Imine; Combinatorial chemistry; Guanine; Structure–activity relationship; Lead compound; Computational biology; Biochemistry; Biology; Gene; In vitro; Nucleotide","score_opus":0.03878416941980585,"score_gpt":0.2937522391615638,"score_spread":0.25496806974175795,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2788600770","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.99019474,0.0013185099,0.000017669765,0.00041339148,0.000093042574,0.00006163996,0.000052841016,0.000090409376,0.007757745],"genre_scores_gemma":[0.9974316,0.0016185974,0.0003447843,0.00011435782,0.00033411055,0.000033431177,0.000002381949,0.00001920629,0.00010157938],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884844,0.00008191343,0.0002591027,0.00037917323,0.00013228704,0.0002990679],"domain_scores_gemma":[0.99857396,0.000800798,0.0001766215,0.00026194815,0.000078714205,0.0001079445],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00021412814,0.00021670494,0.0004153058,0.0000829315,0.00012564477,0.000014617644,0.0001985571,0.00023286718,0.0035614774],"category_scores_gemma":[0.00053954247,0.00017921999,0.00009512693,0.00012671402,0.0006604036,0.000102552985,0.00009783312,0.00015227306,0.00004434412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015667918,0.00017040399,0.020037504,0.0002205769,0.000074620635,0.000003597234,0.00019063616,1.6548921e-7,0.94364756,0.000062135034,0.000119365315,0.035316776],"study_design_scores_gemma":[0.00028488846,0.000079887206,0.093199074,0.00014124913,0.00003384041,0.000008441846,0.00006960653,0.00005202334,0.90249497,0.00007893512,0.0033666187,0.00019045967],"about_ca_topic_score_codex":0.00001550091,"about_ca_topic_score_gemma":0.00000716247,"teacher_disagreement_score":0.07316157,"about_ca_system_score_codex":0.000014810195,"about_ca_system_score_gemma":0.000022265744,"threshold_uncertainty_score":0.9973494},"labels":[],"label_agreement":null},{"id":"W2949986409","doi":"10.1002/chin.201623129","title":"ChemInform Abstract: Facile Synthesis of 3‐Substituted Isoindolinones.","year":2016,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"Acadia University","funders":"","keywords":"Nova scotia; Humanities; Library science; Chemistry; Philosophy; Computer science; History; Archaeology","score_opus":0.02194280715908809,"score_gpt":0.25618045882000046,"score_spread":0.23423765166091237,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2949986409","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.16679633,0.00011719758,4.7397143e-7,0.00021140638,0.00008387877,0.000064036634,0.00018556908,0.00011154689,0.8324296],"genre_scores_gemma":[0.98213375,0.00017492348,0.000041502848,0.00004882077,0.0001662682,0.0000803483,0.000019853436,0.000026079602,0.01730848],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99841875,6.416626e-8,0.00062485854,0.0002612516,0.00027278613,0.00042230895],"domain_scores_gemma":[0.9982571,0.0006303293,0.0003866517,0.00043685184,0.00012679302,0.00016228814],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001611096,0.0002950753,0.0004563192,0.000077863595,0.000071503746,0.000013199818,0.00045650962,0.00026126008,0.03579647],"category_scores_gemma":[0.0005136387,0.00021070073,0.00021809126,0.00011526792,0.00033276575,0.00034975453,0.00009297441,0.00012840724,0.00025957066],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000060313898,0.00006512637,0.00019650227,0.00020039735,0.00009557822,0.0000036058852,0.00019084118,4.169073e-8,0.40718675,0.00008221156,0.010330568,0.5815881],"study_design_scores_gemma":[0.000574871,0.000005294027,0.001032846,0.0001996956,0.000039588802,0.00001106585,0.00017494272,0.0000018214445,0.92776847,0.000052464908,0.06984925,0.0002897107],"about_ca_topic_score_codex":0.000014369662,"about_ca_topic_score_gemma":0.0000015074868,"teacher_disagreement_score":0.8153374,"about_ca_system_score_codex":0.000080780635,"about_ca_system_score_gemma":0.000104338484,"threshold_uncertainty_score":0.96508497},"labels":[],"label_agreement":null},{"id":"W2950035201","doi":"10.1002/chin.201608141","title":"ChemInform Abstract: Dearomative Indole Bisfunctionalization via a Diastereoselective Palladium‐Catalyzed Arylcyanation.","year":2016,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Palladium; Indole test; Catalysis; Medicinal chemistry; Combinatorial chemistry; Stereochemistry; Organic chemistry","score_opus":0.016110121880226487,"score_gpt":0.24829180386703828,"score_spread":0.2321816819868118,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950035201","genre_codex":"other","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.15936926,0.00011591269,0.000039998497,0.00048338514,0.00015184956,0.00018395702,0.00009935456,0.00024004932,0.83931625],"genre_scores_gemma":[0.9816486,0.000066508546,0.000044461834,0.00017213599,0.0003114016,0.00016066089,0.00020730268,0.000036593043,0.017352322],"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9984223,2.1061858e-7,0.0004998285,0.0003426844,0.00033076384,0.00040420052],"domain_scores_gemma":[0.99851334,0.00042770852,0.00038823063,0.00025368293,0.0002490293,0.00016798748],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016257218,0.00032417467,0.00030483486,0.0001222298,0.0001670374,0.00003840993,0.0002819334,0.00023944682,0.021861596],"category_scores_gemma":[0.0003075093,0.00024517614,0.00014452572,0.00022631932,0.000182073,0.0007274453,0.000078452525,0.0001480275,0.0003805227],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00013826133,0.00010788035,0.00058562786,0.00010034012,0.00023714839,0.0000032524379,0.0012911428,2.653632e-7,0.38913476,0.0001705166,0.012334227,0.5958966],"study_design_scores_gemma":[0.0013202353,0.000013762914,0.0064260424,0.00010330496,0.000036186262,0.000016719901,0.00025652925,0.000022194583,0.967915,0.0004336899,0.023081027,0.00037532402],"about_ca_topic_score_codex":0.000016379074,"about_ca_topic_score_gemma":0.000007198958,"teacher_disagreement_score":0.82227933,"about_ca_system_score_codex":0.00029052232,"about_ca_system_score_gemma":0.00012571576,"threshold_uncertainty_score":0.99979925},"labels":[],"label_agreement":null},{"id":"W2950043423","doi":"10.1002/chin.201102185","title":"ChemInform Abstract: Synthesis of Dibenzo[b,f][1,4]oxazepin‐11(10H)‐ones via Intramolecular Cyclocarbonylation Reactions Using PdI<sub>2</sub>/Cytop 292 as the Catalytic System.","year":2010,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Intramolecular force; Political science; Stereochemistry","score_opus":0.012007114070142585,"score_gpt":0.24553619657458864,"score_spread":0.23352908250444604,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950043423","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7635608,0.0000960392,0.0000029646328,0.00018714165,0.00030159624,0.00023821887,0.000052739466,0.00015847682,0.23540206],"genre_scores_gemma":[0.9987393,0.00004386308,0.00006633952,0.0000850976,0.00044505796,0.00014003183,0.000085200234,0.00007229103,0.0003228205],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99728817,9.4452963e-7,0.0011284337,0.00044616128,0.000528407,0.00060789136],"domain_scores_gemma":[0.9967643,0.0007708161,0.0009858105,0.0009516986,0.0002596063,0.00026778804],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00052063004,0.00053266983,0.0006351568,0.00014947576,0.0003746926,0.000080956655,0.0006760139,0.00054432306,0.0009141335],"category_scores_gemma":[0.0008572393,0.00045384953,0.00036611778,0.00033617404,0.00051282934,0.0004681883,0.00015323862,0.00070364366,0.000069361595],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000045017954,0.00011289452,0.00007273913,0.0006192924,0.00024474607,0.000009812745,0.0006365922,0.000008925692,0.9268317,0.00025150465,0.0004318745,0.070734866],"study_design_scores_gemma":[0.00037079264,0.000010082443,0.0005832537,0.000246012,0.00032579104,0.00014867434,0.0012471607,0.0010524406,0.9904828,0.00007600665,0.004967084,0.0004898813],"about_ca_topic_score_codex":0.00031254278,"about_ca_topic_score_gemma":0.000030262398,"teacher_disagreement_score":0.23517855,"about_ca_system_score_codex":0.00020239629,"about_ca_system_score_gemma":0.00026150292,"threshold_uncertainty_score":0.99999917},"labels":[],"label_agreement":null},{"id":"W2950800750","doi":"10.1002/chin.200404224","title":"Design, Synthesis and in vitro Cytotoxicity Studies of Novel Pyrrolo[2,1][1,4]benzodiazepine‐glycosylated Pyrrole and Imidazole Polyamide Conjugates.","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Pyrrole; Chemistry; Imidazole; Citation; Conjugate; Information retrieval; Stereochemistry; Combinatorial chemistry; Computer science; Library science; Organic chemistry; Mathematics","score_opus":0.03947986285479256,"score_gpt":0.2832873571545036,"score_spread":0.24380749429971105,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2950800750","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9914837,0.0026028506,0.0000125467295,0.0003417829,0.000029069135,0.00017727753,0.00007967702,0.00006729635,0.005205782],"genre_scores_gemma":[0.99763423,0.0010410579,0.00091723836,0.00015294409,0.000040602616,0.00009199837,0.000010255298,0.000030282152,0.00008139216],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99839675,0.000002508272,0.00061098905,0.00038006424,0.00017695392,0.00043274328],"domain_scores_gemma":[0.99838525,0.00085874205,0.00028305696,0.00023675308,0.000095497024,0.00014069611],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00033754867,0.00036034686,0.00074296584,0.00014908155,0.00009966878,0.00002194794,0.00019967249,0.00023126585,0.0001335268],"category_scores_gemma":[0.0006850111,0.00033978,0.00007046305,0.0001874824,0.0006009358,0.00025298554,0.00017307483,0.00024321853,0.0000031068573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00041640553,0.0001735767,0.00023336991,0.00036800586,0.00019040974,0.000010242655,0.0015110326,0.000041929296,0.9901113,0.000018209628,0.000057385536,0.006868136],"study_design_scores_gemma":[0.001778847,0.000025638388,0.0010543297,0.00025190436,0.00006741634,0.000028834842,0.0011127809,0.00024852963,0.9948642,0.00014594602,0.000083057654,0.0003385063],"about_ca_topic_score_codex":0.000060887087,"about_ca_topic_score_gemma":0.000008085099,"teacher_disagreement_score":0.0065296297,"about_ca_system_score_codex":0.00010398384,"about_ca_system_score_gemma":0.00008067458,"threshold_uncertainty_score":0.9999054},"labels":[],"label_agreement":null},{"id":"W2951246593","doi":"10.1016/j.tetlet.2008.10.083","title":"Novel synthesis of 2,2-dialkyl-3-dialkylamino-2,3-dihydro-1H-naphtho[2,1-b]pyrans","year":2008,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":29,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Dalhousie University; Acadia University","funders":"Natural Sciences and Engineering Research Council of Canada; Acadia University","keywords":"Chemistry; Enamine; Aldol reaction; Amine gas treating; Formaldehyde; Aldol condensation; Quinone methide; Mannich reaction; Catalysis; Base (topology); Organic chemistry; Medicinal chemistry; Stereochemistry; Quinone","score_opus":0.02648427443576583,"score_gpt":0.24246348642649546,"score_spread":0.2159792119907296,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951246593","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9814616,0.0003192123,0.0004104247,0.002171272,0.0002887503,0.00012728151,0.00016482956,0.00021260112,0.014844055],"genre_scores_gemma":[0.99568826,0.0001486718,0.0019464921,0.0011789682,0.00045646398,0.00007492321,0.00002292278,0.000082782324,0.00040052636],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997438,0.00006181436,0.0007226789,0.00062278856,0.0004841876,0.0006705049],"domain_scores_gemma":[0.9977617,0.00100223,0.00035308846,0.0006188485,0.00006534909,0.00019875335],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002405476,0.0004692343,0.000749838,0.00022711634,0.00024063748,0.00001537425,0.0006622838,0.00024546168,0.0040444024],"category_scores_gemma":[0.00028320844,0.0004775682,0.0004008558,0.0002742473,0.0007828785,0.0002198049,0.00008155544,0.00037200365,0.000109473665],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008500794,0.00034502623,0.0054398132,0.00014685164,0.00023705103,0.00006669508,0.0006841441,0.00010237125,0.98175347,0.00006042175,0.0066108396,0.0044683064],"study_design_scores_gemma":[0.00094665814,0.000028836954,0.012505007,0.0000991882,0.00011022919,0.00012831559,0.00012819924,0.00018929987,0.9768971,0.0000146276325,0.008381827,0.0005707191],"about_ca_topic_score_codex":0.00016353981,"about_ca_topic_score_gemma":0.0000064152237,"teacher_disagreement_score":0.014443529,"about_ca_system_score_codex":0.00009374015,"about_ca_system_score_gemma":0.00007837907,"threshold_uncertainty_score":0.9997676},"labels":[],"label_agreement":null},{"id":"W2951351778","doi":"10.1002/chin.200828114","title":"ChemInform Abstract: Efficient Preparation of the Isoindoline Framework via a Six Component, Tandem Double A<sup>3</sup>‐Coupling and [2 + 2 + 2] Cycloaddition Reaction.","year":2008,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Chemistry; Isoindoline; Tandem; Component (thermodynamics); Combinatorial chemistry; Coupling (piping); Cycloaddition; Coupling reaction; Organic chemistry; Catalysis","score_opus":0.02136886502717081,"score_gpt":0.2723323208935866,"score_spread":0.2509634558664158,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951351778","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8637115,0.0001635089,0.000003872853,0.00012667367,0.000071892486,0.00017657458,0.000028870914,0.00006572966,0.13565142],"genre_scores_gemma":[0.99783015,0.0001333034,0.00006986232,0.00007035794,0.00026125897,0.000056243643,0.00010312379,0.00001986044,0.0014558551],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99859077,1.6094495e-7,0.0005690481,0.00025256505,0.00031015807,0.000277299],"domain_scores_gemma":[0.9987032,0.0002608023,0.00047657397,0.0003436102,0.00011792768,0.000097916134],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00016431756,0.00025028875,0.00031322078,0.000047727288,0.00034759648,0.0000185486,0.00021920708,0.0002784872,0.0013615664],"category_scores_gemma":[0.00010128864,0.00020497269,0.00014131829,0.00015710763,0.00028672462,0.00020241301,0.00009441059,0.00036725207,0.000015468178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0015226948,0.0012648074,0.003924692,0.0012798252,0.00061734306,0.000013210082,0.020878388,0.0025484974,0.882025,0.0004310613,0.0268901,0.058604352],"study_design_scores_gemma":[0.0010048595,0.000015555644,0.0041509415,0.0001710779,0.000048882503,0.00007126588,0.0004423929,0.0055737663,0.9812188,0.00006102089,0.0069933296,0.00024807503],"about_ca_topic_score_codex":0.000026623433,"about_ca_topic_score_gemma":0.0000010353303,"teacher_disagreement_score":0.13419557,"about_ca_system_score_codex":0.00009737013,"about_ca_system_score_gemma":0.000065679546,"threshold_uncertainty_score":0.9995513},"labels":[],"label_agreement":null},{"id":"W2951361034","doi":"10.1002/chin.201225117","title":"ChemInform Abstract: Development of a Copper(II)‐Catalyzed Three‐Component Tandem Synthesis of Isoindolinone Derivatives.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Chemistry; Tandem; Catalysis; Combinatorial chemistry; Component (thermodynamics); Copper; Organic chemistry; Aerospace engineering","score_opus":0.0313774836823643,"score_gpt":0.2694596172574487,"score_spread":0.2380821335750844,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951361034","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6572701,0.0004816068,0.000001120029,0.00004363404,0.00006721628,0.00011854989,0.000041373005,0.000049198825,0.34192726],"genre_scores_gemma":[0.99748695,0.00005932517,0.001053311,0.000030004272,0.00014703648,0.00011699166,0.00008140036,0.000036820915,0.0009881677],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974552,2.1186077e-7,0.0012277461,0.00024117547,0.00044509058,0.0006306146],"domain_scores_gemma":[0.99777615,0.0004601679,0.0009199081,0.0004279736,0.00016602052,0.00024978947],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00045374187,0.0004156435,0.0008123854,0.0001152782,0.000168069,0.000008892127,0.0005110037,0.00028166,0.0062030843],"category_scores_gemma":[0.0002902492,0.00038396844,0.00023634058,0.0001862104,0.00034029695,0.0003971402,0.0002794745,0.00023602517,0.000034388533],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00012087978,0.00057035935,0.0021042826,0.00074970024,0.00044481948,8.515669e-7,0.0059741423,2.0972531e-7,0.6695955,0.00007044598,0.0021412577,0.3182276],"study_design_scores_gemma":[0.00067766703,0.000008979136,0.014666422,0.00025621607,0.00007718434,0.000008744558,0.000986114,0.0000061081773,0.9688636,0.000014140202,0.01403904,0.00039576832],"about_ca_topic_score_codex":0.000013207021,"about_ca_topic_score_gemma":0.0000028988745,"teacher_disagreement_score":0.34093907,"about_ca_system_score_codex":0.00013727072,"about_ca_system_score_gemma":0.00021071667,"threshold_uncertainty_score":0.99986124},"labels":[],"label_agreement":null},{"id":"W2951635669","doi":"10.1002/chin.200916105","title":"ChemInform Abstract: Syntheses of Substituted 3‐Methyleneisoindolin‐1‐ones by a Palladium‐Catalyzed Sonogashira Coupling—Carbonylation—Hydroamination Sequence in Phosphonium Salt Based Ionic Liquids.","year":2009,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Sonogashira coupling; Carbonylation; Phosphonium; Hydroamination; Palladium; Phosphonium salt; Sequence (biology); Salt (chemistry); Catalysis; Combinatorial chemistry; Coupling (piping); Ionic liquid; Organic chemistry; Carbon monoxide","score_opus":0.024262680092524934,"score_gpt":0.27407599793399673,"score_spread":0.2498133178414718,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2951635669","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.87725693,0.00082217215,0.0000027848757,0.00045642487,0.00008868848,0.00024983173,0.0001354388,0.00015460605,0.12083311],"genre_scores_gemma":[0.99805874,0.00025939403,0.00010479645,0.00013670135,0.000088491724,0.00007533202,0.00054619287,0.00003161055,0.00069875503],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9974352,4.0666288e-7,0.0010866444,0.00045484758,0.0004365467,0.0005863576],"domain_scores_gemma":[0.9977622,0.0006629498,0.00071830756,0.000467088,0.00021089838,0.00017856841],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00044823968,0.00047054217,0.0006569175,0.00020588099,0.00010769044,0.000047536112,0.00054144993,0.00044861552,0.0019039362],"category_scores_gemma":[0.0006612595,0.00048952625,0.00020232296,0.00044430429,0.0002647245,0.00053487485,0.000042060485,0.0003943888,0.00002204326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00036849495,0.00044374296,0.00036866916,0.0004208474,0.00007345307,0.000012336018,0.00091707165,0.00012141951,0.90320426,0.0001094539,0.0011923707,0.09276786],"study_design_scores_gemma":[0.0012451888,0.000029478995,0.0020265775,0.00037934945,0.000045669676,0.0000057021903,0.00023996545,0.0035183777,0.9904433,0.00006771349,0.001502069,0.00049662805],"about_ca_topic_score_codex":0.000109209956,"about_ca_topic_score_gemma":0.000015401842,"teacher_disagreement_score":0.12080178,"about_ca_system_score_codex":0.00031020714,"about_ca_system_score_gemma":0.0003227908,"threshold_uncertainty_score":0.9997556},"labels":[],"label_agreement":null},{"id":"W2952251103","doi":"10.1002/chin.200929114","title":"ChemInform Abstract: Preparation of 1‐Aryl‐Substituted Isoindoline Derivatives by Sequential Morita—Baylis—Hillman and Intramolecular Diels—Alder Reactions.","year":2009,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Chemistry; Isoindoline; Intramolecular force; Aryl; Baylis–Hillman reaction; Combinatorial chemistry; Organic chemistry; Medicinal chemistry; Adduct; Alkyl","score_opus":0.014878930582840386,"score_gpt":0.28624789792099053,"score_spread":0.27136896733815014,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952251103","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.680108,0.0006336757,0.0000068203285,0.00038990323,0.0000689943,0.0001793688,0.00008110329,0.00011419362,0.31841794],"genre_scores_gemma":[0.99652183,0.00029995726,0.00012699695,0.0001616605,0.00016276984,0.000030552597,0.00042796892,0.00001894911,0.0022493026],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99842817,1.8715181e-7,0.000677611,0.0003173058,0.00024728957,0.00032945353],"domain_scores_gemma":[0.9988775,0.00010466148,0.00042817972,0.0002993186,0.00014035907,0.0001499601],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000139862,0.0003235675,0.00039721414,0.000076135926,0.00013182082,0.000041880987,0.00021427625,0.00026954507,0.0018376076],"category_scores_gemma":[0.00017093816,0.0003238246,0.00011425922,0.00015016868,0.00026098083,0.0005856058,0.00004807052,0.00026871273,0.000007863817],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00015533966,0.0001779084,0.000057399746,0.00019071555,0.00012856138,0.000004116209,0.0011932357,0.0000016517669,0.9021528,0.00017239779,0.012046979,0.0837189],"study_design_scores_gemma":[0.00084169453,0.00004433352,0.001151138,0.00008388643,0.000049332783,0.00002257609,0.00035822857,0.00007106049,0.9754712,0.00017687818,0.021403698,0.00032596375],"about_ca_topic_score_codex":0.000028843295,"about_ca_topic_score_gemma":0.0000020005732,"teacher_disagreement_score":0.31641382,"about_ca_system_score_codex":0.000064378044,"about_ca_system_score_gemma":0.000065723754,"threshold_uncertainty_score":0.9999214},"labels":[],"label_agreement":null},{"id":"W2952627848","doi":"10.1139/v05-111","title":"Synthesis of <i>N</i>-substituted isoindolinones via a palladium catalysed three-component carbonylation amination Michael addition cascade","year":2005,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":22,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Palladium; Carbonylation; Amination; Intramolecular force; Amide; Michael reaction; Aryl; Iodide; Cascade reaction; Yield (engineering); Cascade; Ring (chemistry); Amine gas treating; Organic chemistry; Medicinal chemistry; Combinatorial chemistry; Catalysis; Alkyl; Carbon monoxide","score_opus":0.011909570066749836,"score_gpt":0.22347002941545194,"score_spread":0.2115604593487021,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952627848","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9948138,0.0009851734,0.000183026,0.0007737353,0.0001098052,0.00004817361,0.00017015931,0.000011873975,0.002904237],"genre_scores_gemma":[0.9986111,0.000037075766,0.00041519816,0.000047612222,0.0007133844,0.000009957186,0.00007973889,0.00002574997,0.000060218215],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99850065,0.000026221689,0.0007295226,0.00018927497,0.0002512021,0.00030315216],"domain_scores_gemma":[0.99800825,0.00021901137,0.0008207324,0.00020531355,0.0003268998,0.00041978806],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00023227045,0.00022544949,0.0004201601,0.00014838968,0.000110600726,0.00002240715,0.00031730672,0.00024307435,0.002307172],"category_scores_gemma":[0.00026470757,0.00023842658,0.00020957437,0.00014349472,0.00019496908,0.0002124893,0.000010475144,0.00029859,0.0000061088376],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000053262986,0.000056156085,0.001700812,0.00016279455,0.00018455103,0.000040606254,0.00040834953,0.00031034983,0.9865606,0.0000029393427,0.0006147153,0.009904896],"study_design_scores_gemma":[0.00054374227,0.000007589173,0.0038243476,0.00021886949,0.00013906739,0.00018924812,0.0001528646,0.0009824741,0.99102396,0.00004918204,0.002648281,0.00022035463],"about_ca_topic_score_codex":0.0010886836,"about_ca_topic_score_gemma":0.0021026346,"teacher_disagreement_score":0.009684541,"about_ca_system_score_codex":0.00030081498,"about_ca_system_score_gemma":0.00064032216,"threshold_uncertainty_score":0.99860483},"labels":[],"label_agreement":null},{"id":"W2952894768","doi":"10.1002/chin.200432220","title":"Synthesis and Antiviral Activity of Novel Fluorinated 2′,3′‐Dideoxynucleosides.","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Combinatorial chemistry","score_opus":0.021645021478045007,"score_gpt":0.2619624693471081,"score_spread":0.2403174478690631,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2952894768","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8424682,0.00006605303,0.000003952909,0.00016306173,0.000026675663,0.000036550493,0.000037658436,0.000050575793,0.15714724],"genre_scores_gemma":[0.9991455,0.00006221401,0.00030323156,0.00003408149,0.000048783895,0.00001766274,0.0000038767225,0.00001628213,0.00036834995],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99924296,3.2818846e-7,0.00021546887,0.00019493778,0.00012560675,0.00022067629],"domain_scores_gemma":[0.9993388,0.00019328648,0.000162779,0.00018757515,0.000047813985,0.00006972119],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009741692,0.0001757988,0.0003007039,0.00004672497,0.00006246992,0.000013206418,0.00015083136,0.00013788864,0.00043970748],"category_scores_gemma":[0.00020350932,0.00016776768,0.00007972065,0.000092672264,0.00023795526,0.00021541103,0.00008231026,0.00013395427,0.000006134009],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000051709314,0.00015544654,0.00028800318,0.00016781384,0.00007385638,0.0000024127587,0.00028139938,9.3925274e-7,0.87370956,0.00019451449,0.00012958181,0.12494474],"study_design_scores_gemma":[0.00074567855,0.000011950473,0.0029641308,0.00008828792,0.000038611,0.000009903147,0.000113863076,0.000034580687,0.99458057,0.00006114139,0.00116944,0.00018185253],"about_ca_topic_score_codex":0.000049732575,"about_ca_topic_score_gemma":0.0000018787823,"teacher_disagreement_score":0.1567789,"about_ca_system_score_codex":0.000042706666,"about_ca_system_score_gemma":0.000048424987,"threshold_uncertainty_score":0.68413675},"labels":[],"label_agreement":null},{"id":"W2953018910","doi":"10.1002/chin.200452145","title":"Synthesis of a Novel Tetrahydroisoquinolino[2,1‐c][1,4]benzodiazepine Ring System with DNA Recognition Potential.","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Benzodiazepine; Ring (chemistry); Stereochemistry; Combinatorial chemistry; DNA; Organic chemistry; Biochemistry","score_opus":0.01861377017674777,"score_gpt":0.230057656324236,"score_spread":0.2114438861474882,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953018910","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.741614,0.00012407952,0.0001619699,0.000104917075,0.00007637596,0.00013663483,0.00015677816,0.00021212093,0.25741312],"genre_scores_gemma":[0.9978958,0.000037128255,0.0014024704,0.000038835904,0.00019868895,0.00010836844,0.000061773826,0.000045923854,0.0002110529],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9983716,8.149104e-7,0.0005614941,0.00034058222,0.00031317887,0.00041234706],"domain_scores_gemma":[0.99878764,0.000134829,0.000419009,0.00035266537,0.00015922132,0.00014661711],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00015433657,0.00032488102,0.000504905,0.0001255114,0.00011539352,0.000025740972,0.00030800316,0.00021175641,0.000533683],"category_scores_gemma":[0.000111133195,0.00028983713,0.00016510609,0.00021107911,0.00019442961,0.000269357,0.0000622743,0.00020808955,0.000036129684],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00027410404,0.00047492277,0.000088929395,0.0020686726,0.00044450822,0.000034049946,0.0006641845,0.00018145857,0.9088719,0.0002334653,0.00012876849,0.08653504],"study_design_scores_gemma":[0.0016789074,0.00004041499,0.00022843013,0.001059415,0.00015466912,0.00015309705,0.001205313,0.00018369306,0.9946483,0.000018291892,0.00025594485,0.00037351903],"about_ca_topic_score_codex":0.000069503105,"about_ca_topic_score_gemma":0.000005069548,"teacher_disagreement_score":0.25720206,"about_ca_system_score_codex":0.00017658417,"about_ca_system_score_gemma":0.0001107152,"threshold_uncertainty_score":0.99995536},"labels":[],"label_agreement":null},{"id":"W2953143506","doi":"10.1016/j.tetlet.2009.09.075","title":"One-pot construction of isoindolo[2,1-a]quinoline system","year":2009,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Steacie Institute for Molecular Sciences; University of Ottawa","funders":"University of Ottawa; Genomic Health","keywords":"Chemistry; Quinoline; Tandem; Condensation; Organic chemistry; Condensation reaction; Combinatorial chemistry; Catalysis","score_opus":0.017199548555080695,"score_gpt":0.24419474446041556,"score_spread":0.22699519590533487,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W2953143506","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98528993,0.00019809138,0.00021696859,0.0032453735,0.00017329822,0.00006589634,0.00002215825,0.00017162971,0.010616625],"genre_scores_gemma":[0.99686766,0.000024284609,0.0019067806,0.000819345,0.00029372462,0.00000605396,0.00001639354,0.000014449214,0.00005133104],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99884635,0.00003544637,0.00039032238,0.00026276158,0.00019596406,0.0002691467],"domain_scores_gemma":[0.99930984,0.0001003637,0.00022780265,0.00025373028,0.00003753855,0.00007069931],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000113903596,0.00017294471,0.0003487171,0.000103039165,0.0000636717,0.000011439296,0.00020745985,0.00010988003,0.0007011828],"category_scores_gemma":[0.000028637543,0.0001869207,0.00012004351,0.0001180354,0.0001851538,0.000100781435,0.000014833746,0.00018190013,0.00003204799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00006158621,0.00008549271,0.0014578738,0.00014984433,0.000073766125,0.000007619867,0.00015213732,0.000027546645,0.974811,0.0007390061,0.0013456453,0.021088464],"study_design_scores_gemma":[0.0009145891,0.0000614065,0.011318613,0.00016760225,0.0000700267,0.000044099277,0.00036753094,0.00016376004,0.9844674,0.000057976373,0.0021001478,0.00026687048],"about_ca_topic_score_codex":0.0000099607805,"about_ca_topic_score_gemma":4.808901e-7,"teacher_disagreement_score":0.020821594,"about_ca_system_score_codex":0.00007862901,"about_ca_system_score_gemma":0.000018750065,"threshold_uncertainty_score":0.76774603},"labels":[],"label_agreement":null},{"id":"W3082375605","doi":"10.1021/acsomega.0c02282","title":"Accessing the Ene–Imine Motif in 1<i>H</i>-Isoindole, Thienopyrrole, and Thienopyridine Building Blocks","year":2020,"lang":"en","type":"article","venue":"ACS Omega","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":5,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation","keywords":"Isoindole; Imine; Ene reaction; Chemistry; Thienopyridine; Combinatorial chemistry; Nucleophilic addition; Nucleophile; Stereochemistry; Medicinal chemistry; Catalysis; Organic chemistry; Biochemistry","score_opus":0.030128472995012978,"score_gpt":0.27705123027781264,"score_spread":0.24692275728279967,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3082375605","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.98248327,0.0024644095,0.000044486755,0.008911122,0.00006332316,0.00008808704,0.000015073248,0.000088384586,0.0058418172],"genre_scores_gemma":[0.9961485,0.00030150334,0.0004922437,0.002556512,0.0003549509,0.00002021062,0.0000076018214,0.000033554075,0.00008487411],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9985953,0.000052911604,0.00033944374,0.00043786003,0.00019491783,0.0003795622],"domain_scores_gemma":[0.9990153,0.00043791145,0.00014861321,0.00022875765,0.000034146455,0.00013529469],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00025453643,0.0002500772,0.00032672373,0.000071321374,0.00024598534,0.00011312515,0.0004755703,0.00013271479,0.00017221071],"category_scores_gemma":[0.00019645371,0.0001908581,0.000053326723,0.00036275535,0.00016556784,0.000240215,0.00029054095,0.00047044217,0.0000066595503],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00010029432,0.00007617051,0.012093106,0.0001034676,0.00007397991,0.00004469776,0.003120299,0.00016912626,0.9549834,0.00014217812,0.001788346,0.027304914],"study_design_scores_gemma":[0.0020730824,0.0000644093,0.01195771,0.00014917567,0.00008800839,0.000037448237,0.0012163373,0.0058252146,0.9186524,0.0005102396,0.058816634,0.0006093445],"about_ca_topic_score_codex":0.000056959656,"about_ca_topic_score_gemma":0.000009568917,"teacher_disagreement_score":0.05702829,"about_ca_system_score_codex":0.000020772943,"about_ca_system_score_gemma":0.0000293581,"threshold_uncertainty_score":0.7782967},"labels":[],"label_agreement":null},{"id":"W3095811344","doi":"10.1182/blood-2020-137451","title":"Preliminary Results of a Phase 2 Study of Camidanlumab Tesirine (Cami), a Novel Pyrrolobenzodiazepine-Based Antibody-Drug Conjugate, in Patients with Relapsed or Refractory Hodgkin Lymphoma","year":2020,"lang":"en","type":"article","venue":"Blood","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Medicine; Brentuximab vedotin; Internal medicine; Refractory (planetary science); Oncology; Gastroenterology; Lymphoma; Surgery; Hodgkin lymphoma; Biology","score_opus":0.021129650880068202,"score_gpt":0.2759776509396197,"score_spread":0.2548480000595515,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3095811344","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9977636,0.00010635342,0.000007552548,0.00015035602,0.000030158362,0.00067297305,0.0007961901,0.00007467132,0.00039814942],"genre_scores_gemma":[0.9989544,0.000010055375,0.00046109353,0.00013114024,0.000055631357,0.00006472435,0.00022658215,0.00006473215,0.000031642943],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99715143,0.00013628363,0.0011365034,0.0007047151,0.00048735965,0.00038373345],"domain_scores_gemma":[0.9975492,0.0005912172,0.00091024226,0.0005336023,0.00023953944,0.00017620783],"candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00023397959,0.0004262389,0.00093981344,0.00016408208,0.00005654933,0.000010735342,0.00046564592,0.00015392063,0.0002031366],"category_scores_gemma":[0.0005918359,0.000349286,0.00010128625,0.00051573577,0.00020062044,0.00014722331,0.00011558118,0.00023937579,0.0000030088468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.109097905,0.12826912,0.23676959,0.0013086487,0.0010426642,0.00027723817,0.0071996707,0.00025007123,0.5131116,0.0000027703472,0.00038735894,0.0022833443],"study_design_scores_gemma":[0.2597528,0.01779665,0.23685011,0.00053550693,0.00057497725,0.0000036647787,0.0014647304,0.0013539954,0.480744,0.0000013771865,0.00023992927,0.00068222656],"about_ca_topic_score_codex":0.00019793799,"about_ca_topic_score_gemma":0.00003835524,"teacher_disagreement_score":0.15065491,"about_ca_system_score_codex":0.00003325431,"about_ca_system_score_gemma":0.000267348,"threshold_uncertainty_score":0.99989593},"labels":[],"label_agreement":null},{"id":"W3198414766","doi":"10.1115/1.4052336","title":"Exact Path Synthesis of RCCC Linkages for a Maximum of Nine Prescribed Positions","year":2021,"lang":"en","type":"article","venue":"Journal of Mechanisms and Robotics","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Path (computing); Mathematics; Control theory (sociology); Computer science; Artificial intelligence; Control (management); Computer network","score_opus":0.018367905371398346,"score_gpt":0.26542076336504405,"score_spread":0.2470528579936457,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198414766","genre_codex":"methods","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.4460766,0.011598746,0.5209845,0.015804274,0.0013627665,0.00041716764,0.0011469233,0.000043189888,0.0025658922],"genre_scores_gemma":[0.7460943,0.0013234576,0.251882,0.00007209957,0.00028657774,0.000005059539,0.0000073255073,0.000025743842,0.00030343016],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99902666,0.000044283643,0.00053194934,0.00010600936,0.00015996868,0.00013110817],"domain_scores_gemma":[0.9981956,0.0006293538,0.00058598875,0.000114149916,0.000396029,0.000078889134],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00030086975,0.000117882104,0.00046943754,0.000060431674,0.00005902899,0.000010994605,0.00011446098,0.000116864,0.00044760868],"category_scores_gemma":[0.00035549063,0.00009793056,0.00020729828,0.000058091682,0.000051251125,0.00006664769,0.000039281054,0.00012884509,1.5720494e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000074087875,0.000376674,0.000070194474,0.0004349979,0.00039598835,0.000027709146,0.00018588133,0.0017620024,0.9899693,0.0028229638,0.0007652672,0.003114898],"study_design_scores_gemma":[0.00064705376,0.00017842096,0.00024330842,0.00032137503,0.00044269115,0.000115960465,0.0006502452,0.0017073617,0.9906046,0.004633283,0.00034612024,0.000109601446],"about_ca_topic_score_codex":0.0000014248146,"about_ca_topic_score_gemma":4.9928434e-7,"teacher_disagreement_score":0.3000177,"about_ca_system_score_codex":0.000010229306,"about_ca_system_score_gemma":0.000085502885,"threshold_uncertainty_score":0.49010012},"labels":[],"label_agreement":null},{"id":"W3198842025","doi":"10.1002/chem.202103106","title":"Accessing Extended Fused Isoindolinones Via Sequential Anionic Intramolecular Cyclizations","year":2021,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of New Brunswick","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation","keywords":"Intramolecular force; Isoquinoline; Chemistry; Dig; Azepine; Scope (computer science); Combinatorial chemistry; Stereochemistry; Computer science","score_opus":0.025647103432789472,"score_gpt":0.2789192188987736,"score_spread":0.2532721154659841,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W3198842025","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.95602864,0.001383125,0.007748223,0.0006019675,0.00025583233,0.000025728375,0.000019861678,0.00011891911,0.033817682],"genre_scores_gemma":[0.9950081,0.00025287503,0.0015462317,0.00025805391,0.0015514569,0.0000028776922,0.00008619915,0.000078992,0.0012152265],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99807876,0.00023926071,0.00057697296,0.000404304,0.0002679616,0.0004327459],"domain_scores_gemma":[0.99868274,0.00007278277,0.00035632262,0.0003411307,0.00024608467,0.00030096932],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003318069,0.00028904882,0.00028662028,0.000031877425,0.0005574093,0.0003349,0.00046348976,0.00008420051,0.01522516],"category_scores_gemma":[0.00025262212,0.00030339262,0.000248396,0.00018699733,0.00016626513,0.00020202421,0.00016753926,0.0007273354,0.00006253592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00002520758,0.00017525085,0.00017003475,0.00008533587,0.00017370035,0.0018819341,0.0002076804,0.00008205296,0.9861825,0.0000045696347,0.00096675527,0.010044964],"study_design_scores_gemma":[0.0012825796,0.000007533442,0.0007569236,0.00015080941,0.00012042296,0.0031824603,0.0003068246,0.0015963857,0.978789,0.0001348652,0.01328934,0.0003828931],"about_ca_topic_score_codex":4.7556193e-7,"about_ca_topic_score_gemma":1.6572308e-7,"teacher_disagreement_score":0.038979426,"about_ca_system_score_codex":0.00007227405,"about_ca_system_score_gemma":0.00023517842,"threshold_uncertainty_score":0.9999418},"labels":[],"label_agreement":null},{"id":"W4236030577","doi":"10.1515/hc.2002.8.2.110","title":"Graphical Abstracts","year":2002,"lang":"en","type":"article","venue":"Heterocyclic Communications","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry","score_opus":0.07509996256958633,"score_gpt":0.30569574775912123,"score_spread":0.23059578518953489,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4236030577","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.6110197,0.002408215,0.000029124205,0.008661806,0.00005530293,0.00005733348,0.000022862856,0.0002493695,0.37749633],"genre_scores_gemma":[0.9963438,0.0013638107,0.00095105387,0.00037167812,0.00005638008,0.00006376243,0.000020783391,0.000015198201,0.00081354124],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992476,0.000042291722,0.00026618782,0.00015744596,0.00009425603,0.00019220189],"domain_scores_gemma":[0.9981582,0.00039068604,0.000089705034,0.0012396965,0.000026167241,0.00009555775],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00005130143,0.00011405554,0.0001372026,0.00005052236,0.00028367457,0.00002613673,0.0007975326,0.000087793596,0.009023392],"category_scores_gemma":[0.00006667018,0.00011662243,0.00009995322,0.00009050572,0.0002368005,0.00008531886,0.000178645,0.00028991202,0.0005314798],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000021350292,0.0029320498,0.014777677,0.00010228705,0.00043996956,0.000014658487,0.0032453376,0.000026722268,0.76309246,0.0056149857,0.05090617,0.15882632],"study_design_scores_gemma":[0.0007045041,0.000016057851,0.016512316,0.00005404138,0.000059518945,0.00004334311,0.0002009583,0.004662722,0.04816677,0.0010796392,0.92804813,0.0004520038],"about_ca_topic_score_codex":0.000014256905,"about_ca_topic_score_gemma":0.000016140288,"teacher_disagreement_score":0.87714195,"about_ca_system_score_codex":0.000016968484,"about_ca_system_score_gemma":0.0000022948839,"threshold_uncertainty_score":0.9918825},"labels":[],"label_agreement":null},{"id":"W4236620797","doi":"10.3390/m460","title":"2-(cyclohex-2-enyloxy)-isoindole-1,3-dione","year":2006,"lang":"en","type":"article","venue":"Molbank","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Chemistry; Acetonitrile; Isoindole; Cyclohexene; Nitrogen; Nuclear chemistry; Organic chemistry; Chromatography; Catalysis","score_opus":0.00793122247138971,"score_gpt":0.22382879732468744,"score_spread":0.21589757485329772,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4236620797","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.8225095,0.0009915597,0.00007536824,0.0009070869,0.00014118166,0.000041554533,0.000023466173,0.00019154474,0.17511868],"genre_scores_gemma":[0.9898808,0.000025158146,0.00056733517,0.00028640727,0.00075068435,0.000035179808,0.00004812372,0.000032953747,0.008373358],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99890745,0.000017415701,0.00025433232,0.00030540072,0.00017842086,0.0003369794],"domain_scores_gemma":[0.9994333,0.00009825409,0.0000986963,0.000273361,0.00004307779,0.00005333637],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009337556,0.00019647728,0.00022569328,0.00004145786,0.00013528044,0.000033391665,0.00023491426,0.0001358523,0.008603621],"category_scores_gemma":[0.000018901692,0.00019141997,0.000115455055,0.00010508151,0.00010507626,0.00010739593,0.00005572474,0.00018208202,0.00037784036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000058563583,0.00034334566,0.012512382,0.00010816398,0.0000954188,0.0000978864,0.00006761265,0.00008477378,0.9087168,0.0026218533,0.065914206,0.009378978],"study_design_scores_gemma":[0.00095288624,0.000013848858,0.01818789,0.000049916085,0.00004435803,0.00002664159,0.00006411327,0.00029755797,0.68957525,0.0023663987,0.2880096,0.00041148637],"about_ca_topic_score_codex":0.00013844605,"about_ca_topic_score_gemma":0.000007738585,"teacher_disagreement_score":0.22209541,"about_ca_system_score_codex":0.000033010907,"about_ca_system_score_gemma":0.00002403188,"threshold_uncertainty_score":0.99230266},"labels":[],"label_agreement":null},{"id":"W4240346549","doi":"10.1139/cjc-79-11-1528","title":"Asymmetric synthesis of 3-aryl-substituted 2,3-dihydro-1&lt;i&gt;H&lt;/i&gt;-isoindol-1-ones","year":2001,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Chemistry; Aryl; Medicinal chemistry; Stereochemistry; Computational chemistry; Organic chemistry","score_opus":0.014573132397355705,"score_gpt":0.23069487739479705,"score_spread":0.21612174499744136,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4240346549","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.92951113,0.0070063067,0.000027551689,0.00066634046,0.00026019663,0.000049144703,0.00013471227,0.000022787628,0.062321845],"genre_scores_gemma":[0.997192,0.0006481052,0.00028189164,0.00008564634,0.00074838765,0.000009571129,0.000014170675,0.000057418616,0.0009627976],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99739754,0.000031723666,0.0010901301,0.00033821925,0.0004316005,0.0007107998],"domain_scores_gemma":[0.99628204,0.0006479246,0.0009967784,0.00045433888,0.00046199647,0.0011569113],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00045366687,0.00041905505,0.0008809288,0.00037193604,0.00020482411,0.000053637355,0.00096334243,0.00041558783,0.0068387296],"category_scores_gemma":[0.0015647087,0.0004289601,0.00046289296,0.0006653989,0.00047255214,0.00024369745,0.00003394593,0.0005085808,0.000025240874],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000089650035,0.00010888636,0.0046940134,0.0002647712,0.0004626951,0.00068808085,0.00017247794,0.00008941305,0.9739759,0.000026379674,0.01017402,0.009253702],"study_design_scores_gemma":[0.00073419453,0.000017059858,0.002101638,0.00034978945,0.00018136812,0.0008298695,0.00011657086,0.00006418593,0.9119928,0.000107225635,0.08309759,0.00040773366],"about_ca_topic_score_codex":0.00016210157,"about_ca_topic_score_gemma":0.00033132528,"teacher_disagreement_score":0.07292357,"about_ca_system_score_codex":0.0002656266,"about_ca_system_score_gemma":0.0015732723,"threshold_uncertainty_score":0.99981624},"labels":[],"label_agreement":null},{"id":"W4382072228","doi":"10.2174/1385272827666230623165030","title":"On the use of Organically-Modified Aluminosilicate Clays in the RegioselectiveKnoevenagel-type Terpenylation of Cyclic 1,3-dicarbonyls En Route to Cannabinoids","year":2023,"lang":"en","type":"article","venue":"Current Organic Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Knoevenagel condensation; Regioselectivity; Aluminosilicate; Organic chemistry; Catalysis","score_opus":0.0813813271921309,"score_gpt":0.3119468814169941,"score_spread":0.23056555422486322,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4382072228","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9958999,0.00007108475,0.000016494094,0.002924579,0.00008397369,0.00021699924,0.00004504892,0.000056273333,0.00068562926],"genre_scores_gemma":[0.9992754,0.00007370323,0.000012804129,0.00017483,0.00010822505,0.000052602958,0.000060123784,0.000034115732,0.00020823379],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99826795,0.00012989088,0.0005232093,0.00040177692,0.0003609449,0.00031625424],"domain_scores_gemma":[0.99732155,0.0015446742,0.0002762524,0.00067485607,0.00011279381,0.000069885944],"candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004186798,0.00024926278,0.00034181663,0.000060768947,0.00007431876,0.000021207088,0.0007654792,0.00021756387,0.00090170605],"category_scores_gemma":[0.0016861674,0.00017363107,0.00011105283,0.0010286809,0.00015745404,0.00004895501,0.0001349834,0.00062153355,0.000023167962],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00008924507,0.0002412357,0.002057709,0.00018384228,0.000049625334,0.0000025311358,0.0010386669,0.00016324605,0.98855054,0.000072458606,0.006305884,0.0012450326],"study_design_scores_gemma":[0.00039236332,0.000028350309,0.01647472,0.00018757451,0.000048983187,0.0000023381285,0.00019550673,0.0007895089,0.9778015,0.00017168836,0.0037083477,0.00019913886],"about_ca_topic_score_codex":0.000020017193,"about_ca_topic_score_gemma":0.000004950885,"teacher_disagreement_score":0.01441701,"about_ca_system_score_codex":0.00009737146,"about_ca_system_score_gemma":0.00016979434,"threshold_uncertainty_score":0.9873049},"labels":[],"label_agreement":null},{"id":"W4394741783","doi":"10.1139/cjc-2023-0146","title":"Benzotriazepine synthesis, conformational analysis, and biological properties","year":2024,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":true,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"Université de Montréal","funders":"Institute of Health Services and Policy Research; Natural Sciences and Engineering Research Council of Canada; Fonds de recherche du Québec – Nature et technologies; Canadian Institutes of Health Research; Universities Space Research Association; Centre in Green Chemistry and Catalysis","keywords":"Chemistry; Ring (chemistry); Amide; Biological activity; Peptide; Stereochemistry; Combinatorial chemistry; Organic chemistry; Biochemistry; In vitro","score_opus":0.027063965464305964,"score_gpt":0.2407601637666056,"score_spread":0.21369619830229963,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4394741783","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9797835,0.012251967,0.00004374476,0.0011818404,0.00008500484,0.00001698955,0.00010757029,0.000016727256,0.006512663],"genre_scores_gemma":[0.99891925,0.00024064776,0.00010245868,0.00007754122,0.00035514391,0.00000463325,0.000014000347,0.000009435028,0.00027688823],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99909395,0.000016192242,0.000405602,0.00014182425,0.00011866105,0.00022379094],"domain_scores_gemma":[0.9990502,0.00020295837,0.0001239728,0.00009047859,0.000109553745,0.00042284201],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00025529097,0.00014964992,0.00032219285,0.00015697618,0.00009607199,0.00012233308,0.00020124932,0.00014878863,0.0075025484],"category_scores_gemma":[0.00033147796,0.00011521495,0.00018294938,0.0002017868,0.00025228897,0.00015062062,0.000012786161,0.00028619633,0.0000065077024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00007740197,0.000038610648,0.019596178,0.00091807113,0.004767094,0.00053715263,0.0012146335,0.00008146066,0.94251853,0.0002144322,0.008090316,0.021946095],"study_design_scores_gemma":[0.000215088,0.000012977101,0.0035626036,0.00030540192,0.0005050382,0.00050525204,0.00055191526,0.0007080617,0.9245111,0.00017783146,0.06864807,0.00029666425],"about_ca_topic_score_codex":0.00012010468,"about_ca_topic_score_gemma":0.00006992002,"teacher_disagreement_score":0.060557753,"about_ca_system_score_codex":0.000069796544,"about_ca_system_score_gemma":0.00066572335,"threshold_uncertainty_score":0.99340475},"labels":[],"label_agreement":null},{"id":"W4404579619","doi":"10.20944/preprints202411.1645.v1","title":"Synthesis and Pharmacology of Clinical Drugs Containing Isoindoline Heterocycle Core","year":2024,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":true,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Isoindoline; Pharmacology; Chemistry; Drug; Combinatorial chemistry; Medicine; Organic chemistry","score_opus":0.20448383923367106,"score_gpt":0.444903209804802,"score_spread":0.24041937057113097,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4404579619","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.97910684,0.0015543416,0.0000029530563,0.0007967079,0.0013651534,0.00026619813,0.00022113223,0.00021152498,0.016475148],"genre_scores_gemma":[0.9960882,0.0014310625,0.00018520078,0.00023692871,0.0010956785,0.00025990157,0.000031553493,0.00009116541,0.00058028003],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.995883,0.0002486874,0.0016561672,0.0014646659,0.0002839518,0.00046354733],"domain_scores_gemma":[0.9956768,0.0022589269,0.00090215076,0.0007529173,0.00015085943,0.00025833613],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0014559805,0.00057115144,0.0016379966,0.00016703003,0.00008681757,0.000016691432,0.0007312247,0.00088753377,0.010581597],"category_scores_gemma":[0.0007777277,0.0005802374,0.00054298923,0.000080155485,0.0006611119,0.00004754404,0.003860374,0.0021305906,0.0002758307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00090714474,0.0005745,0.48555055,0.0041000876,0.0029570982,0.00009898093,0.0023517217,0.000096263524,0.48791078,0.00013623135,0.0007553078,0.0145613225],"study_design_scores_gemma":[0.00086582295,0.000025651489,0.031587817,0.00081480015,0.00085916085,0.000017325745,0.00048816888,0.001513834,0.9571495,0.001396399,0.004686485,0.00059501594],"about_ca_topic_score_codex":0.000090648915,"about_ca_topic_score_gemma":0.0000030333258,"teacher_disagreement_score":0.46923873,"about_ca_system_score_codex":0.000055558343,"about_ca_system_score_gemma":0.00022883649,"threshold_uncertainty_score":0.9996649},"labels":[],"label_agreement":null},{"id":"W4411657342","doi":"10.51847/6mysils","title":"10.51847/6mySiLS","year":2000,"lang":"en","type":"article","venue":"Time to knit","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":true,"route_about_ca":false,"ca_institutions":"","funders":"","keywords":"Indole test; Quantitative structure–activity relationship; Stereochemistry; Dual (grammatical number); Chemistry; Topoisomerase; Biochemistry; Philosophy; Enzyme","score_opus":0.0098428546237906,"score_gpt":0.2152387368440463,"score_spread":0.20539588222025568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4411657342","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.043131433,0.000087365566,8.690445e-8,0.0004118846,0.0000015516579,0.000038417278,0.000022542887,0.00012779492,0.9561789],"genre_scores_gemma":[0.0041632373,9.590411e-7,0.00008591419,0.00013883432,0.00020917515,0.00002429947,0.000013822349,0.00002038302,0.9953434],"study_design_codex":"design_other","study_design_gemma":"not_applicable","domain_scores_codex":[0.9992919,0.000017392915,0.00014368402,0.00021124796,0.000102151214,0.00023362711],"domain_scores_gemma":[0.999528,0.00009528605,0.00002521993,0.00020653548,0.000021475107,0.00012349941],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00006656559,0.00012964412,0.00016553995,0.000028675464,0.00006913506,0.000019582507,0.0002103895,0.000069450485,0.9995747],"category_scores_gemma":[0.000028767367,0.00012874616,0.00006427823,0.00007862149,0.000039819504,0.000055217264,0.000023373936,0.00008516093,0.9715257],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000066436536,0.00006181501,9.081339e-7,0.00000929602,0.000038882215,0.0000063494394,0.000027513364,0.000024210165,0.026904602,7.341935e-7,0.06706014,0.9057991],"study_design_scores_gemma":[0.00018892129,0.00001991782,0.000050028975,0.000012970036,0.000017260047,0.000004571768,0.0000015385518,0.00009343719,0.023453338,0.0000031398065,0.97599286,0.00016199354],"about_ca_topic_score_codex":0.00000600332,"about_ca_topic_score_gemma":2.0388052e-8,"teacher_disagreement_score":0.90893275,"about_ca_system_score_codex":0.000017257104,"about_ca_system_score_gemma":0.000015517586,"threshold_uncertainty_score":0.5250116},"labels":[],"label_agreement":null},{"id":"W4413675859","doi":"10.64628/aam.79de3e7ws","title":"In the end, it was Khashoggi’s ‘friends’ who silenced him","year":2018,"lang":"en","type":"preprint","venue":"","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Toronto Metropolitan University","funders":"","keywords":"Internet privacy; Psychology; Business; Sociology; Computer science","score_opus":0.04019735854683836,"score_gpt":0.3256020007513593,"score_spread":0.28540464220452094,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W4413675859","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.53139395,0.00032153254,0.000030360592,0.010719958,0.0005684957,0.00021002811,0.00009768601,0.00008995794,0.45656806],"genre_scores_gemma":[0.9814401,0.0003579482,0.0003600823,0.0043298365,0.0014428964,0.00031026624,0.00007758149,0.00004488299,0.01163637],"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.997687,0.00014882507,0.0005392168,0.00076874846,0.00036988303,0.00048636264],"domain_scores_gemma":[0.9979621,0.0006829848,0.00025940445,0.0009305979,0.000082742845,0.00008217384],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00057806657,0.00046769067,0.0005622989,0.00010006833,0.00012292496,0.00009771305,0.0014951078,0.0005945804,0.062404852],"category_scores_gemma":[0.00014405871,0.00032964593,0.00024497448,0.00010605933,0.00041968748,0.000093194576,0.00065242907,0.0010822536,0.00032573583],"study_design_candidate":"not_applicable","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020651364,0.0008614712,0.004357101,0.00097159477,0.00072717,0.0001887645,0.017996801,0.00007736426,0.06362591,0.0021034046,0.9029477,0.0059362063],"study_design_scores_gemma":[0.0013310098,0.0000562726,0.0034492395,0.0006463375,0.00023237616,0.000035776528,0.0060566594,0.0014554819,0.5649781,0.008346458,0.41181633,0.001595927],"about_ca_topic_score_codex":0.0001886305,"about_ca_topic_score_gemma":0.000066556044,"teacher_disagreement_score":0.50135225,"about_ca_system_score_codex":0.00006115527,"about_ca_system_score_gemma":0.00014393403,"threshold_uncertainty_score":0.99991554},"labels":[],"label_agreement":null},{"id":"W651849209","doi":"10.71781/12080","title":"Synthèse de mimes peptidiques pyrrolo[3,2-e][1,4]diazépin-2-one","year":2008,"lang":"en","type":"dissertation","venue":"Open MIND","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Amine gas treating; Chemistry; Reductive amination; Primary (astronomy); Peptidomimetic; Carboxylate; Synthon; Acylation; Stereochemistry; Amino acid; Peptide; Combinatorial chemistry; Medicinal chemistry; Organic chemistry; Catalysis; Biochemistry","score_opus":0.0539138176297206,"score_gpt":0.3482608339528658,"score_spread":0.2943470163231452,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W651849209","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.70345616,0.0018155219,0.000001158273,0.0001503002,0.00016971602,0.00020587274,0.00013691548,0.000011597631,0.29405275],"genre_scores_gemma":[0.7885045,0.0041434313,0.008984038,0.00022656558,0.0011359266,0.00039347063,0.0038783413,0.00024817832,0.19248556],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99776703,0.00009171469,0.0005406064,0.0007805422,0.00027224474,0.00054785406],"domain_scores_gemma":[0.99837554,0.00031205884,0.00047513988,0.0004944953,0.00013199692,0.00021079995],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00024613398,0.00053167064,0.000816382,0.00011854748,0.00027986735,0.0001764358,0.001225594,0.00076536176,0.056794014],"category_scores_gemma":[0.00020739558,0.00057560083,0.00024081438,0.00010732938,0.00012769386,0.00024370811,0.00012273353,0.0006206029,0.0008996474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.0009848143,0.0010113175,0.0010900287,0.00047394724,0.0012729726,0.0003060547,0.011369695,0.000007682042,0.6948646,0.000023227147,0.032899123,0.25569656],"study_design_scores_gemma":[0.000444538,0.000031236454,0.0013625841,0.0004348259,0.00020326891,0.000022965427,0.0013681935,0.000020739684,0.8033628,0.00006918587,0.19206333,0.000616342],"about_ca_topic_score_codex":0.00013833275,"about_ca_topic_score_gemma":0.0001948802,"teacher_disagreement_score":0.25508022,"about_ca_system_score_codex":0.00010670169,"about_ca_system_score_gemma":0.0005568153,"threshold_uncertainty_score":0.9998783},"labels":[],"label_agreement":null},{"id":"W6884472617","doi":"10.1021/jo701467d.s002","title":"1,3,5-Trisubstituted 1,4-Diazepin-2-ones","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stantec (Canada)","funders":"","keywords":"Sequence (biology); Yield (engineering); Cascade; Group (periodic table); Annulation","score_opus":0.04639268678172778,"score_gpt":0.2759710880925798,"score_spread":0.22957840131085203,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6884472617","genre_codex":"dataset","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":null,"domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.17390163,0.0022661213,0.000011748911,0.00377282,0.00034467224,0.0002759606,0.617796,0.0013946369,0.20023638],"genre_scores_gemma":[0.98179245,0.00002863434,0.00009783436,0.00032882515,0.00067738816,0.00027788518,0.012304155,0.000043579803,0.004449263],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.999084,0.000017785485,0.00018310796,0.0002863849,0.00013537839,0.00029333442],"domain_scores_gemma":[0.9990039,0.00044709892,0.00009868147,0.0002601905,0.000076047254,0.00011409762],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.000026155807,0.00017285797,0.00018211511,0.00004419649,0.000090362424,0.000020512736,0.00029759924,0.00013114937,0.83381593],"category_scores_gemma":[0.0010247998,0.000118843745,0.00010260129,0.00008254406,0.000020746042,0.00016303666,0.00008050092,0.00008489348,0.009157637],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000022286406,0.000053210042,0.00036665305,0.00009927676,0.00006252096,0.000030378222,0.000049523707,6.230524e-7,0.24238645,0.000036702713,0.7209896,0.035902802],"study_design_scores_gemma":[0.00039170342,0.0000051769125,0.0018539539,0.0006492541,0.0000071004247,0.000007073658,0.000010651877,0.000009412359,0.42156062,0.000061871855,0.57525015,0.00019301864],"about_ca_topic_score_codex":0.0000015825989,"about_ca_topic_score_gemma":0.0000013852314,"teacher_disagreement_score":0.82465833,"about_ca_system_score_codex":0.000030463743,"about_ca_system_score_gemma":0.000045127654,"threshold_uncertainty_score":0.99161386},"labels":[],"label_agreement":null},{"id":"W6884492706","doi":"10.1021/jo200424q.s002","title":"Pyrrolo[3,2-&lt;i&gt;e&lt;/i&gt;][1,4]diazepin-2-one Synthesis: A Head-to-Head Comparison of Soluble versus Insoluble Supports","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Université de Montréal; Université du Québec à Montréal","funders":"","keywords":"Reaction conditions; Decomposition; Cleavage (geology); Solid-phase synthesis; Precipitation; Nuclear magnetic resonance spectroscopy; Branching (polymer chemistry)","score_opus":0.08273094509533191,"score_gpt":0.3276024122130476,"score_spread":0.24487146711771568,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6884492706","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.7463712,0.005421313,0.000019522133,0.004428638,0.0011676616,0.0011808481,0.1633574,0.001042331,0.07701107],"genre_scores_gemma":[0.99261993,0.000038434682,0.00037499447,0.00023201945,0.00043823037,0.0007622006,0.0039027228,0.00012099527,0.0015104784],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.99633515,0.0001208442,0.00096627616,0.0009120896,0.00062071753,0.0010449019],"domain_scores_gemma":[0.99556285,0.0020653293,0.0005821846,0.00094926707,0.0003278471,0.00051252486],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00019951873,0.00058482797,0.0011442692,0.00022713159,0.00022938961,0.000051659812,0.0009368261,0.00046854233,0.36839318],"category_scores_gemma":[0.0028037317,0.00051738584,0.0003747894,0.00033642453,0.00009446353,0.0003291801,0.00039957243,0.00026499384,0.0036128485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00071170233,0.0006673409,0.00045558714,0.00053105905,0.00034761662,0.000028343788,0.00040244265,0.00001917111,0.5290697,0.000035111665,0.4474066,0.020325324],"study_design_scores_gemma":[0.0015565702,0.00016840144,0.002443008,0.002390777,0.000095554744,0.000005688324,0.000052103576,0.000103609505,0.5735159,0.000024589835,0.41907075,0.00057303393],"about_ca_topic_score_codex":0.000012067545,"about_ca_topic_score_gemma":0.00013850525,"teacher_disagreement_score":0.36478034,"about_ca_system_score_codex":0.0001589528,"about_ca_system_score_gemma":0.00025778176,"threshold_uncertainty_score":0.9997278},"labels":[],"label_agreement":null},{"id":"W6903054236","doi":"10.1021/ol061036k.s003","title":"1,4-Diazepinone and Pyrrolodiazepinone\\nSyntheses via Homoallylic Ketones from\\nCascade Addition of Vinyl Grignard\\nReagent to α-Aminoacyl-β-amino Esters","year":2016,"lang":"en","type":"article","venue":"Figshare","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"Stantec (Canada)","funders":"","keywords":"Intramolecular force; Moiety; Olefin fiber; Ketone; Cascade; Reagent","score_opus":0.030444817943732994,"score_gpt":0.25354425348147347,"score_spread":0.22309943553774048,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6903054236","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.72151464,0.0011376532,0.00003542104,0.0014967248,0.00012462505,0.0003767278,0.27176172,0.00022321941,0.0033292933],"genre_scores_gemma":[0.9891332,0.00010465279,0.00033590652,0.00039510228,0.00043938225,0.0004857752,0.008569067,0.00007314525,0.00046378656],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9976498,0.000096512194,0.0005908766,0.00076196645,0.00035849048,0.0005423407],"domain_scores_gemma":[0.99692786,0.0016576647,0.000366852,0.0005348533,0.00015447946,0.0003582778],"candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00009023869,0.00046608143,0.00064442126,0.00017646592,0.00013948896,0.00004430536,0.00048108326,0.00030786428,0.24805205],"category_scores_gemma":[0.0010428115,0.0003736541,0.00019474416,0.00015736128,0.000095561634,0.000345691,0.0002923122,0.0001694609,0.0009556152],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00020142087,0.00024848923,0.0011253126,0.00040181214,0.00032855562,0.000051184554,0.00078442926,0.0000046763735,0.7905618,0.000008319489,0.10627651,0.10000748],"study_design_scores_gemma":[0.0009387195,0.00011847098,0.046260778,0.0028773358,0.000087815395,0.000023096874,0.00015694722,0.000050198163,0.8754814,0.000117423035,0.0732263,0.00066150073],"about_ca_topic_score_codex":0.000064442356,"about_ca_topic_score_gemma":0.000023269653,"teacher_disagreement_score":0.26761857,"about_ca_system_score_codex":0.00007045475,"about_ca_system_score_gemma":0.00005725843,"threshold_uncertainty_score":0.99987155},"labels":[],"label_agreement":null},{"id":"W6923605526","doi":"10.14288/1.0345563","title":"British Columbia Federationist","year":2017,"lang":"en","type":"article","venue":"Open Collections","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Government (linguistics); Work (physics); Agency (philosophy)","score_opus":0.03052845239140739,"score_gpt":0.3007353511148974,"score_spread":0.27020689872349,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6923605526","genre_codex":"other","genre_gemma":"other","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"other","genre_consensus":"other","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.022474715,0.00001809066,0.000020320147,0.00043953245,0.0002017386,0.000108333355,0.000038243063,0.000038093167,0.9766609],"genre_scores_gemma":[0.11313445,0.000029108605,0.00041690643,0.00011247249,0.00016618804,0.0001742461,0.000013006692,0.000012573819,0.885941],"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","domain_scores_codex":[0.99943656,0.000014559208,0.00012864597,0.00021389594,0.000066204644,0.00014013368],"domain_scores_gemma":[0.9993786,0.000053315467,0.00011450304,0.0003252749,0.0000655001,0.00006281328],"candidate_categories":["sts","scholarly_communication","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000079088684,0.000055944638,0.00013384227,0.0000022483737,0.119750924,0.23980966,0.00056933734,0.00006205446,0.056218877],"category_scores_gemma":[0.00017568759,0.000097897355,0.000047547306,0.000046891982,0.00013103323,0.0003257843,0.00019553195,0.00010327851,0.000021648917],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.000004354544,0.00008546717,0.0016422551,0.000004660749,0.000045780762,0.000008139278,0.000008093399,0.0000012959895,0.0017411965,0.0000027154342,0.99360394,0.002852082],"study_design_scores_gemma":[0.000773826,0.000014478724,0.004763066,0.00003487999,0.000027888262,0.00005221502,0.0001316531,0.00018578583,0.0062776967,0.0011337171,0.98639774,0.00020705054],"about_ca_topic_score_codex":0.44481656,"about_ca_topic_score_gemma":0.63177955,"teacher_disagreement_score":0.23948388,"about_ca_system_score_codex":0.00003443447,"about_ca_system_score_gemma":0.00009109464,"threshold_uncertainty_score":0.94464386},"labels":[],"label_agreement":null},{"id":"W6967594132","doi":"10.5281/zenodo.10164337","title":"From Wood to Tetrahydro-2-benzazepines in Three Waste-Free Steps: Modular Synthesis of Biologically Active Lignin-Derived Scaffolds","year":2019,"lang":"en","type":"article","venue":"Zenodo (CERN European Organization for Nuclear Research)","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":false,"route_ca_aff":true,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":false,"ca_institutions":"McGill University","funders":"","keywords":"Biological activity; Modular design; Component (thermodynamics); Biological materials","score_opus":0.026054817909613087,"score_gpt":0.2455025926337694,"score_spread":0.2194477747241563,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W6967594132","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.9607071,0.00008557904,0.00007291174,0.0008219382,0.00005994236,0.00034333084,0.0007729216,0.00024180618,0.036894448],"genre_scores_gemma":[0.99832106,0.000045135424,0.00047322977,0.00009815515,0.00014116678,4.4316164e-7,0.00028132932,0.0005433781,0.00009607889],"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","domain_scores_codex":[0.9979391,0.00023833972,0.0004336808,0.00064022915,0.0003275933,0.00042106796],"domain_scores_gemma":[0.99841505,0.00026237746,0.00019270752,0.0007321849,0.0002254199,0.00017225224],"candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00036447862,0.00024811766,0.00043709873,0.0002529505,0.00031048566,0.00011849246,0.0016488201,0.00017142238,0.024660114],"category_scores_gemma":[0.0012418715,0.0002425139,0.00010369736,0.00046641065,0.00016071841,0.00019436951,0.0012856838,0.00020022769,0.0014179682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00024550752,0.0003020178,0.00013534956,0.000085668755,0.0001586599,0.000010165285,0.0011038017,0.00021208609,0.95709383,0.0001607596,0.006000963,0.034491185],"study_design_scores_gemma":[0.0012367532,0.00025842583,0.007803416,0.00025209217,0.000038657177,0.000007823651,0.002251401,0.0006598338,0.93929726,0.0005693104,0.04717752,0.00044752753],"about_ca_topic_score_codex":0.000064588676,"about_ca_topic_score_gemma":0.0000021000876,"teacher_disagreement_score":0.041176554,"about_ca_system_score_codex":0.00010663363,"about_ca_system_score_gemma":0.000006569036,"threshold_uncertainty_score":0.99935955},"labels":[],"label_agreement":null},{"id":"W7098384974","doi":"","title":"ii Uncertainty &amp;quot; in health promotion: Nutrition","year":2016,"lang":"en","type":"article","venue":"","topic":"Synthesis and pharmacology of benzodiazepine derivatives","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"route_ca_aff":false,"route_ca_fund":false,"route_ca_venue":false,"route_about_ca":true,"ca_institutions":"","funders":"","keywords":"Health promotion; Promotion (chess); Health policy; Public health; Global health","score_opus":0.04726730810037957,"score_gpt":0.32281539419852134,"score_spread":0.2755480860981418,"validation_status":"score_only:v0-immature-baseline","prediction":{"id":"W7098384974","genre_codex":"empirical","genre_gemma":"empirical","domain_codex":null,"domain_gemma":null,"model_version":"codex-gemma-dda1882f352a","genre_candidate":"empirical","genre_consensus":"empirical","domain_candidate":null,"domain_consensus":null,"prediction_status":"machine_predicted_unvalidated","genre_scores_codex":[0.94292736,0.00021779175,0.00023806539,0.038507603,0.00007818451,0.00012242014,0.000024613146,0.000114944654,0.017769044],"genre_scores_gemma":[0.9883215,0.00026528264,0.0006326665,0.00031529082,0.00018260673,0.00007701644,0.000016155742,0.000009789794,0.010179734],"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","domain_scores_codex":[0.99917066,0.000043093412,0.000249525,0.00021703282,0.00009154058,0.00022813235],"domain_scores_gemma":[0.9995725,0.00010880804,0.000078101504,0.00014098418,0.000027396294,0.00007221338],"candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00018512386,0.00010066533,0.00016377177,0.0000465709,0.000088872526,0.000005817461,0.00010009417,0.0000695162,0.017171886],"category_scores_gemma":[0.000057831618,0.0000683433,0.000042714517,0.00007546339,0.00005696497,0.00009115217,0.00003294048,0.000068745125,0.000081101665],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_system_candidate":false,"about_ca_system_consensus":false,"study_design_scores_codex":[0.00014647504,0.0029441318,0.010142292,0.00056041474,0.00005894972,0.000006824095,0.0009892877,0.000008188602,0.7757861,0.0038470102,0.06391211,0.1415982],"study_design_scores_gemma":[0.004040859,0.00017847394,0.0031856766,0.0008601108,0.000006464738,0.000017759303,0.0002900216,0.000089363755,0.3494034,0.0051318267,0.6363398,0.00045623007],"about_ca_topic_score_codex":0.000056969686,"about_ca_topic_score_gemma":0.00010343873,"teacher_disagreement_score":0.5724277,"about_ca_system_score_codex":0.000100566795,"about_ca_system_score_gemma":0.000046155666,"threshold_uncertainty_score":0.98372656},"labels":[],"label_agreement":null}]}